FLY_GENE SYMBOL FULL_NAME URL SECONDARY_FBGNS GENE_CLASS GO_MOLECULAR_FUNCTION GO_BIOLOGICAL_PROCESS GO_CELLULAR_COMPONENT SYNONYMS PROTEIN_DOMAINS CG_SYMBOL DATE_LAST_UPDATED DATA_VERSION ZEBRAFISH_ORTHOLOGS YEAST_ORTHOLOGS WORM_ORTHOLOGS XENOPUS_ORTHOLOGS MOUSE_ORTHOLOGS HUMAN_ORTHOLOGS RNA_EXPRESSION_STAGE RNA_EXPRESSION_TISSUE PROTEIN_EXPRESSION_STAGE PROTEIN_EXPRESSION_TISSUE FLYBASE_EXP_LINK PHENO_CLASS PHENO_MANIFEST DRSC SCREEN AVG_Z_SCORE_BASELINE_S2R AVG_Z_SCORE_10_INSULIN_S2R AVG_Z_SCORE_BASELINE_S2R_MTDER AVG_Z_SCORE_10_EGF_S2R_MTDER AVG_Z_SCORE_10_EGF_KC AVG_Z_SCORE_30_EGF_KC HUMAN_DISEASE HUMAN_ORTHOLOG_DESCRIPTION FBgn0002413 dco discs overgrown http://flybase.org/reports/FBgn0002413 "FBgn0011349, FBgn0011508, FBgn0024895, FBgn0027967, FBgn0028129" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein binding ; GO:0005515 | inferred from physical interaction with Bdbt kinase activity ; GO:0016301 | inferred from mutant phenotype protein binding ; GO:0005515 | inferred from physical interaction with per protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity protein kinase activity ; GO:0004672 | inferred from direct assay protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement" negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype regulation of ecdysteroid secretion ; GO:0007555 | inferred from mutant phenotype cellular response to light stimulus ; GO:0071482 | inferred from direct assay protein phosphorylation ; GO:0006468 | traceable author statement positive regulation of cell division ; GO:0051781 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement peptidyl-serine phosphorylation ; GO:0018105 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 protein phosphorylation ; GO:0006468 | inferred from direct assay positive regulation of proteasomal ubiquitin-dependent protein catabolic process ; GO:0032436 | inferred from direct assay regulation of cell shape ; GO:0008360 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 regulation of protein import into nucleus ; GO:0042306 | traceable author statement circadian rhythm ; GO:0007623 | traceable author statement regulation of circadian rhythm ; GO:0042752 | inferred from mutant phenotype establishment of imaginal disc-derived wing hair orientation ; GO:0001737 | inferred from mutant phenotype circadian rhythm ; GO:0007623 | inferred from mutant phenotype positive regulation of cell growth ; GO:0030307 | inferred from mutant phenotype cell communication ; GO:0007154 | inferred from mutant phenotype circadian rhythm ; GO:0007623 | inferred from mutant phenotype inferred from physical interaction with per endocytosis ; GO:0006897 | inferred from biological aspect of ancestor with PANTHER:PTN000226268 rhythmic behavior ; GO:0007622 | traceable author statement circadian rhythm ; GO:0007623 | inferred from direct assay locomotor rhythm ; GO:0045475 | non-traceable author statement behavioral response to cocaine ; GO:0048148 | non-traceable author statement phosphorylation ; GO:0016310 | inferred from direct assay eclosion rhythm ; GO:0008062 | traceable author statement behavioral response to cocaine ; GO:0048148 | inferred from mutant phenotype establishment of ommatidial planar polarity ; GO:0042067 | inferred from mutant phenotype sleep ; GO:0030431 | non-traceable author statement protein autophosphorylation ; GO:0046777 | inferred from direct assay positive regulation of actin filament polymerization ; GO:0030838 | inferred from mutant phenotype positive regulation of protein catabolic process ; GO:0045732 | inferred from direct assay negative regulation of protein phosphorylation ; GO:0001933 | inferred from mutant phenotype imaginal disc growth ; GO:0007446 | inferred from mutant phenotype Wnt signaling pathway ; GO:0016055 | inferred from mutant phenotype positive regulation of protein catabolic process ; GO:0045732 | inferred from mutant phenotype cytoplasm ; GO:0005737 | traceable author statement cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | traceable author statement nucleus ; GO:0005634 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "dco, CK1epsilon, DBT, dbt, Dbt, CKIepsilon, DBT/CK1epsilon, ddbt, ck1epsilon, DCO/CKIe, CG2048, l(3)j3B9, l(3)discs overgrown, l(3)S144701, l(3)S053813, 1460/09, 1447/01, 1396/02, 0915/10, 0538/13, l(3)dco, dco-1, l(3)discs overgrown-1, l(3)dco-1, l(3)rK215, dCKIepsilon, Dco/CK1, DCO, Dco, CK1delta/epsilon" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG2048 27-Aug-18 DroID_v2018_08 "Drer\ttbk1a, Drer\csnk1da, Drer\csnk1e, Drer\vrk3, Drer\csnk1db, Drer\ttbk2b, Drer\vrk2, Drer\csnk1a1, Drer\ttbk1b, Drer\vrk1" Scer\HRR25 "Cele\F22H10.1, Cele\kin-19, Cele\kin-20, Cele\T05C12.1, Cele\ZC373.3, Cele\F53C3.1, Cele\spe-6" "Xtro\vrk1, Xtro\csnk1e, Xtro\vrk2, Xtro\ttbk2, Xtro\csnk1d, Xtro\vrk3, Xtro\csnk1a1" "Mmus\Vrk3, Mmus\Vrk1, Mmus\Csnk1d, Mmus\Vrk2, Mmus\Csnk1e, Mmus\Ttbk2, Mmus\Csnk1a1, Mmus\Ttbk1" "Hsap\VRK1, Hsap\TTBK1, Hsap\CSNK1E, Hsap\VRK2, Hsap\CSNK1D, Hsap\TTBK2, Hsap\CSNK1A1, Hsap\LOC400927-CSNK1E, Hsap\VRK3, Hsap\CSNK1A1L" adult stage " adult lateral neuron

, photoreceptor cell

, adult brain | restricted

" "viable,size defective,fertile,circadian rhythm defective,cell polarity defective,lethal,recessive,locomotor rhythm defective,eclosion rhythm defective,cell size defective,somatic clone,cell autonomous,lethal - all die before end of pupal stage,some die during pupal stage,developmental rate defective,lethal - all die before end of larval stage,some die during larval stage,temperature conditional,partially lethal - majority die,visible,hyperplasia,wild-type,polyphasic,increased cell number,semidominant,partially lethal - majority live,behavior defective,cell death defective,flight defective,dominant,partially lethal" "wing,class IV dendritic arborizing neuron,somatic clone,ommatidium,neuron,lateral,wing disc,wing hair,cell non-autonomous,cell autonomous,crossvein,larva,imaginal disc,wing pouch,eye,vibrissae,wing vein,tarsal segment,adult external head,leg,unguis,supernumerary,larval head,dorsal organ,terminal organ,labral segment,embryonic/larval cuticle,dorsal,dorsal bridge,egg,germline clone,eye photoreceptor cell,wing margin bristle,trichogen cell,mesothoracic tergum" DRSC16929 I 1.989390382 1.027456985 0.858794289 0.581831233 -0.192138506 0.221942657 FBgn0001308 Khc Kinesin heavy chain http://flybase.org/reports/FBgn0001308 "FBgn0021886, FBgn0021889, FBgn0028613" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001752, InterPro:IPR019821 ATP-dependent microtubule motor activity, plus-end-directed ; GO:0008574 | traceable author statement tropomyosin binding ; GO:0005523 | inferred from physical interaction with Tm1 microtubule motor activity ; GO:0003777 | inferred from direct assay motor activity ; GO:0003774 | non-traceable author statement microtubule binding ; GO:0008017 | inferred from direct assay microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity" "axo-dendritic transport ; GO:0008088 | inferred from mutant phenotype stress granule disassembly ; GO:0035617 | inferred from mutant phenotype mitochondrion distribution ; GO:0048311 | inferred from mutant phenotype maintenance of cell polarity ; GO:0030011 | inferred from mutant phenotype pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype microtubule sliding ; GO:0051012 | inferred from mutant phenotype oocyte dorsal/ventral axis specification ; GO:0007310 | inferred from mutant phenotype centrosome separation ; GO:0051299 | inferred from mutant phenotype regulation of pole plasm oskar mRNA localization ; GO:0007317 | inferred from mutant phenotype microtubule polymerization ; GO:0046785 | inferred from mutant phenotype larval locomotory behavior ; GO:0008345 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype heterochromatin organization involved in chromatin silencing ; GO:0070868 | inferred from mutant phenotype microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype microtubule-based movement ; GO:0007018 | inferred from direct assay transport along microtubule ; GO:0010970 | inferred from direct assay dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype pole plasm assembly ; GO:0007315 | inferred from mutant phenotype skeletal muscle fiber development ; GO:0048741 | inferred from mutant phenotype axonogenesis ; GO:0007409 | inferred from mutant phenotype intracellular distribution of mitochondria ; GO:0048312 | inferred from mutant phenotype pole plasm oskar mRNA localization ; GO:0045451 | non-traceable author statement intracellular protein transport ; GO:0006886 | inferred from mutant phenotype oocyte microtubule cytoskeleton polarization ; GO:0008103 | inferred from mutant phenotype eye photoreceptor cell differentiation ; GO:0001754 | inferred from genetic interaction with DCTN1-p150 mitochondrion transport along microtubule ; GO:0047497 | inferred from mutant phenotype actin filament bundle organization ; GO:0061572 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype establishment of nucleus localization ; GO:0040023 | inferred from mutant phenotype regulation of pole plasm oskar mRNA localization ; GO:0007317 | traceable author statement cytoplasmic transport, nurse cell to oocyte ; GO:0007303 | traceable author statement" actin cap ; GO:0030478 | inferred from direct assay mitochondrion ; GO:0005739 | colocalizes_with inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay kinesin complex ; GO:0005871 | inferred from sequence or structural similarity kinesin complex ; GO:0005871 | inferred from direct assay microtubule plus-end ; GO:0035371 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay microtubule ; GO:0005874 | "Khc, KHC, kinesin, khc, KIN, DK, DKH, CG7765, l(2)W12, DmKHC, l(2R)W12, Kin, l(2)k13314, Dmkin, kin, l(2)k13219, pgs, kinesin-1, Kinesin-1, DmK, KIF 5A, Kin-1, KIF5B, KIF5" "IPR001752:Kinesin motor domain, IPR019821:Kinesin motor domain, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG7765 27-Aug-18 DroID_v2018_08 "Drer\kif3b, Drer\kif5c, Drer\kif5aa, Drer\kif3a, Drer\kif5ba, Drer\LOC100333558, Drer\kif5bb, Drer\kif3cb, Drer\kif5ab" "Scer\KIP2, Scer\SMY1" "Cele\unc-116, Cele\ZC262.7" "Xtro\kif5a, Xtro\kif5b, Xtro\kif5c, Xtro\kif3c, Xtro\kif3b" "Mmus\Kif5a, Mmus\Kif3b, Mmus\Kif3c, Mmus\Kif5b, Mmus\Kif3a, Mmus\Kif5c" "Hsap\KIF5B, Hsap\KIF5A, Hsap\KIF3B, Hsap\KIF5C, Hsap\KIF3C" adult stage head

", oogenesis stage && adult stage | female , larval stage | third instar , oogenesis stage | stage S8-10A , adult stage && oogenesis stage , embryonic stage " " germarium && oogonial cell

, female germline stem cell

, egg chamber | early & oogonial cell

ubiquitous , photoreceptor cell | apical

, oocyte | posterior

, stage S8 oocyte | anterior & dorsal && stage S9 oocyte | anterior & dorsal && stage S10A oocyte | anterior & dorsal , nurse cell

, oocyte

,

ubiquitous , follicle cell

" "paralytic,short lived,flightless,developmental rate defective,locomotor behavior defective,neurophysiology defective,lethal - all die before end of larval stage,heat sensitive,some die during larval stage,lethal,recessive,neuroanatomy defective,some die during third instar larval stage,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of second instar larval stage,some die during second instar larval stage,mitotic cell cycle defective,cytokinesis defective,wild-type,partially lethal - majority die,behavior defective,visible,somatic clone,lethal - all die before end of embryonic stage,some die during embryonic stage,germline clone,body color defective,majority die during third instar larval stage,majority die during pupal stage" "eye,somatic clone,ommatidium,embryonic/larval neuromuscular junction | larval stage,dendrite,dorsal appendage,germline clone,maternal effect,embryonic/larval brain,microtubule,oocyte,microtubule | germline clone,mitochondrion,oocyte & nucleus | germ-line clone,lateral transverse muscle,eye photoreceptor cell,rhabdomere,eye photoreceptor cell & endoplasmic reticulum | somatic clone,eye photoreceptor cell & multivesicular body | somatic clone,macrochaeta,microchaeta,scutellar bristle,adult cuticle & scutellar bristle | somatic clone,embryo,stage S9 oocyte & nucleus | germ-line clone,pole plasm,pole plasm | germline clone,nurse cell fusome,mitochondrial cloud | germline clone,follicle cell & mitochondrion | germ-line clone,germline cyst & mitochondrion | germ-line clone,microtubule & oocyte | oogenesis stage S9 | germ-line clone,class IV dendritic arborizing neuron,axon,neuromuscular junction,embryonic/larval nervous system,posterior fascicle & axon,axonw+),axonwvco),oocyte nucleus,chorion | germline clone,trichogen cell,mesothoracic tergum,peripheral nervous system,mitochondrionrepo.PL, repo,embryonic/larval glial cell,embryonic/larval wrapping glial cell of the eye disc | third instar larval stage,embryonic/larval peripheral nervous system | third instar larval stage" FBgn0011760 ctp cut up http://flybase.org/reports/FBgn0011760 "FBgn0015619, FBgn0015650, FBgn0027256, FBgn0027271, FBgn0027293, FBgn0028265, FBgn0028273, FBgn0028298, FBgn0028309, FBgn0028322, FBgn0028337, FBgn0040189, FBgn0066852" protein_coding_gene "dynein light intermediate chain binding ; GO:0051959 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9V9Y9 protein homodimerization activity ; GO:0042803 | inferred from direct assay dynein intermediate chain binding ; GO:0045505 | inferred from physical interaction with sw ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with egg" sperm individualization ; GO:0007291 | inferred from mutant phenotype establishment of mitotic spindle orientation ; GO:0000132 | inferred from mutant phenotype spermatid nucleus elongation ; GO:0007290 | inferred from mutant phenotype microtubule anchoring at centrosome ; GO:0034454 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype chaeta development ; GO:0022416 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from mutant phenotype positive regulation of neuron remodeling ; GO:1904801 | inferred from mutant phenotype microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity salivary gland cell autophagic cell death ; GO:0035071 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype autophagy ; GO:0006914 | inferred from mutant phenotype chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype actin filament bundle assembly ; GO:0051017 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay cytoplasmic dynein complex ; GO:0005868 | inferred from direct assay centriole ; GO:0005814 | inferred from direct assay dynein complex ; GO:0030286 | inferred from direct assay dynein complex ; GO:0030286 | inferred from sequence or structural similarity "ddlc1, dlc, LC8, CG6998, Ddlc-1, Cdlc1, Ddlc1, l(1)G0153, l(1)G0207, l(1)G0204, l(1)G0248, l(1)G0338, l(1)G0387, l(1)G0371, l(1)G0432, l(1)G0445, l(1)G0244, Dlc, anon-WO03040301.128, ctp, Ctp, DLC8, lincRNA.S8635" "IPR001372:Dynein light chain, type 1/2, IPR019763:Dynein light chain, type 1/2, conserved site" CG6998 27-Aug-18 DroID_v2018_08 "Drer\dynll2a, Drer\dnal4a, Drer\dynll2b, Drer\dynll1, Drer\dnal4b" Scer\DYN2 "Cele\dlc-4, Cele\dlc-1, Cele\dlc-2, Cele\dlc-3, Cele\dlc-5" "Xtro\dynll2, Xtro\dnal4, Xtro\dynll1" "Mmus\Dynll2, Mmus\Dnal4, Mmus\Dynll1, Mmus\BC048507" "Hsap\DNAL4, Hsap\DYNLL1, Hsap\DYNLL2" " embryonic stage | late , adult stage && oogenesis stage | stage >S10 , adult stage && oogenesis stage , embryonic stage -- adult stage , pupal stage , adult stage , embryonic stage " " chordotonal organ

, oocyte

, nurse cell

, embryonic central nervous system

, head

,

ubiquitous " " embryonic stage , oogenesis stage "

ubiquitous "viable,female sterile,visible,behavior defective,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,heat sensitive,recessive,partially lethal - majority live,male sterile,male fertile,poor,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die,locomotor behavior defective,lethal - all die before end of pupal stage,some die during pupal stage,male semi-sterile,partially,wild-type,neuroanatomy defective,mitotic cell cycle defective,increased cell death" "scutum & macrochaeta,scutum & microchaeta,head & macrochaeta,macrochaeta,wing,wing vein,spermatid cyst,seminal vesicle,spermatozoon,spermatocyte fusome,wing & macrochaeta,ovariole,egg chamber,cystic bulge,actin filament bundle & nucleus,actin filament & spermatid,chaeta,salivary gland,lysosome | pupal stage,NMJ bouton,spermatid,nucleus & spermatid,scutum & macrochaeta & embryo,scutum & microchaeta & embryo,embryonic head & macrochaeta,leg & macrochaeta & embryo,sensory neuron,prothoracic femoral chordotonal organ & axon & pupa,longitudinal connective,commissure,prothoracic femoral chordotonal organ & axon,mesothoracic femoral chordotonal organ & axon,metathoracic femoral chordotonal organ & axon,astral microtubule,embryonic/larval neuroblast,astral microtubuleJC70),synaptonemal complex | somatic clone,somatic clone,ganglion mother cell,trichogen cell,tormogen cell,posterior compartment,wing disc" DRSC18758 IEK -2.163120436 -2.113667213 -1.500222659 -0.219841598 1.654270586 0.277847269 FBgn0022734 l(1)3Ai lethal (1) 3Ai http://flybase.org/reports/FBgn0022734 - gene - - - "l[4], l(1)3Ai" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" polytene chromosome FBgn0037001 ND-39 NADH dehydrogenase (ubiquinone) 39 kDa subunit http://flybase.org/reports/FBgn0037001 protein_coding_gene coenzyme binding ; GO:0050662 | inferred from electronic annotation with InterPro:IPR001509 NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:Q16795 NADH dehydrogenase activity ; GO:0003954 | inferred from biological aspect of ancestor with PANTHER:PTN000252522 "ubiquinone-6 biosynthetic process ; GO:1901006 | inferred from biological aspect of ancestor with PANTHER:PTN000252522 mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with UniProtKB:Q16795" mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:Q16795 "CG6020, GM13757p, NDUFA9, NUEM, ND-39, Ndufa9" "IPR001509:NAD-dependent epimerase/dehydratase, IPR016040:NAD(P)-binding domain" CG6020 27-Aug-18 DroID_v2018_08 Drer\ndufa9a - Cele\Y53G8AL.2 Xtro\ndufa9 Mmus\Ndufa9 Hsap\NDUFA9 "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0267548 lncRNA:CR45888 - http://flybase.org/reports/FBgn0267548 non_protein_coding_gene - - - CR45888 - CR45888 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0016884 l(2)39DEi lethal (2) 39DEi http://flybase.org/reports/FBgn0016884 - gene - - - "D241, l(2)39DEi" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0267294 lncRNA:CR45730 - http://flybase.org/reports/FBgn0267294 non_protein_coding_gene - - - CR45730 - CR45730 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032475 Sfmbt Scm-related gene containing four mbt domains http://flybase.org/reports/FBgn0032475 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012313 protein binding ; GO:0005515 | inferred from physical interaction with Scm methylated histone binding ; GO:0035064 | inferred from direct assay chromatin binding ; GO:0003682 | inferred from direct assay chromatin silencing ; GO:0006342 | inferred from direct assay imaginal disc growth ; GO:0007446 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype negative regulation of gene expression ; GO:0010629 | inferred from mutant phenotype chromatin silencing ; GO:0006342 | inferred from genetic interaction with Scm PcG protein complex ; GO:0031519 | inferred from physical interaction with pho nucleus ; GO:0005634 | inferred from direct assay "Sfmbt, SFMBT, dSfmbt, CG16975, dSFMBT" "IPR001660:Sterile alpha motif domain, IPR004092:Mbt repeat, IPR012313:Zinc finger, FCS-type, IPR013761:Sterile alpha motif/pointed domain" CG16975 27-Aug-18 DroID_v2018_08 "Drer\mbtd1, Drer\l3mbtl2" - "Cele\lin-61, Cele\mbtr-1" Xtro\mbtd1 "Mmus\Mbtd1, Mmus\L3mbtl2" "Hsap\MBTD1, Hsap\L3MBTL2" "tumorigenic,lethal - all die before end of larval stage,some die during third instar larval stage,lethal" "imaginal disc,female germline stem cell" FBgn0024555 flfl falafel http://flybase.org/reports/FBgn0024555 FBgn0038169 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with mira phagocytosis ; GO:0006909 | inferred from mutant phenotype neuroblast proliferation ; GO:0007405 | inferred from mutant phenotype DNA repair ; GO:0006281 | inferred from mutant phenotype asymmetric neuroblast division ; GO:0055059 | inferred from mutant phenotype asymmetric protein localization ; GO:0008105 | inferred from mutant phenotype "protein phosphatase 4 complex ; GO:0030289 | inferred from direct assay chromosome, centromeric region ; GO:0000775 | inferred from physical interaction with Cenp-C nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay CENP-A containing nucleosome ; GO:0043505 | colocalizes_with inferred from direct assay" "CG9351, l(3)L4179, flfl, PP4R3, Ppp4R3, Flfl" "IPR006887:Domain of unknown function DUF625, IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical, IPR011993:PH domain-like" CG9351 27-Aug-18 DroID_v2018_08 "Drer\ppp4r3b, Drer\smek1" Scer\PSY2 Cele\smk-1 "Xtro\ppp4r3b, Xtro\ppp4r3a" "Mmus\Smek1, Mmus\4930415L06Rik, Mmus\Smek2, Mmus\4932429P05Rik" "Hsap\PPP4R3A, Hsap\PPP4R3B" "viable,fertile,lethal,recessive,female fertile,poor,visible,partially lethal - majority die,some die during pupal stage,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of larval stage,some die during third instar larval stage,decreased cell number,some die during larval stage,cell cycle defective" "wing,wing vein,mesothoracic tergum,neuroblast,cell" DRSC16474 IE -0.95830043 -2.070318391 -0.746483781 -3.562944432 0.019560106 0.750596516 FBgn0040080 pins partner of inscuteable http://flybase.org/reports/FBgn0040080 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P20353 protein binding ; GO:0005515 | inferred from physical interaction with Gαi inferred from physical interaction with mud GDP-dissociation inhibitor activity ; GO:0005092 | inferred from direct assay protein domain specific binding ; GO:0019904 | inferred from physical interaction with cno regulation of G-protein coupled receptor protein signaling pathway ; GO:0008277 | inferred from electronic annotation with InterPro:IPR024804 asymmetric cell division ; GO:0008356 | inferred from direct assay establishment of mitotic spindle orientation ; GO:0000132 | inferred from mutant phenotype asymmetric protein localization involved in cell fate determination ; GO:0045167 | traceable author statement asymmetric cell division ; GO:0008356 | inferred from mutant phenotype asymmetric neuroblast division ; GO:0055059 | inferred from mutant phenotype maintenance of protein location ; GO:0045185 | non-traceable author statement basal protein localization ; GO:0045175 | traceable author statement neuroblast fate determination ; GO:0007400 | traceable author statement establishment of spindle orientation ; GO:0051294 | inferred from mutant phenotype asymmetric cell division ; GO:0008356 | traceable author statement asymmetric protein localization ; GO:0008105 | traceable author statement establishment of mitotic spindle localization ; GO:0040001 | traceable author statement neuroblast proliferation ; GO:0007405 | inferred from mutant phenotype establishment of mitotic spindle orientation ; GO:0000132 | inferred from direct assay apical cortex ; GO:0045179 | traceable author statement apical cortex ; GO:0045179 | inferred from direct assay cell cortex ; GO:0005938 | traceable author statement cell cortex ; GO:0005938 | inferred from direct assay apical part of cell ; GO:0045177 | non-traceable author statement "pins, Pins, PINS, CG5692, rapsyn, rad, Rad, raps, Raps" "IPR003109:GoLoco motif, IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat, IPR024804:G-protein-signalling modulator 1" CG5692 27-Aug-18 DroID_v2018_08 "Drer\ogt.1, Drer\gpsm2, Drer\LOC558761, Drer\gpsm1a, Drer\gpsm2l, Drer\gpsm1b" - Cele\ags-3 "Xtro\ttc28, Xtro\gpsm2, Xtro\gpsm1" "Mmus\Ttc24, Mmus\Pcp2, Mmus\Gpsm2, Mmus\Gpsm1, Mmus\Gpsm3" "Hsap\GPSM3, Hsap\PCP2, Hsap\TTC28, Hsap\GPSM1, Hsap\GPSM2" embryonic stage " neuroblast

, mitotic domain 9

" "viable,visible,mitotic cell cycle defective,neuroanatomy defective,cell polarity defective,tumorigenic,cell cycle defective,lethal - all die before end of pupal stage,recessive,some die during pupal stage" "ganglion mother cell GMC4-2a,tormogen cell,mitotic domain 9 & spindle,RP2 motor neuron,ectopic,RP2sib neuron,neuroblast,mitotic cell cycle & spindle,embryonic neuroblast & spindle,centrosome,larval brain & neuroblast,mitotic domain 9 & epithelial cell,spindle,aster,spindle & larval neuroblast,embryonic/larval neuroblast,spindle & external sensory organ precursor cell I,embryonic neuroblast,wing margin,intersegmental nerve,anterior fascicle & synapse,anterior fascicle & synapse | supernumerary" FBgn0024662 l(2)k06501 lethal (2) k06501 http://flybase.org/reports/FBgn0024662 - gene - - - "65/1, l(2)k06501" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" imaginal disc FBgn0261430 CR42647 - http://flybase.org/reports/FBgn0261430 non_protein_coding_gene - - - "CR42647, CR41487" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0022304 l(1)L48.3 lethal (1) L48.3 http://flybase.org/reports/FBgn0022304 - gene - - - "L48.3, l(1)L48.3" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0053286 CG33286 - http://flybase.org/reports/FBgn0053286 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG12982, CG33286" "IPR022110:Casc1 domain, IPR031826:Cancer susceptibility candidate 1, N-terminal" CG33286 27-Aug-18 DroID_v2018_08 Drer\casc1 - Cele\K09E2.2 - Mmus\Casc1 Hsap\CASC1 viable DRSC26119 K 0.267726939 0.083941492 0.491397888 0.335642288 2.721093434 1.641308951 FBgn0014919 anon-72ABc anon-72ABc http://flybase.org/reports/FBgn0014919 - gene - - - anon-72ABc - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0015317 U2af35 U2 small nuclear riboprotein auxiliary factor 35 http://flybase.org/reports/FBgn0015317 FBgn0012029 gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred from direct assay" nucleoplasm ; GO:0005654 | inferred from direct assay "U2AF-35kDa, U2AF, U2AF[35], U2af35" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030102 SmydA-9 "SET and MYND domain containing, arthropod-specific, member 9" http://flybase.org/reports/FBgn0030102 protein_coding_gene histone deacetylase binding ; GO:0042826 | inferred from sequence or structural similarity with Smyd4-2 negative regulation of gene expression ; GO:0010629 | inferred from sequence or structural similarity with Smyd4-2 nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "lincRNA.971, SmydA-9, CG12119" IPR001214:SET domain CG12119 27-Aug-18 DroID_v2018_08 "Drer\smyd1b, Drer\smyd4, Drer\smyd1a, Drer\smyd3, Drer\smyd2b, Drer\smyd2a" "Scer\SET5, Scer\SET6" "Cele\set-10, Cele\set-18, Cele\set-14" "Xtro\smyd4, Xtro\smyd1, Xtro\smyd5" "Mmus\Smyd2, Mmus\Smyd5, Mmus\Smyd3, Mmus\Smyd1, Mmus\Smyd4" "Hsap\SMYD2, Hsap\SMYD4, Hsap\SMYD3, Hsap\SMYD5, Hsap\SMYD1" "viable,fertile" FBgn0016977 spen split ends http://flybase.org/reports/FBgn0016977 "FBgn0010537, FBgn0016056, FBgn0016624, FBgn0022059, FBgn0022080, FBgn0022115, FBgn0026182, FBgn0031230, FBgn0040065, FBgn0047291, FBtr0078121, FBpp0077780, FBtr0078122, FBpp0077781, FBtr0078123, FBpp0077782" protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from biological aspect of ancestor with PANTHER:PTN000573351 "transcription, DNA-templated ; GO:0006351 | inferred from mutant phenotype segment specification ; GO:0007379 | inferred from mutant phenotype establishment of thoracic bristle planar orientation ; GO:0048106 | inferred from mutant phenotype imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype defense response to fungus ; GO:0050832 | inferred from mutant phenotype wing disc pattern formation ; GO:0035222 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from expression pattern epidermal growth factor receptor signaling pathway ; GO:0007173 | inferred from mutant phenotype maintenance of imaginal disc-derived wing hair orientation ; GO:0035321 | inferred from mutant phenotype Wnt signaling pathway ; GO:0016055 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from biological aspect of ancestor with PANTHER:PTN000573351 glial cell fate determination ; GO:0007403 | inferred from mutant phenotype positive regulation of Wnt signaling pathway ; GO:0030177 | inferred from genetic interaction with arm inferred from genetic interaction with hid inferred from genetic interaction with wg neuroblast fate determination ; GO:0007400 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "Splitends, CG18497, rno, EK2-9, E(Sev-CycE)2A, EY2-7, spe, E(E2F)2A, l(2)k08102, l(2)k07612, l(2)k06805, l(2)03350, poc, 136/24, yip1, En(yan[ACT])2-7, E(Raf)2A, BcDNA:GM01870, spen, SPEN, Spen" "IPR000504:RNA recognition motif domain, IPR010912:Spen paralogue/orthologue C-terminal, metazoa, IPR012921:Spen paralogue and orthologue SPOC, C-terminal, IPR016194:SPOC-like, C-terminal domain, IPR034174:SHARP, RNA recognition motif 3, IPR015943:WD40/YVTN repeat-like-containing domain, IPR034175:SHARP, RNA recognition motif 4, IPR034173:SHARP, RNA recognition motif 2" CG18497 27-Aug-18 DroID_v2018_08 "Drer\spen, Drer\rbm15b, Drer\wu:fb69f10, Drer\rbm15" "Scer\MRN1, Scer\NRD1" "Cele\din-1, Cele\cec-8" "Xtro\rbm15, Xtro\rbm15b" "Mmus\Spen, Mmus\Rbm15b, Mmus\Rbm15" "Hsap\RBM15B, Hsap\RBM15, Hsap\SPEN" " embryonic stage | 0-24 hr , embryonic stage , embryonic stage | 2-24 hr " " embryonic stage | stage 9-14 , embryonic stage , embryonic stage | stage >=3 , larval stage " " embryonic central nervous system

, embryonic epidermis

, organism

, eye disc

, ventral thoracic disc

, dorsal mesothoracic disc

" "lethal,recessive,immune response defective,wound healing defective,viable,fertile,visible,neuroanatomy defective,cell polarity defective,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage" "ommatidium,eye photoreceptor cell,hemocyte,plasmatocyte,crystal cell,macrochaeta,scutellar bristle,ectopic,dorsocentral bristle,tormogen cell,embryonic/larval central nervous system,neurite | pharate adult stage,midline glial cell,commissure,longitudinal connective,central nervous system,presumptive embryonic/larval peripheral nervous system,germline clone,presumptive embryonic/larval central nervous system,abdominal lateral pentascolopidial chordotonal organ lch5,intersegmental nerve,transverse nerve,abdominal segmental nerve,wing vein,somatic clone,crossvein,wing hair,wing margin bristle,microchaeta,head & cuticle | ectopic,embryonic thorax,embryonic thorax & cuticle,embryonic head,hypostomal sclerite,lch5 neuron,ventral midline,ventral nerve cord commissure,motor neuron,embryonic/larval somatic muscle,sclerite,embryonic mesothoracic segment & sclerite | ectopic,embryonic metathoracic segment & sclerite | ectopic,sclerite & embryonic abdominal segment | ectopic,mouth hooks,median tooth,dental sclerite,epipharyngeal sclerite,dorsal bridge,lateral process,embryonic epidermis,sclerite & embryonic head,chordotonal organ & axon | lateral,ventral thoracic disc,denticle belt,embryonic/first instar larval cuticle,eye,mesothoracic tergum,trichogen cell" FBgn0001079 fu fused http://flybase.org/reports/FBgn0001079 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with cos protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity" "protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR008271 smoothened signaling pathway ; GO:0007224 | traceable author statement smoothened signaling pathway ; GO:0007224 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype regulation of protein stability ; GO:0031647 | inferred from direct assay positive regulation of hh target transcription factor activity ; GO:0007228 | inferred from mutant phenotype inferred from genetic interaction with hh positive regulation of protein ubiquitination ; GO:0031398 | inferred from mutant phenotype regulation of proteolysis ; GO:0030162 | non-traceable author statement positive regulation of transcription factor import into nucleus ; GO:0042993 | inferred from mutant phenotype segment polarity determination ; GO:0007367 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | non-traceable author statement intraciliary transport ; GO:0042073 | inferred from mutant phenotype negative regulation of BMP signaling pathway ; GO:0030514 | inferred from genetic interaction with tkv inferred from genetic interaction with Dad protein phosphorylation ; GO:0006468 | non-traceable author statement" membrane ; GO:0016020 | inferred from direct assay protein complex ; GO:0043234 | inferred from physical interaction with Su(fu) Hedgehog signaling complex ; GO:0035301 | inferred from physical interaction with cos inferred from physical interaction with ci "fu, Fu, CG6551, fu[mel], Dm fu, l(1)fu, FU, dFu" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG6551 27-Aug-18 DroID_v2018_08 "Drer\stk36, Drer\ulk4" Scer\ATG1 Cele\F32D8.1 "Xtro\ulk4, Xtro\stk36" "Mmus\Ulk4, Mmus\Stk36" "Hsap\STK36, Hsap\ULK4" " adult stage , adult stage | female , embryonic stage | <= stage 11 , embryonic stage | early , larval stage " " egg chamber | subset

, organism

,

ubiquitous , germarium region 2

, imaginal disc

" adult stage " germarium region 2

, egg chamber | subset

" "visible,recessive,viable,female fertile,reduced,wild-type,tumorigenic,lethal,rescuable maternal effect,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage,female semi-sterile,germline clone,lethal - all die before end of P-stage,some die during pharate adult stage,female sterile,somatic clone,segment polarity phenotype,hyperplasia,heat sensitive" "wing,anterior compartment,sensillum campaniformium,ectopic,wing vein,1st posterior cell,double row,wing vein L3,wing vein L4,wing basal cell 2,dil cell,egg,germline clone,embryo,ovary,denticle belt,maternal effect,embryonic ventral nervous system,blastoderm embryo,embryonic segment,proximal,Bolwig organ,germline cell,cell non-autonomous,somatic clone,posterior compartment,oocyte,egg chamber,cystoblast,supernumerary,ocellar bristle,interocellar bristle,lateral ocellus,medial ocellus,ovariole,distal,microchaeta & tarsal segment 1,microchaeta & tarsal segment 2,microchaeta & tarsal segment 3,microchaeta & tarsal segment 4,microchaeta & tarsal segment 5,macrochaeta & tarsal segment 5 | distal,mesothoracic tarsal bristle longitudinal row 4,mesothoracic tarsal bristle longitudinal row 3.5,mesothoracic tarsal bristle longitudinal row 1,mesothoracic tarsal bristle longitudinal row 5,mesothoracic tarsal bristle longitudinal row 8,mesothoracic tarsal bristle longitudinal row 2.5,wing sensillum,dorsal double row,ventral double row,sensillum campaniformium of dorsal radius,anterior crossvein,embryonic epidermis,ocellus,anterior scutellar bristle,scutellum,embryonic thorax,embryonic abdomen,interfollicle cell,polar follicle cell,nurse cell,presumptive embryonic/larval central nervous system,posterior cell,wing basal cell 1,posterior scutellar bristle,dorsal hair,segment,posterior,germarium,female germline cell" DRSC20333 I 0.490788449 -2.434819276 0.442541585 0.657667334 -0.476184012 0.097666183 FBgn0001965 Sos Son of sevenless http://flybase.org/reports/FBgn0001965 "FBgn0013235, FBgn0026802" protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR007125 protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 protein binding ; GO:0005515 | inferred from physical interaction with drk Ras guanyl-nucleotide exchange factor activity ; GO:0005088 | inferred from sequence or structural similarity Ras guanyl-nucleotide exchange factor activity ; GO:0005088 | inferred from direct assay Rac guanyl-nucleotide exchange factor activity ; GO:0030676 | inferred from genetic interaction with Rac1 "regulation of Rho protein signal transduction ; GO:0035023 | inferred from electronic annotation with InterPro:IPR000219 negative regulation of G1/S transition of mitotic cell cycle ; GO:2000134 | inferred from mutant phenotype imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype tracheal outgrowth, open tracheal system ; GO:0007426 | inferred from mutant phenotype axon midline choice point recognition ; GO:0016199 | inferred from genetic interaction with robo1, Rac1, RhoGAP93B, sli torso signaling pathway ; GO:0008293 | traceable author statement positive regulation of Ras protein signal transduction ; GO:0046579 | inferred by curator from GO:0005088 positive regulation of Rac protein signal transduction ; GO:0035022 | inferred from genetic interaction with Rac1 regulation of cell shape ; GO:0008360 | inferred from mutant phenotype anterior/posterior axis specification, embryo ; GO:0008595 | traceable author statement sevenless signaling pathway ; GO:0045500 | traceable author statement actin filament organization ; GO:0007015 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay extrinsic component of cytoplasmic side of plasma membrane ; GO:0031234 | inferred from direct assay "sos, EK2-8, Su(tor)2-2, E(sev)2A, 34Ea, br25, l(2)br24, Sos1, EY2-3, BG:DS00941.4, l(2)34Ea, dSos, l(2)k05224, 2.3, l(2)k06321, dme-SOS, SOS, br24, l(2)br25, l(2)Sos, E(var)189, CG7793, Sos, EC2-5" "IPR000219:Dbl homology (DH) domain, IPR000651:Ras-like guanine nucleotide exchange factor, N-terminal, IPR001849:Pleckstrin homology domain, IPR001895:Ras guanine-nucleotide exchange factors catalytic domain, IPR007125:Histone H2A/H2B/H3, IPR011993:PH domain-like, IPR009072:Histone-fold, IPR019804:Ras guanine-nucleotide exchange factor, conserved site, IPR023578:Ras guanine nucleotide exchange factor domain" CG7793 27-Aug-18 DroID_v2018_08 "Drer\rasgrf2a, Drer\rapgef1a, Drer\si:ch211-234p18.3, Drer\sos2, Drer\LOC797658, Drer\rasgrf2b, Drer\sos1, Drer\rapgef1b" "Scer\BUD5, Scer\LTE1, Scer\CDC25, Scer\YCL068C" "Cele\pxf-1, Cele\sos-1, Cele\Y34B4A.4" "Xtro\rapgef1, Xtro\sos1, Xtro\sos2" "Mmus\Sos2, Mmus\Rapgef6, Mmus\Rasgrf1, Mmus\Sos1, Mmus\Rapgef2, Mmus\Rasgrp2, Mmus\Ralgps2, Mmus\Rasgef1b, Mmus\Rapgef1, Mmus\Rasgrf2" "Hsap\RASGRF2, Hsap\RAPGEF1, Hsap\RASGRP2, Hsap\RASGEF1B, Hsap\SOS2, Hsap\RASGRF1, Hsap\SOS1, Hsap\RAPGEF2" "visible,viable,fertile,recessive,lethal,enhancer of variegation,dominant,wild-type,mitotic cell cycle defective,cell autonomous,somatic clone,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage,neuroanatomy defective,terminal phenotype,germline clone,maternal effect,body color defective" "wing,wing vein,photoreceptor cell R7,ommatidium,somatic clone,dorsal air sac primordium,pCC neuron,dMP2 neuron,vMP2 neuron,longitudinal connective,eye,ectopic,macrochaeta,commissure,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,photoreceptor cell R8,eye disc,cell autonomous,midline crossing tract,embryo,germline clone,maternal effect,wing vein L4,abdominal 1 ventral monoscolopidial chordotonal organ vch1,abdominal 2 ventral monoscolopidial chordotonal organ vch1,abdominal 3 ventral monoscolopidial chordotonal organ vch1,abdominal 4 ventral monoscolopidial chordotonal organ vch1,abdominal 5 ventral monoscolopidial chordotonal organ vch1,abdominal 6 ventral monoscolopidial chordotonal organ vch1,abdominal 7 ventral monoscolopidial chordotonal organ vch1,abdominal 1 lateral pentascolopidial chordotonal organ lch5,abdominal 2 lateral pentascolopidial chordotonal organ lch5,abdominal 3 lateral pentascolopidial chordotonal organ lch5,abdominal 4 lateral pentascolopidial chordotonal organ lch5,abdominal 5 lateral pentascolopidial chordotonal organ lch5,abdominal 6 lateral pentascolopidial chordotonal organ lch5,abdominal 7 lateral pentascolopidial chordotonal organ lch5,chaeta,supernumerary,trichogen cell,mesothoracic tergum" DRSC03439 IEK -2.867508031 -6.526072224 -3.167020634 -3.67134216 -1.435347178 -2.484029732 FBgn0001033 Fs(3)Dam Female sterile (3) Damasa http://flybase.org/reports/FBgn0001033 - gene - embryo development ending in birth or egg hatching ; GO:0009792 | inferred from mutant phenotype - "Dam, Fs(3)Damasa, Fs(3)Sz7, Fs(3)Dam" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" FBgn0264364 CG43816 - http://flybase.org/reports/FBgn0264364 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43816 - CG43816 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0028994 saguaro saguaro http://flybase.org/reports/FBgn0028994 gene - dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype - saguaro - - 27-Aug-18 DroID_v2018_08 - - - - - - dendrite | dorsal | embryonic stage FBgn0266228 lncRNA:CR44923 - http://flybase.org/reports/FBgn0266228 non_protein_coding_gene - - - "CR44923, lincRNA.672" - CR44923 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259941 ttd5 TRPL translocation defect 5 http://flybase.org/reports/FBgn0259941 protein_coding_gene - - - ttd5 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002999 omm ommatoreductum http://flybase.org/reports/FBgn0002999 - gene - - - omm - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile,visible,recessive" "ommatidium,eye,adult head,head bristle,maxillary palpus,macrochaeta & adult thorax,wing" FBgn0260271 GSd466 - http://flybase.org/reports/FBgn0260271 gene - - - GSd466 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0024353 H217 H217 http://flybase.org/reports/FBgn0024353 - gene - - - H217 - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,neuroanatomy defective,recessive" "optic lobe,medulla neuropil,medulla,proximal,lamina,distal,lobula plate" FBgn0010341 Cdc42 Cdc42 http://flybase.org/reports/FBgn0010341 FBgn0012059 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003578, InterPro:IPR005225 protein binding ; GO:0005515 | inferred from physical interaction with Whamy protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9W1B0 GTPase activity ; GO:0003924 | non-traceable author statement protein kinase binding ; GO:0019901 | inferred from physical interaction with mbt protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VXE5 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity GTPase activity ; GO:0003924 | inferred from direct assay GTPase activating protein binding ; GO:0032794 | inferred from physical interaction with RacGAP84C GTPase activity ; GO:0003924 | traceable author statement protein kinase binding ; GO:0019901 | inferred from physical interaction with Pak3" "positive regulation of wound healing=0090303 |... mutant phenotype <> maintenance of protein location=0045185 |... mutant phenotype <> protein localization to plasma membrane=0072659 |... mutant phenotype <> Rho protein signal transduction=0007266 |... genetic interaction with Zir <> branching involved in open tracheal system development=0060446 |... mutant phenotype <> dendrite morphogenesis=0048813 |... mutant phenotype <> actin filament polymerization=0030041 |... mutant phenotype <> JNK cascade=0007254 | traceable author statement <> regulation of actin filament polymerization=0030833 |... mutant phenotype <> encapsulation of foreign target=0035010 |... mutant phenotype <> axon guidance=0007411 |... mutant phenotype <> actin filament polymerization=0030041 | traceable author statement <> dorsal closure=0007391 | traceable author statement <> establishment of neuroblast polarity=0045200 |... mutant phenotype <> phagocytosis=0006909 |... mutant phenotype <> maintenance of cell polarity=0030011 |... mutant phenotype <> melanotic encapsulation of foreign target=0035011 |... mutant phenotype <> axonogenesis=0007409 | traceable author statement <> regulation of cell shape=0008360 |... mutant phenotype <> actin filament organization=0007015 |... mutant phenotype <> nephrocyte filtration=0097206 |... mutant phenotype <> regulation of glucose metabolic process=0010906 |... mutant phenotype <> wound healing=0042060 |... mutant phenotype <> cellularization=0007349 | traceable author statement <> dorsal closure=0007391 |... mutant phenotype <> positive regulation of protein kinase activity=0045860 |... mutant phenotype <> transforming growth factor beta receptor signaling pathway=0007179 | traceable author statement <> neuron projection morphogenesis=0048812 |... mutant phenotype <> dorsal closure, amnioserosa morphology change=0046664 | NOT inferred from mutant phenotype <> germarium-derived egg chamber formation=0007293 |... mutant phenotype <> suture of dorsal opening=0007396 | traceable author statement <> epithelium development=0060429 |... mutant phenotype <> actin cytoskeleton reorganization=0031532 |... mutant phenotype <> cortical actin cytoskeleton organization=0030866 |... mutant phenotype <> regulation of actin filament polymerization=0030833 |... direct assay <> sensory perception of touch=0050975 |... mutant phenotype <> oogenesis=0048477 | traceable author statement <> cytoskeleton organization=0007010 | non-traceable author statement <> axon extension=0048675 |... genetic interaction with Frl <> cell projection assembly=0030031 |... mutant phenotype <> ovarian follicle cell development=0030707 | traceable author statement <> positive regulation of lamellipodium assembly=0010592 |... mutant phenotype <> spermatid development=0007286 |... mutant phenotype <> regulation of synaptic growth at neuromuscular junction=0008582 |... direct assay <> positive regulation of filopodium assembly=0051491 |... mutant phenotype <> neuromuscular synaptic transmission=0007274 |... genetic interaction with cv-c inferred from genetic interaction with Dys <> regulation of synaptic growth at neuromuscular junction=0008582 |... mutant phenotype <> vesicle-mediated transport=0016192 |... mutant phenotype <> dorsal appendage formation=0046843 |... mutant phenotype <> imaginal disc-derived wing hair outgrowth=0035318 |... mutant phenotype <> motor neuron axon guidance=0008045 |... mutant phenotype <> hemocyte migration=0035099 |... mutant phenotype <> actin cytoskeleton organization=0030036 | traceable author statement <> regulation of axonogenesis=0050770 |... genetic interaction with LIMK1 <> exocyst localization=0051601 |... mutant phenotype <> neuron projection development=0031175 |... mutant phenotype" rhabdomere ; GO:0016028 | inferred from mutant phenotype axon ; GO:0030424 | inferred from direct assay adherens junction ; GO:0005912 | inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay growth cone ; GO:0030426 | inferred from direct assay apical part of cell ; GO:0045177 | inferred from direct assay "DmCDC42, cdc42, Dcdc42, Dm Cdc42, DCdc42, CDC42, DCDC42, Cdc42Dm, D-CDC42, D-Cdc42, Dmcdc42, CG12530, Cdc42, D-cdc42, P40793" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR003578:Small GTPase superfamily, Rho type, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG12530 27-Aug-18 DroID_v2018_08 "Drer\rac3b, Drer\rhogd, Drer\rhoac, Drer\rhoab, Drer\cdc42l2, Drer\rnd3a, Drer\rhogc, Drer\rhobtb2a, Drer\LOC100331257, Drer\rhoq, Drer\rac1b, Drer\rac1a, Drer\cdc42, Drer\rhoj, Drer\rhof, Drer\rhoh, Drer\rhobtb2b, Drer\si:dkey-263f15.2, Drer\rhobtb1, Drer\rnd3b, Drer\rac3a, Drer\rnd1a, Drer\rnd2, Drer\rhoub, Drer\si:dkey-6b12.5, Drer\cdc42l, Drer\rhoca, Drer\si:ch211-133l11.10, Drer\rhogb, Drer\LOC100537765, Drer\rhov, Drer\rhocb, Drer\rhoga, Drer\rac1l, Drer\rhoua, Drer\rhoaa, Drer\rnd1b" "Scer\RHO2, Scer\RHO4, Scer\RHO3, Scer\RHO1, Scer\CDC42, Scer\RHO5" "Cele\crp-1, Cele\mig-2, Cele\ced-10, Cele\cdc-42" "Xtro\rhoa, Xtro\rhoa.2, Xtro\rhof, Xtro\rnd3, Xtro\rhobtb2, Xtro\rac2, Xtro\rhobtb1, Xtro\rnd1, Xtro\rhou, Xtro\rac1, Xtro\cdc42, Xtro\rhoj, Xtro\rhoc, Xtro\rhob, Xtro\rhov, Xtro\rhobtb3" "Mmus\Rac1, Mmus\4930544G11Rik, Mmus\Rac3, Mmus\Rhof, Mmus\Rhob, Mmus\Rhoh, Mmus\Rhoj, Mmus\Rhobtb2, Mmus\Rnd2, Mmus\Rhoc, Mmus\Rhobtb1, Mmus\Rhog, Mmus\Rnd3, Mmus\Rhod, Mmus\Rhou, Mmus\Rnd1, Mmus\Rhobtb3, Mmus\Rhov, Mmus\Rhoa, Mmus\Cdc42, Mmus\Rhoq, Mmus\Rac2" "Hsap\RHOC, Hsap\RND3, Hsap\RHOJ, Hsap\RND1, Hsap\RHOBTB1, Hsap\RHOH, Hsap\CDC42, Hsap\RAC2, Hsap\RHOD, Hsap\RHOU, Hsap\RHOBTB3, Hsap\RHOQ, Hsap\RHOB, Hsap\RHOBTB2, Hsap\RHOG, Hsap\RAC1, Hsap\RHOA, Hsap\RAC3, Hsap\RHOV, Hsap\RND2, Hsap\RHOF" " embryonic stage | stage 10-12 , embryonic stage , embryonic stage | blastoderm , embryonic stage -- adult stage " " somatic mesoderm

, embryonic central nervous system

, embryonic/larval digestive system

,

ubiquitous " "male sterile,wild-type,visible,lethal,recessive,cell shape defective,planar polarity defective,somatic clone,wound healing defective,lethal - all die before end of embryonic stage,maternal effect,partially,some die during embryonic stage,neuroanatomy defective,cell polarity defective,decreased cell size,viable,size defective,immune response defective,non-rescuable maternal effect,lethal - all die before end of pupal stage,some die during pupal stage,touch sensitivity defective,lethal - all die before end of larval stage,some die during larval stage,heat sensitive,female,partially lethal - majority die,neurophysiology defective,chemical sensitive,chemical resistant" "spermatid cyst,seminal vesicle,head cyst cell,actin filamentT155,nurse cell,eye,ommatidium,photoreceptor,pigment cell,rhabdomere,interommatidial bristle,anterior crossvein,ectopic,follicle cell,somatic clone,wing,crossvein,embryo,maternal effect,nurse cell ring canal,germline clone,actin filament | germline clone | maternal effect,vertical system neuron,oocyte,dendrite | ectopic,dendritic spine,axon,terminal tracheal cell,eye photoreceptor cell,retina,embryonic/larval pericardial cell,dorsal closure embryo,embryonic epidermis,ventral,embryonic/first instar larval cuticle,anterior,presumptive embryonic/larval central nervous system,longitudinal connective,embryonic hemocyte,macrophage,nurse cell & actin filament | germ-line clone | maternal effect,proventriculus inner layer primordium,proventriculus intermediate layer primordium,embryonic proventriculus,ganglionic branch primordium,neuroblast,wing hair,supernumerary,actin filament & rhabdomere | somatic clone,neuromuscular junction,bouton,embryonic/larval neuromuscular junction,NMJ bouton,microchaeta & wingptc-559.1,wing disc,anterior/posterior compartment boundary,dorsal,embryonic hemocyte & leading edgePxn.PS, crq.PA,embryonic/larval dorsal trunk,embryonic/larval somatic muscle,myotube,muscle attachment site,microchaeta,wing vein,wing margin,wing margin bristle,heat sensitive,medial triple row,cell non-autonomous,presumptive embryonic/larval tracheal system,antenna & glial cellMz317,antenna & sensory neuronMz317,embryonic/larval midgut | embryonic stage,dorsal appendage,abdominal segmental nerve,neuroblast | embryonic stage,neuromuscular junctionMhc.Switch.PO,dorsal multidendritic neuron ddaA | larval stage,sensory dendrite | larval stage1003.3,neuron,abdominal posterior fascicle neuron & growth cone & filopodiumelav.PLu,mesothoracic les3 neuron & growth cone & filopodiumelav.PLu,metathoracic les3 neuron & growth cone & filopodiumelav.PLu,dendrite | dorsal | embryonic stage60,presumptive embryonic/larval peripheral nervous system,dorsal multidendritic neuron | embryonic stage,dorsal multidendritic neuron & dendrite & embryo60,abdominal intersegmental nerve,dorsal abdominal cluster,dendrite,somatic muscle,antennal commissure,antennal lobe glomerulus,glomerulus,mesothoracic leg disc,aCC neuron & dendriteeve.RN2,RP2 neuron & dendriteeve.RN2,RP2 motor neuron,RP2 neuron & neuriteeve.RN2,RP2 neuron & cell bodyeve.RN2,pCC neuron,dMP2 neuron,vMP2 neuron,midline crossing tract | embryonic stage 16,ventral nerve cord commissure | embryonic stage 16,macrochaeta & metathoracic laterotergiteBx-MS1096,microchaeta & metathoracic laterotergiteBx-MS1096,motor neuron,growth coneelav.PLu,tergal depressor of trochanter muscle motor neuron & dendriteshakB.lethal.4.1,giant fiber neuron,eye disc,growth cone,neurite,giant axon,anterior embryonic/larval midgut,aCC neuron,neuromuscular junctionC57,epithelium,female germline cyst" FBgn0260442 rhea rhea http://flybase.org/reports/FBgn0260442 protein_coding_gene actin filament binding ; GO:0051015 | inferred from electronic annotation with InterPro:IPR006077 structural constituent of cytoskeleton ; GO:0005200 | inferred from electronic annotation with InterPro:IPR015224 insulin receptor binding ; GO:0005158 | inferred from electronic annotation with InterPro:IPR002404 protein binding ; GO:0005515 | inferred from physical interaction with wech actin binding ; GO:0003779 | inferred from sequence or structural similarity integrin binding ; GO:0005178 | inferred from physical interaction with mys "cytoskeletal anchoring at plasma membrane ; GO:0007016 | inferred from electronic annotation with InterPro:IPR015224 cytoskeletal anchoring at plasma membrane ; GO:0007016 | inferred from sequence or structural similarity muscle attachment ; GO:0016203 | inferred from mutant phenotype cardiac muscle cell-cardiac muscle cell adhesion ; GO:0086042 | inferred from mutant phenotype sarcomere organization ; GO:0045214 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | inferred from mutant phenotype cell adhesion ; GO:0007155 | traceable author statement germ-band shortening ; GO:0007390 | inferred from mutant phenotype cell adhesion mediated by integrin ; GO:0033627 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype larval somatic muscle development ; GO:0007526 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype cell adhesion ; GO:0007155 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from mutant phenotype maintenance of epithelial integrity, open tracheal system ; GO:0035160 | inferred from mutant phenotype" cytoskeleton ; GO:0005856 | inferred from electronic annotation with InterPro:IPR000299 ruffle ; GO:0001726 | inferred from electronic annotation with InterPro:IPR015224 focal adhesion ; GO:0005925 | inferred from direct assay focal adhesion ; GO:0005925 | inferred from sequence or structural similarity "rhea, talin, Talin, CG6831, CT21159, Tln, Rhea, tendrils" "IPR029071:Ubiquitin-related domain, IPR006077:Vinculin/alpha-catenin, IPR002558:I/LWEQ domain, IPR015009:Vinculin-binding site-containing domain, IPR019748:FERM central domain, IPR015224:Talin, central, IPR002404:IRS-type PTB domain, IPR019747:FERM conserved site, IPR011993:PH domain-like, IPR014352:FERM/acyl-CoA-binding protein, 3-helical bundle, IPR019749:Band 4.1 domain, IPR018979:FERM, N-terminal, IPR000299:FERM domain, IPR032425:Talin, N-terminal F0 domain" CG6831 27-Aug-18 DroID_v2018_08 "Drer\tln2a, Drer\mesdc1, Drer\tln2b, Drer\tln1" Scer\SLA2 Cele\tln-1 "Xtro\mesdc1, Xtro\tln2" "Mmus\Tln1, Mmus\Tln2, Mmus\Mesdc1" "Hsap\TLN1, Hsap\TLN2, Hsap\MESDC1" " embryonic stage | stage 12 , embryonic stage | stage 6 , embryonic stage | stage 16 " " ventral nervous system

, organism | ubiquitous

, embryonic midgut

, muscle attachment site

" " embryonic stage | stage 12 , larval stage | third instar , embryonic stage | stage 16 , embryonic stage | stage 6 " " anterior midgut proper primordium && posterior midgut proper primordium

, dorsal mesothoracic disc | restricted

, muscle attachment site

,

" "viable,lethal,visible,somatic clone,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "egg chamber,conditional,muscle attachment site,germline clone,presumptive embryonic/larval muscle system,muscle cell,tendon cell,muscle cell & actin filament & embryo,tendon cell & microtubule & embryo,muscle cell & focal adhesion & embryo,tendon cell & focal adhesion & embryo,tendon cell & basal lamina & embryo,somatic clone,actin filament & follicle cell | somatic clone,embryonic/larval midgut primordium,embryonic proventriculus,germ band,rescuable maternal effect,terminal tracheal cell,oocyte,cell non-autonomous,gastric caecum primordium,wing,embryonic/larval somatic muscle,eye,embryonic/larval tracheal system,embryonic/larval fat body branch,border follicle cell" FBgn0036483 CG12316 - http://flybase.org/reports/FBgn0036483 protein_coding_gene - "histone H4-K16 acetylation ; GO:0043984 | inferred from electronic annotation with InterPro:IPR026711 male courtship behavior, veined wing generated song production ; GO:0045433 | inferred from mutant phenotype" MSL complex ; GO:0072487 | inferred from electronic annotation with InterPro:IPR026711 CG12316 IPR026711:Protein male-specific lethal-1 CG12316 27-Aug-18 DroID_v2018_08 "Drer\msl1b, Drer\msl1a" - - - Mmus\Msl1 Hsap\MSL1 "song defective,partially lethal - majority die,some die during pupal stage" embryonic/larval hemocyte | third instar larval stage DRSC09879 K 0.23269485 0.430565511 0.046557753 0.788846029 1.687490338 0.010109736 FBgn0000022 ac achaete http://flybase.org/reports/FBgn0000022 - protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with da sequence-specific DNA binding ; GO:0043565 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | contributes_to inferred from physical interaction with da sequence-specific DNA binding ; GO:0043565 | contributes_to inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000358347 DNA binding ; GO:0003677 | traceable author statement RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from biological aspect of ancestor with PANTHER:PTN000358347 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with l(1)sc" "neuroblast fate determination ; GO:0007400 | traceable author statement peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | traceable author statement positive regulation of transcription, DNA-templated ; GO:0045893 | traceable author statement chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype central nervous system development ; GO:0007417 | traceable author statement epithelial cell proliferation involved in Malpighian tubule morphogenesis ; GO:0061331 | inferred from mutant phenotype chaeta morphogenesis ; GO:0008407 | non-traceable author statement regulation of neurogenesis ; GO:0050767 | inferred from biological aspect of ancestor with PANTHER:PTN000358354 regulation of transcription, DNA-templated ; GO:0006355 | inferred from sequence or structural similarity with l(1)sc oogenesis ; GO:0048477 | traceable author statement ventral cord development ; GO:0007419 | non-traceable author statement sensory organ development ; GO:0007423 | inferred from mutant phenotype nervous system development ; GO:0007399 | traceable author statement regulation of transcription, DNA-templated ; GO:0006355 | non-traceable author statement regulation of antimicrobial peptide biosynthetic process ; GO:0002805 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN000358347 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype regulation of mitotic cell cycle ; GO:0007346 | traceable author statement Malpighian tubule tip cell differentiation ; GO:0061382 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay RNA polymerase II transcription factor complex ; GO:0090575 | inferred from biological aspect of ancestor with PANTHER:PTN000358347 transcription factor complex ; GO:0005667 | inferred from physical interaction with da "ac, Hw, Ac, EG:125H10.3, CG3796, 990 E5 F1, T5, AS-C T5, AS-C T5ac, ascT5, sc/T5, ASC, AC, AS-C" "IPR015660:Achaete-scute transcription factor-related, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG3796 27-Aug-18 DroID_v2018_08 "Drer\ascl1a, Drer\ascl1b" - "Cele\hlh-14, Cele\hlh-4, Cele\hlh-3" Xtro\ascl2 "Mmus\Ascl1, Mmus\Ascl3, Mmus\Ascl2" "Hsap\ASCL2, Hsap\ASCL5, Hsap\ASCL3, Hsap\ASCL4, Hsap\ASCL1" " embryonic stage , larval stage , embryonic stage | stage 9 , larval stage | third instar , embryonic stage | stage 8 " " stomodeum

, neuroblast

, sensory mother cell

, posterior embryonic/larval midgut

, proneural cluster

, embryonic stomatogastric nervous system

, neuroblast

{ $ N* } , neurogenic region

, neurectoderm

{ $ E(spl)* } , sensory organ cell

, dorsal mesothoracic disc | restricted

, ventral midline

, ectoderm

, procephalic segment

, larval optic lobe | presumptive

, procephalic neuroblast

, embryonic central nervous system

, dorsal mesothoracic disc

, neurectoderm

{ $ Dl* } , neurectoderm

{ $ neur* } , cephalic furrow

, embryonic peripheral nervous system

, labral segment

, ventral neurogenic region

, neurectoderm

{ $ bib* } " " larval stage | third instar , larval stage , embryonic stage | stage 9-11 , embryonic stage | stage 8-9 , embryonic stage , embryonic stage | stage 8 , embryonic stage | stage 8-10 , embryonic stage | stage 8-11 , embryonic stage | stage 9 , wandering third instar larval stage " " dorsal mesothoracic disc

, sensory mother cell

, protocerebral neuroblast | subset

, neuroblast NB3-5

, neurectoderm

{ $ neur* } , proneural cluster

, neurectoderm

{ $ bib* } , neuroblast NB7-4

, wing vein L5

, ectoderm

, deuterocerebral neuroblast | subset

, neuroblast NB7-1

, neuroblast MP2

, procephalic neuroblast | subset

, wing vein L1

{ + h* } , ventral neurogenic region

, wing vein L3

{ + h* } , procephalic neurogenic region | restricted

, neuroblast

{ $ N* } , neurectoderm

{ $ E(spl)* } , neurectoderm

{ $ Dl* } , dorsal mesothoracic disc | dorsal/ventral compartment boundary & restricted " "visible,dominant,recessive,viable,good,wild-type,male sterile,fertile,male fertile,female sterile" "external sensory organ,ectopic,scutellum,wing vein L3,macrochaeta & head,macrochaeta & thorax,sensillum campaniformium,microchaeta,mesothoracic tarsal bristle,mesothoracic metatarsus,macrochaeta,glial cell,wing & nerve,nerve,third segment of antenna,mesothoracic tergum & macrochaeta | ectopic,wing margin bristle,anterior orbital bristle,anterior notopleural bristle,humeral bristle,postvertical bristle,ocellar bristle,presutural bristle,anterior postalar bristle,anterior supraalar bristle,posterior postalar bristle,posterior supraalar bristle,scutellar bristle,dorsocentral bristle,acrostichal bristle,supernumerary,anterior dorsocentral bristle,posterior dorsocentral bristle,microchaeta & mesothoracic pleurum,microchaeta & wing,macrochaeta & abdominal tergite,microchaeta & pleural membrane,interocellar bristle,interommatidial bristle,mesothoracic leg sensillum,posterior notopleural bristle,microchaeta & scutum,microchaeta & scutellum,sensillum campaniformium of proximal dorsal radius,sense organ & wing vein,precursor,macrochaeta & leg,microchaeta & leg,adult thorax & microchaeta,scutum,wing,microchaeta & mesothoracic tergum | supernumerary,neuron,anterior sternopleural bristle,wing vein,posterior crossvein,chaeta,sensory mother cell,sensory mother cell & dorsal mesothoracic disc" DRSC18734 I -1.740211892 -2.639558744 0.435517917 1.190294363 0.396568427 0.114040713 FBgn0026404 Dronc Death regulator Nedd2-like caspase http://flybase.org/reports/FBgn0026404 "FBgn0025326, FBgn0062102" protein_coding_gene cysteine-type endopeptidase activity ; GO:0004197 | traceable author statement cysteine-type endopeptidase activity ; GO:0004197 | inferred from sequence or structural similarity with WB:WBGene00000417 inferred from direct assay cysteine-type endopeptidase activity ; GO:0004197 | inferred from direct assay endopeptidase activity ; GO:0004175 | inferred from direct assay cysteine-type endopeptidase activity involved in apoptotic signaling pathway ; GO:0097199 | inferred from direct assay cysteine-type endopeptidase activity involved in apoptotic signaling pathway ; GO:0097199 | contributes_to inferred from direct assay cysteine-type endopeptidase activity involved in execution phase of apoptosis ; GO:0097200 | inferred from biological aspect of ancestor with PANTHER:PTN000825206 protein homodimerization activity ; GO:0042803 | inferred from direct assay CARD domain binding ; GO:0050700 | inferred from sequence model hemocyte development ; GO:0007516 | inferred from mutant phenotype neuron remodeling ; GO:0016322 | inferred from mutant phenotype positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway ; GO:2001269 | inferred from direct assay programmed cell death involved in cell development ; GO:0010623 | inferred from mutant phenotype neuron remodeling ; GO:0016322 | inferred from mutant phenotype inferred from genetic interaction with Ca-β metamorphosis ; GO:0007552 | traceable author statement programmed cell death ; GO:0012501 | inferred from direct assay salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern ectopic germ cell programmed cell death ; GO:0035234 | inferred from mutant phenotype apoptotic process ; GO:0006915 | traceable author statement head involution ; GO:0008258 | inferred from mutant phenotype embryonic development via the syncytial blastoderm ; GO:0001700 | traceable author statement regulation of retinal cell programmed cell death ; GO:0046668 | non-traceable author statement nurse cell apoptotic process ; GO:0045476 | inferred from genetic interaction with Strica apoptotic process ; GO:0006915 | inferred from mutant phenotype zymogen activation ; GO:0031638 | inferred from direct assay inferred from mutant phenotype embryonic development via the syncytial blastoderm ; GO:0001700 | non-traceable author statement execution phase of apoptosis ; GO:0097194 | inferred from biological aspect of ancestor with PANTHER:PTN000825206 central nervous system development ; GO:0007417 | inferred from mutant phenotype melanization defense response ; GO:0035006 | inferred from mutant phenotype sperm individualization ; GO:0007291 | inferred from mutant phenotype sensory organ development ; GO:0007423 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype apoptotic process ; GO:0006915 | inferred from mutant phenotype inferred from genetic interaction with Diap1 inferred from physical interaction with Diap1 protein autoprocessing ; GO:0016540 | inferred from direct assay compound eye development ; GO:0048749 | inferred from mutant phenotype negative regulation of cell proliferation ; GO:0008285 | inferred from direct assay regulation of cell death ; GO:0010941 | inferred from mutant phenotype regulation of autophagy ; GO:0010506 | inferred from genetic interaction with Atg1 dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype positive regulation of compound eye retinal cell programmed cell death ; GO:0046672 | inferred from mutant phenotype apoptotic process ; GO:0006915 | non-traceable author statement activation of cysteine-type endopeptidase activity involved in apoptotic process ; GO:0006919 | inferred from mutant phenotype salivary gland histolysis ; GO:0035070 | inferred from mutant phenotype apoptotic process ; GO:0006915 | inferred from expression pattern inferred from mutant phenotype autophagic cell death ; GO:0048102 | inferred from expression pattern protein heterooligomerization ; GO:0051291 | inferred from direct assay mitochondrion ; GO:0005739 | NOT inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay apoptosome ; GO:0043293 | inferred from direct assay "Dronc, DRONC, dronc, CG8091, caspase-9, anon-EST:GreesD6, anon-EST:GressD6, anon-WO0118547.313, Nc, Dronc/Casp9, CG8090, Nc\Dronc" "IPR001309:Peptidase C14, p20 domain, IPR002138:Peptidase C14, caspase non-catalytic subunit p10, IPR011029:Death-like domain, IPR015917:Peptidase C14A, caspase catalytic domain, IPR017350:Peptidase C14A, interleukin-1 beta convertase type, IPR029030:Caspase-like domain, IPR033139:Peptidase family C14A, cysteine active site" CG8091 27-Aug-18 DroID_v2018_08 "Drer\LOC798445, Drer\casp8l2, Drer\caspb, Drer\casp3b, Drer\caspxa, Drer\pycard, Drer\gbp3, Drer\casp3a, Drer\LOC101886133, Drer\casp8l1, Drer\casp9, Drer\casp2, Drer\caspbl, Drer\cflara, Drer\zgc:194469, Drer\si:ch211-195h23.3, Drer\caspa, Drer\casp7, Drer\pea15, Drer\zgc:171731, Drer\casp8, Drer\si:dkey-103e21.5, Drer\casp6, Drer\LOC100331324" - "Cele\csp-2, Cele\csp-1, Cele\csp-3, Cele\ced-3" "Xtro\casp9, Xtro\casp6, Xtro\casp7, Xtro\LOC733553, Xtro\casp3, Xtro\casp2, Xtro\pea15, Xtro\casp10, Xtro\casp1" "Mmus\Casp4, Mmus\Casp12, Mmus\Casp2, Mmus\Casp14, Mmus\Cflar, Mmus\Casp1, Mmus\Casp8, Mmus\Gpr89, Mmus\Casp3, Mmus\Casp9, Mmus\Pea15a, Mmus\Casp7, Mmus\Casp6" "Hsap\CASP1, Hsap\CASP14, Hsap\CASP10, Hsap\CFLAR, Hsap\CASP9, Hsap\CASP3, Hsap\PEA15, Hsap\GPR89B, Hsap\GPR89A, Hsap\CASP8, Hsap\CARD8, Hsap\CASP5, Hsap\CASP4, Hsap\CASP12, Hsap\CASP2, Hsap\CASP7, Hsap\CARD17, Hsap\CASP6, Hsap\CARD18, Hsap\CARD16" " adult stage && oogenesis stage , embryonic stage -- adult stage , larval stage | third instar , embryonic stage | early " " egg chamber

, eye disc

, embryonic/larval midgut

,

ubiquitous , embryonic/larval salivary gland

, larval brain

" "visible,lethal - all die before end of P-stage,some die during pharate adult stage,eye color defective,lethal - all die before end of pupal stage,temperature conditional,some die during pupal stage,lethal - all die before end of first instar larval stage,some die during first instar larval stage,increased cell death,lethal - all die before end of embryonic stage,decreased cell death,some die during embryonic stage,female sterile,male sterile,partially,partially lethal - majority die,decreased cell number,lethal,recessive,maternal effect,neuroanatomy defective,short lived,cell death defective,developmental rate defective,melanotic necrosis,cell shape defective,viable,fertile,increased cell number,somatic clone,rescuable maternal effect,chemical resistant,size defective,lethal - all die before end of larval stage,some die during larval stage,male,wild-type" "eye,pigment cell,ommatidium,eye disc,temperature conditional,adult head,eye disc | third instar larval stage,spermatid,cystic bulge,waste bag,spermatogonial cyst,male germline cell,eye photoreceptor cell,eye disc | P-stage,embryonic/larval Malpighian tubule,retina,wing,dorsal multidendritic neuron ddaC,dendrite477,posterior,embryonic/larval fat body | wandering third instar larval stage,neuron,inter-ommatidial precursor cell,supernumerary,salivary gland | pupal stage,postalar bristle,dendriteppk.1.9,retinal pigment cell,melanotic mass,embryonic/larval digestive system,somatic clone,eye-antennal disc,eye disc posterior to the morphogenetic furrow,embryonic/larval hemocyte,imaginal disc,embryonic/larval brain,ventral nerve cord primordium,rescuable maternal effect,ventral trunk epidermis primordium,dorsal ridge primordium,Bolwig organ,ventral nerve cord,ommatidial precursor cluster,embryonic/larval midgut,dendrite,imaginal disc epithelial cell,neuron & ventral nerve cord | ectopic,macrochaeta,sensory mother cell,eo neuron,thecogen cell,embryonic head,arista,egg chamber,male genitalia,neuroblast & larval abdominal segment 3 | late third instar larval stage,neuroblast & larval abdominal segment 4 | late third instar larval stage,neuroblast & larval abdominal segment 5 | late third instar larval stage,neuroblast & larval abdominal segment 6 | late third instar larval stage,neuroblast & larval abdominal segment 7 | late third instar larval stage,embryonic/larval salivary gland | P-stage,embryonic/larval neuromuscular junction,midline glial cell,maternal effect,presumptive embryonic/larval central nervous system,scolopidial neuron,peptidergic neuron,ectopic,cell autonomous,germline clone" FBgn0022943 Cbp20 cap binding protein 20 http://flybase.org/reports/FBgn0022943 - protein_coding_gene mRNA binding ; GO:0003729 | inferred from sequence or structural similarity RNA cap binding ; GO:0000339 | inferred from biological aspect of ancestor with PANTHER:PTN000428749 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9V9K7 "mRNA cis splicing, via spliceosome ; GO:0045292 | inferred from electronic annotation with InterPro:IPR027157 gene silencing by miRNA ; GO:0035195 | inferred from mutant phenotype primary miRNA processing ; GO:0031053 | inferred from mutant phenotype production of siRNA involved in RNA interference ; GO:0030422 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from biological aspect of ancestor with PANTHER:PTN000428749 negative regulation of viral genome replication ; GO:0045071 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000006099 RNA interference ; GO:0016246 | inferred from mutant phenotype" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay spliceosomal complex ; GO:0005681 | inferred from sequence or structural similarity with SGD:S000006099 precatalytic spliceosome ; GO:0071011 | inferred from direct assay nuclear cap binding complex ; GO:0005846 | inferred from biological aspect of ancestor with PANTHER:PTN000428749 microtubule associated complex ; GO:0005875 | inferred from direct assay "CG12357, CBP20, Cbp20, cbp20" "IPR000504:RNA recognition motif domain, IPR034148:NCBP2, RNA recognition motif, IPR027157:Nuclear cap-binding protein subunit 2" CG12357 27-Aug-18 DroID_v2018_08 "Drer\ncbp2, Drer\tmem67" Scer\CBC2 "Cele\ncbp-2, Cele\mks-3" "Xtro\ncbp2, Xtro\tmem67" "Mmus\Tmem67, Mmus\Ncbp2" Hsap\NCBP2 "lethal - all die before end of pupal stage,some die during pupal stage" DRSC16601 E -1.373373642 0.163633029 -0.665405551 -2.095003137 -0.705169843 0.013278262 FBgn0086675 fne found in neurons http://flybase.org/reports/FBgn0086675 protein_coding_gene mRNA binding ; GO:0003729 | inferred from sequence or structural similarity poly(U) RNA binding ; GO:0008266 | inferred from direct assay regulation of mRNA processing ; GO:0050684 | inferred from genetic interaction with elav regulation of RNA metabolic process ; GO:0051252 | inferred from mutant phenotype male courtship behavior ; GO:0008049 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay "fne, CG4396, Fne, cg4396, CR32646, MRE28, BEST:HL02010, BcDNA:RE25290, BcDNA:HL02010, FNE, lincRNA.985" "IPR006548:Splicing factor ELAV/HuD, IPR002343:Paraneoplastic encephalomyelitis antigen, IPR000504:RNA recognition motif domain" CG4396 27-Aug-18 DroID_v2018_08 "Drer\elavl1, Drer\hug, Drer\nol8, Drer\fam213b, Drer\rbms3, Drer\rbms2b, Drer\elavl3, Drer\rbms1a, Drer\elavl2, Drer\rbms2a, Drer\elavl4" "Scer\GBP2, Scer\PAB1" Cele\exc-7 "Xtro\elavl3, Xtro\elavl1, Xtro\elavl2, Xtro\elavl4" "Mmus\Rbms2, Mmus\Fam213b, Mmus\Elavl4, Mmus\Rbms3, Mmus\Elavl1, Mmus\Rbms1, Mmus\Elavl3, Mmus\Elavl2" "Hsap\ELAVL4, Hsap\RBMS2, Hsap\ELAVL2, Hsap\RBMS3, Hsap\ELAVL1, Hsap\FAM213B, Hsap\ELAVL3, Hsap\RBMS1" DRSC20332 IK 0.642261473 -2.601554176 -0.358408268 -0.67421499 -1.500464561 2.034815472 FBgn0039509 bigmax bigmax http://flybase.org/reports/FBgn0039509 protein_coding_gene "protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 transcription factor binding ; GO:0008134 | inferred from electronic annotation with InterPro:IPR032647 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN001039502" "regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001039502 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype muscle organ development ; GO:0007517 | inferred from mutant phenotype salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern adult feeding behavior ; GO:0008343 | inferred from mutant phenotype autophagic cell death ; GO:0048102 | inferred from expression pattern regulation of transcription, DNA-templated ; GO:0006355 | inferred from sequence or structural similarity with Max" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001039502 "CG3350, DmMlx, BIGMAX, bigmax, Bigmax, Mlx, mlx, bHLHd13, cg3350" "IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain, IPR032647:Max-like protein X" CG3350 27-Aug-18 DroID_v2018_08 Drer\mlx "Scer\HMS1, Scer\RTG3" Cele\mxl-2 Xtro\mlx Mmus\Mlx Hsap\MLX "majority die during pharate adult stage,developmental rate defective,lethal,conditional,viable,fertile,partially lethal" DRSC27542 K -0.293881812 0.676708658 -0.386991031 -0.226091023 -1.549114853 -1.001737909 FBgn0025185 az2 az2 http://flybase.org/reports/FBgn0025185 FBgn0022958 protein_coding_gene "nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with gl zinc ion binding ; GO:0008270 | inferred from sequence model" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from sequence or structural similarity with gl" cellular_component ; GO:0005575 | no biological data available "zf43C, CG1605, az2" "IPR006578:MADF domain, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG1605 27-Aug-18 DroID_v2018_08 - - "Cele\mnm-2, Cele\eor-1, Cele\sdz-12" - "Mmus\Gm13212, Mmus\Zfp980, Mmus\Zfp995" "Hsap\ZNF585A, Hsap\ZNF133" " adult stage && oogenesis stage , adult stage | female && oogenesis stage | stage =S10B " " nurse cell

, ovary

, oocyte

" FBgn0262445 mir-133 mir-133 stem loop http://flybase.org/reports/FBgn0262445 miRNA_gene - - - "dme-miR-133, dme-mir-133, miR-133, mir-133, MIR-133, CR43011, CR33574" - CR43011 27-Aug-18 DroID_v2018_08 - - - - - - " embryonic stage , pupal stage " "visible,lethal,lethal - all die before end of embryonic stage,some die during embryonic stage" "eye,wing,wing vein" FBgn0011674 insc inscuteable http://flybase.org/reports/FBgn0011674 "FBgn0010601, FBgn0013468, FBgn0015387" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with corn cytoskeletal adaptor activity ; GO:0008093 | inferred from sequence or structural similarity inferred from mutant phenotype basal protein localization ; GO:0045175 | traceable author statement apical protein localization ; GO:0045176 | inferred from mutant phenotype inferred from physical interaction with corn establishment of mitotic spindle localization ; GO:0040001 | non-traceable author statement peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype asymmetric neuroblast division ; GO:0055059 | traceable author statement protein localization ; GO:0008104 | inferred from mutant phenotype neuroblast fate determination ; GO:0007400 | traceable author statement establishment of mitotic spindle localization ; GO:0040001 | traceable author statement asymmetric neuroblast division ; GO:0055059 | inferred from genetic interaction with Gαi inferred from genetic interaction with pins regulation of asymmetric cell division ; GO:0009786 | inferred from mutant phenotype asymmetric protein localization involved in cell fate determination ; GO:0045167 | non-traceable author statement sensory organ development ; GO:0007423 | traceable author statement asymmetric protein localization involved in cell fate determination ; GO:0045167 | traceable author statement neuroblast fate determination ; GO:0007400 | inferred from direct assay regulation of nervous system development ; GO:0051960 | inferred from mutant phenotype protein localization ; GO:0008104 | non-traceable author statement Malpighian tubule tip cell differentiation ; GO:0061382 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype asymmetric cell division ; GO:0008356 | traceable author statement establishment of mitotic spindle localization ; GO:0040001 | inferred from mutant phenotype somatic muscle development ; GO:0007525 | inferred from mutant phenotype RNA localization ; GO:0006403 | inferred from mutant phenotype asymmetric protein localization ; GO:0008105 | traceable author statement apical cortex ; GO:0045179 | inferred from direct assay apical part of cell ; GO:0045177 | non-traceable author statement apical cortex ; GO:0045179 | traceable author statement cytoplasm ; GO:0005737 | inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay "insc, Ins, nem, l(2)k12405, l(2)05475, 25/17, fam, CG11312, Insc, INSC" "IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical" CG11312 27-Aug-18 DroID_v2018_08 - - Cele\insc-1 - Mmus\Insc Hsap\INSC " embryonic stage | 3-12 hr , embryonic stage | stage <=14 , embryonic stage | stage 13-15 , embryonic stage | stage 10 , embryonic stage | stage 9-11 , embryonic stage | stage 10-12 , embryonic stage | stage >=15 , embryonic stage | stage 4 , embryonic stage | 4-20 hr , embryonic stage | stage 11-13 , adult stage , embryonic stage | stage 10-13 , embryonic stage , embryonic stage | stage 6 " " embryonic central nervous system

, embryonic/larval midgut

, ganglion mother cell

, ventral neurogenic region

, posterior midgut proper primordium

, embryonic/larval hindgut

, procephalic neurogenic region

, sense organ | precursor

, embryonic peripheral nervous system | restricted

, gastric caecum

, myoblast &&of larval muscle system

, embryonic brain

, anterior midgut proper primordium

, embryonic/larval trachea

, Malpighian tubule

, ventral nerve cord | restricted

, neuroblast

, C1 chordotonal organ precursor cell

, embryonic/larval pharynx

" " embryonic stage | stage 13-15 , embryonic stage | stage 10-12 , embryonic stage | stage >=15 , embryonic stage | stage 10-13 , embryonic stage | stage 11-13 , embryonic stage | stage 6 , embryonic stage , embryonic stage | stage 10 , embryonic stage | stage 9-11 , pupal stage | >20 hr " " embryonic/larval midgut

, anterior midgut proper primordium

, embryonic/larval pharynx

, myoblast &&of larval muscle system

, sense organ | precursor

, embryonic/larval hindgut

, procephalic neurogenic region

, ventral nerve cord | restricted

, ganglion mother cell

, posterior midgut proper primordium

, neuroblast

, dorsal mesothoracic disc | restricted

, Malpighian tubule

, gastric caecum

, embryonic/larval trachea

" "lethal,recessive,viable,fertile,some die during immature adult stage,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,partially lethal - majority die,wild-type,neuroanatomy defective,somatic clone,cell polarity defective" "wing,presumptive embryonic/larval peripheral nervous system,chordotonal organ,imaginal disc,scutellar bristle,tormogen cell,trichogen cell,embryonic/larval somatic muscle,pericardial cell,mesothoracic lateral longitudinal muscle,abdominal dorsal oblique muscle,abdominal dorsal transverse muscle,abdominal lateral transverse muscle,abdominal adult muscle precursor cell,abdominal 1 lateral adult muscle precursor cell,abdominal 2 lateral adult muscle precursor cell,abdominal 3 lateral adult muscle precursor cell,abdominal 4 lateral adult muscle precursor cell,abdominal 5 lateral adult muscle precursor cell,abdominal 6 lateral adult muscle precursor cell,abdominal 7 lateral adult muscle precursor cell,mesothoracic ventral oblique muscle,abdominal ventral oblique muscle,somatic muscle,hypodermal muscle of larval abdominal 9,abdominal lateral pentascolopidial chordotonal organ,metathoracic ventral oblique muscle,abdominal ventral longitudinal muscle,metathoracic ventral longitudinal muscle,mesothoracic ventral longitudinal muscle,mesothoracic segment border muscle,metathoracic segment border muscle,abdominal segment border muscle,abdominal lateral longitudinal muscle,Malpighian tubule tip cell,abdominal 1 lch5 neuron,abdominal 2 lch5 neuron,abdominal 3 lch5 neuron,abdominal 4 lch5 neuron,abdominal 5 lch5 neuron,abdominal 6 lch5 neuron,abdominal 7 lch5 neuron,abdominal dorsal acute muscle,dorsal oblique muscle,prothoracic dorsal oblique muscle,mesothoracic dorsal oblique muscle,metathoracic dorsal oblique muscle,mesothoracic dorsal acute muscle 1,metathoracic dorsal acute muscle,abdominal anterior ventral multidendritic neuron vdaa,abdominal vesA neuron,abdominal v'esA neuron,abdominal vesB neuron,abdominal v'esB neuron,abdominal vesC neuron,ventral multidendritic neuron vdaA,ventral multidendritic neuron vdaB,ventral multidendritic neuron vdaC,ventral multidendritic neuron vdaD,abdominal ventral bipolar neuron vbp,adult muscle precursor cell,ganglion mother cell GMC1-1a,ganglion mother cell GMC4-2a,pCC neuron,RP2sib neuron,abdominal ventral multidendritic neuron,neuroblast,RP2 motor neuron,aCC neuron,U neuron,EL neuron,presumptive embryonic/larval central nervous system,presumptive embryonic/larval digestive system,external sensory organ precursor cell I,ventral nerve cord primordium" FBgn0001981 esg escargot http://flybase.org/reports/FBgn0001981 "FBgn0000445, FBgn0011711, FBgn0015967" protein_coding_gene "DNA binding ; GO:0003677 | inferred from direct assay transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001078 | inferred from direct assay" "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype olfactory behavior ; GO:0042048 | inferred from mutant phenotype fusion cell fate specification ; GO:0035156 | traceable author statement negative regulation of DNA endoreduplication ; GO:0032876 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype cell fate specification ; GO:0001708 | inferred from mutant phenotype cell fate determination ; GO:0001709 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype germ-line stem cell population maintenance ; GO:0030718 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | traceable author statement regulation of compound eye pigmentation ; GO:0048076 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | non-traceable author statement open tracheal system development ; GO:0007424 | traceable author statement asymmetric neuroblast division ; GO:0055059 | inferred from genetic interaction with wor, sna gravitaxis ; GO:0042332 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay central nervous system development ; GO:0007417 | inferred from mutant phenotype inferred from genetic interaction with UniProtKB:P08044 maintenance of imaginal histoblast diploidy ; GO:0007489 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from mutant phenotype genital disc development ; GO:0035215 | inferred from mutant phenotype response to nicotine ; GO:0035094 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay branch fusion, open tracheal system ; GO:0035147 | traceable author statement branch fusion, open tracheal system ; GO:0035147 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from sequence or structural similarity nucleus ; GO:0005634 | inferred by curator from GO:0003677 nucleus ; GO:0005634 | inferred from direct assay "esg, CG3758, BG:DS07851.7, l(2)35Ce, l(2)br43, wiz, l(2)esg, l35Ce, dgl, 4B7, br43, shof, l(2)4B7, l(2)07082, flg, Esg" IPR013087:Zinc finger C2H2-type CG3758 27-Aug-18 DroID_v2018_08 "Drer\prdm1a, Drer\snai1b, Drer\scrt1a, Drer\scrt1b, Drer\snai3, Drer\scrt2, Drer\znf410, Drer\snai1a, Drer\snai2" "Scer\YPR015C, Scer\AZF1" "Cele\klf-1, Cele\snai-1, Cele\M03D4.4, Cele\ztf-23, Cele\klu-1, Cele\ces-1" "Xtro\wt1, Xtro\snai2, Xtro\snai1, Xtro\znf410" "Mmus\Zfp410, Mmus\Snai1, Mmus\Scrt1, Mmus\Snai2, Mmus\Snai3, Mmus\Scrt2" "Hsap\ZNF683, Hsap\SCRT1, Hsap\SNAI3, Hsap\ZNF410, Hsap\SCRT2, Hsap\SNAI2, Hsap\ZNF710, Hsap\SNAI1" " larval stage | third instar , embryonic stage | stage 14 , embryonic stage | stage 14-16 , embryonic stage | stage 11 , embryonic stage | stage 16 , embryonic stage | stage 12 , embryonic stage && pupal stage , embryonic stage | stage 8-9 , embryonic stage " " central nervous system

, histoblast nest

, ventral midline

, dorsal mesothoracic disc | presumptive

, head

, ventral thoracic disc | presumptive

, dorsal metathoracic disc primordium

, embryonic/larval trachea

, ventral mesothoracic disc

, dorsal metathoracic disc

, histoblast

, dorsal ridge

, imaginal disc

, peripheral nervous system

, dorsal mesothoracic disc

, ventral neurogenic region

, ventral metathoracic disc

, genital disc

, ventral prothoracic disc

, ectoderm

" " embryonic stage | stage 13 , embryonic stage | stage 15 , embryonic stage | stage 5 " " tracheal fusion cell

, dorsal mesothoracic disc | presumptive

, ventral thoracic disc primordium | restricted & proximal

, dorsal mesothoracic disc

, dorsal metathoracic disc | presumptive

, embryonic/larval anterior spiracle

, genital disc | presumptive

, dorsal metathoracic disc

, ventral thoracic disc | presumptive

" "lethal,recessive,neurophysiology defective,female sterile,visible,dominant,partially lethal - majority die,lethal - all die before end of larval stage,some die during larval stage,viable,fertile,lethal - all die before end of embryonic stage,some die during embryonic stage,smell perception defective,gravitaxis defective,lethal - all die before end of pupal stage,some die during pupal stage,wild-type,somatic clone,heat sensitive,lethal - all die during pupal stage" "rhabdomere R7,embryonic/larval hemocyte | third instar larval stage,eye,macrochaeta & scutum-537.4,microchaeta & scutum-537.4,wing,chordotonal organ,lateral,imaginal disc,embryonic/larval tracheal system,ventral thoracic disc,somatic clone,embryonic/larval dorsal branch 1,embryonic/larval dorsal branch 2,embryonic/larval dorsal branch 3,embryonic/larval dorsal branch 4,embryonic/larval dorsal branch 5,embryonic/larval dorsal branch 6,embryonic/larval dorsal branch 7,embryonic/larval dorsal branch 8,embryonic/larval dorsal branch 9,embryonic/larval dorsal branch 10,embryonic/larval dorsal trunk,secondary pigment cell,tertiary pigment cell,histoblast,testis,macrochaeta,chaeta,adult thorax,thecogen cell,external sensory organ,tergite,sternite,lateral transverse muscle,muscle fiber,germinal proliferation center hub,hub cell,ommatidium,interommatidial bristle,scutellar bristle & trichogen cell455.2,scutellar bristle & tormogen cell455.2,tracheal system,leg,leg sensillum,leg & trichome | somatic clone,embryonic/larval salivary gland | embryonic stage,tracheal air sac,heat sensitive,dorsal air sac primordium tip cell,scutellar bristle,pigment cell,supernumerary" FBgn0259685 crb crumbs http://flybase.org/reports/FBgn0259685 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097 spectrin binding ; GO:0030507 | traceable author statement protein kinase C binding ; GO:0005080 | inferred from physical interaction with aPKC" "morphogenesis of an epithelium=0002009 | traceable author statement <> establishment or maintenance of polarity of embryonic epithelium=0016332 |...<> zonula adherens assembly=0045186 | traceable author statement <> establishment of epithelial cell apical/basal polarity=0045198 | traceable author statement <> compound eye photoreceptor development=0042051 | traceable author statement <> cell morphogenesis involved in Malpighian tubule morphogenesis=0061336 |...<> salivary gland development=0007431 | traceable author statement <> zonula adherens assembly=0045186 |...<> rhabdomere development=0042052 |...<> amnioserosa maintenance=0046665 |...<> establishment or maintenance of epithelial cell apical/basal polarity=0045197 | traceable author statement <> dorsal closure, amnioserosa morphology change=0046664 |...<> cuticle development=0042335 |... genetic interaction with UniProtKB:Q0KHR3,UniProtKB:Q9VX75,UniProtKB:X2JCB3,UniProtKB:X2JFU8 <> zonula adherens maintenance=0045218 |...<> photoreceptor cell maintenance=0045494 |...<> liquid clearance, open tracheal system=0035002 |... genetic interaction with crb <> adherens junction organization=0034332 |...<> negative regulation of Notch signaling pathway=0045746 |... genetic interaction with N <> rhabdomere morphogenesis=0061541 |...<> negative regulation of proteasomal ubiquitin-dependent protein catabolic process=0032435 |... genetic interaction with Prosβ6 <> nuclear chromosome segregation=0098813 |...<> open tracheal system development=0007424 |...<> establishment or maintenance of cell polarity=0007163 |...<> negative regulation of organ growth=0046621 |...<> oogenesis=0048477 |...<> regulation of imaginal disc growth=0045570 |...<> establishment or maintenance of apical/basal cell polarity=0035088 |...<> membrane organization=0061024 |...<> zonula adherens maintenance=0045218 | <> positive regulation of phosphorylation=0042327 |...<> morphogenesis of a polarized epithelium=0001738 | traceable author statement <> compound eye photoreceptor development=0042051 |...<> establishment or maintenance of polarity of follicular epithelium=0016334 |...<> salivary gland morphogenesis=0007435 |...<> protein localization=0008104 | traceable author statement <> protein stabilization=0050821 |...<> centrosome localization=0051642 |...<> nervous system development=0007399 |...<> compound eye morphogenesis=0001745 |...inferred from genetic interaction with ex inferred from genetic interaction with Mer inferred from genetic interaction with kibra <> membrane organization=0061024 | traceable author statement <> cell-cell junction assembly=0007043 | <> morphogenesis of an epithelium=0002009 | <> maintenance of apical/basal cell polarity=0035090 |...<> Malpighian tubule morphogenesis=0007443 |...<> positive regulation of cell proliferation=0008284 |...<> regulation of intracellular protein transport=0033157 |...<> regulation of hippo signaling=0035330 |... genetic interaction with ex inferred from genetic interaction with Mer inferred from genetic interaction with kibra <> regulation of protein localization=0032880 |...<> rhabdomere development=0042052 | <> dorsal closure=0007391 |...<> establishment or maintenance of cell polarity=0007163 | <> photoreceptor cell maintenance=0045494 | <> tube morphogenesis=0035239 |... mutant phenotype" apical plasma membrane ; GO:0016324 | non-traceable author statement apical plasma membrane ; GO:0016324 | inferred from direct assay septate junction ; GO:0005918 | traceable author statement plasma membrane ; GO:0005886 | inferred from direct assay apical plasma membrane ; GO:0016324 | traceable author statement rhabdomere ; GO:0016028 | inferred from direct assay integral component of membrane ; GO:0016021 | traceable author statement subapical complex ; GO:0035003 | traceable author statement plasma membrane ; GO:0005886 | inferred from sequence or structural similarity apicolateral plasma membrane ; GO:0016327 | inferred from direct assay inferred from physical interaction with sdt apicolateral plasma membrane ; GO:0016327 | inferred from direct assay "Crb, crb, far, Crumbs, Crbs, crumb, CT19912, CRB, l(3)j1B5, l(3)07207, 0509/20, 1384/04, l(3)S058104, CG6383, l(3)S050920, DmCrb, crumbs" "IPR018097:EGF-like calcium-binding, conserved site, IPR000152:EGF-type aspartate/asparagine hydroxylation site, IPR000742:EGF-like domain, IPR001791:Laminin G domain, IPR001881:EGF-like calcium-binding domain, IPR013032:EGF-like, conserved site, IPR013320:Concanavalin A-like lectin/glucanase domain, IPR009030:Growth factor receptor cysteine-rich domain" CG6383 27-Aug-18 DroID_v2018_08 "Drer\dpy19l1l, Drer\zgc:158328, Drer\svep1, Drer\adgrl4, Drer\si:ch73-173h19.3, Drer\scube1, Drer\adgrf6, Drer\col28a1a, Drer\gas6, Drer\crb2a, Drer\notch1b, Drer\dlb, Drer\fbn2b, Drer\efemp1, Drer\notch3, Drer\jag1a, Drer\crb1, Drer\jag1b, Drer\sned1, Drer\ltbp3, Drer\jag2a, Drer\LOC562634, Drer\fbln1, Drer\pros1, Drer\jag2b, Drer\notch1a, Drer\fbn2a, Drer\col28a1a, Drer\megf6b, Drer\notch2, Drer\crb2b, Drer\matn3a, Drer\si:ch211-69e5.1, Drer\LOC100535882, Drer\fbln7, Drer\scube3, Drer\LOC100332841" - "Cele\lin-12, Cele\glp-1, Cele\crb-1, Cele\mup-4, Cele\fbn-1, Cele\mua-3, Cele\slt-1" "Xtro\fbn1, Xtro\hgfac, Xtro\notch1, Xtro\matn4, Xtro\ltbp4, Xtro\svep1, Xtro\f12, Xtro\crb1, Xtro\jag1, Xtro\col14a1, Xtro\nell1, Xtro\crb2" "Mmus\Jag1, Mmus\Ltbp4, Mmus\Habp2, Mmus\Dlk2, Mmus\Hgfac, Mmus\Hmcn2, Mmus\Sned1, Mmus\Scube3, Mmus\Fbln7, Mmus\Fbn1, Mmus\Tdgf1, Mmus\Notch4, Mmus\Svep1, Mmus\Col22a1, Mmus\Crb1, Mmus\Fbn2, Mmus\Cfc1, Mmus\Vwde, Mmus\Egfl7, Mmus\Gas6, Mmus\Notch1, Mmus\Pros1, Mmus\Vwa1, Mmus\Cntnap2, Mmus\Jag2, Mmus\Ltbp1, Mmus\Dll4, Mmus\Notch3, Mmus\Matn3, Mmus\Col28a1, Mmus\Vwce, Mmus\Crb2, Mmus\Scube2, Mmus\Notch2, Mmus\Dll3, Mmus\F12, Mmus\Dlk1" "Hsap\SCUBE3, Hsap\F12, Hsap\SNED1, Hsap\EGFL7, Hsap\FBN1, Hsap\PROS1, Hsap\COL22A1, Hsap\LTBP1, Hsap\DLL3, Hsap\DLK2, Hsap\CRB1, Hsap\CRB2, Hsap\FBN3, Hsap\DLK1, Hsap\FBN2, Hsap\FBLN7, Hsap\VWCE, Hsap\CFC1B, Hsap\SVEP1, Hsap\VWA1, Hsap\CNTNAP2, Hsap\NOTCH1, Hsap\EYS, Hsap\MATN3, Hsap\NOTCH3, Hsap\GAS6, Hsap\NOTCH2, Hsap\TDGF1, Hsap\JAG2, Hsap\CFC1, Hsap\LOC100996717, Hsap\DLL4, Hsap\HGFAC, Hsap\HABP2, Hsap\JAG1, Hsap\NOTCH4, Hsap\SCUBE2, Hsap\NOTCH2NL, Hsap\COL14A1" " embryonic stage -- adult stage , embryonic stage | late , embryonic stage " " adult salivary gland primordium

posterior & dorsal , embryonic/larval hindgut

" " embryonic stage | late , larval stage | third instar , adult stage | male , embryonic stage , embryonic stage | stage 8-11 , pupal stage , embryonic stage | stage 16 , adult stage && oogenesis stage " " adult salivary gland primordium

, embryonic/larval garland cell

, ejaculatory bulb

, ectoderm

, optic lobe

, neuroblast

, photoreceptor cell stalk | apical

, hindgut

, embryonic/larval salivary gland

, external sensory organ

, embryonic/larval foregut

, ejaculatory duct

, embryonic peripheral nervous system

, testicular duct

, peripodial epithelium

, stomodeum

, salivary gland imaginal ring

, posterior embryonic/larval midgut

, embryonic/larval hindgut

, Malpighian tubule

, epithelial cell

, seminal vesicle

, follicle cell

, embryonic/larval trachea

, imaginal disc

, stomatogastric nervous system

, endoderm

, chordotonal organ

, male accessory gland

" FBgn0010389 htl heartless http://flybase.org/reports/FBgn0010389 "FBgn0004599, FBgn0022791" protein_coding_gene "fibroblast growth factor-activated receptor activity ; GO:0005007 | inferred from electronic annotation with InterPro:IPR016248 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR016248, InterPro:IPR017441 fibroblast growth factor-activated receptor activity ; GO:0005007 | traceable author statement protein tyrosine kinase activity ; GO:0004713 | non-traceable author statement protein tyrosine kinase activity ; GO:0004713 | inferred from sequence or structural similarity with UniProtKB:P11362" "protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR001245, InterPro:IPR008266, InterPro:IPR016248, InterPro:IPR020635 positive regulation of cell proliferation ; GO:0008284 | inferred from electronic annotation with InterPro:IPR016248 mesoderm migration involved in gastrulation ; GO:0007509 | non-traceable author statement regulation of cell shape ; GO:0008360 | inferred from mutant phenotype mesodermal cell fate determination ; GO:0007500 | inferred from expression pattern glial cell migration ; GO:0008347 | inferred from mutant phenotype germ cell migration ; GO:0008354 | inferred from mutant phenotype heart development ; GO:0007507 | traceable author statement ventral cord development ; GO:0007419 | inferred from mutant phenotype lymph gland development ; GO:0048542 | inferred from mutant phenotype fibroblast growth factor receptor signaling pathway ; GO:0008543 | traceable author statement defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype larval visceral muscle development ; GO:0007523 | inferred from mutant phenotype heart development ; GO:0007507 | inferred from expression pattern central nervous system development ; GO:0007417 | inferred from mutant phenotype glial cell development ; GO:0021782 | inferred from mutant phenotype cell migration ; GO:0016477 | traceable author statement somatic muscle development ; GO:0007525 | inferred from mutant phenotype positive regulation of innate immune response ; GO:0045089 | inferred from mutant phenotype glial cell differentiation ; GO:0010001 | inferred from mutant phenotype gastrulation ; GO:0007369 | non-traceable author statement visceral muscle development ; GO:0007522 | inferred from mutant phenotype gonad development ; GO:0008406 | traceable author statement central nervous system development ; GO:0007417 | inferred from expression pattern gonadal mesoderm development ; GO:0007506 | inferred from mutant phenotype mesoderm migration involved in gastrulation ; GO:0007509 | traceable author statement cardioblast differentiation ; GO:0010002 | inferred from mutant phenotype germ cell migration ; GO:0008354 | traceable author statement muscle fiber development ; GO:0048747 | inferred from mutant phenotype heart development ; GO:0007507 | non-traceable author statement pole cell migration ; GO:0007280 | traceable author statement heart development ; GO:0007507 | inferred from mutant phenotype mesodermal cell migration ; GO:0008078 | inferred from mutant phenotype mesodermal cell migration ; GO:0008078 | traceable author statement fibroblast growth factor receptor signaling pathway ; GO:0008543 | inferred from sequence or structural similarity with UniProtKB:P11362 mesoderm migration involved in gastrulation ; GO:0007509 | inferred from mutant phenotype mesodermal cell fate commitment ; GO:0001710 | inferred from mutant phenotype inferred from genetic interaction with dpp salivary gland development ; GO:0007431 | traceable author statement pericardial nephrocyte differentiation ; GO:0061320 | inferred from mutant phenotype mesodermal cell fate commitment ; GO:0001710 | inferred from mutant phenotype endodermal cell fate determination ; GO:0007493 | inferred from expression pattern protein phosphorylation ; GO:0006468 | non-traceable author statement" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR016248 "Htl, heartless, FGFR, CG7223, i79, i100, i150, j372, EMS2, DFR1, CT39172, CT22273, HTL/FGFR1, dtk1, DmHD-38, Dfr-1, DTRK(FR1), FGF-R2, DFGF-R1, FR1, DFR1/DFGF-R2, DFGF-R2, DFR-1, FGFR2, DPR3, Tk1, HD-38, Fr1, Dtk1, Dfr1, htl" "IPR000719:Protein kinase domain, IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR008266:Tyrosine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR013783:Immunoglobulin-like fold, IPR016248:Fibroblast growth factor receptor family, IPR017441:Protein kinase, ATP binding site, IPR020635:Tyrosine-protein kinase, catalytic domain, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain" CG7223 27-Aug-18 DroID_v2018_08 "Drer\fgfr1b, Drer\si:ch211-167j9.5, Drer\fgfrl1b, Drer\csf1ra, Drer\si:ch73-206d17.1, Drer\flt4, Drer\fgfr3, Drer\fgfrl1a, Drer\styk1, Drer\flt1, Drer\csf1rb, Drer\si:dkey-14o18.6, Drer\tie1, Drer\kita, Drer\pdgfrb, Drer\fgfr1a, Drer\ret, Drer\flt3, Drer\pdgfrl, Drer\pdgfra, Drer\fgfr4, Drer\kdr, Drer\LOC569566, Drer\tek, Drer\kdrl, Drer\fgfr2, Drer\kitb, Drer\tada2b" Scer\SKM1 "Cele\old-1, Cele\igcm-4, Cele\svh-2, Cele\F09A5.2, Cele\egl-15, Cele\kin-9, Cele\R151.1, Cele\C24G6.2, Cele\F09G2.1" "Xtro\flt1, Xtro\csf1r, Xtro\fgfr1, Xtro\styk1, Xtro\tek, Xtro\tie1, Xtro\ret, Xtro\tada2b, Xtro\fgfr3, Xtro\fgfr4, Xtro\pdgfra, Xtro\fgfr2, Xtro\fgfrl1, Xtro\pdgfrl.2, Xtro\kdr, Xtro\pdgfrl, Xtro\flt4" "Mmus\Flt4, Mmus\Fgfr1, Mmus\Flt1, Mmus\Fgfr4, Mmus\Fgfr2, Mmus\Pdgfrl, Mmus\Pdgfra, Mmus\Csf1r, Mmus\Ret, Mmus\Flt3, Mmus\Tie1, Mmus\Styk1, Mmus\Fgfrl1, Mmus\Pdgfrb, Mmus\Tada2b, Mmus\Tek, Mmus\Fgfr3, Mmus\Kdr, Mmus\Kit" "Hsap\TEK, Hsap\TIE1, Hsap\PDGFRL, Hsap\KIT, Hsap\FGFRL1, Hsap\TADA2B, Hsap\PDGFRA, Hsap\STYK1, Hsap\FGFR1, Hsap\FLT3, Hsap\FLT4, Hsap\FGFR2, Hsap\FLT1, Hsap\FGFR4, Hsap\RET, Hsap\CSF1R, Hsap\PDGFRB, Hsap\KDR, Hsap\FGFR3" " embryonic stage | stage 12-16 , embryonic stage | stage 12-13 , embryonic stage | stage 11-12 , embryonic stage | stage 13 , embryonic stage | stage 16 , embryonic stage | stage 9 , embryonic stage | stage 5-9 " " central nervous system

, embryonic/larval hindgut

, myoblast &&of larval muscle system

, abdominal 1--7 lateral transverse muscle 3

, abdominal 1--7 ventral acute muscle 2

, abdominal 1--7 ventral acute muscle 1

, longitudinal connective

, embryonic/larval foregut

, abdominal 1--7 lateral transverse muscle 2

, abdominal 2--7 ventral transverse muscle 1

, somatic mesoderm

, abdominal 1--7 lateral transverse muscle 1

, mesoderm

, head mesoderm

" " larval stage | third instar , embryonic stage | stage 11-12 " " dorsal mesothoracic disc && adepithelial cell | restricted

, mesoderm

" "lethal,recessive,wild-type,cell migration defective,increased cell death,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,somatic clone,increased cell number,viable,visible" "presumptive embryonic salivary gland,visceral mesoderm,muscle founder cell,myoblast,muscle fiber,glial cell,embryonic/larval dorsal vessel,embryonic visceral muscle,embryonic/larval somatic muscle,interface glial cell,hindgut visceral muscle primordium,hindgut visceral muscle fiber,mesoderm,embryonic/larval muscle system,dorsal,heart primordium,axon & ocellus sensory structureBx-MS1096, Mz1277, twi.PB, htlUAS.cMa,axon & mechanosensory neuron & adult headBx-MS1096, Mz1277, twi.PB, htlUAS.cMa,somatic mesoderm,axon & ocellus sensory structure-537.4, htlDN.UAS.cMb,axon & mechanosensory neuron & adult head-537.4, htlDN.UAS.cMb,cardiogenic mesoderm,lymph gland primordium,embryonic pericardial cell,cardioblast,pericardial cell,embryonic/larval pericardial cell,embryonic/larval cardial cell,ventral nerve cord,ventral furrow,somatic clone,corpus cardiacum primordium,longitudinal visceral muscle primordium,longitudinal visceral muscle fiber,dorsal oblique muscle,ventral longitudinal muscle,ventral oblique muscle,lateral transverse muscle,dorsal transverse muscle,mesothoracic dorsal acute muscle 1,metathoracic dorsal acute muscle 1,abdominal 1 dorsal acute muscle 1,abdominal 2 dorsal acute muscle 1,abdominal 3 dorsal acute muscle 1,abdominal 4 dorsal acute muscle 1,abdominal 5 dorsal acute muscle 1,abdominal 6 dorsal acute muscle 1,abdominal 7 dorsal acute muscle 1,embryonic myoblast,germline cell,gonadal sheath proper primordium,embryonic somatic muscle,axon & ocellus sensory structure-537.4,axon & mechanosensory neuron & adult head-537.4,axon & ocellus sensory structure-537.4, htlAB42,axon & mechanosensory neuron & adult head-537.4, htlAB42,subretinal glial cell,somatic clone | third instar larval stage,ventral nerve cord | embryonic stage,embryonic/larval dorsal vessel | embryonic stage,ventral,axon & ocellus sensory structureBx-MS1096, Mz1277, twi.PB, htlYY262/htlAB42,axon & mechanosensory neuron & adult headBx-MS1096, Mz1277, twi.PB, htlYY262/htlAB42,supernumerary,tarsal levator muscle,wing vein L5,wing vein,ectopic,embryonic cardioblast,trichogen cell" FBgn0266751 lncRNA:CR45224 - http://flybase.org/reports/FBgn0266751 non_protein_coding_gene - - - CR45224 - CR45224 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0016991 ms(2)1336A ms(2)1336A http://flybase.org/reports/FBgn0016991 - gene - - - "ms(3)1336A, ms(2)1336A" - - 27-Aug-18 DroID_v2018_08 - - - - - - spermatid FBgn0044400 Scim27 Sensitized chromosome inheritance modifier 27 http://flybase.org/reports/FBgn0044400 gene - female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype - Scim27 - - 27-Aug-18 DroID_v2018_08 - - - - - - "meiotic cell cycle defective,dominant" FBgn0004907 14-3-3zeta 14-3-3zeta http://flybase.org/reports/FBgn0004907 "FBgn0010635, FBgn0019723, FBgn0023038, FBgn0046306, FBgn0064146" protein_coding_gene protein domain specific binding ; GO:0019904 | inferred from electronic annotation with InterPro:IPR000308 protein homodimerization activity ; GO:0042803 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Slob protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with 14-3-3ε protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q45VV3 protein kinase C inhibitor activity ; GO:0008426 | non-traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:A0A0B4K753 "thermosensory behavior ; GO:0040040 | inferred from mutant phenotype chromosome segregation ; GO:0007059 | inferred from mutant phenotype learning or memory ; GO:0007611 | inferred from mutant phenotype protein folding ; GO:0006457 | inferred from direct assay inferred from mutant phenotype oocyte microtubule cytoskeleton polarization ; GO:0008103 | inferred from genetic interaction with 14-3-3ε olfactory learning ; GO:0008355 | non-traceable author statement positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from genetic interaction with Ras85D mitotic cell cycle, embryonic ; GO:0045448 | inferred from mutant phenotype positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with Ras85D protein stabilization ; GO:0050821 | inferred from direct assay inferred from mutant phenotype learning or memory ; GO:0007611 | non-traceable author statement germarium-derived oocyte fate determination ; GO:0007294 | inferred from genetic interaction with 14-3-3ε regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype" plasma membrane ; GO:0005886 | inferred from direct assay nuclear membrane ; GO:0031965 | inferred from direct assay germline ring canal ; GO:0045172 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay nucleus ; GO:0005634 | non-traceable author statement nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "14-3-3zeta, leo, 14-3-3, PAR5, d14-3-3zeta, par-5, Par-5, CG17870, 4-3-3 zeta, D14-3-3zeta, 549, 2G1, 5.11, K, BEST:GH05075, l(2)07103, D14-3-3, l(2)46Ee, l(2)46CFe, 14-3-3ZETA, 14-3-3 zeta, Leo, PAR-5, 14-3-3leo, 14-3-3-zeta, LEO, 14-3-3-Leo" "IPR000308:14-3-3 protein, IPR023409:14-3-3 protein, conserved site, IPR023410:14-3-3 domain" CG17870 27-Aug-18 DroID_v2018_08 "Drer\ywhae1, Drer\ywhaqb, Drer\ywhabl, Drer\ywhabb, Drer\ywhae2, Drer\ywhaqa, Drer\ywhaz, Drer\ywhaba, Drer\ywhag1, Drer\ywhag2, Drer\ywhah" "Scer\BMH1, Scer\BMH2" "Cele\par-5, Cele\ftt-2" "Xtro\ywhah, Xtro\ywhag, Xtro\ywhaq, Xtro\ywhaz, Xtro\ywhab, Xtro\ywhae" "Mmus\Ywhag, Mmus\Ywhaz, Mmus\Cdk5rap2, Mmus\Ywhah, Mmus\Ywhae, Mmus\Sfn, Mmus\Ywhaq, Mmus\Ywhab" "Hsap\YWHAB, Hsap\SFN, Hsap\YWHAG, Hsap\YWHAH, Hsap\YWHAQ, Hsap\YWHAE, Hsap\YWHAZ" " adult stage , embryonic stage , larval stage | third instar , adult stage && oogenesis stage , larval stage " " retina

, adult brain

, ventral nerve cord

, lamina

, adult head

, subesophageal ganglion

, embryonic central nervous system

, optic lobe

, eye disc

, mushroom body

, nurse cell

, thoracico-abdominal ganglion

, oocyte

, antennal lobe

, morphogenetic furrow | posterior to

, larval central nervous system

" " adult stage && oogenesis stage , adult stage , larval stage | third instar , embryonic stage | 16-18hr , embryonic stage | late , embryonic stage | 20 hr , embryonic stage | stage 17 , larval stage " " oocyte

, thoracico-abdominal ganglion

, nurse cell

, ring neuron

, eye disc

, cell body

, synapse

, ellipsoid body

, bouton

, neuromuscular junction

, neuron

, larval muscle system

, morphogenetic furrow | posterior to

, mushroom body

, antennal lobe

" "memory defective,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,learning defective,neurophysiology defective,mitotic cell cycle defective,maternal effect,fertile,wild-type" "eye photoreceptor cell,somatic clone,embryonic/first instar larval cuticle,germline clone,denticle belt,syncytial blastoderm embryo,mitotic cell cycle | maternal effect,follicle cell,border follicle cell,photoreceptor cell,embryonic epidermis,lateral,dorsal,embryo,posterior,filzkorper" DRSC05028 I -2.132383757 -1.133882546 0.502046612 0.1426068 -0.137782331 -0.462856079 FBgn0014018 Rel Relish http://flybase.org/reports/FBgn0014018 "FBgn0011469, FBgn0024223" protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from direct assay transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from direct assay chromatin binding ; GO:0003682 | inferred from biological aspect of ancestor with PANTHER:PTN001193216 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8IRY7 RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from biological aspect of ancestor with PANTHER:PTN001193216 DNA binding ; GO:0003677 | inferred from direct assay RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from direct assay" signal transduction ; GO:0007165 | traceable author statement <> immune response ; GO:0006955 | traceable author statement <> defense response to Gram-negative bacterium ; GO:0050829 |... mutant phenotype <> peptidoglycan recognition protein signaling pathway ; GO:0061057 |... mutant phenotype <> positive regulation of antibacterial peptide biosynthetic process ; GO:0006963 |... expression pattern <> positive regulation of innate immune response ; GO:0045089 |... mutant phenotype <> response to bacterium ; GO:0009617 | traceable author statement <> defense response to Gram-negative bacterium ; GO:0050829 | traceable author statement <> positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria ; GO:0006964 |... mutant phenotype <> innate immune response ; GO:0045087 |... direct assay <> immune response ; GO:0006955 |... mutant phenotype <> NIK/NF-kappaB signaling ; GO:0038061 |... biological aspect of ancestor with PANTHER:PTN001193216 <> I-kappaB kinase/NF-kappaB signaling ; GO:0007249 |... biological aspect of ancestor with PANTHER:PTN001193216 <> positive regulation of defense response to virus by host ; GO:0002230 |... mutant phenotype <> innate immune response ; GO:0045087 | non-traceable author statement <> positive regulation of antibacterial peptide biosynthetic process ; GO:0006963 |... mutant phenotype <> defense response to Gram-negative bacterium ; GO:0050829 |... genetic interaction with PGRP-LE <> cellular response to DNA damage stimulus ; GO:0006974 |... mutant phenotype <> immune response ; GO:0006955 |... expression pattern <> negative regulation of stem cell proliferation ; GO:2000647 |... mutant phenotype <> positive regulation of gene expression ; GO:0010628 |... mutant phenotype <> dendrite morphogenesis ; GO:0048813 |... mutant phenotype <> positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 |... mutant phenotype <> positive regulation of nitric oxide biosynthetic process ; GO:0045429 |... mutant phenotype <> cellular response to amino acid starvation ; GO:0034198 |... mutant phenotype <> defense response to virus ; GO:0051607 |... mutant phenotype <> response to bacterium ; GO:0009617 |... direct assay <> response to cytokine ; GO:0034097 |... biological aspect of ancestor with PANTHER:PTN001193216 <> positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 |... direct assay <> negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 |... biological aspect of ancestor with PANTHER:PTN001193216 <> positive regulation of antibacterial peptide biosynthetic process ; GO:0006963 | non-traceable author statement <> regulation of innate immune response ; GO:0045088 |... mutant phenotype inferred from genetic interaction with brm inferred from genetic interaction with mor <> positive regulation of antifungal peptide biosynthetic process ; GO:0006967 |... mutant phenotype <> positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | traceable author statement <> Toll signaling pathway ; GO:0008063 | traceable author statement <> positive regulation of antibacterial peptide biosynthetic process ; GO:0006963 | traceable author statement <> peripheral nervous system neuron development ; GO:0048935 |... mutant phenotype nucleus ; GO:0005634 | inferred from direct assay nuclear euchromatin ; GO:0005719 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN001193216 I-kappaB/NF-kappaB complex ; GO:0033256 | inferred from biological aspect of ancestor with PANTHER:PTN001193216 "rel, CG11992, REL, ird4, ird, l(3)neo36, Rel, Relish, Rel/NF-kappaB, NF-kappaB, relish, RELI, NFkappaB, Rel-p110, RelA, Rel49" "IPR000451:NF-kappa-B/Dorsal, IPR002110:Ankyrin repeat, IPR002909:IPT domain, IPR008967:p53-like transcription factor, DNA-binding, IPR011539:Rel homology domain (RHD), DNA-binding domain, IPR013783:Immunoglobulin-like fold, IPR014756:Immunoglobulin E-set, IPR020683:Ankyrin repeat-containing domain, IPR033926:NFkappaB IPT domain, IPR032397:Rel homology dimerisation domain" CG11992 27-Aug-18 DroID_v2018_08 "Drer\rel, Drer\relb, Drer\rela, Drer\nfkb1, Drer\nfkb2" - Cele\shn-1 "Xtro\rel, Xtro\nfkb1, Xtro\nfkb2, Xtro\rela" "Mmus\Nfkb2, Mmus\Rel, Mmus\Nfkb1, Mmus\Relb, Mmus\Rela" "Hsap\RELB, Hsap\RELA, Hsap\REL, Hsap\NFKB1, Hsap\NFKB2" " embryonic stage | early , adult stage | female , adult stage && oogenesis stage " nurse cell

"immune response defective,viable,recessive,neuroanatomy defective,visible,fertile,lethal,increased cell death,cold sensitive,dominant,short lived,increased cell number,lethal - all die before end of pupal stage,some die during pupal stage" "dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa,macrochaeta,mesothoracic tergum,ectopic,adult brain,lamina,cold sensitive,dorsocentral bristle,intestinal stem cell,adult posterior midgut epithelium" DRSC16819 E 0.496334294 1.222535901 -0.400910449 2.25077341 0.302072844 -0.43303548 FBgn0262871 lute lute http://flybase.org/reports/FBgn0262871 protein_coding_gene ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 neurogenesis ; GO:0022008 | inferred from mutant phenotype regulation of proteolysis ; GO:0030162 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 neurogenesis ; GO:0022008 | inferred from biological aspect of ancestor with PANTHER:PTN001229949 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN001229949 SCF ubiquitin ligase complex ; GO:0019005 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 "CG5319, CG43226, anon-WO0118547.289, lute, CG14333" "IPR000210:BTB/POZ domain, IPR011705:BTB/Kelch-associated, IPR012983:PHR, IPR011333:SKP1/BTB/POZ domain" CG43226 27-Aug-18 DroID_v2018_08 "Drer\btbd3b, Drer\btbd2, Drer\btbd3a, Drer\btbd6a, Drer\btbd17b, Drer\btbd6b" Scer\YIL001W Cele\tag-30 "Xtro\btbd2, Xtro\btbd1, Xtro\btbd6, Xtro\btbd3" "Mmus\Btbd2, Mmus\Btbd17, Mmus\Btbd1, Mmus\Btbd6, Mmus\Btbd3" "Hsap\BTBD6, Hsap\BTBD17, Hsap\BTBD1, Hsap\BTBD2, Hsap\BTBD3" DRSC25911 K 0.730624677 -0.310276427 -0.779626706 -0.139702429 2.154221261 -0.130102616 FBgn0017456 Ubc84D Ubiquitin conjugating enzyme 84D http://flybase.org/reports/FBgn0017456 - protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with SGD:S000002466 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with SGD:S000002466 cellular_component ; GO:0005575 | no biological data available "ubc, CG12799, Ubc84D, UbcD84" "IPR000608:Ubiquitin-conjugating enzyme E2, IPR016135:Ubiquitin-conjugating enzyme/RWD-like, IPR023313:Ubiquitin-conjugating enzyme, active site" CG12799 27-Aug-18 DroID_v2018_08 "Drer\ube2l3a, Drer\ube2l3b" Scer\UBC4 "Cele\ubc-24, Cele\ubc-18" Xtro\ube2l3 "Mmus\Ube2l6, Mmus\Gm10705, Mmus\Ube2l3" "Hsap\UBE2L3, Hsap\UBE2L6" viable DRSC25384 IK 1.708094409 0.802952012 1.24885621 0.383343257 6.682892325 6.840966 FBgn0003714 tko technical knockout http://flybase.org/reports/FBgn0003714 - protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:O15235 structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:Q29RU1 courtship behavior ; GO:0007619 | traceable author statement response to hypoxia ; GO:0001666 | inferred from direct assay mechanosensory behavior ; GO:0007638 | inferred from mutant phenotype mitochondrial translation ; GO:0032543 | traceable author statement sensory perception of sound ; GO:0007605 | inferred from mutant phenotype response to mechanical stimulus ; GO:0009612 | inferred from mutant phenotype mitochondrial translation ; GO:0032543 | inferred from sequence or structural similarity with UniProtKB:Q29RU1 translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:O15235 male courtship behavior ; GO:0008049 | inferred from mutant phenotype mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:O15235 mitochondrial small ribosomal subunit ; GO:0005763 | traceable author statement mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:Q29RU1 "MRPS12, EG:BACH59J11.1, S12, MRP-S12, CG7925, rps12, mt-rps12, l(1)tko, mRpS12, l(1)3Ab, tko, Tko" "IPR005679:Ribosomal protein S12, bacterial-type, IPR006032:Ribosomal protein S12/S23, IPR012340:Nucleic acid-binding, OB-fold" CG7925 27-Aug-18 DroID_v2018_08 Drer\si:dkey-17e16.10 Scer\MRPS12 Cele\mrps-12 Xtro\mrps12 Mmus\Mrps12 Hsap\MRPS12 "lethal,some die during third instar larval stage,some die during second instar larval stage,wild-type,viable,female sterile,recessive,developmental rate defective,bang sensitive,neuroanatomy defective,somatic clone,lethal - all die before end of larval stage,some die during larval stage,cell lethal,germline clone,visible,courtship behavior defective,male,mating defective,auditory perception defective,female,cold sensitive,chemical sensitive,neurophysiology defective,male limited,behavior defective" "egg,adult antennal lobe projection neuron DL1 adPN,somatic clone,gamma Kenyon cell,macrochaeta" DRSC27125 K 0.400620664 -0.898350641 -1.15436026 0.125075653 1.423632656 2.14779984 FBgn0030350 SelG Selenoprotein G http://flybase.org/reports/FBgn0030350 protein_coding_gene molecular_function ; GO:0003674 | no biological data available calcium ion transport ; GO:0006816 | inferred from biological aspect of ancestor with PANTHER:PTN000423974 blastoderm segmentation ; GO:0007350 | inferred from direct assay embryo development ; GO:0009790 | inferred from direct assay determination of adult lifespan ; GO:0008340 | inferred from direct assay regulation of gastrulation ; GO:0010470 | inferred from direct assay cell redox homeostasis ; GO:0045454 | traceable author statement embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from direct assay immune system process ; GO:0002376 | inferred from biological aspect of ancestor with PANTHER:PTN001047971 endoplasmic reticulum calcium ion homeostasis ; GO:0032469 | inferred from mutant phenotype intracellular membrane-bounded organelle ; GO:0043231 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN000423974 "G-rich, CG1844, dselG, BcDNA:GH03581, SelG, dselK, dSelK, SelK" IPR024491:Selenoprotein SelK/SelG CG1844 27-Aug-18 DroID_v2018_08 Drer\selk - Cele\Y41E3.8 Xtro\selk Mmus\Selenok Hsap\SELENOK "developmental rate defective,lethal - all die before end of embryonic stage,some die during embryonic stage,viable" DRSC19808 I 3.865047298 1.246750564 0.351680904 0.676829115 -0.680738177 -0.465606497 FBgn0037492 CG10050 - http://flybase.org/reports/FBgn0037492 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG10050 IPR005636:DTW CG10050 27-Aug-18 DroID_v2018_08 Drer\dtwd2 - - Xtro\dtwd2 Mmus\Dtwd2 Hsap\DTWD2 viable DRSC12501 I 1.825219104 0.247793754 0.142794582 0.419107609 -0.229254431 -0.125008409 FBgn0032518 RpL24 Ribosomal protein L24 http://flybase.org/reports/FBgn0032518 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from direct assay cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 cytoplasmic translation ; GO:0002181 | traceable author statement centrosome duplication ; GO:0051298 | inferred from mutant phenotype ribosomal large subunit assembly ; GO:0000027 | inferred from biological aspect of ancestor with PANTHER:PTN000846433 assembly of large subunit precursor of preribosome ; GO:1902626 | inferred from biological aspect of ancestor with PANTHER:PTN000846433 ribosome ; GO:0005840 | inferred from direct assay cytosolic ribosome ; GO:0022626 | inferred from direct assay cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement "CG9282, anon-EST:Posey37, anon-EST:Posey242, RpL24, Rp L24, L24, RL24_DROME, Rpl24" "IPR000988:Ribosomal protein L24e-related, IPR011017:TRASH domain" CG9282 27-Aug-18 DroID_v2018_08 Drer\rpl24 "Scer\RPL24A, Scer\RPL24B" Cele\rpl-24.1 Xtro\rpl24 Mmus\Rpl24 Hsap\RPL24 DRSC28724 IEK -2.36034726 -1.632061247 0.017070946 -3.471017496 1.63370372 2.705123609 FBgn0022986 qkr58E-1 quaking related 58E-1 http://flybase.org/reports/FBgn0022986 - protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR004088 "neurogenesis ; GO:0022008 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013" nucleus ; GO:0005634 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "qkr-58-E, CG3613, qrk58E-1, qkr58E-1, QKR58E-1, Qkr58E-1" "IPR004087:K Homology domain, IPR004088:K Homology domain, type 1" CG3613 27-Aug-18 DroID_v2018_08 "Drer\khdrbs1b, Drer\qkia, Drer\qki2, Drer\khdrbs1a, Drer\qkib, Drer\khdrbs2, Drer\khdrbs3" Scer\MSL5 "Cele\asd-2, Cele\Y57G11C.36, Cele\gld-1, Cele\K07H8.9" "Xtro\khdrbs3, Xtro\qki, Xtro\khdrbs1, Xtro\khdrbs2" "Mmus\Khdrbs2, Mmus\Qk, Mmus\Khdrbs3, Mmus\Khdrbs1" "Hsap\KHDRBS3, Hsap\QKI, Hsap\KHDRBS2, Hsap\KHDRBS1" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" DRSC04709 I -1.4465963 2.040712099 0.261037455 -0.355408436 -0.070910723 -0.59231784 FBgn0002573 sens senseless http://flybase.org/reports/FBgn0002573 "FBgn0011709, FBgn0027151, FBgn0036355, FBgn0052120" protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | non-traceable author statement bHLH transcription factor binding ; GO:0043425 | inferred from direct assay transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | contributes_to inferred from direct assay sequence-specific DNA binding ; GO:0043565 | inferred from direct assay" negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype sensory organ development ; GO:0007423 | inferred from mutant phenotype inferred from genetic interaction with sc inferred from genetic interaction with da neuron development ; GO:0048666 | inferred from mutant phenotype photoreceptor cell morphogenesis ; GO:0008594 | inferred from mutant phenotype inferred from genetic interaction with ro peripheral nervous system development ; GO:0007422 | traceable author statement photoreceptor cell differentiation ; GO:0046530 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay sensory organ development ; GO:0007423 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | non-traceable author statement R8 cell differentiation ; GO:0045465 | non-traceable author statement sensory organ precursor cell fate determination ; GO:0016360 | inferred from mutant phenotype chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype positive regulation of rhodopsin gene expression ; GO:0045872 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype sensory organ development ; GO:0007423 | traceable author statement compound eye photoreceptor development ; GO:0042051 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay "Sens, sens, Sen, sense, Ly, CG10714, Ly-1, 1228/04, l(3)70Ad, CG32120, sen, senseless, SENS, Ss, Gfi1, Senseless" IPR013087:Zinc finger C2H2-type CG32120 27-Aug-18 DroID_v2018_08 "Drer\prdm13, Drer\gfi1b, Drer\gfi1aa, Drer\gfi1ab" - "Cele\ztf-30, Cele\pag-3, Cele\B0310.2" "Xtro\gfi1b, Xtro\gfi1" "Mmus\Prdm13, Mmus\Gfi1, Mmus\Gfi1b" "Hsap\TIGD1, Hsap\GFI1, Hsap\PRDM13, Hsap\GFI1B" " embryonic stage | stage 11-12 , embryonic stage | stage >=11 , embryonic stage | stage 11-13 , embryonic stage | stage 10 , embryonic stage | stage 10-12 " " external sensory organ precursor cell I

, adult salivary gland primordium

, salivary gland

, external sensory organ precursor cell IIa

, external sensory organ precursor cell IIb

, lateral ectoderm | restricted

, sensory mother cell

, embryonic peripheral nervous system | restricted

" " embryonic stage | stage 11-14 , embryonic stage | stage 10-14 , larval stage | third instar , embryonic stage | stage >=11 " " salivary gland

, embryonic peripheral nervous system | restricted

, Johnston's organ

, adult salivary gland primordium

, metathoracic femoral chordotonal organ

, sensory mother cell

, mesothoracic femoral chordotonal organ

, photoreceptor cell R8

, prothoracic femoral chordotonal organ

, eye-antennal disc | restricted

, dorsal mesothoracic disc | restricted

" "visible,wild-type,lethal,recessive,cell autonomous,somatic clone,increased cell death,neuroanatomy defective,dominant,lethal - all die before end of pupal stage,some die during pupal stage" "scutellar bristle,ectopic,chordotonal organ,external sensory organ,multidendritic neuron,photoreceptor cell R8,somatic clone,cell non-autonomous,ommatidium,photoreceptor cell R7,chaeta,cell autonomous,tormogen cell,microchaeta,photoreceptor cell R2,photoreceptor cell R5,embryonic/larval salivary gland,dorsal row,ventral row,external sensory organ precursor cell IIa,external sensory organ precursor cell IIb,supernumerary,eo neuron,thecogen cell,trichogen cell,mechanosensory chaeta,postorbital bristle,trichome of the posterior wing margin,embryonic/larval oenocyte precursor,medulla,dorsal multidendritic neuron ddaE & dendrite,abdominal dorsal multidendritic neuron ddaE & dendrite,presumptive embryonic/larval peripheral nervous system,embryonic peripheral nervous system & neuronS122804),PNS glial cell,wing margin,wing,anterior wing margin,posterior wing margin,eye,macrochaeta,sensillum campaniformium of dorsal radius,wing sensillum,sternopleural bristle,leg sensillum,leg,distal,scutum,wing & chaetadpp.blk1,leg & chaetadpp.blk1,scutum & chaetadpp.blk1,mesothoracic bristle,microchaeta & scutellum | ectopicC5,mechanosensory sensory organ,metathoracic bristle,prothoracic tarsal bristle,interommatidial bristle,secondary pigment cell,tertiary pigment cell,axon & photoreceptor cell R7 | somatic clonetub.PU" DRSC09263 K -2.589957165 -1.789978122 FBgn0263773 fok fledgling of Klp38B http://flybase.org/reports/FBgn0263773 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "fok, CG43690, 38B.11, CG10746, Fok, l(2)k07614, noncoding_3938, CG42849" - CG43690 27-Aug-18 DroID_v2018_08 - - - - - - " embryonic stage&&adult stage , embryonic stage | >=4 hr , adult stage " DRSC23907 IK -1.656657316 0.333239024 -0.558448272 0.41287203 0.968085545 2.277447487 FBgn0027111 miple1 midkine and pleiotrophin 1 http://flybase.org/reports/FBgn0027111 FBgn0027731 protein_coding_gene growth factor activity ; GO:0008083 | inferred from electronic annotation with InterPro:IPR020090 heparin binding ; GO:0008201 | inferred from sequence or structural similarity with HGNC:6972 heparin binding ; GO:0008201 | inferred from direct assay mesoderm morphogenesis ; GO:0048332 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype extracellular region ; GO:0005576 | inferred from direct assay "anon-EST:Posey203, CG1221, miple1, miple, Miple" "IPR020090:Pleiotrophin/Midkine, C-terminal domain" CG1221 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile,partially lethal - majority die,some die during pupal stage" DRSC08722 E 0.335569321 1.166520862 1.718786772 -0.049063239 -0.556742077 -0.26566344 FBgn0261930 vnd ventral nervous system defective http://flybase.org/reports/FBgn0261930 protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 transcription factor binding ; GO:0008134 | inferred from physical interaction with D RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from direct assay" brain development ; GO:0007420 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from mutant phenotype pattern specification process ; GO:0007389 | non-traceable author statement ventral cord development ; GO:0007419 | non-traceable author statement dorsal/ventral pattern formation ; GO:0009953 | traceable author statement glial cell development ; GO:0021782 | inferred from mutant phenotype ectoderm development ; GO:0007398 | traceable author statement neuroblast fate determination ; GO:0007400 | traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay neuroblast development ; GO:0014019 | inferred from mutant phenotype neuroblast fate determination ; GO:0007400 | inferred from mutant phenotype ventral cord development ; GO:0007419 | traceable author statement brain development ; GO:0007420 | traceable author statement central nervous system development ; GO:0007417 | non-traceable author statement negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype negative regulation of gene expression ; GO:0010629 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "vnd, vnd/NK-2, EG:118B3.1, CG6172, NK-2, VND, Vnd, dNK-2, l(1)1Bf, NK2, EC6, nk-2, lab, l(1)VE769, l(1)VA208, l(1)RC24, l(1)GA122, l(1)GA100, l(1)EC6, l(1)EA142, Dm-NK2, Nkx2, HDC16822, Dm vnd" "IPR020479:Homeobox domain, metazoa, IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like" CG6172 27-Aug-18 DroID_v2018_08 "Drer\nkx2.2a, Drer\nkx2.3, Drer\meox2a, Drer\nkx2.5, Drer\nkx2.1, Drer\meox2b, Drer\nkx2.4a, Drer\nkx2.2b, Drer\nkx2.9, Drer\nkx2.4b, Drer\nkx3.2, Drer\nkx3-1, Drer\nkx2.7, Drer\meox1, Drer\nkx3.3" - "Cele\ceh-27, Cele\ceh-22" "Xtro\nkx2-1, Xtro\nkx3-1, Xtro\nkx2-3, Xtro\nkx3-2, Xtro\nkx2-2, Xtro\nkx2-6, Xtro\nkx3-3, Xtro\nkx2-5, Xtro\nkx2-8" "Mmus\Nkx2-3, Mmus\Nkx3-2, Mmus\Nkx2-4, Mmus\Nkx2-2, Mmus\Nkx2-1, Mmus\Nkx2-5, Mmus\Nkx3-1, Mmus\Nkx2-9, Mmus\Nkx2-6" "Hsap\NKX2-1, Hsap\NKX2-8, Hsap\NKX3-2, Hsap\NKX3-1, Hsap\NKX2-2, Hsap\NKX2-5, Hsap\NKX2-6, Hsap\NKX2-4, Hsap\NKX2-3" " embryonic stage | stage 11 , embryonic stage | stage 8-11 , embryonic stage | stage >=10 , embryonic stage | stage >=13 , embryonic stage | stage 7-8 , embryonic stage | stage 7,8 " " neuroblast NB1-2

, neuroblast NB2-1

, ventral neurogenic region | restricted

, neuroblast NB4-1

, central nervous system | restricted

, posterior embryonic/larval midgut

, ventral neurogenic region

, neuroblast | subset

, neuroblast NB2-2

, neuroblast NB1-1

, anterior embryonic/larval midgut

, neuroblast NB6-2

, neuroblast NB5-2

, neuroblast NB3-1

, neuroblast NB6-1

, ventral midline

, neuroblast MP2

, neuroblast NB5-1

, neuroblast NB7-2

, neuroblast NB7-1

" " embryonic stage | stage 11 , embryonic stage | stage 8-9 , embryonic stage | stage 9-11 , embryonic stage | stage 8 , embryonic stage | cellular blastoderm " " pCC neuron

, U neuron

, embryonic neuron | subset

, neuroblast | subset

, procephalic neuroblast | subset & ventral

, protocerebral neuroblast | subset

, tritocerebral neuroblast | subset

, ventral midline

, ventral neurogenic region && embryonic antennal segment | ventral & restricted

, deuterocerebral neuroblast | subset

, ventral neurogenic region | restricted

, ventral neurogenic region && embryonic intercalary segment | ventral & restricted

, ventral neurogenic region && embryonic ocular segment | ventral & restricted

" DRSC18849 I -0.241859869 2.117121463 0.355150963 0.282667908 0.720278343 0.92449675 FBgn0085382 CG34353 - http://flybase.org/reports/FBgn0085382 protein_coding_gene - gravitaxis ; GO:0042332 | inferred from mutant phenotype - "CG34353, CG12274, CG12427, CG12873, CG12874, CG12875, CG5566, CG5572" "IPR013098:Immunoglobulin I-set, IPR003961:Fibronectin type III, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype" CG34353 27-Aug-18 DroID_v2018_08 "Drer\esama, Drer\negr1, Drer\si:dkey-11p23.7, Drer\zgc:153911, Drer\zgc:110372, Drer\f11r.1, Drer\opcml, Drer\ntm, Drer\jam2a, Drer\vsig8a, Drer\gpa33, Drer\mxra8a, Drer\si:dkey-65b12.12, Drer\jam3b, Drer\zgc:153073, Drer\lsamp, Drer\mxra8b, Drer\cxcr3.1, Drer\cxadr, Drer\vsig8b, Drer\si:dkey-250k15.10, Drer\igsf11, Drer\jam2b, Drer\f11r.2, Drer\esamb, Drer\si:zfos-1011f11.1, Drer\jam3a" - "Cele\wrk-1, Cele\rig-5" "Xtro\negr1, Xtro\lsamp, Xtro\ntm" "Mmus\Fgfrl1, Mmus\Gm1123, Mmus\Esam, Mmus\Cxadr, Mmus\Lsamp, Mmus\Gpa33, Mmus\Jam2, Mmus\Clmp, Mmus\F11r, Mmus\Jam3, Mmus\Opcml, Mmus\Vsig1, Mmus\Mxra8, Mmus\Vsig2, Mmus\Negr1, Mmus\Vsir, Mmus\Iglon5, Mmus\Vsig8, Mmus\Hepacam2, Mmus\Igsf5, Mmus\Ntm, Mmus\Igsf11" "Hsap\NEGR1, Hsap\CXADR, Hsap\MXRA8, Hsap\VSIG8, Hsap\CLMP, Hsap\SIGLEC15, Hsap\GPA33, Hsap\ESAM, Hsap\VSIG2, Hsap\LSAMP, Hsap\OPCML, Hsap\JAM2, Hsap\JAM3, Hsap\IGLON5, Hsap\IGSF11, Hsap\C1orf204, Hsap\F11R, Hsap\IGSF5, Hsap\NTM, Hsap\VSIG1, Hsap\C10orf54" "gravitaxis defective,viable,visible,partially lethal - majority die,some die during pupal stage" trichogen cell DRSC14563 K -0.037482181 0.020583236 -0.135663034 -0.190642201 2.445820845 -0.480378421 FBgn0025578 Lcp9 Larval cuticle protein 9 http://flybase.org/reports/FBgn0025578 FBgn0035062 protein_coding_gene structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model structural constituent of chitin-based larval cuticle ; GO:0008010 | non-traceable author statement structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 chitin-based cuticle development ; GO:0040003 | inferred from sequence model larval chitin-based cuticle development ; GO:0008363 | non-traceable author statement extracellular region ; GO:0005576 | non-traceable author statement extracellular matrix ; GO:0031012 | inferred from sequence model "LCP9, CG16914, Lcp9, DmelLcp9, lcp9" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG16914 27-Aug-18 DroID_v2018_08 Drer\LOC100003040 - "Cele\F44F1.4, Cele\sdz-30, Cele\math-34" - "Mmus\2410137M14Rik, Mmus\H2-K1" - viable DRSC04287 I -0.327492265 -1.653052684 -1.240325872 0.003798219 -0.601591682 -0.666885759 FBgn0026378 Rep Rab escort protein http://flybase.org/reports/FBgn0026378 - protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR023753 GDP-dissociation inhibitor activity ; GO:0005092 | inferred from electronic annotation with InterPro:IPR018203 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR023753 intracellular protein transport ; GO:0006886 | inferred from electronic annotation with InterPro:IPR001738 small GTPase mediated signal transduction ; GO:0007264 | inferred from electronic annotation with InterPro:IPR018203 neurotransmitter secretion ; GO:0007269 | non-traceable author statement protein geranylgeranylation ; GO:0018344 | inferred from direct assay vesicle-mediated transport ; GO:0016192 | non-traceable author statement perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:P32864 synaptic vesicle ; GO:0008021 | non-traceable author statement aster ; GO:0005818 | inferred from direct assay membrane ; GO:0016020 | inferred from sequence or structural similarity with UniProtKB:P32864 spindle pole ; GO:0000922 | inferred from direct assay Rab-protein geranylgeranyltransferase complex ; GO:0005968 | colocalizes_with inferred from direct assay "REP, CG8432, Rep" "IPR018203:GDP dissociation inhibitor, IPR001738:Rab protein geranylgeranyltransferase component A, IPR023753:FAD/NAD(P)-binding domain" CG8432 27-Aug-18 DroID_v2018_08 Drer\chm "Scer\GDI1, Scer\MRS6" Cele\rep-1 Xtro\chm "Mmus\Chm, Mmus\Chml" "Hsap\CHML, Hsap\CHM" "lethal - all die before end of pupal stage,some die during pupal stage" DRSC07526 K -0.486307421 -0.918564052 -0.99137153 -0.791171118 2.081170851 -0.613765693 FBgn0013746 alien alien http://flybase.org/reports/FBgn0013746 "FBgn0027056, FBgn0063164" protein_coding_gene ligand-dependent nuclear receptor binding ; GO:0016922 | inferred from physical interaction with EcR transcription corepressor activity ; GO:0003714 | inferred from direct assay protein homodimerization activity ; GO:0042803 | inferred from physical interaction with alien nuclear hormone receptor binding ; GO:0035257 | inferred from physical interaction with EcR protein binding ; GO:0005515 | inferred from physical interaction with CSN5 inferred from physical interaction with CSN7 "regulation of cell cycle ; GO:0051726 | inferred from direct assay phagocytosis ; GO:0006909 | inferred from mutant phenotype protein deneddylation ; GO:0000338 | inferred from sequence or structural similarity with HGNC:30747 neurogenesis ; GO:0022008 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs female germ-line stem cell population maintenance ; GO:0036099 | inferred from mutant phenotype germ cell development ; GO:0007281 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay germarium-derived cystoblast division ; GO:0048142 | inferred from mutant phenotype protein stabilization ; GO:0050821 | inferred from mutant phenotype male germ-line cyst encapsulation ; GO:0048140 | inferred from mutant phenotype multicellular organism development ; GO:0007275 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay COP9 signalosome ; GO:0008180 | inferred from direct assay COP9 signalosome ; GO:0008180 | non-traceable author statement COP9 signalosome ; GO:0008180 | inferred from direct assay inferred from physical interaction with CSN5 inferred from physical interaction with CSN7 repressor ecdysone receptor complex ; GO:0008231 | inferred from physical interaction with EcR "Dch2, CSN2, Alien, DCH2, CH2, CG9556, BcDNA:LD10463, alien, Csn2" "IPR000717:Proteasome component (PCI) domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR011990:Tetratricopeptide-like helical domain" CG9556 27-Aug-18 DroID_v2018_08 Drer\cops2 Scer\RPN6 Cele\csn-2 Xtro\cops2 Mmus\Cops2 Hsap\COPS2 embryonic stage " apodeme &&of pharynx

, abdominal 1--7 intrasegmental apodeme 2

, intersegmental apodeme

, intrasegmental apodeme

, abdominal 1--7 intersegmental apodeme

, abdominal 1--7 intrasegmental apodeme 1

" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "ganglion mother cell,trichogen cell,mesothoracic tergum" DRSC03482 K -0.360968071 -0.198849767 -0.142635149 0.796914536 1.889659677 3.183688602 FBgn0024330 MED6 Mediator complex subunit 6 http://flybase.org/reports/FBgn0024330 "FBgn0027700, FBgn0037748, FBgn0063159" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P91641 inferred from physical interaction with UniProtKB:Q9V439 RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from mutant phenotype RNA polymerase II transcription coactivator activity involved in preinitiation complex assembly ; GO:0001128 | inferred from biological aspect of ancestor with PANTHER:PTN000318543 RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8IH24 inferred from physical interaction with UniProtKB:Q9VS38 inferred from physical interaction with UniProtKB:Q9VT57 inferred from physical interaction with UniProtKB:Q9W0P8 transcription coactivator activity ; GO:0003713 | contributes_to inferred from direct assay negative regulation of neuroblast proliferation ; GO:0007406 | inferred from mutant phenotype transcription from RNA polymerase II promoter ; GO:0006366 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype RNA polymerase II transcriptional preinitiation complex assembly ; GO:0051123 | inferred from biological aspect of ancestor with PANTHER:PTN000318543 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from direct assay transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity negative regulation of innate immune response ; GO:0045824 | inferred from mutant phenotype mediator complex ; GO:0016592 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay mediator complex ; GO:0016592 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay core mediator complex ; GO:0070847 | inferred from biological aspect of ancestor with PANTHER:PTN000318543 mediator complex ; GO:0016592 | inferred from sequence or structural similarity "Med6, dMED6, p35, dTRAP32, dMed6, anon-EST:Posey279, Trap32, CG9473, BcDNA:LD15729, MED6, med6" "IPR007018:Mediator complex, subunit Med6, IPR016820:Mediator complex, subunit Med6, metazoa/plant" CG9473 27-Aug-18 DroID_v2018_08 Drer\med6 Scer\MED6 "Cele\mdt-6, Cele\sna-1" Xtro\med6 Mmus\Med6 Hsap\MED6 "viable,fertile,visible,partially lethal - majority die,some die during pupal stage,female sterile,germline clone,recessive,cell lethalcell lethal,somatic clone,lethal - all die before end of larval stage,some die during third instar larval stage,lethal" "chaeta,supernumerary,trichogen cell,mesothoracic tergum,follicle cell,somatic clone,eye,imaginal disc,wing disc" DRSC16500 IK 0.112603655 2.266391193 -0.306104213 0.129206078 1.546150606 0.348712307 FBgn0267821 da daughterless http://flybase.org/reports/FBgn0267821 protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with ac inferred from physical interaction with l(1)sc inferred from physical interaction with sc RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | contributes_to inferred from physical interaction with ase inferred from physical interaction with l(1)sc inferred from physical interaction with sc protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with amos protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with ase inferred from physical interaction with l(1)sc inferred from physical interaction with sc protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with HLH54F RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | contributes_to inferred from physical interaction with ato protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with l(1)sc protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with ac inferred from physical interaction with emc inferred from physical interaction with l(1)sc inferred from physical interaction with sc transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | contributes_to inferred from physical interaction with sc transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with l(1)sc inferred from physical interaction with sc RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | contributes_to inferred from physical interaction with ey transcription factor binding ; GO:0008134 | inferred from genetic interaction with E(spl)m7-HLH inferred from genetic interaction with E(spl)mγ-HLH RNA polymerase II core promoter proximal region sequence-specific DNA binding ; GO:0000978 | inferred from biological aspect of ancestor with PANTHER:PTN000927455 protein homodimerization activity ; GO:0042803 | inferred from physical interaction with da transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with ato bHLH transcription factor binding ; GO:0043425 | inferred from biological aspect of ancestor with PANTHER:PTN000927455 DNA binding ; GO:0003677 | traceable author statement protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with UniProtKB:P10627 RNA polymerase II regulatory region DNA binding ; GO:0001012 | contributes_to inferred from physical interaction with amos" "neurogenesis ; GO:0022008 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | non-traceable author statement chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype sex determination ; GO:0007530 | traceable author statement peripheral nervous system development ; GO:0007422 | traceable author statement positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from direct assay sex determination, primary response to X:A ratio ; GO:0007541 | traceable author statement ovarian follicle cell development ; GO:0030707 | traceable author statement nervous system development ; GO:0007399 | traceable author statement somatic stem cell population maintenance ; GO:0035019 | inferred from mutant phenotype sex determination ; GO:0007530 | non-traceable author statement oogenesis ; GO:0048477 | inferred from mutant phenotype Malpighian tubule tip cell differentiation ; GO:0061382 | inferred from mutant phenotype positive regulation of neuron differentiation ; GO:0045666 | inferred from biological aspect of ancestor with PANTHER:PTN000927455 positive regulation of transcription, DNA-templated ; GO:0045893 | traceable author statement second mitotic wave involved in compound eye morphogenesis ; GO:0016330 | traceable author statement neuron fate commitment ; GO:0048663 | inferred from mutant phenotype R8 cell fate specification ; GO:0045464 | non-traceable author statement oogenesis ; GO:0048477 | traceable author statement cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype sensory organ development ; GO:0007423 | inferred from mutant phenotype inferred from genetic interaction with sens inferred from genetic interaction with sc neuroendocrine cell differentiation ; GO:0061101 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay transcription factor complex ; GO:0005667 | inferred from physical interaction with l(1)sc "da, Da, CG5102, l(2)31Ea, bHLHb22, 5102, DA, l(2)k08611, SC_DA" "IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG5102 27-Aug-18 DroID_v2018_08 "Drer\tcf3a, Drer\LOC101883970, Drer\tcf3b, Drer\tcf4, Drer\tcf12" - Cele\hlh-2 "Xtro\tcf4, Xtro\tcf12, Xtro\tcf3" "Mmus\Tcf12, Mmus\Tcf3, Mmus\Tcf4" "Hsap\TCF3, Hsap\TCF12, Hsap\TCF4" DRSC03517 K -0.214533458 -0.481346584 -0.38401039 -0.59714716 1.88625726 0.524335697 FBgn0003430 slp1 sloppy paired 1 http://flybase.org/reports/FBgn0003430 FBgn0010610 protein_coding_gene "transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay enhancer sequence-specific DNA binding ; GO:0001158 | inferred from direct assay" "regulation of gene expression ; GO:0010468 | inferred from mutant phenotype anterior/posterior axis specification, embryo ; GO:0008595 | non-traceable author statement mesoderm formation ; GO:0001707 | traceable author statement blastoderm segmentation ; GO:0007350 | traceable author statement specification of segmental identity, head ; GO:0007380 | inferred from expression pattern inferred from mutant phenotype inferred from genetic interaction with bcd inferred from genetic interaction with ems inferred from genetic interaction with Kr inferred from genetic interaction with Raf inferred from genetic interaction with rl inferred from genetic interaction with tor inferred from genetic interaction with tsl inferred from genetic interaction with dl heart formation ; GO:0060914 | inferred from mutant phenotype heart development ; GO:0007507 | traceable author statement negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay" nucleus ; GO:0005634 | inferred from direct assay "slp, Slp, Slp1, CG16738, Dmslp1, Slp-1, slp-2, slp-1, FD6, l(2)05965, slp1, FoxG, SLP, sko1, SLP1" "IPR018122:Fork head domain conserved site1, IPR001766:Fork head domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR030456:Fork head domain conserved site 2" CG16738 27-Aug-18 DroID_v2018_08 "Drer\foxq2, Drer\foxk2, Drer\foxd2, Drer\foxd3, Drer\foxg1b, Drer\foxk1, Drer\foxg1a, Drer\foxg1c, Drer\foxb2, Drer\foxj1a, Drer\foxl1, Drer\foxb1b, Drer\foxb1a, Drer\foxg1d, Drer\si:ch211-262e15.1" "Scer\FHL1, Scer\HCM1, Scer\FKH2, Scer\FKH1" "Cele\fkh-9, Cele\pes-1, Cele\lin-31, Cele\fkh-2, Cele\fkh-10, Cele\unc-130" "Xtro\foxd4l1.1, Xtro\foxi4.2, Xtro\foxe3, Xtro\foxj1.2, Xtro\foxd3, Xtro\foxk2, Xtro\foxe1, Xtro\foxb1, Xtro\foxd2, Xtro\foxj1" "Mmus\Foxb1, Mmus\Foxg1, Mmus\Foxk1, Mmus\Foxb2, Mmus\Foxj1, Mmus\Foxl1, Mmus\Foxd3, Mmus\Foxk2" "Hsap\FOXG1, Hsap\FOXL1, Hsap\FOXB2, Hsap\FOXK1, Hsap\FOXJ1, Hsap\FOXB1, Hsap\FOXK2, Hsap\FOXD4, Hsap\FOXD3" " embryonic stage , embryonic stage | stage >7 , embryonic stage | stage 4 , embryonic stage | stage 4 | late , embryonic stage | stage 6 , embryonic stage | stage >=13 , embryonic stage | stage 5 " "

segment polarity , mandibular segment

,

70-100% egg length , organism | pair rule

, intercalary segment

,

71-87% egg length & ventral , labral segment

, embryonic/larval proventriculus

, ventral nerve cord

, embryonic procephalic segment | lateral

,

70-81% egg length & dorsal , organism | even pair rule

, organism | gap

" " embryonic stage | stage 8-11 , embryonic stage | stage 9-11 , embryonic stage | stage 5 , embryonic stage | stage 6,7 " " procephalic neurogenic region && embryonic antennal segment | restricted

, deuterocerebral neuroblast | subset

, procephalic neurogenic region &&of embryonic ocular segment | restricted

, organism | even pair rule

, procephalic neurogenic region && embryonic mandibular segment | restricted

, procephalic neurogenic region && labral segment | restricted

, tritocerebral neuroblast | subset

, protocerebral neuroblast | subset

, procephalic neurogenic region && intercalary segment | restricted

,

segment polarity " "lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,recessive,segment polarity phenotype,cell migration defective,viable,visible,body color defective" "cuticle,denticle belt,lateral process,ventral arm of lacinia,hypostomal sclerite,embryonic/larval dorsal vessel,abdominal 2 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 8 ventral denticle belt,RP2 motor neuron,ectopic,RP2sib neuron,neuroblast NB4-2,neuroblast NB5-3,neuroblast NB3-5,neuroblast NB5-6,embryonic labial segment,embryonic/first instar larval cuticle & abdominal segment 1,embryonic/first instar larval cuticle & abdominal segment 3,embryonic/first instar larval cuticle & abdominal segment 5,embryonic/first instar larval cuticle & abdominal segment 7,embryonic/first instar larval cuticle & mesothoracic segment,head,embryonic head,mandibular segment,labial segment,abdominal segment 1,abdominal segment 2,abdominal segment 3,abdominal segment 4,visceral mesoderm,longitudinal visceral muscle primordium | embryonic stage 12,trichogen cell,mesothoracic tergum" FBgn0010433 ato atonal http://flybase.org/reports/FBgn0010433 - protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with da RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | contributes_to inferred from physical interaction with da" "oenocyte development ; GO:0007438 | inferred from mutant phenotype neuron recognition ; GO:0008038 | inferred from mutant phenotype R8 cell fate specification ; GO:0045464 | traceable author statement sensory perception of sound ; GO:0007605 | inferred from mutant phenotype antennal joint morphogenesis ; GO:0048801 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype cell fate commitment ; GO:0045165 | inferred from mutant phenotype R8 cell differentiation ; GO:0045465 | traceable author statement sensory organ precursor cell fate determination ; GO:0016360 | traceable author statement second mitotic wave involved in compound eye morphogenesis ; GO:0016330 | traceable author statement sensory organ development ; GO:0007423 | traceable author statement male courtship behavior, veined wing generated song production ; GO:0045433 | inferred from mutant phenotype sensory organ precursor cell fate determination ; GO:0016360 | inferred from direct assay optic lobe placode development ; GO:0001748 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from expression pattern eye-antennal disc morphogenesis ; GO:0007455 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | traceable author statement R8 cell fate commitment ; GO:0007460 | inferred from mutant phenotype brain development ; GO:0007420 | inferred from mutant phenotype activation of MAPK activity ; GO:0000187 | traceable author statement Bolwig's organ morphogenesis ; GO:0001746 | inferred from expression pattern R8 cell fate specification ; GO:0045464 | non-traceable author statement sensory organ precursor cell fate determination ; GO:0016360 | inferred from mutant phenotype antennal morphogenesis ; GO:0048800 | inferred from mutant phenotype neuron development ; GO:0048666 | inferred from mutant phenotype epidermal growth factor receptor signaling pathway ; GO:0007173 | inferred from genetic interaction with Egfr smoothened signaling pathway ; GO:0007224 | inferred from genetic interaction with hh sensory organ development ; GO:0007423 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | non-traceable author statement nervous system development ; GO:0007399 | traceable author statement" nucleus ; GO:0005634 | inferred from direct assay "ATO, ato1, CG7508, ato, At, Ato, bHLHa10, ato[Dm]" "IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain, IPR032664:Protein atonal/amos/lin-32" CG7508 27-Aug-18 DroID_v2018_08 "Drer\atoh7, Drer\neurod1, Drer\atoh1c, Drer\atoh1b, Drer\neurod6b, Drer\atoh1a, Drer\neurod4, Drer\neurod6a" - "Cele\cnd-1, Cele\lin-32" "Xtro\atoh7, Xtro\atoh1, Xtro\neurod6, Xtro\neurod4" "Mmus\Neurod1, Mmus\Neurod6, Mmus\Atoh7, Mmus\Neurod4, Mmus\Atoh1" "Hsap\ATOH1, Hsap\NEUROD6, Hsap\ATOH7, Hsap\NEUROD4, Hsap\NEUROD1" " embryonic stage | stage 13 , larval stage | third instar , embryonic stage , larval stage--pupal stage " " embryonic central brain | restricted

, larval protocerebrum

, C1 chordotonal organ precursor cell

, chordotonal organ

, external sensory organ

, eye-antennal disc

, prothoracic chordotonal organ

, chordotonal organ &&of wing

, chordotonal organ of tegula

, morphogenetic furrow

, mesothoracic femoral chordotonal organ

, ventral thoracic disc

, inner proliferation zone

, chordotonal organ of scabellum

, Johnston's organ

" " embryonic stage | stage 9-11 , embryonic stage | stage 13 , adult stage , embryonic stage | stage 8-10 " " deuterocerebral neuroblast | subset

, embryonic ganglion mother cell

, protocerebral neuroblast | subset

, adult brain | restricted

, procephalic neurogenic region &&of embryonic antennal segment | restricted

, procephalic neurogenic region &&of embryonic ocular segment | restricted

, embryonic central brain | restricted

" "neuroanatomy defective,thermotaxis behavior defective,wild-type,recessive,somatic clone,touch sensitivity defective,visible,locomotor behavior defective,song defective,auditory perception defective,neurophysiology defective,partially lethal - majority die,visual behavior defective,behavior defective,uncoordinated,lethal - all die before end of P-stage,some die during pharate adult stage,viable" "eye,neurite,dendrite | adult stage,T neuron T4,T neuron T5,chordotonal organ of wing,supernumerary,ommatidium,photoreceptor cell R8,heat sensitive,photoreceptor cell,somatic clone,antennal segment 3 & fasciclep13),neuron of aristal sensillum,antennal lobe glomerulus,glial cell,antenna,antennal lobe,glial cell & antennap13),sensillum coeloconicum of antennal segment 3,glial cell & antennal lobep13),interneuron & antennal lobep13),pioneer neuron & adult antennal nerve & pupap13),abdominal lateral pentascolopidial chordotonal organ lch5,embryonic/larval oenocyte,sacculus,embryonic/larval oenocyte precursor,oenocyte primordium,C1 chordotonal organ precursor cell,third segment of antenna,Johnston organ,eye photoreceptor cell,eye photoreceptor cell & axon,morphogenetic furrow & filopodium | somatic clone,eye disc,sensillum coeloconicum,abdominal 1 lateral pentascolopidial chordotonal organ lch5,abdominal 2 lateral pentascolopidial chordotonal organ lch5,abdominal 3 lateral pentascolopidial chordotonal organ lch5,abdominal 4 lateral pentascolopidial chordotonal organ lch5,abdominal 5 lateral pentascolopidial chordotonal organ lch5,abdominal 6 lateral pentascolopidial chordotonal organ lch5,abdominal 7 lateral pentascolopidial chordotonal organ lch5,maxillary palp sensillum basiconicum,basiconic sensillum of sacculus,adult antennal nerve,chordotonal organ,scolopidial neuron,eye-antennal disc,morphogenetic furrow,embryonic/larval brain,adult brain,wing,cholinergic neuron,antenna & neuron,Bolwig organ,sensory mother cell,sensory mother cell & antennal disc,ocellus,interommatidial bristle,optic lobe,ommatidial precursor cluster,embryonic antennal sense organ,olfactory neuron & embryonic antennal sense organ,lch5 neuron,chordotonal organ precursor cell & ventral thoracic disc,mitotic cell cycle & eye disc | somatic clone,external sensory organ,ectopic,macrochaeta,photoreceptor cell R7,scutellar bristle,wing vein L3,scutum,adult thorax & macrochaeta109,abdominal sternite bristle,wing sensillum,campaniform sensillum of anterior crossvein,sensory mother cell & dorsal mesothoracic disc109,sensory mother cell & dorsal mesothoracic discptc-559.1,adult head,sensillum basiconicum,sensillum trichodeum,sensillum basiconicum of antennal segment 3,lobula,medulla,optic chiasma,abdominal basiconical sensillum dbd & larva & nerve terminal.PC,multidendritic neuron,macrochaeta & wing | ectopicdpp.blk1,chordotonal organ & wing | ectopicdpp.blk1,sternopleural bristle" FBgn0004170 sc scute http://flybase.org/reports/FBgn0004170 "FBgn0003324, FBgn0003412, FBgn0026842" protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from direct assay transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | contributes_to inferred from physical interaction with da protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with da protein binding ; GO:0005515 | inferred from physical interaction with Bap60 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with l(1)sc sequence-specific DNA binding ; GO:0043565 | contributes_to inferred from physical interaction with da sequence-specific DNA binding ; GO:0043565 | contributes_to inferred from direct assay RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | contributes_to inferred from physical interaction with da transcription factor binding ; GO:0008134 | inferred from genetic interaction with E(spl)m7-HLH inferred from genetic interaction with E(spl)mγ-HLH" "nervous system development ; GO:0007399 | traceable author statement chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype central nervous system development ; GO:0007417 | traceable author statement sex determination ; GO:0007530 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype sex determination, establishment of X:A ratio ; GO:0007540 | non-traceable author statement negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype sex determination ; GO:0007530 | traceable author statement chaeta development ; GO:0022416 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from sequence or structural similarity with l(1)sc regulation of mitotic cell cycle ; GO:0007346 | traceable author statement regulation of transcription, DNA-templated ; GO:0006355 | non-traceable author statement neuroblast fate determination ; GO:0007400 | traceable author statement sex determination ; GO:0007530 | inferred from genetic interaction with Sxl ventral cord development ; GO:0007419 | non-traceable author statement regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype Malpighian tubule tip cell differentiation ; GO:0061382 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | traceable author statement regulation of neurogenesis ; GO:0050767 | inferred from biological aspect of ancestor with PANTHER:PTN000358354 sensory organ development ; GO:0007423 | inferred from mutant phenotype nervous system development ; GO:0007399 | inferred from genetic interaction with sisA sex determination ; GO:0007530 | inferred from genetic interaction with dpn inferred from genetic interaction with dpn, Sxl chaeta morphogenesis ; GO:0008407 | non-traceable author statement peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype" transcription factor complex ; GO:0005667 | inferred from physical interaction with da RNA polymerase II transcription factor complex ; GO:0090575 | inferred from biological aspect of ancestor with PANTHER:PTN000358347 "sc, sis-b, sisB, Sc, EG:198A6.1, CG3827, scalpha, DROACS2, T4, T4 AS-C, scute/sisterlessB, sis b, sisb, AS-C T4sc, Hw, AS-C T4, ascT4, sc/T4, l(1)1Ba, bHLHc28, SC_DA" "IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain, IPR015660:Achaete-scute transcription factor-related" CG3827 27-Aug-18 DroID_v2018_08 "Drer\nhlh2, Drer\tcf23, Drer\tal2, Drer\msc, Drer\mespab, Drer\tcf15, Drer\figla, Drer\mespba, Drer\scxa, Drer\lyl1, Drer\msgn1, Drer\tal1, Drer\ptf1a, Drer\tcf21, Drer\hand2, Drer\ascl1b, Drer\ascl1a, Drer\scxb, Drer\mespaa, Drer\si:ch211-246m6.4, Drer\tcf24" - "Cele\hlh-3, Cele\hlh-14" "Xtro\ptf1a, Xtro\tcf15, Xtro\ascl3, Xtro\hand2, Xtro\msgn1, Xtro\mespb, Xtro\figla, Xtro\hand1, Xtro\lyl1, Xtro\tcf21, Xtro\scx, Xtro\mespa, Xtro\nhlh1, Xtro\msc, Xtro\tal1, Xtro\ascl2" "Mmus\Hand1, Mmus\Tcf15, Mmus\Nhlh2, Mmus\Ascl4, Mmus\Ascl1, Mmus\Ascl5, Mmus\Msc, Mmus\Figla, Mmus\Ferd3l, Mmus\Mesp2, Mmus\Ascl2, Mmus\Lyl1, Mmus\Nhlh1, Mmus\Tal1, Mmus\Msgn1, Mmus\Tal2, Mmus\Ptf1a, Mmus\Tcf23, Mmus\Hand2, Mmus\Tcf21, Mmus\Ascl3, Mmus\Mesp1, Mmus\Scx" "Hsap\TCF24, Hsap\TCF21, Hsap\ASCL4, Hsap\MESP1, Hsap\ASCL2, Hsap\MESP2, Hsap\MSGN1, Hsap\HAND2, Hsap\NHLH1, Hsap\ASCL3, Hsap\FIGLA, Hsap\ASCL1, Hsap\MSC, Hsap\HAND1, Hsap\TAL1, Hsap\NHLH2, Hsap\PTF1A, Hsap\TAL2, Hsap\TCF23, Hsap\SCX, Hsap\TCF15, Hsap\LYL1, Hsap\ASCL5" " embryonic stage ,, larval stage | third instar , larval stage | third instar stage 2 , pupal stage , embryonic stage | cycle 9-13 , embryonic stage | 0-12hr " " labral segment

, neuroblast

, stomodeum

, proneural cluster

, dorsal mesothoracic disc | restricted

, neurogenic region

, ectoderm

, dorsal mesothoracic disc

, embryonic peripheral nervous system

, sensory mother cell

, posterior embryonic/larval midgut

, central nervous system

, adult trachea | precursor

, cleavage nucleus

, ventral midline

, cephalic furrow

, sensory organ cell

, procephalic neuroblast

, procephalic segment

" " embryonic stage , larval stage , larval stage | third instar , embryonic stage | stage 10-11 , embryonic stage | stage 9-11 , embryonic stage | stage 12-14 , embryonic stage -- adult stage " " embryonic/larval hindgut | restricted

, embryonic peripheral nervous system | restricted

, proneural cluster

, dorsal mesothoracic disc | restricted

, sensory mother cell

, embryonic central nervous system

, ectoderm

, procephalic neuroblast | subset

, protocerebral neuroblast | subset

, embryonic stomatogastric nervous system

, neuroblast

, ventral neurogenic region

, wing vein L1

, C1 chordotonal organ precursor cell

, dorsal mesothoracic disc

, procephalic neurogenic region | restricted

, deuterocerebral neuroblast | subset

" "viable,male,reduced,fertile,visible,male sterile,recessive,female sterile,female,lethal,wild-type,male fertile,female fertile,partially lethal - majority die,heat sensitive,sex-determination defective,lethal - all die before end of embryonic stage,some die during embryonic stage,dominant,female limited,partially lethal - majority live,mitotic cell cycle defective,sterile,lethal - all die before end of P-stage,some die during pharate adult stage,flightless" "humeral bristle,postvertical bristle,ocellar bristle,scutellar bristle,anterior orbital bristle,anterior notopleural bristle,presutural bristle,anterior postalar bristle,anterior supraalar bristle,posterior postalar bristle,macrochaeta,ectopic,mesothoracic tergum,wing,mesothoracic tarsal bristle,mesothoracic tarsal bristle longitudinal row 6.5,mesothoracic tarsal bristle longitudinal row 6,anterior dorsocentral bristle,middle orbital bristle,heat sensitive,chaeta,tergite,notal microchaeta,supernumerary,prothoracic leg sensillum,mesothoracic leg sensillum,metathoracic leg sensillum,macrochaeta & leg,head,male,third segment of antenna,mesothoracic tergum & macrochaeta,posterior orbital bristle,posterior supraalar bristle,posterior notopleural bristle,dorsocentral bristle,proboscis & macrochaeta,upper humeral bristle,notopleural bristle,lower humeral bristle,orbital bristle,anterior vertical bristle,supraalar bristle,postalar bristle,sensillum campaniformium of dorsal radius Sc4d,vertical bristle,abdomen,abdominal sternite bristle,sternopleural bristle,anepisternum,posterior vertical bristle,microchaeta,anterior scutellar bristle,mesothoracic tarsal bristle longitudinal row 5.5,mesothoracic tarsal bristle longitudinal row 5,head bristle,posterior dorsocentral bristle,mechanosensory chaeta,posterior scutellar bristle,sternite,wing disc,sensory mother cell,sense organ,dorsal row & glial cell,ventral row & glial cell,anterior notal wing process sensillum campaniformium & glial cell,sensillum campaniformium of anterior crossvein & glial cell,sensillum campaniformium of dorsal radius & glial cell,mesothoracic metatarsus,wing sensillum,dorsal row,ventral row,eo neuron,tormogen cell,medial triple row,adult thoracic sensillum,external sensory organ,wing & external sensory organhs.PB,wing vein L2,multidendritic neuron,scutellum & microchaeta109,wing vein L3,scutum,sensory mother cell & dorsal mesothoracic disc109,sensory mother cell & dorsal mesothoracic discptc-559.1,mesothoracic tergum & macrochaeta | ectopic-C253,haltere,wing & macrochaetadpp.blk1,haltere sensillum,haltere & macrochaetadpp.blk1,macrochaeta & scutellum455.2,adult thorax & microchaetaap-md544,adult thorax & macrochaetaap-md544,mesothoracic tergum & macrochaeta | ectopicap-md544,dorsal medial muscle,chaeta | ectopic & mesothoracic tergumC-765" FBgn0046680 anon-38B.8 anon-38B.8 http://flybase.org/reports/FBgn0046680 gene - - - "38B.8, anon-38B.8" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001150 gt giant http://flybase.org/reports/FBgn0001150 - protein_coding_gene "protein homodimerization activity ; GO:0042803 | inferred from sequence or structural similarity transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from direct assay RNA polymerase II distal enhancer sequence-specific DNA binding ; GO:0000980 | inferred from direct assay transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | inferred from direct assay transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from biological aspect of ancestor with PANTHER:PTN000945219 protein heterodimerization activity ; GO:0046982 | inferred from sequence or structural similarity RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from direct assay" "specification of segmental identity, labial segment ; GO:0007381 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype regulation of cell size ; GO:0008361 | inferred from mutant phenotype zygotic determination of anterior/posterior axis, embryo ; GO:0007354 | traceable author statement ring gland development ; GO:0035271 | inferred from mutant phenotype regulation of transcription involved in anterior/posterior axis specification ; GO:0044324 | inferred from mutant phenotype salivary gland development ; GO:0007431 | traceable author statement regulation of gene expression ; GO:0010468 | inferred from mutant phenotype negative regulation of multicellular organism growth ; GO:0040015 | inferred from mutant phenotype posterior head segmentation ; GO:0035289 | traceable author statement axon guidance ; GO:0007411 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype terminal region determination ; GO:0007362 | inferred from genetic interaction with tor negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | traceable author statement zygotic determination of anterior/posterior axis, embryo ; GO:0007354 | non-traceable author statement torso signaling pathway ; GO:0008293 | inferred from genetic interaction with tor negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay" nucleus ; GO:0005634 | inferred from direct assay "gt, Giant, EG:BACH7M4.5, CG7952, GIAN_DROME, l(1)giant, l(1)3Aa, Gt, GT, DM17" "IPR004827:Basic-leucine zipper domain, IPR029859:Protein giant, IPR015943:WD40/YVTN repeat-like-containing domain" CG7952 27-Aug-18 DroID_v2018_08 "Drer\dbpa, Drer\nfil3-5, Drer\cebp1, Drer\tefa, Drer\cebpb, Drer\si:dkey-172o19.2, Drer\tefb, Drer\dbpb, Drer\ddit3, Drer\hlfb, Drer\hlfa, Drer\nfil3-2, Drer\nfil3-4" - "Cele\zip-6, Cele\zip-7, Cele\atf-8, Cele\ces-2" "Xtro\hlf, Xtro\dbp, Xtro\cebpb" "Mmus\Tef, Mmus\Cebpe, Mmus\Cebpb, Mmus\Cebpa, Mmus\Hlf, Mmus\Dbp" "Hsap\DBP, Hsap\TEF, Hsap\HLF, Hsap\CEBPA" " embryonic stage | gastrulation , embryonic stage | extended germ band stage , embryonic stage | cellular blastoderm , embryonic stage | extended germ band , embryonic stage | stage 4 , embryonic stage | stage 5 , embryonic stage | embryonic cycle 13 , embryonic stage | embryonic cycle 12,13 , embryonic stage | embryonic cycle 12 " "

anterior{ + kni* } , anterior embryonic/larval midgut

{ + Kr* } ,

20-25% egg length{ 0 kni* } , labral segment

,

33-45% egg length{ 0 Kr* } ,

90-100% egg length , organism | 60-70% egg length

, organism | 70-80% egg length

, organism | 20-30% egg length

,

anterior{ 0 eve* } ,

anterior{ + hb* } ,

14-20% egg length{ 0 hb* } , organism | 60-80% egg length

, cephalic furrow

, organism | 50-90% egg length

, organism | 0-30% egg length

, organism | 90-100% egg length

,

20-40% egg length " " embryonic stage , embryonic stage | stage 5 , embryonic stage | embryonic cycle 12 , embryonic stage | embryonic cycle 13 " " maxillary segment

, organism | 90-100% egg length

, labrum

, ring gland

, organism | 20-40% egg length

, mandibular segment

, organism | 0-30% egg length

, organism | 60-80% egg length

, organism | 10-20% egg length

, organism | 60-70% egg length

, organism | 70-80% egg length

" "lethal,recessive,visible,viable,body size defective,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,size defective" "larval salivary gland & embryo & nuclear chromosome,prothoracic gland innervating neuron PG-LP,prothoracic gland,nucleus | third instar larval stage,mesothoracic segment,metathoracic segment,abdominal segment 2,abdominal segment 3,abdominal segment 4,abdominal segment 5,embryonic/first instar larval cuticle,salivary gland,dorsal hair,ectopic,denticle belt,embryonic labial segment,embryonic prothoracic segment,dorsal ridge,abdominal 6 ventral denticle belt,hypostomal sclerite,embryonic abdominal segment,embryonic abdominal segment 6,embryonic abdominal segment 7,peripheral nervous system,chordotonal organ,lateral,larval abdominal segment 6,larval abdominal segment 7,embryonic stomatogastric nervous system,corpus cardiacum primordium,mouth hooks,hypophysis,embryonic/larval labial organ,larval head,abdominal 5 ventral denticle belt,abdominal 7 ventral denticle belt,abdominal 8 ventral denticle belt,embryonic head,embryonic abdominal segment 5,labial segment,thorax,anterior,abdominal segment 6,abdominal segment 7,larva" FBgn0004197 Ser Serrate http://flybase.org/reports/FBgn0004197 "FBgn0003111, FBgn0003355" protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097 receptor binding ; GO:0005102 | non-traceable author statement Notch binding ; GO:0005112 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VUX2 Notch binding ; GO:0005112 | inferred from physical interaction with N Notch binding ; GO:0005112 | non-traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with mib1" "salivary gland development ; GO:0007431 | non-traceable author statement dorsal/ventral lineage restriction, imaginal disc ; GO:0007451 | traceable author statement Notch signaling pathway ; GO:0007219 | inferred from mutant phenotype crystal cell differentiation ; GO:0042688 | inferred from mutant phenotype imaginal disc-derived leg segmentation ; GO:0036011 | inferred from mutant phenotype lymph gland crystal cell differentiation ; GO:0035170 | traceable author statement imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype second mitotic wave involved in compound eye morphogenesis ; GO:0016330 | inferred from mutant phenotype crystal cell differentiation ; GO:0042688 | traceable author statement negative regulation of lamellocyte differentiation ; GO:0035204 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype sensory organ development ; GO:0007423 | inferred from mutant phenotype Notch signaling pathway ; GO:0007219 | non-traceable author statement lateral inhibition ; GO:0046331 | inferred from mutant phenotype glial cell proliferation ; GO:0014009 | inferred from mutant phenotype larval salivary gland morphogenesis ; GO:0007436 | inferred from mutant phenotype compound eye development ; GO:0048749 | traceable author statement negative regulation of Notch signaling pathway ; GO:0045746 | inferred from direct assay regulation of crystal cell differentiation ; GO:0042689 | traceable author statement larval lymph gland hemopoiesis ; GO:0035167 | inferred from expression pattern germ-line stem cell population maintenance ; GO:0030718 | inferred from genetic interaction with Dl eye-antennal disc development ; GO:0035214 | inferred from mutant phenotype salivary gland morphogenesis ; GO:0007435 | non-traceable author statement cuticle pattern formation ; GO:0035017 | inferred from mutant phenotype" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011651 axolemma ; GO:0030673 | inferred from direct assay cell surface ; GO:0009986 | inferred from direct assay integral component of membrane ; GO:0016021 | non-traceable author statement apical plasma membrane ; GO:0016324 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "Ser, ser, CT18858, Bd, Rpw, std, mel(3)8, CG6127, SER" "IPR018097:EGF-like calcium-binding, conserved site, IPR000152:EGF-type aspartate/asparagine hydroxylation site, IPR000742:EGF-like domain, IPR001774:Delta/Serrate/lag-2 (DSL) protein, IPR001881:EGF-like calcium-binding domain, IPR011651:Notch ligand, N-terminal domain, IPR013032:EGF-like, conserved site, IPR009030:Growth factor receptor cysteine-rich domain, IPR026219:Jagged/Serrate protein, IPR001007:VWFC domain" CG6127 27-Aug-18 DroID_v2018_08 "Drer\jag1b, Drer\jag1a, Drer\adgrf6, Drer\sned1, Drer\fbln7, Drer\LOC100332841, Drer\col28a1a, Drer\jag2b, Drer\adgrl4, Drer\scube3, Drer\LOC562634, Drer\megf6b, Drer\scube1, Drer\svep1, Drer\crb2b, Drer\jag2a, Drer\zgc:158328, Drer\matn3a, Drer\fbln1, Drer\LOC100535882, Drer\si:ch73-173h19.3, Drer\crb2a, Drer\ltbp3, Drer\dlb, Drer\col28a1a, Drer\efemp1, Drer\dpy19l1l" - Cele\apx-1 "Xtro\col14a1, Xtro\fbn1, Xtro\ltbp4, Xtro\jag1, Xtro\crb2, Xtro\f12, Xtro\nell1, Xtro\svep1, Xtro\hgfac, Xtro\notch1, Xtro\matn4" "Mmus\Ltbp4, Mmus\Matn3, Mmus\Dll4, Mmus\Col22a1, Mmus\Egfl7, Mmus\Scube2, Mmus\Crb2, Mmus\Jag2, Mmus\Vwa1, Mmus\Col28a1, Mmus\Sned1, Mmus\Vwce, Mmus\Cfc1, Mmus\Hmcn2, Mmus\F12, Mmus\Jag1, Mmus\Tdgf1, Mmus\Dlk2, Mmus\Ltbp1, Mmus\Scube3, Mmus\Fbn1, Mmus\Dll3, Mmus\Habp2, Mmus\Svep1, Mmus\Dlk1, Mmus\Hgfac, Mmus\Fbln7, Mmus\Vwde" "Hsap\F12, Hsap\COL22A1, Hsap\SCUBE3, Hsap\HGFAC, Hsap\CFC1B, Hsap\DLK1, Hsap\DLL3, Hsap\VWCE, Hsap\EYS, Hsap\LOC100996717, Hsap\SNED1, Hsap\HABP2, Hsap\CRB2, Hsap\DLL4, Hsap\LTBP1, Hsap\SVEP1, Hsap\DLK2, Hsap\NOTCH2NL, Hsap\CFC1, Hsap\TDGF1, Hsap\SCUBE2, Hsap\FBLN7, Hsap\EGFL7, Hsap\VWA1, Hsap\COL14A1, Hsap\MATN3, Hsap\JAG2, Hsap\JAG1" " embryonic stage , adult stage | female , larval stage | third instar , embryonic stage | 2-4 hr , adult stage | male " " epidermis | stripes

, embryonic/larval foregut

, alula

, stomodeum

, embryonic/larval proventriculus

, embryonic/larval salivary gland

, trachea

, maxillary lobe

, mandibular segment

, embryonic salivary gland

, embryonic/larval hindgut

, embryonic/larval posterior spiracle

, central nervous system

, embryonic/larval hypopharynx

, supraesophageal ganglion

, labial segment

, labral segment

, embryonic/larval anterior spiracle

, embryonic/larval pharynx

, maxillary segment

, frontal head air sac | ventral

, dorsal mesothoracic disc

, anal pad

, epidermis

, telson

" " embryonic stage , larval stage | third instar " " embryonic/larval posterior spiracle

, stomodeum

, dorsal mesothoracic disc

, embryonic/larval pharynx

, embryonic/larval salivary gland

, supraesophageal ganglion

, mandibular segment

, epidermis

, frontal head air sac | ventral

, embryonic/larval foregut

, commissure

, labial segment

, alula

, embryonic/larval hindgut

, trachea

, embryonic/larval anterior spiracle

, labral segment

, epidermis | stripes

, maxillary segment

, anal pad

, embryonic/larval proventriculus

" "neuroanatomy defective,visible,viable,dominant,mitotic cell cycle defective,recessive,lethal - all die before end of pupal stage,some die during pupal stage,lethal,cold sensitive,heat sensitive,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage,somatic clone,cell polarity defective,male fertile,size defective,homeotic,lethal - all die before end of P-stage,some die during pharate adult stage,body color defective" "interface glial cell,wing vein,wing margin,wing,distal,proneural cluster,optic lobe,glial cell,haltere,mesothoracic metatarsus,mesothoracic tarsal segment 2,metathoracic tarsal segment 2,prothoracic metatarsus,prothoracic tarsal segment 2,metathoracic metatarsus,crystal cell,embryonic head,mouth hooks,leg,tibia,femur,anterior,heat sensitive,eye,cold sensitive,adult heart,embryonic/larval anterior spiracle,papilla of larval anterior spiracle,wing disc,commissure,axon,dorsal closure embryo,denticle,cuticle,dorsal hair,dorsal compartment,somatic clone,joint,leg & joint,tarsal segment 1 & joint,tarsal segment 2 & joint,tarsal segment 3 & joint,tarsal segment 4 & joint,tarsal segment 5 & joint,denticle row 3 & abdominal 2 ventral denticle belt,denticle row 4 & abdominal 2 ventral denticle belt,denticle row 3 & abdominal 3 ventral denticle belt,denticle row 4 & abdominal 3 ventral denticle belt,denticle row 3 & abdominal 4 ventral denticle belt,denticle row 4 & abdominal 4 ventral denticle belt,denticle row 3 & abdominal 5 ventral denticle belt,denticle row 4 & abdominal 5 ventral denticle belt,denticle row 3 & abdominal 6 ventral denticle belt,denticle row 4 & abdominal 6 ventral denticle belt,denticle row 3 & abdominal 7 ventral denticle belt,denticle row 4 & abdominal 7 ventral denticle belt,denticle row 3 & abdominal 8 ventral denticle belt,denticle row 4 & abdominal 8 ventral denticle belt,dorsal pouch,dorsal bridge,lateral process,embryonic/larval proventriculus,embryonic/larval digestive system,hub cell,salivary gland imaginal ring,macrochaeta,ectopic,dorsal/ventral compartment boundary,actin filament & larval salivary gland,denticle row 3,denticle row 4,adult abdominal segment 4,adult abdominal segment 5,adult abdominal segment 6,adult abdominal segment 7,procrystal cell,embryonic/larval salivary gland duct,presumptive embryonic/larval nervous system,embryonic epidermis,eye disc,dorsal,ventral,antenna,morphogenetic furrow,eye-antennal disc,supernumerary,medulla,ommatidium,interommatidial bristle,pigment cell,lens,eye photoreceptor cell,photoreceptor cell R7,ventral compartment,neuron,embryonic/larval proventriculus | embryonic stage,embryonic/larval digestive system | embryonic stage,presutural bristle & trichogen celll(3)31-1-31-1,anterior notopleural bristle & trichogen celll(3)31-1-31-1,posterior notopleural bristle & trichogen celll(3)31-1-31-1,anterior supraalar bristle & trichogen celll(3)31-1-31-1,posterior supraalar bristle & trichogen celll(3)31-1-31-1,anterior postalar bristle & trichogen celll(3)31-1-31-1,posterior postalar bristle & trichogen celll(3)31-1-31-1,anterior dorsocentral bristle & trichogen celll(3)31-1-31-1,posterior dorsocentral bristle & trichogen celll(3)31-1-31-1,anterior scutellar bristle & trichogen celll(3)31-1-31-1,microchaeta,scutum & macrochaeta & trichogen celll(3)31-1-31-1,tarsal segment,wing & macrochaetadpp.blk1,wing sensillum,macrochaeta & wingptc-559.1,dorsal row,ventral row,wing margin bristle,wing & macrochaeta | dorsalBx-MS1096,scutum & macrochaetaBx-MS1096,scutum,macrochaeta & wingh-540.3,tarsal segment 4,embryonic/larval lymph gland | larval stage,embryonic/larval lymph gland,rhabdomere,eye photoreceptor cell & eye disc | posterior-537.4,macrochaeta & thorax | supernumerary-537.4,eye photoreceptor cell & eye disch-H10,macrochaeta & scutellum | supernumerary | somatic clone | cell autonomous-109-68,macrochaeta & thorax | supernumerary | somatic cloneUbx.PdC,macrochaeta & thorax | somatic cloneUbx.PdC,trichogen cell,mesothoracic tergum" FBgn0259212 cno canoe http://flybase.org/reports/FBgn0259212 protein_coding_gene protein domain specific binding ; GO:0019904 | inferred from physical interaction with pins protein binding ; GO:0005515 | inferred from physical interaction with Ran cell adhesion molecule binding ; GO:0050839 | inferred from biological aspect of ancestor with PANTHER:PTN001624603 Ras GTPase binding ; GO:0017016 | inferred from physical interaction with Rap1 "establishment of mitotic spindle orientation ; GO:0000132 | inferred from mutant phenotype inferred from genetic interaction with Ran inferred from genetic interaction with pins Ras protein signal transduction ; GO:0007265 | traceable author statement ommatidial rotation ; GO:0016318 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from genetic interaction with zip, PDZ-GEF second mitotic wave involved in compound eye morphogenesis ; GO:0016330 | inferred from mutant phenotype regulation of JNK cascade ; GO:0046328 | inferred from mutant phenotype inferred from genetic interaction with bsk embryonic morphogenesis ; GO:0048598 | inferred from mutant phenotype adherens junction organization ; GO:0034332 | inferred from biological aspect of ancestor with PANTHER:PTN001624603 compound eye development ; GO:0048749 | inferred from genetic interaction with mbt dorsal closure, elongation of leading edge cells ; GO:0007394 | non-traceable author statement glial cell proliferation ; GO:0014009 | inferred from mutant phenotype regulation of protein localization ; GO:0032880 | inferred from direct assay inferred from mutant phenotype epidermis morphogenesis ; GO:0048730 | inferred from mutant phenotype cell adhesion ; GO:0007155 | inferred from biological aspect of ancestor with PANTHER:PTN001624603 regulation of JNK cascade ; GO:0046328 | non-traceable author statement JNK cascade ; GO:0007254 | non-traceable author statement establishment or maintenance of cell polarity ; GO:0007163 | non-traceable author statement Notch signaling pathway ; GO:0007219 | traceable author statement dorsal closure ; GO:0007391 | inferred from mutant phenotype dorsal closure ; GO:0007391 | traceable author statement" cell-cell junction ; GO:0005911 | inferred from electronic annotation with InterPro:IPR028842 adherens junction ; GO:0005912 | non-traceable author statement cell cortex ; GO:0005938 | inferred from direct assay zonula adherens ; GO:0005915 | traceable author statement adherens junction ; GO:0005912 | traceable author statement connecting hemi-adherens junction ; GO:0005926 | inferred from direct assay adherens junction ; GO:0005912 | inferred from direct assay adherens junction ; GO:0005912 | colocalizes_with inferred from direct assay "cno, EC3-10, CG42312, Cno, Canoe, lip, mis, dlhA, CG2534, anon-WO0172774.47, AF-6, CG31537, canoe, cno?" "IPR000159:Ras-associating (RA) domain, IPR000253:Forkhead-associated (FHA) domain, IPR001478:PDZ domain, IPR002710:Dilute domain, IPR008984:SMAD/FHA domain, IPR029071:Ubiquitin-related domain, IPR028842:Afadin" CG42312 27-Aug-18 DroID_v2018_08 "Drer\radil, Drer\rasip1, Drer\mllt4a" Scer\SEC3 Cele\afd-1 "Xtro\mllt4, Xtro\rasip1" "Mmus\Rasip1, Mmus\Afdn, Mmus\Radil" "Hsap\RASIP1, Hsap\AFDN, Hsap\RADIL" " embryonic stage -- adult stage , embryonic stage | stage 5 , embryonic stage | stage 10 , embryonic stage | stage 13 , embryonic stage | stage 7-10 , embryonic stage , larval stage " " organism | restricted

,

ubiquitous , ectoderm

, embryonic/larval proventriculus

, posterior embryonic/larval midgut

, epidermis

, organism | striped

, eye-antennal disc

" FBgn0030608 Lsd-2 Lipid storage droplet-2 http://flybase.org/reports/FBgn0030608 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with klar regulation of transport ; GO:0051049 | inferred from mutant phenotype lipid storage ; GO:0019915 | inferred from expression pattern inferred from mutant phenotype lipid metabolic process ; GO:0006629 | inferred from mutant phenotype lipid transport ; GO:0006869 | inferred from expression pattern lipid particle transport along microtubule ; GO:0031887 | inferred from mutant phenotype negative regulation of lipid catabolic process ; GO:0050995 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype sequestering of triglyceride ; GO:0030730 | inferred from mutant phenotype lipid storage ; GO:0019915 | inferred from expression pattern lipid particle ; GO:0005811 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay "145098_at, LSD2, CG9057, Lsd2, LSD-2, Lsd-2, LSP-2, plin2, PLIN2, DmPLIN2" IPR004279:Perilipin CG9057 27-Aug-18 DroID_v2018_08 "Drer\plin2, Drer\zgc:77486, Drer\zgc:162150, Drer\si:rp71-61h23.4" - - "Xtro\plin1, Xtro\plin3" "Mmus\Plin2, Mmus\Plin3, Mmus\Plin1, Mmus\Plin4, Mmus\Plin5" "Hsap\PLIN2, Hsap\PLIN4, Hsap\PLIN3, Hsap\PLIN5, Hsap\PLIN1" " larval stage | third instar , embryonic stage | late , embryonic stage | stage 5 , embryonic stage | stage 13 , embryonic stage | stage 4 " " fat body

, fat body && midgut | anterior

, germline cell

, amnioserosa

, organism | ubiquitous " larval stage | third instar fat body

"viable,fertile,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage,visible,partially lethal - majority die,some die during pupal stage" "lipid particle | embryonic stage | maternal effect,fat body,lipid particle,embryonic/larval fat body,nurse cell,lipid particle | embryonic stage,lipid droplet & larval oenocyteppl.PP,mesothoracic tergum" FBgn0000826 png pan gu http://flybase.org/reports/FBgn0000826 FBgn0024363 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719 protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay protein serine/threonine kinase activity ; GO:0004674 | traceable author statement "regulation of mitotic cell cycle ; GO:0007346 | traceable author statement protein phosphorylation ; GO:0006468 | inferred from direct assay egg activation ; GO:0007343 | inferred from mutant phenotype positive regulation of mitotic cell cycle, embryonic ; GO:0045977 | inferred from mutant phenotype" serine/threonine protein kinase complex ; GO:1902554 | inferred from physical interaction with plu "Png, EG:8D8.5, PNG, CG11420, fs(1)M2, pan-gnu, png" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain" CG11420 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-192d15.2, Drer\nek11, Drer\map3k2, Drer\si:ch211-285c6.3, Drer\nek8, Drer\LOC107980443, Drer\si:ch211-217i17.1, Drer\nek12, Drer\nek1, Drer\nek4, Drer\LOC101885992, Drer\si:ch211-285c6.2, Drer\LOC100536894, Drer\map3k3" "Scer\PKH3, Scer\KIN3" "Cele\T07F12.4, Cele\Y106G6A.1" "Xtro\nek5, Xtro\nek3, Xtro\nek9, Xtro\nek8, Xtro\nek4, Xtro\map3k2, Xtro\stkld1, Xtro\nek1, Xtro\map3k3, Xtro\nek10" "Mmus\Nek1, Mmus\Nek3, Mmus\Nek10, Mmus\Nek4, Mmus\Nek8, Mmus\Nek11, Mmus\Nek5, Mmus\Nek9, Mmus\Stkld1" "Hsap\NEK5, Hsap\NEK8, Hsap\NEK3, Hsap\NEK9, Hsap\NEK11, Hsap\NEK4, Hsap\NEK1, Hsap\STKLD1, Hsap\NEK10" " embryonic stage | 0-3 hr , adult stage | female " " egg stage | unfertilized egg , embryonic stage | 0-12 hr " unfertilized egg

"lethal,maternal effect,female sterile,viable,fertile,wild-type,mitotic cell cycle defective,meiotic cell cycle defective" "nuclear chromosome,nucleus,polar body nucleus,nucleus | embryonic stage,nucleus & unfertilized egg,nucleus | blastoderm stage | maternal effect,egg & nucleus,pronucleus,annulate lamellae" FBgn0261988 Gprk2 G protein-coupled receptor kinase 2 http://flybase.org/reports/FBgn0261988 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000239, InterPro:IPR000719, InterPro:IPR000961, InterPro:IPR002290, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement G-protein coupled receptor kinase activity ; GO:0004703 | inferred from mutant phenotype G-protein coupled receptor kinase activity ; GO:0004703 | inferred from sequence or structural similarity" signal transduction ; GO:0007165 | inferred from sequence or structural similarity protein phosphorylation ; GO:0006468 | inferred from mutant phenotype regulation of Toll signaling pathway ; GO:0008592 | inferred from genetic interaction with Tl imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype negative regulation of smoothened signaling pathway ; GO:0045879 | inferred from genetic interaction with fu inferred from genetic interaction with smo inferred from genetic interaction with ptc inferred from genetic interaction with Su(fu) protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity smoothened signaling pathway ; GO:0007224 | inferred from mutant phenotype apical constriction involved in gastrulation ; GO:0003384 | inferred from mutant phenotype regulation of smoothened signaling pathway ; GO:0008589 | inferred from direct assay protein phosphorylation ; GO:0006468 | non-traceable author statement positive regulation of cAMP-mediated signaling ; GO:0043950 | inferred from genetic interaction with Gαi inferred from genetic interaction with Gαs defense response to Gram-positive bacterium ; GO:0050830 | inferred from mutant phenotype regulation of antimicrobial peptide biosynthetic process ; GO:0002805 | inferred from mutant phenotype oocyte morphogenesis ; GO:0048601 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "gprk2, Gprk2, 154978_at, CG17998, Gprk-2, nosh" "IPR000239:GPCR kinase, IPR000719:Protein kinase domain, IPR000961:AGC-kinase, C-terminal, IPR011009:Protein kinase-like domain, IPR016137:RGS domain, IPR017441:Protein kinase, ATP binding site" CG17998 27-Aug-18 DroID_v2018_08 "Drer\grk4, Drer\grk6, Drer\grk1a, Drer\grk1b, Drer\grk7b, Drer\adrbk2, Drer\grk5, Drer\grk5l, Drer\grk7a" - Cele\grk-1 "Xtro\grk5, Xtro\grk7, Xtro\grk1, Xtro\grk4, Xtro\grk6" "Mmus\Grk6, Mmus\Grk4, Mmus\Grk3, Mmus\Grk1, Mmus\Grk2, Mmus\Grk5" "Hsap\GRK4, Hsap\GRK7, Hsap\GRK3, Hsap\GRK2, Hsap\GRK6, Hsap\GRK1, Hsap\GRK5" " larval stage | third instar , oogenesis stage && adult stage | female , embryonic stage | early , embryonic stage " ovary

" oogenesis stage && adult stage | female , larval stage , adult stage , adult stage && oogenesis stage , embryonic stage -- adult stage , larval stage && adult stage " " oocyte

, dorsal mesothoracic disc

, Kenyon cell

, longitudinal connective

, adult head

, larval central nervous system

, larval corpus allatum

, adult central nervous system

,

ubiquitous , optic lobe

, germarium

, follicle cell

, mushroom body

, retina

, mushroom body | restricted

, ovary

, neuron

, mushroom body alpha-lobe

, nurse cell

, ellipsoid body

" DRSC16682 I -1.711341334 -0.622063111 -0.283934963 -0.032537066 0.304681386 0.75792917 FBgn0004893 bowl brother of odd with entrails limited http://flybase.org/reports/FBgn0004893 "FBgn0022034, FBgn0014041" protein_coding_gene "nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from sequence or structural similarity with odd" "embryonic hindgut morphogenesis ; GO:0048619 | inferred from mutant phenotype embryonic pattern specification ; GO:0009880 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from sequence or structural similarity with UniProtKB:P23803 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype embryonic foregut morphogenesis ; GO:0048617 | inferred from mutant phenotype hindgut morphogenesis ; GO:0007442 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from sequence or structural similarity with UniProtKB:P23803 wing disc development ; GO:0035220 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from sequence or structural similarity with UniProtKB:P23803 terminal region determination ; GO:0007362 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from sequence or structural similarity with UniProtKB:P23803 imaginal disc-derived leg joint morphogenesis ; GO:0016348 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from sequence or structural similarity with odd "Bowl, 17-29-5, Su(tor)2-1, l(2)c, org2, CG10021, bowl, BOWL" IPR013087:Zinc finger C2H2-type CG10021 27-Aug-18 DroID_v2018_08 "Drer\klf11a, Drer\klf15, Drer\osr1, Drer\znf148, Drer\egr2b, Drer\znf281b, Drer\egr4, Drer\osr2, Drer\sp2, Drer\si:ch211-117k10.3, Drer\egr1, Drer\znf281a" "Scer\MSN4, Scer\MSN2, Scer\FZF1" "Cele\egrh-3, Cele\odd-1, Cele\egrh-1, Cele\odd-2" "Xtro\egr1, Xtro\egr3, Xtro\klf11, Xtro\sp2, Xtro\klf15, Xtro\egr2, Xtro\osr1, Xtro\osr2" "Mmus\Sp2, Mmus\Egr4, Mmus\Egr3, Mmus\Osr1, Mmus\Osr2, Mmus\Klf11, Mmus\Egr1, Mmus\Klf15" "Hsap\EGR2, Hsap\KLF11, Hsap\EGR4, Hsap\ZBTB4, Hsap\KLF15, Hsap\EGR1, Hsap\OSR2, Hsap\OSR1, Hsap\ZBTB38, Hsap\ZBTB2, Hsap\EGR3, Hsap\SP2" " embryonic stage | stage 5 , embryonic stage , embryonic stage | stage 8-12 , embryonic stage | stage 7-9 , larval stage | third instar , embryonic stage | stage 11 , embryonic stage | stage 8-11 , pupal stage , embryonic stage | stage 7 , embryonic stage | stage 7-12 , embryonic stage | >= 2 hr , embryonic stage | stage 9 , embryonic stage | stage 11-14 " " organism | 80-100% egg length

, organism | pair rule

, posterior embryonic/larval midgut

,

0-10% egg length , amnioproctodeal invagination

, organism | 0-10% egg length

, ventral thoracic disc | restricted

, cephalic furrow

, labral segment

, organism | 80% egg length & ventral

, cephalic furrow | anterior to

, stomodeum

, organism | 70% egg length & dorsal

, embryonic/larval hindgut

,

terminal , leg | restricted

,

segment polarity , anterior embryonic/larval midgut

, embryonic/larval foregut

, organism | 20-100% egg length

" "lethal,recessive,visible,lethal - all die before end of embryonic stage,some die during embryonic stage,female sterile,semidominant,maternal effect,somatic clone,viable" "embryonic mandibular segment,embryonic maxillary segment,embryonic/larval hindgut,embryonic/larval proventriculus,joint,tarsal segment,embryonic large intestine,embryonic small intestine,embryonic rectum,lateral process,cephalopharyngeal skeleton,somatic clone,tarsal segment 2,tarsal segment 3,tarsal segment 4,metatarsus,pretarsus,abdominal 2 ventral denticle belt,abdominal 6 ventral denticle belt,embryonic hindgut,adult cuticle & leg | somatic clone,eye disc,peripodial epithelium & dorsal mesothoracic disc | somatic clone | first instar larval stage,eye-antennal disc,antenna,ectopic,eye,prescutum,embryonic dorsal epidermis,embryonic proventriculus,keyhole structure,sex comb,thorax,chaeta,supernumerary" DRSC00805 E 0.132752495 -0.020690858 0.10548997 -1.875326317 0.192595915 0.752246115 FBgn0028381 Decay Death executioner caspase related to Apopain/Yama http://flybase.org/reports/FBgn0028381 protein_coding_gene cysteine-type endopeptidase activity ; GO:0004197 | traceable author statement cysteine-type endopeptidase activity ; GO:0004197 | inferred from sequence or structural similarity with Dcp-1 inferred from direct assay cysteine-type endopeptidase activity involved in apoptotic process ; GO:0097153 | inferred from biological aspect of ancestor with PANTHER:PTN000047947 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001309, InterPro:IPR002138, InterPro:IPR011600, InterPro:IPR016129 larval midgut histolysis ; GO:0035069 | NOT inferred from mutant phenotype apoptotic process ; GO:0006915 | inferred from mutant phenotype programmed cell death ; GO:0012501 | traceable author statement" cytoplasm ; GO:0005737 | inferred from direct assay "caspase 3, Caspase-3, caspase-3, Decay, CG14902, Drosophila executioner caspase related to Apopain/Yama, DECAY, Casp3, cas3, decay, Cas3, CC3, CAS3, CC-3" "IPR001309:Peptidase C14, p20 domain, IPR002138:Peptidase C14, caspase non-catalytic subunit p10, IPR015917:Peptidase C14A, caspase catalytic domain, IPR016129:Peptidase family C14A, His active site, IPR029030:Caspase-like domain, IPR033139:Peptidase family C14A, cysteine active site, IPR033176:Caspase DECAY" CG14902 27-Aug-18 DroID_v2018_08 "Drer\zgc:171731, Drer\si:dkey-103e21.5, Drer\casp9, Drer\pea15, Drer\LOC101886133, Drer\casp6l1, Drer\casp6, Drer\LOC100331324, Drer\si:ch211-195h23.3, Drer\caspbl, Drer\LOC798445, Drer\casp8l2, Drer\casp8, Drer\casp6l2, Drer\cflara, Drer\casp3b, Drer\casp7, Drer\gbp3, Drer\caspxa, Drer\zgc:194469, Drer\casp2, Drer\caspa, Drer\casp3a, Drer\caspb, Drer\casp8l1" - "Cele\ced-3, Cele\csp-1" "Xtro\pea15, Xtro\casp7, Xtro\casp1, Xtro\casp3, Xtro\casp10, Xtro\casp2, Xtro\casp6, Xtro\casp9, Xtro\LOC733553" "Mmus\Casp7, Mmus\Casp8, Mmus\Casp1, Mmus\Casp6, Mmus\Casp4, Mmus\Casp12, Mmus\Casp3, Mmus\Pycard, Mmus\Casp14, Mmus\Pea15a, Mmus\Casp9, Mmus\Casp2, Mmus\Cflar" "Hsap\CASP7, Hsap\CASP10, Hsap\CASP14, Hsap\CASP4, Hsap\CASP8, Hsap\CARD16, Hsap\CASP2, Hsap\CASP6, Hsap\CARD17, Hsap\CARD8, Hsap\CFLAR, Hsap\PYCARD, Hsap\CASP5, Hsap\PEA15, Hsap\CASP1, Hsap\CASP9, Hsap\CASP3, Hsap\CARD18" " embryonic stage | stage >=13 , larval stage | third instar , embryonic stage | stage 1-7 , adult stage && oogenesis stage , embryonic stage -- adult stage " " embryonic/larval midgut

,

ubiquitous , oocyte

, nurse cell

, eye disc

, larval brain

, egg chamber

, embryonic/larval salivary gland

" "viable,fertile,visible,male semi-sterile" "trichogen cell,male accessory gland,ejaculatory duct,seminal vesicle" DRSC16930 EK -0.227542395 -0.01868415 1.045984036 1.566359268 -0.759995687 1.895748115 FBgn0004369 Ptp99A Protein tyrosine phosphatase 99A http://flybase.org/reports/FBgn0004369 "FBan0002005, FBan0011517, FBgn0010251, FBgn0039661, FBgn0039662, FBgn0040621, FBgn0040622" protein_coding_gene protein tyrosine phosphatase activity ; GO:0004725 | non-traceable author statement protein tyrosine phosphatase activity ; GO:0004725 | inferred from sequence or structural similarity with protein_id:CAA38067.1 transmembrane receptor protein tyrosine phosphatase activity ; GO:0005001 | inferred from sequence or structural similarity protein tyrosine phosphatase activity ; GO:0004725 | inferred from sequence or structural similarity with HGNC:9671 "motor neuron axon guidance ; GO:0008045 | inferred from genetic interaction with Lar, Ptp10D motor neuron axon guidance ; GO:0008045 | inferred from genetic interaction with Ptp69D protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with protein_id:CAA38067.1 protein dephosphorylation ; GO:0006470 | non-traceable author statement axonal defasciculation ; GO:0007414 | traceable author statement defasciculation of motor neuron axon ; GO:0007415 | inferred from genetic interaction with Ptp69D regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype" plasma membrane ; GO:0005886 | inferred from sequence or structural similarity plasma membrane ; GO:0005886 | inferred from direct assay axon ; GO:0030424 | inferred from direct assay "DPTP99A, CT6383, R-PTP 99A, CG11516, CG2005, PTP99A, dptp99A, DPTP[[99A]], CG11515, CG11517, Ptp99A, ptp99A" "IPR000242:PTP type protein phosphatase, IPR000387:Tyrosine specific protein phosphatases domain, IPR003961:Fibronectin type III, IPR016130:Protein-tyrosine phosphatase, active site, IPR003595:Protein-tyrosine phosphatase, catalytic, IPR015943:WD40/YVTN repeat-like-containing domain, IPR029021:Protein-tyrosine phosphatase-like, IPR013783:Immunoglobulin-like fold, IPR007110:Immunoglobulin-like domain" CG11516 27-Aug-18 DroID_v2018_08 "Drer\ptprga, Drer\ptprd, Drer\ptprfa, Drer\ptpn5, Drer\ptpn2b, Drer\ca16c, Drer\ptpn18, Drer\ptprz1b, Drer\ca16b, Drer\ptprr, Drer\ptpn2a, Drer\ptprfb, Drer\ptpn22, Drer\ptprsa, Drer\ptpn1" "Scer\PTP2, Scer\PTP1, Scer\PTP3" "Cele\K07F5.8, Cele\F20H11.4, Cele\C17H12.3, Cele\F10G8.1, Cele\F25H5.7, Cele\T27A3.5, Cele\C55B7.3, Cele\C33H5.16, Cele\C02B10.6, Cele\F38H4.4, Cele\T28F4.3, Cele\ZK616.65, Cele\F47B3.6, Cele\F36H12.10, Cele\egg-3, Cele\C33F10.8, Cele\M04G7.2, Cele\Y48G9A.9, Cele\C46A5.1, Cele\ZK354.8, Cele\Y71F9AL.4, Cele\ptp-4, Cele\F55F8.7, Cele\T22C1.8, Cele\F55H12.5, Cele\F20B6.1, Cele\ptp-3, Cele\ZK484.7, Cele\F36H1.3, Cele\Y39A3A.4, Cele\R10F2.6, Cele\B0207.1, Cele\F47B3.1" "Xtro\ptpn12, Xtro\ptpn22, Xtro\ptpn1, Xtro\ptpn2, Xtro\ptprr, Xtro\ptprz1, Xtro\ptprd, Xtro\ptpn23, Xtro\ptprf, Xtro\ptprs" "Mmus\Ptpn2, Mmus\Ptpn18, Mmus\Ptpn22, Mmus\Ptprc, Mmus\Ptprs, Mmus\Ptprr, Mmus\Ptpn7, Mmus\Ptpn12, Mmus\Ptprd, Mmus\Ptpn20, Mmus\Ptprz1, Mmus\Ptpn5, Mmus\Ptpn23, Mmus\Ptpn1, Mmus\Ptprg, Mmus\Ptprf" "Hsap\PTPN7, Hsap\PTPRD, Hsap\PTPN2, Hsap\PTPN23, Hsap\PTPRF, Hsap\PTPN20, Hsap\PTPN22, Hsap\PTPRR, Hsap\PTPRC, Hsap\PTPN18, Hsap\PTPN1, Hsap\PTPN5, Hsap\PTPN12, Hsap\PTPRG, Hsap\PTPRZ1, Hsap\PTPRS" " larval stage | first instar , embryonic stage | stage 12-14 , embryonic stage , embryonic stage | stage 12 , adult stage , embryonic stage && adult stage , embryonic stage&&adult stage , embryonic stage | stage >=13 , embryonic stage | early , larval stage " " RP1 neuron

, aCC neuron

, central nervous system | restricted

, adult head

, RP2 neuron

, pCC neuron

, VUM neuron

, embryonic central nervous system | segmentally repeated pattern

, imaginal disc

, RP3 neuron

" " embryonic stage | stage 12-16 , embryonic stage | stage 12-17 , embryonic stage | stage >=13 , embryonic stage | stage 12-14 , embryonic stage | stage >=12 , embryonic stage | stage 12 , embryonic stage , embryonic stage | stage 13-17 " " segmental nerve

, longitudinal connective

, intersegmental nerve

, embryonic central nervous system

, posterior commissure

, aCC neuron

, anterior commissure

, commissure

, RP2 neuron

, RP1 neuron

, supraesophageal ganglion

, pCC neuron

, RP3 neuron

, embryonic/larval trachea

, neuron

, ventral nerve cord

, central nervous system | restricted

" "viable,fertile,chemical sensitive" "intersegmental nerve,abdominal segmental nerve" DRSC14319 K 1.916851367 -0.487310118 FBgn0014143 croc crocodile http://flybase.org/reports/FBgn0014143 FBgn0004894 protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001766, InterPro:IPR018122 DNA binding ; GO:0003677 | inferred from direct assay RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN001371846" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001766, InterPro:IPR018122, InterPro:IPR030456 specification of segmental identity, head ; GO:0007380 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "Dmfd1, FD1, fd78E, fd1, CG5069, croc, FoxC" "IPR001766:Fork head domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR018122:Fork head domain conserved site1, IPR030456:Fork head domain conserved site 2" CG5069 27-Aug-18 DroID_v2018_08 "Drer\foxl1, Drer\foxc1a, Drer\foxd1, Drer\foxa1, Drer\foxa2, Drer\foxe1, Drer\foxd2, Drer\foxd3, Drer\zgc:162612, Drer\foxa, Drer\foxa3, Drer\foxc1b, Drer\foxd5, Drer\foxe3" "Scer\HCM1, Scer\FKH1" "Cele\unc-130, Cele\pha-4, Cele\fkh-6, Cele\fkh-2" "Xtro\foxd4l1.1, Xtro\foxd1, Xtro\foxc2, Xtro\foxc1, Xtro\foxi4.2, Xtro\foxe1, Xtro\foxa1, Xtro\foxa2, Xtro\foxd3, Xtro\foxl1, Xtro\foxe3, Xtro\foxa4, Xtro\foxd2" "Mmus\Foxd4, Mmus\Foxd3, Mmus\Foxe1, Mmus\Foxa2, Mmus\Foxl1, Mmus\Foxa3, Mmus\Foxc2, Mmus\Foxd1, Mmus\Foxa1, Mmus\Foxs1, Mmus\Foxc1, Mmus\Foxd2" "Hsap\FOXA1, Hsap\FOXD4L6, Hsap\FOXI3, Hsap\FOXD4L1, Hsap\FOXD4L5, Hsap\FOXE1, Hsap\FOXS1, Hsap\FOXD1, Hsap\FOXD4, Hsap\FOXA2, Hsap\FOXC1, Hsap\FOXD3, Hsap\FOXC2, Hsap\FOXD4L3, Hsap\FOXD4L4, Hsap\FOXL1, Hsap\FOXA3, Hsap\FOXD2" " embryonic stage | blastoderm , embryonic stage | stage 11 , embryonic stage | stage 17 , embryonic stage | stage 7 , embryonic stage | stage 9 , embryonic stage , embryonic stage | stage 7-13 , embryonic stage | stage 5 , embryonic stage | stage 5,6 " " stomodeum

, embryonic/larval pharynx | posterior

, intercalary segment

, mesoderm | posterior | restricted

, embryonic central nervous system

, embryonic/larval foregut

, labral segment

,

posterior | restricted , mesoderm | segmentally repeated

,

anterior | restricted " " embryonic stage | stage 5,6 , embryonic stage | stage 11 , embryonic stage | stage 9 , embryonic stage | stage 17 , embryonic stage | stage 7 , embryonic stage | stage 5 , embryonic stage | stage 7-13 " "

anterior | restricted , mesoderm | segmentally repeated

, mesoderm | posterior | restricted

, embryonic/larval pharynx | posterior

, stomodeum

, labral segment

, intercalary segment

,

posterior | restricted , embryonic/larval foregut

" "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,viable,visible" "embryonic labral segment,embryonic antennal segment,embryonic intercalary segment,embryonic/larval esophagus,stomatogastric nervous system,embryonic/larval labral nerve,adult labral sense organ,dorsopharyngeal organ,pharyngeal monoscolopidial chordotonal organ,trichogen cell" FBgn0028554 x16 x16 splicing factor http://flybase.org/reports/FBgn0028554 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001878 mRNA binding ; GO:0003729 | inferred from direct assay RNA binding ; GO:0003723 | inferred from sequence model protein binding ; GO:0005515 | inferred from physical interaction with Trn-SR mRNA binding ; GO:0003729 | inferred from sequence or structural similarity "regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with HGNC:10785 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 regulation of gene expression ; GO:0010468 | inferred from mutant phenotype RNA splicing ; GO:0008380 | inferred from physical interaction with CG7564, Rbp1, Doa regulation of transcriptional start site selection at RNA polymerase II promoter ; GO:0001178 | inferred from mutant phenotype regulation of mRNA 3'-end processing ; GO:0031440 | inferred from mutant phenotype" precatalytic spliceosome ; GO:0071011 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "9G8, TN166, d9G8, Dxl6, CG10203, X16/9G8, Xl6, RBP1-like, l(2)k00230, 2/30, anon-WO0118547.78, dxl6, xl6, x16, XL6, dx16, Dx16, X16" "IPR000504:RNA recognition motif domain, IPR001878:Zinc finger, CCHC-type" CG10203 27-Aug-18 DroID_v2018_08 "Drer\srsf3b, Drer\srsf7a, Drer\srsf7b, Drer\srsf3a" "Scer\NAB3, Scer\NPL3" "Cele\rsp-6, Cele\Y57G11A.5" "Xtro\srsf3, Xtro\srsf7" "Mmus\Srsf7, Mmus\Srsf3" "Hsap\SRSF3, Hsap\HNRNPC, Hsap\SRSF7" " embryonic stage | stage 11 , embryonic stage | stage 5-11 , larval stage | third instar , embryonic stage | stage 14-16 , adult stage && oogenesis stage " " ventral neurogenic region

,

ubiquitous , eye-antennal disc | restricted

, ventral thoracic disc | restricted

, embryonic brain

, dorsal mesothoracic disc | restricted

, nurse cell

, embryonic central nervous system

" "visible,lethal,recessive,viable,fertile" "eye,trichogen cell" FBgn0025525 bab2 bric a brac 2 http://flybase.org/reports/FBgn0025525 "FBgn0012044, FBgn0035185" protein_coding_gene "AT DNA binding ; GO:0003680 | inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with bip2" "regulation of stem cell differentiation ; GO:2000736 | inferred from mutant phenotype female gonad morphogenesis ; GO:0061040 | inferred from mutant phenotype transcription, DNA-templated ; GO:0006351 | traceable author statement regulation of transcription, DNA-templated ; GO:0006355 | traceable author statement regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001135004 leg disc morphogenesis ; GO:0007478 | inferred from expression pattern eye-antennal disc morphogenesis ; GO:0007455 | inferred from expression pattern" nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | traceable author statement polytene chromosome chromocenter ; GO:0005701 | NOT inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay "bab, bab-II, BAB2, BTB-II, CG13911, CG9102, BtbII, bab2, Bab2, BAB" "IPR000210:BTB/POZ domain, IPR007889:DNA binding HTH domain, Psq-type, IPR011333:SKP1/BTB/POZ domain, IPR009057:Homeobox domain-like" CG9102 27-Aug-18 DroID_v2018_08 - - "Cele\sdz-28, Cele\btb-13" - "Mmus\Nacc2, Mmus\Nacc1" "Hsap\NACC2, Hsap\NACC1, Hsap\ZBTB12" " prepupal stage , larval stage | third instar " " ovary | restricted

, ventral thoracic disc | restricted

" " prepupal stage | stage P1 , prepupal stage , larval stage | third instar stage 2 , larval stage | third instar " " ovary | restricted

, central nervous system | restricted

, larval central nervous system | restricted

, ventral thoracic disc | restricted

, female genital disc | restricted

, male genital disc | restricted

" "visible,dominant,male,body color defective,recessive,female,female sterile,female fertile,partially lethal - majority die,lethal,viable,cell number defective,cell migration defective" "adult cuticle & abdominal segment 5 | male,adult cuticle & abdominal segment 6 | male,leg,ovary,abdominal tergite 5,female,abdominal tergite 6,ovariole,antenna,prothoracic tarsal segment 2,tarsal segment 4,tarsal segment 5,abdominal tergite 7,terminal filament,adult abdominal segment 4,adult abdominal segment 5,adult abdominal segment 6,tergite,adult abdomen & cuticlep339,tarsal segment,wing,adult abdomen & cuticle30A,basal cylinder,arista,ectopic,haltere,wing hinge,wing disc,adult cuticle & abdominal segment | malepnr-MD237,abdominal sternite 6,male,abdominal sternite 7,abdominal sternite 6 & trichome | maleC-765,abdominal tergite 6 & trichome | maleC-765,abdominal sternite 6 & macrochaeta | maleC-765,abdominal tergite 6 & macrochaeta | maleC-765,mesothoracic tergum,terminal filament | prepupal stage,embryonic/larval dorsal vessel" FBgn0029082 hbs hibris http://flybase.org/reports/FBgn0029082 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with sns positive regulation of Notch signaling pathway ; GO:0045747 | inferred from mutant phenotype myoblast fusion ; GO:0007520 | inferred from genetic interaction with sns compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from genetic interaction with rst heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0007157 | inferred from direct assay regulation of striated muscle tissue development ; GO:0016202 | inferred from mutant phenotype inferred from genetic interaction with sns myoblast fusion ; GO:0007520 | traceable author statement establishment of ommatidial planar polarity ; GO:0042067 | inferred from mutant phenotype regulation of striated muscle tissue development ; GO:0016202 | inferred from mutant phenotype compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from mutant phenotype Notch receptor processing ; GO:0007220 | inferred from mutant phenotype positive regulation of endopeptidase activity ; GO:0010950 | inferred from mutant phenotype Malpighian tubule stellate cell differentiation ; GO:0061330 | inferred from expression pattern inferred from mutant phenotype apical plasma membrane ; GO:0016324 | inferred from direct assay endosome ; GO:0005768 | colocalizes_with inferred from direct assay cell-cell adherens junction ; GO:0005913 | inferred from direct assay gamma-secretase complex ; GO:0070765 | colocalizes_with inferred from physical interaction with Psn "Hbs, CT22841, icon, CG7449, hbs" "IPR003006:Immunoglobulin/major histocompatibility complex, conserved site, IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR003961:Fibronectin type III, IPR007110:Immunoglobulin-like domain, IPR013162:CD80-like, immunoglobulin C2-set, IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set" CG7449 27-Aug-18 DroID_v2018_08 "Drer\mybpc2a, Drer\mybpc2b, Drer\nphs1, Drer\myom1a" - "Cele\him-4, Cele\syg-2" "Xtro\LOC100216153, Xtro\nphs1, Xtro\LOC100145501, Xtro\hepacam2" "Mmus\Igfn1, Mmus\Sirpb1a, Mmus\Mybpc1, Mmus\Sirpa, Mmus\Mybpc2, Mmus\Myom3, Mmus\Myom2, Mmus\Nphs1, Mmus\Mybpc3" "Hsap\CD33, Hsap\MYBPC2, Hsap\HMCN2, Hsap\MYBPC3, Hsap\IGFN1, Hsap\NPHS1, Hsap\MYBPC1, Hsap\MYOM2, Hsap\IGSF22, Hsap\SIRPG, Hsap\MYOM3, Hsap\PRODH2" embryonic stage | stage 15 embryonic Malpighian tubule | restricted

"visible,recessive,planar polarity defective,viable,fertile,cell adhesion defective,somatic clone,partially lethal - majority die,some die during pupal stage" "eye,cone cell,microchaeta & adult thorax,interommatidial bristle,supernumerary,somatic clone,photoreceptor cell R3,photoreceptor cell R7,ommatidium,wing margin,notal microchaeta,adult Malpighian tubule Type II cell,presumptive embryonic/larval muscle system,embryonic myoblast,midgut chamber 1,visceral muscle primordium,visceral mesoderm,somatic mesoderm,myoblast,distal,microchaeta & scutumda.G32,microchaeta & scutum-537.4,dorsal,microchaeta & scutumpnr-MD237,inter-ommatidial cell,inter-ommatidial precursor cell,primary pigment cell,septate junction | somatic clone,cell-cell junction | somatic clone,eye photoreceptor cell,inter-ommatidial precursor cell | pupal stage P6,interommatidial bristle | pupal stage P6,wing hair" FBgn0003862 trx trithorax http://flybase.org/reports/FBgn0003862 "FBgn0011040, FBgn0011340, FBgn0011443" protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001628, InterPro:IPR001841, InterPro:IPR001965, InterPro:IPR016569 sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001628 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR001628 histone acetyltransferase activity ; GO:0004402 | contributes_to inferred from direct assay histone methyltransferase activity (H3-K4 specific) ; GO:0042800 | traceable author statement histone methyltransferase activity (H3-K4 specific) ; GO:0042800 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q94545 zinc ion binding ; GO:0008270 | inferred from sequence model chromatin binding ; GO:0003682 | inferred from direct assay protein phosphatase 1 binding ; GO:0008157 | inferred from physical interaction with flw inferred from physical interaction with Pp1-13C inferred from physical interaction with Pp1α-96A inferred from physical interaction with Pp1-87B transcription regulatory region DNA binding ; GO:0044212 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VCH5 protein homodimerization activity ; GO:0042803 | inferred from direct assay" histone H3 acetylation ; GO:0043966 | inferred from mutant phenotype regulation of response to DNA damage stimulus ; GO:2001020 | inferred from genetic interaction with lok histone acetylation ; GO:0016573 | inferred from direct assay histone H3-K4 methylation ; GO:0051568 | inferred by curator from GO:0044665 histone H3-K4 methylation ; GO:0051568 | inferred from direct assay eye development ; GO:0001654 | inferred from mutant phenotype inferred from genetic interaction with UniProtKB:Q9VCH5 axon guidance ; GO:0007411 | inferred from mutant phenotype histone methylation ; GO:0016571 | traceable author statement haltere development ; GO:0007482 | inferred from genetic interaction with UniProtKB:Q9VCH5 positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype histone H3-K4 methylation ; GO:0051568 | inferred from mutant phenotype positive regulation of transcription elongation from RNA polymerase II promoter ; GO:0032968 | inferred from direct assay inferred from mutant phenotype germ cell migration ; GO:0008354 | inferred from mutant phenotype histone methylation ; GO:0016571 | inferred from direct assay germ cell migration ; GO:0008354 | traceable author statement microtubule associated complex ; GO:0005875 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay transcription elongation factor complex ; GO:0008023 | inferred from physical interaction with Sbf MLL1/2 complex ; GO:0044665 | inferred from direct assay histone acetyltransferase complex ; GO:0000123 | inferred from direct assay histone methyltransferase complex ; GO:0035097 | inferred from direct assay "trx, TRX, Trx, CG8651, trx-g, l(3)j14A6, DMTRXIII, trxI and trxII, NR0A5, 4733, 4720, Rg-bx, l(3)s5452, l(3)j3A2, l(3)bx[v], R-bx, Trx-G, tqrx, Trx/MLL, TrX" "IPR001214:SET domain, IPR001628:Zinc finger, nuclear hormone receptor-type, IPR001965:Zinc finger, PHD-type, IPR003616:Post-SET domain, IPR003888:FY-rich, N-terminal, IPR003889:FY-rich, C-terminal, IPR001841:Zinc finger, RING-type, IPR011011:Zinc finger, FYVE/PHD-type, IPR016569:Methyltransferase, trithorax, IPR019787:Zinc finger, PHD-finger, IPR034732:Extended PHD (ePHD) domain, IPR001487:Bromodomain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG8651 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-57f7.7, Drer\kmt2ba, Drer\kmt2bb, Drer\si:ch211-37e10.1, Drer\phf11, Drer\kmt2a, Drer\setbp1" Scer\SET1 "Cele\set-25, Cele\lin-59" "Xtro\kmt2a, Xtro\LOC733724, Xtro\kmt2b" "Mmus\Phf11c, Mmus\Phf11d, Mmus\Phf7, Mmus\Setbp1, Mmus\Gm6904, Mmus\Kmt2b, Mmus\Phf11b, Mmus\Phf11a, Mmus\Kmt2a" "Hsap\SETBP1, Hsap\KMT2B, Hsap\PHF7, Hsap\PHF11, Hsap\KMT2A" " embryonic stage | early , embryonic stage , embryonic stage && larval stage && pupal stage , larval stage | third instar , adult stage | female , embryonic stage | stage 7-9 , embryonic stage | 11-15 hr , adult stage | male , embryonic stage | stage 5 , embryonic stage | 2-4hr , embryonic stage | stage 4 , embryonic stage -- adult stage , pupal stage , embryonic stage | late , embryonic stage | stage 4-8 " " embryonic central nervous system

, dorsal mesothoracic disc | posterior

,

ubiquitous , head

, imaginal disc

, dorsal metathoracic disc | posterior

, mesoderm | presumptive

, mesoderm anlage

, supraesophageal ganglion

, eye-antennal disc

, ventral mesothoracic disc | posterior

,

pair rule , subesophageal ganglion

, antenno-maxillary complex

, ventral nerve cord

,

20-50% egg length , ventral nervous system

, labral segment

, organism | even pair rule

" " larval stage | third instar , embryonic stage , larval stage " " dorsal mesothoracic disc | posterior

, dorsal metathoracic disc | posterior

, embryonic/larval proventriculus

, embryonic/larval salivary gland

, eye-antennal disc

, embryonic/larval midgut

, embryonic/larval digestive system

, ventral mesothoracic disc | posterior

, Malpighian tubule

, embryonic central nervous system

, imaginal disc

, gastric caecum

, larval fat body | central & posterior

" "viable,fertile,lethal,recessive,partially lethal - majority die,visible,lethal - all die before end of larval stage,some die during larval stage,increased cell death,heat sensitive,wild-type,dominant,homeotic,lethal - all die before end of embryonic stage,some die during embryonic stage,non-suppressor of variegation,non-enhancer of variegation,enhancer of variegation,increased cell number,somatic clone,mitotic cell cycle defective,male,partially lethal - majority live,lethal - all die before end of pupal stage,some die during pupal stage,some die during immature adult stage" "adult thorax,wing disc | third instar larval stage,prothoracic tibia,sex comb,prothoracic segment,haltere,metathoracic segment,metathoracic tibia,abdominal tergite 5,male,abdominal tergite 6,abdominal tergite 7,wing,eye,head,labellum,lateral,photoreceptor cell,somatic clone,eye disc,abdominal segment 6,wing vein,ectopic,embryonic/first instar larval cuticle,embryonic/larval brain,embryonic/larval midgut,abdominal segment 5,adult abdominal segment 5,adult abdominal segment 6,adult abdominal segment 7,midgut constriction 1,midgut constriction 2,denticle belt,metathoracic laterotergite,abdominal tergite 2,abdominal tergite 3,antenna,maxillary palpus,adult head,arista,anterior,ventral,ocellar bristle,ocellus,postvertical bristle,pupal cuticle & abdomen,abdominal tergite 1,epiproct,adult,abdominal tergite 4,male genitalia,sternite,spiracle,abdominal segment,gonad,precursor,adult abdominal segment 4,epidermis,embryonic/larval tracheal system,mesothoracic tergum" FBgn0265434 zip zipper http://flybase.org/reports/FBgn0265434 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001609, InterPro:IPR004009 myosin light chain binding ; GO:0032027 | inferred from physical interaction with sqh inferred from physical interaction with Mlc-c motor activity ; GO:0003774 | inferred from sequence or structural similarity with SGD:S000001065 ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity" "mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype dorsal closure ; GO:0007391 | traceable author statement muscle attachment ; GO:0016203 | NOT inferred from genetic interaction with l(2)gl dorsal closure ; GO:0007391 | inferred from genetic interaction with cno, PDZ-GEF maintenance of protein location in cell ; GO:0032507 | inferred from mutant phenotype myosin II filament assembly ; GO:0031036 | inferred from direct assay establishment of neuroblast polarity ; GO:0045200 | traceable author statement dorsal closure ; GO:0007391 | inferred from mutant phenotype myofibril assembly ; GO:0030239 | inferred from mutant phenotype Malpighian tubule morphogenesis ; GO:0007443 | inferred from mutant phenotype anterior midgut development ; GO:0007496 | inferred from mutant phenotype protein oligomerization ; GO:0051259 | inferred from direct assay sarcomere organization ; GO:0045214 | inferred from mutant phenotype ovarian follicle cell migration ; GO:0007297 | traceable author statement dorsal closure, amnioserosa morphology change ; GO:0046664 | inferred from mutant phenotype cuticle pattern formation ; GO:0035017 | inferred from mutant phenotype wound healing ; GO:0042060 | inferred from mutant phenotype head involution ; GO:0008258 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype left/right axis specification ; GO:0070986 | inferred from mutant phenotype regulation of cell cycle ; GO:0051726 | inferred from direct assay dorsal closure, spreading of leading edge cells ; GO:0007395 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype imaginal disc-derived wing hair organization ; GO:0035317 | inferred from genetic interaction with dsh inferred from genetic interaction with fz muscle contraction ; GO:0006936 | inferred from mutant phenotype dorsal closure, leading edge cell differentiation ; GO:0046663 | inferred from mutant phenotype establishment of planar polarity ; GO:0001736 | non-traceable author statement cellular response to mechanical stimulus ; GO:0071260 | inferred from direct assay regulation of tube length, open tracheal system ; GO:0035159 | inferred from mutant phenotype spiracle morphogenesis, open tracheal system ; GO:0035277 | inferred from direct assay regulation of myoblast fusion ; GO:1901739 | inferred from genetic interaction with kirre salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype" cell-cell contact zone ; GO:0044291 | inferred from direct assay apical cortex ; GO:0045179 | colocalizes_with inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay cell cortex ; GO:0005938 | inferred from mutant phenotype apical cortex ; GO:0045179 | traceable author statement cell leading edge ; GO:0031252 | inferred from direct assay myosin II complex ; GO:0016460 | inferred from physical interaction with sqh inferred from physical interaction with Mlc-c cytosol ; GO:0005829 | inferred from direct assay contractile ring ; GO:0070938 | colocalizes_with inferred from direct assay cleavage furrow ; GO:0032154 | inferred from direct assay unconventional myosin complex ; GO:0016461 | inferred from sequence or structural similarity myosin complex ; GO:0016459 | inferred from sequence or structural similarity myosin II complex ; GO:0016460 | inferred from direct assay cytoskeleton ; GO:0005856 | non-traceable author statement Z disc ; GO:0030018 | inferred from direct assay unconventional myosin complex ; GO:0016461 | non-traceable author statement "zip, Zip, CG15792, MyoII, zipper, NMM, Myo-II, myoII, nmMHC, Dm nmII, DmnmII, Myo, nmy-2, E(br), DROMHC, l(2)02957, Dronm-MII, Mhc-c, zpr, anon-WO0140519.37, Mhc-c[1], Myo II, MHC, zip/MyoII, NMMII, Myo-II HC, Myo2, ZIP, l(2)17F1, myo II, Myo15, myosin-II" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR000048:IQ motif, EF-hand binding site, IPR001609:Myosin head, motor domain, IPR002928:Myosin tail, IPR004009:Myosin, N-terminal, SH3-like" CG15792 27-Aug-18 DroID_v2018_08 "Drer\myo5aa, Drer\myo18aa, Drer\LOC103909185, Drer\smyhc2, Drer\myh10, Drer\LOC100537963, Drer\LOC100329748, Drer\wu:fd14a01, Drer\myhb, Drer\myhz1.2, Drer\myh6, Drer\myo5c, Drer\myh11a, Drer\myo5b, Drer\myhz1.1, Drer\ns:zf-e68, Drer\smyhc3, Drer\LOC100333206, Drer\si:dkey-110c1.10, Drer\myhz2, Drer\myh7bb, Drer\LOC100329813, Drer\myh9a, Drer\smyhc1, Drer\myo18ab, Drer\myha, Drer\LOC100333572, Drer\LOC100331349, Drer\myh11b, Drer\vmhc, Drer\myhc4, Drer\myo5ab, Drer\vmhcl, Drer\myh7ba, Drer\myh14, Drer\myh9b" "Scer\MYO4, Scer\MYO1, Scer\MYO2" "Cele\hum-9, Cele\nmy-1, Cele\myo-5, Cele\syd-2, Cele\myo-3, Cele\unc-54, Cele\unc-15, Cele\nmy-2, Cele\myo-2, Cele\myo-6, Cele\myo-1, Cele\hum-2" "Xtro\myh9, Xtro\myo5b, Xtro\myh4, Xtro\myh6, Xtro\myo5a, Xtro\myo18b, Xtro\myh8, Xtro\LOC100493774, Xtro\myh13, Xtro\myh15, Xtro\myh2, Xtro\myh11" "Mmus\Myo18a, Mmus\Myh11, Mmus\Myh14, Mmus\Myh7, Mmus\Myo5b, Mmus\Myh6, Mmus\Myh13, Mmus\Myh7b, Mmus\Myh15, Mmus\Myh8, Mmus\Myh9, Mmus\Myh2, Mmus\Myh1, Mmus\Myh10, Mmus\Myh4, Mmus\Myo5c, Mmus\Myo18b, Mmus\Myh3, Mmus\Myo5a" "Hsap\MYH2, Hsap\MYO5A, Hsap\MYO18A, Hsap\MYH9, Hsap\MYH1, Hsap\MYH15, Hsap\MYH10, Hsap\MYO5C, Hsap\MYO18B, Hsap\MYH11, Hsap\MYH7, Hsap\MYH4, Hsap\MYH8, Hsap\MYH3, Hsap\MYO5B, Hsap\MYH6, Hsap\MYH7B, Hsap\MYH14, Hsap\MYH13" " embryonic stage , embryonic stage && adult stage , embryonic stage | stage 8 " " embryonic central nervous system

, mesoderm

" FBgn0020299 stumps stumps http://flybase.org/reports/FBgn0020299 "FBgn0024898, FBgn0025779, FBgn0028088, FBgn0038245, FBgn0051317, FBgn0063634" protein_coding_gene - "open tracheal system development ; GO:0007424 | non-traceable author statement mesodermal cell migration ; GO:0008078 | traceable author statement fibroblast growth factor receptor signaling pathway ; GO:0008543 | traceable author statement fibroblast growth factor receptor signaling pathway ; GO:0008543 | non-traceable author statement gastrulation ; GO:0007369 | non-traceable author statement epithelial cell migration, open tracheal system ; GO:0007427 | traceable author statement open tracheal system development ; GO:0007424 | inferred from mutant phenotype primary branching, open tracheal system ; GO:0007428 | traceable author statement oogenesis ; GO:0048477 | inferred from mutant phenotype mesoderm migration involved in gastrulation ; GO:0007509 | non-traceable author statement heart development ; GO:0007507 | non-traceable author statement mesoderm development ; GO:0007498 | inferred from expression pattern tracheal outgrowth, open tracheal system ; GO:0007426 | inferred from mutant phenotype morphogenesis of a branching structure ; GO:0001763 | non-traceable author statement glial cell development ; GO:0021782 | inferred from mutant phenotype" intracellular ; GO:0005622 | traceable author statement cytoplasm ; GO:0005737 | traceable author statement cytoplasm ; GO:0005737 | non-traceable author statement "stumps, Hbr, hbr, Dof, CG18485, dof, DOF, dof/hbr/sms, i21, i28, CG3375, Hbr/Dof, stumps/dof, Dof/stumps/heartbroken, dof/hbr, l(3)09904, heartbroken/dof, sms, gene C, P1740, 0837/10, C, l(3)S083710, anon-estC, anon-EST:CL47, CG31317, dof1" "IPR017893:DBB domain, IPR020683:Ankyrin repeat-containing domain" CG31317 27-Aug-18 DroID_v2018_08 Drer\pik3ap1 - - Xtro\pik3ap1 "Mmus\Bank1, Mmus\Pik3ap1" "Hsap\BANK1, Hsap\PIK3AP1" " embryonic stage | stage 11 , embryonic stage , embryonic stage | stage >=11 , embryonic stage | stage 9,10 , embryonic stage | stage >5 , embryonic stage | stage 13 , embryonic stage | stage 4 , embryonic stage | stage 5 , embryonic stage | syncytial blastoderm , embryonic stage | stage 11-12 " " tracheal pit

, embryonic/larval heart

, embryonic/larval tracheal system

, tracheal primordium

, mesoderm

, visceral mesoderm

, mesoderm anlage

, posterior midgut proper primordium

, anterior midgut proper primordium

,

ventral , embryonic glial cell

" " embryonic stage | stage 11 , larval stage | third instar , embryonic stage | stage <11 " " tracheal pit

, mesoderm

dorsal & restricted , dorsal mesothoracic disc && adepithelial cell

, mesoderm

" "lethal,recessive,female sterile,lethal - all die before end of embryonic stage,some die during embryonic stage,cell migration defective,somatic clone,viable" "embryonic/larval trachea,pericardial cell primordium,terminal tracheal cell,somatic clone,embryonic/larval tracheal system,presumptive embryonic salivary gland,tracheal system,embryonic/larval somatic muscle,dorsal,embryonic/larval pericardial cell,cardioblast,somatic mesoderm,visceral mesoderm,mesoderm,egg,presumptive embryonic/larval central nervous system,longitudinal connective,embryonic/larval dorsal vessel,midgut constriction 2,trachea,dorsal vessel primordium,embryonic pericardial cell,dorsal air sac primordium,embryonic/larval dorsal branch,glial cell,subretinal glial cell,somatic clone | third instar larval stage" DRSC15332 E 0.898952777 -1.395533715 0.51074249 -1.595115772 0.081020658 0.982072361 FBgn0004177 mts microtubule star http://flybase.org/reports/FBgn0004177 "FBgn0010514, FBgn0010703, FBgn0031953" protein_coding_gene protein serine/threonine phosphatase activity ; GO:0004722 | non-traceable author statement protein serine/threonine phosphatase activity ; GO:0004722 | inferred from mutant phenotype protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity phosphatase regulator activity ; GO:0019208 | inferred from direct assay centrosome duplication ; GO:0051298 | inferred from mutant phenotype protein dephosphorylation ; GO:0006470 | non-traceable author statement oogenesis ; GO:0048477 | inferred from mutant phenotype chromosome segregation ; GO:0007059 | inferred from mutant phenotype negative regulation of neuroblast proliferation ; GO:0007406 | inferred from mutant phenotype microtubule cytoskeleton organization ; GO:0000226 | inferred from mutant phenotype response to light stimulus ; GO:0009416 | inferred from genetic interaction with inaC regulation of cell shape ; GO:0008360 | inferred from mutant phenotype centrosome cycle ; GO:0007098 | inferred from mutant phenotype protein dephosphorylation ; GO:0006470 | inferred from mutant phenotype positive regulation of smoothened signaling pathway ; GO:0045880 | inferred from genetic interaction with smo inferred from genetic interaction with hh actin filament organization ; GO:0007015 | inferred from mutant phenotype asymmetric neuroblast division ; GO:0055059 | inferred from genetic interaction with l(2)gl inferred from genetic interaction with par-6 spindle organization ; GO:0007051 | inferred from mutant phenotype autophagy ; GO:0006914 | inferred from mutant phenotype canonical Wnt signaling pathway ; GO:0060070 | inferred from mutant phenotype mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype centriole replication ; GO:0007099 | inferred from mutant phenotype centrosome organization ; GO:0051297 | inferred from mutant phenotype establishment of epithelial cell polarity ; GO:0090162 | inferred from expression pattern regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype spindle assembly ; GO:0051225 | inferred from mutant phenotype cell adhesion ; GO:0007155 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype R7 cell fate commitment ; GO:0007465 | inferred from genetic interaction with Ras85D centriole ; GO:0005814 | inferred from direct assay protein phosphatase type 2A complex ; GO:0000159 | inferred from sequence or structural similarity cytoplasm ; GO:0005737 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay "mts, CG7109, PP2A-C, PP2A, PP2A/MTS, PP2, DmPp2A-28D, PP2a, PP2Ac, PP2a 28D, PP2A[[C]], MTS/PP2A, dPP2A, 5559, PP2A 28D, Pp2A-28D, Pp2A, ER2-6, l(2)s5286, l(2)02496, Mts, PP2A C, PP2A[C], dPP2A-C, MTS" "IPR004843:Calcineurin-like phosphoesterase domain, ApaH type, IPR006186:Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase, IPR029052:Metallo-dependent phosphatase-like" CG7109 27-Aug-18 DroID_v2018_08 "Drer\ppp2cb, Drer\ppp4ca, Drer\ppp6c, Drer\ppp2ca, Drer\ppp4cb, Drer\zgc:56064" "Scer\PPH22, Scer\YNL217W, Scer\SIT4, Scer\PPG1, Scer\PPH21, Scer\PPH3" "Cele\pph-4.2, Cele\pph-4.1, Cele\pph-6, Cele\pph-1, Cele\let-92" "Xtro\ppp2cb, Xtro\ppp4c, Xtro\ppp2ca, Xtro\ppp6c" "Mmus\Ppp2ca, Mmus\Ppp6c, Mmus\Ppp4c, Mmus\Ppp2cb" "Hsap\PPP2CB, Hsap\PPP2CA, Hsap\PPP6C" " embryonic stage | early , embryonic stage | late , larval stage | third instar , adult stage && oogenesis stage , embryonic stage -- adult stage , embryonic stage && larval stage , embryonic stage , adult stage , embryonic stage | stage 9-11 , embryonic stage && larval stage && adult stage " " gonad

, embryonic/larval salivary gland

, imaginal disc

, supraesophageal ganglion

, nurse cell

,

ubiquitous , larval brain

, adult brain

, oocyte

, adult midgut

, neuroblast

, ventral nerve cord

" "visible,viable,fertile,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,mitotic cell cycle defective,neuroanatomy defective,planar polarity defective,locomotor rhythm defective,increased cell number,lethal - all die before end of pupal stage,some die during pupal stage,somatic clone" "eye,embryonic/larval hemocyte | third instar larval stage,neuroblast,supernumerary,embryonic/larval brain,wing hair,microtubule & neuromuscular junction | larval stageelav.PLu,bouton & neuromuscular junction | larval stageelav.PLu,embryonic/larval neuroblast,wing margin,type II neuroblast,somatic clone" DRSC03574 IE 0.918009972 -3.40249302 0.404905368 -3.907711575 1.051818802 -0.556150787 FBgn0015777 nrv2 nervana 2 http://flybase.org/reports/FBgn0015777 "FBgn0014867, FBgn0021885, FBgn0022206, FBgn0045319, FBgn0065838" protein_coding_gene sodium:potassium-exchanging ATPase activity ; GO:0005391 | contributes_to inferred from mutant phenotype cation transmembrane transporter activity ; GO:0008324 | contributes_to inferred from direct assay "potassium ion transport ; GO:0006813 | inferred from electronic annotation with InterPro:IPR000402 sodium ion transport ; GO:0006814 | inferred from electronic annotation with InterPro:IPR000402 cell adhesion involved in heart morphogenesis ; GO:0061343 | inferred from mutant phenotype establishment of glial blood-brain barrier ; GO:0060857 | inferred from mutant phenotype regulation of tube length, open tracheal system ; GO:0035159 | inferred from mutant phenotype cation transport ; GO:0006812 | inferred from direct assay regulation of tube diameter, open tracheal system ; GO:0035158 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from mutant phenotype regulation of tube size, open tracheal system ; GO:0035151 | inferred from mutant phenotype septate junction assembly ; GO:0019991 | inferred from mutant phenotype sensory perception of sound ; GO:0007605 | inferred from mutant phenotype" sodium:potassium-exchanging ATPase complex ; GO:0005890 | inferred from electronic annotation with InterPro:IPR000402 septate junction ; GO:0005918 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from sequence or structural similarity sodium:potassium-exchanging ATPase complex ; GO:0005890 | inferred by curator from GO:0005391 axon ; GO:0030424 | inferred from direct assay "Na[+]/K[+] ATPase, Nrv2, NaK ATPase, Na,K-ATPase, Na[+]/K[+]ATPase, Na[+]/K[+]-ATPase, 42kDa, l(2)k04223, l(2)k13315, l(2)SH0329, ecta, NEST:bs13c10, Nrv, CG9261, nrv2, l(2)SH2 0329, nrv2.2, Nrv2.2" IPR000402:Sodium/potassium-transporting ATPase subunit beta CG9261 27-Aug-18 DroID_v2018_08 "Drer\atp1b3a, Drer\atp1b2b, Drer\atp1b2a, Drer\atp1b1a, Drer\atp1b1b, Drer\atp1b3b, Drer\atp1b4" - "Cele\nkb-1, Cele\nkb-3, Cele\nkb-2" "Xtro\atp4b, Xtro\atp1b3, Xtro\atp1b4, Xtro\atp1b2, Xtro\atp1b1" "Mmus\Atp4b, Mmus\Atp1b4, Mmus\Atp1b1, Mmus\Atp1b3, Mmus\Atp1b2" "Hsap\ATP1B3, Hsap\ATP4B, Hsap\ATP1B2, Hsap\ATP1B4, Hsap\ATP1B1" adult stage "

, adult abdomen

, abdomen

, adult head

" " embryonic stage , adult stage , embryonic stage -- adult stage " " embryonic peripheral nervous system

, adult abdomen

, leg

, head

, longitudinal connective

, commissure

, central nervous system

, adult head

, adult brain

, embryonic/larval garland cell

, adult thorax

, embryonic/larval posterior spiracle

, thoracico-abdominal ganglion

, optic lobe

" "lethal,recessive,neuroanatomy defective,viable,visible,auditory perception defective" "septate junction,embryonic/larval dorsal trunk,embryonic/larval transverse connective,embryonic/larval tracheal system,embryonic ganglionic branch & embryonic tracheole,septate junction & embryonic tracheal system,ganglionic branch primordium,dorsal trunk primordium,presumptive embryonic salivary gland,embryonic somatic muscle,tracheal branch primordium,trichogen cell,Johnston organ" FBgn0000769 fs(1)A1059 female sterile (1) A1059 http://flybase.org/reports/FBgn0000769 - gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | traceable author statement cellular_component ; GO:0005575 | no biological data available "fs(1)M60, fs(1)1059, fs(1)K575[ts], fs(1)K575, fs(1)A1059" - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,heat sensitive" FBgn0053814 His2A:CG33814 His2A:CG33814 http://flybase.org/reports/FBgn0053814 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with UniProtKB:Q7L7L0 chromatin organization ; GO:0006325 | inferred from sequence or structural similarity with MGD:Hist1h2aa; MGI:MGI:2448285 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:Q7L7L0 "CG33814, His2A:CG33814" "IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3, IPR002119:Histone H2A, IPR032458:Histone H2A conserved site, IPR032454:Histone H2A, C-terminal domain" CG33814 27-Aug-18 DroID_v2018_08 "Drer\si:ch1073-159d7.11, Drer\si:ch73-368j24.13, Drer\h2afy2, Drer\zgc:101846, Drer\si:ch211-113a14.16, Drer\si:dkey-261m9.11, Drer\si:dkey-23a13.20, Drer\si:ch211-113a14.26, Drer\si:ch1073-159d7.10, Drer\si:ch73-368j24.14, Drer\si:dkey-261m9.18, Drer\h2afx, Drer\si:ch211-113a14.7, Drer\zgc:110434, Drer\si:dkey-261m9.7, Drer\si:dkey-23a13.14, Drer\LOC100334934, Drer\si:ch211-113a14.11, Drer\LOC100332229, Drer\si:dkey-261m9.15, Drer\LOC570115, Drer\si:dkey-108k21.26, Drer\si:ch211-113a14.19, Drer\si:dkey-108k21.15, Drer\zgc:173652, Drer\si:dkey-108k21.19, Drer\si:ch73-36p18.5, Drer\zgc:195633, Drer\zgc:154164, Drer\fbxl6, Drer\LOC100148591, Drer\si:dkey-23a13.7, Drer\zgc:114037" "Scer\HTA2, Scer\HTA1" "Cele\his-65, Cele\his-68, Cele\his-35, Cele\his-47, Cele\his-61, Cele\his-7, Cele\his-33, Cele\his-57, Cele\htas-1, Cele\his-21, Cele\his-30, Cele\his-16, Cele\his-3, Cele\his-19, Cele\his-53, Cele\his-43, Cele\his-51, Cele\his-12" "Xtro\hist1h2aa, Xtro\h2afx, Xtro\hist1h2am, Xtro\h2afj, Xtro\h2afy2, Xtro\hist1h2aj, Xtro\h2afy, Xtro\hist1h2ad, Xtro\hist1h2ah" "Mmus\Hist2h2aa2, Mmus\Hist2h2ab, Mmus\Hist3h2a, Mmus\Hist1h2ao, Mmus\H2afb1, Mmus\Hist2h2ac, Mmus\Hist2h2aa1, Mmus\H2al1n, Mmus\H2afy2, Mmus\Hist1h2ai, Mmus\H2afx, Mmus\H2afb2, Mmus\Gm14920, Mmus\H2al1j, Mmus\H2al2c, Mmus\Hist1h2ak, Mmus\H2al2b, Mmus\H2afj, Mmus\Hist1h2ae, Mmus\Hist1h2ab, Mmus\Hist1h2an, Mmus\Hist1h2ah, Mmus\Hist1h2ag, Mmus\Hist1h2af, Mmus\H2afy, Mmus\Hist2h3c1, Mmus\Hist1h2ad, Mmus\Hist1h2ap, Mmus\Hist1h2ac, Mmus\H2afb3, Mmus\Hist1h2aa" "Hsap\HIST1H2AE, Hsap\HIST2H2AB, Hsap\HIST1H2AK, Hsap\HIST2H2AA3, Hsap\HIST1H2AG, Hsap\HIST1H2AJ, Hsap\H2AFB2, Hsap\HIST1H2AA, Hsap\H2AFY, Hsap\H2AFY2, Hsap\H2AFJ, Hsap\HIST1H2AI, Hsap\HIST1H2AC, Hsap\H2AFB1, Hsap\HIST1H2AH, Hsap\HIST1H2AL, Hsap\HIST1H2AM, Hsap\HIST2H2AA4, Hsap\H2AFX, Hsap\HIST3H2A, Hsap\HIST1H2AB, Hsap\HIST2H2AC, Hsap\H2AFB3, Hsap\HIST1H2AD" FBgn0085259 CG34230 - http://flybase.org/reports/FBgn0085259 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34230 - CG34230 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039882 CG11576 - http://flybase.org/reports/FBgn0039882 protein_coding_gene riboflavin transporter activity ; GO:0032217 | inferred from electronic annotation with InterPro:IPR009357 riboflavin transport ; GO:0032218 | inferred from electronic annotation with InterPro:IPR009357 integral component of plasma membrane ; GO:0005887 | inferred from electronic annotation with InterPro:IPR009357 cytosol ; GO:0005829 | inferred from direct assay CG11576 "IPR009357:Solute carrier family 52, riboflavin transporter" CG11576 27-Aug-18 DroID_v2018_08 "Drer\zgc:91890, Drer\si:ch73-196l6.5, Drer\slc52a3, Drer\slc52a2" - "Cele\rft-2, Cele\rft-1" "Xtro\slc52a1, Xtro\slc52a3" "Mmus\Slc52a2, Mmus\Slc52a3" "Hsap\SLC52A3, Hsap\SLC52A2, Hsap\SLC52A1" "viable,fertile,lethal,partially lethal - majority die,some die during pupal stage" FBgn0067067 Nrt::Wnt2 Nrt::Wnt2 http://flybase.org/reports/FBgn0067067 engineered_fusion_gene - - - Nrt::Wnt2 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0003314 sam sperm amotile http://flybase.org/reports/FBgn0003314 - gene - - - sam - - 27-Aug-18 DroID_v2018_08 - - - - - - male sterile FBgn0060448 l(3)S121612 lethal (3) S121612 http://flybase.org/reports/FBgn0060448 gene - - - "1216/12, l(3)S121612" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0053905 His4:CG33905 His4:CG33905 http://flybase.org/reports/FBgn0053905 protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 histone binding ; GO:0042393 | inferred from sequence or structural similarity with UniProtKB:P62805 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809" "DNA-templated transcription, initiation ; GO:0006352 | inferred from electronic annotation with InterPro:IPR004823 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P62805" "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR001951, InterPro:IPR019809 nucleosome ; GO:0000786 | inferred from sequence or structural similarity with UniProtKB:P62805" "CG33905, His4:CG33905" "IPR019809:Histone H4, conserved site, IPR009072:Histone-fold, IPR001951:Histone H4, IPR004823:TATA box binding protein associated factor (TAF)" CG33905 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-23a13.7, Drer\si:ch211-113a14.26, Drer\si:dkey-108k21.19, Drer\LOC100329358, Drer\si:ch73-36p18.3, Drer\zgc:153409, Drer\LOC794549, Drer\zgc:154164, Drer\si:ch73-368j24.1, Drer\LOC562770, Drer\si:dkey-108k21.28, Drer\si:dkey-261m9.17, Drer\LOC100150038, Drer\si:ch73-368j24.14, Drer\si:dkey-108k21.12, Drer\si:ch73-36p18.4, Drer\hist1h4l, Drer\LOC100331412, Drer\si:ch211-113a14.17, Drer\zgc:194989, Drer\zgc:163040, Drer\LOC570405, Drer\si:ch211-113a14.6, Drer\si:dkey-261m9.18" "Scer\HHF2, Scer\HHF1" "Cele\his-38, Cele\his-31, Cele\his-46, Cele\his-26, Cele\his-28, Cele\his-5, Cele\his-1, Cele\his-14, Cele\his-64, Cele\his-67, Cele\his-56, Cele\his-10, Cele\his-60, Cele\his-50, Cele\his-18, Cele\his-37" "Xtro\LOC100493041, Xtro\hist1h4c, Xtro\LOC101734147, Xtro\hist1h4k" "Mmus\Hist1h4h, Mmus\Hist1h4a, Mmus\Hist1h4b, Mmus\Hist1h4d, Mmus\Hist1h4n, Mmus\Hist1h4m, Mmus\Hist1h4c, Mmus\Hist1h4i, Mmus\Hist4h4, Mmus\Hist1h4k, Mmus\Hist1h4j, Mmus\Hist2h4, Mmus\Hist1h4f" "Hsap\HIST2H4B, Hsap\HIST1H4J, Hsap\HIST1H4D, Hsap\HIST1H4I, Hsap\HIST1H4B, Hsap\HIST1H4E, Hsap\HIST4H4, Hsap\HIST2H4A, Hsap\HIST1H4G, Hsap\HIST1H4H, Hsap\HIST1H4F, Hsap\HIST1H4K, Hsap\HIST1H4C, Hsap\HIST1H4L, Hsap\HIST1H4A" FBgn0264075 tgo tango http://flybase.org/reports/FBgn0264075 protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | contributes_to inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with dysf myosin binding ; GO:0017022 | inferred from physical interaction with Myo10A transcription factor activity, sequence-specific DNA binding ; GO:0003700 | contributes_to inferred from physical interaction with trh RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from sequence or structural similarity with HGNC:700 protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with ss transcription factor activity, sequence-specific DNA binding ; GO:0003700 | contributes_to inferred from physical interaction with sim inferred from physical interaction with dysf inferred from physical interaction with trh protein heterodimerization activity ; GO:0046982 | traceable author statement transcription factor activity, sequence-specific DNA binding ; GO:0003700 | contributes_to inferred from direct assay transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | contributes_to inferred from physical interaction with sim inferred from physical interaction with trh transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | contributes_to inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with sim inferred from physical interaction with sima transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement" "regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from direct assay cellular response to insulin stimulus ; GO:0032869 | inferred from direct assay epithelial cell fate determination, open tracheal system ; GO:0007425 | non-traceable author statement peripheral nervous system development ; GO:0007422 | traceable author statement dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from direct assay limb development ; GO:0060173 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype epithelial cell fate determination, open tracheal system ; GO:0007425 | traceable author statement brain development ; GO:0007420 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | traceable author statement central nervous system development ; GO:0007417 | inferred from mutant phenotype regulation of R7 cell differentiation ; GO:0045676 | inferred from mutant phenotype neuron development ; GO:0048666 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay cellular response to hypoxia ; GO:0071456 | inferred from direct assay glial cell migration ; GO:0008347 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype muscle organ development ; GO:0007517 | inferred from mutant phenotype" "transcription factor complex ; GO:0005667 | inferred from electronic annotation with InterPro:IPR001067 cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR001067 protein complex ; GO:0043234 | inferred from physical interaction with dysf nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:700 nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | inferred by curator from GO:0003700,GO:0043565" "tgo, Tgo, dARNT, dHIF-1beta, Arnt, ARNT, HIF-1beta, Hif1, TGO, DARNT, arnt, Tango, darnt, HIF-1, prd7, HIF1b, CG11987, dTgo, bHLHe4, jay, TGO_CYC, tgo/Arnt, HIF1B/ARNT" "IPR000014:PAS domain, IPR001067:Nuclear translocator, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain, IPR013767:PAS fold" CG11987 27-Aug-18 DroID_v2018_08 "Drer\arnt2, Drer\arnt, Drer\npas4a" - Cele\aha-1 "Xtro\arnt2, Xtro\arnt" "Mmus\Arnt, Mmus\Arnt2" "Hsap\ARNT, Hsap\ARNT2" " embryonic stage | stage 15 , embryonic stage | stage 14 , embryonic stage | <8-12 hr , embryonic stage , oogenesis stage " " embryonic peripheral nervous system

, embryonic maxillary segment

, embryonic antennal segment

, embryonic gnathal segment

, embryonic mandibular segment

, embryonic labial segment

, leg | anlagen

,

ubiquitous " " embryonic stage | stage 15 , embryonic stage | stage 14 , embryonic stage | stage 11-17 , embryonic stage , embryonic stage | stage 11 " " embryonic peripheral nervous system

, embryonic/larval tracheal system

, embryonic maxillary segment

, embryonic mandibular segment

,

ubiquitous , embryonic antennal segment

, dorsal vessel primordium

, supraesophageal ganglion

, embryonic labial segment

, tracheal pit | surrounding

, ventral nerve cord

, embryonic/larval posterior spiracle

" FBgn0086676 spin spinster http://flybase.org/reports/FBgn0086676 protein_coding_gene sphingolipid transporter activity ; GO:0046624 | inferred from biological aspect of ancestor with PANTHER:PTN001160264 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 glial cell differentiation ; GO:0010001 | inferred from mutant phenotype nurse cell apoptotic process ; GO:0045476 | inferred from mutant phenotype glial cell migration ; GO:0008347 | inferred from mutant phenotype negative regulation of decapentaplegic signaling pathway ; GO:0090099 | inferred from genetic interaction with dpp inferred from genetic interaction with sax inferred from genetic interaction with tkv inferred from genetic interaction with Mad oogenesis ; GO:0048477 | inferred from mutant phenotype endosome to lysosome transport ; GO:0008333 | inferred from mutant phenotype lysosome organization ; GO:0007040 | inferred from mutant phenotype cellular response to starvation ; GO:0009267 | inferred from mutant phenotype synaptic vesicle endocytosis ; GO:0048488 | inferred from mutant phenotype regulation of synaptic growth at neuromuscular junction ; GO:0008582 | inferred from mutant phenotype larval central nervous system remodeling ; GO:0035193 | inferred from mutant phenotype regulation of programmed cell death ; GO:0043067 | inferred from mutant phenotype sphingosine-1-phosphate signaling pathway ; GO:0003376 | inferred from biological aspect of ancestor with PANTHER:PTN001160264 endocytosis ; GO:0006897 | inferred from mutant phenotype locomotion ; GO:0040011 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | non-traceable author statement regulation of female receptivity ; GO:0045924 | inferred from mutant phenotype courtship behavior ; GO:0007619 | non-traceable author statement regulation of nurse cell apoptotic process ; GO:0045477 | inferred from mutant phenotype synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype programmed cell death ; GO:0012501 | non-traceable author statement integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011701 vesicle ; GO:0031982 | inferred from direct assay late endosome membrane ; GO:0031902 | inferred from direct assay lysosomal membrane ; GO:0005765 | inferred from biological aspect of ancestor with PANTHER:PTN001160264 "spin, bnch, CG8428, Spin, l(2)k09905, l(2)10403, 25/11, l(2)k02511, l(2R)W5, l(2)W5" "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG8428 27-Aug-18 DroID_v2018_08 "Drer\spns3, Drer\spns2, Drer\spns1" "Scer\VBA5, Scer\HXT2, Scer\HXT10" "Cele\hpo-12, Cele\spin-3, Cele\F47B8.10, Cele\spin-2, Cele\spin-4, Cele\spin-1" "Xtro\spns2, Xtro\spns1" "Mmus\Spns1, Mmus\Spns3, Mmus\Spns2" "Hsap\SPNS1, Hsap\SPNS3, Hsap\SPNS2" FBgn0028979 tio tiptop http://flybase.org/reports/FBgn0028979 protein_coding_gene "nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 chromatin binding ; GO:0003682 | inferred from biological aspect of ancestor with PANTHER:PTN000281113 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001078 | inferred from biological aspect of ancestor with PANTHER:PTN000281113" "negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype epidermis morphogenesis ; GO:0048730 | inferred from mutant phenotype specification of segmental identity, head ; GO:0007380 | inferred from mutant phenotype Malpighian tubule stellate cell differentiation ; GO:0061330 | inferred from expression pattern Malpighian tubule stellate cell differentiation ; GO:0061330 | inferred from genetic interaction with tsh" nucleus ; GO:0005634 | inferred from direct assay "CG12630, tio, Tio" "IPR013087:Zinc finger C2H2-type, IPR027008:Teashirt family, IPR026807:Protein tiptop/teashirt" CG12630 27-Aug-18 DroID_v2018_08 "Drer\tshz1, Drer\tshz3a" - - "Xtro\tshz3, Xtro\tshz2" "Mmus\Tshz1, Mmus\Tshz3, Mmus\Tshz2" "Hsap\TSHZ2, Hsap\TSHZ1, Hsap\TSHZ3" "viable,fertile,visible,homeotic" "antennal disc,eye,ectopic,somatic clone,larval labial segment,T1 beard,denticle,heat sensitive,eye photoreceptor cell,ectopic | third instar larval stage" FBgn0020309 crol crooked legs http://flybase.org/reports/FBgn0020309 "FBgn0010573, FBgn0010685, FBgn0025949, FBgn0025978" protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 "lateral inhibition ; GO:0046331 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype inferred from genetic interaction with if inferred from genetic interaction with mys cell adhesion ; GO:0007155 | inferred from mutant phenotype positive regulation of mitotic cell cycle ; GO:0045931 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from mutant phenotype negative regulation of Wnt signaling pathway ; GO:0030178 | inferred from genetic interaction with arm inferred from genetic interaction with Axn regulation of chromatin silencing ; GO:0031935 | inferred from mutant phenotype heterochromatin organization involved in chromatin silencing ; GO:0070868 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay heterochromatin ; GO:0000792 | inferred from direct assay "CG14938, crol gamma, crol beta, crol alpha, clone 2.48, clone 1.74, anon-EST:Liang-2.48, anon-EST:Liang-1.74, l(2)s2346, l(2)04418, crol, Crol, ORE-15" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG14938 27-Aug-18 DroID_v2018_08 "Drer\znf384l, Drer\znf366, Drer\drl, Drer\znf362b, Drer\si:rp71-1g18.1, Drer\zgc:113220, Drer\vezf1b, Drer\si:dkey-261j4.5, Drer\znf362a, Drer\gtf3aa, Drer\znf983, Drer\zgc:165515, Drer\si:dkey-33c14.6, Drer\si:ch211-119o8.6, Drer\zgc:66448" "Scer\ZAP1, Scer\PZF1, Scer\AZF1" "Cele\eor-1, Cele\lin-29, Cele\fezf-1, Cele\Y55F3AM.14, Cele\ehn-3, Cele\ztf-25, Cele\Y48G8AL.10, Cele\ztf-28, Cele\egl-43, Cele\sem-4, Cele\Y5F2A.4" "Xtro\LOC100489238, Xtro\znf384, Xtro\maz, Xtro\znf217, Xtro\znf362, Xtro\gtf3a, Xtro\vezf1" "Mmus\Gm14139, Mmus\Zfp532, Mmus\Zfp553, Mmus\Zfp820, Mmus\Zfp93, Mmus\Zfp273, Mmus\Gm4724, Mmus\Zfp90, Mmus\Gtf3a, Mmus\Zfp35, Mmus\AI987944, Mmus\Zfp623, Mmus\Zfp442, Mmus\Zkscan7, Mmus\Zfp420, Mmus\Zfp14, Mmus\Gm14322, Mmus\D130040H23Rik, Mmus\0610010B08Rik, Mmus\Zfp715, Mmus\Zfp943, Mmus\Gm6710, Mmus\Zfp981, Mmus\Zfp65, Mmus\Zfp82, Mmus\Gm14325, Mmus\Zfp788, Mmus\Gm14391, Mmus\LOC101056073, Mmus\Zfp689, Mmus\Zfp111, Mmus\Zfp109, Mmus\Gm14305, Mmus\Zfp967, Mmus\Zfp984, Mmus\Zfp182, Mmus\Zfp52, Mmus\Zfp987, Mmus\Zfp119a, Mmus\Zfp105, Mmus\Zfp612, Mmus\Zfp72, Mmus\AW146154, Mmus\Repin1, Mmus\Zfp748, Mmus\Zfp189, Mmus\Zfp119b, Mmus\Zfp112, Mmus\Zfp791, Mmus\Zfp345, Mmus\Zfp729a, Mmus\Zfp51, Mmus\Zfp846, Mmus\Gm10324, Mmus\Zfp37, Mmus\Zfp944, Mmus\Zfp59, Mmus\Zfp27, Mmus\Zfp382, Mmus\Zfp960, Mmus\Zfp968, Mmus\Zfp160, Mmus\Zfp738, Mmus\Zfp28, Mmus\Zfp617, Mmus\Zfp658, Mmus\Zfp933, Mmus\Zfp235, Mmus\Zfp971, Mmus\Zfp992, Mmus\Zfp947, Mmus\Zfp606, Mmus\Zfp11, Mmus\Zkscan16, Mmus\Zfp934, Mmus\Zfp879, Mmus\Zfp458, Mmus\Zfp60, Mmus\Zfp760, Mmus\Zfp2, Mmus\Zfp287, Mmus\Gm14308, Mmus\Zfp473, Mmus\Zfp334, Mmus\Zfp607b, Mmus\Zfp959, Mmus\Gm14124, Mmus\LOC102633156, Mmus\Zfp251, Mmus\Zfp551, Mmus\Zfp758, Mmus\Zfp932, Mmus\Zfp938, Mmus\Zfp808, Mmus\Zfp595, Mmus\Zfp975, Mmus\Zfp974, Mmus\Zfp53, Mmus\Zfp970, Mmus\Zfp366, Mmus\Zfp85, Mmus\Zfp30, Mmus\Zfp994, Mmus\Zfp629, Mmus\Zfp937, Mmus\Zfp930, Mmus\Zfp114, Mmus\Zfp583, Mmus\Zfp87, Mmus\Zfp39, Mmus\Zfp26, Mmus\Zfp872, Mmus\Zfp729b, Mmus\Zfp362, Mmus\Zfp958, Mmus\Zfp819, Mmus\Zfp184, Mmus\4930522L14Rik, Mmus\Vezf1, Mmus\Zfp709, Mmus\Rex2, Mmus\Zfp180, Mmus\Zfp759, Mmus\Zfp605, Mmus\Zfp457, Mmus\Zfp78, Mmus\Zfp873, Mmus\Zfp945, Mmus\Zfp980, Mmus\Gm13212, Mmus\Zfp560, Mmus\Zfp354c, Mmus\Zfp229, Mmus\Zfp677, Mmus\Zfp946, Mmus\Zfp790, Mmus\D3Ertd254e, Mmus\Zfp74, Mmus\Zfp708, Mmus\Zfp985, Mmus\Zfp712, Mmus\Rbak, Mmus\Zfp619, Mmus\Zfp607a, Mmus\Zfp936, Mmus\Gm14326, Mmus\Zfp418, Mmus\Zfp942, Mmus\Zfp341, Mmus\Zfp260, Mmus\Zfp948, Mmus\Maz, Mmus\Zfp54, Mmus\Zfp647, Mmus\Zfp719, Mmus\Zfp976, Mmus\Zfp7, Mmus\Zkscan1, Mmus\Zfp991, Mmus\Zfp40, Mmus\Zfp616, Mmus\Zfp780b, Mmus\Zfp600, Mmus\Gm10778, Mmus\Zfp534, Mmus\Zfp62, Mmus\Zfp799, Mmus\Zfp710, Mmus\Zfp12, Mmus\Zfp451" "Hsap\ZNF93, Hsap\ZNF429, Hsap\ZNF300, Hsap\ZNF737, Hsap\ZNF451, Hsap\ZNF468, Hsap\ZNF92, Hsap\ZNF594, Hsap\ZNF530, Hsap\ZNF132, Hsap\ZNF823, Hsap\ZNF43, Hsap\ZNF34, Hsap\VEZF1, Hsap\ZNF234, Hsap\ZNF233, Hsap\ZNF7, Hsap\ZNF420, Hsap\ZNF441, Hsap\ZFP28, Hsap\ZNF528, Hsap\ZNF586, Hsap\ZNF224, Hsap\ZNF614, Hsap\ZNF382, Hsap\ZNF26, Hsap\ZNF347, Hsap\ZNF433, Hsap\ZNF600, Hsap\ZNF805, Hsap\ZNF606, Hsap\ZNF141, Hsap\ZNF658, Hsap\ZNF418, Hsap\ZNF267, Hsap\ZNF557, Hsap\ZNF160, Hsap\ZNF615, Hsap\ZNF699, Hsap\ZNF543, Hsap\ZNF497, Hsap\ZNF879, Hsap\ZNF136, Hsap\ZNF417, Hsap\ZNF573, Hsap\ZNF480, Hsap\ZNF548, Hsap\ZNF484, Hsap\ZNF354C, Hsap\ZNF384, Hsap\ZNF680, Hsap\ZNF189, Hsap\ZNF776, Hsap\ZNF717, Hsap\ZNF490, Hsap\ZNF85, Hsap\ZNF81, Hsap\ZNF778, Hsap\ZNF560, Hsap\ZNF613, Hsap\ZNF211, Hsap\ZNF814, Hsap\ZNF565, Hsap\ZNF700, Hsap\ZNF732, Hsap\ZNF623, Hsap\ZNF529, Hsap\ZNF362, Hsap\ZNF563, Hsap\ZNF792, Hsap\ZNF510, Hsap\ZNF479, Hsap\ZNF679, Hsap\ZFP62, Hsap\ZNF35, Hsap\ZNF782, Hsap\ZNF630, Hsap\ZNF235, Hsap\ZNF676, Hsap\ZNF366, Hsap\ZNF473, Hsap\ZNF567, Hsap\ZNF98, Hsap\ZNF83, Hsap\ZNF264, Hsap\ZNF790, Hsap\ZNF383, Hsap\ZNF251, Hsap\ZKSCAN7, Hsap\ZNF256, Hsap\ZNF470, Hsap\ZNF799, Hsap\ZNF320, Hsap\ZNF71, Hsap\ZNF729, Hsap\ZNF284, Hsap\ZNF880, Hsap\ZFP2, Hsap\ZNF443, Hsap\ZNF649, Hsap\ZNF273, Hsap\ZNF112, Hsap\ZFP90, Hsap\ZNF229, Hsap\ZNF780A, Hsap\ZNF570, Hsap\ZNF626, Hsap\ZNF527, Hsap\ZNF749, Hsap\ZNF28, Hsap\ZNF45, Hsap\ZNF689, Hsap\ZNF226, Hsap\ZNF599, Hsap\ZNF629, Hsap\ZNF865, Hsap\ZNF583, Hsap\ZNF730, Hsap\ZNF665, Hsap\ZNF791, Hsap\ZNF33A, Hsap\ZNF878, Hsap\ZNF587, Hsap\ZNF222, Hsap\ZNF624, Hsap\ZFP30, Hsap\ZFP14, Hsap\ZNF682, Hsap\ZNF534, Hsap\ZNF91, Hsap\ZNF208, Hsap\ZNF107, Hsap\ZNF416, Hsap\ZNF155, Hsap\ZNF765, Hsap\ZNF257, Hsap\ZNF709, Hsap\ZNF568, Hsap\MAZ, Hsap\ZNF483, Hsap\ZNF431, Hsap\ZNF607, Hsap\ZNF627, Hsap\ZNF585A, Hsap\ZNF460, Hsap\ZNF430, Hsap\ZNF12, Hsap\ZNF44, Hsap\ZNF540, Hsap\ZNF260, Hsap\ZNF841, Hsap\ZNF182, Hsap\ZNF860, Hsap\ZNF611, Hsap\ZNF16, Hsap\ZNF552, Hsap\REPIN1, Hsap\ZNF708, Hsap\ZNF23, Hsap\ZNF117, Hsap\ZNF571, Hsap\ZNF816, Hsap\ZNF20, Hsap\ZNF506, Hsap\ZNF254, Hsap\ZNF701, Hsap\ZNF440, Hsap\ZNF695, Hsap\ZNF180, Hsap\ZNF225, Hsap\ZNF808, Hsap\ZNF845, Hsap\ZNF546, Hsap\ZSCAN26, Hsap\ZNF677, Hsap\ZNF605, Hsap\ZNF569, Hsap\ZNF549, Hsap\ZNF555, Hsap\ZNF331, Hsap\ZNF77, Hsap\ZNF135, Hsap\ZNF84, Hsap\ZNF337, Hsap\ZNF551, Hsap\ZNF850, Hsap\ZNF70, Hsap\ZNF41, Hsap\ZNF780B, Hsap\ZNF461, Hsap\ZNF544, Hsap\ZNF69, Hsap\ZNF195, Hsap\ZSCAN2, Hsap\ZNF33B, Hsap\ZNF184, Hsap\ZNF493, Hsap\ZNF99, Hsap\ZNF175, Hsap\ZNF439, Hsap\ZNF227, Hsap\ZNF716, Hsap\ZNF442, Hsap\ZNF268, Hsap\ZNF79, Hsap\GTF3A, Hsap\ZNF710, Hsap\ZNF616, Hsap\ZNF287, Hsap\ZNF678, Hsap\ZNF763, Hsap\ZNF502, Hsap\ZNF766, Hsap\ZKSCAN1, Hsap\ZNF471, Hsap\ZNF681, Hsap\ZNF250, Hsap\ZNF836, Hsap\ZNF852, Hsap\ZNF223, Hsap\ZNF813, Hsap\ZNF14, Hsap\ZNF304, Hsap\ZNF492, Hsap\ZNF30, Hsap\ZNF714, Hsap\RBAK, Hsap\ZNF675, Hsap\ZNF197" " larval stage | third instar , prepupal stage " "viable,fertile,lethal,recessive,mitotic cell cycle defective,somatic clone,long lived,male limited,starvation stress response defective,temperature response defective,gravitaxis defective,female limited,lethal - all die before end of pupal stage,some die during pupal stage,neuroanatomy defective,visible,increased cell death,cell death defective,partially lethal - majority die" "wing vein,ectopic,ventral thoracic disc,leg,wing,femur,wing pouch,somatic clone,macrochaeta,stage P5 pupa,pupa,adult head,stage P14 pharate adult,metathoracic leg,metathoracic femur,metathoracic leg sensillum,intersegmental nerve,posterior compartment,wing disc,morphogenetic furrow,chaeta,supernumerary,mesothoracic tergum" DRSC21348 K -0.963320905 -0.071652027 -0.315914999 1.041765843 -1.634031783 -1.546821786 FBgn0004378 Klp61F Kinesin-like protein at 61F http://flybase.org/reports/FBgn0004378 "FBgn0004923, FBgn0010911, FBgn0015744" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001752, InterPro:IPR019821 microtubule binding ; GO:0008017 | inferred from direct assay ATP-dependent microtubule motor activity, plus-end-directed ; GO:0008574 | inferred from direct assay motor activity ; GO:0003774 | inferred from direct assay microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity ATP-dependent microtubule motor activity, plus-end-directed ; GO:0008574 | inferred from biological aspect of ancestor with PANTHER:PTN000649234 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P54350" Golgi organization ; GO:0007030 | inferred from mutant phenotype plus-end directed microtubule sliding ; GO:0031535 | inferred from direct assay mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype microtubule-based movement ; GO:0007018 | inferred from direct assay adult chitin-containing cuticle pigmentation ; GO:0048085 | inferred from mutant phenotype mitotic centrosome separation ; GO:0007100 | inferred from mutant phenotype inferred from genetic interaction with ncd protein homotetramerization ; GO:0051289 | inferred from direct assay microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity centrosome separation ; GO:0051299 | inferred from mutant phenotype mitotic spindle assembly ; GO:0090307 | inferred from biological aspect of ancestor with PANTHER:PTN000649235 mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype chromosome segregation ; GO:0007059 | inferred from biological aspect of ancestor with PANTHER:PTN000649235 microtubule bundle formation ; GO:0001578 | inferred from direct assay fusome organization ; GO:0045478 | inferred from mutant phenotype centrosome duplication ; GO:0051298 | inferred from mutant phenotype protein secretion ; GO:0009306 | inferred from mutant phenotype positive regulation of Golgi to plasma membrane protein transport ; GO:0042998 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype fusome ; GO:0045169 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay kinesin complex ; GO:0005871 | inferred from sequence or structural similarity spindle ; GO:0005819 | inferred from direct assay mitotic spindle pole ; GO:0097431 | inferred from direct assay mitotic spindle ; GO:0072686 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from direct assay mitotic spindle microtubule ; GO:1990498 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay aster ; GO:0005818 | inferred from direct assay kinesin complex ; GO:0005871 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay centrosome ; GO:0005813 | colocalizes_with inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay microtubule ; GO:0005874 | inferred from direct assay "KLP61f, klp61f, DmKLP61F, KLP61F, CG9191, DmKlp61F, Klp61F/KRP130, KLP61, 6345, KRP[[130]], KRP130, DmKRP130, urcn, KRP[[(130)]], KLP2, urc, l(3)07012, Krp130, Klp2, Klp61F, CG9191-PA, klp61F, Klp61f, l(3)6D283, l(3)Klp61F, Klp 61F, KIF 8, Kin-5, KIF11" "IPR025901:Kinesin-associated microtubule-binding domain, IPR001752:Kinesin motor domain, IPR019821:Kinesin motor domain, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG9191 27-Aug-18 DroID_v2018_08 "Drer\kif3a, Drer\kif11" "Scer\CIN8, Scer\KIP1" "Cele\klp-20, Cele\bmk-1" Xtro\kif11 "Mmus\Kif11, Mmus\Kif3a" "Hsap\KIF11, Hsap\KIF3A" " embryonic stage && larval stage && pupal stage , adult stage | female , adult stage | male , embryonic stage , embryonic stage | stage 6 " " ovary

, testis

, ventral midline

, ventral nervous system | restricted

, mesoderm anlage

, cephalic furrow

" "viable,fertile,lethal - all die before end of second instar larval stage,recessive,some die during second instar larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,mitotic cell cycle defective,lethal - all die before end of larval stage,some die during larval stage,cytokinesis defective,lethal - all die before end of pupal stage,some die during pupal stage,somatic clone,neuroanatomy defective" "spindle | embryonic stage,spindle | embryonic stage, with Klp61F07012,spermatocyte fusome,nuclear chromosome,embryonic/larval brain,imaginal disc,centriole & spermatocyte,aster & spermatocyte,spindle & spermatocyte,centrosome & spermatocyte,spermatocyte,spermatid,spindle,mitotic cell cycle & spermatocyte,meiotic telophase II & spermatocyte,nuclear lamina & spermatocyte,spindle & neuroblast & larva,nuclear lamina & neuroblast & larva,aster & neuroblast & larva,centrosome & neuroblast & larva,embryonic/larval neuroblast,spindle | pre-blastoderm stage,spindle microtubule | embryonic stage 4,aster & spermatocytebab-PG),spindle & spermatocytebab-PG),centrosome & spermatocytebab-PG),microtubule organizing center | pre-blastoderm stage,spindle | embryonic stage, with Klp61FUbi-p63E.TAvicGFP/Klp61F06836,testis,larval brain & nuclear chromosome & larva,somatic clone,spindle microtubule,astral microtubule,mitosis & nuclear chromosome,spindle pole,S2 cell-line,ganglion mother cell" DRSC08671 IE 1.72234719 -2.332438086 0.869235011 -3.139821157 0.143621329 1.224654645 FBgn0283472 S6k Ribosomal protein S6 kinase http://flybase.org/reports/FBgn0283472 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR000961, InterPro:IPR002290, InterPro:IPR017441, InterPro:IPR017892 ribosomal protein S6 kinase activity ; GO:0004711 | inferred from sequence or structural similarity protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000682064 ribosomal protein S6 kinase activity ; GO:0004711 | inferred from sequence or structural similarity inferred from direct assay protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with Tak1" dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype multicellular organism growth ; GO:0035264 | inferred from mutant phenotype growth ; GO:0040007 | inferred from mutant phenotype response to nutrient ; GO:0007584 | traceable author statement positive regulation of macroautophagy ; GO:0016239 | inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype positive regulation of cell size ; GO:0045793 | non-traceable author statement positive regulation of cell growth ; GO:0030307 | traceable author statement protein phosphorylation ; GO:0006468 | non-traceable author statement actin filament organization ; GO:0007015 | inferred from mutant phenotype positive regulation of cell size ; GO:0045793 | inferred from mutant phenotype positive regulation of organ growth ; GO:0046622 | non-traceable author statement larval feeding behavior ; GO:0030536 | inferred from mutant phenotype synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype positive regulation of growth ; GO:0045927 | traceable author statement protein phosphorylation ; GO:0006468 | inferred from direct assay positive regulation of organ growth ; GO:0046622 | traceable author statement protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity regulation of response to drug ; GO:2001023 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype positive regulation of cell growth ; GO:0030307 | non-traceable author statement phagocytosis ; GO:0006909 | inferred from mutant phenotype somatic muscle development ; GO:0007525 | inferred from mutant phenotype positive regulation of autophagy ; GO:0010508 | inferred from mutant phenotype positive regulation of cell size ; GO:0045793 | traceable author statement myoblast fusion ; GO:0007520 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from genetic interaction with Rheb positive regulation of multicellular organism growth ; GO:0040018 | traceable author statement lipid metabolic process ; GO:0006629 | inferred from mutant phenotype regulation of cell size ; GO:0008361 | traceable author statement oogenesis ; GO:0048477 | inferred from mutant phenotype intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN000682064 positive regulation of cell size ; GO:0045793 | inferred from mutant phenotype inferred from genetic interaction with gig response to oxidative stress ; GO:0006979 | inferred from direct assay regulation of terminal button organization ; GO:2000331 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000682064 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000682064 nucleoplasm ; GO:0005654 | inferred from direct assay presynaptic active zone ; GO:0048786 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "S6k, S6K, dS6K, S6K1, s6k, p70/S6K, CG10539, dS6k, ds6k, s6k11, p70 S6K, DS6K, p70[S6kinase], p70[S6 kinase], fs(3)07084, Dp70s6k, p70s6K, dps6k, dp70s6k, 7084, p70[S6k], p70S6K, Dp70[s6k], Dp70S6k, dp70[S6k], l(3)07084, p70[S6K], 10539, S6k|S6K, 7-10, Pk?6, Pk64F, p-S6K" "IPR000719:Protein kinase domain, IPR000961:AGC-kinase, C-terminal, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR016238:Ribosomal protein S6 kinase, IPR017441:Protein kinase, ATP binding site, IPR017892:Protein kinase, C-terminal" CG10539 27-Aug-18 DroID_v2018_08 "Drer\rps6kal, Drer\sgk2a, Drer\akt2, Drer\rps6ka3a, Drer\stk32a, Drer\rps6ka4, Drer\rps6ka3b, Drer\akt3b, Drer\akt3a, Drer\rps6kb1b, Drer\sgk2b, Drer\sgk1, Drer\rps6ka2, Drer\akt2l, Drer\rps6kb1a, Drer\rps6ka1, Drer\sgk3, Drer\rps6ka5, Drer\si:ch211-195b13.1, Drer\LOC100331306" "Scer\YPK3, Scer\YPK1, Scer\SCH9, Scer\YPK2" "Cele\akt-1, Cele\akt-2, Cele\ceh-93, Cele\rskn-1, Cele\R04A9.7, Cele\sgk-1, Cele\rsks-1, Cele\F28C10.3, Cele\rskn-2" "Xtro\rps6ka1, Xtro\rps6ka2, Xtro\stk32a, Xtro\sgk2, Xtro\sgk1, Xtro\rps6ka4, Xtro\rps6kb1, Xtro\rps6ka6, Xtro\akt1, Xtro\akt2, Xtro\rps6ka3" "Mmus\Rps6ka3, Mmus\Sgk1, Mmus\Stk32b, Mmus\Rps6kb1, Mmus\Rps6ka4, Mmus\Rps6kb2, Mmus\Rps6ka5, Mmus\Rps6ka1, Mmus\Rps6ka6, Mmus\Sgk3, Mmus\Akt3, Mmus\Stk32c, Mmus\Sgk2, Mmus\Akt2, Mmus\Rps6ka2, Mmus\Akt1, Mmus\Stk32a" "Hsap\STK32B, Hsap\RPS6KA3, Hsap\AKT2, Hsap\RPS6KA1, Hsap\RPS6KA6, Hsap\RPS6KB1, Hsap\RPS6KB2, Hsap\SGK2, Hsap\AKT3, Hsap\AKT1, Hsap\STK32A, Hsap\RPS6KA2, Hsap\SGK1, Hsap\SGK3, Hsap\STK32C, Hsap\RPS6KA5, Hsap\RPS6KA4" "viable,small body,visible,neurophysiology defective,partially lethal - majority die,recessive,female sterile,lethal,partially,decreased cell size,lethal - all die before end of larval stage,some die during larval stage,size defective,decreased cell number,wild-type,cell autonomous,somatic clone,neuroanatomy defective,feeding behavior defective,long lived,increased cell number,increased cell size,large body,increased cell growth,chemical resistant,short lived,memory defective,heat sensitive" "segment border muscle,A1-7 dorsal acute muscle 1,embryonic/larval somatic muscle,embryonic myoblast,wing,oocyte,adult,wing & cell | somatic clone,ommatidium,somatic clone,cell | adult stage,wing & cell,wing disc,mitotic cell cycle | somatic clone,eye,larval salivary gland & nucleus,dendrite | somatic clone,dendritic arborizing neuron,embryonic/larval fat body,NMJ bouton,wing blade,salivary gland,trichogen cell" DRSC11276 I -1.527743561 2.457851183 -0.911281262 -1.151322699 0.056746863 0.686103813 FBgn0053866 His3:CG33866 His3:CG33866 http://flybase.org/reports/FBgn0053866 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 nucleosomal DNA binding ; GO:0031492 | inferred from sequence or structural similarity with UniProtKB:P84243 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P84243 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:P84243 "CG33866, His3:CG33866, His3" "IPR000164:Histone H3/CENP-A, IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3" CG33866 27-Aug-18 DroID_v2018_08 "Drer\h3f3b.1, Drer\hist2h3ca1, Drer\si:dkey-108k21.25, Drer\zgc:113983, Drer\si:ch1073-429i10.3, Drer\cenpa, Drer\h3f3c, Drer\hist2h3c, Drer\LOC108190747, Drer\zgc:113984, Drer\LOC108190746, Drer\zgc:173552, Drer\si:ch73-36p18.2, Drer\h3f3d, Drer\h3f3a" "Scer\CSE4, Scer\HHT2, Scer\HHT1" "Cele\his-74, Cele\his-59, Cele\his-13, Cele\his-9, Cele\his-69, Cele\his-40, Cele\his-25, Cele\his-63, Cele\his-27, Cele\his-72, Cele\his-45, Cele\his-17, Cele\his-71, Cele\his-6, Cele\his-2, Cele\his-32, Cele\his-55, Cele\his-42, Cele\his-49" "Xtro\hist2h3d, Xtro\LOC100486113, Xtro\hist2h3c, Xtro\cenpa, Xtro\h3f3b" "Mmus\Hist1h3g, Mmus\Hist2h3c2, Mmus\Hist1h3d, Mmus\Hist1h3b, Mmus\Hist1h3f, Mmus\H3f3b, Mmus\Cenpa, Mmus\Hist2h3b, Mmus\Hist1h3h, Mmus\Hist1h3a, Mmus\Hist1h3i, Mmus\Hist1h3e, Mmus\H3f3a, Mmus\Hist1h3c, Mmus\Hist2h3c1, Mmus\Hist2h2be" "Hsap\H3F3C, Hsap\HIST2H3C, Hsap\HIST1H3B, Hsap\HIST1H3J, Hsap\HIST1H3D, Hsap\HIST2H3A, Hsap\HIST1H3F, Hsap\HIST3H3, Hsap\H3F3B, Hsap\HIST1H3C, Hsap\HIST1H3I, Hsap\H3F3A, Hsap\HIST1H3G, Hsap\CENPA, Hsap\HIST1H3E, Hsap\HIST1H3H, Hsap\HIST1H3A, Hsap\HIST2H3D" FBgn0265726 Nna1 Nna1 carboxypeptidase http://flybase.org/reports/FBgn0265726 protein_coding_gene metallocarboxypeptidase activity ; GO:0004181 | inferred from electronic annotation with InterPro:IPR000834 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000834 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000834 mitochondrion organization ; GO:0007005 | inferred from mutant phenotype larval development ; GO:0002164 | inferred from mutant phenotype neural retina development ; GO:0003407 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from direct assay "CG44533, CG11428, CG32627, CG32628, NnaD, Nna1" "IPR000834:Peptidase M14, carboxypeptidase A" CG44533 27-Aug-18 DroID_v2018_08 "Drer\tpst1l, Drer\tpst1, Drer\agbl2, Drer\agtpbp1, Drer\agbl5" - "Cele\tpst-1, Cele\ccpp-1" "Xtro\agtpbp1, Xtro\agbl2, Xtro\agbl1, Xtro\agbl5" "Mmus\Agtpbp1, Mmus\Agbl1, Mmus\Agbl3, Mmus\Agbl4, Mmus\Tpst1, Mmus\Tpst2, Mmus\Agbl2, Mmus\Agbl5" "Hsap\AGBL3, Hsap\AGBL5, Hsap\AGBL2, Hsap\AGTPBP1, Hsap\AGBL1, Hsap\AGBL4, Hsap\TPST2, Hsap\TPST1" DRSC19404 K -0.17179376 0.465275645 -0.257684559 0.76096315 2.386751242 -0.25729871 FBgn0032162 CG4592 - http://flybase.org/reports/FBgn0032162 protein_coding_gene enoyl-CoA hydratase activity ; GO:0004300 | inferred from biological aspect of ancestor with PANTHER:PTN000941828 fatty acid beta-oxidation ; GO:0006635 | inferred from biological aspect of ancestor with PANTHER:PTN000941828 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000941570 CG4592 "IPR001753:Crotonase superfamily, IPR029045:ClpP/crotonase-like domain" CG4592 27-Aug-18 DroID_v2018_08 Drer\eci1 - - Xtro\eci1 Mmus\Eci1 Hsap\ECI1 viable FBgn0053809 His3:CG33809 His3:CG33809 http://flybase.org/reports/FBgn0053809 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 nucleosomal DNA binding ; GO:0031492 | inferred from sequence or structural similarity with UniProtKB:P84243 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P84243 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:P84243 "CG33809, His3:CG33809" "IPR000164:Histone H3/CENP-A, IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3" CG33809 27-Aug-18 DroID_v2018_08 "Drer\hist2h3ca1, Drer\h3f3b.1, Drer\h3f3a, Drer\zgc:113984, Drer\LOC108190746, Drer\hist2h3c, Drer\cenpa, Drer\LOC108190747, Drer\h3f3d, Drer\si:ch73-36p18.2, Drer\zgc:113983, Drer\zgc:173552, Drer\h3f3c, Drer\si:ch1073-429i10.3" "Scer\HHT1, Scer\HHT2, Scer\CSE4" "Cele\his-49, Cele\his-45, Cele\his-17, Cele\his-59, Cele\his-42, Cele\his-71, Cele\his-27, Cele\his-69, Cele\his-9, Cele\his-55, Cele\his-74, Cele\his-13, Cele\his-2, Cele\his-32, Cele\his-25, Cele\his-6, Cele\his-72, Cele\his-63" "Xtro\cenpa, Xtro\h3f3b, Xtro\hist2h3d" "Mmus\Hist1h3c, Mmus\Hist1h3i, Mmus\H3f3a, Mmus\H3f3b, Mmus\Hist1h3h, Mmus\Cenpa, Mmus\Hist1h3g, Mmus\Hist1h3a, Mmus\Hist1h3b, Mmus\Hist2h3c2, Mmus\Hist1h3e, Mmus\Hist1h3f, Mmus\Hist1h3d, Mmus\Hist2h3b, Mmus\Hist2h3c1" "Hsap\HIST1H3B, Hsap\HIST1H3E, Hsap\HIST1H3I, Hsap\HIST1H3F, Hsap\HIST1H3J, Hsap\CENPA, Hsap\HIST2H3D, Hsap\HIST1H3A, Hsap\HIST3H3, Hsap\HIST1H3D, Hsap\H3F3A, Hsap\H3F3C, Hsap\HIST1H3G, Hsap\HIST1H3C, Hsap\H3F3B, Hsap\HIST2H3A, Hsap\HIST1H3H, Hsap\HIST2H3C" FBgn0003124 polo polo http://flybase.org/reports/FBgn0003124 "FBgn0010758, FBgn0016019, FBgn0027987, FBgn0028177, FBgn0046400" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290 protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity protein kinase activity ; GO:0004672 | non-traceable author statement protein kinase activity ; GO:0004672 | inferred from direct assay protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with gwl" meiotic spindle midzone assembly ; GO:0051257 | inferred from mutant phenotype mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype centrosome organization ; GO:0051297 | inferred from mutant phenotype protein localization ; GO:0008104 | non-traceable author statement oocyte fate commitment ; GO:0048600 | inferred from mutant phenotype sperm aster formation ; GO:0035044 | inferred from mutant phenotype pronuclear migration ; GO:0035046 | inferred from mutant phenotype pronuclear fusion ; GO:0007344 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype inferred from genetic interaction with Map205 mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from direct assay male meiosis ; GO:0007140 | inferred from mutant phenotype embryonic heart tube development ; GO:0035050 | inferred from mutant phenotype cellular protein localization ; GO:0034613 | inferred from mutant phenotype actomyosin contractile ring assembly ; GO:0000915 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement male meiosis cytokinesis ; GO:0007112 | inferred from mutant phenotype spindle assembly involved in female meiosis II ; GO:0007058 | inferred from mutant phenotype male germline ring canal formation ; GO:0030726 | inferred from mutant phenotype attachment of mitotic spindle microtubules to kinetochore ; GO:0051315 | inferred from direct assay astral microtubule nucleation ; GO:0030954 | inferred from mutant phenotype female meiotic division ; GO:0007143 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype negative regulation of neuroblast proliferation ; GO:0007406 | inferred from mutant phenotype female meiosis II ; GO:0007147 | inferred from mutant phenotype midbody ; GO:0030496 | inferred from direct assay spindle pole ; GO:0000922 | inferred from direct assay centriole ; GO:0005814 | inferred from direct assay kinetochore ; GO:0000776 | inferred from direct assay microtubule ; GO:0005874 | inferred from direct assay mitotic spindle midzone ; GO:1990023 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay condensed chromosome outer kinetochore ; GO:0000940 | inferred from direct assay condensed chromosome outer kinetochore ; GO:0000940 | non-traceable author statement spindle ; GO:0005819 | inferred from direct assay nuclear envelope ; GO:0005635 | inferred from direct assay kinetochore microtubule ; GO:0005828 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay centrosome ; GO:0005813 | kinetochore ; GO:0000776 | "polo, Polo, POLO, POLO/PLK1, CG12306, l(3)01673, 1324/08, 0256/04, l(3)77Aa, l(3)S132408, l(3)S025604, anon-WO0172774.3, Polo kinase, PLK1" "IPR000719:Protein kinase domain, IPR000959:POLO box domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR033695:Second polo-box domain, IPR033701:First polo-box domain" CG12306 27-Aug-18 DroID_v2018_08 "Drer\plk2b, Drer\plk1, Drer\plk3, Drer\plk2a, Drer\plk4" Scer\CDC5 "Cele\plk-1, Cele\plk-3, Cele\plk-2" "Xtro\plk2, Xtro\plk1, Xtro\plk3, Xtro\plk4" "Mmus\Plk1, Mmus\Plk5, Mmus\Plk3, Mmus\Plk2, Mmus\Plk4" "Hsap\PLK1, Hsap\PLK2, Hsap\PLK3, Hsap\PLK4" " larval stage && spermatogenesis , embryonic stage -- adult stage , larval stage , embryonic stage | stage 4 , embryonic stage | blastoderm " " testis

, ventral nerve cord

, imaginal disc

, organism | ubiquitous

, larval optic lobe

, larval brain

" embryonic stage "mitotic cell cycle defective,lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,hyperplasia,neuroanatomy defective,increased cell death,lethal - all die before end of pupal stage,some die during pupal stage,viable,sterile,somatic clone,cytokinesis defective,some die during third instar larval stage,female sterile,wild-type,male,meiotic cell cycle defective,female,reduced,cell cycle defective,partially lethal - majority die,partially lethal,maternal effect,some die during embryonic stage,lethal - all die before end of embryonic stage,dominant,visible" "neuroblast & centrosome & larva,testis,primary spermatocyte cyst,onion stage spermatid,Nebenkern,meiotic cell cycle & spindle | male,mitotic cell cycle,mitosis & nuclear chromosome,nuclear chromosome,aster,embryonic/larval cardial cell,neuroblast & larval brain,neuroblast & larval brain | somatic clone,spindle & neuroblast,germarium region 2a,synaptonemal complex,germarium region 3,adult abdomen,tergite,embryonic/larval neuroblast,embryonic/larval brain,macrochaeta,abdomen,germline cyst,meiotic cell cycle | female,polar body nucleus,spermatocyte & spindle,spermatocyte & pericentriolar material,spermatocyte & midbody,spermatid,neuroblast & mitotic anaphase & larva,meiosis II | female,meiotic metaphase II & spindle | female,meiosis II & aster | female,meiosis II & spindle | female,male pronucleus,female pronucleus,meiotic telophase II & contractile ring | female,spindle,centrosome,adult cuticle,germarium region 2b,germarium,type II neuroblast,somatic clone,supernumerary,egg,centrosome | embryonic stage 4,centrosome | embryonic stage 4 | maternal effect,ganglion mother cell,mesothoracic tergum" DRSC22359 EK 1.182863402 0.84616027 -0.441853429 -2.231780857 2.168500088 1.684353783 FBgn0065916 l(2)SH0168 lethal (2) SH0168 http://flybase.org/reports/FBgn0065916 gene - - - "l(2)SH0168, l(2)SH2 0168" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0053880 His2B:CG33880 His2B:CG33880 http://flybase.org/reports/FBgn0053880 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 chromatin assembly or disassembly ; GO:0006333 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 "CG33880, His2B:CG33880" "IPR009072:Histone-fold, IPR000558:Histone H2B, IPR007125:Histone H2A/H2B/H3" CG33880 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-108k21.27, Drer\si:ch211-113a14.11, Drer\si:dkey-23a13.1, Drer\zgc:92591, Drer\zgc:173585, Drer\hist1h2ba, Drer\si:dkey-23a13.5, Drer\si:ch73-368j24.8, Drer\si:ch1073-153i20.3, Drer\ano9a, Drer\si:dkey-23a13.16, Drer\zgc:173587, Drer\si:dkey-261m9.19, Drer\si:ch1073-159d7.13, Drer\LOC100334869, Drer\si:ch73-36p18.3, Drer\hist2h2l, Drer\LOC100334559, Drer\zgc:194989, Drer\zgc:114046, Drer\si:ch1073-159d7.5, Drer\si:ch211-113a14.29, Drer\LOC100329560, Drer\si:dkey-108k21.11, Drer\LOC100329290, Drer\si:dkey-261m9.6, Drer\si:ch211-113a14.28" "Scer\HTB2, Scer\HTB1" "Cele\his-11, Cele\his-41, Cele\his-66, Cele\his-8, Cele\his-22, Cele\his-15, Cele\his-44, Cele\his-54, Cele\his-39, Cele\his-52, Cele\his-20, Cele\his-34, Cele\his-58, Cele\his-4, Cele\his-62, Cele\his-48, Cele\his-29" "Xtro\LOC101734494, Xtro\LOC100485294, Xtro\LOC100498647, Xtro\LOC101731959, Xtro\LOC100496181, Xtro\LOC100498072, Xtro\hist1h2bm, Xtro\LOC101733489, Xtro\LOC100498553, Xtro\hist1h2bk, Xtro\LOC100495041, Xtro\LOC100495396, Xtro\LOC100495578, Xtro\LOC101731067, Xtro\LOC100485134, Xtro\LOC100498329, Xtro\LOC101734862, Xtro\LOC100496445, Xtro\hist1h2bj, Xtro\LOC100486150, Xtro\LOC101735218, Xtro\LOC100495415, Xtro\hist2h2be, Xtro\LOC101730940, Xtro\LOC100496436, Xtro\LOC100497915, Xtro\LOC101733171, Xtro\LOC101735164, Xtro\LOC100492632, Xtro\LOC100486870, Xtro\LOC101733828, Xtro\LOC101731852, Xtro\LOC100497082, Xtro\LOC100487485" "Mmus\Hist2h2be, Mmus\Hist1h2bp, Mmus\Hist1h2bb, Mmus\Hist1h2be, Mmus\Hist3h2ba, Mmus\1700024P04Rik, Mmus\Hist1h2bl, Mmus\Hist1h2bq, Mmus\Hist1h2bk, Mmus\Hist1h2bj, Mmus\Hist2h2bb, Mmus\Hist1h2bm, Mmus\Hist1h2ba, Mmus\Hist1h2bn, Mmus\H2bfm, Mmus\Hist1h2bf, Mmus\Hist1h2bh, Mmus\Hist1h2bc, Mmus\Hist1h2br, Mmus\Hist1h2bg" "Hsap\HIST1H2BM, Hsap\HIST1H2BL, Hsap\HIST2H2BF, Hsap\HIST1H2BC, Hsap\HIST1H2BK, Hsap\H2BFWT, Hsap\HIST1H2BO, Hsap\HIST1H2BA, Hsap\HIST1H2BF, Hsap\H2BFM, Hsap\HIST1H2BH, Hsap\HIST1H2BB, Hsap\HIST1H2BN, Hsap\HIST1H2BJ, Hsap\HIST1H2BG, Hsap\HIST3H2BB, Hsap\HIST1H2BI, Hsap\HIST1H2BE, Hsap\HIST1H2BD, Hsap\HIST2H2BE" FBgn0041188 Atx2 Ataxin-2 http://flybase.org/reports/FBgn0041188 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with tyf short-term memory ; GO:0007614 | NOT inferred from mutant phenotype long-term memory ; GO:0007616 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | inferred from mutant phenotype positive regulation of neuron death ; GO:1901216 | inferred from mutant phenotype chaeta development ; GO:0022416 | inferred from mutant phenotype habituation ; GO:0046959 | inferred from mutant phenotype circadian regulation of translation ; GO:0097167 | inferred from mutant phenotype inferred from physical interaction with tyf oocyte differentiation ; GO:0009994 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype positive regulation of protein binding ; GO:0032092 | inferred from mutant phenotype regulation of synapse structural plasticity ; GO:0051823 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype regulation of cytoplasmic mRNA processing body assembly ; GO:0010603 | inferred from biological aspect of ancestor with PANTHER:PTN000304339 circadian regulation of translation ; GO:0097167 | inferred from genetic interaction with per inferred from genetic interaction with tyf compound eye photoreceptor development ; GO:0042051 | inferred from mutant phenotype stress granule assembly ; GO:0034063 | inferred from biological aspect of ancestor with PANTHER:PTN000304339 negative regulation of gene silencing by miRNA ; GO:0060965 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype regulation of olfactory learning ; GO:0090328 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from expression pattern regulation of actin filament polymerization ; GO:0030833 | inferred from mutant phenotype cytoplasmic stress granule ; GO:0010494 | inferred from biological aspect of ancestor with PANTHER:PTN000304339 cytoplasm ; GO:0005737 | inferred from direct assay "dAtx2, CG5166, SCA2, Datx2, GH27029, dSCA2, Sca2, l(3)06490, atx2, anon-EST:fe2E1, BEST:GH27029, anon-WO0140519.1, anon-WO0118547.351, Atx2, CG5166a, ATX2, Atxain-2, Atx-2, atx-2" "IPR009604:LsmAD domain, IPR025852:Ataxin 2, SM domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR009818:Ataxin-2, C-terminal" CG5166 27-Aug-18 DroID_v2018_08 "Drer\atxn2l, Drer\atxn2" "Scer\PBP1, Scer\AIM3" Cele\atx-2 "Xtro\atxn2l, Xtro\atxn2" "Mmus\Atxn2l, Mmus\Maml1, Mmus\Atxn2" "Hsap\ATXN2L, Hsap\ATXN2" "viable,lethal,recessive,visible,somatic clone,female sterile,germline clone,lethal - all die before end of larval stage,some die during larval stage,increased cell death,uncoordinated,partially lethal - majority die,decreased cell number,conditional,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,circadian behavior defective,learning defective,heat sensitive,locomotor rhythm defective" "eye,somatic clone,ommatidium,nurse cell,germline clone,oocyte,nurse cell & nucleus | germ-line clone,nurse cell & actin filament | germ-line clone,retina,eye disc,border follicle cell,adult thorax & chaeta, with Atx2UAS.cSa, [-],adult thorax & chaeta, with Atx2X1, [-],head,photoreceptor,conditional,embryonic/larval neuroblast" DRSC23010 K -0.179759034 1.948302039 FBgn0000257 car carnation http://flybase.org/reports/FBgn0000257 "FBgn0027357, FBgn0040160" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q24314 syntaxin binding ; GO:0019905 | inferred from physical interaction with Syx16 syntaxin binding ; GO:0019905 | contributes_to inferred from physical interaction with Syx17 SNARE binding ; GO:0000149 | inferred from sequence or structural similarity vesicle docking involved in exocytosis ; GO:0006904 | inferred from electronic annotation with InterPro:IPR001619 endosomal transport ; GO:0016197 | inferred from sequence or structural similarity with SGD:S000004388 protein targeting to lysosome ; GO:0006622 | inferred from mutant phenotype cellular response to starvation ; GO:0009267 | inferred from mutant phenotype eye pigment granule organization ; GO:0008057 | inferred from mutant phenotype endosome to lysosome transport ; GO:0008333 | traceable author statement compound eye pigmentation ; GO:0048072 | inferred from mutant phenotype endosome organization ; GO:0007032 | inferred from mutant phenotype compound eye pigmentation ; GO:0048072 | inferred from genetic interaction with p autophagosome maturation ; GO:0097352 | inferred from mutant phenotype negative regulation of Notch signaling pathway ; GO:0045746 | inferred from mutant phenotype ommochrome biosynthetic process ; GO:0006727 | inferred from mutant phenotype regulation of Notch signaling pathway ; GO:0008593 | inferred from genetic interaction with l(2)gd1 determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity endosome to lysosome transport ; GO:0008333 | inferred from mutant phenotype regulation of protein ubiquitination ; GO:0031396 | inferred from mutant phenotype compound eye pigmentation ; GO:0048072 | traceable author statement endocytosis ; GO:0006897 | inferred from mutant phenotype intracellular transport ; GO:0046907 | traceable author statement Notch receptor processing ; GO:0007220 | inferred from mutant phenotype regulation of SNARE complex assembly ; GO:0035542 | inferred from sequence or structural similarity with SGD:S000004388 membrane ; GO:0016020 | traceable author statement cytosol ; GO:0005829 | traceable author statement CORVET complex ; GO:0033263 | inferred from sequence or structural similarity with SGD:S000004388 HOPS complex ; GO:0030897 | inferred from direct assay lysosome ; GO:0005764 | inferred from direct assay HOPS complex ; GO:0030897 | inferred from mutant phenotype HOPS complex ; GO:0030897 | inferred from sequence or structural similarity with SGD:S000004388 "car, Vps33/carnation, Vps33p, Vps33, Dm-Vps33, l(1)G0447, CG12230, carn, VPS33a, Vps33a, Vps33A, Car" "IPR001619:Sec1-like protein, IPR027121:Vacuolar protein sorting-associated protein 33" CG12230 27-Aug-18 DroID_v2018_08 "Drer\vps33a, Drer\vps33b" Scer\VPS33 "Cele\vps-33.2, Cele\vps-33.1" "Xtro\vps33b, Xtro\vps33a" "Mmus\Vps33a, Mmus\Vps33b" "Hsap\VPS33B, Hsap\VPS33A" "viable,fertile,partially lethal - majority die,recessive,visible,short lived,male,eye color defective,decreased cell death,wild-type,somatic clone,lethal - all die before end of second instar larval stage,some die during second instar larval stage,some die during pupal stage,lethal - all die before end of pupal stage" "eye,late endosome,pigment cell,Malpighian tubule,embryonic/larval brain,endosome,ommatidium,rhabdomere,spermatogonial cyst,male germline cell,somatic clone,rhabdomere | cell autonomous | somatic clone,wing,mesothoracic tergum,embryonic/larval fat body,nutrition conditional,autolysosome | somatic clone | wandering third instar larval stage | nutrition conditionalFRT.RnorCD2.Act5C" FBgn0015247 Diap2 Death-associated inhibitor of apoptosis 2 http://flybase.org/reports/FBgn0015247 - protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 cysteine-type endopeptidase inhibitor activity involved in apoptotic process ; GO:0043027 | inferred from direct assay ubiquitin protein ligase activity ; GO:0061630 | inferred from direct assay caspase binding ; GO:0089720 | inferred from physical interaction with Drice zinc ion binding ; GO:0008270 | inferred from sequence model protein binding ; GO:0005515 | inferred from physical interaction with rpr ubiquitin protein ligase binding ; GO:0031625 | inferred from physical interaction with Diap1 "negative regulation of apoptotic process ; GO:0043066 | inferred from direct assay positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria ; GO:0006964 | inferred from mutant phenotype regulation of cysteine-type endopeptidase activity involved in apoptotic process ; GO:0043281 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype negative regulation of apoptotic process ; GO:0043066 | traceable author statement peptidoglycan recognition protein signaling pathway ; GO:0061057 | inferred from mutant phenotype negative regulation of cysteine-type endopeptidase activity involved in apoptotic process ; GO:0043154 | inferred from genetic interaction with Drice sensory organ development ; GO:0007423 | inferred from mutant phenotype protein ubiquitination ; GO:0016567 | inferred from direct assay negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype protein K48-linked ubiquitination ; GO:0070936 | inferred from direct assay positive regulation of protein import into nucleus, translocation ; GO:0033160 | inferred from mutant phenotype protein K63-linked ubiquitination ; GO:0070534 | inferred from direct assay inhibition of cysteine-type endopeptidase activity involved in apoptotic process ; GO:1990001 | inferred from biological aspect of ancestor with PANTHER:PTN000799330 negative regulation of apoptotic process ; GO:0043066 | inferred from sequence or structural similarity regulation of signal transduction ; GO:0009966 | inferred from biological aspect of ancestor with PANTHER:PTN000005165 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process ; GO:0043154 | inferred from direct assay protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000799330 perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay "CG8293, DIAP2, DIAPII, diap2, Diap2, DIAP-2, DIAP, dIAP2, IAP, dIAP, DIHA, D-IAP2, dILP, D-iap2, Ilp, Diha, Diap, IAP2, Iap2, Diap-2" "IPR001370:BIR repeat, IPR001841:Zinc finger, RING-type" CG8293 27-Aug-18 DroID_v2018_08 "Drer\mylipb, Drer\birc7, Drer\birc5b, Drer\birc5a, Drer\birc6, Drer\xiap, Drer\birc2" Scer\BIR1 "Cele\K11D12.9, Cele\bir-1, Cele\bir-2" "Xtro\birc2, Xtro\birc7, Xtro\birc5.2, Xtro\xiap, Xtro\nlrc4, Xtro\birc5.1, Xtro\birc6" "Mmus\Naip2, Mmus\Birc7, Mmus\Nlrc4, Mmus\Naip1, Mmus\Birc6, Mmus\Birc5, Mmus\Xiap, Mmus\Birc2, Mmus\Naip6, Mmus\Naip7, Mmus\Naip5, Mmus\Birc3" "Hsap\NAIP, Hsap\XIAP, Hsap\BIRC8, Hsap\BIRC7, Hsap\BIRC3, Hsap\BIRC5, Hsap\MYLIP, Hsap\NLRC4, Hsap\BIRC2, Hsap\BIRC6" embryonic stage&&larval stage&&adult stage "lethal - all die before end of pupal stage,some die during pupal stage,immune response defective,visible,body color defective,partially lethal - majority die,viable,radiation sensitive,cell death defective,conditional,fertile,increased cell death,chemical sensitive" "macrochaeta,supernumerary,trichogen cell,mesothoracic tergum,wing disc,eye,pigment cell" FBgn0029157 ssh slingshot http://flybase.org/reports/FBgn0029157 protein_coding_gene protein tyrosine phosphatase activity ; GO:0004725 | inferred from electronic annotation with InterPro:IPR016130 actin binding ; GO:0003779 | inferred from biological aspect of ancestor with PANTHER:PTN000016922 phosphoprotein phosphatase activity ; GO:0004721 | inferred from direct assay MAP kinase tyrosine/serine/threonine phosphatase activity ; GO:0017017 | NOT inferred from direct assay protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | non-traceable author statement actin binding ; GO:0003779 | inferred from direct assay regulation of axonogenesis ; GO:0050770 | inferred from mutant phenotype negative regulation of actin filament polymerization ; GO:0030837 | inferred from direct assay protein dephosphorylation ; GO:0006470 | non-traceable author statement regulation of axonogenesis ; GO:0050770 | inferred from genetic interaction with sick protein dephosphorylation ; GO:0006470 | inferred from mutant phenotype mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from genetic interaction with mbt regulation of actin polymerization or depolymerization ; GO:0008064 | inferred from mutant phenotype axonogenesis ; GO:0007409 | inferred from mutant phenotype regulation of actin filament polymerization ; GO:0030833 | inferred from mutant phenotype cell morphogenesis ; GO:0000902 | inferred from mutant phenotype establishment of nucleus localization ; GO:0040023 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype regulation of lamellipodium assembly ; GO:0010591 | inferred from mutant phenotype cytoskeleton ; GO:0005856 | inferred from electronic annotation with InterPro:IPR027232 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000016922 apical part of cell ; GO:0045177 | inferred from direct assay "Ssh, MKP, CG6238, Mkph, l(3)01207, ssh, SSH" "IPR000340:Dual specificity phosphatase, catalytic domain, IPR000387:Tyrosine specific protein phosphatases domain, IPR014876:DEK, C-terminal, IPR016130:Protein-tyrosine phosphatase, active site, IPR020422:Dual specificity protein phosphatase domain, IPR024950:Dual specificity phosphatase, IPR027232:Protein phosphatase Slingshot, IPR029021:Protein-tyrosine phosphatase-like" CG6238 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-175m17.7, Drer\dusp22a, Drer\styx, Drer\dusp2, Drer\dusp19b, Drer\LOC100150565, Drer\dusp13a, Drer\dusp6, Drer\ssh2a, Drer\dusp8b, Drer\dusp16, Drer\dupd1, Drer\dusp14, Drer\si:ch1073-184j22.2, Drer\dusp1, Drer\dusp22b, Drer\dusp7, Drer\dusp4, Drer\dusp3a, Drer\dusp8a, Drer\ssh1b, Drer\ssh2b, Drer\si:ch211-121a2.2, Drer\dusp5, Drer\dusp3b, Drer\dusp10, Drer\si:ch211-195b15.8, Drer\si:ch211-203d1.3, Drer\zgc:153044, Drer\dusp12, Drer\ssh1a, Drer\styxl1, Drer\dusp27, Drer\LOC100538052, Drer\si:ch211-223p8.8, Drer\dusp28, Drer\dusp19a, Drer\zgc:153981" "Scer\YVH1, Scer\MSG5, Scer\SDP1, Scer\PPS1" "Cele\vhp-1, Cele\Y54F10BM.13, Cele\lip-1, Cele\F13D11.3, Cele\C04F12.8, Cele\F26A3.4" "Xtro\dusp10, Xtro\dusp28, Xtro\dusp22, Xtro\dusp6, Xtro\epm2a, Xtro\dupd1, Xtro\dusp4, Xtro\ssh1, Xtro\dusp12, Xtro\styxl1, Xtro\styx, Xtro\dusp9, Xtro\dusp18, Xtro\ssh2, Xtro\dusp26, Xtro\dusp5, Xtro\dusp19, Xtro\dusp1, Xtro\dusp22a" "Mmus\Dusp18, Mmus\Ssh2, Mmus\Dusp10, Mmus\Dusp22, Mmus\Dusp9, Mmus\Dusp28, Mmus\Dupd1, Mmus\Dusp1, Mmus\Dusp12, Mmus\Dusp3, Mmus\Ssh1, Mmus\Dusp16, Mmus\Dusp26, Mmus\Dusp6, Mmus\Ssh3, Mmus\Dusp27, Mmus\Dusp4, Mmus\Dusp8, Mmus\Dusp14, Mmus\Dusp7, Mmus\Epm2a, Mmus\Dusp19, Mmus\Dusp21, Mmus\Dusp2, Mmus\Dusp5, Mmus\Dusp15, Mmus\Styx, Mmus\Styxl1, Mmus\Dusp13" "Hsap\DUSP26, Hsap\DUSP2, Hsap\DUPD1, Hsap\STYX, Hsap\DUSP22, Hsap\EPM2A, Hsap\DUSP7, Hsap\DUSP3, Hsap\DUSP8, Hsap\DUSP5, Hsap\DUSP15, Hsap\DUSP10, Hsap\DUSP9, Hsap\DUSP18, Hsap\DUSP6, Hsap\DUSP1, Hsap\STYXL1, Hsap\DUSP13, Hsap\DUSP4, Hsap\DUSP14, Hsap\DUSP21, Hsap\SSH3, Hsap\DUSP27, Hsap\SSH2, Hsap\DUSP16, Hsap\DUSP19, Hsap\SSH1, Hsap\DUSP12" "lethal,recessive,visible,somatic clone,maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "denticle belt,embryonic/first instar larval cuticle,eye,somatic clone,maternal effect,ommatidium,rhabdomere,adult mushroom body & axon | somatic clone,medial branch of mushroom body,optic lobe neuron & axon | somatic clone,antennal lobe & axon | somatic clone,vertical lobe of adult mushroom body,filamentous actin & ommatidial cluster | ectopic | somatic clone,nucleus & ommatidial cluster | somatic clone,apical junction complex & ommatidial cluster | somatic clone,wing hair,macrochaeta & mesothoracic tergum | somatic clone,actin filament | cell autonomous | ectopic | somatic clone,filamentous actin | somatic clone,medial lobe of adult mushroom body" DRSC16730 K 0.360154131 0.621323091 -0.0240727 0.206665041 1.815135056 1.285103886 FBgn0001961 Arpc1 "Actin-related protein 2/3 complex, subunit 1" http://flybase.org/reports/FBgn0001961 - protein_coding_gene structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity with HGNC:704 actin binding ; GO:0003779 | inferred from sequence or structural similarity actin filament binding ; GO:0051015 | inferred from biological aspect of ancestor with PANTHER:PTN000076207 cell adhesion mediated by integrin ; GO:0033627 | inferred from mutant phenotype chaeta development ; GO:0022416 | inferred from mutant phenotype actin filament-based process ; GO:0030029 | inferred from mutant phenotype Arp2/3 complex-mediated actin nucleation ; GO:0034314 | inferred from biological aspect of ancestor with PANTHER:PTN000076207 pseudocleavage involved in syncytial blastoderm formation ; GO:0030589 | inferred from mutant phenotype intracellular protein transport ; GO:0006886 | inferred from mutant phenotype axonal fasciculation ; GO:0007413 | inferred from genetic interaction with Arp3 compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype positive regulation of filopodium assembly ; GO:0051491 | inferred from mutant phenotype epithelium development ; GO:0060429 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype cell morphogenesis ; GO:0000902 | inferred from mutant phenotype positive regulation of Notch signaling pathway ; GO:0045747 | inferred from mutant phenotype cytoskeleton organization ; GO:0007010 | inferred from sequence or structural similarity actin filament reorganization involved in cell cycle ; GO:0030037 | inferred from mutant phenotype axonogenesis ; GO:0007409 | inferred from genetic interaction with Arp3 negative regulation of dendrite morphogenesis ; GO:0050774 | inferred from mutant phenotype Arp2/3 complex-mediated actin nucleation ; GO:0034314 | inferred from sequence or structural similarity with HGNC:704 detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype Arp2/3 protein complex ; GO:0005885 | inferred from sequence or structural similarity with HGNC:704 Arp2/3 protein complex ; GO:0005885 | non-traceable author statement Arp2/3 protein complex ; GO:0005885 | traceable author statement "ArcP41, sop2, Arpc1, ARPC1, l(2)34Dd, ARPC1/p41, Spo2, Dsop2, CG8978, ARC-P41, sop2/arc41, l(2)Sop2, arc41, BG:DS00941.7, p42, 34Dd, br32, l(2)br32, DSop2, Sop2, D-sop2, Arc41, ArpC1, arpc1, sop, p41" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain, IPR001680:WD40 repeat, IPR017383:Actin-related protein 2/3 complex subunit 1" CG8978 27-Aug-18 DroID_v2018_08 "Drer\arpc1b, Drer\arpc1a, Drer\zgc:86896" Scer\ARC40 Cele\arx-3 "Xtro\arpc1a, Xtro\arpc1b" "Mmus\Arpc1b, Mmus\Arpc1a" "Hsap\ARPC1A, Hsap\ARPC1B" oogenesis stage | stage S9 ring canal

"lethal,recessive,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,supernumerary,mesothoracic tergum,nurse cell,germline clone,follicle cell,somatic clone,epithelium,female germline cyst,filopodium,nurse cell ring canal,actin filament & nurse cell | germ-line clone,nucleus & nurse cell | germ-line clone,tormogen cell,macrochaeta,eye,ommatidium,lens,interommatidial bristle,macrochaeta & adult head | somatic clone,microchaeta & adult head | somatic clone,rhabdomere | adult stage | somatic clone,photoreceptor,retina,cell cycle | germline clone,metaphase & condensed nuclear chromosome | germ-line clone,centrosome | ectopic | germline clone,actin filament | germline clone,oocyte,nucleus | embryonic stage 4 | germline clone | non-rescuable maternal effect,actin filament | embryonic stage 4 | germline clone | non-rescuable maternal effect,nurse cell & actin filament | germ-line clone,anterior dorsocentral bristle,myoblast,mechanosensory chaeta,external sensory organ precursor cell IIa,external sensory organ precursor cell IIb,wing" FBgn0020510 Abi Abelson interacting protein http://flybase.org/reports/FBgn0020510 - protein_coding_gene "protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:B1Q236,UniProtKB:P55162,UniProtKB:Q8MLQ0,UniProtKB:Q9VF87,UniProtKB:Q9VKM2 protein binding ; GO:0005515 | inferred from physical interaction with Abl protein binding ; GO:0005515 | inferred from physical interaction with Ptp61F protein binding ; GO:0005515 | inferred from physical interaction with ena protein binding ; GO:0005515 | inferred from physical interaction with Hem inferred from physical interaction with WASp" regulation of actin cytoskeleton organization ; GO:0032956 | inferred from mutant phenotype photoreceptor cell axon guidance ; GO:0072499 | inferred from mutant phenotype actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype Golgi organization ; GO:0007030 | inferred from mutant phenotype axon extension involved in axon guidance ; GO:0048846 | inferred from mutant phenotype muscle attachment ; GO:0016203 | inferred from mutant phenotype cell adhesion ; GO:0007155 | inferred from mutant phenotype neuromuscular junction development ; GO:0007528 | inferred from genetic interaction with Abl phagocytosis ; GO:0006909 | inferred from mutant phenotype positive regulation of protein kinase activity ; GO:0045860 | inferred from direct assay cell adhesion mediated by integrin ; GO:0033627 | inferred from mutant phenotype positive regulation of cytoskeleton organization ; GO:0051495 | inferred from mutant phenotype cortical actin cytoskeleton organization ; GO:0030866 | inferred from mutant phenotype lamellipodium assembly ; GO:0030032 | inferred from mutant phenotype cell projection assembly ; GO:0030031 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype chaeta development ; GO:0022416 | inferred from mutant phenotype cell morphogenesis ; GO:0000902 | inferred from mutant phenotype central nervous system neuron axonogenesis ; GO:0021955 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype "SCAR complex ; GO:0031209 | inferred from direct assay lamellipodium membrane ; GO:0031258 | inferred from direct assay protein complex ; GO:0043234 | colocalizes_with inferred from physical interaction with WASp basal part of cell ; GO:0045178 | inferred from direct assay perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay SCAR complex ; GO:0031209 | colocalizes_with inferred from physical interaction with Hem, SCAR" "dAbi, Abi-1, CG9749, Ablphilin, Abi, abi" "IPR001452:SH3 domain, IPR012849:Abl-interactor, homeo-domain homologous domain, IPR028457:ABI family" CG9749 27-Aug-18 DroID_v2018_08 "Drer\abi3a, Drer\abi1b, Drer\abi2a, Drer\abi3b, Drer\abi2b, Drer\abi1a" - "Cele\abi-1, Cele\nck-1" "Xtro\abi2, Xtro\abi1" "Mmus\Abi3, Mmus\Abi2, Mmus\Abi1" "Hsap\ABI2, Hsap\ABI3, Hsap\ABI1" "neuroanatomy defective,recessive,lethal - all die before end of P-stage,some die during P-stage,visible,maternal effect,lethal - all die before end of pupal stage,some die during pupal stage,lethal,lethal - all die before end of embryonic stage,germline clone,some die during embryonic stage,cell shape defective,viable" "outer photoreceptor cell,tract,lamina,medulla,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,somatic clone,dorsocentral bristle,scutellar bristle,chaeta,sensory mother cell,longitudinal connective,maternal effect,filamentous actin | ectopicen-e16E,notopleural bristle,supernumerary,chaeta & mesothoracic tergum | ectopic-537.4,presumptive embryonic/larval nervous system" DRSC14099 K -0.025477939 -0.365066553 -0.494653164 -0.285618757 1.813661836 0.138283321 FBgn0020416 Idgf1 Imaginal disc growth factor 1 http://flybase.org/reports/FBgn0020416 FBgn0027915 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR011583 imaginal disc growth factor receptor binding ; GO:0008084 | inferred from direct assay "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR001223, InterPro:IPR013781 chitin-based cuticle development ; GO:0040003 | inferred from mutant phenotype imaginal disc development ; GO:0007444 | inferred from direct assay wound healing ; GO:0042060 | inferred from mutant phenotype ecdysis, chitin-based cuticle ; GO:0018990 | inferred from mutant phenotype" extracellular region ; GO:0005576 | non-traceable author statement "IDGF, IDGF1, IDGF-1, CG4472, idgf1, BG:DS02780.5, Idgf1, ldgf1, DmIDGF1" "IPR001223:Glycoside hydrolase family 18, catalytic domain, IPR011583:Chitinase II, IPR017853:Glycoside hydrolase superfamily, IPR029070:Chitinase insertion domain" CG4472 27-Aug-18 DroID_v2018_08 "Drer\chia.5, Drer\ovgp1, Drer\chia.4, Drer\chia.6, Drer\si:ch211-226m16.2, Drer\chia.3, Drer\chia.2" Scer\CTS2 "Cele\cht-2, Cele\chil-23, Cele\chil-12, Cele\chil-4, Cele\chil-22, Cele\chil-13, Cele\T19H5.6, Cele\chil-25, Cele\chil-3, Cele\chil-2, Cele\chil-7, Cele\chil-15, Cele\lmd-5, Cele\chil-6, Cele\chil-5, Cele\chil-20, Cele\chil-18, Cele\chil-8, Cele\chil-16, Cele\chil-17, Cele\chil-24, Cele\chil-19, Cele\chil-11, Cele\lmd-4" "Xtro\ctbs, Xtro\chia, Xtro\LOC548945, Xtro\chit1" "Mmus\Chil1, Mmus\Chil6, Mmus\Ovgp1, Mmus\Chil3, Mmus\Chil5, Mmus\Chit1, Mmus\Chia1, Mmus\Chil4, Mmus\Ctbs" "Hsap\CHIT1, Hsap\CHIA, Hsap\OVGP1, Hsap\CHI3L1, Hsap\CHI3L2" " embryonic stage , larval stage | third instar , adult stage && oogenesis stage , embryonic stage && larval stage , embryonic stage&&larval stage " " yolk

, larval brain

, imaginal disc

, oocyte

, ventral furrow | vicinity of

, amnioproctodeal invagination | vicinity of

, nurse cell

, ring gland

, cephalic furrow | vicinity of

, larval optic lobe

, lymph gland

, embryonic/larval tracheal system

, embryonic/larval salivary gland

, embryonic/larval fat body

" viable DRSC03349 E -0.39789249 0.113950392 -1.664635496 0.59493807 -0.16923865 -0.150656505 FBgn0003888 betaTub60D beta-Tubulin at 60D http://flybase.org/reports/FBgn0003888 - protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR002453, InterPro:IPR008280, InterPro:IPR017975 GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR003008, InterPro:IPR008280 structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity structural constituent of cytoskeleton ; GO:0005200 | inferred from direct assay" "microtubule-based process ; GO:0007017 | inferred from electronic annotation with InterPro:IPR000217, InterPro:IPR002453, InterPro:IPR017975 response to light stimulus ; GO:0009416 | inferred from mutant phenotype heart development ; GO:0007507 | non-traceable author statement neurogenesis ; GO:0022008 | inferred from mutant phenotype microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity larval behavior ; GO:0030537 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype axonogenesis ; GO:0007409 | inferred from mutant phenotype" microtubule ; GO:0005874 | inferred from direct assay microtubule ; GO:0005874 | inferred from sequence or structural similarity "Tub60D, CG3401, betaTub60D, 143391_i_at, beta-tub, beta3 TU, beta-Tub6D, p50/tubulin, p53/tubulin, p50, p53, beta3, BETA 60D, D.m.BETA-60D, B3t, beta3-Tub, beta[[3]]-Tub, Dmbeta3, betaTub60C, T, beta3t, beta[[3]] tubulin, 3t, DTB3, beta[[3]]-tubulin, beta60C, betaTub3, beta-Tub60D, Tub, beta3Tub, betaTub, betatub60D, beta3-tubulin, beta3TUB, beta3tub, Tub2E, tubulin" "IPR000217:Tubulin, IPR002453:Beta tubulin, IPR003008:Tubulin/FtsZ, GTPase domain, IPR008280:Tubulin/FtsZ, C-terminal, IPR017975:Tubulin, conserved site, IPR018316:Tubulin/FtsZ, 2-layer sandwich domain, IPR013838:Beta tubulin, autoregulation binding site" CG3401 27-Aug-18 DroID_v2018_08 "Drer\tubb6, Drer\tubb2b, Drer\zgc:153426, Drer\zgc:153264, Drer\zgc:65894, Drer\tubb2, Drer\tubb1, Drer\tubb5, Drer\zgc:55461, Drer\tubb4b" Scer\TUB2 "Cele\tbb-2, Cele\tbb-1, Cele\ben-1, Cele\tbb-4, Cele\mec-7" "Xtro\tubb4b, Xtro\tube1, Xtro\tubb2b, Xtro\tubb6, Xtro\tubb4a, Xtro\tubb3, Xtro\tubb" "Mmus\Tubb4a, Mmus\Tubb1, Mmus\Tubb3, Mmus\Tubb2a, Mmus\Tubb5, Mmus\Tubb2b, Mmus\Tubb4b, Mmus\Tubb6, Mmus\Tube1" "Hsap\TUBB6, Hsap\TUBB3, Hsap\TUBB8, Hsap\TUBB4B, Hsap\TUBB4A, Hsap\TUBB1, Hsap\TUBB2B, Hsap\TUBE1, Hsap\TUBB, Hsap\TUBB2A" " embryonic stage | stage 13 , embryonic stage | 0-10 hr , prepupal stage , larval stage | third instar , pupal stage | mid , oogenesis stage && adult stage | female , embryonic stage | stage 12 , embryonic stage | 9-15 hr , pupal stage , oogenesis stage && pupal stage , embryonic stage | stage 14 , embryonic stage | >=stage 11 , embryonic stage | stage 10 , adult stage | male , pupal stage | mid-late " " visceral mesoderm

, ventral metathoracic disc

, indirect flight muscle

, follicle cell

, mesoderm

, ovary

, head mesoderm

, dorsal metathoracic disc

, dorsal mesothoracic disc

, optic lobe | presumptive

, somatic mesoderm

, adult brain | presumptive

, testis | cyst cell

, muscle system

, eye-antennal disc

, testis

, ventral mesothoracic disc

, ventral prothoracic disc

" embryonic stage | stage 17 mesoderm | posterior | segmentally repeated pattern

"viable,sterile,lethal - all die before end of P-stage,some die during pharate adult stage,lethal,recessive,partially lethal - majority die,male fertile,fertile,flightless,phototaxis defective,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority live,visible,male sterile,neuroanatomy defective,some die during pupal stage,locomotor behavior defective" "axoneme,meiotic cell cycle | male,embryonic/larval midgut,chordotonal organ & microtubulePx2),optic lobe,eye,lamina,medulla & axon,photoreceptor cell R8 & axon,photoreceptor cell R7 & axon,rhabdomere,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,tormogen cell,mesothoracic tergum" FBgn0001297 kay kayak http://flybase.org/reports/FBgn0001297 "FBgn0053956, FBgn0000468, FBgn0000725, FBgn0003506, FBgn0039693, FBtr0085478, FBpp0084844, FBtr0085479, FBpp0084845, FBtr0085480, FBpp0084846" protein_coding_gene "transcription factor binding ; GO:0008134 | traceable author statement DNA binding ; GO:0003677 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with HDAC1 inferred from physical interaction with chm repressing transcription factor binding ; GO:0070491 | inferred from physical interaction with vri transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from sequence or structural similarity RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with Jra protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P18289 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with Cka" "positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay JNK cascade ; GO:0007254 | non-traceable author statement adult chitin-containing cuticle pigmentation ; GO:0048085 | inferred from mutant phenotype establishment of planar polarity ; GO:0001736 | non-traceable author statement synaptic growth at neuromuscular junction ; GO:0051124 | inferred from genetic interaction with Jra wing disc development ; GO:0035220 | inferred from mutant phenotype second mitotic wave involved in compound eye morphogenesis ; GO:0016330 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype wound healing ; GO:0042060 | inferred from mutant phenotype R3/R4 cell fate commitment ; GO:0007464 | traceable author statement ovarian follicle cell migration ; GO:0007297 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype embryo development ; GO:0009790 | inferred from mutant phenotype dorsal closure ; GO:0007391 | traceable author statement response to wounding ; GO:0009611 | inferred from mutant phenotype R3/R4 cell fate commitment ; GO:0007464 | inferred from mutant phenotype antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype imaginal disc fusion, thorax closure ; GO:0046529 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype germ cell development ; GO:0007281 | inferred from mutant phenotype imaginal disc fusion, thorax closure ; GO:0046529 | traceable author statement border follicle cell migration ; GO:0007298 | inferred from genetic interaction with Pvr dorsal closure ; GO:0007391 | non-traceable author statement collateral sprouting of injured axon ; GO:0048674 | inferred from mutant phenotype regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle ; GO:0031660 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay transcription factor complex ; GO:0005667 | inferred from physical interaction with Jra "CG15509, CG15507, DFos, AP-1, Dfos, DFOS, D-fos, D-Fos, fos, Fos, AP1, d-fos, c-Fos, dFRA, dFos, Fra, DFra, dFra, dAP-1, kay, D-fos/kay, CG33956, Kay, dfos, c-fos, fbz, dlhD, fra, KAY, FOS, DM30, DM3" "IPR000837:AP-1 transcription factor, IPR004827:Basic-leucine zipper domain" CG33956 27-Aug-18 DroID_v2018_08 "Drer\atf1, Drer\fosab, Drer\batf, Drer\batf3, Drer\si:ch211-153j24.3, Drer\fosl1a, Drer\si:ch211-59d15.4, Drer\fosaa, Drer\atf7a, Drer\jdp2a, Drer\fosl1b, Drer\atf2, Drer\creb1a, Drer\fosl2, Drer\atf3, Drer\atf7b, Drer\creb5b, Drer\jdp2b, Drer\fosb, Drer\crema" "Scer\ACA1, Scer\CST6, Scer\SKO1" "Cele\fos-1, Cele\zip-11, Cele\crh-1" "Xtro\atf7, Xtro\atf3, Xtro\fosl2, Xtro\atf1, Xtro\batf, Xtro\creb5, Xtro\fos, Xtro\fosl1, Xtro\atf2, Xtro\fosb" "Mmus\Fos, Mmus\Atf1, Mmus\Atf7, Mmus\Atf3, Mmus\Batf3, Mmus\Fosl1, Mmus\Batf, Mmus\Creb5, Mmus\Atf2, Mmus\Batf2, Mmus\Jdp2, Mmus\Fosl2, Mmus\Fosb, Mmus\Creb1" "Hsap\ATF1, Hsap\FOS, Hsap\CREM, Hsap\BATF, Hsap\ATF2, Hsap\FOSL1, Hsap\JDP2, Hsap\CREB1, Hsap\ATF7, Hsap\FOSL2, Hsap\CREB5, Hsap\ATF3, Hsap\FOSB, Hsap\BATF3, Hsap\BATF2" " embryonic stage | stage 15 , embryonic stage , embryonic stage | 4-8 hr " " eo neuron

, dorsal ectoderm

, embryonic/larval midgut

, muscle attachment site

, amnioserosa

, embryonic/larval hindgut

, anal pad

, multidendritic neuron

, embryonic peripheral nervous system | restricted

, head | restricted

" "neuroanatomy defective,locomotor rhythm defective,viable,fertile,planar polarity defective,somatic clone,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,visible,wild-type,lethal,wound healing defective,cell lethalcell lethal,heat sensitive,neurophysiology defective,conditional,partially,partially lethal - majority live,lethal - all die before end of pupal stage,some die during pupal stage,mitotic cell cycle defective,increased cell death,developmental rate defective,long lived,male limited,starvation stress response defective,temperature response defective,gravitaxis defective" "Kenyon cell,axoney-OK107,dorsal multidendritic neuron ddaD,dorsal multidendritic neuron ddaE,dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa,ventral multidendritic neuron vdaB,ommatidium,photoreceptor cell R4,somatic clone,embryonic/larval hemocyte | third instar larval stage,dendrite,RP2 motor neuron,eye photoreceptor cell,egg,maternal effect,dorsal appendage,nurse cell & nucleus | somatic clone,stage S14 oocyte,adult thorax,dorsal,mesothoracic cleft,embryonic dorsal epidermis,dorsal closure embryo,embryonic epidermis,embryonic head,embryo,wing disc,wing,embryonic ventral epidermis,follicle cell,stage S9 oocyte,embryonic/first instar larval cuticle,wing vein L3,wing vein L5,wing vein,heart primordium,scutellum,imaginal disc,pupal thorax,salivary gland,eye,cuprophilic cell,midgut interstitial cell,adult midgut precursor cell,bouton,neuromuscular junction | larval stage,terminal bouton,synapse,anterior crossvein,wing vein L2,wing vein L4,neuromuscular junctionBG380,segmental nerve,conditional,dendrite | somatic cloneFLP1UAS.cUa, Act.PU, eve.RRK,motor neuron,thorax,pigment cell,trichogen cell,mesothoracic tergum,adult heart,RU486 conditional,posterior" DRSC16977 IE 3.022447147 4.211683207 2.840500332 1.748045363 -0.463202103 -0.167621605 FBgn0038167 Lkb1 Lkb1 kinase http://flybase.org/reports/FBgn0038167 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000680267 protein kinase activator activity ; GO:0030295 | inferred from biological aspect of ancestor with PANTHER:PTN001552748 protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with HGNC:11389 protein kinase activity ; GO:0004672 | non-traceable author statement" "peptidyl-threonine phosphorylation ; GO:0018107 | inferred from biological aspect of ancestor with PANTHER:PTN000680267 protein phosphorylation ; GO:0006468 | non-traceable author statement protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with HGNC:11389 positive regulation of protein serine/threonine kinase activity ; GO:0071902 | inferred from biological aspect of ancestor with PANTHER:PTN001552748 border follicle cell delamination ; GO:0030709 | inferred from mutant phenotype mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype peptidyl-serine phosphorylation ; GO:0018105 | inferred from biological aspect of ancestor with PANTHER:PTN000680267 pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype asymmetric neuroblast division ; GO:0055059 | inferred from mutant phenotype protein localization to cell cortex ; GO:0072697 | inferred from mutant phenotype inferred from genetic interaction with mira, fray maintenance of neuroblast polarity ; GO:0045201 | inferred from direct assay determination of adult lifespan ; GO:0008340 | inferred from direct assay establishment or maintenance of cell polarity ; GO:0007163 | non-traceable author statement regulation of JNK cascade ; GO:0046328 | inferred from direct assay oocyte microtubule cytoskeleton organization ; GO:0016325 | inferred from mutant phenotype positive regulation of apoptotic process ; GO:0043065 | inferred from direct assay" nucleus ; GO:0005634 | inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "lkb1, LKB1, Lkb1, dLKB1, DmLKB1, PAR-4, CG9374, LKB1/PEUTZ JEGHERS KINASE, STK11, par-4, anon-EST:Posey135, PAR4, dlkb1" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR020636:Calcium/calmodulin-dependent/calcium-dependent protein kinase" CG9374 27-Aug-18 DroID_v2018_08 Drer\stk11 "Scer\SAK1, Scer\TOS3" Cele\par-4 Xtro\stk11 Mmus\Stk11 Hsap\STK11 "hyperplasia,long lived,female limited,heat sensitive,cell polarity defective,mitotic cell cycle defective,decreased cell death,lethal - all die before end of pupal stage,some die during pupal stage,increased cell death,lethal,recessive,germline clone,maternal effect,cell cycle defective,cytokinesis defective" "wing,eye,embryonic/larval brain,ventral nerve cord,wing disc,wing blade,follicle cell,oocyte,germline clone,oocyte & microtubule | germ-line clone,border follicle cell,somatic clone,neuroblast,spindle,centrosome,brain,aster,kinetochore microtubule,spindle microtubule,spindleurd),asterurd),kinetochore microtubuleurd),spindle microtubuleurd),spindle & larval neuroblasturd),embryonic/larval neuroblast,centrosome & larval neuroblasturd),scutellum,adult thoracic sensillum" FBgn0015858 anon-14Ab anon-14Ab http://flybase.org/reports/FBgn0015858 - gene - - - "td28, anon-14Ab" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0026181 Rok Rho kinase http://flybase.org/reports/FBgn0026181 FBgn0028698 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR000961, InterPro:IPR002290, InterPro:IPR017441 Rho GTPase binding ; GO:0017048 | inferred from electronic annotation with InterPro:IPR015008 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement GTPase binding ; GO:0051020 | inferred from physical interaction with Rho1 protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Rho1 protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity inferred from direct assay" regulation of phosphorylation ; GO:0042325 | inferred from direct assay epidermis development ; GO:0008544 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement dorsal closure ; GO:0007391 | traceable author statement regulation of axonogenesis ; GO:0050770 | inferred from genetic interaction with LIMK1 actin cytoskeleton reorganization ; GO:0031532 | inferred from mutant phenotype morphogenesis of embryonic epithelium ; GO:0016331 | inferred from mutant phenotype regulation of planar cell polarity pathway involved in axis elongation ; GO:2000040 | inferred from direct assay establishment of ommatidial planar polarity ; GO:0042067 | inferred from mutant phenotype Rho protein signal transduction ; GO:0007266 | inferred from physical interaction with Rho1 regulation of cell shape ; GO:0008360 | inferred from mutant phenotype establishment of planar polarity ; GO:0001736 | traceable author statement imaginal disc-derived wing hair organization ; GO:0035317 | inferred from mutant phenotype inferred from genetic interaction with dsh inferred from genetic interaction with fz actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype nuclear axial expansion ; GO:0035191 | inferred from mutant phenotype regulation of actin cytoskeleton organization ; GO:0032956 | inferred from mutant phenotype cortical protein anchoring ; GO:0032065 | inferred from mutant phenotype positive regulation of stress fiber assembly ; GO:0051496 | inferred from genetic interaction with Fhos female germline ring canal stabilization ; GO:0008335 | inferred from mutant phenotype regulation of protein phosphorylation ; GO:0001932 | inferred from mutant phenotype mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype oocyte development ; GO:0048599 | inferred from mutant phenotype apical constriction involved in gastrulation ; GO:0003384 | inferred from mutant phenotype oocyte axis specification ; GO:0007309 | inferred from mutant phenotype establishment of imaginal disc-derived wing hair orientation ; GO:0001737 | inferred from mutant phenotype nurse cell nucleus anchoring ; GO:0007302 | inferred from mutant phenotype regulation of actin filament bundle assembly ; GO:0032231 | inferred from mutant phenotype inferred from genetic interaction with dsh inferred from genetic interaction with fz mitotic cytokinesis ; GO:0000281 | inferred from direct assay positive regulation of wound healing ; GO:0090303 | inferred from mutant phenotype negative regulation of response to wounding ; GO:1903035 | inferred from mutant phenotype regulation of cell junction assembly ; GO:1901888 | inferred from genetic interaction with Pten establishment of protein localization ; GO:0045184 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype mitotic spindle elongation ; GO:0000022 | inferred from mutant phenotype regulation of myoblast fusion ; GO:1901739 | inferred from genetic interaction with Rho1 ovarian nurse cell to oocyte transport ; GO:0007300 | inferred from mutant phenotype ommatidial rotation ; GO:0016318 | non-traceable author statement apical cortex ; GO:0045179 | colocalizes_with inferred from direct assay cell-cell contact zone ; GO:0044291 | inferred from direct assay "ROCK, Drok, Rok, DROK, ROK, ROKalpha/beta, drok, Rock, RhoK, dROK, dRok, DRhk, ROCK1, CG9774, Rhk, ROCK-1, rok, DRok, Rok/ROCK, ROCK2" "IPR029875:Rho-associated protein kinase LET-502, IPR000719:Protein kinase domain, IPR000961:AGC-kinase, C-terminal, IPR001849:Pleckstrin homology domain, IPR002219:Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR015008:Rho binding domain, IPR017441:Protein kinase, ATP binding site, IPR011993:PH domain-like, IPR020684:Rho-associated protein kinase 1/2" CG9774 27-Aug-18 DroID_v2018_08 "Drer\LOC101882847, Drer\rock1, Drer\rock2b, Drer\rock2a, Drer\cdc42bpb" "Scer\HSL1, Scer\CBK1" Cele\let-502 "Xtro\rock2, Xtro\rock1, Xtro\tacc3" "Mmus\Rock2, Mmus\Tacc3, Mmus\Rock1, Mmus\Cdc42bpb, Mmus\Tacc2" "Hsap\ROCK2, Hsap\CDC42BPB, Hsap\TACC3, Hsap\ROCK1" " embryonic stage , larval stage | third instar " "

ubiquitous , imaginal disc | ubiquitous

" "lethal - all die before end of pupal stage,visible,planar polarity defective,partially lethal - majority die,some die during pupal stage,wound healing defective,mitotic cell cycle defective,neuroanatomy defective,cell polarity defective,somatic clone,cell shape defective,increased cell death,wild-type,lethal,viable,recessive,female sterile,germline clone,axis specification defective,male limited,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage" "presumptive embryonic salivary gland,egg chamber,conditional,wing,mesothoracic tergum,S2 cell-line & spindle,S2 cell-line & cell,S2 cell-line & spindle microtubule,S2 cell-line & polar microtubule,embryonic/larval epidermis,oocyte,somatic clone,vertical lobe of adult mushroom body,nucleus,epithelial cell,eye,photoreceptor cell,crossvein,wing margin,macrophage | third instar larval stage,stress fiber | third instar larval stageHml.ëÓ,contractile ring | somatic clone,eye photoreceptor cell,supernumerary,ommatidium,wing hair,cell autonomous,mushroom body & axon | somatic clone,egg,germline clone,dorsal appendage,yolk granule | germline clone,nurse cell,nurse cell ring canal,filamentous actin & oocyte | germ-line clone,filamentous actin & nurse cell | germ-line clone,plasma membrane & oocyte | germ-line clone,hub cell,adherens junction | somatic clone,morphogenetic furrow,epithelium,follicle cell,anterior embryonic/larval midgut,male limited,embryonic proventriculus,embryonic/first instar larval cuticle,dorsal,dorsal hair,embryonic leading edge cell,wing disc | third instar larval stage,wing disc,somatic clone | third instar larval stage" DRSC20277 K 1.140488567 -0.484681497 -0.401458467 0.182061105 -0.607747052 -1.512870256 FBgn0000547 ed echinoid http://flybase.org/reports/FBgn0000547 "FBgn0022256, FBgn0031582, FBgn0031583, FBgn0031584" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Grip "negative regulation of neurogenesis ; GO:0050768 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype negative regulation of hippo signaling ; GO:0035331 | inferred from genetic interaction with yki inferred from genetic interaction with sav ommatidial rotation ; GO:0016318 | inferred from mutant phenotype inferred from genetic interaction with fz inferred from genetic interaction with pnt inferred from genetic interaction with stan inferred from genetic interaction with cno muscle organ morphogenesis ; GO:0048644 | inferred from mutant phenotype negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | non-traceable author statement imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype negative regulation of organ growth ; GO:0046621 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype regulation of hippo signaling ; GO:0035330 | inferred from physical interaction with ex inferred from physical interaction with sav inferred from physical interaction with Mer inferred from physical interaction with kibra homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from direct assay inferred from mutant phenotype morphogenesis of an epithelium ; GO:0002009 | inferred from mutant phenotype cuticle development ; GO:0042335 | inferred from genetic interaction with UniProtKB:Q0KHR3,UniProtKB:Q9VX75,UniProtKB:X2JCB3,UniProtKB:X2JFU8 lateral inhibition ; GO:0046331 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype regulation of actin cytoskeleton organization by cell-cell adhesion ; GO:0090138 | inferred from mutant phenotype single organismal cell-cell adhesion ; GO:0016337 | inferred from mutant phenotype negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from mutant phenotype inferred from genetic interaction with Ras85D inferred from genetic interaction with rl inferred from genetic interaction with Egfr inferred from genetic interaction with RasGAP1 inferred from genetic interaction with aos inferred from genetic interaction with rho inferred from genetic interaction with sty branch fusion, open tracheal system ; GO:0035147 | inferred from mutant phenotype regulation of actin cytoskeleton organization ; GO:0032956 | inferred from mutant phenotype sensory organ development ; GO:0007423 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype negative regulation of fusion cell fate specification ; GO:0035157 | inferred from mutant phenotype contractile actin filament bundle assembly ; GO:0030038 | inferred from mutant phenotype wound healing ; GO:0042060 | inferred from mutant phenotype dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype epidermal growth factor receptor signaling pathway ; GO:0007173 | inferred from mutant phenotype inferred from physical interaction with Nrg" cell-cell adherens junction ; GO:0005913 | inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay adherens junction ; GO:0005912 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model "ed, CG16842, E(Elp)[24D], CT13476, CT35484, l(2)k01102, 1X5, E(Elp)24D, CG15424, CG12676, Ed" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR003961:Fibronectin type III, IPR007110:Immunoglobulin-like domain, IPR013162:CD80-like, immunoglobulin C2-set, IPR013783:Immunoglobulin-like fold" CG12676 27-Aug-18 DroID_v2018_08 "Drer\kirrel3b, Drer\kirrela, Drer\kirrel3l, Drer\kirrel3a, Drer\tmigd1, Drer\kirrelb" - "Cele\igcm-1, Cele\F22D3.6" - "Mmus\Kirrel2, Mmus\Malt1, Mmus\Kirrel3, Mmus\Kirrel" "Hsap\KIRREL2, Hsap\KIRREL, Hsap\MALT1, Hsap\KIRREL3" "lethal,recessive,behavior defective,cell shape defective,cell autonomous,somatic clone,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,heat sensitive,partially lethal - majority die,some die during pupal stage,lethal - all die before end of pupal stage,visible,dominant,lethal - all die before end of larval stage,some die during larval stage,wild-type,viable,size defective,cell non-autonomous,wound healing defective,germline clone,cell adhesion defective" "embryonic/larval tracheal system,germline clone,rescuable maternal effect,embryo,embryonic epidermis,embryonic/larval dorsal trunk,embryonic/larval lateral trunk,tracheal fusion cell,ectopic,wing disc,cell autonomous,somatic clone,cell non-autonomous,presumptive embryonic/larval central nervous system,embryonic neuroblast,embryonic/larval neuron,supernumerary,ventral nerve cord,macrochaeta,microchaeta,eye,wing vein L2,wing margin,distal,dorsocentral bristle,scutellar bristle,chemosensory ventral triple row & microchaeta | ectopic,dorsal triple row & microchaeta | ectopic,photoreceptor cell R8,sex comb,photoreceptor cell R7,wing,ommatidium,ommatidial precursor cluster,actomyosin | dorsal closure stagec381,epidermal cell | dorsal closure stage,eye photoreceptor cell,dorsal triple row & macrochaeta | ectopic,adult thorax & microchaeta | ectopic,embryonic/first instar larval cuticle,denticle belt,chorion | somatic clone,follicle cell,dorsal closure embryo,actin filament bundle | ectopic | somatic clone,adherens junction | somatic clone,embryonic leading edge cell & actomyosin,embryonic dorsal epidermis,embryonic segment,sensory mother cell,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,mystery cell,cone cell,wing vein,ventral longitudinal muscle,lateral transverse muscle,photoreceptor cell,apical plasma membrane & cell & dorsal mesothoracic disc & third instar larva | somatic clone,wing hair,wing cell,sensillum campaniformium & wing | supernumerary | somatic clone,oocyte,scutellum,dorsal appendage,actomyosin | dorsal closure stage,embryonic/larval dorsal anastomosis,posterior,chaeta,trichogen cell,mesothoracic tergum" DRSC00439 E -1.109723912 0.005681429 0.031203273 2.062307314 0.549157922 0.554889436 FBgn0030600 hiw highwire http://flybase.org/reports/FBgn0030600 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:O62609 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9V6L9 protein binding ; GO:0005515 | inferred from physical interaction with Rae1 inferred from physical interaction with Fsn zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with UniProtKB:Q8WY64 regulation of synaptic growth at neuromuscular junction ; GO:0008582 | traceable author statement negative regulation of BMP signaling pathway ; GO:0030514 | inferred from genetic interaction with UniProtKB:O62609 inferred from genetic interaction with UniProtKB:Q9VZI9 response to axon injury ; GO:0048678 | inferred from mutant phenotype regulation of synaptic growth at neuromuscular junction ; GO:0008582 | inferred from mutant phenotype adult walking behavior ; GO:0007628 | non-traceable author statement protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with UniProtKB:Q8WY64 synapse organization ; GO:0050808 | inferred from direct assay regulation of terminal button organization ; GO:2000331 | inferred from mutant phenotype long-term memory ; GO:0007616 | inferred from mutant phenotype detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype locomotion ; GO:0040011 | non-traceable author statement BMP signaling pathway ; GO:0030509 | inferred from physical interaction with UniProtKB:O62609 negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype autophagy ; GO:0006914 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay cytoplasmic vesicle ; GO:0031410 | inferred from direct assay "CG9049, CG9041, CG32592, hiw, Hiw" "IPR000408:Regulator of chromosome condensation, RCC1, IPR001841:Zinc finger, RING-type, IPR012983:PHR, IPR008979:Galactose-binding domain-like, IPR009091:Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II, IPR014756:Immunoglobulin E-set, IPR004939:APC10/DOC domain, IPR017868:Filamin/ABP280 repeat-like, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013783:Immunoglobulin-like fold" CG32592 27-Aug-18 DroID_v2018_08 Drer\mycbp2 - "Cele\F07B7.12, Cele\rpm-1" Xtro\mycbp2 Mmus\Mycbp2 Hsap\MYCBP2 "neuroanatomy defective,conditional,neurophysiology defective,somatic clone,decreased cell growth,recessive,locomotor behavior defective,viable" "embryonic/larval neuromuscular junction,NMJ bouton,supernumerary,synapse,neuromuscular junction | larval stage,dorsal multidendritic neuron ddaC,neuromuscular junction,indirect flight muscle motor neuron MN4,terminal bouton,segmental nerve,conditional,bouton,wing vein L1,somatic clone,terminal boutonelav.Switch.PO,neuromuscular junctionelav.Switch.PO,synapseelav.Switch.PO,indirect flight muscle motor neuron MN4 & bouton | ectopic,neuroblast,synaptic vesicle,motor neuron,giant fiber neuron,tergotrochanteral muscle motor neuron,synapseelav.Switch.PO, hiwëÓRCC1.UAS.TZzzzTAP,synapseelav.Switch.PO, hiwëÓPHR.UAS.TZzzzTAP,synapseelav.Switch.PO, hiwHindIII.UAS.TZzzzHis6,THsapMYC,synapseelav.Switch.PO, hiwëÓN.UAS.TZzzzTAP,synapseelav.Switch.PO, hiwND8,eye" FBgn0003371 sgg shaggy http://flybase.org/reports/FBgn0003371 "FBgn0026697, FBgn0026849, FBgn0027246, FBgn0028324, FBgn0029071, FBgn0066814" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein kinase activity ; GO:0004672 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:O16844 protein binding ; GO:0005515 | inferred from physical interaction with Axn protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity kinase activity ; GO:0016301 | inferred from direct assay" chitin-based larval cuticle pattern formation ; GO:0035293 | inferred from mutant phenotype circadian rhythm ; GO:0007623 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype negative regulation of smoothened signaling pathway ; GO:0045879 | inferred from mutant phenotype circadian rhythm ; GO:0007623 | traceable author statement wing and notum subfield formation ; GO:0035309 | inferred from mutant phenotype entrainment of circadian clock ; GO:0009649 | inferred from mutant phenotype positive regulation of protein catabolic process ; GO:0045732 | inferred from mutant phenotype establishment of epithelial cell planar polarity ; GO:0090163 | inferred from mutant phenotype inferred from genetic interaction with aPKC pseudocleavage involved in syncytial blastoderm formation ; GO:0030589 | non-traceable author statement response to anesthetic ; GO:0072347 | inferred from mutant phenotype negative regulation of JUN kinase activity ; GO:0043508 | inferred from mutant phenotype Notch signaling pathway ; GO:0007219 | traceable author statement rhythmic behavior ; GO:0007622 | traceable author statement regulation of proteolysis ; GO:0030162 | inferred from direct assay protein phosphorylation ; GO:0006468 | non-traceable author statement heart development ; GO:0007507 | non-traceable author statement Wnt signaling pathway ; GO:0016055 | traceable author statement protein phosphorylation ; GO:0006468 | inferred from direct assay circadian rhythm ; GO:0007623 | non-traceable author statement olfactory learning ; GO:0008355 | inferred from mutant phenotype female meiotic division ; GO:0007143 | inferred from mutant phenotype negative regulation of Wnt signaling pathway ; GO:0030178 | traceable author statement ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype somatic stem cell population maintenance ; GO:0035019 | inferred from mutant phenotype habituation ; GO:0046959 | inferred from mutant phenotype regulation of calcineurin-NFAT signaling cascade ; GO:0070884 | inferred from mutant phenotype epithelial cell morphogenesis ; GO:0003382 | inferred from mutant phenotype inferred from genetic interaction with aPKC regulation of microtubule cytoskeleton organization ; GO:0070507 | inferred from mutant phenotype positive regulation of proteasomal ubiquitin-dependent protein catabolic process ; GO:0032436 | inferred from direct assay negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype heart development ; GO:0007507 | traceable author statement regulation of hemocyte differentiation ; GO:0045610 | inferred from mutant phenotype chaeta morphogenesis ; GO:0008407 | non-traceable author statement regulation of protein import into nucleus ; GO:0042306 | traceable author statement negative regulation of smoothened signaling pathway ; GO:0045879 | inferred from direct assay positive regulation of mitotic metaphase/anaphase transition ; GO:0045842 | inferred from mutant phenotype regulation of circadian rhythm ; GO:0042752 | inferred from mutant phenotype spindle organization ; GO:0007051 | inferred from mutant phenotype sensory organ development ; GO:0007423 | inferred from mutant phenotype segment polarity determination ; GO:0007367 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | non-traceable author statement synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype nucleoplasm ; GO:0005654 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay axon ; GO:0030424 | inferred from direct assay mitotic spindle ; GO:0072686 | inferred from direct assay neuromuscular junction ; GO:0031594 | inferred from direct assay female germline ring canal ; GO:0035324 | inferred from direct assay fusome ; GO:0045169 | inferred from direct assay "GSK3, sgg, GSK3beta/SGG, Zw3, GSK, zw3, GSK3beta, Gsk3, GSK-3, GSKbeta, GSK-3beta, ZW3, CG2621, EG:155E2.3, Zw3-sh, DMSGG3, Sgg, SGG/GSK3b, Zw3/GSK3, sgg46, sgg39, sgg10, DMZ3K25Z, sgg-zw3, l(1)3Ba, zw-3, Zw-3, zw3[sgg], Zw3[sgg], zw3/sgg, sgg/zw3, zw[3], zw3(sgg), l(1)zw3, ZW-3, l(1)G0055, l(1)G0183, l(1)G0263, l(1)G0335, EG:BACR7C10.8, anon-WO03040301.254, gsk3, Dmsgg3, SGG, Sgg/Zw3/GSK3, Gsk-3, GSK-3B, GSK3betagr;, zw3/GSK3beta, Dm Zw3, GSK-3betaSgg, GSK3Beta, GSK3-beta, Gsk-3beta, GSK3A" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR033573:Glycogen synthase kinase-3 beta" CG2621 27-Aug-18 DroID_v2018_08 "Drer\gsk3aa, Drer\si:dkeyp-80c12.7, Drer\gsk3b, Drer\gsk3ab" "Scer\YGK3, Scer\MCK1, Scer\RIM11, Scer\MRK1" "Cele\C44H4.6, Cele\ire-1, Cele\gck-1, Cele\R03D7.5, Cele\gsk-3" "Xtro\gsk3a, Xtro\gsk3b" "Mmus\Gsk3b, Mmus\Gsk3a" "Hsap\GSK3B, Hsap\GSK3A, Hsap\MYLK" larval stage | third instar nerve terminal | subset

"lethal,recessive,visible,somatic clone,viable,locomotor rhythm defective,circadian rhythm defective,behavior defective,neuroanatomy defective,neurophysiology defective,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of pupal stage,some die during pupal stage,wild-type,maternal effect,germline clone,developmental rate defective,mitotic cell cycle defective,planar polarity defective,cell non-autonomous,cell polarity defective,lethal - all die before end of embryonic stage,some die during embryonic stage,rescuable maternal effect,lethal - all die before end of larval stage,some die during larval stage,non-rescuable maternal effect,some die during third instar larval stage,meiotic cell cycle defective,short lived,smell perception defective,heat sensitive,fertile,chemical sensitive" "eye,somatic clone,eye disc,macrochaeta,supernumerary,synapse,macrochaeta & wing,embryonic/larval dorsal vessel,ommatidium,embryonic/first instar larval cuticle,germline clone,maternal effect,denticle belt,embryonic head,embryonic/larval spiracle,filzkorper,presumptive embryonic/larval peripheral nervous system,presumptive embryonic/larval central nervous system,embryonic/larval brain,wing,leg,tibia,tarsal segment,ventral thoracic disc,ventral thoracic disc & macrochaeta | somatic clone,syncytial blastoderm embryo,nucleus | embryonic stage 4 | germline clone,follicle stem cell,germline cyst,follicle cell,embryonic epidermis,dorsal,dorsal hair,embryonic Malpighian tubule,mesothoracic tarsal bristle longitudinal row 2,mesothoracic tarsal bristle longitudinal row 3,mesothoracic tarsal bristle longitudinal row 4,mesothoracic tarsal bristle longitudinal row 5,mesothoracic tarsal bristle longitudinal row 6,mesothoracic tarsal bristle longitudinal row 7,abdominal 1 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,denticle,rescuable maternal effect,embryonic/larval somatic muscle,stomodeal invagination,midgut constriction 1,ectopic,posterior compartment,precursor,cell non-autonomous,wing margin bristle,wing vein,sensillum campaniformium,wing blade,mechanosensory ventral triple row bristle,wing sensillum,imaginal disc,egg,female reproductive system,wing hair,non-rescuable maternal effect,embryonic/larval neuromuscular junction,bouton,external sensory organ precursor cell,microchaeta,adult cuticle & abdomen | somatic clone,anterior,adult thorax & macrochaeta | somatic clone,adult thorax & microchaeta | somatic clone,cuticle,macrochaeta & wing | ectopic | somatic clone,1st axillary sclerite,2nd axillary sclerite,3rd axillary sclerite,unnamed wing hinge sclerite,axillary pouch,macrochaeta & mesothoracic tergum | somatic clone | cell autonomous,macrochaeta & scutum | somatic clone | cell autonomous,cell autonomous,macrochaeta & prescutum | somatic clone | cell autonomous,sensory mother cell,NMJ bouton,dendritic arborizing neuron | third instar larval stage,wing margin,mesothoracic tergum,morphogenetic furrow,melanotic mass,lamellocyte,crystal cell,scutellum,adult thorax & chaeta-537.4,dorsocentral bristle,posterior dorsocentral bristle,bouton | larval stage,scutellar bristle,wing disc,adult thorax & microchaeta-537.4,synapse796,antennal lobe,synapseGH298,intrinsic neuron,antennal lobe glomerulus DM2,synapseNP1227,synapsekra-krasavietz,synapseSxl-NP2426,synapseSxl-NP2426, kra-krasavietz,synapseTab2-201Y,adult mushroom body,eye | pharate adult stage,head | pharate adult stage,synapseD42,adult thorax,dorsal denticle,cuprophilic cell,midgut constriction 2,interommatidial bristle" FBgn0004101 bs blistered http://flybase.org/reports/FBgn0004101 "FBgn0000156, FBgn0000223, FBgn0010354, FBgn0010535" protein_coding_gene "protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR002100 core promoter proximal region sequence-specific DNA binding ; GO:0000987 | inferred from electronic annotation with InterPro:IPR033897 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | contributes_to inferred from physical interaction with Mrtf activating transcription factor binding ; GO:0033613 | inferred from physical interaction with Mrtf" "terminal branching, open tracheal system ; GO:0007430 | traceable author statement terminal cell fate specification, open tracheal system ; GO:0035154 | traceable author statement short-term memory ; GO:0007614 | inferred from mutant phenotype cell fate commitment ; GO:0045165 | traceable author statement pupal development ; GO:0035209 | inferred from mutant phenotype imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype instar larval development ; GO:0002168 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | traceable author statement cell differentiation ; GO:0030154 | inferred from mutant phenotype apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from expression pattern imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | non-traceable author statement wing disc development ; GO:0035220 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | non-traceable author statement open tracheal system development ; GO:0007424 | traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay" nucleus ; GO:0005634 | inferred from direct assay "bs/DSRF, DSRF, SRF, D-SRF, dSRF, BS, DmSRF, Group IIc, DSrf/bs, pruned/DSRF, dsrf, Srf, DSrf, px, ba, l(2)03267, Serf, CG3411, bs, bs/Dsrf, Bs, Mal, srf" "IPR002100:Transcription factor, MADS-box, IPR033897:MADS SRF-like" CG3411 27-Aug-18 DroID_v2018_08 "Drer\srfb, Drer\srfa" "Scer\MCM1, Scer\ARG80" "Cele\mef-2, Cele\unc-120" Xtro\srf Mmus\Srf Hsap\SRF " embryonic stage | >=stage 14 , embryonic stage | stage 16 , embryonic stage | stage >=14 " " abdominal segment 1--8

, embryonic/larval somatic muscle

, metathoracic segment | restricted

, embryonic central nervous system | restricted

, mesothoracic segment | restricted

, embryonic/larval midgut

, embryonic/larval hindgut

, pharyngeal muscle

" " embryonic stage | stage >=14 , embryonic stage | stage 16 , embryonic stage | >=stage 14 , pupal stage " " metathoracic segment | restricted

, mesothoracic segment | restricted

, embryonic/larval midgut

, embryonic/larval somatic muscle

, pharyngeal muscle

, abdominal segment 1--8

, embryonic/larval hindgut

, wing

, embryonic central nervous system | restricted

" "visible,recessive,viable,poor,fertile,semidominant,dominant,lethal,memory defective,lethal - all die before end of larval stage,some die during larval stage,heat sensitive,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of P-stage,some die during pharate adult stage,somatic clone,wild-type,decreased cell size,cell autonomous,lethal - all die before end of pupal stage,some die during pupal stage,courtship behavior defective,locomotor behavior defective" "wing,wing vein,ectopic,trachea,wing cell,embryonic/larval tracheal system,somatic clone,tracheal metamere 3,wing vein L3 & sensillum campaniformium,sensillum campaniformium,wing & macrochaeta,macrochaeta,wing sensillum,tarsal segment,femur,rhabdomere,submarginal cell,wing disc,embryonic/first instar larval cuticle,cephalopharyngeal skeleton,presumptive embryonic/larval tracheal system,cell non-autonomous,border follicle cell,follicle cell & actin filament | somatic clone,chaeta" FBgn0263977 Tim17b Translocase of the inner mitochondrial membrane 17b http://flybase.org/reports/FBgn0263977 protein_coding_gene protein channel activity ; GO:0015266 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000050380 protein import into mitochondrial matrix ; GO:0030150 | inferred from biological aspect of ancestor with PANTHER:PTN000050380 protein targeting to mitochondrion ; GO:0006626 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from direct assay integral component of mitochondrial inner membrane ; GO:0031305 | inferred from biological aspect of ancestor with PANTHER:PTN000050380 mitochondrial inner membrane presequence translocase complex ; GO:0005744 | inferred from biological aspect of ancestor with PANTHER:PTN000050380 "Tim17b, CG40451" IPR003397:Mitochondrial inner membrane translocase subunit Tim17/Tim22/Tim23/peroxisomal protein PMP24 CG40451 27-Aug-18 DroID_v2018_08 "Drer\timm17a, Drer\timm17b" Scer\TIM17 "Cele\D2096.1, Cele\E04A4.5" Xtro\timm17a "Mmus\Timm17b, Mmus\Timm17a" "Hsap\TIMM17B, Hsap\TIMM17A" "increased cell death,lethal - all die before end of embryonic stage,some die during embryonic stage" mitochondrionunspecified FBgn0000233 btd buttonhead http://flybase.org/reports/FBgn0000233 - protein_coding_gene "transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | inferred from direct assay transcription factor binding ; GO:0008134 | inferred from physical interaction with Taf4 inferred from physical interaction with Taf2 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from direct assay inferred from genetic interaction with HGNC:11205" posterior head segmentation ; GO:0035289 | traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype cephalic furrow formation ; GO:0007376 | inferred from mutant phenotype imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype anterior head segmentation ; GO:0035288 | traceable author statement nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001145452 "btd, BTD, CG12653, Btd, buttonhead" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR015943:WD40/YVTN repeat-like-containing domain" CG12653 27-Aug-18 DroID_v2018_08 "Drer\zgc:153115, Drer\sp3b, Drer\zgc:77358, Drer\sp9, Drer\sp3a, Drer\klf13, Drer\sp5l, Drer\sp2, Drer\sp4, Drer\sp1, Drer\klf11b, Drer\sp5b, Drer\sp7, Drer\sp8a, Drer\sp8b, Drer\sp5a" "Scer\FZF1, Scer\ACE2, Scer\MOT3, Scer\SWI5, Scer\CRZ1" "Cele\sptf-1, Cele\sptf-3, Cele\sptf-2" "Xtro\sp4, Xtro\sp5l, Xtro\sp2, Xtro\sp7, Xtro\sp5, Xtro\sp1, Xtro\sp6, Xtro\sp3" "Mmus\Sp6, Mmus\Sp9, Mmus\Sp5, Mmus\Sp4, Mmus\Sp7, Mmus\Egr1, Mmus\Egr4, Mmus\Klf13, Mmus\Sp1, Mmus\Sp8, Mmus\Egr3, Mmus\Zfp526, Mmus\Egr2, Mmus\Sp2" "Hsap\EGR1, Hsap\ZNF526, Hsap\SP7, Hsap\SP8, Hsap\EGR3, Hsap\SP9, Hsap\SP6, Hsap\SP4, Hsap\SP1, Hsap\SP5, Hsap\SP2, Hsap\SP3, Hsap\KLF13" " embryonic stage | embryonic cycle 12-14 , embryonic stage | blastoderm , embryonic stage | late , embryonic stage , embryonic stage | mid , embryonic stage | stage 3,4 , embryonic stage | stage 6,7 , embryonic stage | stage 5 , embryonic stage | stage 7-17 " " organism | 60-80% egg length

, embryonic intercalary segment | precursor

, ventral nerve cord | restricted

, embryonic deuterocerebrum | precursor

, embryonic mandibular segment | precursor

, organism | striped

, embryonic peripheral nervous system | restricted

, embryonic head | restricted

, cephalic furrow | anterior to

, leg | precursor

, organism | 70-80% egg length

, neuroblast

, procephalic neurogenic region | restricted

" "wild-type,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,visible,homeotic,somatic clone,viable" "papilla organ,antennal segment,mandibular segment,antenna,cephalopharyngeal skeleton,ventral,embryo,embryonic abdominal segment,embryonic head & sclerite | ectopic,embryonic head,embryonic mandibular segment,embryonic intercalary segment,embryonic antennal segment,abdominal 1 lateral pentascolopidial chordotonal organ lch5,abdominal 2 lateral pentascolopidial chordotonal organ lch5,abdominal 3 lateral pentascolopidial chordotonal organ lch5,abdominal 4 lateral pentascolopidial chordotonal organ lch5,abdominal 5 lateral pentascolopidial chordotonal organ lch5,abdominal 6 lateral pentascolopidial chordotonal organ lch5,abdominal 7 lateral pentascolopidial chordotonal organ lch5,cephalic furrow,associated organ,dorsolateral papilla,embryonic/larval optic lobe,antennal sense organ,lateropharyngeal organ,maxillary segment,anterior,scolopidium,deuterocerebral neuromere,tritocerebral neuromere,intercalary segment,anterior pharyngeal organ,Keilin's organ,embryonic Malpighian tubule,femur,somatic clone - Minute background,tibia,eye,ectopic,wing,haltere,leg,somatic clone,wing margin bristle,distal,proximal" FBgn0005626 ple pale http://flybase.org/reports/FBgn0005626 "FBgn0003109, FBgn0003692" protein_coding_gene "tyrosine 3-monooxygenase activity ; GO:0004511 | inferred from electronic annotation with InterPro:IPR005962 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001273, InterPro:IPR018301 tyrosine 3-monooxygenase activity ; GO:0004511 | non-traceable author statement tyrosine 3-monooxygenase activity ; GO:0004511 | traceable author statement" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001273, InterPro:IPR005962, InterPro:IPR018301, InterPro:IPR019773, InterPro:IPR019774 aromatic amino acid family metabolic process ; GO:0009072 | inferred from electronic annotation with InterPro:IPR001273, InterPro:IPR018301 dopamine biosynthetic process ; GO:0042416 | inferred from mutant phenotype male courtship behavior ; GO:0008049 | inferred from mutant phenotype catecholamine metabolic process ; GO:0006584 | non-traceable author statement developmental pigmentation ; GO:0048066 | traceable author statement cuticle pigmentation ; GO:0048067 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from mutant phenotype dopamine metabolic process ; GO:0042417 | inferred from mutant phenotype courtship behavior ; GO:0007619 | non-traceable author statement regulation of adult chitin-containing cuticle pigmentation ; GO:0048082 | inferred from mutant phenotype inferred from genetic interaction with Ask1 thermotaxis ; GO:0043052 | inferred from mutant phenotype regulation of epithelial cell migration, open tracheal system ; GO:2000274 | inferred from mutant phenotype thermosensory behavior ; GO:0040040 | inferred from mutant phenotype adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype response to wounding ; GO:0009611 | inferred from expression pattern adult chitin-containing cuticle pigmentation ; GO:0048085 | inferred from mutant phenotype" - "TH, DTH, Pale, CG10118, Th, VII, DH65B, pale, dTH65B, ple, pale/ple, th, dTH1, Ple" "IPR018301:Aromatic amino acid hydroxylase, iron/copper binding site, IPR001273:Aromatic amino acid hydroxylase, IPR005962:Tyrosine 3-monooxygenase, IPR019774:Aromatic amino acid hydroxylase, C-terminal, IPR019773:Tyrosine 3-monooxygenase-like" CG10118 27-Aug-18 DroID_v2018_08 "Drer\tph2, Drer\th2, Drer\tph1b, Drer\tph1a, Drer\pah, Drer\th" - "Cele\cat-2, Cele\tph-1, Cele\pah-1" "Xtro\tph1, Xtro\pah, Xtro\th" "Mmus\Th, Mmus\Tph1, Mmus\Tph2, Mmus\Pah" "Hsap\TH, Hsap\PAH, Hsap\TPH1, Hsap\TPH2" " adult stage , larval stage && adult stage , larval stage | third instar , larval stage , larval stage | first instar " " adult abdomen

, adult brain

, central nervous system

, adult head

, adult thorax

, epidermis

, larval central nervous system

" "visual behavior defective,phototaxis defective,locomotor rhythm defective,sleep defective,hypoactive,smell perception defective,gravitaxis defective,wild-type,lethal,recessive,heat sensitive,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,somatic clone,body color defective,thermotaxis behavior defective,dominant,locomotor behavior defective,courtship behavior defective,feeding behavior defective,long lived,drug conditional,memory defective,viable" "wing,embryonic/larval tracheal system,embryonic/larval dorsal trunk,embryonic/first instar larval cuticle,cephalopharyngeal skeleton,adult cuticle,somatic clone,microchaeta,mouth hooks,cuticle,spiracle,macrochaeta,serotonergic neuron,wing cell,adult abdomen,adult thorax,dopaminergic neuron,drug conditional,mesothoracic tergum" DRSC11383 IEK 0.763470174 -1.621909565 -1.525471935 -2.188261945 -2.821184033 -3.427405512 FBgn0052671 Rab9Fa Rab at 9Fa http://flybase.org/reports/FBgn0052671 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579, InterPro:IPR005225 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11" endocytic recycling ; GO:0032456 | inferred from biological aspect of ancestor with PANTHER:PTN001178320 vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 endosome membrane ; GO:0010008 | inferred from biological aspect of ancestor with PANTHER:PTN001178320 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN001178320 vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 "DmRabX3, CG2532, Rab9Fa, CG32671, RabX3" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG32671 27-Aug-18 DroID_v2018_08 "Drer\rab35a, Drer\si:dkey-16l2.16, Drer\rab19, Drer\zgc:171927, Drer\zgc:101559, Drer\rsg1, Drer\rabl6a, Drer\rab1aa, Drer\rab33ba, Drer\rab1ba, Drer\rab43, Drer\rab33a, Drer\rab1ab, Drer\rab35b, Drer\rab1bb, Drer\rabl6b" "Scer\TEM1, Scer\YPT1" "Cele\rab-28, Cele\rab-35" "Xtro\rabl6, Xtro\rab33a, Xtro\rab28, Xtro\rab19, Xtro\rab33b, Xtro\rab1a" "Mmus\Rab33b, Mmus\Rabl6, Mmus\Rab35, Mmus\Rab1b, Mmus\Rab43, Mmus\Rab1a, Mmus\Rsg1, Mmus\Rab28, Mmus\Rab19, Mmus\Rab33a" "Hsap\RAB33A, Hsap\RAB33B, Hsap\RAB28, Hsap\RAB19, Hsap\RAB1A, Hsap\RABL6, Hsap\RSG1, Hsap\RAB1B, Hsap\RAB43, Hsap\RAB35" FBgn0024545 l(3)L3130 lethal (3) L3130 http://flybase.org/reports/FBgn0024545 - gene - - - l(3)L3130 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0061129 l(3)S003003a lethal (3) S003003a http://flybase.org/reports/FBgn0061129 gene - - - "l(3)S003003, 0030/03, l(3)S003003a" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0005371 whg whiting http://flybase.org/reports/FBgn0005371 - gene - - - whg - - 27-Aug-18 DroID_v2018_08 - - - - - - eye color defective eye FBgn0060763 l(3)S063207 lethal (3) S063207 http://flybase.org/reports/FBgn0060763 gene - - - "0632/07, l(3)S063207" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264862 asRNA:CR44053 - http://flybase.org/reports/FBgn0264862 non_protein_coding_gene - - - CR44053 - CR44053 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259933 CG42456 - http://flybase.org/reports/FBgn0259933 protein_coding_gene enzyme regulator activity ; GO:0030234 | inferred from electronic annotation with InterPro:IPR009914 dolichol metabolic process ; GO:0019348 | inferred from electronic annotation with InterPro:IPR009914 integral component of endoplasmic reticulum membrane ; GO:0030176 | inferred from electronic annotation with InterPro:IPR009914 "CG42456, Dromel_CG12016_FBtr0073063_uORF" IPR009914:Dolichol phosphate-mannose biosynthesis regulatory CG42456 27-Aug-18 DroID_v2018_08 Drer\dpm2 Scer\YIL102C-A - - Mmus\Dpm2 Hsap\DPM2 FBgn0039282 Bili Band4.1 inhibitor LRP interactor http://flybase.org/reports/FBgn0039282 protein_coding_gene molecular_function ; GO:0003674 | no biological data available regulation of establishment of protein localization ; GO:0070201 | inferred from mutant phenotype negative regulation of Wnt signaling pathway ; GO:0030178 | inferred from mutant phenotype cytoskeleton ; GO:0005856 | inferred from electronic annotation with InterPro:IPR000299 plasma membrane ; GO:0005886 | colocalizes_with inferred from direct assay "Bili, CG11848, dBili" "IPR000299:FERM domain, IPR014352:FERM/acyl-CoA-binding protein, 3-helical bundle, IPR019748:FERM central domain, IPR019749:Band 4.1 domain, IPR011993:PH domain-like" CG11848 27-Aug-18 DroID_v2018_08 "Drer\krit1, Drer\frmd8" - "Cele\kri-1, Cele\frm-10" Xtro\frmd8 "Mmus\Krit1, Mmus\Frmd8" "Hsap\KRIT1, Hsap\FRMD8" "viable,fertile" embryonic/first instar larval cuticle DRSC14405 IE 2.30752901 1.149307697 4.38860131 -0.530758612 1.121567693 0.456002575 FBgn0264001 bru3 bruno 3 http://flybase.org/reports/FBgn0264001 protein_coding_gene RNA binding ; GO:0003723 | inferred from direct assay mRNA binding ; GO:0003729 | inferred from sequence or structural similarity protein homodimerization activity ; GO:0042803 | inferred from direct assay negative regulation of translation ; GO:0017148 | inferred from sequence alignment with bru1 protein complex ; GO:0043234 | inferred from direct assay "CG43744, bruno-3, CG10046, CG12478, Dm Bru-3, cg12478, cg10046, Bru-3, l(3)05871, CG34243, bru-3, bru3" IPR000504:RNA recognition motif domain CG43744 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-205h23.2, Drer\celf3b, Drer\zgc:165603, Drer\celf5b, Drer\hug, Drer\celf2, Drer\celf1, Drer\celf5a, Drer\celf3a, Drer\celf4" - "Cele\unc-75, Cele\etr-1" "Xtro\celf1, Xtro\celf3, Xtro\celf4, Xtro\celf5, Xtro\celf2" "Mmus\Celf6, Mmus\Celf4, Mmus\Celf3, Mmus\Celf2, Mmus\Celf5, Mmus\Celf1" "Hsap\CELF3, Hsap\CELF6, Hsap\CELF2, Hsap\CELF4, Hsap\CELF1, Hsap\CELF5" DRSC22732 K -0.392388607 0.492353085 0.415812704 0.672242204 1.642179667 1.863616238 FBgn0259390 C403 - http://flybase.org/reports/FBgn0259390 gene - - - C403 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing,wing margin,chaeta,ectopic" FBgn0050340 CG30340 - http://flybase.org/reports/FBgn0050340 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from electronic annotation with InterPro:IPR000276 neuropeptide receptor activity ; GO:0008188 | inferred from sequence model G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR000276 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR017452 integral component of membrane ; GO:0016021 | inferred from sequence model" "BG:BACR48G21.1, BACR48G21.1, CG30340" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG30340 27-Aug-18 DroID_v2018_08 "Drer\mtnr1bb, Drer\mtnr1al, Drer\mtnr1c, Drer\mtnr1ab, Drer\mtnr1aa, Drer\mtnr1ba" - "Cele\npr-35, Cele\npr-5, Cele\npr-12, Cele\npr-8, Cele\npr-11" "Xtro\mtnr1c, Xtro\mtnr1b, Xtro\LOC100486065" "Mmus\Gpr50, Mmus\Mtnr1b, Mmus\Gpr3, Mmus\Mtnr1a" "Hsap\GPR3, Hsap\MTNR1B, Hsap\MTNR1A, Hsap\GPR50" "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0038386 CG5478 - http://flybase.org/reports/FBgn0038386 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG5478 - CG5478 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0069990 BG01954 BG01954 http://flybase.org/reports/FBgn0069990 gene - - - BG01954 - - 27-Aug-18 DroID_v2018_08 - - - - - - stress response defective FBgn0043979 Su(tor)293-12-3 Su(tor)293-12-3 http://flybase.org/reports/FBgn0043979 gene - - - "293-12-3, Su(tor)293-12-3" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0053201 CG33201 - http://flybase.org/reports/FBgn0053201 protein_coding_gene - - - CG33201 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060308 l(3)S148214 lethal (3) S148214 http://flybase.org/reports/FBgn0060308 gene - - - "1482/14, l(3)S148214" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0259258 EP-165 - http://flybase.org/reports/FBgn0259258 gene - - - EP-165 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing vein,wing" FBgn0020652 HIF Hypoxia Inducible Factor http://flybase.org/reports/FBgn0020652 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "HIF-1, HIF-D, Hif-1, HIF" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051634 Oatp26F Organic anion transporting polypeptide 26F http://flybase.org/reports/FBgn0051634 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from sequence or structural similarity with Oatp58Db active transmembrane transporter activity ; GO:0022804 | inferred from sequence or structural similarity with Oatp58Db organic substance transport ; GO:0071702 | inferred from sequence or structural similarity with Oatp58Db integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity with Oatp58Db "CG31634, oatp 26F, CG18784, CG13767, CG11332, Oatp26F, oatp26F" "IPR004156:Organic anion transporter polypeptide OATP, IPR002350:Kazal domain, IPR020846:Major facilitator superfamily domain" CG31634 27-Aug-18 DroID_v2018_08 "Drer\slco1f2, Drer\LOC570448, Drer\slco1f3, Drer\slco1f4, Drer\slco4a1, Drer\LOC100536648, Drer\slco2b1, Drer\slco5a1, Drer\slco3a1, Drer\LOC101883455, Drer\slco1c1" - "Cele\K02G10.5, Cele\Y70G10A.3, Cele\F53B1.8" "Xtro\slco3a1, Xtro\slco5a1, Xtro\slco2a1, Xtro\slco1b3, Xtro\slco4a1, Xtro\slco4c1" "Mmus\Slco1b2, Mmus\Slco6d1, Mmus\Slco1a1, Mmus\Slco2b1, Mmus\Slco1a4, Mmus\Slco1c1, Mmus\Slco1a5, Mmus\Slco4c1, Mmus\Gm6614, Mmus\Slco4a1, Mmus\Slco1a6, Mmus\Gm5724, Mmus\Slco5a1, Mmus\Slco2a1, Mmus\Slco6c1, Mmus\Slco3a1" "Hsap\SLCO4A1, Hsap\SLCO1B7, Hsap\SLCO4C1, Hsap\SLCO6A1, Hsap\SLCO2A1, Hsap\SLCO1B3, Hsap\SLCO1A2, Hsap\SLCO5A1, Hsap\SLCO1B1, Hsap\SLCO1C1, Hsap\SLCO3A1, Hsap\SLCO2B1" viable FBgn0027254 l(1)G0249 lethal (1) G0249 http://flybase.org/reports/FBgn0027254 - gene - - - l(1)G0249 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0265512 mlt mulet http://flybase.org/reports/FBgn0265512 protein_coding_gene molecular_function ; GO:0003674 | no biological data available spermatid development ; GO:0007286 | inferred from mutant phenotype sperm individualization ; GO:0007291 | inferred from mutant phenotype positive regulation of microtubule depolymerization ; GO:0031117 | inferred from mutant phenotype axoneme ; GO:0005930 | inferred from direct assay "CG12214, mlt, ms(2)4210, ms(2)ry3, ms(2)ry-3, ms(2)3, Tbcel, TBCE-like, TBCEL" "IPR032675:Leucine-rich repeat domain, L domain-like, IPR029071:Ubiquitin-related domain, IPR000626:Ubiquitin domain" CG12214 27-Aug-18 DroID_v2018_08 "Drer\tbcelb, Drer\tbcela, Drer\tbce" Scer\PAC2 "Cele\coel-1, Cele\tbce-1" Xtro\tbcel "Mmus\Tbce, Mmus\Tbcel" "Hsap\TBCE, Hsap\TBCEL" DRSC27515 K 0.371158683 0.177647002 -0.25916353 -0.37351947 -0.13896648 1.745850798 FBgn0046329 l(2)38Ca lethal (2) 38Ca http://flybase.org/reports/FBgn0046329 gene - - - l(2)38Ca - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0027581 CG6191 - http://flybase.org/reports/FBgn0027581 - protein_coding_gene - regulation of cell cycle ; GO:0051726 | inferred from electronic annotation with InterPro:IPR012388 phagocytosis ; GO:0006909 | inferred from mutant phenotype regulation of imaginal disc-derived wing size ; GO:0044719 | inferred from mutant phenotype - "BcDNA:GH06193, CG6191, Dromel_CG6191_FBtr0087678_mORF" "IPR012388:CDK5 and ABL1 enzyme substrate 1/2, IPR015943:WD40/YVTN repeat-like-containing domain, IPR006671:Cyclin, N-terminal, IPR013763:Cyclin-like" CG6191 27-Aug-18 DroID_v2018_08 "Drer\cables2a, Drer\cables2b, Drer\cables1" - Cele\Y71F9B.6 "Xtro\cables1, Xtro\cables2" "Mmus\Cables2, Mmus\Cables1" "Hsap\CABLES1, Hsap\CABLES2" "viable,fertile,size defective" "wing,posterior" FBgn0035425 CG17746 - http://flybase.org/reports/FBgn0035425 protein_coding_gene cation binding ; GO:0043169 | inferred from electronic annotation with InterPro:IPR000222 protein serine/threonine phosphatase activity ; GO:0004722 | inferred from electronic annotation with InterPro:IPR015655 phosphoprotein phosphatase activity ; GO:0004721 | inferred from sequence or structural similarity with MGI:MGI:99878 protein serine/threonine phosphatase activity ; GO:0004722 | non-traceable author statement protein dephosphorylation ; GO:0006470 | non-traceable author statement protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with MGI:MGI:99878 cytosol ; GO:0005829 | inferred from sequence or structural similarity with MGI:MGI:99878 "CG17746, PP2C, Cg17746" "IPR000222:PPM-type phosphatase, divalent cation binding, IPR001932:PPM-type phosphatase domain, IPR015655:Protein phosphatase 2C family" CG17746 27-Aug-18 DroID_v2018_08 "Drer\ppm1bb, Drer\ppm1nb, Drer\ppm1g, Drer\ppm1aa, Drer\ppm1ab, Drer\ppm1ba, Drer\ppm1na, Drer\ppm1f" "Scer\PTC1, Scer\PTC2, Scer\PTC3, Scer\PTC4" "Cele\fem-2, Cele\ppm-1, Cele\F42G9.1, Cele\ppm-2" "Xtro\ppm1b, Xtro\ppm1a" "Mmus\Ppm1g, Mmus\Tab1, Mmus\Ppm1f, Mmus\Ppm1n, Mmus\Ppm1b, Mmus\Ppm1e, Mmus\Ppm1a" "Hsap\PPM1E, Hsap\PPM1A, Hsap\PPM1F, Hsap\TAB1, Hsap\PPM1G, Hsap\PPM1N, Hsap\PPM1B" "viable,fertile,lethal" DRSC08521 E 0.012788365 1.009485774 0.993251345 1.900285157 -0.374090839 -0.240521204 FBgn0060825 l(3)S051303 lethal (3) S051303 http://flybase.org/reports/FBgn0060825 gene - - - "0513/03, l(3)S051303" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0065302 l(2)SH1985 lethal (2) SH1985 http://flybase.org/reports/FBgn0065302 gene - - - "l(2)SH1985, l(2)SH2 1985" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0002083 l(2)49Fl lethal (2) 49Fl http://flybase.org/reports/FBgn0002083 - gene - - - "vr-15, l(2)vr15, l(2)49Fl" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive,heat sensitive,non-suppressor of variegation,dominant" FBgn0016744 Su(Raf)3C Su(Raf)3C http://flybase.org/reports/FBgn0016744 - gene - - - Su(Raf)3C - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0026647 l(2)8bb lethal (2) 8bb http://flybase.org/reports/FBgn0026647 - gene - - - "8bb, l(2)8bb" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0265737 lncRNA:CR44544 - http://flybase.org/reports/FBgn0265737 non_protein_coding_gene - - - "CR44544, incRNA.494, lincRNA.494" - CR44544 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0011770 Gip GIP-like http://flybase.org/reports/FBgn0011770 - protein_coding_gene hydroxypyruvate isomerase activity ; GO:0008903 | inferred from sequence or structural similarity with UniProtKB:P30147 glyoxylate metabolic process ; GO:0046487 | inferred from sequence or structural similarity with UniProtKB:P30147 extracellular region ; GO:0005576 | inferred from direct assay "CG2227, T15, Gip, gene C" "IPR013022:Xylose isomerase-like, TIM barrel domain, IPR026040:Hydroxypyruvate isomerase-like" CG2227 27-Aug-18 DroID_v2018_08 Drer\hyi - Cele\C05D11.5 Xtro\hyi Mmus\Hyi Hsap\HYI viable FBgn0011909 tRNA:Leu-CAA-2-1 transfer RNA:Leucine-CAA 2-1 http://flybase.org/reports/FBgn0011909 "FBgn0003789, FBgn0052840, FBgn0052841, FBgn0060163" tRNA_gene UUG codon-amino acid adaptor activity ; GO:0033404 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033404 cytosol ; GO:0005829 | inferred by curator from GO:0033404 "CR32841, tRNA[Leu], DtL[a], leu-a, AE002787.trna17-LeuCAA, tRNA:L:CAA:AE002787-a, tRNA:leu3:49Fa, CR32840, tRNA[LEU], chr2R.trna76-LeuCAA, tRNA-Leu-CAA-2-1, tRNA:Leu-CAA-2-1, tRNA:L3:49Fa, UUG" - CR32841 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040239 bc10 bc10 http://flybase.org/reports/FBgn0040239 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "dbc10, CG4867, bc10" IPR009598:Bladder cancer-related BC10 CG4867 27-Aug-18 DroID_v2018_08 Drer\blcap - Cele\Y73E7A.6 Xtro\blcap Mmus\Blcap Hsap\BLCAP viable FBgn0002720 mesA messy A http://flybase.org/reports/FBgn0002720 - gene - - - "messy, mes-A, l(3)mes-1A, mesA" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,visible,partially lethal - majority die,sterile" "head bristle,adult thorax & macrochaeta,anterior scutellar bristle,wing,posterior crossvein" FBgn0017422 anon-70Cb anon-70Cb http://flybase.org/reports/FBgn0017422 - gene - - - "t3, anon-70Cb" - - 27-Aug-18 DroID_v2018_08 - - - - - - embryonic stage && larval stage && pupal stage FBgn0025775 l(2)37Ad lethal (2) 37Ad http://flybase.org/reports/FBgn0025775 - gene - - - "l(2)02660, l(2)02660r, l(2)37Ad" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0033868 S-Lap7 Sperm-Leucylaminopeptidase 7 http://flybase.org/reports/FBgn0033868 protein_coding_gene "aminopeptidase activity ; GO:0004177 | inferred from electronic annotation with InterPro:IPR000819, InterPro:IPR008283, InterPro:IPR011356 metalloexopeptidase activity ; GO:0008235 | inferred from electronic annotation with InterPro:IPR011356 manganese ion binding ; GO:0030145 | inferred from electronic annotation with InterPro:IPR011356" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000819, InterPro:IPR008283 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern" cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR011356 extracellular space ; GO:0005615 | inferred from direct assay "CG13340, S-Lap7, S-LAP 7" "IPR000819:Peptidase M17, leucyl aminopeptidase, C-terminal, IPR008283:Peptidase M17, leucyl aminopeptidase, N-terminal, IPR011356:Peptidase M17, leucine aminopeptidase/peptidase B" CG13340 27-Aug-18 DroID_v2018_08 "Drer\zgc:152830, Drer\lap3, Drer\npepl1, Drer\rfwd2" - Cele\lap-1 "Xtro\lap3, Xtro\rfwd2" "Mmus\Rfwd2, Mmus\Npepl1, Mmus\Lap3" "Hsap\LAP3, Hsap\NPEPL1" FBgn0263268 del3 - http://flybase.org/reports/FBgn0263268 gene - gonad development ; GO:0008406 | inferred from mutant phenotype - del3 - - 27-Aug-18 DroID_v2018_08 - - - - - - gonad FBgn0267029 lncRNA:CR45473 - http://flybase.org/reports/FBgn0267029 non_protein_coding_gene - - - CR45473 - CR45473 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0027508 Tnks tankyrase http://flybase.org/reports/FBgn0027508 FBgn0039351 protein_coding_gene scaffold protein binding ; GO:0097110 | inferred from physical interaction with Axn NAD+ ADP-ribosyltransferase activity ; GO:0003950 | inferred from direct assay positive regulation of telomere maintenance via telomerase ; GO:0032212 | inferred from electronic annotation with InterPro:IPR028731 Wnt signaling pathway ; GO:0016055 | inferred from electronic annotation with InterPro:IPR028731 spindle assembly ; GO:0051225 | inferred from electronic annotation with InterPro:IPR028731 protein ADP-ribosylation ; GO:0006471 | inferred from direct assay chaeta development ; GO:0022416 | inferred from genetic interaction with Ssdp inferred from genetic interaction with Chi regulation of proteasome assembly ; GO:0090364 | inferred from direct assay wing disc development ; GO:0035220 | inferred from genetic interaction with Bx - "BcDNA:LD22548, CG17487, CG4719, tankyrase, Dm.pARTb, Tnks, dTNKS, DTNKS, TNKS, Tankyrase, dARTD5, dTANK" "IPR001660:Sterile alpha motif domain, IPR002110:Ankyrin repeat, IPR012317:Poly(ADP-ribose) polymerase, catalytic domain, IPR013761:Sterile alpha motif/pointed domain, IPR020683:Ankyrin repeat-containing domain, IPR028731:Tankyrase-1, IPR015943:WD40/YVTN repeat-like-containing domain" CG4719 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-86e18.2, Drer\ankdd1a, Drer\tnksb, Drer\ank1b, Drer\pidd1, Drer\si:ch73-193i2.2, Drer\ank3a, Drer\psmd10, Drer\ankef1b, Drer\tnksa, Drer\si:ch73-252i11.1, Drer\trpn1, Drer\si:ch211-203b8.6, Drer\ankef1a, Drer\hace1, Drer\ankdd1b, Drer\ank3b, Drer\ank2a" Scer\NAS6 "Cele\F40G9.17, Cele\trp-4, Cele\K02B12.5" "Xtro\ank3, Xtro\LOC100492885, Xtro\tnks2, Xtro\ankdd1a, Xtro\tnks, Xtro\ankef1, Xtro\cat2, Xtro\parp14.3, Xtro\hace1, Xtro\ank1, Xtro\asb7, Xtro\ank2" "Mmus\Asb7, Mmus\Ankrd44, Mmus\Ankrd53, Mmus\Ank2, Mmus\Ank1, Mmus\Ankrd61, Mmus\Ankdd1b, Mmus\Ankef1, Mmus\Hace1, Mmus\Ankrd42, Mmus\Ankdd1a, Mmus\Pidd1, Mmus\Rnasel, Mmus\Ankrd60, Mmus\Tiparp, Mmus\Tnks, Mmus\Ankrd65, Mmus\Tnks2, Mmus\Ank3, Mmus\Psmd10" "Hsap\ANKDD1B, Hsap\ANK2, Hsap\ANKDD1A, Hsap\ANKRD61, Hsap\ANKRD60, Hsap\ASB7, Hsap\ANKRD65, Hsap\ANKRD53, Hsap\ANKEF1, Hsap\TNKS2, Hsap\ANK3, Hsap\PIDD1, Hsap\HACE1, Hsap\TNKS, Hsap\ANK1, Hsap\TIPARP, Hsap\PSMD10, Hsap\RNASEL" viable FBgn0260334 GSd414 - http://flybase.org/reports/FBgn0260334 gene - - - GSd414 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0010587 l(2)04884 lethal (2) 04884 http://flybase.org/reports/FBgn0010587 - gene - - - l(2)04884 - - 27-Aug-18 DroID_v2018_08 - - - - - - partially lethal - majority die FBgn0036186 CG6071 - http://flybase.org/reports/FBgn0036186 protein_coding_gene peptide binding ; GO:0042277 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 metalloaminopeptidase activity ; GO:0070006 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 peptide catabolic process ; GO:0043171 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 extracellular space ; GO:0005615 | inferred from direct assay CG6071 "IPR024571:ERAP1-like C-terminal domain, IPR001930:Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR014782:Peptidase M1, membrane alanine aminopeptidase, N-terminal" CG6071 27-Aug-18 DroID_v2018_08 "Drer\anpepa, Drer\erap1a, Drer\lnpep, Drer\erap2, Drer\enpep, Drer\erap1b, Drer\npepps, Drer\si:ch211-149p5.1, Drer\si:ch211-198g19.1, Drer\anpepb, Drer\si:ch211-276a23.5, Drer\si:ch211-106j24.1" "Scer\APE2, Scer\AAP1, Scer\TMA108" "Cele\R03G8.4, Cele\AC3.5, Cele\T12E12.6, Cele\Y67D8C.9, Cele\T07F10.1, Cele\T16G12.1, Cele\Y53F4B.20, Cele\VB0395L.1, Cele\mnp-1, Cele\F49B2.6, Cele\pam-1, Cele\R03G8.6, Cele\Y42A5A.1" "Xtro\lnpep, Xtro\lvrn, Xtro\anpep, Xtro\enpep, Xtro\npepps, Xtro\erap1" "Mmus\Anpep, Mmus\Npepps, Mmus\Lvrn, Mmus\Enpep, Mmus\Trhde, Mmus\Erap1, Mmus\Lnpep" "Hsap\ANPEP, Hsap\ERAP1, Hsap\ENPEP, Hsap\ERAP2, Hsap\TRHDE, Hsap\LNPEP, Hsap\NPEPPS, Hsap\LVRN" viable FBgn0000632 fap female abdomen pattern http://flybase.org/reports/FBgn0000632 - gene - - - fap - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,female,recessive,body color defective" "abdominal tergite 6,abdominal tergite 7" FBgn0016702 Ras85D::Src64B Ras85D::Src64B http://flybase.org/reports/FBgn0016702 - engineered_fusion_gene - - - Ras85D::Src64B - - 27-Aug-18 DroID_v2018_08 - - - - - - "photoreceptor cell R7,eye" FBgn0000302 cha chaff http://flybase.org/reports/FBgn0000302 - gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available cha - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "embryonic/first instar larval cuticle,maternal effect,embryonic head" FBgn0085673 Su(Ste):CR41533 - http://flybase.org/reports/FBgn0085673 non_protein_coding_gene - - - "CG41533, CR41533, Su(Ste):CR41533, Su(Ste)" - CR41533 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0019623 Crlbp Chemical-sense-related lipophilic-ligand-binding protein http://flybase.org/reports/FBgn0019623 - gene - - - Crlbp - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0069229 gl(2L)343-11 gl(2L)343-11 http://flybase.org/reports/FBgn0069229 gene molecular_function ; GO:0003674 | no biological data available "anterior/posterior axis specification, embryo ; GO:0008595 | inferred from mutant phenotype" cellular_component ; GO:0005575 | no biological data available gl(2L)343-11 - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage,maternal effect" "embryonic head,germline clone,maternal effect" FBgn0004938 ABO-YL Abnormal Oocyte on YL http://flybase.org/reports/FBgn0004938 - region - - - "ABO, ABO-YL" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004023 wrl whirligig http://flybase.org/reports/FBgn0004023 - gene - microtubule-based process ; GO:0007017 | inferred from mutant phenotype sperm axoneme assembly ; GO:0007288 | inferred from mutant phenotype - "nc4, ms(3)nc4, EcRms4, wrl" - - 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,dominant,recessive,viable" spermatid axoneme FBgn0030621 CG15030 - http://flybase.org/reports/FBgn0030621 protein_coding_gene - - - CG15030 - - 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC19611 I 1.682582919 -1.125804612 -0.837113938 0.438017978 0.149972023 0.519726808 FBgn0022812 E(faf)E306 Enhancer of faf E306 http://flybase.org/reports/FBgn0022812 - gene - - - E(faf)E306 - - 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0030687 CG17209 - http://flybase.org/reports/FBgn0030687 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR000722, InterPro:IPR006592, InterPro:IPR007066, InterPro:IPR007080, InterPro:IPR007081, InterPro:IPR007083 RNA polymerase III activity ; GO:0001056 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000453624" "transcription, DNA-templated ; GO:0006351 | inferred from electronic annotation with InterPro:IPR000722, InterPro:IPR006592, InterPro:IPR007066, InterPro:IPR007080, InterPro:IPR007081, InterPro:IPR007083" DNA-directed RNA polymerase III complex ; GO:0005666 | inferred from biological aspect of ancestor with PANTHER:PTN000453624 CG17209 "IPR000722:RNA polymerase, alpha subunit, IPR006592:RNA polymerase, N-terminal, IPR007066:RNA polymerase Rpb1, domain 3, IPR007080:RNA polymerase Rpb1, domain 1, IPR007081:RNA polymerase Rpb1, domain 5, IPR007083:RNA polymerase Rpb1, domain 4" CG17209 27-Aug-18 DroID_v2018_08 "Drer\polr2a, Drer\ubxn7, Drer\polr3a" "Scer\RPO21, Scer\RPO31" Cele\rpc-1 "Xtro\polr3a, Xtro\ubxn7" "Mmus\Polr2a, Mmus\Ubxn7, Mmus\Polr3a" "Hsap\UBXN7, Hsap\POLR3A, Hsap\POLR2A" "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum DRSC19766 K -0.301337531 0.160980242 -0.963043534 0.482878275 2.135652684 -0.893814352 FBgn0034076 Jhedup Juvenile hormone esterase duplication http://flybase.org/reports/FBgn0034076 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from biological aspect of ancestor with PANTHER:PTN000168392 - - "CG8424, Jhedup, JHEdup, JHE" "IPR002018:Carboxylesterase, type B, IPR019819:Carboxylesterase type B, conserved site, IPR019826:Carboxylesterase type B, active site, IPR029058:Alpha/Beta hydrolase fold" CG8424 27-Aug-18 DroID_v2018_08 "Drer\cell, Drer\si:ch211-93f2.1, Drer\nlgn4b, Drer\nlgn4a, Drer\nlgn2b, Drer\cel.1, Drer\nlgn3b, Drer\nlgn1, Drer\ces3, Drer\ces2, Drer\nlgn2a, Drer\nlgn3a" - "Cele\K11G9.3, Cele\T28C12.5, Cele\F07C4.12, Cele\C23H4.2, Cele\C23H4.3, Cele\K11G9.2, Cele\C17H12.4, Cele\E01G6.3, Cele\Y71H2AM.13, Cele\C23H4.4, Cele\F15A8.6, Cele\T02B5.1, Cele\K07C11.4, Cele\ZK994.1, Cele\T28C12.4, Cele\C23H4.7, Cele\C52A10.2, Cele\T02B5.3, Cele\F56C11.6, Cele\F13H6.3, Cele\ZC376.3, Cele\B0238.1, Cele\ZC376.2, Cele\ZC376.1, Cele\T22D1.11, Cele\K11G9.1, Cele\C42D4.2, Cele\C52A10.1, Cele\R173.3, Cele\C01B10.4, Cele\C01B10.10" "Xtro\ces2, Xtro\cel, Xtro\nlgn2, Xtro\nlgn3, Xtro\nlgn4x, Xtro\ces3, Xtro\LOC100494782" "Mmus\Ces2c, Mmus\Ces2f, Mmus\Ces1b, Mmus\Ces2e, Mmus\Ces5a, Mmus\Nlgn3, Mmus\Ces2a, Mmus\Ces2h, Mmus\Ces1c, Mmus\Nlgn2, Mmus\Ces2b, Mmus\Ces3a, Mmus\Ces1e, Mmus\Ces3b, Mmus\Ces4a, Mmus\Cel, Mmus\Ces2g, Mmus\Ces1d, Mmus\Ces1h, Mmus\Nlgn1, Mmus\Ces1f, Mmus\Ces1g" "Hsap\CES4A, Hsap\CEL, Hsap\CES3, Hsap\CES1, Hsap\NLGN4Y, Hsap\NLGN3, Hsap\NLGN2, Hsap\CES2, Hsap\CES5A, Hsap\NLGN1, Hsap\NLGN4X" viable FBgn0053143 CG33143 - http://flybase.org/reports/FBgn0053143 protein_coding_gene - - - "CG4232, CG13509, CG33143, 33143, mdcds_16487" "IPR003961:Fibronectin type III, IPR013783:Immunoglobulin-like fold, IPR032073:Fibronectin type III domain-containing protein 5, C-terminal domain" CG33143 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085547 CG40971 - http://flybase.org/reports/FBgn0085547 protein_coding_gene - - - CG40971 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0029033 l(2)Q73 lethal (2) Q73 http://flybase.org/reports/FBgn0029033 gene - - - "Q73, l(2)Q73" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0003106 PL(3)sp-W1 Polygenic locus sternopleural W1 http://flybase.org/reports/FBgn0003106 - gene - - - "a, PL(3)sp[W1], PL(3)sp-W1" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034684 CG13501 - http://flybase.org/reports/FBgn0034684 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13501 "IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical" CG13501 27-Aug-18 DroID_v2018_08 Drer\rsph14 - - Xtro\rsph14 Mmus\Rsph14 Hsap\RSPH14 viable FBgn0038683 CG11779 - http://flybase.org/reports/FBgn0038683 protein_coding_gene chaperone binding ; GO:0051087 | inferred from biological aspect of ancestor with PANTHER:PTN000076497 P-P-bond-hydrolysis-driven protein transmembrane transporter activity ; GO:0015450 | inferred from sequence or structural similarity with UniProtKB:O43615 protein import into mitochondrial matrix ; GO:0030150 | inferred from biological aspect of ancestor with PANTHER:PTN000076497 protein targeting to mitochondrion ; GO:0006626 | inferred from sequence or structural similarity with UniProtKB:O43615 cellular response to hypoxia ; GO:0071456 | inferred from mutant phenotype mitochondrial inner membrane presequence translocase complex ; GO:0005744 | inferred from sequence or structural similarity with UniProtKB:O43615 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000076497 "BcDNA:GM03811, BEST:GM03811, CG11779, CG117799, GH-18370" "IPR007379:Tim44-like domain, IPR017303:Mitochondrial import inner membrane translocase subunit Tim44, IPR032710:NTF2-like domain" CG11779 27-Aug-18 DroID_v2018_08 Drer\timm44 Scer\TIM44 Cele\tin-44 Xtro\timm44 Mmus\Timm44 Hsap\TIMM44 "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "eye,trichogen cell,mesothoracic tergum" FBgn0028120 l(3)S060313 lethal (3) S060313 http://flybase.org/reports/FBgn0028120 gene - - - "l(3)S060313, l(3)s001813" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0025840 E(var)915 E(var)915 http://flybase.org/reports/FBgn0025840 - gene - - - "E-915, E(var)915" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0284442 Mcm3 Minichromosome maintenance 3 http://flybase.org/reports/FBgn0284442 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001208, InterPro:IPR008046, InterPro:IPR018525 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001208, InterPro:IPR008046, InterPro:IPR018525 3'-5' DNA helicase activity ; GO:0043138 | contributes_to inferred from direct assay" DNA replication initiation ; GO:0006270 | inferred from electronic annotation with InterPro:IPR008046 mushroom body development ; GO:0016319 | inferred from mutant phenotype neuroblast proliferation ; GO:0007405 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR008046 MCM complex ; GO:0042555 | inferred from electronic annotation with InterPro:IPR008046 "mcm3, smu, Mcm3, CG4206, MCM3, DmMcm3, DmMCM3, dMCM3, PCR2, Mcp-PCR2, McM3, DmeMCM3, dMcm3" "IPR033762:MCM OB domain, IPR031327:Mini-chromosome maintenance protein, IPR018525:Mini-chromosome maintenance, conserved site, IPR001208:MCM domain, IPR003593:AAA+ ATPase domain, IPR008046:DNA replication licensing factor Mcm3, IPR012340:Nucleic acid-binding, OB-fold, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR027925:MCM N-terminal domain" CG4206 27-Aug-18 DroID_v2018_08 "Drer\mcm3, Drer\mcm3l" Scer\MCM3 Cele\mcm-3 Xtro\mcm3 Mmus\Mcm3 Hsap\MCM3 " adult stage | female , egg stage | unfertilized egg , embryonic stage | 0-4 hr , embryonic stage | stage 11-12 " " unfertilized egg

, embryonic central nervous system

" "radiation sensitive,lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0026077 Gasp Gasp http://flybase.org/reports/FBgn0026077 FBgn0026290 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin binding ; GO:0008061 | inferred from reviewed computational analysis "chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | inferred from mutant phenotype regulation of tube size, open tracheal system ; GO:0035151 | inferred from mutant phenotype regulation of multicellular organism growth ; GO:0040014 | inferred from mutant phenotype" extracellular space ; GO:0005615 | inferred from direct assay "gasp, gammaBert27, anon-EST:ParkEST180, CG10287, Gasp, obst-C, 2A12" IPR002557:Chitin binding domain CG10287 27-Aug-18 DroID_v2018_08 - - "Cele\R02F2.4, Cele\dct-9, Cele\cbd-1, Cele\cpg-2" - - - viable FBgn0001983 wor worniu http://flybase.org/reports/FBgn0001983 - protein_coding_gene "nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with esg inferred from sequence or structural similarity with sna" "dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from sequence or structural similarity brain development ; GO:0007420 | inferred from mutant phenotype ventral cord development ; GO:0007419 | inferred from mutant phenotype central nervous system development ; GO:0007417 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype asymmetric neuroblast division ; GO:0055059 | inferred from genetic interaction with esg, sna" nucleus ; GO:0005634 | inferred from sequence or structural similarity "Wor, l(2)35Da, BG:DS03023.1, l(2)br35, l35Da, br35, CG4158, wor" IPR013087:Zinc finger C2H2-type CG4158 27-Aug-18 DroID_v2018_08 "Drer\scrt1b, Drer\snai1b, Drer\scrt2, Drer\si:dkeyp-113d7.10, Drer\snai3, Drer\snai2, Drer\snai1a, Drer\scrt1a" "Scer\RPH1, Scer\AZF1" Cele\snai-1 "Xtro\wt1, Xtro\snai1, Xtro\snai2" "Mmus\Scrt2, Mmus\Scrt1, Mmus\Snai3, Mmus\Zfp128, Mmus\Snai1, Mmus\Snai2" "Hsap\ZNF8, Hsap\SNAI3, Hsap\SNAI2, Hsap\SNAI1, Hsap\ZNF461, Hsap\SCRT1, Hsap\SCRT2" " embryonic stage | stage >=8 , embryonic stage | stage >=13 , embryonic stage | stage >=9 " " procephalic neurogenic region

, embryonic brain

, ventral nerve cord

, neuroblast

" "neuroanatomy defective,partially lethal - majority die,lethal,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,viable,visible" "ventral nerve cord,denticle belt,embryonic/larval brain,dorsal multidendritic neuron ddaE & dendrite,abdominal dorsal multidendritic neuron ddaE & dendrite,chaeta,supernumerary" FBgn0010137 l(2)62B10 lethal (2) of Spiess 62B10 http://flybase.org/reports/FBgn0010137 - gene - - - l(2)62B10 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0036575 CG5157 - http://flybase.org/reports/FBgn0036575 protein_coding_gene heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR018506 - - CG5157 "IPR001199:Cytochrome b5-like heme/steroid binding domain, IPR018506:Cytochrome b5, heme-binding site" CG5157 27-Aug-18 DroID_v2018_08 "Drer\fads2, Drer\cyb5b, Drer\cyb5a" "Scer\CYB2, Scer\CYB5, Scer\SCS7, Scer\OLE1" "Cele\cytb-5.1, Cele\cytb-5.2" "Xtro\cyb5b, Xtro\cyb5a" "Mmus\Cyb5a, Mmus\Cyb5d1, Mmus\Fads1, Mmus\Cyb5b" "Hsap\FADS2, Hsap\CYB5B, Hsap\CYB5A" viable FBgn0058154 CG40154 - http://flybase.org/reports/FBgn0058154 protein_coding_gene - - - CG40154 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034502 CG13871 - http://flybase.org/reports/FBgn0034502 protein_coding_gene - - - CG13871 - CG13871 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0038647 CG14302 - http://flybase.org/reports/FBgn0038647 protein_coding_gene - - - "BcDNA:LP02994, CG14302" - CG14302 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0263378 asRNA:CR43430 - http://flybase.org/reports/FBgn0263378 non_protein_coding_gene - - - CR43430 - CR43430 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0022158 l(2)k05722 lethal (2) k05722 http://flybase.org/reports/FBgn0022158 - gene - - - l(2)k05722 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0267443 lncRNA:CR45793 - http://flybase.org/reports/FBgn0267443 non_protein_coding_gene - - - "CR45793, Mgn095159" - CR45793 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0067870 Mod(Prat:bw)3-5 Mod(Prat:bw)3-5 http://flybase.org/reports/FBgn0067870 gene - - - "Mod-3-5, Mod(Prat:bw)3-5" - - 27-Aug-18 DroID_v2018_08 - - - - - - enhancer of variegation FBgn0032387 CG16965 - http://flybase.org/reports/FBgn0032387 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR005195, InterPro:IPR008928, InterPro:IPR012341" carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR005195 - CG16965 "IPR005195:Glycoside hydrolase, family 65, central catalytic, IPR008928:Six-hairpin glycosidase-like" CG16965 27-Aug-18 DroID_v2018_08 Drer\pgghg Scer\ATH1 - Xtro\athl1 Mmus\Pgghg Hsap\PGGHG viable FBgn0043557 Su(ro[DOM])2014 Su(ro[DOM])2014 http://flybase.org/reports/FBgn0043557 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with ro cellular_component ; GO:0005575 | no biological data available Su(ro[DOM])2014 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0062643 EP707 EP707 http://flybase.org/reports/FBgn0062643 gene - - - "EP(3)0707, EP707" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0082330 HM813 HM813 http://flybase.org/reports/FBgn0082330 gene - - - HM813 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002388 l(3)93Dd lethal (3) 93Dd http://flybase.org/reports/FBgn0002388 - gene - - - "er9, l(3)er9, l(3)93Dd" - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive,lethal" eye FBgn0002429 l(3)F55 lethal (3) F55 http://flybase.org/reports/FBgn0002429 - gene - - - "l(3)55, l(3)F55" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" wing FBgn0263382 lncRNA:CR43434 - http://flybase.org/reports/FBgn0263382 non_protein_coding_gene - - - CR43434 - CR43434 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0261523 CG42658 - http://flybase.org/reports/FBgn0261523 protein_coding_gene - - endoplasmic reticulum membrane ; GO:0005789 | inferred from electronic annotation with InterPro:IPR016763 CG42658 "IPR016763:Vesicle-associated membrane-protein-associated protein, IPR013783:Immunoglobulin-like fold, IPR008962:PapD-like, IPR000535:Major sperm protein (MSP) domain" CG42658 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0069304 X-86-9 X-86-9 http://flybase.org/reports/FBgn0069304 gene molecular_function ; GO:0003674 | no biological data available morphogenesis of embryonic epithelium ; GO:0016331 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available X-86-9 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage" "embryonic/first instar larval cuticle,germline clone,maternal effect,filzkorper" FBgn0022970 snRNPA snRNPA http://flybase.org/reports/FBgn0022970 - gene - - nucleus ; GO:0005634 | inferred from direct assay small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from direct assay "A, snRNPA" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0015488 l(2)46Cl lethal (2) 46Cl http://flybase.org/reports/FBgn0015488 - gene - - - "T, l(2)46Cl" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0086913 Rab26 Rab26 http://flybase.org/reports/FBgn0086913 protein_coding_gene GTP binding ; GO:0005525 | inferred from sequence or structural similarity with UniProtKB:P51156 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11 vesicle docking involved in exocytosis ; GO:0006904 | inferred from biological aspect of ancestor with PANTHER:PTN000635132 Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 protein localization to plasma membrane ; GO:0072659 | inferred from biological aspect of ancestor with PANTHER:PTN000635134 protein secretion ; GO:0009306 | inferred from biological aspect of ancestor with PANTHER:PTN000635132 regulation of exocytosis ; GO:0017157 | inferred from sequence or structural similarity with UniProtKB:P51156 vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 intrinsic component of plasma membrane ; GO:0031226 | inferred from sequence or structural similarity with UniProtKB:P51156 recycling endosome ; GO:0055037 | inferred from direct assay synaptic vesicle ; GO:0008021 | inferred from biological aspect of ancestor with PANTHER:PTN001530779 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000635134 synapse ; GO:0045202 | inferred from direct assay "rab26, AAF51708, DmRab26, CG7605, Rab26, CG32439, CG34410, Q8IPT6, Q9VP48" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain" CG34410 27-Aug-18 DroID_v2018_08 Drer\zgc:112183 Scer\SEC4 Cele\rab-37 "Xtro\rab26, Xtro\rab37" "Mmus\Rab37, Mmus\Rab26" "Hsap\RAB37, Hsap\RAB26" viable FBgn0082355 HM298 HM298 http://flybase.org/reports/FBgn0082355 gene - - - HM298 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0020881 als alae sublatae http://flybase.org/reports/FBgn0020881 - gene - - - "als, Mps1" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0016809 l(1)L10 lethal (1) L10 http://flybase.org/reports/FBgn0016809 - gene - - - "l(1)L10, L10" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0051238 CG31238 - http://flybase.org/reports/FBgn0051238 protein_coding_gene - - - CG31238 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000564 Eh Eclosion hormone http://flybase.org/reports/FBgn0000564 FBgn0026855 protein_coding_gene ecdysis-triggering hormone activity ; GO:0008255 | inferred from electronic annotation with InterPro:IPR006825 neuropeptide hormone activity ; GO:0005184 | traceable author statement eclosion hormone activity ; GO:0008031 | non-traceable author statement eclosion hormone activity ; GO:0008031 | inferred from sequence or structural similarity "neuropeptide signaling pathway ; GO:0007218 | inferred from electronic annotation with InterPro:IPR006825 eclosion ; GO:0007562 | traceable author statement regulation of eclosion ; GO:0007563 | inferred from sequence or structural similarity neuropeptide signaling pathway ; GO:0007218 | traceable author statement ecdysis, chitin-based cuticle ; GO:0018990 | inferred from mutant phenotype" extracellular space ; GO:0005615 | inferred from sequence model "EH, Drm-EH, eh, EHAB, DMEHAB, CG5400, Eh" IPR006825:Eclosion hormone CG5400 27-Aug-18 DroID_v2018_08 - - "Cele\clec-251, Cele\F11D11.6, Cele\clec-253, Cele\clec-255" - - - FBgn0030191 CG15306 - http://flybase.org/reports/FBgn0030191 protein_coding_gene microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR027328 molecular_function ; GO:0003674 | no biological data available positive regulation of JAK-STAT cascade ; GO:0046427 | inferred from mutant phenotype - CG15306 "IPR001715:Calponin homology domain, IPR027328:Microtubule-associated protein RP/EB" CG15306 27-Aug-18 DroID_v2018_08 "Drer\mapre2, Drer\mapre1a, Drer\mapre3b, Drer\mapre3a, Drer\mapre1b" "Scer\CHS5, Scer\BIM1" "Cele\ebp-1, Cele\ebp-2, Cele\ebp-3" Xtro\mapre1 "Mmus\Dmp1, Mmus\Mapre3, Mmus\Mapre2, Mmus\Mapre1" "Hsap\MAPRE3, Hsap\DMP1, Hsap\MAPRE1, Hsap\MAPRE2" viable FBgn0035170 dpr20 defective proboscis extension response 20 http://flybase.org/reports/FBgn0035170 protein_coding_gene molecular_function ; GO:0003674 | no biological data available sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with dpr1 synapse organization ; GO:0050808 | inferred from expression pattern integral component of plasma membrane ; GO:0005887 | inferred from sequence model "CG12191, Dpr-20, CT9818, dpr20, Dpr20" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR013106:Immunoglobulin V-set domain, IPR013783:Immunoglobulin-like fold, IPR013151:Immunoglobulin" CG12191 27-Aug-18 DroID_v2018_08 "Drer\LOC100333196, Drer\LOC101885444, Drer\si:ch211-264f5.6, Drer\si:dkey-65b12.12, Drer\nadl1.1" - Cele\zig-8 "Xtro\obsl1, Xtro\nfasc" - - viable FBgn0004186 snRNA:U1:95Cb small nuclear RNA U1 at 95Cb http://flybase.org/reports/FBgn0004186 "FBgn0003915, FBgn0003918" snRNA_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity" U1 snRNP ; GO:0005685 | inferred from sequence or structural similarity "U1, U1 snRNA, U1a-95Cb, U1-95.2, U1snRNA, K5, snRNA:U1, snRNA-U1-95.2, U1snRNA95Cb, CR32866, snRNA:U1:95Cb, U1:95Cb, snRNA:U1:95CB, U1-95Cb, U1:95C, 95C U1" - CR32866 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265010 Ms(3)88C Male sterile (3) 88C http://flybase.org/reports/FBgn0265010 gene - - - Ms(3)88C - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0084325 su(eas)13 su(eas)13 http://flybase.org/reports/FBgn0084325 gene - - - su(eas)13 - - 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0011661 Moe Moesin http://flybase.org/reports/FBgn0011661 "FBgn0013950, FBgn0014345, FBgn0026689, FBgn0027218, FBgn0028282, FBgn0028289, FBgn0066841, FBgn0066842, FBgn0066843, FBgn0066844" protein_coding_gene "phosphatidylinositol-4,5-bisphosphate binding ; GO:0005546 | inferred from direct assay actin binding ; GO:0003779 | non-traceable author statement actin binding ; GO:0003779 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Mer cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with conu microtubule binding ; GO:0008017 | inferred from mutant phenotype" "regulation of cell shape ; GO:0008360 | inferred from mutant phenotype positive regulation of mitotic spindle elongation ; GO:1902846 | inferred from mutant phenotype pole plasm protein localization ; GO:0007318 | traceable author statement establishment or maintenance of apical/basal cell polarity ; GO:0035088 | traceable author statement microtubule anchoring ; GO:0034453 | inferred from mutant phenotype positive regulation of endocytosis ; GO:0045807 | inferred from mutant phenotype cytoskeleton organization ; GO:0007010 | traceable author statement establishment or maintenance of polarity of larval imaginal disc epithelium ; GO:0016336 | inferred from mutant phenotype establishment or maintenance of epithelial cell apical/basal polarity ; GO:0045197 | inferred from mutant phenotype olfactory behavior ; GO:0042048 | inferred from mutant phenotype anterior/posterior pattern specification ; GO:0009952 | traceable author statement cortical actin cytoskeleton organization ; GO:0030866 | inferred from mutant phenotype lumen formation, open tracheal system ; GO:0035149 | inferred from mutant phenotype male courtship behavior, veined wing generated song production ; GO:0045433 | inferred from mutant phenotype actin filament-based process ; GO:0030029 | non-traceable author statement eye photoreceptor cell development ; GO:0042462 | traceable author statement determination of left/right symmetry ; GO:0007368 | inferred from mutant phenotype rhabdomere membrane biogenesis ; GO:0045313 | inferred from mutant phenotype cortical microtubule organization ; GO:0043622 | inferred from mutant phenotype pole plasm assembly ; GO:0007315 | traceable author statement oocyte anterior/posterior axis specification ; GO:0007314 | inferred from mutant phenotype morphogenesis of an epithelium ; GO:0002009 | traceable author statement regulation of actin cytoskeleton organization ; GO:0032956 | inferred from mutant phenotype protein localization ; GO:0008104 | traceable author statement rhabdomere development ; GO:0042052 | inferred from mutant phenotype establishment or maintenance of epithelial cell apical/basal polarity ; GO:0045197 | inferred from direct assay positive regulation of cell proliferation ; GO:0008284 | inferred from genetic interaction with conu photoreceptor cell axon guidance ; GO:0072499 | inferred from mutant phenotype regulation of membrane potential in photoreceptor cell ; GO:0016057 | inferred from direct assay actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype" "extrinsic component of membrane ; GO:0019898 | inferred from electronic annotation with InterPro:IPR000798, InterPro:IPR011174, InterPro:IPR011259 cytosol ; GO:0005829 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay cytoplasm ; GO:0005737 | colocalizes_with inferred from direct assay nucleus ; GO:0005634 | colocalizes_with inferred from direct assay adherens junction ; GO:0005912 | inferred from direct assay actin cytoskeleton ; GO:0015629 | colocalizes_with inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | non-traceable author statement spindle ; GO:0005819 | colocalizes_with inferred from direct assay subapical complex ; GO:0035003 | traceable author statement actin filament ; GO:0005884 | colocalizes_with inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay plasma membrane ; GO:0005886 | non-traceable author statement mitotic spindle midzone ; GO:1990023 | inferred from direct assay fusome ; GO:0045169 | NOT inferred from direct assay cleavage furrow ; GO:0032154 | inferred from direct assay apical plasma membrane ; GO:0016324 | inferred from direct assay" "Moe, moe, Dmoe, ERM, CG10701, EMR1, moesin/ezrin/radixin homolog mRNA, l(1)G0415, l(1)G0404, l(1)G0323, l(1)G0067, D17, Emr1, anon-WO03040301.161, anon-WO03040301.159, anon-WO03040301.157, anon-WO03040301.155, dMoe, Moes, gma, moesin, DMoe, Moesin" "IPR000299:FERM domain, IPR000798:Ezrin/radixin/moesin-like, IPR008954:Moesin tail domain, IPR011174:Ezrin/radixin/moesin, IPR011259:Ezrin/radixin/moesin, C-terminal, IPR011993:PH domain-like, IPR014352:FERM/acyl-CoA-binding protein, 3-helical bundle, IPR018979:FERM, N-terminal, IPR018980:FERM, C-terminal PH-like domain, IPR019747:FERM conserved site, IPR019748:FERM central domain, IPR019749:Band 4.1 domain, IPR029071:Ubiquitin-related domain" CG10701 27-Aug-18 DroID_v2018_08 "Drer\ezrb, Drer\nf2b, Drer\zgc:153953, Drer\nf2a, Drer\frmd4bb, Drer\ccdc120, Drer\si:ch211-163l21.4, Drer\msnb, Drer\ezra, Drer\si:ch211-220f12.1, Drer\si:ch211-169p10.1, Drer\msna" - "Cele\erm-1, Cele\nfm-1" "Xtro\ezr, Xtro\rdx, Xtro\msn, Xtro\nf2, Xtro\frmd4a, Xtro\frmd4b" "Mmus\Ezr, Mmus\Msn, Mmus\Ccdc120, Mmus\Nf2, Mmus\5730559C18Rik, Mmus\Rdx, Mmus\Frmd4b, Mmus\Frmd4a" "Hsap\EZR, Hsap\C1orf106, Hsap\NF2, Hsap\RDX, Hsap\FRMD4A, Hsap\FRMD4B, Hsap\CCDC120, Hsap\MSN" pupal stage mesothoracic bristle

"viable,smell perception defective,increased cell death,visible,lethal - all die before end of first instar larval stage,some die during first instar larval stage,partially lethal - majority die,somatic clone,song defective,lethal,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective,developmental rate defective,recessive,size defective,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of P-stage,some die during pharate adult stage,male,female,fertile" "rhabdomere & actin filament, with MoedsRNA.327-775.UAS, hs.PB,rhabdomere & actin filament, with MoedsRNA.327-775.UAS, GMR.PF,photoreceptor cell,wing vein,wing,wing disc,wing hinge,rhabdomere & actin filament, with MoedsRNA.818-1326.UAS, hs.PB,rhabdomere & actin filament, with MoedsRNA.818-1326.UAS, GMR.PF,spindleC587,cyst progenitor cell,wing disc | third instar larval stage,1st posterior cell,wing blade,eye,somatic clone | third instar larval stage,germline cell,wing vein L3,rhabdomere & microvillushs.PB,rhabdomere & plasma membrane | apicalhs.PB,rhabdomere & cytoskeleton | apicalhs.PB,lamina plexus | third instar larval stage,medulla | third instar larval stage,oocyte & cytoskeleton[-],germline cell | embryonic stage,oocyte & cytoskeleton,imaginal disc,medulla,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R8,somatic clone,lamina plexus,embryonic abdominal segment,non-rescuable maternal effect,embryonic/first instar larval cuticle,pole cell,rhabdomere & plasma membrane | apical | somatic clone,rhabdomere & actin filament | somatic clone,basal lamina & dorsal mesothoracic disc & third instar larva,ommatidium,oocyte & actin filament,nurse cell & actin filament,embryonic/larval midgut primordium,embryonic hindgut,presumptive embryonic salivary gland,retina,dorsal trunk primordium,oocyte & actin filament | ectopicnos.UTR.THsimVP16,nurse cell & actin filamentnos.UTR.THsimVP16,nurse cell & actin filamentMoe-PG26,cell non-autonomous | third instar larval stage,cell autonomous | third instar larval stage" FBgn0003093 Pkc98E Protein C kinase 98E http://flybase.org/reports/FBgn0003093 FBgn0005692 protein_coding_gene "protein kinase C activity ; GO:0004697 | inferred from electronic annotation with InterPro:IPR014376 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR000961, InterPro:IPR002290, InterPro:IPR017441, InterPro:IPR017892 protein kinase C activity ; GO:0004697 | inferred from sequence or structural similarity protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000683254" peptidyl-serine phosphorylation ; GO:0018105 | inferred from biological aspect of ancestor with PANTHER:PTN000683254 neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype Golgi organization ; GO:0007030 | inferred from mutant phenotype lipid particle organization ; GO:0034389 | inferred from mutant phenotype long-term memory ; GO:0007616 | inferred from mutant phenotype response to ethanol ; GO:0045471 | inferred from direct assay positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype I-kappaB phosphorylation ; GO:0007252 | inferred from mutant phenotype positive regulation of peptide hormone secretion ; GO:0090277 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity protein phosphorylation ; GO:0006468 | non-traceable author statement dorsal/ventral axis specification ; GO:0009950 | inferred from mutant phenotype negative regulation of cell proliferation ; GO:0008285 | inferred from mutant phenotype intracellular ; GO:0005622 | inferred from biological aspect of ancestor with PANTHER:PTN000683254 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with inaC "PKC-98F, PKC, PKC 98F, CG1954, 98F, dPKC98F, Dpkc3, PKC d98F, nPKC, Pkc3, Nc98F, Pkc98E, PKC98C, PKC98E, PK-C" "IPR000719:Protein kinase domain, IPR000961:AGC-kinase, C-terminal, IPR002219:Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR014376:Protein kinase C, delta/epsilon/eta/theta types, IPR017441:Protein kinase, ATP binding site, IPR017892:Protein kinase, C-terminal, IPR020454:Diacylglycerol/phorbol-ester binding, IPR034669:Novel protein kinase C epsilon, catalytic domain, IPR000008:C2 domain" CG1954 27-Aug-18 DroID_v2018_08 "Drer\pkn1a, Drer\si:ch73-374l24.1, Drer\prkcq, Drer\zgc:153916, Drer\prkcda, Drer\pimr112, Drer\sgk494a, Drer\prkcea, Drer\prkcg, Drer\prkcbb, Drer\pkn3, Drer\si:ch211-14c7.2, Drer\sgk494b, Drer\pkn1b, Drer\prkchb, Drer\prkca, Drer\prkceb, Drer\prkcha, Drer\pkn2" "Scer\DUN1, Scer\PKC1" "Cele\cam-1, Cele\pkc-1, Cele\pkn-1, Cele\tpa-1, Cele\pkc-2" "Xtro\prkcq, Xtro\prkcb, Xtro\pkn3, Xtro\gpha2, Xtro\prkcd, Xtro\prkce, Xtro\prkca, Xtro\tnfrsf1a, Xtro\prkch, Xtro\LOC100493742, Xtro\prkcg, Xtro\pkn1" "Mmus\Prkcq, Mmus\Sprr1b, Mmus\Pkn1, Mmus\Gm5113, Mmus\Pkn2, Mmus\Prkch, Mmus\Prkcd, Mmus\Prkcg, Mmus\Prx, Mmus\Prkca, Mmus\Prkce, Mmus\Prkcb, Mmus\D130040H23Rik, Mmus\Sprr1a, Mmus\Pkn3, Mmus\BC030499" "Hsap\SGK494, Hsap\PRKCD, Hsap\PRKCB, Hsap\PKN3, Hsap\PRKCQ, Hsap\PRKCH, Hsap\PRX, Hsap\PKN1, Hsap\PKN2, Hsap\PRKCE, Hsap\PRKCG, Hsap\PRKCA" " larval stage | second instar , larval stage | third instar , embryonic stage , adult stage , larval stage | first instar , pupal stage " " cell body &&of adult brain

, head

" "chemical resistant,neuroanatomy defective,memory defective,viable" "denticle,ectopic,filzkorper,embryonic head,embryonic/first instar larval cuticle,embryonic/larval central nervous system" FBgn0013733 shot short stop http://flybase.org/reports/FBgn0013733 "FBgn0014183, FBgn0015972, FBgn0020296, FBgn0021837, FBgn0021937, FBgn0022152, FBgn0022170, FBgn0022208, FBgn0022230" protein_coding_gene microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR003108 calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 microtubule binding ; GO:0008017 | traceable author statement actin binding ; GO:0003779 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with kra cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity actin binding ; GO:0003779 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:A1Z6P3 inferred from physical interaction with UniProtKB:Q8T3Y0 "negative regulation of microtubule depolymerization ; GO:0007026 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | traceable author statement lumen formation, open tracheal system ; GO:0035149 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | traceable author statement branch fusion, open tracheal system ; GO:0035147 | inferred from expression pattern muscle attachment ; GO:0016203 | traceable author statement axonogenesis ; GO:0007409 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype microtubule cytoskeleton organization ; GO:0000226 | traceable author statement axonogenesis ; GO:0007409 | traceable author statement mushroom body development ; GO:0016319 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from mutant phenotype apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | traceable author statement branch fusion, open tracheal system ; GO:0035147 | traceable author statement sensory organ development ; GO:0007423 | traceable author statement oocyte fate determination ; GO:0030716 | inferred from mutant phenotype branch fusion, open tracheal system ; GO:0035147 | inferred from mutant phenotype determination of muscle attachment site ; GO:0016204 | traceable author statement actin cytoskeleton organization ; GO:0030036 | traceable author statement axon midline choice point recognition ; GO:0016199 | inferred from mutant phenotype microtubule-based process ; GO:0007017 | non-traceable author statement microtubule cytoskeleton organization ; GO:0000226 | inferred from mutant phenotype positive regulation of filopodium assembly ; GO:0051491 | inferred from mutant phenotype inferred from genetic interaction with kra microtubule-based process ; GO:0007017 | inferred from direct assay microtubule bundle formation ; GO:0001578 | inferred from mutant phenotype regulation of axon extension ; GO:0030516 | inferred from mutant phenotype positive regulation of axon extension ; GO:0045773 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay growth cone ; GO:0030426 | inferred from direct assay adherens junction ; GO:0005912 | traceable author statement cytoskeleton ; GO:0005856 | non-traceable author statement muscle tendon junction ; GO:0005927 | inferred from direct assay fusome ; GO:0045169 | inferred from direct assay microtubule ; GO:0005874 | traceable author statement adherens junction ; GO:0005912 | inferred from direct assay microtubule plus-end ; GO:0035371 | inferred from direct assay astral microtubule ; GO:0000235 | inferred from direct assay axonal growth cone ; GO:0044295 | inferred from direct assay filopodium ; GO:0030175 | inferred from direct assay microtubule ; GO:0005874 | inferred from direct assay "shot, kakp, kak, CG18076, shortstop/kakapo, Shot, grv, l(2)k04204, l(2)k03010, kop, Grv, 42/4, l(2)k10821, l(2)k05821, l(2)k05434, l(2)k15606, l(2)CA4, CG18637, Su(Mir)1" "IPR018159:Spectrin/alpha-actinin, IPR018247:EF-Hand 1, calcium-binding site, IPR001101:Plectin repeat, IPR001589:Actinin-type actin-binding domain, conserved site, IPR001715:Calponin homology domain, IPR002017:Spectrin repeat, IPR002048:EF-hand domain, IPR003108:Gas2-related domain, IPR011992:EF-hand domain pair, IPR001452:SH3 domain" CG18076 27-Aug-18 DroID_v2018_08 "Drer\eppk1, Drer\macf1a, Drer\si:ch211-137a8.2, Drer\syne1b, Drer\evplb, Drer\zgc:100997, Drer\dspa, Drer\syne2b, Drer\wu:fi04e12, Drer\gas2b, Drer\syne1a, Drer\dst, Drer\evpla, Drer\ppl, Drer\pleca, Drer\si:ch211-165e15.1" - Cele\vab-10 "Xtro\plec, Xtro\syne1, Xtro\macf1, Xtro\eppk1, Xtro\dst, Xtro\gas2l2, Xtro\syne2, Xtro\ppl, Xtro\evpl" "Mmus\Smtnl2, Mmus\Dst, Mmus\Clmn, Mmus\Ppl, Mmus\Syne2, Mmus\Macf1, Mmus\Plec, Mmus\Evpl, Mmus\Dsp, Mmus\Syne1, Mmus\Smtnl1" "Hsap\EPPK1, Hsap\PLEC, Hsap\EVPL, Hsap\MACF1, Hsap\SYNE1, Hsap\DSP, Hsap\EVPLL, Hsap\SYNE3, Hsap\PPL, Hsap\SYNE2, Hsap\DST, Hsap\GAS2L1, Hsap\GAS2L2, Hsap\CLMN, Hsap\KIAA0754" " embryonic stage , embryonic stage | stage >=13 , embryonic stage | stage >=11 , embryonic stage | stage 16 " " muscle attachment site

, embryonic peripheral nervous system

, epidermis

, embryonic central nervous system

, organism | segmentally repeated

" " embryonic stage | stage 16 , larval stage | third instar , embryonic stage , embryonic stage | stage >=14 , embryonic stage | stage 12-17 " " embryonic/larval proventriculus

, tendon cell

, scolopidium

, sensory neuron

, muscle attachment site

, epidermis

, chordotonal organ

, neuron

, embryonic/larval pharynx

, intersegmental nerve

" "lethal,recessive,neuroanatomy defective,paralytic,lethal - all die before end of embryonic stage,some die during embryonic stage,decreased cell number,somatic clone,germline clone,visible,lethal - all die before end of larval stage,some die during larval stage" "imaginal disc,chordotonal organ,lateral,scolopidial dendrite,extended germ band embryo,dorsal closure embryo,embryonic epidermis,dendrite & motor neuron | embryonic stage,axon & motor neuron | embryonic stage,neuron,microtubuleMK1),dendrite | dorsal | embryonic stage,presumptive embryonic/larval peripheral nervous system,dorsal,NMJ bouton,supernumerary,supernumerary | third instar larval stage,segmental nerve,RP3 motor neuron,embryonic/larval somatic muscle,embryonic/first instar larval cuticle,muscle attachment site,neuromuscular junction | embryonic stage,embryonic/larval mushroom body,somatic clone,lateral trunk primordium,intersegmental nerve,oocyte,egg chamber & follicle cell | somatic clone,mushroom body & axon,synapse & neuromuscular junction,chordotonal organ & axon | lateral,longitudinal connective,sensory neuron,ovary,germline clone,nurse cell,ectopic,microtubule & ovary | germ-line clone,centrosome & ovary | germ-line clone,axon & pCC neuron,abdominal segmental nerve,embryonic/larval dorsal anastomosis,dorsal trunk primordium,calyx of adult mushroom body,axonMK1),filopodiumMK1),wing,larva,proventriculus inner layer primordium,proventriculus intermediate layer primordium,embryonic proventriculus,embryonic/larval motor neuron,tendon cell,synapse & neuromuscular junctionMK1),RP1 motor neuron,tendon cell & actin filamenthow-24B, sr-md710,tendon cell & microtubulehow-24B, sr-md710" DRSC05459 IE -0.036086644 -3.390270537 -0.954132705 -4.143168369 -1.290758851 -1.384957247 FBgn0003499 sr stripe http://flybase.org/reports/FBgn0003499 "FBgn0010828, FBgn0026215" protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 "ectoderm development ; GO:0007398 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype determination of muscle attachment site ; GO:0016204 | traceable author statement phagocytosis ; GO:0006909 | inferred from mutant phenotype epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype inferred from genetic interaction with bnl pigment metabolic process ; GO:0042440 | traceable author statement muscle organ development ; GO:0007517 | inferred from mutant phenotype central nervous system development ; GO:0007417 | inferred from mutant phenotype somatic muscle development ; GO:0007525 | inferred from mutant phenotype germ-band shortening ; GO:0007390 | inferred from mutant phenotype" - "Sr, l(3)06948, l(3)06948b, l(3)03999, CG7847, sr, SrB, stripe" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR011990:Tetratricopeptide-like helical domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG7847 27-Aug-18 DroID_v2018_08 "Drer\egr2b, Drer\egr4, Drer\osr1, Drer\egr2a, Drer\si:ch211-117k10.3, Drer\osr2, Drer\egr1, Drer\klf15, Drer\klf11a, Drer\sp2, Drer\egr3" "Scer\MIG1, Scer\MSN2, Scer\MIG3, Scer\MSN4, Scer\MIG2, Scer\FZF1" "Cele\odd-1, Cele\odd-2, Cele\egrh-3, Cele\egrh-1" "Xtro\sp2, Xtro\osr2, Xtro\klf15, Xtro\klf11, Xtro\osr1, Xtro\egr2, Xtro\egr3, Xtro\egr1" "Mmus\Sp2, Mmus\Osr1, Mmus\Klf11, Mmus\Egr4, Mmus\Egr1, Mmus\Osr2, Mmus\Egr2, Mmus\Egr3, Mmus\Klf15" "Hsap\SP2, Hsap\EGR4, Hsap\OSR1, Hsap\KLF11, Hsap\KLF15, Hsap\EGR1, Hsap\EGR3, Hsap\EGR2, Hsap\OSR2" " embryonic stage , embryonic stage | stage >=14 , embryonic stage && pupal stage " " muscle attachment site

, epidermis | restricted

" embryonic stage " epidermis | restricted

, muscle attachment site

" "lethal,recessive,viable,visible,flightless,lethal - all die before end of embryonic stage,some die during embryonic stage,cell shape defective,partially lethal - majority die,some die during pupal stage,eye color defective" "thorax,skeletal muscle of abdomen,adult muscle system,dorsal medial muscle,macrochaeta,somatic mesoderm,embryonic/larval dorsal branch,embryonic/larval dorsal trunk,embryonic/larval ganglionic branch,embryonic/larval muscle system,embryonic/larval visceral branch,lch5 cap attachment cell,lch5 ligament attachment cell,muscle fiber,muscle attachment site,embryonic/larval somatic muscle,embryonic/larval tracheal system,adult thorax,mesothoracic tergum & microchaetasr-md710,mesothoracic tergum & chaeta-C253,ventral,lateral transverse muscle | embryonic stage,abdominal 5 ventral longitudinal muscle | embryonic stage,abdominal 6 ventral longitudinal muscle | embryonic stage,abdominal 7 ventral longitudinal muscle | embryonic stage,abdominal 5 lateral transverse muscle | embryonic stage,abdominal 6 lateral transverse muscle | embryonic stage,abdominal 7 lateral transverse muscle | embryonic stage,embryonic somatic muscle,lateral,somatic muscle | embryonic stage,supernumerary,germ band,ectoderm,mesothoracic tergum" FBgn0029891 Pink1 PTEN-induced putative kinase 1 http://flybase.org/reports/FBgn0029891 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719 protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with rho-7 protein binding ; GO:0005515 | inferred from physical interaction with Pgam5 protein kinase activity ; GO:0004672 | inferred from direct assay "mitochondrial fission ; GO:0000266 | inferred from genetic interaction with Drp1 inferred from genetic interaction with Marf inferred from genetic interaction with Opa1 mitochondrion organization ; GO:0007005 | inferred from mutant phenotype inferred from genetic interaction with Buffy mitochondrion transport along microtubule ; GO:0047497 | inferred from mutant phenotype mitochondrion organization ; GO:0007005 | inferred from mutant phenotype negative regulation of programmed cell death ; GO:0043069 | inferred from mutant phenotype establishment of mitochondrion localization ; GO:0051654 | inferred from mutant phenotype negative regulation of mitochondrial fusion ; GO:0010637 | inferred from mutant phenotype regulation of mitochondrial electron transport, NADH to ubiquinone ; GO:1902956 | inferred from genetic interaction with FLYBASE:no biological data available-42; FB:FBgn0019957 positive regulation of compound eye pigmentation ; GO:0048078 | inferred from mutant phenotype negative regulation of neuron apoptotic process ; GO:0043524 | inferred from direct assay protein phosphorylation ; GO:0006468 | inferred from direct assay sperm mitochondrion organization ; GO:0030382 | inferred from mutant phenotype ectopic germ cell programmed cell death ; GO:0035234 | inferred from mutant phenotype regulation of mitochondrion organization ; GO:0010821 | inferred from mutant phenotype mitophagy ; GO:0000422 | inferred from mutant phenotype mitochondrial fission ; GO:0000266 | inferred from genetic interaction with Drp1 inferred from genetic interaction with Opa1 mitochondrion organization ; GO:0007005 | inferred from direct assay positive regulation of mitochondrial fission ; GO:0090141 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype response to oxidative stress ; GO:0006979 | inferred from mutant phenotype intracellular distribution of mitochondria ; GO:0048312 | inferred from mutant phenotype neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay Nebenkern ; GO:0016006 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay "dPINK1, CG4523, BEST:GH23468, Pink1, PINK1, pink1, dPink1, PINK, dPINk1, Pink, :Pink1" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain" CG4523 27-Aug-18 DroID_v2018_08 Drer\pink1 - Cele\pink-1 - Mmus\Pink1 Hsap\PINK1 "visible,neuroanatomy defective,increased cell size,lethal - all die before end of second instar larval stage,some die during second instar larval stage,viable,fertile,progressive,sterile,chemical sensitive,osmotic stress response defective,male sterile,locomotor behavior defective,short lived,increased cell death,flightless,flight defective,heat stress response defective,smell perception defective,neurophysiology defective,recessive,gravitaxis defective,female sterile,partially" "eye,dopamine neuron & adult brainelav.PLu,ommatidium,dopamine neuron & adult brainDdc.PL,interommatidial bristle,pigment cell,photoreceptor & neuronGMR.PF,spermatid,Nebenkern,mitochondrial derivative,dopaminergic neuron,progressive,indirect flight muscle,mitochondrion,mitochondrial crista,mitochondrial crista & indirect flight muscle,minor mitochondrial derivative,wing,depressor muscle,myofibrilda.G32,mitochondrial cristada.G32,mitochondrionMhc.PW,myofibrilMhc.PW,mitochondrial cristaMhc.PW,mitochondrion & dorso-lateral dopaminergic neuronple.PF,adult thorax,mitochondrion & dopaminergic neuron,mitochondrion & indirect flight muscle,mitochondrial inner membrane & indirect flight muscle,mitochondrion & dorso-lateral dopaminergic neuron,dopaminergic PPL1 neuron,dopaminergic PPM1 neuron,dopaminergic PPM2 neuron,neuron,adult somatic muscle,mitochondrial outer membrane,adult antennal lobe,bouton,flight muscle,embryonic/larval neuromuscular junction,synaptic vesicle,spermatozoon,mitochondrial outer membrane & indirect flight muscle,myofibril & indirect flight muscle,dopamine neuron & adult brain,mitochondrion & dopamine neuron & adult brain,thorax,skeletal muscle of thorax,dorso-lateral dopaminergic neuron,Nebenkern derivative,spermatid cyst,eye | adult stage,ommatidium | adult stage" FBgn0039294 Cad96Cb Cadherin 96Cb http://flybase.org/reports/FBgn0039294 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002126, InterPro:IPR015919 calcium ion binding ; GO:0005509 | inferred from sequence model" homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from electronic annotation with InterPro:IPR002126 open tracheal system development ; GO:0007424 | inferred from genetic interaction with shg calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0016339 | inferred from sequence or structural similarity cell-cell adhesion mediated by cadherin ; GO:0044331 | inferred from sequence model plasma membrane ; GO:0005886 | inferred from electronic annotation with InterPro:IPR020894 integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity "DCad96Cb, CG10421, CT29262, CG13664, Cad96Cb, cad96Cb, cad96C, cg13664, Cad96C" "IPR002126:Cadherin, IPR015919:Cadherin-like, IPR020894:Cadherin conserved site" CG13664 27-Aug-18 DroID_v2018_08 "Drer\pcdh2g8, Drer\LOC100006797, Drer\pcdh2g1, Drer\cdh6, Drer\pcdh1a6, Drer\cdhr1a" - Cele\cdh-9 "Xtro\pcdha13, Xtro\pcdh10, Xtro\pcdh9, Xtro\pcdh8, Xtro\cdh7, Xtro\cdh5" "Mmus\Pcdhb22, Mmus\Pcdh8, Mmus\Pcdhb14, Mmus\Pcdh7, Mmus\Pcdhb10, Mmus\Pcdhb17, Mmus\Cdh9, Mmus\Pcdh20, Mmus\Pcdhb9, Mmus\Pcdh19, Mmus\Pcdhb21, Mmus\Pcdhb5, Mmus\Pcdhb4, Mmus\Pcdhb11, Mmus\Pcdhb6, Mmus\Pcdhb3, Mmus\Pcdhb15, Mmus\Pcdhb1, Mmus\Pcdhb2, Mmus\Pcdhb7, Mmus\Gm37013, Mmus\Cdh6, Mmus\Pcdhgc5, Mmus\Pcdh9, Mmus\Cdhr1, Mmus\Pcdh10, Mmus\Pcdhb12, Mmus\Pcdhb8, Mmus\Pcdhb20, Mmus\Pcdhb13, Mmus\Pcdh12, Mmus\Pcdh17, Mmus\Pcdhb18, Mmus\Pcdhb19, Mmus\Pcdh18, Mmus\Pcdhb16" "Hsap\PCDH20, Hsap\PCDHGA4, Hsap\PCDH8, Hsap\PCDHA12, Hsap\PCDHGA1, Hsap\PCDHA3, Hsap\PCDHA11, Hsap\PCDHGC5, Hsap\PCDHA4, Hsap\PCDHB10, Hsap\PCDH18, Hsap\PCDHGA10, Hsap\PCDH15, Hsap\PCDHGA12, Hsap\PCDHAC2, Hsap\PCDHA10, Hsap\PCDHB15, Hsap\PCDHGA2, Hsap\PCDHA2, Hsap\PCDH10, Hsap\PCDH1, Hsap\PCDHA1, Hsap\PCDH19, Hsap\PCDHB11, Hsap\PCDHA5, Hsap\PCDHGB5, Hsap\PCDHB14, Hsap\PCDHGA11, Hsap\PCDH9, Hsap\PCDHA6, Hsap\CDH24, Hsap\CDH6, Hsap\PCDHB3, Hsap\PCDHA7, Hsap\PCDHB1, Hsap\PCDH17, Hsap\PCDHB12, Hsap\PCDHB4, Hsap\PCDHGB6, Hsap\PCDHB5, Hsap\PCDH7, Hsap\PCDHGC4, Hsap\PCDHB6, Hsap\PCDHB8, Hsap\PCDHGB4, Hsap\PCDHA8, Hsap\PCDHGB7, Hsap\PCDHB2, Hsap\PCDHB7, Hsap\PCDH12, Hsap\PCDHGA3, Hsap\PCDHB16, Hsap\PCDHA13, Hsap\PCDHAC1, Hsap\PCDHGA7, Hsap\PCDHGA6, Hsap\CDHR1, Hsap\PCDHGA9, Hsap\PCDHB13, Hsap\PCDHGA5, Hsap\PCDHA9, Hsap\PCDHGB1, Hsap\PCDHGA8, Hsap\PCDHGB2, Hsap\PCDHGC3, Hsap\PCDHB9, Hsap\PCDHGB3" "viable,partially lethal - majority die,some die during pupal stage" FBgn0026479 Drp1 Dynamin related protein 1 http://flybase.org/reports/FBgn0026479 "FBgn0005566, FBgn0005579, FBgn0031438, FBgn0042649" protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR000375, InterPro:IPR001401, InterPro:IPR003130, InterPro:IPR030381 microtubule binding ; GO:0008017 | inferred from biological aspect of ancestor with PANTHER:PTN000170013 GTPase activity ; GO:0003924 | inferred from biological aspect of ancestor with PANTHER:PTN000170013" peroxisome fission ; GO:0016559 | inferred from electronic annotation with InterPro:IPR030556 synaptic vesicle budding from presynaptic endocytic zone membrane ; GO:0016185 | non-traceable author statement positive regulation of mitochondrial fission ; GO:0090141 | inferred from mutant phenotype ventral furrow formation ; GO:0007370 | inferred from mutant phenotype membrane fusion ; GO:0061025 | inferred from biological aspect of ancestor with PANTHER:PTN000170085 mitochondrion organization ; GO:0007005 | inferred from mutant phenotype mitochondrial fission ; GO:0000266 | inferred from mutant phenotype sperm mitochondrion organization ; GO:0030382 | inferred from mutant phenotype mitochondrion localization ; GO:0051646 | inferred from mutant phenotype regulation of mitochondrial fission ; GO:0090140 | inferred from mutant phenotype mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype dynamin family protein polymerization involved in mitochondrial fission ; GO:0003374 | inferred from biological aspect of ancestor with PANTHER:PTN000170085 mitochondrial membrane ; GO:0031966 | inferred from biological aspect of ancestor with PANTHER:PTN000170085 microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity microtubule associated complex ; GO:0005875 | inferred from direct assay "CG3210, Dnm1/Drp1, l(2)22Fc, l(2)ND2, l(2)ND3, l(2)22Fd, Drp1, Drp-1, drp1, Drp, DRP1, drp-1, frat, DRP" "IPR030381:Dynamin-type guanine nucleotide-binding (G) domain, IPR000375:Dynamin central domain, IPR001401:Dynamin, GTPase domain, IPR003130:Dynamin GTPase effector, IPR019762:Dynamin, GTPase region, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR020850:GTPase effector domain, IPR030556:Dynamin-1-like protein, IPR022812:Dynamin superfamily" CG3210 27-Aug-18 DroID_v2018_08 "Drer\mxd, Drer\dnm2a, Drer\si:dkeyp-110c12.3, Drer\mxa, Drer\mxc, Drer\mxe, Drer\dnm1b, Drer\dnm3a, Drer\mxg, Drer\dnm1a, Drer\mxf, Drer\dnm1l, Drer\si:dkey-32e23.4, Drer\mxb" "Scer\MGM1, Scer\VPS1, Scer\DNM1" "Cele\drp-1, Cele\dyn-1" "Xtro\dnm2, Xtro\dnm1, Xtro\dnm1l, Xtro\dnm3" "Mmus\Dnm2, Mmus\Dnm3, Mmus\Dnm1, Mmus\Mx1, Mmus\Dnm1l, Mmus\Mx2" "Hsap\DNM2, Hsap\MX1, Hsap\DNM3, Hsap\MX2, Hsap\DNM1, Hsap\DNM1L" "neurophysiology defective,lethal,recessive,viable,visible" "mitochondrion,Nebenkern,mitochondrionMef2.PR,mitochondrion & primary spermatocyte | germ-line clone,Nebenkern | germline clone,mitochondrial derivative | germline clone,lysosome & larval fat body | somatic clone | cell autonomous,autophagic vacuole & larval fat body | somatic clone | cell autonomous,ventral furrow,mitochondrion & larval salivary gland,mitochondrion & bouton,mitochondrion & larval nervous system,mitochondrion & motor neuron,embryonic/larval neuromuscular junction,trichogen cell" DRSC00574 K 1.078866981 -0.158466985 -0.040794711 -0.18690649 1.710953056 0.227550084 FBgn0033550 CG12341 - http://flybase.org/reports/FBgn0033550 protein_coding_gene - - - "BcDNA:SD17342, CG12341" IPR019334:Transmembrane protein 170 CG12341 27-Aug-18 DroID_v2018_08 "Drer\tmem170a, Drer\tmem170b" Scer\YPR153W Cele\F43G9.13 Xtro\tmem170a "Mmus\Tmem170, Mmus\Tmem170b" "Hsap\TMEM170A, Hsap\TMEM170B" viable FBgn0283521 lola longitudinals lacking http://flybase.org/reports/FBgn0283521 protein_coding_gene "protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 protein binding ; GO:0005515 | inferred from physical interaction with JIL-1 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with ttk" "regulation of imaginal disc-derived wing size ; GO:0044719 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype brain morphogenesis ; GO:0048854 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001135004 gonad development ; GO:0008406 | inferred from mutant phenotype larval somatic muscle development ; GO:0007526 | inferred from expression pattern inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from genetic interaction with SoxN positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from sequence or structural similarity with UniProtKB:Q08605 inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype axon midline choice point recognition ; GO:0016199 | inferred from mutant phenotype inferred from genetic interaction with robo1 inferred from genetic interaction with sli larval lymph gland hemopoiesis ; GO:0035167 | inferred from mutant phenotype locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype R3/R4 cell fate commitment ; GO:0007464 | inferred from mutant phenotype startle response ; GO:0001964 | inferred from mutant phenotype nurse cell apoptotic process ; GO:0045476 | inferred from mutant phenotype axonogenesis ; GO:0007409 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype R7 cell development ; GO:0045467 | inferred from mutant phenotype" nucleoplasm ; GO:0005654 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001135004 "lola, CG12052, eyeful, CG18381, CG18379, CG18378, CG30012, BTB-IV, LD03274, l(2)00642, l(2)s3697, bs06a08.y1, NEST:bs06a08, BcDNA:RH31485, sw59, CG30014, CG30013, CG18380, CG18376, BtbIV, BEST:LD03274, BcDNA:LD17006, Lola, fus7, btb" "IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain, IPR000210:BTB/POZ domain, IPR011333:SKP1/BTB/POZ domain, IPR013087:Zinc finger C2H2-type" CG12052 27-Aug-18 DroID_v2018_08 - "Scer\QDR3, Scer\CYK3" "Cele\sdz-28, Cele\btb-13" - Mmus\Zfp219 Hsap\ZBTB20 " embryonic stage | stage 12-17 , embryonic stage | stage >12 , embryonic stage | stage 1-15 , embryonic stage | stage >=10 , embryonic stage | stage 12-14 , embryonic stage | stage 10,11 , embryonic stage | stage 16-17 " " central nervous system

, histoblast

, organism

, mesoderm

, imaginal disc | presumptive

, embryonic peripheral nervous system

, mesectoderm

, embryonic optic lobe primordium

" " embryonic stage , larval stage | third instar , embryonic stage | stage 1-17 , embryonic stage | stage 1-13 , adult stage " " epithelial cell

, embryonic/larval somatic muscle

, central nervous system

, embryonic peripheral nervous system

, tracheocyte

, organism

, organism

" "neuroanatomy defective,courtship behavior defective,male,somatic clone,lethal,recessive,partially lethal - majority die,viable,fertile,behavior defective,visible,wild-type,partially,heat sensitive,some die during pupal stage,body color defective,size defective" "dorsal multidendritic neuron ddaD,dorsal multidendritic neuron ddaE,dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa,ventral multidendritic neuron vdaB,dendrite & adult antennal lobe projection neuron | somatic cloneGH146,axon & adult antennal lobe projection neuron | somatic cloneGH146,adult antennal lobe projection neuron,somatic clone,adult antennal lobe projection neuron DA1 vPN,adult antennal lobe projection neuron VA1v vPN,adult antennal lobe projection neuron adPN,adult antennal lobe projection neuron lPN,adult antennal lobe projection neuron DL1 adPN,lateral horn,dendrite & adult antennal lobe projection neuron | somatic cloneGH146, lolae76,axon & adult antennal lobe projection neuron | somatic cloneGH146, lolae76,longitudinal connective,intersegmental nerve,A1-7 ventral longitudinal muscle 1,A1-7 ventral longitudinal muscle 2,A1-7 ventral longitudinal muscle 3,A1-7 ventral longitudinal muscle 4,abdominal segmental nerve,commissure,VUM interneuron 1,VUM interneuron 2,VUM interneuron 3,abdominal intersegmental nerve,abdominal 1 lateral monoscolopidial chordotonal organ lch1,abdominal 2 lateral monoscolopidial chordotonal organ lch1,abdominal 3 lateral monoscolopidial chordotonal organ lch1,abdominal 4 lateral monoscolopidial chordotonal organ lch1,abdominal 5 lateral monoscolopidial chordotonal organ lch1,abdominal 6 lateral monoscolopidial chordotonal organ lch1,abdominal 7 lateral monoscolopidial chordotonal organ lch1,abdominal 1 lateral pentascolopidial chordotonal organ lch5,abdominal 2 lateral pentascolopidial chordotonal organ lch5,abdominal 3 lateral pentascolopidial chordotonal organ lch5,abdominal 4 lateral pentascolopidial chordotonal organ lch5,abdominal 5 lateral pentascolopidial chordotonal organ lch5,abdominal 6 lateral pentascolopidial chordotonal organ lch5,abdominal 7 lateral pentascolopidial chordotonal organ lch5,VUM neuron,central nervous system,nurse cell,germline clone,egg chamber,axon & adult antennal lobe projection neuron | somatic clone,dendrite & adult antennal lobe projection neuron | somatic clone,macrochaeta,dorsocentral bristle,scutellar bristle,tormogen cell,gonad,gonadal sheath proper primordium,arista,eye,axon,antennal lobe projection neuron adPN,cell autonomous,antennal lobe projection neuron vPN,antennal lobe projection neuron lPN,dendrite & larval antennal lobe projection neuron | somatic clone | penetrance incomplete | expressivity incomplete | cell autonomous,axon & larval antennal lobe projection neuron | somatic clone | penetrance incomplete | expressivity incomplete | cell autonomous,adult mushroom body,dendrite & adult antennal lobe projection neuron | somatic cloneGH146, lola3.8.UAS,dendrite & adult antennal lobe projection neuron | somatic cloneGH146, lola4.7.UAS,axon & adult antennal lobe projection neuron | somatic cloneGH146, lola4.7.UAS,dendrite & adult antennal lobe projection neuron | somatic cloneGH146, lolaL.UAS,axon & adult antennal lobe projection neuron | somatic cloneGH146, lolaL.UAS,ventral longitudinal muscle,presumptive embryonic/larval central nervous system,dorsal appendage,synapsehow-24B,synapsetwi.PG,dendrite & adult antennal lobe projection neuron | somatic clone | heat sensitiveGH146,axon & adult antennal lobe projection neuron | somatic clone | heat sensitiveGH146,heat sensitive,embryonic/larval neuroblast,trichogen cell,mesothoracic tergum,ganglion mother cell,wing,posterior" DRSC27862 IEK 0.725057073 -1.799942145 5.589401193 -1.538656754 1.43490837 1.608543358 FBgn0085106 l(3)S068808 l(3)S068808 http://flybase.org/reports/FBgn0085106 gene - - - l(3)S068808 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0061134 l(3)S001901 lethal (3) S001901 http://flybase.org/reports/FBgn0061134 gene - - - "0019/01, l(3)S001901" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0069234 gl(2L)159-23 gl(2L)159-23 http://flybase.org/reports/FBgn0069234 gene molecular_function ; GO:0003674 | no biological data available morphogenesis of embryonic epithelium ; GO:0016331 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available gl(2L)159-23 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,germline clone,non-rescuable maternal effect,recessive" FBgn0264651 loose-caboose loose caboose http://flybase.org/reports/FBgn0264651 gene - trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype - loose-caboose - - 27-Aug-18 DroID_v2018_08 - - - - - - "embryonic/larval dorsal branch 10,embryonic/larval tracheal system,eye,somatic clone" FBgn0039379 CG5886 - http://flybase.org/reports/FBgn0039379 protein_coding_gene syntaxin binding ; GO:0019905 | inferred from electronic annotation with InterPro:IPR026183 - - CG5886 IPR026183:Taxilin family CG5886 27-Aug-18 DroID_v2018_08 "Drer\txlnba, Drer\slmapb, Drer\txlna, Drer\txlng, Drer\txlnbb" - Cele\T22C1.6 "Xtro\txlna, Xtro\txlng" "Mmus\Txlng, Mmus\Txlnb, Mmus\Txlna" "Hsap\TXLNB, Hsap\PPFIBP1, Hsap\TXLNA, Hsap\TXLNG" viable FBgn0023520 CG3857 - http://flybase.org/reports/FBgn0023520 - protein_coding_gene - "gravitaxis ; GO:0042332 | inferred from mutant phenotype nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ; GO:0000184 | inferred from sequence or structural similarity with UniProtKB:Q9H0W8" intracellular ; GO:0005622 | inferred from sequence or structural similarity with UniProtKB:Q9H0W8 "EG:39E1.3, CG3857" IPR027417:P-loop containing nucleoside triphosphate hydrolase CG3857 27-Aug-18 DroID_v2018_08 Drer\smg9 - Cele\smg-9 Xtro\smg9 Mmus\Smg9 Hsap\SMG9 "gravitaxis defective,viable,lethal" FBgn0051439 Muc96D Mucin 96D http://flybase.org/reports/FBgn0051439 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 extracellular matrix structural constituent ; GO:0005201 | inferred from sequence model chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 extracellular matrix ; GO:0031012 | inferred from sequence model "CG31439, Muc96D" IPR002557:Chitin binding domain CG31439 27-Aug-18 DroID_v2018_08 - Scer\FLO5 - - - - "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0265758 lncRNA:CR44565 - http://flybase.org/reports/FBgn0265758 non_protein_coding_gene - - - "CR44565, lincRNA.590" - CR44565 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035954 Doc3 Dorsocross3 http://flybase.org/reports/FBgn0035954 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR001699, InterPro:IPR002070, InterPro:IPR008967, InterPro:IPR018186" anterior Malpighian tubule development ; GO:0061327 | inferred from mutant phenotype cardiocyte differentiation ; GO:0035051 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "Dm-DOC3, CG5093, Doc3, doc3, Doc" "IPR001699:Transcription factor, T-box, IPR002070:Transcription factor, Brachyury, IPR008967:p53-like transcription factor, DNA-binding, IPR018186:Transcription factor, T-box, conserved site" CG5093 27-Aug-18 DroID_v2018_08 "Drer\tbx6, Drer\tbx3b, Drer\tbx5b, Drer\tbx6l, Drer\tbx5a, Drer\tbx3a, Drer\tbx22, Drer\tbx20, Drer\tbx16, Drer\tbx18, Drer\tbr1b, Drer\mgaa, Drer\eomesa, Drer\tbx21, Drer\tbx2b, Drer\tbr1a, Drer\eomesb, Drer\ta, Drer\tbx4, Drer\tbx2a, Drer\tb, Drer\tbx19, Drer\tbx1" - "Cele\tbx-42, Cele\mls-1, Cele\tbx-11, Cele\tbx-2, Cele\mab-9, Cele\tbx-30" "Xtro\t2, Xtro\eomes, Xtro\tbx1, Xtro\tbx20, Xtro\tbx22, Xtro\tbx4, Xtro\tbx5, Xtro\mga, Xtro\t, Xtro\vegt, Xtro\tbx2, Xtro\tbr1, Xtro\tbx18, Xtro\tbx6, Xtro\tbx3" "Mmus\Tbx18, Mmus\Tbx2, Mmus\Tbx4, Mmus\Tbx22, Mmus\Eomes, Mmus\Tbx3, Mmus\Tbx19, Mmus\Tbr1, Mmus\Mga, Mmus\Tbx1, Mmus\Tbx6, Mmus\Tbx20, Mmus\Tbx15, Mmus\Tbx5, Mmus\T, Mmus\Tbx10, Mmus\Tbx21" "Hsap\TBX10, Hsap\TBX3, Hsap\EOMES, Hsap\MGA, Hsap\TBR1, Hsap\TBX21, Hsap\TBX22, Hsap\TBX4, Hsap\TBX20, Hsap\TBX18, Hsap\T, Hsap\TBX5, Hsap\TBX6, Hsap\TBX2, Hsap\TBX15, Hsap\TBX19, Hsap\TBX1" embryonic stage--pupal stage " embryonic stage , embryonic stage | stage 15-16 , embryonic stage | stage 5-15 , embryonic stage | stage 9-16 , embryonic stage | stage 5-11 " " mesoderm | restricted

, embryonic anterior Malpighian tubule

, abdominal lateral pentascolopidial chordotonal organ lch5

, amnioserosa

, parasegment && ectoderm && mesoderm

, cardioblast | subset

, dorsal pouch

, organism | dorso-lateral

, procephalic neurogenic region

" "viable,chemical resistant" FBgn0063373 snoRNA:snR38:54Ec snoRNA:snR38:54Ec http://flybase.org/reports/FBgn0063373 snoRNA_gene - - - "Snr38snoRNA, CR32901, snoRNA:snR38:54Ec" - CR32901 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060621 l(3)S088501b lethal (3) S088501b http://flybase.org/reports/FBgn0060621 gene - - - "0885/01, l(3)S088501b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0038181 CG9297 - http://flybase.org/reports/FBgn0038181 protein_coding_gene - - - "CG9297, Dmel\CG9297" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR022812:Dynamin superfamily, IPR031692:EH domain-containing protein, N-terminal" CG9297 27-Aug-18 DroID_v2018_08 "Drer\ehd1b, Drer\ehd3, Drer\srl, Drer\wu:fb80c09, Drer\ehd1a, Drer\chia.5, Drer\ehd2b, Drer\ovgp1, Drer\chia.1, Drer\ehd2a, Drer\ehd4" Scer\EDE1 "Cele\cht-1, Cele\cht-4, Cele\cht-2" "Xtro\ehd4, Xtro\chia, Xtro\ehd3, Xtro\srl, Xtro\ehd2, Xtro\ehd1, Xtro\chit1, Xtro\LOC548945" "Mmus\Ovgp1, Mmus\Chil6, Mmus\Ehd2, Mmus\Chil3, Mmus\Chil5, Mmus\Chia1, Mmus\Ehd3, Mmus\Ehd1, Mmus\Ehd4, Mmus\Srl, Mmus\Chil1, Mmus\Hmgn5, Mmus\Chit1" "Hsap\CHI3L2, Hsap\HMGN5, Hsap\CHIT1, Hsap\EHD1, Hsap\CHIA, Hsap\OVGP1, Hsap\EHD2, Hsap\EHD4, Hsap\CHI3L1, Hsap\SRL, Hsap\EHD3" "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum DRSC16469 E 1.132200079 0.799375909 4.004378938 -1.050881108 -0.225437855 0.043052098 FBgn0263262 spa3 - http://flybase.org/reports/FBgn0263262 gene - gonad development ; GO:0008406 | inferred from mutant phenotype digestive tract mesoderm development ; GO:0007502 | inferred from mutant phenotype - spa3 - - 27-Aug-18 DroID_v2018_08 - - - - - - "gonad,gonadal sheath proper primordium,visceral mesoderm" FBgn0070020 BG01020 BG01020 http://flybase.org/reports/FBgn0070020 gene - - - BG01020 - - 27-Aug-18 DroID_v2018_08 - - - - - - stress response defective FBgn0261581 CG42691 - http://flybase.org/reports/FBgn0261581 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42691 - CG42691 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060809 l(3)S054908 lethal (3) S054908 http://flybase.org/reports/FBgn0060809 gene - - - "0549/08, l(3)S054908" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0051032 CR31032 - http://flybase.org/reports/FBgn0051032 pseudogene_attribute - - - "CG31032, BcDNA:GH15189, CR31032" - CR31032 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036614 Golgin104 Golgin 104 http://flybase.org/reports/FBgn0036614 protein_coding_gene Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab2 signal transducer activity ; GO:0004871 | non-traceable author statement - trans-Golgi network ; GO:0005802 | inferred from direct assay "CG4925, golgin-104, Golgin104" - CG4925 27-Aug-18 DroID_v2018_08 Drer\ccdc186 - "Cele\arrd-16, Cele\cccp-1" Xtro\ccdc186 Mmus\Ccdc186 "Hsap\SRRM5, Hsap\CCDC186" FBgn0011768 Fdh Formaldehyde dehydrogenase http://flybase.org/reports/FBgn0011768 FBgn0002986 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR002328, InterPro:IPR014183 octanol dehydrogenase activity ; GO:0004552 | inferred from direct assay S-(hydroxymethyl)glutathione dehydrogenase activity ; GO:0051903 | inferred from direct assay alcohol dehydrogenase (NAD) activity ; GO:0004022 | inferred from direct assay S-nitrosoglutathione reductase activity ; GO:0080007 | inferred from mutant phenotype" ethanol oxidation ; GO:0006069 | inferred from electronic annotation with InterPro:IPR014183 regulation of peptidyl-cysteine S-nitrosylation ; GO:2000169 | inferred from mutant phenotype regulation of nitric oxide metabolic process ; GO:0080164 | inferred by curator from GO:0080007 visual learning ; GO:0008542 | inferred from mutant phenotype alcohol metabolic process ; GO:0006066 | inferred by curator from GO:0004022 - "Fdh, ODH, Odh, CG6598, gfd/odh, ADHX, odh, gfd, GSNOR, ADHX_DROME, fdh" "IPR002328:Alcohol dehydrogenase, zinc-type, conserved site, IPR011032:GroES-like, IPR013149:Alcohol dehydrogenase, C-terminal, IPR013154:Alcohol dehydrogenase, N-terminal, IPR014183:Alcohol dehydrogenase class III, IPR016040:NAD(P)-binding domain" CG6598 27-Aug-18 DroID_v2018_08 "Drer\adh8a, Drer\zgc:77938, Drer\zgc:63568, Drer\adh5, Drer\adh8b" "Scer\SFA1, Scer\ADH5" Cele\H24K24.3 "Xtro\adh5, Xtro\adh1a, Xtro\adh1b, Xtro\adh7, Xtro\adh1c, Xtro\adh1" "Mmus\Adh1, Mmus\Adh7, Mmus\Adh6b, Mmus\Adh4, Mmus\Adh6a, Mmus\Adh5" "Hsap\ADH1C, Hsap\ADH1A, Hsap\ADH7, Hsap\ADH4, Hsap\ADH1B, Hsap\ADH5, Hsap\ADH6" larval stage--adult stage "memory defective,heat sensitive,electrophoretic variant,viable,fertile" FBgn0019909 afl autosomal female lethal http://flybase.org/reports/FBgn0019909 - gene - - - afl - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,heat sensitive" FBgn0030004 CG10958 - http://flybase.org/reports/FBgn0030004 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG10958 "IPR029440:Dynein regulatory complex protein 1, C-terminal" CG10958 27-Aug-18 DroID_v2018_08 Drer\drc1 Scer\VIK1 - Xtro\drc1 Mmus\Drc1 Hsap\DRC1 viable FBgn0060746 l(3)S065312b lethal (3) S065312b http://flybase.org/reports/FBgn0060746 gene - - - "0653/12, l(3)S065312b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0037831 Cap-H2 Chromosome associated protein H2 http://flybase.org/reports/FBgn0037831 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with MRG15 chromatin binding ; GO:0003682 | inferred from direct assay "chromosome condensation ; GO:0030261 | inferred from electronic annotation with InterPro:IPR031739 chromosome separation ; GO:0051304 | inferred from mutant phenotype inferred from genetic interaction with glu, MRG15 inferred from genetic interaction with Cap-D3 chromosome organization ; GO:0051276 | inferred from mutant phenotype chromatin organization ; GO:0006325 | inferred from mutant phenotype inferred from genetic interaction with MRG15 male meiosis chromosome segregation ; GO:0007060 | inferred from mutant phenotype" condensin complex ; GO:0000796 | inferred from sequence or structural similarity with HGNC:25071 "CG14685, Cap-H2, CAP-H2, CapH2, dCap-H2, cap-H2" "IPR031737:Condensin-2 complex subunit H2, C-terminal, IPR031739:Condensin-2 complex subunit H2" CG14685 27-Aug-18 DroID_v2018_08 Drer\ncaph2 - Cele\kle-2 Xtro\ncaph2 Mmus\Ncaph2 Hsap\NCAPH2 "viable,fertile,meiotic cell cycle defective,male semi-fertile,male sterile" "spermatozoon,polytene chromosome & nurse cell,polytene chromosome & nurse cellExel6159),primary spermatocyte in meiotic prophase I,primary spermatocyte in meiotic anaphase I,polytene chromosome & larval salivary gland43B,polytene chromosome & larval salivary gland | conditional - heat sensitivehs.PB,polytene chromosome & larval salivary glandhs.PB,polytene chromosomehs.PU,embryonic/larval salivary gland | third instar larval stage,nuclear envelopehs.PU" FBgn0260741 CG3281 - http://flybase.org/reports/FBgn0260741 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 positive regulation of JAK-STAT cascade ; GO:0046427 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 "CG3281, anon-WO0140519.243, 87A7-9/1, anon-87Aa" "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type" CG3281 27-Aug-18 DroID_v2018_08 "Drer\znf131, Drer\zbtb18, Drer\si:ch211-79k12.2, Drer\zbtb14, Drer\patz1, Drer\si:dkeyp-121d2.7, Drer\bcl6ab, Drer\zbtb7a, Drer\si:ch211-119o8.6, Drer\zbtb24, Drer\zbtb17, Drer\e4f1, Drer\zbtb49" "Scer\AZF1, Scer\ZAP1" "Cele\C04F5.9, Cele\F56D1.1, Cele\Y55F3AM.14, Cele\row-1, Cele\blmp-1" "Xtro\zbtb11, Xtro\zbtb41, Xtro\znf238.2, Xtro\zbtb40, Xtro\zbtb14, Xtro\zbtb26, Xtro\hic1, Xtro\gzf1, Xtro\zbtb7c" "Mmus\Zbtb7a, Mmus\Zbtb42, Mmus\Zbtb7c, Mmus\Zbtb24, Mmus\Zbtb17, Mmus\Zbtb6, Mmus\Mynn, Mmus\Zbtb26, Mmus\Patz1, Mmus\Zfp599, Mmus\Zbtb48, Mmus\Zbtb14, Mmus\Zfp60, Mmus\Bcl6b, Mmus\Vezf1, Mmus\Zfp131, Mmus\Zbtb18, Mmus\Zbtb41, Mmus\Zbtb38, Mmus\Zbtb7b, Mmus\Gzf1" "Hsap\GZF1, Hsap\ZBTB17, Hsap\ZBTB7A, Hsap\PRDM5, Hsap\ZBTB6, Hsap\MYNN, Hsap\ZNF616, Hsap\ZBTB26, Hsap\ZNF131, Hsap\BCL6B, Hsap\ZBTB11, Hsap\ZBTB24, Hsap\ZNF415, Hsap\ZBTB48, Hsap\ZBTB7B, Hsap\ZBTB41, Hsap\PATZ1, Hsap\ZSCAN21, Hsap\ZNF208, Hsap\ZBTB14, Hsap\ZBTB7C, Hsap\ZBTB18" FBgn0030484 GstT4 Glutathione S transferase T4 http://flybase.org/reports/FBgn0030484 protein_coding_gene - biological_process ; GO:0008150 | no biological data available cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with RGD:70952 "GST-theta, CG1681, GstT4, gstt4, GSTT4, DmGSTT4" "IPR004045:Glutathione S-transferase, N-terminal, IPR004046:Glutathione S-transferase, C-terminal, IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold" CG1681 27-Aug-18 DroID_v2018_08 "Drer\gstt1b, Drer\gstt2, Drer\eef1g, Drer\vars, Drer\mars, Drer\gstr, Drer\gstt1a, Drer\eef1e1" "Scer\CAM1, Scer\GTT2, Scer\TEF4, Scer\GTT1, Scer\YGR201C, Scer\URE2" "Cele\gst-37, Cele\gst-32, Cele\gst-34" "Xtro\eef1g, Xtro\gstt1, Xtro\eef1e1" "Mmus\Eef1e1, Mmus\Gstt4, Mmus\Gstt1, Mmus\Gstt2, Mmus\Eef1g, Mmus\Gstt3, Mmus\Vars, Mmus\Mars" "Hsap\GSTT2, Hsap\MARS, Hsap\GSTT2B, Hsap\EEF1E1, Hsap\EEF1G, Hsap\GSTT1, Hsap\VARS" "viable,fertile" FBgn0005130 l(1)X2 lethal (1) X2 http://flybase.org/reports/FBgn0005130 - gene - - - l(1)X2 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" "embryonic head,embryonic segment,mitotic cell cycle | gastrula stage" FBgn0065319 l(2)SH1919 lethal (2) SH1919 http://flybase.org/reports/FBgn0065319 gene - - - "l(2)SH1919, l(2)SH2 1919, SH1919" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0024262 acd(2)5M7 auditory courtship defective 5M7 http://flybase.org/reports/FBgn0024262 - gene molecular_function ; GO:0003674 | no biological data available auditory behavior ; GO:0031223 | inferred from mutant phenotype male courtship behavior ; GO:0008049 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available acd(2)5M7 - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,auditory perception defective" FBgn0275434 asRNA:CR46266 - http://flybase.org/reports/FBgn0275434 non_protein_coding_gene - - - CR46266 - CR46266 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032341 Reps RALBP1 associated Eps domain containing http://flybase.org/reports/FBgn0032341 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 protein binding ; GO:0005515 | inferred from physical interaction with Rlip - - "REPS, Reps, CG6192" "IPR000261:EH domain, IPR011992:EF-hand domain pair, IPR002048:EF-hand domain" CG6192 27-Aug-18 DroID_v2018_08 "Drer\reps2, Drer\reps1" "Scer\END3, Scer\TAX4, Scer\SLA1, Scer\IRS4, Scer\PAN1, Scer\EDE1" Cele\reps-1 "Xtro\reps2, Xtro\eps15, Xtro\reps1, Xtro\eps15l1" "Mmus\Reps2, Mmus\Eps15l1, Mmus\Reps1" "Hsap\REPS2, Hsap\EPS15, Hsap\REPS1" viable FBgn0051760 CG31760 - http://flybase.org/reports/FBgn0051760 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from electronic annotation with InterPro:IPR017978 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from biological aspect of ancestor with PANTHER:PTN002091395 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR017978 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN002091395 "CG17215, CG17214, BcDNA:RE52162, CG31760" "IPR017978:GPCR family 3, C-terminal" CG31760 27-Aug-18 DroID_v2018_08 "Drer\gpr158b, Drer\si:ch211-156l18.8, Drer\gpr158a" - Cele\F39B2.8 "Xtro\plgrkt, Xtro\gpr158" "Mmus\Gpr179, Mmus\Gpr158" "Hsap\GPR179, Hsap\GPR158" "viable,fertile" DRSC02590 K 0.711210242 -0.529050037 -1.223619393 -0.093090562 -0.324758179 2.060973629 FBgn0034985 CG3328 - http://flybase.org/reports/FBgn0034985 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR024061 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR008967" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR008967" - CG3328 "IPR008967:p53-like transcription factor, DNA-binding, IPR030392:Intramolecular chaperone auto-processing domain, IPR024061:NDT80 DNA-binding domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR026932:Myelin gene regulatory factor C-terminal domain 1" CG3328 27-Aug-18 DroID_v2018_08 Drer\myrf - "Cele\myrf-1, Cele\myrf-2" Xtro\myrf "Mmus\Myrf, Mmus\Myrfl" "Hsap\MYRFL, Hsap\MYRF" "viable,fertile" FBgn0044401 Scim26 Sensitized chromosome inheritance modifier 26 http://flybase.org/reports/FBgn0044401 gene - female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype - Scim26 - - 27-Aug-18 DroID_v2018_08 - - - - - - "meiotic cell cycle defective,dominant" FBgn0266200 lncRNA:CR44895 - http://flybase.org/reports/FBgn0266200 non_protein_coding_gene - - - CR44895 - CR44895 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000406 Cyt-b5-r Cytochrome b5-related http://flybase.org/reports/FBgn0000406 - protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR012171 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR018506 "lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR005804, InterPro:IPR012171" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR012171 lipid particle ; GO:0005811 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay "Cyt-b5, Cyt-b, TU-36B, Cytb, TU36B, Cytb5, CG13279, Cyt-b5-r, Cytb5r" "IPR018506:Cytochrome b5, heme-binding site, IPR001199:Cytochrome b5-like heme/steroid binding domain, IPR005804:Fatty acid desaturase domain, IPR012171:Fatty acid desaturase" CG13279 27-Aug-18 DroID_v2018_08 "Drer\dpm3, Drer\fads2, Drer\cyb5a" - "Cele\fbxa-76, Cele\F58B4.2, Cele\C24H12.1, Cele\fat-4, Cele\T27A1.3, Cele\F49E11.8, Cele\fat-3" "Xtro\dpm3, Xtro\fads2" "Mmus\Fads2, Mmus\Dpm3, Mmus\Fads3, Mmus\Fads1, Mmus\4833423E24Rik" "Hsap\DPM3, Hsap\FADS3, Hsap\FADS1, Hsap\FADS2" " embryonic stage | stage 16 , pupal stage | late , larval stage&&adult stage " " larval visceral muscle

, tergosternal muscle

, skeletal muscle of leg

, embryonic/larval somatic muscle

" viable FBgn0003535 stop stopped http://flybase.org/reports/FBgn0003535 - gene - oogenesis ; GO:0048477 | inferred from mutant phenotype - stop - - 27-Aug-18 DroID_v2018_08 - - - - - - female sterile FBgn0034381 List Lithium-inducible SLC6 transporter http://flybase.org/reports/FBgn0034381 protein_coding_gene neurotransmitter:sodium symporter activity ; GO:0005328 | inferred from electronic annotation with InterPro:IPR000175 transporter activity ; GO:0005215 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 cation:amino acid symporter activity ; GO:0005416 | inferred from sequence model neurotransmitter transporter activity ; GO:0005326 | inferred from sequence or structural similarity with DAT transport ; GO:0006810 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 neurotransmitter transport ; GO:0006836 | inferred from sequence or structural similarity with DAT response to lithium ion ; GO:0010226 | inferred from mutant phenotype amino acid transmembrane import ; GO:0044745 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 integral component of membrane ; GO:0016021 | inferred from sequence model "List, CG15088, DmNAT2" IPR000175:Sodium:neurotransmitter symporter CG15088 27-Aug-18 DroID_v2018_08 "Drer\zgc:158225, Drer\slc6a19a.1, Drer\slc6a11a, Drer\slc6a14, Drer\si:ch211-132b12.6, Drer\slc6a15, Drer\slc6a16a, Drer\slc6a19b, Drer\si:ch211-132b12.2, Drer\slc6a4a, Drer\slc6a2, Drer\slc6a8, Drer\si:ch211-132b12.1, Drer\zgc:174946, Drer\slc6a5, Drer\slc6a6a, Drer\si:ch211-132b12.3, Drer\slc6a18, Drer\slc6a13l, Drer\slc6a17, Drer\slc6a13, Drer\slc6a1l, Drer\slc6a6b, Drer\slc6a1a, Drer\slc6a13, Drer\slc6a4b, Drer\slc6a9, Drer\slc6a1b, Drer\slc6a16b, Drer\si:ch211-117c9.5" - "Cele\snf-9, Cele\mod-5, Cele\snf-5, Cele\snf-3, Cele\dat-1, Cele\snf-7, Cele\snf-12, Cele\snf-11, Cele\snf-6, Cele\snf-2" "Xtro\slc6a13, Xtro\slc6a8, Xtro\slc6a7, Xtro\slc6a17, Xtro\slc6a9, Xtro\slc6a19, Xtro\slc6a6, Xtro\slc6a16, Xtro\slc6a3, Xtro\slc6a15, Xtro\slc6a1, Xtro\slc6a2, Xtro\LOC100127682, Xtro\slc6a4, Xtro\slc6a14.2, Xtro\slc6a12, Xtro\slc6a5" "Mmus\Slc6a18, Mmus\Slc6a5, Mmus\Slc6a13, Mmus\Slc6a20a, Mmus\Slc6a17, Mmus\Slc6a7, Mmus\Slc6a1, Mmus\Slc6a11, Mmus\Slc6a19, Mmus\Slc6a20b, Mmus\Slc6a15, Mmus\Slc6a4, Mmus\Slc6a3, Mmus\Slc6a9, Mmus\Slc6a14, Mmus\Slc6a8, Mmus\Slc6a6, Mmus\Slc6a2, Mmus\Slc6a12" "Hsap\SLC6A17, Hsap\SLC6A18, Hsap\SLC6A20, Hsap\SLC6A19, Hsap\SLC6A2, Hsap\SLC6A7, Hsap\SLC6A14, Hsap\SLC6A13, Hsap\SLC6A9, Hsap\SLC6A11, Hsap\SLC6A3, Hsap\SLC6A15, Hsap\SLC6A5, Hsap\SLC6A4, Hsap\SLC6A12, Hsap\SLC6A8, Hsap\SLC6A1, Hsap\SLC6A6" "chemical sensitive,partially lethal - majority die,some die during pupal stage" FBgn0052826 tRNA:Pro-CGG-1-1 transfer RNA:Proline-CGG 1-1 http://flybase.org/reports/FBgn0052826 tRNA_gene CCG codon-amino acid adaptor activity ; GO:0033424 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033424 cytosol ; GO:0005829 | inferred by curator from GO:0033424 "AE002611.trna1-ProCGG, tRNA:P:CGG:AE002611, CR32826, chrX.trna15-ProCGG, tRNA-Pro-CGG-1-1, tRNA:Pro-CGG-1-1, tRNA:CR32826, CCG" - CR32826 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030605 ND-B18 NADH dehydrogenase (ubiquinone) B18 subunit http://flybase.org/reports/FBgn0030605 protein_coding_gene NADH dehydrogenase (ubiquinone) activity ; GO:0008137 | inferred from electronic annotation with InterPro:IPR008698 NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:P17568 "mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with UniProtKB:P17568" mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:P17568 "NB8M, ND-B18, CG5548" "IPR008698:NADH:ubiquinone oxidoreductase, B18 subunit" CG5548 27-Aug-18 DroID_v2018_08 Drer\ndufb7 - Cele\D2030.4 Xtro\ndufb7 Mmus\Ndufb7 Hsap\NDUFB7 "visible,lethal - all die before end of pupal stage,some die during pupal stage" trichogen cell FBgn0267899 CR46187 - http://flybase.org/reports/FBgn0267899 pseudogene_attribute - - - "CR46187, CG12717-related" - CR46187 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037255 Fip1 Factor interacting with poly(A) polymerase 1 http://flybase.org/reports/FBgn0037255 protein_coding_gene myosin binding ; GO:0017022 | inferred from physical interaction with Myo10A RNA binding ; GO:0003723 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000336935 pre-mRNA cleavage required for polyadenylation ; GO:0098789 | inferred from biological aspect of ancestor with PANTHER:PTN000336935 positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with Ras85D mRNA 3'-end processing by stem-loop binding and cleavage ; GO:0006398 | inferred from mutant phenotype mRNA polyadenylation ; GO:0006378 | inferred from biological aspect of ancestor with PANTHER:PTN000336935 positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from genetic interaction with Ras85D nucleus ; GO:0005634 | inferred from direct assay mRNA cleavage and polyadenylation specificity factor complex ; GO:0005847 | inferred from biological aspect of ancestor with PANTHER:PTN000336935 "clone 1.35, anon-EST:Liang-1.35, Fip1, CG1078, dFip1, FIP1" "IPR002713:FF domain, IPR007854:Pre-mRNA polyadenylation factor Fip1" CG1078 27-Aug-18 DroID_v2018_08 "Drer\fip1l1a, Drer\fip1l1b" Scer\FIP1 Cele\fipp-1 Xtro\fip1l1 Mmus\Fip1l1 Hsap\FIP1L1 "lethal,viable" embryonic/larval brain DRSC12147 K 0.024469664 0.893397531 -0.60381522 -0.264861956 -2.183820967 -0.282578402 FBgn0036311 CG17666 - http://flybase.org/reports/FBgn0036311 protein_coding_gene - - - "bs31g10.y1, CG17666" - CG17666 27-Aug-18 DroID_v2018_08 - - "Cele\C04G6.7, Cele\C27A2.5, Cele\F29D10.2, Cele\T01B7.8, Cele\C04G6.10" - - - viable FBgn0003078 Ppb Photophobe http://flybase.org/reports/FBgn0003078 - gene - - - "Phb, Ppb" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265994 lncRNA:CR44769 - http://flybase.org/reports/FBgn0265994 non_protein_coding_gene - - - "CR44769, lincRNA.187" - CR44769 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0261611 CG42700 - http://flybase.org/reports/FBgn0261611 protein_coding_gene - - - "CG42700, CG13165, CG34233, ORE-16" IPR015943:WD40/YVTN repeat-like-containing domain CG42700 27-Aug-18 DroID_v2018_08 - - "Cele\H10D18.5, Cele\C01C4.2" - - - FBgn0061162 l(1)6C-166 lethal (1) 6C-166 http://flybase.org/reports/FBgn0061162 gene - - - "6C-166, l(1)6C-166" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0262811 CG43182 - http://flybase.org/reports/FBgn0262811 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43182 - CG43182 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0003584 su(t) suppressor of tan http://flybase.org/reports/FBgn0003584 - gene - - - su(t) - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260274 GSd486 - http://flybase.org/reports/FBgn0260274 gene - - - GSd486 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve,segmental nerve" FBgn0038131 CG15888 - http://flybase.org/reports/FBgn0038131 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15888 - CG15888 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0261723 Dbx Dbx http://flybase.org/reports/FBgn0261723 protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR017970 axon guidance ; GO:0007411 | inferred from mutant phenotype neuron fate commitment ; GO:0048663 | inferred from mutant phenotype" - "Dbx, CG12361, dbx, dDbx, CG42234, CG13925" "IPR017970:Homeobox, conserved site, IPR009057:Homeobox domain-like, IPR001356:Homeobox domain, IPR000047:Helix-turn-helix motif" CG42234 27-Aug-18 DroID_v2018_08 "Drer\dbx1b, Drer\lbx2, Drer\barx2, Drer\tlx2, Drer\lbx1a, Drer\barhl2, Drer\nkx1.2lb, Drer\vox, Drer\tlx1, Drer\dbx2, Drer\ved, Drer\dbx1a, Drer\hlx1, Drer\LOC100008066, Drer\tlx3b, Drer\barx1, Drer\barhl1b, Drer\si:dkey-43p13.5, Drer\nkx6.1, Drer\pnx, Drer\lbx1b" - "Cele\ceh-51, Cele\egl-5" "Xtro\nkx1-1, Xtro\nkx6-3, Xtro\nkx6-2, Xtro\barhl2, Xtro\tlx3, Xtro\tlx1, Xtro\ventx1.2, Xtro\nkx1-2, Xtro\barhl1, Xtro\dbx1, Xtro\barx1, Xtro\tlx2, Xtro\hlx" "Mmus\Lbx2, Mmus\Barhl2, Mmus\Nkx6-2, Mmus\Tlx1, Mmus\Dbx2, Mmus\Nkx1-2, Mmus\Tlx2, Mmus\Barx1, Mmus\Sebox, Mmus\Barx2, Mmus\Nkx1-1, Mmus\Hlx, Mmus\Barhl1, Mmus\Tlx3, Mmus\Nkx6-3, Mmus\Dbx1, Mmus\Lbx1" "Hsap\BARHL2, Hsap\HLX, Hsap\BARX1, Hsap\LEUTX, Hsap\NKX1-1, Hsap\TLX2, Hsap\LBX2, Hsap\TLX1, Hsap\DBX2, Hsap\TLX3, Hsap\NKX6-3, Hsap\DBX1, Hsap\LBX1, Hsap\BARHL1, Hsap\BARX2" DRSC08271 K -0.30386415 0.964323143 -0.33257532 0.319406664 2.870977665 0.982165077 FBgn0262073 JC11 - http://flybase.org/reports/FBgn0262073 gene - response to anesthetic ; GO:0072347 | inferred from mutant phenotype - JC11 - - 27-Aug-18 DroID_v2018_08 - - - - - - "chemical sensitive,recessive" FBgn0003289 Rst(3)amd alpha methyl dopa-resistant on 3 http://flybase.org/reports/FBgn0003289 FBgn0004948 gene - - - "Amdr, Rst(3)amd" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,chemical resistant,dominant" FBgn0067044 U14 U14 http://flybase.org/reports/FBgn0067044 gene - - - U14 - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,eye color defective,lethal" "chaeta,pigment cell" FBgn0032860 CG15130 - http://flybase.org/reports/FBgn0032860 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "38C.48, CG15130" IPR032006:Transmembrane inner ear expressed protein CG15130 27-Aug-18 DroID_v2018_08 Drer\tmie - Cele\Y39A1C.1 - Mmus\Tmie Hsap\TMIE viable FBgn0266784 lncRNA:CR45249 - http://flybase.org/reports/FBgn0266784 non_protein_coding_gene - - - CR45249 - CR45249 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001420 l(1)6Dd lethal (1) 6Dd http://flybase.org/reports/FBgn0001420 - gene - - - l(1)6Dd - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0003074 Pgi Phosphoglucose isomerase http://flybase.org/reports/FBgn0003074 - protein_coding_gene glucose-6-phosphate isomerase activity ; GO:0004347 | inferred from mutant phenotype "gluconeogenesis ; GO:0006094 | inferred from electronic annotation with InterPro:IPR001672, InterPro:IPR018189 glycolytic process ; GO:0006096 | inferred from electronic annotation with InterPro:IPR001672, InterPro:IPR018189, InterPro:IPR023096" lipid particle ; GO:0005811 | inferred from direct assay "CG8251, GPI, pgi, Gpi, PGI, Pgi, gpi" "IPR018189:Phosphoglucose isomerase, conserved site, IPR001672:Phosphoglucose isomerase (PGI), IPR023096:Phosphoglucose isomerase, C-terminal" CG8251 27-Aug-18 DroID_v2018_08 "Drer\gpib, Drer\gpia" Scer\PGI1 Cele\gpi-1 Xtro\gpi Mmus\Gpi1 Hsap\GPI "electrophoretic variant,slow,viable,fertile,lethal,recessive" FBgn0003482 spn-D spindle D http://flybase.org/reports/FBgn0003482 "FBgn0047153, FBgn0051069" protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR020588 DNA-dependent ATPase activity ; GO:0008094 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 single-stranded DNA binding ; GO:0003697 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 endodeoxyribonuclease activity ; GO:0004520 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001415033 four-way junction DNA binding ; GO:0000400 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 double-stranded DNA binding ; GO:0003690 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 recombinase activity ; GO:0000150 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 oocyte fate determination ; GO:0030716 | inferred from mutant phenotype strand invasion ; GO:0042148 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 intracellular mRNA localization ; GO:0008298 | traceable author statement response to ionizing radiation ; GO:0010212 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 reciprocal meiotic recombination ; GO:0007131 | inferred from mutant phenotype polarity specification of dorsal/ventral axis ; GO:0009951 | inferred from mutant phenotype microtubule organizing center organization ; GO:0031023 | inferred from mutant phenotype mitotic recombination ; GO:0006312 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 oogenesis ; GO:0048477 | traceable author statement oogenesis ; GO:0048477 | inferred from genetic interaction with fs(1)K10 meiotic DNA recombinase assembly ; GO:0000707 | inferred from biological aspect of ancestor with PANTHER:PTN001118198 oocyte localization involved in germarium-derived egg chamber formation ; GO:0030720 | inferred from mutant phenotype intracellular mRNA localization ; GO:0008298 | inferred from mutant phenotype germarium-derived oocyte fate determination ; GO:0007294 | inferred from genetic interaction with mus301 dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype polarity specification of anterior/posterior axis ; GO:0009949 | inferred from mutant phenotype reciprocal meiotic recombination ; GO:0007131 | traceable author statement karyosome formation ; GO:0030717 | inferred from mutant phenotype Rad51B-Rad51C-Rad51D-XRCC2 complex ; GO:0033063 | inferred from biological aspect of ancestor with PANTHER:PTN001118198 replication fork ; GO:0005657 | inferred from biological aspect of ancestor with PANTHER:PTN001118198 "spn-D, Spn-D, spnD, spndD, CG31069, BcDNA:RE19845, rad51C" "IPR013632:DNA recombination and repair protein Rad51-like, C-terminal, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR020588:DNA recombination and repair protein RecA-like, ATP-binding domain" CG31069 27-Aug-18 DroID_v2018_08 "Drer\rad51c, Drer\xrcc3" "Scer\DMC1, Scer\RAD51, Scer\RAD55, Scer\RAD57" Cele\rad-51 "Xtro\rad51c, Xtro\xrcc3" "Mmus\Rad51b, Mmus\Xrcc3, Mmus\Rad51c" "Hsap\RAD51C, Hsap\RAD51B, Hsap\XRCC3" adult stage | female ovary

"viable,fertile,lethal" "chorion | maternal effect,karyosome,egg,dorsal,dorsal appendage,oocyte,nurse cell,synaptonemal complex,germline cyst,microtubule organizing center & oocyte,presumptive oocyte" FBgn0025393 CG14795 - http://flybase.org/reports/FBgn0025393 - protein_coding_gene - - - "EG:196F3.3, CG14795" - CG14795 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0005232 l(3)R26 lethal of Roberts 26 http://flybase.org/reports/FBgn0005232 - gene - - - "l(3)26, l(3)R26" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,polyphasic,recessive" FBgn0037280 CG1126 - http://flybase.org/reports/FBgn0037280 protein_coding_gene phosphatidylinositol-3-phosphate binding ; GO:0032266 | inferred from sequence or structural similarity with HGNC:970 phosphatidylinositol-3-phosphate binding ; GO:0032266 | inferred from biological aspect of ancestor with PANTHER:PTN000482504 cilium assembly ; GO:0060271 | inferred from sequence or structural similarity with HGNC:970 intracellular transport ; GO:0046907 | inferred from biological aspect of ancestor with PANTHER:PTN000482504 cilium assembly ; GO:0060271 | inferred from sequence model inferred from expression pattern BBSome ; GO:0034464 | inferred from biological aspect of ancestor with PANTHER:PTN000482504 BBSome ; GO:0034464 | inferred from sequence or structural similarity with HGNC:970 ciliary basal body ; GO:0036064 | inferred from biological aspect of ancestor with PANTHER:PTN000482504 "CG1126, BBS5" "IPR006606:Bardet-Biedl syndrome 5 protein, IPR014003:DM16 repeat, IPR030804:Bardet-Biedl syndrome 5 protein/sex-determination protein fem-3, IPR011993:PH domain-like" CG1126 27-Aug-18 DroID_v2018_08 "Drer\klhl41a, Drer\klhl40a, Drer\bbs5, Drer\klhl41b, Drer\klhl40b" - "Cele\bbs-5, Cele\pafo-1" "Xtro\paf1, Xtro\klhl40, Xtro\bbs5, Xtro\klhl41" "Mmus\Bbs5, Mmus\Klhl41, Mmus\Paf1, Mmus\Klhl40" "Hsap\KLHL40, Hsap\PAF1, Hsap\KLHL41, Hsap\BBS5" viable DRSC12168 E 0.649027914 0.578822865 -1.670328423 0.470314141 0.340752514 0.129257066 FBgn0029184 E(Khc)ek2 E(Khc)ek2 http://flybase.org/reports/FBgn0029184 gene - - - E(Khc)ek2 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030443 CG12715 - http://flybase.org/reports/FBgn0030443 protein_coding_gene - - - CG12715 IPR008166:Glycosyltransferase family 92 CG12715 27-Aug-18 DroID_v2018_08 "Drer\si:zfos-464b6.2, Drer\si:dkey-56i24.1, Drer\si:ch73-211l2.1, Drer\zgc:194839" - "Cele\ZK1025.4, Cele\C14C6.6, Cele\galt-1, Cele\C49A1.5, Cele\C18G1.7, Cele\Y47D3B.4, Cele\F36F12.3, Cele\C14C6.8, Cele\F13G3.3, Cele\ZK488.6, Cele\C31B8.7, Cele\F49C12.5, Cele\K06H6.4, Cele\C01G5.9, Cele\F28H7.7, Cele\ZK488.5, Cele\F46F5.7" "Xtro\LOC100492375, Xtro\LOC100145503, Xtro\LOC100495879" - - viable FBgn0032848 nesd nessun dorma http://flybase.org/reports/FBgn0032848 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from physical interaction with CHEBI:59521 female germline ring canal stabilization ; GO:0008335 | inferred from mutant phenotype male meiosis cytokinesis ; GO:0007112 | inferred from mutant phenotype midbody ; GO:0030496 | inferred from direct assay male germline ring canal ; GO:0035323 | inferred from direct assay fusome ; GO:0045169 | inferred from direct assay intercellular bridge ; GO:0045171 | inferred from direct assay female germline ring canal ; GO:0035324 | inferred from direct assay "38B.16, CG10722, nesd" "IPR011050:Pectin lyase fold/virulence factor, IPR012334:Pectin lyase fold" CG10722 27-Aug-18 DroID_v2018_08 Drer\shcbp1 - - Xtro\shcbp1 "Mmus\Shcbp1l, Mmus\Shcbp1" "Hsap\SHCBP1, Hsap\SHCBP1L" "viable,fertile,male semi-sterile,meiotic cell cycle defective,partially lethal - majority die" "onion stage spermatid,Nebenkern,contractile ring,cleavage furrow,spermatocyte ring canal,nurse cell ring canal,nurse cell" FBgn0065114 mfs(1)6E male-female-sterile in region 6E http://flybase.org/reports/FBgn0065114 gene - "regulation of female receptivity, post-mating ; GO:0046008 | inferred from mutant phenotype sperm storage ; GO:0046693 | inferred from mutant phenotype" - mfs(1)6E - - 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,recessive,female sterile" "male accessory gland,male accessory gland main cell" FBgn0035028 Start1 Start1 http://flybase.org/reports/FBgn0035028 protein_coding_gene cholesterol binding ; GO:0015485 | inferred from biological aspect of ancestor with PANTHER:PTN000253260 - - "CG3522, Start, Start1, start1, StART1" "IPR000799:Steroidogenic acute regulatory protein-like, IPR002913:START domain, IPR023393:START-like domain, IPR019498:MENTAL domain" CG3522 27-Aug-18 DroID_v2018_08 "Drer\star, Drer\LOC100331467, Drer\stard3, Drer\stard3nl, Drer\stard5" - "Cele\strl-1, Cele\tag-340" "Xtro\star, Xtro\stard3, Xtro\stard3nl" "Mmus\Stard5, Mmus\Stard3, Mmus\Stard3nl, Mmus\Star, Mmus\Stard6, Mmus\Acot12" "Hsap\STARD6, Hsap\STARD5, Hsap\STARD3, Hsap\STARD3NL, Hsap\STAR" viable FBgn0265918 lncRNA:CR44707 - http://flybase.org/reports/FBgn0265918 non_protein_coding_gene - - - "lincRNA.1015, CR44707" - CR44707 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0046678 anon-38C.15 anon-38C.15 http://flybase.org/reports/FBgn0046678 gene - - - "38C.15, anon-38C.15" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263656 CG43647 - http://flybase.org/reports/FBgn0263656 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43647, mlncRNA42E5-1, lincRNA.258" - CG43647 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0058005 CR40005 - http://flybase.org/reports/FBgn0058005 pseudogene_attribute - - - "CG40005, CR40005" - CR40005 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0028856 CG18063 - http://flybase.org/reports/FBgn0028856 protein_coding_gene myosin light chain binding ; GO:0032027 | inferred from reviewed computational analysis - - "DS07486.5, BG:DS07486.5, CG18063" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR000048:IQ motif, EF-hand binding site" CG18063 27-Aug-18 DroID_v2018_08 Drer\spata17 - - - Mmus\Spata17 Hsap\SPATA17 viable FBgn0040546 CG14705 - http://flybase.org/reports/FBgn0040546 protein_coding_gene - - - CG14705 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001415 l(1)3Ee lethal (1) 3Ee http://flybase.org/reports/FBgn0001415 - gene - - - "l(1)RC245, l(1)3Ee" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0067729 l(3)J1 lethal (3) J1 http://flybase.org/reports/FBgn0067729 gene - - - l(3)J1 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0083008 snoRNA:Psi28S-1135e snoRNA:Psi28S-1135e http://flybase.org/reports/FBgn0083008 snoRNA_gene - - - "snoRNA:Psi28S-1135e, Psi28S-1135e, psi28S-1135e, CR34601, chrX:16979721..16979820" - CR34601 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0050058 CG30058 - http://flybase.org/reports/FBgn0050058 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG30058 - CG30058 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051230 CG31230 - http://flybase.org/reports/FBgn0051230 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG31230 - CG31230 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible" mesothoracic tergum FBgn0259183 CG42287 - http://flybase.org/reports/FBgn0259183 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG13353, CG42287" - CG42287 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036330 CG11263 - http://flybase.org/reports/FBgn0036330 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with UniProtKB:H9IUR0 3'-5' exonuclease activity ; GO:0008408 | NOT inferred from sequence or structural similarity with UniProtKB:H9IUR0 protein homodimerization activity ; GO:0042803 | inferred from sequence or structural similarity with UniProtKB:H9IUR0 - P granule ; GO:0043186 | inferred from sequence or structural similarity with UniProtKB:H9IUR0 CG11263 IPR012337:Ribonuclease H-like domain CG11263 27-Aug-18 DroID_v2018_08 Drer\exd1 - Cele\egal-1 Xtro\exd1 Mmus\Exd1 Hsap\EXD1 "partially lethal - majority die,some die during pupal stage" FBgn0060534 l(3)S100513 lethal (3) S100513 http://flybase.org/reports/FBgn0060534 gene - - - "1005/13, l(3)S100513" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0017427 anon-68Ea anon-68Ea http://flybase.org/reports/FBgn0017427 - gene - - - "T1, anon-68Ea" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0025157 ms(2)A10 ms(2)A10 http://flybase.org/reports/FBgn0025157 - gene - - - ms(2)A10 - - 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,recessive" FBgn0262712 ifm(2)RS5 - http://flybase.org/reports/FBgn0262712 gene - flight ; GO:0060361 | inferred from mutant phenotype adult somatic muscle development ; GO:0007527 | inferred from mutant phenotype - ifm(2)RS5 - - 27-Aug-18 DroID_v2018_08 - - - - - - "flightless,recessive" dorsal medial muscle FBgn0050212 tRNA:Arg-CCT-1-2 transfer RNA:Arginine-CCT 1-2 http://flybase.org/reports/FBgn0050212 tRNA_gene AGG codon-amino acid adaptor activity ; GO:0033448 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033448 cytosol ; GO:0005829 | inferred by curator from GO:0033448 "AE002787.trna2-ArgCCT, tRNA:R:CCT:AE002787-a, CR30133, CR30212, chr2R.trna60-ArgCCT, tRNA-Arg-CCT-1-2, tRNA:Arg-CCT-1-2, tRNA:CR30212, AGG" - CR30212 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031126 Cyp6v1 Cyp6v1 http://flybase.org/reports/FBgn0031126 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN001209891" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "6v1, CG1829, Cyp6v1" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG1829 27-Aug-18 DroID_v2018_08 "Drer\tbxas1, Drer\cyp3c2, Drer\cyp3a65, Drer\cyp3c3, Drer\cyp3c1, Drer\cyp3c4" Scer\ERG11 "Cele\cyp-13A1, Cele\cyp-13A12, Cele\cyp-43A1, Cele\cyp-13A4, Cele\cyp-44A1, Cele\cyp-13A7, Cele\cyp-25A2, Cele\cyp-13A8, Cele\cyp-13A10, Cele\cyp-13A2, Cele\cyp-25A1, Cele\cyp-13B2, Cele\cyp-13A5, Cele\cyp-25A6, Cele\cyp-13A3, Cele\cyp-13A11, Cele\cyp-25A3, Cele\cyp-13A6, Cele\cyp-13B1, Cele\cyp-25A4" "Xtro\tbxas1, Xtro\LOC100494419, Xtro\cyp3a4, Xtro\cyp3a5" "Mmus\Cyp3a59, Mmus\Cyp3a41a, Mmus\Cyp3a41b, Mmus\Tbxas1, Mmus\Cyp3a25, Mmus\Cyp3a44, Mmus\Cyp3a57, Mmus\Cyp3a16, Mmus\Cyp3a13, Mmus\Cyp3a11" "Hsap\CYP3A5, Hsap\CYP3A7, Hsap\TBXAS1, Hsap\CYP3A7-CYP3A51P, Hsap\CYP3A4, Hsap\CYP3A43" "viable,fertile" FBgn0005272 l(3)SG92 lethal (3) SG92 http://flybase.org/reports/FBgn0005272 - gene - - - l(3)SG92 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0000225 Bsb Blunt short bristle http://flybase.org/reports/FBgn0000225 - gene molecular_function ; GO:0003674 | no biological data available antennal morphogenesis ; GO:0048800 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available Bsb - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,dominant,lethal,recessive,viable,fertile" "macrochaeta,arista,arista lateral,actin filament & arista,microtubule & arista" FBgn0015922 cln clown http://flybase.org/reports/FBgn0015922 - gene - compound eye cone cell differentiation ; GO:0042675 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from genetic interaction with aos - cln - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,eye color defective,recessive,visible,fertile,female fertile,male fertile" "eye,ommatidium,pigment cell,secondary pigment cell,ectopic,tertiary pigment cell,cone cell,eye disc & photoreceptor cell,photoreceptor cell,lens,dorsal compartment" FBgn0029864 CG15894 - http://flybase.org/reports/FBgn0029864 protein_coding_gene - - - CG15894 - CG15894 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" FBgn0040705 ND-B8 NADH dehydrogenase (ubiquinone) B8 subunit http://flybase.org/reports/FBgn0040705 protein_coding_gene NADH dehydrogenase (ubiquinone) activity ; GO:0008137 | inferred from biological aspect of ancestor with PANTHER:PTN000306062 NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:O43678 "mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with UniProtKB:O43678" mitochondrial respiratory chain complex I ; GO:0005747 | inferred from biological aspect of ancestor with PANTHER:PTN000306062 mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:O43678 "CG15434, NI8M, ND-B8" "IPR007741:Ribosomal protein/NADH dehydrogenase domain, IPR016464:NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 2, IPR012336:Thioredoxin-like fold" CG15434 27-Aug-18 DroID_v2018_08 Drer\ndufa2 Scer\MRPL51 Cele\Y63D3A.7 "Xtro\ndufa2, Xtro\LOC100495196" Mmus\Ndufa2 Hsap\NDUFA2 "viable,visible,planar polarity defective" mesothoracic tergum FBgn0264698 lncRNA:CR43967 - http://flybase.org/reports/FBgn0264698 non_protein_coding_gene - - - CR43967 - CR43967 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0013910 Dtf-1 Dtf-1 http://flybase.org/reports/FBgn0013910 - gene - - - "DTF-1, Dtf-1" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0025160 l(2)GA339 lethal (2) GA339 http://flybase.org/reports/FBgn0025160 - gene - - - "GA339, l(2)GA339" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" ganglion mother cell GMC4-2a FBgn0262105 lncRNA:CR42858 - http://flybase.org/reports/FBgn0262105 non_protein_coding_gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype regulation of gene expression ; GO:0010468 | inferred from mutant phenotype - CR42858 - CR42858 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0053483 CG33483 - http://flybase.org/reports/FBgn0053483 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33483 IPR010512:Protein of unknown function DUF1091 CG33483 27-Aug-18 DroID_v2018_08 - - Cele\K12H4.7 - - - FBgn0260366 GSd234 - http://flybase.org/reports/FBgn0260366 gene - - - GSd234 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0011659 Mlh1 Mlh1 http://flybase.org/reports/FBgn0011659 - protein_coding_gene "mismatched DNA binding ; GO:0030983 | inferred from electronic annotation with InterPro:IPR002099, InterPro:IPR013507 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002099, InterPro:IPR013507 ATPase activity ; GO:0016887 | inferred from biological aspect of ancestor with PANTHER:PTN000008161 single-stranded DNA binding ; GO:0003697 | inferred from biological aspect of ancestor with PANTHER:PTN000008161" mismatch repair ; GO:0006298 | inferred from biological aspect of ancestor with PANTHER:PTN000008161 MutLalpha complex ; GO:0032389 | inferred from biological aspect of ancestor with PANTHER:PTN000008164 synaptonemal complex ; GO:0000795 | inferred from biological aspect of ancestor with PANTHER:PTN000008164 chiasma ; GO:0005712 | inferred from biological aspect of ancestor with PANTHER:PTN000008164 "dmlh1, dmlh-1, CG11482, Mlh1" "IPR002099:DNA mismatch repair protein family, IPR003594:Histidine kinase-like ATPase, C-terminal domain, IPR013507:DNA mismatch repair protein, C-terminal, IPR014721:Ribosomal protein S5 domain 2-type fold, subgroup, IPR014762:DNA mismatch repair, conserved site, IPR020568:Ribosomal protein S5 domain 2-type fold, IPR032189:DNA mismatch repair protein Mlh1, C-terminal" CG11482 27-Aug-18 DroID_v2018_08 Drer\mlh1 Scer\MLH1 Cele\mlh-1 Xtro\mlh1 Mmus\Mlh1 Hsap\MLH1 viable FBgn0063485 Lasp Lasp http://flybase.org/reports/FBgn0063485 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781 protein binding ; GO:0005515 | inferred from physical interaction with Actn actin binding ; GO:0003779 | inferred from direct assay regulation of myofibril size ; GO:0014881 | inferred from mutant phenotype muscle thin filament assembly ; GO:0071689 | inferred from mutant phenotype pole cell formation ; GO:0007279 | inferred from mutant phenotype positive regulation of pole plasm oskar mRNA localization ; GO:0045856 | inferred from mutant phenotype sperm individualization ; GO:0007291 | inferred from mutant phenotype sarcomere organization ; GO:0045214 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype sperm individualization complex ; GO:0070864 | inferred from direct assay focal adhesion ; GO:0005925 | inferred from direct assay Z disc ; GO:0030018 | inferred from direct assay A band ; GO:0031672 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "CG3849, cDNA B, anon-73Bd, Lasp, lasp" "IPR000900:Nebulin repeat, IPR001452:SH3 domain, IPR001781:Zinc finger, LIM-type" CG3849 27-Aug-18 DroID_v2018_08 "Drer\neb, Drer\nrap, Drer\lasp1, Drer\nebl, Drer\dbnlb" "Scer\ABP1, Scer\BOI1" "Cele\F42H10.3, Cele\dbn-1" "Xtro\nebl, Xtro\neb, Xtro\lasp1" "Mmus\Dbnl, Mmus\Nrap, Mmus\Lasp1, Mmus\Nebl, Mmus\Neb" "Hsap\LASP1, Hsap\NEB, Hsap\NEBL, Hsap\NRAP, Hsap\DBNL" "partially lethal - majority die,hatching behavior defective,decreased cell number,grandchildless,lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,visible,viable,male sterile,female fertile,reduced" "pole cell,ectopic,hub cell,trichogen cell,mesothoracic tergum,investment cone,individualization stage spermatid" DRSC10379 EK -0.43576585 0.184164187 -0.940571665 1.503371166 2.30026385 0.235878809 FBgn0001529 l(1)11Ee lethal (1) 11Ee http://flybase.org/reports/FBgn0001529 - gene - - - l(1)11Ee - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0016669 Hrp75 Hrp75 http://flybase.org/reports/FBgn0016669 - gene single-stranded DNA binding ; GO:0003697 | inferred from direct assay biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "hrp75, Hrp75" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031968 CG7231 - http://flybase.org/reports/FBgn0031968 protein_coding_gene - - - CG7231 IPR019356:Protein of unknown function DUF2181 CG7231 27-Aug-18 DroID_v2018_08 "Drer\fam151a, Drer\fam151b" - Cele\mnr-1 "Xtro\fam151a, Xtro\fam151b" "Mmus\Fam151b, Mmus\Fam151a" "Hsap\FAM151B, Hsap\FAM151A" "lethal,recessive,viable,fertile" FBgn0039616 CG11828 - http://flybase.org/reports/FBgn0039616 protein_coding_gene "procollagen-proline 4-dioxygenase activity ; GO:0004656 | inferred from electronic annotation with InterPro:IPR013547 L-ascorbic acid binding ; GO:0031418 | inferred from electronic annotation with InterPro:IPR006620 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen ; GO:0016702 | inferred from electronic annotation with InterPro:IPR013547 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR006620" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006620, InterPro:IPR013547 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern" endoplasmic reticulum ; GO:0005783 | inferred from electronic annotation with InterPro:IPR013547 CG11828 "IPR013547:Prolyl 4-hydroxylase alpha-subunit, N-terminal, IPR006620:Prolyl 4-hydroxylase, alpha subunit, IPR011990:Tetratricopeptide-like helical domain" CG11828 27-Aug-18 DroID_v2018_08 "Drer\p4ha1b, Drer\p4ha3, Drer\p4ha1a, Drer\p4ha2, Drer\zgc:152670, Drer\zgc:158254, Drer\p4htm" - "Cele\Y43F8B.19, Cele\phy-3, Cele\phy-4, Cele\C14E2.4, Cele\phy-2" "Xtro\p4ha1, Xtro\p4ha2, Xtro\p4ha3" "Mmus\P4htm, Mmus\P4ha2, Mmus\P4ha3, Mmus\P4ha1" "Hsap\P4HA2, Hsap\P4HTM, Hsap\P4HA3, Hsap\P4HA1" viable FBgn0041184 Socs36E Suppressor of cytokine signaling at 36E http://flybase.org/reports/FBgn0041184 protein_coding_gene protein kinase inhibitor activity ; GO:0004860 | inferred from biological aspect of ancestor with PANTHER:PTN000043893 positive regulation of proteasomal ubiquitin-dependent protein catabolic process ; GO:0032436 | inferred from electronic annotation with InterPro:IPR028420 haltere development ; GO:0007482 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype notum morphogenesis ; GO:0048802 | inferred from mutant phenotype regulation of JAK-STAT cascade ; GO:0046425 | traceable author statement germ-line stem cell population maintenance ; GO:0030718 | inferred from mutant phenotype negative regulation of sevenless signaling pathway ; GO:0045873 | inferred from genetic interaction with sev negative regulation of protein kinase activity ; GO:0006469 | inferred from biological aspect of ancestor with PANTHER:PTN000043893 cytokine-mediated signaling pathway ; GO:0019221 | inferred from biological aspect of ancestor with PANTHER:PTN000043893 long-term memory ; GO:0007616 | inferred from mutant phenotype negative regulation of JAK-STAT cascade ; GO:0046426 | inferred from genetic interaction with Stat92E negative regulation of R7 cell differentiation ; GO:0045677 | inferred from genetic interaction with sev negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from mutant phenotype negative regulation of JAK-STAT cascade ; GO:0046426 | inferred from mutant phenotype imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype cell dedifferentiation ; GO:0043697 | inferred from genetic interaction with bam compound eye pigmentation ; GO:0048072 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000043893 "CG15154, SOCS36E, socs36E, dmSocs36E, SOCS, socs60E1, Socs, dSOCS, clone 2.2, anon-EST:Liang-2.2, Socs36E, SocS36E, socs36e" "IPR000980:SH2 domain, IPR001496:SOCS box domain, IPR028420:Suppressor of cytokine signalling 5" CG15154 27-Aug-18 DroID_v2018_08 "Drer\socs4, Drer\cishb, Drer\socs7, Drer\socs3a, Drer\socs6b, Drer\socs6, Drer\socs1a, Drer\socs1b, Drer\socs5a, Drer\socs5b, Drer\socs9, Drer\socs2, Drer\cish, Drer\socs3b" - - "Xtro\socs3, Xtro\socs3, Xtro\socs4, Xtro\socs2, Xtro\socs6, Xtro\cish, Xtro\socs5, Xtro\socs1" "Mmus\Socs4, Mmus\Socs7, Mmus\Socs3, Mmus\Socs6, Mmus\Cish, Mmus\Socs1, Mmus\Socs5, Mmus\Socs2" "Hsap\SOCS7, Hsap\CISH, Hsap\SOCS1, Hsap\SOCS6, Hsap\SOCS5, Hsap\SOCS3, Hsap\SOCS2, Hsap\SOCS4" "visible,viable,fertile,male semi-sterile,lethal - all die before end of P-stage,partially,some die during pharate adult stage,short lived,memory defective,RU486 conditional" "anterior crossvein,wing vein,ectopic,eye,photoreceptor cell R7,supernumerary,cyst progenitor cell,male,male germline stem cell,somatic clone,border follicle cell,humerus,haltere,pigment cell,wing,germline cell" DRSC02455 IEK 0.507591113 -2.900628656 -1.232231707 2.41611484 -0.768366818 2.089294204 FBgn0034787 CG13535 - http://flybase.org/reports/FBgn0034787 protein_coding_gene - - - CG13535 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036433 CG9628 - http://flybase.org/reports/FBgn0036433 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG9628 - CG9628 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" FBgn0264656 paltry paltry http://flybase.org/reports/FBgn0264656 gene - "trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - paltry - - 27-Aug-18 DroID_v2018_08 - - - - - - "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0029715 CG11444 - http://flybase.org/reports/FBgn0029715 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:14634 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG11444 "IPR019380:Casein kinase substrate, phosphoprotein PP28" CG11444 27-Aug-18 DroID_v2018_08 "Drer\pdap1b, Drer\pdap1a" - - Xtro\pdap1 Mmus\Pdap1 Hsap\PDAP1 viable FBgn0041707 7B2 7B2 http://flybase.org/reports/FBgn0041707 protein_coding_gene peptidase activator activity ; GO:0016504 | inferred from direct assay neuropeptide signaling pathway ; GO:0007218 | inferred from electronic annotation with InterPro:IPR007945 positive regulation of peptidase activity ; GO:0010952 | inferred from direct assay positive regulation of proteolysis ; GO:0045862 | inferred from direct assay secretory granule ; GO:0030141 | inferred from electronic annotation with InterPro:IPR007945 "d7B2, CG1168, FBgn0040073, 7B2" IPR007945:Neuroendocrine 7B2 precursor CG1168 27-Aug-18 DroID_v2018_08 "Drer\scg5, Drer\scg5" - Cele\sbt-1 Xtro\scg5 Mmus\Scg5 Hsap\SCG5 viable FBgn0044496 DTD45.10 DTD45.10 http://flybase.org/reports/FBgn0044496 gene - - - DTD45.10 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0020418 I-element\RTase I element reverse transcriptase http://flybase.org/reports/FBgn0020418 FBgn0013982 transposable_element_gene "RNA-DNA hybrid ribonuclease activity ; GO:0004523 | inferred from electronic annotation with InterPro:IPR002156 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR002156, InterPro:IPR012337" - - "ORF2, I\T, I-element\RTase, I-Factor ORF2, ORF2p" "IPR000477:Reverse transcriptase domain, IPR005135:Endonuclease/exonuclease/phosphatase, IPR012337:Ribonuclease H-like domain, IPR002156:Ribonuclease H domain" - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265064 lncRNA:CR44175 - http://flybase.org/reports/FBgn0265064 non_protein_coding_gene - - - "CR44175, lincRNA.812" - CR44175 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0052123 tRNA:CR32123:Psi transfer RNA:CR32123 pseudogene http://flybase.org/reports/FBgn0052123 pseudogene_attribute - - - "AE002602.trna21-LeuAAG, tRNA:L:AAG:AE002602, tRNA:CR32123:Psi, CR32123" - CR32123 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0028635 ifm(2)RU7 indirect flight muscle (2) RU7 http://flybase.org/reports/FBgn0028635 gene molecular_function ; GO:0003674 | no biological data available muscle organ development ; GO:0007517 | inferred from mutant phenotype polytene chromosome puff ; GO:0005703 | inferred from direct assay ifm(2)RU7 - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive,flight defective,sterile,viable" "wing,dorsal medial muscle,indirect flight muscle & myofibril" FBgn0001385 l(1)2Bq lethal (1) 2Bq http://flybase.org/reports/FBgn0001385 - gene - - - l(1)2Bq - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0267305 lncRNA:CR45741 - http://flybase.org/reports/FBgn0267305 non_protein_coding_gene - - - CR45741 - CR45741 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259110 mmd mind-meld http://flybase.org/reports/FBgn0259110 protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR001590, InterPro:IPR002870, InterPro:IPR006586" membrane protein ectodomain proteolysis ; GO:0006509 | inferred from sequence or structural similarity with HGNC:195 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with HGNC:195 "mmd, CG42252, CG15603, CG15604, CT26192, CG9163" "IPR018358:Disintegrin, conserved site, IPR000742:EGF-like domain, IPR001590:Peptidase M12B, ADAM/reprolysin, IPR001762:Disintegrin domain, IPR002870:Peptidase M12B, propeptide, IPR006586:ADAM, cysteine-rich, IPR013032:EGF-like, conserved site, IPR034027:Reprolysin domain, adamalysin-type, IPR024079:Metallopeptidase, catalytic domain, IPR013111:EGF-like domain, extracellular" CG42252 27-Aug-18 DroID_v2018_08 "Drer\adam12, Drer\zgc:174164, Drer\adam17b, Drer\adam9, Drer\adam11, Drer\adam28, Drer\adam22, Drer\adam17a, Drer\adam19b, Drer\adam8a, Drer\adam19a, Drer\adam8b, Drer\adam15, Drer\adam23a" - "Cele\tag-275, Cele\unc-71, Cele\adm-4, Cele\K08B4.2, Cele\adm-2, Cele\F27D9.7" "Xtro\adam23, Xtro\adam11, Xtro\adam33, Xtro\adam12, Xtro\adam9" "Mmus\Adam26b, Mmus\Adam1a, Mmus\Adam24, Mmus\Adam19, Mmus\Adam39, Mmus\Adam17, Mmus\Adam15, Mmus\Adam6a, Mmus\Adam12, Mmus\Adam32, Mmus\Adam5, Mmus\Adam20, Mmus\Adam28, Mmus\Adam9, Mmus\Gm4787, Mmus\Adam11, Mmus\Adam3, Mmus\Adam4, Mmus\Adam34, Mmus\Adam22, Mmus\Gm5346, Mmus\Adam33, Mmus\Adam21, Mmus\Adamdec1, Mmus\Adam30, Mmus\Adam2, Mmus\Adam1b, Mmus\Adam25, Mmus\Adam7, Mmus\Adam26a, Mmus\Adam18, Mmus\Adam23, Mmus\Adam29, Mmus\Adam6b, Mmus\Adam8" "Hsap\ADAM8, Hsap\ADAM19, Hsap\ADAMDEC1, Hsap\ADAM11, Hsap\ADAM9, Hsap\ADAM18, Hsap\ADAM2, Hsap\ADAM21, Hsap\ADAM28, Hsap\ADAM23, Hsap\ADAM12, Hsap\ADAM33, Hsap\ADAM29, Hsap\ADAM22, Hsap\ADAM20, Hsap\ADAM17, Hsap\ADAM7, Hsap\ADAM32, Hsap\ADAM30, Hsap\ADAM15" DRSC20161 K 0.349532796 0.981301964 0.50742409 0.704442635 -1.675367721 -0.850084718 FBgn0036785 CG13700 - http://flybase.org/reports/FBgn0036785 protein_coding_gene - - - CG13700 - CG13700 27-Aug-18 DroID_v2018_08 - - Cele\pqn-8 - - - viable FBgn0065134 l(3)SH123 lethal (3) SH123 http://flybase.org/reports/FBgn0065134 gene - - - "l(3)SH123, l(2)SH3 123" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0261001 AGAR-53 Autosomal general anesthetic resistant 53 http://flybase.org/reports/FBgn0261001 gene - - - AGAR-53 - - 27-Aug-18 DroID_v2018_08 - - - - - - "chemical resistant,dominant" FBgn0038677 CG14284 - http://flybase.org/reports/FBgn0038677 protein_coding_gene - - - CG14284 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065678 l(2)SH0671 lethal (2) SH0671 http://flybase.org/reports/FBgn0065678 gene - - - "l(2)SH0671, l(2)SH2 0671" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0028069 l(3)S090314 lethal (3) S090314 http://flybase.org/reports/FBgn0028069 gene - - - "0903/14, l(3)S090314" - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,lethal,recessive" FBgn0084568 E-2fa Enhancer on chromosome 2-complementation group fa http://flybase.org/reports/FBgn0084568 gene - - - "E-2f, E-2fa" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0020805 ms(3)1100A male sterile (3) 1100A http://flybase.org/reports/FBgn0020805 - gene - - - ms(3)1100A - - 27-Aug-18 DroID_v2018_08 - - - - - - male sterile FBgn0083283 E(smoDN)2169 Enhancer of smoDN 2169 http://flybase.org/reports/FBgn0083283 gene - - - E(smoDN)2169 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0022972 snRNP42K snRNP42K http://flybase.org/reports/FBgn0022972 - gene - - - "42K, snRNP42K" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0027320 l(1)G0062 lethal (1) G0062 http://flybase.org/reports/FBgn0027320 - gene - - - l(1)G0062 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0069165 mcl(3)Z1492 mcl(3)Z1492 http://flybase.org/reports/FBgn0069165 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z1492 - - 27-Aug-18 DroID_v2018_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0011916 tRNA:Met-CAT-1-2 transfer RNA:Methionine-CAT 1-2 http://flybase.org/reports/FBgn0011916 "FBgn0003807, FBgn0052844, FBgn0060139" tRNA_gene AUG codon-amino acid adaptor activity ; GO:0033436 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033436 cytosol ; GO:0005829 | inferred by curator from GO:0033436 "CR32844, AE002787.trna22-MetCAT, tRNA:M:CAT:AE002787-b, tRNA:met2:48Bb, chr2R.trna81-MetCAT, tRNA-Met[CAU], tRNA-Met-CAT-1-2, tRNA:Met-CAT-1-2, tRNA:M2:48Bb" - CR32844 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065628 l(2)SH0791 lethal (2) SH0791 http://flybase.org/reports/FBgn0065628 gene - - - "l(2)SH0791, l(2)SH2 0791" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0016834 l(1)MZ21 lethal (1) MZ21 http://flybase.org/reports/FBgn0016834 - gene - - - "l(1)MZ21, M21" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0051876 Cpr30F Cuticular protein 30F http://flybase.org/reports/FBgn0051876 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model neurogenesis ; GO:0022008 | inferred from mutant phenotype extracellular matrix ; GO:0031012 | inferred from sequence model "CG5879, Cpr30F, CG31876, DmelCpr30F" IPR000618:Insect cuticle protein CG31876 27-Aug-18 DroID_v2018_08 - - Cele\fbxb-38 - - - "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0001774 l(1)M52 lethal (1) M52 http://flybase.org/reports/FBgn0001774 - gene - - - l(1)M52 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0003568 su(lz[34]) suppressor of lozenge-34 http://flybase.org/reports/FBgn0003568 - gene - - - "su(lz[34k]), su(lz[34])" - - 27-Aug-18 DroID_v2018_08 - - - - - - "female fertile,good" "female accessory gland,spermathecum,eye" FBgn0051864 Qtzl Quetzalcoatl http://flybase.org/reports/FBgn0051864 protein_coding_gene pyridoxal phosphate binding ; GO:0030170 | inferred from electronic annotation with InterPro:IPR010240 cysteine desulfurase activity ; GO:0031071 | inferred from electronic annotation with InterPro:IPR010240 [2Fe-2S] cluster assembly ; GO:0044571 | inferred from electronic annotation with InterPro:IPR010240 - "CG17749, CG31864, CG31864-PA, Qtzl" "IPR000192:Aminotransferase class V domain, IPR015424:Pyridoxal phosphate-dependent transferase, IPR010240:Cysteine desulfurase IscS, IPR015421:Pyridoxal phosphate-dependent transferase, major region, subdomain 1" CG31864 27-Aug-18 DroID_v2018_08 "Drer\scly, Drer\nfs1" Scer\NFS1 "Cele\B0205.6, Cele\F13H8.9" "Xtro\scly, Xtro\nfs1" "Mmus\Scly, Mmus\Nfs1" "Hsap\NFS1, Hsap\SCLY" "viable,sterile,recessive" FBgn0034792 YME1L - http://flybase.org/reports/FBgn0034792 protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR000642, InterPro:IPR005936 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000642, InterPro:IPR003959, InterPro:IPR003960" proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000642 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR005936 mitochondrion ; GO:0005739 | inferred from direct assay "DmCG3499, YME1L, dYME1L, CG3499" "IPR000642:Peptidase M41, IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR003960:ATPase, AAA-type, conserved site, IPR005936:Peptidase, FtsH, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG3499 27-Aug-18 DroID_v2018_08 "Drer\yme1l1a, Drer\spg7, Drer\yme1l1b, Drer\afg3l2" "Scer\YTA12, Scer\AFG3, Scer\YME1" "Cele\ppgn-1, Cele\ymel-1, Cele\spg-7" Xtro\yme1l1 "Mmus\Spg7, Mmus\Afg3l2, Mmus\Yme1l1, Mmus\Afg3l1" "Hsap\AFG3L2, Hsap\YME1L1, Hsap\SPG7" "viable,visible" trichogen cell FBgn0033590 CG13217 - http://flybase.org/reports/FBgn0033590 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE32413, CG13217" - CG13217 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0045858 e(Pi3K92E)alpha e(Pi3K92E)alpha http://flybase.org/reports/FBgn0045858 gene - - - "alpha, e(Pi3K92E)alpha" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0041597 l(2)PJ20 lethal (2) PJ20 http://flybase.org/reports/FBgn0041597 gene - - - l(2)PJ20 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0060311 l(3)S147912 lethal (3) S147912 http://flybase.org/reports/FBgn0060311 gene - - - "1479/12, l(3)S147912" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0264397 FCP-E - http://flybase.org/reports/FBgn0264397 gene - - - FCP-E - - 27-Aug-18 DroID_v2018_08 - - - - - - "follicle cell,somatic clone" FBgn0052328 tRNA:Glu-CTC-3-2 transfer RNA:Glutamic acid-CTC 3-2 http://flybase.org/reports/FBgn0052328 tRNA_gene GAG codon-amino acid adaptor activity ; GO:0033460 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033460 cytosol ; GO:0005829 | inferred by curator from GO:0033460 "CR32328, AE002584.trna4-GluCTC, tRNA:E:CTC:AE002584-b, chr3L.trna4-GluCTC, tRNA:Glu-CTC-3-2, tRNA:CR32328, tRNA-Glu-CTC-3-2, GAG" - CR32328 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030262 Vago Vago http://flybase.org/reports/FBgn0030262 protein_coding_gene - defense response to virus ; GO:0051607 | inferred from mutant phenotype defense response to virus ; GO:0051607 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from sequence model "CG2081, BcDNA:RH70969, Vago, DIGF-2" IPR029277:Single domain Von Willebrand factor type C domain CG2081 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" FBgn0051432 tRNA:Thr-TGT-2-5 transfer RNA:Threonine-TGT 2-5 http://flybase.org/reports/FBgn0051432 tRNA_gene ACA codon-amino acid adaptor activity ; GO:0033439 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033439 cytosol ; GO:0005829 | inferred by curator from GO:0033439 "AE002708.trna55-ThrTGT, tRNA[Thr][[3]], tRNA:thr3:87BC, tRNA:T3:87BC, tRNA:T:TGT:AE002708-b, CR31432, tRNA[[Thr]], chr3R.trna61-ThrTGT, tRNA-Thr-TGT-2-5, tRNA:Thr-TGT-2-5, tRNA:CR31432, ACA" - CR31432 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031455 Snapin SNAP associated protein http://flybase.org/reports/FBgn0031455 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Dysb intracellular protein transport ; GO:0006886 | inferred from electronic annotation with InterPro:IPR017246 neurotransmitter secretion ; GO:0007269 | non-traceable author statement synaptic vesicle exocytosis ; GO:0016079 | inferred from sequence or structural similarity regulation of homeostatic process ; GO:0032844 | inferred from mutant phenotype synaptic vesicle priming ; GO:0016082 | non-traceable author statement BLOC-1 complex ; GO:0031083 | inferred from sequence or structural similarity with HGNC:17145 synaptic vesicle ; GO:0008021 | inferred from direct assay synaptic vesicle ; GO:0008021 | non-traceable author statement "CG9958, CG32951, snapin, Dromel_CG9960_CG9958_FBtr007773_snapin_uORF, Snapin, NP_722835, SNAPIN" "IPR017246:Snapin, IPR028119:Snapin/Pallidin/Snn1" CG9958 27-Aug-18 DroID_v2018_08 Drer\snapin - Cele\snpn-1 Xtro\snapin Mmus\Snapin Hsap\SNAPIN "lethal - all die before end of pupal stage,some die during pupal stage,neurophysiology defective,drug conditional,female fertile" DRSC00736 E -0.117033922 0.993273659 1.590928682 0.825585157 0.007598632 -0.001642737 FBgn0052455 CG32455 - http://flybase.org/reports/FBgn0052455 protein_coding_gene - - - CG32455 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002752 mit(1)2 mitotic 2 http://flybase.org/reports/FBgn0002752 - gene molecular_function ; GO:0003674 | no biological data available mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mit(1)2 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,heat sensitive" FBgn0083048 snoRNA:Psi18S-1377d snoRNA:Psi18S-1377d http://flybase.org/reports/FBgn0083048 snoRNA_gene - - - "snoRNA:Psi18S-1377d, Psi18S-1377d, psi18S-1377d, CR34626, chr3R:26032931..26033021" - CR34626 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263231 bel belle http://flybase.org/reports/FBgn0263231 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR011545 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from mutant phenotype ATP-dependent RNA helicase activity ; GO:0004004 | inferred from sequence or structural similarity with SGD:S000005730 regulation of gene expression ; GO:0010468 | inferred from mutant phenotype RNA secondary structure unwinding ; GO:0010501 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 ecdysone-mediated induction of salivary gland cell autophagic cell death ; GO:0035072 | inferred from mutant phenotype mitotic sister chromatid segregation ; GO:0000070 | inferred from mutant phenotype translational initiation ; GO:0006413 | inferred from biological aspect of ancestor with PANTHER:PTN000619593 instar larval development ; GO:0002168 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype RNA interference ; GO:0016246 | inferred from mutant phenotype spermatid development ; GO:0007286 | inferred from mutant phenotype male germ-line stem cell population maintenance ; GO:0036098 | inferred from mutant phenotype microtubule associated complex ; GO:0005875 | inferred from direct assay P granule ; GO:0043186 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay RISC complex ; GO:0016442 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "psg9, bel, BEL, CG9748, DmRH6, cg9748, cap, ms(3)neo30, l(3)85Ac, L3, anon-85Ab, ms(3)Pneo85A, l(3)L3, belle, l(3)S097074, l(3)S047110, l(3)L4740, Bel" "IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR014014:RNA helicase, DEAD-box type, Q motif, IPR000629:ATP-dependent RNA helicase DEAD-box, conserved site, IPR001650:Helicase, C-terminal, IPR011545:DEAD/DEAH box helicase domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG9748 27-Aug-18 DroID_v2018_08 "Drer\ddx3a, Drer\ddx3b" "Scer\MRH4, Scer\DBP1, Scer\DED1" "Cele\glh-1, Cele\vbh-1, Cele\glh-3, Cele\laf-1, Cele\glh-2" Xtro\ddx3x "Mmus\Ddx3x, Mmus\Ddx3y, Mmus\Ddx4, Mmus\D1Pas1" "Hsap\DDX3Y, Hsap\DDX3X, Hsap\DDX4" DRSC25066 IK -2.737597649 -0.844103717 -0.809998272 0.190823138 0.35739607 3.248510243 FBgn0036192 Pldn Pallidin http://flybase.org/reports/FBgn0036192 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Blos1 eye pigment granule organization ; GO:0008057 | inferred from mutant phenotype intracellular transport ; GO:0046907 | inferred from biological aspect of ancestor with PANTHER:PTN001583105 BLOC-1 complex ; GO:0031083 | inferred from sequence or structural similarity with HGNC:8549 BLOC-1 complex ; GO:0031083 | inferred from biological aspect of ancestor with PANTHER:PTN001583105 transport vesicle ; GO:0030133 | inferred from biological aspect of ancestor with PANTHER:PTN001583105 extrinsic component of membrane ; GO:0019898 | inferred from biological aspect of ancestor with PANTHER:PTN001583105 "CG14133, Pallidin, NP_648494, pallidin, Pldn, pldn" "IPR017242:BLOC-1 complex, pallidin subunit, IPR028119:Snapin/Pallidin/Snn1" CG14133 27-Aug-18 DroID_v2018_08 Drer\bloc1s6 - - Xtro\bloc1s6 Mmus\Bloc1s6 Hsap\BLOC1S6 "eye color defective,viable" FBgn0067329 3F43 3F43 http://flybase.org/reports/FBgn0067329 gene molecular_function ; GO:0003674 | no biological data available imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available 3F43 - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,somatic clone" "wing sensillum,ectopic,somatic clone" FBgn0085540 lncRNA:CR40947 - http://flybase.org/reports/FBgn0085540 non_protein_coding_gene - - - "CR40947, CG40947" - CR40947 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051913 CG31913 - http://flybase.org/reports/FBgn0051913 protein_coding_gene RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000080456 structural constituent of ribosome ; GO:0003735 | inferred from biological aspect of ancestor with PANTHER:PTN000080456 translation ; GO:0006412 | inferred from biological aspect of ancestor with PANTHER:PTN000080456 cytosolic large ribosomal subunit ; GO:0022625 | inferred from biological aspect of ancestor with PANTHER:PTN000080456 "NEST:bs23g06, NEST:bs28e01, NEST:bs35c08, NEST:bs14h07, NEST:bs09g05, CG31913" IPR014807:Cytochrome oxidase assembly protein 1 CG31913 27-Aug-18 DroID_v2018_08 "Drer\coa1, Drer\rpl37" "Scer\RPL37A, Scer\RPL37B" "Cele\T23F2.2, Cele\Y38C1AA.14" Xtro\coa1 - Hsap\COA1 viable FBgn0026224 l(1)16Fq lethal (1) 16Fq http://flybase.org/reports/FBgn0026224 - gene - - - "ME-V, l(1)16Fq" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0065653 l(2)SH0728 lethal (2) SH0728 http://flybase.org/reports/FBgn0065653 gene - - - "l(2)SH0728, l(2)SH2 0728" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0259711 CG42365 - http://flybase.org/reports/FBgn0259711 protein_coding_gene - - - "CG42365, CG15675" - CG42365 27-Aug-18 DroID_v2018_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary" FBgn0011060 l(1)Q13 lethal (1) Q13 http://flybase.org/reports/FBgn0011060 FBgn0010210 gene - - - l(1)Q13 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0040553 CG14374 - http://flybase.org/reports/FBgn0040553 protein_coding_gene - - - CG14374 - CG14374 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0010401 Os-C Os-C http://flybase.org/reports/FBgn0010401 - protein_coding_gene - biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "Os-c, OS-C, CG3250, Os-C" - CG3250 27-Aug-18 DroID_v2018_08 - - - - - - adult stage " sacculus

, antennal segment 3

" "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0058040 CG40040 - http://flybase.org/reports/FBgn0058040 protein_coding_gene - - - CG40040 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002750 misp misstep http://flybase.org/reports/FBgn0002750 - gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available misp - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "embryonic/first instar larval cuticle,maternal effect,embryonic segment" FBgn0033729 Cpr49Af Cuticular protein 49Af http://flybase.org/reports/FBgn0033729 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr49Af, CG8510, DmelCpr49Af" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG8510 27-Aug-18 DroID_v2018_08 Drer\LOC100003040 - "Cele\sdz-30, Cele\math-34, Cele\F44F1.4" - "Mmus\H2-K1, Mmus\2410137M14Rik" - FBgn0037964 CG14731 - http://flybase.org/reports/FBgn0037964 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR017849, InterPro:IPR017850" "metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR017849, InterPro:IPR017850" - "CG14731, gi7299531, gi21483202" "IPR004245:Protein of unknown function DUF229, IPR017850:Alkaline-phosphatase-like, core domain, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha" CG14731 27-Aug-18 DroID_v2018_08 - - "Cele\M03F8.5, Cele\F32D8.2, Cele\R03G8.1, Cele\F10C2.3, Cele\Y41E3.1, Cele\F07C3.3, Cele\F15H10.7, Cele\T23E1.1, Cele\R03G8.3, Cele\Y38A10A.2, Cele\K03A11.4, Cele\T07G12.3, Cele\F32G8.2, Cele\Y73F8A.35" - - - "viable,fertile" FBgn0046118 E(To)8 E(To)8 http://flybase.org/reports/FBgn0046118 gene - - - E(To)8 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0028214 l(3)S009720 lethal (3) S009720 http://flybase.org/reports/FBgn0028214 gene - - - "0097/20, l(3)S009720" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0033865 CG6220 - http://flybase.org/reports/FBgn0033865 protein_coding_gene "transcription factor activity, RNA polymerase II transcription factor binding ; GO:0001076 | inferred from sequence or structural similarity with SGD:S000004410 transcription factor activity, RNA polymerase II transcription factor binding ; GO:0001076 | inferred from biological aspect of ancestor with PANTHER:PTN000279609 RNA polymerase II core binding ; GO:0000993 | inferred from biological aspect of ancestor with PANTHER:PTN000279609" negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from sequence or structural similarity with HGNC:16783 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex ; GO:0034402 | inferred from biological aspect of ancestor with PANTHER:PTN000279609 positive regulation of transcription elongation from RNA polymerase II promoter ; GO:0032968 | inferred from biological aspect of ancestor with PANTHER:PTN000279609 histone modification ; GO:0016570 | inferred from biological aspect of ancestor with PANTHER:PTN000279609 Cdc73/Paf1 complex ; GO:0016593 | inferred from sequence or structural similarity with SGD:S000004410 Cdc73/Paf1 complex ; GO:0016593 | inferred from biological aspect of ancestor with PANTHER:PTN000279609 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:16783 CG6220 "IPR007852:Cdc73/Parafibromin, IPR031336:Cell division control protein 73, C-terminal, IPR032041:Paf1 complex subunit Cdc73, N-terminal domain" CG6220 27-Aug-18 DroID_v2018_08 Drer\cdc73 Scer\CDC73 Cele\cdc-73 Xtro\cdc73 Mmus\Cdc73 Hsap\CDC73 viable FBgn0011231 sdl seedless http://flybase.org/reports/FBgn0011231 - gene - spermatid development ; GO:0007286 | inferred from mutant phenotype - sdl - - 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,recessive" FBgn0032925 CG9246 - http://flybase.org/reports/FBgn0032925 protein_coding_gene transcription corepressor activity ; GO:0003714 | inferred from biological aspect of ancestor with PANTHER:PTN000976013 histone binding ; GO:0042393 | inferred from biological aspect of ancestor with PANTHER:PTN000976013 repressing transcription factor binding ; GO:0070491 | inferred from biological aspect of ancestor with PANTHER:PTN000976013 neurogenesis ; GO:0022008 | inferred from mutant phenotype ribosomal large subunit biogenesis ; GO:0042273 | inferred from biological aspect of ancestor with PANTHER:PTN000293925 negative regulation of histone acetylation ; GO:0035067 | inferred from biological aspect of ancestor with PANTHER:PTN000976013 negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from biological aspect of ancestor with PANTHER:PTN000976013 nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000293925 nucleoplasm ; GO:0005654 | inferred from biological aspect of ancestor with PANTHER:PTN000293925 nucleolus ; GO:0005730 | inferred from sequence or structural similarity with HGNC:24517 Noc2p-Noc3p complex ; GO:0030691 | inferred from biological aspect of ancestor with PANTHER:PTN000293925 Noc1p-Noc2p complex ; GO:0030690 | inferred from biological aspect of ancestor with PANTHER:PTN000293925 CG9246 "IPR005343:Nucleolar complex protein 2, IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical" CG9246 27-Aug-18 DroID_v2018_08 Drer\noc2l Scer\NOC2 Cele\pro-2 Xtro\noc2l Mmus\Noc2l Hsap\NOC2L "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0002789 Mp20 Muscle protein 20 http://flybase.org/reports/FBgn0002789 "FBgn0003740, FBgn0026854" protein_coding_gene actin binding ; GO:0003779 | inferred from sequence or structural similarity myoblast fusion ; GO:0007520 | inferred from mutant phenotype cell adhesion ; GO:0007155 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype regulation of myoblast fusion ; GO:1901739 | inferred from mutant phenotype - "DMMP20, Dmmp20, CG4696, mp20, Tpn, Mp20, MP20" "IPR000557:Calponin repeat, IPR001715:Calponin homology domain, IPR003096:Smooth muscle protein/calponin" CG4696 27-Aug-18 DroID_v2018_08 "Drer\cnn2, Drer\cnn3b, Drer\cnn1b, Drer\tagln3b, Drer\tagln2, Drer\tagln, Drer\cnn3a, Drer\tagln3a, Drer\cnn1a, Drer\iqgap2" "Scer\SCP1, Scer\IQG1" "Cele\cpn-2, Cele\pes-7, Cele\cpn-1, Cele\cpn-3" "Xtro\tagln2, Xtro\cnn3, Xtro\cnn1, Xtro\tagln, Xtro\cnn2" "Mmus\Cnn2, Mmus\Iqgap1, Mmus\Iqgap3, Mmus\Cnn3, Mmus\Tagln2, Mmus\Cnn1, Mmus\Tagln, Mmus\Tagln3" "Hsap\CNN3, Hsap\CNN2, Hsap\TAGLN2, Hsap\TAGLN, Hsap\IQGAP1, Hsap\TAGLN3, Hsap\IQGAP3, Hsap\CNN1" " embryonic stage | 12-24 hr , adult stage , prepupal stage , pupal stage | early " adult stage synchronous muscle

"viable,visible" "dorsal acute muscle 1,nucleus | supernumeraryeve.eme,trichogen cell,supernumerary,tormogen cell,embryonic myoblast,dorsal transverse muscle,ventral acute muscle 2,segment border muscle,nucleushow-24B" FBgn0051675 CG31675 - http://flybase.org/reports/FBgn0051675 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE19849, CG31675" - CG31675 27-Aug-18 DroID_v2018_08 - - "Cele\C15H9.9, Cele\K11H12.6, Cele\K11H12.7" - - - viable FBgn0026380 Prosbeta3 Proteasome beta3 subunit http://flybase.org/reports/FBgn0026380 - protein_coding_gene "threonine-type endopeptidase activity ; GO:0004298 | inferred from electronic annotation with InterPro:IPR001353, InterPro:IPR023333 endopeptidase activity ; GO:0004175 | contributes_to inferred by curator from GO:0005839" neurogenesis ; GO:0022008 | inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred by curator from GO:0005839 "proteasome core complex, beta-subunit complex ; GO:0019774 | inferred from electronic annotation with InterPro:IPR033811 proteasome core complex ; GO:0005839 | inferred from direct assay proteasome complex ; GO:0000502 | inferred from direct assay" "Prosbeta3, CG11981, 11981, Beta-3, beta3, Pros beta3, beta-3" "IPR001353:Proteasome, subunit alpha/beta, IPR016050:Proteasome beta-type subunit, conserved site, IPR023333:Proteasome B-type subunit, IPR033811:Proteasome beta 3 subunit, IPR029055:Nucleophile aminohydrolases, N-terminal" CG11981 27-Aug-18 DroID_v2018_08 "Drer\psmb3, Drer\p4hb" Scer\PUP3 Cele\pbs-3 Xtro\psmb3 Mmus\Psmb3 Hsap\PSMB3 "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC16801 IE -3.090109855 -5.477058347 -3.845298976 -2.891937368 1.281761475 -0.036620931 FBgn0002206 l(3)67BDd lethal (3) 67BDd http://flybase.org/reports/FBgn0002206 - gene - - - l(3)67BDd - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0014364 myoblast-specific myoblast specific http://flybase.org/reports/FBgn0014364 - gene - - - "mas, myoblast-specific" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040487 BobA Brother of Bearded A http://flybase.org/reports/FBgn0040487 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with neur Notch signaling pathway ; GO:0007219 | inferred from mutant phenotype sensory organ development ; GO:0007423 | inferred from mutant phenotype sensory organ precursor cell fate determination ; GO:0016360 | inferred from mutant phenotype cell fate specification ; GO:0001708 | inferred from mutant phenotype defense response to bacterium ; GO:0042742 | inferred from mutant phenotype - "CG12487, bobA, Bob-A, Bob, BobA" - CG12487 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile,visible,lethal" "macrochaeta,microchaeta,external sensory organ precursor cell & dorsal mesothoracic disc-537.4,wing sensillum & wing veinBx-MS1096,wing margin bristle,wing sensillum & wing vein69B,tormogen cell,trichogen cell" FBgn0011660 Pms2 Pms2 http://flybase.org/reports/FBgn0011660 FBgn0024325 protein_coding_gene "mismatched DNA binding ; GO:0030983 | inferred from electronic annotation with InterPro:IPR002099, InterPro:IPR013507 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002099, InterPro:IPR013507, InterPro:IPR014790 ATPase activity ; GO:0016887 | inferred from biological aspect of ancestor with PANTHER:PTN000008161 single-stranded DNA binding ; GO:0003697 | inferred from biological aspect of ancestor with PANTHER:PTN000008161" mismatch repair ; GO:0006298 | inferred from biological aspect of ancestor with PANTHER:PTN000008161 MutLalpha complex ; GO:0032389 | inferred from biological aspect of ancestor with PANTHER:PTN000008284 microtubule associated complex ; GO:0005875 | inferred from direct assay "pms2, dmlh2, dmlh-2, dpms2, Mlh2, CG8169, Pms2" "IPR002099:DNA mismatch repair protein family, IPR003594:Histidine kinase-like ATPase, C-terminal domain, IPR013507:DNA mismatch repair protein, C-terminal, IPR014721:Ribosomal protein S5 domain 2-type fold, subgroup, IPR014762:DNA mismatch repair, conserved site, IPR014790:MutL, C-terminal, dimerisation, IPR020568:Ribosomal protein S5 domain 2-type fold, IPR028831:DNA mismatch repair protein Pms1" CG8169 27-Aug-18 DroID_v2018_08 "Drer\pms2, Drer\pms1, Drer\rsph10b" "Scer\PMS1, Scer\MLH2" Cele\pms-2 "Xtro\rsph10b, Xtro\pms2, Xtro\pms1" "Mmus\Pms1, Mmus\Lef1, Mmus\Pms2" "Hsap\RSPH10B2, Hsap\PMS1, Hsap\PMS2, Hsap\LOC107984056, Hsap\LEF1, Hsap\RSPH10B" viable FBgn0267044 CG45488 - http://flybase.org/reports/FBgn0267044 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG45488 - CG45488 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031873 Gas41 Gas41 http://flybase.org/reports/FBgn0031873 protein_coding_gene histone acetyltransferase activity ; GO:0004402 | contributes_to inferred from direct assay heterochromatin organization involved in chromatin silencing ; GO:0070868 | inferred from mutant phenotype RNA interference ; GO:0016246 | inferred from mutant phenotype protein localization to heterochromatin ; GO:0097355 | inferred from mutant phenotype transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:7134 inferred from sequence or structural similarity with HGNC:7136 inferred from sequence or structural similarity with SGD:S000005051 inferred from sequence or structural similarity with SGD:S000006050 histone exchange ; GO:0043486 | inferred from direct assay histone acetylation ; GO:0016573 | inferred from direct assay histone acetyltransferase complex ; GO:0000123 | inferred from physical interaction with pont NuA4 histone acetyltransferase complex ; GO:0035267 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay transcription factor TFIID complex ; GO:0005669 | inferred from sequence or structural similarity with HGNC:7134 inferred from sequence or structural similarity with HGNC:7136 inferred from sequence or structural similarity with SGD:S000005051 inferred from sequence or structural similarity with SGD:S000006050 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:24859 "GAS41, dGas41, CG9207, Gas41" IPR005033:YEATS CG9207 27-Aug-18 DroID_v2018_08 "Drer\mllt1a, Drer\mllt1b, Drer\mllt3, Drer\yeats4, Drer\yeats2" "Scer\SAS5, Scer\YAF9, Scer\TAF14" "Cele\gfl-1, Cele\Y105E8B.7" "Xtro\mllt3, Xtro\mllt1, Xtro\yeats2, Xtro\yeats4" "Mmus\Mllt3, Mmus\Yeats4, Mmus\Mllt1, Mmus\Yeats2" "Hsap\MLLT3, Hsap\YEATS2, Hsap\MLLT1, Hsap\YEATS4" viable FBgn0020608 anon-12Db anon-12Db http://flybase.org/reports/FBgn0020608 - gene - - - "D1, anon-12Db" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259332 C434.2 - http://flybase.org/reports/FBgn0259332 gene - - - C434.2 - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,lethal" "wing vein,wing hair,chaeta" FBgn0032613 CG13283 - http://flybase.org/reports/FBgn0032613 protein_coding_gene metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR000718 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000718 - CG13283 "IPR024079:Metallopeptidase, catalytic domain, IPR000718:Peptidase M13" CG13283 27-Aug-18 DroID_v2018_08 "Drer\ece2b, Drer\ece1, Drer\phex, Drer\mmel1" - "Cele\nep-24, Cele\nep-6" "Xtro\ecel1, Xtro\ece1, Xtro\mmel1, Xtro\ece2" "Mmus\Phex, Mmus\Ecel1, Mmus\Ece1, Mmus\Mmel1, Mmus\Ece2, Mmus\Mme, Mmus\Kel" "Hsap\ECEL1, Hsap\MMEL1, Hsap\KEL, Hsap\PHEX, Hsap\ECE1, Hsap\MME, Hsap\ECE2" viable FBgn0060357 l(3)S140713a lethal (3) S140713a http://flybase.org/reports/FBgn0060357 gene - - - "1407/13, l(3)S140713a" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0005138 l(2)74i lethal (2) 74i http://flybase.org/reports/FBgn0005138 - gene - - - l(2)74i - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0037466 CG1965 - http://flybase.org/reports/FBgn0037466 protein_coding_gene "transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001078 | inferred from biological aspect of ancestor with PANTHER:PTN000259143 RNA polymerase II core promoter proximal region sequence-specific DNA binding ; GO:0000978 | inferred from biological aspect of ancestor with PANTHER:PTN000259143" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR012890, InterPro:IPR022783 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013" precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay CG1965 "IPR012890:GC-rich sequence DNA-binding factor, IPR022783:GC-rich sequence DNA-binding factor domain" CG1965 27-Aug-18 DroID_v2018_08 "Drer\zgc:158234, Drer\gcfc2" - Cele\F43G9.12 "Xtro\paxbp1, Xtro\gcfc2" "Mmus\Paxbp1, Mmus\Gcfc2" "Hsap\PAXBP1, Hsap\GCFC2" lethal FBgn0035718 CG14820 - http://flybase.org/reports/FBgn0035718 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000834 metallocarboxypeptidase activity ; GO:0004181 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 protein binding ; GO:0005515 | inferred from physical interaction with egg "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000834, InterPro:IPR003146" extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 CG14820 "IPR000834:Peptidase M14, carboxypeptidase A, IPR009020:Protease propeptides/proteinase inhibitor I9, IPR034223:Insect gut carboxypeptidase-like, carboxypeptidase domain, IPR003146:Carboxypeptidase, activation peptide" CG14820 27-Aug-18 DroID_v2018_08 "Drer\cpa2, Drer\cpa6, Drer\cpa4, Drer\cpb2, Drer\cpo, Drer\cpa5, Drer\cpb1, Drer\cpa1" Scer\ECM14 "Cele\W01A8.6, Cele\ZC434.9, Cele\Y59C2A.1, Cele\F02D8.4, Cele\suro-1, Cele\Y47G6A.19, Cele\T06A4.3, Cele\T06A4.1, Cele\Y18H1A.9" "Xtro\cpa1, Xtro\LOC100487462, Xtro\LOC100489361, Xtro\cpo, Xtro\cpb1, Xtro\cpb2, Xtro\cpa3" "Mmus\Cpb2, Mmus\Cpa6, Mmus\Cpa4, Mmus\Cpa5, Mmus\Cpa2, Mmus\Cpb1, Mmus\Cpa3, Mmus\Cpa1" "Hsap\CPA5, Hsap\CPB1, Hsap\CPA2, Hsap\CPB2, Hsap\CPA6, Hsap\CPA3, Hsap\CPO, Hsap\CPA4, Hsap\CPA1" "partially lethal - majority die,some die during pupal stage" FBgn0035760 CG8607 - http://flybase.org/reports/FBgn0035760 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR011060, InterPro:IPR013785" metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR011060 - CG8607 "IPR005137:Membrane complex biogenesis protein, BtpA family, IPR011060:Ribulose-phosphate binding barrel" CG8607 27-Aug-18 DroID_v2018_08 Drer\zgc:162297 - "Cele\fipr-15, Cele\F13E9.13" Xtro\LOC549154 - - viable FBgn0052736 CG32736 - http://flybase.org/reports/FBgn0052736 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG32736, CG14429, BcDNA:RE60462" IPR028183:Uncharacterised protein family UPF0640 CG32736 27-Aug-18 DroID_v2018_08 "Drer\smim4, Drer\si:ch211-68a17.7, Drer\lin37" - Cele\lin-37 Xtro\lin37 Mmus\Smim4 "Hsap\C12orf73, Hsap\LIN37, Hsap\SMIM4" FBgn0065673 l(2)SH0678 lethal (2) SH0678 http://flybase.org/reports/FBgn0065673 gene - - - "l(2)SH0678, l(2)SH2 0678" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0031020 Naa15-16 N(alpha)-acetyltransferase 15/16 http://flybase.org/reports/FBgn0031020 protein_coding_gene peptide alpha-N-acetyltransferase activity ; GO:0004596 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000511059 N-terminal peptidyl-methionine acetylation ; GO:0017196 | inferred from biological aspect of ancestor with PANTHER:PTN000511059 neurogenesis ; GO:0022008 | inferred from mutant phenotype mitotic spindle ; GO:0072686 | inferred from direct assay NatA complex ; GO:0031415 | inferred from biological aspect of ancestor with PANTHER:PTN000511117 NatA complex ; GO:0031415 | inferred from direct assay protein acetyltransferase complex ; GO:0031248 | inferred from physical interaction with UniProtKB:Q9NHD5 "CG12202, dNat1, l(1)G0311, Nat1, Naa15, dNaa15, Naa15-16, Naa15/16, NAA15-16" "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat, IPR021183:N-terminal acetyltransferase A, auxiliary subunit" CG12202 27-Aug-18 DroID_v2018_08 "Drer\naa15a, Drer\naa15b" Scer\NAT1 Cele\hpo-29 "Xtro\naa15, Xtro\naa16" "Mmus\Naa15, Mmus\Naa16" "Hsap\NAA16, Hsap\NAA15" "viable,fertile,lethal,recessive,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC19440 IE 1.118109638 2.123228374 1.101715375 1.73970854 0.055528706 -0.511190298 FBgn0034617 Panx Panoramix http://flybase.org/reports/FBgn0034617 protein_coding_gene molecular_function ; GO:0003674 | no biological data available piRNA biosynthetic process ; GO:1990511 | inferred from direct assay positive regulation of methylation-dependent chromatin silencing ; GO:0090309 | inferred from direct assay inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "CG9754, Panx, pan, Silencio" - CG9754 27-Aug-18 DroID_v2018_08 - - - - - - "viable,female sterile" FBgn0046839 l(3)A4-4L1 lethal (3) A4-4L1 http://flybase.org/reports/FBgn0046839 gene - - - l(3)A4-4L1 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0263845 lncRNA:CR43706 - http://flybase.org/reports/FBgn0263845 non_protein_coding_gene - - - CR43706 - CR43706 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265921 lncRNA:CR44710 - http://flybase.org/reports/FBgn0265921 non_protein_coding_gene - - - "CR44710, lincRNA.1029" - CR44710 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262580 CG43120 - http://flybase.org/reports/FBgn0262580 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43120 "IPR000210:BTB/POZ domain, IPR011333:SKP1/BTB/POZ domain" CG43120 27-Aug-18 DroID_v2018_08 "Drer\btbd6b, Drer\btbd17b, Drer\btbd6a, Drer\btbd2, Drer\btbd3a, Drer\btbd3b" - - "Xtro\btbd1, Xtro\btbd2, Xtro\btbd3, Xtro\btbd6" "Mmus\Btbd6, Mmus\Btbd17, Mmus\Btbd1, Mmus\Btbd2, Mmus\Btbd3" "Hsap\BTBD3, Hsap\BTBD1, Hsap\BTBD2, Hsap\BTBD17, Hsap\BTBD6" FBgn0000195 blc blocked http://flybase.org/reports/FBgn0000195 - gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available blc - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,male sterile" "germline cell,female" FBgn0000687 flrdJ flight reduced J http://flybase.org/reports/FBgn0000687 - gene molecular_function ; GO:0003674 | no biological data available flight behavior ; GO:0007629 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "flrdI, flrdJ" - - 27-Aug-18 DroID_v2018_08 - - - - - - flight defective FBgn0022935 D19A D19A http://flybase.org/reports/FBgn0022935 - protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN001227002 DNA binding ; GO:0003677 | inferred from biological aspect of ancestor with PANTHER:PTN001227002" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from biological aspect of ancestor with PANTHER:PTN001227002" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001227002 "CG10269, D19A, d19a" "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG10269 27-Aug-18 DroID_v2018_08 "Drer\zgc:174268, Drer\znf770, Drer\znf1004, Drer\znf668, Drer\znf990, Drer\si:dkey-33c14.6, Drer\znf341, Drer\zgc:162948" Scer\PZF1 "Cele\eor-1, Cele\ZK546.5, Cele\Y55F3AM.14, Cele\Y37F4.6, Cele\Y48G8AL.10, Cele\hinf-1, Cele\hbl-1, Cele\sem-4" "Xtro\hic1, Xtro\znf668" "Mmus\Zfp672, Mmus\Plagl1, Mmus\Zfp341, Mmus\Zfp668" "Hsap\ZNF317, Hsap\ZNF555, Hsap\ZNF782, Hsap\ZNF284, Hsap\ZNF341, Hsap\ZNF221, Hsap\ZNF668, Hsap\ZNF43" viable DRSC11133 IEK -1.89875976 -2.851653906 -2.516288756 -4.184940303 0.494635396 1.650365893 FBgn0001048 fs(3)HO231 female sterile (3) HO231 http://flybase.org/reports/FBgn0001048 - gene - - - "fs(3)231A, fs(3)HO231" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033221 CG12825 - http://flybase.org/reports/FBgn0033221 protein_coding_gene - - integral component of membrane ; GO:0016021 | inferred from sequence model "CG12825, dmCG12825" - CG12825 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0262436 mir-310 mir-310 stem loop http://flybase.org/reports/FBgn0262436 miRNA_gene - response to nicotine ; GO:0035094 | inferred from mutant phenotype segmentation ; GO:0035282 | inferred from mutant phenotype head involution ; GO:0008258 | inferred from mutant phenotype cellular response to nitric oxide ; GO:0071732 | inferred from direct assay compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype - "mir-310, miR-310, Dme-miR-310, CR42995, Mir-310, CR33614, dme-mir-310, miR310, mIR-310" - CR42995 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible,lethal - all die before end of larval stage,some die during larval stage,lethal,partially lethal - majority die" "wing hair,wing" FBgn0039505 CG5934 - http://flybase.org/reports/FBgn0039505 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - CG5934 IPR019357:Predicted coiled-coil protein (DUF2205) CG5934 27-Aug-18 DroID_v2018_08 "Drer\scocb, Drer\scoca" - Cele\unc-69 Xtro\scoc Mmus\Scoc Hsap\SCOC viable FBgn0030592 CG9514 - http://flybase.org/reports/FBgn0030592 protein_coding_gene "oxidoreductase activity, acting on CH-OH group of donors ; GO:0016614 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR007867 flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR000172 oxidoreductase activity ; GO:0016491 | inferred from sequence or structural similarity with Eo" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR007867, InterPro:IPR023753 ecdysteroid metabolic process ; GO:0045455 | inferred from sequence or structural similarity with Eo inferred from genomic context with Eo" - "CG9514, Dm GMCdelta1" "IPR000172:Glucose-methanol-choline oxidoreductase, N-terminal, IPR007867:Glucose-methanol-choline oxidoreductase, C-terminal, IPR023753:FAD/NAD(P)-binding domain" CG9514 27-Aug-18 DroID_v2018_08 Drer\chdh - Cele\C34C6.4 - Mmus\Chdh Hsap\CHDH viable DRSC30059 K 0.878152916 0.267693627 0.167029725 0.592564886 0.343996625 -1.700268826 FBgn0036640 nxf2 nuclear RNA export factor 2 http://flybase.org/reports/FBgn0036640 protein_coding_gene - poly(A)+ mRNA export from nucleus ; GO:0016973 | inferred from biological aspect of ancestor with PANTHER:PTN000070434 nucleoplasm ; GO:0005654 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "NXF2, CG4118, nxf2" "IPR018222:Nuclear transport factor 2, eukaryote, IPR005637:TAP C-terminal (TAP-C) domain, IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like, IPR032710:NTF2-like domain, IPR030217:Nuclear RNA export factor, IPR009060:UBA-like" CG4118 27-Aug-18 DroID_v2018_08 "Drer\zgc:153681, Drer\nxf1" Scer\MEX67 "Cele\nxf-1, Cele\nxf-2" Xtro\nxf1 "Mmus\Nxf1, Mmus\Tmem223, Mmus\Nxf7, Mmus\Nxf2, Mmus\Nxf3" "Hsap\NXF1, Hsap\NXF2, Hsap\NXF3, Hsap\NXF2B, Hsap\NXF5" "female sterile,female fertile" DRSC10403 I -1.547157048 0.790849092 -0.046858054 0.276373273 -1.105280854 -0.112959855 FBgn0003479 spn-A spindle A http://flybase.org/reports/FBgn0003479 FBgn0011700 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR020587, InterPro:IPR020588 single-stranded DNA binding ; GO:0003697 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9W157 double-stranded DNA binding ; GO:0003690 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 recombinase activity ; GO:0000150 | inferred from sequence or structural similarity with HGNC:9817 endodeoxyribonuclease activity ; GO:0004520 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001415033 recombinase activity ; GO:0000150 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 DNA-dependent ATPase activity ; GO:0008094 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 four-way junction DNA binding ; GO:0000400 | inferred from biological aspect of ancestor with PANTHER:PTN001415033" "mitotic recombination-dependent replication fork processing ; GO:1990426 | inferred from electronic annotation with InterPro:IPR011941 oogenesis ; GO:0048477 | traceable author statement polarity specification of dorsal/ventral axis ; GO:0009951 | inferred from mutant phenotype oocyte fate determination ; GO:0030716 | inferred from mutant phenotype double-strand break repair via synthesis-dependent strand annealing ; GO:0045003 | inferred from mutant phenotype reciprocal meiotic recombination ; GO:0007131 | inferred from biological aspect of ancestor with PANTHER:PTN001489025 regulation of double-strand break repair via homologous recombination ; GO:0010569 | inferred from mutant phenotype DNA recombination ; GO:0006310 | inferred from sequence or structural similarity with HGNC:9817 polarity specification of anterior/posterior axis ; GO:0009949 | inferred from mutant phenotype intracellular mRNA localization ; GO:0008298 | traceable author statement karyosome formation ; GO:0030717 | inferred from mutant phenotype DNA repair ; GO:0006281 | inferred from sequence or structural similarity with HGNC:9817 germarium-derived oocyte fate determination ; GO:0007294 | inferred from genetic interaction with mus301 DNA recombinase assembly ; GO:0000730 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 response to ionizing radiation ; GO:0010212 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 mitotic recombination ; GO:0006312 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 oogenesis ; GO:0048477 | inferred from mutant phenotype intracellular mRNA localization ; GO:0008298 | inferred from mutant phenotype chromosome organization involved in meiotic cell cycle ; GO:0070192 | inferred from biological aspect of ancestor with PANTHER:PTN001489025 DNA repair ; GO:0006281 | inferred from genetic interaction with Blm, mus81 female meiotic division ; GO:0007143 | inferred from mutant phenotype strand invasion ; GO:0042148 | inferred from biological aspect of ancestor with PANTHER:PTN001415033 double-strand break repair ; GO:0006302 | inferred from mutant phenotype response to caffeine ; GO:0031000 | inferred from genetic interaction with MAGE" condensed nuclear chromosome ; GO:0000794 | inferred from biological aspect of ancestor with PANTHER:PTN001489025 nucleoplasm ; GO:0005654 | inferred from biological aspect of ancestor with PANTHER:PTN001489025 "DmRad51, spnA, dmRAD51, Rad51, Dm Rad51, D37788, DmRAD51, RAD51, CG7948, DMR, Dmrad51, DMR/DroRAD51, RA51, Rad51dm, DMR1, spn-A, rad51, Spn-A, RA51_DROME, dmrad51, SpnA" "IPR003593:AAA+ ATPase domain, IPR010995:DNA repair Rad51/transcription factor NusA, alpha-helical, IPR011941:DNA recombination/repair protein Rad51, IPR013632:DNA recombination and repair protein Rad51-like, C-terminal, IPR016467:DNA recombination and repair protein, RecA-like, IPR020587:DNA recombination and repair protein RecA, monomer-monomer interface, IPR020588:DNA recombination and repair protein RecA-like, ATP-binding domain, IPR033925:Rad51/DMC1/RadA, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG7948 27-Aug-18 DroID_v2018_08 "Drer\rad51, Drer\rad51b, Drer\dmc1, Drer\rad51d" "Scer\DMC1, Scer\RAD51" Cele\rad-51 "Xtro\rad51, Xtro\rad51d" "Mmus\Dmc1, Mmus\Rad51, Mmus\Rad51d, Mmus\Rad51b" "Hsap\DMC1, Hsap\RAD51D, Hsap\RAD51, Hsap\RAD51B" "viable,lethal,maternal effect,semi-fertile,radiation sensitive,dominant,DNA repair defective,meiotic cell cycle defective,female,lethal - all die before end of pupal stage,some die during pupal stage" "dorsal appendage,germline clone,chorion | dorsal | germline clone,egg,presumptive oocyte,karyosome,chorion,maternal effect,synaptonemal complexX3F),chorion | dorsalX3F),dorsal,oocyte,nurse cell,egg chamber,synaptonemal complex,germline cyst" DRSC16812 K -0.18460639 0.050961495 -0.157866144 0.030878465 2.326013271 0.759214734 FBgn0040905 CG15578 - http://flybase.org/reports/FBgn0040905 protein_coding_gene - - - CG15578 - CG15578 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0010343 HIS-C Histone complex http://flybase.org/reports/FBgn0010343 - protein_coding_gene - - - "his, HIS-C, histone, His-C" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0024712 anon-57Co anon-57Co http://flybase.org/reports/FBgn0024712 - gene - - - anon-57Co - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060778 l(3)S060711a lethal (3) S060711a http://flybase.org/reports/FBgn0060778 gene - - - "0607/11, l(3)S060711a" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0267478 asRNA:CR45828 - http://flybase.org/reports/FBgn0267478 non_protein_coding_gene - - - CR45828 - CR45828 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038750 CG4465 - http://flybase.org/reports/FBgn0038750 protein_coding_gene organic anion transmembrane transporter activity ; GO:0008514 | inferred from biological aspect of ancestor with PANTHER:PTN001936837 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001175408 CG4465 "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG4465 27-Aug-18 DroID_v2018_08 "Drer\oatx, Drer\LOC101884074, Drer\slc22a13, Drer\slc22a21, Drer\zgc:175176, Drer\slc22a5, Drer\slc22a4, Drer\slc22a6l, Drer\slc22a2, Drer\sv2, Drer\LOC100334012, Drer\slc22a7b.1, Drer\zmp:0000001102, Drer\slc22a7b.2, Drer\slc22a7b.3" "Scer\QDR1, Scer\YHK8, Scer\DTR1, Scer\TPO2, Scer\TPO1, Scer\FLR1, Scer\TPO3, Scer\QDR3, Scer\AQR1, Scer\QDR2" "Cele\T22F7.1, Cele\oct-2, Cele\K09E9.1" Xtro\slc22a6 "Mmus\Slc22a3, Mmus\Slc22a27, Mmus\Slc22a28, Mmus\Slc22a29, Mmus\Slc22a1, Mmus\Svop, Mmus\Slc22a7, Mmus\Slc22a4, Mmus\Slc22a2, Mmus\Slc22a16, Mmus\Slc22a23, Mmus\Slc22a30, Mmus\Slc22a14, Mmus\Slc22a26, Mmus\Sv2c, Mmus\Slc22a19, Mmus\Slc22a6, Mmus\Slc22a20, Mmus\Slc22a22, Mmus\Slc22a8" "Hsap\SLC22A7, Hsap\SV2C, Hsap\SV2B, Hsap\SLC22A12, Hsap\SLC22A3, Hsap\SLC22A1, Hsap\SLC22A11, Hsap\SVOP, Hsap\SLC22A2, Hsap\SLC22A6, Hsap\SLC22A25, Hsap\SLC22A9, Hsap\SLC22A10, Hsap\SLC22A24, Hsap\SLC22A23, Hsap\SLC22A8" "viable,fertile" DRSC15584 E -0.01569009 -0.207640764 -1.832399723 -0.003269499 0.456789135 0.528808937 FBgn0046645 anon-38D.21 anon-38D.21 http://flybase.org/reports/FBgn0046645 gene - - - "38D.21, anon-38D.21" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263898 A44 - http://flybase.org/reports/FBgn0263898 gene - - - A44 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,decreased cell number,somatic clone" "embryonic/larval brain,somatic clone" FBgn0065775 l(2)SH0454 lethal (2) SH0454 http://flybase.org/reports/FBgn0065775 gene - - - "l(2)SH0454, l(2)SH2 0454" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0082954 snoRNA:Psi28S-3571 snoRNA:Psi28S-3571 http://flybase.org/reports/FBgn0082954 snoRNA_gene - - - "snoRNA:Psi28S-3571, psi28s-3571, Psi 28S-3571, CR34611, chr3R:1423362..1423500" - CR34611 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0053194 CheA29a Chemosensory protein A 29a http://flybase.org/reports/FBgn0053194 protein_coding_gene molecular_function ; GO:0003674 | no biological data available sensory perception of chemical stimulus ; GO:0007606 | inferred from expression pattern detection of pheromone ; GO:0043695 | inferred from expression pattern extracellular region ; GO:0005576 | inferred from sequence model "CG33194, CheA29a" - CG33194 27-Aug-18 DroID_v2018_08 - - - - - - adult stage | male " prothoracic tarsal segment

, prothoracic tarsal segment 3

, prothoracic tarsal segment 2

, head

, prothoracic tarsal segment 1

, prothoracic tarsal segment 4

" "viable,fertile" DRSC21486 K -0.328872632 0.196732457 0.688702037 0.631062025 -1.575566016 -1.801877171 FBgn0002308 l(3)84Ff lethal (3) 84Ff http://flybase.org/reports/FBgn0002308 - gene - - - "l(3)EfK3, l(3)84Ff" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0039333 CG11917 - http://flybase.org/reports/FBgn0039333 protein_coding_gene - - - CG11917 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060604 l(3)S091104 lethal (3) S091104 http://flybase.org/reports/FBgn0060604 gene - - - "0911/04, l(3)S091104" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0065127 l(3)SH138 lethal (3) SH138 http://flybase.org/reports/FBgn0065127 gene - - - "l(3)SH138, l(2)SH3 138" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0001024 fs(3)A15 female sterile (3) A15 http://flybase.org/reports/FBgn0001024 - gene - - - fs(3)A15 - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive,mitotic cell cycle defective" "female reproductive system,spindle" FBgn0265646 lncRNA:CR44453 - http://flybase.org/reports/FBgn0265646 non_protein_coding_gene - - - "lincRNA.293, CR44453" - CR44453 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0066084 RpL41 Ribosomal protein L41 http://flybase.org/reports/FBgn0066084 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with SGD:S000002343 structural constituent of ribosome ; GO:0003735 | non-traceable author statement translation ; GO:0006412 | non-traceable author statement cytoplasmic translation ; GO:0002181 | traceable author statement cytoplasmic translation ; GO:0002181 | inferred from sequence or structural similarity with SGD:S000002343 nucleoplasm ; GO:0005654 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay nucleolus ; GO:0005730 | inferred from direct assay cytosolic large ribosomal subunit ; GO:0022625 | non-traceable author statement cytosol ; GO:0005829 | inferred from direct assay nuclear chromosome ; GO:0000228 | inferred from direct assay cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement cytosolic large ribosomal subunit ; GO:0022625 | inferred from sequence or structural similarity with SGD:S000002343 "pncr005:2R, CG30425, L41, BcDNA:RE63504, BEST:LP07070, BcDNA:LP07070, CR30425, RpL41, Rpl41" IPR007836:Ribosomal protein L41 CG30425 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040650 CG15456 - http://flybase.org/reports/FBgn0040650 protein_coding_gene - - - CG15456 "IPR011893:Selenoprotein, Rdx type, IPR012336:Thioredoxin-like fold" CG15456 27-Aug-18 DroID_v2018_08 "Drer\sepw2a, Drer\sepw2b, Drer\sepw1" - Cele\F28H7.4 Xtro\mien1 "Mmus\Mien1, Mmus\Selenow" "Hsap\MIEN1, Hsap\SELENOW" viable FBgn0266274 T:SS-trypsin Signal sequence of trypsin http://flybase.org/reports/FBgn0266274 engineered_foreign_region - - - T:SS-trypsin - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036440 CG17177 - http://flybase.org/reports/FBgn0036440 protein_coding_gene - - - CG17177 - CG17177 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060411 l(3)S130204b lethal (3) S130204b http://flybase.org/reports/FBgn0060411 gene - - - "1302/04, l(3)S130204b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0003341 scrp scarp http://flybase.org/reports/FBgn0003341 - gene - - - scrp - - 27-Aug-18 DroID_v2018_08 - - - - - - "eye,heat sensitive" FBgn0267182 lncRNA:CR45622 - http://flybase.org/reports/FBgn0267182 non_protein_coding_gene - - - CR45622 - CR45622 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0015449 l(1)9Fi lethal (1) 9Fi http://flybase.org/reports/FBgn0015449 - gene - - - l(1)9Fi - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0034422 CG7137 - http://flybase.org/reports/FBgn0034422 protein_coding_gene methylated histone binding ; GO:0035064 | inferred from biological aspect of ancestor with PANTHER:PTN000980278 methylated histone binding ; GO:0035064 | inferred from sequence or structural similarity with UniProtKB:O43159 S-adenosylmethionine-dependent methyltransferase activity ; GO:0008757 | inferred from biological aspect of ancestor with PANTHER:PTN000300315 chromatin silencing at rDNA ; GO:0000183 | inferred from sequence or structural similarity with UniProtKB:O43159 cellular response to glucose starvation ; GO:0042149 | inferred from biological aspect of ancestor with PANTHER:PTN000980278 chromatin silencing at rDNA ; GO:0000183 | inferred from biological aspect of ancestor with PANTHER:PTN000980278 regulation of transcription by glucose ; GO:0046015 | inferred from biological aspect of ancestor with PANTHER:PTN000980278 chromatin silencing complex ; GO:0005677 | inferred from biological aspect of ancestor with PANTHER:PTN000980278 nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000300315 rDNA heterochromatin ; GO:0033553 | inferred from biological aspect of ancestor with PANTHER:PTN000980278 nucleolus ; GO:0005730 | inferred from sequence or structural similarity with UniProtKB:O43159 rDNA heterochromatin ; GO:0033553 | inferred from sequence or structural similarity with UniProtKB:O43159 chromatin silencing complex ; GO:0005677 | inferred from sequence or structural similarity with UniProtKB:O43159 CG7137 "IPR007823:Ribosomal RNA processing protein 8, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG7137 27-Aug-18 DroID_v2018_08 Drer\si:ch211-149e23.3 Scer\RRP8 Cele\T07A9.8 - Mmus\Rrp8 Hsap\RRP8 "viable,visible" trichogen cell FBgn0037356 CG12170 - http://flybase.org/reports/FBgn0037356 protein_coding_gene "transferase activity, transferring acyl groups other than amino-acyl groups ; GO:0016747 | inferred from electronic annotation with InterPro:IPR017568" fatty acid biosynthetic process ; GO:0006633 | inferred from electronic annotation with InterPro:IPR017568 - "anon-WO0118547.367, CG12170" "IPR018201:Beta-ketoacyl synthase, active site, IPR014030:Beta-ketoacyl synthase, N-terminal, IPR014031:Beta-ketoacyl synthase, C-terminal, IPR016039:Thiolase-like, IPR017568:3-oxoacyl-[acyl-carrier-protein] synthase 2, IPR020841:Polyketide synthase, beta-ketoacyl synthase domain" CG12170 27-Aug-18 DroID_v2018_08 Drer\oxsm Scer\CEM1 Cele\F10G8.9 Xtro\oxsm Mmus\Oxsm Hsap\OXSM viable FBgn0264898 lncRNA:CR44089 - http://flybase.org/reports/FBgn0264898 non_protein_coding_gene - - - CR44089 - CR44089 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033734 CG8520 - http://flybase.org/reports/FBgn0033734 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR005654 sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - "CG8520, FBgn 33734" "IPR005654:ATPase, AFG1-like, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG8520 27-Aug-18 DroID_v2018_08 "Drer\lace1b, Drer\lace1a" Scer\AFG1 Cele\C30F12.2 Xtro\lace1 Mmus\Lace1 Hsap\LACE1 "viable,fertile" FBgn0053470 CG33470 - http://flybase.org/reports/FBgn0053470 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33470 - CG33470 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033861 CG12464 - http://flybase.org/reports/FBgn0033861 protein_coding_gene - - mitochondrial respiratory chain complex I ; GO:0005747 | inferred from electronic annotation with InterPro:IPR026193 CG12464 IPR026193:NADH-ubiquinone oxidoreductase flavoprotein 3 CG12464 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0025576 M285 M285 http://flybase.org/reports/FBgn0025576 - gene molecular_function ; GO:0003674 | no biological data available Notch signaling pathway ; GO:0007219 | inferred from genetic interaction with N nervous system development ; GO:0007399 | inferred from mutant phenotype sensory organ development ; GO:0007423 | inferred from genetic interaction with N imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from genetic interaction with N cellular_component ; GO:0005575 | no biological data available M285 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0084025 CG41464 - http://flybase.org/reports/FBgn0084025 protein_coding_gene - - - CG41464 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0044506 BS\RTase BS element RTase http://flybase.org/reports/FBgn0044506 transposable_element_gene - - cellular_component ; GO:0005575 | no biological data available "RT, Bs ORF2, BS\RTase, RTase" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036838 CG3808 - http://flybase.org/reports/FBgn0036838 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 RNA methyltransferase activity ; GO:0008173 | inferred from electronic annotation with InterPro:IPR010280 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity RNA processing ; GO:0006396 | inferred from electronic annotation with InterPro:IPR010280 - "cg3808, CG3808" "IPR000504:RNA recognition motif domain, IPR030391:RNA methyltransferase TrmA, conserved site, IPR030390:RNA methyltransferase TrmA, active site, IPR010280:(Uracil-5)-methyltransferase family, IPR034262:TRMT2A, RNA recognition motif, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG3808 27-Aug-18 DroID_v2018_08 "Drer\trmt2b, Drer\trmt2a" Scer\TRM2 Cele\H24K24.4 "Xtro\trmt2b, Xtro\trmt2a" "Mmus\Trmt2a, Mmus\Trmt2b" "Hsap\TRMT2A, Hsap\TRMT2B" "viable,fertile" FBgn0058257 CR40257 - http://flybase.org/reports/FBgn0058257 non_protein_coding_gene - - - CR40257 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065817 l(2)SH0377 lethal (2) SH0377 http://flybase.org/reports/FBgn0065817 gene - - - "l(2)SH0377, l(2)SH2 0377" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0052791 DIP-alpha Dpr-interacting protein alpha http://flybase.org/reports/FBgn0052791 protein_coding_gene - synapse organization ; GO:0050808 | inferred from expression pattern neuron projection membrane ; GO:0032589 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from sequence model "CG32791, CG13020, CG13019, 32791, DIP-alpha" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set" CG32791 27-Aug-18 DroID_v2018_08 "Drer\mxra8b, Drer\zgc:110372, Drer\lsamp, Drer\si:zfos-1011f11.1, Drer\gpa33, Drer\vsig8a, Drer\si:dkey-65b12.12, Drer\mxra8a, Drer\cxcr3.1, Drer\si:ch211-9d9.7, Drer\si:ch211-215e19.3, Drer\f11r.1, Drer\jam3b, Drer\vsig8b, Drer\f11r.2, Drer\pigrl4.2, Drer\ntm, Drer\jam3a, Drer\jam2a, Drer\LOC100151468, Drer\si:dkey-250k15.10, Drer\negr1, Drer\opcml, Drer\igsf11, Drer\cxadr, Drer\jam2b, Drer\esamb, Drer\esama, Drer\zgc:153073" - "Cele\rig-5, Cele\zig-4" "Xtro\ntm, Xtro\negr1, Xtro\lsamp" "Mmus\Esam, Mmus\Vsig8, Mmus\Igsf11, Mmus\Iglon5, Mmus\Jam3, Mmus\Vsig2, Mmus\Vsir, Mmus\Opcml, Mmus\F11r, Mmus\Clmp, Mmus\Negr1, Mmus\Ntm, Mmus\Mxra8, Mmus\Gm1123, Mmus\Hepacam2, Mmus\Jam2, Mmus\Vsig1, Mmus\Igsf5, Mmus\Lsamp, Mmus\Gpa33, Mmus\Cxadr" "Hsap\GPA33, Hsap\CLMP, Hsap\NEGR1, Hsap\IGSF11, Hsap\JAM3, Hsap\IGLON5, Hsap\F11R, Hsap\CXADR, Hsap\MXRA8, Hsap\VSIG1, Hsap\VSIG8, Hsap\OPCML, Hsap\NTM, Hsap\C1orf204, Hsap\LSAMP, Hsap\VSIG2, Hsap\JAM2, Hsap\ESAM, Hsap\C10orf54, Hsap\IGSF5" "visible,partially lethal - majority die,some die during pupal stage,lethal" "chaeta,supernumerary,trichogen cell" FBgn0060840 l(3)S049508b lethal (3) S049508b http://flybase.org/reports/FBgn0060840 gene - - - "0495/08, l(3)S049508b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0050371 CG30371 - http://flybase.org/reports/FBgn0050371 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP80, CG2280, CG30371" "IPR000859:CUB domain, IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site" CG30371 27-Aug-18 DroID_v2018_08 Drer\f10 - "Cele\F25E5.3, Cele\svh-1, Cele\try-5, Cele\try-9, Cele\T21E12.3" - "Mmus\Tmprss7, Mmus\Tmprss6, Mmus\St14" "Hsap\TMPRSS6, Hsap\TMPRSS7, Hsap\F10, Hsap\ST14" "viable,visible" "antenna,leg,ectopic" FBgn0025472 qkr58E-5 quaking related 58E-5 http://flybase.org/reports/FBgn0025472 - gene - - - "qrk58E-5, qkr58E-5" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267739 asRNA:CR46070 - http://flybase.org/reports/FBgn0267739 non_protein_coding_gene - - - "CR46070, Mgn3671" - CR46070 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051754 His-Psi:CR31754 His-Psi:CR31754 http://flybase.org/reports/FBgn0051754 pseudogene_attribute - - - "CR31754, His-Psi:CR31754" - CR31754 27-Aug-18 DroID_v2018_08 - - - - - - DRSC22051 IE 1.765175641 -3.517577589 -1.389565049 -5.118172072 0.626504918 0.964516608 FBgn0263841 CG43702 - http://flybase.org/reports/FBgn0263841 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43702 - CG43702 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0029895 CG14441 - http://flybase.org/reports/FBgn0029895 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG14441 "IPR012934:Zinc finger, AD-type, IPR019400:Peptidase C65, otubain, IPR013087:Zinc finger C2H2-type, IPR015943:WD40/YVTN repeat-like-containing domain" CG14441 27-Aug-18 DroID_v2018_08 Drer\srcap Scer\SWR1 Cele\ssl-1 - Mmus\Srcap Hsap\SRCAP "viable,fertile" FBgn0037005 CG5078 - http://flybase.org/reports/FBgn0037005 protein_coding_gene transporter activity ; GO:0005215 | inferred from biological aspect of ancestor with PANTHER:PTN001921112 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN001921112 "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005829, InterPro:IPR011701" CG5078 "IPR001958:Tetracycline resistance protein TetA/multidrug resistance protein MdtG, IPR005829:Sugar transporter, conserved site, IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG5078 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-5g14.1, Drer\hiat1b, Drer\si:ch211-262i1.4, Drer\hiat1a, Drer\LOC557306, Drer\zgc:174356, Drer\slc46a3, Drer\si:ch211-87m7.2" Scer\YJL163C "Cele\T25D3.4, Cele\Y71G12B.25" "Xtro\mfsd14a, Xtro\mfsd14b" "Mmus\Slc46a3, Mmus\Mfsd14b, Mmus\Slc46a1, Mmus\Mfsd14a" "Hsap\MFSD14A, Hsap\MFSD14B, Hsap\SLC46A1, Hsap\SLC46A3" "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0000683 flrdF flight reduced F http://flybase.org/reports/FBgn0000683 - gene molecular_function ; GO:0003674 | no biological data available flight behavior ; GO:0007629 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available flrdF - - 27-Aug-18 DroID_v2018_08 - - - - - - "jumping defective,flightless" FBgn0065115 l(3)SH160 lethal (3) SH160 http://flybase.org/reports/FBgn0065115 gene - - - "l(3)SH160, l(2)SH3 160" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0065493 l(2)SH1228 lethal (2) SH1228 http://flybase.org/reports/FBgn0065493 gene - - - "l(2)SH1228, l(2)SH2 1228" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0267802 lncRNA:CR46127 - http://flybase.org/reports/FBgn0267802 non_protein_coding_gene - - - CR46127 - CR46127 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0029789 PGAP1 Post-GPI attachment to proteins 1 http://flybase.org/reports/FBgn0029789 protein_coding_gene phosphoric ester hydrolase activity ; GO:0042578 | inferred from sequence or structural similarity with UniProtKB:Q765A7 nuclease activity ; GO:0004518 | inferred from sequence or structural similarity with UniProtKB:Q765A7 myo-inositol transport ; GO:0015798 | inferred from sequence or structural similarity with UniProtKB:Q765A7 endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with UniProtKB:Q765A7 "CG3160, PGAP1" "IPR012908:GPI inositol-deacylase PGAP1-like, IPR029058:Alpha/Beta hydrolase fold" CG3160 27-Aug-18 DroID_v2018_08 Drer\pgap1 Scer\BST1 "Cele\her-1, Cele\T19B10.8, Cele\lips-9, Cele\nhr-49" - "Mmus\Pgap1, Mmus\Epas1" "Hsap\PGAP1, Hsap\C2orf66" "viable,body color defective" mesothoracic tergum FBgn0031187 Usp2 Ubiquitin specific protease 2 http://flybase.org/reports/FBgn0031187 protein_coding_gene Lys48-specific deubiquitinase activity ; GO:1990380 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with imd thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from sequence or structural similarity with HGNC:12631 proteasome binding ; GO:0070628 | inferred from physical interaction with Rpt6 ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from electronic annotation with InterPro:IPR018200 negative regulation of innate immune response ; GO:0045824 | inferred from mutant phenotype negative regulation of defense response to bacterium ; GO:1900425 | inferred from mutant phenotype protein deubiquitination ; GO:0016579 | inferred from mutant phenotype protein K48-linked deubiquitination ; GO:0071108 | inferred from direct assay protein deubiquitination ; GO:0016579 | inferred from sequence or structural similarity with HGNC:12631 negative regulation of antimicrobial peptide production ; GO:0002785 | inferred from mutant phenotype positive regulation of proteasomal protein catabolic process ; GO:1901800 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG14619, Usp2, Q9VR54, dUsp2" "IPR001394:Peptidase C19, ubiquitin carboxyl-terminal hydrolase, IPR018200:Ubiquitin specific protease, conserved site, IPR028889:Ubiquitin specific protease domain" CG14619 27-Aug-18 DroID_v2018_08 "Drer\usp4, Drer\usp43b, Drer\usp8, Drer\usp2b, Drer\usp21, Drer\usp32, Drer\usp11, Drer\usp2a" "Scer\UBP5, Scer\UBP7, Scer\UBP11, Scer\DOA4, Scer\UBP12, Scer\UBP8" "Cele\F07A11.4, Cele\usp-3, Cele\H34C03.2, Cele\usp-33, Cele\cyk-3, Cele\usp-50" "Xtro\usp21, Xtro\usp15, Xtro\usp8, Xtro\usp37, Xtro\usp2" "Mmus\Usp15, Mmus\Usp4, Mmus\Usp26, Mmus\Usp27x, Mmus\Usp43, Mmus\Usp22, Mmus\Usp2, Mmus\Usp11, Mmus\Usp8, Mmus\Usp3, Mmus\Usp32, Mmus\Usp37, Mmus\Usp29, Mmus\Usp21, Mmus\Usp50" "Hsap\USP4, Hsap\USP50, Hsap\USP37, Hsap\USP11, Hsap\USP3, Hsap\USP2, Hsap\USP21, Hsap\USP10, Hsap\USP8, Hsap\USP27X, Hsap\USP22, Hsap\USP43, Hsap\USP29, Hsap\USP32, Hsap\USP26" "lethal,recessive,body color defective,partially lethal - majority die,some die during pupal stage,lethal - all die before end of pupal stage,viable,locomotor behavior defective,short lived" "mesothoracic tergum,prepupa" FBgn0000365 cpw canopy wing http://flybase.org/reports/FBgn0000365 - gene - - - cpw - - 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,partially lethal - majority die,visible,recessive,viable,male,reduced" "wing,wing vein,eye,ocellar bristle,thorax,adult thorax,macrochaeta,microchaeta,head bristle" FBgn0031268 cold coiled http://flybase.org/reports/FBgn0031268 protein_coding_gene - "wound healing ; GO:0042060 | inferred from mutant phenotype maintenance of permeability of blood-brain barrier ; GO:0035633 | inferred from direct assay establishment of blood-brain barrier ; GO:0060856 | inferred from direct assay septate junction assembly ; GO:0019991 | inferred from direct assay septate junction assembly ; GO:0019991 | inferred from mutant phenotype regulation of tube size, open tracheal system ; GO:0035151 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay "CG2813, cold, cg2813, leaky4" - CG2813 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-134a4.1, Drer\si:ch211-134a4.5, Drer\negaly6, Drer\LOC100535423, Drer\si:ch211-134a4.2, Drer\si:dkeyp-80c12.8, Drer\si:dkey-102g19.3" - - - "Mmus\Pinlyp, Mmus\2210407C18Rik, Mmus\1810065E05Rik, Mmus\4930504O13Rik, Mmus\Gm12253, Mmus\Lypd8" "Hsap\PINLYP, Hsap\LYPD8" "lethal,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval dorsal trunk,presumptive embryonic/larval tracheal system,subperineurial glial cell,trichogen cell" FBgn0000333 cmd carminoid http://flybase.org/reports/FBgn0000333 - gene - - - cmd - - 27-Aug-18 DroID_v2018_08 - - - - - - eye color defective pigment cell FBgn0025870 C141 C141 http://flybase.org/reports/FBgn0025870 - gene - adult walking behavior ; GO:0007628 | traceable author statement - C141 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0069929 CG41122 - http://flybase.org/reports/FBgn0069929 protein_coding_gene - - - CG41122 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0014932 anon-87Ea anon-87Ea http://flybase.org/reports/FBgn0014932 - gene - - - "A, anon-87Ea" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0003139 PpV Protein phosphatase V http://flybase.org/reports/FBgn0003139 - protein_coding_gene "hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR004843, InterPro:IPR006186 protein serine/threonine phosphatase activity ; GO:0004722 | non-traceable author statement protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence model" mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype protein dephosphorylation ; GO:0006470 | non-traceable author statement G1/S transition of mitotic cell cycle ; GO:0000082 | inferred from genetic interaction with SGD:S000002205 protein dephosphorylation ; GO:0006470 | inferred from sequence model cytoplasm ; GO:0005737 | inferred from direct assay "DmPpV-6A, CG12217, PPV, PPPV6A, PPV 6A, PpV, Ppv, dPP6, PP6, PpV[[C]]" "IPR004843:Calcineurin-like phosphoesterase domain, ApaH type, IPR006186:Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase, IPR029052:Metallo-dependent phosphatase-like" CG12217 27-Aug-18 DroID_v2018_08 "Drer\zgc:56064, Drer\ppp4ca, Drer\ppp6c, Drer\ppp2ca, Drer\ppp4cb, Drer\ppp2cb" "Scer\YNL217W, Scer\SIT4, Scer\PPH22, Scer\PPH3, Scer\PPH21" "Cele\pph-6, Cele\pph-4.1, Cele\pph-4.2" "Xtro\ppp4c, Xtro\ppp6c, Xtro\ppp2ca, Xtro\ppp2cb" "Mmus\Ppp2ca, Mmus\Ppp4c, Mmus\Ppp6c, Mmus\Ppp2cb" "Hsap\PPP2CA, Hsap\PPP6C, Hsap\PPP2CB" " embryonic stage | stage 5 , embryonic stage -- adult stage , embryonic stage | stage 4 " organism

" embryonic stage | stage 4 , embryonic stage | stage 5 " organism

"visible,viable" "wing,trichogen cell" FBgn0052745 CR32745 - http://flybase.org/reports/FBgn0052745 pseudogene_attribute - - - "CG32745, CR32745" - CR32745 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037513 pyd3 pyd3 http://flybase.org/reports/FBgn0037513 protein_coding_gene beta-ureidopropionase activity ; GO:0003837 | inferred from direct assay 'de novo' pyrimidine nucleobase biosynthetic process ; GO:0006207 | inferred from genetic interaction with r pyrimidine nucleobase catabolic process ; GO:0006208 | inferred by curator from GO:0003837 - "CG3027, pyd3, betaASase, betaAS" IPR003010:Carbon-nitrogen hydrolase CG3027 27-Aug-18 DroID_v2018_08 Drer\upb1 - Cele\upb-1 Xtro\upb1 Mmus\Upb1 Hsap\UPB1 "viable,fertile" FBgn0263133 mEFG1 mitochondrial translation elongation factor G 1 http://flybase.org/reports/FBgn0263133 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR000795, InterPro:IPR004161, InterPro:IPR004540, InterPro:IPR005225, InterPro:IPR005517 translation elongation factor activity ; GO:0003746 | inferred from biological aspect of ancestor with PANTHER:PTN002462392 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with UniProtKB:Q96RP9 translation elongation factor activity ; GO:0003746 | inferred from sequence or structural similarity with UniProtKB:Q96RP9 GTPase activity ; GO:0003924 | inferred from biological aspect of ancestor with PANTHER:PTN002462392" mitochondrial translational elongation ; GO:0070125 | inferred from sequence or structural similarity with UniProtKB:Q96RP9 mitochondrial translational elongation ; GO:0070125 | inferred from biological aspect of ancestor with PANTHER:PTN000563009 nucleus ; GO:0005634 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay "CG4567, dEF-G1, GFM1, G, l(2)27Ea, B, l(2)27Cb, ico, mEFG1" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR014721:Ribosomal protein S5 domain 2-type fold, subgroup, IPR009022:Elongation factor G, III-V domain, IPR009000:Translation protein, beta-barrel domain, IPR005517:Translation elongation factor EFG/EF2, domain IV, IPR005225:Small GTP-binding protein domain, IPR004540:Translation elongation factor EFG/EF2, IPR004161:Translation elongation factor EFTu-like, domain 2, IPR000795:Transcription factor, GTP-binding domain, IPR000640:Translation elongation factor EFG, V domain, IPR020568:Ribosomal protein S5 domain 2-type fold, IPR031157:Tr-type G domain, conserved site" CG4567 27-Aug-18 DroID_v2018_08 "Drer\gfm1, Drer\gfm2" "Scer\MEF1, Scer\MEF2" "Cele\gfm-1, Cele\Y119D3B.14, Cele\F58G1.8" "Xtro\gfm1, Xtro\gfm2" "Mmus\Gfm2, Mmus\Gfm1" "Hsap\GFM1, Hsap\GFM2" FBgn0050108 CG30108 - http://flybase.org/reports/FBgn0050108 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available mitochondrial intermembrane space ; GO:0005758 | inferred from biological aspect of ancestor with PANTHER:PTN000481815 CG30108 IPR007918:Mitochondrial distribution/morphology family 35/apoptosis CG30108 27-Aug-18 DroID_v2018_08 Drer\triap1 Scer\MDM35 Cele\T09A5.7 Xtro\triap1 Mmus\Triap1 Hsap\TRIAP1 "viable,fertile" FBgn0262114 RanBPM Ran-binding protein M http://flybase.org/reports/FBgn0262114 protein_coding_gene Ran GTPase binding ; GO:0008536 | inferred from sequence or structural similarity with HGNC:13727 larval feeding behavior ; GO:0030536 | inferred from mutant phenotype germ-line stem-cell niche homeostasis ; GO:0060250 | inferred from mutant phenotype dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype ovarian follicle cell-cell adhesion ; GO:0007299 | inferred from mutant phenotype JAK-STAT cascade ; GO:0007259 | inferred from mutant phenotype cytoskeleton organization ; GO:0007010 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay membrane ; GO:0016020 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "RanBPM, CG42236, CG11763, l(2)k05201" "IPR024964:CTLH/CRA C-terminal to LisH motif domain, IPR013320:Concanavalin A-like lectin/glucanase domain, IPR001870:B30.2/SPRY domain, IPR006594:LIS1 homology motif, IPR013144:CRA domain, IPR006595:CTLH, C-terminal LisH motif, IPR003877:SPRY domain" CG42236 27-Aug-18 DroID_v2018_08 "Drer\ranbp10, Drer\spryd3, Drer\ranbp9" "Scer\SSH4, Scer\EAR1, Scer\VID30" "Cele\tag-304, Cele\Y54E5A.7" "Xtro\ranbp9, Xtro\spryd3" "Mmus\Ranbp9, Mmus\Ranbp10, Mmus\Spryd3" "Hsap\SPRYD3, Hsap\RANBP10, Hsap\RANBP9" FBgn0026165 schmalspur schmalspur http://flybase.org/reports/FBgn0026165 - gene molecular_function ; GO:0003674 | no biological data available central nervous system development ; GO:0007417 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "sur, schmalspur" - - 27-Aug-18 DroID_v2018_08 - - - - - - "commissure,midline glial cell,presumptive embryonic/larval central nervous system,longitudinal connective,presumptive embryonic/larval peripheral nervous system,sensory neuron,motor neuron" FBgn0266651 lncRNA:CR45158 - http://flybase.org/reports/FBgn0266651 non_protein_coding_gene - - - CR45158 - CR45158 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266220 lncRNA:CR44915 - http://flybase.org/reports/FBgn0266220 non_protein_coding_gene - - - CR44915 - CR44915 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0025107 Brg-P9 Brg-P9 http://flybase.org/reports/FBgn0025107 - gene - - - Brg-P9 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0069334 UY4766 UY4766 http://flybase.org/reports/FBgn0069334 gene - - - UY4766 - - 27-Aug-18 DroID_v2018_08 - - - - - - neuroanatomy defective "mushroom body & axon7B,Kenyon cell,mushroom body gamma-lobe" FBgn0262372 mir-3 mir-3 stem loop http://flybase.org/reports/FBgn0262372 miRNA_gene - - - "mir-3, 3, miR-3, CR42890, CR33037" - CR42890 27-Aug-18 DroID_v2018_08 - - - - - - embryonic stage | 0-12 hr "viable,lethal,lethal - all die before end of pupal stage,some die during pupal stage" wing FBgn0039558 BCAS2 BCAS2 http://flybase.org/reports/FBgn0039558 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "mRNA processing ; GO:0006397 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013" Prp19 complex ; GO:0000974 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay "CG4980, BCAS2, dBCAS2" IPR008409:Pre-mRNA-splicing factor SPF27 CG4980 27-Aug-18 DroID_v2018_08 Drer\bcas2 - Cele\T12A2.7 Xtro\bcas2 Mmus\Bcas2 Hsap\BCAS2 "viable,visible,body color defective,increased cell death,lethal" "trichogen cell,mesothoracic tergum,wing,scutellum,chaeta,wing disc,posterior compartment" FBgn0058165 CG40165 - http://flybase.org/reports/FBgn0058165 protein_coding_gene - - - CG40165 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259345 EP-990 - http://flybase.org/reports/FBgn0259345 gene - - - EP-990 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing vein,wing margin,chaeta,ectopic" FBgn0044389 Scim5 Sensitized chromosome inheritance modifier 5 http://flybase.org/reports/FBgn0044389 gene - female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype - Scim5 - - 27-Aug-18 DroID_v2018_08 - - - - - - "meiotic cell cycle defective,dominant" FBgn0022344 CG10340 - http://flybase.org/reports/FBgn0022344 - protein_coding_gene - mitochondrial proton-transporting ATP synthase complex assembly ; GO:0033615 | inferred from biological aspect of ancestor with PANTHER:PTN000319591 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000319591 "anon2A5, anon-EST:fe2A5, CG10340" IPR010591:ATP11 CG10340 27-Aug-18 DroID_v2018_08 Drer\atpaf1 Scer\ATP11 - Xtro\atpaf1 Mmus\Atpaf1 Hsap\ATPAF1 "viable,fertile" FBgn0085786 CR41501 - http://flybase.org/reports/FBgn0085786 pseudogene_attribute - - - CR41501 - CR41501 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037879 scpr-C SCP-containing protein C http://flybase.org/reports/FBgn0037879 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available extracellular region ; GO:0005576 | inferred from sequence model "SCPR-C, CG5106, BEST:CK01680, scpr-C, Scpr-C, scp-C, cg5106" "IPR001283:Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR014044:CAP domain, IPR034763:Venom allergen 3, insect" CG5106 27-Aug-18 DroID_v2018_08 "Drer\r3hdml, Drer\glipr2, Drer\glipr2l, Drer\glipr1b, Drer\LOC101883528, Drer\crispld1b, Drer\LOC100536500, Drer\pi15b, Drer\pi15a, Drer\crispld1a, Drer\crispld2" "Scer\PRY2, Scer\PRY3, Scer\PRY1" "Cele\scl-6, Cele\scl-21, Cele\scl-2, Cele\scl-7, Cele\scl-14, Cele\scl-1, Cele\scl-20, Cele\scl-9, Cele\scl-19, Cele\scl-12, Cele\scl-10, Cele\scl-11, Cele\scl-18, Cele\scl-15, Cele\vap-2, Cele\scl-23, Cele\scl-8, Cele\scl-17, Cele\scl-3, Cele\scl-5, Cele\scl-13" "Xtro\MGC108118, Xtro\glipr2, Xtro\crispld2, Xtro\pi15, Xtro\crisp1, Xtro\crisp2, Xtro\r3hdml, Xtro\crisp3" "Mmus\Glipr1, Mmus\Glipr1l1, Mmus\Glipr1l2, Mmus\Pi16, Mmus\Pi15, Mmus\R3hdml, Mmus\Crispld2, Mmus\Crisp1, Mmus\Glipr2, Mmus\Crispld1, Mmus\Crisp4, Mmus\Clec18a, Mmus\Crisp2, Mmus\Crisp3" "Hsap\CRISPLD2, Hsap\GLIPR2, Hsap\CRISP1, Hsap\R3HDML, Hsap\GLIPR1L1, Hsap\CRISPLD1, Hsap\GLIPR1, Hsap\CLEC18A, Hsap\CLEC18B, Hsap\PI16, Hsap\CRISP2, Hsap\GLIPR1L2, Hsap\CLEC18C, Hsap\PI15" viable FBgn0034863 SkpF SKP1-related F http://flybase.org/reports/FBgn0034863 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence or structural similarity with SGD:S000002736 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from sequence or structural similarity with SGD:S000002736 SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence or structural similarity with SGD:S000002736 "CG12227, Skp, SkpF, skpF" "IPR011333:SKP1/BTB/POZ domain, IPR001232:S-phase kinase-associated protein 1-like, IPR016072:SKP1 component, dimerisation, IPR016073:SKP1 component, POZ domain, IPR016897:S-phase kinase-associated protein 1" CG12227 27-Aug-18 DroID_v2018_08 Drer\skp1 "Scer\SKP1, Scer\ELC1" "Cele\skr-6, Cele\skr-18, Cele\skr-20, Cele\skr-15, Cele\skr-10, Cele\skr-9, Cele\skr-21, Cele\skr-13, Cele\skr-16, Cele\skr-19, Cele\skr-7, Cele\skr-5, Cele\skr-17, Cele\skr-3, Cele\skr-14, Cele\skr-1, Cele\skr-8, Cele\skr-4, Cele\skr-12, Cele\skr-2" Xtro\skp1 Mmus\Skp1a Hsap\SKP1 FBgn0063388 snoRNA:U27:54Ea snoRNA:U27:54Ea http://flybase.org/reports/FBgn0063388 snoRNA_gene - - - "U27snoRNA, CR32892, snoRNA:U27:54Ea" - CR32892 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005725 l(1)TK135 lethal (1) TK135 http://flybase.org/reports/FBgn0005725 - gene - - - "l135, l(1)TK135" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0259566 GG01373 - http://flybase.org/reports/FBgn0259566 gene - - - GG01373 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "antennal segment,wing" FBgn0004754 l(3)89Bg lethal (3) 89Bg http://flybase.org/reports/FBgn0004754 - gene - - - l(3)89Bg - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0021928 l(2)k11118 lethal (2) k11118 http://flybase.org/reports/FBgn0021928 - gene - - - l(2)k11118 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0265496 lncRNA:CR44365 - http://flybase.org/reports/FBgn0265496 non_protein_coding_gene - - - "CR44365, lincRNA.303" - CR44365 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065476 l(2)SH1305 lethal (2) SH1305 http://flybase.org/reports/FBgn0065476 gene - - - "l(2)SH1305, l(2)SH2 1305" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0032361 CG6488 - http://flybase.org/reports/FBgn0032361 protein_coding_gene molecular_function ; GO:0003674 | no biological data available intra-Golgi vesicle-mediated transport ; GO:0006891 | inferred from biological aspect of ancestor with PANTHER:PTN000480807 intra-Golgi vesicle-mediated transport ; GO:0006891 | inferred from sequence or structural similarity with SGD:S000004536 Golgi transport complex ; GO:0017119 | inferred from direct assay "CG6488, Cog8" "IPR007255:Conserved oligomeric Golgi complex subunit 8, IPR016632:Conserved oligomeric Golgi complex subunit 8, Metazoal and Viridiplantae, IPR016159:Cullin repeat-like-containing domain" CG6488 27-Aug-18 DroID_v2018_08 Drer\cog8 Scer\COG8 Cele\cogc-8 Xtro\cog8 Mmus\Cog8 Hsap\COG8 "viable,fertile" FBgn0060673 l(3)S077801 lethal (3) S077801 http://flybase.org/reports/FBgn0060673 gene - - - "0778/01, l(3)S077801" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0061167 l(1)20BC lethal (1) 20BC http://flybase.org/reports/FBgn0061167 gene - - - l(1)20BC - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0002475 l(3)SG30 lethal (3) SG30 http://flybase.org/reports/FBgn0002475 - gene - - - "SG30, l(3)SG30" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" eye-antennal disc FBgn0085453 CG34424 - http://flybase.org/reports/FBgn0085453 protein_coding_gene 5-formyltetrahydrofolate cyclo-ligase activity ; GO:0030272 | inferred from sequence or structural similarity with UniProtKB:P80405 5-formyltetrahydrofolate cyclo-ligase activity ; GO:0030272 | inferred from biological aspect of ancestor with PANTHER:PTN000601268 tetrahydrofolate interconversion ; GO:0035999 | inferred from biological aspect of ancestor with PANTHER:PTN000601268 folic acid-containing compound biosynthetic process ; GO:0009396 | inferred from biological aspect of ancestor with PANTHER:PTN000601268 cytosol ; GO:0005829 | inferred from sequence or structural similarity with UniProtKB:P80405 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000601269 "CG34424, anon-WO0118547.139, CG11079" IPR002698:5-formyltetrahydrofolate cyclo-ligase CG34424 27-Aug-18 DroID_v2018_08 Drer\mthfs Scer\FAU1 Cele\Y106G6E.4 Xtro\mthfs "Mmus\Mthfs, Mmus\Mthfsl" "Hsap\ST20-MTHFS, Hsap\MTHFS" viable FBgn0065505 l(2)SH1197 lethal (2) SH1197 http://flybase.org/reports/FBgn0065505 gene - - - "l(2)SH1197, l(2)SH2 1197" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0021901 l(2)k12408 lethal (2) k12408 http://flybase.org/reports/FBgn0021901 - gene - - - l(2)k12408 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0030052 CG12065 - http://flybase.org/reports/FBgn0030052 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR000845 nucleoside metabolic process ; GO:0009116 | inferred from electronic annotation with InterPro:IPR000845 lateral inhibition ; GO:0046331 | inferred from mutant phenotype - CG12065 "IPR011991:Winged helix-turn-helix DNA-binding domain, IPR000845:Nucleoside phosphorylase domain" CG12065 27-Aug-18 DroID_v2018_08 - - Cele\H14E04.2 - - - "viable,fertile,visible" "chaeta,supernumerary" FBgn0264282 Su(Mir)3C2-1 - http://flybase.org/reports/FBgn0264282 gene - - - Su(Mir)3C2-1 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0053100 eIF4EHP eukaryotic translation initiation factor 4E homologous protein http://flybase.org/reports/FBgn0053100 protein_coding_gene translation initiation factor activity ; GO:0003743 | inferred from electronic annotation with InterPro:IPR001040 protein binding ; GO:0005515 | inferred from physical interaction with brat translation repressor activity ; GO:0030371 | inferred from genetic interaction with bcd RNA 7-methylguanosine cap binding ; GO:0000340 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with bcd eukaryotic initiation factor 4G binding ; GO:0031370 | NOT inferred from direct assay translational initiation ; GO:0006413 | inferred from electronic annotation with InterPro:IPR001040 inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype positive regulation of ecdysteroid biosynthetic process ; GO:0045998 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype negative regulation of translation ; GO:0017148 | inferred from genetic interaction with bcd imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR001040 "4EHP, eIF4E-8, CG33100, d4EHP, CG10716, CT30033, 4E-HP, eIF4EHP" "IPR001040:Translation Initiation factor eIF- 4e, IPR023398:Translation Initiation factor eIF- 4e-like" CG33100 27-Aug-18 DroID_v2018_08 "Drer\eif4e2rs1, Drer\eif4e2" Scer\CDC33 Cele\ife-4 Xtro\eif4e2 Mmus\Eif4e2 Hsap\EIF4E2 "viable,fertile,behavior defective,recessive,partially lethal - majority die,maternal effect,some die during embryonic stage,lethal,neuroanatomy defective,visible,some die during pupal stage" "embryonic head segment,maternal effect,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0265625 CG44433 - http://flybase.org/reports/FBgn0265625 protein_coding_gene - - - "CG15086, CG44433" - CG44433 27-Aug-18 DroID_v2018_08 - - Cele\Y32B12B.4 - - - FBgn0260807 EP3-980 - http://flybase.org/reports/FBgn0260807 gene - - - EP3-980 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004719 ads all discs small http://flybase.org/reports/FBgn0004719 - gene - - - "l(3)ry100, l(3)ds16, ads" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0267617 asRNA:CR45955 - http://flybase.org/reports/FBgn0267617 non_protein_coding_gene - - - CR45955 - CR45955 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0023213 eIF4G1 eukaryotic translation initiation factor 4G1 http://flybase.org/reports/FBgn0023213 - protein_coding_gene "translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity with HGNC:3296,SGD:S000003394 eukaryotic initiation factor 4E binding ; GO:0008190 | inferred from physical interaction with eIF4E1 RNA 7-methylguanosine cap binding ; GO:0000340 | inferred from direct assay eukaryotic initiation factor 4E binding ; GO:0008190 | inferred from physical interaction with eIF4E1 inferred from physical interaction with eIF4E4 inferred from physical interaction with eIF4E5 inferred from physical interaction with eIF4E7 inferred from physical interaction with eIF4E3 RNA binding ; GO:0003723 | inferred from direct assay" "mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs spermatid differentiation ; GO:0048515 | inferred from mutant phenotype translation ; GO:0006412 | inferred from direct assay G1/S transition of mitotic cell cycle ; GO:0000082 | inferred from mutant phenotype male germ-line cyst formation ; GO:0048136 | inferred from mutant phenotype spermatocyte division ; GO:0048137 | inferred from genetic interaction with eIF4G2 mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype translational initiation ; GO:0006413 | inferred from sequence or structural similarity with HGNC:3296,SGD:S000003394 translational initiation ; GO:0006413 | inferred from sequence or structural similarity" eukaryotic translation initiation factor 4F complex ; GO:0016281 | inferred from direct assay cytosol ; GO:0005829 | inferred from sequence or structural similarity cytosol ; GO:0005829 | inferred from direct assay eukaryotic translation initiation factor 4F complex ; GO:0016281 | inferred from sequence or structural similarity "eIF4G, eIF4g, CG10811, Eif4G, p200, deIF4G, eIF-4G, EIF4G, eIF4G1" "IPR003307:W2 domain, IPR003890:MIF4G-like, type 3, IPR003891:Initiation factor eIF-4 gamma, MA3, IPR016024:Armadillo-type fold" CG10811 27-Aug-18 DroID_v2018_08 "Drer\eif4g3a, Drer\eif4g1a, Drer\eif4g1b, Drer\eif4g2b, Drer\eif4g3b, Drer\eif4g2a" "Scer\TIF4631, Scer\TIF4632" Cele\ifg-1 "Xtro\eif4g3, Xtro\LOC100145496" "Mmus\Eif4g3, Mmus\Eif4g2, Mmus\Eif4g1" "Hsap\EIF4G3, Hsap\EIF4G1, Hsap\EIF4G2" lethal DRSC17218 IE 0.876038645 -2.069641687 -2.405192068 -1.40025058 -1.066382831 -0.527779547 FBgn0022265 l(2)k00611 lethal (2) k00611 http://flybase.org/reports/FBgn0022265 - gene - - - l(2)k00611 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0000025 acj1 abnormal chemosensory jump 1 http://flybase.org/reports/FBgn0000025 - gene molecular_function ; GO:0003674 | no biological data available chemosensory jump behavior ; GO:0007636 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available acj1 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265212 fs(2)Z2-147 - http://flybase.org/reports/FBgn0265212 gene - - - fs(2)Z2-147 - - 27-Aug-18 DroID_v2018_08 - - - - - - female sterile FBgn0010140 l(2)DTS486 lethal (2) DTS486 http://flybase.org/reports/FBgn0010140 - gene - - - "DTS486, l(2)DTS486" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,dominant,partially,heat sensitive,female sterile" FBgn0031183 CG14621 - http://flybase.org/reports/FBgn0031183 protein_coding_gene - biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG14621, Slc35e1, lincRNA.1043" IPR004853:Sugar phosphate transporter domain CG14621 27-Aug-18 DroID_v2018_08 "Drer\slc35e3, Drer\slc35e4, Drer\slc35e1, Drer\si:ch73-236j9.2" "Scer\YJL193W, Scer\SLY41" - "Xtro\siah3, Xtro\slc35e1" "Mmus\Slc35e4, Mmus\Slc35e2, Mmus\Slc35e1, Mmus\Slc35e3" "Hsap\SLC35E2B, Hsap\SLC35E3, Hsap\SLC35E1, Hsap\SLC35E4, Hsap\SLC35E2" viable FBgn0005025 dumpyoidy dumpyoidy http://flybase.org/reports/FBgn0005025 - gene - - - "dpy, dumpyoidy" - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive" wing FBgn0031971 Sirup Starvation-upregulated protein http://flybase.org/reports/FBgn0031971 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon-EST:Posey12, BcDNA:GH18422, dSdhaf4, CG7224, Sirup, Sdhaf4" IPR012875:Protein of unknown function DUF1674 CG7224 27-Aug-18 DroID_v2018_08 Drer\sdhaf4 Scer\SDH8 Cele\W02D3.12 Xtro\sdhaf4 Mmus\Sdhaf4 Hsap\SDHAF4 "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0047095 CG33939 - http://flybase.org/reports/FBgn0047095 protein_coding_gene - - - "CR33939, BcDNA:RE54004, CG33939, pncr004:X" - CG33939 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0015539 scs special chromatin structure http://flybase.org/reports/FBgn0015539 - insulator - - - "scs, SCS" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0028544 CG16884 - http://flybase.org/reports/FBgn0028544 protein_coding_gene - wing disc development ; GO:0035220 | inferred from mutant phenotype - "BG:DS00180.3, CG16884, vajk-3" - CG16884 27-Aug-18 DroID_v2018_08 - - Cele\T26C11.2 - Mmus\Ggn "Hsap\ZNF512B, Hsap\TPRX1, Hsap\GGN" "visible,size defective" "wing vein L3,wing vein L4,anterior crossvein,ectopic,posterior crossvein,wing,posterior,wing cell" FBgn0060837 l(3)S049610 lethal (3) S049610 http://flybase.org/reports/FBgn0060837 gene - - - "0496/10, l(3)S049610" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0032669 CG15155 - http://flybase.org/reports/FBgn0032669 protein_coding_gene "transferase activity, transferring acyl groups other than amino-acyl groups ; GO:0016747 | inferred from electronic annotation with InterPro:IPR013653" - - "CT35055, CG15155" "IPR016181:Acyl-CoA N-acyltransferase, IPR013653:FR47-like" CG15155 27-Aug-18 DroID_v2018_08 "Drer\si:ch73-106k19.2, Drer\si:dkey-76k16.5, Drer\si:dkey-76k16.6" - Cele\ZK185.3 - - Hsap\GLYATL3 viable FBgn0050402 CG30402 - http://flybase.org/reports/FBgn0050402 protein_coding_gene - - - CG30402 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030310 PGRP-SA Peptidoglycan recognition protein SA http://flybase.org/reports/FBgn0030310 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR006619 peptidoglycan binding ; GO:0042834 | non-traceable author statement peptidoglycan receptor activity ; GO:0016019 | inferred from sequence or structural similarity with UniProtKB:O76537 peptidoglycan receptor activity ; GO:0016019 | non-traceable author statement peptidoglycan binding ; GO:0042834 | inferred from direct assay peptidoglycan binding ; GO:0042834 | traceable author statement signaling pattern recognition receptor activity ; GO:0008329 | traceable author statement peptidoglycan binding ; GO:0042834 | non-traceable author statement inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with GNBP1 N-acetylmuramoyl-L-alanine amidase activity ; GO:0008745 | NOT inferred from key residues muramyl dipeptide binding ; GO:0032500 | inferred from direct assay peptidoglycan receptor activity ; GO:0016019 | traceable author statement innate immune response ; GO:0045087 | inferred from electronic annotation with InterPro:IPR017331 defense response to Gram-positive bacterium ; GO:0050830 | inferred from genetic interaction with GNBP1 positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria ; GO:0006965 | inferred from mutant phenotype innate immune response ; GO:0045087 | non-traceable author statement peptidoglycan catabolic process ; GO:0009253 | NOT inferred from key residues defense response to Gram-positive bacterium ; GO:0050830 | inferred from direct assay peptidoglycan catabolic process ; GO:0009253 | non-traceable author statement immune response ; GO:0006955 | inferred from sequence or structural similarity with UniProtKB:O76537 response to peptidoglycan ; GO:0032494 | inferred from mutant phenotype regulation of Toll signaling pathway ; GO:0008592 | traceable author statement Toll signaling pathway ; GO:0008063 | traceable author statement positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria ; GO:0006965 | traceable author statement immune response ; GO:0006955 | traceable author statement defense response to Gram-positive bacterium ; GO:0050830 | traceable author statement innate immune response ; GO:0045087 | traceable author statement extracellular region ; GO:0005576 | inferred from sequence or structural similarity extracellular region ; GO:0005576 | inferred from direct assay "seml, SEMMELWEIS, CG11709, BcDNA:AT30827, PGRP-SA, Dm PGRP-SA, SA, pgrp-sa" "IPR002502:N-acetylmuramoyl-L-alanine amidase domain, IPR006619:Peptidoglycan recognition protein family domain, metazoa/bacteria, IPR015510:Peptidoglycan recognition protein, IPR017331:Peptidoglycan recognition protein, PGRP-S" CG11709 27-Aug-18 DroID_v2018_08 "Drer\pglyrp6, Drer\pglyrp2, Drer\pglyrp5" - - "Xtro\pglyrp1, Xtro\pglyrp2, Xtro\pglyrp1" "Mmus\Pglyrp3, Mmus\Pglyrp4, Mmus\Pglyrp1, Mmus\Pglyrp2" "Hsap\PGLYRP1, Hsap\PGLYRP3, Hsap\PGLYRP4, Hsap\PGLYRP2" "immune response defective,viable" FBgn0040398 CG14629 - http://flybase.org/reports/FBgn0040398 protein_coding_gene - - - "EG:103E12.2, CG14629" IPR009832:Protein of unknown function DUF1397 CG14629 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033041 Or42a Odorant receptor 42a http://flybase.org/reports/FBgn0033041 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from mutant phenotype olfactory behavior ; GO:0042048 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 "Or42a, 42a, DOR117, 41E.2, CG17250, Or42A, OR42a" "IPR004117:Olfactory receptor, insect" CG17250 27-Aug-18 DroID_v2018_08 - - - - - - "smell perception defective,viable,fertile" adult olfactory receptor neuron Or42a FBgn0000306 che cherub http://flybase.org/reports/FBgn0000306 - gene - - - che - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive,male sterile,sterile,female sterile" wing FBgn0024631 l(2)k14316 lethal (2) k14316 http://flybase.org/reports/FBgn0024631 - gene - - - "143/16, l(2)k14316" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0001278 J Jammed http://flybase.org/reports/FBgn0001278 - gene - - - J - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,heat sensitive,viable,lethal,recessive,reduced" "wing,alula" FBgn0015584 Acp53Ea Accessory gland protein 53Ea http://flybase.org/reports/FBgn0015584 FBgn0063350 protein_coding_gene - multicellular organism reproduction ; GO:0032504 | inferred from expression pattern sperm competition ; GO:0046692 | traceable author statement extracellular space ; GO:0005615 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence model "Acp53E, BcDNA:AT09943, CG8622, Acp53Ea, ACP53EA" IPR009392:Drosophila ACP53EA CG8622 27-Aug-18 DroID_v2018_08 - - - - - - adult stage | male " male accessory gland

, male accessory gland main cell

" viable FBgn0042165 CG18845 - http://flybase.org/reports/FBgn0042165 protein_coding_gene - - - CG18845 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0022257 l(2)k01006 lethal (2) k01006 http://flybase.org/reports/FBgn0022257 - gene - - - l(2)k01006 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0039453 CG6403 - http://flybase.org/reports/FBgn0039453 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG6403 IPR002557:Chitin binding domain CG6403 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0037120 CG11247 - http://flybase.org/reports/FBgn0037120 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 regulation of cell cycle ; GO:0051726 | inferred from direct assay - CG11247 "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG11247 27-Aug-18 DroID_v2018_08 "Drer\zgc:113452, Drer\znf410, Drer\LOC100535506, Drer\si:dkeyp-2e4.8, Drer\zgc:174623, Drer\zgc:171422, Drer\si:dkey-253d23.2" "Scer\ZAP1, Scer\PZF1" "Cele\hinf-1, Cele\C27A12.2, Cele\ztf-23, Cele\sem-4, Cele\eor-1, Cele\fezf-1, Cele\blmp-1, Cele\Y5F2A.4, Cele\lst-5, Cele\Y55F3AM.14, Cele\let-391" Xtro\znf410 "Mmus\Zfp3, Mmus\Zfp639, Mmus\Zfp410, Mmus\Zfp354b, Mmus\Zfp473, Mmus\Zfp354a" "Hsap\ZNF99, Hsap\ZSCAN20, Hsap\ZNF133, Hsap\ZNF639, Hsap\ZNF410, Hsap\ZNF564" "viable,fertile" DRSC26558 K -0.214621344 0.430984818 0.101049218 -0.17493128 0.429641584 -1.529961902 FBgn0039955 CG41099 - http://flybase.org/reports/FBgn0039955 protein_coding_gene metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR000306 embryonic morphogenesis ; GO:0048598 | inferred from mutant phenotype endocytosis ; GO:0006897 | inferred from mutant phenotype epithelial cell morphogenesis ; GO:0003382 | inferred from mutant phenotype vacuole ; GO:0005773 | inferred from direct assay "CG41099, CG17419, CG17416, GM10035, BEST:GM10035" "IPR000210:BTB/POZ domain, IPR000306:FYVE zinc finger, IPR002110:Ankyrin repeat, IPR011011:Zinc finger, FYVE/PHD-type, IPR011333:SKP1/BTB/POZ domain, IPR017455:Zinc finger, FYVE-related, IPR020683:Ankyrin repeat-containing domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG41099 27-Aug-18 DroID_v2018_08 "Drer\ankrd55, Drer\si:ch211-11n16.2, Drer\zak, Drer\ankfy1, Drer\hgs, Drer\ripk3, Drer\ank2a, Drer\dstyk, Drer\ripk4, Drer\zfyve19, Drer\pbk, Drer\ripk2, Drer\ank3b, Drer\LOC405768, Drer\map3k10, Drer\map3k9, Drer\zfyve1, Drer\lrrk2, Drer\mos, Drer\ripk1l, Drer\ank3a, Drer\ank1b, Drer\si:ch211-120p12.3" "Scer\YGL242C, Scer\MGA2, Scer\YCR051W, Scer\VPS27, Scer\SPT23" "Cele\T28D6.4, Cele\F22G12.4, Cele\dhhc-13" "Xtro\lrrk2, Xtro\ank3, Xtro\zfyve19, Xtro\ankk1, Xtro\lrrk1, Xtro\ripk1, Xtro\ank2, Xtro\ank1, Xtro\dstyk, Xtro\hgs, Xtro\mlkl, Xtro\pbk, Xtro\map3k9, Xtro\LOC100490493, Xtro\ankfy1, Xtro\zak, Xtro\zfyve1, Xtro\ripk4, Xtro\map3k7, Xtro\map3k10" "Mmus\Zfyve1, Mmus\Mos, Mmus\Ankrd55, Mmus\Map3k11, Mmus\Ank1, Mmus\BC021891, Mmus\Ank2, Mmus\Map3k9, Mmus\Ripk1, Mmus\Mlkl, Mmus\Pbk, Mmus\Hgs, Mmus\Map3k10, Mmus\Lrrk1, Mmus\Ripk2, Mmus\Zfyve19, Mmus\Ripk4, Mmus\Zak, Mmus\Map3k7, Mmus\Ank3, Mmus\Dstyk, Mmus\Lrrk2, Mmus\Ankfy1, Mmus\Ripk3" "Hsap\PBK, Hsap\ZFYVE19, Hsap\ANK3, Hsap\RIPK4, Hsap\RIPK2, Hsap\ZFYVE1, Hsap\LRRK1, Hsap\MAP3K20, Hsap\ANKRD55, Hsap\HGS, Hsap\LRRK2, Hsap\MAP3K9, Hsap\DSTYK, Hsap\MAP3K11, Hsap\ANK1, Hsap\ANKFY1, Hsap\RIPK3, Hsap\MLKL, Hsap\MOS, Hsap\RIPK1, Hsap\MAP3K21, Hsap\MAP3K10, Hsap\MAP3K7, Hsap\ANK2" viable FBgn0266736 asRNA:CR45209 - http://flybase.org/reports/FBgn0266736 non_protein_coding_gene - - - CR45209 - CR45209 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262402 mir-311 mir-311 stem loop http://flybase.org/reports/FBgn0262402 miRNA_gene - response to nicotine ; GO:0035094 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype head involution ; GO:0008258 | inferred from mutant phenotype cellular response to nitric oxide ; GO:0071732 | inferred from direct assay - "mir-311, miR-311, 311, Dme-miR-311, CR42943, CR33615, dme-mir-311, dme-miR-311, mIR-311" - CR42943 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible,lethal - all die before end of P-stage,some die during pharate adult stage,lethal,partially lethal - majority die" "wing,wing vein,1st posterior cell" FBgn0030786 mRpL22 mitochondrial ribosomal protein L22 http://flybase.org/reports/FBgn0030786 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with EMBL:AA772054 structural constituent of ribosome ; GO:0003735 | traceable author statement mitochondrial translation ; GO:0032543 | traceable author statement translation ; GO:0006412 | inferred from sequence or structural similarity with EMBL:AA772054 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q3SZX5 mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with EMBL:AA772054 mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with UniProtKB:Q9NWU5 "CG4742, L22, mRpL22" "IPR001063:Ribosomal protein L22/L17, IPR005727:Ribosomal protein L22, bacterial/chloroplast-type" CG4742 27-Aug-18 DroID_v2018_08 Drer\mrpl22 "Scer\RPL17B, Scer\MRPL22, Scer\RPL17A" Cele\mrpl-22 Xtro\mrpl22 Mmus\Mrpl22 Hsap\MRPL22 "viable,visible" "trichogen cell,mesothoracic tergum" DRSC19915 K -0.906735727 -0.25072513 -0.178543384 -0.409460697 -1.94043949 -0.252965782 FBgn0069402 KH3 KH3 http://flybase.org/reports/FBgn0069402 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available KH3 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001728 l(1)ESHS49 lethal (1) ESHS49 http://flybase.org/reports/FBgn0001728 - gene - - - l(1)ESHS49 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0025814 Mgstl Microsomal glutathione S-transferase-like http://flybase.org/reports/FBgn0025814 "FBgn0031147, FBgn0047002, FBgn0061409" protein_coding_gene glutathione transferase activity ; GO:0004364 | inferred from sequence or structural similarity with UniProtKB:P10620 glutathione transferase activity ; GO:0004364 | inferred from sequence or structural similarity with HGNC:7061 - mitochondrial outer membrane ; GO:0005741 | inferred from sequence or structural similarity with UniProtKB:P10620 intracellular membrane-bounded organelle ; GO:0043231 | inferred from sequence or structural similarity with HGNC:7061 lipid particle ; GO:0005811 | inferred from direct assay intracellular membrane-bounded organelle ; GO:0043231 | inferred from sequence or structural similarity with UniProtKB:P10620 "Mgst1, CG1742, BcDNA:RH59553, BcDNA:RE10696, Mgstl" "IPR001129:Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein, IPR023352:Membrane associated eicosanoid/glutathione metabolism-like domain" CG1742 27-Aug-18 DroID_v2018_08 "Drer\mgst1.2, Drer\mgst1.1, Drer\ptges" - - "Xtro\ptges, Xtro\mgst1" "Mmus\Mgst1, Mmus\Ptges" "Hsap\PTGES, Hsap\MGST1" "partially lethal - majority die,visible,viable,fertile,short lived" "eye,arista,tarsal segment,macrochaeta,wing,scutellum" FBgn0063356 CR30370 - http://flybase.org/reports/FBgn0063356 non_protein_coding_gene - - - "BcDNA:AT05157, CR30370" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0023083 fray frayed http://flybase.org/reports/FBgn0023083 "FBgn0010922, FBgn0026023" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441, InterPro:IPR024678 receptor signaling protein serine/threonine kinase activity ; GO:0004702 | inferred from biological aspect of ancestor with PANTHER:PTN000684825 receptor signaling protein serine/threonine kinase activity ; GO:0004702 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from mutant phenotype" "chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from mutant phenotype establishment of blood-nerve barrier ; GO:0008065 | inferred from mutant phenotype axon ensheathment ; GO:0008366 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement protein localization to cell cortex ; GO:0072697 | inferred from genetic interaction with mira, Lkb1 protein phosphorylation ; GO:0006468 | inferred from mutant phenotype protein autophosphorylation ; GO:0046777 | inferred from direct assay" cytoplasm ; GO:0005737 | inferred from direct assay "STE20-like/SPAK, CG7693, l(3)07551, lag, 4624, fray, Fray, dSTRAD, dOSR1, Dosr1" "IPR000719:Protein kinase domain, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR024678:Serine/threonine-protein kinase OSR1/WNK, CCT domain" CG7693 27-Aug-18 DroID_v2018_08 "Drer\oxsr1b, Drer\stk39, Drer\oxsr1a, Drer\wu:fj77h11" Scer\STE20 "Cele\hpo-11, Cele\gck-3" "Xtro\strada, Xtro\stk39, Xtro\stradb" "Mmus\Oxsr1, Mmus\Stk39, Mmus\Stradb, Mmus\Strada" "Hsap\STK39, Hsap\STRADA, Hsap\OXSR1, Hsap\STRADB" " embryonic stage | stage >=15 , embryonic stage | stage >=12 , embryonic stage | early , embryonic stage | stage 17 " " abdominal ventral oblique muscle 6

, larval hindgut

, exit glial cell

, larval midgut

, larval proventriculus

, dorsal neurohemal organ

" "visible,viable,fertile,lethal,recessive,maternal effect,lethal - all die before end of larval stage,some die during larval stage" "wing vein,ectopic,wing vein L4,embryonic/first instar larval cuticle,maternal effect,embryonic/larval peripheral nervous system,trichogen cell,posterior wing margin" DRSC16950 K 0.194590866 0.670186911 1.095502173 0.002877787 1.959282807 0.23182972 FBgn0040692 CG13938 - http://flybase.org/reports/FBgn0040692 protein_coding_gene - - - CG13938 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039912 CG11260 - http://flybase.org/reports/FBgn0039912 protein_coding_gene - - - CG11260 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0019784 l(1)218 lethal (1) 218 http://flybase.org/reports/FBgn0019784 - gene - - - l(1)218 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,partially,recessive" FBgn0038392 CG17631 - http://flybase.org/reports/FBgn0038392 protein_coding_gene - - - CG17631 - - 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0033899 CG13016 - http://flybase.org/reports/FBgn0033899 protein_coding_gene - - - CG13016 IPR019397:Uncharacterised protein family TMEM39 CG13016 27-Aug-18 DroID_v2018_08 "Drer\tmem39b, Drer\tmem39a" - Cele\D1007.5 "Xtro\tmem39b, Xtro\tmem39a" "Mmus\Tmem39b, Mmus\Tmem39a" "Hsap\TMEM39A, Hsap\TMEM39B" viable FBgn0001730 l(1)ESHS51 lethal (1) ESHS51 http://flybase.org/reports/FBgn0001730 - gene - - - l(1)ESHS51 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0083960 CG34124 - http://flybase.org/reports/FBgn0083960 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cilium-dependent cell motility ; GO:0060285 | inferred from biological aspect of ancestor with PANTHER:PTN000346980 cellular_component ; GO:0005575 | no biological data available "CG31652, CG34124" "IPR011047:Quinoprotein alcohol dehydrogenase-like superfamily, IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG34124 27-Aug-18 DroID_v2018_08 Drer\si:dkey-1f12.3 - - "Xtro\cfap44, Xtro\eml6" "Mmus\Eml5, Mmus\Cfap44, Mmus\Eml6" "Hsap\CFAP44, Hsap\EML6, Hsap\EML5" "viable,fertile" FBgn0065472 l(2)SH1328 lethal (2) SH1328 http://flybase.org/reports/FBgn0065472 gene - - - "l(2)SH1328, l(2)SH2 1328" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0031347 CG10869 - http://flybase.org/reports/FBgn0031347 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG10869 IPR032013:Protein of unknown function DUF4795 CG10869 27-Aug-18 DroID_v2018_08 - - - - "Mmus\4930562C15Rik, Mmus\Qrich2" "Hsap\QRICH2, Hsap\C16orf96" viable FBgn0041007 CG17541 - http://flybase.org/reports/FBgn0041007 protein_coding_gene - - - CG17541 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260350 GSd302 - http://flybase.org/reports/FBgn0260350 gene - - - GSd302 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve,segmental nerve" FBgn0038722 Nup58 Nucleoporin 58kD http://flybase.org/reports/FBgn0038722 protein_coding_gene nucleocytoplasmic transporter activity ; GO:0005487 | inferred from biological aspect of ancestor with PANTHER:PTN001412288 nucleocytoplasmic transporter activity ; GO:0005487 | inferred from sequence or structural similarity with UniProtKB:P70581 nuclear localization sequence binding ; GO:0008139 | inferred from biological aspect of ancestor with PANTHER:PTN001412288 protein import into nucleus ; GO:0006606 | inferred from biological aspect of ancestor with PANTHER:PTN001412288 neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype nucleocytoplasmic transport ; GO:0006913 | inferred from sequence or structural similarity with UniProtKB:P70581 nuclear pore ; GO:0005643 | inferred from biological aspect of ancestor with PANTHER:PTN001412288 nuclear pore ; GO:0005643 | inferred from sequence or structural similarity with UniProtKB:P70581 "CG7360, Nup58, Dm NUP58, RE52572p" "IPR024945:Spt5 C-terminal domain, IPR024882:Nucleoporin p58/p45" CG7360 27-Aug-18 DroID_v2018_08 "Drer\nup58, Drer\nup98, Drer\nup62l" "Scer\NUP100, Scer\NSP1, Scer\NUP49, Scer\NUP145, Scer\NUP116" "Cele\npp-11, Cele\npp-10" Xtro\nup58 "Mmus\Nup98, Mmus\Nup62, Mmus\Nup62cl, Mmus\Nupl1" "Hsap\NUP98, Hsap\NUP58, Hsap\NUP62" "sterile,partially lethal,viable" FBgn0037985 ssp5 short spindle 5 http://flybase.org/reports/FBgn0037985 protein_coding_gene - - - "anon-WO0140519.127, ssp5, CG14735, Ssp5, Tes59" "IPR031936:Domain of unknown function DUF4771, IPR031935:Domain of unknown function DUF4770" CG14735 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0036490 CG6888 - http://flybase.org/reports/FBgn0036490 protein_coding_gene thioredoxin peroxidase activity ; GO:0008379 | inferred from sequence or structural similarity with HGNC:9352 "cell redox homeostasis ; GO:0045454 | inferred from electronic annotation with InterPro:IPR013766 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000866, InterPro:IPR019479 hydrogen peroxide catabolic process ; GO:0042744 | inferred from sequence or structural similarity with HGNC:9352 cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:9352 extracellular exosome ; GO:0070062 | inferred from sequence or structural similarity with HGNC:9352 "BcDNA:AT16346, CG6888, 6888" "IPR000866:Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant, IPR012336:Thioredoxin-like fold, IPR019479:Peroxiredoxin, C-terminal, IPR024706:Peroxiredoxin, AhpC-type, IPR013766:Thioredoxin domain" CG6888 27-Aug-18 DroID_v2018_08 "Drer\prdx4, Drer\prdx3, Drer\prdx6, Drer\prdx1, Drer\prdx2" "Scer\PRX1, Scer\TSA1, Scer\TSA2" "Cele\prdx-2, Cele\prdx-6, Cele\prdx-3" "Xtro\prdx2, Xtro\prdx3, Xtro\prdx1, Xtro\prdx4" "Mmus\Prdx3, Mmus\Prdx1, Mmus\Prdx2, Mmus\Prdx6, Mmus\Prdx4" "Hsap\PRDX1, Hsap\PRDX4, Hsap\PRDX6, Hsap\PRDX3, Hsap\PRDX2" "viable,fertile" FBgn0005601 yemG2.8 yema gene 2.8 http://flybase.org/reports/FBgn0005601 FBgn0004042 gene - - - "yG2.8/2.6, yG2.8, yG2.6, yT2.8, yT2.6, yemG2.8" - - 27-Aug-18 DroID_v2018_08 - - - - - - " adult stage && oogenesis stage , embryonic stage | stage <=8 , embryonic stage | stage <6 , embryonic stage | stage <= 8 " " ovary

, organism

" FBgn0027560 Tps1 Trehalose-6-phosphate synthase 1 http://flybase.org/reports/FBgn0027560 "FBgn0001908, FBgn0022028" protein_coding_gene trehalose-phosphatase activity ; GO:0004805 | inferred from direct assay trehalose metabolism in response to stress ; GO:0070413 | inferred from biological aspect of ancestor with PANTHER:PTN000082159 photoreceptor cell maintenance ; GO:0045494 | inferred from mutant phenotype trehalose biosynthetic process ; GO:0005992 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000082159 lipid particle ; GO:0005811 | inferred from direct assay "BcDNA:GH08860, tps1, TreS, CG4104, dtps1, TPS, jf5, l(2)k08903, l(2)jf5, l(2)jf4, l(2)24Ea, Tps1, CG4104 PA, dTps1, 19920676" "IPR001830:Glycosyl transferase, family 20, IPR003337:Trehalose-phosphatase, IPR006379:HAD-superfamily hydrolase, subfamily IIB, IPR023214:HAD-like domain" CG4104 27-Aug-18 DroID_v2018_08 - "Scer\TPS2, Scer\TPS3, Scer\TSL1, Scer\TPS1" "Cele\tps-1, Cele\tps-2, Cele\gob-1" - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,visible,lethal - all die before end of pupal stage,heat sensitive,some die during pupal stage" "eye,ommatidium" FBgn0002995 om ommatidia http://flybase.org/reports/FBgn0002995 - gene - - - om - - 27-Aug-18 DroID_v2018_08 - - - - - - "eye,ommatidium" FBgn0030799 CG4872 - http://flybase.org/reports/FBgn0030799 protein_coding_gene "transcription corepressor activity ; GO:0003714 | inferred from sequence or structural similarity with HGNC:2418 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor ; GO:0016639 | inferred from biological aspect of ancestor with PANTHER:PTN000352164 hormone binding ; GO:0042562 | inferred from biological aspect of ancestor with PANTHER:PTN001013561" negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from sequence or structural similarity with HGNC:2418 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:2418 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000352164 CG4872 "IPR003462:Ornithine cyclodeaminase/mu-crystallin, IPR016040:NAD(P)-binding domain, IPR023401:Ornithine cyclodeaminase, N-terminal" CG4872 27-Aug-18 DroID_v2018_08 Drer\crym Scer\YGL159W - Xtro\crym Mmus\Crym Hsap\CRYM FBgn0015857 anon-14Aa anon-14Aa http://flybase.org/reports/FBgn0015857 - gene - - - "t6, anon-14Aa" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005704 l(1)TK107 lethal (1) TK107 http://flybase.org/reports/FBgn0005704 - gene - - - "l107, l(1)TK107" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" "eye,lamina" FBgn0019701 l(2)42Bb lethal (2) 42Bb http://flybase.org/reports/FBgn0019701 - gene - - - "l(2)6G1, 6G1, l(2)42Bb" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0045473 Gr85a Gustatory receptor 85a http://flybase.org/reports/FBgn0045473 protein_coding_gene taste receptor activity ; GO:0008527 | non-traceable author statement sensory perception of taste ; GO:0050909 | inferred from electronic annotation with InterPro:IPR013604 sensory perception of taste ; GO:0050909 | non-traceable author statement integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 integral component of membrane ; GO:0016021 | non-traceable author statement "CG31405, Gr85a" IPR013604:7TM chemoreceptor CG31405 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0267426 CR45779 - http://flybase.org/reports/FBgn0267426 pseudogene_attribute - - - "CR45779, Mst77Y" - CR45779 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0010849 l(3)04837 lethal (3) 04837 http://flybase.org/reports/FBgn0010849 - gene molecular_function ; GO:0003674 | no biological data available segmentation ; GO:0035282 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available l(3)04837 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,maternal effect,poor" "embryonic/first instar larval cuticle,maternal effect,segment" FBgn0060753 l(3)S064318 lethal (3) S064318 http://flybase.org/reports/FBgn0060753 gene - - - "0643/18, l(3)S064318" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0001596 l(1)carot14 lethal (1) carot14 http://flybase.org/reports/FBgn0001596 - gene - - - "l(1)TW5, l(1)carot14" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,visible,female sterile" "wing,adult abdomen" FBgn0030613 Rab3-GEF Rab3 GDP-GTP exchange factor http://flybase.org/reports/FBgn0030613 protein_coding_gene Rab guanyl-nucleotide exchange factor activity ; GO:0017112 | inferred from biological aspect of ancestor with PANTHER:PTN000988808 Rab guanyl-nucleotide exchange factor activity ; GO:0017112 | inferred from sequence or structural similarity with UniProtKB:Q8WXG6 regulation of extrinsic apoptotic signaling pathway via death domain receptors ; GO:1902041 | inferred from sequence or structural similarity with UniProtKB:Q8WXG6 activation of MAPK activity ; GO:0000187 | inferred from sequence or structural similarity with UniProtKB:Q8WXG6 cytoskeletal matrix organization at active zone ; GO:0048789 | inferred from mutant phenotype regulation of Rab protein signal transduction ; GO:0032483 | inferred from sequence or structural similarity with HGNC:6766 neurotransmitter secretion ; GO:0007269 | non-traceable author statement vesicle-mediated transport ; GO:0016192 | non-traceable author statement regulation of cell cycle ; GO:0051726 | inferred from sequence or structural similarity with UniProtKB:Q8WXG6 neuromuscular junction of somatic muscle ; GO:0098527 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with UniProtKB:Q8WXG6 neuronal cell body ; GO:0043025 | inferred from direct assay synaptic vesicle ; GO:0008021 | non-traceable author statement terminal bouton ; GO:0043195 | inferred from direct assay "CG5627, BEST:GH21304, anon-EST:Posey246, rab3-GEF, Rab3-GEF" "IPR001194:DENN domain, IPR005112:dDENN domain, IPR005113:uDENN domain" CG5627 27-Aug-18 DroID_v2018_08 Drer\madd - "Cele\aex-3, Cele\mtm-5" Xtro\madd Mmus\Madd Hsap\MADD "viable,fertile" FBgn0034010 CG8157 - http://flybase.org/reports/FBgn0034010 protein_coding_gene - - - "BcDNA:RE07473, CG8157" - CG8157 27-Aug-18 DroID_v2018_08 - - Cele\fipr-21 - - - viable FBgn0264909 lncRNA:CR44100 - http://flybase.org/reports/FBgn0264909 non_protein_coding_gene - - - CR44100 - CR44100 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004359 T48 Transcript 48 http://flybase.org/reports/FBgn0004359 - protein_coding_gene - ventral furrow formation ; GO:0007370 | inferred from mutant phenotype inferred from genetic interaction with cta apical plasma membrane ; GO:0016324 | inferred from direct assay "48, t48, anon-97D, Ubx-t48, CG5507, T48" IPR009030:Growth factor receptor cysteine-rich domain CG5507 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" ventral furrow FBgn0031695 Cyp4ac3 Cyp4ac3 http://flybase.org/reports/FBgn0031695 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "CG14031, 4ac3, Cyp4ac3" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG14031 27-Aug-18 DroID_v2018_08 "Drer\cyp3a65, Drer\cyp26c1, Drer\LOC100329425, Drer\cyp4f3, Drer\cyp19a1a, Drer\cyp4v8, Drer\cyp4v7, Drer\cyp46a1.1, Drer\cyp46a1.3, Drer\cyp26b1, Drer\cyp19a1b, Drer\cyp46a1.2, Drer\cyp3c4, Drer\cyp3c3, Drer\cyp26a1, Drer\cyp3c1, Drer\cyp46a1.4, Drer\cyp3c2, Drer\cyp20a1, Drer\cyp4t8" "Scer\ERG5, Scer\DIT2" "Cele\cyp-37B1, Cele\cyp-29A4, Cele\cyp-13A10, Cele\cyp-13A7, Cele\cyp-13A11, Cele\cyp-13A5, Cele\cyp-25A1, Cele\cyp-13A8, Cele\cyp-29A2, Cele\cyp-25A2, Cele\cyp-32A1, Cele\cyp-42A1, Cele\cyp-31A3, Cele\cyp-13A1, Cele\cyp-25A4, Cele\cyp-14A1, Cele\cyp-37A1, Cele\cyp-31A5, Cele\cyp-13A3, Cele\cyp-25A3, Cele\cyp-13A12, Cele\cyp-31A2, Cele\cyp-29A3, Cele\cyp-32B1, Cele\cyp-13A4" "Xtro\cyp26a1, Xtro\cyp4f2, Xtro\cyp20a1, Xtro\cyp4v2, Xtro\cyp26b1, Xtro\LOC100487918, Xtro\LOC100488227, Xtro\cyp4f22, Xtro\mgc108213, Xtro\cyp19a1, Xtro\cyp26c1, Xtro\cyp4b1.2, Xtro\cyp4b1" "Mmus\Cyp4f14, Mmus\Cyp3a57, Mmus\Cyp4a29, Mmus\Cyp20a1, Mmus\Cyp4a30b, Mmus\Cyp19a1, Mmus\Cyp3a59, Mmus\Cyp3a41a, Mmus\Cyp4f18, Mmus\Cyp26b1, Mmus\Cyp3a25, Mmus\Cyp46a1, Mmus\Cyp4a32, Mmus\Cyp26c1, Mmus\Cyp4v3, Mmus\Cyp4f40, Mmus\Cyp4f39, Mmus\Cyp4a14, Mmus\Cyp4b1, Mmus\Cyp4a12a, Mmus\Cyp4x1, Mmus\Cyp4f13, Mmus\Cyp3a41b, Mmus\Cyp3a16, Mmus\Cyp4a31, Mmus\Cyp3a13, Mmus\Cyp4f37, Mmus\Cyp3a44, Mmus\Cyp4f15, Mmus\Cyp26a1, Mmus\Cyp4a12b, Mmus\Cyp4f17, Mmus\Cyp3a11, Mmus\Cyp4f16, Mmus\Cyp4a10" "Hsap\CYP4F2, Hsap\CYP3A43, Hsap\CYP4F12, Hsap\CYP4F22, Hsap\CYP26B1, Hsap\CYP4Z1, Hsap\CYP19A1, Hsap\CYP4A22, Hsap\CYP46A1, Hsap\CYP20A1, Hsap\CYP26C1, Hsap\CYP4F11, Hsap\CYP3A4, Hsap\CYP4B1, Hsap\CYP3A7, Hsap\CYP3A5, Hsap\CYP4X1, Hsap\CYP26A1, Hsap\CYP4A11, Hsap\CYP4V2, Hsap\CYP4F8, Hsap\CYP4F3" "lethal - all die before end of pupal stage,some die during pupal stage,viable" FBgn0025158 ms(2)A1 ms(2)A1 http://flybase.org/reports/FBgn0025158 - gene - - - ms(2)A1 - - 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,recessive" FBgn0065161 l(3)SH043 lethal (3) SH043 http://flybase.org/reports/FBgn0065161 gene - - - "l(3)SH043, l(2)SH3 043" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0060661 l(3)S082414a lethal (3) S082414a http://flybase.org/reports/FBgn0060661 gene - - - "0824/14, l(3)S082414a" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,partially lethal - majority die,recessive" FBgn0016810 l(1)L11 lethal (1) L11 http://flybase.org/reports/FBgn0016810 - gene - - - "l(1)L11, L11" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0001339 l(1)1Bg lethal (1) 1Bg http://flybase.org/reports/FBgn0001339 - gene - - - "l(1)Bg, l(1)1Bg" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0051065 ppk31 pickpocket 31 http://flybase.org/reports/FBgn0051065 protein_coding_gene sodium channel activity ; GO:0005272 | inferred from sequence or structural similarity with MGI:MGI:101782 sodium ion transport ; GO:0006814 | inferred from sequence or structural similarity with MGI:MGI:101782 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with MGI:MGI:101782 "CG31065, ppk31" "IPR001873:Epithelial sodium channel, IPR017896:4Fe-4S ferredoxin-type, iron-sulphur binding domain" CG31065 27-Aug-18 DroID_v2018_08 "Drer\asic4a, Drer\asic1b, Drer\asic2, Drer\asic1a, Drer\asic1c, Drer\asic4b" - "Cele\acd-1, Cele\del-7, Cele\delm-1, Cele\acd-5, Cele\delm-2, Cele\acd-4, Cele\flr-1, Cele\acd-2" "Xtro\scnn1g, Xtro\scnn1b, Xtro\asic4, Xtro\scnn1a, Xtro\scnn1d, Xtro\asic5, Xtro\asic1" "Mmus\Asic2, Mmus\Scnn1b, Mmus\Asic1, Mmus\Asic5, Mmus\Asic3, Mmus\Scnn1a, Mmus\Asic4, Mmus\Scnn1g" "Hsap\SCNN1D, Hsap\ASIC3, Hsap\ASIC1, Hsap\ASIC2, Hsap\SCNN1B, Hsap\SCNN1G, Hsap\SCNN1A, Hsap\ASIC5, Hsap\ASIC4" "viable,lethal" DRSC13811 I 1.689848384 0.073480041 1.317502813 0.452099998 -0.243868111 0.013649685 FBgn0039799 CG15543 - http://flybase.org/reports/FBgn0039799 protein_coding_gene nucleobase-containing compound kinase activity ; GO:0019205 | inferred from electronic annotation with InterPro:IPR000850 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000850 nucleobase-containing compound metabolic process ; GO:0006139 | inferred from electronic annotation with InterPro:IPR000850 - CG15543 "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR000850:Adenylate kinase/UMP-CMP kinase" CG15543 27-Aug-18 DroID_v2018_08 "Drer\ak3, Drer\ak4, Drer\ak2, Drer\ak8, Drer\si:ch211-199m3.4, Drer\ak7b, Drer\ak7a" "Scer\ADK2, Scer\ADK1" - "Xtro\ak8, Xtro\ak9, Xtro\ak7, Xtro\ak3, Xtro\ak4, Xtro\ak2" "Mmus\Ak7, Mmus\Ak9, Mmus\Ak8, Mmus\Ak4, Mmus\Ak2, Mmus\Ak3" "Hsap\AK9, Hsap\AK7, Hsap\AK8, Hsap\AK3, Hsap\AK4, Hsap\AK2" viable FBgn0069446 E(br)420 E(br)420 http://flybase.org/reports/FBgn0069446 gene - - - E(br)420 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0029139 P(3)98DF P(3)98DF http://flybase.org/reports/FBgn0029139 gene - - - P(3)98DF - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267137 lncRNA:CR45577 - http://flybase.org/reports/FBgn0267137 non_protein_coding_gene - - - CR45577 - CR45577 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060984 l(3)S028218b lethal (3) S028218b http://flybase.org/reports/FBgn0060984 gene - - - "0282/18, l(3)S028218b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0040246 anon-57Bb anon-57Bb http://flybase.org/reports/FBgn0040246 gene - - - anon-57Bb - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030307 CG33235 - http://flybase.org/reports/FBgn0030307 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG15192, CG33235" - CG33235 27-Aug-18 DroID_v2018_08 Drer\aim1b - - - - - "viable,partially lethal - majority die,some die during pupal stage" FBgn0015425 l(1)1CDb lethal (1) 1CDb http://flybase.org/reports/FBgn0015425 - gene - - - l(1)1CDb - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0001879 l(1)YD23b lethal (1) YD23b http://flybase.org/reports/FBgn0001879 - gene - - - "l(1)YD23, l(1)YD23b" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0016053 pgc polar granule component http://flybase.org/reports/FBgn0016053 FBgn0034719 protein_coding_gene - "pole cell migration ; GO:0007280 | inferred from mutant phenotype pole cell development ; GO:0007277 | inferred from mutant phenotype germ cell migration ; GO:0008354 | traceable author statement negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay germ cell development ; GO:0007281 | inferred from mutant phenotype" P granule ; GO:0043186 | non-traceable author statement pole plasm ; GO:0045495 | traceable author statement pole plasm ; GO:0045495 | inferred from direct assay P granule ; GO:0043186 | traceable author statement P granule ; GO:0043186 | inferred from direct assay "pgc-1, Pgc, pgr, Pgc1, CG11296, CR32885, pgc, CG32885" - CG32885 27-Aug-18 DroID_v2018_08 - - - - - - "viable,body color defective,lethal - all die before end of embryonic stage,some die during embryonic stage" "mesothoracic tergum,pole cell,gonad" DRSC04099 E -1.48869092 0.286435893 3.129323254 0.228627332 0.121689279 -0.579230664 FBgn0265001 ppk18 pickpocket 18 http://flybase.org/reports/FBgn0265001 protein_coding_gene sodium channel activity ; GO:0005272 | inferred from sequence or structural similarity with MGI:MGI:101782 sodium ion transport ; GO:0006814 | inferred from sequence or structural similarity with MGI:MGI:101782 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with MGI:MGI:101782 "CG13120, CG13121, ppk18, CG44152" IPR001873:Epithelial sodium channel CG44152 27-Aug-18 DroID_v2018_08 "Drer\asic2, Drer\asic4a, Drer\asic1a, Drer\asic4b, Drer\asic1b, Drer\asic1c" - "Cele\delm-2, Cele\acd-5, Cele\acd-2, Cele\acd-4, Cele\acd-1, Cele\delm-1, Cele\del-7, Cele\flr-1" "Xtro\scnn1b, Xtro\scnn1g, Xtro\asic4, Xtro\asic5, Xtro\scnn1a, Xtro\scnn1d, Xtro\asic1" "Mmus\Scnn1a, Mmus\Asic1, Mmus\Asic4, Mmus\Scnn1b, Mmus\Asic2, Mmus\Asic3, Mmus\Asic5, Mmus\Scnn1g" "Hsap\ASIC1, Hsap\SCNN1G, Hsap\SCNN1B, Hsap\ASIC3, Hsap\ASIC2, Hsap\SCNN1A, Hsap\SCNN1D, Hsap\ASIC4, Hsap\ASIC5" FBgn0058445 CG40445 - http://flybase.org/reports/FBgn0058445 protein_coding_gene - - - CG40445 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031125 CG11692 - http://flybase.org/reports/FBgn0031125 protein_coding_gene - - - CG11692 - - 27-Aug-18 DroID_v2018_08 - - - - - - DRSC20484 K 0.849424643 -0.142604461 0.044316624 0.13591258 -0.469378822 -1.725126463 FBgn0267499 5.8SrRNA:CR45839 5.8S ribosomal RNA:CR45839 http://flybase.org/reports/FBgn0267499 rRNA_gene - - - "5.8SrRNA:CR45839, CR45839" - CR45839 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031901 CG13785 - http://flybase.org/reports/FBgn0031901 protein_coding_gene - - - CG13785 - - 27-Aug-18 DroID_v2018_08 - - - - - - DRSC02288 K -0.180250639 -0.230306034 -0.41107337 0.3600402 -1.696993814 -0.554800955 FBgn0026174 SkpD SKP1-related D http://flybase.org/reports/FBgn0026174 "FBgn0031072, FBgn0047345" protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence or structural similarity with SGD:S000002736 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from sequence or structural similarity with SGD:S000002736 SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence or structural similarity with SGD:S000002736 "CG12700, dskpD, BcDNA:AT18217, Skp, SkpD, skpD" "IPR011333:SKP1/BTB/POZ domain, IPR001232:S-phase kinase-associated protein 1-like, IPR016072:SKP1 component, dimerisation, IPR016073:SKP1 component, POZ domain, IPR016897:S-phase kinase-associated protein 1" CG12700 27-Aug-18 DroID_v2018_08 Drer\skp1 Scer\SKP1 "Cele\skr-18, Cele\skr-20, Cele\skr-15, Cele\skr-5, Cele\skr-9, Cele\skr-7, Cele\skr-1, Cele\skr-10, Cele\skr-14, Cele\skr-13, Cele\skr-12, Cele\skr-21, Cele\skr-6, Cele\skr-16, Cele\skr-2, Cele\skr-3, Cele\skr-4, Cele\skr-19, Cele\skr-17, Cele\skr-8" Xtro\skp1 Mmus\Skp1a Hsap\SKP1 "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0023135 WppH White prepupal locus H http://flybase.org/reports/FBgn0023135 - gene - - - "9, 36, 22B, WppH" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0050251 tRNA:His-GTG-1-3 transfer RNA:Histidine-GTG 1-3 http://flybase.org/reports/FBgn0050251 tRNA_gene CAC codon-amino acid adaptor activity ; GO:0033426 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033426 cytosol ; GO:0005829 | inferred by curator from GO:0033426 "AE002787.trna19-HisGTG, tRNA:H:GTG:AE002787-b, CR30251, tRNA[His], chr2R.trna78-HisGTG, tRNA-His-GTG-1-3, tRNA:His-GTG-1-3, tRNA:CR30251, CAC" - CR30251 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0028644 beat-Ic beaten path Ic http://flybase.org/reports/FBgn0028644 protein_coding_gene molecular_function ; GO:0003674 | no biological data available axon guidance ; GO:0007411 | inferred from mutant phenotype defasciculation of motor neuron axon ; GO:0007415 | inferred from genetic interaction with beat-Ia heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0007157 | inferred from genetic interaction with beat-Ia integral component of plasma membrane ; GO:0005887 | inferred from sequence model "beat-C, beat Ic, CT15531, BG:DS00913.1, CG4838, beat-Ic, Beat-Ic" "IPR007110:Immunoglobulin-like domain, IPR013162:CD80-like, immunoglobulin C2-set, IPR013783:Immunoglobulin-like fold" CG4838 27-Aug-18 DroID_v2018_08 "Drer\f11r.2, Drer\jam2b" - - - - "Hsap\CADM2, Hsap\F11R" "lethal,lethal - all die before end of pupal stage,some die during pupal stage" "intersegmental nerve,transverse nerve,RP3 motor neuron,RP1 motor neuron" DRSC03491 I -0.689103294 -1.766771426 -1.232159393 -0.915894067 0.44087451 -0.574603779 FBgn0264829 CG44037 - http://flybase.org/reports/FBgn0264829 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44037 - CG44037 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0067096 H84 H84 http://flybase.org/reports/FBgn0067096 gene - - - H84 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,viable" FBgn0260436 CG42531 - http://flybase.org/reports/FBgn0260436 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42531 - CG42531 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0067810 anon-N1 anon-N1 http://flybase.org/reports/FBgn0067810 gene - - - "N1, anon-N1" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0062978 CG31808 - http://flybase.org/reports/FBgn0062978 protein_coding_gene - - - "CG31808, RE70695, BcDNA:RE70695, MRE33, CR31808" - CG31808 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000915 fs(1)ne1 female sterile (1) no eggs 1 http://flybase.org/reports/FBgn0000915 - gene - - - "ne1, fs(1)ne[1], fs(1)ne1" - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive,female sterile soma-dependent" "oocyte,endochorion,stage S10A oocyte,stage S10B oocyte,dorsal appendage,chorion" FBgn0036768 CG7402 - http://flybase.org/reports/FBgn0036768 protein_coding_gene sulfuric ester hydrolase activity ; GO:0008484 | inferred from electronic annotation with InterPro:IPR000917 "metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR000917, InterPro:IPR017849, InterPro:IPR017850" - CG7402 "IPR000917:Sulfatase, N-terminal, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha, IPR017850:Alkaline-phosphatase-like, core domain, IPR024607:Sulfatase, conserved site" CG7402 27-Aug-18 DroID_v2018_08 "Drer\arsb, Drer\arsia, Drer\ids, Drer\sgsh, Drer\galns, Drer\LOC563783, Drer\LOC101884179, Drer\arsh, Drer\LOC559800, Drer\arsa, Drer\si:dkey-174i8.1, Drer\arsg" - Cele\sul-3 "Xtro\arsb, Xtro\arsd, Xtro\arsi, Xtro\arsj, Xtro\arsa.1, Xtro\arsk, Xtro\sgsh, Xtro\arsh, Xtro\ids, Xtro\sts" "Mmus\Arsj, Mmus\Sgsh, Mmus\Arsi, Mmus\Arsa, Mmus\Arsg, Mmus\Arsb, Mmus\Ids, Mmus\Galns" "Hsap\STS, Hsap\ARSF, Hsap\GALNS, Hsap\SGSH, Hsap\ARSG, Hsap\IDS, Hsap\ARSB, Hsap\ARSJ, Hsap\ARSE, Hsap\ARSA, Hsap\ARSI, Hsap\ARSD, Hsap\ARSH" "viable,fertile" FBgn0259255 EP-469.2 - http://flybase.org/reports/FBgn0259255 gene - - - EP-469.2 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing vein,wing margin,chaeta,ectopic" FBgn0051602 tRNA:Asp-GTC-1-6 transfer RNA:Aspartic acid-GTC 1-6 http://flybase.org/reports/FBgn0051602 tRNA_gene GAC codon-amino acid adaptor activity ; GO:0033458 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033458 cytosol ; GO:0005829 | inferred by curator from GO:0033458 "Asp-tRNA, AE002690.trna6-AspGTC, tRNA:asp2:29E, tRNA:D2:29E, tRNA:D:GTC:AE002690-b, CR31602, tRNA[[Asp]], tRNA[Asp-GTC], chr2L.trna15-AspGTC, tRNA:Asp-GTC-1-6, tRNA:CR31602, tRNA-Asp-GTC-1-6, GAC" - CR31602 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005217 l(3)ET8 lethal Elaine Tasaka 8 http://flybase.org/reports/FBgn0005217 - gene - - - l(3)ET8 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,heat sensitive,male sterile" FBgn0083017 snoRNA:Psi18S-841c snoRNA:Psi18S-841c http://flybase.org/reports/FBgn0083017 snoRNA_gene - - - "snoRNA:Psi18S-841c, Psi18S-841c, psi18S-841c, CR34553, chr2R:16838224..16838314" - CR34553 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000651 febB feeding behavior B http://flybase.org/reports/FBgn0000651 - gene - - - febB - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,behavior defective,recessive,feeding behavior defective,somatic clone" FBgn0031826 CG9550 - http://flybase.org/reports/FBgn0031826 protein_coding_gene N-acetylglucosamine 6-O-sulfotransferase activity ; GO:0001517 | inferred from biological aspect of ancestor with PANTHER:PTN000842280 sulfur compound metabolic process ; GO:0006790 | inferred from biological aspect of ancestor with PANTHER:PTN001322541 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN001322541 "CG9550, d6ST2" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR000863:Sulfotransferase domain" CG9550 27-Aug-18 DroID_v2018_08 "Drer\zgc:194879, Drer\chst2b, Drer\chst3b, Drer\chst2a, Drer\chst1, Drer\chst7, Drer\chst3a, Drer\si:ch73-62b13.1" - - "Xtro\chst1, Xtro\chst4, Xtro\chst2, Xtro\chst7, Xtro\chst6, Xtro\chst3" "Mmus\Chst5, Mmus\Chst7, Mmus\Chst1, Mmus\Chst4, Mmus\Chst3, Mmus\Chst2" "Hsap\CHST7, Hsap\CHST4, Hsap\CHST1, Hsap\CHST3, Hsap\CHST5, Hsap\CHST6, Hsap\CHST2" viable FBgn0030777 CG9672 - http://flybase.org/reports/FBgn0030777 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314" extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000669108 "SPH161, BcDNA:GH16384, CG9672" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan" CG9672 27-Aug-18 DroID_v2018_08 "Drer\proca, Drer\si:ch211-165b19.9, Drer\si:dkey-21e2.3, Drer\gzm3, Drer\proza, Drer\gzma, Drer\LOC558805, Drer\si:dkey-21e2.16, Drer\zgc:171509, Drer\zgc:163025, Drer\si:ch211-165b19.8, Drer\prozb, Drer\gzmk" - - - "Mmus\Klk12, Mmus\Proc, Mmus\Proz" "Hsap\PROC, Hsap\PROZ" viable FBgn0011167 l(1)DM-4 lethal (1) DM-4 http://flybase.org/reports/FBgn0011167 FBgn0010204 gene - - - l(1)DM-4 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0003243 rfr refringent http://flybase.org/reports/FBgn0003243 - gene - oogenesis ; GO:0048477 | traceable author statement - "ref, rfr" - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive,visible,viable,male,male fertile,female,reduced" wing FBgn0034942 CG13566 - http://flybase.org/reports/FBgn0034942 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13566 - CG13566 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC04203 I -1.617712005 -1.058909333 -0.100310023 0.839259811 0.769476694 0.777256016 FBgn0026873 MED18 Mediator complex subunit 18 http://flybase.org/reports/FBgn0026873 - protein_coding_gene RNA polymerase II transcription cofactor activity ; GO:0001104 | contributes_to inferred by curator from GO:0016592 RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from mutant phenotype protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8MSX2 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from electronic annotation with InterPro:IPR019095 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred by curator from GO:0016592 transcription from RNA polymerase II promoter ; GO:0006366 | inferred from mutant phenotype termination of RNA polymerase II transcription ; GO:0006369 | inferred from biological aspect of ancestor with PANTHER:PTN001410513 core mediator complex ; GO:0070847 | inferred from biological aspect of ancestor with PANTHER:PTN001410513 nucleus ; GO:0005634 | inferred from direct assay mediator complex ; GO:0016592 | inferred from direct assay "CG14802, Med18, p28/CG14802, Srb5/Med28b, dp28b, EG:63B12.13, p28, MED18" "IPR019095:Mediator complex, subunit Med18, metazoa/fungi" CG14802 27-Aug-18 DroID_v2018_08 Drer\med18 Scer\SRB5 Cele\mdt-18 Xtro\med18 Mmus\Med18 Hsap\MED18 "cell growth defective,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,chaeta,supernumerary" FBgn0020566 anon-88Ad anon-88Ad http://flybase.org/reports/FBgn0020566 - gene - - - anon-88Ad - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001521 l(1)11Ae lethal (1) 11Ae http://flybase.org/reports/FBgn0001521 - gene - - - "l(1)L2, 2, l(1)11Ae" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0259990 CG42487 - http://flybase.org/reports/FBgn0259990 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42487 - CG42487 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030871 CG8142 - http://flybase.org/reports/FBgn0030871 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959 DNA clamp loader activity ; GO:0003689 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000186208 cytoplasmic microtubule organization ; GO:0031122 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype DNA-dependent DNA replication ; GO:0006261 | inferred from biological aspect of ancestor with PANTHER:PTN000186208 Elg1 RFC-like complex ; GO:0031391 | inferred from direct assay DNA replication factor C complex ; GO:0005663 | inferred from biological aspect of ancestor with PANTHER:PTN000186208 microtubule associated complex ; GO:0005875 | inferred from direct assay "CG8142, RfC, DmRFC2, RFC2, Rfc37" "IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR008921:DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal, IPR013748:Replication factor C, C-terminal, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG8142 27-Aug-18 DroID_v2018_08 "Drer\rfc4, Drer\rfc2, Drer\rfc5" Scer\RFC2 "Cele\rfc-2, Cele\F44B9.8, Cele\rfc-4" "Xtro\rfc2, Xtro\rfc5, Xtro\rfc4" "Mmus\Rfc2, Mmus\Rfc5, Mmus\Rfc4" "Hsap\RFC2, Hsap\RFC4, Hsap\RFC5" "viable,fertile,visible" "chaeta,trichogen cell" FBgn0003977 vir virilizer http://flybase.org/reports/FBgn0003977 FBgn0034852 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from sequence or structural similarity with protein_id:AAC03114.1 inferred from sequence or structural similarity with protein_id:CAA53660.1 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9Y091 "regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype primary sex determination, soma ; GO:0007539 | non-traceable author statement sex determination ; GO:0007530 | traceable author statement RNA splicing, via transesterification reactions ; GO:0000375 | inferred from mutant phenotype regulation of mRNA splicing, via spliceosome ; GO:0048024 | traceable author statement dosage compensation ; GO:0007549 | traceable author statement" integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity nucleus ; GO:0005634 | inferred from sequence or structural similarity inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG3496, vir, Vir" "IPR026736:Protein virilizer, IPR031801:Virilizer, N-terminal" CG3496 27-Aug-18 DroID_v2018_08 Drer\si:ch211-79l20.4 - - Xtro\kiaa1429 Mmus\1110037F02Rik Hsap\KIAA1429 "lethal,recessive,wild-type,sex-determination defective,female,heat sensitive,viable,lethal - all die before end of larval stage,some die during larval stage,female sterile,maternal effect,male,male fertile,partially lethal - majority die,visible" "border follicle cell,somatic clone,adult abdomen,heat sensitive,abdominal tergite 6,abdominal tergite 7,oviprotector,female gonopod,anal plate,hypoproct,chaeta,supernumerary,trichogen cell,mesothoracic tergum" FBgn0262636 dati datilografo http://flybase.org/reports/FBgn0262636 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 neuron projection development ; GO:0031175 | inferred from mutant phenotype generation of neurons ; GO:0048699 | inferred from mutant phenotype adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype positive regulation of female receptivity ; GO:0045925 | inferred from mutant phenotype - "CG2052, dati, CG10204, DmLin29, Lin29" IPR013087:Zinc finger C2H2-type CG2052 27-Aug-18 DroID_v2018_08 "Drer\si:dkeyp-121d2.7, Drer\si: zfos-932h1.3, Drer\LOC100534979, Drer\znf1174, Drer\znf362b, Drer\znf362a" Scer\AZF1 Cele\lin-29 "Xtro\zxdc, Xtro\znf362" "Mmus\Zxdc, Mmus\Zxdb, Mmus\Zfp236, Mmus\Zfp217, Mmus\Zfp362" "Hsap\ZBTB48, Hsap\ZXDB, Hsap\ZNF362, Hsap\ZXDA, Hsap\ZXDC" FBgn0264489 CG43897 - http://flybase.org/reports/FBgn0264489 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR005822 translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR005822 lateral inhibition ; GO:0046331 | inferred from mutant phenotype mesoderm development ; GO:0007498 | inferred from expression pattern ribosome ; GO:0005840 | inferred from electronic annotation with InterPro:IPR005822 "CG43897, CG33205, CG32050, CG8154, CG8163, CG14172, CG32051, CG32049, BcDNA:RH19933, BcDNA:RE55923" "IPR005822:Ribosomal protein L13, IPR006643:Zasp-like motif, IPR031847:Domain of unknown function DUF4749" CG43897 27-Aug-18 DroID_v2018_08 "Drer\pdlim1, Drer\pdlim3b, Drer\pdlim2, Drer\pdlim4, Drer\pdlim3a" - - - "Mmus\Pdlim2, Mmus\Pdlim3, Mmus\Pdlim4, Mmus\Prickle4, Mmus\Pdlim1" "Hsap\BRD4, Hsap\PDLIM1, Hsap\PRICKLE4, Hsap\PDLIM3, Hsap\PDLIM2, Hsap\PDLIM4" FBgn0265778 PDZ-GEF PDZ domain-containing guanine nucleotide exchange factor http://flybase.org/reports/FBgn0265778 protein_coding_gene Rap guanyl-nucleotide exchange factor activity ; GO:0017034 | inferred from sequence or structural similarity with HGNC:16854 Ras GTPase binding ; GO:0017016 | inferred from physical interaction with Rap1 Rap guanyl-nucleotide exchange factor activity ; GO:0017034 | inferred from direct assay "small GTPase mediated signal transduction ; GO:0007264 | inferred from electronic annotation with InterPro:IPR001895, InterPro:IPR019804 oogenesis ; GO:0048477 | inferred from mutant phenotype germ-line stem cell population maintenance ; GO:0030718 | inferred from mutant phenotype MAPK cascade ; GO:0000165 | inferred from genetic interaction with Raf inferred from genetic interaction with rl inferred from genetic interaction with Dsor1 adherens junction assembly ; GO:0034333 | inferred from genetic interaction with Rap1 hemocyte migration ; GO:0035099 | inferred from mutant phenotype substrate-dependent cell migration, cell extension ; GO:0006930 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype imaginal disc-derived male genitalia development ; GO:0007485 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype regulation of embryonic cell shape ; GO:0016476 | inferred from mutant phenotype positive regulation of GTPase activity ; GO:0043547 | inferred from sequence or structural similarity with HGNC:16854 regulation of compound eye photoreceptor development ; GO:0045314 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype inferred from genetic interaction with Rap1, cno, zip" apicolateral plasma membrane ; GO:0016327 | inferred from direct assay adherens junction ; GO:0005912 | colocalizes_with inferred from direct assay "EC2-8, Gef26, PDZ-GEF, dizzy, CG9491, dzy, dPDZ-GEF, PDF-GEF Dizzy, l(2)k13720, GEF, D-PDZGEF, DGEF, Dzy" "IPR029071:Ubiquitin-related domain, IPR023578:Ras guanine nucleotide exchange factor domain, IPR019804:Ras guanine-nucleotide exchange factor, conserved site, IPR014710:RmlC-like jelly roll fold, IPR001895:Ras guanine-nucleotide exchange factors catalytic domain, IPR001478:PDZ domain, IPR000651:Ras-like guanine nucleotide exchange factor, N-terminal, IPR000595:Cyclic nucleotide-binding domain, IPR000159:Ras-associating (RA) domain, IPR018490:Cyclic nucleotide-binding-like" CG9491 27-Aug-18 DroID_v2018_08 "Drer\rasgrf2b, Drer\si:ch211-234p18.3, Drer\rapgef1a, Drer\sos1, Drer\si:dkey-253i9.4, Drer\rapgef1b, Drer\rapgef6, Drer\rapgef2" "Scer\LTE1, Scer\CDC25" "Cele\Y34B4A.4, Cele\pxf-1, Cele\sos-1" - "Mmus\Rasgrf1, Mmus\Rapgef1, Mmus\Rapgef6, Mmus\Rasgrf2, Mmus\Rapgef2, Mmus\Sos1, Mmus\Sos2" "Hsap\RAPGEF6, Hsap\RASGRF1, Hsap\RASGRF2, Hsap\SOS2, Hsap\RAPGEF2, Hsap\SOS1, Hsap\RAPGEF1" DRSC03231 E -1.115914075 -0.531928597 -1.770098189 -0.470963788 1.111480823 -0.889726447 FBgn0052576 CG32576 - http://flybase.org/reports/FBgn0052576 protein_coding_gene molecular_function ; GO:0003674 | no biological data available vesicle-mediated transport ; GO:0016192 | inferred from electronic annotation with InterPro:IPR007305 cellular_component ; GO:0005575 | no biological data available "NEST:bs01h05, anon-AE003501.1, BcDNA:RE29988, CG32576" "IPR007305:Vesicle transport protein, Got1/SFT2-like" CG32576 27-Aug-18 DroID_v2018_08 "Drer\golt1bb, Drer\golt1a, Drer\golt1ba" Scer\GOT1 Cele\F41C3.4 Xtro\golt1b "Mmus\Golt1b, Mmus\Golt1a" "Hsap\GOLT1B, Hsap\GOLT1A" DRSC19136 K 0.084884855 0.342205001 0.130742592 -0.608990982 0.120520048 1.589680424 FBgn0033104 CG15237 - http://flybase.org/reports/FBgn0033104 protein_coding_gene - regulation of mitotic cell cycle spindle assembly checkpoint ; GO:0090266 | inferred from electronic annotation with InterPro:IPR026182 anaphase-promoting complex ; GO:0005680 | inferred from electronic annotation with InterPro:IPR026182 "CG15237, APC15" IPR026182:Anaphase-promoting complex subunit 15 CG15237 27-Aug-18 DroID_v2018_08 Drer\anapc15 - - - Mmus\Anapc15 Hsap\ANAPC15 viable FBgn0040630 CG12710 - http://flybase.org/reports/FBgn0040630 protein_coding_gene - - - CG12710 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0052029 Cpr66D Cuticular protein 66D http://flybase.org/reports/FBgn0052029 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "CG6458, CG6469, Cpr66D, CG32029, DmelCpr66D" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG32029 27-Aug-18 DroID_v2018_08 - - Cele\fbxb-38 - - - "viable,fertile" FBgn0040336 Seipin Seipin http://flybase.org/reports/FBgn0040336 protein_coding_gene molecular_function ; GO:0003674 | no biological data available response to starvation ; GO:0042594 | inferred from mutant phenotype fatty acid beta-oxidation ; GO:0006635 | inferred from mutant phenotype regulation of lipid biosynthetic process ; GO:0046890 | inferred from mutant phenotype inferred from genetic interaction with mdy inferred from genetic interaction with mino inferred from genetic interaction with SCAP regulation of triglyceride metabolic process ; GO:0090207 | inferred from mutant phenotype lipid biosynthetic process ; GO:0008610 | inferred from mutant phenotype positive regulation of lipid storage ; GO:0010884 | inferred from mutant phenotype endoplasmic reticulum calcium ion homeostasis ; GO:0032469 | inferred from mutant phenotype regulation of lipid storage ; GO:0010883 | inferred from mutant phenotype phosphatidic acid metabolic process ; GO:0046473 | inferred from mutant phenotype diacylglycerol metabolic process ; GO:0046339 | inferred from mutant phenotype endoplasmic reticulum ; GO:0005783 | inferred from direct assay "EG:BACR7C10.1, CG9904, Seipin, dSeipin" IPR009617:Seipin family CG9904 27-Aug-18 DroID_v2018_08 "Drer\bscl2l, Drer\bscl2" - Cele\R01B10.6 Xtro\bscl2 Mmus\Bscl2 Hsap\BSCL2 "decreased cell size,somatic clone,viable,fertile,lethal,nutrition conditional" "adult fat body,somatic clone,lipid particle | somatic clone,embryonic/larval fat body,nutrition conditional,fat body,salivary gland,lipid particle | ectopic,lipid particle,lipid particle | ectopicppl.PP,lipid particleppl.PP,lipid particle | ectopicelav.PU,lipid particle | ectopic48Y" FBgn0019731 l(1)A17 lethal (1) A17 http://flybase.org/reports/FBgn0019731 - gene - - - l(1)A17 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0028086 l(3)S084805 lethal (3) S084805 http://flybase.org/reports/FBgn0028086 gene - - - "0848/05, l(3)S084805" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0283680 IP3K2 "Inositol 1,4,5-triphosphate kinase 2" http://flybase.org/reports/FBgn0283680 protein_coding_gene "calcium-dependent protein binding ; GO:0048306 | inferred from direct assay calmodulin binding ; GO:0005516 | inferred from direct assay inositol-1,4,5-trisphosphate 3-kinase activity ; GO:0008440 | inferred from direct assay" salivary gland cell autophagic cell death ; GO:0035071 | inferred from mutant phenotype inferred from genetic interaction with mir-14 inositol phosphate biosynthetic process ; GO:0032958 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "wy, IP3K2, CG15745, ip3k2, CG45017, dmIP[[3]]beta, CG1630, IP[[3]]K2, CG34359, dmIP3Kbeta, dmIP3K2, DIP3K2, D-IP3K2, CG12724, NP2758, IP[[3]]K-2, CG4501" "IPR005522:Inositol polyphosphate kinase, IPR011989:Armadillo-like helical" CG45017 27-Aug-18 DroID_v2018_08 "Drer\itpka, Drer\itpkcb, Drer\itpkb, Drer\itpkca, Drer\si:ch73-22a13.3" - Cele\lfe-2 "Xtro\itpkb, Xtro\itpka, Xtro\itpkc" "Mmus\Itpkb, Mmus\Itpka, Mmus\Itpkc" "Hsap\ITPKB, Hsap\ITPKA, Hsap\ITPKC" "visible,viable,fertile,lethal,male" "wing,abdomen,wing vein L1" FBgn0066330 rafl rafael http://flybase.org/reports/FBgn0066330 gene molecular_function ; GO:0003674 | no biological data available learning or memory ; GO:0007611 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype visual learning ; GO:0008542 | inferred from mutant phenotype visual behavior ; GO:0007632 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available rafl - - 27-Aug-18 DroID_v2018_08 - - - - - - "memory defective,visual behavior defective,recessive,learning defective,neurophysiology defective,chemical sensitive" FBgn0050042 Cpr49Ab Cuticular protein 49Ab http://flybase.org/reports/FBgn0050042 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "CG8496, Cpr49Ab, CG30042, DmelCpr49Ab" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG30042 27-Aug-18 DroID_v2018_08 Drer\LOC100003040 - "Cele\F44F1.4, Cele\sdz-30, Cele\math-34" - "Mmus\2410137M14Rik, Mmus\H2-K1" - viable FBgn0040132 l(2)22Ag lethal (2) 22Ag http://flybase.org/reports/FBgn0040132 gene - - - "A, l(2)22Ag" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0037382 Hpr1 Hpr1 http://flybase.org/reports/FBgn0037382 protein_coding_gene - signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR000488 mRNA export from nucleus in response to heat stress ; GO:0031990 | inferred from mutant phenotype "protein complex ; GO:0043234 | inferred from physical interaction with thoc5, thoc7 THO complex ; GO:0000347 | inferred from direct assay transcription export complex ; GO:0000346 | inferred from sequence or structural similarity with HGNC:19070 nucleus ; GO:0005634 | inferred from direct assay" "CG2031, Hpr1, HPR1, Thoc1" "IPR000488:Death domain, IPR011029:Death-like domain, IPR021861:THO complex, subunit THOC1" CG2031 27-Aug-18 DroID_v2018_08 "Drer\thoc1, Drer\si:dkeyp-97b10.3, Drer\LOC103911624" - Cele\thoc-1 Xtro\thoc1 Mmus\Thoc1 Hsap\THOC1 viable DRSC12296 I 1.628419054 0.724526984 -0.937161093 -0.094311899 0.863421026 0.11575848 FBgn0267291 lncRNA:CR45727 - http://flybase.org/reports/FBgn0267291 non_protein_coding_gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype - CR45727 - CR45727 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0015727 Est-F Est-F http://flybase.org/reports/FBgn0015727 - gene - - - "Est-Fs, Est-F" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0046668 anon-38C.29 anon-38C.29 http://flybase.org/reports/FBgn0046668 gene - - - "38C.29, anon-38C.29" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0014314 l(3)ry114 lethal (3) ry114 http://flybase.org/reports/FBgn0014314 - gene - - - l(3)ry114 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0065325 l(2)SH1898 lethal (2) SH1898 http://flybase.org/reports/FBgn0065325 gene - - - "l(2)SH1898, l(2)SH2 1898" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0031626 CG15631 - http://flybase.org/reports/FBgn0031626 protein_coding_gene - - - CG15631 - CG15631 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0261553 CG42671 - http://flybase.org/reports/FBgn0261553 protein_coding_gene - - - "CG42671, CG18490, CG34240" - CG42671 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065507 l(2)SH1185 lethal (2) SH1185 http://flybase.org/reports/FBgn0065507 gene - - - l(2)SH1185 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0040993 CG17325 - http://flybase.org/reports/FBgn0040993 protein_coding_gene - - - "BcDNA:RH02271, CG17325, Dromel_CG17325_FBtr0081102_mORF" - CG17325 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263314 CG43400 - http://flybase.org/reports/FBgn0263314 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43400, lincRNA.75" - CG43400 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030395 Mks1 "Meckel syndrome, type 1" http://flybase.org/reports/FBgn0030395 protein_coding_gene - ciliary transition zone assembly ; GO:1905349 | inferred from mutant phenotype axoneme assembly ; GO:0035082 | inferred from mutant phenotype non-motile cilium assembly ; GO:1905515 | inferred from mutant phenotype regulation of establishment of planar polarity ; GO:0090175 | inferred from mutant phenotype ciliary transition zone ; GO:0035869 | inferred from direct assay MKS complex ; GO:0036038 | inferred from sequence or structural similarity with MGI:MGI:3584243 "CG15730, Mks1, dMks1" IPR010796:B9 domain CG15730 27-Aug-18 DroID_v2018_08 Drer\mks1 - Cele\mks-1 Xtro\mks1 Mmus\Mks1 Hsap\MKS1 "viable,planar polarity defective,visible" "ommatidium,wing hair,supernumerary,wing blade" FBgn0053094 Synd Syndapin http://flybase.org/reports/FBgn0053094 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with scra phospholipid binding ; GO:0005543 | inferred from sequence model lipid binding ; GO:0008289 | inferred from direct assay synaptic vesicle endocytosis ; GO:0048488 | non-traceable author statement membrane organization ; GO:0061024 | inferred from direct assay positive regulation of synaptic growth at neuromuscular junction ; GO:0045887 | inferred from mutant phenotype cleavage furrow ingression ; GO:0036090 | inferred from mutant phenotype male meiosis cytokinesis ; GO:0007112 | inferred from mutant phenotype spindle assembly involved in male meiosis ; GO:0007053 | inferred from mutant phenotype neurotransmitter secretion ; GO:0007269 | non-traceable author statement mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype regulation of endocytosis ; GO:0030100 | inferred from biological aspect of ancestor with PANTHER:PTN000860688 postsynaptic membrane ; GO:0045211 | inferred from direct assay subsynaptic reticulum ; GO:0071212 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay endosome ; GO:0005768 | inferred from biological aspect of ancestor with PANTHER:PTN000860688 cleavage furrow ; GO:0032154 | inferred from direct assay midbody ; GO:0030496 | inferred from direct assay "CG15694, D-Synd, CG33094, Synd, synd" "IPR001060:FCH domain, IPR001452:SH3 domain, IPR027267:Arfaptin homology (AH) domain/BAR domain, IPR031160:F-BAR domain" CG33094 27-Aug-18 DroID_v2018_08 "Drer\pacsin1a, Drer\si:ch211-51c14.1, Drer\zgc:91999, Drer\arfgap2, Drer\trip10a, Drer\itsn1, Drer\itsn2b, Drer\arfgap3, Drer\pacsin3, Drer\sh3d19, Drer\pacsin2, Drer\itsn2a, Drer\pacsin1b" "Scer\BZZ1, Scer\LSB3, Scer\HOF1, Scer\LSB1, Scer\YSC84, Scer\SYP1" "Cele\B0303.7, Cele\itsn-1, Cele\F07F6.4, Cele\sdpn-1, Cele\toca-1" "Xtro\pacsin2, Xtro\MGC147475, Xtro\pacsin1, Xtro\pacsin3, Xtro\fnbp1l, Xtro\arfgap2" "Mmus\Sh3d19, Mmus\Pacsin2, Mmus\Arfgap2, Mmus\Sh3yl1, Mmus\Itsn1, Mmus\Pacsin1, Mmus\Fnbp1, Mmus\Pacsin3, Mmus\Arfgap3, Mmus\Trip10, Mmus\Fnbp1l, Mmus\Itsn2" "Hsap\SH3D19, Hsap\ARFGAP3, Hsap\ITSN2, Hsap\SH3YL1, Hsap\PACSIN1, Hsap\ARFGAP2, Hsap\PACSIN2, Hsap\ITSN1, Hsap\PACSIN3, Hsap\FNBP1L, Hsap\FNBP1, Hsap\FCHSD1, Hsap\GRAP2, Hsap\TRIP10" "lethal - all die before end of pupal stage,some die during pupal stage,viable,majority die during third instar larval stage,cytokinesis defective,meiotic cell cycle defective,body color defective" "subsynaptic reticulum | third instar larval stageMef2.PR,postsynaptic membrane | third instar larval stageMef2.PR,subsynaptic reticulum | third instar larval stagetub.PU,onion stage spermatid,spermatocyte,spindle midzoneBSC43),contractile ringBSC43),cleavage furrowBSC43),meiotic spindleBSC43),mesothoracic tergum" FBgn0259403 C747 - http://flybase.org/reports/FBgn0259403 gene - - - C747 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible wing vein FBgn0060582 l(3)S094615b lethal (3) S094615b http://flybase.org/reports/FBgn0060582 gene - - - "0946/15, l(3)S094615b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0083236 EP364 EP364 http://flybase.org/reports/FBgn0083236 gene - - - EP364 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039387 MCO3 multicopper oxidase 3 http://flybase.org/reports/FBgn0039387 protein_coding_gene "copper ion binding ; GO:0005507 | inferred from electronic annotation with InterPro:IPR002355, InterPro:IPR011706, InterPro:IPR011707 iron ion transmembrane transporter activity ; GO:0005381 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001709969 ferroxidase activity ; GO:0004322 | inferred from biological aspect of ancestor with PANTHER:PTN001709969" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001117, InterPro:IPR011706 iron ion transport ; GO:0006826 | inferred from biological aspect of ancestor with PANTHER:PTN001709969 iron assimilation by reduction and transport ; GO:0033215 | inferred from biological aspect of ancestor with PANTHER:PTN001709969 copper ion homeostasis ; GO:0055070 | inferred from direct assay" high-affinity iron permease complex ; GO:0033573 | inferred from biological aspect of ancestor with PANTHER:PTN001709969 "MCO3, CG5959, MIP26036" "IPR001117:Multicopper oxidase, type 1, IPR002355:Multicopper oxidase, copper-binding site, IPR008972:Cupredoxin, IPR011706:Multicopper oxidase, type 2, IPR011707:Multicopper oxidase, type 3, IPR033138:Multicopper oxidases, conserved site" CG5959 27-Aug-18 DroID_v2018_08 "Drer\cp, Drer\hephl1b" "Scer\GMC1, Scer\FET3, Scer\FET5" Cele\F21D5.3 Xtro\hephl1 "Mmus\Heph, Mmus\Hephl1, Mmus\Cp" "Hsap\CP, Hsap\HEPHL1, Hsap\HEPH" "viable,fertile" FBgn0262103 Sik3 Salt-inducible kinase 3 http://flybase.org/reports/FBgn0262103 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with HGNC:21680 protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000678822 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement" protein phosphorylation ; GO:0006468 | inferred from biological aspect of ancestor with PANTHER:PTN000678822 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype cellular response to hormone stimulus ; GO:0032870 | inferred from biological aspect of ancestor with PANTHER:PTN001552066 protein phosphorylation ; GO:0006468 | non-traceable author statement lipid homeostasis ; GO:0055088 | inferred from mutant phenotype intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN000678822 protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with HGNC:21680 response to starvation ; GO:0042594 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000678822 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000678822 "CG15072, SIK, SIK3, Sik3, CG42856, EMK/KIAA0999, CG18604" "IPR028375:KA1 domain/Ssp2, C-terminal, IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR001772:Kinase associated domain 1 (KA1)" CG42856 27-Aug-18 DroID_v2018_08 "Drer\sik2b, Drer\mark4a, Drer\mark3a, Drer\zgc:66101, Drer\mark3b, Drer\prkaa1, Drer\mark1, Drer\mark2a, Drer\mark2b, Drer\si:dkey-31m14.7, Drer\sik1, Drer\sik2a" "Scer\KIN2, Scer\SNF1, Scer\KIN1, Scer\PRR1" "Cele\par-1, Cele\kin-29" "Xtro\sik3, Xtro\prkaa1, Xtro\mark4, Xtro\mark2, Xtro\mark3, Xtro\sik2, Xtro\prkaa2" "Mmus\Gm6729, Mmus\Prkaa1, Mmus\Smok3b, Mmus\Gm6882, Mmus\Gm7168, Mmus\Smok2a, Mmus\1810024B03Rik, Mmus\Gm14147, Mmus\Sik1, Mmus\Mark4, Mmus\Gm4922, Mmus\Sik2, Mmus\Gm6902, Mmus\Prkaa2, Mmus\4921509C19Rik, Mmus\Gm6176, Mmus\Gm10668, Mmus\Mark3, Mmus\Mark2, Mmus\Gm14151, Mmus\Smok2b, Mmus\Gm5174, Mmus\Mark1, Mmus\Smok3a, Mmus\Sik3" "Hsap\SIK2, Hsap\SIK1, Hsap\MARK1, Hsap\SIK3, Hsap\MARK4, Hsap\PRKAA1, Hsap\MARK3, Hsap\PRKAA2, Hsap\MARK2" FBgn0021774 ms(2)985 ms(2)985 http://flybase.org/reports/FBgn0021774 - gene - - - "ms-985, ms(2)985" - - 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,recessive,viable" FBgn0083285 E(smoDN)2135 Enhancer of smoDN 2135 http://flybase.org/reports/FBgn0083285 gene - - - E(smoDN)2135 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0250897 zaa43d06 - http://flybase.org/reports/FBgn0250897 gene - - - "zaa43d06, zaa43d06x1" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0015563 vivi-repeat vivi-repeat http://flybase.org/reports/FBgn0015563 FBgn0025236 repeat_region - - - "Vivi, HP1-VS, VS, anon-EST:fe2A2, vivi-repeat" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034210 CG6568 - http://flybase.org/reports/FBgn0034210 protein_coding_gene - - - CG6568 - CG6568 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-56d12.4, Drer\zgc:113019, Drer\si:dkey-60a16.1" - - - - - viable FBgn0267180 asRNA:CR45620 - http://flybase.org/reports/FBgn0267180 non_protein_coding_gene - - - CR45620 - CR45620 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0020829 l(2)SA "South Amherst, Mass" http://flybase.org/reports/FBgn0020829 - gene - - - l(2)SA - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0065596 l(2)SH0889 lethal (2) SH0889 http://flybase.org/reports/FBgn0065596 gene - - - "l(2)SH0889, l(2)SH2 0889" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0004763 l(3)89Cd lethal (3) 89Cd http://flybase.org/reports/FBgn0004763 - gene - - - l(3)89Cd - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0043491 flea\polyprotein flea element polyprotein http://flybase.org/reports/FBgn0043491 transposable_element_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001878 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001878, InterPro:IPR012337 aspartic-type endopeptidase activity ; GO:0004190 | inferred from electronic annotation with InterPro:IPR001969, InterPro:IPR001995" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001969, InterPro:IPR001995 DNA integration ; GO:0015074 | inferred from electronic annotation with InterPro:IPR001584" - "blastopia\polyprotein, flea\polyprotein" "IPR034145:RTVL-H retropepsin domain, IPR026523:Paraneoplastic antigen Ma, IPR021109:Aspartic peptidase domain, IPR000477:Reverse transcriptase domain, IPR001584:Integrase, catalytic core, IPR001969:Aspartic peptidase, active site, IPR001995:Peptidase A2A, retrovirus, catalytic, IPR018061:Retropepsins, IPR012337:Ribonuclease H-like domain, IPR001878:Zinc finger, CCHC-type" - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031678 CG31918 - http://flybase.org/reports/FBgn0031678 protein_coding_gene metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR000718 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR008753" - "CG18592, anon-WO0118547.477, CG31918" "IPR000718:Peptidase M13, IPR008753:Peptidase M13, N-terminal domain" CG31918 27-Aug-18 DroID_v2018_08 "Drer\ece2b, Drer\mmel1, Drer\phex, Drer\ece1" - "Cele\nep-26, Cele\nep-18, Cele\nep-7, Cele\nep-5, Cele\nep-19, Cele\nep-16, Cele\nep-10, Cele\nep-13, Cele\nep-24, Cele\nep-9, Cele\nep-21, Cele\nep-3, Cele\nep-20, Cele\nep-17, Cele\nep-23, Cele\nep-12, Cele\nep-8, Cele\nep-6" "Xtro\ece2, Xtro\ece1, Xtro\ecel1, Xtro\mmel1" "Mmus\Mmel1, Mmus\Ece2, Mmus\Ece1, Mmus\Ecel1, Mmus\Mme, Mmus\Phex, Mmus\Kel" "Hsap\MME, Hsap\KEL, Hsap\PHEX, Hsap\ECE2, Hsap\MMEL1, Hsap\ECEL1, Hsap\ECE1" viable dorsal appendage FBgn0045800 Uhg1 U snoRNA host gene 1 http://flybase.org/reports/FBgn0045800 non_protein_coding_gene - - - "Dros-UHG1, dUHG1, CG14486, CR32886, BEST:GM03135, Uhg1, dUhg1, FBgn0040741" - CR32886 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264723 lncRNA:CR43991 - http://flybase.org/reports/FBgn0264723 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CR43991, CG43991" - CR43991 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005071 fs(2)OW212 female sterile (2) OW212 http://flybase.org/reports/FBgn0005071 - gene - - - fs(2)OW212 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0013259 E(var)45 E(var)45 http://flybase.org/reports/FBgn0013259 - gene - - - E(var)45 - - 27-Aug-18 DroID_v2018_08 - - - - - - "enhancer of variegation,dominant" FBgn0036325 CG10752 - http://flybase.org/reports/FBgn0036325 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon-WO0140519.236, CG10752" "IPR011705:BTB/Kelch-associated, IPR011333:SKP1/BTB/POZ domain" CG10752 27-Aug-18 DroID_v2018_08 Drer\klhl41a - - - - - viable FBgn0013550 l(3)100Ab lethal (3) 100Ab http://flybase.org/reports/FBgn0013550 - gene - - - l(3)100Ab - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0034458 Ir56d Ionotropic receptor 56d http://flybase.org/reports/FBgn0034458 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "Ir56d, DmelIR56d, CG15904, IR56d" - CG15904 27-Aug-18 DroID_v2018_08 - - Cele\W02A2.5 - - "Hsap\GRIK3, Hsap\GRIK2" viable FBgn0261630 CG42713 - http://flybase.org/reports/FBgn0261630 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 - - "CG42713, DMG4-MB6.chr2L.16.012" IPR002223:Pancreatic trypsin inhibitor Kunitz domain CG42713 27-Aug-18 DroID_v2018_08 "Drer\pi15a, Drer\r3hdml, Drer\pi15b, Drer\glipr2, Drer\crispld2, Drer\crispld1b, Drer\wu:fb59d01, Drer\LOC100536500, Drer\glipr1b, Drer\glipr2l, Drer\crispld1a" "Scer\PRY2, Scer\PRY1, Scer\PRY3" - "Xtro\crispld2, Xtro\r3hdml, Xtro\crisp2, Xtro\glipr2, Xtro\crisp3, Xtro\crisp1, Xtro\MGC108118" "Mmus\Crisp3, Mmus\Glipr2, Mmus\Glipr1, Mmus\Crispld2, Mmus\Glipr1l2, Mmus\Crisp4, Mmus\Pi15, Mmus\Crisp1, Mmus\Clec18a, Mmus\Glipr1l1, Mmus\Crisp2, Mmus\R3hdml, Mmus\Pi16, Mmus\Crispld1" "Hsap\CLEC18A, Hsap\CLEC18B, Hsap\PI16, Hsap\R3HDML, Hsap\CLEC18C, Hsap\CRISP2, Hsap\GLIPR2, Hsap\GLIPR1L2, Hsap\CRISPLD2, Hsap\GLIPR1, Hsap\CRISP1, Hsap\GLIPR1L1, Hsap\PI15, Hsap\CRISPLD1" FBgn0003119 po pale ocelli http://flybase.org/reports/FBgn0003119 - gene - ommochrome biosynthetic process ; GO:0006727 | inferred from mutant phenotype - "do, po" - - 27-Aug-18 DroID_v2018_08 - - - - - - ocellus pigment granule FBgn0038535 alt aluminum tubes http://flybase.org/reports/FBgn0038535 protein_coding_gene receptor activity ; GO:0004872 | inferred from biological aspect of ancestor with PANTHER:PTN001450043 "cuticle development ; GO:0042335 | inferred from genetic interaction with UniProtKB:Q0KHR3,UniProtKB:Q9VX75,UniProtKB:X2JCB3,UniProtKB:X2JFU8 translation ; GO:0006412 | inferred from biological aspect of ancestor with PANTHER:PTN001450043" lipid particle ; GO:0005811 | inferred from direct assay ribosome ; GO:0005840 | inferred from biological aspect of ancestor with PANTHER:PTN001450043 endomembrane system ; GO:0012505 | inferred from direct assay integral component of endoplasmic reticulum membrane ; GO:0030176 | inferred from biological aspect of ancestor with PANTHER:PTN001450043 "CG18212, alt, Q9VEH0_DROME" - CG18212 27-Aug-18 DroID_v2018_08 "Drer\rrbp1b, Drer\rrbp1a" - - Xtro\rrbp1 "Mmus\Ktn1, Mmus\Rrbp1" Hsap\RRBP1 "viable,fertile" FBgn0261850 Xpd Xeroderma pigmentosum D http://flybase.org/reports/FBgn0261850 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001945, InterPro:IPR002464, InterPro:IPR006555, InterPro:IPR010614, InterPro:IPR014013 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001945, InterPro:IPR010614 transcription factor activity, core RNA polymerase binding ; GO:0000990 | contributes_to inferred by curator from GO:0005675 helicase activity ; GO:0004386 | inferred from sequence or structural similarity ATP-dependent 5'-3' DNA helicase activity ; GO:0043141 | inferred from sequence or structural similarity with SGD:S000000973" transcriptional open complex formation at RNA polymerase II promoter ; GO:0001113 | inferred from sequence or structural similarity with HGNC:3434 response to UV ; GO:0009411 | inferred from direct assay regulation of syncytial blastoderm mitotic cell cycle ; GO:0007348 | inferred from mutant phenotype promoter clearance from RNA polymerase II promoter ; GO:0001111 | inferred from sequence or structural similarity with HGNC:3434 nucleotide-excision repair ; GO:0006289 | inferred from sequence or structural similarity with HGNC:3434 inferred from sequence or structural similarity with SGD:S000000973 regulation of chromosome segregation ; GO:0051983 | inferred from mutant phenotype transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:3434 inferred from sequence or structural similarity with SGD:S000000973 negative regulation of G2/M transition of mitotic cell cycle ; GO:0010972 | inferred from direct assay response to UV ; GO:0009411 | inferred from mutant phenotype regulation of mitotic nuclear division ; GO:0007088 | inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from direct assay "polytene chromosome interband ; GO:0005705 | inferred from direct assay core TFIIH complex ; GO:0000439 | inferred from sequence or structural similarity with HGNC:3434 cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay holo TFIIH complex ; GO:0005675 | inferred from physical interaction with hay, CycH, Mat1, mrn, Cdk7 holo TFIIH complex ; GO:0005675 | inferred from sequence or structural similarity with SGD:S000000973 polytene chromosome puff ; GO:0005703 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay core TFIIH complex ; GO:0000439 | inferred from direct assay holo TFIIH complex ; GO:0005675 | inferred from sequence or structural similarity with HGNC:3434 inferred from sequence or structural similarity with SGD:S000000973" "Xpd, l(2)SH2137, xpd, XPD, XPD/ERCC2, CG9433, DmXPD, DhXPD, DhR3, ERCC2, l(2)SH2 2137" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR001945:RAD3/XPD family, IPR002464:DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site, IPR006554:Helicase-like, DEXD box c2 type, IPR006555:ATP-dependent helicase, C-terminal, IPR010643:Helical and beta-bridge domain, IPR013020:DNA helicase (DNA repair), Rad3 type, IPR014013:Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type, IPR010614:DEAD2" CG9433 27-Aug-18 DroID_v2018_08 Drer\ercc2 Scer\RAD3 "Cele\Y50D7A.11, Cele\xpd-1" Xtro\ercc2 Mmus\Ercc2 Hsap\ERCC2 " embryonic stage | syncytial blastoderm , larval stage | third instar , embryonic stage | stage 5 , embryonic stage | stage >5 " "

ubiquitous , larval salivary gland

,

, embryonic/larval fat body

" FBgn0003188 qui quit http://flybase.org/reports/FBgn0003188 - gene molecular_function ; GO:0003674 | no biological data available ovarian follicle cell migration ; GO:0007297 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available qui - - 27-Aug-18 DroID_v2018_08 - - - - - - female sterile "nurse follicle cell,ovary" FBgn0017420 su(RpII215)S3 su(RpII215)S3 http://flybase.org/reports/FBgn0017420 - gene - - - "S3, anon-S3/S13, su(RpII215)S3" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038248 CG7886 - http://flybase.org/reports/FBgn0038248 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available centrosome ; GO:0005813 | inferred from biological aspect of ancestor with PANTHER:PTN001189119 centrosome ; GO:0005813 | inferred from sequence or structural similarity with HGNC:25740 "anon-WO0140519.200, CG7886" "IPR032675:Leucine-rich repeat domain, L domain-like, IPR026212:Centrosomal protein of 78kDa" CG7886 27-Aug-18 DroID_v2018_08 "Drer\nod1, Drer\si:ch211-81a5.5, Drer\nlrx1, Drer\tonsl, Drer\si:dkey-23k10.3, Drer\lrrc34, Drer\nlrc3l, Drer\si:ch211-122c9.5, Drer\nod2, Drer\lrrc45, Drer\LOC101884653, Drer\cep78, Drer\nlrc3, Drer\ciita" - - "Xtro\nlrx1, Xtro\LOC100485518, Xtro\cep78, Xtro\lrrc31, Xtro\lrrc34, Xtro\tonsl, Xtro\lrrc45, Xtro\nod1" "Mmus\Cep78, Mmus\Lrrc74b, Mmus\Nlrp9c, Mmus\Nlrp4f, Mmus\Tonsl, Mmus\Lrrc71, Mmus\Lrrc74a, Mmus\Nod2, Mmus\Nlrc3, Mmus\Lrrc45, Mmus\Nlrp4c, Mmus\Nlrx1, Mmus\Ciita, Mmus\Nod1, Mmus\Nlrp4a, Mmus\Nlrp9a, Mmus\Lrrc34, Mmus\Nlrp14, Mmus\Nlrp4e, Mmus\Nlrp9b, Mmus\Lrrc31, Mmus\Rnh1" "Hsap\NOD2, Hsap\LRRC71, Hsap\LRRC74A, Hsap\CEP78, Hsap\NOD1, Hsap\TONSL, Hsap\LRRC45, Hsap\NLRP4, Hsap\NLRC5, Hsap\LRRC31, Hsap\CIITA, Hsap\NLRX1, Hsap\LRRC34, Hsap\NLRP14, Hsap\RNH1, Hsap\NLRP9" viable FBgn0013570 l(3)78Da lethal (3) 78Da http://flybase.org/reports/FBgn0013570 - gene - - - l(3)78Da - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0084254 E-3c4 Enhancer on chromosome 3-complementation group c4 http://flybase.org/reports/FBgn0084254 gene - - - "E-3c, E-3c4" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0259998 CG17571 - http://flybase.org/reports/FBgn0259998 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "CG17571, anon-38C.22, SP83, 38C.22" "IPR018114:Serine proteases, trypsin family, histidine active site, IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG17571 27-Aug-18 DroID_v2018_08 "Drer\zgc:123295, Drer\LOC562139, Drer\tmprss4b, Drer\zgc:163079, Drer\zgc:55888, Drer\prss60.3, Drer\ctrl, Drer\si:dkeyp-93a5.2, Drer\prss60.1, Drer\zgc:153968, Drer\prss60.2, Drer\zgc:92590, Drer\zgc:112160, Drer\try, Drer\zgc:112038" - "Cele\rab-11.1, Cele\svh-1, Cele\try-1" - "Mmus\Prss3, Mmus\Gm10334, Mmus\Try10, Mmus\Prss42, Mmus\2210010C04Rik, Mmus\Try4, Mmus\Prss2, Mmus\Prss1, Mmus\Ctrl, Mmus\Gm5771, Mmus\Prss34" "Hsap\PRSS1, Hsap\PRSS42, Hsap\CTRL, Hsap\PRSS3" DRSC01768 K 0.016076789 -0.063012137 -0.420297006 -0.048181006 -0.242862419 1.550058018 FBgn0033000 CG14464 - http://flybase.org/reports/FBgn0033000 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG40285, BcDNA:LD29015, CG14464" "IPR029264:ARF7 effector protein, C-terminal, IPR026515:ARL14 effector protein" CG14464 27-Aug-18 DroID_v2018_08 Drer\arl14ep - Cele\B0336.5 "Xtro\arl14epl, Xtro\arl14ep" "Mmus\Thap7, Mmus\Arl14ep, Mmus\Arl14epl" "Hsap\THAP7, Hsap\THAP8, Hsap\ARL14EP, Hsap\ARL14EPL" FBgn0022365 Pt-7A Adult protein-7A http://flybase.org/reports/FBgn0022365 - gene - - - Pt-7A - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039284 CG13652 - http://flybase.org/reports/FBgn0039284 protein_coding_gene - - - CG13652 - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible" "tormogen cell,mesothoracic tergum" FBgn0060654 l(3)S083005b lethal (3) S083005b http://flybase.org/reports/FBgn0060654 gene - - - "0830/05, l(3)S083005b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0260059 2L1749 - http://flybase.org/reports/FBgn0260059 gene - - - 2L1749 - - 27-Aug-18 DroID_v2018_08 - - - - - - "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0043573 S(faf)244 S(faf)244 http://flybase.org/reports/FBgn0043573 gene - - - S(faf)244 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033283 CG11635 - http://flybase.org/reports/FBgn0033283 protein_coding_gene - - - CG11635 "IPR006611:Protein of unknown function DUF1431, cysteine-rich, Drosophila" CG11635 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266048 lncRNA:CR44813 - http://flybase.org/reports/FBgn0266048 non_protein_coding_gene - - - "CR44813, lincRNA.390" - CR44813 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030976 CG7378 - http://flybase.org/reports/FBgn0030976 protein_coding_gene "protein tyrosine phosphatase activity ; GO:0004725 | inferred from electronic annotation with InterPro:IPR016130 protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | inferred from electronic annotation with InterPro:IPR000340, InterPro:IPR020405, InterPro:IPR020417, InterPro:IPR020422 protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | non-traceable author statement" "protein dephosphorylation ; GO:0006470 | inferred from electronic annotation with InterPro:IPR000340, InterPro:IPR020405, InterPro:IPR020417, InterPro:IPR020422 protein dephosphorylation ; GO:0006470 | non-traceable author statement" cellular_component ; GO:0005575 | no biological data available "BcDNA:RH25447, CG7378, MKP-like" "IPR000340:Dual specificity phosphatase, catalytic domain, IPR000387:Tyrosine specific protein phosphatases domain, IPR016130:Protein-tyrosine phosphatase, active site, IPR020405:Atypical dual specificity phosphatase, subfamily A, IPR020417:Atypical dual specificity phosphatase, IPR020422:Dual specificity protein phosphatase domain, IPR024950:Dual specificity phosphatase, IPR029021:Protein-tyrosine phosphatase-like" CG7378 27-Aug-18 DroID_v2018_08 "Drer\dusp16, Drer\dupd1, Drer\dusp10, Drer\si:ch211-203d1.3, Drer\dusp7, Drer\si:ch211-195b15.8, Drer\dusp3a, Drer\dusp19b, Drer\dusp13a, Drer\si:ch211-223p8.8, Drer\dusp12, Drer\dusp14, Drer\dusp19a, Drer\si:dkey-175m17.7, Drer\dusp22a, Drer\dusp1, Drer\zgc:153981, Drer\dusp2, Drer\dusp27, Drer\styx, Drer\zgc:153044, Drer\dusp6, Drer\dusp8b, Drer\dusp8a, Drer\si:ch1073-184j22.2, Drer\styxl1, Drer\ssh2a, Drer\dusp26, Drer\ssh1a, Drer\dusp5, Drer\dusp22b, Drer\dusp3b, Drer\si:ch211-121a2.2, Drer\ssh1b, Drer\dusp4, Drer\ssh2b" "Scer\MSG5, Scer\SDP1, Scer\YVH1, Scer\PPS1" "Cele\F13D11.3, Cele\lip-1, Cele\Y54F10BM.13, Cele\W09H1.1, Cele\F26A3.4, Cele\C04F12.8, Cele\C16A3.2" "Xtro\dusp19, Xtro\dusp4, Xtro\dusp22, Xtro\dusp22a, Xtro\dusp9, Xtro\epm2a, Xtro\dusp5, Xtro\styx, Xtro\ssh1, Xtro\dupd1, Xtro\ssh2, Xtro\dusp1, Xtro\dusp6, Xtro\dusp12, Xtro\dusp18, Xtro\styxl1, Xtro\dusp26, Xtro\dusp10" "Mmus\Styx, Mmus\Ssh2, Mmus\Dusp4, Mmus\Dusp6, Mmus\Dusp8, Mmus\Dusp19, Mmus\Dusp16, Mmus\Dusp13, Mmus\Dusp3, Mmus\Dusp18, Mmus\Epm2a, Mmus\Dusp7, Mmus\Dupd1, Mmus\Styxl1, Mmus\Dusp2, Mmus\Dusp14, Mmus\Ssh1, Mmus\Ssh3, Mmus\Dusp27, Mmus\Dusp5, Mmus\Dusp15, Mmus\Dusp9, Mmus\Dusp1, Mmus\Dusp10, Mmus\Dusp12, Mmus\Dusp22, Mmus\Dusp26, Mmus\Dusp21" "Hsap\DUSP1, Hsap\DUSP6, Hsap\DUSP27, Hsap\SSH2, Hsap\DUSP9, Hsap\DUSP21, Hsap\EPM2A, Hsap\SSH1, Hsap\DUSP15, Hsap\SSH3, Hsap\DUPD1, Hsap\DUSP12, Hsap\DUSP22, Hsap\DUSP26, Hsap\DUSP4, Hsap\DUSP18, Hsap\STYX, Hsap\DUSP16, Hsap\DUSP19, Hsap\DUSP8, Hsap\DUSP3, Hsap\DUSP13, Hsap\STYXL1, Hsap\DUSP7, Hsap\DUSP2, Hsap\DUSP5, Hsap\DUSP10" viable FBgn0002050 l(2)37Fc lethal (2) 37Fc http://flybase.org/reports/FBgn0002050 - gene - - - "l(2)E42, l(2)37Fc" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0021834 l(2)k15817 lethal (2) k15817 http://flybase.org/reports/FBgn0021834 - gene - - - l(2)k15817 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0065526 l(2)SH1118 lethal (2) SH1118 http://flybase.org/reports/FBgn0065526 gene - - - "l(2)SH1118, l(2)SH2 1118" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0259585 B2030 - http://flybase.org/reports/FBgn0259585 gene - - - B2030 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible metathoracic leg FBgn0020255 Ran Ran http://flybase.org/reports/FBgn0020255 "FBgn0026685, FBgn0030273" protein_coding_gene GTPase activity ; GO:0003924 | inferred from biological aspect of ancestor with PANTHER:PTN000632582 protein binding ; GO:0005515 | inferred from physical interaction with cno GTP binding ; GO:0005525 | inferred from direct assay GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with SGD:S000005711 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9W1A4 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR002041 actin filament organization ; GO:0007015 | inferred from mutant phenotype establishment of mitotic spindle orientation ; GO:0000132 | inferred from mutant phenotype inferred from genetic interaction with dlg1 inferred from genetic interaction with cno regulation of mitotic cell cycle ; GO:0007346 | inferred from direct assay protein import into nucleus ; GO:0006606 | inferred from biological aspect of ancestor with PANTHER:PTN000632582 meiotic spindle organization ; GO:0000212 | inferred from mutant phenotype cell adhesion ; GO:0007155 | inferred from mutant phenotype cellular response to starvation ; GO:0009267 | inferred from expression pattern cell cycle ; GO:0007049 | inferred from direct assay regulation of protein localization ; GO:0032880 | inferred from mutant phenotype protein export from nucleus ; GO:0006611 | inferred from sequence or structural similarity with HGNC:9846 regulation of cell shape ; GO:0008360 | inferred from mutant phenotype neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype ribosomal subunit export from nucleus ; GO:0000054 | inferred from biological aspect of ancestor with PANTHER:PTN000632582 intracellular protein transport ; GO:0006886 | traceable author statement microtubule associated complex ; GO:0005875 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay mitotic spindle ; GO:0072686 | inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay nuclear microtubule ; GO:0005880 | inferred from direct assay "Ran, AAF30287, CG1404, ran10A, dran, l(1)G0075, ran, Q9VZ23, RanGTP" "IPR002041:Ran GTPase, IPR005225:Small GTP-binding protein domain, IPR001806:Small GTPase superfamily, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG1404 27-Aug-18 DroID_v2018_08 Drer\ran "Scer\GSP1, Scer\GSP2" Cele\ran-1 Xtro\ran "Mmus\1700009N14Rik, Mmus\Rasl2-9, Mmus\Ran" Hsap\RAN embryonic stage organism

"viable,wild-type,female sterile,male sterile,lethal,fertile,partially lethal - majority die,recessive,lethal - all die before end of P-stage,some die during pharate adult stage,visible,lethal - all die before end of larval stage,some die during larval stage" "karyosome,meiotic spindlenos.UTR.THsimVP16,ommatidium,photoreceptor cell,photoreceptor cell R7,cone cell,pigment cell" DRSC20364 I -1.583757533 0.054210938 -1.360761974 -0.590233519 0.303333163 0.629600729 FBgn0050021 metro menage a trois http://flybase.org/reports/FBgn0050021 protein_coding_gene - neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype regulation of synaptic growth at neuromuscular junction ; GO:0008582 | inferred from mutant phenotype subsynaptic reticulum ; GO:0071212 | inferred from direct assay "CG18338, CG13219, CG30021, Metro, metro, skf, FBgn0050021, skiff" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR001452:SH3 domain, IPR001478:PDZ domain, IPR004172:L27 domain, IPR008144:Guanylate kinase-like domain, IPR008145:Guanylate kinase/L-type calcium channel beta subunit, IPR011511:Variant SH3 domain, IPR020590:Guanylate kinase, conserved site" CG30021 27-Aug-18 DroID_v2018_08 "Drer\LOC556594, Drer\si:ch73-272h16.4, Drer\mpp3a, Drer\caska, Drer\mpp3b, Drer\mpp5b, Drer\mpp2b, Drer\mpp5a, Drer\mpp6a, Drer\mpp1, Drer\mpp4a, Drer\mpp7a, Drer\mpp2a, Drer\mpp7b, Drer\mpp6b" Scer\GUK1 "Cele\magu-1, Cele\lin-2, Cele\magu-2" "Xtro\mpp2, Xtro\mpp6, Xtro\cask, Xtro\mpp1, Xtro\mpp7, Xtro\mpp5" "Mmus\Mpp5, Mmus\Mpp3, Mmus\Cask, Mmus\Mpp7, Mmus\Mpp6, Mmus\Mpp2, Mmus\Mpp1, Mmus\Mpp4" "Hsap\MPP4, Hsap\MPP3, Hsap\CASK, Hsap\MPP7, Hsap\MPP1, Hsap\MPP6, Hsap\MPP2, Hsap\MPP5" "viable,fertile,neuroanatomy defective" neuromuscular junction FBgn0086666 snoRNA:Psi28S-2179 snoRNA:Psi28S-2179 http://flybase.org/reports/FBgn0086666 snoRNA_gene - - - "snoRNA:734, psi28S-2179, Dm-734, snoR734, CR33918, Psi28S-2719(SnoR734), SnoR734, Psi28S-2719, snoRNA:Psi28S-2179" - CR33918 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0015918 cant cat of nine tails http://flybase.org/reports/FBgn0015918 - gene - - - cant - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0086392 BG02053 - http://flybase.org/reports/FBgn0086392 gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - BG02053 - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,smell perception defective" FBgn0000386 ctt contorted http://flybase.org/reports/FBgn0000386 - gene - - - ctt - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive,female sterile,male fertile" "wing,eye,macrochaeta,anterior orbital bristle,middle orbital bristle,posterior orbital bristle,genitalia,male,orbital bristle,male genitalia" FBgn0014378 raz razorback http://flybase.org/reports/FBgn0014378 - gene - - - raz - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0015554 ttp tip-tap http://flybase.org/reports/FBgn0015554 - gene - - - ttp - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001350 l(1)1Ee lethal (1) 1Ee http://flybase.org/reports/FBgn0001350 - gene - - - l(1)1Ee - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0265946 lncRNA:CR44733 - http://flybase.org/reports/FBgn0265946 non_protein_coding_gene - - - CR44733 - CR44733 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0069224 gl(2R)18-14 gl(2R)18-14 http://flybase.org/reports/FBgn0069224 gene molecular_function ; GO:0003674 | no biological data available segment specification ; GO:0007379 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available gl(2R)18-14 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,germline clone,maternal effect,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" "embryonic segment,germline clone,maternal effect,embryonic head,denticle belt" FBgn0033782 sug sugarbabe http://flybase.org/reports/FBgn0033782 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 "negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from sequence or structural similarity with UniProtKB:Q8VDL9 positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from sequence or structural similarity with UniProtKB:Q8VDL9 insulin-like growth factor receptor signaling pathway ; GO:0048009 | inferred from mutant phenotype response to starvation ; GO:0042594 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay cellular response to nutrient ; GO:0031670 | inferred from direct assay" nuclear speck ; GO:0016607 | inferred from sequence or structural similarity with UniProtKB:Q8VDL9 "CG3850, sug" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG3850 27-Aug-18 DroID_v2018_08 "Drer\glis2a, Drer\glis2b, Drer\glis3, Drer\aaas, Drer\LOC100333406" "Scer\YPR015C, Scer\CMR3" "Cele\ztf-14, Cele\ref-2" "Xtro\glis2, Xtro\aaas, Xtro\glis3" "Mmus\Prdm5, Mmus\Glis1, Mmus\Glis2, Mmus\Aaas" "Hsap\AAAS, Hsap\ZKSCAN5, Hsap\GLIS2, Hsap\GLIS3, Hsap\GLIS1" "developmental rate defective,heat sensitive,lethal,male,starvation stress response defective,viable" FBgn0265718 lncRNA:CR44525 - http://flybase.org/reports/FBgn0265718 non_protein_coding_gene - - - "incRNA.462, CR44525, lincRNA.462" - CR44525 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039647 jus - http://flybase.org/reports/FBgn0039647 protein_coding_gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - "CG14510, CG14509" - CG14509 27-Aug-18 DroID_v2018_08 - - - - - - "viable,smell perception defective,fertile" FBgn0259467 C166 - http://flybase.org/reports/FBgn0259467 gene - - - C166 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing hair,wing vein" FBgn0002494 l(3)SG54 lethal (3) SG54 http://flybase.org/reports/FBgn0002494 - gene - - - l(3)SG54 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,heat sensitive,some die during embryonic stage" FBgn0002823 ms(2)38C male sterile (2) 38C http://flybase.org/reports/FBgn0002823 - gene - - - "ms, ms(2)38C" - - 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,recessive" FBgn0065637 l(2)SH0765 lethal (2) SH0765 http://flybase.org/reports/FBgn0065637 gene - - - "l(2)SH0765, l(2)SH2 0765" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0014340 mof males absent on the first http://flybase.org/reports/FBgn0014340 - protein_coding_gene "chromatin binding ; GO:0003682 | inferred from direct assay mRNA binding ; GO:0003729 | traceable author statement histone acetyltransferase activity (H4-K16 specific) ; GO:0046972 | traceable author statement histone acetyltransferase activity ; GO:0004402 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with nsl1 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor ; GO:0004468 | traceable author statement histone acetyltransferase activity ; GO:0004402 | inferred from direct assay histone acetyltransferase activity (H4-K16 specific) ; GO:0046972 | inferred from mutant phenotype histone acetyltransferase activity ; GO:0004402 | inferred from sequence or structural similarity with SGD:S000000148 inferred from sequence or structural similarity with SGD:S000004734" "dosage compensation by hyperactivation of X chromosome ; GO:0009047 | non-traceable author statement histone H4-K16 acetylation ; GO:0043984 | inferred from mutant phenotype negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype DNA repair ; GO:0006281 | inferred from mutant phenotype DNA damage checkpoint ; GO:0000077 | inferred from mutant phenotype histone acetylation ; GO:0016573 | traceable author statement positive regulation of sequence-specific DNA binding transcription factor activity ; GO:0051091 | inferred from mutant phenotype response to ionizing radiation ; GO:0010212 | inferred from mutant phenotype peptidyl-lysine acetylation ; GO:0018394 | traceable author statement regulation of histone H4 acetylation involved in response to DNA damage stimulus ; GO:2000873 | inferred from mutant phenotype dosage compensation ; GO:0007549 | inferred from mutant phenotype inferred from genetic interaction with msl-2 cellular response to ionizing radiation ; GO:0071479 | inferred from mutant phenotype DNA damage response, signal transduction by p53 class mediator ; GO:0030330 | inferred from mutant phenotype" "MSL complex ; GO:0072487 | inferred from direct assay X chromosome located dosage compensation complex, transcription activating ; GO:0016456 | non-traceable author statement nucleus ; GO:0005634 | inferred from direct assay X chromosome ; GO:0000805 | traceable author statement X chromosome located dosage compensation complex, transcription activating ; GO:0016456 | traceable author statement polytene chromosome interband ; GO:0005705 | inferred from direct assay X chromosome located dosage compensation complex, transcription activating ; GO:0016456 | inferred from direct assay transcription factor complex ; GO:0005667 | inferred from direct assay NSL complex ; GO:0044545 | inferred from direct assay nuclear chromosome ; GO:0000228 | inferred from direct assay" "MOF, CG3025, dMOF, dmMOF, Mof, max, mof" "IPR002717:Histone acetyltransferase domain, MYST-type, IPR016181:Acyl-CoA N-acyltransferase, IPR016197:Chromo domain-like, IPR025995:RNA binding activity-knot of a chromodomain" CG3025 27-Aug-18 DroID_v2018_08 "Drer\kat5a, Drer\kat6b, Drer\kat8, Drer\kat7b, Drer\kat7a, Drer\kat5b, Drer\kat6a" "Scer\ESA1, Scer\SAS3, Scer\SAS2" "Cele\mys-4, Cele\mys-1, Cele\mys-2" "Xtro\kat5, Xtro\trim69.1, Xtro\xnf7, Xtro\kat7, Xtro\kat8" "Mmus\Kat5, Mmus\Kat8, Mmus\Kat6a, Mmus\Kat7, Mmus\Kat6b" "Hsap\KAT5, Hsap\KAT8, Hsap\KAT6B, Hsap\KAT6A, Hsap\KAT7" larval stage--adult stage "female fertile,non-suppressor of variegation,wild-type,lethal,male,recessive,viable,female,increased cell death,radiation sensitive,partially lethal - majority die,female sterile,short lived,male limited,large body,female limited,decreased cell growth,lethal - all die during larval stage" "heart primordium,eye disc,wing disc,embryonic/larval fat body" FBgn0065259 l(2)SH2089 lethal (2) SH2089 http://flybase.org/reports/FBgn0065259 gene - - - l(2)SH2089 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0262107 asRNA:CR42860 - http://flybase.org/reports/FBgn0262107 non_protein_coding_gene - - - CR42860 - CR42860 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001598 l(1)CP8 lethal (1) CP8 http://flybase.org/reports/FBgn0001598 - gene - - - l(1)CP8 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0021843 l(2)k14816 lethal (2) k14816 http://flybase.org/reports/FBgn0021843 - gene - - - l(2)k14816 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0035799 CG14838 - http://flybase.org/reports/FBgn0035799 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - - CG14838 "IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG14838 27-Aug-18 DroID_v2018_08 Drer\wdr63 - Cele\pfs-2 "Xtro\wdr63, Xtro\LOC101732357" Mmus\Wdr63 Hsap\WDR63 "viable,fertile" FBgn0085398 ppk9 pickpocket 9 http://flybase.org/reports/FBgn0085398 protein_coding_gene sodium channel activity ; GO:0005272 | inferred from sequence or structural similarity with MGI:MGI:101782 sodium ion transport ; GO:0006814 | inferred from sequence or structural similarity with MGI:MGI:101782 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with MGI:MGI:101782 "CG13489, CG13490, ppk9, CG34369" IPR001873:Epithelial sodium channel CG34369 27-Aug-18 DroID_v2018_08 "Drer\asic1b, Drer\asic4a, Drer\asic2, Drer\asic1a, Drer\asic1c, Drer\asic4b" - "Cele\acd-1, Cele\flr-1, Cele\acd-4, Cele\del-7, Cele\delm-1, Cele\acd-2, Cele\delm-2, Cele\acd-3, Cele\acd-5" "Xtro\scnn1a, Xtro\asic5, Xtro\asic4, Xtro\scnn1d, Xtro\scnn1b, Xtro\scnn1g, Xtro\asic1" "Mmus\Scnn1b, Mmus\Asic4, Mmus\Asic2, Mmus\Asic3, Mmus\Asic5, Mmus\Scnn1a, Mmus\Asic1, Mmus\Scnn1g" "Hsap\SCNN1G, Hsap\SCNN1A, Hsap\SCNN1B, Hsap\ASIC3, Hsap\SCNN1D, Hsap\ASIC5, Hsap\ASIC1, Hsap\ASIC4, Hsap\ASIC2" DRSC04135 I 1.539440532 -1.736385215 -0.663016632 -1.327574442 -0.028808552 -0.56408249 FBgn0085252 CG34223 - http://flybase.org/reports/FBgn0085252 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34223 - CG34223 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034514 CG13427 - http://flybase.org/reports/FBgn0034514 protein_coding_gene - gastrulation ; GO:0007369 | inferred from expression pattern vesicle ; GO:0031982 | inferred from direct assay CG13427 - CG13427 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0070024 BG00488 BG00488 http://flybase.org/reports/FBgn0070024 gene - - - BG00488 - - 27-Aug-18 DroID_v2018_08 - - - - - - stress response defective FBgn0050201 tRNA:Ser-TGA-1-1 transfer RNA:Serine-TGA 1-1 http://flybase.org/reports/FBgn0050201 tRNA_gene UCA codon-amino acid adaptor activity ; GO:0033407 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033407 cytosol ; GO:0005829 | inferred by curator from GO:0033407 "CR30201, AE002575.trna9-SerTGA, tRNA:S:TGA:AE002575-b, tRNA[[Ser]], chr2R:18579596..18579746, chr2R.trna53-SerTGA, tRNA-Ser-TGA-1-1, tRNA:Ser-TGA-1-1, tRNA:CR30201, UCA" - CR30201 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0023110 anon-10Ax anon-10Ax http://flybase.org/reports/FBgn0023110 - gene - - - "17, anon-10Ax" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0043849 412\ORF1 412 element ORF1 http://flybase.org/reports/FBgn0043849 transposable_element_gene - - - "412\ORF1, ORF1" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031048 CG12237 - http://flybase.org/reports/FBgn0031048 protein_coding_gene pyrophosphatase activity ; GO:0016462 | inferred from sequence or structural similarity with HGNC:16815 phosphatase activity ; GO:0016791 | inferred from biological aspect of ancestor with PANTHER:PTN000467154 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG12237, 16769716" "IPR006384:Pyridoxal phosphate phosphatase-related, IPR016965:Phosphatase PHOSPHO-type, IPR023214:HAD-like domain" CG12237 27-Aug-18 DroID_v2018_08 "Drer\phospho2, Drer\phospho1" - "Cele\irld-49, Cele\irld-51, Cele\irld-56, Cele\irld-67, Cele\irld-60, Cele\irld-64, Cele\irld-39, Cele\hpa-1" Xtro\phospho2 "Mmus\Phospho2, Mmus\Phospho1" "Hsap\PHOSPHO1, Hsap\PHOSPHO2" FBgn0029730 boil boilerman http://flybase.org/reports/FBgn0029730 protein_coding_gene molecular_function ; GO:0003674 | no biological data available detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG12681, boil" IPR031732:Protein of unknown function DUF4729 CG12681 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0028945 CG7631 - http://flybase.org/reports/FBgn0028945 protein_coding_gene metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR001506 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR006026 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001506, InterPro:IPR006026 lateral inhibition ; GO:0046331 | inferred from mutant phenotype" - "BG:BACR44L22.6, CG7631" "IPR001506:Peptidase M12A, IPR006026:Peptidase, metallopeptidase, IPR024079:Metallopeptidase, catalytic domain, IPR034035:Astacin-like metallopeptidase domain" CG7631 27-Aug-18 DroID_v2018_08 "Drer\LOC100003133, Drer\LOC797085, Drer\c6ast3, Drer\npsnl, Drer\mep1a.1, Drer\bmp1a, Drer\npsn, Drer\bmp1b, Drer\mep1a.2, Drer\tnfaip6, Drer\he2, Drer\c6ast1, Drer\c6ast4, Drer\si:ch73-40a17.3, Drer\mep1b, Drer\he1b, Drer\he1a, Drer\tll1" - "Cele\nas-6, Cele\nas-4, Cele\nas-39, Cele\nas-13, Cele\Y19D10A.6, Cele\nas-8, Cele\nas-14, Cele\nas-15, Cele\nas-2, Cele\nas-7, Cele\nas-12, Cele\nas-1, Cele\ZC116.3" "Xtro\mep1b, Xtro\bmp1, Xtro\uvs.2, Xtro\accs, Xtro\LOC100492324, Xtro\tll1, Xtro\LOC100489456, Xtro\tll2, Xtro\tnfaip6, Xtro\cubn, Xtro\mep1a" "Mmus\Mep1a, Mmus\Cubn, Mmus\Tll2, Mmus\Adgrg6, Mmus\Tnfaip6, Mmus\Astl, Mmus\Mep1b, Mmus\Tll1, Mmus\Bmp1" "Hsap\ASTL, Hsap\ADGRG6, Hsap\TNFAIP6, Hsap\MEP1B, Hsap\BMP1, Hsap\MEP1A, Hsap\TLL1, Hsap\TLL2, Hsap\CUBN" "viable,visible" "chaeta,supernumerary" FBgn0261566 CG42680 - http://flybase.org/reports/FBgn0261566 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42680 - CG42680 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265723 lncRNA:CR44530 - http://flybase.org/reports/FBgn0265723 non_protein_coding_gene - - - "incRNA.420, CR44530, lincRNA.420" - CR44530 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0019878 anon-69Ae anon-69Ae http://flybase.org/reports/FBgn0019878 - gene - - - anon-69Ae - - 27-Aug-18 DroID_v2018_08 - - - - - - larval stage FBgn0034139 CG4927 - http://flybase.org/reports/FBgn0034139 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP42, CG4927" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG4927 27-Aug-18 DroID_v2018_08 - - Cele\svh-1 - "Mmus\Prss12, Mmus\F12, Mmus\Plat, Mmus\Hgfac, Mmus\Plau, Mmus\Habp2" Hsap\MASP1 "viable,fertile" DRSC06903 I 1.700280649 -0.04912185 -1.071771863 -0.039939986 0.846974055 -0.144782249 FBgn0038943 CG5391 - http://flybase.org/reports/FBgn0038943 protein_coding_gene - - - CG5391 - CG5391 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0000002 5SrRNA 5S ribosomal RNA http://flybase.org/reports/FBgn0000002 FBgn0010528 rRNA_gene - - cytosolic large ribosomal subunit ; GO:0022625 | non-traceable author statement "5S RNA, 5S rRNA, 5SrDNA, 5S-rDNA, 5SRNA, 5S rDNA, 5S, 2S rRNA, l(2)03068, PZ03068, RNA X, Dm5S, 5SrRNA, rRNA, 5S_DM" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,lethal,recessive" FBgn0261458 capt capulet http://flybase.org/reports/FBgn0261458 protein_coding_gene actin binding ; GO:0003779 | inferred from biological aspect of ancestor with PANTHER:PTN000068843 actin binding ; GO:0003779 | inferred from sequence or structural similarity adenylate cyclase binding ; GO:0008179 | inferred from sequence or structural similarity with PomBase:SPCC306.09c adenylate cyclase binding ; GO:0008179 | inferred from biological aspect of ancestor with PANTHER:PTN000068843 photoreceptor cell axon guidance ; GO:0072499 | inferred from mutant phenotype regulation of adenylate cyclase activity ; GO:0045761 | inferred from biological aspect of ancestor with PANTHER:PTN000068843 actin filament organization ; GO:0007015 | inferred from mutant phenotype chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype cell morphogenesis ; GO:0000902 | inferred from mutant phenotype actin polymerization or depolymerization ; GO:0008154 | inferred from mutant phenotype rhabdomere development ; GO:0042052 | inferred from mutant phenotype muscle cell cellular homeostasis ; GO:0046716 | inferred from genetic interaction with Dys oogenesis ; GO:0048477 | inferred from mutant phenotype signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000068843 oocyte microtubule cytoskeleton polarization ; GO:0008103 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay cortical actin cytoskeleton ; GO:0030864 | inferred from biological aspect of ancestor with PANTHER:PTN000068843 "capt, CG5061, CG33979, cyclase-associated protein, capping protein, CAP, Cap, acu, cap, Capt, Acap, l(2)06955, Dcap, CG5074, BcDNA:LD24380, punc, CP" "IPR001837:Adenylate cyclase-associated CAP, IPR003124:WH2 domain, IPR006599:CARP motif, IPR013912:Adenylate cyclase-associated CAP, C-terminal, IPR013992:Adenylate cyclase-associated CAP, N-terminal, IPR017901:C-CAP/cofactor C-like domain, IPR028417:CAP, conserved site, C-terminal" CG33979 27-Aug-18 DroID_v2018_08 "Drer\cap2, Drer\cap1" Scer\SRV2 "Cele\cas-1, Cele\cas-2, Cele\Y65B4A.4" "Xtro\cap2, Xtro\cap1" "Mmus\Cap1, Mmus\Cap2" "Hsap\CAP1, Hsap\CAP2" FBgn0050439 CG30439 - http://flybase.org/reports/FBgn0050439 protein_coding_gene - - - CG30439 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0053504 snRNA:U7 small nuclear RNA U7 http://flybase.org/reports/FBgn0053504 snRNA_gene mRNA binding ; GO:0003729 | inferred from direct assay histone mRNA metabolic process ; GO:0008334 | inferred from direct assay mRNA 3'-end processing by stem-loop binding and cleavage ; GO:0006398 | inferred from mutant phenotype oocyte development ; GO:0048599 | inferred from mutant phenotype nuclear body ; GO:0016604 | inferred from direct assay cytoplasmic U snRNP body ; GO:0071254 | inferred from direct assay histone locus body ; GO:0035363 | inferred from direct assay U7 snRNP ; GO:0005683 | inferred from direct assay "U7 snRNA, CR33504, snRNA:U7, U7, U7snRNA, 63E-F U7" - CR33504 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,recessive,female sterile,viable" FBgn0065252 l(2)SH2114 lethal (2) SH2114 http://flybase.org/reports/FBgn0065252 gene - - - "l(2)SH2114, l(2)SH2 2114" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0063915 McClintock\pol McClintock element pol http://flybase.org/reports/FBgn0063915 transposable_element_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR012337 DNA integration ; GO:0015074 | inferred from electronic annotation with InterPro:IPR001584 - McClintock\pol "IPR000477:Reverse transcriptase domain, IPR001584:Integrase, catalytic core, IPR012337:Ribonuclease H-like domain" - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004111 opa-e opa repeat http://flybase.org/reports/FBgn0004111 - repeat_region - - - "opa, CAX repeat, strep, CAX, M-repeat, M, opa-e" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0016678 Mab13G5 Monoclonal antibody 13G5 http://flybase.org/reports/FBgn0016678 - gene - - - Mab13G5 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0046121 E(To)4 E(To)4 http://flybase.org/reports/FBgn0046121 gene - - - E(To)4 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0036958 CG17233 - http://flybase.org/reports/FBgn0036958 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG6918, CG17233" "IPR025451:Domain of unknown function DUF4211, IPR011989:Armadillo-like helical, IPR015943:WD40/YVTN repeat-like-containing domain" CG17233 27-Aug-18 DroID_v2018_08 "Drer\ccdc82, Drer\qser1" - Cele\eor-2 - "Mmus\Prr12, Mmus\Qser1, Mmus\Ccdc82" "Hsap\QSER1, Hsap\PRR12, Hsap\CCDC82" "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0266308 lncRNA:CR44973 - http://flybase.org/reports/FBgn0266308 non_protein_coding_gene - - - CR44973 - CR44973 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001323 knrl knirps-like http://flybase.org/reports/FBgn0001323 - protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001628, InterPro:IPR013088 sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001628 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR001628" "open tracheal system development ; GO:0007424 | traceable author statement regulation of mitotic nuclear division ; GO:0007088 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay regulation of tube size, open tracheal system ; GO:0035151 | traceable author statement branched duct epithelial cell fate determination, open tracheal system ; GO:0046845 | traceable author statement epithelial cell migration, open tracheal system ; GO:0007427 | traceable author statement" nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR001628 "Knrl, NR0A2, CG4761, knrl, knl" "IPR001628:Zinc finger, nuclear hormone receptor-type, IPR013088:Zinc finger, NHR/GATA-type" CG4761 27-Aug-18 DroID_v2018_08 - - "Cele\nhr-119, Cele\nhr-3, Cele\nhr-85, Cele\nhr-7" - - Hsap\NR1H2 " embryonic stage | cellular blastoderm , embryonic stage , larval stage , embryonic stage | embryonic cycle 12 , larval stage | third instar , embryonic stage | 70% egg length , organism | 80-100% egg length & ventral

, wing vein L2 | precursor

,

ubiquitous , organism | 20-30% egg length

" "mitotic cell cycle defective,visible,viable" "dorsal closure embryo,embryonic dorsal epidermis,metathoracic femur,adult thorax & macrochaetaBx-MS1096" FBgn0263909 l(3)B57 - http://flybase.org/reports/FBgn0263909 gene - - - l(3)B57 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,decreased cell number,somatic clone" "embryonic/larval brain,somatic clone" FBgn0045968 Tabor\pol Tabor element pol http://flybase.org/reports/FBgn0045968 transposable_element_gene - - - "ORF2, Pilgrim\pol, Tabor\pol" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0003309 sable sable http://flybase.org/reports/FBgn0003309 - gene - developmental pigmentation ; GO:0048066 | traceable author statement developmental pigmentation ; GO:0048066 | non-traceable author statement - "eb, s, sable" - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive,body color defective,female sterile,viable,male,male fertile" "wing,scutellum,trident" FBgn0267928 lncRNA:CR46209 - http://flybase.org/reports/FBgn0267928 non_protein_coding_gene - - - "CR46209, lincRNA.196" - CR46209 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0067882 Mod(Prat:bw)1-5 Mod(Prat:bw)1-5 http://flybase.org/reports/FBgn0067882 gene - - - "Mod-1-5, Mod(Prat:bw)1-5" - - 27-Aug-18 DroID_v2018_08 - - - - - - enhancer of variegation FBgn0038965 mats mob as tumor suppressor http://flybase.org/reports/FBgn0038965 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9NBK5 protein kinase binding ; GO:0019901 | inferred from physical interaction with trc protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VA38 apoptotic process ; GO:0006915 | inferred from mutant phenotype chromosome segregation ; GO:0007059 | inferred from mutant phenotype signal transduction ; GO:0007165 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype cell proliferation ; GO:0008283 | inferred from mutant phenotype mitotic spindle checkpoint ; GO:0071174 | NOT inferred from mutant phenotype multicellular organism development ; GO:0007275 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "CG13852, anon-WO0118547.303, mats, Mats, DMob1, dmob1, Dmob1, Mob1" IPR005301:MOB kinase activator family CG13852 27-Aug-18 DroID_v2018_08 "Drer\mob2b, Drer\mob3c, Drer\mob2a, Drer\mob3a, Drer\mob1a, Drer\mob1ba, Drer\LOC799520, Drer\mob1bb" "Scer\MOB1, Scer\MOB2" "Cele\F38H4.10, Cele\T12B3.4" "Xtro\mob2.1, Xtro\mob3a, Xtro\mob3c, Xtro\mob2.2, Xtro\mob1a, Xtro\mob1b, Xtro\mob3b" "Mmus\Mob1a, Mmus\Mob1b, Mmus\Mob3b, Mmus\Mob3c, Mmus\Mob2, Mmus\Mob3a" "Hsap\MOB3C, Hsap\MOB2, Hsap\MOB3B, Hsap\MOB3A, Hsap\MOB1B, Hsap\MOB1A" "neuroanatomy defective,somatic clone,tumorigenic,dominant,lethal - all die before end of second instar larval stage,recessive,some die during second instar larval stage,lethal,visible,body color defective,viable,wild-type,mitotic cell cycle defective" "imaginal disc,adult mushroom body,somatic clone,humerus,anepisternum,denticle,wing,wing hair,supernumerary,trichogen cell,mesothoracic tergum" DRSC14702 K 0.085228639 0.658521368 0.285839586 0.376705118 -0.522239165 3.279516468 FBgn0266777 lncRNA:CR45242 - http://flybase.org/reports/FBgn0266777 non_protein_coding_gene - - - CR45242 - CR45242 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0013932 E(DTW) E(DTW) http://flybase.org/reports/FBgn0013932 - gene - - - E(DTW) - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085662 CG41517 - http://flybase.org/reports/FBgn0085662 protein_coding_gene - - - CG41517 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031108 CG15459 - http://flybase.org/reports/FBgn0031108 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available mitochondrial proton-transporting ATP synthase complex ; GO:0005753 | inferred from biological aspect of ancestor with PANTHER:PTN002145699 CG15459 - CG15459 27-Aug-18 DroID_v2018_08 Drer\si:dkeyp-80c12.10 - - - Mmus\Usmg5 Hsap\USMG5 FBgn0262683 CG43153 - http://flybase.org/reports/FBgn0262683 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43153, lincRNA.110" - CG43153 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051014 PH4alphaSG1 prolyl-4-hydroxylase-alpha SG1 http://flybase.org/reports/FBgn0051014 protein_coding_gene "procollagen-proline 4-dioxygenase activity ; GO:0004656 | inferred from electronic annotation with InterPro:IPR013547 L-ascorbic acid binding ; GO:0031418 | inferred from electronic annotation with InterPro:IPR006620 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen ; GO:0016702 | inferred from electronic annotation with InterPro:IPR013547 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR006620" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005123, InterPro:IPR006620, InterPro:IPR013547 salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype" endoplasmic reticulum ; GO:0005783 | inferred from direct assay "PHalphaSG1, CG15542, CG31014, PH4alphaSG1, SG1, Ph4alphaSG1, alphaSG1" "IPR005123:Oxoglutarate/iron-dependent dioxygenase, IPR006620:Prolyl 4-hydroxylase, alpha subunit, IPR013547:Prolyl 4-hydroxylase alpha-subunit, N-terminal, IPR011990:Tetratricopeptide-like helical domain" CG31014 27-Aug-18 DroID_v2018_08 "Drer\p4ha2, Drer\p4ha1b, Drer\zgc:158254, Drer\p4ha1a, Drer\p4ha3, Drer\p4htm, Drer\zgc:152670" - "Cele\phy-3, Cele\phy-4, Cele\phy-2, Cele\C14E2.4, Cele\dpy-18, Cele\Y43F8B.19" "Xtro\p4ha3, Xtro\p4ha1, Xtro\p4ha2" "Mmus\P4ha1, Mmus\P4ha3, Mmus\P4ha2, Mmus\P4htm" "Hsap\P4HA3, Hsap\P4HA2, Hsap\P4HTM, Hsap\P4HA1" viable FBgn0010563 l(2)04008 lethal (2) 04008 http://flybase.org/reports/FBgn0010563 - gene - - - l(2)04008 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0267204 lncRNA:CR45644 - http://flybase.org/reports/FBgn0267204 non_protein_coding_gene - - - CR45644 - CR45644 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085479 CG34450 - http://flybase.org/reports/FBgn0085479 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG34450, CG32705, CG12136" - CG34450 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005107 gustF gustatory-defective F http://flybase.org/reports/FBgn0005107 - gene - - - gustF - - 27-Aug-18 DroID_v2018_08 - - - - - - taste perception defective taste bristle FBgn0265300 lncRNA:CR44273 - http://flybase.org/reports/FBgn0265300 non_protein_coding_gene - - - CR44273 - CR44273 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000013 abd abdominal http://flybase.org/reports/FBgn0000013 - gene - sensory organ development ; GO:0007423 | non-traceable author statement - "a-3, a(3)26, abd" - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,semidominant" "tergite,sternite" FBgn0036427 CG4613 - http://flybase.org/reports/FBgn0036427 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP40, CG4613" "IPR001314:Peptidase S1A, chymotrypsin family, IPR001254:Serine proteases, trypsin domain, IPR018114:Serine proteases, trypsin family, histidine active site, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG4613 27-Aug-18 DroID_v2018_08 "Drer\si:dkeyp-93a5.2, Drer\si:ch211-165b19.9, Drer\zgc:112368, Drer\tmprss3a, Drer\prss60.1, Drer\zgc:112038, Drer\prss60.3, Drer\zgc:112160, Drer\tmprss4b, Drer\si:ch211-165b19.5, Drer\gzma, Drer\zgc:153968, Drer\si:ch211-165b19.8, Drer\zgc:171592, Drer\try, Drer\LOC100004427, Drer\zgc:165423, Drer\gzm3, Drer\zgc:112302, Drer\zgc:123295, Drer\ela2l, Drer\zgc:92590, Drer\cfd, Drer\zgc:92313, Drer\LOC562139, Drer\zgc:154142, Drer\si:dkeyp-93a5.3, Drer\ctrl, Drer\prss60.2, Drer\si:dkey-16l2.17, Drer\zgc:92511, Drer\zgc:92041, Drer\zgc:163079, Drer\si:dkey-238d18.3, Drer\gzmk, Drer\ela3l, Drer\si:dkey-57c15.4, Drer\zgc:112285, Drer\zgc:92745, Drer\ela2, Drer\ctrb1, Drer\ovch1" - "Cele\try-6, Cele\try-1" "Xtro\tmprss3, Xtro\ctrb1, Xtro\prss29, Xtro\LOC100135144, Xtro\cela2a, Xtro\ctrb2, Xtro\cela3a" "Mmus\Tmprss3, Mmus\Ctrb1, Mmus\Cela3a, Mmus\Try10, Mmus\Hpn, Mmus\Try4, Mmus\Gm5771, Mmus\Ctrc, Mmus\Prss34, Mmus\Ctrl, Mmus\Cela1, Mmus\2210010C04Rik, Mmus\Klk15, Mmus\Cela3b, Mmus\Tmprss5, Mmus\Prss1, Mmus\Prss2, Mmus\Klk9, Mmus\Cela2a, Mmus\Gm10334, Mmus\Prss3, Mmus\Tmprss2" "Hsap\CTRC, Hsap\CELA3B, Hsap\CTRL, Hsap\KLK9, Hsap\HPN, Hsap\CELA1, Hsap\KLK15, Hsap\TMPRSS3, Hsap\CELA3A, Hsap\PRSS3, Hsap\TMPRSS5, Hsap\CELA2A, Hsap\CELA2B, Hsap\CTRB1, Hsap\PRSS1, Hsap\TMPRSS2, Hsap\CTRB2" viable FBgn0051213 CG31213 - http://flybase.org/reports/FBgn0051213 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR017871 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from biological aspect of ancestor with PANTHER:PTN000442469 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from sequence or structural similarity with UniProtKB:O94911" lipid transport ; GO:0006869 | inferred from biological aspect of ancestor with PANTHER:PTN000442469 transport ; GO:0006810 | inferred from sequence or structural similarity with UniProtKB:O94911 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with UniProtKB:Q9BZC7 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000442469 "CG4794, CG11460, CG31213" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR003439:ABC transporter-like, IPR017871:ABC transporter, conserved site, IPR003593:AAA+ ATPase domain, IPR026082:ABC transporter A, ABCA" CG31213 27-Aug-18 DroID_v2018_08 "Drer\abch1, Drer\abca3b, Drer\abca2, Drer\abca12, Drer\abca5, Drer\abca1b, Drer\abca1a" - "Cele\abt-1, Cele\abt-4, Cele\ced-7, Cele\abt-2, Cele\abt-5" "Xtro\abca3, Xtro\abca4, Xtro\abca10, Xtro\abca1, Xtro\abca8, Xtro\abca9, Xtro\abca2" "Mmus\Abca16, Mmus\Abca8a, Mmus\Abca3, Mmus\Abca5, Mmus\Abca13, Mmus\Abca7, Mmus\Abca4, Mmus\Abca14, Mmus\Abca17, Mmus\Abca15, Mmus\Abca2, Mmus\Abca6, Mmus\Abca8b, Mmus\Abca12, Mmus\Abca9, Mmus\Abca1" "Hsap\ABCA13, Hsap\ABCA6, Hsap\ABCA5, Hsap\ABCA4, Hsap\ABCA2, Hsap\ABCA1, Hsap\ABCA7, Hsap\ABCA10, Hsap\ABCA9, Hsap\ABCA3, Hsap\ABCA12, Hsap\ABCA8" viable FBgn0265526 lncRNA:CR44376 - http://flybase.org/reports/FBgn0265526 non_protein_coding_gene - - - CR44376 - CR44376 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265533 CR44383 - http://flybase.org/reports/FBgn0265533 pseudogene_attribute - - - CR44383 - CR44383 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0062258 SF-1 SF1 boundary element http://flybase.org/reports/FBgn0062258 insulator - - - "SF1, SF-1" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004793 crpe crepe http://flybase.org/reports/FBgn0004793 - gene molecular_function ; GO:0003674 | no biological data available chorion-containing eggshell formation ; GO:0007304 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available crpe - - 27-Aug-18 DroID_v2018_08 - - - - - - female sterile FBgn0033498 CG12209 - http://flybase.org/reports/FBgn0033498 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "BcDNA:AT13439, CG12209" - CG12209 27-Aug-18 DroID_v2018_08 - Scer\BXI1 - - - - "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0084000 CG41433 - http://flybase.org/reports/FBgn0084000 protein_coding_gene - - - CG41433 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0014311 l(3)ry105 lethal (3) ry105 http://flybase.org/reports/FBgn0014311 FBgn0015507 gene - - - "P622, l(3)ry105" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0266749 lncRNA:CR45222 - http://flybase.org/reports/FBgn0266749 non_protein_coding_gene - - - CR45222 - CR45222 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0013500 l(1)MA lethal (1) MA http://flybase.org/reports/FBgn0013500 - gene - - - l(1)MA - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265962 lncRNA:CR44749 - http://flybase.org/reports/FBgn0265962 non_protein_coding_gene - - - CR44749 - CR44749 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0067786 anon-i176 anon-i176 http://flybase.org/reports/FBgn0067786 gene - - - "i176, anon-i176" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039339 CG5116 - http://flybase.org/reports/FBgn0039339 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR006073, InterPro:IPR016496, InterPro:IPR030394 ribosome binding ; GO:0043022 | inferred from biological aspect of ancestor with PANTHER:PTN000027640" - cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000027640 "CG5116, Dromel_CG5116_FBtr0084877_mORF" "IPR030394:HflX-type guanine nucleotide-binding (G) domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR016496:GTPase HflX, IPR006073:GTP binding domain, IPR025121:GTPase HflX, N-terminal, IPR032305:GTP-binding protein, middle domain" CG5116 27-Aug-18 DroID_v2018_08 Drer\gtpbp6 - Cele\F46B6.4 Xtro\gtpbp6 Mmus\Gtpbp6 Hsap\GTPBP6 viable FBgn0052850 CG32850 - http://flybase.org/reports/FBgn0052850 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:10056 ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN001021049 zinc ion binding ; GO:0008270 | inferred from sequence model protein autoubiquitination ; GO:0051865 | inferred from sequence or structural similarity with HGNC:10056 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN001021049 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from sequence or structural similarity with HGNC:10056 ubiquitin ligase complex ; GO:0000151 | inferred from sequence or structural similarity with HGNC:10056 "BEST:GH26713, BcDNA:RE41137, CG32850, RNF-11" "IPR001841:Zinc finger, RING-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG32850 27-Aug-18 DroID_v2018_08 "Drer\rnf126, Drer\rnf6, Drer\znrf3, Drer\rnf130, Drer\rnf111, Drer\rnf44, Drer\wu:fb39e10, Drer\rlim, Drer\pja2, Drer\rnf150a, Drer\rnf165b, Drer\si:ch211-81a5.1, Drer\rnf24, Drer\rnf11b, Drer\rnf32, Drer\si:dkey-51a16.9, Drer\rnf11a, Drer\zgc:175214, Drer\si:ch1073-392o20.1, Drer\rnf165a, Drer\rnf103, Drer\zswim2, Drer\rnf215, Drer\rnf150, Drer\rnf38, Drer\rnf115" "Scer\ASR1, Scer\YBR062C" "Cele\C01G6.4, Cele\eak-3" "Xtro\rnf44, Xtro\rnf111, Xtro\rnf11.2, Xtro\znrf3, Xtro\rnf126, Xtro\chmp3, Xtro\rnf38, Xtro\pja2, Xtro\rlim, Xtro\rnf115, Xtro\rnf24, Xtro\rnf11, Xtro\rnf181, Xtro\rnf149, Xtro\rnf32" "Mmus\Rnf181, Mmus\Rnf43, Mmus\Zswim2, Mmus\Znrf3, Mmus\Rnf24, Mmus\Rnf32, Mmus\Rnf115, Mmus\Rnf130, Mmus\Rnf126, Mmus\Rnf122, Mmus\Rnf149, Mmus\Rnf44, Mmus\Rnf38, Mmus\Rnf11, Mmus\Rnf111, Mmus\Rnf215, Mmus\Rnf165, Mmus\Rnf150, Mmus\Pja1, Mmus\Rlim, Mmus\Rnf6, Mmus\4930595M18Rik, Mmus\Pja2, Mmus\Rnf103" "Hsap\RNF32, Hsap\RNF215, Hsap\PJA1, Hsap\RNF149, Hsap\RNF181, Hsap\ZNRF3, Hsap\RNF111, Hsap\RLIM, Hsap\RNF24, Hsap\RNF43, Hsap\RNF115, Hsap\RNF165, Hsap\PJA2, Hsap\ZSWIM2, Hsap\RNF44, Hsap\RNF11, Hsap\RNF130, Hsap\RNF6, Hsap\CHMP3, Hsap\RNF38, Hsap\RNF122, Hsap\RNF103, Hsap\RNF126, Hsap\RNF150" "viable,fertile" FBgn0053758 CG33758 - http://flybase.org/reports/FBgn0053758 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33758 IPR010512:Protein of unknown function DUF1091 CG33758 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259654 B0960 - http://flybase.org/reports/FBgn0259654 gene - - - B0960 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing vein,wing,tarsal segment,unguis" FBgn0028879 CG15270 - http://flybase.org/reports/FBgn0028879 protein_coding_gene intracellular calcium activated chloride channel activity ; GO:0005229 | inferred from sequence or structural similarity with UniProtKB:Q9NW15 calcium activated cation channel activity ; GO:0005227 | inferred from sequence or structural similarity with HGNC:25519 chloride transport ; GO:0006821 | inferred from sequence or structural similarity with UniProtKB:Q9NW15 cation transport ; GO:0006812 | inferred from sequence or structural similarity with HGNC:25519 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with HGNC:25519 "BG:DS04929.1, CG15270" "IPR007632:Anoctamin, IPR015943:WD40/YVTN repeat-like-containing domain, IPR032675:Leucine-rich repeat domain, L domain-like" CG15270 27-Aug-18 DroID_v2018_08 "Drer\ano10a, Drer\ano10b, Drer\ano8b, Drer\ano8a, Drer\ano5a" Scer\IST2 "Cele\anoh-1, Cele\anoh-2" "Xtro\ano8, Xtro\ano10" "Mmus\Ano4, Mmus\Ano7, Mmus\Ano10, Mmus\Ano3, Mmus\Ano1, Mmus\Ano5, Mmus\Ano8" "Hsap\ANO5, Hsap\ANO10, Hsap\ANO8, Hsap\ANO4, Hsap\ANO7, Hsap\ANO1" viable FBgn0026669 l(1)G0129 lethal (1) G0129 http://flybase.org/reports/FBgn0026669 - gene - - - l(1)G0129 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0085319 CG34290 - http://flybase.org/reports/FBgn0085319 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - CG34290 "IPR001314:Peptidase S1A, chymotrypsin family, IPR001254:Serine proteases, trypsin domain, IPR018114:Serine proteases, trypsin family, histidine active site, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG34290 27-Aug-18 DroID_v2018_08 "Drer\LOC103908930, Drer\prss59.1, Drer\prss59.2, Drer\try, Drer\si:dkey-33m11.8, Drer\zgc:92590, Drer\LOC560023" - Cele\svh-1 "Xtro\LOC496746, Xtro\prss1, Xtro\prss1.2, Xtro\prss3, Xtro\try10, Xtro\prss2" "Mmus\Try10, Mmus\Prss1, Mmus\Prss2, Mmus\Gm2663, Mmus\1810009J06Rik, Mmus\Prss3, Mmus\Try5, Mmus\2210010C04Rik, Mmus\Gm10334, Mmus\Try4, Mmus\Gm5771" "Hsap\PRSS1, Hsap\PRSS3" FBgn0038603 PKD Protein Kinase D http://flybase.org/reports/FBgn0038603 protein_coding_gene "protein kinase C activity ; GO:0004697 | inferred from electronic annotation with InterPro:IPR015727 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR015727, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement" "protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR008271, InterPro:IPR015727 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement protein kinase D signaling ; GO:0089700 | inferred from biological aspect of ancestor with PANTHER:PTN000540182" cytoplasm ; GO:0005737 | inferred from direct assay "PKD, 150131_at, PKCm, CG7125, dPKD" "IPR000719:Protein kinase domain, IPR001849:Pleckstrin homology domain, IPR002219:Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR011993:PH domain-like, IPR015727:Protein kinase C mu-related, IPR017441:Protein kinase, ATP binding site, IPR020454:Diacylglycerol/phorbol-ester binding" CG7125 27-Aug-18 DroID_v2018_08 "Drer\zgc:175248, Drer\LOC797974, Drer\prkd3, Drer\prkd1" Scer\CLA4 "Cele\F48G7.9, Cele\F48G7.10, Cele\R12G8.1, Cele\dkf-1, Cele\dkf-2" "Xtro\prkd1, Xtro\prkd3" "Mmus\Prkd3, Mmus\Prkd2, Mmus\Prkd1" "Hsap\PRKD1, Hsap\PRKD3, Hsap\PRKD2" viable FBgn0005512 l(2)25Bg lethal (2) 25Bg http://flybase.org/reports/FBgn0005512 - gene - - - "jf16, l(2)jf16, l(2)25Bg" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0024884 l(2)03055 lethal (2) 03055 http://flybase.org/reports/FBgn0024884 - gene - - - "3055, l(2)03055" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0015485 l(2)46Ci lethal (2) 46Ci http://flybase.org/reports/FBgn0015485 FBgn0019715 gene - - - "M, 17.5, l(2)46CFm, l(2)46Ci" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0033815 CG4676 - http://flybase.org/reports/FBgn0033815 protein_coding_gene protein-cysteine S-palmitoyltransferase activity ; GO:0019706 | inferred from sequence or structural similarity with SGD:S000004236 protein palmitoylation ; GO:0018345 | inferred from sequence or structural similarity with SGD:S000004236 endoplasmic reticulum ; GO:0005783 | inferred from direct assay CG4676 "IPR001594:Palmitoyltransferase, DHHC domain" CG4676 27-Aug-18 DroID_v2018_08 "Drer\zdhhc1, Drer\zgc:77880, Drer\zdhhc21, Drer\zdhhc8b, Drer\zdhhc12b, Drer\zdhhc14, Drer\zdhhc9, Drer\zdhhc23a, Drer\zdhhc18a, Drer\zdhhc24, Drer\zdhhc3b, Drer\zdhhc7, Drer\zdhhc20b, Drer\LOC100334198, Drer\zdhhc5b, Drer\zdhhc12a, Drer\zdhhc22, Drer\zdhhc3a, Drer\zdhhc5a, Drer\zdhhc23b, Drer\zdhhc20a" "Scer\ERF2, Scer\PFA5" "Cele\dhhc-10, Cele\dhhc-12, Cele\dhhc-1, Cele\dhhc-9" "Xtro\zdhhc9, Xtro\zdhhc8, Xtro\zdhhc14, Xtro\zdhhc21, Xtro\zdhhc3, Xtro\zdhhc12, Xtro\dnz1, Xtro\zdhhc24, Xtro\zdhhc7, Xtro\zdhhc1" "Mmus\Zdhhc21, Mmus\Zdhhc11, Mmus\Zdhhc20, Mmus\Zdhhc12, Mmus\Zdhhc23, Mmus\Zdhhc3, Mmus\Zdhhc7, Mmus\Zdhhc22, Mmus\Zdhhc9, Mmus\Zdhhc8, Mmus\Zdhhc25, Mmus\Zdhhc24, Mmus\Zdhhc14, Mmus\Zdhhc19, Mmus\Zdhhc18, Mmus\Zdhhc5, Mmus\Zdhhc1" "Hsap\ZDHHC8, Hsap\ZDHHC19, Hsap\ZDHHC1, Hsap\ZDHHC11, Hsap\ZDHHC23, Hsap\ZDHHC7, Hsap\ZDHHC20, Hsap\ZDHHC14, Hsap\ZDHHC5, Hsap\ZDHHC9, Hsap\ZDHHC12, Hsap\ZDHHC24, Hsap\ZDHHC18, Hsap\ZDHHC3, Hsap\ZDHHC21, Hsap\ZDHHC22" viable FBgn0027546 CG4766 - http://flybase.org/reports/FBgn0027546 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "gh11415, BcDNA:GH11415, CG4766" "IPR024810:Mab-21 domain, IPR020950:Protein male abnormal 21-like 1/2" CG4766 27-Aug-18 DroID_v2018_08 "Drer\mab21l1, Drer\mb21d2, Drer\mab21l3, Drer\itprip, Drer\si:dkey-11f12.2, Drer\mab21l2, Drer\LOC556707, Drer\itpripl2" - Cele\mab-21 "Xtro\mb21d2, Xtro\mab21l1, Xtro\mab21l2" "Mmus\Itpripl1, Mmus\Mab21l3, Mmus\Itprip, Mmus\Mab21l2, Mmus\Itpripl2, Mmus\Tmem102, Mmus\Mb21d2, Mmus\Mb21d1, Mmus\2310007B03Rik, Mmus\Mab21l1" "Hsap\MAB21L3, Hsap\TMEM102, Hsap\ITPRIPL2, Hsap\MAB21L1, Hsap\MAB21L2, Hsap\ITPRIPL1, Hsap\ITPRIP, Hsap\MB21D1, Hsap\MB21D2, Hsap\C2orf54" viable FBgn0014271 l(2)k09619 lethal (2) k09619 http://flybase.org/reports/FBgn0014271 - gene - - - l(2)k09619 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" imaginal disc FBgn0260057 2L3937 - http://flybase.org/reports/FBgn0260057 gene - - - 2L3937 - - 27-Aug-18 DroID_v2018_08 - - - - - - "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0004852 Ac76E Adenylyl cyclase 76E http://flybase.org/reports/FBgn0004852 - protein_coding_gene guanylate cyclase activity ; GO:0004383 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 adenylate cyclase activity ; GO:0004016 | non-traceable author statement adenylate cyclase activity ; GO:0004016 | inferred from direct assay "intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR001054, InterPro:IPR018297 response to starvation ; GO:0042594 | inferred from direct assay instar larval or pupal development ; GO:0002165 | inferred from mutant phenotype signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 cAMP biosynthetic process ; GO:0006171 | inferred from direct assay negative regulation of multicellular organism growth ; GO:0040015 | inferred from mutant phenotype cGMP biosynthetic process ; GO:0006182 | inferred from biological aspect of ancestor with PANTHER:PTN000229249" "plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 guanylate cyclase complex, soluble ; GO:0008074 | inferred from biological aspect of ancestor with PANTHER:PTN000229249" "CG7978, AC 76E, DAC76E, DAC2, Ac76E, ac76e, AC76E" "IPR001054:Adenylyl cyclase class-3/4/guanylyl cyclase, IPR018297:Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR029787:Nucleotide cyclase, IPR032628:Adenylate cyclase, N-terminal" CG7978 27-Aug-18 DroID_v2018_08 "Drer\adcy2b, Drer\adcy1a, Drer\adcy7, Drer\adcy2a, Drer\adcy1b, Drer\adcy6b, Drer\adcy3a, Drer\adcy8, Drer\adcy6a, Drer\adcy5, Drer\si:dkey-206f10.1, Drer\si:ch211-132f19.7" - "Cele\acy-2, Cele\acy-4" "Xtro\dnajc27, Xtro\adcy1, Xtro\adcy6, Xtro\adcy4, Xtro\adcy7" "Mmus\Adcy5, Mmus\Adcy2, Mmus\Adcy7, Mmus\Adcy6, Mmus\Adcy3, Mmus\Adcy4, Mmus\Adcy8, Mmus\Adcy1" "Hsap\ADCY1, Hsap\ADCY8, Hsap\ADCY3, Hsap\ADCY7, Hsap\ADCY5, Hsap\ADCY6, Hsap\ADCY2, Hsap\ADCY4" "developmental rate defective,body size defective,starvation stress response defective,female limited" FBgn0010072 Mab66B2 Monoclonal antibody 66B2 http://flybase.org/reports/FBgn0010072 - gene - - - Mab66B2 - - 27-Aug-18 DroID_v2018_08 - - - - - - " larval stage , embryonic stage | 12-15 hr , pupal stage , embryonic stage " " imaginal disc

, embryonic/larval hindgut

, optic lobe

, epidermis

, neuropil

, central nervous system

, embryonic/larval foregut

, embryonic/larval trachea

, Keilin's organ

" FBgn0039876 CG2126 - http://flybase.org/reports/FBgn0039876 protein_coding_gene ubiquitin protein ligase binding ; GO:0031625 | inferred from sequence or structural similarity with HGNC:20184 ER-associated ubiquitin-dependent protein catabolic process ; GO:0030433 | inferred from sequence or structural similarity with HGNC:20184 cellular_component ; GO:0005575 | no biological data available "anon-WO0118547.412, CG2126" IPR008485:Protein of unknown function DUF766 CG2126 27-Aug-18 DroID_v2018_08 Drer\jkamp - Cele\jamp-1 Xtro\jkamp "Mmus\4931417E11Rik, Mmus\Jkamp" Hsap\JKAMP viable DRSC15418 E 0.863364304 0.056081719 -0.335910605 -2.634622219 1.088719498 -1.103259431 FBgn0022089 l(2)k07315 lethal (2) k07315 http://flybase.org/reports/FBgn0022089 - gene - - - l(2)k07315 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0005087 fs(2)OW811 female sterile (2) OW811 http://flybase.org/reports/FBgn0005087 - gene - - - fs(2)OW811 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0061483 rover\gag rover element gag http://flybase.org/reports/FBgn0061483 transposable_element_gene - - - rover\gag - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000933 fs(2)A3 female sterile (2) A3 http://flybase.org/reports/FBgn0000933 - gene - - - fs(2)A3 - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive" female reproductive system FBgn0032562 CG18483 - http://flybase.org/reports/FBgn0032562 protein_coding_gene - - - "Ms(2)35Ci, BG:DS07851.10, CG18483" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0013484 l(1)4Fb lethal (1) 4Fb http://flybase.org/reports/FBgn0013484 - gene - - - l(1)4Fb - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0065372 l(2)SH1694 lethal (2) SH1694 http://flybase.org/reports/FBgn0065372 gene - - - "l(2)SH1694, l(2)SH2 1694" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0004758 l(3)89Bk lethal (3) 89Bk http://flybase.org/reports/FBgn0004758 - gene - - - l(3)89Bk - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0014148 dkn deathknell http://flybase.org/reports/FBgn0014148 - gene - - - dkn - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0041091 ubi-d4 ubi-d4 http://flybase.org/reports/FBgn0041091 gene - - - ubi-d4 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001508 l(1)10Fb lethal (1) 10Fb http://flybase.org/reports/FBgn0001508 - gene - - - l(1)10Fb - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" "ovariole,germline clone,egg" FBgn0013516 l(1)XWJ lethal (1) XWJ http://flybase.org/reports/FBgn0013516 - gene - - - "XWJ, l(1)XWJ" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001916 l(2)25Bc lethal (2) 25Bc http://flybase.org/reports/FBgn0001916 - gene - - - "jf12, l(2)jf12, l(2)25Bc" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0000753 fs(1)A426 female sterile (1) A426 http://flybase.org/reports/FBgn0000753 - gene - - - fs(1)A426 - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive,heat sensitive,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage" embryo FBgn0035388 CG2162 - http://flybase.org/reports/FBgn0035388 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001374 - exon-exon junction complex ; GO:0035145 | inferred from biological aspect of ancestor with PANTHER:PTN000495129 "anon-EST:Posey170, CG2162" "IPR001374:R3H domain, IPR000504:RNA recognition motif domain" CG2162 27-Aug-18 DroID_v2018_08 "Drer\r3hcc1, Drer\r3hcc1l" - Cele\F09C8.2 - "Mmus\R3hcc1, Mmus\R3hcc1l" "Hsap\R3HCC1, Hsap\R3HCC1L" "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" DRSC08557 I -0.995653385 -1.829900572 -0.127522695 -0.161080206 0.227530834 0.257245196 FBgn0003384 shakA shaking A http://flybase.org/reports/FBgn0003384 - gene - - - shakA - - 27-Aug-18 DroID_v2018_08 - - - - - - "hyperactive,courtship behavior defective,heat sensitive,jumping defective,flight defective,uncoordinated,hypoactive" FBgn0053339 CG33339 - http://flybase.org/reports/FBgn0053339 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG13612, CG33339" IPR006631:Protein of unknown function DM4/12 CG33339 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0086883 Pab Pale body http://flybase.org/reports/FBgn0086883 gene - - - Pab - - 27-Aug-18 DroID_v2018_08 - - - - - - "body color defective,dominant,lethal,recessive" "adult cuticle,antenna,tergite" FBgn0036747 CG6052 - http://flybase.org/reports/FBgn0036747 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR017871 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from sequence or structural similarity with UniProtKB:O94911 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from biological aspect of ancestor with PANTHER:PTN000442469" transport ; GO:0006810 | inferred from sequence or structural similarity with UniProtKB:O94911 lipid transport ; GO:0006869 | inferred from biological aspect of ancestor with PANTHER:PTN000442469 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000442469 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with UniProtKB:Q9BZC7 CG6052 "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR017871:ABC transporter, conserved site, IPR026082:ABC transporter A, ABCA" CG6052 27-Aug-18 DroID_v2018_08 "Drer\abca1b, Drer\abca5, Drer\abca2, Drer\abch1, Drer\abca12, Drer\abca1a, Drer\abca3b" "Scer\SNQ2, Scer\PDR15, Scer\PDR10, Scer\CAF16, Scer\PDR5, Scer\PDR18, Scer\YOL075C, Scer\AUS1, Scer\PDR12, Scer\PDR11" "Cele\abt-4, Cele\ced-7, Cele\abt-2, Cele\abt-5" "Xtro\abca9, Xtro\abca2, Xtro\abca10, Xtro\abca3, Xtro\abca1, Xtro\abca4, Xtro\abca8" "Mmus\Abca3, Mmus\Abca13, Mmus\Abca9, Mmus\Abca8b, Mmus\Abca12, Mmus\Abca17, Mmus\Abca2, Mmus\Abca5, Mmus\Abca7, Mmus\Abca16, Mmus\Abca8a, Mmus\Abca6, Mmus\Abca14, Mmus\Abca1, Mmus\Abca4, Mmus\Abca15" "Hsap\ABCA12, Hsap\ABCA7, Hsap\ABCA2, Hsap\ABCA6, Hsap\ABCA8, Hsap\ABCA1, Hsap\ABCA13, Hsap\ABCA5, Hsap\ABCA10, Hsap\ABCA4, Hsap\ABCA3, Hsap\ABCA9" viable FBgn0013322 Pcp82 Pupal-cuticle-protein-82kD http://flybase.org/reports/FBgn0013322 - gene - - - Pcp82 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037976 Tk Tachykinin http://flybase.org/reports/FBgn0037976 protein_coding_gene tachykinin receptor binding ; GO:0071861 | inferred from physical interaction with TkR86C neuropeptide hormone activity ; GO:0005184 | inferred from sequence or structural similarity receptor binding ; GO:0005102 | non-traceable author statement tachykinin receptor binding ; GO:0071861 | inferred from physical interaction with TkR99D adult walking behavior ; GO:0007628 | inferred from mutant phenotype sensory perception of smell ; GO:0007608 | inferred from mutant phenotype tachykinin receptor signaling pathway ; GO:0007217 | inferred from direct assay positive regulation of sensory perception of pain ; GO:1904058 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype neuropeptide signaling pathway ; GO:0007218 | inferred from sequence or structural similarity response to pheromone ; GO:0019236 | inferred from mutant phenotype lipid metabolic process ; GO:0006629 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred by curator from GO:0071861 extracellular space ; GO:0005615 | inferred from direct assay "DTK1, Drm-TK-3, CG14734, Drm-TK-6, Drm-TK-5, Drm-TK-4, Drm-TK-2, Drm-TK-1, Drm-TK, Dtk, Tk, dtk, DTK, Tyk, TK-1, TK, DTK-6, DTK-3, DTK-2, DTK-5, DTK-1, DTK-4, TAP-5, DmTK6, dTK, Tachykinin 1, Tachykinin 2, Tachykinin 4, Tachykinin 5" - CG14734 27-Aug-18 DroID_v2018_08 Drer\tac1 - - Xtro\tac1 Mmus\Tac1 Hsap\TAC1 "viable,fertile,behavior defective,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,smell perception defective,locomotor behavior defective,female" FBgn0000421 displaced displaced http://flybase.org/reports/FBgn0000421 - gene - - - "dd, displaced" - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,female sterile" "antenna,adult head,eye" FBgn0267710 lncRNA:CR46043 - http://flybase.org/reports/FBgn0267710 non_protein_coding_gene - - - CR46043 - CR46043 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031058 CG14227 - http://flybase.org/reports/FBgn0031058 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | NOT non-traceable author statement" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - "SPH158, CG14227" "IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan, IPR001314:Peptidase S1A, chymotrypsin family, IPR018114:Serine proteases, trypsin family, histidine active site" CG14227 27-Aug-18 DroID_v2018_08 - - Cele\try-3 - "Mmus\Tpsab1, Mmus\Prss28, Mmus\Prss30, Mmus\Klk8, Mmus\Prss29, Mmus\Klk14, Mmus\Tpsb2, Mmus\Klk7, Mmus\Prss33, Mmus\Klk5, Mmus\Prss48, Mmus\Klk4, Mmus\Prss32, Mmus\Prss46, Mmus\Klk10, Mmus\F12, Mmus\Tpsg1, Mmus\Prss34, Mmus\Klk12, Mmus\Prss21, Mmus\Hgfac" "Hsap\F12, Hsap\TPSAB1, Hsap\TPSD1, Hsap\HGFAC, Hsap\PRSS48, Hsap\KLK8, Hsap\KLK4, Hsap\KLK5, Hsap\TPSG1, Hsap\KLK10, Hsap\KLK14, Hsap\PRSS33, Hsap\KLK12, Hsap\TPSB2, Hsap\PRSS21, Hsap\KLK7" FBgn0031936 CG13794 - http://flybase.org/reports/FBgn0031936 protein_coding_gene neurotransmitter:sodium symporter activity ; GO:0005328 | inferred from electronic annotation with InterPro:IPR000175 transporter activity ; GO:0005215 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 neurotransmitter:sodium symporter activity ; GO:0005328 | inferred from sequence model neurotransmitter transporter activity ; GO:0005326 | inferred from sequence or structural similarity with DAT neurotransmitter transport ; GO:0006836 | inferred from sequence model transport ; GO:0006810 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 neurotransmitter transport ; GO:0006836 | inferred from sequence or structural similarity with DAT integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 integral component of membrane ; GO:0016021 | inferred from sequence model CG13794 IPR000175:Sodium:neurotransmitter symporter CG13794 27-Aug-18 DroID_v2018_08 Drer\zgc:158225 - "Cele\snf-6, Cele\snf-10" - "Mmus\Slc6a3, Mmus\Slc6a7" "Hsap\SLC6A14, Hsap\SLC6A7" viable FBgn0047330 CG32235 - http://flybase.org/reports/FBgn0047330 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT25643, CG32235" - CG32235 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,some die during pupal stage,viable" FBgn0011083 l(1)Q41 lethal (1) Q41 http://flybase.org/reports/FBgn0011083 FBgn0010210 gene - - - l(1)Q41 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0039025 Usp12-46 Ubiquitin-specific protease 12/46 http://flybase.org/reports/FBgn0039025 protein_coding_gene thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from sequence or structural similarity with HGNC:20485 ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from electronic annotation with InterPro:IPR018200 protein deubiquitination ; GO:0016579 | inferred from sequence or structural similarity with HGNC:20485 negative regulation of Notch signaling pathway ; GO:0045746 | inferred from mutant phenotype inferred from genetic interaction with N inferred from genetic interaction with spdo cellular_component ; GO:0005575 | no biological data available "CG7023, Usp12-46, Q9VCT9, Usp12, Usp12/46" "IPR001394:Peptidase C19, ubiquitin carboxyl-terminal hydrolase, IPR018200:Ubiquitin specific protease, conserved site, IPR028889:Ubiquitin specific protease domain" CG7023 27-Aug-18 DroID_v2018_08 "Drer\usp1, Drer\usp12a, Drer\usp12b, Drer\usp38, Drer\usp46" "Scer\UBP13, Scer\UBP9" Cele\usp-46 "Xtro\usp1, Xtro\usp46, Xtro\usp35, Xtro\hapln3" "Mmus\Usp38, Mmus\Usp35, Mmus\Usp1, Mmus\Usp12, Mmus\Usp46" "Hsap\USP12, Hsap\USP46, Hsap\USP1, Hsap\USP38, Hsap\USP35" viable "mesothoracic tergum,socket,eo sensory structure" FBgn0001629 l(1)dn6 lethal (1) discs normal 6 http://flybase.org/reports/FBgn0001629 - gene - - - "l(1)d.norm.-6, l(1)dn6" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0033871 CG13339 - http://flybase.org/reports/FBgn0033871 protein_coding_gene - - - "BcDNA:RE69336, CG13339" - CG13339 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0046886 Gr98c Gustatory receptor 98c http://flybase.org/reports/FBgn0046886 protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 integral component of membrane ; GO:0016021 | non-traceable author statement axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 "Gr98A1, CG12884, Gr98B3, Gr98A2, 98B.3, GR98B.3, CG31060, Gr98c, GR98c" IPR013604:7TM chemoreceptor CG31060 27-Aug-18 DroID_v2018_08 - - "Cele\gur-3, Cele\lite-1" - - - viable FBgn0029720 CG3009 - http://flybase.org/reports/FBgn0029720 protein_coding_gene phospholipase A2 activity ; GO:0004623 | inferred from electronic annotation with InterPro:IPR016090 arachidonic acid secretion ; GO:0050482 | inferred from electronic annotation with InterPro:IPR016090 phospholipid metabolic process ; GO:0006644 | inferred from electronic annotation with InterPro:IPR016090 - CG3009 "IPR016090:Phospholipase A2 domain, IPR033113:Phospholipase A2, histidine active site" CG3009 27-Aug-18 DroID_v2018_08 "Drer\proca1, Drer\LOC101885160, Drer\zgc:123275" - - Xtro\proca1 "Mmus\Proca1, Mmus\Pla2g3" "Hsap\PLA2G3, Hsap\PROCA1" "viable,fertile" FBgn0267346 T:FK506-bp2 - http://flybase.org/reports/FBgn0267346 engineered_tag - - - T:FK506-bp2 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0261812 CG42754 - http://flybase.org/reports/FBgn0261812 protein_coding_gene - - - CG42754 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0045486 Gr36b Gustatory receptor 36b http://flybase.org/reports/FBgn0045486 protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 taste receptor activity ; GO:0008527 | non-traceable author statement sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of taste ; GO:0050909 | non-traceable author statement integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 integral component of membrane ; GO:0016021 | non-traceable author statement neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 "Gr36B.2, CG15137, Gr36B2, CG31744, Gr36b, GR36b" IPR013604:7TM chemoreceptor CG31744 27-Aug-18 DroID_v2018_08 - - "Cele\lite-1, Cele\gur-3" - - - viable FBgn0001187 Hex-C Hexokinase C http://flybase.org/reports/FBgn0001187 FBgn0034003 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001312, InterPro:IPR022672, InterPro:IPR022673 glucose binding ; GO:0005536 | inferred from electronic annotation with InterPro:IPR001312 mannokinase activity ; GO:0019158 | inferred from biological aspect of ancestor with PANTHER:PTN000455350 fructokinase activity ; GO:0008865 | inferred from biological aspect of ancestor with PANTHER:PTN000455350 hexokinase activity ; GO:0004396 | inferred from direct assay glucokinase activity ; GO:0004340 | inferred from biological aspect of ancestor with PANTHER:PTN000455350" carbohydrate phosphorylation ; GO:0046835 | inferred from electronic annotation with InterPro:IPR001312 glycolytic process ; GO:0006096 | inferred from biological aspect of ancestor with PANTHER:PTN000455350 lateral inhibition ; GO:0046331 | inferred from mutant phenotype cellular glucose homeostasis ; GO:0001678 | inferred from biological aspect of ancestor with PANTHER:PTN000455350 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000455350 "Hex-C, CT22069, HK, DM2, CG8094, HEX, Hk, HEX-C, Hex-c, Hex, HEX-3, Hex-3, Fk, HK-C, HexC" "IPR001312:Hexokinase, IPR022672:Hexokinase, N-terminal, IPR022673:Hexokinase, C-terminal" CG8094 27-Aug-18 DroID_v2018_08 "Drer\hkdc1, Drer\gck, Drer\hk2, Drer\hk1" "Scer\EMI2, Scer\HXK1, Scer\HXK2, Scer\GLK1, Scer\YLR446W" "Cele\hxk-2, Cele\hxk-3, Cele\hxk-1" "Xtro\hk2, Xtro\gck, Xtro\hk1" "Mmus\Gck, Mmus\Hk3, Mmus\Hkdc1, Mmus\Hk2, Mmus\Hk1" "Hsap\HKDC1, Hsap\HK1, Hsap\HK2, Hsap\GCK, Hsap\HK3" "electrophoretic variant,viable,visible" "chaeta,trichogen cell,supernumerary,tormogen cell" FBgn0039625 beta4GalNAcTB beta4GalNAcTB http://flybase.org/reports/FBgn0039625 protein_coding_gene "beta-1,4-N-acetylgalactosaminyltransferase activity ; GO:0033207 | inferred from direct assay N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity ; GO:0033842 | inferred from direct assay acetylgalactosaminyltransferase activity ; GO:0008376 | inferred from direct assay" carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR003859 glycolipid biosynthetic process ; GO:0009247 | inferred from direct assay N-acetylglucosamine metabolic process ; GO:0006044 | inferred from direct assay glycosphingolipid biosynthetic process ; GO:0006688 | inferred from mutant phenotype Golgi apparatus ; GO:0005794 | inferred from direct assay "CG14517, dbeta4GalTB, beta4GalTB, beta4GalNAcTB" "IPR003859:Beta-1,4-galactosyltransferase, IPR029044:Nucleotide-diphospho-sugar transferases, IPR027995:Galactosyltransferase, N-terminal, IPR027791:Galactosyltransferase, C-terminal" CG14517 27-Aug-18 DroID_v2018_08 "Drer\b4galt1l, Drer\b4galt5, Drer\b4galt3, Drer\si:dkey-199f5.8, Drer\b4galt2, Drer\b4galt4, Drer\b4galt1, Drer\b4galt6" Scer\TMA20 Cele\bre-4 "Xtro\b4galt1.2, Xtro\LOC100485024, Xtro\b4galt1.1, Xtro\b4galt6, Xtro\b4galt3, Xtro\b4galt5, Xtro\b4galt2, Xtro\b4galt4" "Mmus\B4galt1, Mmus\B4galt4, Mmus\B4galt3, Mmus\B4galt2, Mmus\B4galt5, Mmus\B4galt6" "Hsap\B4GALT4, Hsap\B4GALT2, Hsap\B4GALT5, Hsap\B4GALT3, Hsap\B4GALT6, Hsap\B4GALT1" "viable,fertile" FBgn0070011 BG01296 BG01296 http://flybase.org/reports/FBgn0070011 gene - - - BG01296 - - 27-Aug-18 DroID_v2018_08 - - - - - - stress response defective FBgn0037688 CG9356 - http://flybase.org/reports/FBgn0037688 protein_coding_gene - Golgi to plasma membrane protein transport ; GO:0043001 | inferred from electronic annotation with InterPro:IPR027095 Golgi organization ; GO:0007030 | inferred from electronic annotation with InterPro:IPR027095 - "CG9356, Golgin-45" IPR027095:Golgin-45 CG9356 27-Aug-18 DroID_v2018_08 Drer\blzf1 - Cele\R12B2.2 Xtro\blzf1 Mmus\Blzf1 Hsap\BLZF1 FBgn0036937 Ir76b Ionotropic receptor 76b http://flybase.org/reports/FBgn0036937 protein_coding_gene ionotropic glutamate receptor activity ; GO:0004970 | inferred from electronic annotation with InterPro:IPR001320 sodium channel activity ; GO:0005272 | inferred from direct assay salty taste receptor activity ; GO:0033039 | inferred from mutant phenotype olfactory receptor activity ; GO:0004984 | contributes_to inferred from direct assay ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model transmission of nerve impulse ; GO:0019226 | inferred from mutant phenotype cellular response to salt ; GO:1902075 | inferred from mutant phenotype detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from direct assay detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a salt aversion ; GO:0035199 | NOT inferred from mutant phenotype membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001320 sensory dendrite ; GO:0071683 | inferred from direct assay receptor complex ; GO:0043235 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model "Ir76b, CT22733, IR76b, CG7385, DmelIR76b, ir76b" IPR001320:Ionotropic glutamate receptor CG7385 27-Aug-18 DroID_v2018_08 - - - - - - "neurophysiology defective,chemosensitive behavior defective,viable" "L-type sensilla L6,L-type sensilla L4,L-type sensilla L2" FBgn0265422 lncRNA:CR44334 - http://flybase.org/reports/FBgn0265422 non_protein_coding_gene - - - CR44334 - CR44334 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0046117 E(To)9 E(To)9 http://flybase.org/reports/FBgn0046117 gene - - - E(To)9 - - 27-Aug-18 DroID_v2018_08 - - - - - - "sterile,recessive,viable,visible" "dorsal appendage,eye,wing margin" FBgn0265640 lncRNA:CR44447 - http://flybase.org/reports/FBgn0265640 non_protein_coding_gene - - - CR44447 - CR44447 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263031 CG43326 - http://flybase.org/reports/FBgn0263031 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG13514, CG30217, CG43326" IPR006629:LPS-induced tumour necrosis factor alpha factor CG43326 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040787 CG12518 - http://flybase.org/reports/FBgn0040787 protein_coding_gene - - - CG12518 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0022088 l(2)k07332 lethal (2) k07332 http://flybase.org/reports/FBgn0022088 - gene - - - l(2)k07332 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0002911 mwg micro-wing http://flybase.org/reports/FBgn0002911 - gene - - - mwg - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,fertile,viable" "wing,haltere" FBgn0084004 CG41437 - http://flybase.org/reports/FBgn0084004 protein_coding_gene - - - CG41437 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0062564 P10 P10 http://flybase.org/reports/FBgn0062564 gene - - - P10 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0022110 l(2)k06918 lethal (2) k06918 http://flybase.org/reports/FBgn0022110 - gene - - - l(2)k06918 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0039779 PH4alphaSG2 prolyl-4-hydroxylase-alpha SG2 http://flybase.org/reports/FBgn0039779 protein_coding_gene "procollagen-proline 4-dioxygenase activity ; GO:0004656 | inferred from electronic annotation with InterPro:IPR013547 L-ascorbic acid binding ; GO:0031418 | inferred from electronic annotation with InterPro:IPR006620 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen ; GO:0016702 | inferred from electronic annotation with InterPro:IPR013547 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR006620" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005123, InterPro:IPR006620, InterPro:IPR013547 salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype" endoplasmic reticulum ; GO:0005783 | inferred from direct assay "CG1546, PH4alphaSG2, SG2" "IPR005123:Oxoglutarate/iron-dependent dioxygenase, IPR006620:Prolyl 4-hydroxylase, alpha subunit, IPR011990:Tetratricopeptide-like helical domain, IPR013547:Prolyl 4-hydroxylase alpha-subunit, N-terminal" CG1546 27-Aug-18 DroID_v2018_08 "Drer\p4ha2, Drer\p4ha1b, Drer\p4ha1a, Drer\p4ha3, Drer\zgc:158254, Drer\p4htm, Drer\zgc:152670" - "Cele\phy-2, Cele\phy-4, Cele\C14E2.4, Cele\Y43F8B.19, Cele\dpy-18, Cele\phy-3" "Xtro\p4ha1, Xtro\p4ha2, Xtro\p4ha3" "Mmus\P4ha1, Mmus\P4ha3, Mmus\P4htm, Mmus\P4ha2" "Hsap\P4HA3, Hsap\P4HA1, Hsap\P4HA2, Hsap\P4HTM" viable FBgn0036489 CG7011 - http://flybase.org/reports/FBgn0036489 protein_coding_gene molecular_function ; GO:0003674 | no biological data available ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from sequence or structural similarity with SGD:S000000040 - CG7011 "IPR012936:Endoplasmic reticulum vesicle transporter, C-terminal" CG7011 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-225b10.3, Drer\ergic1, Drer\ergic3, Drer\ergic2" "Scer\ERV41, Scer\ERV46" Cele\erv-46 "Xtro\ergic3, Xtro\ergic1, Xtro\ergic2" "Mmus\Ergic3, Mmus\Ergic2, Mmus\Ergic1" "Hsap\ERGIC1, Hsap\ERGIC3, Hsap\ERGIC2" viable FBgn0260630 f06222 - http://flybase.org/reports/FBgn0260630 gene - - - f06222 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0045860 crle crippled leg http://flybase.org/reports/FBgn0045860 gene - - - crle - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004078 Ars-region13 Autonomous replicating sequence region 13 http://flybase.org/reports/FBgn0004078 - region - - - "Ars-region13, Ars13" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0286198 LKRSDH Lysine ketoglutarate reductase/saccharopine dehydrogenase http://flybase.org/reports/FBgn0025687 "FBgn0031949, FBgn0045950" protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR005097 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005097 regulation of histone methylation ; GO:0031060 | inferred from direct assay histone arginine methylation ; GO:0034969 | inferred from direct assay - "CG7144, BEST:CK02318, CK02318, anon-WO0149856.1, LKRSDH, LKR, dLKR, SDH" "IPR005097:Saccharopine dehydrogenase, NADP binding domain, IPR007698:Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain, IPR007886:Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal, IPR016040:NAD(P)-binding domain, IPR032095:Saccharopine dehydrogenase, C-terminal" CG7144 27-Aug-18 DroID_v2018_08 Drer\aass "Scer\LYS9, Scer\LYS1" Cele\R02D3.1 Xtro\aass Mmus\Aass Hsap\AASS pupal stage salivary gland

"viable,fertile" wing FBgn0262385 mir-307a mir-307a stem loop http://flybase.org/reports/FBgn0262385 miRNA_gene - - - "dme-mir-307a, miR-307, mir-307a, mir-307, CR42913, CR33611, miR-307a, dme-miR-307a" - CR42913 27-Aug-18 DroID_v2018_08 - - - - - - "visible,lethal" wing FBgn0003247 rh roughish http://flybase.org/reports/FBgn0003247 - gene - compound eye development ; GO:0048749 | inferred from mutant phenotype - rh - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive" "eye disc,ommatidium,eye photoreceptor cell,eye" FBgn0267385 PyK Pyruvate kinase http://flybase.org/reports/FBgn0267385 protein_coding_gene "magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR001697, InterPro:IPR015793, InterPro:IPR015794 potassium ion binding ; GO:0030955 | inferred from electronic annotation with InterPro:IPR001697, InterPro:IPR015793, InterPro:IPR015794 pyruvate kinase activity ; GO:0004743 | inferred from mutant phenotype" somatic muscle development ; GO:0007525 | inferred from mutant phenotype glycolytic process ; GO:0006096 | inferred from sequence or structural similarity with SGD:S000000036 response to sucrose ; GO:0009744 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype pyruvate metabolic process ; GO:0006090 | inferred from sequence or structural similarity with SGD:S000000036 myoblast fusion ; GO:0007520 | inferred from mutant phenotype P granule ; GO:0043186 | inferred from physical interaction with tud inferred from physical interaction with vas cytosol ; GO:0005829 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay "Pyk, PK, PyK, l(3)r[Q178], CG7070, PYK, l(3)rQ178, Pk" "IPR018209:Pyruvate kinase, active site, IPR015813:Pyruvate/Phosphoenolpyruvate kinase-like domain, IPR001697:Pyruvate kinase, IPR011037:Pyruvate kinase-like, insert domain, IPR015793:Pyruvate kinase, barrel, IPR015795:Pyruvate kinase, C-terminal" CG7070 27-Aug-18 DroID_v2018_08 "Drer\pklr, Drer\pkma, Drer\pkmb" "Scer\CDC19, Scer\PYK2" "Cele\pyk-2, Cele\pyk-1" "Xtro\pklr, Xtro\pkm" "Mmus\Pklr, Mmus\Pkm" "Hsap\PKM, Hsap\PKLR" FBgn0000241 bw brown http://flybase.org/reports/FBgn0000241 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR017871 cholesterol transporter activity ; GO:0017127 | inferred from biological aspect of ancestor with PANTHER:PTN001059382 sterol-transporting ATPase activity ; GO:0034041 | inferred from biological aspect of ancestor with PANTHER:PTN001059382 synaptic vesicle amine transmembrane transporter activity ; GO:0005430 | inferred from mutant phenotype" ommochrome biosynthetic process ; GO:0006727 | inferred from mutant phenotype aminergic neurotransmitter loading into synaptic vesicle ; GO:0015842 | inferred from mutant phenotype sensory perception of sound ; GO:0007605 | inferred from mutant phenotype eye pigment precursor transport ; GO:0006856 | traceable author statement integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000443108 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000443108 "bw, CG17632, Pm, Su(w[coJ]), ptm, Su(w[co2])" "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR013525:ABC-2 type transporter, IPR005284:Pigment precursor permease, IPR017871:ABC transporter, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG17632 27-Aug-18 DroID_v2018_08 "Drer\abcg8, Drer\abcg2a, Drer\abcg4b, Drer\abcg4a, Drer\abcg1, Drer\abcg2b, Drer\abcg5" "Scer\ADP1, Scer\PDR18, Scer\YOL075C, Scer\PDR10, Scer\SNQ2, Scer\PDR15, Scer\PDR5" "Cele\wht-6, Cele\abch-1, Cele\wht-2, Cele\wht-3, Cele\wht-8" "Xtro\abcg5, Xtro\abcg8" "Mmus\Abcg8, Mmus\Abcg4, Mmus\Abcg2, Mmus\Abcg1, Mmus\Abcg3, Mmus\Abcg5" "Hsap\ABCG4, Hsap\ABCG8, Hsap\ABCG1, Hsap\ABCG5" "eye color defective,dominant,chemical resistant,male,auditory perception defective,visible,viable,recessive,wild-type,lethal,fertile,enhancer of variegation" "pigment cell,pigment granule,hemolymph,ocellus,wing,eye" FBgn0267244 lncRNA:CR45684 - http://flybase.org/reports/FBgn0267244 non_protein_coding_gene - - - CR45684 - CR45684 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0052102 CG32102 - http://flybase.org/reports/FBgn0052102 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE42781, CG32102" - CG32102 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0003236 reti reticent http://flybase.org/reports/FBgn0003236 - gene - - - "ret, reti" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,recessive,some die during embryonic stage" FBgn0001876 l(1)XN82b lethal (1) XN82b http://flybase.org/reports/FBgn0001876 - gene - - - l(1)XN82b - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0045850 l(4)102Fc lethal (4) 102Fc http://flybase.org/reports/FBgn0045850 gene - - - l(4)102Fc - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0031959 spz3 spatzle 3 http://flybase.org/reports/FBgn0031959 protein_coding_gene Toll binding ; GO:0005121 | inferred from sequence or structural similarity with spz Toll signaling pathway ; GO:0008063 | inferred from sequence or structural similarity with spz extracellular region ; GO:0005576 | inferred from sequence or structural similarity with spz "CG14533, CG7104, spz3, Spz3, CT21967, CT34263" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR029034:Cystine-knot cytokine, IPR032104:Spaetzle" CG7104 27-Aug-18 DroID_v2018_08 - Scer\MRPS17 - - - Hsap\AUH "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0011446 l(3)neo2 lethal (3) neo2 http://flybase.org/reports/FBgn0011446 - gene - - - l(3)neo2 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0062701 EP1095 EP1095 http://flybase.org/reports/FBgn0062701 gene - - - "EP(2)1095, EP1095" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262997 CR43305 - http://flybase.org/reports/FBgn0262997 non_protein_coding_gene - - - CR43305 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0011610 l(1)I33e14 lethal (1) I33e14 http://flybase.org/reports/FBgn0011610 FBgn0010206 gene - - - "l(1)33e14, l(1)I33e14" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0259597 B0633 - http://flybase.org/reports/FBgn0259597 gene - - - B0633 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible wing FBgn0262883 lncRNA:CR43238 - http://flybase.org/reports/FBgn0262883 non_protein_coding_gene - - - "CR43238, chr3R:26,572,448-26,572,516" - CR43238 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001120 gnu giant nuclei http://flybase.org/reports/FBgn0001120 FBgn0036453 protein_coding_gene molecular_function ; GO:0003674 | no biological data available regulation of cell cycle ; GO:0051726 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype negative regulation of DNA replication ; GO:0008156 | inferred from mutant phenotype egg activation ; GO:0007343 | inferred from mutant phenotype regulation of cell cycle ; GO:0051726 | traceable author statement mitotic nuclear division ; GO:0007067 | traceable author statement inferred from genetic interaction with CycB regulation of mitotic cell cycle ; GO:0007346 | traceable author statement - "CG5272, Gnu, gnu" "IPR001660:Sterile alpha motif domain, IPR013761:Sterile alpha motif/pointed domain" CG5272 27-Aug-18 DroID_v2018_08 - - - - - - " adult stage && O | stage S>=11 , embryonic stage | 0-1 hr " " oocyte

, organism

" "lethal,maternal effect,recessive,mitotic cell cycle defective,meiotic cell cycle defective,viable" "cleavage nucleus,maternal effect,female pronucleus | maternal effect,polar body nucleus,female,mitotic cell cycle | cleavage stage | maternal effect,cleavage stage embryo,nurse cell & nucleusmat.ë±Tub67C.THsimVP16,ovary,actin filament & nurse cellmat.ë±Tub67C.THsimVP16" FBgn0011671 musculin musculin http://flybase.org/reports/FBgn0011671 - gene - - - musculin - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259475 C464 - http://flybase.org/reports/FBgn0259475 gene - - - C464 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible wing hair FBgn0022974 snRNP120K snRNP120K http://flybase.org/reports/FBgn0022974 - gene - - - "120K, snRNP120K" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0050115 GEFmeso Guanine nucleotide exchange factor in mesoderm http://flybase.org/reports/FBgn0050115 protein_coding_gene Rho guanyl-nucleotide exchange factor activity ; GO:0005089 | inferred from physical interaction with Cdc42 Ral GTPase binding ; GO:0017160 | inferred from direct assay imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype regulation of Cdc42 protein signal transduction ; GO:0032489 | inferred from physical interaction with Cdc42 imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG5503, CG18430, CG30115, GEFmeso" "IPR000219:Dbl homology (DH) domain, IPR001849:Pleckstrin homology domain, IPR011993:PH domain-like" CG30115 27-Aug-18 DroID_v2018_08 "Drer\mcf2l2, Drer\plekhg2, Drer\vav3b, Drer\spata13, Drer\arhgef4, Drer\arhgef9b, Drer\arhgef9a, Drer\LOC101885278, Drer\pex13, Drer\prex1, Drer\vav2, Drer\plekhg3" "Scer\PEX13, Scer\CDC24" "Cele\prx-13, Cele\vav-1, Cele\uig-1, Cele\tiam-1, Cele\Y37A1B.17" "Xtro\plekhg3, Xtro\plekhg1" "Mmus\Plekhg1, Mmus\Plekhg3, Mmus\Prex1, Mmus\Arhgef4, Mmus\Arhgef9, Mmus\Vav3, Mmus\Vav2, Mmus\Plekhg2, Mmus\Vav1, Mmus\Pex13, Mmus\Spata13" "Hsap\VAV2, Hsap\SPATA13, Hsap\PREX1, Hsap\PEX13, Hsap\PLEKHG2, Hsap\PLEKHG3, Hsap\VAV1, Hsap\PLEKHG1, Hsap\ARHGEF9, Hsap\ARHGEF4, Hsap\VAV3" "lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die" "crossvein,mesoderm,supernumerary" FBgn0264460 asRNA:CR43868 - http://flybase.org/reports/FBgn0264460 non_protein_coding_gene - - - CR43868 - CR43868 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265544 CR44394 - http://flybase.org/reports/FBgn0265544 pseudogene_attribute - - - CR44394 - CR44394 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051215 tRNA:Ala-AGC-2-11 transfer RNA:Alanine-AGC 2-11 http://flybase.org/reports/FBgn0051215 tRNA_gene GCU codon-amino acid adaptor activity ; GO:0033453 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033453 cytosol ; GO:0005829 | inferred by curator from GO:0033453 "AE002708.trna21-AlaAGC, tRNA:A:AGC:AE002708-f, CR31215, tRNA[[Ala]], chr3R.trna27-AlaAGC, tRNA-Ala-AGC-2-11, tRNA:Ala-AGC-2-11, tRNA:CR31215, GCU" - CR31215 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0026194 pana pollyanna http://flybase.org/reports/FBgn0026194 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "fret, pana" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260091 2L2676 - http://flybase.org/reports/FBgn0260091 gene - - - 2L2676 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" "embryonic/larval dorsal trunk,somatic clone" FBgn0051148 Gba1a Glucocerebrosidase 1a http://flybase.org/reports/FBgn0051148 protein_coding_gene glucosylceramidase activity ; GO:0004348 | inferred from genetic interaction with Gba1b glucosylceramide catabolic process ; GO:0006680 | inferred from biological aspect of ancestor with PANTHER:PTN001667738 adult locomotory behavior ; GO:0008344 | inferred from genetic interaction with Gba1b memory ; GO:0007613 | inferred from genetic interaction with Gba1b neuron cellular homeostasis ; GO:0070050 | inferred from genetic interaction with Gba1b determination of adult lifespan ; GO:0008340 | inferred from genetic interaction with Gba1b cellular response to unfolded protein ; GO:0034620 | inferred from genetic interaction with Gba1b lysosome ; GO:0005764 | inferred from biological aspect of ancestor with PANTHER:PTN000869635 "CG10299, CT28913, anon-WO0140519.234, CG31148, dGBA1a, Gba1a" "IPR001139:Glycoside hydrolase family 30, IPR017853:Glycoside hydrolase superfamily, IPR033452:Glycosyl hydrolase family 30, beta sandwich domain, IPR033453:Glycosyl hydrolase family 30, TIM-barrel domain" CG31148 27-Aug-18 DroID_v2018_08 Drer\gba - "Cele\gba-3, Cele\gba-1, Cele\gba-2, Cele\gba-4" - Mmus\Gba Hsap\GBA "viable,visible" mesothoracic tergum FBgn0002116 l(2)cg lethal (2) with comb gap http://flybase.org/reports/FBgn0002116 - gene - - - l(2)cg - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0029167 Hml Hemolectin http://flybase.org/reports/FBgn0029167 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 protein homodimerization activity ; GO:0042803 | inferred from direct assay chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 hemostasis ; GO:0007599 | inferred from expression pattern melanization defense response ; GO:0035006 | NOT inferred from mutant phenotype hemolymph coagulation ; GO:0042381 | inferred from mutant phenotype wound healing ; GO:0042060 | inferred from mutant phenotype hemostasis ; GO:0007599 | inferred from mutant phenotype extracellular region ; GO:0005576 | inferred from direct assay "Hml, hml, CG7002, d-hml, CT21553" "IPR000421:Coagulation factor 5/8 C-terminal domain, IPR000742:EGF-like domain, IPR001007:VWFC domain, IPR001846:von Willebrand factor, type D domain, IPR002557:Chitin binding domain, IPR002919:Trypsin Inhibitor-like, cysteine rich domain, IPR006207:Cystine knot, C-terminal, IPR012111:Hemolectin/hemocytin, IPR013032:EGF-like, conserved site, IPR014853:Uncharacterised domain, cysteine-rich, IPR008979:Galactose-binding domain-like, IPR002172:Low-density lipoprotein (LDL) receptor class A repeat" CG7002 27-Aug-18 DroID_v2018_08 "Drer\LOC100147849, Drer\asic2, Drer\otogl, Drer\muc2.1, Drer\si:ch211-39f2.3, Drer\tecta, Drer\LOC100329651, Drer\fras1, Drer\muc5f, Drer\scospondin, Drer\LOC101887000, Drer\vwf, Drer\si:dkey-65b12.6, Drer\si:dkey-239b22.1, Drer\LOC799643, Drer\muc5.2, Drer\LOC100147904, Drer\muc5.1, Drer\otog, Drer\ch1073-291c23.1, Drer\si:dkey-266m15.6, Drer\wu:fb63a08" "Scer\HPF1, Scer\HKR1, Scer\FLO9, Scer\YIL169C, Scer\MSB2, Scer\FLO1, Scer\FIG2, Scer\PRM7, Scer\YMR317W, Scer\FLO5, Scer\FLO11" "Cele\dpy-6, Cele\C18H7.1, Cele\H43E16.1, Cele\ZC178.2, Cele\clec-223, Cele\F36H9.4, Cele\C53B7.2, Cele\T01D3.6, Cele\C25E10.10, Cele\C10G8.4, Cele\H02F09.3, Cele\F53C11.9, Cele\srap-1" "Xtro\muc6, Xtro\tecta.1, Xtro\zan, Xtro\LOC100485197, Xtro\LOC100497909, Xtro\vwf, Xtro\otogl, Xtro\fras1, Xtro\kcp, Xtro\LOC100492852" "Mmus\Kcp, Mmus\Fcgbp, Mmus\Muc5ac, Mmus\Vwce, Mmus\Otogl, Mmus\Otog, Mmus\Fras1, Mmus\Muc5b, Mmus\Tecta, Mmus\Muc2, Mmus\Muc6, Mmus\9530053A07Rik, Mmus\Muc4, Mmus\Zan, Mmus\Sspo, Mmus\Vwf, Mmus\Muc19" "Hsap\FRAS1, Hsap\MUC16, Hsap\MUC6, Hsap\OTOG, Hsap\FCGBP, Hsap\MUC4, Hsap\MUC2, Hsap\MUC19, Hsap\MUC5B, Hsap\MUC5AC, Hsap\VWF, Hsap\TECTA, Hsap\VWCE, Hsap\ZAN, Hsap\OTOGL, Hsap\SSPO, Hsap\MUC17" " embryonic stage | stage 17 , larval stage | first instar , larval stage " " embryonic hemocyte

, larval hemocyte

, organism

, crystal cell | subset

, plasmatocyte | subset

" "viable,fertile,immune response defective" FBgn0028385 cod capodimonte http://flybase.org/reports/FBgn0028385 gene - - - cod - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004068 fs(2)mel2 female sterile (2) maternal effect lethal 2 http://flybase.org/reports/FBgn0004068 - gene - - - "mel 2, fs(2)mel2" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,recessive,some die during embryonic stage" "cephalopharyngeal skeleton,abdominal 1 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,embryo,maternal effect" FBgn0267132 lncRNA:CR45572 - http://flybase.org/reports/FBgn0267132 non_protein_coding_gene - - - CR45572 - CR45572 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040050 CG17403 - http://flybase.org/reports/FBgn0040050 protein_coding_gene - - - CG17403 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065757 l(2)SH0486 lethal (2) SH0486 http://flybase.org/reports/FBgn0065757 gene - - - "l(2)SH0486, l(2)SH2 0486" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0275436 PheRS-m "Phenylalanyl-tRNA synthetase, mitochondrial" http://flybase.org/reports/FBgn0275436 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002319, InterPro:IPR004530, InterPro:IPR005121 phenylalanine-tRNA ligase activity ; GO:0004826 | inferred from biological aspect of ancestor with PANTHER:PTN000165932 phenylalanine-tRNA ligase activity ; GO:0004826 | traceable author statement tRNA binding ; GO:0000049 | inferred from sequence or structural similarity with UniProtKB:O95363 phenylalanine-tRNA ligase activity ; GO:0004826 | inferred from sequence or structural similarity with UniProtKB:O95363 phenylalanine-tRNA ligase activity ; GO:0004826 | inferred from sequence or structural similarity with UniProtKB:P08425" phenylalanyl-tRNA aminoacylation ; GO:0006432 | traceable author statement tRNA processing ; GO:0008033 | inferred from sequence or structural similarity with UniProtKB:O95363 phenylalanyl-tRNA aminoacylation ; GO:0006432 | inferred from biological aspect of ancestor with PANTHER:PTN000165932 phenylalanyl-tRNA aminoacylation ; GO:0006432 | inferred from sequence or structural similarity with UniProtKB:O95363 phenylalanyl-tRNA aminoacylation ; GO:0006432 | inferred from sequence or structural similarity with UniProtKB:P08425 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000165999 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:P08425 mitochondrion ; GO:0005739 | traceable author statement "mtPheRS, PheRS, FRS, Pts, CG13348, Aats-phe, PheRS-m, Aats-phe-m" "IPR002319:Phenylalanyl-tRNA synthetase, IPR004530:Phenylalanyl-tRNA synthetase, class IIc, mitochondrial, IPR005121:Ferrodoxin-fold anticodon-binding domain, IPR006195:Aminoacyl-tRNA synthetase, class II" CG13348 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-71l1.3, Drer\fars2" Scer\MSF1 Cele\fars-2 "Xtro\alg9, Xtro\fars2" "Mmus\Fdxacb1, Mmus\Fars2" "Hsap\FARS2, Hsap\FDXACB1" "viable,visible,decreased cell size,cell autonomous,somatic clone" "trichogen cell,lysosome & larval fat body | somatic clone | cell autonomous" FBgn0032285 CG17108 - http://flybase.org/reports/FBgn0032285 protein_coding_gene - - - "CT33647, gh23489, BEST:GH23489, CG17108" - CG17108 27-Aug-18 DroID_v2018_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0038201 PK1-R Pyrokinin 1 receptor http://flybase.org/reports/FBgn0038201 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity inferred from direct assay pyrokinin receptor activity ; GO:0036401 | inferred from physical interaction with Capa neuropeptide receptor activity ; GO:0008188 | inferred from sequence model G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model triglyceride homeostasis ; GO:0070328 | inferred from mutant phenotype negative regulation of peptide hormone secretion ; GO:0090278 | inferred from mutant phenotype neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from sequence model "anon-WO0170980.113, anon-WO0170980.112, CG9918, PK1-R, Pk1r, Pk1R, pkr1" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG9918 27-Aug-18 DroID_v2018_08 "Drer\ghsrb, Drer\ntsr1, Drer\nmur3, Drer\LOC101885431, Drer\LOC101885494, Drer\LOC101885849, Drer\nmur1a, Drer\mlnr, Drer\nmur1b, Drer\ghsra, Drer\gpr39, Drer\LOC103910036" - "Cele\nmur-4, Cele\npr-32, Cele\nmur-1, Cele\nmur-2, Cele\nmur-3" Xtro\nmur2 "Mmus\Nmur2, Mmus\Gpr39, Mmus\Ghsr, Mmus\Ntsr2, Mmus\Nmur1, Mmus\Ntsr1" "Hsap\GHSR, Hsap\NTSR2, Hsap\GPR148, Hsap\NTSR1, Hsap\GPR39, Hsap\MLNR, Hsap\NMUR1, Hsap\NMUR2" "viable,fertile" FBgn0086417 l(3)CHa lethal (3) CHa http://flybase.org/reports/FBgn0086417 gene - - - l(3)CHa - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0004067 fs(2)mel1 female sterile (2) maternal effect lethal 1 http://flybase.org/reports/FBgn0004067 - gene - - - "mel 1, fs(2)mel1" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,recessive,some die during embryonic stage" "egg,maternal effect,embryo" FBgn0259713 CG42367 - http://flybase.org/reports/FBgn0259713 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG31878, CG42367, CG4588" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG42367 27-Aug-18 DroID_v2018_08 Drer\mak Scer\IME2 Cele\fbxb-38 "Xtro\mak, Xtro\ick" "Mmus\Mak, Mmus\Ick, Mmus\Mok" "Hsap\MOK, Hsap\ICK, Hsap\MAK" "viable,fertile" FBgn0050020 CG30020 - http://flybase.org/reports/FBgn0050020 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 DNA binding ; GO:0003677 | inferred from direct assay - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 "CG18353, CG12941, p190, BEST:LD40262, CG30020" "IPR012934:Zinc finger, AD-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG30020 27-Aug-18 DroID_v2018_08 - Scer\RME1 - Xtro\sall1 "Mmus\Zfp580, Mmus\Zfp524" "Hsap\ZNF581, Hsap\ZNF524, Hsap\ZNF580" "viable,fertile" DRSC06730 K 1.032061316 0.017303785 0.417735398 -0.024358721 -1.79978409 -0.412861659 FBgn0085591 CG41274 - http://flybase.org/reports/FBgn0085591 protein_coding_gene - - - CG41274 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031452 Cwc25 Cwc25 http://flybase.org/reports/FBgn0031452 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "Cwc25, CG2843, CWC25" "IPR019339:CBF1-interacting co-repressor CIR, N-terminal domain, IPR022209:Pre-mRNA splicing factor" CG2843 27-Aug-18 DroID_v2018_08 Drer\cwc25 Scer\CWC25 Cele\mog-3 Xtro\cwc25 Mmus\Cwc25 Hsap\CWC25 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0266005 lncRNA:CR44779 - http://flybase.org/reports/FBgn0266005 non_protein_coding_gene - - - CR44779 - CR44779 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0083240 EP2204 EP2204 http://flybase.org/reports/FBgn0083240 gene - - - EP2204 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0021986 l(2)k09801 lethal (2) k09801 http://flybase.org/reports/FBgn0021986 - gene - - - "P918, l(2)k09801" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0041234 Gr59f Gustatory receptor 59f http://flybase.org/reports/FBgn0041234 protein_coding_gene taste receptor activity ; GO:0008527 | non-traceable author statement sensory perception of taste ; GO:0050909 | inferred from electronic annotation with InterPro:IPR013604 detection of chemical stimulus involved in sensory perception of taste ; GO:0050912 | non-traceable author statement integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 integral component of membrane ; GO:0016021 | non-traceable author statement "Gr59E1, CG5365, 59E.1, GR59E.1, CG33150, Gr59f" IPR013604:7TM chemoreceptor CG33150 27-Aug-18 DroID_v2018_08 "Drer\gstt2, Drer\gstt1b, Drer\gstr, Drer\mars, Drer\eef1g, Drer\vars, Drer\gstt1a, Drer\eef1e1" "Scer\CAM1, Scer\YGR201C, Scer\TEF4, Scer\GTT2, Scer\URE2, Scer\GTT1" - "Xtro\eef1e1, Xtro\eef1g, Xtro\gstt1" "Mmus\Gstt1, Mmus\Vars, Mmus\Gstt3, Mmus\Gstt4, Mmus\Gstt2, Mmus\Mars, Mmus\Eef1e1, Mmus\Eef1g" "Hsap\EEF1G, Hsap\GSTT2, Hsap\EEF1E1, Hsap\GSTT2B, Hsap\GSTT1, Hsap\MARS, Hsap\VARS" partially lethal - majority die FBgn0020581 anon-59Cd anon-59Cd http://flybase.org/reports/FBgn0020581 - gene - - - anon-59Cd - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0043026 l(2)42Fa lethal (2) 42Fa http://flybase.org/reports/FBgn0043026 gene - - - l(2)42Fa - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0266921 ft::Hsap\FAT4 - http://flybase.org/reports/FBgn0266921 engineered_fusion_gene - - - "ft::Hsap\FAT4, Fat:Fat4" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031513 CG3347 - http://flybase.org/reports/FBgn0031513 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001965 - - CG3347 "IPR011011:Zinc finger, FYVE/PHD-type, IPR019787:Zinc finger, PHD-finger, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR001965:Zinc finger, PHD-type, IPR019786:Zinc finger, PHD-type, conserved site" CG3347 27-Aug-18 DroID_v2018_08 "Drer\bptf, Drer\cxxc1b, Drer\cxxc1a" "Scer\SPP1, Scer\CTI6" Cele\cfp-1 "Xtro\cxxc1, Xtro\bptf" "Mmus\Cxxc1, Mmus\Bptf, Mmus\Dido1" "Hsap\CXXC1, Hsap\DIDO1, Hsap\BPTF" viable DRSC00597 K 0.007647223 -0.538442014 -0.702709217 0.05744939 -0.050026463 1.621872587 FBgn0259171 Pde9 Phosphodiesterase 9 http://flybase.org/reports/FBgn0259171 protein_coding_gene "3',5'-cyclic-nucleotide phosphodiesterase activity ; GO:0004114 | inferred from electronic annotation with InterPro:IPR002073 3',5'-cyclic-nucleotide phosphodiesterase activity ; GO:0004114 | inferred from sequence model" signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR002073 cyclic nucleotide metabolic process ; GO:0009187 | inferred from sequence model neurogenesis ; GO:0022008 | inferred from mutant phenotype - "CG42276, PDE9, CG32648, CG3765, CG3761, CG1627, Pde9, CG3754" "IPR002073:3'5'-cyclic nucleotide phosphodiesterase, catalytic domain, IPR003607:HD/PDEase domain, IPR023088:3'5'-cyclic nucleotide phosphodiesterase, IPR023174:3'5'-cyclic nucleotide phosphodiesterase, conserved site" CG42276 27-Aug-18 DroID_v2018_08 "Drer\LOC571737, Drer\pde4ba, Drer\pde11a, Drer\pde4bb, Drer\pde4a, Drer\pde5aa, Drer\pde6c, Drer\pde5ab, Drer\pde6b, Drer\pde10a, Drer\crtc1b, Drer\pde9a, Drer\pde6a, Drer\pde4ca, Drer\pde2a, Drer\pde4d, Drer\si:dkey-219c10.4, Drer\pde11al, Drer\pde9al, Drer\pde7a" Scer\PDE2 Cele\pde-6 "Xtro\pde7b, Xtro\pde6a, Xtro\pde4c, Xtro\pde2a, Xtro\pde5a, Xtro\pde7a, Xtro\pde4a, Xtro\LOC100493061, Xtro\pde6b, Xtro\pde9a, Xtro\pde10a, Xtro\pde11a, Xtro\pde4b, Xtro\pde4d, Xtro\pde6c" "Mmus\Pde10a, Mmus\Pde9a, Mmus\Pde2a, Mmus\Pde6b, Mmus\Pde8a, Mmus\Pde11a, Mmus\Pde4b, Mmus\Pde8b, Mmus\Pde4a, Mmus\Pde7b, Mmus\Pde5a, Mmus\Pde7a, Mmus\Pde6a, Mmus\Pde4d, Mmus\Pde6c, Mmus\Pde4c" "Hsap\PDE4D, Hsap\PDE10A, Hsap\PDE2A, Hsap\PDE8B, Hsap\PDE4C, Hsap\PDE7A, Hsap\PDE6B, Hsap\PDE6C, Hsap\PDE9A, Hsap\PDE4B, Hsap\PDE4A, Hsap\PDE5A, Hsap\PDE6A, Hsap\PDE11A, Hsap\PDE8A, Hsap\PDE7B" FBgn0038529 CG14323 - http://flybase.org/reports/FBgn0038529 protein_coding_gene - - - CG14323 - CG14323 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC14802 E -0.68520201 -0.081526843 1.966632417 0.21844102 -0.279816649 0.157506215 FBgn0050443 Opbp Optix-binding protein http://flybase.org/reports/FBgn0050443 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - "Obp, OBP, CG12397, BcDNA:RE37461, CG30443, Opbp" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG30443 27-Aug-18 DroID_v2018_08 "Drer\LOC100001832, Drer\znf1161, Drer\znf143a, Drer\zgc:113295, Drer\zgc:113030, Drer\zgc:113377, Drer\LOC100537377, Drer\zgc:113343, Drer\LOC798256, Drer\zgc:153116, Drer\blf, Drer\LOC103908714, Drer\znf1157, Drer\si:dkey-1b17.8, Drer\LOC101885996, Drer\LOC100333228, Drer\si:rp71-1h20.5, Drer\LOC100534908, Drer\zgc:110249, Drer\si:ch73-367f21.6, Drer\si:ch211-202h22.10, Drer\LOC100535934, Drer\zgc:174288, Drer\si:ch211-155e24.3, Drer\si:ch211-161m3.4, Drer\zgc:163077, Drer\si:ch211-241e1.5, Drer\zgc:162936, Drer\zgc:113348, Drer\znf407, Drer\LOC101883936, Drer\si:dkey-226l10.6, Drer\LOC100535458, Drer\zgc:175107, Drer\klf1, Drer\zgc:171551, Drer\si:ch73-367f21.4, Drer\si:ch73-299h12.4, Drer\si:dkeyp-53d3.3, Drer\znf1178, Drer\LOC101886221, Drer\si:ch73-299h12.6, Drer\znf995, Drer\znf1154, Drer\LOC100537687, Drer\si:ch211-110e21.4, Drer\zgc:194336, Drer\LOC101884416, Drer\zgc:171220, Drer\si:dkey-210j14.3, Drer\znf971, Drer\LOC101884439, Drer\si:dkey-253d23.8, Drer\zgc:174263, Drer\si:dkeyp-68b7.7, Drer\LOC103910593, Drer\si:ch211-161m3.2, Drer\LOC100002469, Drer\znf143b, Drer\si:ch211-222k6.1, Drer\pogza, Drer\znf970, Drer\si:dkey-15h8.16, Drer\si:ch1073-127d16.1, Drer\zgc:113294, Drer\si:ch73-138e16.4" Scer\AZF1 "Cele\che-1, Cele\hinf-1, Cele\Y55F3AM.14, Cele\zfp-2, Cele\ces-1" "Xtro\znf143, Xtro\zxdc, Xtro\znf280d" "Mmus\Prdm9, Mmus\Zfp27, Mmus\Zfp280b, Mmus\Prdm4, Mmus\Zfp422, Mmus\Zfp26, Mmus\Zfp143, Mmus\Zfp808, Mmus\Zbtb24, Mmus\Pogz, Mmus\Zfp275, Mmus\Zfp280d, Mmus\Zfp280c, Mmus\Zfp523" "Hsap\ZNF808, Hsap\ZNF619, Hsap\ZNF583, Hsap\ZNF813, Hsap\POGZ, Hsap\ZNF280A, Hsap\ZNF765, Hsap\ZXDA, Hsap\ZNF280B, Hsap\ZNF280C, Hsap\ZNF418, Hsap\ZNF22, Hsap\ZNF76, Hsap\ZNF468, Hsap\ZNF280D, Hsap\ZNF17, Hsap\ZNF143, Hsap\ZXDB" "viable,fertile" FBgn0260375 GSd446 - http://flybase.org/reports/FBgn0260375 gene - - - GSd446 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve,segmental nerve" FBgn0285912 mah mahogany http://flybase.org/reports/FBgn0285912 protein_coding_gene amino acid transmembrane transporter activity ; GO:0015171 | inferred from sequence or structural similarity with Eaat1 amino acid transmembrane transport ; GO:0003333 | inferred from sequence or structural similarity with Eaat1 - "mah, CG13646" "IPR013057:Amino acid transporter, transmembrane domain" CG13646 27-Aug-18 DroID_v2018_08 "Drer\slc32a1, Drer\si:dkey-126h10.1" - "Cele\Y4C6B.2, Cele\R02F2.8, Cele\Y59H11AR.4, Cele\Y18D10A.23, Cele\F21D12.3, Cele\unc-47, Cele\Y32F6A.4" - Mmus\Slc32a1 Hsap\SLC32A1 viable FBgn0025135 su(RpII140[Z36])S12 su(RpII140[Z36])S12 http://flybase.org/reports/FBgn0025135 - gene - - - "Z36[S12], su(RpII140[Z36])S12" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0082999 snoRNA:Psi28S-1192c snoRNA:Psi28S-1192c http://flybase.org/reports/FBgn0082999 snoRNA_gene - - - "snoRNA:Psi28S-1192c, Psi28S-1192c, psi28S-1192c, CR34595" - CR34595 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065639 l(2)SH0762 lethal (2) SH0762 http://flybase.org/reports/FBgn0065639 gene - - - "l(2)SH0762, l(2)SH2 0762" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0017482 T3dh Type III alcohol dehydrogenase http://flybase.org/reports/FBgn0017482 - protein_coding_gene metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR001670 hydroxyacid-oxoacid transhydrogenase activity ; GO:0047988 | inferred from sequence or structural similarity with UniProtKB:Q8IWW8 alcohol dehydrogenase (NAD) activity ; GO:0004022 | inferred from biological aspect of ancestor with PANTHER:PTN001691340 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001670 molecular hydrogen transport ; GO:0015993 | inferred from sequence or structural similarity with UniProtKB:Q8IWW8 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000161036 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN001691340 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q8R0N6 "CG3425, T3dh" "IPR001670:Alcohol dehydrogenase, iron-type" CG3425 27-Aug-18 DroID_v2018_08 Drer\adhfe1 Scer\ADH4 Cele\Y38F1A.6 Xtro\adhfe1 Mmus\Adhfe1 Hsap\ADHFE1 "viable,fertile,visible" trichogen cell FBgn0001416 l(1)5CDa lethal (1) 5CDa http://flybase.org/reports/FBgn0001416 - gene - - - "ts155, l(1)ts155, l(1)E12, l(1)5CDa" - - 27-Aug-18 DroID_v2018_08 - - - - - - "sterile,recessive,heat sensitive,lethal - all die before end of pupal stage,some die during pupal stage,chemical sensitive" FBgn0031607 CG15440 - http://flybase.org/reports/FBgn0031607 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 - - "cg15440, CG15440, Secp43" "IPR000504:RNA recognition motif domain, IPR034510:SECp43, RNA recognition motif 2" CG15440 27-Aug-18 DroID_v2018_08 "Drer\hnrnpd, Drer\rbm34, Drer\nono, Drer\hnrnpc, Drer\hnrnpabb, Drer\zgc:55733, Drer\zcrb1, Drer\tia1l, Drer\raly, Drer\cirbpa, Drer\trnau1apa, Drer\eif4h, Drer\hnrnpaba, Drer\sfpq, Drer\eif4ba, Drer\tial1, Drer\srsf10a, Drer\dazl, Drer\tia1, Drer\ncoa5, Drer\hnrnpa1b, Drer\wu:fq32h04, Drer\hnrnpa3, Drer\trnau1apb" "Scer\NOP6, Scer\MRN1, Scer\NAB6, Scer\NOP12, Scer\CWC2, Scer\NAM8, Scer\MUD1, Scer\PUB1, Scer\NGR1" "Cele\tiar-1, Cele\T07F10.3" "Xtro\rbm34, Xtro\ralyl, Xtro\trnau1ap, Xtro\dazl, Xtro\tia1, Xtro\eif4b, Xtro\hnrnpd, Xtro\hnrnpa3, Xtro\cirbp, Xtro\eif4h, Xtro\hnrnpa2b1, Xtro\sfpq, Xtro\hnrnpdl, Xtro\hnrnpa1, Xtro\hnrnpc, Xtro\raly, Xtro\hnrnpab" "Mmus\Srsf10, Mmus\Srsf12, Mmus\Boll, Mmus\Eif4b, Mmus\Slirp, Mmus\Eif4h, Mmus\Hnrnpa1, Mmus\Hnrnpa2b1, Mmus\Hnrnpa3, Mmus\Hnrnpab, Mmus\Rbm31y, Mmus\Hnrnpc, Mmus\Rbm34, Mmus\Trnau1ap, Mmus\Gm21379, Mmus\Raly, Mmus\Tia1, Mmus\Sfpq, Mmus\Tial1, Mmus\Hnrnpd, Mmus\Tra2b, Mmus\Pspc1, Mmus\Dazl, Mmus\Cirbp, Mmus\Zcrb1" "Hsap\BOLL, Hsap\DAZ2, Hsap\HNRNPA2B1, Hsap\SFPQ, Hsap\SRSF10, Hsap\HNRNPA1L2, Hsap\EIF4B, Hsap\RALYL, Hsap\RBM3, Hsap\C6orf52, Hsap\TIAL1, Hsap\DAZL, Hsap\HNRNPC, Hsap\DAZ1, Hsap\HNRNPA1, Hsap\HNRNPAB, Hsap\RALY, Hsap\HNRNPD, Hsap\TIA1, Hsap\RBM34, Hsap\DAZ3, Hsap\SLIRP, Hsap\PSPC1, Hsap\HNRNPA3, Hsap\DAZ4, Hsap\CIRBP, Hsap\TRNAU1AP, Hsap\EIF4H, Hsap\HNRNPCL1" "partially lethal - majority die,body color defective" mesothoracic tergum FBgn0001084 fy fuzzy http://flybase.org/reports/FBgn0001084 - protein_coding_gene - establishment of imaginal disc-derived wing hair orientation ; GO:0001737 | traceable author statement establishment or maintenance of cell polarity ; GO:0007163 | inferred from mutant phenotype establishment of planar polarity ; GO:0001736 | traceable author statement - "CG13396, fy" IPR026069:Fuzzy protein CG13396 27-Aug-18 DroID_v2018_08 Drer\fuz - - Xtro\fuz Mmus\Fuz Hsap\FUZ embryonic stage -- adult stage organism

"wild-type,planar polarity defective,viable,visible,recessive" "wing hair,wing hair & 1st posterior cell,wing hair & 3rd posterior cell,wing & trichome,wing cell,macrochaeta,microchaeta & adult thorax,wing margin bristle,microchaeta & leg,bract,trichome,trichogen cell" DRSC03533 K -0.677267405 -0.128713273 -0.429033216 0.283398489 1.524777308 -0.528743578 FBgn0030228 BTBD9 BTB (POZ) domain containing 9 http://flybase.org/reports/FBgn0030228 protein_coding_gene "ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 protein binding, bridging ; GO:0030674 | inferred from sequence or structural similarity with PDB:3HVE" "adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype regulation of synaptic transmission, dopaminergic ; GO:0032225 | inferred from mutant phenotype protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 positive regulation of circadian sleep/wake cycle, sleep ; GO:0045938 | inferred from mutant phenotype regulation of proteolysis ; GO:0030162 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN000698504" cytoplasm ; GO:0005737 | inferred from direct assay Cul3-RING ubiquitin ligase complex ; GO:0031463 | inferred from sequence or structural similarity with PDB:3HVE SCF ubiquitin ligase complex ; GO:0019005 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 "BTBD9, dBTBD9, CG1826" "IPR000210:BTB/POZ domain, IPR008979:Galactose-binding domain-like, IPR011705:BTB/Kelch-associated, IPR011333:SKP1/BTB/POZ domain, IPR034091:BTBD9, BACK-like domain, IPR000421:Coagulation factor 5/8 C-terminal domain" CG1826 27-Aug-18 DroID_v2018_08 Drer\btbd9 Scer\YIL001W Cele\hpo-9 "Xtro\klhl41, Xtro\btbd9" Mmus\Btbd9 "Hsap\BTBD9, Hsap\BTBD19" "viable,short lived,sleep defective,recessive,locomotor behavior defective" DRSC22371 K -0.44672001 0.1189548 -0.571569764 -0.267415836 -1.553329981 -0.269928017 FBgn0038057 CG12267 - http://flybase.org/reports/FBgn0038057 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR008806 RNA polymerase III activity ; GO:0001056 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000310442 "transcription, DNA-templated ; GO:0006351 | inferred from electronic annotation with InterPro:IPR008806" DNA-directed RNA polymerase III complex ; GO:0005666 | inferred from biological aspect of ancestor with PANTHER:PTN000310442 CG12267 "IPR008806:RNA polymerase III Rpc82, C -terminal, IPR013197:RNA polymerase III subunit RPC82-related, helix-turn-helix, IPR011991:Winged helix-turn-helix DNA-binding domain" CG12267 27-Aug-18 DroID_v2018_08 Drer\polr3c Scer\RPC82 Cele\let-611 Xtro\polr3c Mmus\Polr3c Hsap\POLR3C "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0264629 asthmatic asthmatic http://flybase.org/reports/FBgn0264629 gene - "trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - asthmatic - - 27-Aug-18 DroID_v2018_08 - - - - - - "eye,somatic clone,terminal tracheal cell,embryonic/larval tracheal system" FBgn0050287 CG30287 - http://flybase.org/reports/FBgn0050287 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - "SP37, SPH37, CG10450, CG30287" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG30287 27-Aug-18 DroID_v2018_08 "Drer\si:dkeyp-93a5.3, Drer\zgc:165423, Drer\gzmk, Drer\zgc:163079, Drer\si:ch211-165b19.9, Drer\ovch1, Drer\masp2, Drer\si:ch211-165b19.8, Drer\zgc:92313, Drer\gzma, Drer\gzm3, Drer\si:dkey-16l2.17, Drer\si:ch211-165b19.5, Drer\f9a, Drer\LOC558805, Drer\LOC100004427, Drer\cfd" - "Cele\try-1, Cele\try-3, Cele\svh-1, Cele\try-6" - "Mmus\Klk15, Mmus\Tmprss12, Mmus\Klk1b9, Mmus\Klk9, Mmus\Egfbp2, Mmus\Klk1b5" "Hsap\TMPRSS12, Hsap\KLK9, Hsap\MASP1, Hsap\KLK15" FBgn0029769 frma fra mauro http://flybase.org/reports/FBgn0029769 protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR018497" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR008753, InterPro:IPR018497 negative regulation of female receptivity, post-mating ; GO:0045434 | inferred from mutant phenotype" - "BEST:GH09377, CG3239, frma" "IPR000718:Peptidase M13, IPR018497:Peptidase M13, C-terminal domain, IPR024079:Metallopeptidase, catalytic domain, IPR008753:Peptidase M13, N-terminal domain" CG3239 27-Aug-18 DroID_v2018_08 "Drer\mmel1, Drer\phex, Drer\ece2b, Drer\ece1" - "Cele\nep-18, Cele\nep-16, Cele\nep-21, Cele\nep-7, Cele\nep-8, Cele\nep-24, Cele\nep-19, Cele\nep-13, Cele\nep-6, Cele\nep-20, Cele\nep-10, Cele\nep-12, Cele\nep-5, Cele\nep-26, Cele\nep-9, Cele\nep-23, Cele\nep-3, Cele\nep-17" "Xtro\ece2, Xtro\mmel1, Xtro\ecel1, Xtro\ece1" "Mmus\Ece1, Mmus\Ece2, Mmus\Mme, Mmus\Ecel1, Mmus\Kel, Mmus\Mmel1, Mmus\Phex" "Hsap\MME, Hsap\MMEL1, Hsap\ECE2, Hsap\PHEX, Hsap\KEL, Hsap\ECEL1, Hsap\ECE1" "mating behavior defective,female limited,female semi-fertile" FBgn0039726 eIF2Balpha eukaryotic translation initiation factor 2B subunit alpha http://flybase.org/reports/FBgn0039726 protein_coding_gene translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity with SGD:S000001734 translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity enzyme regulator activity ; GO:0030234 | inferred from genetic interaction with SGD:S000001734 translational initiation ; GO:0006413 | inferred from sequence or structural similarity with SGD:S000001734 lateral inhibition ; GO:0046331 | inferred from mutant phenotype translational initiation ; GO:0006413 | inferred from sequence or structural similarity cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000027918 eukaryotic translation initiation factor 2B complex ; GO:0005851 | inferred from sequence or structural similarity eukaryotic translation initiation factor 2B complex ; GO:0005851 | inferred from sequence or structural similarity with SGD:S000001734 cytosol ; GO:0005829 | inferred from sequence or structural similarity "CG7883, DeIF2Balpha, eIF2B-alpha, Eif2b, eIF2Balpha" IPR000649:Initiation factor 2B-related CG7883 27-Aug-18 DroID_v2018_08 Drer\eif2b1 Scer\GCN3 "Cele\F11A3.2, Cele\ZK1098.4" Xtro\eif2b1 Mmus\Eif2b1 Hsap\EIF2B1 "viable,visible" "chaeta,trichogen cell" FBgn0029863 CG3823 - http://flybase.org/reports/FBgn0029863 protein_coding_gene transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR001071 transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR001071 intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR001071 CG3823 "IPR001071:Cellular retinaldehyde binding/alpha-tocopherol transport, IPR001251:CRAL-TRIO lipid binding domain, IPR011074:CRAL/TRIO, N-terminal domain" CG3823 27-Aug-18 DroID_v2018_08 "Drer\clvs2, Drer\sec14l8, Drer\ttpa, Drer\rlbp1b, Drer\sec14l7, Drer\rlbp1a, Drer\ttpal" "Scer\YKL091C, Scer\SFH5, Scer\SEC14" - "Xtro\sec14l1, Xtro\clvs2, Xtro\mospd2, Xtro\sec14l3, Xtro\sec14l5, Xtro\clvs1, Xtro\ttpal, Xtro\ttpa, Xtro\rlbp1" "Mmus\Sec14l3, Mmus\Sec14l5, Mmus\Sec14l1, Mmus\Sec14l2, Mmus\Clvs2, Mmus\Sec14l4, Mmus\Ttpa, Mmus\Rlbp1, Mmus\Clvs1, Mmus\Ttpal" "Hsap\CLVS2, Hsap\SEC14L6, Hsap\SEC14L2, Hsap\SEC14L4, Hsap\CLVS1, Hsap\TTPAL, Hsap\SEC14L5, Hsap\SEC14L1, Hsap\RLBP1, Hsap\SEC14L3, Hsap\TTPA" "viable,fertile" FBgn0022745 anon-J1b anon-J1b http://flybase.org/reports/FBgn0022745 - gene - - - "J1, anon-J1b" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040004 CG12552 - http://flybase.org/reports/FBgn0040004 protein_coding_gene - - - CG12552 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263995 cpo couch potato http://flybase.org/reports/FBgn0263995 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity dormancy process ; GO:0022611 | inferred from mutant phenotype detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype regulation of hemocyte proliferation ; GO:0035206 | inferred from mutant phenotype chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype olfactory behavior ; GO:0042048 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "cpo, CPO, CG43738, CG31243, ORE-17, CG12349, CG18435, cg18435, Cpo, l(3)6015, 6015, 5339, 3603, 1824, l(3)s2336, l(3)rJ553, l(3)j9B3, l(3)j7E2, l(3)j4D4, l(3)j4A1, l(3)01432, E(sda)N, CG18434, BcDNA:AT31405, Line N, CG42457" IPR000504:RNA recognition motif domain CG43738 27-Aug-18 DroID_v2018_08 "Drer\rbpms2a, Drer\LOC100537153, Drer\rbpms2b" "Scer\WHI3, Scer\WHI4, Scer\YGR250C" "Cele\mec-8, Cele\rsp-2" Xtro\rbpms "Mmus\Rbpms2, Mmus\Rbpms" "Hsap\RBPMS2, Hsap\RBPMS" embryonic stage " neuron &&of chordotonal organ

, embryonic peripheral nervous system

" embryonic stage " central nervous system

{ 0 AS-C- } , peripheral nervous system

, glial cell

, neuron chordotonal organ

{ 0 AS-C- } , sensory organ mother cell

{ - da* } , posterior spiracle

{ - AS-C- } , central nervous system

{ $ da* } , peripheral nervous system

{ 0 AS-C- } , peripheral nervous system

{ 0 da* } , embryonic central nervous system

, neuron

, embryonic/larval midgut

, midgut

{ 0 da* } , glial cell

{ 0 AS-C- } , midgut

" DRSC13265 I 1.374389261 1.553335766 -0.049318037 -0.250038696 -0.012647936 -0.182963195 FBgn0263960 BG01677 - http://flybase.org/reports/FBgn0263960 gene - - - BG01677 - - 27-Aug-18 DroID_v2018_08 - - - - - - "long lived,starvation stress response defective,male limited" FBgn0036812 Nufip Nufip http://flybase.org/reports/FBgn0036812 protein_coding_gene snoRNA binding ; GO:0030515 | inferred from biological aspect of ancestor with PANTHER:PTN000329871 box C/D snoRNP assembly ; GO:0000492 | inferred from biological aspect of ancestor with PANTHER:PTN000329871 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000329871 "CG4076, NUFIP, Nufip" "IPR019496:Nuclear fragile X mental retardation-interacting protein 1, conserved domain" CG4076 27-Aug-18 DroID_v2018_08 Drer\nufip1 - - Xtro\nufip1 Mmus\Nufip1 Hsap\NUFIP1 "viable,visible,lethal - all die before end of pupal stage" trichogen cell FBgn0052431 CG32431 - http://flybase.org/reports/FBgn0052431 protein_coding_gene - - - CG32431 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000796 fs(1)de7 female sterile (1) defective eggs 7 http://flybase.org/reports/FBgn0000796 - gene - - - "de7, fs(1)de7" - - 27-Aug-18 DroID_v2018_08 - - - - - - female sterile "dorsal appendage,chorion" FBgn0004505 fs(1)A5 female sterile (1) A5 http://flybase.org/reports/FBgn0004505 - gene - - - fs(1)A5 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0015454 l(2)24CDa lethal (2) 24CDa http://flybase.org/reports/FBgn0015454 - gene - - - "l(2)d, l(2)24CDa" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0039169 Spps Sp1-like factor for pairing sensitive-silencing http://flybase.org/reports/FBgn0039169 protein_coding_gene "RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN001145452 sequence-specific DNA binding ; GO:0043565 | inferred from direct assay" regulation of gene silencing ; GO:0060968 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001145452 nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001145452 polytene chromosome band ; GO:0005704 | inferred from direct assay "CG5669, Spps" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR032675:Leucine-rich repeat domain, L domain-like" CG5669 27-Aug-18 DroID_v2018_08 "Drer\sp3b, Drer\sp5a, Drer\klf11b, Drer\sp1, Drer\sp8a, Drer\klf5a, Drer\sp9, Drer\zeb1a, Drer\klf5l, Drer\zgc:153115, Drer\sp7, Drer\zgc:77358, Drer\sp8b, Drer\sp4, Drer\sp3a, Drer\sp5l, Drer\sp5b, Drer\sp2, Drer\klf13" "Scer\CRZ1, Scer\SWI5, Scer\ACE2" "Cele\ZK686.5, Cele\sptf-1, Cele\sptf-3, Cele\klf-2, Cele\sptf-2" "Xtro\sp3, Xtro\sp7, Xtro\sp5, Xtro\sp6, Xtro\sp1, Xtro\sp2, Xtro\sp5l, Xtro\sp4" "Mmus\Sp7, Mmus\Sp9, Mmus\Sp6, Mmus\Sp8, Mmus\Sp5, Mmus\Sp1, Mmus\Sp3, Mmus\Klf5, Mmus\Klf13, Mmus\Klf10, Mmus\Sp4, Mmus\Sp2" "Hsap\SP9, Hsap\SP4, Hsap\SP2, Hsap\SP5, Hsap\SP8, Hsap\KLF10, Hsap\SP3, Hsap\SP7, Hsap\SP6, Hsap\SP1, Hsap\KLF13" "lethal,recessive,germline clone,penetrance incomplete (obsolete FBcv0000019),partially lethal - majority die,lethal - all die before end of P-stage,some die during pharate adult stage,viable,visible" "wing,mesothoracic tergum" FBgn0003108 pallid pallid http://flybase.org/reports/FBgn0003108 - gene - - - "pl, pallid, pld" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority live,body color defective" wing FBgn0036814 CG14073 - http://flybase.org/reports/FBgn0036814 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap" - "Nirvana, CG14073" "IPR002110:Ankyrin repeat, IPR020683:Ankyrin repeat-containing domain" CG14073 27-Aug-18 DroID_v2018_08 "Drer\ankrd31, Drer\cdkn2c, Drer\bcor, Drer\bcorl1" "Scer\HOS4, Scer\YAR1" "Cele\frm-9, Cele\K02B12.5" "Xtro\bcor, Xtro\bcorl1" "Mmus\Cdkn2c, Mmus\Cdkn2d, Mmus\Bcorl1, Mmus\Bcor" "Hsap\BCORL1, Hsap\CDKN2D, Hsap\CDKN2C, Hsap\BCOR" viable FBgn0002463 l(3)SG16 lethal (3) SG16 http://flybase.org/reports/FBgn0002463 - gene - - - l(3)SG16 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0032817 CG10631 - http://flybase.org/reports/FBgn0032817 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR006612 - - CG10631 "IPR006612:Zinc finger, C2CH-type, IPR013087:Zinc finger C2H2-type" CG10631 27-Aug-18 DroID_v2018_08 "Drer\znf574, Drer\znf710a, Drer\znf366, Drer\znf710b" - "Cele\ztf-29, Cele\zag-1" - "Mmus\Zfp366, Mmus\Zfp710" "Hsap\ZNF710, Hsap\ZNF366" viable FBgn0019740 l(1)91-1 lethal (1) 91-1 http://flybase.org/reports/FBgn0019740 - gene - - - l(1)91-1 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0259302 EP-108 - http://flybase.org/reports/FBgn0259302 gene - - - EP-108 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing vein,wing margin,chaeta" FBgn0044079 E(rst)H65 E(rst)H65 http://flybase.org/reports/FBgn0044079 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "H65, E(rst)H65" - - 27-Aug-18 DroID_v2018_08 - - - - - - viable eye FBgn0267030 lncRNA:CR45474 - http://flybase.org/reports/FBgn0267030 non_protein_coding_gene - - - CR45474 - CR45474 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0010243 Mst77F-PsiY1 Mst77F pseudogene on Y 1 http://flybase.org/reports/FBgn0010243 - pseudogene_attribute - - - "18c, Mst77F-PsiY1, Mst77-Psi1" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030190 CG2908 - http://flybase.org/reports/FBgn0030190 protein_coding_gene - - - CG2908 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263851 snoRNA:CD-24 - http://flybase.org/reports/FBgn0263851 snoRNA_gene - - - "snoRNA:CD-24, snoCD_24, CR43712" - CR43712 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0042697 N-fa-swb-INS Notch facet strawberry insulator element http://flybase.org/reports/FBgn0042697 insulator - - - "Fa[swb], fa[swb], N-fa-swb-INS" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005465 l(1)ts88 lethal (1) ts88 http://flybase.org/reports/FBgn0005465 - gene - - - l(1)ts88 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,heat sensitive,female sterile" FBgn0039806 CG15545 - http://flybase.org/reports/FBgn0039806 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15545 - CG15545 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051488 CG31488 - http://flybase.org/reports/FBgn0051488 protein_coding_gene - - - CG31488 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040806 CG13456 - http://flybase.org/reports/FBgn0040806 protein_coding_gene - - - CG13456 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265077 lncRNA:CR44188 - http://flybase.org/reports/FBgn0265077 non_protein_coding_gene - - - CR44188 - CR44188 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262653 l(3)ED220-1 - http://flybase.org/reports/FBgn0262653 gene - - - l(3)ED220-1 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of P-stage,recessive,some die during P-stage,lethal" FBgn0031985 mon2 monensin sensitivity 2 http://flybase.org/reports/FBgn0031985 protein_coding_gene cytoskeletal regulatory protein binding ; GO:0005519 | inferred from physical interaction with spir pole plasm protein localization ; GO:0007318 | inferred from mutant phenotype actin cytoskeleton reorganization ; GO:0031532 | inferred from mutant phenotype endosome ; GO:0005768 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay "CG31756, CG14276, CG8683, mon2, noan, Mon2" "IPR015403:Sec7, C-terminal, IPR032817:Mon2, C-terminal, IPR032691:Guanine nucleotide exchange factor, N-terminal, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold, IPR032629:Mon2, dimerisation and cyclophilin-binding domain" CG8683 27-Aug-18 DroID_v2018_08 Drer\mon2 Scer\MON2 Cele\mon-2 Xtro\mon2 Mmus\Mon2 Hsap\MON2 "viable,body color defective" mesothoracic tergum FBgn0016887 l(2)39DEl lethal (2) 39DEl http://flybase.org/reports/FBgn0016887 - gene - - - "K234, l(2)39DEl" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0061516 cri criss-cross http://flybase.org/reports/FBgn0061516 gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available cri - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "embryonic head,embryonic abdominal segment 4,embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic abdominal segment 7,embryonic abdominal segment 8,embryonic epidermis,denticle belt" FBgn0032077 CG9515 - http://flybase.org/reports/FBgn0032077 protein_coding_gene nucleoside-triphosphate diphosphatase activity ; GO:0047429 | inferred from electronic annotation with InterPro:IPR003697 - - "gh06087, CG33085, BEST:GH06087, CG9515" "IPR003697:Maf-like protein, IPR029001:Inosine triphosphate pyrophosphatase-like" CG9515 27-Aug-18 DroID_v2018_08 "Drer\asmt2, Drer\asmtl, Drer\asmt" Scer\YOR111W Cele\dod-18 "Xtro\asmt, Xtro\asmtl" Mmus\Asmt "Hsap\ASMT, Hsap\ASMTL" "viable,fertile" FBgn0004963 abg ambiguous http://flybase.org/reports/FBgn0004963 - gene molecular_function ; GO:0003674 | no biological data available cuticle pattern formation ; GO:0035017 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available abg - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal - all die before end of larval stage,some die during larval stage,lethal,rescuable maternal effect" "embryonic epidermis,germline clone,embryonic/first instar larval cuticle,ovary" FBgn0262024 CG42835 - http://flybase.org/reports/FBgn0262024 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42835 - CG42835 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0020226 Calp14B Calpain 14B http://flybase.org/reports/FBgn0020226 - gene - - - Calp14B - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031055 et eye transformer http://flybase.org/reports/FBgn0031055 protein_coding_gene cytokine receptor activity ; GO:0004896 | inferred from electronic annotation with InterPro:IPR003529 protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with dome receptor activity ; GO:0004872 | inferred from sequence or structural similarity with dome defense response to bacterium ; GO:0042742 | inferred from mutant phenotype negative regulation of tyrosine phosphorylation of STAT protein ; GO:0042532 | inferred from mutant phenotype negative regulation of JAK-STAT cascade ; GO:0046426 | inferred from direct assay membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR003529 "CG14225, et, ET, lat" "IPR003529:Long hematopoietin receptor, Gp130 family 2, conserved site, IPR003961:Fibronectin type III, IPR013783:Immunoglobulin-like fold" CG14225 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile,stress response defective,RU486 conditional" "lamellocyte,wing,eye" FBgn0003679 te tenerchaetae http://flybase.org/reports/FBgn0003679 - gene - - - te - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive,viable,good,male,male sterile,female sterile,eye color defective" "macrochaeta,wing,wing vein,pigment cell,eye" FBgn0086061 snoRNA:Or-CD8 - http://flybase.org/reports/FBgn0086061 snoRNA_gene - - - "snoRNA:Or-CD8, orphan CD8, DmOr_cd8, CR34690" - CR34690 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0250830 CG12547 - http://flybase.org/reports/FBgn0250830 protein_coding_gene - - - "CG40277, CG12547, anon-EST:Posey268" "IPR011042:Six-bladed beta-propeller, TolB-like, IPR012336:Thioredoxin-like fold, IPR013017:NHL repeat, subgroup, IPR001258:NHL repeat" CG12547 27-Aug-18 DroID_v2018_08 Drer\nhlrc2 - Cele\nhl-1 Xtro\nhlrc2 Mmus\Nhlrc2 Hsap\NHLRC2 FBgn0019921 T:nls-Sry-delta nuclear localisation signal of Sry-delta http://flybase.org/reports/FBgn0019921 - engineered_tag - - - "T:nls-Sry-delta, T:nls3" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005315 mu-F mutator from Florida http://flybase.org/reports/FBgn0005315 - gene - - - mu-F - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000276 CecA1 Cecropin A1 http://flybase.org/reports/FBgn0000276 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available defense response to Gram-negative bacterium ; GO:0050829 | inferred from direct assay defense response to Gram-positive bacterium ; GO:0050830 | inferred from direct assay defense response to Gram-negative bacterium ; GO:0050829 | inferred from expression pattern defense response to bacterium ; GO:0042742 | traceable author statement autophagic cell death ; GO:0048102 | inferred from expression pattern salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern antibacterial humoral response ; GO:0019731 | inferred from expression pattern AND inferred from sequence or structural similarity antibacterial humoral response ; GO:0019731 | inferred from direct assay antibacterial humoral response ; GO:0019731 | inferred from expression pattern humoral immune response ; GO:0006959 | inferred from expression pattern response to bacterium ; GO:0009617 | inferred from expression pattern extracellular region ; GO:0005576 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay "CecA1, Cecropin A1, Cec, CEC, CecA, cec, CG1365, cecA1, cecA, Cec A1, crpA1, DIM 25, Cec-A1" "IPR000875:Cecropin, IPR020400:Cecropin, diptera" CG1365 27-Aug-18 DroID_v2018_08 - - - - - - " pupal stage , larval stage , adult stage " " embryonic/larval hemocyte

, adult fat body

" "viable,body color defective" "adult posterior midgut epithelium,mesothoracic tergum" FBgn0011105 l(1)Q66 lethal (1) Q66 http://flybase.org/reports/FBgn0011105 FBgn0010210 gene - - - l(1)Q66 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0060548 l(3)S098516a lethal (3) S098516a http://flybase.org/reports/FBgn0060548 gene - - - "0985/16, l(3)S098516a" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0086449 Cog8 - http://flybase.org/reports/FBgn0086449 gene - - - Cog8 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263555 mir-4943 mir-4943 stem loop http://flybase.org/reports/FBgn0263555 miRNA_gene - - - "mir-4943, dme-mir-4943, CR43540" - CR43540 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040605 CG14236 - http://flybase.org/reports/FBgn0040605 protein_coding_gene - - - CG14236 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000758 fs(1)A462 female sterile (1) A462 http://flybase.org/reports/FBgn0000758 - gene - - - "fs(1)462, fs(1)A462" - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile soma-dependent,recessive" FBgn0011855 tRNA:Glu-CTC-3-9 transfer RNA:Glutamic acid-CTC 3-9 http://flybase.org/reports/FBgn0011855 "FBgn0003768, FBgn0003772, FBgn0011846, FBgn0052322, FBgn0060245" tRNA_gene GAG codon-amino acid adaptor activity ; GO:0033460 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033460 cytosol ; GO:0005829 | inferred by curator from GO:0033460 "glu-trna, AE002584.trna11-GluCTC, tRNA:E4, tRNA:E:CTC:AE002584-i, tRNA:glu4:62Ae, CR32322, tRNA:Glu, chr3L.trna11-GluCTC, tRNA:Glu-CTC-3-9, tRNA:E4:62Ae, tRNA-Glu-CTC-3-9, GAG" - CR32322 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0028138 l(3)S048318 lethal (3) S048318 http://flybase.org/reports/FBgn0028138 gene - - - "0483/18, l(3)S048318" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0264467 asRNA:CR43875 - http://flybase.org/reports/FBgn0264467 non_protein_coding_gene - - - CR43875 - CR43875 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0069249 attP:Dps2 pseudo attP recognition site Dps2 http://flybase.org/reports/FBgn0069249 region - - - attP:Dps2 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267249 lncRNA:CR45689 - http://flybase.org/reports/FBgn0267249 non_protein_coding_gene - - - CR45689 - CR45689 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0010651 MFS14 Major Facilitator Superfamily Transporter 14 http://flybase.org/reports/FBgn0010651 FBgn0034393 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 "wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 anion transport ; GO:0006820 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 response to hypoxia ; GO:0001666 | inferred from expression pattern inferred from mutant phenotype" integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 plasma membrane ; GO:0005886 | inferred from direct assay "CG15095, 8717, MFS14, l(2)08717, lethal (2) 08717, lethal(2)08717, l208717" "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG15095 27-Aug-18 DroID_v2018_08 "Drer\ppt1, Drer\si:ch1073-513e17.1, Drer\slc17a9a, Drer\slc17a5, Drer\slc17a8, Drer\slc17a6a, Drer\slc17a7a, Drer\slc17a6b" "Scer\YIL166C, Scer\DAL5, Scer\THI73, Scer\TNA1" "Cele\T02B11.6, Cele\T19D12.9, Cele\vglu-3, Cele\Y15E3A.4, Cele\F10C2.7, Cele\C01B4.7, Cele\slc-17.5, Cele\C01B4.8, Cele\slc-17.4, Cele\C18H9.5, Cele\F11A5.9, Cele\eat-4, Cele\C18D1.2, Cele\slc-17.2, Cele\F41C3.2, Cele\Y19D10A.11, Cele\T22F3.11, Cele\Y19D10A.5, Cele\F56A4.12, Cele\slc-17.3, Cele\F56A4.10, Cele\R10D12.1, Cele\T28H11.8, Cele\vglu-2, Cele\M162.5, Cele\H11E01.2, Cele\T01H3.3, Cele\F44E7.7, Cele\Y4C6B.4, Cele\T27D12.1, Cele\T22F3.10, Cele\cima-1, Cele\K08C7.1, Cele\T22F3.7, Cele\C35A5.3, Cele\T19D12.10, Cele\F59A1.13, Cele\slc-17.9, Cele\Y19D10A.8, Cele\C39E9.7, Cele\D1046.4, Cele\Y51B9A.6, Cele\slc-17.8, Cele\W04C9.6, Cele\Y19D10A.4, Cele\K11G9.5, Cele\Y4C6B.3, Cele\M117.1, Cele\slc-17.1, Cele\T22F3.8" Xtro\slc17a7 "Mmus\Slc17a2, Mmus\Slc17a3, Mmus\Slc17a7, Mmus\Slc17a6, Mmus\Slc17a1, Mmus\Slc17a8, Mmus\Slc17a5, Mmus\Slc17a4" "Hsap\SLC17A8, Hsap\SLC17A1, Hsap\SLC17A7, Hsap\SLC17A2, Hsap\SLC17A6, Hsap\SLC17A3, Hsap\SLC17A4, Hsap\SLC17A5" "viable,lethal,recessive" FBgn0036188 CG7339 - http://flybase.org/reports/FBgn0036188 protein_coding_gene RNA polymerase III activity ; GO:0001056 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000295357 neurogenesis ; GO:0022008 | inferred from mutant phenotype transcription initiation from RNA polymerase III promoter ; GO:0006384 | inferred from biological aspect of ancestor with PANTHER:PTN000295357 DNA-directed RNA polymerase III complex ; GO:0005666 | inferred from biological aspect of ancestor with PANTHER:PTN000295357 "CG7339, lincRNA.S4825" "IPR005576:RNA polymerase Rpb7, N-terminal, IPR013238:RNA polymerase III, subunit Rpc25, IPR012340:Nucleic acid-binding, OB-fold" CG7339 27-Aug-18 DroID_v2018_08 Drer\polr3h Scer\RPC25 Cele\rpc-25 Xtro\polr3h Mmus\Polr3h Hsap\POLR3H "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0051866 Ada1-2 transcriptional Adaptor 1-2 http://flybase.org/reports/FBgn0051866 protein_coding_gene transcription coactivator activity ; GO:0003713 | inferred from biological aspect of ancestor with PANTHER:PTN001083423 histone acetyltransferase activity ; GO:0004402 | contributes_to inferred from direct assay transcription coactivator activity ; GO:0003713 | inferred from sequence or structural similarity with SGD:S000006175 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001083423 histone acetylation ; GO:0016573 | inferred from sequence or structural similarity with SGD:S000006175 histone H3 acetylation ; GO:0043966 | inferred from direct assay transcription from RNA polymerase II promoter ; GO:0006366 | inferred from sequence or structural similarity with SGD:S000006175 SAGA complex ; GO:0000124 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "Ada1-2, CG31866, Ada1, ada1-2" IPR024738:Transcriptional coactivator Hfi1/Transcriptional adapter 1 CG31866 27-Aug-18 DroID_v2018_08 Drer\tada1 Scer\HFI1 - Xtro\tada1 Mmus\Tada1 Hsap\TADA1 FBgn0041236 Gr59d Gustatory receptor 59d http://flybase.org/reports/FBgn0041236 protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 taste receptor activity ; GO:0008527 | inferred from sequence or structural similarity taste receptor activity ; GO:0008527 | non-traceable author statement sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of taste ; GO:0050909 | non-traceable author statement sensory perception of taste ; GO:0050909 | inferred from sequence or structural similarity sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 integral component of membrane ; GO:0016021 | non-traceable author statement axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 "CG30330, Gr59D1, 59D1, 59D.1, GR59D.1, CG13543, Gr59d, GR59d" IPR013604:7TM chemoreceptor CG30330 27-Aug-18 DroID_v2018_08 - - "Cele\gur-3, Cele\lite-1" - - - viable FBgn0032800 CG10137 - http://flybase.org/reports/FBgn0032800 protein_coding_gene - - - CG10137 IPR008979:Galactose-binding domain-like CG10137 27-Aug-18 DroID_v2018_08 "Drer\ace, Drer\ace2, Drer\cep104" - "Cele\T06D8.2, Cele\C40H1.3, Cele\F28C6.9, Cele\C06A8.8" "Xtro\ace2, Xtro\cep104, Xtro\ace" "Mmus\Ace, Mmus\Ace3, Mmus\Cep104, Mmus\Ace2" "Hsap\ACE2, Hsap\ACE, Hsap\CEP104" viable FBgn0013696 mt:tRNA:Ile-GAT mitochondrial transfer RNA:Isoleucine-GAT http://flybase.org/reports/FBgn0013696 FBgn0002867 tRNA_gene - - - "CR34060, tRNA[Ile], mtdbD00006292, mt:tRNA:Ile-GAT, mt:tRNA:I, mt:tRNA[Ile]" - CR34060 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039893 CG13301 - http://flybase.org/reports/FBgn0039893 protein_coding_gene - - - CG13301 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262882 CG43237 - http://flybase.org/reports/FBgn0262882 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43237, lincRNA.333" - CG43237 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0020806 ms(2)C32 ms(2)C32 http://flybase.org/reports/FBgn0020806 - gene - - - "2-C32, ms(2)C32" - - 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,recessive,chemical sensitive" FBgn0266637 asRNA:CR45144 - http://flybase.org/reports/FBgn0266637 non_protein_coding_gene - - - CR45144 - CR45144 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0010948 l(3)10621 lethal (3) 10621 http://flybase.org/reports/FBgn0010948 - gene - - - l(3)10621 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0005502 slf schlaff http://flybase.org/reports/FBgn0005502 "FBgn0001912, FBgn0003422" gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "l(2)25Aa, slf" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "embryonic/first instar larval cuticle,cephalopharyngeal skeleton,embryo,posterior,anterior" FBgn0043899 gsb::Mmus\Pax3 Pax3 http://flybase.org/reports/FBgn0043899 engineered_fusion_gene - - - gsb::Mmus\Pax3 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0067072 Mns Microtubule nucleation suppressor http://flybase.org/reports/FBgn0067072 gene - - - "MINUS, Minus, Mns" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031145 Ntf-2 Nuclear transport factor-2 http://flybase.org/reports/FBgn0031145 protein_coding_gene - transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR002075 positive regulation of antimicrobial peptide biosynthetic process ; GO:0002807 | inferred from mutant phenotype intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR002075 "DNTF-2, NTF-2, ntf2, Dntf-2, Dntf2, CG1740, dmNTF2, l(1)G0086, l(1)G0125, l(1)G0428, l(1)G0337, BcDNA:GM08921, Ntf-2, ntf-2, Ntf2" "IPR018222:Nuclear transport factor 2, eukaryote, IPR002075:Nuclear transport factor 2, IPR032710:NTF2-like domain" CG1740 27-Aug-18 DroID_v2018_08 "Drer\nutf2, Drer\nutf2l" Scer\NTF2 Cele\ran-4 Xtro\nutf2 "Mmus\Nutf2-ps2, Mmus\Nutf2" Hsap\NUTF2 " adult stage | male , adult stage | female " testis

"lethal,female,lethal - all die before end of larval stage,some die during larval stage,female fertile,viable,male,male fertile,visible,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,some die during third instar larval stage,partially lethal - majority die,some die during pupal stage,female sterile" "eye,mesothoracic tergum" FBgn0014966 gypsy\pol gypsy\polymerase http://flybase.org/reports/FBgn0014966 - transposable_element_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR012337 DNA integration ; GO:0015074 | inferred from electronic annotation with InterPro:IPR001584 - "DmeGypV int, ORF2, int, gypsy\pol, pol, RTase, RT" "IPR021109:Aspartic peptidase domain, IPR000477:Reverse transcriptase domain, IPR001584:Integrase, catalytic core, IPR012337:Ribonuclease H-like domain" - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032723 ssp3 short spindle 3 http://flybase.org/reports/FBgn0032723 protein_coding_gene - - spindle ; GO:0005819 | colocalizes_with inferred from direct assay "CG10666, ssp3, CG18397, Ssp3" "IPR032446:S phase cyclin A-associated protein in the endoplasmic reticulum, N-terminal" CG18397 27-Aug-18 DroID_v2018_08 Drer\scaper - Cele\Y6B3B.4 Xtro\scaper Mmus\Scaper Hsap\SCAPER "viable,fertile" FBgn0067055 Q9 Q9 http://flybase.org/reports/FBgn0067055 gene - - - Q9 - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,lethal,viable" chaeta FBgn0036987 CG5274 - http://flybase.org/reports/FBgn0036987 protein_coding_gene - - - CG5274 IPR027844:Protein of unknown function DUF4507 CG5274 27-Aug-18 DroID_v2018_08 Drer\zgc:56409 - Cele\Y56A3A.31 Xtro\c7orf26 Mmus\E130309D02Rik Hsap\C7orf26 "viable,fertile" DRSC11774 I 1.6241633 -0.55302344 0.020185487 0.360656914 0.208308987 0.300474956 FBgn0044123 E(rst)B50 E(rst)B50 http://flybase.org/reports/FBgn0044123 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "B50, E(rst)B50" - - 27-Aug-18 DroID_v2018_08 - - - - - - viable "eye,cone cell,primary pigment cell,secondary pigment cell,ectopic,tertiary pigment cell,interommatidial bristle" FBgn0028025 l(3)S103603 lethal (3) S103603 http://flybase.org/reports/FBgn0028025 gene - - - "1036/03, l(3)S103603" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0041839 E(Sev-CycE)G66 E(Sev-CycE)G66 http://flybase.org/reports/FBgn0041839 gene - - - E(Sev-CycE)G66 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0267091 asRNA:CR45535 - http://flybase.org/reports/FBgn0267091 non_protein_coding_gene - - - CR45535 - CR45535 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0014376 ptz pitzi http://flybase.org/reports/FBgn0014376 - gene - - - ptz - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260032 siren2 siren 2 http://flybase.org/reports/FBgn0260032 gene - - - siren2 - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,somatic clone" "wing,somatic clone" FBgn0024666 l(2)k05510 lethal (2) k05510 http://flybase.org/reports/FBgn0024666 - gene - - - "55/10, l(2)k05510" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" imaginal disc FBgn0003497 Sq Squat http://flybase.org/reports/FBgn0003497 - gene - - - Sq - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" "leg,head,adult thorax" FBgn0031092 CG9577 - http://flybase.org/reports/FBgn0031092 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR001753 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR001753 fatty acid beta-oxidation ; GO:0006635 | non-traceable author statement peroxisome ; GO:0005777 | inferred from sequence model lipid particle ; GO:0005811 | inferred from direct assay CG9577 "IPR001753:Crotonase superfamily, IPR014748:Crontonase, C-terminal, IPR029045:ClpP/crotonase-like domain" CG9577 27-Aug-18 DroID_v2018_08 Drer\ech1 "Scer\DCI1, Scer\ECI1" "Cele\Y25C1A.13, Cele\F58A6.1" Xtro\ech1 Mmus\Ech1 Hsap\ECH1 viable FBgn0263094 CG43362 - http://flybase.org/reports/FBgn0263094 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43362 - CG43362 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0066357 l(2)23CDg lethal (2) 23CDg http://flybase.org/reports/FBgn0066357 gene - - - l(2)23CDg - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035073 CG16896 - http://flybase.org/reports/FBgn0035073 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with Evi5 regulation of GTPase activity ; GO:0043087 | inferred from sequence or structural similarity with Evi5 centrosome ; GO:0005813 | inferred from biological aspect of ancestor with PANTHER:PTN001068643 CG16896 "IPR015943:WD40/YVTN repeat-like-containing domain, IPR000195:Rab-GTPase-TBC domain" CG16896 27-Aug-18 DroID_v2018_08 Drer\tbc1d31 - - Xtro\tbc1d31 Mmus\Tbc1d31 Hsap\TBC1D31 viable FBgn0013657 ms(2)neo2 ms(2)neo2 http://flybase.org/reports/FBgn0013657 - gene - - - ms(2)neo2 - - 27-Aug-18 DroID_v2018_08 - - - - - - male sterile FBgn0260740 Grip98 - http://flybase.org/reports/FBgn0260740 protein_coding_gene - - - "Grip98, Dgrip98, GCP3" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0086904 Nacalpha Nascent polypeptide associated complex protein alpha subunit http://flybase.org/reports/FBgn0086904 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9U9Q7 neurogenesis ; GO:0022008 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype - "aic, alphaNAC, alpha-NAC, NAC, l(2)04329, CG8759, Nacalpha, NACalpha" "IPR002715:Nascent polypeptide-associated complex NAC domain, IPR016641:Nascent polypeptide-associated complex subunit alpha" CG8759 27-Aug-18 DroID_v2018_08 "Drer\naca, Drer\nacad" Scer\EGD2 Cele\icd-2 "Xtro\naca, Xtro\naca.2" "Mmus\Naca, Mmus\Nacad" "Hsap\NACA, Hsap\NACA2, Hsap\NACAD" FBgn0034204 CG10953 - http://flybase.org/reports/FBgn0034204 protein_coding_gene - - - "CG10953, CG10953-PA" IPR004011:GYR motif CG10953 27-Aug-18 DroID_v2018_08 - - - - Mmus\Sprr3 - "visible,partially lethal - majority die,some die during pupal stage,viable" "trichogen cell,mesothoracic tergum" FBgn0259238 CG42336 - http://flybase.org/reports/FBgn0259238 protein_coding_gene - - - "CG42336, CG13210, BcDNA:AT13707, CG13211" - CG42336 27-Aug-18 DroID_v2018_08 - - Cele\C48B6.10 - - - FBgn0030327 FucT6 "alpha1,6-fucosyltransferase" http://flybase.org/reports/FBgn0030327 protein_coding_gene alpha-(1->6)-fucosyltransferase activity ; GO:0046921 | inferred from direct assay glycoprotein 6-alpha-L-fucosyltransferase activity ; GO:0008424 | inferred from sequence or structural similarity with UniProtKB:Q9BYC5 protein glycosylation in Golgi ; GO:0033578 | inferred from electronic annotation with InterPro:IPR015827 protein N-linked glycosylation ; GO:0006487 | inferred from biological aspect of ancestor with PANTHER:PTN000992822 N-glycan fucosylation ; GO:0036071 | inferred from biological aspect of ancestor with PANTHER:PTN000992822 GDP-L-fucose metabolic process ; GO:0046368 | inferred from sequence or structural similarity with UniProtKB:Q9BYC5 protein N-linked glycosylation via asparagine ; GO:0018279 | inferred from sequence or structural similarity with UniProtKB:Q9BYC5 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR015827 Golgi cisterna membrane ; GO:0032580 | inferred from electronic annotation with InterPro:IPR015827 "Fuc-TVIII, CG2448, CK00490, BEST:CK00490, FucT6, Dm alpha1,6-FucT, dalpha6Fut" "IPR001452:SH3 domain, IPR015827:Alpha-(1,6)-fucosyltransferase, eukaryotic type, IPR027350:Glycosyltransferase family 23 (GT23) domain" CG2448 27-Aug-18 DroID_v2018_08 "Drer\fut8a, Drer\fut8b" - Cele\fut-8 Xtro\fut8 Mmus\Fut8 Hsap\FUT8 "viable,fertile,immune response defective" FBgn0265694 lncRNA:CR44501 - http://flybase.org/reports/FBgn0265694 non_protein_coding_gene - - - "lincRNA.962, CR44501" - CR44501 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0281841 T:cic cic fragment http://flybase.org/reports/FBgn0281841 engineered_tag - - - T:cic - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004850 Su(var)204 Suppressor of variegation 204 http://flybase.org/reports/FBgn0004850 - gene - - - "Su(var)204, 204" - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,suppressor of variegation,dominant,non-suppressor of variegation" FBgn0011849 tRNA:Glu-TTC-1-5 transfer RNA:Glutamic acid-TTC 1-5 http://flybase.org/reports/FBgn0011849 "FBgn0003771, FBgn0011846, FBgn0050455, FBgn0060240" tRNA_gene GAA codon-amino acid adaptor activity ; GO:0033459 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033459 cytosol ; GO:0005829 | inferred by curator from GO:0033459 "CR30455, glu-tRNA-4, AE002787.trna5-GluTTC, tRNA:E4, tRNA:E:TTC:AE002787-b, tRNA:glu4:56Fb, tRNA:Glu, chr2R.trna63-GluTTC, tRNA:Glu-TTC-1-5, tRNA:E4:56Fb, tRNA-Glu-TTC-1-5, GAA" - CR30455 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033540 Elp2 Elongator complex protein 2 http://flybase.org/reports/FBgn0033540 protein_coding_gene microtubule binding ; GO:0008017 | inferred from biological aspect of ancestor with PANTHER:PTN000752735 endopeptidase activator activity ; GO:0061133 | inferred from sequence or structural similarity with UniProtKB:Q16186 transcription elongation from RNA polymerase II promoter ; GO:0006368 | inferred from sequence or structural similarity with UniProtKB:Q16186 proteasome assembly ; GO:0043248 | inferred from sequence or structural similarity with UniProtKB:Q16186 cell cortex ; GO:0005938 | inferred from biological aspect of ancestor with PANTHER:PTN000752735 microtubule associated complex ; GO:0005875 | inferred from biological aspect of ancestor with PANTHER:PTN000752735 microtubule ; GO:0005874 | inferred from biological aspect of ancestor with PANTHER:PTN000752735 kinetochore ; GO:0000776 | inferred from biological aspect of ancestor with PANTHER:PTN000752735 centrosome ; GO:0005813 | inferred from biological aspect of ancestor with PANTHER:PTN000752735 proteasome complex ; GO:0000502 | inferred from sequence or structural similarity with UniProtKB:Q16186 "CG1187, CG11887, Stip, elp-2, D-elp2, Elp2, StIP" "IPR001680:WD40 repeat, IPR019775:WD40 repeat, conserved site, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG11887 27-Aug-18 DroID_v2018_08 "Drer\elp2, Drer\nwd1" Scer\ELP2 Cele\elpc-2 Xtro\elp2 Mmus\Elp2 Hsap\ELP2 "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0029039 l(2)G56 lethal (2) G56 http://flybase.org/reports/FBgn0029039 gene - - - "G56, l(2)G56" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0035407 Asciz ASCIZ zinc finger protein http://flybase.org/reports/FBgn0035407 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype regulation of mitotic nuclear division ; GO:0007088 | inferred from mutant phenotype metamorphosis ; GO:0007552 | inferred from mutant phenotype polytene chromosome interband ; GO:0005705 | inferred from direct assay spindle matrix ; GO:1990047 | inferred from direct assay polytene chromosome puff ; GO:0005703 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "Asciz, dASCIZ, CG14962, CC15, Digitor" IPR013087:Zinc finger C2H2-type CG14962 27-Aug-18 DroID_v2018_08 "Drer\znf142, Drer\im:7147486, Drer\atmin" Scer\RME1 "Cele\zfp-2, Cele\C34H4.5, Cele\pag-3" Xtro\atmin "Mmus\Zbtb41, Mmus\Atmin, Mmus\Zfp142, Mmus\Zfp574" "Hsap\ZBTB41, Hsap\ZNF142, Hsap\ATMIN, Hsap\IKZF5, Hsap\ZNF574" "visible,mitotic cell cycle defective,increased cell death,lethal - all die during first instar larval stage,viable" "wing,posterior compartment,wing disc,somatic clone" FBgn0005118 l(1)FMb lethal (1) FMb http://flybase.org/reports/FBgn0005118 - gene - - - l(1)FMb - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0065938 l(2)SH0120 lethal (2) SH0120 http://flybase.org/reports/FBgn0065938 gene - - - "l(2)SH0120, l(2)SH2 0120" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0036778 Cyp312a1 Cyp312a1 http://flybase.org/reports/FBgn0036778 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002403 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002403 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002403 monooxygenase activity ; GO:0004497 | inferred from electronic annotation with InterPro:IPR002403" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002403" - "312a1, CG5137, Cyp312a1, P450 IV" "IPR001128:Cytochrome P450, IPR002403:Cytochrome P450, E-class, group IV" CG5137 27-Aug-18 DroID_v2018_08 "Drer\cyp1c1, Drer\cyp4t8, Drer\cyp26c1, Drer\cyp46a1.3, Drer\LOC100329425, Drer\cyp46a1.4, Drer\cyp4f3, Drer\cyp4v8, Drer\cyp4v7, Drer\cyp19a1a, Drer\cyp46a1.2, Drer\cyp1b1, Drer\cyp21a2, Drer\cyp26a1, Drer\cyp26b1, Drer\cyp1d1, Drer\cyp19a1b, Drer\cyp46a1.1, Drer\cyp20a1" "Scer\ERG11, Scer\ERG5, Scer\DIT2" "Cele\cyp-37A1, Cele\cyp-32A1, Cele\cyp-29A4, Cele\cyp-37B1, Cele\cyp-29A2, Cele\cyp-42A1, Cele\cyp-29A3, Cele\cyp-32B1, Cele\cyp-31A2, Cele\cyp-31A5, Cele\cyp-31A3" "Xtro\cyp26c1, Xtro\cyp1a1, Xtro\cyp4f2, Xtro\cyp20a1, Xtro\cyp4b1.2, Xtro\mgc108213, Xtro\LOC100488227, Xtro\cyp4f22, Xtro\cyp19a1, Xtro\cyp4v2, Xtro\LOC100487918, Xtro\cyp26a1, Xtro\cyp4b1, Xtro\cyp26b1" "Mmus\Cyp26c1, Mmus\Cyp51, Mmus\Cyp4b1, Mmus\Cyp20a1, Mmus\Cyp4a12a, Mmus\Cyp4f15, Mmus\Cyp4a29, Mmus\Cyp4f13, Mmus\Cyp4f17, Mmus\Cyp4a10, Mmus\Cyp4a30b, Mmus\Cyp4f14, Mmus\Cyp46a1, Mmus\Cyp4a12b, Mmus\Cyp4a31, Mmus\Cyp26a1, Mmus\Cyp4a14, Mmus\Cyp4f37, Mmus\Cyp4f39, Mmus\Cyp4v3, Mmus\Cyp4x1, Mmus\Cyp26b1, Mmus\Cyp4a32, Mmus\Cyp19a1, Mmus\Cyp4f18, Mmus\Cyp4f16, Mmus\Cyp4f40" "Hsap\CYP20A1, Hsap\CYP46A1, Hsap\CYP4F2, Hsap\CYP4Z1, Hsap\CYP4X1, Hsap\CYP4A11, Hsap\CYP4A22, Hsap\CYP4F8, Hsap\CYP51A1, Hsap\CYP19A1, Hsap\CYP4V2, Hsap\CYP4F11, Hsap\CYP26B1, Hsap\CYP26C1, Hsap\CYP4F22, Hsap\CYP4F12, Hsap\CYP26A1, Hsap\CYP4B1, Hsap\CYP4F3" viable FBgn0005293 mei-2245 meiotic 2245 http://flybase.org/reports/FBgn0005293 - gene - - - "2245, mei-2245" - - 27-Aug-18 DroID_v2018_08 - - - - - - "meiotic cell cycle defective,recessive" meiosis & nuclear chromosome FBgn0040909 CG12686 - http://flybase.org/reports/FBgn0040909 protein_coding_gene - - - CG12686 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039500 CG5984 - http://flybase.org/reports/FBgn0039500 protein_coding_gene actin binding ; GO:0003779 | inferred from sequence or structural similarity - - CG5984 "IPR001298:Filamin/ABP280 repeat, IPR013783:Immunoglobulin-like fold, IPR014756:Immunoglobulin E-set, IPR017868:Filamin/ABP280 repeat-like" CG5984 27-Aug-18 DroID_v2018_08 "Drer\flna, Drer\flnb, Drer\flnca, Drer\LOC100534866, Drer\flncb, Drer\flnbl" - Cele\fln-1 "Xtro\flnb, Xtro\flnc, Xtro\flna" "Mmus\Flnc, Mmus\Flna, Mmus\Flnb" "Hsap\FLNC, Hsap\FLNB, Hsap\FLNA" FBgn0053234 CG33234 - http://flybase.org/reports/FBgn0053234 protein_coding_gene substrate-specific transmembrane transporter activity ; GO:0022891 | inferred from biological aspect of ancestor with PANTHER:PTN000756324 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000628500 "CG12036, CG33234" "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG33234 27-Aug-18 DroID_v2018_08 "Drer\slc22a7b.1, Drer\sv2ba, Drer\sv2a, Drer\slc22a7b.3, Drer\zmp:0000001102, Drer\slc22a13, Drer\slc22a21, Drer\LOC100334012, Drer\sv2bb, Drer\sv2c, Drer\slc22a5, Drer\LOC101884074, Drer\sv2, Drer\zgc:175176, Drer\slc22a6l, Drer\oatx, Drer\slc22a7b.2" "Scer\DTR1, Scer\YHK8, Scer\QDR1, Scer\AQR1, Scer\QDR3, Scer\TPO3, Scer\TPO1, Scer\FLR1, Scer\TPO2, Scer\GIT1, Scer\QDR2" "Cele\T12B3.2, Cele\F23F12.13, Cele\K11D9.3, Cele\F23F12.3, Cele\C44C10.3, Cele\svop-1" "Xtro\slc22a6, Xtro\sv2b" "Mmus\Slc22a20, Mmus\Slc22a28, Mmus\Slc22a14, Mmus\Slc22a22, Mmus\Slc22a26, Mmus\Sv2b, Mmus\Slc22a4, Mmus\Slc22a19, Mmus\Slc22a27, Mmus\Slc22a8, Mmus\Slc22a29, Mmus\Svop, Mmus\Slc22a16, Mmus\Slc22a6, Mmus\Slc22a2, Mmus\Slc22a23, Mmus\Slc22a30, Mmus\Sv2c, Mmus\Slc22a7, Mmus\Sv2a" "Hsap\SLC22A25, Hsap\SV2B, Hsap\SVOP, Hsap\SV2C, Hsap\SLC22A1, Hsap\SV2A, Hsap\SLC22A12, Hsap\SLC22A7, Hsap\SLC22A10, Hsap\SLC22A9, Hsap\SLC22A8, Hsap\SLC22A24, Hsap\SLC22A23, Hsap\SLC22A11, Hsap\SLC22A6, Hsap\SLC22A2" FBgn0085271 CG34242 - http://flybase.org/reports/FBgn0085271 protein_coding_gene - - - CG34242 IPR027917:Protein of unknown function DUF4538 CG34242 27-Aug-18 DroID_v2018_08 Drer\smim20 - - - Mmus\Smim20 Hsap\SMIM20 FBgn0000846 fs(1)M33 female sterile (1) M33 http://flybase.org/reports/FBgn0000846 - gene - - - fs(1)M33 - - 27-Aug-18 DroID_v2018_08 - - - - - - female sterile chorion FBgn0061027 l(3)S024706b lethal (3) S024706b http://flybase.org/reports/FBgn0061027 gene - - - "0247/06, l(3)S024706b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0266175 pre-mod(mdg4)-P - http://flybase.org/reports/FBgn0266175 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "pre-mod(mdg4)-P, CG44881" "IPR007588:Zinc finger, FLYWCH-type" CG44881 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0028693 Rpn12 Regulatory particle non-ATPase 12 http://flybase.org/reports/FBgn0028693 protein_coding_gene molecular_function ; GO:0003674 | no biological data available neurogenesis ; GO:0022008 | inferred from mutant phenotype ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from sequence or structural similarity with SGD:S000001948 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred by curator from GO:0000502 proteasome assembly ; GO:0043248 | inferred from biological aspect of ancestor with PANTHER:PTN000273181 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from mutant phenotype "proteasome regulatory particle ; GO:0005838 | inferred from sequence or structural similarity with HGNC:9566 inferred from direct assay nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000273181 proteasome complex ; GO:0000502 | inferred from direct assay proteasome regulatory particle, lid subcomplex ; GO:0008541 | inferred from biological aspect of ancestor with PANTHER:PTN000273181 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000273181 proteasome regulatory particle, lid subcomplex ; GO:0008541 | inferred from sequence or structural similarity with SGD:S000001948" "dRpn12, p30, CG4157, Rpn12, S14" "IPR006746:26S proteasome non-ATPase regulatory subunit Rpn12, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR033464:CSN8/PSMD8/EIF3K" CG4157 27-Aug-18 DroID_v2018_08 Drer\psmd8 Scer\RPN12 Cele\rpn-12 Xtro\psmd8 Mmus\Psmd8 Hsap\PSMD8 "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC11275 IEK -2.898831702 -3.190066818 -2.817372184 -1.933076306 1.385172297 -2.642958187 FBgn0011045 l(1)Stark-d lethal (1) of Stark d http://flybase.org/reports/FBgn0011045 FBgn0010212 gene - - - "l(1)Stark-d, l(1)Sd" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0029955 CG15478 - http://flybase.org/reports/FBgn0029955 protein_coding_gene - - - CG15478 IPR015943:WD40/YVTN repeat-like-containing domain CG15478 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "heart primordium,chaeta,supernumerary" FBgn0051648 CG31648 - http://flybase.org/reports/FBgn0051648 protein_coding_gene copper ion binding ; GO:0005507 | inferred from sequence or structural similarity with SGD:S000006053 aerobic respiration ; GO:0009060 | inferred from sequence or structural similarity with SGD:S000006053 respiratory chain complex IV assembly ; GO:0008535 | inferred from sequence or structural similarity with UniProtKB:Q9Y6N1 - "CG6922, CG31648, COXZ" "IPR007533:Cytochrome c oxidase assembly protein CtaG/Cox11, IPR023471:Cytochrome c oxidase assembly protein CtaG/Cox11, domain" CG31648 27-Aug-18 DroID_v2018_08 Drer\cox11 Scer\COX11 Cele\cox-11 Xtro\cox11 Mmus\Cox11 Hsap\COX11 "viable,visible" trichogen cell FBgn0067040 W10 W10 http://flybase.org/reports/FBgn0067040 gene - - - W10 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,viable" FBgn0023096 btv beethoven http://flybase.org/reports/FBgn0023096 FBgn0032657 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011704 ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity ATP-dependent microtubule motor activity, minus-end-directed ; GO:0008569 | inferred from sequence or structural similarity with UniProtKB:A8JDH8" "male courtship behavior ; GO:0008049 | inferred from mutant phenotype male courtship behavior, veined wing generated song production ; GO:0045433 | inferred from mutant phenotype adult walking behavior ; GO:0007628 | inferred from mutant phenotype intraciliary retrograde transport ; GO:0035721 | inferred from mutant phenotype sensory perception of sound ; GO:0007605 | inferred from mutant phenotype auditory behavior ; GO:0031223 | inferred from mutant phenotype microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity" cytoplasmic dynein complex ; GO:0005868 | inferred from sequence or structural similarity axoneme ; GO:0005930 | inferred from mutant phenotype cytoplasmic dynein complex ; GO:0005868 | inferred from sequence or structural similarity with UniProtKB:P36022 "CG15148, DHC, Dhc36D, DHC36D, btv, DHC2" "IPR004273:Dynein heavy chain domain, IPR011704:ATPase, dynein-related, AAA domain, IPR013594:Dynein heavy chain, domain-1, IPR013602:Dynein heavy chain, domain-2, IPR003593:AAA+ ATPase domain, IPR024317:Dynein heavy chain, P-loop containing D4 domain, IPR024743:Dynein heavy chain, coiled coil stalk, IPR026815:Cytoplasmic dynein 2 heavy chain 1, IPR026983:Dynein heavy chain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG15148 27-Aug-18 DroID_v2018_08 "Drer\dnah12, Drer\dnah7, Drer\dnah9l, Drer\si:dkeyp-86b9.1, Drer\wu:fj30b09, Drer\dnah3, Drer\dnah2, Drer\si:dkeyp-87a6.1, Drer\dnah1, Drer\dync1h1, Drer\dnah7l" Scer\DYN1 "Cele\che-3, Cele\dhc-1" "Xtro\dnah14, Xtro\dnah2, Xtro\dnah7" "Mmus\Dnah12, Mmus\Dnah8, Mmus\Dync1h1, Mmus\Dnah1, Mmus\Dnah5, Mmus\Dnah9, Mmus\Dnah6, Mmus\Dnah7a, Mmus\Dnah10, Mmus\Dnah3, Mmus\Dync2h1, Mmus\Dnah17, Mmus\Dnah7b, Mmus\Dnah7c, Mmus\Dnah2, Mmus\Dnah11, Mmus\Dnhd1" "Hsap\DNAH6, Hsap\DNAH8, Hsap\CCDC88B, Hsap\DNAH2, Hsap\DYNC1H1, Hsap\DNAH5, Hsap\DNAH9, Hsap\DNAH14, Hsap\DNHD1, Hsap\DNAH7, Hsap\DNAH12, Hsap\DNAH10, Hsap\DNAH1, Hsap\DNAH3, Hsap\DNAH17, Hsap\DNAH11, Hsap\DYNC2H1" "thermotaxis behavior defective,touch sensitivity defective,locomotor behavior defective,auditory perception defective,neuroanatomy defective,viable,smell perception defective,courtship behavior defective,male,male fertile,song defective,recessive,behavior defective" "abdominal lateral pentascolopidial chordotonal organ lch5 & scolopidium,arista,mechanosensory sensory organ,wing,adult antennal nerve" FBgn0265860 lncRNA:CR44649 - http://flybase.org/reports/FBgn0265860 non_protein_coding_gene - - - CR44649 - CR44649 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031184 CG14615 - http://flybase.org/reports/FBgn0031184 protein_coding_gene "transferase activity, transferring acyl groups other than amino-acyl groups ; GO:0016747 | inferred from electronic annotation with InterPro:IPR013653" - - CG14615 "IPR016181:Acyl-CoA N-acyltransferase, IPR013653:FR47-like" CG14615 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-76k16.5, Drer\si:ch73-106k19.2, Drer\si:dkey-76k16.6" - Cele\ZK185.3 - - Hsap\GLYATL3 viable FBgn0001018 fs(3)A9 female sterile (3) A9 http://flybase.org/reports/FBgn0001018 - gene - - - fs(3)A9 - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive" female reproductive system FBgn0005093 fs(2)OWc5 female sterile (2) OWc5 http://flybase.org/reports/FBgn0005093 - gene - - - fs(2)OWc5 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037726 CG9492 - http://flybase.org/reports/FBgn0037726 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011704 ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity ATP-dependent microtubule motor activity, minus-end-directed ; GO:0008569 | inferred from sequence or structural similarity with UniProtKB:A8JDH8" microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity cilium movement ; GO:0003341 | inferred from sequence or structural similarity with UniProtKB:A8JDH8 sensory perception of sound ; GO:0007605 | inferred from mutant phenotype outer dynein arm ; GO:0036157 | inferred from sequence or structural similarity with UniProtKB:Q8TE73 microtubule associated complex ; GO:0005875 | inferred from direct assay dynein complex ; GO:0030286 | inferred from sequence or structural similarity "CG9492, DHC3B" "IPR004273:Dynein heavy chain domain, IPR011704:ATPase, dynein-related, AAA domain, IPR013594:Dynein heavy chain, domain-1, IPR013602:Dynein heavy chain, domain-2, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR003593:AAA+ ATPase domain, IPR024317:Dynein heavy chain, P-loop containing D4 domain, IPR024743:Dynein heavy chain, coiled coil stalk, IPR026983:Dynein heavy chain" CG9492 27-Aug-18 DroID_v2018_08 "Drer\dnah2, Drer\dnah1, Drer\dnah3, Drer\si:dkeyp-86b9.1, Drer\dnah9l, Drer\dnah7, Drer\dync1h1, Drer\dnah7l, Drer\si:dkeyp-87a6.1, Drer\dnah12, Drer\wu:fj30b09, Drer\dnah5" Scer\DYN1 "Cele\che-3, Cele\dhc-1" "Xtro\dnah14, Xtro\dnah5, Xtro\dnah2, Xtro\dnah7" "Mmus\Dnah1, Mmus\Dnah5, Mmus\Dnah8, Mmus\Dnah11, Mmus\Dnah7b, Mmus\Dnah7a, Mmus\Dnah17, Mmus\Dnah6, Mmus\Dnah10, Mmus\Dnah9, Mmus\Dync2h1, Mmus\Dnhd1, Mmus\Dync1h1, Mmus\Dnah12, Mmus\Dnah3, Mmus\Dnah2" "Hsap\DNAH17, Hsap\DNAH9, Hsap\DNAH7, Hsap\CCDC88B, Hsap\DNHD1, Hsap\DNAH6, Hsap\DYNC2H1, Hsap\DNAH8, Hsap\DNAH12, Hsap\DNAH14, Hsap\DNAH3, Hsap\DNAH1, Hsap\DNAH10, Hsap\DNAH2, Hsap\DYNC1H1, Hsap\DNAH11, Hsap\DNAH5" "auditory perception defective,neurophysiology defective" FBgn0262563 CG43103 - http://flybase.org/reports/FBgn0262563 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43103, Dm_2R:55417" - CG43103 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0044101 E(rst)C532 E(rst)C532 http://flybase.org/reports/FBgn0044101 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "C532, E(rst)C532" - - 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0069427 JJF014 JJF014 http://flybase.org/reports/FBgn0069427 gene - - - JJF014 - - 27-Aug-18 DroID_v2018_08 - - - - - - stress response defective FBgn0029539 CG11663 - http://flybase.org/reports/FBgn0029539 protein_coding_gene - - - "BcDNA:AT05678, CG11663" IPR015943:WD40/YVTN repeat-like-containing domain CG11663 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0010179 tu(2)49k tu(2)49k http://flybase.org/reports/FBgn0010179 - gene - - - tu(2)49k - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,melanotic mass phenotype" melanotic mass FBgn0039675 ppk21 pickpocket 21 http://flybase.org/reports/FBgn0039675 protein_coding_gene sodium channel activity ; GO:0005272 | inferred from sequence or structural similarity with MGI:MGI:101782 sodium ion transport ; GO:0006814 | inferred from sequence or structural similarity with MGI:MGI:101782 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with MGI:MGI:101782 "PPK21, CG12048, ppk21, Ppk21" IPR001873:Epithelial sodium channel CG12048 27-Aug-18 DroID_v2018_08 "Drer\asic1a, Drer\asic4b, Drer\asic1c, Drer\asic1b, Drer\asic2, Drer\asic4a" - "Cele\mec-10, Cele\del-10, Cele\egas-3, Cele\delm-2, Cele\unc-105, Cele\del-1, Cele\delm-1, Cele\asic-1, Cele\del-7, Cele\mec-4, Cele\egas-1, Cele\flr-1, Cele\deg-1, Cele\acd-4, Cele\degt-1, Cele\egas-2, Cele\unc-8, Cele\egas-4, Cele\acd-1, Cele\asic-2, Cele\del-4" "Xtro\asic5, Xtro\scnn1b, Xtro\scnn1d, Xtro\asic4, Xtro\scnn1a, Xtro\scnn1g, Xtro\asic1" "Mmus\Asic5, Mmus\Asic3, Mmus\Asic4, Mmus\Scnn1a, Mmus\Scnn1g, Mmus\Asic1, Mmus\Asic2, Mmus\Scnn1b" "Hsap\SCNN1G, Hsap\SCNN1B, Hsap\ASIC3, Hsap\ASIC1, Hsap\ASIC5, Hsap\SCNN1D, Hsap\ASIC2, Hsap\SCNN1A, Hsap\ASIC4" viable FBgn0037935 CG6834 - http://flybase.org/reports/FBgn0037935 protein_coding_gene myosin binding ; GO:0017022 | inferred from physical interaction with Myo10A - - CG6834 "IPR015897:CHK kinase-like, IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain" CG6834 27-Aug-18 DroID_v2018_08 - - "Cele\H06H21.8, Cele\nhr-246, Cele\F20D6.5" - - - "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0002234 l(3)68Ba lethal (3) 68Ba http://flybase.org/reports/FBgn0002234 FBgn0002230 gene - - - "l(3)C141, A, l(3)A, l(3)68Ba" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0266493 s-108 - http://flybase.org/reports/FBgn0266493 gene - - - s-108 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037044 CG10585 - http://flybase.org/reports/FBgn0037044 protein_coding_gene - isoprenoid biosynthetic process ; GO:0008299 | inferred from electronic annotation with InterPro:IPR000092 - CG10585 "IPR008949:Isoprenoid synthase domain, IPR000092:Polyprenyl synthetase" CG10585 27-Aug-18 DroID_v2018_08 "Drer\pdss2, Drer\pdss1" Scer\COQ1 - "Xtro\pdss1, Xtro\pdss2" "Mmus\Pdss2, Mmus\Pdss1" "Hsap\PDSS2, Hsap\PDSS1" "viable,fertile,lethal,partially lethal - majority die,visible" "embryonic/larval hemocyte | third instar larval stage,mesothoracic tergum" FBgn0267173 lncRNA:CR45613 - http://flybase.org/reports/FBgn0267173 non_protein_coding_gene - - - CR45613 - CR45613 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0020594 anon-57Cc anon-57Cc http://flybase.org/reports/FBgn0020594 - gene - - - anon-57Cc - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0058402 CG40402 - http://flybase.org/reports/FBgn0058402 protein_coding_gene - - - CG40402 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0010319 Cdi11 Cyclin-dependent kinase interactor 11 http://flybase.org/reports/FBgn0010319 - gene - - - "CDI11, cdi11, Cdi11" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0044002 Su(rst)C352 Su(rst)C352 http://flybase.org/reports/FBgn0044002 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "C352, Su(rst)C352" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264407 FCG-J - http://flybase.org/reports/FBgn0264407 gene - - - "FCG-J, FC G-J" - - 27-Aug-18 DroID_v2018_08 - - - - - - "follicle cell,somatic clone" FBgn0085240 CG34211 - http://flybase.org/reports/FBgn0085240 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34211 - CG34211 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0070030 BG00080 BG00080 http://flybase.org/reports/FBgn0070030 gene - - - BG00080 - - 27-Aug-18 DroID_v2018_08 - - - - - - "stress response defective,long lived,female limited,starvation stress response defective,temperature response defective,gravitaxis defective,sleep defective" FBgn0085292 CG34263 - http://flybase.org/reports/FBgn0085292 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34263 IPR002350:Kazal domain CG34263 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0261739 EC4330 - http://flybase.org/reports/FBgn0261739 gene - - - EC4330 - - 27-Aug-18 DroID_v2018_08 - - - - - - female sterile FBgn0083965 CG34129 - http://flybase.org/reports/FBgn0083965 protein_coding_gene molecular_function ; GO:0003674 | no biological data available serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "CG6069, SPH192, CG34129" "IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan" CG34129 27-Aug-18 DroID_v2018_08 "Drer\tmprss13a, Drer\tmprss13b, Drer\LOC100331291" - Cele\svh-1 - "Mmus\Try5, Mmus\1810009J06Rik, Mmus\Tmprss11d, Mmus\Prss57, Mmus\Prss40, Mmus\Gzmk, Mmus\Tmprss11c, Mmus\Prss45, Mmus\Tmprss11b, Mmus\Prss39, Mmus\Tmprss11e" "Hsap\PRSS45, Hsap\PRSS57, Hsap\GZMK, Hsap\TMPRSS11E, Hsap\PRSS3, Hsap\TMPRSS11D, Hsap\TMPRSS11B" viable FBgn0035933 CG13309 - http://flybase.org/reports/FBgn0035933 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 molecular_function ; GO:0003674 | no biological data available chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 extracellular space ; GO:0005615 | inferred from sequence model "CT32604, CG13309" IPR002557:Chitin binding domain CG13309 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0020301 fs(3)100C fs(3)100C http://flybase.org/reports/FBgn0020301 - gene - - - "fs(100C), fs(3)100C" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030277 CG1394 - http://flybase.org/reports/FBgn0030277 protein_coding_gene - - - "bs30g07.y1, BEST:GH24085, anon-WO0140519.177, CG1394" - CG1394 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0004825 fs(2)ltoQE45 female sterile (2) ltoQE45 http://flybase.org/reports/FBgn0004825 - gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(2)ltoQE45 - - 27-Aug-18 DroID_v2018_08 - - - - - - female sterile FBgn0003710 tipE temperature-induced paralytic E http://flybase.org/reports/FBgn0003710 - protein_coding_gene voltage-gated sodium channel activity ; GO:0005248 | traceable author statement sodium channel regulator activity ; GO:0017080 | inferred from direct assay "cellular response to heat ; GO:0034605 | inferred from direct assay regulation of sodium ion transport ; GO:0002028 | inferred from direct assay sodium ion transport ; GO:0006814 | non-traceable author statement male courtship behavior, veined wing generated song production ; GO:0045433 | inferred from mutant phenotype" plasma membrane ; GO:0005886 | traceable author statement plasma membrane ; GO:0005886 | inferred from sequence or structural similarity inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from direct assay "TipE, tip-E, CG1232, tipE" IPR031578:Na+ channel auxiliary subunit TipE CG1232 27-Aug-18 DroID_v2018_08 - - - - - - " embryonic stage , adult stage " " embryonic peripheral nervous system

, leg

, antenna

, antenno-maxillary complex

, adult head

, central nervous system

" "wild-type,paralytic,heat sensitive,chemical resistant,courtship behavior defective,male,recessive,neuroanatomy defective,viable,visible,lethal" "neuromuscular junction & synapse,synapse | ectopic | heat sensitive,trichogen cell" FBgn0001516 l(1)10Fj lethal (1) 10Fj http://flybase.org/reports/FBgn0001516 - gene - - - l(1)10Fj - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,polyphasic,recessive,cell lethal,germline clone" FBgn0040334 Tsp3A Tetraspanin 3A http://flybase.org/reports/FBgn0040334 protein_coding_gene molecular_function ; GO:0003674 | no biological data available positive regulation of Notch signaling pathway ; GO:0045747 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "CG10742, BACR7C10.6, EG:BACR7C10.6, Dm.Tsp3A, Tsp3A, tsp3A" "IPR018499:Tetraspanin/Peripherin, IPR000301:Tetraspanin, IPR008952:Tetraspanin, EC2 domain" CG10742 27-Aug-18 DroID_v2018_08 "Drer\tspan15, Drer\tspan5b, Drer\tspan14, Drer\zgc:110329, Drer\tspan33b, Drer\zgc:113223, Drer\tspan5a, Drer\LOC799194, Drer\tspan33a" - Cele\tsp-12 "Xtro\tspan33, Xtro\tspan15, Xtro\tspan5, Xtro\tspan17, Xtro\tspan14" "Mmus\Tspan17, Mmus\Tspan10, Mmus\Tspan5, Mmus\Tspan15, Mmus\Tspan14, Mmus\Rom1, Mmus\Tspan33" "Hsap\TSPAN14, Hsap\TSPAN33, Hsap\TSPAN15, Hsap\TSPAN17, Hsap\TSPAN10, Hsap\TSPAN5, Hsap\ROM1" "viable,fertile" "sensory mother cell,somatic clone,supernumerary" FBgn0030415 CG15726 - http://flybase.org/reports/FBgn0030415 protein_coding_gene - - - CG15726 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263329 lncRNA:CR43410 - http://flybase.org/reports/FBgn0263329 non_protein_coding_gene - - - CR43410 - CR43410 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260590 2L3081 - http://flybase.org/reports/FBgn0260590 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L3081 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0014903 CG14630 - http://flybase.org/reports/FBgn0014903 FBgn0029555 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR003819 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR003819 - "EG:BACR7A4.9, anon-1Eb, B, CG14630" "IPR003819:TauD/TfdA-like domain, IPR007175:RNAse P, Rpr2/Rpp21 subunit, IPR010376:Domain of unknown function DUF971" CG14630 27-Aug-18 DroID_v2018_08 "Drer\tmlhe, Drer\bbox1" Scer\AIM17 "Cele\gbh-1, Cele\gbh-2" "Xtro\tmlhe, Xtro\bbox1" "Mmus\Tmlhe, Mmus\Bbox1" "Hsap\TMLHE, Hsap\BBOX1" DRSC18166 I 2.419458636 0.134205101 0.826608037 0.346478239 -0.77077799 0.093511441 FBgn0010213 Sod2 Superoxide dismutase 2 (Mn) http://flybase.org/reports/FBgn0010213 - protein_coding_gene "metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR001189, InterPro:IPR019831, InterPro:IPR019832, InterPro:IPR019833 antioxidant activity ; GO:0016209 | non-traceable author statement superoxide dismutase activity ; GO:0004784 | inferred from sequence or structural similarity with UniProtKB:P04179" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001189, InterPro:IPR019831, InterPro:IPR019832, InterPro:IPR019833 heart morphogenesis ; GO:0003007 | inferred from mutant phenotype removal of superoxide radicals ; GO:0019430 | inferred from sequence or structural similarity with UniProtKB:P04179 regulation of hemocyte proliferation ; GO:0035206 | inferred from mutant phenotype regulation of mitophagy ; GO:1903146 | inferred from genetic interaction with park reactive oxygen species metabolic process ; GO:0072593 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | traceable author statement regulation of metabolic process ; GO:0019222 | inferred from mutant phenotype paracrine signaling ; GO:0038001 | inferred from mutant phenotype" mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:P04179 "Sod-2, MnSOD, Mn-SOD, Mn[2+]SOD, SOD2, CG8905, Mn SOD, mnSOD, SOD, SOD-2, Sod2, MnSODII, sod2, dSOD2, Mn-SOD2, mitSOD2, Mito SOD, dSod2" "IPR001189:Manganese/iron superoxide dismutase, IPR019831:Manganese/iron superoxide dismutase, N-terminal, IPR019832:Manganese/iron superoxide dismutase, C-terminal, IPR019833:Manganese/iron superoxide dismutase, binding site" CG8905 27-Aug-18 DroID_v2018_08 Drer\sod2 "Scer\SOD2, Scer\MRP1, Scer\RSM26" "Cele\sod-3, Cele\sod-2" Xtro\sod2 Mmus\Sod2 Hsap\SOD2 "short lived,tetracycline conditional,long lived,heat sensitive,viable,fertile,dominant,chemical sensitive,recessive,stress response defective,locomotor behavior defective,behavior defective,smell perception defective,gravitaxis defective,increased cell death,lethal,some die during immature adult stage,decreased cell number,conditional,oxidative stress response defective,bang sensitive,progressive,neuroanatomy defective" "adult heart,adult brain,lamellocyte,conditional,embryonic/larval motor neuron" DRSC07554 E -0.018967043 0.145473639 -1.958978767 0.477877685 0.162888548 0.129518469 FBgn0265914 asRNA:CR44703 - http://flybase.org/reports/FBgn0265914 non_protein_coding_gene - - - CR44703 - CR44703 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0028995 ponderosa ponderosa http://flybase.org/reports/FBgn0028995 gene molecular_function ; GO:0003674 | no biological data available dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available ponderosa - - 27-Aug-18 DroID_v2018_08 - - - - - - dendrite | dorsal | embryonic stage FBgn0001692 l(1)ESHS13 lethal (1) ESHS13 http://flybase.org/reports/FBgn0001692 - gene - - - l(1)ESHS13 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0004085 Ec3 Ecysone-induced RNA 3 http://flybase.org/reports/FBgn0004085 - gene - - - Ec3 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0043480 l(3)66EFf lethal (3) 66EFf http://flybase.org/reports/FBgn0043480 gene - - - l(3)66EFf - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0034183 SmydA-6 "SET and MYND domain containing, arthropod-specific, member 6" http://flybase.org/reports/FBgn0034183 protein_coding_gene histone deacetylase binding ; GO:0042826 | inferred from sequence or structural similarity with Smyd4-2 negative regulation of gene expression ; GO:0010629 | inferred from sequence or structural similarity with Smyd4-2 - "SmydA-6, CG9642" IPR001214:SET domain CG9642 27-Aug-18 DroID_v2018_08 "Drer\erlin2, Drer\smyd3, Drer\smyd4, Drer\erlin1, Drer\smyd2a, Drer\smyd2b, Drer\smyd1b, Drer\smyd1a" "Scer\SET5, Scer\SET6" "Cele\set-30, Cele\set-18, Cele\erl-1, Cele\set-10" "Xtro\smyd4, Xtro\erlin2, Xtro\erlin1, Xtro\smyd5, Xtro\smyd1" "Mmus\Smyd3, Mmus\Smyd2, Mmus\Smyd4, Mmus\Smyd1, Mmus\Zmynd15, Mmus\Erlin2, Mmus\Erlin1, Mmus\Smyd5" "Hsap\SMYD1, Hsap\SMYD3, Hsap\ERLIN1, Hsap\SMYD4, Hsap\SMYD2, Hsap\SMYD5, Hsap\ZMYND15" viable FBgn0043035 l(2)42Bi lethal (2) 42Bi http://flybase.org/reports/FBgn0043035 gene - - - l(2)42Bi - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0052512 CG32512 - http://flybase.org/reports/FBgn0052512 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG15447, CG1739, CG32512" IPR025423:Domain of unknown function DUF4149 CG32512 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-121a2.4, Drer\tmem205" Scer\YPR098C - Xtro\tmem205 Mmus\Tmem205 Hsap\TMEM205 "partially lethal - majority die,some die during pupal stage" FBgn0264857 lncRNA:iab8 iab-8 non-coding RNA http://flybase.org/reports/FBgn0264857 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "iab-8, iab-8 ncRNA, iab, msa, CG31270, mpa, CR43261, miR-iab-8, iab-8ncRNA" - CR43261 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,female sterile" FBgn0032233 dpr19 defective proboscis extension response 19 http://flybase.org/reports/FBgn0032233 protein_coding_gene molecular_function ; GO:0003674 | no biological data available synapse organization ; GO:0050808 | inferred from expression pattern sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with dpr1 integral component of plasma membrane ; GO:0005887 | inferred from sequence model "CG13140, Dpr-19, BcDNA:LP09705, dpr19, Dpr19" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR013106:Immunoglobulin V-set domain, IPR013783:Immunoglobulin-like fold" CG13140 27-Aug-18 DroID_v2018_08 "Drer\ush2a, Drer\ncam1b, Drer\LOC100333196, Drer\kirrel3a, Drer\igsf9a, Drer\sdk1a, Drer\sdk1b, Drer\si:ch211-264f5.6, Drer\lrit3b, Drer\kirrela, Drer\igsf9bb, Drer\LOC101885444, Drer\kirrel3b, Drer\dscama, Drer\si:dkey-65b12.12, Drer\paplna, Drer\itgb4, Drer\kirrel3l, Drer\lrit3a, Drer\lrit1b, Drer\kirrelb, Drer\si:ch1073-459j12.1, Drer\lrit1a" - Cele\zig-8 "Xtro\nfasc, Xtro\kirrel2, Xtro\igsf9b, Xtro\obsl1, Xtro\lrit3, Xtro\papln" "Mmus\Amica1, Mmus\Lrit1, Mmus\Lrit3, Mmus\Kirrel3, Mmus\Kirrel, Mmus\Ptprq, Mmus\Sdk1, Mmus\Kirrel2, Mmus\Papln, Mmus\Igsf9b" "Hsap\USH2A, Hsap\KIRREL3, Hsap\SDK1, Hsap\CADM3, Hsap\LRIT3, Hsap\KIRREL2, Hsap\CADM4, Hsap\KIRREL, Hsap\LRIT1, Hsap\CADM1, Hsap\PAPLN, Hsap\IGSF9B, Hsap\CADM2" viable FBgn0050154 CG30154 - http://flybase.org/reports/FBgn0050154 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG30154 - CG30154 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0039405 PIG-P Phosphatidylinositol glycan anchor biosynthesis class P http://flybase.org/reports/FBgn0039405 protein_coding_gene phosphatidylinositol N-acetylglucosaminyltransferase activity ; GO:0017176 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000497247 UDP-glycosyltransferase activity ; GO:0008194 | contributes_to inferred from sequence or structural similarity with SGD:S000002845 GPI anchor biosynthetic process ; GO:0006506 | inferred from sequence or structural similarity with SGD:S000002845 endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with SGD:S000002845 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex ; GO:0000506 | inferred from biological aspect of ancestor with PANTHER:PTN001094394 "BcDNA:GM30016, Dromel_CG14550_FBtr0084974_mORF, PIG-P, CG14550" IPR013717:PIG-P CG14550 27-Aug-18 DroID_v2018_08 "Drer\pigp, Drer\noa1" Scer\GPI19 Cele\Y48E1B.2 Xtro\pigp "Mmus\Noa1, Mmus\Gm6880, Mmus\Lage3, Mmus\Pigp, Mmus\Gm6890, Mmus\Ctag2" "Hsap\CTAG2, Hsap\LAGE3, Hsap\NOA1, Hsap\PIGP" viable FBgn0085697 CG41568 - http://flybase.org/reports/FBgn0085697 protein_coding_gene - - - CG41568 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262331 mir-999 mir-999 stem loop http://flybase.org/reports/FBgn0262331 miRNA_gene - - - "dme-mir-999, miR-999, mir-999, CR43038, miR999, dme-miR-999" - CR43038 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,visible,lethal - all die before end of P-stage,some die during pharate adult stage" wing FBgn0004040 yea6 yeast 6 http://flybase.org/reports/FBgn0004040 - gene - - - yea6 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065420 l(2)SH1525 lethal (2) SH1525 http://flybase.org/reports/FBgn0065420 gene - - - "l(2)SH1525, l(2)SH2 1525" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0051343 CG31343 - http://flybase.org/reports/FBgn0051343 protein_coding_gene metalloaminopeptidase activity ; GO:0070006 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 peptide binding ; GO:0042277 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 peptide catabolic process ; GO:0043171 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 "CG5839, BEST:GH20248, anon-WO0140519.86, CG31343" "IPR024571:ERAP1-like C-terminal domain, IPR001930:Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR014782:Peptidase M1, membrane alanine aminopeptidase, N-terminal, IPR034016:Aminopeptidase N-type" CG31343 27-Aug-18 DroID_v2018_08 "Drer\lnpep, Drer\anpepb, Drer\erap1b, Drer\si:ch211-106j24.1, Drer\si:ch211-149p5.1, Drer\enpep, Drer\erap1a, Drer\npepps, Drer\anpepa, Drer\si:ch211-276a23.5, Drer\si:ch211-198g19.1, Drer\erap2" "Scer\AAP1, Scer\TMA108, Scer\APE2" "Cele\T12E12.6, Cele\F49B2.6, Cele\VB0395L.1, Cele\mnp-1, Cele\AC3.5, Cele\Y53F4B.20, Cele\T16G12.1, Cele\Y67D8C.9, Cele\Y42A5A.1, Cele\R03G8.6, Cele\pam-1, Cele\R03G8.4, Cele\T07F10.1" "Xtro\lnpep, Xtro\anpep, Xtro\erap1, Xtro\lvrn, Xtro\npepps, Xtro\enpep" "Mmus\Lnpep, Mmus\Npepps, Mmus\Enpep, Mmus\Lvrn, Mmus\Trhde, Mmus\Erap1, Mmus\Anpep" "Hsap\NPEPPS, Hsap\LVRN, Hsap\LNPEP, Hsap\ANPEP, Hsap\TRHDE, Hsap\ENPEP, Hsap\ERAP1, Hsap\ERAP2" viable FBgn0032732 CG15168 - http://flybase.org/reports/FBgn0032732 protein_coding_gene inorganic cation transmembrane transporter activity ; GO:0022890 | inferred from biological aspect of ancestor with PANTHER:PTN000475936 cation transmembrane transport ; GO:0098655 | inferred from biological aspect of ancestor with PANTHER:PTN000475936 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000475936 early endosome ; GO:0005769 | inferred from biological aspect of ancestor with PANTHER:PTN000475936 Golgi apparatus ; GO:0005794 | inferred from biological aspect of ancestor with PANTHER:PTN000475936 ER membrane protein complex ; GO:0072546 | inferred from biological aspect of ancestor with PANTHER:PTN000475936 "BcDNA:RE09053, CG15168" IPR018937:Magnesium transporter CG15168 27-Aug-18 DroID_v2018_08 Drer\mmgt1 - Cele\emc-5 Xtro\mmgt1 "Mmus\Mmgt1, Mmus\Mmgt2" Hsap\MMGT1 "partially lethal - majority die,some die during pupal stage" FBgn0050043 CG30043 - http://flybase.org/reports/FBgn0050043 protein_coding_gene - - - "CG13161, CG30043" IPR007484:Peptidase M28 CG30043 27-Aug-18 DroID_v2018_08 Drer\LOC100330918 "Scer\PFF1, Scer\APE3, Scer\YDR415C, Scer\VPS70" "Cele\C44B7.11, Cele\B0495.7" Xtro\ermp1 Mmus\Ermp1 Hsap\ERMP1 viable FBgn0260313 GSd445 - http://flybase.org/reports/FBgn0260313 gene - - - GSd445 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0031204 CG9562 - http://flybase.org/reports/FBgn0031204 protein_coding_gene - - - "tartan/capricious-like, CT16794, CG9562" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0053727 snmRNA:430a snmRNA:430:CR33727 http://flybase.org/reports/FBgn0053727 non_protein_coding_gene - - - "CR33727, snmRNA:430:CR33727" - CR33727 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0015851 anon-10Cd anon-10Cd http://flybase.org/reports/FBgn0015851 - gene - - - anon-10Cd - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065367 l(2)SH1715 lethal (2) SH1715 http://flybase.org/reports/FBgn0065367 gene - - - "l(2)SH1715, l(2)SH2 1715" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0026353 Su(SuRaf1)2 Su(SuRaf1)2 http://flybase.org/reports/FBgn0026353 - gene - - - "Su[Su(Raf)1]2, Su(SuRaf1)2" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0029522 CG13373 - http://flybase.org/reports/FBgn0029522 protein_coding_gene - - - CG13373 IPR022773:Siva CG13373 27-Aug-18 DroID_v2018_08 Drer\siva1 - - Xtro\siva1 Mmus\Siva1 Hsap\SIVA1 "viable,fertile" FBgn0001007 fs(3)6m45 female sterile (3) 6m45 http://flybase.org/reports/FBgn0001007 - gene - - - fs(3)6m45 - - 27-Aug-18 DroID_v2018_08 - - - - - - female sterile "oocyte,ovary" FBgn0033753 Cyp301a1 Cyp301a1 http://flybase.org/reports/FBgn0033753 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 tergite morphogenesis ; GO:0007490 | inferred from mutant phenotype" - "301a1, CG8587, Cyp301a1, Cyp301A1" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I" CG8587 27-Aug-18 DroID_v2018_08 "Drer\cyp27a1.2, Drer\zgc:136333, Drer\cyp11a2, Drer\cyp27a1.4, Drer\cyp11c1, Drer\cyp27a7, Drer\cyp27b1, Drer\si:dkey-91i10.3, Drer\si:ch211-113j14.1, Drer\cyp24a1, Drer\cyp27c1" Scer\DIT2 "Cele\cyp-37B1, Cele\cyp-44A1" "Xtro\cyp27b1, Xtro\LOC100145331, Xtro\cyp27c1, Xtro\cyp11a1, Xtro\cyp24a1, Xtro\cyp27a1" "Mmus\Cyp24a1, Mmus\Cyp27a1, Mmus\Cyp11b1, Mmus\Cyp27b1, Mmus\Cyp11a1, Mmus\Cyp11b2" "Hsap\CYP24A1, Hsap\CYP27C1, Hsap\CYP11B1, Hsap\CYP11A1, Hsap\CYP27A1, Hsap\CYP11B2, Hsap\CYP27B1" "viable,fertile,visible,recessive,partially lethal - majority live,body color defective" "tergite,adult cuticle,mesothoracic tergum" FBgn0005687 pom pomegranate http://flybase.org/reports/FBgn0005687 - gene molecular_function ; GO:0003674 | no biological data available compound eye development ; GO:0048749 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available pom - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive" "eye,ommatidium" FBgn0043571 SK2-3 SK2-3 http://flybase.org/reports/FBgn0043571 gene - - - SK2-3 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0267074 asRNA:CR45518 - http://flybase.org/reports/FBgn0267074 non_protein_coding_gene - - - CR45518 - CR45518 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038373 CG4546 - http://flybase.org/reports/FBgn0038373 protein_coding_gene "kinase activity ; GO:0016301 | inferred from electronic annotation with InterPro:IPR022413, InterPro:IPR022414, InterPro:IPR022415" multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay CG4546 "IPR000749:ATP:guanido phosphotransferase, IPR014746:Glutamine synthetase/guanido kinase, catalytic domain, IPR022413:ATP:guanido phosphotransferase, N-terminal, IPR022414:ATP:guanido phosphotransferase, catalytic domain, IPR022415:ATP:guanido phosphotransferase active site" CG4546 27-Aug-18 DroID_v2018_08 "Drer\ckmb, Drer\ckba, Drer\ckmt1, Drer\ckmt2b, Drer\ckmt2a, Drer\ckma, Drer\ckbb" - "Cele\ZC434.8, Cele\F32B5.1, Cele\W10C8.5, Cele\argk-1, Cele\F46H5.3, Cele\F11G11.13" "Xtro\ckm, Xtro\ckmt1b, Xtro\ckb" "Mmus\Ckm, Mmus\Ckmt2, Mmus\Mycbp, Mmus\Ckb, Mmus\Ckmt1" "Hsap\MYCBP, Hsap\CKM, Hsap\CKMT1A, Hsap\CKMT2, Hsap\CKMT1B, Hsap\CKB" viable FBgn0013454 fs(2)neo11 fs(2)neo11 http://flybase.org/reports/FBgn0013454 - gene - - - fs(2)neo11 - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,fertile" FBgn0082189 l(3)S012606 lethal (3) S012606 http://flybase.org/reports/FBgn0082189 gene - - - l(3)S012606 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0264881 CG44072 - http://flybase.org/reports/FBgn0264881 protein_coding_gene - - - CG44072 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266850 lncRNA:CR45311 - http://flybase.org/reports/FBgn0266850 non_protein_coding_gene - - - CR45311 - CR45311 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031646 snsl - http://flybase.org/reports/FBgn0031646 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG2837 - CG2837 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0063408 l(3)3450-O lethal (3) 3450-O http://flybase.org/reports/FBgn0063408 gene - - - l(3)3450-O - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0028468 rtet tetracycline resistance http://flybase.org/reports/FBgn0028468 protein_coding_gene tetracycline transporter activity ; GO:0008493 | inferred from biological aspect of ancestor with PANTHER:PTN001921260 tetracycline transport ; GO:0015904 | inferred from biological aspect of ancestor with PANTHER:PTN001921260 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN001921112 oogenesis ; GO:0048477 | inferred from mutant phenotype "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005829, InterPro:IPR011701 brush border membrane ; GO:0031526 | inferred from biological aspect of ancestor with PANTHER:PTN001921260" "CG5760, Drtet, l(3)07086, BcDNA:LD28419, anon-WO0119857.1, rtet" "IPR005829:Sugar transporter, conserved site, IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG5760 27-Aug-18 DroID_v2018_08 Drer\mfsd10 "Scer\SGE1, Scer\YCR023C" "Cele\Y71G12B.25, Cele\F10D7.2, Cele\unc-17" Xtro\mfsd10 Mmus\Mfsd10 Hsap\MFSD10 "viable,fertile,lethal,recessive,female sterile,lethal - all die before end of larval stage,some die during larval stage" "ovariole,germline clone,egg" FBgn0267037 asRNA:CR45481 - http://flybase.org/reports/FBgn0267037 non_protein_coding_gene - - - CR45481 - CR45481 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260330 GSd482 - http://flybase.org/reports/FBgn0260330 gene - - - GSd482 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve,segmental nerve" FBgn0266916 Cenp-C Centromeric protein-C http://flybase.org/reports/FBgn0266916 protein_coding_gene - "protein localization to kinetochore ; GO:0034501 | inferred from mutant phenotype chromosome segregation ; GO:0007059 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype protein localization to chromosome, centromeric region ; GO:0071459 | inferred from mutant phenotype mitotic metaphase plate congression ; GO:0007080 | inferred from mutant phenotype regulation of centromere complex assembly ; GO:0090230 | inferred from direct assay female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype regulation of centromere complex assembly ; GO:0090230 | inferred from mutant phenotype regulation of stem cell differentiation ; GO:2000736 | inferred from mutant phenotype kinetochore assembly ; GO:0051382 | inferred from mutant phenotype" "kinetochore ; GO:0000776 | inferred from direct assay kinetochore ; GO:0000776 | colocalizes_with inferred from direct assay chromosome, centromeric region ; GO:0000775 | inferred from direct assay condensed nuclear chromosome, centromeric region ; GO:0000780 | inferred from direct assay chromosome, centromeric region ; GO:0000775 |" "cenp-C, Cenp-C, CG31258, CenpC, CENP-C, l(3)85Aa, L1, CG11745, CG11746, CLD1, l(3)SH157, l(2)SH3 157" - CG31258 27-Aug-18 DroID_v2018_08 Drer\krtcap2 - Cele\set-2 - Mmus\Krtcap2 Hsap\KRTCAP2 DRSC14371 E -1.229021924 -0.012567605 -0.04471976 -1.960457999 -1.057280315 1.08633189 FBgn0037874 Tctp Translationally controlled tumor protein http://flybase.org/reports/FBgn0037874 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from sequence or structural similarity with UniProtKB:P13693 calcium ion binding ; GO:0005509 | inferred from biological aspect of ancestor with PANTHER:PTN000241815 guanyl-nucleotide exchange factor activity ; GO:0005085 | inferred from direct assay Ras guanyl-nucleotide exchange factor activity ; GO:0005088 | NOT inferred from direct assay microtubule binding ; GO:0008017 | inferred from biological aspect of ancestor with PANTHER:PTN000241815 positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype cellular response to gamma radiation ; GO:0071480 | inferred from mutant phenotype double-strand break repair ; GO:0006302 | inferred from mutant phenotype positive regulation of histone phosphorylation ; GO:0033129 | inferred from direct assay positive regulation of cell size ; GO:0045793 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from mutant phenotype intra-S DNA damage checkpoint ; GO:0031573 | inferred from mutant phenotype regulation of stem cell differentiation ; GO:2000736 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay tubulin complex ; GO:0045298 | colocalizes_with inferred from sequence or structural similarity with UniProtKB:P13693 polytene chromosome ; GO:0005700 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000241815 "dTCTP, CG4800, TCTP, Tctp" "IPR018103:Translationally controlled tumour protein, conserved site, IPR018105:Translationally controlled tumour protein, IPR011057:Mss4-like, IPR034737:Translationally controlled tumor protein (TCTP) domain" CG4800 27-Aug-18 DroID_v2018_08 Drer\tpt1 Scer\TMA19 Cele\tct-1 Xtro\tpt1 Mmus\Tpt1 "Hsap\FLJ44635, Hsap\TPT1" "viable,mitotic cell cycle defective,maternal effect,lethal,recessive,small body,radiation sensitive,DNA repair defective,visible,decreased cell size,decreased cell number,lethal - all die before end of larval stage,some die during third instar larval stage,somatic clone,lethal - all die before end of first instar larval stage,some die during first instar larval stage,partially lethal - majority die,some die during pupal stage" "eye,wing,1st posterior cell,imaginal disc,somatic clone,trichogen cell,mesothoracic tergum" FBgn0267585 lncRNA:CR45923 - http://flybase.org/reports/FBgn0267585 non_protein_coding_gene - - - "CR45923, CR44101, CG17478, CG40280" - CR45923 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0026250 eIF1A eukaryotic translation initiation factor 1A http://flybase.org/reports/FBgn0026250 "FBgn0025531, FBgn0025959, FBgn0038594, FBgn0062638" protein_coding_gene "translation initiation factor activity ; GO:0003743 | inferred from electronic annotation with InterPro:IPR001253, InterPro:IPR006196, InterPro:IPR018104 translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity" "translational initiation ; GO:0006413 | inferred from electronic annotation with InterPro:IPR001253, InterPro:IPR006196, InterPro:IPR018104 translational initiation ; GO:0006413 | inferred from sequence or structural similarity phagocytosis ; GO:0006909 | inferred from mutant phenotype translation ; GO:0006412 | inferred from sequence or structural similarity smoothened signaling pathway ; GO:0007224 | inferred from genetic interaction with smo" nucleoplasm ; GO:0005654 | inferred from direct assay cytosol ; GO:0005829 | inferred from sequence or structural similarity cytosol ; GO:0005829 | inferred from direct assay eukaryotic 43S preinitiation complex ; GO:0016282 | inferred from sequence or structural similarity "eIF1A, group I, Group I, CG8053, D-eIF1A, eIF-4c, D-eIF4c, anon-EST:Liang-2.3, clone 2.3, EP(3)0935, EP935, anon-EST:Posey4, eIF-1A, lincRNA.S7087" "IPR018104:Translation initiation factor 1A (eIF-1A), conserved site, IPR001253:Translation initiation factor 1A (eIF-1A), IPR006196:RNA-binding domain, S1, IF1 type, IPR012340:Nucleic acid-binding, OB-fold" CG8053 27-Aug-18 DroID_v2018_08 "Drer\eif1axb, Drer\eif1axa" Scer\TIF11 Cele\eif-1.A Xtro\eif1ax "Mmus\Eif1a, Mmus\Gm2016, Mmus\Gm2022, Mmus\Gm8300, Mmus\Gm2046, Mmus\Gm21936, Mmus\Eif1ax, Mmus\Gm5662, Mmus\Gm21319, Mmus\Gm4027, Mmus\BB287469" "Hsap\LOC107984923, Hsap\EIF1AX, Hsap\EIF1AY" "viable,fertile,lethal,recessive,cell lethalcell lethal,somatic clone" DRSC16937 I -3.735674488 -1.796659258 -0.15675353 -1.300122881 0.70594744 1.456308064 FBgn0058142 CG40142 - http://flybase.org/reports/FBgn0058142 protein_coding_gene - - - CG40142 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0014277 l(2)k16904 lethal (2) k16904 http://flybase.org/reports/FBgn0014277 - gene - - - "l(2)169/4, l(2)k16904" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0003622 Su(var)2-147 Suppressor of variegation 2-147 http://flybase.org/reports/FBgn0003622 - gene - - - Su(var)2-147 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034136 DAT Dopamine transporter http://flybase.org/reports/FBgn0034136 protein_coding_gene cocaine binding ; GO:0019811 | inferred from direct assay dopamine transmembrane transporter activity ; GO:0005329 | inferred from direct assay dopamine:sodium symporter activity ; GO:0005330 | inferred from biological aspect of ancestor with PANTHER:PTN000746001 circadian sleep/wake cycle ; GO:0042745 | inferred from direct assay sleep ; GO:0030431 | inferred from mutant phenotype regulation of presynaptic cytosolic calcium ion concentration ; GO:0099509 | inferred from mutant phenotype dopamine transport ; GO:0015872 | inferred from direct assay response to odorant ; GO:1990834 | inferred from mutant phenotype dopamine uptake involved in synaptic transmission ; GO:0051583 | inferred from biological aspect of ancestor with PANTHER:PTN000746001 circadian sleep/wake cycle ; GO:0042745 | inferred from mutant phenotype adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 neuron projection ; GO:0043005 | inferred from biological aspect of ancestor with PANTHER:PTN000746001 "CG8380, fmn, DAT, dDAT, DmDAT, fumin, dat" IPR000175:Sodium:neurotransmitter symporter CG8380 27-Aug-18 DroID_v2018_08 "Drer\slc6a13, Drer\slc6a11a, Drer\si:ch211-132b12.6, Drer\slc6a16a, Drer\slc6a2, Drer\slc6a15, Drer\slc6a14, Drer\zgc:158225, Drer\slc6a6a, Drer\slc6a16b, Drer\slc6a18, Drer\slc6a5, Drer\slc6a19a.1, Drer\slc6a13, Drer\slc6a1l, Drer\si:ch211-117c9.5, Drer\slc6a13l, Drer\slc6a19a.2, Drer\si:ch211-132b12.2, Drer\slc6a4b, Drer\slc6a9, Drer\slc6a1b, Drer\slc6a8, Drer\slc6a19b, Drer\slc6a4a, Drer\slc6a6b, Drer\slc6a17, Drer\slc6a1a, Drer\si:ch211-132b12.1" - "Cele\dat-1, Cele\snf-11, Cele\snf-3, Cele\snf-6, Cele\mod-5" "Xtro\slc6a8, Xtro\slc6a12, Xtro\slc6a2, Xtro\slc6a6, Xtro\slc6a4, Xtro\slc6a16, Xtro\slc6a17, Xtro\slc6a13, Xtro\slc6a5, Xtro\slc6a15, Xtro\LOC100127682, Xtro\slc6a1, Xtro\slc6a3, Xtro\slc6a19, Xtro\slc6a7, Xtro\slc6a14.2, Xtro\slc6a9" "Mmus\Slc6a9, Mmus\Slc6a17, Mmus\Slc6a12, Mmus\Slc6a3, Mmus\Slc6a5, Mmus\Slc6a14, Mmus\Slc6a16, Mmus\Slc6a2, Mmus\Slc6a15, Mmus\Slc6a13, Mmus\Slc6a4, Mmus\Slc6a19, Mmus\Slc6a8, Mmus\Slc6a1, Mmus\Slc6a21, Mmus\Slc6a11, Mmus\Slc6a7, Mmus\Slc6a6, Mmus\Slc6a20a, Mmus\Slc6a20b, Mmus\Slc6a18" "Hsap\SLC6A13, Hsap\SLC6A11, Hsap\SLC6A2, Hsap\SLC6A3, Hsap\SLC6A19, Hsap\SLC6A6, Hsap\SLC6A20, Hsap\SLC6A9, Hsap\SLC6A8, Hsap\SLC6A7, Hsap\SLC6A17, Hsap\SLC6A12, Hsap\SLC6A18, Hsap\SLC6A1, Hsap\SLC6A4, Hsap\SLC6A5, Hsap\SLC6A15, Hsap\SLC6A16, Hsap\SLC6A14" "behavior defective,hyperactive,chemical conditional,locomotor behavior defective,circadian rhythm defective,viable,fertile,sleep defective,visible" mesothoracic tergum FBgn0016072 su(w[a])::tra su(w[a])::tra http://flybase.org/reports/FBgn0016072 - engineered_fusion_gene - - - su(w[a])::tra - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0046776 CR14033 - http://flybase.org/reports/FBgn0046776 pseudogene_attribute - - - "BcDNA:LD26231, BcDNA:LD26673, CR14033, CG14033" - CR14033 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC02358 E 1.184358107 0.841403925 1.551278363 3.273890028 0.536744075 0.112569003 FBgn0259657 B2037 - http://flybase.org/reports/FBgn0259657 gene - - - B2037 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "leg,proximal,scutellum" FBgn0036164 CG7543 - http://flybase.org/reports/FBgn0036164 protein_coding_gene - - - CG7543 - - 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0065285 l(2)SH2022 lethal (2) SH2022 http://flybase.org/reports/FBgn0065285 gene - - - "l(2)SH2022, l(2)SH2 2022" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0029074 l(1)G0145 lethal (1) G0145 http://flybase.org/reports/FBgn0029074 gene - - - l(1)G0145 - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0022893 Df31 Decondensation factor 31 http://flybase.org/reports/FBgn0022893 "FBgn0015041, FBgn0022155, FBgn0022348, FBgn0025987, FBgn0026586, FBgn0027759, FBgn0045899, FBtr0085919, FBtr0085920, FBpp0085274" protein_coding_gene histone binding ; GO:0042393 | inferred from direct assay nucleosome assembly ; GO:0006334 | inferred from direct assay chromatin organization ; GO:0006325 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay chromatin ; GO:0000785 | inferred from direct assay polytene chromosome ; GO:0005700 | colocalizes_with inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "anon-EST:Posey126, CG2207, anon1A4, DF 31, LD04967, clone 1.46, DF31, l(2)k05815, anon-EST:fe1A4, BEST:LD04967, anon-EST:Liang-1.46, anon-WO0153538.53, Df31" - CG2207 27-Aug-18 DroID_v2018_08 - - - - - - "viable,lethal,recessive,long lived,wild-type,partially lethal - majority die" chromatin FBgn0260599 2L2718 - http://flybase.org/reports/FBgn0260599 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L2718 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0267961 lncRNA:CR46241 - http://flybase.org/reports/FBgn0267961 non_protein_coding_gene - - - "CR46241, lincRNA.522" - CR46241 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0027615 CG6404 - http://flybase.org/reports/FBgn0027615 - protein_coding_gene - protein insertion into membrane ; GO:0051205 | inferred from electronic annotation with InterPro:IPR001708 respiratory chain complex IV assembly ; GO:0008535 | inferred from sequence or structural similarity with UniProtKB:Q15070 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR001708 mitochondrial envelope ; GO:0005740 | inferred from sequence or structural similarity with UniProtKB:Q15070 "BcDNA:GH02220, CG6404, OXA1" "IPR001708:Membrane insertase OXA1/ALB3/YidC, IPR028055:Membrane insertase YidC/Oxa1, C-terminal" CG6404 27-Aug-18 DroID_v2018_08 "Drer\oxa1l, Drer\cox18" "Scer\OXA1, Scer\COX18" "Cele\Y55F3AR.1, Cele\oxa-1" "Xtro\oxa1l, Xtro\cox18" "Mmus\Cox18, Mmus\Oxa1l" "Hsap\COX18, Hsap\OXA1L" DRSC09672 K 0.320060997 -0.359578719 -0.163800958 0.243142942 0.603791233 1.713725377 FBgn0011748 anon-M-SAR anonymous M/SAR sequence http://flybase.org/reports/FBgn0011748 - repeat_region - - - "centromere; lamin. centromeric beta-heterochromatin sequence, anon-M/SAR, anon-M-SAR" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037402 Vha14-2 Vacuolar H[+] ATPase 14kD subunit 2 http://flybase.org/reports/FBgn0037402 protein_coding_gene "proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from electronic annotation with InterPro:IPR005772 ATPase coupled ion transmembrane transporter activity ; GO:0042625 | inferred from biological aspect of ancestor with PANTHER:PTN001015339" ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from electronic annotation with InterPro:IPR005772 ATP hydrolysis coupled proton transport ; GO:0015991 | inferred by curator from GO:0033176 "proton-transporting V-type ATPase, V1 domain ; GO:0033180 | inferred from electronic annotation with InterPro:IPR005772 proton-transporting V-type ATPase complex ; GO:0033176 | inferred from sequence or structural similarity with Vha14-1 membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN001015339" "vha14-2, CG1076, Vha14-2" "IPR005772:ATPase, V1 complex, subunit F, eukaryotic, IPR008218:ATPase, V1 complex, subunit F" CG1076 27-Aug-18 DroID_v2018_08 Drer\atp6v1f Scer\VMA7 Cele\vha-9 Xtro\atp6v1f Mmus\Atp6v1f Hsap\ATP6V1F viable FBgn0039299 CG11854 - http://flybase.org/reports/FBgn0039299 protein_coding_gene - - extracellular space ; GO:0005615 | inferred from sequence or structural similarity with to CG11854 IPR010562:Haemolymph juvenile hormone binding CG11854 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0065736 l(2)SH0541 lethal (2) SH0541 http://flybase.org/reports/FBgn0065736 gene - - - "l(2)SH0541, l(2)SH2 0541" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0004994 Cor Corroded eye http://flybase.org/reports/FBgn0004994 - gene - - - Cor - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,dominant" eye FBgn0053669 CG33669 - http://flybase.org/reports/FBgn0053669 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "bs03a05.y1, NEST:bs03a05, CG33669" - CG33669 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0285970 CG32500 TO42 http://flybase.org/reports/FBgn0029115 gene iron-sulfur cluster binding ; GO:0051536 | inferred from electronic annotation with InterPro:IPR001075 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001075 "iron-sulfur cluster assembly ; GO:0016226 | inferred from electronic annotation with InterPro:IPR001075, InterPro:IPR017065" - "clot#9754, TO42" "IPR000629:ATP-dependent RNA helicase DEAD-box, conserved site, IPR014824:Scaffold protein Nfu/NifU, N-terminal, IPR001075:NIF system FeS cluster assembly, NifU, C-terminal, IPR017065:NFU1 iron-sulfur cluster scaffold homologue" - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0011215 cash cashews http://flybase.org/reports/FBgn0011215 - gene - spermatid development ; GO:0007286 | inferred from mutant phenotype - "cas, cash" - - 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,recessive" FBgn0044083 E(rst)H186 E(rst)H186 http://flybase.org/reports/FBgn0044083 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "H186, E(rst)H186" - - 27-Aug-18 DroID_v2018_08 - - - - - - viable eye FBgn0040737 Tango8 Transport and Golgi organization 8 http://flybase.org/reports/FBgn0040737 protein_coding_gene molecular_function ; GO:0003674 | no biological data available Golgi organization ; GO:0007030 | inferred from mutant phenotype protein secretion ; GO:0009306 | inferred from mutant phenotype endoplasmic reticulum ; GO:0005783 | inferred from direct assay "CG14503, TANGO8, Tango8" - CG14503 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267612 lncRNA:CR45950 - http://flybase.org/reports/FBgn0267612 non_protein_coding_gene - - - CR45950 - CR45950 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039031 Gbp3 Growth-blocking peptide 3 http://flybase.org/reports/FBgn0039031 protein_coding_gene cytokine activity ; GO:0005125 | inferred from sequence or structural similarity with Gbp1 signal transduction ; GO:0007165 | inferred from sequence or structural similarity with Gbp1 cellular_component ; GO:0005575 | no biological data available "BcDNA:RH17470, CG17244, Gbp3, GBP3" - CG17244 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC15206 K 0.463009169 -0.325969033 1.052178418 -0.225560437 -1.608280657 -0.859813274 FBgn0263476 snoRNA:CG32479-b - http://flybase.org/reports/FBgn0263476 snoRNA_gene - - - snoRNA:CG32479-b - CR43591 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033461 CG12923 - http://flybase.org/reports/FBgn0033461 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12923 IPR031732:Protein of unknown function DUF4729 CG12923 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0016842 l(1)N15 lethal (1) N15 http://flybase.org/reports/FBgn0016842 - gene - - - "l(1)N15, N15" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0038879 CG17298 - http://flybase.org/reports/FBgn0038879 protein_coding_gene - - - "CT35916, BcDNA:RH37844, CG17298" - CG17298 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0265597 rad radish http://flybase.org/reports/FBgn0265597 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781 GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with RapGAP1 regulation of small GTPase mediated signal transduction ; GO:0051056 | inferred from electronic annotation with InterPro:IPR000331 anesthesia-resistant memory ; GO:0007615 | inferred from direct assay olfactory learning ; GO:0008355 | traceable author statement anesthesia-resistant memory ; GO:0007615 | traceable author statement regulation of heart contraction ; GO:0008016 | inferred from mutant phenotype neuronal cell body ; GO:0043025 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay axon ; GO:0030424 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG44424, rad, CG42629, CG42628, rsh, CG15720, CG4346, radish, CG4368, CG18646, Rad, FBpp0073550, R5_X:12971309..12973132" "IPR000210:BTB/POZ domain, IPR000331:Rap GTPase activating protein domain, IPR011333:SKP1/BTB/POZ domain, IPR001781:Zinc finger, LIM-type" CG44424 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-182d3.1, Drer\zmp:0000001168, Drer\si:dkey-166d12.2, Drer\sipa1l3, Drer\sipa1l2, Drer\rap1gap2a, Drer\sipa1l1, Drer\LOC101882292, Drer\ralgapa2" - Cele\sipa-1 "Xtro\sipa1l1, Xtro\rap1gap, Xtro\ralgapa1, Xtro\rap1gap2, Xtro\garnl3" "Mmus\Rap1gap2, Mmus\Sipa1l1, Mmus\Sipa1, Mmus\Ralgapa1, Mmus\Sipa1l3, Mmus\Ralgapa2, Mmus\Rap1gap, Mmus\Sipa1l2, Mmus\Garnl3" "Hsap\SIPA1L2, Hsap\RAP1GAP, Hsap\SIPA1L1, Hsap\SIPA1, Hsap\SIPA1L3, Hsap\RALGAPA1, Hsap\GARNL3, Hsap\RALGAPA2, Hsap\RAP1GAP2" DRSC22865 IE -1.527563262 -0.024275387 -0.767896929 -1.776137846 -0.466784737 -0.017405572 FBgn0037175 CG14455 - http://flybase.org/reports/FBgn0037175 protein_coding_gene enzyme activator activity ; GO:0008047 | inferred from electronic annotation with InterPro:IPR028996 ganglioside catabolic process ; GO:0006689 | inferred from electronic annotation with InterPro:IPR028996 - CG14455 "IPR028996:Ganglioside GM2 activator, IPR010512:Protein of unknown function DUF1091" CG14455 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0053127 CG33127 - http://flybase.org/reports/FBgn0053127 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - CG33127 "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site" CG33127 27-Aug-18 DroID_v2018_08 "Drer\prss60.2, Drer\prss60.1, Drer\try, Drer\prss60.3" - "Cele\try-3, Cele\svh-1" - "Mmus\1810009J06Rik, Mmus\2210010C04Rik, Mmus\Klk1b3" - FBgn0061166 l(1)3Ar lethal (1) 3Ar http://flybase.org/reports/FBgn0061166 gene - - - l(1)3Ar - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0035878 CG7182 - http://flybase.org/reports/FBgn0035878 protein_coding_gene - - - CG7182 IPR013126:Heat shock protein 70 family CG7182 27-Aug-18 DroID_v2018_08 "Drer\hsp70.1, Drer\hsp70l, Drer\hspa5, Drer\hspa14, Drer\hspa12b, Drer\si:dkey-4p15.3, Drer\hsp70.2, Drer\hspa4l, Drer\hspa12a, Drer\hsc70, Drer\hspa13, Drer\si:ch211-199o1.2, Drer\hspa8" "Scer\KAR2, Scer\SSA2, Scer\SSQ1, Scer\SSB2, Scer\SSA4, Scer\SSZ1, Scer\SSA1, Scer\SSB1, Scer\SSA3" Cele\F11F1.1 "Xtro\hspa1l, Xtro\hspa1b, Xtro\hspa14, Xtro\hspa1a, Xtro\hsp70, Xtro\hspa8, Xtro\hspa5, Xtro\hspa2, Xtro\hspa12b, Xtro\hspa13" "Mmus\Hspa1l, Mmus\Hspa12b, Mmus\Hspa13, Mmus\Hspa4l, Mmus\Hspa2, Mmus\Hspa1a, Mmus\Hspa14, Mmus\Hspa4, Mmus\Hspa12a, Mmus\Hspa5, Mmus\Hspa8" "Hsap\HSPA1B, Hsap\HSPA8, Hsap\HSPA1L, Hsap\HSPA12B, Hsap\HSPA2, Hsap\HSPA4L, Hsap\HSPA5, Hsap\HSPA13, Hsap\HSPA14, Hsap\HSPA12A, Hsap\HSPA6, Hsap\HSPA1A" viable embryonic/larval hemocyte | third instar larval stage FBgn0019885 anon-63BC-T2 anon-63BC-T2 http://flybase.org/reports/FBgn0019885 - gene - - - "T2, 63B-T2, anon-63BC-T2" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038653 Octalpha2R - http://flybase.org/reports/FBgn0038653 protein_coding_gene heterotrimeric G-protein binding ; GO:0032795 | inferred from sequence or structural similarity with HGNC:281 G-protein coupled amine receptor activity ; GO:0008227 | inferred from sequence or structural similarity with HGNC:281 adrenergic receptor activity ; GO:0004935 | inferred from biological aspect of ancestor with PANTHER:PTN000664502 cell-cell signaling ; GO:0007267 | inferred from biological aspect of ancestor with PANTHER:PTN000664502 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with HGNC:281 adenylate cyclase-activating adrenergic receptor signaling pathway ; GO:0071880 | inferred from biological aspect of ancestor with PANTHER:PTN001205212 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000664502 integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity with HGNC:281 CG18208 "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG18208 27-Aug-18 DroID_v2018_08 "Drer\drd2b, Drer\htr1aa, Drer\drd2l, Drer\adra2db, Drer\htr1b, Drer\htr1d, Drer\adra2a, Drer\adra2da, Drer\LOC100330650, Drer\adra2c, Drer\drd2a, Drer\adra2b" - "Cele\ser-2, Cele\ser-4, Cele\ser-7, Cele\octr-1" "Xtro\adra2c, Xtro\adra2b, Xtro\adra2a, Xtro\htr1b" "Mmus\Htr1a, Mmus\Adra2c, Mmus\Olfr683, Mmus\Olfr919, Mmus\Adra2a, Mmus\Htr1b, Mmus\Olfr1101, Mmus\Adra2b, Mmus\Olfr275, Mmus\Drd2, Mmus\Htr1f, Mmus\Olfr684, Mmus\Olfr150, Mmus\Htr7, Mmus\Htr1d" "Hsap\HTR1F, Hsap\OR56A4, Hsap\HTR1B, Hsap\OR56A5, Hsap\HTR7, Hsap\ADRA2C, Hsap\HTR1A, Hsap\HTR1D, Hsap\DRD2, Hsap\OR5T1, Hsap\OR13F1, Hsap\ADRA2A, Hsap\OR56A1, Hsap\ADRA2B" "viable,fertile,visible" mesothoracic tergum FBgn0035648 CG13288 - http://flybase.org/reports/FBgn0035648 protein_coding_gene - - integral component of membrane ; GO:0016021 | inferred from sequence model "CG13288, dmCG13288" IPR031720:Protein of unknown function DUF4728 CG13288 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0266107 mei-175 meiotic 175 http://flybase.org/reports/FBgn0266107 gene - female meiotic division ; GO:0007143 | inferred from mutant phenotype - mei-175 - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,meiotic cell cycle defective,female" FBgn0083999 CG41432 - http://flybase.org/reports/FBgn0083999 protein_coding_gene - - - CG41432 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267245 lncRNA:CR45685 - http://flybase.org/reports/FBgn0267245 non_protein_coding_gene - - - CR45685 - CR45685 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266745 CG45218 - http://flybase.org/reports/FBgn0266745 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG45218 - CG45218 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0261926 CG42793 - http://flybase.org/reports/FBgn0261926 protein_coding_gene - - - "CG42793, CG43203" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033043 Or42b Odorant receptor 42b http://flybase.org/reports/FBgn0033043 protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from mutant phenotype odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b sensory perception of smell ; GO:0007608 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a "42b, DOR118, 41E.1, CG12754, Or42b, OR42b" "IPR004117:Olfactory receptor, insect" CG12754 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile,smell perception defective" FBgn0030091 CG7065 - http://flybase.org/reports/FBgn0030091 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG7065 - CG7065 27-Aug-18 DroID_v2018_08 "Drer\smarca4a, Drer\smarca2" "Scer\STH1, Scer\SNF2" "Cele\C52B9.8, Cele\swsn-4" - "Mmus\Smarca4, Mmus\Smarca2" "Hsap\SMARCA4, Hsap\SMARCA2" "lethal,some die during pupal stage,viable" DRSC25280 K 0.304504596 1.188708194 1.426216408 1.069094513 1.723976147 0.825441875 FBgn0265015 S042938 - http://flybase.org/reports/FBgn0265015 gene - - - S042938 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0084606 1038 1038 http://flybase.org/reports/FBgn0084606 gene - - - 1038 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0026636 l(2)k15801 lethal (2) k15801 http://flybase.org/reports/FBgn0026636 - gene - - - l(2)k15801 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0015217 E(var)53E Enhancer of variegation 53E http://flybase.org/reports/FBgn0015217 - gene - - - "E(var)2-53E, E(var)53E" - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive,enhancer of variegation,dominant" FBgn0267531 asRNA:CR45871 - http://flybase.org/reports/FBgn0267531 non_protein_coding_gene - - - CR45871 - CR45871 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002731 mfs(3)G male female sterile G http://flybase.org/reports/FBgn0002731 - gene - - - "fs(3)4, mfs(3)G" - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,male sterile,viable,poor,visible" "egg chamber,adult fat body,metathoracic tibia,metathoracic tarsal segment" FBgn0036157 CG7560 - http://flybase.org/reports/FBgn0036157 protein_coding_gene methylenetetrahydrofolate reductase (NAD(P)H) activity ; GO:0004489 | inferred from biological aspect of ancestor with PANTHER:PTN000472667 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR003171 methionine metabolic process ; GO:0006555 | inferred from electronic annotation with InterPro:IPR003171 one-carbon metabolic process ; GO:0006730 | inferred from biological aspect of ancestor with PANTHER:PTN000472667 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000472667 "gh18008, BEST:GH18008, CG7560" "IPR003171:Methylenetetrahydrofolate reductase, IPR029041:FAD-linked oxidoreductase-like" CG7560 27-Aug-18 DroID_v2018_08 Drer\mthfr "Scer\MET12, Scer\MET13" Cele\mthf-1 "Xtro\mthfr, Xtro\lcor" Mmus\Mthfr Hsap\MTHFR viable FBgn0033481 CG12920 - http://flybase.org/reports/FBgn0033481 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12920 - CG12920 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0264517 asRNA:CR43916 - http://flybase.org/reports/FBgn0264517 non_protein_coding_gene - - - CR43916 - CR43916 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000803 fs(1)de14 female sterile (1) defective eggs 14 http://flybase.org/reports/FBgn0000803 - gene - - - "de14, fs(1)de14" - - 27-Aug-18 DroID_v2018_08 - - - - - - female sterile "dorsal appendage,chorion,endochorion" FBgn0264702 asRNA:CR43971 - http://flybase.org/reports/FBgn0264702 non_protein_coding_gene - - - CR43971 - CR43971 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0083997 CG41355 - http://flybase.org/reports/FBgn0083997 protein_coding_gene - - - CG41355 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004073 fs(2)mel7 female sterile (2) maternal effect lethal 7 http://flybase.org/reports/FBgn0004073 - gene - - - "Mel 7, fs(2)mel7" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,semidominant,some die during embryonic stage" "embryonic/larval posterior spiracle,maternal effect" FBgn0016043 lup-1 loop unfolding protein-1 http://flybase.org/reports/FBgn0016043 - gene - sperm axoneme assembly ; GO:0007288 | inferred from mutant phenotype - "ms(3)HB223, lup-1, 155-34" - - 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,recessive,female semi-sterile,female sterile" "Y chromosome loop,spermatid axoneme,axonemal dynein complex,axonemal microtubule | ectopic,axonemal microtubule | supernumerary" FBgn0052946 CG32946 - http://flybase.org/reports/FBgn0052946 protein_coding_gene - - - CG32946 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085812 lncRNA:CR41601 - http://flybase.org/reports/FBgn0085812 non_protein_coding_gene - - - CR41601 - CR41601 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0010832 l(3)04069b lethal (3) 04069b http://flybase.org/reports/FBgn0010832 - gene - - - "l(3)04069, l(3)04069b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive,lethal" "crystal cell,plasmatocyte" FBgn0266990 lncRNA:CR45441 - http://flybase.org/reports/FBgn0266990 non_protein_coding_gene - - - CR45441 - CR45441 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0050073 Obp50b Odorant-binding protein 50b http://flybase.org/reports/FBgn0050073 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 extracellular region ; GO:0005576 | inferred from sequence model "CG30073, CG13940, Obp50b, DmelObp50b" IPR006170:Pheromone/general odorant binding protein CG30073 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0065477 l(2)SH1297 lethal (2) SH1297 http://flybase.org/reports/FBgn0065477 gene - - - "l(2)SH1297, l(2)SH2 1297" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0034417 CG15117 - http://flybase.org/reports/FBgn0034417 protein_coding_gene beta-glucuronidase activity ; GO:0004566 | inferred from biological aspect of ancestor with PANTHER:PTN000007257 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern carbohydrate metabolic process ; GO:0005975 | inferred from biological aspect of ancestor with PANTHER:PTN000007197 extracellular space ; GO:0005615 | inferred from direct assay intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000007197 CG15117 "IPR006101:Glycoside hydrolase, family 2, IPR006102:Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich, IPR006103:Glycoside hydrolase family 2, catalytic domain, IPR006104:Glycosyl hydrolases family 2, sugar binding domain, IPR008979:Galactose-binding domain-like, IPR017853:Glycoside hydrolase superfamily, IPR013783:Immunoglobulin-like fold, IPR023230:Glycoside hydrolase, family 2, conserved site, IPR023232:Glycoside hydrolase, family 2, active site" CG15117 27-Aug-18 DroID_v2018_08 Drer\gusb - Cele\Y105E8B.9 Xtro\gusb Mmus\Gusb "Hsap\GUSB, Hsap\LOC100653061" "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC06539 I -1.963157371 -1.045937417 -0.339340485 0.770838827 -0.984755744 -1.248662544 FBgn0033788 CG13323 - http://flybase.org/reports/FBgn0033788 protein_coding_gene - - - "FBgn0033788, CG13323" IPR031734:Transcription activator MBF2 CG13323 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0264368 asRNA:CR43820 - http://flybase.org/reports/FBgn0264368 non_protein_coding_gene - - - CR43820 - CR43820 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0067328 3N5 3N5 http://flybase.org/reports/FBgn0067328 gene molecular_function ; GO:0003674 | no biological data available wing disc development ; GO:0035220 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available 3N5 - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,somatic clone" "wing,posterior compartment,somatic clone" FBgn0030629 CG9123 - http://flybase.org/reports/FBgn0030629 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cell proliferation ; GO:0008283 | inferred from sequence or structural similarity with MGI:MGI:1915333 ribosomal large subunit biogenesis ; GO:0042273 | inferred from biological aspect of ancestor with PANTHER:PTN002336300 rRNA processing ; GO:0006364 | inferred from biological aspect of ancestor with PANTHER:PTN002336300 nucleolus ; GO:0005730 | inferred from sequence or structural similarity with MGI:MGI:1915333 CG9123 "IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain, IPR001680:WD40 repeat, IPR019775:WD40 repeat, conserved site" CG9123 27-Aug-18 DroID_v2018_08 "Drer\pak1ip1, Drer\wdr55" "Scer\JIP5, Scer\MAK11" Cele\Y44F5A.1 Xtro\pak1ip1 "Mmus\Pak1ip1, Mmus\Wdr55" "Hsap\WDR55, Hsap\PAK1IP1" viable FBgn0086058 snoRNA:Me18S-G1189 - http://flybase.org/reports/FBgn0086058 snoRNA_gene - - - "snoRNA:Me18S-G1189, Me18S-Gm1189, CR34687" - CR34687 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0027584 CG4757 - http://flybase.org/reports/FBgn0027584 - protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from biological aspect of ancestor with PANTHER:PTN000168392 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "GH05702, BcDNA:GH05741, CG4757, GH05741" "IPR002018:Carboxylesterase, type B, IPR019826:Carboxylesterase type B, active site, IPR029058:Alpha/Beta hydrolase fold" CG4757 27-Aug-18 DroID_v2018_08 "Drer\nlgn3b, Drer\si:ch211-93f2.1, Drer\ces3, Drer\cell, Drer\nlgn2b, Drer\nlgn2a, Drer\nlgn3a, Drer\cel.1, Drer\nlgn4b, Drer\nlgn4a, Drer\ces2, Drer\nlgn1" - "Cele\T28C12.5, Cele\nlg-1, Cele\Y71H2AM.13, Cele\K11G9.1, Cele\B0238.1, Cele\F15A8.6, Cele\ges-1, Cele\T28C12.4, Cele\R173.3, Cele\F56C11.6, Cele\K11G9.2, Cele\T07H6.1, Cele\F07C4.12" "Xtro\ces2, Xtro\nlgn4x, Xtro\ces3, Xtro\cel, Xtro\nlgn2, Xtro\nlgn3, Xtro\LOC100494782" "Mmus\Ces2e, Mmus\Ces1h, Mmus\Ces3b, Mmus\Cel, Mmus\Nlgn3, Mmus\Ces4a, Mmus\Ces5a, Mmus\Ces2c, Mmus\Ces3a, Mmus\Nlgn1, Mmus\Ces2g, Mmus\Ces1f, Mmus\Ces1b, Mmus\Ces2f, Mmus\Ces2h, Mmus\Nlgn2, Mmus\Ces2a, Mmus\Ces1e, Mmus\Ces1g, Mmus\Ces1d, Mmus\Ces2b, Mmus\Ces1c" "Hsap\CES3, Hsap\NLGN4Y, Hsap\NLGN2, Hsap\CEL, Hsap\NLGN4X, Hsap\CES1, Hsap\NLGN3, Hsap\CES4A, Hsap\CES5A, Hsap\CES2, Hsap\NLGN1" "visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,trichogen cell,mesothoracic tergum" FBgn0063389 snoRNA:Me18S-G1620 - http://flybase.org/reports/FBgn0063389 snoRNA_gene - - - "U25snoRNA, snoRNA:U25, CR32874, snoRNA:Me18S-G1620, Me18S-G1620(U25), snoRNA:U25:30E, DmSnR56, Dm_18S.007" - CR32874 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267024 asRNA:CR45468 - http://flybase.org/reports/FBgn0267024 non_protein_coding_gene - - - CR45468 - CR45468 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060404 l(3)S131010 lethal (3) S131010 http://flybase.org/reports/FBgn0060404 gene - - - "1310/10, l(3)S131010" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0013457 fs(2)neo5 fs(2)neo5 http://flybase.org/reports/FBgn0013457 - gene - - - fs(2)neo5 - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,lethal,maternal effect" FBgn0259973 Sfp79B Seminal fluid protein 79 http://flybase.org/reports/FBgn0259973 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "Sfp79B, CG42483" - CG42483 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267763 lncRNA:CR46094 - http://flybase.org/reports/FBgn0267763 non_protein_coding_gene - - - CR46094 - CR46094 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038816 Lrrk Leucine-rich repeat kinase http://flybase.org/reports/FBgn0038816 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR013684 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN001147562 protein kinase activity ; GO:0004672 | inferred from direct assay Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab5 inferred from physical interaction with Rab7 protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay protein serine/threonine kinase activity ; GO:0004674 | inferred from mutant phenotype protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9W596 signal transducer activity ; GO:0004871 | inferred from biological aspect of ancestor with PANTHER:PTN000584058 Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab18" "small GTPase mediated signal transduction ; GO:0007264 | inferred from electronic annotation with InterPro:IPR013684 axo-dendritic transport ; GO:0008088 | inferred from mutant phenotype regulation of microtubule cytoskeleton organization ; GO:0070507 | inferred from mutant phenotype negative regulation of dendrite morphogenesis ; GO:0050774 | inferred from mutant phenotype intracellular distribution of mitochondria ; GO:0048312 | inferred from mutant phenotype regulation of synapse maturation ; GO:0090128 | inferred from mutant phenotype regulation of terminal button organization ; GO:2000331 | inferred from mutant phenotype intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN000584058 autophagy ; GO:0006914 | inferred from mutant phenotype synapse organization ; GO:0050808 | inferred from mutant phenotype locomotion ; GO:0040011 | inferred from mutant phenotype neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype peptidyl-serine phosphorylation ; GO:0018105 | inferred from direct assay negative regulation of neuron death ; GO:1901215 | inferred from mutant phenotype retrograde transport, endosome to Golgi ; GO:0042147 | inferred from genetic interaction with Rab9 regulation of synaptic vesicle endocytosis ; GO:1900242 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from biological aspect of ancestor with PANTHER:PTN000584058 lysosome localization ; GO:0032418 | inferred from mutant phenotype inferred from genetic interaction with Rab7 establishment of Golgi localization ; GO:0051683 | inferred from mutant phenotype" neuromuscular junction ; GO:0031594 | inferred from direct assay lysosomal membrane ; GO:0005765 | inferred from direct assay dendritic shaft ; GO:0043198 | inferred from direct assay Golgi stack ; GO:0005795 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001147562 cytoplasm ; GO:0005737 | inferred from direct assay dendritic branch point ; GO:1990033 | inferred from direct assay late endosome membrane ; GO:0031902 | inferred from direct assay cell body ; GO:0044297 | inferred from direct assay "CT17358, dLRRK, CG5483, Lrrk, LRRK, lrrk, LRRK2, dLrrk" "IPR000719:Protein kinase domain, IPR001611:Leucine-rich repeat, IPR002110:Ankyrin repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR011047:Quinoprotein alcohol dehydrogenase-like superfamily, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR013684:Mitochondrial Rho-like, IPR017441:Protein kinase, ATP binding site, IPR032675:Leucine-rich repeat domain, L domain-like, IPR020683:Ankyrin repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR020859:Roc domain, IPR032171:C-terminal of Roc (COR) domain" CG5483 27-Aug-18 DroID_v2018_08 "Drer\lrrk2, Drer\ripk3, Drer\ripk4, Drer\zak, Drer\LOC405768, Drer\dstyk, Drer\si:ch211-120p12.3, Drer\pbk, Drer\ripk2, Drer\map3k9, Drer\map3k10, Drer\ascl1b, Drer\ripk1l, Drer\mos, Drer\lrrk1" - Cele\lrk-1 "Xtro\ankk1, Xtro\zak, Xtro\lrrk1, Xtro\map3k7, Xtro\map3k10, Xtro\pbk, Xtro\dstyk, Xtro\map3k9, Xtro\ripk1, Xtro\lrrk2, Xtro\LOC100490493, Xtro\ripk4, Xtro\mlkl" "Mmus\Zak, Mmus\Ripk4, Mmus\Lrrk1, Mmus\Lrrk2, Mmus\Mos, Mmus\BC021891, Mmus\Pbk, Mmus\Ripk1, Mmus\Mlkl, Mmus\Map3k11, Mmus\Dstyk, Mmus\Ripk2, Mmus\Ripk3, Mmus\Map3k7, Mmus\Map3k9, Mmus\Map3k10" "Hsap\PBK, Hsap\MAP3K7, Hsap\MAP3K10, Hsap\MAP3K9, Hsap\MAP3K21, Hsap\MOS, Hsap\RIPK1, Hsap\RIPK4, Hsap\MAP3K11, Hsap\MAP3K20, Hsap\MLKL, Hsap\LRRK1, Hsap\DSTYK, Hsap\LRRK2, Hsap\RIPK2, Hsap\RIPK3" "viable,neuroanatomy defective,chemical sensitive,locomotor behavior defective,female fertile,reduced,chemical resistant,female sterile,neurophysiology defective,female semi-sterile" "lysosomeCY2,type I bouton,neuromuscular junction,neuromuscular junctionMhc.PW,dopaminergic neuron,adult abdomen,female,dendritic arborizing neuron | third instar larval stage,NMJ bouton,mitochondrion" FBgn0262774 Su(E1)-H - http://flybase.org/reports/FBgn0262774 gene - - - Su(E1)-H - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002900 mus302 mutagen-sensitive 302 http://flybase.org/reports/FBgn0002900 - gene - - - "mus(3)302, mus302" - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,chemical sensitive,recessive,semidominant,radiation sensitive,female fertile,poor,DNA repair defective" FBgn0011047 l(3)AFA17 lethal (3) AFA17 http://flybase.org/reports/FBgn0011047 FBgn0005200 gene - - - l(3)AFA17 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0024492 BITP-15 BITP-15 http://flybase.org/reports/FBgn0024492 - gene - - - BITP-15 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036333 MICAL-like MICAL-like http://flybase.org/reports/FBgn0036333 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781 actin binding ; GO:0003779 | inferred from sequence or structural similarity - - "AAK93415, CG11259, MICAL-like" "IPR001715:Calponin homology domain, IPR001781:Zinc finger, LIM-type, IPR022735:Domain of unknown function DUF3585" CG11259 27-Aug-18 DroID_v2018_08 "Drer\micall2b, Drer\micall2a, Drer\mical3b, Drer\mical1, Drer\si:ch211-254c8.2, Drer\mical3a, Drer\micall1a" - - "Xtro\micall1, Xtro\micall2" "Mmus\Micall2, Mmus\2900011O08Rik, Mmus\Micall1" "Hsap\MICAL1, Hsap\MICALL2, Hsap\EHBP1, Hsap\MICALL1" "viable,fertile" FBgn0031103 CG12679 - http://flybase.org/reports/FBgn0031103 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12679 IPR032007:Protein of unknown function DUF4791 CG12679 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0052068 Adi1 Acireductone dioxygenase 1 http://flybase.org/reports/FBgn0052068 protein_coding_gene acireductone dioxygenase [iron(II)-requiring] activity ; GO:0010309 | inferred from electronic annotation with InterPro:IPR004313 oxidoreductase activity ; GO:0016491 | inferred from sequence or structural similarity with UniProtKB:Q9BV57 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR004313 L-methionine biosynthetic process from methylthioadenosine ; GO:0019509 | inferred from sequence or structural similarity with UniProtKB:Q9BV57 methionine biosynthetic process ; GO:0009086 | inferred from mutant phenotype methionine metabolic process ; GO:0006555 | inferred from mutant phenotype positive regulation of reproductive process ; GO:2000243 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:Q9BV57 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with UniProtKB:Q9BV57 nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q9BV57 "CG8000, CG32068, Adi1, Dadi1, adi1" "IPR004313:Acireductone dioxygenase ARD family, IPR011051:RmlC-like cupin domain, IPR014710:RmlC-like jelly roll fold, IPR027496:1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, eukaryotes" CG32068 27-Aug-18 DroID_v2018_08 "Drer\adi1, Drer\LOC554736" Scer\ADI1 "Cele\T01D1.4, Cele\F42F12.4, Cele\K07E1.1" Xtro\adi1 Mmus\Adi1 Hsap\ADI1 FBgn0263464 snoRNA:hts-a - http://flybase.org/reports/FBgn0263464 snoRNA_gene - - - "snoRNA:hts-a, snoHACA_05" - CR43579 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0020757 Cyp6a9-rAF4-2 Cytochrome P450-6a9 related AF4-2 http://flybase.org/reports/FBgn0020757 - gene - - - "P450, AF4-2, P-450, Cyp6a9-rAF4-2" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267448 asRNA:CR45798 - http://flybase.org/reports/FBgn0267448 non_protein_coding_gene - - - "CR45798, noncoding_18124" - CR45798 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0083950 side-VI - http://flybase.org/reports/FBgn0083950 protein_coding_gene - - - "CG14698, CG4695, CG34114, 34114" "IPR007110:Immunoglobulin-like domain, IPR003598:Immunoglobulin subtype 2, IPR013162:CD80-like, immunoglobulin C2-set, IPR003961:Fibronectin type III, IPR013783:Immunoglobulin-like fold, IPR003599:Immunoglobulin subtype" CG34114 27-Aug-18 DroID_v2018_08 "Drer\hmcn2, Drer\nphs1" - - Xtro\nphs1 Mmus\Nphs1 "Hsap\MERTK, Hsap\NPHS1, Hsap\PSG1" viable FBgn0027129 l(3)E3 lethal (3) E3 http://flybase.org/reports/FBgn0027129 - gene - - - l(3)E3 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0019912 Ypf1a Yolk protein factor 1a http://flybase.org/reports/FBgn0019912 - gene DNA binding ; GO:0003677 | contributes_to inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from direct assay - Ku70:Ku80 complex ; GO:0043564 | inferred from direct assay "p86, YPF1alpha, YPF1, Ypf1a" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0043054 Ivk\gag Ivk element gag http://flybase.org/reports/FBgn0043054 transposable_element_gene - - - "You\gag, Ivk\gag" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0014955 ealk easterlike http://flybase.org/reports/FBgn0014955 - gene - - - "elk, ealk" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065588 l(2)SH0908 lethal (2) SH0908 http://flybase.org/reports/FBgn0065588 gene - - - "l(2)SH0908, l(2)SH2 0908" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0052303 tRNA:Cys-GCA-3-1 transfer RNA:Cysteine-GCA 3-1 http://flybase.org/reports/FBgn0052303 tRNA_gene UGC codon-amino acid adaptor activity ; GO:0033414 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033414 cytosol ; GO:0005829 | inferred by curator from GO:0033414 "AE002584.trna13-CysGCA, tRNA:C:GCA:AE002584-b, CR32303, chr3L.trna13-CysGCA, tRNA:Cys-GCA-3-1, tRNA:CR32303, tRNA-Cys-GCA-3-1, UGC" - CR32303 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0070006 BG01515 BG01515 http://flybase.org/reports/FBgn0070006 gene - - - BG01515 - - 27-Aug-18 DroID_v2018_08 - - - - - - stress response defective FBgn0085199 CG34170 - http://flybase.org/reports/FBgn0085199 protein_coding_gene - - - CG34170 - CG34170 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004962 l(1)17Ca lethal (1) 17Ca http://flybase.org/reports/FBgn0004962 - gene - - - "T13, l(1)17Ca" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,some die during immature adult stage" FBgn0035569 CG15876 - http://flybase.org/reports/FBgn0035569 protein_coding_gene - regulation of localization ; GO:0032879 | inferred from sequence or structural similarity with halo - "HL3, CG15876" IPR007970:Protein of unknown function DUF733 CG15876 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0005748 l(1)TK243 lethal (1) TK243 http://flybase.org/reports/FBgn0005748 - gene - - - "l243, l(1)TK243" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" "lamina,eye" FBgn0010024 E(Dl)D72 Enhancer of Delta D72 http://flybase.org/reports/FBgn0010024 - gene - - - E(Dl)D72 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0003176 Plexate Plexate http://flybase.org/reports/FBgn0003176 - gene - - - "Px, Plexate" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0026533 Dek Dek http://flybase.org/reports/FBgn0026533 "FBgn0010567, FBgn0021980, FBgn0025829, FBgn0046410, FBgn0046411, FBgn0046412" protein_coding_gene histone binding ; GO:0042393 | inferred from biological aspect of ancestor with PANTHER:PTN000336336 chromatin binding ; GO:0003682 | inferred from biological aspect of ancestor with PANTHER:PTN000336336 regulation of double-strand break repair ; GO:2000779 | inferred from biological aspect of ancestor with PANTHER:PTN000336336 chromatin remodeling ; GO:0006338 | inferred from biological aspect of ancestor with PANTHER:PTN000336336 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN000336336 nucleoplasm ; GO:0005654 | inferred from direct assay "DEK, CG593, CG5935, l(2)04154, l(2)k09907, dDEK, EG:EG0003.6, anon-WO0172774.194, anon-WO0172774.192, anon-WO0172774.191, Dek, dek, lincRNA.S2954" "IPR003034:SAP domain, IPR014876:DEK, C-terminal" CG5935 27-Aug-18 DroID_v2018_08 Drer\dek - - Xtro\dek Mmus\Dek Hsap\DEK

"viable,lethal,recessive,fertile,male limited,long lived,temperature response defective,female limited,gravitaxis defective" DRSC07418 IE -1.933559469 -1.068475533 -3.017916871 -4.1066307 1.11703303 0.118157197 FBgn0267727 Pen Pendulin http://flybase.org/reports/FBgn0267727 protein_coding_gene nuclear localization sequence binding ; GO:0008139 | inferred from biological aspect of ancestor with PANTHER:PTN001153158 protein transporter activity ; GO:0008565 | inferred from biological aspect of ancestor with PANTHER:PTN001153158 lymph gland development ; GO:0048542 | inferred from mutant phenotype sperm individualization ; GO:0007291 | inferred from mutant phenotype gravitaxis ; GO:0042332 | inferred from mutant phenotype centrosome duplication ; GO:0051298 | inferred from mutant phenotype female germline ring canal formation ; GO:0007301 | inferred from mutant phenotype NLS-bearing protein import into nucleus ; GO:0006607 | inferred from mutant phenotype nuclear pore ; GO:0005643 | inferred from biological aspect of ancestor with PANTHER:PTN001153158 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN001153158 cytoplasm ; GO:0005737 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from biological aspect of ancestor with PANTHER:PTN001153158 nucleus ; GO:0005634 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay "imp-alpha2, l(2)k06324, Pen, CG4799, imp alpha2, alpha2, Imp-alpha2, Kap-alpha2, oho-31, bs29g06.y1, importin alpha2/pendulin, Kap alpha2, oho31, Dimp-alpha2, 2.1, alpha2A-Kap, OHO31, DPend, Oho31, pen-2, pen, l(2)144/1, l(2)k14401, anon-WO0140519.258, IMPalpha2, Kpna2, Rch1, impalpha2, Dalpha2, alphaKap2" "IPR000225:Armadillo, IPR002652:Importin-alpha, importin-beta-binding domain, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold, IPR024931:Importin subunit alpha, IPR032413:Atypical Arm repeat" CG4799 27-Aug-18 DroID_v2018_08 "Drer\kpna5, Drer\kpna1, Drer\kpna2, Drer\kpna3, Drer\spag6, Drer\kpna6, Drer\kpna7" Scer\SRP1 "Cele\ima-2, Cele\ima-3" "Xtro\armc3, Xtro\kpna2, Xtro\spag6, Xtro\kpna3, Xtro\kpna6, Xtro\kpna7, Xtro\kpna1, Xtro\kpna4" "Mmus\Kpna6, Mmus\Kpna1, Mmus\Kpna4, Mmus\Kpna7, Mmus\Spag6, Mmus\Spag6l, Mmus\Kpna2, Mmus\Kpna3" "Hsap\KPNA4, Hsap\KPNA7, Hsap\KPNA5, Hsap\KPNA1, Hsap\KPNA3, Hsap\KPNA2, Hsap\SPAG6, Hsap\KPNA6" " embryonic stage | early , adult stage , embryonic stage | stage >12 , larval stage | third instar , embryonic stage | gastrula , embryonic stage | embryonic cycle 10-13 , embryonic stage | extended germ band , embryonic stage | 0-2 hr , embryonic stage -- adult stage " " ventral nerve cord

, lymph gland

,organism | segmentally repeated , larval brain | restricted

, embryonic brain | restricted

, pole cell

, ventral nerve cord primordium

, imaginal disc

,

ubiquitous , neuroblast

, ring gland

" " embryonic stage -- adult stage , embryonic stage && larval stage && adult stage " FBgn0044102 E(rst)C463 E(rst)C463 http://flybase.org/reports/FBgn0044102 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "C463, E(rst)C463" - - 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0044500 DTD44.3 DTD44.3 http://flybase.org/reports/FBgn0044500 gene - - - DTD44.3 - - 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0265078 lncRNA:CR44189 - http://flybase.org/reports/FBgn0265078 non_protein_coding_gene - - - "CR44189, lincRNA.197" - CR44189 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264523 ff14 - http://flybase.org/reports/FBgn0264523 gene - - - ff14 - - 27-Aug-18 DroID_v2018_08 - - - - - - "meiotic cell cycle defective,male" spermatid FBgn0061507 l(2)24Ac lethal (2) 24Ac http://flybase.org/reports/FBgn0061507 gene - - - l(2)24Ac - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0060348 l(3)S142814b lethal (3) S142814b http://flybase.org/reports/FBgn0060348 gene - - - "1428/14, l(3)S142814b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0262549 Mod(GMroX1)B - http://flybase.org/reports/FBgn0262549 gene - - - Mod(GMroX1)B - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,female,recessive,male" FBgn0027196 l(2)32e lethal (2) 32e http://flybase.org/reports/FBgn0027196 - gene - - - "l[32e], l(2)32e" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0032216 Usp14 Ubiquitin specific protease 14 http://flybase.org/reports/FBgn0032216 protein_coding_gene thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from sequence or structural similarity with HGNC:12612 ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from electronic annotation with InterPro:IPR018200 protein ubiquitination ; GO:0016567 | inferred from mutant phenotype protein deubiquitination ; GO:0016579 | inferred from sequence or structural similarity with HGNC:12612 microtubule associated complex ; GO:0005875 | inferred from direct assay "CG5384, DmUsp14, Ubp6p, Usp14, Q9VKZ8" "IPR001394:Peptidase C19, ubiquitin carboxyl-terminal hydrolase, IPR018200:Ubiquitin specific protease, conserved site, IPR028889:Ubiquitin specific protease domain, IPR029071:Ubiquitin-related domain" CG5384 27-Aug-18 DroID_v2018_08 "Drer\ublcp1, Drer\ubfd1, Drer\usp19, Drer\usp14" "Scer\UBP2, Scer\UBP6" Cele\usp-14 "Xtro\usp14, Xtro\ublcp1" "Mmus\Usp14, Mmus\Ublcp1, Mmus\Ubfd1, Mmus\Usp19" "Hsap\USP19, Hsap\UBLCP1, Hsap\UBFD1, Hsap\USP14" "viable,fertile,locomotor behavior defective,short lived" FBgn0051228 tRNA:Pro-TGG-1-5 transfer RNA:Proline-TGG 1-5 http://flybase.org/reports/FBgn0051228 tRNA_gene CCA codon-amino acid adaptor activity ; GO:0033423 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033423 cytosol ; GO:0005829 | inferred by curator from GO:0033423 "AE002708.trna42-ProTGG, tRNA:P:TGG:AE002708-d, CR31228, chr3R.trna48-ProTGG, tRNA-Pro-TGG-1-5, tRNA:Pro-TGG-1-5, tRNA:CR31228, CCA" - CR31228 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0022096 l(2)k07215 lethal (2) k07215 http://flybase.org/reports/FBgn0022096 - gene - - - l(2)k07215 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0260253 GSd334 - http://flybase.org/reports/FBgn0260253 gene - - - GSd334 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0033799 GLaz Glial Lazarillo http://flybase.org/reports/FBgn0033799 protein_coding_gene - cellular response to oxidative stress ; GO:0034599 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype cellular response to starvation ; GO:0009267 | inferred from mutant phenotype lipid catabolic process ; GO:0016042 | inferred from genetic interaction with fh cellular response to oxidative stress ; GO:0034599 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay "GLaz, CG4604, DGLaz" "IPR000566:Lipocalin/cytosolic fatty-acid binding domain, IPR012674:Calycin, IPR022271:Lipocalin, ApoD type" CG4604 27-Aug-18 DroID_v2018_08 "Drer\apoda.2, Drer\apoda.1, Drer\apodb" - Cele\lpr-4 - Mmus\Apod Hsap\APOD "viable,fertile,stress response defective,short lived,locomotor behavior defective,increased cell death,chemical sensitive,long lived,heat sensitive,hyperactive" "adult brain,adult nervous system,adult fat body" FBgn0040388 boi brother of ihog http://flybase.org/reports/FBgn0040388 protein_coding_gene hedgehog family protein binding ; GO:0097108 | inferred from electronic annotation with InterPro:IPR032988 cuticle pattern formation ; GO:0035017 | inferred from genetic interaction with ihog wing disc pattern formation ; GO:0035222 | inferred from genetic interaction with ihog smoothened signaling pathway ; GO:0007224 | inferred from mutant phenotype compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from genetic interaction with ihog regulation of smoothened signaling pathway ; GO:0008589 | inferred from genetic interaction with ihog positive regulation of cell proliferation ; GO:0008284 | inferred from mutant phenotype Notch signaling pathway ; GO:0007219 | inferred from genetic interaction with Dl imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from genetic interaction with ihog integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR032988 cell surface ; GO:0009986 | colocalizes_with inferred from direct assay "CT23737, EG:BACH59J11.2, CG7894, CG13756, CT33235, boi, CG32796, Boi" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR003961:Fibronectin type III, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR032988:Interference hedgehog" CG32796 27-Aug-18 DroID_v2018_08 "Drer\boc, Drer\cdon" - - "Xtro\cdon, Xtro\boc" "Mmus\Cdon, Mmus\Boc" "Hsap\BOC, Hsap\CDON" "viable,fertile,hyperplasia,visible" "follicle stem cell,wing vein,ectopic,wing blade,interfollicle cell,follicle cell" FBgn0053632 CG33632 - http://flybase.org/reports/FBgn0053632 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CR33632, CG33632" IPR010512:Protein of unknown function DUF1091 CG33632 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039240 CG3744 - http://flybase.org/reports/FBgn0039240 protein_coding_gene serine-type peptidase activity ; GO:0008236 | inferred from electronic annotation with InterPro:IPR001375 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001375, InterPro:IPR002469" - CG3744 "IPR029058:Alpha/Beta hydrolase fold, IPR001375:Peptidase S9, prolyl oligopeptidase, catalytic domain, IPR002469:Dipeptidylpeptidase IV, N-terminal domain" CG3744 27-Aug-18 DroID_v2018_08 Drer\dpp9 "Scer\DAP2, Scer\STE13" "Cele\dpf-2, Cele\dpf-1, Cele\dpf-3" "Xtro\dpp9, Xtro\dpp8" "Mmus\Dpp8, Mmus\Dpp9" "Hsap\DPP9, Hsap\DPP8" "viable,fertile" FBgn0083970 CG34134 - http://flybase.org/reports/FBgn0083970 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG8475, CG34134" - CG34134 27-Aug-18 DroID_v2018_08 "Drer\phkb, Drer\phka1a, Drer\phka1b, Drer\phka2" - - "Xtro\phkb, Xtro\phka2, Xtro\LOC100498239" "Mmus\Phkb, Mmus\Phka2, Mmus\Phka1" "Hsap\PHKA2, Hsap\PHKB, Hsap\PHKA1" FBgn0263442 asRNA:CR43465 - http://flybase.org/reports/FBgn0263442 non_protein_coding_gene - - - CR43465 - CR43465 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259635 B0426 - http://flybase.org/reports/FBgn0259635 gene - - - B0426 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" proboscis FBgn0031263 Tspo Translocator protein http://flybase.org/reports/FBgn0031263 protein_coding_gene - regulation of oxidative phosphorylation ; GO:0002082 | inferred from mutant phenotype positive regulation of apoptotic process ; GO:0043065 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR004307 mitochondrial outer membrane ; GO:0005741 | inferred from direct assay mitochondrial envelope ; GO:0005740 | inferred from sequence or structural similarity with UniProtKB:P30536 "anon-EST:Posey116, CG2789, Tspo, dTSPO, tspo" IPR004307:TspO/MBR-related protein CG2789 27-Aug-18 DroID_v2018_08 Drer\tspo - Cele\C41G7.9 Xtro\tspo "Mmus\Tspo, Mmus\Tspo2" "Hsap\TSPO2, Hsap\TSPO" viable FBgn0025476 pogo\T pogo transposase http://flybase.org/reports/FBgn0025476 - transposable_element_gene - - - pogo\T - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0043581 MESK1 Misexpression Suppressor of KDN 1 http://flybase.org/reports/FBgn0043581 gene - positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with ksr inferred from genetic interaction with Ras85D - MESK1 - - 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0003359 sesA stress-sensitive A http://flybase.org/reports/FBgn0003359 - gene molecular_function ; GO:0003674 | no biological data available flight behavior ; GO:0007629 | inferred from mutant phenotype response to mechanical stimulus ; GO:0009612 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available sesA - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,heat sensitive,bang sensitive,flight defective,behavior defective" FBgn0283510 Pal1 Peptidyl-alpha-hydroxyglycine-alpha-amidating lyase 1 http://flybase.org/reports/FBgn0283510 protein_coding_gene peptidylamidoglycolate lyase activity ; GO:0004598 | inferred from direct assay peptide metabolic process ; GO:0006518 | inferred from electronic annotation with InterPro:IPR000720 regulation of imaginal disc-derived wing size ; GO:0044719 | inferred from mutant phenotype courtship behavior ; GO:0007619 | non-traceable author statement membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR000720 neuronal cell body ; GO:0043025 | inferred from direct assay "ta, anon-WO0149856.3, Pal1, CG12130, PAL1, dPAL1, DPAL1" "IPR000720:Peptidylglycine alpha-hydroxylating monooxygenase/peptidyl-hydroxyglycine alpha-amidating lyase, IPR013017:NHL repeat, subgroup, IPR011042:Six-bladed beta-propeller, TolB-like, IPR001258:NHL repeat" CG12130 27-Aug-18 DroID_v2018_08 Drer\pam - "Cele\pgal-1, Cele\pamn-1, Cele\nhl-1, Cele\pghm-1" Xtro\pam "Mmus\Pam, Mmus\Nhlrc3" "Hsap\PAM, Hsap\NHLRC3" "viable,reduced,visible,female fertile,male sterile,dominant,behavior defective,poor,lethal,recessive" "wing,wing vein" FBgn0035022 CG11413 - http://flybase.org/reports/FBgn0035022 protein_coding_gene - - - "CT31865, BcDNA:RH33060, CG11413" - CG11413 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" FBgn0069185 mcl(2)Z0193 mcl(2)Z0193 http://flybase.org/reports/FBgn0069185 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(2)Z0193 - - 27-Aug-18 DroID_v2018_08 - - - - - - male fertile FBgn0264297 CG43775 - http://flybase.org/reports/FBgn0264297 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available extracellular region ; GO:0005576 | inferred from sequence model "CG43775, CG13569, CG13569-1" "IPR014044:CAP domain, IPR001283:Cysteine-rich secretory protein, allergen V5/Tpx-1-related" CG43775 27-Aug-18 DroID_v2018_08 "Drer\crispld1a, Drer\crispld2, Drer\r3hdml, Drer\LOC100536500, Drer\pi15b, Drer\glipr1b, Drer\glipr2l, Drer\crispld1b, Drer\glipr2, Drer\pi15a" "Scer\PRY3, Scer\PRY1, Scer\PRY2" "Cele\lon-1, Cele\scl-23, Cele\scl-10, Cele\vap-1, Cele\vap-2" "Xtro\crisp3, Xtro\glipr2, Xtro\crisp2, Xtro\MGC108118, Xtro\r3hdml, Xtro\crisp1, Xtro\crispld2" "Mmus\Clec18a, Mmus\Crispld2, Mmus\Glipr1l2, Mmus\Pi16, Mmus\Crisp3, Mmus\Crisp1, Mmus\R3hdml, Mmus\Crisp4, Mmus\Crisp2, Mmus\Glipr1, Mmus\Glipr2, Mmus\Glipr1l1, Mmus\Crispld1, Mmus\Pi15" "Hsap\CLEC18B, Hsap\PI15, Hsap\GLIPR2, Hsap\GLIPR1L2, Hsap\CLEC18C, Hsap\CRISPLD2, Hsap\R3HDML, Hsap\CRISP1, Hsap\GLIPR1L1, Hsap\PI16, Hsap\CLEC18A, Hsap\CRISPLD1, Hsap\GLIPR1, Hsap\CRISP2" viable FBgn0065802 l(2)SH0404 lethal (2) SH0404 http://flybase.org/reports/FBgn0065802 gene - - - l(2)SH0404 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0003934 snRNA:U5:23D small nuclear RNA U5 at 23DE http://flybase.org/reports/FBgn0003934 FBgn0003932 snRNA_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity" U5 snRNP ; GO:0005682 | inferred from sequence or structural similarity "U5, U5-23D, snRNA[[3]], K2, dU5, snRNA:U5:23DE, snRNA:U5, snRNA4, snRNA3, U5snRNA23DE, CR32999, U5snRNA, snRNA:U5:23D, U5:23D, U5 snRNA, U5 snRNA 23D" - CR32999 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266072 lncRNA:CR44825 - http://flybase.org/reports/FBgn0266072 non_protein_coding_gene - - - CR44825 - CR44825 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065912 l(2)SH0177 lethal (2) SH0177 http://flybase.org/reports/FBgn0065912 gene - - - "l(2)SH0177, l(2)SH2 0177" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0035715 CG10103 - http://flybase.org/reports/FBgn0035715 protein_coding_gene molecular_function ; GO:0003674 | no biological data available protein transport ; GO:0015031 | inferred from electronic annotation with InterPro:IPR005061 endosome transport via multivesicular body sorting pathway ; GO:0032509 | inferred from sequence or structural similarity with SGD:S000005209 endosome ; GO:0005768 | inferred from sequence or structural similarity with SGD:S000005209 CG10103 IPR005061:Vacuolar protein sorting-associated protein Ist1 CG10103 27-Aug-18 DroID_v2018_08 Drer\ist1 Scer\IST1 Cele\istr-1 "Xtro\LOC100216037, Xtro\ist1" Mmus\Ist1 Hsap\IST1 viable FBgn0265487 mbl muscleblind http://flybase.org/reports/FBgn0265487 protein_coding_gene metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR000571 nucleic acid binding ; GO:0003676 | non-traceable author statement DNA binding ; GO:0003677 | traceable author statement "apoptotic process ; GO:0006915 | inferred from direct assay regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | traceable author statement regulation of gene expression ; GO:0010468 | inferred from mutant phenotype muscle organ development ; GO:0007517 | inferred from mutant phenotype regulation of female receptivity ; GO:0045924 | inferred from mutant phenotype rhabdomere development ; GO:0042052 | inferred from mutant phenotype eye development ; GO:0001654 | inferred from mutant phenotype compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from mutant phenotype muscle cell cellular homeostasis ; GO:0046716 | inferred from mutant phenotype inferred from genetic interaction with Dg inferred from genetic interaction with Dys embryo development ; GO:0009790 | inferred from mutant phenotype regulation of female receptivity ; GO:0045924 | non-traceable author statement imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype somatic muscle development ; GO:0007525 | traceable author statement compound eye photoreceptor cell differentiation ; GO:0001751 | traceable author statement" cytoplasm ; GO:0005737 | inferred from direct assay H zone ; GO:0031673 | inferred from direct assay Z disc ; GO:0030018 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay "mbl, Mbl, mbn, chst, mm, CG14477, n(2)k07110, l(2)k01212, l(2)01038, l(2)k05507, CG10941, CG33197, chaste, cht, BG01127, mb1" "IPR000571:Zinc finger, CCCH-type, IPR015943:WD40/YVTN repeat-like-containing domain" CG33197 27-Aug-18 DroID_v2018_08 "Drer\mbnl1, Drer\mbnl3, Drer\zc3h10, Drer\mbnl2" - "Cele\Y53G8AR.9, Cele\mbl-1" "Xtro\mbnl2, Xtro\zc3h10, Xtro\mbnl1, Xtro\mbnl3" "Mmus\Zc3h10, Mmus\Mbnl2, Mmus\Mbnl1, Mmus\Mbnl3" "Hsap\MBNL3, Hsap\MBNL2, Hsap\MBNL1, Hsap\ZC3H10" larval stage eye disc

larval stage " early ommatidial precursor cluster

, imaginal disc

" FBgn0039478 Nep5 Neprilysin 5 http://flybase.org/reports/FBgn0039478 protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR018497 metallopeptidase activity ; GO:0008237 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR008753, InterPro:IPR018497 proteolysis ; GO:0006508 | inferred from sequence model" integral component of membrane ; GO:0016021 | inferred from sequence model "CG6265, Nep5, DmeNEP5, NEP5, nep5" "IPR000718:Peptidase M13, IPR008753:Peptidase M13, N-terminal domain, IPR030082:Neprilysin-21, IPR024079:Metallopeptidase, catalytic domain, IPR018497:Peptidase M13, C-terminal domain" CG6265 27-Aug-18 DroID_v2018_08 "Drer\ece1, Drer\phex, Drer\mmel1, Drer\ece2b" - "Cele\nep-22, Cele\nep-4, Cele\nep-15, Cele\nep-19, Cele\nep-2, Cele\nep-25" "Xtro\ece2, Xtro\mmel1, Xtro\ecel1, Xtro\ece1" "Mmus\Ece2, Mmus\Mme, Mmus\Kel, Mmus\Mmel1, Mmus\Ecel1, Mmus\Phex, Mmus\Ece1" "Hsap\ECEL1, Hsap\MMEL1, Hsap\KEL, Hsap\PHEX, Hsap\ECE1, Hsap\ECE2, Hsap\MME" viable FBgn0028626 l(2)01034 lethal (2) 01034 http://flybase.org/reports/FBgn0028626 gene - - - l(2)01034 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0028283 l(1)G0414 lethal (1) G0414 http://flybase.org/reports/FBgn0028283 gene - - - l(1)G0414 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0262698 Su(VGlut)B51 - http://flybase.org/reports/FBgn0262698 gene - - - "Su(VGlut)B51, B51" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031606 CG15439 - http://flybase.org/reports/FBgn0031606 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841, InterPro:IPR001965" lateral inhibition ; GO:0046331 | inferred from mutant phenotype - CG15439 "IPR001965:Zinc finger, PHD-type, IPR011011:Zinc finger, FYVE/PHD-type, IPR019786:Zinc finger, PHD-type, conserved site, IPR019787:Zinc finger, PHD-finger, IPR034732:Extended PHD (ePHD) domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG15439 27-Aug-18 DroID_v2018_08 Drer\phf14 Scer\SNT2 Cele\phf-14 Xtro\phf14 Mmus\Phf14 Hsap\PHF14 "viable,fertile,partially lethal - majority die,visible" "chaeta,supernumerary,mesothoracic tergum" DRSC00453 K 0.131049222 -0.288534242 0.246335475 -0.938027636 -0.246309738 1.757252071 FBgn0016967 w::Dmau\w w::Dmau\w http://flybase.org/reports/FBgn0016967 - engineered_fusion_gene - - - w::Dmau\w - - 27-Aug-18 DroID_v2018_08 - - - - - - "eye color defective,visible" pigment cell FBgn0032416 Gr33a Gustatory receptor 33a http://flybase.org/reports/FBgn0032416 protein_coding_gene taste receptor activity ; GO:0008527 | non-traceable author statement sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 male courtship behavior ; GO:0008049 | inferred from mutant phenotype sensory perception of taste ; GO:0050909 | inferred from mutant phenotype sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 male mating behavior ; GO:0060179 | inferred from mutant phenotype sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of taste ; GO:0050909 | non-traceable author statement integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 dendrite ; GO:0030425 | inferred from direct assay cell body ; GO:0044297 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 integral component of membrane ; GO:0016021 | non-traceable author statement axon ; GO:0030424 | inferred from direct assay "CG17213, Gr33C1, Gr33a, GR33a" IPR013604:7TM chemoreceptor CG17213 27-Aug-18 DroID_v2018_08 - - "Cele\lite-1, Cele\gur-3" - - - "courtship behavior defective,male,neurophysiology defective,taste perception defective,chemosensitive behavior defective,viable" labellar taste bristle FBgn0263337 lncRNA:CR43418 - http://flybase.org/reports/FBgn0263337 non_protein_coding_gene - - - CR43418 - CR43418 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0013251 E(var)3-5 E(var)3-5 http://flybase.org/reports/FBgn0013251 - gene - - - "E-var(3)5, E(var)3-5" - - 27-Aug-18 DroID_v2018_08 - - - - - - "suppressor of variegation,dominant,enhancer of variegation" FBgn0030624 CG9106 - http://flybase.org/reports/FBgn0030624 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG9106 - CG9106 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060545 l(3)S098911b lethal (3) S098911b http://flybase.org/reports/FBgn0060545 gene - - - "0989/11, l(3)S098911b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0037039 CG10587 - http://flybase.org/reports/FBgn0037039 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 extracellular space ; GO:0005615 | inferred from direct assay "SP167, CG10587" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site" CG10587 27-Aug-18 DroID_v2018_08 Drer\tmprss2 - "Cele\try-5, Cele\try-1, Cele\svh-1" - Mmus\Gzma Hsap\GZMA "viable,fertile" FBgn0040671 CG12569 - http://flybase.org/reports/FBgn0040671 protein_coding_gene - - - CG12569 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038565 CG7794 - http://flybase.org/reports/FBgn0038565 protein_coding_gene "structural constituent of cytoskeleton ; GO:0005200 | inferred from electronic annotation with InterPro:IPR002452 GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR002452, InterPro:IPR008280 GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR003008, InterPro:IPR008280 structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity" "microtubule-based process ; GO:0007017 | inferred from electronic annotation with InterPro:IPR000217, InterPro:IPR002452" "microtubule ; GO:0005874 | inferred from electronic annotation with InterPro:IPR000217, InterPro:IPR002452 microtubule ; GO:0005874 | inferred from sequence or structural similarity" "anon-WO0140519.191, CG7794, Tub1B" "IPR000217:Tubulin, IPR002452:Alpha tubulin, IPR003008:Tubulin/FtsZ, GTPase domain, IPR008280:Tubulin/FtsZ, C-terminal, IPR018316:Tubulin/FtsZ, 2-layer sandwich domain" CG7794 27-Aug-18 DroID_v2018_08 "Drer\tuba8l, Drer\tuba1b, Drer\tuba2, Drer\si:ch211-114n24.6, Drer\tuba4l, Drer\tuba8l2, Drer\tuba1a, Drer\tuba7l, Drer\tuba1c, Drer\si:ch73-199e17.1" "Scer\TUB3, Scer\TUB1" "Cele\mec-12, Cele\tba-4, Cele\tba-9, Cele\tba-6, Cele\tba-5, Cele\tba-8" "Xtro\tuba4a, Xtro\tuba3c, Xtro\tuba4, Xtro\tuba1c, Xtro\tuba3e, Xtro\tubal3, Xtro\tuba1a, Xtro\tuba8, Xtro\tuba4b" "Mmus\Tuba3b, Mmus\Tuba1c, Mmus\Tuba1b, Mmus\Tuba1a, Mmus\Tuba3a, Mmus\Tuba4a, Mmus\Tubal3, Mmus\Tuba8" "Hsap\TUBA4A, Hsap\TUBA3E, Hsap\TUBA1B, Hsap\TUBA8, Hsap\TUBA1C, Hsap\TUBA1A, Hsap\TUBAL3, Hsap\TUBA3C, Hsap\TUBA3D" viable FBgn0065602 l(2)SH0865 lethal (2) SH0865 http://flybase.org/reports/FBgn0065602 gene - - - "l(2)SH0865, l(2)SH2 0865" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0000959 fs(2)E6 female sterile (2) E6 http://flybase.org/reports/FBgn0000959 - gene - - - "fs2.6, fs(2)E6" - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive" egg FBgn0262464 mir-6-1 mir-6-1 stem loop http://flybase.org/reports/FBgn0262464 miRNA_gene - negative regulation of cell death ; GO:0060548 | inferred from mutant phenotype - "mir-6-1, mir-6, 6-1, Dme-miR-6, miR-6-1, CR43047, miR-6, miR6-1, CR33004, dme-mir-6-1" - CR43047 27-Aug-18 DroID_v2018_08 - - - - - - " embryonic stage , larval stage | first instar " visible chaeta FBgn0267250 l(3)j13C8 - http://flybase.org/reports/FBgn0267250 gene - - - l(3)j13C8 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0086448 PIG-Q Phosphatidylinositol glycan anchor biosynthesis class Q http://flybase.org/reports/FBgn0086448 protein_coding_gene phosphatidylinositol N-acetylglucosaminyltransferase activity ; GO:0017176 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000481757 GPI anchor biosynthetic process ; GO:0006506 | inferred from sequence or structural similarity with HGNC:14135 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR007720 endoplasmic reticulum membrane ; GO:0005789 | inferred from sequence or structural similarity with HGNC:14135 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex ; GO:0000506 | inferred from biological aspect of ancestor with PANTHER:PTN000481757 "l(1)14Ca, Dm_CAC10056/216-441, dGpi1, CG32578, l(1)i19, l(1)i19e, l(1)19-134, l(1)14Cd, i19e, PIG-Q, Gpi1" IPR007720:N-acetylglucosaminyl transferase component CG32578 27-Aug-18 DroID_v2018_08 Drer\pigq Scer\GPI1 Cele\F01G4.5 Xtro\pigq Mmus\Pigq Hsap\PIGQ FBgn0008639 66Dem 66Dem http://flybase.org/reports/FBgn0008639 - gene - - - 66Dem - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266466 cashew - http://flybase.org/reports/FBgn0266466 gene - - - cashew - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,cell polarity defective,germline clone" "egg chamber,germline clone,oocyte,centrosome | germline clone" FBgn0046846 dec-1::Dvir\dec-1 dec-1::Dvir\dec-1 http://flybase.org/reports/FBgn0046846 engineered_fusion_gene - - - dec-1::Dvir\dec-1 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004794 war warbler http://flybase.org/reports/FBgn0004794 - gene molecular_function ; GO:0003674 | no biological data available ovarian nurse cell to oocyte transport ; GO:0007300 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available war - - 27-Aug-18 DroID_v2018_08 - - - - - - female sterile FBgn0030137 CG15317 - http://flybase.org/reports/FBgn0030137 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15317 - CG15317 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000280 Cec-Psi1 Cecropin pseudogene 1 http://flybase.org/reports/FBgn0000280 - pseudogene_attribute - - - "CecPsi1, cec-Psi1, CR32926, Cec-Psi1" - CR32926 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0015985 l(2)PC4-N lethal (2) PC4-N http://flybase.org/reports/FBgn0015985 - gene - - - "fs(2)PC4-N, l(2)PC4-N" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,maternal effect,recessive" FBgn0036117 CG6321 - http://flybase.org/reports/FBgn0036117 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR015421, InterPro:IPR015422 pyridoxal phosphate binding ; GO:0030170 | inferred from electronic annotation with InterPro:IPR004839" biosynthetic process ; GO:0009058 | inferred from electronic annotation with InterPro:IPR004839 - CG6321 "IPR004839:Aminotransferase, class I/classII, IPR015421:Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015422:Pyridoxal phosphate-dependent transferase, subdomain 2, IPR015424:Pyridoxal phosphate-dependent transferase" CG6321 27-Aug-18 DroID_v2018_08 Drer\aadat "Scer\ARO9, Scer\YER152C, Scer\ARO8" - Xtro\aadat Mmus\Aadat Hsap\AADAT "viable,fertile" FBgn0262961 CG43272 - http://flybase.org/reports/FBgn0262961 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43272, lincRNA.337" - CG43272 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051824 CR31824 - http://flybase.org/reports/FBgn0051824 pseudogene_attribute - - - "CG18629, CR31824, CG31824" - CR31824 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034943 Fmo-1 Flavin-containing monooxygenase 1 http://flybase.org/reports/FBgn0034943 protein_coding_gene "N,N-dimethylaniline monooxygenase activity ; GO:0004499 | inferred from electronic annotation with InterPro:IPR000960, InterPro:IPR020946 NADP binding ; GO:0050661 | inferred from electronic annotation with InterPro:IPR000960, InterPro:IPR020946 flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR000960, InterPro:IPR020946 monooxygenase activity ; GO:0004497 | inferred from direct assay" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000960, InterPro:IPR020946, InterPro:IPR023753" intracellular membrane-bounded organelle ; GO:0043231 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "DmFMO-1, FMO-1, CG3006, Fmo-1" "IPR000960:Flavin monooxygenase FMO, IPR020946:Flavin monooxygenase-like, IPR023753:FAD/NAD(P)-binding domain" CG3006 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-239i20.4, Drer\LOC793236, Drer\si:dkey-239i20.2, Drer\fmo5, Drer\foxred2, Drer\zgc:77439" Scer\FMO1 "Cele\fmo-3, Cele\fmo-5, Cele\fmo-1, Cele\fmo-2, Cele\fmo-4, Cele\C46H11.2, Cele\C01H6.4" "Xtro\fmo1, Xtro\LOC100490281, Xtro\foxred2, Xtro\fmo5, Xtro\fmo2, Xtro\fmo3" "Mmus\Fmo9, Mmus\Fmo2, Mmus\Foxred2, Mmus\Fmo1, Mmus\Fmo5, Mmus\Fmo6, Mmus\Fmo3, Mmus\Gm4847, Mmus\Gm4846, Mmus\Fmo4" "Hsap\FOXRED2, Hsap\FMO5, Hsap\FMO4, Hsap\FMO1, Hsap\FMO3, Hsap\FMO2" "partially lethal - majority die,some die during pupal stage" FBgn0051773 CG31773 - http://flybase.org/reports/FBgn0051773 protein_coding_gene "tetrahydrofolylpolyglutamate synthase activity ; GO:0004326 | inferred from electronic annotation with InterPro:IPR001645, InterPro:IPR023600 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001645, InterPro:IPR013221, InterPro:IPR023600" "folic acid-containing compound biosynthetic process ; GO:0009396 | inferred from electronic annotation with InterPro:IPR001645, InterPro:IPR023600" - "CG3390, CG31773" "IPR001645:Folylpolyglutamate synthetase, IPR013221:Mur ligase, central, IPR023600:Folylpolyglutamate synthase, eukaryota" CG31773 27-Aug-18 DroID_v2018_08 "Drer\nphs1, Drer\fpgs" "Scer\RMA1, Scer\FOL3, Scer\MET7" Cele\F25B5.6 "Xtro\fpgs, Xtro\nphs1" "Mmus\Fpgs, Mmus\Nphs1" "Hsap\NPHS1, Hsap\FPGS" DRSC00600 IK 1.751746241 0.045667974 0.791412586 0.738587127 0.297718222 1.563776233 FBgn0083093 curta curta http://flybase.org/reports/FBgn0083093 gene - - - curta - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0050268 CG30268 - http://flybase.org/reports/FBgn0050268 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR023753 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR023753 - "CG13520, CG30268" "IPR032151:Cilia- and flagella-associated protein 61, N-terminal domain, IPR023753:FAD/NAD(P)-binding domain" CG30268 27-Aug-18 DroID_v2018_08 - - - Xtro\cfap61 Mmus\Cfap61 Hsap\CFAP61 viable FBgn0020585 anon-57Cl anon-57Cl http://flybase.org/reports/FBgn0020585 - gene - - - anon-57Cl - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037215 beta-Man beta-Mannosidase http://flybase.org/reports/FBgn0037215 protein_coding_gene "hydrolase activity, hydrolyzing O-glycosyl compounds ; GO:0004553 | inferred from electronic annotation with InterPro:IPR006102, InterPro:IPR013812" "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR006102, InterPro:IPR013781, InterPro:IPR013812" - "CG12583, CG12582, beta-Man" "IPR008979:Galactose-binding domain-like, IPR006102:Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich, IPR017853:Glycoside hydrolase superfamily, IPR013783:Immunoglobulin-like fold" CG12582 27-Aug-18 DroID_v2018_08 Drer\manba - Cele\C33G3.4 Xtro\manba Mmus\Manba Hsap\MANBA viable FBgn0053368 5SrRNA:CR33368 5SrRNA:CR33368 http://flybase.org/reports/FBgn0053368 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33368, 5SrRNA:CR33368" - CR33368 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0020426 HLH44A HLH44A http://flybase.org/reports/FBgn0020426 - gene - - - "44A, HLH44A" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060740 l(3)S066619b lethal (3) S066619b http://flybase.org/reports/FBgn0060740 gene - - - "0666/19, l(3)S066619b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0034099 CG15708 - http://flybase.org/reports/FBgn0034099 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR003656 - - CG15708 "IPR006629:LPS-induced tumour necrosis factor alpha factor, IPR003656:Zinc finger, BED-type" CG15708 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0262751 Mst77Y-2 Male-specific transcript 77Y 2 http://flybase.org/reports/FBgn0262751 nuclear_gene molecular_function ; GO:0003674 | no biological data available "spermatogenesis, exchange of chromosomal proteins ; GO:0035093 | inferred from sequence or structural similarity with Mst77F" chromatin ; GO:0000785 | inferred from sequence or structural similarity with Mst77F Mst77Y-2 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030280 CG11106 - http://flybase.org/reports/FBgn0030280 protein_coding_gene - - - "BcDNA:AT24116, CG11106" - CG11106 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC19381 K 0.412976335 -0.065854499 0.080563275 -0.196760164 1.690240472 0.224836486 FBgn0001725 l(1)ESHS46 lethal (1) ESHS46 http://flybase.org/reports/FBgn0001725 - gene - - - l(1)ESHS46 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0034939 thoc5 thoc5 http://flybase.org/reports/FBgn0034939 protein_coding_gene mRNA binding ; GO:0003729 | inferred from biological aspect of ancestor with PANTHER:PTN000332618 "cell proliferation ; GO:0008283 | inferred from mutant phenotype mRNA export from nucleus ; GO:0006406 | inferred from biological aspect of ancestor with PANTHER:PTN000332618 positive regulation of DNA-templated transcription, elongation ; GO:0032786 | inferred from biological aspect of ancestor with PANTHER:PTN000332618 male meiosis ; GO:0007140 | inferred from mutant phenotype mRNA export from nucleus in response to heat stress ; GO:0031990 | inferred by curator from GO:0000347 response to heat ; GO:0009408 | inferred from mutant phenotype" "THO complex part of transcription export complex ; GO:0000445 | inferred from biological aspect of ancestor with PANTHER:PTN000332618 protein complex ; GO:0043234 | inferred from physical interaction with thoc7, Hpr1 nuclear chromosome ; GO:0000228 | colocalizes_with inferred from direct assay transcription export complex ; GO:0000346 | inferred from sequence or structural similarity with HGNC:19074 nucleolus ; GO:0005730 | colocalizes_with inferred from direct assay THO complex ; GO:0000347 | inferred from direct assay" "THOC5, CG2980, thoc5, Thoc5, garm" "IPR019163:THO complex, subunit 5" CG2980 27-Aug-18 DroID_v2018_08 Drer\thoc5 - Cele\Y32H12A.2 Xtro\thoc5 Mmus\Thoc5 Hsap\THOC5 "male sterile,recessive,female fertile,viable" "nucleolus,condensed nuclear chromosome,spermatid" FBgn0034478 CG10822 - http://flybase.org/reports/FBgn0034478 protein_coding_gene "dynein intermediate chain binding ; GO:0045505 | inferred from biological aspect of ancestor with PANTHER:PTN000081506 ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity" microtubule-based movement ; GO:0007018 | inferred from biological aspect of ancestor with PANTHER:PTN000081506 microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity dynein complex ; GO:0030286 | inferred from biological aspect of ancestor with PANTHER:PTN000081506 dynein complex ; GO:0030286 | inferred from sequence or structural similarity CG10822 IPR004942:Roadblock/LAMTOR2 domain CG10822 27-Aug-18 DroID_v2018_08 "Drer\dynlrb1, Drer\si:ch211-147k9.8" - Cele\dyrb-1 "Xtro\dynlrb2, Xtro\dynlrb1" "Mmus\Dynlrb2, Mmus\Dynlrb1" "Hsap\DYNLRB2, Hsap\DYNLRB1" "viable,body color defective" mesothoracic tergum FBgn0086284 GS8172 - http://flybase.org/reports/FBgn0086284 gene - - - "GS8172, 8172" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0023216 Parg Poly(ADP-ribose) glycohydrolase http://flybase.org/reports/FBgn0023216 - protein_coding_gene poly(ADP-ribose) glycohydrolase activity ; GO:0004649 | inferred from electronic annotation with InterPro:IPR007724 response to heat ; GO:0009408 | inferred from mutant phenotype maintenance of protein location in nucleus ; GO:0051457 | inferred from mutant phenotype female germ-line stem cell population maintenance ; GO:0036099 | inferred from mutant phenotype regulation of histone acetylation ; GO:0035065 | inferred from mutant phenotype regulation of RNA splicing ; GO:0043484 | inferred from mutant phenotype Cajal body organization ; GO:0030576 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype chromatin silencing ; GO:0006342 | inferred from mutant phenotype carbohydrate metabolic process ; GO:0005975 | inferred from mutant phenotype nucleoplasm ; GO:0005654 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "PARG, EG:114E2.1, CG2864, Parg, parg, HD10914" IPR007724:Poly(ADP-ribose) glycohydrolase CG2864 27-Aug-18 DroID_v2018_08 "Drer\parga, Drer\pargb" - "Cele\parg-2, Cele\parg-1" Xtro\parg Mmus\Parg "Hsap\BPHL, Hsap\PARG" "visible,partially lethal - majority die,cold sensitive,short lived,sterile,neuroanatomy defective,melanotic mass phenotype,lethal,partially,heat stress response defective,viable" "dorsocentral bristle,scutellar bristle,ectopic,microchaeta,wing,mesothoracic leg,neuron & nucleus & adult,oocyte,cell non-autonomous,germline clone,somatic clone,female germline stem cell,Cajal body,histone locus body,nucleolusda.G32" FBgn0266310 asRNA:CR44975 - http://flybase.org/reports/FBgn0266310 non_protein_coding_gene - - - CR44975 - CR44975 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031088 CG15322 - http://flybase.org/reports/FBgn0031088 protein_coding_gene - - - CG15322 - CG15322 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0032122 CG31883 - http://flybase.org/reports/FBgn0032122 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "CG17022, anon-WO0140519.218, CG31883" - CG31883 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0005092 fs(2)OWc4 female sterile (2) OWc4 http://flybase.org/reports/FBgn0005092 - gene - - - fs(2)OWc4 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0058343 CG40343 - http://flybase.org/reports/FBgn0058343 protein_coding_gene - - - CG40343 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267693 asRNA:CR46029 - http://flybase.org/reports/FBgn0267693 non_protein_coding_gene - - - CR46029 - CR46029 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036807 CG6893 - http://flybase.org/reports/FBgn0036807 protein_coding_gene sulfate transmembrane transporter activity ; GO:0015116 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 oxaloacetate transmembrane transporter activity ; GO:0015131 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 succinate transmembrane transporter activity ; GO:0015141 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 phosphate transmembrane transporter activity ; GO:1901677 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 antiporter activity ; GO:0015297 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 thiosulfate transmembrane transporter activity ; GO:0015117 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 malate transmembrane transporter activity ; GO:0015140 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 phosphate ion transmembrane transport ; GO:0035435 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 sulfate transport ; GO:0008272 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 oxaloacetate transport ; GO:0015729 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 thiosulfate transport ; GO:0015709 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 succinate transmembrane transport ; GO:0071422 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 mitochondrial transport ; GO:0006839 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 malate transmembrane transport ; GO:0071423 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 CG6893 "IPR018108:Mitochondrial substrate/solute carrier, IPR023395:Mitochondrial carrier domain" CG6893 27-Aug-18 DroID_v2018_08 "Drer\si:ch1073-100f3.2, Drer\slc25a10, Drer\slc25a11" Scer\DIC1 Cele\slc-25A10 "Xtro\rangrf, Xtro\slc25a10" "Mmus\Slc25a11, Mmus\Slc25a10" "Hsap\SLC25A10, Hsap\SLC25A11" viable FBgn0036784 CG5103 - http://flybase.org/reports/FBgn0036784 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR009014 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR009014 - CG5103 "IPR005474:Transketolase, N-terminal, IPR005475:Transketolase-like, pyrimidine-binding domain, IPR009014:Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II, IPR020826:Transketolase binding site, IPR029061:Thiamin diphosphate-binding fold, IPR033248:Transketolase, C-terminal domain" CG5103 27-Aug-18 DroID_v2018_08 "Drer\tktb, Drer\tkta" "Scer\TKL2, Scer\TKL1" Cele\tkt-1 "Xtro\tkt, Xtro\tktl2" "Mmus\Tktl2, Mmus\Tktl1, Mmus\Tkt" "Hsap\TKTL1, Hsap\TKT, Hsap\TKTL2" viable FBgn0052284 CG32284 - http://flybase.org/reports/FBgn0052284 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "BcDNA:LP03531, CG32284" IPR002557:Chitin binding domain CG32284 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0029716 CG3546 - http://flybase.org/reports/FBgn0029716 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG3546 - CG3546 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0264604 lncRNA:CR43953 - http://flybase.org/reports/FBgn0264604 non_protein_coding_gene - - - "CR43953, lincRNA.471" - CR43953 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0022760 Wmc2 Wee-Mik-Complementing 2 http://flybase.org/reports/FBgn0022760 - gene - - - "WMC2, Wmc2" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032994 CG17482 - http://flybase.org/reports/FBgn0032994 protein_coding_gene - - - CG17482 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001905 l(2)24Dc lethal (2) 24Dc http://flybase.org/reports/FBgn0001905 - gene - - - "jf1, l(2)jf1, l(2)24Dc" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0264359 lncRNA:CR43811 - http://flybase.org/reports/FBgn0264359 non_protein_coding_gene - - - "CR43811, lincRNA.S2724, lincRNA.305" - CR43811 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0050489 Cyp12d1-p Cyp12d1-p http://flybase.org/reports/FBgn0050489 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 response to insecticide ; GO:0017085 | inferred from mutant phenotype response to DDT ; GO:0046680 | inferred from mutant phenotype" - "Cyp12d1, 12d1, CYP12D1, 12D1, CG18240, CG30489, Cyp12d1-p, Cyp 12d1, CYP12d1-p" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG30489 27-Aug-18 DroID_v2018_08 "Drer\cyp27a7, Drer\cyp11a2, Drer\cyp27a1.2, Drer\zgc:136333, Drer\si:ch211-113j14.1, Drer\cyp11c1, Drer\si:dkey-91i10.3, Drer\cyp27c1, Drer\cyp27a1.4, Drer\cyp27b1, Drer\cyp24a1" Scer\DIT2 "Cele\cyp-37B1, Cele\ZK177.4, Cele\cyp-44A1" "Xtro\cyp11a1, Xtro\cyp27b1, Xtro\cyp24a1, Xtro\LOC100145331, Xtro\cyp27c1, Xtro\cyp27a1" "Mmus\Cyp11b1, Mmus\Cyp11b2, Mmus\Cyp24a1, Mmus\Cyp11a1, Mmus\Cyp27b1, Mmus\Cyp27a1" "Hsap\CYP27A1, Hsap\CYP11B2, Hsap\CYP11A1, Hsap\CYP27C1, Hsap\CYP24A1, Hsap\CYP11B1, Hsap\CYP27B1" chemical resistant FBgn0260245 GSd453 - http://flybase.org/reports/FBgn0260245 gene - - - GSd453 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0067780 bsl boussole http://flybase.org/reports/FBgn0067780 gene molecular_function ; GO:0003674 | no biological data available bicoid mRNA localization ; GO:0045450 | inferred from mutant phenotype pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available bsl - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0036350 CG14111 - http://flybase.org/reports/FBgn0036350 protein_coding_gene - - - CG14111 - CG14111 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0085318 CG34289 - http://flybase.org/reports/FBgn0085318 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34289 "IPR001841:Zinc finger, RING-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR017907:Zinc finger, RING-type, conserved site" CG34289 27-Aug-18 DroID_v2018_08 "Drer\trim35-19, Drer\si:ch73-106l15.2, Drer\trim35-24, Drer\LOC100536643, Drer\trim35-34, Drer\trim35-10, Drer\trim35-31, Drer\trim35-29, Drer\trim35-14, Drer\si:ch211-175l6.2, Drer\trim35-25, Drer\trim35-35, Drer\trim35-9, Drer\si:ch211-12p12.2, Drer\trim35-28, Drer\trim35-3, Drer\rnf4, Drer\trim35-7, Drer\trim35-13, Drer\trim35-30, Drer\trim35-1, Drer\ftr70, Drer\si:ch73-166o21.1, Drer\si:ch1073-324l1.1, Drer\trim35-12, Drer\trim35-20, Drer\trim35-33, Drer\si:ch73-106l15.3, Drer\trim35-23" - "Cele\C28G1.6, Cele\T01G5.7, Cele\Y38C1AA.6" "Xtro\trim69.2, Xtro\rnf4" "Mmus\Trim35, Mmus\Trim7, Mmus\Trim10, Mmus\Rnf4, Mmus\Trim26" "Hsap\TRIM26, Hsap\RNF4, Hsap\TRIM10, Hsap\TRIM7, Hsap\TRIM35" FBgn0000749 fs(1)A336 female sterile (1) A336 http://flybase.org/reports/FBgn0000749 - gene - - - "fs(1)336, fs(1)A336" - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive" egg FBgn0051956 Pgant4 polypeptide GalNAc transferase 4 http://flybase.org/reports/FBgn0051956 protein_coding_gene polypeptide N-acetylgalactosaminyltransferase activity ; GO:0004653 | inferred from direct assay positive regulation of secretion ; GO:0051047 | inferred from mutant phenotype protein O-linked glycosylation ; GO:0006493 | inferred from mutant phenotype secretory granule organization ; GO:0033363 | inferred from mutant phenotype oligosaccharide biosynthetic process ; GO:0009312 | inferred from direct assay Golgi stack ; GO:0005795 | non-traceable author statement "CG31956, CG8845b, CG8845, pgant4" "IPR000772:Ricin B, lectin domain, IPR001173:Glycosyltransferase 2-like, IPR029044:Nucleotide-diphospho-sugar transferases" CG31956 27-Aug-18 DroID_v2018_08 "Drer\LOC101886587, Drer\galnt14, Drer\galnt6, Drer\LOC101882942, Drer\galnt16, Drer\galnt8b, Drer\galnt1, Drer\galnt7, Drer\LOC568645, Drer\galnt2, Drer\poc1bl, Drer\galnt18b, Drer\LOC103910015, Drer\LOC100535692, Drer\galnt12, Drer\galnt8a.1, Drer\galnt10, Drer\wbscr17, Drer\galnt3, Drer\galnt13, Drer\galnt11, Drer\LOC100334784, Drer\si:ch211-15e22.3, Drer\galnt9" - "Cele\gly-10, Cele\gly-7, Cele\gly-9, Cele\gly-11, Cele\gly-3" "Xtro\galnt1, Xtro\galnt13, Xtro\galnt7, Xtro\wbscr17, Xtro\galnt16, Xtro\galnt4, Xtro\galnt2, Xtro\galnt10, Xtro\galnt9, Xtro\galnt14, Xtro\galnt12, Xtro\galnt15, Xtro\galnt6.1" "Mmus\Galntl5, Mmus\Galnt16, Mmus\Galnt6, Mmus\Galnt18, Mmus\Galnt10, Mmus\Galnt13, Mmus\Galnt9, Mmus\Galnt2, Mmus\Galnt1, Mmus\Galntl6, Mmus\Galnt4, Mmus\Galnt15, Mmus\Galnt14, Mmus\Galnt11, Mmus\Galnt3, Mmus\Galnt7, Mmus\Wbscr17, Mmus\Galnt12, Mmus\Galnt5" "Hsap\GALNT6, Hsap\GALNT4, Hsap\GALNTL6, Hsap\GALNT14, Hsap\WBSCR17, Hsap\GALNT12, Hsap\GALNT9, Hsap\GALNT2, Hsap\GALNT7, Hsap\GALNT16, Hsap\GALNT10, Hsap\POC1B-GALNT4, Hsap\GALNTL5, Hsap\GALNT5, Hsap\GALNT18, Hsap\GALNT11, Hsap\GALNT1, Hsap\GALNT3, Hsap\GALNT13, Hsap\GALNT8, Hsap\GALNT15" "lethal,viable" "embryonic/larval proventriculus outer layer,secretory granuleunspecified,secretory granuletim-02)" FBgn0030905 CG15059 - http://flybase.org/reports/FBgn0030905 protein_coding_gene - - - CG15059 - CG15059 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0262410 mir-6-2 mir-6-2 stem loop http://flybase.org/reports/FBgn0262410 miRNA_gene - negative regulation of cell death ; GO:0060548 | inferred from mutant phenotype - "mir-6-2, mir-6, 6-2, Dme-miR-6, miR-6-2, CR42954, miR-6, miR6-2, CR33040, dme-mir-6-2" - CR42954 27-Aug-18 DroID_v2018_08 - - - - - - " embryonic stage , larval stage | first instar " "visible,lethal" wing FBgn0011632 l(2)T57h10 lethal (2) T57h10 http://flybase.org/reports/FBgn0011632 FBgn0005177 gene - - - l(2)T57h10 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0000309 chl chaetelle http://flybase.org/reports/FBgn0000309 - gene - - - chl - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive,female sterile" "macrochaeta,wing vein,genitalia,adult abdomen" FBgn0039459 IntS12 Integrator 12 http://flybase.org/reports/FBgn0039459 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001965 snRNA 3'-end processing ; GO:0034472 | inferred from direct assay snRNA processing ; GO:0016180 | inferred from sequence or structural similarity with HGNC:25067 neurogenesis ; GO:0022008 | inferred from mutant phenotype integrator complex ; GO:0032039 | inferred from sequence or structural similarity with HGNC:25067 "CG5491, IntS12, Int12" "IPR001965:Zinc finger, PHD-type, IPR011011:Zinc finger, FYVE/PHD-type, IPR019786:Zinc finger, PHD-type, conserved site, IPR019787:Zinc finger, PHD-finger, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG5491 27-Aug-18 DroID_v2018_08 "Drer\phf1, Drer\phf19, Drer\ints12, Drer\mtf2" - "Cele\phf-30, Cele\F53H1.4" "Xtro\phf19, Xtro\ints12, Xtro\phf1, Xtro\mtf2" "Mmus\Ints12, Mmus\Phf1, Mmus\Mtf2, Mmus\Phf19" "Hsap\INTS12, Hsap\PHF19, Hsap\MTF2, Hsap\PHF1" "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0000062 alb alberich http://flybase.org/reports/FBgn0000062 - gene molecular_function ; GO:0003674 | no biological data available blastoderm segmentation ; GO:0007350 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available alb - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,maternal effect" "embryonic abdominal segment,embryonic abdominal segment 1,embryonic abdominal segment 2,embryonic abdominal segment 3,embryonic abdominal segment 4,embryonic abdominal segment 5,embryonic abdominal segment 6,embryonic abdominal segment 7,embryonic abdominal segment 8,embryonic abdominal segment 9,embryonic abdominal segment 10,embryonic abdominal segment 11" FBgn0266502 s-256 - http://flybase.org/reports/FBgn0266502 gene - - - s-256 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259544 B2009 - http://flybase.org/reports/FBgn0259544 gene - - - B2009 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266906 asRNA:CR45366 - http://flybase.org/reports/FBgn0266906 non_protein_coding_gene - - - CR45366 - CR45366 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038384 CG5470 - http://flybase.org/reports/FBgn0038384 protein_coding_gene - - - CG5470 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267973 Ncoa6::sd - http://flybase.org/reports/FBgn0267973 engineered_fusion_gene - - - Ncoa6::sd - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0084094 E-3c1 Enhancer on chromosome 3-complementation group c1 http://flybase.org/reports/FBgn0084094 gene - - - "E-3c, E-3c1" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0283531 Duox Dual oxidase http://flybase.org/reports/FBgn0283531 protein_coding_gene NAD(P)H oxidase activity ; GO:0016174 | inferred from electronic annotation with InterPro:IPR029595 calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR010255 peroxidase activity ; GO:0004601 | inferred from direct assay "hydrogen peroxide biosynthetic process ; GO:0050665 | inferred from electronic annotation with InterPro:IPR029595 response to oxidative stress ; GO:0006979 | inferred from electronic annotation with InterPro:IPR010255 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR010255, InterPro:IPR013112, InterPro:IPR013121, InterPro:IPR017927, InterPro:IPR017938 defense response to bacterium ; GO:0042742 | inferred from mutant phenotype reactive oxygen species metabolic process ; GO:0072593 | inferred from mutant phenotype adult chitin-containing cuticle pigmentation ; GO:0048085 | inferred from mutant phenotype mucosal immune response ; GO:0002385 | inferred from mutant phenotype response to cAMP ; GO:0051591 | inferred from sequence or structural similarity with UniProtKB:Q9NRD8 adult chitin-based cuticle development ; GO:0008365 | inferred from mutant phenotype negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from mutant phenotype cytokine-mediated signaling pathway ; GO:0019221 | inferred from sequence or structural similarity with UniProtKB:Q9NRD9 imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype cuticle development ; GO:0042335 | inferred from sequence or structural similarity with UniProtKB:Q9NRD9" endomembrane system ; GO:0012505 | inferred from direct assay "Duox, DUOX, duox, Cy, l(2)23Bb, dDuox, CG3131, dduox" "IPR029595:Dual oxidase 1/Duox, IPR018247:EF-Hand 1, calcium-binding site, IPR002048:EF-hand domain, IPR010255:Haem peroxidase, IPR011992:EF-hand domain pair, IPR013112:FAD-binding 8, IPR013121:Ferric reductase, NAD binding domain, IPR013130:Ferric reductase transmembrane component-like domain, IPR017927:Ferredoxin reductase-type FAD-binding domain, IPR017938:Riboflavin synthase-like beta-barrel, IPR019791:Haem peroxidase, animal" CG3131 27-Aug-18 DroID_v2018_08 "Drer\duox, Drer\nox5, Drer\nox1, Drer\cybb" "Scer\FRE4, Scer\FRE5, Scer\FRE6, Scer\FRE2, Scer\FRE8, Scer\AIM14, Scer\FRE3, Scer\FRE7, Scer\FRE1" "Cele\bli-3, Cele\duox-2" "Xtro\nox1, Xtro\cybb, Xtro\nox5, Xtro\duox1, Xtro\duox2" "Mmus\Cybb, Mmus\Duox2, Mmus\Nox3, Mmus\Nox1, Mmus\Nox4, Mmus\Duox1" "Hsap\CYBB, Hsap\NOX5, Hsap\DUOX2, Hsap\NOX4, Hsap\NOX3, Hsap\NOX1, Hsap\DUOX1" "lethal,wild-type" wing FBgn0266170 pre-mod(mdg4)-C - http://flybase.org/reports/FBgn0266170 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "pre-mod(mdg4)-C, CG44876" IPR018379:BEN domain CG44876 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0026577 CG8677 - http://flybase.org/reports/FBgn0026577 "FBgn0032936, FBgn0046270" protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001965 "heterochromatin organization involved in chromatin silencing ; GO:0070868 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from sequence or structural similarity with UniProtKB:Q96T23" RSF complex ; GO:0031213 | inferred from physical interaction with Iswi nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q96T23 polytene chromosome interband ; GO:0005705 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay "LD14959, BEST:LD14959, BEST:LD19244, CG8677, dRsf-1, rsf-1" "IPR001965:Zinc finger, PHD-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR019786:Zinc finger, PHD-type, conserved site, IPR011011:Zinc finger, FYVE/PHD-type, IPR019787:Zinc finger, PHD-finger, IPR018501:DDT domain" CG8677 27-Aug-18 DroID_v2018_08 "Drer\rsf1a, Drer\rsf1b.1" - - Xtro\rsf1 Mmus\Rsf1 "Hsap\RSF1, Hsap\CECR2" "long lived,partially lethal - majority die,lethal,viable,fertile,suppressor of variegation,dominant" DRSC21844 IE -0.269192362 2.43078016 1.203768388 1.516851112 -0.347434054 -0.989099814 FBgn0044451 EP682 EP682 http://flybase.org/reports/FBgn0044451 gene - - - EP682 - - 27-Aug-18 DroID_v2018_08 - - - - - - neuroanatomy defective "intersegmental nerve,anterior fascicle & synapse" FBgn0040076 primo-2 primo-2 http://flybase.org/reports/FBgn0040076 protein_coding_gene non-membrane spanning protein tyrosine phosphatase activity ; GO:0004726 | inferred from electronic annotation with InterPro:IPR002115 acid phosphatase activity ; GO:0003993 | inferred from electronic annotation with InterPro:IPR002115 protein tyrosine phosphatase activity ; GO:0004725 | inferred from direct assay protein tyrosine phosphatase activity ; GO:0004725 | non-traceable author statement protein dephosphorylation ; GO:0006470 | inferred from direct assay protein dephosphorylation ; GO:0006470 | non-traceable author statement cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:122 cytoplasm ; GO:0005737 | non-traceable author statement "LMW-PTP, CG9599, primo, CG31311, CG33747, primo-2, Primo-2, BEO2" "IPR002115:Protein-tyrosine phosphatase, low molecular weight, mammalian, IPR017867:Protein-tyrosine phosphatase, low molecular weight, IPR023485:Phosphotyrosine protein phosphatase I superfamily" CG33747 27-Aug-18 DroID_v2018_08 Drer\acp1 Scer\LTP1 Cele\Y94H6A.7 Xtro\acp1 Mmus\Acp1 Hsap\ACP1 " embryonic stage , adult stage " " neuron &&of ventral nerve cord

, neuron &&of ventral nerve cord

, embryonic head

, embryonic epidermis | vicinity of

, embryonic/larval digestive system | restricted

" "viable,fertile" FBgn0060479 l(3)S111105 lethal (3) S111105 http://flybase.org/reports/FBgn0060479 gene - - - "1111/05, l(3)S111105" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0047199 CG31517 - http://flybase.org/reports/FBgn0047199 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:LD34214, CG31517" - CG31517 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,some die during pupal stage,viable" FBgn0015582 dare defective in the avoidance of repellents http://flybase.org/reports/FBgn0015582 - protein_coding_gene NADPH-adrenodoxin reductase activity ; GO:0015039 | inferred from sequence or structural similarity with UniProtKB:P22570 NADPH-adrenodoxin reductase activity ; GO:0015039 | inferred from biological aspect of ancestor with PANTHER:PTN000234268 electron carrier activity ; GO:0009055 | inferred from sequence or structural similarity with UniProtKB:P22570 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR021163, InterPro:IPR023753 steroid biosynthetic process ; GO:0006694 | inferred from expression pattern inferred from direct assay molting cycle, chitin-based cuticle ; GO:0007591 | inferred from mutant phenotype olfactory behavior ; GO:0042048 | inferred from mutant phenotype cholesterol catabolic process ; GO:0006707 | inferred from sequence or structural similarity with UniProtKB:P22570 pupariation ; GO:0035073 | inferred from mutant phenotype metamorphosis ; GO:0007552 | inferred from mutant phenotype" mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:P22570 "W8, AR, CG12390, dare, Dare" "IPR021163:Ferredoxin-NADP+ reductase, adrenodoxin-type, IPR023753:FAD/NAD(P)-binding domain" CG12390 27-Aug-18 DroID_v2018_08 "Drer\fdxr, Drer\cmtr2" "Scer\ARH1, Scer\GLT1" Cele\Y62E10A.6 "Xtro\cmtr2, Xtro\fdxr" "Mmus\Cmtr2, Mmus\Fdxr" Hsap\FDXR " adult stage , larval stage | third instar , adult stage && oogenesis stage | stage >=S6 " " ring gland

, nurse cell

, ovary

, prothoracic gland

" "viable,smell perception defective,recessive,courtship behavior defective,male,behavior defective,lethal - all die before end of larval stage,some die during larval stage,wild-type,lethal,dominant,maternal effect" "antennal lobe,optic lobe,ellipsoid body,fan-shaped body,thoracico-abdominal ganglion,egg,germline clone,egg chamber,mouth hooks,embryonic/larval anterior spiracle" FBgn0038721 subdued subdued http://flybase.org/reports/FBgn0038721 protein_coding_gene protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR032394 intracellular calcium activated chloride channel activity ; GO:0005229 | inferred from direct assay voltage-gated chloride channel activity ; GO:0005247 | inferred from direct assay temperature-gated ion channel activity ; GO:0097603 | inferred from direct assay chloride transport ; GO:0006821 | inferred from direct assay defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype - "CG16718, subdued" "IPR007632:Anoctamin, IPR032394:Anoctamin, dimerisation domain" CG16718 27-Aug-18 DroID_v2018_08 "Drer\LOC562630, Drer\si:dkey-83h2.5, Drer\LOC103910000, Drer\ano1, Drer\ano6, Drer\ano9b, Drer\ano5b, Drer\LOC563500, Drer\ano5a, Drer\ano8a, Drer\ano3, Drer\LOC101886884, Drer\ano8b, Drer\ano2, Drer\ano11" Scer\IST2 "Cele\anoh-2, Cele\anoh-1" "Xtro\ano2, Xtro\ano3, Xtro\ano1, Xtro\ano9, Xtro\ano5" "Mmus\Ano2, Mmus\Ano7, Mmus\Ano1, Mmus\Ano8, Mmus\Ano4, Mmus\Ano3, Mmus\Ano5, Mmus\Ano9, Mmus\Ano6" "Hsap\ANO3, Hsap\ANO6, Hsap\ANO1, Hsap\ANO2, Hsap\ANO8, Hsap\ANO7, Hsap\ANO4, Hsap\ANO9, Hsap\ANO5" "immune response defective,viable,fertile" FBgn0051143 tRNA:Leu-CAA-2-3 transfer RNA:Leucine-CAA 2-3 http://flybase.org/reports/FBgn0051143 tRNA_gene UUG codon-amino acid adaptor activity ; GO:0033404 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033404 cytosol ; GO:0005829 | inferred by curator from GO:0033404 "AE002708.trna37-LeuCAA, tRNA:L:CAA:AE002708, CR31143, chr3R.trna43-LeuCAA, tRNA:LeuCAA, tRNA-Leu-CAA-2-3, tRNA:Leu-CAA-2-3, tRNA:CR31143, UUG" - CR31143 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030178 CG2974 - http://flybase.org/reports/FBgn0030178 protein_coding_gene NADHX epimerase activity ; GO:0052856 | inferred from biological aspect of ancestor with PANTHER:PTN000325829 NADPHX epimerase activity ; GO:0052857 | inferred from biological aspect of ancestor with PANTHER:PTN000325829 - mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000325829 CG2974 "IPR004443:YjeF N-terminal domain, IPR032976:YjeF N-terminal domain-containing protein, eukaryotes" CG2974 27-Aug-18 DroID_v2018_08 "Drer\edc3, Drer\yjefn3, Drer\apoa1bp" "Scer\EDC3, Scer\YNL200C" Cele\Y18D10A.3 "Xtro\edc3, Xtro\apoa1bp" "Mmus\Ttc24, Mmus\Edc3, Mmus\Apoa1bp" "Hsap\EDC3, Hsap\YJEFN3, Hsap\NAXE" "viable,fertile,visible" trichogen cell FBgn0040962 CG15868 - http://flybase.org/reports/FBgn0040962 protein_coding_gene - - - CG15868 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0058239 CG40239 - http://flybase.org/reports/FBgn0058239 protein_coding_gene - - - CG40239 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266224 lncRNA:CR44919 - http://flybase.org/reports/FBgn0266224 non_protein_coding_gene - - - CR44919 - CR44919 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263704 T:SS-hh Signal sequence of hh http://flybase.org/reports/FBgn0263704 engineered_tag - - - "T:SS-hh, T:hh" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0086358 Tab2 TAK1-associated binding protein 2 http://flybase.org/reports/FBgn0086358 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001876 "positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria ; GO:0006964 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype peptidoglycan recognition protein signaling pathway ; GO:0061057 | inferred from mutant phenotype positive regulation of protein import into nucleus, translocation ; GO:0033160 | inferred from mutant phenotype male courtship behavior, veined wing generated song production ; GO:0045433 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype positive regulation of defense response to virus by host ; GO:0002230 | inferred from mutant phenotype" - "CG7417, TAB2, TAB, dTAB2, 7417, ORF1, Tab2, galere, tab2, cg7417, dTab2, tab-2" "IPR003892:Ubiquitin system component Cue, IPR001876:Zinc finger, RanBP2-type, IPR032675:Leucine-rich repeat domain, L domain-like" CG7417 27-Aug-18 DroID_v2018_08 "Drer\btf3l4, Drer\tab2, Drer\btf3, Drer\tab3" "Scer\EGD1, Scer\WWM1, Scer\YML020W, Scer\BTT1" Cele\icd-1 Xtro\tab2 "Mmus\Btf3, Mmus\Tab2, Mmus\Tnfrsf1a, Mmus\Tab3, Mmus\Btf3l4" "Hsap\TAB2, Hsap\BTF3L4, Hsap\BTF3, Hsap\TAB3, Hsap\TNFRSF1A" FBgn0014145 deg degarni http://flybase.org/reports/FBgn0014145 - gene - - - deg - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible" "macrochaeta,microchaeta,sensillum campaniformium & wing,macrochaeta & leg,chemosensory sensory organ & proboscis" FBgn0051023 tRNA:Leu-TAG-1-2 transfer RNA:Leucine-TAG 1-2 http://flybase.org/reports/FBgn0051023 tRNA_gene CUA codon-amino acid adaptor activity ; GO:0033419 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033419 cytosol ; GO:0005829 | inferred by curator from GO:0033419 "AE002708.trna32-LeuTAG, tRNA:L:TAG:AE002708-a, CR31023, chr3R.trna38-LeuTAG, tRNA-Leu-TAG-1-2, tRNA:Leu-TAG-1-2, tRNA:CR31023" - CR31023 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0016760 Ybb Y-bobbed http://flybase.org/reports/FBgn0016760 - rRNA_gene - - - "rDNA, rRNA, NO, bb[Y], Y rDNA, bb, Ybb, Y,rDNA" - - 27-Aug-18 DroID_v2018_08 - - - - - - male fertile FBgn0051076 CG31076 - http://flybase.org/reports/FBgn0051076 protein_coding_gene - - - "CT19744, CG6309, CG31076" "IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like" CG31076 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-237i5.4, Drer\LOC100331330, Drer\c13h10orf11" Scer\LEA1 Cele\T19D7.6 Xtro\c10orf11 Mmus\1700112E06Rik Hsap\C10orf11 "viable,body color defective" mesothoracic tergum FBgn0263884 l(3)A42 - http://flybase.org/reports/FBgn0263884 gene - - - l(3)A42 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,cell cycle defective,somatic clone" "embryonic/larval brain,somatic clone,embryonic/larval neuroblast" FBgn0036486 Msh6 Msh6 http://flybase.org/reports/FBgn0036486 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000432, InterPro:IPR007695, InterPro:IPR007696, InterPro:IPR007860, InterPro:IPR007861, InterPro:IPR016151 mismatched DNA binding ; GO:0030983 | inferred from electronic annotation with InterPro:IPR000432, InterPro:IPR007695, InterPro:IPR007696, InterPro:IPR007860, InterPro:IPR007861, InterPro:IPR016151" DNA repair ; GO:0006281 | inferred from sequence or structural similarity with SGD:S000002504 meiotic mismatch repair ; GO:0000710 | inferred from mutant phenotype - "Msh6, CG7003" "IPR000432:DNA mismatch repair protein MutS, C-terminal, IPR007695:DNA mismatch repair protein MutS-like, N-terminal, IPR007696:DNA mismatch repair protein MutS, core, IPR007860:DNA mismatch repair protein MutS, connector domain, IPR007861:DNA mismatch repair protein MutS, clamp, IPR016151:DNA mismatch repair protein MutS, N-terminal, IPR015536:DNA mismatch repair protein MutS-homologue MSH6, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG7003 27-Aug-18 DroID_v2018_08 "Drer\msh3, Drer\msh6" "Scer\MSH1, Scer\MSH3, Scer\MSH6" Cele\msh-6 "Xtro\msh6, Xtro\msh3" "Mmus\Msh6, Mmus\Msh3" "Hsap\MSH3, Hsap\MSH6" "viable,fertile" FBgn0262391 mir-184 mir-184 stem loop http://flybase.org/reports/FBgn0262391 miRNA_gene - "anterior/posterior axis specification, embryo ; GO:0008595 | inferred from mutant phenotype oocyte dorsal/ventral axis specification ; GO:0007310 | inferred from mutant phenotype" - "miR-184, mir-184, dme-mir-184, 184, MIR-184, CR42925, CR33576, dme-miR-184, CR33577, mir-184*, miR-184S, mir-184S, miR-184*, dme-miR-184-3p" - CR42925 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0261733 EC4056 - http://flybase.org/reports/FBgn0261733 gene - - - EC4056 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0067753 l(1)G0135 lethal (1) G0135 http://flybase.org/reports/FBgn0067753 gene - - - l(1)G0135 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0265582 lncRNA:CR44409 - http://flybase.org/reports/FBgn0265582 non_protein_coding_gene - - - CR44409 - CR44409 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000526 dusky-body dusky body http://flybase.org/reports/FBgn0000526 - gene - - - "dusky-body, dyb" - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,male fertile,female sterile,eye color defective,body color defective" "adult thorax,pigment cell,eye,wing" FBgn0065240 l(2)SH2156 lethal (2) SH2156 http://flybase.org/reports/FBgn0065240 gene - - - "l(2)SH2156, l(2)SH2 2156" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0013524 l(2)23AB2 lethal (2) 23AB2 http://flybase.org/reports/FBgn0013524 - gene - - - "l(2)23Ae, l(2)23AB2" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage,lethal" FBgn0038203 Or88a Odorant receptor 88a http://flybase.org/reports/FBgn0038203 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | inferred from direct assay detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 "88a, DOR99, 88A.1, CG14360, Or88a, or88a, DmOr88a" "IPR004117:Olfactory receptor, insect" CG14360 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0069342 TAHRE\gag TAHRE element gag http://flybase.org/reports/FBgn0069342 transposable_element_gene - - - "GAG, TAHRE\gag, TAHRE gag" IPR006579:Pre-C2HC domain - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0003933 snRNA:U5:14B small nuclear RNA U5 at 14B http://flybase.org/reports/FBgn0003933 FBgn0003932 snRNA_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity" U5 snRNP ; GO:0005682 | inferred from sequence or structural similarity "U5, U5-14B, snRNA[[3]], K2, dU5, snRNA:U5, snRNA4, snRNA3, U5snRNA14B, CR32914, U5snRNA, snRNA:U5:14B, U5var:14B, U5:14B, U5 snRNA, U5 snRNA 14B, 14B U5" - CR32914 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262006 CG42824 - http://flybase.org/reports/FBgn0262006 protein_coding_gene - - - "CG42824, CG34053, HDC14119" - CG42824 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263970 lncRNA:CR43724 - http://flybase.org/reports/FBgn0263970 non_protein_coding_gene - - - "CR43724, lincRNA.263" - CR43724 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0250738 l(3)S026909 lethal (3) S026909 http://flybase.org/reports/FBgn0250738 gene - - - "l(3)S026909, l(3)s026909" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0262561 Xanthias\polyprotein - http://flybase.org/reports/FBgn0262561 transposable_element_gene - - - "Xanthias\polyprotein, polyprotein" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0020849 if::mew if::mew http://flybase.org/reports/FBgn0020849 - engineered_fusion_gene - - - if::mew - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0054039 CG34039 - http://flybase.org/reports/FBgn0054039 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BP1005, CG34039" IPR017920:COMM domain CG34039 27-Aug-18 DroID_v2018_08 Drer\commd4 - Cele\T28F2.2 Xtro\commd4 Mmus\Commd4 "Hsap\COMMD7, Hsap\COMMD4" FBgn0038107 CG17327 - http://flybase.org/reports/FBgn0038107 protein_coding_gene aminoacyl-tRNA hydrolase activity ; GO:0004045 | inferred from electronic annotation with InterPro:IPR002833 - - CG17327 "IPR023476:Peptidyl-tRNA hydrolase II domain, IPR002833:Peptidyl-tRNA hydrolase, PTH2" CG17327 27-Aug-18 DroID_v2018_08 "Drer\ptrh2, Drer\si:dkey-19e4.5" Scer\PTH2 Cele\C24G6.8 Xtro\ptrh2 Mmus\Ptrh2 Hsap\PTRH2 FBgn0267563 lncRNA:CR45903 - http://flybase.org/reports/FBgn0267563 non_protein_coding_gene - - - CR45903 - CR45903 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259481 Mob2 Mob2 http://flybase.org/reports/FBgn0259481 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9NBK5 protein kinase binding ; GO:0019901 | inferred from physical interaction with trc long-term memory ; GO:0007616 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype rhabdomere development ; GO:0042052 | inferred from mutant phenotype learning or memory ; GO:0007611 | inferred from mutant phenotype negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype cell morphogenesis ; GO:0000902 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay rhabdomere ; GO:0016028 | inferred from direct assay cell hair ; GO:0070451 | inferred from direct assay cell periphery ; GO:0071944 | inferred from direct assay "Mob1, CG11711, DMob2, dmob2, BEST:GH06341, CG11712, BcDNA:GH13236, Mob2, Dmob2, Dmob1, gh06341, MobI, trezor" IPR005301:MOB kinase activator family CG11711 27-Aug-18 DroID_v2018_08 "Drer\mob2b, Drer\LOC799520, Drer\mob1a, Drer\mob1ba, Drer\mob1bb, Drer\mob2a" "Scer\MOB2, Scer\MOB1" Cele\F09A5.4 "Xtro\mob1b, Xtro\mob1a, Xtro\mob2.1, Xtro\mob2.2" "Mmus\Mob2, Mmus\Mob1b, Mmus\Mob1a" "Hsap\MOB1A, Hsap\MOB1B, Hsap\MOB2" FBgn0002112 l(2)ax lethal (2) ax http://flybase.org/reports/FBgn0002112 - gene - - - l(2)ax - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0002780 mod modulo http://flybase.org/reports/FBgn0002780 FBgn0011255 protein_coding_gene mRNA binding ; GO:0003729 | inferred from sequence or structural similarity sequence-specific DNA binding ; GO:0043565 | inferred from direct assay DNA binding ; GO:0003677 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with nej cell proliferation ; GO:0008283 | inferred from mutant phenotype spermatid development ; GO:0007286 | inferred from mutant phenotype nucleolus ; GO:0005730 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay protein complex ; GO:0043234 | inferred from physical interaction with nej "0952/14, ms(3)100EF, CG2050, mod, Mod" IPR000504:RNA recognition motif domain CG2050 27-Aug-18 DroID_v2018_08 - - - - Mmus\Ncl Hsap\NCL " embryonic stage | stage 9 , embryonic stage | cellular blastoderm , embryonic stage | stage 10-12 , embryonic stage | stage 15 , embryonic stage | stage 8-10 , embryonic stage " " procephalic segment

, posterior embryonic/larval midgut

, visceral mesoderm

, mitotic domain 1,2,4,5,6,10,13,22,23

, cephalopharyngeal skeleton

, anterior embryonic/larval midgut

, head

, anal pad

, somatic mesoderm

, head mesoderm

, larval muscle system

, mesoderm

" "developmental rate defective,decreased cell size,viable,male sterile,Minute,male semi-sterile,recessive,lethal - all die before end of larval stage,some die during larval stage,wild-type,lethal,polyphasic,suppressor of variegation,dominant,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,cell autonomous,somatic clone,lethal - all die before end of P-stage,some die during pharate adult stage,increased cell death,increased cell size,mitotic cell cycle defective" "embryonic maxillary segment,embryonic mandibular segment,adult head,somatic clone,macrochaeta,somatic muscle,embryonic/larval posterior spiracle,embryonic labial segment,adult thorax,leg,adult abdomen,adult thorax & macrochaeta | somatic clone | cell autonomous,cell autonomous,embryonic/larval midgut" FBgn0011069 l(1)Q22 lethal (1) Q22 http://flybase.org/reports/FBgn0011069 FBgn0010210 gene - - - l(1)Q22 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0039469 TwdlC TweedleC http://flybase.org/reports/FBgn0039469 protein_coding_gene structural constituent of chitin-based cuticle ; GO:0005214 | inferred from sequence or structural similarity with TwdlF chitin-based cuticle development ; GO:0040003 | inferred from sequence or structural similarity with TwdlF proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity with TwdlF "TwdlC, CG14254" IPR004145:Domain of unknown function DUF243 CG14254 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,some die during pupal stage" FBgn0022976 shoc short circuit http://flybase.org/reports/FBgn0022976 - gene - - - shoc - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040213 fs(?)BP73 fs(?)BP73 http://flybase.org/reports/FBgn0040213 gene - - - fs(?)BP73 - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive" FBgn0000057 adp adipose http://flybase.org/reports/FBgn0000057 "FBgn0034305, FBgn0061182" protein_coding_gene molecular_function ; GO:0003674 | no biological data available lipid metabolic process ; GO:0006629 | inferred from mutant phenotype regulation of lipid storage ; GO:0010883 | inferred from mutant phenotype negative regulation of sequestering of triglyceride ; GO:0010891 | inferred from mutant phenotype carbohydrate metabolic process ; GO:0005975 | traceable author statement response to desiccation ; GO:0009269 | inferred from mutant phenotype lipid metabolic process ; GO:0006629 | traceable author statement cellular_component ; GO:0005575 | no biological data available "anon-WO0196371.3, anon-WO0196371.1, CG5124, anon-WO0196371.27, adp" "IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat, IPR019775:WD40 repeat, conserved site" CG5124 27-Aug-18 DroID_v2018_08 "Drer\wdtc1, Drer\dcaf8" Scer\COP1 Cele\adpr-1 "Xtro\dcaf8, Xtro\dcaf6, Xtro\wdtc1" "Mmus\Dcaf8, Mmus\Wdtc1, Mmus\Dcaf6" "Hsap\DCAF8, Hsap\DCAF6, Hsap\WDTC1" "lethal - all die before end of pupal stage,some die during pupal stage,viable,fertile,male fertile,female fertile,stress response defective,locomotor behavior defective,recessive,starvation stress response defective,dominant,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "embryonic/larval fat body,fat body,adult fat body,yolk,adult corpus allatum,dorsal appendage,oocyte,female,lipid particle" FBgn0037623 CG9801 - http://flybase.org/reports/FBgn0037623 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR001932 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG9801 IPR001932:PPM-type phosphatase domain CG9801 27-Aug-18 DroID_v2018_08 - - Cele\F33G12.6 - - - FBgn0261928 CG42795 - http://flybase.org/reports/FBgn0261928 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with Evi5 Rab GTPase binding ; GO:0017137 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 GTPase activator activity ; GO:0005096 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 regulation of vesicle fusion ; GO:0031338 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 regulation of GTPase activity ; GO:0043087 | inferred from sequence or structural similarity with Evi5 activation of GTPase activity ; GO:0090630 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 intracellular ; GO:0005622 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 endomembrane system ; GO:0012505 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 "CG42795, CG3996, CG12816, CG34108" "IPR032738:TBC1 domain family member 30, C-terminal, IPR000195:Rab-GTPase-TBC domain" CG42795 27-Aug-18 DroID_v2018_08 "Drer\tbc1d2, Drer\grtp1a, Drer\grtp1b, Drer\tbc1d8, Drer\tbc1d30, Drer\tbc1d9b, Drer\tbc1d2b, Drer\si:dkey-110k5.6, Drer\tbc1d9" "Scer\BUB2, Scer\MSB3, Scer\MDR1, Scer\MSB4" "Cele\tbc-9, Cele\tbc-19, Cele\tbc-18, Cele\tbc-2" "Xtro\grtp1, Xtro\tbc1d30, Xtro\tbc1d2b" "Mmus\Tbc1d9b, Mmus\Tbc1d2b, Mmus\Tbc1d8, Mmus\Grtp1, Mmus\Tbc1d2, Mmus\Tbc1d30, Mmus\Tbc1d9, Mmus\Tbc1d8b" "Hsap\GRTP1, Hsap\TBC1D9B, Hsap\TBC1D8B, Hsap\TBC1D8, Hsap\TBC1D2B, Hsap\TBC1D30, Hsap\TBC1D9, Hsap\TBC1D2" FBgn0053476 CG33476 - http://flybase.org/reports/FBgn0053476 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33476 IPR010512:Protein of unknown function DUF1091 CG33476 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065822 l(2)SH0366 lethal (2) SH0366 http://flybase.org/reports/FBgn0065822 gene - - - "l(2)SH0366, l(2)SH2 0366" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0003072 pg prong http://flybase.org/reports/FBgn0003072 - gene - - - pg - - 27-Aug-18 DroID_v2018_08 - - - - - - crossvein FBgn0004688 pby pebbly http://flybase.org/reports/FBgn0004688 - gene - - - pby - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "eye,ommatidium" FBgn0034475 Obp56h Odorant-binding protein 56h http://flybase.org/reports/FBgn0034475 protein_coding_gene odorant binding ; GO:0005549 | non-traceable author statement odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with UniProtKB:P34174 olfactory behavior ; GO:0042048 | inferred from sequence or structural similarity with UniProtKB:O02372 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with UniProtKB:P34174 response to pheromone ; GO:0019236 | inferred from sequence or structural similarity with UniProtKB:O02372 sensory perception of smell ; GO:0007608 | inferred from expression pattern extracellular region ; GO:0005576 | inferred from sequence model extracellular region ; GO:0005576 | inferred from sequence or structural similarity with UniProtKB:O02372 extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 "Obp56h, 56h, CG13874, OBP56h, DmelObp56h" IPR006170:Pheromone/general odorant binding protein CG13874 27-Aug-18 DroID_v2018_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0017629 Eig34C Eig34C http://flybase.org/reports/FBgn0017629 - gene - - - "Eig34, Eig34C" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032804 CG13081 - http://flybase.org/reports/FBgn0032804 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13081 - CG13081 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0017417 axe axed on X http://flybase.org/reports/FBgn0017417 - gene molecular_function ; GO:0003674 | no biological data available axonogenesis ; GO:0007409 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available axe - - 27-Aug-18 DroID_v2018_08 - - - - - - chordotonal organ & axon | lateral FBgn0069160 mcl(3)Z2086 mcl(3)Z2086 http://flybase.org/reports/FBgn0069160 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z2086 - - 27-Aug-18 DroID_v2018_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0002465 l(3)SG19 lethal (3) SG19 http://flybase.org/reports/FBgn0002465 - gene - - - l(3)SG19 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" eye-antennal disc FBgn0032908 CG9270 - http://flybase.org/reports/FBgn0032908 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR011527, InterPro:IPR017871 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from biological aspect of ancestor with PANTHER:PTN000657997" transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000657997 lateral inhibition ; GO:0046331 | inferred from mutant phenotype integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000658000 "Dme_CG9270, CG9270" "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR011527:ABC transporter type 1, transmembrane domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR017871:ABC transporter, conserved site" CG9270 27-Aug-18 DroID_v2018_08 "Drer\cftr, Drer\LOC100329706, Drer\abcc6a, Drer\abcc6b.2, Drer\abcc12, Drer\abcc1, Drer\abcc9, Drer\abcc10, Drer\abcc5, Drer\abcc4, Drer\abcc3, Drer\abcc13, Drer\abcc8, Drer\abcc2" "Scer\NFT1, Scer\STE6, Scer\YKR104W, Scer\VMR1, Scer\BPT1, Scer\YCF1, Scer\YBT1, Scer\YOR1" "Cele\mrp-5, Cele\mrp-4, Cele\cft-1, Cele\mrp-2, Cele\mrp-3, Cele\mrp-8, Cele\mrp-7, Cele\mrp-6, Cele\mrp-1" "Xtro\abcc1, Xtro\abcc6, Xtro\abcc10, Xtro\abcc4, Xtro\abcc3, Xtro\cftr" "Mmus\Abcc10, Mmus\Abcc5, Mmus\Abcc1, Mmus\Abcc4, Mmus\Abcc9, Mmus\Abcc8, Mmus\Abcc12, Mmus\Cftr, Mmus\Abcc3, Mmus\Abcc2, Mmus\Abcc6" "Hsap\ABCC4, Hsap\ABCC1, Hsap\ABCC6, Hsap\ABCC3, Hsap\ABCC8, Hsap\ABCC5, Hsap\ABCC12, Hsap\ABCC10, Hsap\ABCC11, Hsap\ABCC2, Hsap\CFTR, Hsap\ABCC9" "viable,visible" chaeta FBgn0065670 l(2)SH0686 lethal (2) SH0686 http://flybase.org/reports/FBgn0065670 gene - - - "l(2)SH0686, l(2)SH2 0686" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0011868 tRNA:Gly-GCC-1-9 transfer RNA:Glycine-GCC 1-9 http://flybase.org/reports/FBgn0011868 "FBgn0050228, FBgn0060218" tRNA_gene GGC codon-amino acid adaptor activity ; GO:0033462 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033462 cytosol ; GO:0005829 | inferred by curator from GO:0033462 "CR30228, AE002787.trna10-GlyGCC, tRNA:G:GCC:AE002787-a, tRNA:gly3:55E, tRNA[Gly-GCC], chr2R.trna68-GlyGCC, tRNA-Gly-GCC-1-9, tRNA:Gly-GCC-1-9, tRNA:G3:55E, GGC" - CR30228 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035197 CG9130 - http://flybase.org/reports/FBgn0035197 protein_coding_gene - - - "CG32332, BEST:GH19464, BEST:GH19274, anon-WO0140519.53, anon-WO0140519.145, CG9130" - CG9130 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051340 CG31340 - http://flybase.org/reports/FBgn0051340 protein_coding_gene - - - CG31340 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0069128 mei(3)M19 mei(3)M19 http://flybase.org/reports/FBgn0069128 gene - male meiosis chromosome segregation ; GO:0007060 | inferred from mutant phenotype - mei(3)M19 - - 27-Aug-18 DroID_v2018_08 - - - - - - "meiotic cell cycle defective,male,recessive" FBgn0003890 betaTub97EF beta-Tubulin at 97EF http://flybase.org/reports/FBgn0003890 FBgn0039567 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR002453, InterPro:IPR008280, InterPro:IPR017975 structural constituent of cytoskeleton ; GO:0005200 | inferred from electronic annotation with InterPro:IPR002453 GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR003008, InterPro:IPR008280 structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity" centrosome duplication ; GO:0051298 | inferred from mutant phenotype "microtubule ; GO:0005874 | inferred from electronic annotation with InterPro:IPR000217, InterPro:IPR002453, InterPro:IPR017975 microtubule ; GO:0005874 | inferred from sequence or structural similarity neuromuscular junction ; GO:0031594 | microtubule ; GO:0005874 |" "beta-Tub, beta-tub, CG4869, BETA 98B, Dmbeta4, betaTub98C, T, 4t, betaTub98BC, DTB1, beta97F, B4t, betaTub4, beta4t, beta-Tub97EF, betaTub97EF, Tub, beta4, Tub2C" "IPR000217:Tubulin, IPR002453:Beta tubulin, IPR003008:Tubulin/FtsZ, GTPase domain, IPR008280:Tubulin/FtsZ, C-terminal, IPR017975:Tubulin, conserved site, IPR018316:Tubulin/FtsZ, 2-layer sandwich domain, IPR013838:Beta tubulin, autoregulation binding site" CG4869 27-Aug-18 DroID_v2018_08 "Drer\tubb5, Drer\tubb2b, Drer\zgc:65894, Drer\zgc:153426, Drer\zgc:55461, Drer\tubb1, Drer\tubb6, Drer\zgc:153264, Drer\tubb4b, Drer\tubb2" Scer\TUB2 "Cele\tbb-1, Cele\ben-1, Cele\tbb-4, Cele\tbb-2, Cele\mec-7" "Xtro\tubb4a, Xtro\tubb, Xtro\tubb6, Xtro\tubb3, Xtro\tube1, Xtro\tubb2b, Xtro\tubb4b" "Mmus\Tubb1, Mmus\Tube1, Mmus\Tubb4b, Mmus\Tubb2b, Mmus\Tubb2a, Mmus\Tubb4a, Mmus\Tubb6, Mmus\Tubb5, Mmus\Tubb3" "Hsap\TUBB4A, Hsap\TUBB2A, Hsap\TUBE1, Hsap\TUBB1, Hsap\TUBB2B, Hsap\TUBB6, Hsap\TUBB4B, Hsap\TUBB, Hsap\TUBB8, Hsap\TUBB3" " larval stage | second instar , embryonic stage | 0-21 hr , larval stage | third instar , pupal stage , prepupal stage , larval stage | first instar " "viable,fertile" DRSC15666 E 0.995962574 -0.674885018 3.76162945 -0.319934608 0.311230994 -0.491730244 FBgn0041237 Gr58c Gustatory receptor 58c http://flybase.org/reports/FBgn0041237 protein_coding_gene taste receptor activity ; GO:0008527 | non-traceable author statement sensory perception of taste ; GO:0050909 | inferred from electronic annotation with InterPro:IPR013604 sensory perception of taste ; GO:0050909 | non-traceable author statement integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 integral component of membrane ; GO:0016021 | non-traceable author statement "Gr58A3, CG13491, 58A3, 58A.3, GR58A.3, Gr58c, GR58c" IPR013604:7TM chemoreceptor CG13491 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC04136 I 1.637733002 0.410606826 0.530800863 0.5626311 -0.488423637 -0.91337785 FBgn0263384 lncRNA:CR43436 - http://flybase.org/reports/FBgn0263384 non_protein_coding_gene - - - CR43436 - CR43436 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0086712 Egm Enigma http://flybase.org/reports/FBgn0086712 protein_coding_gene "oxidoreductase activity, acting on the CH-CH group of donors ; GO:0016627 | inferred from electronic annotation with InterPro:IPR009075, InterPro:IPR009100, InterPro:IPR013786 flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR013786" compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with N response to endoplasmic reticulum stress ; GO:0034976 | inferred from mutant phenotype fatty acid beta-oxidation ; GO:0006635 | inferred from mutant phenotype negative regulation of cellular response to oxidative stress ; GO:1900408 | inferred from mutant phenotype lipid homeostasis ; GO:0055088 | inferred from mutant phenotype multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay "Egm, egm, l(2)k14708, CG9006, Acyl CoA DH" "IPR013786:Acyl-CoA dehydrogenase/oxidase, N-terminal, IPR009100:Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain, IPR009075:Acyl-CoA dehydrogenase/oxidase C-terminal" CG9006 27-Aug-18 DroID_v2018_08 "Drer\acad8, Drer\acads, Drer\acad9, Drer\acadm, Drer\acadvl" - "Cele\acdh-8, Cele\acdh-10, Cele\acdh-11, Cele\acdh-1, Cele\acdh-7, Cele\acdh-13, Cele\acdh-4, Cele\acdh-9" "Xtro\acadsb, Xtro\acad8, Xtro\acads, Xtro\ivd, Xtro\acad9, Xtro\MGC107841, Xtro\acadm" "Mmus\Acads, Mmus\Acad9, Mmus\Acadvl, Mmus\Acadsb, Mmus\Acadm, Mmus\Ivd, Mmus\Acad8" "Hsap\ACADVL, Hsap\ACADS, Hsap\ACADM, Hsap\IVD, Hsap\ACAD8, Hsap\ACADSB, Hsap\ACAD9" DRSC22860 E -0.262340114 1.107950714 2.136550482 1.636922164 0.718444034 0.707057362 FBgn0020931 Est-E Est-E http://flybase.org/reports/FBgn0020931 - gene - - - Est-E - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030017 CG2278 - http://flybase.org/reports/FBgn0030017 protein_coding_gene - - - CG2278 - CG2278 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0036714 CG7692 - http://flybase.org/reports/FBgn0036714 protein_coding_gene - - - CG7692 - CG7692 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" FBgn0069130 mei(2)yh217 mei(2)yh217 http://flybase.org/reports/FBgn0069130 gene - male meiosis chromosome segregation ; GO:0007060 | inferred from mutant phenotype - mei(2)yh217 - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,meiotic cell cycle defective,male,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" FBgn0267705 asRNA:CR46038 - http://flybase.org/reports/FBgn0267705 non_protein_coding_gene - - - CR46038 - CR46038 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259269 EP-493 - http://flybase.org/reports/FBgn0259269 gene - - - EP-493 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible wing FBgn0051473 CG31473 - http://flybase.org/reports/FBgn0051473 protein_coding_gene "FMN binding ; GO:0010181 | inferred from electronic annotation with InterPro:IPR011576, InterPro:IPR012349 pyridoxamine-phosphate oxidase activity ; GO:0004733 | inferred from biological aspect of ancestor with PANTHER:PTN000852047" "pyridoxine biosynthetic process ; GO:0008615 | inferred from electronic annotation with InterPro:IPR000659 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000659, InterPro:IPR011576, InterPro:IPR012349 pyridoxal phosphate biosynthetic process ; GO:0042823 | inferred from biological aspect of ancestor with PANTHER:PTN000852047" - "CG2649, CG31473" "IPR000659:Pyridoxamine 5'-phosphate oxidase, IPR011576:Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain, IPR012349:FMN-binding split barrel" CG31473 27-Aug-18 DroID_v2018_08 Drer\pnpo Scer\PDX3 Cele\F57B9.1 Xtro\pnpo Mmus\Pnpo Hsap\PNPO viable FBgn0051269 CG31269 - http://flybase.org/reports/FBgn0051269 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - "SP126, CG5233, CG31269" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG31269 27-Aug-18 DroID_v2018_08 "Drer\LOC560023, Drer\si:ch211-165b19.9, Drer\zgc:171509, Drer\zmp:0000001088, Drer\try" - "Cele\try-1, Cele\svh-1, Cele\nhl-3" - "Mmus\Klk1b8, Mmus\Prss55, Mmus\Klk1b16, Mmus\Klk1b4, Mmus\Klk13, Mmus\Klk1b11, Mmus\Klk10, Mmus\Klk15, Mmus\Proz, Mmus\Klk1b3, Mmus\Egfbp2, Mmus\Klk14, Mmus\Klk7" "Hsap\KLK9, Hsap\KLK14, Hsap\PROZ, Hsap\KLK7, Hsap\KLK11" viable FBgn0060596 l(3)S092012b lethal (3) S092012b http://flybase.org/reports/FBgn0060596 gene - - - "0920/12, l(3)S092012b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0000209 Bpt Blackpatch http://flybase.org/reports/FBgn0000209 - gene - - - Bpt - - 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,recessive,female sterile,partially lethal - majority die,visible,dominant,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of P-stage,some die during pharate adult stage,lethal" eye FBgn0051161 CG31161 - http://flybase.org/reports/FBgn0051161 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG6943, CG31161" - CG31161 27-Aug-18 DroID_v2018_08 Drer\tsga10 - - - - - "viable,visible" trichogen cell DRSC25099 K -0.408154239 -0.501008354 0.604084125 -0.375322223 -1.508690417 -0.082845739 FBgn0033659 Damm Death associated molecule related to Mch2 caspase http://flybase.org/reports/FBgn0033659 protein_coding_gene cysteine-type endopeptidase activity ; GO:0004197 | traceable author statement cysteine-type endopeptidase activity ; GO:0004197 | inferred from sequence or structural similarity with Dredd inferred from sequence or structural similarity with Dronc inferred from sequence or structural similarity with Strica inferred from sequence or structural similarity with HGNC:1503 inferred from direct assay cysteine-type endopeptidase activity involved in apoptotic process ; GO:0097153 | inferred from biological aspect of ancestor with PANTHER:PTN000047947 larval midgut histolysis ; GO:0035069 | inferred from electronic annotation with InterPro:IPR033176 programmed cell death ; GO:0012501 | inferred from genetic interaction with hid proteolysis ; GO:0006508 | inferred from direct assay apoptotic process ; GO:0006915 | inferred from direct assay programmed cell death ; GO:0012501 | traceable author statement cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with Strica cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000047947 "Damm/Daydream, Daydream, CG18188, damm, DAMM, Damm" "IPR001309:Peptidase C14, p20 domain, IPR002138:Peptidase C14, caspase non-catalytic subunit p10, IPR015917:Peptidase C14A, caspase catalytic domain, IPR033176:Caspase DECAY, IPR029030:Caspase-like domain" CG18188 27-Aug-18 DroID_v2018_08 "Drer\caspxa, Drer\casp6l1, Drer\si:ch211-195h23.3, Drer\caspb, Drer\LOC798445, Drer\LOC101886133, Drer\pea15, Drer\caspa, Drer\casp7, Drer\cflara, Drer\gbp3, Drer\casp8l1, Drer\LOC100331324, Drer\zgc:171731, Drer\casp6l2, Drer\caspbl, Drer\casp8l2, Drer\casp9, Drer\casp3b, Drer\casp2, Drer\casp8, Drer\casp3a, Drer\casp6" - "Cele\csp-2, Cele\ced-3, Cele\csp-1" "Xtro\pea15, Xtro\casp9, Xtro\casp2, Xtro\casp7, Xtro\casp6, Xtro\casp3, Xtro\LOC733553, Xtro\casp10, Xtro\casp1" "Mmus\Casp8, Mmus\Pea15a, Mmus\Casp9, Mmus\Casp7, Mmus\Casp14, Mmus\Casp3, Mmus\Casp6, Mmus\Casp2, Mmus\Casp1, Mmus\Casp4, Mmus\Cflar, Mmus\Pycard, Mmus\Casp12" "Hsap\CASP6, Hsap\CASP7, Hsap\CARD18, Hsap\CFLAR, Hsap\CASP14, Hsap\CASP1, Hsap\PYCARD, Hsap\PEA15, Hsap\CASP2, Hsap\CASP8, Hsap\CARD16, Hsap\CASP9, Hsap\CASP10, Hsap\CASP5, Hsap\CARD17, Hsap\CASP3, Hsap\CASP4, Hsap\CARD8" "viable,fertile,visible,increased cell death" "eye,ommatidium" FBgn0259472 EP-140 - http://flybase.org/reports/FBgn0259472 gene - - - EP-140 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing hair,wing,wing vein" FBgn0061142 l(3)S000616c lethal (3) S000616c http://flybase.org/reports/FBgn0061142 gene - - - "0006/16, l(3)S000616c" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0260497 l(3)12563 - http://flybase.org/reports/FBgn0260497 gene - - - l(3)12563 - - 27-Aug-18 DroID_v2018_08 - - - - - - neuroanatomy defective dendritic arborizing neuron FBgn0265158 CG44227 - http://flybase.org/reports/FBgn0265158 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44227 - CG44227 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0022971 snRNP54K snRNP54K http://flybase.org/reports/FBgn0022971 - gene - - - "54K, snRNP54K" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0024572 l(3)L7321 lethal (3) L7321 http://flybase.org/reports/FBgn0024572 - gene - - - l(3)L7321 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0003027 ovl ovaless http://flybase.org/reports/FBgn0003027 - gene - - - ovl - - 27-Aug-18 DroID_v2018_08 - - - - - - "male fertile,female sterile" "eye,abdomen,female,ovary" FBgn0267883 CR46171 - http://flybase.org/reports/FBgn0267883 pseudogene_attribute - - - "CR46171, CG12717-related" - CR46171 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262527 nsl1 non-specific lethal 1 http://flybase.org/reports/FBgn0262527 protein_coding_gene core promoter binding ; GO:0001047 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Rcd5 histone acetyltransferase binding ; GO:0035035 | inferred from physical interaction with mof "mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs germarium-derived female germ-line cyst formation ; GO:0030727 | inferred from genetic interaction with nos larval somatic muscle development ; GO:0007526 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype germ-line stem cell population maintenance ; GO:0030718 | inferred from genetic interaction with nos regulation of endocytosis ; GO:0030100 | inferred from mutant phenotype neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from genetic interaction with nos" nucleus ; GO:0005634 | inferred from direct assay polytene chromosome interband ; GO:0005705 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay NSL complex ; GO:0044545 | inferred from direct assay "CG4699, NSL1, nsl1, l(3)S009413, l(3)06536, E(nos), Nsl1, wah" "IPR029332:PEHE domain, IPR026180:KAT8 regulatory NSL complex subunit 1" CG4699 27-Aug-18 DroID_v2018_08 "Drer\kansl1b, Drer\kansl1l, Drer\kansl1a, Drer\LOC100333241" - Cele\mltn-11 Xtro\kansl1l "Mmus\Kansl1l, Mmus\Kansl1" "Hsap\KANSL1L, Hsap\KANSL1" DRSC15625 EK -0.878285485 1.420826987 -0.614001692 -7.10763892 -1.862795053 -0.120618708 FBgn0264959 Src42A Src oncogene at 42A http://flybase.org/reports/FBgn0264959 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 protein tyrosine kinase activity ; GO:0004713 | inferred from direct assay non-membrane spanning protein tyrosine kinase activity ; GO:0004715 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 protein tyrosine kinase activity ; GO:0004713 | non-traceable author statement receptor binding ; GO:0005102 | inferred from biological aspect of ancestor with PANTHER:PTN000700357" "adherens junction organization ; GO:0034332 | inferred from mutant phenotype defense response to bacterium ; GO:0042742 | inferred from mutant phenotype negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from genetic interaction with Ras85D tricarboxylic acid cycle ; GO:0006099 | inferred from direct assay imaginal disc fusion, thorax closure ; GO:0046529 | inferred from mutant phenotype negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from genetic interaction with Fak apoptotic cell clearance ; GO:0043277 | inferred from mutant phenotype actin filament bundle assembly ; GO:0051017 | inferred from mutant phenotype dorsal closure, spreading of leading edge cells ; GO:0007395 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype peptidyl-tyrosine autophosphorylation ; GO:0038083 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 axon guidance ; GO:0007411 | inferred from mutant phenotype JNK cascade ; GO:0007254 | traceable author statement dorsal closure ; GO:0007391 | inferred from mutant phenotype inferred from genetic interaction with FER cell migration ; GO:0016477 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement peptidyl-tyrosine phosphorylation ; GO:0018108 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from direct assay inferred from mutant phenotype epithelial cell-cell adhesion ; GO:0090136 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype innate immune response ; GO:0045087 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 intestinal stem cell homeostasis ; GO:0036335 | inferred from mutant phenotype regulation of synaptic plasticity ; GO:0048167 | inferred from genetic interaction with GluRIIA dorsal closure ; GO:0007391 | traceable author statement salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype inferred from genetic interaction with bsk inferred from genetic interaction with hep inferred from genetic interaction with Src64B regulation of cell proliferation ; GO:0042127 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 transmembrane receptor protein tyrosine kinase signaling pathway ; GO:0007169 | inferred from genetic interaction with Raf" adherens junction ; GO:0005912 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay extrinsic component of cytoplasmic side of plasma membrane ; GO:0031234 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 "Src42, Src42A, Src, CG44128, src42A, DSrc42A, src42, Dsrc42A, SRC 42A, CG7873, SK2-4, src, Dsrc41, dtk5, DmHD-29, Src41, Su(Raf)1, Su1, Dm SRC41, dtk-5, Su(phl)1, Su(D-raf)1, SRC42A, l(2)k10108, Tk5, HD-29, Dtk5, dSrc, Src42a, src42a, CG14471" "IPR011009:Protein kinase-like domain, IPR000719:Protein kinase domain, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain, IPR008266:Tyrosine-protein kinase, active site, IPR020635:Tyrosine-protein kinase, catalytic domain, IPR017441:Protein kinase, ATP binding site, IPR001452:SH3 domain, IPR000980:SH2 domain" CG44128 27-Aug-18 DroID_v2018_08 "Drer\sla1, Drer\btk, Drer\itk, Drer\jak3, Drer\zgc:194282, Drer\yrk, Drer\matk, Drer\yes1, Drer\ptk6b, Drer\sla, Drer\lyn, Drer\hck, Drer\src, Drer\jak1, Drer\csk, Drer\jak2b, Drer\abl1, Drer\si:ch73-340m8.2, Drer\fyna, Drer\ptk6a, Drer\lck, Drer\tec, Drer\fynb, Drer\abl2, Drer\frk, Drer\tyk2, Drer\jak2a, Drer\txk" - "Cele\src-2, Cele\F39B2.5, Cele\src-1, Cele\Y38H6C.20, Cele\abl-1, Cele\Y47G6A.5" "Xtro\csk, Xtro\lyn, Xtro\jak1, Xtro\frk, Xtro\abl2, Xtro\lck, Xtro\tyk2, Xtro\jak3, Xtro\abl1, Xtro\jak2, Xtro\tec, Xtro\src, Xtro\fgr, Xtro\yes1, Xtro\btk, Xtro\fyn" "Mmus\Fyn, Mmus\Srms, Mmus\Src, Mmus\Csk, Mmus\Hck, Mmus\Blk, Mmus\Jak2, Mmus\Btk, Mmus\Abl1, Mmus\Bmx, Mmus\Txk, Mmus\Yes1, Mmus\Jak3, Mmus\Abl2, Mmus\Frk, Mmus\Lck, Mmus\Sla, Mmus\Tyk2, Mmus\Ptk6, Mmus\Itk, Mmus\Sla2, Mmus\Tec, Mmus\Lyn, Mmus\Fgr, Mmus\Jak1, Mmus\Matk" "Hsap\SLA, Hsap\ABL1, Hsap\FRK, Hsap\JAK3, Hsap\ABL2, Hsap\FGR, Hsap\ITK, Hsap\CSK, Hsap\YES1, Hsap\TXK, Hsap\FYN, Hsap\BLK, Hsap\BMX, Hsap\MATK, Hsap\TYK2, Hsap\JAK1, Hsap\SRMS, Hsap\SRC, Hsap\LYN, Hsap\JAK2, Hsap\BTK, Hsap\SLA2, Hsap\PTK6, Hsap\LCK, Hsap\HCK, Hsap\TEC" " embryonic stage | stage 13-16 , larval stage | third instar , embryonic stage&&pupal stage , embryonic stage | early " " visceral mesoderm

, ventral thoracic disc

, supraesophageal ganglion

, anal pad

, embryonic/larval hindgut

, eye-antennal disc

, dorsal mesothoracic disc

, ventral nerve cord

, central nervous system

,

ubiquitous " DRSC04915 IEK -0.580107243 -3.939586829 -0.874133636 -6.546117287 -3.99074456 -2.832864398 FBgn0037916 CG5342 - http://flybase.org/reports/FBgn0037916 protein_coding_gene mannose-ethanolamine phosphotransferase activity ; GO:0051377 | inferred from biological aspect of ancestor with PANTHER:PTN000262246 GPI anchor biosynthetic process ; GO:0006506 | inferred from biological aspect of ancestor with PANTHER:PTN000262246 endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN000262246 CG5342 "IPR007070:GPI ethanolamine phosphate transferase 1, IPR017852:GPI ethanolamine phosphate transferase 1, C-terminal" CG5342 27-Aug-18 DroID_v2018_08 Drer\pign Scer\MCD4 Cele\Y54E10BR.1 - Mmus\Pign Hsap\PIGN "viable,fertile" FBgn0010131 l(1)tsW2 lethal (1) tsW2 http://flybase.org/reports/FBgn0010131 - gene - - - l(1)tsW2 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,heat sensitive" FBgn0022260 l(2)k00803 lethal (2) k00803 http://flybase.org/reports/FBgn0022260 - gene - - - l(2)k00803 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0052758 CG32758 - http://flybase.org/reports/FBgn0052758 protein_coding_gene phosphatidylinositol binding ; GO:0035091 | inferred from biological aspect of ancestor with PANTHER:PTN000965695 phosphatidylinositol-3-phosphate binding ; GO:0032266 | inferred from sequence or structural similarity with HGNC:20073 "signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR000159 intracellular protein transport ; GO:0006886 | inferred from sequence or structural similarity with HGNC:20073 retrograde transport, endosome to plasma membrane ; GO:1990126 | inferred from biological aspect of ancestor with PANTHER:PTN000965695 intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000965695" early endosome ; GO:0005769 | inferred from sequence or structural similarity with HGNC:20073 early endosome ; GO:0005769 | inferred from biological aspect of ancestor with PANTHER:PTN000965695 "CG3138, CG3130, CG11465, CG32758, DmSNX27" "IPR000159:Ras-associating (RA) domain, IPR001478:PDZ domain, IPR001683:Phox homologous domain, IPR029071:Ubiquitin-related domain" CG32758 27-Aug-18 DroID_v2018_08 "Drer\snx27a, Drer\snx13, Drer\snx14, Drer\snx27b" Scer\MDM1 "Cele\snx-14, Cele\snx-27, Cele\snx-13" Xtro\snx27 "Mmus\Snx25, Mmus\Snx13, Mmus\Snx14, Mmus\Snx27" "Hsap\SNX14, Hsap\SNX25, Hsap\SNX27, Hsap\SNX13" "viable,visible" trichogen cell FBgn0003907 tyl tinylike http://flybase.org/reports/FBgn0003907 - gene - - - "ty-l, l(1)10Cb, tyl" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive,visible,viable,poor,lethal" macrochaeta FBgn0067351 l(3)95Ea lethal (3) 95Ea http://flybase.org/reports/FBgn0067351 gene - - - l(3)95Ea - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" "eye,somatic clone,mesothoracic tergum & macrochaeta | somatic clone,wing vein,wing margin" FBgn0028886 CG15279 - http://flybase.org/reports/FBgn0028886 protein_coding_gene neurotransmitter:sodium symporter activity ; GO:0005328 | inferred from electronic annotation with InterPro:IPR000175 cation:amino acid symporter activity ; GO:0005416 | inferred from sequence model transporter activity ; GO:0005215 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 neurotransmitter transporter activity ; GO:0005326 | inferred from sequence or structural similarity with DAT cation:amino acid symporter activity ; GO:0005416 | inferred from sequence or structural similarity amino acid transmembrane import ; GO:0044745 | inferred from sequence model neurotransmitter transport ; GO:0006836 | inferred from sequence or structural similarity with DAT transport ; GO:0006810 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 integral component of membrane ; GO:0016021 | inferred from sequence model "DS03431.1, BG:DS03431.1, anon-WO0149848.9, CG15279, DmNAT6" IPR000175:Sodium:neurotransmitter symporter CG15279 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-132b12.1, Drer\slc6a15, Drer\slc6a13, Drer\slc6a11a, Drer\slc6a5, Drer\slc6a16b, Drer\slc6a1l, Drer\slc6a19a.1, Drer\si:ch211-132b12.2, Drer\slc6a16a, Drer\slc6a6b, Drer\slc6a17, Drer\zgc:158225, Drer\slc6a19b, Drer\zgc:174946, Drer\slc6a2, Drer\slc6a13, Drer\slc6a4a, Drer\slc6a4b, Drer\slc6a18, Drer\slc6a1a, Drer\slc6a6a, Drer\slc6a1b, Drer\si:ch211-117c9.5, Drer\si:ch211-132b12.3, Drer\slc6a14, Drer\si:ch211-132b12.6, Drer\slc6a13l, Drer\slc6a9, Drer\slc6a8" - "Cele\snf-12, Cele\snf-5, Cele\snf-7, Cele\snf-9, Cele\snf-2, Cele\snf-11, Cele\dat-1, Cele\mod-5, Cele\snf-6, Cele\snf-3" "Xtro\slc6a7, Xtro\slc6a9, Xtro\slc6a2, Xtro\slc6a3, Xtro\slc6a14.2, Xtro\slc6a8, Xtro\slc6a19, Xtro\slc6a17, Xtro\slc6a1, Xtro\slc6a13, Xtro\slc6a15, Xtro\slc6a5, Xtro\slc6a12, Xtro\LOC100127682, Xtro\slc6a6, Xtro\slc6a4, Xtro\slc6a16" "Mmus\Slc6a2, Mmus\Slc6a5, Mmus\Slc6a1, Mmus\Slc6a7, Mmus\Slc6a3, Mmus\Slc6a13, Mmus\Slc6a19, Mmus\Slc6a6, Mmus\Slc6a17, Mmus\Slc6a15, Mmus\Slc6a12, Mmus\Slc6a9, Mmus\Slc6a8, Mmus\Slc6a18, Mmus\Slc6a20b, Mmus\Slc6a11, Mmus\Slc6a14, Mmus\Slc6a20a, Mmus\Slc6a4" "Hsap\SLC6A5, Hsap\SLC6A9, Hsap\SLC6A17, Hsap\SLC6A20, Hsap\SLC6A19, Hsap\SLC6A8, Hsap\SLC6A2, Hsap\SLC6A13, Hsap\SLC6A18, Hsap\SLC6A12, Hsap\SLC6A15, Hsap\SLC6A14, Hsap\SLC6A3, Hsap\SLC6A11, Hsap\SLC6A6, Hsap\SLC6A1, Hsap\SLC6A4" viable FBgn0003705 ti tarsi irregular http://flybase.org/reports/FBgn0003705 - gene - - - ti - - 27-Aug-18 DroID_v2018_08 - - - - - - partially lethal - majority live "eye,tarsal segment 3,tarsal segment 4" FBgn0035152 CG3386 - http://flybase.org/reports/FBgn0035152 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG3386 IPR006578:MADF domain CG3386 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" FBgn0267031 lncRNA:CR45475 - http://flybase.org/reports/FBgn0267031 non_protein_coding_gene - - - CR45475 - CR45475 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060356 l(3)S140901 lethal (3) S140901 http://flybase.org/reports/FBgn0060356 gene - - - "1409/01, l(3)S140901" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0035852 CG7387 - http://flybase.org/reports/FBgn0035852 protein_coding_gene "unfolded protein binding ; GO:0051082 | inferred from electronic annotation with InterPro:IPR001305, InterPro:IPR008971 heat shock protein binding ; GO:0031072 | inferred from electronic annotation with InterPro:IPR001305" protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR008971 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN001531327 "anon-WO0140519.72, CG7387" "IPR001305:Heat shock protein DnaJ, cysteine-rich domain, IPR001623:DnaJ domain, IPR002939:Chaperone DnaJ, C-terminal, IPR008971:HSP40/DnaJ peptide-binding, IPR018253:DnaJ domain, conserved site" CG7387 27-Aug-18 DroID_v2018_08 "Drer\dnaja3b, Drer\dnajc16l, Drer\dnajc16, Drer\dnaja3a, Drer\dnaja1, Drer\dnajc24" "Scer\SCJ1, Scer\YDJ1, Scer\MDJ1" "Cele\dnj-14, Cele\dnj-10, Cele\dnj-8, Cele\dnj-3" "Xtro\dnajc24, Xtro\dnajc16" "Mmus\Dnaja1, Mmus\Dnajc24, Mmus\Dnaja3, Mmus\Dnaja4, Mmus\Dnajc16" "Hsap\DNAJA1, Hsap\DNAJA4, Hsap\DNAJA3, Hsap\DNAJC16, Hsap\DNAJC24" "partially lethal - majority die,some die during pupal stage" FBgn0035541 CG15019 - http://flybase.org/reports/FBgn0035541 protein_coding_gene - - - CG15019 IPR018784:Learning associated protein 18-like CG15019 27-Aug-18 DroID_v2018_08 Drer\llph - Cele\C49H3.3 Xtro\llph Mmus\Llph Hsap\LLPH viable FBgn0027180 l(2)60A-N lethal (2) 60A-N http://flybase.org/reports/FBgn0027180 - gene - - - l(2)60A-N - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0065117 l(3)SH158 lethal (3) SH158 http://flybase.org/reports/FBgn0065117 gene - - - "l(3)SH158, l(2)SH3 158" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0003226 re-b reduced eyes b http://flybase.org/reports/FBgn0003226 - gene - - - re-b - - 27-Aug-18 DroID_v2018_08 - - - - - - "ommatidium,eye" FBgn0060535 l(3)S100502b lethal (3) S100502b http://flybase.org/reports/FBgn0060535 gene - - - "1005/02, l(3)S100502b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0013681 mt:ND3 mitochondrial NADH-ubiquinone oxidoreductase chain 3 http://flybase.org/reports/FBgn0013681 FBgn0002867 protein_coding_gene NADH dehydrogenase (ubiquinone) activity ; GO:0008137 | inferred from electronic annotation with InterPro:IPR000440 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000440 - "CG34076, ND3, NADH3, URF3, mt:ND3, nad3" "IPR000440:NADH:ubiquinone/plastoquinone oxidoreductase, chain 3" CG34076 27-Aug-18 DroID_v2018_08 Drer\ND3 - Cele\ND3 Xtro\ND3 Mmus\ND3 Hsap\ND3 FBgn0041092 tai taiman http://flybase.org/reports/FBgn0041092 protein_coding_gene protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 ligand-dependent nuclear receptor transcription coactivator activity ; GO:0030374 | inferred from direct assay steroid hormone receptor binding ; GO:0035258 | inferred from physical interaction with EcR ligand-dependent nuclear receptor binding ; GO:0016922 | inferred from biological aspect of ancestor with PANTHER:PTN000074430 "positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from biological aspect of ancestor with PANTHER:PTN000074430 intracellular receptor signaling pathway ; GO:0030522 | inferred from biological aspect of ancestor with PANTHER:PTN000074430 border follicle cell migration ; GO:0007298 | inferred from mutant phenotype positive regulation of growth ; GO:0045927 | inferred from mutant phenotype germ-line stem-cell niche homeostasis ; GO:0060250 | inferred from mutant phenotype axon extension ; GO:0048675 | inferred from mutant phenotype cellular response to hormone stimulus ; GO:0032870 | inferred from biological aspect of ancestor with PANTHER:PTN000074430 regulation of transcription, DNA-templated ; GO:0006355 | inferred from sequence or structural similarity with tgo" ecdysone receptor holocomplex ; GO:0008230 | colocalizes_with inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "DAIB1, DmTaiman, CG13109, l(2)k05809, EP(2)2630, l(2)01351, 58/2, l(2)k05802, bs13g05.y1, TAI, NEST:bs13g05, CG18494, tai, Tai" "IPR000014:PAS domain, IPR011989:Armadillo-like helical, IPR015943:WD40/YVTN repeat-like-containing domain, IPR017426:Nuclear receptor coactivator, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG13109 27-Aug-18 DroID_v2018_08 "Drer\arntl1b, Drer\ncoa1, Drer\clockb, Drer\ncoa2, Drer\ncoa3, Drer\arntl1a" - - "Xtro\arntl, Xtro\ncoa2" "Mmus\Clock, Mmus\Arntl2, Mmus\Ncoa1, Mmus\Arntl, Mmus\Ncoa2, Mmus\Ncoa3" "Hsap\NCOA2, Hsap\ARNTL2, Hsap\NCOA1, Hsap\NCOA3, Hsap\ARNTL" adult stage follicle cell

"neuroanatomy defective,somatic clone,lethal,recessive,maternal effect,sleep defective,lethal - all die before end of pupal stage,some die during pupal stage,smell perception defective,female limited,gravitaxis defective" "axon | somatic clone | third instar larval stage,border follicle cell,female germline stem cell,supernumerary,somatic clone,imaginal disc,germarium cap cell,embryonic/first instar larval cuticle,maternal effect,escort stem cell,germline cell,heat sensitive" FBgn0034707 MED16 Mediator complex subunit 16 http://flybase.org/reports/FBgn0034707 protein_coding_gene RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from direct assay transcription coactivator activity ; GO:0003713 | inferred from biological aspect of ancestor with PANTHER:PTN000996461 RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from sequence or structural similarity "response to heat ; GO:0009408 | inferred from mutant phenotype transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity response to lipopolysaccharide ; GO:0032496 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from biological aspect of ancestor with PANTHER:PTN000996461 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from direct assay" mediator complex ; GO:0016592 | inferred from direct assay mediator complex ; GO:0016592 | inferred from biological aspect of ancestor with PANTHER:PTN000996461 mediator complex ; GO:0016592 | inferred from sequence or structural similarity "Trap95, Med16, CG5465, Sin4/TRAP95, dTRAP95, MED16, med16" "IPR017986:WD40-repeat-containing domain, IPR021665:Mediator complex, subunit Med16, IPR015943:WD40/YVTN repeat-like-containing domain" CG5465 27-Aug-18 DroID_v2018_08 Drer\med16 - - Xtro\med16 Mmus\Med16 Hsap\MED16 viable DRSC26633 EK -0.216323112 -0.212411918 -1.604794216 0.820954838 1.223349538 3.473917134 FBgn0038219 CG14839 - http://flybase.org/reports/FBgn0038219 protein_coding_gene molecular_function ; GO:0003674 | no biological data available developmental process ; GO:0032502 | inferred from biological aspect of ancestor with PANTHER:PTN002201458 cellular_component ; GO:0005575 | no biological data available CG14839 IPR007999:Protein of unknown function DUF745 CG14839 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002391 l(3)93Dh lethal (3) 93Dh http://flybase.org/reports/FBgn0002391 - gene - - - "er16, l(3)er16, l(3)93Dh" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0038972 CG7054 - http://flybase.org/reports/FBgn0038972 protein_coding_gene - - - CG7054 IPR008914:Phosphatidylethanolamine-binding protein CG7054 27-Aug-18 DroID_v2018_08 "Drer\mrpl38, Drer\pebp1" "Scer\MRPL35, Scer\YLR179C, Scer\TFS1" "Cele\F40A3.3, Cele\Y69E1A.5" "Xtro\mrpl38, Xtro\pebp4, Xtro\pebp1" "Mmus\Mrpl38, Mmus\Pbp2, Mmus\Pebp1, Mmus\Pebp4" "Hsap\PEBP1, Hsap\PEBP4, Hsap\MRPL38" "viable,visible" trichogen cell DRSC16185 K 0.026247332 0.174391091 0.392094207 0.43711184 0.421263102 1.78836673 FBgn0004450 stripes stripes http://flybase.org/reports/FBgn0004450 - gene - - - "stripes, str" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260298 GSd416 - http://flybase.org/reports/FBgn0260298 gene - - - GSd416 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0023537 CG17896 - http://flybase.org/reports/FBgn0023537 - protein_coding_gene methylmalonate-semialdehyde dehydrogenase (acylating) activity ; GO:0004491 | inferred from sequence or structural similarity with UniProtKB:Q02252 fatty-acyl-CoA binding ; GO:0000062 | inferred from sequence or structural similarity with UniProtKB:Q07536 methylmalonate-semialdehyde dehydrogenase (acylating) activity ; GO:0004491 | inferred from sequence or structural similarity with UniProtKB:Q02253 malonate-semialdehyde dehydrogenase (acetylating) activity ; GO:0018478 | inferred from sequence or structural similarity with UniProtKB:Q02253 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR010061, InterPro:IPR015590, InterPro:IPR016160, InterPro:IPR016161, InterPro:IPR016162, InterPro:IPR016163 valine metabolic process ; GO:0006573 | inferred from sequence or structural similarity with UniProtKB:Q02252 thymine metabolic process ; GO:0019859 | inferred from sequence or structural similarity with UniProtKB:Q02253 valine metabolic process ; GO:0006573 | inferred from sequence or structural similarity with UniProtKB:Q02253 pyrimidine nucleobase metabolic process ; GO:0006206 | inferred from sequence or structural similarity with UniProtKB:Q02252" mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q02252 "153323_at, EG:171D11.1, CG17896" "IPR010061:Methylmalonate-semialdehyde dehydrogenase, IPR015590:Aldehyde dehydrogenase domain, IPR016160:Aldehyde dehydrogenase, cysteine active site, IPR016161:Aldehyde/histidinol dehydrogenase, IPR016162:Aldehyde dehydrogenase N-terminal domain, IPR034323:Methylmalonate semialdehyde dehydrogenase, mitochondrial" CG17896 27-Aug-18 DroID_v2018_08 Drer\aldh6a1 "Scer\ALD5, Scer\ALD2, Scer\ALD6" Cele\alh-8 Xtro\aldh6a1 Mmus\Aldh6a1 Hsap\ALDH6A1 viable DRSC18502 E 1.240730039 0.352853847 1.96410679 0.21719568 0.643696859 0.498358802 FBgn0267289 lncRNA:CR45725 - http://flybase.org/reports/FBgn0267289 non_protein_coding_gene - - - CR45725 - CR45725 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264787 lncRNA:CR44017 - http://flybase.org/reports/FBgn0264787 non_protein_coding_gene - - - CR44017 - CR44017 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0062578 Mod(var)E1047 Mod(var)E1047 http://flybase.org/reports/FBgn0062578 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "E1047, Mod(var)E1047" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,enhancer of variegation,non-enhancer of variegation,non-suppressor of variegation" FBgn0266452 CTPsyn CTP synthase http://flybase.org/reports/FBgn0266452 protein_coding_gene CTP synthase activity ; GO:0003883 | inferred from sequence or structural similarity with HGNC:2519 CTP synthase activity ; GO:0003883 | inferred from sequence or structural similarity with UniProtKB:P17812 CTP biosynthetic process ; GO:0006241 | inferred from sequence or structural similarity with HGNC:2519 CTP biosynthetic process ; GO:0006241 | inferred from sequence or structural similarity with UniProtKB:P17812 neurogenesis ; GO:0022008 | inferred from mutant phenotype larval lymph gland hemopoiesis ; GO:0035167 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay cytoophidium ; GO:0097268 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "CG6854, CTPsyn, CG45070, CTPS" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR004468:CTP synthase, IPR017456:CTP synthase, N-terminal, IPR017926:Glutamine amidotransferase, IPR033828:CTP synthase GATase domain, IPR029062:Class I glutamine amidotransferase-like" CG45070 27-Aug-18 DroID_v2018_08 "Drer\ctps1a, Drer\ctps1b" "Scer\URA7, Scer\URA8" Cele\ctps-1 "Xtro\ctps1, Xtro\ctps2" "Mmus\Ctps, Mmus\Ctps2" "Hsap\CTPS2, Hsap\CTPS1" "lethal,recessive,small body,developmental rate defective,majority die during larval stage,neuroanatomy defective,viable" "cytoophidiumnos.UTR.THsimVP16,egg chamber,cytoophidiumAct.PU,follicle cell,cytoophidium | cell autonomous | somatic clonetub.PU,cell autonomous,somatic clone,cytoophidium | somatic clonetub.PU,cytoophidium | germline clone,germline clone,ganglion mother cell,embryonic/larval neuroblast" FBgn0010079 Rst(2)mth Resistance to malathion on chromosome 2 http://flybase.org/reports/FBgn0010079 - gene - - - Rst(2)mth - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260608 2L2938 - http://flybase.org/reports/FBgn0260608 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L2938 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0266814 lncRNA:CR45276 - http://flybase.org/reports/FBgn0266814 non_protein_coding_gene - - - CR45276 - CR45276 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0261269 conv convoluted http://flybase.org/reports/FBgn0261269 protein_coding_gene transmembrane signaling receptor activity ; GO:0004888 | inferred from electronic annotation with InterPro:IPR027176 "toll-like receptor 5 signaling pathway ; GO:0034146 | inferred from electronic annotation with InterPro:IPR027176 MyD88-dependent toll-like receptor signaling pathway ; GO:0002755 | inferred from electronic annotation with InterPro:IPR027176 positive regulation of cytokine production ; GO:0001819 | inferred from electronic annotation with InterPro:IPR027176 regulation of cytokine secretion ; GO:0050707 | inferred from electronic annotation with InterPro:IPR027176 defense response to bacterium ; GO:0042742 | inferred from electronic annotation with InterPro:IPR027176 motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from mutant phenotype regulation of tube length, open tracheal system ; GO:0035159 | inferred from mutant phenotype regulation of tube size, open tracheal system ; GO:0035151 | inferred from mutant phenotype" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR027176 "conv, CG8561, dALS, l(2)k06507b, Als, tartan/capricious-like, CT24963, ALS" "IPR032675:Leucine-rich repeat domain, L domain-like, IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR026906:Leucine rich repeat 5, IPR027176:Toll-like receptor 5" CG8561 27-Aug-18 DroID_v2018_08 "Drer\tlr9, Drer\nyx, Drer\igfals, Drer\si:dkey-182i3.11" - Cele\lron-15 Xtro\nyx "Mmus\Tlr7, Mmus\Tlr3, Mmus\Tlr9, Mmus\Tlr5, Mmus\Tlr8, Mmus\Igfals, Mmus\Nyx" "Hsap\NYX, Hsap\IGFALS, Hsap\TLR5" FBgn0014147 dh double halteres http://flybase.org/reports/FBgn0014147 - gene - - - dh - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033653 CG13192 - http://flybase.org/reports/FBgn0033653 protein_coding_gene molecular_function ; GO:0003674 | no biological data available social behavior ; GO:0035176 | inferred from sequence or structural similarity with MGI:MGI:1338057 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with MGI:MGI:1338057 CG13192 "IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR019775:WD40 repeat, conserved site" CG13192 27-Aug-18 DroID_v2018_08 Drer\gnb1l - "Cele\C10B5.1, Cele\mec-15" Xtro\gnb1l Mmus\Gnb1l Hsap\GNB1L viable FBgn0035353 CG18334 - http://flybase.org/reports/FBgn0035353 protein_coding_gene - - - CG18334 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031887 CG11289 - http://flybase.org/reports/FBgn0031887 protein_coding_gene "transferase activity, transferring hexosyl groups ; GO:0016758 | inferred from electronic annotation with InterPro:IPR002213 UDP-glycosyltransferase activity ; GO:0008194 | inferred from biological aspect of ancestor with PANTHER:PTN000230403" metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR002213 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000230403 CG11289 IPR002213:UDP-glucuronosyl/UDP-glucosyltransferase CG11289 27-Aug-18 DroID_v2018_08 "Drer\ugt1b2, Drer\ugt5f1, Drer\zgc:172315, Drer\ugt5b1, Drer\ugt5a1, Drer\ugt5b3, Drer\ugt5b2, Drer\ugt5b6, Drer\ugt5c2, Drer\ugt5g1, Drer\ugt5d1, Drer\ugt5c1, Drer\ugt2a2, Drer\ugt2a5, Drer\ugt1ab, Drer\ugt1b3, Drer\ugt5g2, Drer\ugt1b4, Drer\ugt5a2, Drer\ugt2b5, Drer\ugt5c3, Drer\ugt2b6, Drer\ugt1b7, Drer\ugt2b3, Drer\ugt8, Drer\ugt2a6, Drer\ugt5a4, Drer\ugt5e1, Drer\ugt1b5, Drer\ugt2b1, Drer\ugt5a5" Scer\ATG26 "Cele\C03A7.12, Cele\ugt-35, Cele\ugt-27, Cele\ugt-22, Cele\ugt-30, Cele\ugt-23, Cele\ugt-28, Cele\ugt-13, Cele\ugt-51, Cele\ugt-65, Cele\ugt-38, Cele\ugt-25, Cele\ugt-14, Cele\ugt-57, Cele\ugt-5, Cele\ugt-31, Cele\ugt-20, Cele\ugt-4, Cele\ugt-9, Cele\ugt-39, Cele\ugt-11, Cele\ugt-10, Cele\ugt-15, Cele\ugt-62, Cele\ugt-7, Cele\ugt-42, Cele\ugt-17, Cele\ugt-37, Cele\ugt-44, Cele\ugt-58, Cele\ugt-34, Cele\ugt-36, Cele\ugt-53, Cele\ugt-61, Cele\ugt-6, Cele\ugt-2, Cele\ugt-45, Cele\ugt-3, Cele\C55H1.1, Cele\ugt-55, Cele\ugt-19, Cele\ugt-26, Cele\ugt-52, Cele\ugt-1, Cele\ugt-24, Cele\ugt-18, Cele\ugt-29, Cele\K04A8.10, Cele\ugt-48, Cele\ugt-43, Cele\ugt-47, Cele\ugt-50, Cele\ugt-59, Cele\Y43D4A.2, Cele\C03A7.13, Cele\C23G10.6, Cele\ugt-32, Cele\ugt-21, Cele\ugt-60, Cele\ugt-54, Cele\ugt-41, Cele\ugt-16, Cele\H23N18.4, Cele\ugt-33, Cele\F10D2.8, Cele\ugt-56, Cele\ugt-12, Cele\ugt-49, Cele\ugt-46, Cele\ugt-8, Cele\ugt-40" "Xtro\ugt2a1, Xtro\ugt1a6, Xtro\ugt2b4, Xtro\ugt3a2, Xtro\ugt8" "Mmus\Ugt2a3, Mmus\Ugt3a1, Mmus\Ugt1a5, Mmus\Ugt1a9, Mmus\Ugt2b1, Mmus\Ugt1a1, Mmus\Ugt2b5, Mmus\Ugt1a6b, Mmus\Ugt1a2, Mmus\Ugt2b35, Mmus\Ugt3a2, Mmus\Ugt2b34, Mmus\Ugt2b38, Mmus\Ugt2a1, Mmus\Ugt1a7c, Mmus\Ugt8a, Mmus\Ugt2b36, Mmus\Ugt2b37" "Hsap\UGT2B11, Hsap\UGT2A3, Hsap\UGT1A10, Hsap\UGT8, Hsap\UGT1A4, Hsap\UGT2B4, Hsap\UGT1A9, Hsap\UGT2B7, Hsap\UGT3A1, Hsap\UGT2B17, Hsap\UGT1A5, Hsap\UGT1A6, Hsap\UGT1A3, Hsap\UGT2B28, Hsap\UGT1A1, Hsap\UGT2A2, Hsap\UGT1A7, Hsap\UGT1A8, Hsap\UGT3A2, Hsap\UGT2B15, Hsap\UGT2B10" "viable,visible" mesothoracic tergum FBgn0022014 l(2)k09035 lethal (2) k09035 http://flybase.org/reports/FBgn0022014 - gene - - - l(2)k09035 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0021766 s3754 s3754 http://flybase.org/reports/FBgn0021766 - gene - - - s3754 - - 27-Aug-18 DroID_v2018_08 - - - - - - chemical sensitive FBgn0265351 nac neuronally altered carbohydrate http://flybase.org/reports/FBgn0265351 protein_coding_gene UDP-galactose transmembrane transporter activity ; GO:0005459 | NOT inferred from direct assay GDP-fucose transmembrane transporter activity ; GO:0005457 | inferred from direct assay UDP-N-acetylgalactosamine transmembrane transporter activity ; GO:0005463 | NOT inferred from direct assay UDP-N-acetylglucosamine transmembrane transporter activity ; GO:0005462 | NOT inferred from direct assay GDP-mannose transmembrane transporter activity ; GO:0005458 | NOT inferred from direct assay CMP-N-acetylneuraminate transmembrane transporter activity ; GO:0005456 | NOT inferred from direct assay UDP-glucuronic acid transmembrane transporter activity ; GO:0005461 | NOT inferred from direct assay UDP-glucose transmembrane transporter activity ; GO:0005460 | NOT inferred from direct assay GDP-fucose transmembrane transporter activity ; GO:0005457 | inferred from mutant phenotype "Golgi vesicle transport ; GO:0048193 | inferred from direct assay UDP-glucuronic acid transport ; GO:0015787 | NOT inferred from direct assay CMP-N-acetylneuraminate transport ; GO:0015782 | NOT inferred from direct assay GDP-fucose transport ; GO:0015783 | inferred from direct assay protein O-linked fucosylation ; GO:0036066 | inferred from mutant phenotype grooming behavior ; GO:0007625 | inferred from mutant phenotype N-glycan fucosylation ; GO:0036071 | inferred from mutant phenotype UDP-N-acetylglucosamine transport ; GO:0015788 | NOT inferred from direct assay GDP-fucose import into Golgi lumen ; GO:0036085 | inferred by curator from GO:0005457,GO:0005794 UDP-galactose transport ; GO:0015785 | NOT inferred from direct assay GDP-mannose transport ; GO:0015784 | NOT inferred from direct assay UDP-N-acetylgalactosamine transport ; GO:0015789 | NOT inferred from direct assay GDP-fucose import into Golgi lumen ; GO:0036085 | inferred from direct assay inferred from mutant phenotype UDP-glucose transport ; GO:0015786 | NOT inferred from direct assay" Golgi apparatus ; GO:0005794 | inferred from direct assay Golgi-associated vesicle ; GO:0005798 | inferred from direct assay "Gfr, nac, gfr, CG9620, Nac" IPR004853:Sugar phosphate transporter domain CG9620 27-Aug-18 DroID_v2018_08 Drer\slc35c1 - "Cele\nstp-10, Cele\nstp-9" Xtro\slc35c1 Mmus\Slc35c1 Hsap\SLC35C1 FBgn0000361 Cp70 Chorion protein 70 http://flybase.org/reports/FBgn0000361 - gene structural constituent of chorion ; GO:0005213 | inferred from direct assay eggshell chorion assembly ; GO:0007306 | inferred from direct assay - "s70, Cp70" - - 27-Aug-18 DroID_v2018_08 - - - - - - electrophoretic variant FBgn0030008 CG2129 - http://flybase.org/reports/FBgn0030008 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - heterochromatin ; GO:0000792 | inferred from direct assay CG2129 "IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG2129 27-Aug-18 DroID_v2018_08 "Drer\hic1l, Drer\gb:ai877918, Drer\si:dkey-7l6.3, Drer\si:ch73-138e16.2, Drer\LOC101882465, Drer\LOC101886047, Drer\zbtb43" Scer\AZF1 "Cele\pag-3, Cele\hinf-1, Cele\Y55F3AM.14, Cele\blmp-1" - "Mmus\Zfp276, Mmus\Zscan10, Mmus\Zfp775, Mmus\Zbtb43, Mmus\Zfp653" "Hsap\ZNF775, Hsap\ZNF276, Hsap\ZBTB43, Hsap\ZNF653, Hsap\ZSCAN10, Hsap\ZNF677, Hsap\ZNF614" FBgn0058092 CG40092 - http://flybase.org/reports/FBgn0058092 protein_coding_gene - - - CG40092 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0015876 anon-48Ae anon-48Ae http://flybase.org/reports/FBgn0015876 - gene - - - "VII, anon-48Ae" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262435 mir-1009 mir-1009 stem loop http://flybase.org/reports/FBgn0262435 miRNA_gene - - - "dme-mir-1009, miR-1009, mir-1009, CR42994" - CR42994 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0083269 E(smoDN)390 Enhancer of smoDN 390 http://flybase.org/reports/FBgn0083269 gene - - - E(smoDN)390 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0016041 Tom40 Translocase of outer membrane 40 http://flybase.org/reports/FBgn0016041 "FBgn0027267, FBgn0029960" protein_coding_gene protein channel activity ; GO:0015266 | inferred from biological aspect of ancestor with PANTHER:PTN000085854 P-P-bond-hydrolysis-driven protein transmembrane transporter activity ; GO:0015450 | inferred from sequence or structural similarity with UniProtKB:O96008 protein targeting to mitochondrion ; GO:0006626 | inferred from sequence or structural similarity with UniProtKB:O96008 protein targeting to mitochondrion ; GO:0006626 | inferred from sequence or structural similarity with UniProtKB:Q75Q40 cellular response to hypoxia ; GO:0071456 | inferred from mutant phenotype protein import into mitochondrial matrix ; GO:0030150 | inferred from biological aspect of ancestor with PANTHER:PTN000085854 mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial outer membrane translocase complex ; GO:0005742 | inferred from biological aspect of ancestor with PANTHER:PTN000085854 mitochondrial outer membrane translocase complex ; GO:0005742 | inferred from sequence or structural similarity with UniProtKB:O96008 "CG12157, dtom40, mit, ms15, l(1)G0216, ms(1)15, Tom40, tom40" IPR027246:Eukaryotic porin/Tom40 CG12157 27-Aug-18 DroID_v2018_08 "Drer\tomm40l, Drer\si:dkey-71l1.1, Drer\tomm40" Scer\TOM40 Cele\tomm-40 "Xtro\tomm40, Xtro\tomm40l" "Mmus\Tomm40, Mmus\Tomm40l" "Hsap\TOMM40L, Hsap\TOMM40" "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0263334 lncRNA:CR43415 - http://flybase.org/reports/FBgn0263334 non_protein_coding_gene - - - "CR43415, lincRNA.319" - CR43415 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0027304 l(1)G0121 lethal (1) G0121 http://flybase.org/reports/FBgn0027304 - gene - - - l(1)G0121 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,partially lethal - majority die,recessive" FBgn0041211 H23-14 H23-14 http://flybase.org/reports/FBgn0041211 gene - - - H23-14 - - 27-Aug-18 DroID_v2018_08 - - - - - - auxotroph FBgn0033591 CG13216 - http://flybase.org/reports/FBgn0033591 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13216 - CG13216 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0000830 fs(1)M11 female sterile (1) M11 http://flybase.org/reports/FBgn0000830 - gene - - - fs(1)M11 - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive,lethal,maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage" egg FBgn0040127 l(2)23CDa lethal (2) 23CDa http://flybase.org/reports/FBgn0040127 gene - - - l(2)23CDa - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0010934 l(3)09291 lethal (3) 09291 http://flybase.org/reports/FBgn0010934 - gene - - - "P1736, l(3)09291" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0038640 CG7706 - http://flybase.org/reports/FBgn0038640 protein_coding_gene mRNA binding ; GO:0003729 | inferred from biological aspect of ancestor with PANTHER:PTN002359305 - - CG7706 "IPR000253:Forkhead-associated (FHA) domain, IPR008984:SMAD/FHA domain" CG7706 27-Aug-18 DroID_v2018_08 Drer\slc4a1ap - Cele\ZK632.2 Xtro\slc4a1ap Mmus\Slc4a1ap Hsap\SLC4A1AP viable FBgn0053818 His3:CG33818 His3:CG33818 http://flybase.org/reports/FBgn0053818 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 nucleosomal DNA binding ; GO:0031492 | inferred from sequence or structural similarity with UniProtKB:P84243 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P84243 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:P84243 "CG33818, His3:CG33818" "IPR000164:Histone H3/CENP-A, IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3" CG33818 27-Aug-18 DroID_v2018_08 "Drer\h3f3c, Drer\cenpa, Drer\h3f3d, Drer\hist2h3ca1, Drer\si:ch73-36p18.2, Drer\h3f3a, Drer\LOC108190746, Drer\si:ch1073-429i10.3, Drer\si:dkey-23a13.8, Drer\zgc:173552, Drer\hist2h3c, Drer\zgc:113984, Drer\LOC108190747, Drer\zgc:113983, Drer\h3f3b.1" "Scer\CSE4, Scer\HHT2, Scer\HHT1" "Cele\his-63, Cele\his-74, Cele\his-71, Cele\his-69, Cele\his-13, Cele\his-25, Cele\his-42, Cele\his-32, Cele\his-72, Cele\his-49, Cele\his-27, Cele\his-59, Cele\his-6, Cele\his-2, Cele\his-9, Cele\his-17, Cele\his-55, Cele\his-45" "Xtro\cenpa, Xtro\h3f3b, Xtro\hist2h3d" "Mmus\H3f3b, Mmus\Hist1h3d, Mmus\Hist1h3i, Mmus\Cenpa, Mmus\Hist1h3h, Mmus\Hist2h3b, Mmus\Hist1h3c, Mmus\Hist1h3b, Mmus\Hist1h3a, Mmus\Hist1h3e, Mmus\Hist2h3c1, Mmus\H3f3a, Mmus\Hist1h3f, Mmus\Hist2h3c2, Mmus\Hist1h3g" "Hsap\HIST2H3D, Hsap\HIST1H3C, Hsap\HIST3H3, Hsap\HIST1H3J, Hsap\CENPA, Hsap\H3F3B, Hsap\H3F3C, Hsap\H3F3A, Hsap\HIST2H3A, Hsap\HIST1H3F, Hsap\HIST1H3E, Hsap\HIST1H3D, Hsap\HIST1H3A, Hsap\HIST2H3C, Hsap\HIST1H3G, Hsap\HIST1H3I, Hsap\HIST1H3B, Hsap\HIST1H3H" FBgn0002523 lacquered lacquered http://flybase.org/reports/FBgn0002523 - gene - - - "lac, lacquered" - - 27-Aug-18 DroID_v2018_08 - - - - - - "fertile,reduced,viable,eye color defective,body color defective,visible,recessive" "macrochaeta,eye,wing" FBgn0264724 lncRNA:CR43992 - http://flybase.org/reports/FBgn0264724 non_protein_coding_gene - - - "CR43992, lincRNA.567" - CR43992 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060303 l(3)SzB87Da lethal (3) SzB87Da http://flybase.org/reports/FBgn0060303 gene - - - "1132/08, 0098/05, 0074/03, l(3)SzB87Da" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0039088 CG10164 - http://flybase.org/reports/FBgn0039088 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs02f09, CG10164" - CG10164 27-Aug-18 DroID_v2018_08 - - - - - - "neuroanatomy defective,viable" "mushroom body & axon7B,Kenyon cell" FBgn0010071 Ma-dominigene Ma dominigene http://flybase.org/reports/FBgn0010071 - gene - - - "Ma-dominigene, Ma" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030581 CG14408 - http://flybase.org/reports/FBgn0030581 protein_coding_gene SH3 domain binding ; GO:0017124 | inferred from biological aspect of ancestor with PANTHER:PTN001066235 protein kinase inhibitor activity ; GO:0004860 | inferred from biological aspect of ancestor with PANTHER:PTN001066235 negative regulation of protein tyrosine kinase activity ; GO:0061099 | inferred from biological aspect of ancestor with PANTHER:PTN001066235 intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN001066235 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001066235 CG14408 IPR007940:SH3-binding 5 CG14408 27-Aug-18 DroID_v2018_08 "Drer\sh3bp5b, Drer\sh3bp5lb, Drer\sh3bp5la, Drer\sh3bp5a, Drer\LOC103909186" - "Cele\rei-2, Cele\rei-1" "Xtro\sh3bp5, Xtro\sh3bp5l" "Mmus\Sh3bp5l, Mmus\Sh3bp5" "Hsap\SH3BP5L, Hsap\SH3BP5" FBgn0000937 fs(2)A7 female sterile (2) A7 http://flybase.org/reports/FBgn0000937 - gene - - - fs(2)A7 - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive,mitotic cell cycle defective" female reproductive system FBgn0060432 l(3)S125815 lethal (3) S125815 http://flybase.org/reports/FBgn0060432 gene - - - "1258/15, l(3)S125815" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0016848 l(1)N29 lethal (1) N29 http://flybase.org/reports/FBgn0016848 - gene - - - "l(1)N29, N29" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0262620 lncRNA:CR43144 - http://flybase.org/reports/FBgn0262620 non_protein_coding_gene - - - "CR43144, CG43144, lincRNA.217" - CR43144 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051627 CG31627 - http://flybase.org/reports/FBgn0051627 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN001073606 transcription coactivator activity ; GO:0003713 | inferred from biological aspect of ancestor with PANTHER:PTN001073606 basal RNA polymerase II transcription machinery binding ; GO:0001099 | inferred from biological aspect of ancestor with PANTHER:PTN001073606" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from biological aspect of ancestor with PANTHER:PTN001073606" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001073606 "NEST:bs05g10, CG31627" IPR006578:MADF domain CG31627 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,some die during pupal stage" FBgn0030653 CG7860 - http://flybase.org/reports/FBgn0030653 protein_coding_gene asparaginase activity ; GO:0004067 | inferred from electronic annotation with InterPro:IPR033844 salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern asparagine catabolic process via L-aspartate ; GO:0033345 | inferred from sequence or structural similarity with UniProtKB:Q8VI04 autophagic cell death ; GO:0048102 | inferred from expression pattern cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:Q8VI04 CG7860 "IPR000246:Peptidase T2, asparaginase 2, IPR033844:Asparaginase-like 1, metazoa, IPR029055:Nucleophile aminohydrolases, N-terminal" CG7860 27-Aug-18 DroID_v2018_08 "Drer\zgc:153169, Drer\si:dkey-103j14.5, Drer\tasp1, Drer\asrgl1, Drer\si:ch211-256m1.8" - Cele\K01G5.9 "Xtro\tasp1, Xtro\LOC100486129, Xtro\asrgl1" "Mmus\Asrgl1, Mmus\Tasp1" "Hsap\ASRGL1, Hsap\TASP1" "viable,lethal" FBgn0265516 Atal Atal http://flybase.org/reports/FBgn0265516 gene - - - Atal - - 27-Aug-18 DroID_v2018_08 - - - - - - "female semi-sterile,dominant,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0015941 fs(3)820 fs(3)820 http://flybase.org/reports/FBgn0015941 - gene - - - fs(3)820 - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,mitotic cell cycle defective" FBgn0036831 CG6839 - http://flybase.org/reports/FBgn0036831 protein_coding_gene "hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR020821 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR020821 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR020821" apoptotic DNA fragmentation ; GO:0006309 | inferred from biological aspect of ancestor with PANTHER:PTN000359601 - CG6839 "IPR001604:DNA/RNA non-specific endonuclease, IPR020821:Extracellular Endonuclease, subunit A" CG6839 27-Aug-18 DroID_v2018_08 "Drer\LOC103910196, Drer\endog, Drer\si:ch211-133n4.4, Drer\LOC100333474" Scer\NUC1 Cele\cps-6 - Mmus\Endog Hsap\ENDOG viable FBgn0016033 lnp larval nonphototactic http://flybase.org/reports/FBgn0016033 - gene - - - "lnp, Lnp" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065449 l(2)SH1404 lethal (2) SH1404 http://flybase.org/reports/FBgn0065449 gene - - - "l(2)SH1404, l(2)SH2 1404" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0265924 lncRNA:CR44713 - http://flybase.org/reports/FBgn0265924 non_protein_coding_gene - - - CR44713 - CR44713 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0027146 l(3)71DEa lethal (3) 71DEa http://flybase.org/reports/FBgn0027146 - gene - - - l(3)71DEa - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0053653 Cadps Calcium-dependent secretion activator http://flybase.org/reports/FBgn0053653 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from sequence or structural similarity with UniProtKB:Q62717 "dense core granule exocytosis ; GO:1990504 | inferred from electronic annotation with InterPro:IPR033227 synaptic vesicle exocytosis ; GO:0016079 | inferred from mutant phenotype neurotransmitter secretion ; GO:0007269 | non-traceable author statement positive regulation of calcium ion-dependent exocytosis ; GO:0045956 | inferred from sequence or structural similarity with UniProtKB:Q62717 synaptic transmission, glutamatergic ; GO:0035249 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | non-traceable author statement synaptic vesicle exocytosis ; GO:0016079 | inferred from sequence or structural similarity" synaptic vesicle ; GO:0008021 | non-traceable author statement synapse ; GO:0045202 | inferred from direct assay "dcaps, CG18026, dCAPS, l(4)102Fb, CG17881, CAPS, SDCAP, CG40477, CG33653, BcDNA:GH07283, Cadps, Caps, cap, caps" "IPR001849:Pleckstrin homology domain, IPR010439:Calcium-dependent secretion activator domain, IPR011993:PH domain-like, IPR014770:Munc13 homology 1, IPR033227:Calcium-dependent secretion activator" CG33653 27-Aug-18 DroID_v2018_08 "Drer\cadpsb, Drer\cadpsa, Drer\cadps2" - Cele\unc-31 "Xtro\cadps, Xtro\cadps2" "Mmus\Cadps2, Mmus\Unc13b, Mmus\Cadps, Mmus\Unc13a" "Hsap\UNC13A, Hsap\CADPS2, Hsap\CADPS" "viable,touch sensitivity defective,recessive,lethal,hypoactive,neurophysiology defective,locomotor behavior defective" "neuromuscular junction,synaptic vesicle" FBgn0003591 Su(var)2-9 Suppressor of variegation 2-9 http://flybase.org/reports/FBgn0003591 - gene - - - "Su-var(2)9, Su(var)2-9" - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive,suppressor of variegation,dominant" FBgn0283467 Pol32 Pol32 polymerase delta subunit http://flybase.org/reports/FBgn0283467 protein_coding_gene DNA polymerase binding ; GO:0070182 | inferred from sequence model DNA repair ; GO:0006281 | inferred from mutant phenotype DNA synthesis involved in double-strand break repair via homologous recombination ; GO:0043150 | inferred from mutant phenotype - "pol32, CG3975, rd, BG:DS07295.3, BcDNA:GH08865, Pol32" - CG3975 27-Aug-18 DroID_v2018_08 Drer\pold3 - Cele\R04F11.3 - Mmus\Pold3 Hsap\POLD3 FBgn0023053 l(1)3Aj lethal (1) 3Aj http://flybase.org/reports/FBgn0023053 - gene - - - "A2/3, l(1)3Aj" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0051245 CG31245 - http://flybase.org/reports/FBgn0051245 protein_coding_gene - - - "CG3575, BcDNA:AT17586, CG31245" IPR006623:Testicular haploid expressed repeat CG31245 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0019781 l(1)27 lethal (1) 27 http://flybase.org/reports/FBgn0019781 - gene - - - l(1)27 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0033844 bbc bb in a boxcar http://flybase.org/reports/FBgn0033844 protein_coding_gene "phosphotransferase activity, for other substituted phosphate groups ; GO:0016780 | inferred from electronic annotation with InterPro:IPR000462" phospholipid biosynthetic process ; GO:0008654 | inferred from electronic annotation with InterPro:IPR000462 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR000462 "Bbc, bbc, cept, CG6016, dCCS2" "IPR000462:CDP-alcohol phosphatidyltransferase, IPR014472:Choline/ethanolamine phosphotransferase" CG6016 27-Aug-18 DroID_v2018_08 "Drer\cept1a, Drer\cept1b, Drer\chpt1, Drer\si:ch211-197l9.4" "Scer\CPT1, Scer\EPT1" "Cele\cept-1, Cele\cept-2, Cele\F54D7.2" "Xtro\chpt1, Xtro\cept1, Xtro\ept1" "Mmus\Selenoi, Mmus\Chpt1, Mmus\Cept1" "Hsap\SELENOI, Hsap\CEPT1, Hsap\CHPT1" viable adult heart FBgn0028287 l(1)G0406 lethal (1) G0406 http://flybase.org/reports/FBgn0028287 gene - - - l(1)G0406 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0025339 anon-58Fd anon-58Fd http://flybase.org/reports/FBgn0025339 - gene - - - "B2.1, anon-58Fd" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037648 CG11975 - http://flybase.org/reports/FBgn0037648 protein_coding_gene - - - CG11975 "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG11975 27-Aug-18 DroID_v2018_08 "Drer\wipi2, Drer\wdr45, Drer\wdr45b" "Scer\ATG18, Scer\HSV2" "Cele\atg-18, Cele\epg-6" "Xtro\wdr45, Xtro\wdr45b" "Mmus\Wipi1, Mmus\Wdr45b, Mmus\Wdr45, Mmus\Wipi2" "Hsap\WDR45, Hsap\WDR45B, Hsap\WIPI2, Hsap\WIPI1" "viable,fertile" FBgn0044034 Mod(rst)E188 Mod(rst)E188 http://flybase.org/reports/FBgn0044034 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "E188, Mod(rst)E188" - - 27-Aug-18 DroID_v2018_08 - - - - - - viable "secondary pigment cell,ectopic,tertiary pigment cell" FBgn0028541 TM9SF4 Transmembrane 9 superfamily protein member 4 http://flybase.org/reports/FBgn0028541 protein_coding_gene transporter activity ; GO:0005215 | inferred from sequence or structural similarity phagocytosis ; GO:0006909 | inferred from mutant phenotype encapsulation of foreign target ; GO:0035010 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype negative regulation of peptidoglycan recognition protein signaling pathway ; GO:0061060 | inferred from mutant phenotype protein localization to plasma membrane ; GO:0072659 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000080197 "n(2)k07245, BG:DS00797.1, CG16861, TM9SF4, CG7364" IPR004240:Nonaspanin (TM9SF) CG7364 27-Aug-18 DroID_v2018_08 "Drer\top3a, Drer\tm9sf2, Drer\tm9sf4, Drer\LOC558202" "Scer\TMN3, Scer\EMP70, Scer\TMN2" "Cele\tag-123, Cele\top-3, Cele\ZK858.6" "Xtro\LOC100489507, Xtro\tm9sf2, Xtro\top3a" "Mmus\Tm9sf2, Mmus\Top3a, Mmus\Tm9sf4, Mmus\Gm364" "Hsap\TM9SF4, Hsap\TOP3A, Hsap\TM9SF2" "viable,fertile,immune response defective,partially lethal - majority live,wild-type,lethal - all die before end of pupal stage,some die during pupal stage" "plasmatocyte,sessile hemocyte,actin cytoskeleton & plasmatocyte" FBgn0050172 CG30172 - http://flybase.org/reports/FBgn0050172 protein_coding_gene - - extracellular region ; GO:0005576 | inferred from sequence model "anon-AE003462.1, BcDNA:RH70879, CG30172, DmelCSP1" IPR005055:Insect odorant-binding protein A10/Ejaculatory bulb-specific protein 3 CG30172 27-Aug-18 DroID_v2018_08 Drer\ifit15 - - - - - viable DRSC30069 K 0.112266434 0.467004458 0.457108159 -0.03190613 0.571615307 1.678506683 FBgn0011277 HLH4C Helix loop helix protein 4C http://flybase.org/reports/FBgn0011277 - protein_coding_gene "protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN001015390 RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from biological aspect of ancestor with PANTHER:PTN001015390" regulation of cell cycle ; GO:0051726 | inferred from direct assay nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001015390 "DroNHLH, EG:84H4.2, CG3052, HLH4C, bHLH36" "IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG3052 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-246m6.4, Drer\tcf15, Drer\tal1, Drer\nhlh2, Drer\tcf23, Drer\msc, Drer\tal2, Drer\ascl1b, Drer\tcf24, Drer\hand2, Drer\ascl1a, Drer\mespaa, Drer\scxa, Drer\mespab, Drer\ptf1a, Drer\atoh1c, Drer\figla, Drer\msgn1, Drer\tcf21, Drer\mespba, Drer\lyl1, Drer\scxb" - "Cele\hlh-15, Cele\hlh-3, Cele\hlh-13, Cele\hlh-12, Cele\lin-32" "Xtro\tal1, Xtro\ascl3, Xtro\hand2, Xtro\mespb, Xtro\ascl2, Xtro\figla, Xtro\msc, Xtro\scx, Xtro\nhlh1, Xtro\mespa, Xtro\ptf1a, Xtro\tcf21, Xtro\msgn1, Xtro\hand1, Xtro\lyl1, Xtro\tcf15" "Mmus\Msc, Mmus\Ascl3, Mmus\Tal1, Mmus\Hand2, Mmus\Tal2, Mmus\Mesp2, Mmus\Mesp1, Mmus\Msgn1, Mmus\Tcf15, Mmus\Ptf1a, Mmus\Ferd3l, Mmus\Nhlh1, Mmus\Hand1, Mmus\Ascl1, Mmus\Tcf21, Mmus\Lyl1, Mmus\Figla, Mmus\Ascl5, Mmus\Nhlh2, Mmus\Ascl4, Mmus\Scx, Mmus\Tcf23" "Hsap\MSGN1, Hsap\ASCL1, Hsap\NHLH2, Hsap\NHLH1, Hsap\ASCL5, Hsap\TAL2, Hsap\TAL1, Hsap\MESP2, Hsap\HAND1, Hsap\TCF15, Hsap\TCF21, Hsap\ASCL4, Hsap\MESP1, Hsap\TCF24, Hsap\ASCL3, Hsap\LYL1, Hsap\FIGLA, Hsap\TCF23, Hsap\SCX, Hsap\PTF1A, Hsap\MSC, Hsap\HAND2" " embryonic stage | stage >=12 , embryonic stage " " embryonic central nervous system | restricted

, neuron

" viable DRSC18670 I -1.56652381 0.309846124 0.08543051 0.579377511 0.262325871 0.52791879 FBgn0038132 CG15887 - http://flybase.org/reports/FBgn0038132 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE53127, CG15887" - CG15887 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0001807 l(1)Mc52 lethal (1) Mc52 http://flybase.org/reports/FBgn0001807 - gene - - - l(1)Mc52 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0041122 l(2)45Be lethal (2) 45Be http://flybase.org/reports/FBgn0041122 gene - - - l(2)45Be - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0265929 lncRNA:CR44718 - http://flybase.org/reports/FBgn0265929 non_protein_coding_gene - - - CR44718 - CR44718 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0041157 en::ovo en::ovo http://flybase.org/reports/FBgn0041157 engineered_fusion_gene - - - en::ovo - - 27-Aug-18 DroID_v2018_08 - - - - - - "egg chamber,embryonic/first instar larval cuticle,denticle belt" FBgn0005100 fs(3)350-7 female sterile (3) 350-7 http://flybase.org/reports/FBgn0005100 - gene - - - fs(3)350-7 - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive" "dorsal appendage,endochorion" FBgn0266893 lncRNA:CR45353 - http://flybase.org/reports/FBgn0266893 non_protein_coding_gene - - - CR45353 - CR45353 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259667 B0748 - http://flybase.org/reports/FBgn0259667 gene - - - B0748 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible wing vein L3 FBgn0265963 lncRNA:CR44750 - http://flybase.org/reports/FBgn0265963 non_protein_coding_gene - - - CR44750 - CR44750 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035138 CG13884 - http://flybase.org/reports/FBgn0035138 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT18596, CG13884" - CG13884 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" FBgn0267198 lncRNA:CR45638 - http://flybase.org/reports/FBgn0267198 non_protein_coding_gene - - - CR45638 - CR45638 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001870 l(1)XD03 lethal (1) XD03 http://flybase.org/reports/FBgn0001870 - gene - - - l(1)XD03 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005336 podM podoptera in M(3)w 124 http://flybase.org/reports/FBgn0005336 - gene - - - "pod-M, podM" - - 27-Aug-18 DroID_v2018_08 - - - - - - visible wing FBgn0033206 DCTN4-p62 "Dynactin 4, p62 subunit" http://flybase.org/reports/FBgn0033206 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype nuclear migration ; GO:0007097 | inferred from biological aspect of ancestor with PANTHER:PTN000989859 microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity dynactin complex ; GO:0005869 | inferred from biological aspect of ancestor with PANTHER:PTN000989859 cytoplasmic dynein complex ; GO:0005868 | inferred from biological aspect of ancestor with PANTHER:PTN000989859 dynactin complex ; GO:0005869 | inferred from sequence or structural similarity "CG12042, p62, DCTN4, DCTN4-p62, P62" IPR008603:Dynactin subunit 4 CG12042 27-Aug-18 DroID_v2018_08 Drer\dctn4 - Cele\dnc-4 Xtro\dctn4 Mmus\Dctn4 Hsap\DCTN4 "lethal,neuroanatomy defective,partially lethal - majority die,visible" "ganglion mother cell,mesothoracic tergum" FBgn0034094 Tsf3 Transferrin 3 http://flybase.org/reports/FBgn0034094 protein_coding_gene - - extracellular space ; GO:0005615 | inferred from electronic annotation with InterPro:IPR016357 "CG3666, Tsf3, tsf3" "IPR001156:Transferrin-like domain, IPR016357:Transferrin" CG3666 27-Aug-18 DroID_v2018_08 "Drer\otomp, Drer\mfi2, Drer\tfa, Drer\zgc:172271" - - "Xtro\tf, Xtro\mfi2, Xtro\depdc5" "Mmus\Trf, Mmus\Mfi2, Mmus\1300017J02Rik, Mmus\Ltf" "Hsap\TF, Hsap\LTF, Hsap\MELTF" "viable,locomotor rhythm defective" FBgn0032603 CG17928 - http://flybase.org/reports/FBgn0032603 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR012171 "lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR005804, InterPro:IPR012171 lateral inhibition ; GO:0046331 | inferred from mutant phenotype" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR012171 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN001047707 "anon-WO0118547.16, CG17928" "IPR001199:Cytochrome b5-like heme/steroid binding domain, IPR005804:Fatty acid desaturase domain, IPR012171:Fatty acid desaturase" CG17928 27-Aug-18 DroID_v2018_08 "Drer\dpm3, Drer\fads2" - "Cele\fbxa-76, Cele\C24H12.1, Cele\fat-3, Cele\T27A1.3, Cele\fat-4, Cele\F49E11.8" "Xtro\dpm3, Xtro\fads2" "Mmus\4833423E24Rik, Mmus\Fads3, Mmus\Fads1, Mmus\Dpm3, Mmus\Fads2" "Hsap\FADS3, Hsap\FADS2, Hsap\FADS1, Hsap\DPM3" "viable,visible" "chaeta,supernumerary" FBgn0060518 l(3)S103414 lethal (3) S103414 http://flybase.org/reports/FBgn0060518 gene - - - "1034/14, l(3)S103414" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0262887 lncRNA:CR43242 - http://flybase.org/reports/FBgn0262887 non_protein_coding_gene - - - CR43242 - CR43242 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032124 CG17855 - http://flybase.org/reports/FBgn0032124 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG17855 - CG17855 27-Aug-18 DroID_v2018_08 - Scer\RUD3 - Xtro\cttnbp2nl - Hsap\CTTNBP2NL viable FBgn0017545 RpS3A Ribosomal protein S3A http://flybase.org/reports/FBgn0017545 "FBgn0002630, FBgn0013757" protein_coding_gene "structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR001593, InterPro:IPR018281, InterPro:IPR027500 structural constituent of ribosome ; GO:0003735 | traceable author statement" "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR001593, InterPro:IPR018281, InterPro:IPR027500 cytoplasmic translation ; GO:0002181 | traceable author statement" "ribosome ; GO:0005840 | inferred from electronic annotation with InterPro:IPR001593, InterPro:IPR018281, InterPro:IPR027500 cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement" "CG2168, RPS3A, M(4)101, RpS3a, RPS3a, clone 2.29, M57g, C3, M[57g], M(4)57g, M(4)[57g], l(4)102ABa, anon-EST:Liang-2.29, RpS3A, chr4:86830..87021, chr4:87101..87234, chr4:87503..87595, Rps3A, Rsp3A" "IPR018281:Ribosomal protein S3Ae, conserved site, IPR001593:Ribosomal protein S3Ae, IPR027500:40S ribosomal protein S1/3, eukaryotes" CG2168 27-Aug-18 DroID_v2018_08 Drer\rps3a "Scer\RPS1B, Scer\RPS1A" Cele\rps-1 Xtro\rps3a Mmus\Rps3a1 Hsap\RPS3A " embryonic stage | stage 1-11 , adult stage | male , embryonic stage&&larval stage , adult stage | female "

ubiquitous "developmental rate defective,dominant,visible,Minute,size defective,lethal - all die before end of larval stage,recessive,some die during larval stage,female sterile,heat sensitive,lethal" "macrochaeta,adult heart,adult,egg chamber,heat sensitive,nurse cell,follicle cell" DRSC17168 EK -1.086216543 -0.589509061 1.878426332 -2.574878617 0.835754937 3.25600388 FBgn0264427 CG43845 - http://flybase.org/reports/FBgn0264427 protein_coding_gene - - - "CR43845, CG43845" - CG43845 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038727 CG7432 - http://flybase.org/reports/FBgn0038727 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP19, c-SP19, CG7432" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR022700:Proteinase, regulatory CLIP domain, IPR033116:Serine proteases, trypsin family, serine active site" CG7432 27-Aug-18 DroID_v2018_08 "Drer\ela2, Drer\zgc:92745, Drer\si:dkey-57c15.4, Drer\ela3l, Drer\zgc:92511, Drer\zgc:112302, Drer\zgc:112285, Drer\ctrl, Drer\ctrb1, Drer\ela2l, Drer\LOC562139, Drer\zgc:171592, Drer\si:dkey-238d18.3, Drer\zgc:92041, Drer\zgc:112368, Drer\zgc:112160, Drer\zgc:154142" - "Cele\try-1, Cele\try-3, Cele\clec-4, Cele\svh-1" "Xtro\mst1, Xtro\cela2a, Xtro\cela3a, Xtro\LOC100135144, Xtro\ctrb2, Xtro\ctrb1" "Mmus\Cela3b, Mmus\Cela3a, Mmus\Cela2a, Mmus\Prss30, Mmus\Cela1, Mmus\Plg, Mmus\Tmprss15, Mmus\Ctrb1, Mmus\Ctrl, Mmus\Hgf, Mmus\Mst1, Mmus\Ctrc, Mmus\F2" "Hsap\CELA3B, Hsap\CTRB2, Hsap\MST1, Hsap\MST1L, Hsap\HGF, Hsap\CELA3A, Hsap\CTRC, Hsap\F2, Hsap\CELA2B, Hsap\CELA2A, Hsap\TMPRSS15, Hsap\PLAT, Hsap\CTRB1, Hsap\CELA1, Hsap\PLG, Hsap\CTRL" viable FBgn0085596 CG41280 - http://flybase.org/reports/FBgn0085596 protein_coding_gene - - - CG41280 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0014080 anon-15Aa anon-15Aa http://flybase.org/reports/FBgn0014080 - gene - - - "gene x, anon-15Aa" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263986 cd cardinal http://flybase.org/reports/FBgn0263986 protein_coding_gene heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR010255 peroxidase activity ; GO:0004601 | inferred from biological aspect of ancestor with PANTHER:PTN000158755 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR010255 response to oxidative stress ; GO:0006979 | inferred from electronic annotation with InterPro:IPR010255 kynurenine metabolic process ; GO:0070189 | inferred from mutant phenotype negative regulation of gene silencing by RNA ; GO:0060967 | inferred from mutant phenotype ommochrome biosynthetic process ; GO:0006727 | inferred from mutant phenotype positive regulation of neuron death ; GO:1901216 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000895746 lysosome ; GO:0005764 | inferred from direct assay "cd, CG6969" "IPR010255:Haem peroxidase, IPR019791:Haem peroxidase, animal" CG6969 27-Aug-18 DroID_v2018_08 "Drer\epx, Drer\mpx, Drer\tpo, Drer\ptgs2b, Drer\pxdn, Drer\ptgs2a, Drer\ptgs1, Drer\igsf9bb" - "Cele\T06D8.10, Cele\skpo-3, Cele\pxn-2, Cele\skpo-2, Cele\K10B4.1, Cele\R08F11.7, Cele\C46A5.4, Cele\mlt-7, Cele\F09F3.5, Cele\pxn-1, Cele\skpo-1" "Xtro\epx, Xtro\ptgs1, Xtro\tpo, Xtro\pxdn, Xtro\mpo, Xtro\ptgs2" "Mmus\Pxdn, Mmus\Ptgs2, Mmus\Lpo, Mmus\Mpo, Mmus\Ptgs1, Mmus\Tpo, Mmus\Epx" "Hsap\PXDNL, Hsap\LPO, Hsap\PTGS2, Hsap\TPO, Hsap\EPX, Hsap\PXDN, Hsap\MPO, Hsap\PTGS1" FBgn0000259 CkIIbeta Casein kinase II beta subunit http://flybase.org/reports/FBgn0000259 FBgn0027953 protein_coding_gene protein kinase activity ; GO:0004672 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay protein kinase regulator activity ; GO:0019887 | inferred from direct assay eclosion rhythm ; GO:0008062 | traceable author statement protein phosphorylation ; GO:0006468 | non-traceable author statement cellular response to starvation ; GO:0009267 | inferred from expression pattern neurogenesis ; GO:0022008 | inferred from mutant phenotype rhythmic behavior ; GO:0007622 | traceable author statement circadian rhythm ; GO:0007623 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype intracellular mRNA localization involved in pattern specification process ; GO:0060810 | inferred from genetic interaction with CkIIα locomotor rhythm ; GO:0045475 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from direct assay oocyte dorsal/ventral axis specification ; GO:0007310 | inferred from mutant phenotype inferred from genetic interaction with orb cytoplasm ; GO:0005737 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay protein kinase CK2 complex ; GO:0005956 | inferred from direct assay "CK2, CKII, CkII-beta, CK2beta, DmCKIIbeta, dCKII, DmCK2beta, CKIIbeta, CkIIbeta1, betaCK2, DmCkIIbeta, CKIIb, CG15224, CK II, CKII-beta1, mbu, CkII, And, CCK2, CK-IIbeta, CK-II beta, CK-2, Ds cas kin, CkIIbeta, Cask-II-b, CKII beta, dCK2beta, dCKII beta, Ckiibeta, CK2-beta, Ck-IIbeta, KC2B_DROME, ck2beta, Ck2beta, Dm-CK2-beta" "IPR000704:Casein kinase II, regulatory subunit, IPR016149:Casein kinase II, regulatory subunit, alpha-helical" CG15224 27-Aug-18 DroID_v2018_08 Drer\csnk2b "Scer\CKB2, Scer\CKB1" Cele\kin-10 Xtro\csnk2b Mmus\Csnk2b "Hsap\CSNK2B, Hsap\LY6G5B" "circadian rhythm defective,viable,female sterile,partially,male sterile,neuroanatomy defective,visible,lethal,recessive,behavior defective,semidominant,eclosion rhythm defective,locomotor rhythm defective,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die during pupal stage,circadian behavior defective" "Kenyon cell,calyx of adult mushroom body,adult mushroom body,synapse,neuromuscular junction,wing vein,peripheral nervous system,longitudinal connective,ventral nerve cord commissure,synapse | somatic clone,neuromuscular junction | somatic clone,chorion | maternal effect,embryonic/larval neuroblast,ganglion mother cell" FBgn0033074 tomboy40 tomboy40 http://flybase.org/reports/FBgn0033074 protein_coding_gene P-P-bond-hydrolysis-driven protein transmembrane transporter activity ; GO:0015450 | inferred from sequence or structural similarity with UniProtKB:O96008 protein channel activity ; GO:0015266 | inferred from biological aspect of ancestor with PANTHER:PTN000085854 protein targeting to mitochondrion ; GO:0006626 | inferred from sequence or structural similarity with UniProtKB:O96008 protein import into mitochondrial matrix ; GO:0030150 | inferred from biological aspect of ancestor with PANTHER:PTN000085854 protein targeting to mitochondrion ; GO:0006626 | inferred from sequence or structural similarity with UniProtKB:Q75Q40 mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial intermembrane space protein transporter complex ; GO:0042719 | inferred from direct assay mitochondrial outer membrane translocase complex ; GO:0005742 | inferred from biological aspect of ancestor with PANTHER:PTN000085854 mitochondrial outer membrane translocase complex ; GO:0005742 | inferred from sequence or structural similarity with UniProtKB:O96008 "CG8330, tomboy40, Tomboy40" IPR027246:Eukaryotic porin/Tom40 CG8330 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-71l1.1, Drer\tomm40l, Drer\tomm40" Scer\TOM40 Cele\tomm-40 "Xtro\tomm40l, Xtro\tomm40" "Mmus\Tomm40, Mmus\Tomm40l" "Hsap\TOMM40L, Hsap\TOMM40" "viable,visible,lethal" trichogen cell FBgn0020313 anon-9C1 anon-9C1 http://flybase.org/reports/FBgn0020313 - gene - - - "9C1, anon-9C1" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0044394 Scim34 Sensitized chromosome inheritance modifier 34 http://flybase.org/reports/FBgn0044394 gene - female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype - Scim34 - - 27-Aug-18 DroID_v2018_08 - - - - - - "meiotic cell cycle defective,dominant" FBgn0044093 E(rst)D187 E(rst)D187 http://flybase.org/reports/FBgn0044093 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "D187, E(rst)D187" - - 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0013278 Hsp70Bb Heat-shock-protein-70Bb http://flybase.org/reports/FBgn0013278 "FBgn0001232, FBgn0051359" protein_coding_gene - response to heat ; GO:0009408 | inferred from mutant phenotype response to hypoxia ; GO:0001666 | inferred from expression pattern inferred from mutant phenotype heat shock-mediated polytene chromosome puffing ; GO:0035080 | inferred from mutant phenotype response to heat ; GO:0009408 | non-traceable author statement response to unfolded protein ; GO:0006986 | non-traceable author statement microtubule associated complex ; GO:0005875 | inferred from direct assay "Hsp70, hsp70, HSP70, hsp70Bb, hsp70B, Hsp70Bc, Hsp70B, Hsp70Bbc, DMHSP7D1, Hsp 70, Hsp70A7d, dhsp70, Hsp70(87C), hsp-70, hsp70 87C, CG31359, Hsp70Bb, Hsp-70, dHsp70, Dm-hsp70, Bb, Hsp70bb" "IPR018181:Heat shock protein 70, conserved site, IPR013126:Heat shock protein 70 family, IPR029048:Heat shock protein 70kD, C-terminal domain, IPR029047:Heat shock protein 70kD, peptide-binding domain" CG31359 27-Aug-18 DroID_v2018_08 "Drer\hsp70l, Drer\hspa8, Drer\hsp70.1, Drer\si:ch211-199o1.2, Drer\nckap1, Drer\hspa12b, Drer\hspa5, Drer\hspa13, Drer\hspa12a, Drer\hsp70.2, Drer\si:dkey-4p15.3, Drer\hsc70, Drer\hspa14" "Scer\SSQ1, Scer\SSB1, Scer\SSZ1, Scer\ECM10, Scer\SSA3, Scer\SSB2, Scer\SSA2, Scer\SSA1, Scer\KAR2, Scer\SSA4" "Cele\gex-3, Cele\hsp-3, Cele\F44E5.5, Cele\F44E5.4, Cele\F11F1.1, Cele\hsp-4, Cele\hsp-1, Cele\hsp-70" "Xtro\hspa14, Xtro\hspa1a, Xtro\hspa8, Xtro\hspa12b, Xtro\hspa13, Xtro\hspa2, Xtro\nckap1, Xtro\hspa1l, Xtro\nckap1l, Xtro\hspa1b, Xtro\hsp70, Xtro\hspa5" "Mmus\Hspa1l, Mmus\Hspa12a, Mmus\Hspa2, Mmus\Hspa8, Mmus\Hspa12b, Mmus\Hspa5, Mmus\Hspa1a, Mmus\Hspa14, Mmus\Hspa13, Mmus\Nckap1, Mmus\Nckap1l, Mmus\Hspa1b" "Hsap\HSPA12A, Hsap\HSPA1B, Hsap\HSPA1A, Hsap\HSPA12B, Hsap\HSPA1L, Hsap\HSPA2, Hsap\NCKAP1, Hsap\HSPA13, Hsap\HSPA5, Hsap\HSPA6, Hsap\NCKAP1L, Hsap\HSPA8, Hsap\HSPA14" "aging defective,male limited,heat sensitive" FBgn0034288 CG5084 - http://flybase.org/reports/FBgn0034288 protein_coding_gene - - - CG5084 IPR007931:Protein of unknown function DUF725 CG5084 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0016935 smi65A smell impaired 65A http://flybase.org/reports/FBgn0016935 - gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - smi65A - - 27-Aug-18 DroID_v2018_08 - - - - - - "smell perception defective,behavior defective,recessive" FBgn0015495 l(3)65ACe lethal (3) 65ACe http://flybase.org/reports/FBgn0015495 - gene - - - "V, l(3)65ACe" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0020768 1731\gag 1731 element gag http://flybase.org/reports/FBgn0020768 - transposable_element_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001878 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001878 - - "ORF1, 1731\gag" "IPR001878:Zinc finger, CCHC-type" - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0041763 btd::Hsap\SP1 btd::Hsap\SP1 http://flybase.org/reports/FBgn0041763 engineered_fusion_gene - - - btd::Hsap\SP1 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0015494 l(3)65ACd lethal (3) 65ACd http://flybase.org/reports/FBgn0015494 - gene - - - "IV, l(3)65ACd" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0267571 lncRNA:CR45911 - http://flybase.org/reports/FBgn0267571 non_protein_coding_gene - - - "CR45911, pri-mir-13b-1_mir-13a_mir-2c" - CR45911 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0052650 CG32650 - http://flybase.org/reports/FBgn0052650 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG4410, CG32650" IPR031883:Protein of unknown function DUF4763 CG32650 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-36g24.3, Drer\adck3, Drer\adck4" Scer\COQ8 - "Xtro\adck3, Xtro\adck4" "Mmus\Coq8b, Mmus\Coq8a" "Hsap\COQ8B, Hsap\COQ8A" viable FBgn0266216 asRNA:CR44911 - http://flybase.org/reports/FBgn0266216 non_protein_coding_gene - - - CR44911 - CR44911 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0016046 noah noah http://flybase.org/reports/FBgn0016046 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available noah - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0028305 l(1)G0377 lethal (1) G0377 http://flybase.org/reports/FBgn0028305 gene - - - l(1)G0377 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" brain FBgn0067754 l(1)G0096 lethal (1) G0096 http://flybase.org/reports/FBgn0067754 gene - - - l(1)G0096 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0259404 C427 - http://flybase.org/reports/FBgn0259404 gene - - - C427 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing vein,wing hair,wing,chaeta" FBgn0069246 bum boojum http://flybase.org/reports/FBgn0069246 gene molecular_function ; GO:0003674 | no biological data available axonogenesis ; GO:0007409 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available bum - - 27-Aug-18 DroID_v2018_08 - - - - - - neuroanatomy defective "dendritic arborizing neuron,axon,dendrite,commissure" FBgn0035253 CG7971 - http://flybase.org/reports/FBgn0035253 protein_coding_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 RNA splicing ; GO:0008380 | inferred from sequence or structural similarity with protein_id:AAF21439" precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "anon-EST:fe1A7, BcDNA:GH04236, CG7971" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR029360:Serine/arginine repetitive matrix protein, C-terminal, IPR013170:mRNA splicing factor Cwf21 domain" CG7971 27-Aug-18 DroID_v2018_08 Drer\srrm2 Scer\CWC21 Cele\rsr-2 "Xtro\srrm2, Xtro\nktr" "Mmus\Srrm2, Mmus\Dspp, Mmus\Srrm3" "Hsap\DSPP, Hsap\SRRM3, Hsap\SRRM2" FBgn0051759 CG31759 - http://flybase.org/reports/FBgn0051759 protein_coding_gene - - - "BcDNA:AT13596, ms(2)01284, BcDNA:LD05405, CG31759, 3635, d3635" IPR005135:Endonuclease/exonuclease/phosphatase CG31759 27-Aug-18 DroID_v2018_08 "Drer\pde12, Drer\cnot6a, Drer\cnot6b, Drer\cnot6l, Drer\nocta" "Scer\CCR4, Scer\NGL3, Scer\NGL1, Scer\NGL2" Cele\pde-12 "Xtro\noct, Xtro\cnot6l" "Mmus\Cnot6l, Mmus\Lrrc27, Mmus\Cnot6, Mmus\Noct, Mmus\Angel2, Mmus\Pde12" "Hsap\PDE12, Hsap\CNOT6, Hsap\CNOT6L, Hsap\NOCT, Hsap\ANGEL2" "male sterile,recessive,partially lethal - majority die,viable" FBgn0267926 lncRNA:CR46207 - http://flybase.org/reports/FBgn0267926 non_protein_coding_gene - - - "CR46207, lincRNA.912" - CR46207 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0024668 l(2)k04207 lethal (2) k04207 http://flybase.org/reports/FBgn0024668 - gene - - - "42/7, l(2)k04207" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0014978 l(2)23Ab lethal (2) 23Ab http://flybase.org/reports/FBgn0014978 - gene molecular_function ; GO:0003674 | no biological data available nervous system development ; GO:0007399 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available l(2)23Ab - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,lethal - all die before end of larval stage,some die during larval stage" "peripheral nervous system,central nervous system,peripheral nervous system precursor cluster" FBgn0032266 CG18302 - http://flybase.org/reports/FBgn0032266 protein_coding_gene "hydrolase activity, acting on ester bonds ; GO:0016788 | inferred from electronic annotation with InterPro:IPR025483" lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR006693 - CG18302 "IPR025483:Lipase, eukaryotic, IPR006693:Partial AB-hydrolase lipase domain, IPR029058:Alpha/Beta hydrolase fold" CG18302 27-Aug-18 DroID_v2018_08 Drer\lipf "Scer\YEH2, Scer\TGL1, Scer\YEH1" "Cele\lipl-7, Cele\lipl-6, Cele\lipl-8, Cele\lipl-3, Cele\lipl-4, Cele\lipl-1, Cele\lipl-2, Cele\lipl-5" Xtro\lipa "Mmus\Lipo3, Mmus\Lipo2, Mmus\Lipf, Mmus\Lipo1, Mmus\Lipa, Mmus\Lipk, Mmus\Lipo4, Mmus\Lipn, Mmus\Lipm" "Hsap\LIPN, Hsap\LIPJ, Hsap\LIPM, Hsap\LIPF, Hsap\LIPK, Hsap\LIPA" viable FBgn0028250 l(3)91Ce lethal (3) 91Ce http://flybase.org/reports/FBgn0028250 gene - - - l(3)91Ce - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0065370 l(2)SH1702 lethal (2) SH1702 http://flybase.org/reports/FBgn0065370 gene - - - "l(2)SH1702, l(2)SH2 1702" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0264361 CG43813 - http://flybase.org/reports/FBgn0264361 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43813 - CG43813 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0045864 blood\ORF2 blood element ORF2 http://flybase.org/reports/FBgn0045864 transposable_element_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR012337 DNA integration ; GO:0015074 | inferred from electronic annotation with InterPro:IPR001584 - blood\ORF2 "IPR026523:Paraneoplastic antigen Ma, IPR000477:Reverse transcriptase domain, IPR001584:Integrase, catalytic core, IPR015416:Zinc finger, H2C2-type, histone UAS binding, IPR012337:Ribonuclease H-like domain" - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0062639 EP924 EP924 http://flybase.org/reports/FBgn0062639 gene - - - "EP(3)0924, EP924" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263780 CG17684 - http://flybase.org/reports/FBgn0263780 protein_coding_gene serine-type peptidase activity ; GO:0008236 | inferred from electronic annotation with InterPro:IPR001375 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001375, InterPro:IPR002469" - "CG17684, CG40072, CG40260" "IPR001375:Peptidase S9, prolyl oligopeptidase, catalytic domain, IPR002469:Dipeptidylpeptidase IV, N-terminal domain, IPR029058:Alpha/Beta hydrolase fold" CG17684 27-Aug-18 DroID_v2018_08 "Drer\apeh, Drer\fap, Drer\zgc:136971, Drer\LOC101886435, Drer\dpp6a, Drer\LOC101883320, Drer\dpp4, Drer\dpp6b" "Scer\DAP2, Scer\STE13" "Cele\dpf-1, Cele\dpf-2" "Xtro\apeh, Xtro\dpp6, Xtro\dpp4, Xtro\dpp10" "Mmus\Apeh, Mmus\Fap, Mmus\Dpp6, Mmus\Dpp4, Mmus\Dpp10" "Hsap\DPP6, Hsap\FAP, Hsap\DPP10, Hsap\APEH, Hsap\DPP4" FBgn0030611 CG15027 - http://flybase.org/reports/FBgn0030611 protein_coding_gene - - nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001000592 ribosome ; GO:0005840 | colocalizes_with inferred from biological aspect of ancestor with PANTHER:PTN001000592 "BcDNA:SD22530, CG15027" IPR021346:Translation machinery-associated protein 16 CG15027 27-Aug-18 DroID_v2018_08 Drer\tma16 Scer\TMA16 - Xtro\tma16 Mmus\Tma16 Hsap\TMA16 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0047217 CR31456 - http://flybase.org/reports/FBgn0047217 non_protein_coding_gene - - - "BcDNA:LD10401, CR31456" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000395 cv-2 crossveinless 2 http://flybase.org/reports/FBgn0000395 FBgn0034625 protein_coding_gene BMP binding ; GO:0036122 | inferred from physical interaction with dpp inferred from physical interaction with gbb heparan sulfate proteoglycan binding ; GO:0043395 | inferred from genetic interaction with botv BMP receptor binding ; GO:0070700 | inferred from physical interaction with tkv endothelial cell differentiation ; GO:0045446 | inferred from electronic annotation with InterPro:IPR030120 negative regulation of BMP signaling pathway ; GO:0030514 | inferred from electronic annotation with InterPro:IPR030120 regulation of BMP signaling pathway ; GO:0030510 | inferred from genetic interaction with sog inferred from physical interaction with dpp inferred from physical interaction with tkv inferred from physical interaction with gbb imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype cell surface ; GO:0009986 | inferred from direct assay "Cv2, Cv 2, cv 2, CT35855, CG15671, cv-2, BMPER, Cv-2, CV2" "IPR001007:VWFC domain, IPR001846:von Willebrand factor, type D domain, IPR014853:Uncharacterised domain, cysteine-rich, IPR030120:BMP-binding endothelial regulator protein" CG15671 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-283b1.7, Drer\muc5d, Drer\si:dkey-266m15.6, Drer\LOC100332723, Drer\vwc2, Drer\bmper, Drer\zgc:113531, Drer\vwc2l" - Cele\T01D3.6 "Xtro\kcp, Xtro\vwc2, Xtro\bmper, Xtro\vwc2l.2" "Mmus\Vwc2, Mmus\Bmper, Mmus\Vwc2l, Mmus\Fcgbp, Mmus\Chrdl2, Mmus\Kcp" "Hsap\FCGBP, Hsap\BMPER, Hsap\VWC2L, Hsap\VWC2, Hsap\CHRDL2, Hsap\KCP" "viable,partially lethal - majority die,cold sensitive,visible,dominant,recessive,lethal" "wing,wing vein,posterior crossvein,anterior crossvein,ectopic,posterior,crossvein" FBgn0083996 CG41354 - http://flybase.org/reports/FBgn0083996 protein_coding_gene - - - CG41354 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0014304 l(3)neo14 lethal (3) neo14 http://flybase.org/reports/FBgn0014304 - gene - - - l(3)neo14 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0038422 CG14880 - http://flybase.org/reports/FBgn0038422 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG14880 IPR002557:Chitin binding domain CG14880 27-Aug-18 DroID_v2018_08 - - Cele\Y56A3A.6 - - - FBgn0262454 mir-1007 mir-1007 stem loop http://flybase.org/reports/FBgn0262454 miRNA_gene - - - "dme-mir-1007, mir-1007, MIR-1007, CR43025, miR-1007" - CR43025 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0084002 CG41435 - http://flybase.org/reports/FBgn0084002 protein_coding_gene - - - CG41435 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0011921 tRNA:iMet-CAT-2-1 transfer RNA:initiator Methionine-CAT 2-1 http://flybase.org/reports/FBgn0011921 "FBgn0050003, FBgn0050262, FBgn0060138" tRNA_gene AUG codon-amino acid adaptor activity ; GO:0033436 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033436 cytosol ; GO:0005829 | inferred by curator from GO:0033436 "AE002787.trna31-MetCAT, tRNA:M:CAT:AE002787-c, tRNA:met3:46A, CR30262, CR30003, tRNA:met:46A, tRNA[Met-ATG], chr2R.trna13-MetCAT, tRNA-iMet-CAT-2-1, tRNA:iMet-CAT-2-1, tRNA:M3:46A" - CR30003 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0020633 Mcm7 Minichromosome maintenance 7 http://flybase.org/reports/FBgn0020633 FBgn0025980 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001208, InterPro:IPR008050, InterPro:IPR018525 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001208, InterPro:IPR008050, InterPro:IPR018525 3'-5' DNA helicase activity ; GO:0043138 | contributes_to inferred from direct assay" DNA replication initiation ; GO:0006270 | inferred from electronic annotation with InterPro:IPR008050 mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR008050 MCM complex ; GO:0042555 | inferred from electronic annotation with InterPro:IPR008050 microtubule associated complex ; GO:0005875 | inferred from direct assay "MCM7, mcm7, CG4978, DmMCM7, PCR1, clone 1.66, anon-EST:Liang-1.66, Mcp-PCR1, Mcm7, McM7, DmeMCM7, dMcm7" "IPR018525:Mini-chromosome maintenance, conserved site, IPR001208:MCM domain, IPR003593:AAA+ ATPase domain, IPR008050:DNA replication licensing factor Mcm7, IPR012340:Nucleic acid-binding, OB-fold, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR033762:MCM OB domain, IPR027925:MCM N-terminal domain, IPR031327:Mini-chromosome maintenance protein" CG4978 27-Aug-18 DroID_v2018_08 Drer\mcm7 "Scer\MCM7, Scer\MCM4" Cele\mcm-7 Xtro\mcm7 Mmus\Mcm7 Hsap\MCM7 " embryonic stage | 0-4 hr , embryonic stage | stage 11-12 , egg stage | unfertilized egg , adult stage | female " " embryonic central nervous system

, unfertilized egg

" "viable,fertile,radiation sensitive" FBgn0028266 l(1)G0444 lethal (1) G0444 http://flybase.org/reports/FBgn0028266 gene - - - l(1)G0444 - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0060668 l(3)S080301 lethal (3) S080301 http://flybase.org/reports/FBgn0060668 gene - - - "0803/01, l(3)S080301" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0031739 CG14005 - http://flybase.org/reports/FBgn0031739 protein_coding_gene - - - CG14005 IPR026095:Myb/SANT-like DNA-binding domain-containing protein CG14005 27-Aug-18 DroID_v2018_08 Drer\msantd1 - - - Mmus\Msantd1 Hsap\MSANTD1 "viable,fertile" embryonic/larval salivary gland FBgn0058275 CG40275 - http://flybase.org/reports/FBgn0058275 protein_coding_gene - - - CG40275 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002072 l(2)49Fa lethal (2) 49Fa http://flybase.org/reports/FBgn0002072 - gene - - - "vr3, vr-3, l(2)vr3, l(2)6, l(2)49Fa" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,partially lethal - majority die,heat sensitive,non-suppressor of variegation,dominant" FBgn0085336 CG34307 - http://flybase.org/reports/FBgn0085336 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34307 - CG34307 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0015937 emu emu http://flybase.org/reports/FBgn0015937 - gene DNA binding ; GO:0003677 | inferred from sequence or structural similarity biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "bk36, emu" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267511 28SrRNA-Psi:CR45851 28S ribosomal RNA pseudogene:CR45851 http://flybase.org/reports/FBgn0267511 pseudogene_attribute - - - "28SrRNA-Psi:CR45851, CR45851" - CR45851 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0003070 Pfd Pufdi http://flybase.org/reports/FBgn0003070 - gene - - - Pfd - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" "wing,cold sensitive" FBgn0267603 lncRNA:CR45941 - http://flybase.org/reports/FBgn0267603 non_protein_coding_gene - - - CR45941 - CR45941 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037856 Leash Leash http://flybase.org/reports/FBgn0037856 protein_coding_gene - regulation of hippo signaling ; GO:0035330 | inferred from mutant phenotype cytoplasmic vesicle ; GO:0031410 | inferred from direct assay "CG32471, CG4674, leash, Leash" "IPR011021:Arrestin-like, N-terminal, IPR011022:Arrestin C-terminal-like domain, IPR014756:Immunoglobulin E-set" CG4674 27-Aug-18 DroID_v2018_08 "Drer\arrdc3b, Drer\arrdc3a, Drer\arrdc1a, Drer\txnipb, Drer\LOC799768, Drer\txnipa, Drer\arrdc2, Drer\si:ch211-130m23.2, Drer\zgc:110626, Drer\zgc:110353, Drer\arrdc1b" "Scer\ART5, Scer\ALY1, Scer\CSR2, Scer\RIM8, Scer\ALY2, Scer\ROG3, Scer\LDB19, Scer\ECM21, Scer\ROD1" "Cele\arrd-22, Cele\arrd-5, Cele\arrd-19, Cele\arrd-3, Cele\rnh-1.2, Cele\arrd-4, Cele\arrd-6, Cele\arrd-16, Cele\arrd-13, Cele\arrd-24, Cele\arrd-18, Cele\arrd-7, Cele\arrd-23, Cele\arrd-25, Cele\arrd-8, Cele\arrd-27, Cele\arrd-15, Cele\arrd-1, Cele\arrd-12, Cele\arrd-14, Cele\arrd-9, Cele\arrd-11, Cele\arrd-2" "Xtro\arrdc3, Xtro\txnip, Xtro\arrdc2, Xtro\arrdc4" "Mmus\Arrdc2, Mmus\Arrdc3, Mmus\Arrdc4, Mmus\Txnip, Mmus\Arrdc1, Mmus\Arrdc5" "Hsap\ARRDC3, Hsap\ARRDC1, Hsap\ARRDC4, Hsap\ARRDC5, Hsap\TXNIP, Hsap\ARRDC2" "viable,fertile,neuroanatomy defective,lethal - all die before end of larval stage,some die during larval stage,size defective" "neurite | pharate adult stage,wing" FBgn0027274 l(1)G0202 lethal (1) G0202 http://flybase.org/reports/FBgn0027274 - gene - - - l(1)G0202 - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive,female sterile" egg FBgn0038162 CG14368 - http://flybase.org/reports/FBgn0038162 protein_coding_gene - - - CG14368 - - 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC14830 K -0.838792933 1.29471163 0.301042628 0.123035314 1.724436304 0.751494515 FBgn0030782 CG18358 - http://flybase.org/reports/FBgn0030782 protein_coding_gene - - - "CG9644, BcDNA:RE13557, CG18358" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0250871 pot papillote http://flybase.org/reports/FBgn0250871 protein_coding_gene molecular_function ; GO:0003674 | no biological data available chitin-based cuticle attachment to epithelium ; GO:0040005 | inferred from mutant phenotype synaptic target recognition ; GO:0008039 | inferred from mutant phenotype apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | inferred from mutant phenotype chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | inferred from mutant phenotype apical part of cell ; GO:0045177 | inferred from direct assay "pot, CG2467" IPR001507:Zona pellucida domain CG2467 27-Aug-18 DroID_v2018_08 - - "Cele\cutl-12, Cele\cutl-20, Cele\cutl-6, Cele\cutl-13, Cele\cutl-1, Cele\cutl-16, Cele\cutl-28, Cele\cutl-11, Cele\cut-6, Cele\cutl-2, Cele\cutl-24, Cele\cutl-5, Cele\dpy-1, Cele\cutl-10, Cele\cutl-8, Cele\cutl-22, Cele\cutl-7, Cele\cutl-9, Cele\cutl-4, Cele\T01D1.8, Cele\cutl-29, Cele\cutl-19, Cele\cutl-14, Cele\cut-3, Cele\cutl-15, Cele\ram-5, Cele\F46G11.6, Cele\cut-4, Cele\cutl-3, Cele\cut-1, Cele\cutl-25, Cele\cut-5, Cele\cutl-26" - - - FBgn0267891 CR46179 - http://flybase.org/reports/FBgn0267891 pseudogene_attribute - - - "CR46179, CG12717-related" - CR46179 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0046642 anon-38D.3 anon-38D.3 http://flybase.org/reports/FBgn0046642 gene - - - "38D.3, anon-38D.3" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030590 CG9518 - http://flybase.org/reports/FBgn0030590 protein_coding_gene "oxidoreductase activity, acting on CH-OH group of donors ; GO:0016614 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR007867, InterPro:IPR012132 flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR012132 oxidoreductase activity ; GO:0016491 | inferred from sequence or structural similarity with Eo" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR007867, InterPro:IPR012132, InterPro:IPR023753 response to endoplasmic reticulum stress ; GO:0034976 | inferred from mutant phenotype ecdysteroid metabolic process ; GO:0045455 | inferred from sequence or structural similarity with Eo inferred from genomic context with Eo lateral inhibition ; GO:0046331 | inferred from mutant phenotype" - "CG9518, Dm GMCzeta1" "IPR000172:Glucose-methanol-choline oxidoreductase, N-terminal, IPR007867:Glucose-methanol-choline oxidoreductase, C-terminal, IPR012132:Glucose-methanol-choline oxidoreductase, IPR023753:FAD/NAD(P)-binding domain" CG9518 27-Aug-18 DroID_v2018_08 Drer\chdh - Cele\C34C6.4 - Mmus\Chdh Hsap\CHDH "viable,visible" "chaeta,supernumerary,trichogen cell" FBgn0039859 CG11539 - http://flybase.org/reports/FBgn0039859 protein_coding_gene N-acetyltransferase activity ; GO:0008080 | inferred from electronic annotation with InterPro:IPR000182 histone acetylation ; GO:0016573 | inferred from mutant phenotype - "NAT9, CG11539" "IPR000182:GNAT domain, IPR016181:Acyl-CoA N-acyltransferase" CG11539 27-Aug-18 DroID_v2018_08 Drer\nat9 - Cele\Y67D2.5 Xtro\nat9 Mmus\Nat9 Hsap\NAT9 "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0058176 CG40176 - http://flybase.org/reports/FBgn0058176 protein_coding_gene - - - CG40176 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0050029 CR30029 - http://flybase.org/reports/FBgn0050029 pseudogene_attribute - - - "CG30029, CG18337, BcDNA:LP05669, CR30029, CG34226" - CR30029 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,some die during pupal stage,viable" DRSC06724 I 1.870999871 -0.459854274 0.238191942 0.616532021 -1.102323571 -0.936770881 FBgn0004050 z zeste http://flybase.org/reports/FBgn0004050 "FBtr0070435, FBpp0070419" protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with mor inferred from physical interaction with p400 inferred from physical interaction with Bap170 sequence-specific DNA binding ; GO:0043565 | inferred from direct assay "positive regulation of gene expression ; GO:0010628 | inferred from mutant phenotype positive regulation of chromatin silencing ; GO:0031937 | inferred from direct assay ommochrome biosynthetic process ; GO:0006727 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from direct assay" nucleus ; GO:0005634 | inferred from direct assay intercalary heterochromatin ; GO:0005725 | non-traceable author statement PRC1 complex ; GO:0035102 | traceable author statement polytene chromosome interband ; GO:0005705 | inferred from direct assay "Z, CG7803, EG:BACH59J11.3, en-bx, e(bx), z" "IPR011989:Armadillo-like helical, IPR028002:Myb/SANT-like DNA-binding domain" CG7803 27-Aug-18 DroID_v2018_08 - - - - Mmus\Rb1 Hsap\RB1 " larval stage | late third instar larval stage--prepupal stage , embryonic stage | stage >=9 , larval stage | early third instar larval stage , adult stage , pharate adult stage , embryonic stage -- adult stage , pupal stage , larval stage | third instar stage 2--P " " ring gland

, organism

, embryonic/larval digestive system | restricted

, gonad

, adult muscle system | restricted

, larval central nervous system

, embryonic/larval salivary gland

, antenna

, adult abdomen

, imaginal disc

, Malpighian tubule

, adult brain

" "viable,visible,dominant,wild-type,eye color defective,recessive,lethal" "eye,pigment cell" FBgn0000605 E(var)c101 Enhancer of variegation c101 http://flybase.org/reports/FBgn0000605 - gene - - - "E-var(3)1, E(var)c[101], E(var)c101" - - 27-Aug-18 DroID_v2018_08 - - - - - - "enhancer of variegation,dominant,viable,female fertile,male fertile" FBgn0069158 mcl(3)Z2138 mcl(3)Z2138 http://flybase.org/reports/FBgn0069158 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z2138 - - 27-Aug-18 DroID_v2018_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0085468 ND-MWFE NADH dehydrogenase (ubiquinone) MWFE subunit http://flybase.org/reports/FBgn0085468 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with HGNC:7683 "CG13328, CG30057, CG17054, BcDNA:RH49308, l(2)c00093, CG34439, ND-MWFE" "IPR017384:NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex subunit 1" CG34439 27-Aug-18 DroID_v2018_08 "Drer\ndufa1, Drer\ncapg" - Cele\F31D4.9 Xtro\ncapg "Mmus\Ndufa1, Mmus\Ncapg" "Hsap\NDUFA1, Hsap\NCAPG" "lethal,recessive" FBgn0001737 l(1)HM7 lethal (1) HM7 http://flybase.org/reports/FBgn0001737 - gene - - - l(1)HM7 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,cold sensitive,female fertile" FBgn0053664 CG33664 - http://flybase.org/reports/FBgn0053664 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33664 - CG33664 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265485 BG00357 - http://flybase.org/reports/FBgn0265485 gene - - - BG00357 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040885 CG14189 - http://flybase.org/reports/FBgn0040885 protein_coding_gene - - - CG14189 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0027335 Rip11 Rab11 interacting protein http://flybase.org/reports/FBgn0027335 "FBgn0027272, FBgn0027314, FBgn0027318, FBgn0028271, FBgn0030942, FBgn0040180" protein_coding_gene Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab11 regulated exocytosis ; GO:0045055 | inferred from biological aspect of ancestor with PANTHER:PTN000405433 rhabdomere development ; GO:0042052 | inferred from mutant phenotype intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000405433 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000405433 "Rip11, l(1)G0297, CG6606, l(1)G0070, l(1)G0092, l(1)G0205, l(1)G0434, dRip11, l(1)G0003" "IPR000008:C2 domain, IPR019018:Rab-binding domain FIP-RBD" CG6606 27-Aug-18 DroID_v2018_08 "Drer\rab11fip1a, Drer\rab11fip1b, Drer\LOC570939, Drer\rab11fip5a, Drer\rab11fip2" - Cele\Y39F10B.1 "Xtro\rab11fip5, Xtro\rab11fip2, Xtro\rab11fip1" "Mmus\Rab11fip5, Mmus\Rab11fip1, Mmus\Rab11fip2" "Hsap\RAB11FIP2, Hsap\RAB11FIP5, Hsap\RAB11FIP1" "partially lethal - majority die,recessive,lethal,male,female,lethal - all die before end of P-stage,some die during pharate adult stage" "pupa,rhabdomere,somatic clone,actin cytoskeleton & eye photoreceptor cell | somatic clone,eye photoreceptor cell,rhabdomere | ectopic | somatic clone" FBgn0039529 CG5612 - http://flybase.org/reports/FBgn0039529 protein_coding_gene - - - CG5612 - CG5612 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0021839 l(2)k15206 lethal (2) k15206 http://flybase.org/reports/FBgn0021839 - gene - - - l(2)k15206 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0036022 CG8329 - http://flybase.org/reports/FBgn0036022 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 sleep ; GO:0030431 | inferred from expression pattern proteolysis ; GO:0006508 | inferred from sequence model" - "SP170, CG8329" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG8329 27-Aug-18 DroID_v2018_08 "Drer\masp2, Drer\zgc:112266" - - - "Mmus\Klk12, Mmus\C1s2, Mmus\Cela1, Mmus\C1s1" "Hsap\KLK7, Hsap\C1S, Hsap\PROC" FBgn0041838 Eth-AR205 Eth-AR205 http://flybase.org/reports/FBgn0041838 gene - - - "Eth[AR]205, Eth-AR205" - - 27-Aug-18 DroID_v2018_08 - - - - - - "chemical resistant,dominant" FBgn0000061 al aristaless http://flybase.org/reports/FBgn0000061 - protein_coding_gene sequence-specific DNA binding ; GO:0043565 | contributes_to inferred from direct assay inferred from physical interaction with C15 "chaeta development ; GO:0022416 | inferred from mutant phenotype imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from mutant phenotype positive regulation of Notch signaling pathway ; GO:0045747 | inferred from expression pattern leg disc development ; GO:0035218 | inferred from mutant phenotype antennal morphogenesis ; GO:0048800 | inferred from mutant phenotype elongation of arista core ; GO:0035015 | inferred from mutant phenotype" protein complex ; GO:0043234 | inferred from physical interaction with C15 "A1, CG3935, L13-4, AL, lambda13-4, al, Al" "IPR017970:Homeobox, conserved site, IPR000047:Helix-turn-helix motif, IPR001356:Homeobox domain, IPR003654:OAR domain, IPR009057:Homeobox domain-like" CG3935 27-Aug-18 DroID_v2018_08 "Drer\pax7b, Drer\hhex, Drer\pax8, Drer\pax5, Drer\pax2b, Drer\arxb, Drer\arxa, Drer\pax9, Drer\pax1b, Drer\pax6a, Drer\rx3, Drer\pax7a, Drer\alx3, Drer\pax3a, Drer\sebox, Drer\alx1, Drer\pax10, Drer\pax2a, Drer\pax1a, Drer\pax6b" Scer\PHO2 "Cele\ceh-54, Cele\alr-1, Cele\pax-1, Cele\eyg-1, Cele\pax-2, Cele\vab-3, Cele\unc-4, Cele\egl-38, Cele\ceh-8" "Xtro\pax8, Xtro\pax6, Xtro\pax2, Xtro\pax1, Xtro\pax9, Xtro\arx, Xtro\pax5, Xtro\alx1, Xtro\pax3, Xtro\pax7" "Mmus\Arx, Mmus\Pax9, Mmus\Pax1, Mmus\Alx3, Mmus\Pax7, Mmus\Sebox, Mmus\Pax8, Mmus\Pax5, Mmus\Pax6, Mmus\Rax, Mmus\Pax4, Mmus\Alx1, Mmus\Pax3, Mmus\Pax2" "Hsap\PAX7, Hsap\ARX, Hsap\ALX4, Hsap\PAX2, Hsap\PAX8, Hsap\PAX5, Hsap\SEBOX, Hsap\PAX3, Hsap\PAX4, Hsap\PAX9, Hsap\PAX1, Hsap\PAX6, Hsap\ALX1, Hsap\ALX3" " larval stage | third instar , embryonic stage | stage >=10 , embryonic stage | stage >=11 , embryonic stage | stage 13 " " ventral thoracic disc | restricted

, embryonic maxillary segment | restricted

, embryonic antennal segment | restricted

, embryonic mandibular segment | restricted

, embryonic labial segment | restricted

, embryonic prothoracic segment | restricted

, embryonic metathoracic segment | restricted

, mesothoracic segment | restricted

, embryonic abdominal segment 1--8

, eye-antennal disc | restricted

, dorsal mesothoracic disc | restricted

" "viable,fertile,wild-type,lethal,recessive,visible,poor,somatic clone,lethal - all die before end of embryonic stage,some die during embryonic stage,mating defective,female,lethal - all die before end of P-stage,some die during pharate adult stage,female sterile,partially lethal - majority die" "wing,ectopic,arista,posterior scutellar bristle,scutellum,sternopleural bristle,unguis,leg,distal,mesothoracic bristle,wing vein L2,somatic clone,pleurum,tarsal segment 4,pretarsus,wing vein L1,thorax,wing vein,eye,adult thorax,macrochaeta & thorax,microchaeta & thorax,wing vein L3,tarsal segment" FBgn0263709 lncRNA:CR43661 - http://flybase.org/reports/FBgn0263709 non_protein_coding_gene - - - CR43661 - CR43661 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0003657 swy swarthy http://flybase.org/reports/FBgn0003657 - gene - - - swy - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive,male fertile,female fertile,fertile,viable,reduced,eye color defective,body color defective" "eye,scutellum,pigment cell" FBgn0001366 l(1)1Fe lethal (1) 1Fe http://flybase.org/reports/FBgn0001366 - gene - - - l(1)1Fe - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0010100 Acon Aconitase http://flybase.org/reports/FBgn0010100 "FBgn0010634, FBgn0032927, FBgn0043824" protein_coding_gene "4 iron, 4 sulfur cluster binding ; GO:0051539 | inferred from electronic annotation with InterPro:IPR006248 aconitate hydratase activity ; GO:0003994 | inferred from sequence or structural similarity aconitate hydratase activity ; GO:0003994 | non-traceable author statement aconitate hydratase activity ; GO:0003994 | inferred from sequence or structural similarity with UniProtKB:Q99798" tricarboxylic acid cycle ; GO:0006099 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q99798 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity "ACON-1, Acon, m-acon, i204, i59, CG9244, FBgn0010100, mAc, AconM, BEST:GH10550, l(2)07054, M-Acon, mAcon, hsp60, mACON, m-Acon, acon" "IPR015928:Aconitase/3-isopropylmalate dehydratase, swivel, IPR015931:Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3, IPR015932:Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2, IPR000573:Aconitase A/isopropylmalate dehydratase small subunit, swivel domain, IPR001030:Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain, IPR006248:Aconitase, mitochondrial-like, IPR018136:Aconitase family, 4Fe-4S cluster binding site" CG9244 27-Aug-18 DroID_v2018_08 Drer\aco2 "Scer\LEU1, Scer\ACO2, Scer\ACO1, Scer\LYS4, Scer\MRPL49" "Cele\aco-1, Cele\aco-2" Xtro\aco2 "Mmus\Ireb2, Mmus\Aco2, Mmus\Aco1" "Hsap\IREB2, Hsap\ACO1, Hsap\ACO2" "lethal - all die during embryonic stage,recessive,lethal,viable,partially lethal,short lived,locomotor behavior defective,increased cell death" "mitochondrionple.PF,embryonic/larval brain | larval stage" FBgn0001755 l(1)M3 lethal (1) M3 http://flybase.org/reports/FBgn0001755 - gene - - - l(1)M3 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" macrochaeta FBgn0044089 E(rst)D70 E(rst)D70 http://flybase.org/reports/FBgn0044089 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "D70, E(rst)D70" - - 27-Aug-18 DroID_v2018_08 - - - - - - viable eye FBgn0051933 CG31933 - http://flybase.org/reports/FBgn0051933 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR017849, InterPro:IPR017850" "metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR017849, InterPro:IPR017850" - "CG15622, CG31933, gi22945479, gi21064045" "IPR004245:Protein of unknown function DUF229, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha, IPR017850:Alkaline-phosphatase-like, core domain" CG31933 27-Aug-18 DroID_v2018_08 - - "Cele\T07G12.3, Cele\M03F8.5, Cele\Y73F8A.35, Cele\F15H10.7, Cele\Y38A10A.2, Cele\Y41E3.1, Cele\F32D8.2, Cele\F07C3.3, Cele\K03A11.4, Cele\R03G8.3, Cele\F32G8.2, Cele\F10C2.3, Cele\R03G8.1, Cele\T23E1.1" - - - viable FBgn0024705 anon-84Ac anon-84Ac http://flybase.org/reports/FBgn0024705 - gene - - - anon-84Ac - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035750 CG14826 - http://flybase.org/reports/FBgn0035750 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14826 IPR006631:Protein of unknown function DM4/12 CG14826 27-Aug-18 DroID_v2018_08 - - - - - - DRSC10197 E 0.468503888 0.018254562 1.552314443 0.424096142 0.637877435 0.918861889 FBgn0015731 Fip2 Ftz-interacting protein 2 http://flybase.org/reports/FBgn0015731 - gene - regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from direct assay - "FIP2, Fip2" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040023 CG12575 - http://flybase.org/reports/FBgn0040023 protein_coding_gene - - - CG12575 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0058120 CG40120 - http://flybase.org/reports/FBgn0058120 protein_coding_gene - - - CG40120 - - 27-Aug-18 DroID_v2018_08 - - - - - - DRSC21163 K 0.548618458 -0.037047855 -0.388348983 0.633041696 1.068674376 1.528002912 FBgn0001753 l(1)jl lethal (1) jawless http://flybase.org/reports/FBgn0001753 - gene - - - l(1)jl - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" cephalopharyngeal skeleton FBgn0001114 Glt Glutactin http://flybase.org/reports/FBgn0001114 - protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from biological aspect of ancestor with PANTHER:PTN000168392 neurexin family protein binding ; GO:0042043 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 receptor activity ; GO:0004872 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 modulation of synaptic transmission ; GO:0050804 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 neuron cell-cell adhesion ; GO:0007158 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype defense response to other organism ; GO:0098542 | inferred from mutant phenotype synapse assembly ; GO:0007416 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 synaptic target inhibition ; GO:0016201 | inferred from mutant phenotype basement membrane ; GO:0005604 | inferred from direct assay synapse ; GO:0045202 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 cell surface ; GO:0009986 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 "CT26441, CG9280, Glt" "IPR002018:Carboxylesterase, type B, IPR019819:Carboxylesterase type B, conserved site, IPR029058:Alpha/Beta hydrolase fold" CG9280 27-Aug-18 DroID_v2018_08 "Drer\nlgn4a, Drer\nlgn3b, Drer\nlgn2a, Drer\ces2, Drer\cell, Drer\nlgn1, Drer\nlgn2b, Drer\cel.1, Drer\ces3, Drer\nlgn3a, Drer\nlgn4b, Drer\si:ch211-93f2.1" - "Cele\C23H4.2, Cele\K11G9.2, Cele\T07H6.1, Cele\C01B10.4, Cele\nlg-1, Cele\E01G6.3, Cele\C23H4.3, Cele\ZK994.1, Cele\B0238.7, Cele\T22D1.11, Cele\ZC376.1, Cele\F55F3.2, Cele\Y71H2AM.13, Cele\C42D4.2, Cele\ZC376.2, Cele\K07C11.4, Cele\C23H4.7, Cele\T02B5.1, Cele\K11G9.1, Cele\ges-1, Cele\F15A8.6, Cele\C52A10.2, Cele\Y75B8A.3, Cele\F07C4.12, Cele\R173.3, Cele\glit-1, Cele\ZC376.3, Cele\F13H6.3, Cele\K11G9.3, Cele\T02B5.3, Cele\W02B12.4, Cele\F56C11.6" "Xtro\LOC100494782, Xtro\ces2, Xtro\nlgn2, Xtro\cel, Xtro\ces3, Xtro\nlgn3, Xtro\nlgn4x" "Mmus\Ces2a, Mmus\Ces1e, Mmus\Ces1f, Mmus\Ces2h, Mmus\Ces1c, Mmus\Ces3a, Mmus\Ces4a, Mmus\Ces1h, Mmus\Ces5a, Mmus\Ces2g, Mmus\Ces2c, Mmus\Ces2f, Mmus\Ces2e, Mmus\Ces1d, Mmus\Ces2b, Mmus\Ces3b, Mmus\Nlgn1, Mmus\Ces1g, Mmus\Cel, Mmus\Nlgn3, Mmus\Ces1b, Mmus\Nlgn2" "Hsap\NLGN3, Hsap\CES5A, Hsap\NLGN4Y, Hsap\CES2, Hsap\CES1, Hsap\NLGN4X, Hsap\CES3, Hsap\NLGN1, Hsap\NLGN2, Hsap\CEL, Hsap\CES4A" embryonic stage " dorsal neurohemal organ

, embryonic central nervous system

, apodeme

" "immune response defective,viable,short lived,conditional" FBgn0266438 PIG-Z Phosphatidylinositol glycan anchor biosynthesis class Z http://flybase.org/reports/FBgn0266438 protein_coding_gene "alpha-1,2-mannosyltransferase activity ; GO:0000026 | inferred from sequence or structural similarity with UniProtKB:Q86VD9 mannosyltransferase activity ; GO:0000030 | inferred from sequence or structural similarity with HGNC:30596 mannosyltransferase activity ; GO:0000030 | inferred from biological aspect of ancestor with PANTHER:PTN000509188" GPI anchor biosynthetic process ; GO:0006506 | inferred from sequence or structural similarity with HGNC:30596 GPI anchor biosynthetic process ; GO:0006506 | inferred from sequence or structural similarity with UniProtKB:Q86VD9 GPI anchor biosynthetic process ; GO:0006506 | inferred from biological aspect of ancestor with PANTHER:PTN001101712 endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000509188 endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with HGNC:30596 endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with UniProtKB:Q86VD9 "CG3419, PIG-Z, CG45068" IPR005599:GPI mannosyltransferase CG45068 27-Aug-18 DroID_v2018_08 - Scer\SMP3 Cele\eif-1 - Mmus\Pigz Hsap\PIGZ FBgn0040923 CG11368 - http://flybase.org/reports/FBgn0040923 protein_coding_gene - - - "BcDNA:RH67809, CG11368" - CG11368 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,some die during pupal stage" FBgn0051793 CG31793 - http://flybase.org/reports/FBgn0051793 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR011527, InterPro:IPR017871 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from biological aspect of ancestor with PANTHER:PTN000657997" transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000657997 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000658000 "CG17338, CG10441, CG31793" "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR011527:ABC transporter type 1, transmembrane domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR017871:ABC transporter, conserved site" CG31793 27-Aug-18 DroID_v2018_08 "Drer\abcc2, Drer\cftr, Drer\abcc4, Drer\abcc8, Drer\abcc9, Drer\abcc1, Drer\abcc3, Drer\abcc6a, Drer\abcc5, Drer\abcc6b.2, Drer\abcc10, Drer\abcc12, Drer\LOC100329706, Drer\abcc13" "Scer\BPT1, Scer\NFT1, Scer\STE6, Scer\YCF1, Scer\YBT1, Scer\YKR104W, Scer\VMR1, Scer\YOR1" "Cele\mrp-1, Cele\mrp-8, Cele\mrp-7, Cele\mrp-4, Cele\mrp-2, Cele\mrp-3, Cele\mrp-5, Cele\mrp-6" "Xtro\abcc1, Xtro\abcc4, Xtro\abcc10, Xtro\abcc3, Xtro\abcc6, Xtro\cftr" "Mmus\Abcc3, Mmus\Abcc9, Mmus\Abcc6, Mmus\Abcc2, Mmus\Abcc12, Mmus\Abcc1, Mmus\Cftr, Mmus\Abcc10, Mmus\Abcc5, Mmus\Abcc4, Mmus\Abcc8" "Hsap\CFTR, Hsap\ABCC3, Hsap\ABCC6, Hsap\ABCC12, Hsap\ABCC8, Hsap\ABCC2, Hsap\ABCC10, Hsap\ABCC9, Hsap\ABCC4, Hsap\ABCC1, Hsap\ABCC5, Hsap\ABCC11" "viable,visible" trichogen cell FBgn0261439 SdhA "Succinate dehydrogenase, subunit A (flavoprotein)" http://flybase.org/reports/FBgn0261439 protein_coding_gene "flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR011281, InterPro:IPR014006 electron carrier activity ; GO:0009055 | inferred from biological aspect of ancestor with PANTHER:PTN000180228 succinate dehydrogenase (ubiquinone) activity ; GO:0008177 | inferred from biological aspect of ancestor with PANTHER:PTN000180259 succinate dehydrogenase (ubiquinone) activity ; GO:0008177 | inferred from sequence or structural similarity with UniProtKB:P31040" "mitochondrial electron transport, succinate to ubiquinone ; GO:0006121 | inferred from biological aspect of ancestor with PANTHER:PTN000180258 tricarboxylic acid cycle ; GO:0006099 | inferred from biological aspect of ancestor with PANTHER:PTN000180364 tricarboxylic acid cycle ; GO:0006099 | inferred from sequence or structural similarity with UniProtKB:P31040 anaerobic respiration ; GO:0009061 | inferred from biological aspect of ancestor with PANTHER:PTN000180228 electron transport chain ; GO:0022900 | inferred from mutant phenotype" "mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) ; GO:0005749 | inferred from biological aspect of ancestor with PANTHER:PTN000180258 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) ; GO:0005749 | inferred from sequence or structural similarity with UniProtKB:P31040 mitochondrion ; GO:0005739 | inferred from direct assay" "CG17246, SdhA, sdh, Sdh, scs-fp, Scs-fp, Sdha, SDH, DHSA, Sdh A" "IPR015939:Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal, IPR003952:Fumarate reductase/succinate dehydrogenase, FAD-binding site, IPR003953:FAD-dependent oxidoreductase 2, FAD binding domain, IPR011281:Succinate dehydrogenase, flavoprotein subunit, IPR014006:Succinate dehydrogenase/fumarate reductase, flavoprotein subunit, IPR027477:Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain, IPR030664:Succinate dehydrogenase/fumarate reductase/adenylylsulphate reductase, flavoprotein subunit, IPR023753:FAD/NAD(P)-binding domain" CG17246 27-Aug-18 DroID_v2018_08 Drer\sdha "Scer\OSM1, Scer\FRD1, Scer\YJL045W, Scer\SDH1" "Cele\sdha-1, Cele\sdha-2" Xtro\sdha Mmus\Sdha Hsap\SDHA DRSC07547 K 0.481089811 0.281303705 0.38404312 0.469883919 0.229441572 1.642228504 FBgn0044349 ftz-f1::Hsap\NR5A1 NR5A1 http://flybase.org/reports/FBgn0044349 engineered_fusion_gene - - - ftz-f1::Hsap\NR5A1 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004952 1688-10Eb 1.688 satellite-related 10Eb http://flybase.org/reports/FBgn0004952 - repeat_region - - - "1.688, 1688-10E[p], 1688-10Eb" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037326 CG14669 - http://flybase.org/reports/FBgn0037326 protein_coding_gene "GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR001806 GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR020849 molecular_function ; GO:0003674 | no biological data available" signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR020849 biological_process ; GO:0008150 | no biological data available membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR020849 cellular_component ; GO:0005575 | no biological data available "CG14669, Q9VNB7" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR001806:Small GTPase superfamily, IPR020849:Small GTPase superfamily, Ras type" CG14669 27-Aug-18 DroID_v2018_08 "Drer\LOC100332969, Drer\rap2ab, Drer\rap1ab, Drer\rergla, Drer\rit1, Drer\rsg1, Drer\rap2c, Drer\zgc:64022, Drer\zgc:110699, Drer\rerglb, Drer\diras1a, Drer\rasl11a, Drer\ralaa, Drer\ralab, Drer\zgc:152698, Drer\rem1, Drer\rhebl1, Drer\rras2, Drer\si:ch73-116o1.2, Drer\si:dkeyp-59c12.1, Drer\zgc:114118, Drer\gem, Drer\rras, Drer\kras, Drer\rrad, Drer\rasl11b, Drer\rap2b, Drer\ralba, Drer\rap1aa, Drer\mras, Drer\si:dkey-27j5.5, Drer\zgc:153845, Drer\hrasa, Drer\rasl10a, Drer\ralbb, Drer\nras, Drer\diras2, Drer\rheb, Drer\rasd1, Drer\rem2, Drer\diras1b, Drer\rasl12, Drer\hrasb, Drer\zgc:171704" "Scer\RAS2, Scer\RSR1, Scer\RHB1, Scer\RAS1" - "Xtro\rhebl1, Xtro\rem1, Xtro\rasd1, Xtro\rsg1, Xtro\rasl11b, Xtro\diras1, Xtro\rap1b, Xtro\rap2a, Xtro\rasl10a, Xtro\ralb, Xtro\rem2, Xtro\rala, Xtro\kras, Xtro\rergl, Xtro\hras, Xtro\LOC733456, Xtro\nras, Xtro\rap2c, Xtro\gem, Xtro\rheb, Xtro\rerg, Xtro\rasl10b, Xtro\diras2, Xtro\diras3, Xtro\rap2b, Xtro\rit1, Xtro\rap1a, Xtro\ras-dva, Xtro\rrad, Xtro\rasd2" "Mmus\Rhebl1, Mmus\Rap2b, Mmus\Kras, Mmus\Rap2a, Mmus\Rrad, Mmus\Rsg1, Mmus\Rasl11a, Mmus\Rala, Mmus\Rem1, Mmus\Rergl, Mmus\Rasl11b, Mmus\Rit1, Mmus\Rap2c, Mmus\Nras, Mmus\Rheb, Mmus\Diras2, Mmus\Rasl12, Mmus\Gm266, Mmus\Rras2, Mmus\Rasl10b, Mmus\Gem, Mmus\Rit2, Mmus\Hras, Mmus\Rap1b, Mmus\Rras, Mmus\Rasl10a, Mmus\Mras, Mmus\Rap1a, Mmus\Rem2, Mmus\Rerg, Mmus\Eras, Mmus\Rasd1, Mmus\Diras1, Mmus\Rasd2, Mmus\Ralb" "Hsap\GEM, Hsap\RIT1, Hsap\RERGL, Hsap\RAP1B, Hsap\ERAS, Hsap\RASL10B, Hsap\RAP1A, Hsap\RAP2A, Hsap\RHEBL1, Hsap\RRAS, Hsap\RASL11B, Hsap\RASL10A, Hsap\RHEB, Hsap\RRAD, Hsap\MRAS, Hsap\RALB, Hsap\RRAS2, Hsap\RAP2B, Hsap\RALA, Hsap\RASD1, Hsap\KRAS, Hsap\RASD2, Hsap\REM2, Hsap\NRAS, Hsap\RASL12, Hsap\HRAS, Hsap\DIRAS3, Hsap\RERG, Hsap\RSG1, Hsap\REM1, Hsap\DIRAS1, Hsap\RAP2C, Hsap\DIRAS2, Hsap\RASL11A, Hsap\RIT2" "viable,fertile" DRSC12255 I -0.034507484 1.706376879 1.404762645 -0.663469201 0.344725916 0.685751255 FBgn0085572 CG41246 - http://flybase.org/reports/FBgn0085572 protein_coding_gene - - - CG41246 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0013234 E(var)188 E(var)188 http://flybase.org/reports/FBgn0013234 - gene - - - E(var)188 - - 27-Aug-18 DroID_v2018_08 - - - - - - "enhancer of variegation,dominant" FBgn0026349 Su(da[lyh])22C6 Su(da[lyh])22C6 http://flybase.org/reports/FBgn0026349 - gene - - - "Su(da[lyh]), Su(da[lyh])22C6" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060794 l(3)S058412 lethal (3) S058412 http://flybase.org/reports/FBgn0060794 gene - - - "0584/12, l(3)S058412" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0027155 l(3)31-1 lethal (3) 31-1 http://flybase.org/reports/FBgn0027155 - gene - - - l(3)31-1 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0022707 Agi Aryl glucosidase incognita http://flybase.org/reports/FBgn0022707 - gene "alpha-1,4-glucosidase activity ; GO:0004558 | inferred from direct assay" - - "AGI, Agi" - - 27-Aug-18 DroID_v2018_08 - - - - - - "electrophoretic variant,fast,slow" FBgn0027346 fs(2)58g fs(2)58g http://flybase.org/reports/FBgn0027346 FBgn0000962 gene - - - "fs(2)[58g], fs(2)58g" - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,female sterile,recessive,male fertile" egg FBgn0003688 tft tufts http://flybase.org/reports/FBgn0003688 - gene - - - tft - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile,visible,cold sensitive" FBgn0002373 l(3)91Fe lethal (3) 91Fe http://flybase.org/reports/FBgn0002373 FBgn0002377 gene - - - "l(DIX43)c, C5, l(3)C4-9, l(3)C4-7, l(3)C4-4, l(3)C4-18, l(3)BE81, l(3)BE80, l(3)92Ac, l(3)91Fe" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0061058 l(3)S022527 lethal (3) S022527 http://flybase.org/reports/FBgn0061058 gene - - - "0225/27, l(3)S022527" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0086022 snoRNA:Me28S-U1130 - http://flybase.org/reports/FBgn0086022 snoRNA_gene - - - "snoRNA:Me28S-U1130, Me28S-Um1130, CR34651" - CR34651 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260289 GSd017 - http://flybase.org/reports/FBgn0260289 gene - - - GSd017 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0020361 anon-1D2 anon-1D2 http://flybase.org/reports/FBgn0020361 - gene - - - "1D2, anon-1D2" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0052354 CG32354 - http://flybase.org/reports/FBgn0052354 protein_coding_gene - - - "CG17355, CK01670, BEST:CK01670, CG7159, CG7027, CG32354" IPR002350:Kazal domain CG32354 27-Aug-18 DroID_v2018_08 "Drer\fstl1a, Drer\agrn, Drer\fsta, Drer\fstl1b" - "Cele\ZK813.6, Cele\agr-1, Cele\F29G6.1" "Xtro\fstl1, Xtro\fst" "Mmus\Tmeff2, Mmus\Tmeff1, Mmus\Fst, Mmus\Spink6, Mmus\Spink5, Mmus\Agrn, Mmus\Spink12, Mmus\Fstl1" "Hsap\FST, Hsap\SPINK6, Hsap\AGRN, Hsap\MSANTD3-TMEFF1, Hsap\FSTL1, Hsap\SPINK5, Hsap\TMEFF2" viable FBgn0002216 l(3)67BDn lethal (3) 67BDn http://flybase.org/reports/FBgn0002216 - gene - - - l(3)67BDn - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0286007 mir-281-2 mir-281-2 stem loop http://flybase.org/reports/FBgn0262423 miRNA_gene - - - "mir-281, 281-2, mir-281-2, miR-281-2, MIR-281, CR42975, CR33596, miR-281b, mir-281b, miR-281, CR33593, dme-mir-281-2, CR33597, mir-281-2*, miR-281bS, mir-281bS, miR-281-2-star, dme-miR-281, dme-miR-281-2-5p, dme-miR-281-2" - CR42975 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible" wing margin FBgn0044417 Scim10 Sensitized chromosome inheritance modifier 10 http://flybase.org/reports/FBgn0044417 gene - female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype - Scim10 - - 27-Aug-18 DroID_v2018_08 - - - - - - "meiotic cell cycle defective,dominant" FBgn0040755 CG17580 - http://flybase.org/reports/FBgn0040755 protein_coding_gene - - - "BcDNA:AT18054, CG17580" - CG17580 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0069984 BG02257 BG02257 http://flybase.org/reports/FBgn0069984 gene - - - BG02257 - - 27-Aug-18 DroID_v2018_08 - - - - - - "stress response defective,long lived,female,male,heat stress response defective,starvation stress response defective" FBgn0265842 lncRNA:CR44631 - http://flybase.org/reports/FBgn0265842 non_protein_coding_gene - - - CR44631 - CR44631 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0063404 l(3)CG3 lethal (3) CG3 http://flybase.org/reports/FBgn0063404 gene - - - l(3)CG3 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0053179 beat-IIIb beat-IIIb http://flybase.org/reports/FBgn0053179 protein_coding_gene molecular_function ; GO:0003674 | no biological data available heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0007157 | inferred from sequence or structural similarity with beat-Ic - "beat IIIb, CG4855, CG15135, CG33179, beat-IIIb, Beat-IIIb" "IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold" CG33179 27-Aug-18 DroID_v2018_08 "Drer\jam2b, Drer\f11r.2, Drer\zgc:172106" - - Xtro\f11r - Hsap\CADM2 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0038536 CG7655 - http://flybase.org/reports/FBgn0038536 protein_coding_gene - lateral inhibition ; GO:0046331 | inferred from mutant phenotype nuclear envelope ; GO:0005635 | inferred from sequence or structural similarity with UniProtKB:Q8IXM6 CG7655 IPR033580:Nurim-like CG7655 27-Aug-18 DroID_v2018_08 Drer\nrm - - Xtro\nrm Mmus\Nrm "Hsap\NRM, Hsap\ICMT" "viable,visible" chaeta FBgn0027280 l(1)G0193 lethal (1) G0193 http://flybase.org/reports/FBgn0027280 "FBgn0029064, FBgn0029984" protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "l(1)G0327, CG2206, l(1)G0193" IPR032062:Protein of unknown function DUF4803 CG2206 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,viable" FBgn0266130 144Y - http://flybase.org/reports/FBgn0266130 gene - gravitaxis ; GO:0042332 | inferred from mutant phenotype - 144Y - - 27-Aug-18 DroID_v2018_08 - - - - - - gravitaxis defective FBgn0067374 l(2)NC133 lethal (2) NC133 http://flybase.org/reports/FBgn0067374 gene - - - "NC133, l(2)NC133" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0259646 B1520 - http://flybase.org/reports/FBgn0259646 gene - - - B1520 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible wing FBgn0030085 CG6999 - http://flybase.org/reports/FBgn0030085 protein_coding_gene RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000267771 "endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000472 | inferred from biological aspect of ancestor with PANTHER:PTN000267771 small-subunit processome assembly ; GO:0034462 | inferred from biological aspect of ancestor with PANTHER:PTN000267771 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000447 | inferred from biological aspect of ancestor with PANTHER:PTN000267771 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000480 | inferred from biological aspect of ancestor with PANTHER:PTN000267771 regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype" nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000267771 nucleus ; GO:0005634 | inferred by curator from GO:0000381 CG6999 "IPR000504:RNA recognition motif domain, IPR034353:ABT1/ESF2, RNA recognition motif" CG6999 27-Aug-18 DroID_v2018_08 Drer\abt1 Scer\ESF2 Cele\F57B10.8 Xtro\abt1 Mmus\Abt1 Hsap\ABT1 FBgn0003496 square square http://flybase.org/reports/FBgn0003496 - gene - - - "sq, square" - - 27-Aug-18 DroID_v2018_08 - - - - - - wing FBgn0085523 Su(Ste):CR40820 - http://flybase.org/reports/FBgn0085523 non_protein_coding_gene - - - "CG40820, Su(Ste):CR40820, CR40820" - CR40820 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038547 CG17803 - http://flybase.org/reports/FBgn0038547 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG17803 "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type" CG17803 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-262g12.7, Drer\znf1070, Drer\LOC100537572, Drer\zbtb39, Drer\LOC100538201, Drer\LOC100536312, Drer\znf687a, Drer\znf1078, Drer\znf1069, Drer\LOC100333583, Drer\si:ch73-266f23.3, Drer\si:dkeyp-53d3.5, Drer\LOC100537450, Drer\si:dkey-217d24.6, Drer\znf1159, Drer\LOC100537891, Drer\zgc:113135, Drer\znf1072, Drer\prdm2a, Drer\znf1177, Drer\zgc:173714, Drer\si:dkey-1b17.5, Drer\si:ch211-255f4.1, Drer\LOC100534892, Drer\LOC101883642, Drer\znf407, Drer\znf1073, Drer\LOC100537066, Drer\zgc:174703, Drer\LOC100149007, Drer\LOC108179202, Drer\LOC108184006, Drer\zgc:162948, Drer\znf995, Drer\prdm2b, Drer\zgc:173624, Drer\znf592, Drer\znf1053, Drer\LOC103910931, Drer\LOC100537431, Drer\mynn, Drer\si:dkey-30f3.2, Drer\si:dkey-237m9.1, Drer\si:ch211-226o13.2, Drer\znf1079, Drer\LOC100534765, Drer\LOC100536110, Drer\LOC569391, Drer\znf1077, Drer\zgc:174704, Drer\gb:am422109, Drer\znf408, Drer\LOC100536900, Drer\znf644a, Drer\LOC108182424, Drer\si:ch211-212k5.4, Drer\si:dkeyp-35e5.9, Drer\hnrnpa0l, Drer\si:dkey-7i4.5, Drer\LOC100536649, Drer\znf1167, Drer\znf644b, Drer\si:dkey-20i20.2, Drer\znf687b, Drer\znf569l, Drer\LOC100333857, Drer\LOC100150619, Drer\zgc:174314, Drer\si:ch211-255f4.3, Drer\LOC101882607, Drer\LOC100149645, Drer\znf1043, Drer\zbtb17, Drer\zgc:173713, Drer\znf1147, Drer\znf1041, Drer\znf1171, Drer\znf1040, Drer\znf319, Drer\LOC108183429, Drer\LOC100332458, Drer\zbtb41, Drer\znf1059, Drer\znf1068, Drer\znf507, Drer\znf1173, Drer\LOC103910994, Drer\si:dkeyp-104f11.6, Drer\si:ch211-194b1.1, Drer\zgc:173716, Drer\zgc:174315, Drer\znf1181, Drer\zgc:173705, Drer\LOC100537352, Drer\LOC101882787, Drer\LOC101885193, Drer\LOC101882721, Drer\LOC100329723, Drer\LOC100535113, Drer\prdm4, Drer\zgc:174696, Drer\si:dkeyp-35e5.10, Drer\LOC108183430, Drer\LOC101885678, Drer\si:ch211-162i8.2, Drer\si:ch211-223a21.4" Scer\AZF1 "Cele\lin-29, Cele\C27A12.2, Cele\Y53H1A.2, Cele\M03D4.4, Cele\zfp-2, Cele\K11D2.4, Cele\Y55F3AM.14, Cele\ztf-3, Cele\klu-1, Cele\F58G1.2" - "Mmus\4930522L14Rik, Mmus\Zfp951, Mmus\Zfp746, Mmus\Zfp777, Mmus\Zfp398, Mmus\Zfp820, Mmus\Zbtb41, Mmus\Zfp758, Mmus\Zfp946, Mmus\Zfp644, Mmus\Zfp867, Mmus\Zfp868, Mmus\Zfp408, Mmus\Zfp120, Mmus\Zfp108, Mmus\Zfp786, Mmus\AU041133, Mmus\Zfp944, Mmus\Zfp407, Mmus\Zfp984, Mmus\Zfp429, Mmus\Zfp426, Mmus\Zkscan7, Mmus\Zfp61, Mmus\Gm20939, Mmus\Zfp872, Mmus\Zbtb39, Mmus\Zfp942, Mmus\Zfp472, Mmus\Zfp960, Mmus\Zfp563, Mmus\Zfp287, Mmus\Zbtb17, Mmus\Zfp981, Mmus\Zfp467, Mmus\Zfp985, Mmus\Prdm4, Mmus\Prdm2, Mmus\Zfp507, Mmus\Zfp109, Mmus\Zfp646, Mmus\Zfp870, Mmus\Zfp534, Mmus\Zfp932, Mmus\Zfp982, Mmus\Gm4767, Mmus\Zfp57, Mmus\Gzf1, Mmus\Gm10778, Mmus\Zfp784, Mmus\Zfp992, Mmus\Zfp987, Mmus\Zfp592, Mmus\Zfp943, Mmus\Gm14432, Mmus\Zfp114, Mmus\Zfp947, Mmus\Zfp445, Mmus\Zfp866, Mmus\Zfp697, Mmus\Zfp768, Mmus\Zfp871, Mmus\Zfp687, Mmus\Zfp980, Mmus\Zfp93, Mmus\Zfp979, Mmus\Zfp597, Mmus\Rex2, Mmus\Zfp991, Mmus\Zfp94, Mmus\Zfp97, Mmus\Zfp319, Mmus\Zfp462, Mmus\Zfp995, Mmus\Rsl1, Mmus\Mynn" "Hsap\ZNF136, Hsap\ZNF646, Hsap\ZNF527, Hsap\ZBTB41, Hsap\GZF1, Hsap\ZFP57, Hsap\PRDM2, Hsap\ZBTB17, Hsap\ZNF786, Hsap\ZNF426, Hsap\PRDM4, Hsap\ZNF547, Hsap\ZNF398, Hsap\ZNF530, Hsap\ZNF507, Hsap\ZNF333, Hsap\ZNF230, Hsap\ZNF462, Hsap\ZNF776, Hsap\ZNF416, Hsap\ZNF287, Hsap\ZNF697, Hsap\ZNF17, Hsap\ZNF407, Hsap\ZNF587, Hsap\ZNF592, Hsap\ZNF852, Hsap\ZNF34, Hsap\ZNF155, Hsap\ZNF597, Hsap\ZNF467, Hsap\ZNF644, Hsap\ZNF774, Hsap\ZNF746, Hsap\ZNF8, Hsap\ZNF670, Hsap\ZNF445, Hsap\MYNN, Hsap\ZNF687, Hsap\ZNF806, Hsap\ZNF417, Hsap\ZKSCAN7, Hsap\ZNF768, Hsap\ZNF777, Hsap\ZBTB39, Hsap\ZNF408, Hsap\ZNF285, Hsap\ZNF707, Hsap\ZNF222, Hsap\ZNF223, Hsap\ZNF319, Hsap\ZNF281, Hsap\ZNF784, Hsap\ZNF214" viable DRSC22811 E 0.062826746 0.126168717 -0.893777183 -2.651257869 0.626585416 0.745671747 FBgn0263091 CR43359 - http://flybase.org/reports/FBgn0263091 pseudogene_attribute - - - CR43359 - CR43359 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000374 cripC crippled C http://flybase.org/reports/FBgn0000374 - gene - - - cripC - - 27-Aug-18 DroID_v2018_08 - - - - - - "behavior defective,uncoordinated" leg FBgn0035160 hng3 hinge3 http://flybase.org/reports/FBgn0035160 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR004210 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN001073606 transcription coactivator activity ; GO:0003713 | inferred from biological aspect of ancestor with PANTHER:PTN001073606 basal RNA polymerase II transcription machinery binding ; GO:0001099 | inferred from biological aspect of ancestor with PANTHER:PTN001073606" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from biological aspect of ancestor with PANTHER:PTN001073606" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001073606 "anon-WO0118547.557, CG13897, hng3" "IPR004210:BESS motif, IPR006578:MADF domain" CG13897 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-207i20.3, Drer\zgc:152938" - "Cele\madf-3, Cele\madf-4, Cele\madf-9" - - - "flightless,viable" wing hinge FBgn0014102 anon-4Ca anon-4Ca http://flybase.org/reports/FBgn0014102 - gene - - - "T3, anon-4Ca" - - 27-Aug-18 DroID_v2018_08 - - - - - - adult stage adult head

FBgn0265975 hbs::sns - http://flybase.org/reports/FBgn0265975 engineered_fusion_gene - - - hbs::sns - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0041586 mei-217::mei-218 mei-217::mei-218 http://flybase.org/reports/FBgn0041586 engineered_fusion_gene - - - mei-217::mei-218 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267656 lncRNA:CR45994 - http://flybase.org/reports/FBgn0267656 non_protein_coding_gene - - - CR45994 - CR45994 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065229 l(2)SH2184 lethal (2) SH2184 http://flybase.org/reports/FBgn0065229 gene - - - "l(2)SH2184, l(2)SH2 2184" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0014223 l(2)31Eb lethal (2) 31Eb http://flybase.org/reports/FBgn0014223 - gene - - - l(2)31Eb - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0001241 hy humpy http://flybase.org/reports/FBgn0001241 - gene - - - hy - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,reduced,female sterile,male sterile" adult thorax FBgn0038166 CG9588 - http://flybase.org/reports/FBgn0038166 protein_coding_gene - proteasome regulatory particle assembly ; GO:0070682 | inferred from biological aspect of ancestor with PANTHER:PTN000291528 cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype "cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000291528 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000291528 proteasome regulatory particle, base subcomplex ; GO:0008540 | inferred from biological aspect of ancestor with PANTHER:PTN000291528" "CG9588, 9588, dp27, p27" IPR001478:PDZ domain CG9588 27-Aug-18 DroID_v2018_08 Drer\psmd9 Scer\NAS2 Cele\psmd-9 Xtro\psmd9 Mmus\Psmd9 Hsap\PSMD9 viable FBgn0267470 lncRNA:CR45820 - http://flybase.org/reports/FBgn0267470 non_protein_coding_gene - - - CR45820 - CR45820 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060415 l(3)S129615 lethal (3) S129615 http://flybase.org/reports/FBgn0060415 gene - - - "1296/15, l(3)S129615" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0040734 CG15065 - http://flybase.org/reports/FBgn0040734 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "defense response ; GO:0006952 | inferred from sequence or structural similarity with IM2, IM1" extracellular space ; GO:0005615 | inferred from sequence model "CT34936, IM2-like, CG15065" IPR013172:Immune-induced protein Dim CG15065 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0265527 lncRNA:CR44377 - http://flybase.org/reports/FBgn0265527 non_protein_coding_gene - - - "CR44377, lincRNA.329" - CR44377 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037057 CG10512 - http://flybase.org/reports/FBgn0037057 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR003767 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR003767 - CG10512 IPR003767:Malate/L-lactate dehydrogenase CG10512 27-Aug-18 DroID_v2018_08 - - "Cele\VF13D12L.3, Cele\F36A2.3" - - - "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0051706 CG31706 - http://flybase.org/reports/FBgn0051706 protein_coding_gene - - - "CG6528, CG31706" IPR032086:Protein of unknown function DUF4813 CG31706 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,some die during pupal stage" FBgn0028400 Syt4 Synaptotagmin 4 http://flybase.org/reports/FBgn0028400 protein_coding_gene "phosphatidylserine binding ; GO:0001786 | inferred from direct assay calcium-dependent phospholipid binding ; GO:0005544 | inferred from direct assay calcium-dependent phospholipid binding ; GO:0005544 | non-traceable author statement SNARE binding ; GO:0000149 | inferred from physical interaction with Snap25, Syx1A syntaxin binding ; GO:0019905 | inferred from biological aspect of ancestor with PANTHER:PTN000001285 clathrin binding ; GO:0030276 | inferred from biological aspect of ancestor with PANTHER:PTN000001285" positive regulation of vesicle fusion ; GO:0031340 | inferred from direct assay vesicle-mediated transport ; GO:0016192 | non-traceable author statement neurotransmitter secretion ; GO:0007269 | non-traceable author statement synaptic vesicle exocytosis ; GO:0016079 | inferred from sequence or structural similarity calcium ion-regulated exocytosis of neurotransmitter ; GO:0048791 | inferred from biological aspect of ancestor with PANTHER:PTN000001285 regulation of synaptic plasticity ; GO:0048167 | inferred from mutant phenotype regulation of neurotransmitter secretion ; GO:0046928 | inferred from mutant phenotype neuromuscular junction ; GO:0031594 | inferred from direct assay vesicle ; GO:0031982 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model synaptic vesicle ; GO:0008021 | inferred from sequence or structural similarity postsynaptic membrane ; GO:0045211 | inferred from direct assay apical plasma membrane ; GO:0016324 | inferred from direct assay "Syt4, syt4, dsyt4, sytIV, SYT4, D.Syt IV, CG10047, SytIV, syt 4, Syt IV" "IPR000008:C2 domain, IPR001565:Synaptotagmin" CG10047 27-Aug-18 DroID_v2018_08 "Drer\syt10, Drer\si:ch211-266g18.6, Drer\syt17, Drer\syt11b, Drer\syt3, Drer\syt5a, Drer\syt11a, Drer\sytl5, Drer\syt5b, Drer\syt9b, Drer\pla2g4f.1, Drer\sytl1, Drer\pla2g4f.2, Drer\syt4, Drer\syt9a, Drer\tc2n, Drer\syt2a, Drer\sytl2a, Drer\syt1b" - Cele\snt-4 "Xtro\jmjd7-pla2g4b, Xtro\pla2g4f, Xtro\syt3, Xtro\syt4" "Mmus\Syt17, Mmus\Syt8, Mmus\Syt2, Mmus\Syt11, Mmus\Syt15, Mmus\Syt4, Mmus\Pla2g4e, Mmus\Sytl3, Mmus\Sytl2, Mmus\Syt9, Mmus\Tc2n, Mmus\Pla2g4d, Mmus\Pla2g4f, Mmus\Syt10, Mmus\Sytl4, Mmus\Pla2g4b, Mmus\Syt5" "Hsap\SYT9, Hsap\PLA2G4E, Hsap\SYTL2, Hsap\SYT17, Hsap\SYT4, Hsap\SYT5, Hsap\SYT2, Hsap\SYTL4, Hsap\SYTL3, Hsap\SYT16, Hsap\TC2N, Hsap\SYT10, Hsap\SYT7, Hsap\PLA2G4D, Hsap\PLA2G4F, Hsap\PLA2G4B, Hsap\SYT11, Hsap\SYT15, Hsap\SYT8" embryonic stage " neuron

, embryonic central nervous system

" adult stage neuron

"visible,neurophysiology defective,neuroanatomy defective,viable,fertile" "wing vein,neuromuscular junctionMhc.PW,NMJ bouton,neuromuscular junction,motor neuron,neuromuscular junctionrn16),neuromuscular junctionelav.PLu" FBgn0011609 l(1)I33d25 lethal (1) I33d25 http://flybase.org/reports/FBgn0011609 FBgn0010206 gene - - - "l(1)33d25, l(1)I33d25" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0069300 agho aghino http://flybase.org/reports/FBgn0069300 gene - - - agho - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030271 CG15202 - http://flybase.org/reports/FBgn0030271 protein_coding_gene - defense response to virus ; GO:0051607 | inferred from biological aspect of ancestor with PANTHER:PTN002219240 extracellular space ; GO:0005615 | inferred from sequence model "BcDNA:GH13342, CG15202, DIGF-4" IPR029277:Single domain Von Willebrand factor type C domain CG15202 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0043353 EP3104 EP3104 http://flybase.org/reports/FBgn0043353 gene - - - EP3104 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "eye,dorsocentral bristle,scutellar bristle,trichogen cell,ectopic,tormogen cell" FBgn0263755 Su(var)3-9 Suppressor of variegation 3-9 http://flybase.org/reports/FBgn0263755 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR003606, InterPro:IPR007728 histone methyltransferase activity ; GO:0042054 | inferred from direct assay histone methyltransferase activity (H3-K9 specific) ; GO:0046974 | traceable author statement histone methyltransferase activity ; GO:0042054 | non-traceable author statement histone methyltransferase activity (H3-K9 specific) ; GO:0046974 | inferred from direct assay" histone H3-K9 methylation ; GO:0051567 | inferred from direct assay histone methylation ; GO:0016571 | inferred from direct assay heterochromatin organization involved in chromatin silencing ; GO:0070868 | inferred from mutant phenotype chromatin silencing ; GO:0006342 | inferred from mutant phenotype gene silencing ; GO:0016458 | traceable author statement female germ-line stem cell asymmetric division ; GO:0048132 | inferred from direct assay histone methylation ; GO:0016571 | traceable author statement histone modification ; GO:0016570 | inferred from mutant phenotype histone H3-K9 methylation ; GO:0051567 | inferred from mutant phenotype chromatin organization ; GO:0006325 | non-traceable author statement heterochromatin assembly ; GO:0031507 | inferred from mutant phenotype gene silencing ; GO:0016458 | inferred from mutant phenotype chromosome organization ; GO:0051276 | inferred from mutant phenotype chromatin silencing at telomere ; GO:0006348 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype negative regulation of response to gamma radiation ; GO:2001229 | inferred from mutant phenotype DNA methylation ; GO:0006306 | inferred from mutant phenotype chromatin organization ; GO:0006325 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from direct assay "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR003606, InterPro:IPR007728, InterPro:IPR011381 chromosome, centromeric region ; GO:0000775 | traceable author statement heterochromatin ; GO:0000792 | traceable author statement heterochromatin ; GO:0000792 | inferred from direct assay polytene chromosome chromocenter ; GO:0005701 | inferred from direct assay" "SU(VAR)3-9, Su(var)3-9, E(var)3-2, ptn, Su(var)306, Su(var)310, SuVar3-9, Suvar3-9, Suvar39, dSU(VAR)3-9, Su(Var)3-9, su(var)3-9, SUV39, SUV39H1, caa56376 Suvar39 Dm, Su-var(3)9, Su(var)3-902, Suvar(3)9, Su-var(3)902, Su(var) 3-9, Suv 3-9, CG6476, Su(var), Su(var)328, dSu(var)3-9, CG43664, Su(VAR)3-9" "IPR023779:Chromo domain, conserved site, IPR023780:Chromo domain, IPR000953:Chromo/chromo shadow domain, IPR001214:SET domain, IPR003616:Post-SET domain, IPR007728:Pre-SET domain, IPR011381:Histone H3-K9 methyltransferase, IPR016197:Chromo domain-like, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG43664 27-Aug-18 DroID_v2018_08 "Drer\suv39h1a, Drer\suv39h1b, Drer\ehmt1a, Drer\setmar, Drer\prss59.1, Drer\ehmt2, Drer\LOC103908930, Drer\prss59.2, Drer\ehmt1b, Drer\zmp:0000001088" "Scer\SET2, Scer\GCD11" "Cele\try-3, Cele\set-6, Cele\set-15, Cele\Y39G10AR.8, Cele\set-32, Cele\svh-1, Cele\try-1, Cele\set-33, Cele\set-21" "Xtro\ehmt1, Xtro\suv39h2, Xtro\ehmt2" "Mmus\Ovch2, Mmus\Suv39h1, Mmus\Ehmt2, Mmus\Ehmt1, Mmus\Tpsb2, Mmus\Setmar, Mmus\Suv39h2, Mmus\Eif2s3x" "Hsap\EHMT2, Hsap\EHMT1, Hsap\SUV39H1, Hsap\SUV39H2, Hsap\SETMAR, Hsap\PRSS48, Hsap\OVCH1, Hsap\OVCH2" "suppressor of variegation,dominant,non-suppressor of variegation,viable,enhancer of variegation,recessive,fertile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "cephalopharyngeal skeleton,maternal effect,syncytial blastoderm embryo,chromatin | maternal effect,dorsal bridge,oocyte nucleus,nurse cell & nucleus,follicle cell,ventral arm of pharyngeal sclerite,dorsal arm of pharyngeal sclerite,polytene chromosome chromocenter,polytene chromosome" FBgn0267765 asRNA:CR46096 - http://flybase.org/reports/FBgn0267765 non_protein_coding_gene - - - CR46096 - CR46096 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085573 CG41247 - http://flybase.org/reports/FBgn0085573 protein_coding_gene - - - CG41247 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037552 CG7800 - http://flybase.org/reports/FBgn0037552 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - "CT23295, CG7800" "IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like" CG7800 27-Aug-18 DroID_v2018_08 Drer\tlr8b - Cele\let-4 - Mmus\Tlr3 Hsap\TLR3 viable FBgn0035529 Fdx2 Ferredoxin 2 http://flybase.org/reports/FBgn0035529 protein_coding_gene "2 iron, 2 sulfur cluster binding ; GO:0051537 | inferred from electronic annotation with InterPro:IPR001055, InterPro:IPR018298 electron carrier activity ; GO:0009055 | inferred from sequence or structural similarity with UniProtKB:P10109" positive regulation of ecdysteroid biosynthetic process ; GO:0045998 | inferred from mutant phenotype pupariation ; GO:0035073 | inferred from mutant phenotype mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:P10109 "BcDNA:RH09920, BcDNA:RE08888, CG1319, Fdx2, Fdxh2" "IPR001041:2Fe-2S ferredoxin-type iron-sulfur binding domain, IPR001055:Adrenodoxin, IPR012675:Beta-grasp domain, IPR018298:Adrenodoxin, iron-sulphur binding site" CG1319 27-Aug-18 DroID_v2018_08 "Drer\fdx1b, Drer\fdx1, Drer\cox15, Drer\fdx1l" "Scer\COX15, Scer\YAH1" "Cele\cox-15, Cele\Y73F8A.27" "Xtro\fdx1, Xtro\fdx1l, Xtro\LOC100498263" "Mmus\Fdx1, Mmus\Fdx1l, Mmus\Cox15" "Hsap\FDX1L, Hsap\FDX1, Hsap\COX15" "viable,visible" trichogen cell FBgn0029830 Grip Glutamate receptor binding protein http://flybase.org/reports/FBgn0029830 protein_coding_gene guanylate kinase activity ; GO:0004385 | inferred from biological aspect of ancestor with PANTHER:PTN001501163 protein binding ; GO:0005515 | inferred from physical interaction with ed receptor binding ; GO:0005102 | inferred from physical interaction with fz2 ionotropic glutamate receptor binding ; GO:0035255 | inferred from biological aspect of ancestor with PANTHER:PTN001501163 protein binding ; GO:0005515 | inferred from physical interaction with kon "protein import into nucleus, translocation ; GO:0000060 | inferred from mutant phenotype synapse organization ; GO:0050808 | inferred from mutant phenotype determination of muscle attachment site ; GO:0016204 | inferred from mutant phenotype receptor localization to synapse ; GO:0097120 | inferred from biological aspect of ancestor with PANTHER:PTN001501163 chemical synaptic transmission ; GO:0007268 | inferred from biological aspect of ancestor with PANTHER:PTN001501163 nervous system development ; GO:0007399 | inferred from biological aspect of ancestor with PANTHER:PTN001501163 muscle organ morphogenesis ; GO:0048644 | inferred from mutant phenotype muscle attachment ; GO:0016203 | inferred from mutant phenotype inferred from genetic interaction with if inferred from genetic interaction with mew inferred from genetic interaction with kon receptor clustering ; GO:0043113 | inferred from biological aspect of ancestor with PANTHER:PTN001501163 establishment or maintenance of epithelial cell apical/basal polarity ; GO:0045197 | inferred from biological aspect of ancestor with PANTHER:PTN001501163" Golgi-associated vesicle ; GO:0005798 | inferred from direct assay terminal bouton ; GO:0043195 | inferred from direct assay postsynaptic density ; GO:0014069 | inferred from biological aspect of ancestor with PANTHER:PTN001501163 ionotropic glutamate receptor complex ; GO:0008328 | colocalizes_with inferred from biological aspect of ancestor with PANTHER:PTN001501163 basolateral plasma membrane ; GO:0016323 | inferred from biological aspect of ancestor with PANTHER:PTN001501163 neuromuscular junction ; GO:0031594 | inferred from direct assay postsynaptic membrane ; GO:0045211 | inferred from biological aspect of ancestor with PANTHER:PTN001501163 "DGrip, grip, CG14447, CG5980, dgrip, Grip, dGRIP, Dgrip, GRIP" IPR001478:PDZ domain CG14447 27-Aug-18 DroID_v2018_08 "Drer\grid2ipa, Drer\pard3bb, Drer\grip2a, Drer\dlg5a, Drer\ptpn21, Drer\slc9a3r1, Drer\il16, Drer\dlg1l, Drer\dlg4b, Drer\si:dkey-92i15.4, Drer\dlg1, Drer\ptpn13, Drer\grip1, Drer\lnx1, Drer\inadl, Drer\pdzd7b, Drer\frmpd2, Drer\grip2b" - "Cele\dlg-1, Cele\F23C8.13" "Xtro\grid2ip, Xtro\dlg5, Xtro\grip2, Xtro\lnx1, Xtro\ptpn13, Xtro\grip1, Xtro\ptpn14" "Mmus\Dlg5, Mmus\Dlg1, Mmus\Pdzd2, Mmus\Ush1c, Mmus\Grid2ip, Mmus\Grip2, Mmus\Patj, Mmus\Il16, Mmus\Lnx1, Mmus\Mpdz, Mmus\Dlg4, Mmus\Grasp, Mmus\Ptpn21, Mmus\Ptpn13, Mmus\Ptpn14, Mmus\Pdzd11, Mmus\Grip1, Mmus\Pdzph1" "Hsap\DLG5, Hsap\PDZD2, Hsap\MPDZ, Hsap\GRASP, Hsap\PATJ, Hsap\GRIP1, Hsap\IL16, Hsap\GRIP2, Hsap\DLG4, Hsap\GRID2IP, Hsap\PTPN21, Hsap\LNX1, Hsap\FRMPD2, Hsap\PARD3B, Hsap\PTPN13, Hsap\USH1C, Hsap\DLG1, Hsap\PTPN14" "wild-type,neuroanatomy defective,viable,lethal" "ventral longitudinal muscle,adult abdomen,adult head,A1-7 ventral longitudinal muscle 1,precursor,muscle system,embryonic/larval somatic muscle,embryonic somatic muscle,lateral transverse muscle,abdominal 1 dorsal oblique muscle 5,abdominal 2 dorsal oblique muscle 5,abdominal 3 dorsal oblique muscle 5,abdominal 4 dorsal oblique muscle 5,abdominal 5 dorsal oblique muscle 5,abdominal 6 dorsal oblique muscle 5,abdominal 7 dorsal oblique muscle 5,bouton,presynaptic active zoneC164" FBgn0053061 CG33061 - http://flybase.org/reports/FBgn0053061 protein_coding_gene calcium-activated potassium channel activity ; GO:0015269 | inferred from biological aspect of ancestor with PANTHER:PTN000278842 monovalent inorganic cation transport ; GO:0015672 | inferred from electronic annotation with InterPro:IPR007866 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR007866 "CG13057, CG33061" IPR007866:TRIC channel CG33061 27-Aug-18 DroID_v2018_08 "Drer\tmem38b, Drer\tmem38a" - "Cele\Y57A10A.28, Cele\Y57A10A.10" "Xtro\tmem38b, Xtro\tmem38a" "Mmus\Tmem38a, Mmus\Tmem38b" "Hsap\TMEM38B, Hsap\TMEM38A" FBgn0083258 E(smoDN)918 Enhancer of smoDN 918 http://flybase.org/reports/FBgn0083258 gene - - - E(smoDN)918 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085558 CG41027 - http://flybase.org/reports/FBgn0085558 protein_coding_gene - - - CG41027 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0058295 CG40295 - http://flybase.org/reports/FBgn0058295 protein_coding_gene - - - CG40295 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0053445 5SrRNA:CR33445 5SrRNA:CR33445 http://flybase.org/reports/FBgn0053445 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33445, 5SrRNA:CR33445" - CR33445 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031150 bves bves http://flybase.org/reports/FBgn0031150 protein_coding_gene - - membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR006916 "CG1754, CG15448, CG32513, BcDNA:SD21670, bves" "IPR006916:Popeye protein, IPR018490:Cyclic nucleotide-binding-like, IPR014710:RmlC-like jelly roll fold" CG32513 27-Aug-18 DroID_v2018_08 "Drer\popdc3, Drer\bves, Drer\popdc2" - - "Xtro\popdc2, Xtro\popdc3, Xtro\bves" "Mmus\Bves, Mmus\Popdc3, Mmus\Popdc2" "Hsap\POPDC3, Hsap\POPDC2, Hsap\BVES" "lethal - all die before end of embryonic stage,maternal effect,heat sensitive,some die during embryonic stage,hyperactive,conditional,chemical resistant,viable,fertile" FBgn0086081 snoRNA:Me28S-A30 - http://flybase.org/reports/FBgn0086081 snoRNA_gene - - - "snoRNA:Me28S-A30, Me28S-Am30, CR34710" - CR34710 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038827 Fancd2 Fancd2 http://flybase.org/reports/FBgn0038827 protein_coding_gene DNA polymerase binding ; GO:0070182 | inferred from biological aspect of ancestor with PANTHER:PTN000788426 intra-S DNA damage checkpoint ; GO:0031573 | inferred from mutant phenotype DNA repair ; GO:0006281 | inferred from mutant phenotype interstrand cross-link repair ; GO:0036297 | inferred from mutant phenotype interstrand cross-link repair ; GO:0036297 | inferred from mutant phenotype inferred from genetic interaction with spel1 nucleus ; GO:0005634 | inferred by curator from GO:0036297 condensed chromosome ; GO:0000793 | inferred from biological aspect of ancestor with PANTHER:PTN000788426 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000788426 "dmFANCD2, CG17269, CG31194, FANCD2, CG31192, Fancd2, FAD" "IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical, IPR029448:Fanconi anaemia protein FANCD2" CG17269 27-Aug-18 DroID_v2018_08 "Drer\fancd2, Drer\nup188, Drer\tex264a" - "Cele\C52E2.4, Cele\fcd-2" "Xtro\nup188, Xtro\fancd2" "Mmus\Fancd2, Mmus\Nup188" "Hsap\FANCD2, Hsap\NUP188" "visible,chemical conditional,tumorigenic,chemical sensitive,viable,mitotic cell cycle defective,conditional,lethal - all die before end of pupal stage,some die during pupal stage" "eye,chemical conditional,trichogen cell,mesothoracic tergum" FBgn0020868 anon-R258 anon-R258 http://flybase.org/reports/FBgn0020868 - gene - - - "2-R258, anon-R258" - - 27-Aug-18 DroID_v2018_08 - - - - - - "fertile,chemical sensitive,recessive" FBgn0000896 fs(1)M103 female sterile (1) M103 http://flybase.org/reports/FBgn0000896 - gene - - - fs(1)M103 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,maternal effect" FBgn0083088 hella hella http://flybase.org/reports/FBgn0083088 gene - - - hella - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001802 l(1)Mc24 lethal (1) Mc24 http://flybase.org/reports/FBgn0001802 - gene - - - l(1)Mc24 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0065407 l(2)SH1579 lethal (2) SH1579 http://flybase.org/reports/FBgn0065407 gene - - - "l(2)SH1579, l(2)SH2 1579" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0034282 Mapmodulin Mapmodulin http://flybase.org/reports/FBgn0034282 protein_coding_gene microtubule binding ; GO:0008017 | inferred from sequence or structural similarity nucleocytoplasmic transport ; GO:0006913 | inferred from sequence or structural similarity with UniProtKB:P39687 microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:P39687 nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:P39687 nucleoplasm ; GO:0005654 | inferred from direct assay perinuclear region of cytoplasm ; GO:0048471 | inferred from sequence or structural similarity with UniProtKB:P39687 endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with UniProtKB:P39687 "CT42180, CT18148, CG5784, anon-EST:fe3A2, Mapmodulin" "IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like" CG5784 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-267j14.7, Drer\anp32e, Drer\anp32a, Drer\nap1l4a, Drer\anp32b" - "Cele\F33H2.3, Cele\T19H12.2" "Xtro\anp32a, Xtro\anp32c, Xtro\anp32b, Xtro\anp32e" "Mmus\Shoc2, Mmus\Anp32b, Mmus\Anp32a, Mmus\Lrriq3, Mmus\Anp32e" "Hsap\LRRIQ3, Hsap\ANP32A, Hsap\ANP32C, Hsap\ANP32D, Hsap\ANP32E, Hsap\ANP32B, Hsap\SHOC2" viable embryonic/larval hemocyte | third instar larval stage FBgn0034201 CG17290 - http://flybase.org/reports/FBgn0034201 protein_coding_gene - - - "BcDNA:RE15976, CG17290" IPR004011:GYR motif CG17290 27-Aug-18 DroID_v2018_08 - - - - - - "viable,planar polarity defective,partially lethal - majority die,some die during pupal stage" FBgn0014156 e(y)7 enhancer of yellow 7 http://flybase.org/reports/FBgn0014156 - gene - - - e(y)7 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0050406 tRNA:Gly-TCC-2-2 transfer RNA:Glycine-TCC 2-2 http://flybase.org/reports/FBgn0050406 tRNA_gene GGA codon-amino acid adaptor activity ; GO:0033463 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033463 cytosol ; GO:0005829 | inferred by curator from GO:0033463 "AE002575.trna10-GlyTCC, tRNA[Gly][[GGA]], tRNA:gly:58AB, tRNA:G:58AB, tRNA:G:TCC:AE002575-a, CR30204, CR30406, chr2R.trna54-GlyTCC, tRNA-Gly-TCC-2-2, tRNA:Gly-TCC-2-2, tRNA:CR30406, GGA" - CR30406 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038834 RpS30 Ribosomal protein S30 http://flybase.org/reports/FBgn0038834 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR006846 structural constituent of ribosome ; GO:0003735 | traceable author statement translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR006846 cytoplasmic translation ; GO:0002181 | traceable author statement ribosome ; GO:0005840 | inferred from electronic annotation with InterPro:IPR006846 cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement "CG15697, S30, anon-EST:Posey127, RpS30, Rps30, Q9VDH8_DROME, RpS30a" "IPR006846:Ribosomal protein S30, IPR029071:Ubiquitin-related domain" CG15697 27-Aug-18 DroID_v2018_08 "Drer\faua, Drer\faub" "Scer\RPS30A, Scer\RPS30B" Cele\rps-30 Xtro\fau Mmus\Fau Hsap\FAU "lethal - all die before end of pupal stage,some die during pupal stage" DRSC26355 EK -0.6136451 -0.848712464 0.400387375 -3.487692823 2.538829726 4.223686726 FBgn0052580 Muc14A Mucin 14A http://flybase.org/reports/FBgn0052580 protein_coding_gene extracellular matrix structural constituent ; GO:0005201 | inferred from sequence model - extracellular matrix ; GO:0031012 | inferred from sequence model "Muc14A, CG32580" - CG32580 27-Aug-18 DroID_v2018_08 "Drer\asic2, Drer\scospondin, Drer\vwf, Drer\otogl, Drer\LOC799643" "Scer\MSB2, Scer\FLO9, Scer\FLO1, Scer\PRM7, Scer\FLO11, Scer\YMR317W, Scer\HPF1, Scer\YIL169C, Scer\HKR1, Scer\FIG2, Scer\FLO5" "Cele\H43E16.1, Cele\srap-1, Cele\ZC178.2, Cele\H02F09.3, Cele\clec-223, Cele\dpy-6" - "Mmus\Muc5ac, Mmus\Sspo, Mmus\Muc5b, Mmus\Muc2, Mmus\Vwf, Mmus\Akap13, Mmus\Muc6, Mmus\Muc4" "Hsap\MUC19, Hsap\SSPO, Hsap\MUC5B, Hsap\OTOG, Hsap\MUC16, Hsap\MUC4, Hsap\MUC2, Hsap\MUC17, Hsap\VWF, Hsap\MUC6" "viable,fertile" FBgn0025702 Srpk79D Serine-arginine protein kinase at 79D http://flybase.org/reports/FBgn0025702 "FBgn0037157, FBgn0037158" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 protein kinase activity ; GO:0004672 | inferred from direct assay protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000622883 protein kinase activity ; GO:0004672 | non-traceable author statement" intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN000622883 cytoskeletal matrix organization at active zone ; GO:0048789 | inferred from mutant phenotype defense response to bacterium ; GO:0042742 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from direct assay protein phosphorylation ; GO:0006468 | non-traceable author statement chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype regulation of mRNA processing ; GO:0050684 | inferred from biological aspect of ancestor with PANTHER:PTN000622883 spliceosomal complex assembly ; GO:0000245 | inferred from biological aspect of ancestor with PANTHER:PTN000622883 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000622075 presynaptic active zone ; GO:0048786 | colocalizes_with inferred from direct assay nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000622075 presynaptic active zone ; GO:0048786 | inferred from direct assay "SRPK, CG9085, BEST:CK01209, SRPK1, CK01209, atc, CG11489, Srpk79D, srpk79D" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG11489 27-Aug-18 DroID_v2018_08 "Drer\srpk1b, Drer\srpk2, Drer\srpk1a, Drer\srpk3, Drer\si:ch211-220i18.4" Scer\SKY1 Cele\spk-1 "Xtro\LOC100144966, Xtro\srpk2, Xtro\srpk1, Xtro\srpk3" "Mmus\Srpk3, Mmus\Srpk1, Mmus\Srpk2" "Hsap\SRPK1, Hsap\SRPK3, Hsap\SRPK2" "flight defective,recessive,locomotor behavior defective,short lived,neuroanatomy defective,viable,neurophysiology defective,fertile" "axon,neuron" FBgn0000812 fs(1)K93 female sterile (1) K93 http://flybase.org/reports/FBgn0000812 - gene - - - fs(1)K93 - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive" egg FBgn0263492 asRNA:CR43481 - http://flybase.org/reports/FBgn0263492 non_protein_coding_gene - - - CR43481 - CR43481 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0025751 l(3)93Dl lethal (3) 93Dl http://flybase.org/reports/FBgn0025751 - gene - - - "E23, l(3)93Dl" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0035711 CG8519 - http://flybase.org/reports/FBgn0035711 protein_coding_gene "GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR001806 GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR005225, InterPro:IPR020849" signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR020849 biological_process ; GO:0008150 | no biological data available membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR020849 cellular_component ; GO:0005575 | no biological data available CG8519 "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR020849:Small GTPase superfamily, Ras type" CG8519 27-Aug-18 DroID_v2018_08 "Drer\kras, Drer\hrasa, Drer\rsg1, Drer\rap2b, Drer\rerg, Drer\hrasb, Drer\rras2, Drer\gem, Drer\ralaa, Drer\zgc:171704, Drer\rasd1, Drer\rerglb, Drer\rap1aa, Drer\LOC100332969, Drer\rrad, Drer\rap2ab, Drer\diras1a, Drer\rheb, Drer\ralba, Drer\zgc:153845, Drer\diras2, Drer\zgc:64022, Drer\rasl11b, Drer\rasl11a, Drer\si:ch73-116o1.2, Drer\rem1, Drer\ralab, Drer\mras, Drer\zgc:110699, Drer\rasl10a, Drer\rem2, Drer\rap1ab, Drer\rhebl1, Drer\nras, Drer\ralbb, Drer\si:dkeyp-59c12.1, Drer\si:dkey-27j5.5, Drer\zgc:114118, Drer\zgc:152698, Drer\rit1, Drer\diras1b, Drer\rras, Drer\rasl12, Drer\rap2c, Drer\rergla" "Scer\RAS1, Scer\RHB1, Scer\RAS2, Scer\RSR1" Cele\Y71F9AR.2 "Xtro\rala, Xtro\gem, Xtro\rhebl1, Xtro\rasd1, Xtro\rasl10a, Xtro\diras3, Xtro\hras, Xtro\rerg, Xtro\rasd2, Xtro\rrad, Xtro\rap2c, Xtro\rit1, Xtro\rergl, Xtro\ralb, Xtro\diras2, Xtro\nras, Xtro\rem1, Xtro\LOC733456, Xtro\diras1, Xtro\rasl11a, Xtro\rap1b, Xtro\rasl11b, Xtro\rap2a, Xtro\rem2, Xtro\ras-dva, Xtro\rap1a, Xtro\rheb, Xtro\rsg1, Xtro\kras, Xtro\rap2b" "Mmus\Rasl11b, Mmus\Gm266, Mmus\Rit2, Mmus\Rasd2, Mmus\Rrad, Mmus\Diras2, Mmus\Rasl10a, Mmus\Rsg1, Mmus\Rasl11a, Mmus\Mras, Mmus\Rap2b, Mmus\Rasl10b, Mmus\Hras, Mmus\Rap2c, Mmus\Eras, Mmus\Rergl, Mmus\Rap1a, Mmus\Rras, Mmus\Gem, Mmus\Rhebl1, Mmus\Rit1, Mmus\Ralb, Mmus\Rem1, Mmus\Rerg, Mmus\Rheb, Mmus\Rap2a, Mmus\Rasd1, Mmus\Rem2, Mmus\Rras2, Mmus\Rala, Mmus\Nras, Mmus\Rap1b, Mmus\Rasl12, Mmus\Diras1, Mmus\Kras" "Hsap\RAP1A, Hsap\RASD2, Hsap\RRAS2, Hsap\RALA, Hsap\RHEBL1, Hsap\REM1, Hsap\RASD1, Hsap\RALB, Hsap\RHEB, Hsap\RAP2C, Hsap\RERG, Hsap\DIRAS1, Hsap\REM2, Hsap\RASL11A, Hsap\RIT1, Hsap\KRAS, Hsap\RERGL, Hsap\RAP2A, Hsap\NRAS, Hsap\RAP2B, Hsap\RIT2, Hsap\RAP1B, Hsap\DIRAS3, Hsap\RASL10B, Hsap\RASL10A, Hsap\MRAS, Hsap\RSG1, Hsap\GEM, Hsap\RASL12, Hsap\RRAS, Hsap\RRAD, Hsap\ERAS, Hsap\HRAS, Hsap\DIRAS2, Hsap\RASL11B" viable FBgn0005738 l(1)TK228 lethal (1) TK228 http://flybase.org/reports/FBgn0005738 - gene - - - "l228, l(1)TK228" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" "eye,lamina" FBgn0003992 vst vestar http://flybase.org/reports/FBgn0003992 - gene - - - vst - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,poor,female sterile" "wing,eye" FBgn0260329 GSd220 - http://flybase.org/reports/FBgn0260329 gene - - - GSd220 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,neuroanatomy defective" ventral nerve cord FBgn0003711 tipF temperature-induced paralytic F http://flybase.org/reports/FBgn0003711 - gene - - - tipF - - 27-Aug-18 DroID_v2018_08 - - - - - - "paralytic,heat sensitive" FBgn0003392 shi shibire http://flybase.org/reports/FBgn0003392 "FBgn0030705, FBgn0045942, FBgn0045943, FBgn0045944" protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR000375, InterPro:IPR001401, InterPro:IPR003130, InterPro:IPR030381 GTPase activity ; GO:0003924 | non-traceable author statement microtubule binding ; GO:0008017 | inferred from direct assay actin binding ; GO:0003779 | inferred from direct assay GTPase activity ; GO:0003924 | inferred from biological aspect of ancestor with PANTHER:PTN000170013" "memory=0007613 |...<> synaptic vesicle recycling=0036465 |...<> positive regulation of actin filament polymerization=0030838 |...<> epithelium development=0060429 |...<> chemical synaptic transmission=0007268 |...<> vesicle-mediated transport=0016192 | traceable author statement <> clathrin-dependent endocytosis=0072583 |...<> negative regulation of protein phosphorylation=0001933 |...<> synaptic vesicle endocytosis=0048488 | traceable author statement <> memory=0007613 | traceable author statement <> cortical actin cytoskeleton organization=0030866 |...<> endocytosis=0006897 |...<> receptor-mediated endocytosis=0006898 | <> protein localization to plasma membrane=0072659 |...<> synaptic vesicle transport=0048489 |... direct assay <> synaptic vesicle budding from presynaptic endocytic zone membrane=0016185 | traceable author statement <> germarium-derived egg chamber formation=0007293 |...<> mitotic cytokinesis=0000281 |...<> regulation of actin filament-based process=0032970 |... genetic interaction with jar <> regulation of synapse structure or activity=0050803 |...<> epithelial cell migration, open tracheal system=0007427 |...<> regulation of short-term neuronal synaptic plasticity=0048172 |...<> positive regulation of Notch signaling pathway=0045747 |...<> regulation of growth=0040008 |...<> mitochondrial fission=0000266 |... biological aspect of ancestor with PANTHER:PTN000902162 <> sperm individualization=0007291 |...<> dynamin family protein polymerization involved in mitochondrial fission=0003374 |... biological aspect of ancestor with PANTHER:PTN000170085 <> synaptic vesicle budding from presynaptic endocytic zone membrane=0016185 |...<> mitotic actomyosin contractile ring assembly=1903475 |...<> regulation of actin cytoskeleton organization=0032956 |... genetic interaction with jar <> endocytosis=0006897 | traceable author statement <> learning=0007612 |...<> open tracheal system development=0007424 |...<> membrane fusion=0061025 |... biological aspect of ancestor with PANTHER:PTN000170085 <> conditioned taste aversion=0001661 |...<> cellularization=0007349 |...<> sperm individualization=0007291 |... genetic interaction with jar <> endocytosis=0006897 |... direct assay <> compound eye retinal cell programmed cell death=0046667 |...<> cellularization=0007349 | traceable author statement <> synaptic vesicle endocytosis=0048488 |...<> extracellular matrix organization=0030198 |...<> short-term memory=0007614 |...<> membrane fission=0090148 |...<> dorsal appendage formation=0046843 |...<> regulation of tube architecture, open tracheal system=0035152 |...<> olfactory learning=0008355 |... direct assay <> border follicle cell migration=0007298 |...<> ovarian follicle cell development=0030707 |...<> syncytial blastoderm mitotic cell cycle=0035186 |...<> larval feeding behavior=0030536 |...<> response to heat=0009408 |...<> morphogenesis of a polarized epithelium=0001738 |...<> proboscis extension reflex=0007637 |...<> synaptic vesicle membrane organization=0048499 |...<> synaptic vesicle endocytosis=0048488 |... direct assay <> salivary gland morphogenesis=0007435 |...<> adherens junction maintenance=0034334 |... mutant phenotype" microtubule ; GO:0005874 | inferred from electronic annotation with InterPro:IPR027188 mitochondrial membrane ; GO:0031966 | inferred from biological aspect of ancestor with PANTHER:PTN000170085 plasma membrane ; GO:0005886 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay sperm individualization complex ; GO:0070864 | inferred from direct assay synapse ; GO:0045202 | inferred from mutant phenotype mitotic spindle ; GO:0072686 | inferred from direct assay presynaptic active zone membrane ; GO:0048787 | "shi, Dyn, Shi, CG18102, Ddyn4, Ddyn3, Ddyn, l(1)shi, l(1)VII, anon-WO0153538.14, anon-WO0153538.13, anon-WO0153538.12, DYN, dyn, dDyn, shibire, shibere, DNM3, dynamin, Shibire" "IPR000375:Dynamin central domain, IPR001401:Dynamin, GTPase domain, IPR001849:Pleckstrin homology domain, IPR003130:Dynamin GTPase effector, IPR011993:PH domain-like, IPR030381:Dynamin-type guanine nucleotide-binding (G) domain, IPR019762:Dynamin, GTPase region, conserved site, IPR020850:GTPase effector domain, IPR027188:Dynamin-2, IPR027741:Dynamin-1, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR022812:Dynamin superfamily" CG18102 27-Aug-18 DroID_v2018_08 "Drer\dnm1l, Drer\dnm1b, Drer\si:dkeyp-110c12.3, Drer\mxf, Drer\dnm2b, Drer\mxg, Drer\dnm2a, Drer\dnm1a, Drer\mxd, Drer\mxe, Drer\mxc, Drer\mxb, Drer\dnm3a, Drer\si:dkey-32e23.4" "Scer\VPS1, Scer\DNM1, Scer\MGM1" "Cele\drp-1, Cele\dyn-1" "Xtro\dnm2, Xtro\dnm1l, Xtro\dnm3, Xtro\dnm1" "Mmus\Dnm3, Mmus\Dnm1, Mmus\Dnm1l, Mmus\Dnm2" "Hsap\DNM1, Hsap\DNM2, Hsap\DNM1L, Hsap\DNM3, Hsap\MX1, Hsap\MX2" " larval stage , embryonic stage | late , adult stage && oogenesis stage , adult stage , spermatogenesis && adult stage , adult stage | male , embryonic stage | early , embryonic stage " " central nervous system

, ovary

, peripheral nervous system

, sense organ

, supraesophageal ganglion

, thoracico-abdominal ganglion

, subesophageal ganglion

, spermatogonium

, ventral nerve cord

, optic lobe

, adult head

, imaginal disc

, testis

, oocyte

, nurse cell

, antenno-maxillary complex

, spermatocyte

, male accessory gland

, retina

, adult brain

" "paralytic,heat sensitive,developmental rate defective,visible,somatic clone,phototaxis defective,locomotor behavior defective,smell perception defective,neuroanatomy defective,lethal,some die during immature adult stage,recessive,locomotor rhythm defective,neoplasia,neurophysiology defective,heat stress response defective,visual behavior defective,temperature conditional,endocytosis defective,lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type,uncoordinated,dominant,chemical resistant,feeding behavior defective,courtship behavior defective,song defective,mating defective,hypoactive,learning defective,memory defective,behavior defective,taste perception defective,male,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of first instar larval stage,some die during first instar larval stage,gravitaxis defective,optomotor response defective,circadian behavior defective,increased cell death,mating behavior defective,flight defective,chemical sensitive,touch sensitivity defective,touch perception defective,proboscis extension reflex defective,thermotaxis behavior defective,cell growth defective,increased cell size" "eye,somatic clone,eye disc,wing hair,supernumerary,heat sensitive,ensheathing neuropil associated glial cell,glial cell,synapse,embryonic ventral epidermis,embryonic epidermis,photoreceptor cell & synaptic vesicle,embryo,apical plasma membrane | heat sensitive,coated pit,synaptic vesicle | heat sensitive,synapse | heat sensitive,oocyte,endosome,retina,garland cell & endosome,mesothoracic tarsal bristle,presumptive embryonic/larval tracheal system,synaptic vesicle,somatic muscle,epidermis,microchaeta,syncytial blastoderm embryo,endosome | heat sensitive,mesothoracic metatarsus,primary pigment cell,secondary pigment cell,ectopic,wing vein L3,wing vein L4,wing vein L5,NMJ bouton,actin filament & spermatid | conditional ts,wing cell,adherens junction & wing cell | pupal stage | conditional - heat sensitive,mouthpart,rhabdomere,eye photoreceptor cell,dorsal trunk primordium,neuromuscular junction | heat sensitive,metatarsus,embryonic/larval neuromuscular junction,rhabdomere | heat sensitive,bouton,synapse | temperature conditional,embryonic/larval tracheal system,temperature conditional,embryonic/larval dorsal trunk,ommatidium,eye photoreceptor cell & ommatidium | ectopic,sensory mother cell,neuron,mesothoracic tergum & macrochaeta,wing & macrochaeta,macrochaeta,sensillum trichodeum of antennal segment 3,sensillum basiconicum of antennal segment 3,sensillum coeloconicum of antennal segment 3,trichogen cell,tormogen cell,macrochaeta & thorax | conditional ts,microchaeta & thorax | conditional ts,dorsal row,ventral row,abdominal 2 ventral longitudinal muscle & larval somatic muscle | conditional ts,larval somatic muscle & presynaptic membrane | conditional ts,larval somatic muscle & synaptic vesicle | conditional ts,presumptive embryonic salivary gland,photoreceptor cell,optic cartridge,wing,adult mushroom body,adult brain,neuromuscular junction | heat sensitiveMhc.PW,brain,glial cell & brain & pupa | conditional tsrepo,mushroom body,mushroom body vertical lobe,dorsal multidendritic neuron ddaC,adult fat body,giant fiber neuron,mushroom body dorsal paired medial cell,mesothoracic extracoxal depressor muscle 66,photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,rhabdomere R1,rhabdomere R2,rhabdomere R3,rhabdomere R4,rhabdomere R5,rhabdomere R6,medulla,lamina,axon & eye photoreceptor cell | conditional - heat sensitiveGMR.PF,dendrite | third instar larval stageGMR.PF,LNv neuron | third instar larval stage,dorsal appendage,dendritic arborizing neuron,dendrite | larval stage | heat sensitive109(2)80,class IV dendritic arborizing neuron,tertiary pigment cell,embryonic/larval glial cell,CSD interneuron,reticular neuropil associated glial cell,gamma Kenyon cell,synapsealrm.PD,multidendritic neuron,type II bouton,proboscis,air sac primordium,dorsal multidendritic neuron ddaC | pupal stage,border follicle cell,polar follicle cell,denticle belt,embryonic/first instar larval cuticle,denticle row 1,denticle row 2,denticle row 3,cuticle,ventral nerve cord commissure,abdominal ventral acute muscle 1 founder cell,abdominal ventral acute muscle 2 founder cell,abdominal ventral acute muscle 3 founder cell,wing disc,wing margin,wing margin bristle,fat body,imaginal disc,embryonic/larval neuroblast,embryonic myoblast,macrophage,embryonic/larval midgut | third instar larval stage,epithelium,female germline cyst" DRSC20373 EK 0.2744575 -1.427375881 1.648111937 -0.951967983 -1.245049712 -1.576499953 FBgn0034834 LS2 Large Subunit 2 http://flybase.org/reports/FBgn0034834 protein_coding_gene poly-pyrimidine tract binding ; GO:0008187 | inferred from biological aspect of ancestor with PANTHER:PTN000566979 pre-mRNA 3'-splice site binding ; GO:0030628 | inferred from biological aspect of ancestor with PANTHER:PTN000566979 protein binding ; GO:0005515 | inferred from physical interaction with U2af38 RNA binding ; GO:0003723 | inferred from mutant phenotype mRNA binding ; GO:0003729 | inferred from sequence or structural similarity mRNA processing ; GO:0006397 | inferred from electronic annotation with InterPro:IPR006529 negative regulation of RNA splicing ; GO:0033119 | inferred from mutant phenotype regulation of gene silencing ; GO:0060968 | inferred from mutant phenotype nuclear speck ; GO:0016607 | inferred from biological aspect of ancestor with PANTHER:PTN000566979 commitment complex ; GO:0000243 | inferred from biological aspect of ancestor with PANTHER:PTN000566979 U2AF ; GO:0089701 | inferred from biological aspect of ancestor with PANTHER:PTN000566979 U2-type prespliceosome ; GO:0071004 | inferred from biological aspect of ancestor with PANTHER:PTN000566979 "cg3162, CG3162, LS2" "IPR000504:RNA recognition motif domain, IPR006529:U2 snRNP auxilliary factor, large subunit, splicing factor, IPR003954:RNA recognition motif domain, eukaryote" CG3162 27-Aug-18 DroID_v2018_08 "Drer\uhmk1, Drer\u2af2a, Drer\u2af2b" "Scer\RNA15, Scer\MUD2" "Cele\uaf-1, Cele\Y82E9BR.2" Xtro\u2af2 "Mmus\U2af2, Mmus\Uhmk1" "Hsap\PPIE, Hsap\U2AF2, Hsap\UHMK1" "viable,lethal" DRSC04340 I -0.900722331 -1.838062114 -0.713948267 -0.004026071 0.348151905 -0.58474161 FBgn0030015 CG10761 - http://flybase.org/reports/FBgn0030015 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR011016 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:26025 protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with HGNC:26025 endoplasmic reticulum membrane ; GO:0005789 | inferred from sequence or structural similarity with HGNC:26025 mitochondrial outer membrane ; GO:0005741 | inferred from sequence or structural similarity with HGNC:26025 CG10761 "IPR011016:Zinc finger, RING-CH-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR033275:E3 ubiquitin-protein ligase MARCH-like" CG10761 27-Aug-18 DroID_v2018_08 "Drer\march6, Drer\march5l, Drer\march8, Drer\march5" Scer\SSM4 "Cele\marc-5, Cele\M110.3, Cele\marc-1, Cele\marc-6" "Xtro\march5, Xtro\march8" "Mmus\March5, Mmus\March1, Mmus\March8, Mmus\March10, Mmus\March6" "Hsap\MARCH8, Hsap\MARCH10, Hsap\MARCH6, Hsap\MARCH1, Hsap\MARCH5, Hsap\MARCH7" viable DRSC27665 K 0.045501567 0.431620401 0.162969916 0.612334621 0.171803971 1.882791523 FBgn0065162 l(3)SH040 lethal (3) SH040 http://flybase.org/reports/FBgn0065162 gene - - - "l(3)SH040, l(2)SH3 040" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0013813 Dhc98D Dynein heavy chain at 89D http://flybase.org/reports/FBgn0013813 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011704 ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity ATP-dependent microtubule motor activity, minus-end-directed ; GO:0008569 | inferred from sequence or structural similarity with UniProtKB:A8JDH8" microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity cilium movement ; GO:0003341 | inferred from sequence or structural similarity with UniProtKB:A8JDH8 microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity inner dynein arm ; GO:0036156 | inferred from sequence or structural similarity with UniProtKB:A8JDH8 "Dhc98D, CG1842, dhc, DHC, Dhc, DHC6" "IPR004273:Dynein heavy chain domain, IPR013594:Dynein heavy chain, domain-1, IPR013602:Dynein heavy chain, domain-2, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR024317:Dynein heavy chain, P-loop containing D4 domain, IPR024743:Dynein heavy chain, coiled coil stalk, IPR026982:Dynein-1-alpha heavy chain, flagellar inner arm I1 complex, IPR026983:Dynein heavy chain, IPR003593:AAA+ ATPase domain, IPR011704:ATPase, dynein-related, AAA domain" CG1842 27-Aug-18 DroID_v2018_08 "Drer\dnah2, Drer\dnah12, Drer\dnah7, Drer\dync1h1, Drer\dnah7l, Drer\dnah1, Drer\wu:fj30b09, Drer\si:dkeyp-86b9.1, Drer\dnah3, Drer\si:dkeyp-87a6.1, Drer\dnah9l" Scer\DYN1 Cele\che-3 "Xtro\dnah14, Xtro\dnah2, Xtro\dnah10, Xtro\dnah7" "Mmus\Dnhd1, Mmus\Dnah11, Mmus\Dnah9, Mmus\Dnah3, Mmus\Dnah5, Mmus\Dync2h1, Mmus\Dnah14, Mmus\Dnah7b, Mmus\Dnah1, Mmus\Dnah12, Mmus\Dync1h1, Mmus\Dnah2, Mmus\Dnah7a, Mmus\Dnah10, Mmus\Dnah17, Mmus\Dnah8, Mmus\Dnah6" "Hsap\DNAH8, Hsap\DNAH5, Hsap\DNAH9, Hsap\DNAH11, Hsap\DNAH1, Hsap\DNAH7, Hsap\DNAH2, Hsap\DNAH10, Hsap\CCDC88B, Hsap\DYNC1H1, Hsap\DNAH6, Hsap\DNAH14, Hsap\DNAH3, Hsap\DNHD1, Hsap\DNAH12, Hsap\DNAH17, Hsap\DYNC2H1" " adult stage | female , embryonic stage , adult stage | male " testis

FBgn0019736 l(1)98B lethal (1) 98B http://flybase.org/reports/FBgn0019736 - gene - - - l(1)98B - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0058413 CG40413 - http://flybase.org/reports/FBgn0058413 protein_coding_gene - - - CG40413 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031528 CG15412 - http://flybase.org/reports/FBgn0031528 protein_coding_gene - - - CG15412 "IPR032675:Leucine-rich repeat domain, L domain-like" CG15412 27-Aug-18 DroID_v2018_08 Drer\si:ch211-214j8.12 - - - - - viable FBgn0004421 gustA gustatory-defective A http://flybase.org/reports/FBgn0004421 "FBgn0001154, FBgn0001158" gene - - - "gust-A, gust[x2], gust[x1], gustA" - - 27-Aug-18 DroID_v2018_08 - - - - - - taste perception defective labellar taste bristle FBgn0083988 snoRNA:Me28S-C3420a snoRNA:Me28S-C3420a http://flybase.org/reports/FBgn0083988 snoRNA_gene - - - "CR34152, snoRNA:Me28S-C3420a, Me28S-C3420a" - CR34152 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267157 lncRNA:CR45597 - http://flybase.org/reports/FBgn0267157 non_protein_coding_gene - - - CR45597 - CR45597 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266766 lncRNA:CR45231 - http://flybase.org/reports/FBgn0266766 non_protein_coding_gene - - - CR45231 - CR45231 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263578 mir-4916 mir-4916 stem loop http://flybase.org/reports/FBgn0263578 miRNA_gene - - - "mir-4916, dme-mir-4916, CR43563" - CR43563 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036656 CG13026 - http://flybase.org/reports/FBgn0036656 protein_coding_gene - - - CG13026 - CG13026 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0039306 RIOK2 RIO kinase 2 http://flybase.org/reports/FBgn0039306 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR015285, InterPro:IPR018935 protein serine/threonine kinase activity ; GO:0004674 | inferred from electronic annotation with InterPro:IPR015285, InterPro:IPR018935 protein kinase activity ; GO:0004672 | inferred from sequence or structural similarity with SGD:S000005151" protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR015285 cellular response to starvation ; GO:0009267 | inferred from expression pattern neurogenesis ; GO:0022008 | inferred from mutant phenotype positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype positive regulation of peptide hormone secretion ; GO:0090277 | inferred from mutant phenotype positive regulation of glial cell proliferation ; GO:0060252 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000005151 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000005151 "CG11859, RIOK2, dRIOK2, Rio2" "IPR011009:Protein kinase-like domain, IPR018935:RIO kinase, conserved site, IPR015285:RIO2 kinase winged helix domain, N-terminal, IPR030484:Serine/threonine-protein kinase Rio2, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR000687:RIO kinase" CG11859 27-Aug-18 DroID_v2018_08 Drer\riok2 Scer\RIO2 Cele\riok-2 Xtro\riok2 Mmus\Riok2 Hsap\RIOK2 "lethal,neuroanatomy defective,partially lethal - majority die,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0086359 Invadolysin Invadolysin http://flybase.org/reports/FBgn0086359 protein_coding_gene metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR001577 peptidase activity ; GO:0008233 | inferred from direct assay cell adhesion ; GO:0007155 | inferred from electronic annotation with InterPro:IPR001577 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001577 regulation of choline O-acetyltransferase activity ; GO:1902769 | inferred from direct assay mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype lipid storage ; GO:0019915 | inferred from mutant phenotype imaginal disc development ; GO:0007444 | inferred from mutant phenotype brain development ; GO:0007420 | inferred from mutant phenotype positive regulation of mitotic metaphase/anaphase transition ; GO:0045842 | inferred from mutant phenotype electron transport chain ; GO:0022900 | inferred from direct assay mitotic chromosome condensation ; GO:0007076 | inferred from mutant phenotype chromatin remodeling ; GO:0006338 | inferred from mutant phenotype centrosome duplication ; GO:0051298 | inferred from mutant phenotype mitotic centrosome separation ; GO:0007100 | inferred from mutant phenotype gonad development ; GO:0008406 | inferred from mutant phenotype germ cell migration ; GO:0008354 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001577 cell leading edge ; GO:0031252 | inferred from sequence or structural similarity with UniProtKB:Q96KR4 cytoplasm ; GO:0005737 | inferred from direct assay "Invadolysin, invadolysin, DmIX-14, CG3953, IX-14, l(3)IX-14, l(3)SG34, inv" "IPR001577:Peptidase M8, leishmanolysin" CG3953 27-Aug-18 DroID_v2018_08 Drer\lmln - "Cele\Y43F4A.1, Cele\T13B5.9" - Mmus\Lmln Hsap\LMLN FBgn0085464 CG34435 - http://flybase.org/reports/FBgn0085464 protein_coding_gene "ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity" multicellular organism reproduction ; GO:0032504 | inferred from expression pattern myosin complex ; GO:0016459 | inferred from sequence or structural similarity extracellular space ; GO:0005615 | inferred from direct assay "CG34435, CG15780" IPR011992:EF-hand domain pair CG34435 27-Aug-18 DroID_v2018_08 "Drer\cmlc1, Drer\myl6, Drer\zgc:163073, Drer\mylz3, Drer\myl1, Drer\zgc:153867, Drer\myl4, Drer\myl13" Scer\MLC1 "Cele\mlc-7, Cele\mlc-6, Cele\cal-7, Cele\mlc-5" "Xtro\myl1, Xtro\myl4, Xtro\myl6, Xtro\myl3" "Mmus\Myl6b, Mmus\Myl4, Mmus\Myl3, Mmus\Myl6, Mmus\Myl1" "Hsap\MYL1, Hsap\MYL6B, Hsap\MYL3, Hsap\MYL6, Hsap\MYL4" FBgn0053986 CG33986 - http://flybase.org/reports/FBgn0053986 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "CG17014, CG7973, CG33986, FBgn0036507" IPR002557:Chitin binding domain CG33986 27-Aug-18 DroID_v2018_08 - - "Cele\R02F2.4, Cele\cbd-1, Cele\cpg-2, Cele\cpg-1, Cele\C39D10.7" - - - FBgn0260106 2L1668 - http://flybase.org/reports/FBgn0260106 gene - - - 2L1668 - - 27-Aug-18 DroID_v2018_08 - - - - - - "nucleus & terminal tracheal cell | somatic clone,embryonic/larval tracheal system,somatic clone" FBgn0004845 l(3)88Bc lethal (3) 88Bc http://flybase.org/reports/FBgn0004845 - gene - - - "l(3)M41, l(3)88Bc" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0266361 asRNA:CR45009 - http://flybase.org/reports/FBgn0266361 non_protein_coding_gene - - - CR45009 - CR45009 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0052676 stx stuxnet http://flybase.org/reports/FBgn0052676 protein_coding_gene - proteasomal ubiquitin-independent protein catabolic process ; GO:0010499 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay "CG9725, CG9732, CG32676, stx, stuxnet" "IPR000626:Ubiquitin domain, IPR029071:Ubiquitin-related domain" CG32676 27-Aug-18 DroID_v2018_08 "Drer\LOC100536600, Drer\midn" - - Xtro\midn Mmus\Midn Hsap\MIDN "viable,fertile,lethal,recessive,visible,lethal - all die before end of pupal stage,some die during pupal stage" "chaeta,supernumerary" FBgn0001593 l(1)carot10 lethal (1) carot10 http://flybase.org/reports/FBgn0001593 - gene - - - l(1)carot10 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0267519 28SrRNA-Psi:CR45859 28S ribosomal RNA pseudogene:CR45859 http://flybase.org/reports/FBgn0267519 pseudogene_attribute - - - "CR45859, 28SrRNA-Psi:CR45859" - CR45859 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0052058 Ir67c Ionotropic receptor 67c http://flybase.org/reports/FBgn0052058 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "Ir67c, DmelIR67c, CG32058, IR67c" - CG32058 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible,fertile" "chaeta,supernumerary,mesothoracic tergum" FBgn0004990 chr chrome http://flybase.org/reports/FBgn0004990 - gene - - - chr - - 27-Aug-18 DroID_v2018_08 - - - - - - "body color defective,recessive" FBgn0030014 CG15337 - http://flybase.org/reports/FBgn0030014 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15337 - CG15337 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0030433 mRpL49 mitochondrial ribosomal protein L49 http://flybase.org/reports/FBgn0030433 protein_coding_gene translation initiation factor activity ; GO:0003743 | inferred from electronic annotation with InterPro:IPR001950 structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:Q13405 translational initiation ; GO:0006413 | inferred from electronic annotation with InterPro:IPR001950 mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with UniProtKB:Q13405 mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement "MRP-L49, CG4647, BcDNA:RE35556, mRpL49, mRpl49" "IPR001950:SUI1 domain, IPR007740:Ribosomal protein L49/IMG2" CG4647 27-Aug-18 DroID_v2018_08 Drer\mrpl49 Scer\IMG2 Cele\mrpl-49 - Mmus\Mrpl49 Hsap\MRPL49 FBgn0085519 CG40798 - http://flybase.org/reports/FBgn0085519 protein_coding_gene - - - CG40798 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259562 B2015 - http://flybase.org/reports/FBgn0259562 gene - - - B2015 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "leg,tarsal segment" FBgn0000862 fs(1)M56 female sterile (1) M56 http://flybase.org/reports/FBgn0000862 - gene - - - fs(1)M56 - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive,lethal,rescuable maternal effect,lethal - all die before end of embryonic stage,heat sensitive,some die during embryonic stage" egg FBgn0016721 Reg-7 Rhythmically expressed gene 7 http://flybase.org/reports/FBgn0016721 - gene - - - "Dreg-7, Reg-7" - - 27-Aug-18 DroID_v2018_08 - - - - - - " embryonic stage | late , adult stage " adult head

FBgn0038806 CG5412 - http://flybase.org/reports/FBgn0038806 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG5412 "IPR005645:Serine hydrolase FSH, IPR029058:Alpha/Beta hydrolase fold" CG5412 27-Aug-18 DroID_v2018_08 Drer\ovca2 "Scer\FSH2, Scer\FSH3, Scer\FSH1, Scer\DFR1" "Cele\dhfr-1, Cele\C25G4.2" "Xtro\ovca2, Xtro\dhfr" "Mmus\Dhfr, Mmus\Ovca2" "Hsap\OVCA2, Hsap\DHFR" "visible,partially lethal - majority die,some die during pharate adult stage,lethal" "mesothoracic tergum,embryonic/larval brain" FBgn0024857 l(3)96Be lethal (3) 96Be http://flybase.org/reports/FBgn0024857 - gene - - - l(3)96Be - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0267647 lncRNA:CR45985 - http://flybase.org/reports/FBgn0267647 non_protein_coding_gene - - - CR45985 - CR45985 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005255 l(3)SG74 lethal (3) SG74 http://flybase.org/reports/FBgn0005255 - gene - - - l(3)SG74 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0030824 CG5070 - http://flybase.org/reports/FBgn0030824 protein_coding_gene - - - CG5070 - CG5070 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible" "trichogen cell,supernumerary" FBgn0266787 lncRNA:CR45252 - http://flybase.org/reports/FBgn0266787 non_protein_coding_gene - - - CR45252 - CR45252 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0083018 snoRNA:Psi18S-841b snoRNA:Psi18S-841b http://flybase.org/reports/FBgn0083018 snoRNA_gene - - - "snoRNA:Psi18S-841b, Psi18S-841b, psi18S-841b, CR34551, chr2R:16837876..16838002" - CR34551 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0014985 l(2)46Da lethal (2) 46Da http://flybase.org/reports/FBgn0014985 - gene - - - "VII, l(2)46Da" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0060815 l(3)S052904 lethal (3) S052904 http://flybase.org/reports/FBgn0060815 gene - - - "0529/04, l(3)S052904" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0038014 CG10041 - http://flybase.org/reports/FBgn0038014 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern proteolysis ; GO:0006508 | inferred from sequence model" extracellular space ; GO:0005615 | inferred from direct assay "SP178, CG10041" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site" CG10041 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-21e2.15, Drer\si:dkey-78l4.10, Drer\LOC558805, Drer\si:ch211-165b19.9, Drer\si:dkey-78l4.5, Drer\si:dkey-21e2.12, Drer\si:dkey-78l4.4, Drer\si:dkey-78l4.11" - "Cele\svh-1, Cele\try-3" - "Mmus\Gzmd, Mmus\Gzmm, Mmus\Gzmg, Mmus\Gzmn, Mmus\Prtn3, Mmus\Prss54, Mmus\Gzmf, Mmus\Mcpt4, Mmus\Ovch2, Mmus\2210010C04Rik, Mmus\Gzmb, Mmus\Gzme" "Hsap\GZMB, Hsap\OVCH1, Hsap\PRTN3, Hsap\ELANE, Hsap\ACR, Hsap\GZMM, Hsap\GZMH, Hsap\OVCH2" viable FBgn0019777 l(1)318 lethal (1) 318 http://flybase.org/reports/FBgn0019777 - gene - - - l(1)318 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,partially,recessive" FBgn0036545 GXIVsPLA2 GXIVsPLA2 http://flybase.org/reports/FBgn0036545 protein_coding_gene "phospholipase A2 activity ; GO:0004623 | inferred from electronic annotation with InterPro:IPR010711, InterPro:IPR013090 calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR010711" "lipid catabolic process ; GO:0016042 | inferred from electronic annotation with InterPro:IPR010711, InterPro:IPR013090 phospholipid metabolic process ; GO:0006644 | inferred from electronic annotation with InterPro:IPR016090 arachidonic acid secretion ; GO:0050482 | inferred from electronic annotation with InterPro:IPR016090" extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR010711 "CG17035, GXIVsPLA2, GXIVsPLA" "IPR010711:Group XII secretory phospholipase A2 precursor, IPR016090:Phospholipase A2 domain, IPR033113:Phospholipase A2, histidine active site" CG17035 27-Aug-18 DroID_v2018_08 "Drer\pla2g12a, Drer\pla2g12b" - "Cele\B0478.3, Cele\C31H1.5, Cele\F44B9.10" "Xtro\pla2g12a, Xtro\pla2g12b" "Mmus\Pla2g12a, Mmus\Pla2g12b" "Hsap\PLA2G12B, Hsap\PLA2G12A" "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0033369 CG8197 - http://flybase.org/reports/FBgn0033369 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype - CG8197 "IPR032675:Leucine-rich repeat domain, L domain-like, IPR001611:Leucine-rich repeat" CG8197 27-Aug-18 DroID_v2018_08 "Drer\nlrc3, Drer\lrrc45, Drer\nod1, Drer\tonsl, Drer\si:ch211-122c9.5, Drer\si:ch211-81a5.5, Drer\si:dkey-23k10.3, Drer\lrrc34, Drer\ciita, Drer\LOC101884653, Drer\nlrx1, Drer\cep78, Drer\nod2, Drer\nlrc3l" - - "Xtro\tonsl, Xtro\cep78, Xtro\lrrc45, Xtro\lrrc31, Xtro\lrrc34, Xtro\LOC100485518, Xtro\nod1, Xtro\nlrx1" "Mmus\Lrrc34, Mmus\Lrrc74b, Mmus\Nlrp4b, Mmus\Nlrp14, Mmus\Rnh1, Mmus\Nlrp4a, Mmus\Lrrc74a, Mmus\Nlrp9c, Mmus\Nlrp9b, Mmus\Lrrc71, Mmus\Nod2, Mmus\Nlrp9a, Mmus\Ciita, Mmus\Nlrp4f, Mmus\Lrrc45, Mmus\Cep78, Mmus\Nlrc3, Mmus\Tonsl, Mmus\Nod1, Mmus\Nlrx1, Mmus\Nlrp4c, Mmus\Nlrp4e, Mmus\Lrrc31" "Hsap\NLRP4, Hsap\NLRX1, Hsap\NOD2, Hsap\RNH1, Hsap\LRRC45, Hsap\CEP78, Hsap\TONSL, Hsap\NLRP9, Hsap\NLRP14, Hsap\LRRC71, Hsap\LRRC34, Hsap\CIITA, Hsap\NLRC5, Hsap\NOD1, Hsap\LRRC31, Hsap\LRRC74A" "viable,fertile,lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0051431 CG31431 - http://flybase.org/reports/FBgn0051431 protein_coding_gene - - - "CT32770, CG13414, CG31431" "IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR003598:Immunoglobulin subtype 2" CG31431 27-Aug-18 DroID_v2018_08 "Drer\fgfrl1b, Drer\fgfrl1a" - Cele\igcm-4 Xtro\fgfrl1 Mmus\Fgfrl1 Hsap\FGFRL1 "viable,partially lethal - majority die,some die during pupal stage" FBgn0264877 lncRNA:CR44068 - http://flybase.org/reports/FBgn0264877 non_protein_coding_gene - - - CR44068 - CR44068 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0041729 p400 p400 http://flybase.org/reports/FBgn0041729 gene protein binding ; GO:0005515 | inferred from physical interaction with z - brahma complex ; GO:0035060 | colocalizes_with inferred from direct assay p400 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0069216 gl(3R)70-22 gl(3R)70-22 http://flybase.org/reports/FBgn0069216 gene molecular_function ; GO:0003674 | no biological data available "anterior/posterior axis specification, embryo ; GO:0008595 | inferred from mutant phenotype" cellular_component ; GO:0005575 | no biological data available gl(3R)70-22 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage,maternal effect" "embryonic head,germline clone,maternal effect,cephalopharyngeal skeleton" FBgn0005205 l(3)DTS9 lethal (3) DTS9 http://flybase.org/reports/FBgn0005205 - gene - - - "DTS-9, l(3)DTS9" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,dominant,heat sensitive,female sterile" FBgn0040344 CG3711 - http://flybase.org/reports/FBgn0040344 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - "EG:BACR7A4.19, CG3711" "IPR000210:BTB/POZ domain, IPR006652:Kelch repeat type 1, IPR011333:SKP1/BTB/POZ domain, IPR015915:Kelch-type beta propeller" CG3711 27-Aug-18 DroID_v2018_08 "Drer\hcfc1a, Drer\klhdc4, Drer\lztr1, Drer\hcfc1b, Drer\rabepk" "Scer\KEL1, Scer\KEL2, Scer\KEL3" "Cele\F53E4.1, Cele\herc-1, Cele\Y50D7A.1, Cele\hcf-1" Xtro\lztr1 "Mmus\Rabepk, Mmus\Hcfc2, Mmus\Klhdc3, Mmus\Hcfc1, Mmus\Fbxo42, Mmus\Lztr1, Mmus\Klhdc9, Mmus\Klhdc4" "Hsap\KLHDC3, Hsap\LZTR1, Hsap\RABEPK, Hsap\KLHDC4, Hsap\HCFC2, Hsap\FBXO42, Hsap\KLHDC9, Hsap\HCFC1" viable DRSC26706 EK 0.897802722 0.651957744 1.770357193 0.076673707 0.492580824 1.514460153 FBgn0005105 gusD gustatory D http://flybase.org/reports/FBgn0005105 - gene molecular_function ; GO:0003674 | no biological data available larval feeding behavior ; GO:0030536 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available gusD - - 27-Aug-18 DroID_v2018_08 - - - - - - taste perception defective FBgn0060951 l(3)S036909 lethal (3) S036909 http://flybase.org/reports/FBgn0060951 gene - - - "369/9, 0369/09, l(3)S036909" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0263936 BG00004 - http://flybase.org/reports/FBgn0263936 gene - - - BG00004 - - 27-Aug-18 DroID_v2018_08 - - - - - - "long lived,male limited,starvation stress response defective,female limited,temperature response defective,gravitaxis defective" FBgn0037203 slif slimfast http://flybase.org/reports/FBgn0037203 protein_coding_gene basic amino acid transmembrane transporter activity ; GO:0015174 | inferred from direct assay amino acid transmembrane transport ; GO:0003333 | inferred from electronic annotation with InterPro:IPR002293 amino acid transport ; GO:0006865 | inferred from direct assay growth ; GO:0040007 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype lipid metabolic process ; GO:0006629 | inferred from mutant phenotype negative regulation of innate immune response ; GO:0045824 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002293 "Slif, CG11128, slif, slifA, slimfast" "IPR002293:Amino acid/polyamine transporter I, IPR029485:Cationic amino acid transporter, C-terminal" CG11128 27-Aug-18 DroID_v2018_08 "Drer\slc7a14a, Drer\slc7a1, Drer\slc7a3b, Drer\slc7a3a, Drer\slc7a14b, Drer\slc7a4, Drer\zgc:175280, Drer\zgc:63694, Drer\slc7a2" "Scer\MMP1, Scer\SAM3, Scer\CAN1, Scer\ALP1, Scer\AGP1, Scer\AGP2, Scer\HIP1, Scer\BAP3, Scer\AGP3, Scer\TAT2, Scer\SSY1, Scer\LYP1, Scer\UGA4, Scer\BAP2, Scer\DIP5, Scer\PUT4, Scer\GAP1, Scer\GNP1, Scer\TAT1" "Cele\F23F1.6, Cele\aat-5, Cele\B0454.6, Cele\Y53F4B.12, Cele\C50D2.2" "Xtro\slc7a4, Xtro\slc7a2.2, Xtro\slc7a1, Xtro\slc7a14, Xtro\slc7a2.1, Xtro\slc7a3" "Mmus\Slc7a4, Mmus\Slc7a14, Mmus\Slc7a1, Mmus\AU018091, Mmus\Slc7a3, Mmus\Slc7a2" "Hsap\SLC7A3, Hsap\SLC7A2, Hsap\SLC7A4, Hsap\SLC7A1, Hsap\SLC7A14" larval stage organism | ubiquitous "viable,fertile,decreased cell number,decreased cell size,lethal - all die before end of larval stage,partially,some die during larval stage,developmental rate defective,lethal,visible,increased cell number" "wing,posterior compartment,embryonic/larval fat body,larva,lipid droplet & larval oenocyteppl.PP,lipid droplet & larval fat bodyppl.PP,lipid droplet & larval oenocyteLsp2.PH,embryonic/larval neuroblast" FBgn0031580 CG15423 - http://flybase.org/reports/FBgn0031580 protein_coding_gene - - - CG15423 - CG15423 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0083253 E(smoDN)E Enhancer of smoDN group E http://flybase.org/reports/FBgn0083253 gene - smoothened signaling pathway ; GO:0007224 | inferred from genetic interaction with smo - "Group E, E(smoDN)E" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0024930 Su(var)2-b204 Su(var)2-b204 http://flybase.org/reports/FBgn0024930 - gene - - - "Su-var(2)b204, Su(var)2-b204" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0041738 l(2)k17019a lethal (2) k17019a http://flybase.org/reports/FBgn0041738 gene - - - l(2)k17019a - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0036796 CG18231 - http://flybase.org/reports/FBgn0036796 protein_coding_gene "L-ascorbic acid binding ; GO:0031418 | inferred from electronic annotation with InterPro:IPR006620 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen ; GO:0016702 | inferred from electronic annotation with InterPro:IPR013547 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR006620 procollagen-proline 4-dioxygenase activity ; GO:0004656 | inferred from electronic annotation with InterPro:IPR013547" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006620, InterPro:IPR013547" endoplasmic reticulum ; GO:0005783 | inferred from electronic annotation with InterPro:IPR013547 CG18231 "IPR013547:Prolyl 4-hydroxylase alpha-subunit, N-terminal, IPR006620:Prolyl 4-hydroxylase, alpha subunit, IPR011990:Tetratricopeptide-like helical domain" CG18231 27-Aug-18 DroID_v2018_08 "Drer\p4ha1b, Drer\p4ha2, Drer\p4htm, Drer\zgc:158254, Drer\p4ha1a, Drer\zgc:152670, Drer\p4ha3" - "Cele\Y43F8B.19, Cele\phy-4, Cele\phy-2, Cele\C14E2.4, Cele\phy-3" "Xtro\p4ha2, Xtro\p4ha3, Xtro\p4ha1" "Mmus\P4ha1, Mmus\P4ha2, Mmus\P4htm, Mmus\P4ha3" "Hsap\P4HA2, Hsap\P4HA3, Hsap\P4HA1, Hsap\P4HTM" "viable,fertile" FBgn0028687 Rpt1 Regulatory particle triple-A ATPase 1 http://flybase.org/reports/FBgn0028687 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959, InterPro:IPR003960 TBP-class protein binding ; GO:0017025 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 proteasome-activating ATPase activity ; GO:0036402 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 ATPase activity ; GO:0016887 | inferred from sequence model" positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ; GO:0045899 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred by curator from GO:0005838 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from mutant phenotype ER-associated ubiquitin-dependent protein catabolic process ; GO:0030433 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 "nuclear proteasome complex ; GO:0031595 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 proteasome regulatory particle ; GO:0005838 | inferred from direct assay proteasome regulatory particle, base subcomplex ; GO:0008540 | inferred from direct assay proteasome regulatory particle ; GO:0005838 | inferred from sequence or structural similarity with HGNC:9548 inferred from direct assay cytosolic proteasome complex ; GO:0031597 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 proteasome regulatory particle, base subcomplex ; GO:0008540 | inferred from sequence or structural similarity with SGD:S000001628 polytene chromosome ; GO:0005700 | inferred from direct assay" "p48B, dRpt1, Dm_Rpt1, l(2)43Ed, l(2)05643, Dmp48B, CG1341, anon-WO0118547.90, Rpt1, 1341, S7, Q7KMQ0_DROME" "IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR003960:ATPase, AAA-type, conserved site, IPR005937:26S proteasome subunit P45, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG1341 27-Aug-18 DroID_v2018_08 "Drer\wdr12, Drer\psmc6, Drer\psmc5, Drer\psmc2" Scer\RPT1 "Cele\rpt-6, Cele\rpt-4, Cele\rpt-1, Cele\F56F11.4" "Xtro\psmc5, Xtro\wdr12, Xtro\psmc6, Xtro\psmc2" "Mmus\Psmc6, Mmus\Psmc5, Mmus\Psmc2, Mmus\Wdr12" "Hsap\WDR12, Hsap\PSMC2, Hsap\PSMC5, Hsap\PSMC6" "lethal,recessive,neuroanatomy defective,lethal - all die during pupal stage" "intersegmental nerve,anterior fascicle & synapse" DRSC07542 IEK -3.340207102 -4.040886236 -2.245228358 -1.656881804 7.184191381 -1.702103651 FBgn0001704 l(1)ESHS25 lethal (1) ESHS25 http://flybase.org/reports/FBgn0001704 - gene - - - l(1)ESHS25 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0046696 RNaseP:RNA Ribonuclease P RNA http://flybase.org/reports/FBgn0046696 non_protein_coding_gene - - - "CR32868, RNaseP:RNA, RNase P RNA, P RNA, RNAseP, chr3R:27043287..27043402, RPR RNA" - CR32868 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0003599 Su(var)3-8 Suppressor of variegation 3-8 http://flybase.org/reports/FBgn0003599 - gene - - - "Su-var(3)8, Su(var)3-8" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,suppressor of variegation,dominant,heat sensitive,female sterile" FBgn0000795 fs(1)de6 female sterile (1) defective eggs 6 http://flybase.org/reports/FBgn0000795 - gene - - - "de6, fs(1)de6" - - 27-Aug-18 DroID_v2018_08 - - - - - - female sterile "dorsal appendage,chorion,endochorion" FBgn0050374 CR30374 - http://flybase.org/reports/FBgn0050374 pseudogene_attribute - - - "CR30374, CG30374" - CR30374 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260225 CR42499 - http://flybase.org/reports/FBgn0260225 pseudogene_attribute - - - "CR42499, CG42499" - CR42499 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038269 Rrp6 Rrp6 http://flybase.org/reports/FBgn0038269 protein_coding_gene "3'-5' exonuclease activity ; GO:0008408 | inferred from electronic annotation with InterPro:IPR002562 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR002121, InterPro:IPR002562, InterPro:IPR012337 nucleotide binding ; GO:0000166 | inferred from electronic annotation with InterPro:IPR010997" defense response to virus ; GO:0051607 | inferred from mutant phenotype nuclear RNA surveillance ; GO:0071027 | inferred from mutant phenotype mRNA polyadenylation ; GO:0006378 | inferred from mutant phenotype regulation of gene expression ; GO:0010468 | inferred from mutant phenotype nuclear exosome (RNase complex) ; GO:0000176 | inferred from sequence or structural similarity with SGD:S000005527 inferred from direct assay nuclear lamina ; GO:0005652 | inferred from direct assay nucleolus ; GO:0005730 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG7292, dRrp6, Rrp6, DmRrp6, rrp6, RRP6" "IPR002121:HRDC domain, IPR002562:3'-5' exonuclease domain, IPR012337:Ribonuclease H-like domain, IPR012588:Exosome-associated factor Rrp6, N-terminal, IPR010997:HRDC-like" CG7292 27-Aug-18 DroID_v2018_08 Drer\exosc10 Scer\RRP6 "Cele\egal-1, Cele\crn-3" Xtro\exosc10 Mmus\Exosc10 Hsap\EXOSC10 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" DRSC16223 IE 3.429577469 0.542280039 2.092372413 -3.305690023 -1.276981611 0.64242152 FBgn0013472 l(1)11P11 lethal (1) 11P11 http://flybase.org/reports/FBgn0013472 - gene - - - l(1)11P11 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" "ovariole,germline clone,egg" FBgn0036934 sNPF-R short neuropeptide F receptor http://flybase.org/reports/FBgn0036934 protein_coding_gene neuropeptide Y receptor activity ; GO:0004983 | inferred from electronic annotation with InterPro:IPR000611 neuropeptide receptor activity ; GO:0008188 | inferred from direct assay neuropeptide receptor activity ; GO:0008188 | inferred from sequence model short neuropeptide F receptor activity ; GO:0036400 | inferred from physical interaction with sNPF "G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR000611 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype positive regulation of feeding behavior ; GO:2000253 | inferred from mutant phenotype regulation of multicellular organism growth ; GO:0040014 | inferred from genetic interaction with mir-9a positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from mutant phenotype" integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model "CT22771, GPCR60, CG7395, Drm-sNPF-R, CG7395/CG18639, CG18639, anon-WO0131005.1, sNPF-R, sNPFR1, NPFR76F, Drm-NPFR76F, snpfr, sNPFR" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR000611:Neuropeptide Y receptor family, IPR017452:GPCR, rhodopsin-like, 7TM" CG7395 27-Aug-18 DroID_v2018_08 "Drer\prlhr2a, Drer\gpr88, Drer\npy4r, Drer\prlhr2b, Drer\npy2r, Drer\mchr1b, Drer\npy1r, Drer\npy8ar, Drer\si:dkey-202l22.3, Drer\cmklr1, Drer\prokr1b, Drer\npy2rl, Drer\si:dkey-27p18.2, Drer\npy7r, Drer\gpr19, Drer\npy8br, Drer\prlh2r, Drer\c5ar1, Drer\mchr1a, Drer\hcrtr2, Drer\prokr1a, Drer\si:ch73-160i9.3" - "Cele\npr-17, Cele\npr-7, Cele\npr-22, Cele\npr-3, Cele\npr-2, Cele\npr-10, Cele\npr-6, Cele\npr-5, Cele\npr-4, Cele\npr-1, Cele\npr-13" "Xtro\prlhr, Xtro\LOC100497124" "Mmus\Fpr3, Mmus\Npy6r, Mmus\Prokr1, Mmus\Npy4r, Mmus\Gpr19, Mmus\Npy2r, Mmus\Gpr83, Mmus\Fpr1, Mmus\Fpr-rs3, Mmus\Hcrtr2, Mmus\Mchr1, Mmus\Npy5r, Mmus\Prokr2, Mmus\Npbwr1, Mmus\Gpr88, Mmus\Fpr2, Mmus\C3ar1, Mmus\Npy1r, Mmus\C5ar1, Mmus\Prlhr" "Hsap\NPY5R, Hsap\FPR1, Hsap\OPRPN, Hsap\GPR88, Hsap\NPY2R, Hsap\PROKR2, Hsap\GPR32, Hsap\GPR33, Hsap\HCRTR2, Hsap\GPR19, Hsap\FPR2, Hsap\MCHR1, Hsap\GPR83, Hsap\NPY4R, Hsap\C3AR1, Hsap\PROKR1, Hsap\NPY1R, Hsap\PRLHR, Hsap\CHRM4" "large body,feeding behavior defective,small body,viable" FBgn0039329 CG10669 - http://flybase.org/reports/FBgn0039329 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG10669 "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type" CG10669 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-119o8.6, Drer\LOC100332930, Drer\znf1035, Drer\znf1032, Drer\si:dkeyp-68b7.7, Drer\znf1004, Drer\znf1014, Drer\znf1003, Drer\zgc:66448, Drer\znf1007, Drer\znf648, Drer\znf1005, Drer\si:dkey-253d23.2, Drer\znf1124, Drer\znf1023, Drer\znf989, Drer\znf1015, Drer\LOC100332443, Drer\si:ch211-266d19.4, Drer\znf1002, Drer\LOC100534814, Drer\znf1034, Drer\znf1001, Drer\si:ch211-261d7.6" - "Cele\zfp-2, Cele\che-1, Cele\Y55F3AM.14, Cele\Y48G8AL.10" Xtro\znf470 "Mmus\Zfp62, Mmus\Zfp628, Mmus\Gm13212, Mmus\Zfp40, Mmus\Zfp11, Mmus\2610008E11Rik, Mmus\Zfp729a, Mmus\Zfp473, Mmus\Zfp648, Mmus\Zfp945" "Hsap\ZFP62, Hsap\ZNF628, Hsap\ZNF845, Hsap\ZNF681, Hsap\ZNF485, Hsap\ZNF721, Hsap\ZNF808, Hsap\ZNF648, Hsap\ZNF226, Hsap\ZNF493" "viable,fertile" FBgn0262764 Mst77Y-15Psi Male-specific pseudogene 77Y 15 http://flybase.org/reports/FBgn0262764 pseudogene_attribute - - - Mst77Y-15Psi - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0025395 CG18838 - http://flybase.org/reports/FBgn0025395 FBgn0042161 protein_coding_gene - - - "EG:196F3.1, CG18838" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032167 CG5853 - http://flybase.org/reports/FBgn0032167 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR017871 sterol-transporting ATPase activity ; GO:0034041 | inferred from biological aspect of ancestor with PANTHER:PTN001059382 cholesterol transporter activity ; GO:0017127 | inferred from biological aspect of ancestor with PANTHER:PTN001059382" phagocytosis ; GO:0006909 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000443108 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000443108 CG5853 "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR013525:ABC-2 type transporter, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR017871:ABC transporter, conserved site" CG5853 27-Aug-18 DroID_v2018_08 "Drer\abcg4a, Drer\abcg4b, Drer\abcg8, Drer\abcg5, Drer\abcg2a, Drer\abcg2d, Drer\abcg2c, Drer\abcg1, Drer\abcg2b" "Scer\PDR5, Scer\YOL075C, Scer\PDR11, Scer\PDR15, Scer\PDR12, Scer\ADP1, Scer\AUS1, Scer\PDR10, Scer\SNQ2, Scer\PDR18" "Cele\wht-8, Cele\wht-2, Cele\wht-1, Cele\wht-7, Cele\abch-1, Cele\wht-6, Cele\wht-4, Cele\wht-5, Cele\wht-3" "Xtro\abcg5, Xtro\abcg8" "Mmus\Abcg1, Mmus\Abcg2, Mmus\Abcg8, Mmus\Abcg5, Mmus\Abcg3, Mmus\Abcg4" "Hsap\ABCG4, Hsap\ABCG5, Hsap\ABCG8, Hsap\ABCG2, Hsap\ABCG1" "viable,lethal" FBgn0035601 Uev1A Ubiquitin-conjugating enzyme variant 1A http://flybase.org/reports/FBgn0035601 protein_coding_gene ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 ubiquitin conjugating enzyme binding ; GO:0031624 | inferred from physical interaction with ben ubiquitin conjugating enzyme activity ; GO:0061631 | contributes_to inferred from direct assay protein polyubiquitination ; GO:0000209 | inferred from direct assay peptidoglycan recognition protein signaling pathway ; GO:0061057 | inferred from mutant phenotype protein K63-linked ubiquitination ; GO:0070534 | inferred from biological aspect of ancestor with PANTHER:PTN000629507 postreplication repair ; GO:0006301 | inferred from biological aspect of ancestor with PANTHER:PTN000629507 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000629507 UBC13-UEV1A complex ; GO:0035370 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 "dUEV1a, dUev1A, DmUEV, UEV, CG10640, Uev1A, UEV1A, uev1a, Uev1a, UEV1a, dUEV1A" "IPR000608:Ubiquitin-conjugating enzyme E2, IPR016135:Ubiquitin-conjugating enzyme/RWD-like" CG10640 27-Aug-18 DroID_v2018_08 "Drer\ube2v2, Drer\si:ch211-212o1.2, Drer\ube2v1, Drer\tmem189" Scer\MMS2 "Cele\uev-1, Cele\Y53C10A.5" "Xtro\ube2v2, Xtro\ube2v1, Xtro\tmem189" "Mmus\Tmem189, Mmus\Ube2v2, Mmus\Ube2v1" "Hsap\TMEM189, Hsap\TMEM189-UBE2V1, Hsap\UBE2V1, Hsap\UBE2V2" "lethal,lethal - all die before end of pupal stage,viable" FBgn0000698 fltD flight defective D http://flybase.org/reports/FBgn0000698 - gene - - - fltD - - 27-Aug-18 DroID_v2018_08 - - - - - - "flightless,jumping defective,partially" FBgn0040967 CG18666 - http://flybase.org/reports/FBgn0040967 protein_coding_gene protein phosphatase inhibitor activity ; GO:0004864 | inferred from electronic annotation with InterPro:IPR007062 molecular_function ; GO:0003674 | no biological data available regulation of phosphoprotein phosphatase activity ; GO:0043666 | inferred from electronic annotation with InterPro:IPR007062 regulation of signal transduction ; GO:0009966 | inferred from electronic annotation with InterPro:IPR007062 cellular_component ; GO:0005575 | no biological data available CG18666 IPR007062:Protein phosphatase inhibitor 2 (IPP-2) CG18666 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0016822 l(1)MZ1 lethal (1) MZ1 http://flybase.org/reports/FBgn0016822 - gene - - - "l(1)MZ1, M1" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0038674 CG14285 - http://flybase.org/reports/FBgn0038674 protein_coding_gene - - - CG14285 "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG14285 27-Aug-18 DroID_v2018_08 - - Cele\lin-23 - - - viable FBgn0001613 l(1)dd9 lethal (1) discs degenerate 9 http://flybase.org/reports/FBgn0001613 - gene - - - "d.deg.-9, l(1)d deg-9, l(1)d.deg.9, l(1)d.deg.-9, l(1)dd9" - - 27-Aug-18 DroID_v2018_08 - - - - - - "mitotic cell cycle defective,lethal - all die before end of larval stage,recessive,some die during larval stage" "imaginal disc,cell cycle" FBgn0003630 Su(var)323 Suppressor of variegation 323 http://flybase.org/reports/FBgn0003630 - gene - - - Su(var)323 - - 27-Aug-18 DroID_v2018_08 - - - - - - "suppressor of variegation,dominant,viable,non-suppressor of variegation" FBgn0022397 HelI Helicase I http://flybase.org/reports/FBgn0022397 - gene ATP-dependent DNA helicase activity ; GO:0004003 | inferred from direct assay - - "dhel I, HelI" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030620 CG5662 - http://flybase.org/reports/FBgn0030620 protein_coding_gene - protein targeting to mitochondrion ; GO:0006626 | inferred from sequence or structural similarity with UniProtKB:Q13505 mitochondrial outer membrane ; GO:0005741 | inferred from sequence or structural similarity with UniProtKB:Q13505 CG5662 "IPR033468:Metaxin, glutathione S-transferase domain, IPR019564:Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain" CG5662 27-Aug-18 DroID_v2018_08 "Drer\faxcb, Drer\mtx2, Drer\faxca" - "Cele\cdr-2, Cele\C25H3.7, Cele\cdr-4, Cele\mtx-2, Cele\hrg-2, Cele\Y48C3A.3, Cele\cdr-6" "Xtro\mtx2, Xtro\faxc" "Mmus\Faxc, Mmus\Mtx2" "Hsap\FAXC, Hsap\MTX2" viable DRSC19957 K 0.21012613 0.021352914 0.798962988 0.345411497 1.443347485 2.077063662 FBgn0031239 CG17075 - http://flybase.org/reports/FBgn0031239 protein_coding_gene protein-cysteine S-palmitoyltransferase activity ; GO:0019706 | inferred from sequence or structural similarity with SGD:S000004236 protein palmitoylation ; GO:0018345 | inferred from sequence or structural similarity with SGD:S000004236 endoplasmic reticulum ; GO:0005783 | inferred from direct assay CG17075 "IPR001594:Palmitoyltransferase, DHHC domain" CG17075 27-Aug-18 DroID_v2018_08 "Drer\zdhhc7, Drer\LOC100334198, Drer\zdhhc23b, Drer\zdhhc1, Drer\zdhhc24, Drer\zgc:77880, Drer\zdhhc9, Drer\zdhhc21, Drer\zdhhc12a, Drer\zdhhc5b, Drer\zdhhc3a, Drer\zdhhc22, Drer\zdhhc18a, Drer\zdhhc8b, Drer\zdhhc3b, Drer\zdhhc4, Drer\zdhhc12b, Drer\zdhhc14, Drer\zdhhc5a, Drer\zdhhc23a" "Scer\PFA5, Scer\ERF2, Scer\PFA4, Scer\SWF1" "Cele\dhhc-11, Cele\dhhc-8" "Xtro\zdhhc14, Xtro\zdhhc8, Xtro\zdhhc24, Xtro\zdhhc7, Xtro\zdhhc1, Xtro\zdhhc21, Xtro\zdhhc3, Xtro\zdhhc9, Xtro\zdhhc12, Xtro\dnz1" "Mmus\Zdhhc14, Mmus\Zdhhc4, Mmus\Zdhhc1, Mmus\Zdhhc12, Mmus\Zdhhc19, Mmus\Zdhhc22, Mmus\Zdhhc3, Mmus\Zdhhc24, Mmus\Zdhhc5, Mmus\Zdhhc21, Mmus\Zdhhc7, Mmus\Zdhhc8, Mmus\Zdhhc11, Mmus\Zdhhc23, Mmus\Zdhhc9, Mmus\Zdhhc18, Mmus\Zdhhc25" "Hsap\ZDHHC4, Hsap\ZDHHC18, Hsap\ZDHHC23, Hsap\ZDHHC11, Hsap\ZDHHC12, Hsap\ZDHHC21, Hsap\ZDHHC9, Hsap\ZDHHC24, Hsap\ZDHHC14, Hsap\ZDHHC8, Hsap\ZDHHC19, Hsap\ZDHHC7, Hsap\ZDHHC11B, Hsap\ZDHHC5, Hsap\ZDHHC22, Hsap\ZDHHC1, Hsap\ZDHHC3" viable DRSC00483 K -0.385386609 0.561626818 -0.131428872 -0.028656741 1.940463566 2.198337619 FBgn0263875 PL26 - http://flybase.org/reports/FBgn0263875 gene - - - PL26 - - 27-Aug-18 DroID_v2018_08 - - - - - - "embryonic/larval neuroblast,embryonic/larval brain" FBgn0015424 l(1)1CDa lethal (1) 1CDa http://flybase.org/reports/FBgn0015424 - gene - - - l(1)1CDa - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0083034 snoRNA:Psi18S-525e snoRNA:Psi18S-525e http://flybase.org/reports/FBgn0083034 snoRNA_gene - - - "snoRNA:Psi18S-525e, psi18S-525e, CR34577" - CR34577 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0050495 CG30495 - http://flybase.org/reports/FBgn0050495 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN000673029 - - "CG17986, CG30495" "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain" CG30495 27-Aug-18 DroID_v2018_08 "Drer\dhrs13a.2, Drer\dhrs13a.1, Drer\si:ch211-107o10.3, Drer\si:ch211-165b10.3, Drer\si:dkey-73n8.3, Drer\dhrsx, Drer\rdh14b, Drer\zgc:112332, Drer\rdh12, Drer\dhrs13l1, Drer\dhrs13a.3, Drer\zgc:153441, Drer\si:dkey-174n20.1, Drer\rdh12l, Drer\rdh14a, Drer\flj13639, Drer\dhrs12, Drer\ascc1, Drer\cbr1, Drer\cbr1l, Drer\si:dkey-23o4.6, Drer\si:dkey-94e7.2, Drer\zgc:64106" "Scer\GPI11, Scer\YNL181W, Scer\YKL107W, Scer\ENV9" "Cele\C27D8.4, Cele\dhs-22" "Xtro\rdh14, Xtro\dhrsx, Xtro\dhrs13, Xtro\rdh11, Xtro\dhrs12, Xtro\rdh13, Xtro\ascc1" "Mmus\Dhrsx, Mmus\1700003E16Rik, Mmus\Rdh12, Mmus\Cbr1, Mmus\Wwox, Mmus\Rdh13, Mmus\Rdh11, Mmus\Ascc1, Mmus\Cbr3, Mmus\Dhrs13, Mmus\Rdh14" "Hsap\RDH13, Hsap\C2orf81, Hsap\OSTC, Hsap\CBR3, Hsap\RDH14, Hsap\DHRS12, Hsap\DHRS13, Hsap\RDH12, Hsap\CBR1, Hsap\DHRSX, Hsap\RDH11" viable FBgn0037098 Wnk Wnk kinase http://flybase.org/reports/FBgn0037098 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR024678 protein serine/threonine kinase activity ; GO:0004674 | inferred from electronic annotation with InterPro:IPR024678 protein kinase activity ; GO:0004672 | NOT inferred from key residues protein kinase activity ; GO:0004672 | inferred from direct assay" axon guidance ; GO:0007411 | inferred from mutant phenotype positive regulation of canonical Wnt signaling pathway ; GO:0090263 | inferred from mutant phenotype inferred from genetic interaction with dsh inferred from genetic interaction with fz2 positive regulation of Wnt signaling pathway ; GO:0030177 | inferred from genetic interaction with fz inferred from genetic interaction with fz2 wing disc development ; GO:0035220 | inferred from mutant phenotype positive regulation of potassium ion import ; GO:1903288 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | NOT inferred from key residues protein autophosphorylation ; GO:0046777 | inferred from direct assay protein phosphorylation ; GO:0006468 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:14540 "WNK, wnk, CG7177, cg7177, Wnk, DWNK, dWNK" "IPR011009:Protein kinase-like domain, IPR008271:Serine/threonine-protein kinase, active site, IPR000719:Protein kinase domain, IPR024678:Serine/threonine-protein kinase OSR1/WNK, CCT domain" CG7177 27-Aug-18 DroID_v2018_08 "Drer\wnk4b, Drer\prkca, Drer\wnk2, Drer\wnk4a, Drer\wnk1a, Drer\wnk1b" - Cele\wnk-1 "Xtro\wnk3, Xtro\wnk1, Xtro\wnk4" "Mmus\Wnk3, Mmus\Wnk4, Mmus\Wnk2, Mmus\Wnk1" "Hsap\WNK1, Hsap\WNK3, Hsap\WNK2, Hsap\WNK4, Hsap\MAST2" "lethal,recessive,visible,somatic clone,neuroanatomy defective,viable,size defective" "wing vein,ectopic,somatic clone,microchaeta,macrochaeta,abdominal segment,wing margin,abdominal segment | pharate adult stage,embryonic/larval peripheral nervous system,trichogen cell,posterior wing margin,wing margin bristle,wing,posterior,wing vein L4" DRSC23372 IK -1.564982365 -1.893217094 -0.761355005 -0.650185289 -1.69331069 -0.940173761 FBgn0050502 fa2h fatty acid 2-hydroylase http://flybase.org/reports/FBgn0050502 protein_coding_gene heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR018506 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR006694 fatty acid alpha-hydroxylase activity ; GO:0080132 | inferred from biological aspect of ancestor with PANTHER:PTN000304948 fatty acid in-chain hydroxylase activity ; GO:0052722 | inferred from direct assay lipid biosynthetic process ; GO:0008610 | inferred from electronic annotation with InterPro:IPR006694 fatty acid metabolic process ; GO:0006631 | inferred from biological aspect of ancestor with PANTHER:PTN000304948 oxidation-reduction process ; GO:0055114 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR014430 endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000304948 "CG1645, CG1642, CG30502, fa2h, FA2H" "IPR001199:Cytochrome b5-like heme/steroid binding domain, IPR006694:Fatty acid hydroxylase, IPR018506:Cytochrome b5, heme-binding site, IPR014430:Sterol desaturase Scs7" CG30502 27-Aug-18 DroID_v2018_08 "Drer\cyb5a, Drer\fa2h" "Scer\SCS7, Scer\CYB5" "Cele\cytb-5.1, Cele\cytb-5.2, Cele\D2023.1, Cele\C25A1.5" Xtro\fa2h "Mmus\Cyb5a, Mmus\Fa2h, Mmus\Cyb5b" "Hsap\CYB5B, Hsap\FA2H, Hsap\CYB5A" "short lived,viable,fertile" FBgn0038007 Cyp313a3 Cyp313a3 http://flybase.org/reports/FBgn0038007 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "313a3, CG10093, Cyp313a3, CYP313a3" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG10093 27-Aug-18 DroID_v2018_08 "Drer\cyp4v7, Drer\zgc:123299, Drer\cyp26c1, Drer\cyp19a1a, Drer\cyp20a1, Drer\cyp46a1.1, Drer\cyp26a1, Drer\cyp46a1.3, Drer\cyp46a1.2, Drer\cyp4v8, Drer\cyp4t8, Drer\LOC100329425, Drer\cyp4f3, Drer\cyp26b1, Drer\cyp19a1b, Drer\cyp46a1.4" "Scer\DIT2, Scer\ERG11, Scer\ERG5" "Cele\cyp-29A3, Cele\cyp-29A4" "Xtro\cyp4v2, Xtro\cyp4b1, Xtro\cyp19a1, Xtro\mgc108213, Xtro\cyp4f22, Xtro\cyp20a1, Xtro\cyp4f2, Xtro\cyp26c1, Xtro\LOC100488227, Xtro\cyp4b1.2, Xtro\LOC100487918, Xtro\cyp26a1, Xtro\cyp26b1" "Mmus\Cyp4f18, Mmus\Cyp26a1, Mmus\Cyp4f16, Mmus\Cyp4a12a, Mmus\Cyp4b1, Mmus\Cyp4v3, Mmus\Cyp4a32, Mmus\Cyp4x1, Mmus\Cyp19a1, Mmus\Cyp4a10, Mmus\Cyp4f40, Mmus\Cyp4f17, Mmus\Cyp4f15, Mmus\Cyp4a14, Mmus\Cyp46a1, Mmus\Cyp4f37, Mmus\Cyp4f14, Mmus\Cyp4a31, Mmus\Cyp4a12b, Mmus\Cyp20a1, Mmus\Cyp26b1, Mmus\Cyp4f39, Mmus\Cyp4f13, Mmus\Cyp26c1" "Hsap\CYP4V2, Hsap\CYP4F12, Hsap\CYP4F2, Hsap\CYP4F3, Hsap\CYP4A11, Hsap\CYP4X1, Hsap\CYP26C1, Hsap\CYP26A1, Hsap\CYP19A1, Hsap\CYP26B1, Hsap\CYP46A1, Hsap\CYP4B1, Hsap\CYP20A1, Hsap\CYP4F22, Hsap\CYP4A22, Hsap\CYP4F11, Hsap\CYP4Z1" viable FBgn0043546 anon-AE002656.1 anon-AE002656.1 http://flybase.org/reports/FBgn0043546 gene - - - anon-AE002656.1 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0013596 l(3)B12-3-31 lethal (3) B12-3-31 http://flybase.org/reports/FBgn0013596 - gene - - - l(3)B12-3-31 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0266021 lncRNA:CR44786 - http://flybase.org/reports/FBgn0266021 non_protein_coding_gene - - - "CR44786, lincRNA.219" - CR44786 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0067053 R19 R19 http://flybase.org/reports/FBgn0067053 gene - - - R19 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,partially lethal - majority die" FBgn0060678 l(3)S077009b lethal (3) S077009b http://flybase.org/reports/FBgn0060678 gene - - - "0770/09, l(3)S077009b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0045485 Gr36c Gustatory receptor 36c http://flybase.org/reports/FBgn0045485 protein_coding_gene taste receptor activity ; GO:0008527 | non-traceable author statement olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of taste ; GO:0050909 | non-traceable author statement sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 integral component of membrane ; GO:0016021 | non-traceable author statement axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 "Gr36B.3, CG15137, Gr36B3, CG31748, Gr36c, GR36c" IPR013604:7TM chemoreceptor CG31748 27-Aug-18 DroID_v2018_08 - - "Cele\lite-1, Cele\gur-3" - - - viable FBgn0264084 lncRNA:CR43753 - http://flybase.org/reports/FBgn0264084 non_protein_coding_gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype - "CR43753, lincRNA.13" - CR43753 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266597 ewg::Dvir\ewg - http://flybase.org/reports/FBgn0266597 engineered_fusion_gene - - - ewg::Dvir\ewg - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265312 lncRNA:CR44285 - http://flybase.org/reports/FBgn0265312 non_protein_coding_gene - - - CR44285 - CR44285 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002389 l(3)93Df lethal (3) 93Df http://flybase.org/reports/FBgn0002389 - gene - - - "er19, l(3)er19, l(3)93Df" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,locomotor behavior defective" wing FBgn0037819 CG14688 - http://flybase.org/reports/FBgn0037819 protein_coding_gene phytanoyl-CoA dioxygenase activity ; GO:0048244 | inferred from sequence or structural similarity with HGNC:8940 fatty acid alpha-oxidation ; GO:0001561 | inferred from sequence or structural similarity with HGNC:8940 peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:8940 CG14688 IPR008775:Phytanoyl-CoA dioxygenase CG14688 27-Aug-18 DroID_v2018_08 Drer\phyhd1 - Cele\Y105C5B.9 "Xtro\phyhd1, Xtro\phyh" Mmus\Phyhd1 Hsap\PHYHD1 viable DRSC14911 I 1.715365879 1.487000648 0.35860784 0.592337658 -0.91082243 -0.422674427 FBgn0038978 tHMG1 testis-enriched HMG-box-containing protein 1 http://flybase.org/reports/FBgn0038978 protein_coding_gene protein homodimerization activity ; GO:0042803 | inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from direct assay - cytoplasm ; GO:0005737 | inferred from direct assay polytene chromosome interband ; GO:0005705 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG7045, tHMG1, tHMG-1, thmg-1" IPR009071:High mobility group box domain CG7045 27-Aug-18 DroID_v2018_08 "Drer\tfam, Drer\tox4a, Drer\tox4b, Drer\hmgb1a, Drer\hmgb3a, Drer\hmgb2a, Drer\tox3, Drer\ubtf, Drer\hmgb2b, Drer\hmg20b, Drer\hmgb3b, Drer\hmgb1b, Drer\ubtfl, Drer\tox, Drer\hmg20a" "Scer\POB3, Scer\NHP6A, Scer\ABF2, Scer\NHP6B, Scer\HMO1, Scer\IXR1, Scer\NHP10" "Cele\hmg-1.2, Cele\hmg-4, Cele\hmg-1.1" "Xtro\tox2, Xtro\tox, Xtro\tox4, Xtro\hmgb3, Xtro\tfam, Xtro\ubtf, Xtro\hmg20b, Xtro\tox3, Xtro\hmg20a, Xtro\hmgb2, Xtro\hmgb1" "Mmus\Tox2, Mmus\Ubtf, Mmus\Hmgb1, Mmus\Tox, Mmus\Hmgb3, Mmus\Hmg20b, Mmus\Hmg20a, Mmus\Tox3, Mmus\Tfam, Mmus\Ubtfl1, Mmus\Hmgb4, Mmus\Tox4, Mmus\Hmgb2" "Hsap\TOX2, Hsap\HMG20B, Hsap\TFAM, Hsap\HMGB4, Hsap\HMGB3, Hsap\HMG20A, Hsap\UBTF, Hsap\HMGB2, Hsap\TOX3, Hsap\TOX4, Hsap\HMGB1, Hsap\TOX" viable FBgn0266047 CG44812 - http://flybase.org/reports/FBgn0266047 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44812 - CG44812 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0011223 hall halley http://flybase.org/reports/FBgn0011223 - gene - spermatid development ; GO:0007286 | inferred from mutant phenotype - "hal, hall" - - 27-Aug-18 DroID_v2018_08 - - - - - - male sterile spermatid FBgn0031526 CG8838 - http://flybase.org/reports/FBgn0031526 protein_coding_gene - - - "anon-WO0140519.135, CG8838" - CG8838 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0030733 UQCR-14 Ubiquinol-cytochrome c reductase 14 kDa subunit http://flybase.org/reports/FBgn0030733 protein_coding_gene ubiquinol-cytochrome-c reductase activity ; GO:0008121 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000246311 ubiquinol-cytochrome-c reductase activity ; GO:0008121 | inferred from sequence or structural similarity with UniProtKB:P14927 "mitochondrial respiratory chain complex III assembly ; GO:0034551 | inferred from biological aspect of ancestor with PANTHER:PTN000246311 negative regulation of neuroblast proliferation ; GO:0007406 | inferred from mutant phenotype mitochondrial electron transport, ubiquinol to cytochrome c ; GO:0006122 | inferred from biological aspect of ancestor with PANTHER:PTN000246311 aerobic respiration ; GO:0009060 | inferred from biological aspect of ancestor with PANTHER:PTN000246311 mitochondrial electron transport, ubiquinol to cytochrome c ; GO:0006122 | inferred from sequence or structural similarity with UniProtKB:P14927 cellular respiration ; GO:0045333 | inferred from mutant phenotype" mitochondrial respiratory chain complex III ; GO:0005750 | inferred from sequence or structural similarity with UniProtKB:P14927 mitochondrial respiratory chain complex III ; GO:0005750 | inferred from biological aspect of ancestor with PANTHER:PTN000246311 "anon-EST:Posey167, BcDNA:RH44664, CG3560, Ucrh 14KDa, Ucrh, UCR6, UQCR-14" IPR003197:Cytochrome b-c1 complex subunit 7 CG3560 27-Aug-18 DroID_v2018_08 Drer\uqcrb Scer\QCR7 Cele\T02H6.11 Xtro\LOC101732809 Mmus\Uqcrb Hsap\UQCRB FBgn0001384 l(1)2Bp lethal (1) 2Bp http://flybase.org/reports/FBgn0001384 - gene - - - l(1)2Bp - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0044354 Quasimodo\env Quasimodo element env http://flybase.org/reports/FBgn0044354 transposable_element_gene - - - "cruiser\env, Quasimodo\env" "IPR012014:Retroelement-encoded protein, env-related, IPR022048:Envelope fusion protein-like" - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002517 l(3)Sp17 lethal (3) Sp17 http://flybase.org/reports/FBgn0002517 - gene - - - l(3)Sp17 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0041845 E(Sev-CycE)A14 E(Sev-CycE)A14 http://flybase.org/reports/FBgn0041845 gene - - - E(Sev-CycE)A14 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0052565 CR32565 - http://flybase.org/reports/FBgn0052565 non_protein_coding_gene - - - CR32565 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0022977 rrpD reduced receptor potential D http://flybase.org/reports/FBgn0022977 - gene - - - rrpD - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060414 l(3)S129717 lethal (3) S129717 http://flybase.org/reports/FBgn0060414 gene - - - "1297/17, l(3)S129717" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0039843 CG15567 - http://flybase.org/reports/FBgn0039843 protein_coding_gene - - - CG15567 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0013465 grdf grooming defective http://flybase.org/reports/FBgn0013465 - gene molecular_function ; GO:0003674 | no biological data available grooming behavior ; GO:0007625 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available grdf - - 27-Aug-18 DroID_v2018_08 - - - - - - "behavior defective,recessive" FBgn0011891 tRNA:Lys-CTT-1-1 transfer RNA:Lysine-CTT 1-1 http://flybase.org/reports/FBgn0011891 "FBgn0003795, FBgn0011886, FBgn0052837, FBgn0060185" tRNA_gene AAG codon-amino acid adaptor activity ; GO:0033444 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033444 cytosol ; GO:0005829 | inferred by curator from GO:0033444 "CR32837, tRNAlys, 35SLys, tRNA[Lys][[2]], AE002769.trna9-LysCTT, tRNA:K2, tRNA:K:CTT:AE002769-d, tRNA:lys2:42Ae, chr2R.trna100-LysCTT, tRNA-Lys-CTT-1-1, tRNA:Lys-CTT-1-1, tRNA:K2:42Ae, AAG" - CR32837 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266822 lncRNA:CR45284 - http://flybase.org/reports/FBgn0266822 non_protein_coding_gene - - - CR45284 - CR45284 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0016819 l(1)L6 lethal (1) L6 http://flybase.org/reports/FBgn0016819 - gene - - - "l(1)L6, L6" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0029817 CG15764 - http://flybase.org/reports/FBgn0029817 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT16792, CG15764" - CG15764 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0010796 l(3)03346 lethal (3) 03346 http://flybase.org/reports/FBgn0010796 - gene - - - "l(3)03347, l(3)03346" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0267419 CR45772 - http://flybase.org/reports/FBgn0267419 pseudogene_attribute - - - "CR45772, Mst77Y" - CR45772 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000227 Bsg25A Blastoderm-specific gene 25A http://flybase.org/reports/FBgn0000227 - protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from direct assay sequence-specific DNA binding ; GO:0043565 | contributes_to inferred from direct assay chromatin insulator sequence binding ; GO:0043035 | contributes_to inferred from direct assay chromatin insulator sequence binding ; GO:0043035 | inferred from direct assay embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from expression pattern positive regulation of chromatin silencing ; GO:0031937 | inferred from mutant phenotype chromatin silencing complex ; GO:0005677 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "bsg25A, clone 1.70, anon-EST:Liang-1.70, CG12205, Bsg25A, Elba1, Elba" IPR018379:BEN domain CG12205 27-Aug-18 DroID_v2018_08 - - - - - - " embryonic stage | syncytial blastoderm , embryonic stage | stage 4 " organism

viable FBgn0053431 5SrRNA:CR33431 5SrRNA:CR33431 http://flybase.org/reports/FBgn0053431 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33431, 5SrRNA:CR33431" - CR33431 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065035 AlkB AlkB http://flybase.org/reports/FBgn0065035 protein_coding_gene DNA-N1-methyladenine dioxygenase activity ; GO:0043734 | inferred from biological aspect of ancestor with PANTHER:PTN000421934 methylcytosine dioxygenase activity ; GO:0070579 | inferred from biological aspect of ancestor with PANTHER:PTN000421934 ferrous iron binding ; GO:0008198 | inferred from biological aspect of ancestor with PANTHER:PTN001819089 oxidative single-stranded DNA demethylation ; GO:0035552 | inferred from biological aspect of ancestor with PANTHER:PTN000421934 RNA repair ; GO:0042245 | inferred from biological aspect of ancestor with PANTHER:PTN000421934 DNA repair ; GO:0006281 | inferred from biological aspect of ancestor with PANTHER:PTN000421934 nuclear euchromatin ; GO:0005719 | inferred from biological aspect of ancestor with PANTHER:PTN000421874 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000421874 "CG33250, alkB, BEST:LD02396, AlkB" "IPR027450:Alpha-ketoglutarate-dependent dioxygenase AlkB-like, IPR004574:Alkylated DNA repair protein AlkB, IPR005123:Oxoglutarate/iron-dependent dioxygenase" CG33250 27-Aug-18 DroID_v2018_08 "Drer\alkbh1, Drer\atp6v1d" - Cele\Y51H7C.5 "Xtro\alkbh1, Xtro\atp6v1d" "Mmus\Nrp, Mmus\Alkbh1, Mmus\Atp6v1d" "Hsap\ALKBH1, Hsap\ATP6V1D" viable FBgn0061164 l(1)3At lethal (1) 3At http://flybase.org/reports/FBgn0061164 gene - - - l(1)3At - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0022299 l(1)M120.1 lethal (1) M120.1 http://flybase.org/reports/FBgn0022299 - gene - - - "M120.1, l(1)M120.1" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0067354 l(3)95EFb lethal (3) 95EFb http://flybase.org/reports/FBgn0067354 gene - - - l(3)95EFb - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" embryo FBgn0267960 lncRNA:CR46240 - http://flybase.org/reports/FBgn0267960 non_protein_coding_gene - - - "CR46240, lincRNA.507" - CR46240 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260115 2L4515 - http://flybase.org/reports/FBgn0260115 gene - - - 2L4515 - - 27-Aug-18 DroID_v2018_08 - - - - - - "terminal tracheal cell,somatic clone,embryonic/larval tracheal system" FBgn0016633 E(gl)3A Enhancer of glass 3A http://flybase.org/reports/FBgn0016633 - gene - - - E(gl)3A - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065833 l(2)SH0343 lethal (2) SH0343 http://flybase.org/reports/FBgn0065833 gene - - - "l(2)SH0343, l(2)SH2 0343" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0069100 mus325 mutagen-sensitive 325 http://flybase.org/reports/FBgn0069100 gene - - - mus325 - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,chemical sensitive" FBgn0035382 Or63a Odorant receptor 63a http://flybase.org/reports/FBgn0035382 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 "63a, DOR28, 63B.1, CG9969, Or63a" "IPR004117:Olfactory receptor, insect" CG9969 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0002609 E(spl)m3-HLH "Enhancer of split m3, helix-loop-helix" http://flybase.org/reports/FBgn0002609 FBgn0010046 protein_coding_gene "protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement sequence-specific DNA binding ; GO:0043565 | inferred from direct assay" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR003650 compound eye development ; GO:0048749 | traceable author statement regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype" - "CG8346, m3, E(spl)-m3, E(spl)m3, HLHM3, E(Spl)-HLH-m3, E(spl)M3, HLH-m3, E(spl)C, E(spl)C m3, HLHm3, bHLHc14, E(spl)m3-HLH" "IPR003650:Orange domain, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG8346 27-Aug-18 DroID_v2018_08 "Drer\her3, Drer\heyl, Drer\LOC100149863, Drer\her1, Drer\her8.2, Drer\hes6, Drer\her2, Drer\her15.1, Drer\her11, Drer\her6, Drer\bhlhe40, Drer\her4.4, Drer\her8a, Drer\hes2.2, Drer\her5, Drer\helt, Drer\hey1, Drer\bhlhe41, Drer\hey2, Drer\her7, Drer\her12, Drer\her15.2, Drer\her9, Drer\her4.2, Drer\her4.3, Drer\her13, Drer\hes2.1" Scer\PHO4 "Cele\hlh-27, Cele\hlh-25, Cele\lin-22" "Xtro\bhlhe40, Xtro\hes6.1, Xtro\bhlhe41, Xtro\hes2, Xtro\hes6.2, Xtro\hes1, Xtro\hes7.1, Xtro\hey2, Xtro\hey1, Xtro\hes4, Xtro\hes7.2" "Mmus\Bhlhe40, Mmus\Heyl, Mmus\Hes7, Mmus\Hes6, Mmus\Hes1, Mmus\Hes5, Mmus\Hes2, Mmus\Hey2, Mmus\Hes3, Mmus\Bhlhe41, Mmus\Helt, Mmus\Hey1" "Hsap\HES5, Hsap\HEYL, Hsap\HEY1, Hsap\HES3, Hsap\BHLHE41, Hsap\HES7, Hsap\HEY2, Hsap\HES4, Hsap\HES1, Hsap\BHLHE40, Hsap\HES2, Hsap\HES6, Hsap\HELT" " embryonic stage | stage 13 , embryonic stage | 6-14 hr , adult stage | female " " embryonic/larval midgut | restricted

, Malpighian tubule

" "visible,lethal - all die before end of pupal stage,some die during pupal stage" "scutum & microchaeta32B,scutum & microchaetaap-md544,scutum & macrochaetaap-md544,scutellar bristle,scutum & macrochaetah-1J3" FBgn0058347 CG40347 - http://flybase.org/reports/FBgn0058347 protein_coding_gene - - - CG40347 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0027298 l(1)G0137 lethal (1) G0137 http://flybase.org/reports/FBgn0027298 - gene - - - l(1)G0137 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0042207 CG18530 - http://flybase.org/reports/FBgn0042207 protein_coding_gene "hydrolase activity, acting on ester bonds ; GO:0016788 | inferred from electronic annotation with InterPro:IPR025483" lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR006693 - "CG12294, CG18530" "IPR025483:Lipase, eukaryotic, IPR006693:Partial AB-hydrolase lipase domain, IPR029058:Alpha/Beta hydrolase fold" CG18530 27-Aug-18 DroID_v2018_08 Drer\lipf "Scer\YEH1, Scer\YEH2, Scer\TGL1" "Cele\lipl-7, Cele\lipl-1, Cele\lipl-5, Cele\lipl-6, Cele\lipl-4, Cele\lipl-8, Cele\lipl-2, Cele\lipl-3" Xtro\lipa "Mmus\Lipf, Mmus\Lipn, Mmus\Lipk, Mmus\Lipm, Mmus\Lipo3, Mmus\Lipa, Mmus\Lipo2, Mmus\Lipo1, Mmus\Lipo4" "Hsap\LIPM, Hsap\LIPK, Hsap\LIPF, Hsap\LIPJ, Hsap\LIPN, Hsap\LIPA" viable DRSC15341 E 0.126313809 -0.815548406 3.197282764 -0.008054922 0.060502707 -0.525900322 FBgn0267649 pre-mod(mdg4)-H - http://flybase.org/reports/FBgn0267649 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "pre-mod(mdg4)-H, CG45987" "IPR007588:Zinc finger, FLYWCH-type" CG45987 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266762 CR45227 - http://flybase.org/reports/FBgn0266762 pseudogene_attribute - - - CR45227 - CR45227 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0050412 CG30412 - http://flybase.org/reports/FBgn0050412 protein_coding_gene ribosome binding ; GO:0043022 | inferred from biological aspect of ancestor with PANTHER:PTN000330676 mitochondrial respiratory chain complex III biogenesis ; GO:0097033 | inferred from biological aspect of ancestor with PANTHER:PTN000330676 inner mitochondrial membrane organization ; GO:0007007 | inferred from biological aspect of ancestor with PANTHER:PTN000330676 protein insertion into mitochondrial membrane from inner side ; GO:0032979 | inferred from biological aspect of ancestor with PANTHER:PTN000330676 mitochondrial respiratory chain complex IV biogenesis ; GO:0097034 | inferred from biological aspect of ancestor with PANTHER:PTN000330676 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000330676 "CG9803, anon-WO0140519.195, CG30412" - CG30412 27-Aug-18 DroID_v2018_08 Drer\zgc:123096 Scer\MBA1 Cele\Y62E10A.20 - Mmus\Maip1 Hsap\MAIP1 viable FBgn0030898 Andorra Andorra http://flybase.org/reports/FBgn0030898 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG12611, Andorra, and, andorra" - CG12611 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0025709 CNT2 Concentrative nucleoside transporter 2 http://flybase.org/reports/FBgn0025709 FBgn0033370 protein_coding_gene nucleoside:sodium symporter activity ; GO:0005415 | inferred from biological aspect of ancestor with PANTHER:PTN000834192 "nucleoside transmembrane transport ; GO:1901642 | inferred from electronic annotation with InterPro:IPR008276, InterPro:IPR018270" integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000063482 "BEST:CK00459, CK00459, DmCnt2, CNT2, CG8083" "IPR002668:Concentrative nucleoside transporter N-terminal domain, IPR008276:Concentrative nucleoside transporter, IPR011642:Nucleoside transporter/FeoB GTPase, Gate domain, IPR011657:Concentrative nucleoside transporter C-terminal domain, IPR018270:Concentrative nucleoside transporter, metazoan/bacterial" CG8083 27-Aug-18 DroID_v2018_08 Drer\slc28a1 - "Cele\slc-28.1, Cele\slc-28.2" "Xtro\slc28a2, Xtro\slc28a3" "Mmus\Gm14085, Mmus\Slc28a1, Mmus\Slc28a3, Mmus\Slc28a2" "Hsap\SLC28A2, Hsap\SLC28A1, Hsap\SLC28A3" "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" DRSC07073 I 1.553097522 0.944152137 1.099184242 0.507491467 -0.255345893 -0.239562501 FBgn0065485 l(2)SH1263 lethal (2) SH1263 http://flybase.org/reports/FBgn0065485 gene - - - "l(2)SH1263, l(2)SH2 1263" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0034312 CG10916 - http://flybase.org/reports/FBgn0034312 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with MGI:MGI:1096377 protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with MGI:MGI:1096377 determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype intracellular signal transduction ; GO:0035556 | inferred from sequence or structural similarity with MGI:MGI:1096377 cellular_component ; GO:0005575 | no biological data available CG10916 "IPR001841:Zinc finger, RING-type, IPR006616:DM9 repeat, IPR024518:Domain of unknown function DUF3421, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG10916 27-Aug-18 DroID_v2018_08 "Drer\rnf2, Drer\lnx1, Drer\traip, Drer\si:ch211-207l14.1, Drer\lnx2b" - "Cele\spat-3, Cele\B0432.13, Cele\ZK637.14" "Xtro\traip, Xtro\rnf2" "Mmus\Traip, Mmus\Brca1, Mmus\Ring1, Mmus\Rnf2" "Hsap\BRCA1, Hsap\RNF2, Hsap\RING1, Hsap\PCGF1" "viable,fertile,long lived" FBgn0083289 E(smoDN)2047 Enhancer of smoDN 2047 http://flybase.org/reports/FBgn0083289 gene - - - E(smoDN)2047 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0017385 l(1)15Eb lethal (1) 15Eb http://flybase.org/reports/FBgn0017385 - gene - - - l(1)15Eb - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0259730 tal-1A tarsal-less 1A http://flybase.org/reports/FBgn0259730 protein_coding_gene molecular_function ; GO:0003674 | no biological data available actin filament organization ; GO:0007015 | inferred from genetic interaction with tal morphogenesis of an epithelium ; GO:0002009 | inferred from genetic interaction with tal imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "Dm1, tal-1A, CG42384, Pep1, ORF1, tal, ORF 1A, pri, Tal1A, Pri" - CG42384 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264493 rdx roadkill http://flybase.org/reports/FBgn0264493 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P19538 inferred from physical interaction with UniProtKB:Q9V475 ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 protein homodimerization activity ; GO:0042803 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with ci eye morphogenesis ; GO:0048592 | inferred from mutant phenotype negative regulation of smoothened signaling pathway ; GO:0045879 | inferred from mutant phenotype negative regulation of protein import into nucleus ; GO:0042308 | inferred from mutant phenotype protein ubiquitination ; GO:0016567 | inferred from mutant phenotype positive regulation of apoptotic process ; GO:0043065 | inferred from genetic interaction with egr protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 segment polarity determination ; GO:0007367 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype establishment of ommatidial planar polarity ; GO:0042067 | inferred from mutant phenotype positive regulation of JNK cascade ; GO:0046330 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 eye development ; GO:0001654 | inferred from mutant phenotype protein destabilization ; GO:0031648 | inferred from mutant phenotype regulation of proteolysis ; GO:0030162 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay SCF ubiquitin ligase complex ; GO:0019005 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 "rdx, CG9924, Rdx, SPOP, hib, HIB, mei-P19, l(3)03477, l(3)2004, l(3)88Aa, l(3)A6, l(3)SG40, l(3)dsl6, l(3)j1D1, l(3)j4C7, l(3)dsl-6, CG12537, Dromel_CG9924_FBtr0082871_rdx_mORF, D-SPOP, Spop, anon-WO0118547.577, BEST:GM07940, CG10235, 0869/09, l(3)S086909, Hib" "IPR034089:SPOP, C-terminal BACK-like domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR000210:BTB/POZ domain, IPR002083:MATH/TRAF domain, IPR008974:TRAF-like, IPR011333:SKP1/BTB/POZ domain" CG12537 27-Aug-18 DroID_v2018_08 "Drer\spopla, Drer\spoplb, Drer\spop, Drer\klhl11, Drer\kbtbd4" Scer\YIL001W "Cele\bath-42, Cele\math-25, Cele\bath-43, Cele\btb-5, Cele\btb-14, Cele\btb-13, Cele\btb-7, Cele\math-21, Cele\R10E4.1, Cele\math-50, Cele\btb-20, Cele\hpo-9, Cele\math-10, Cele\btb-6, Cele\Y59E9AL.8, Cele\mel-26, Cele\btb-17, Cele\btb-16, Cele\bath-30, Cele\btb-18, Cele\bath-40, Cele\btb-19, Cele\btb-11, Cele\btb-12, Cele\btb-9" Xtro\spop "Mmus\Tdpoz1, Mmus\Klhl11, Mmus\Tdpoz2, Mmus\Tdpoz5, Mmus\Tdpoz4, Mmus\Kbtbd4, Mmus\Gm10696, Mmus\Gm10697, Mmus\Gm4858, Mmus\Gm9125, Mmus\Spop, Mmus\Spopl, Mmus\Tdpoz3" "Hsap\SPOPL, Hsap\KLHL11, Hsap\SPOP, Hsap\KBTBD4" DRSC16580 I 1.855874998 -0.122935647 0.146086333 0.250765959 -0.58438681 -0.203533946 FBgn0039988 CG12555 - http://flybase.org/reports/FBgn0039988 protein_coding_gene - - - CG12555 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039896 yellow-h yellow-h http://flybase.org/reports/FBgn0039896 protein_coding_gene - melanin biosynthetic process ; GO:0042438 | inferred from biological aspect of ancestor with PANTHER:PTN000000448 cuticle pigmentation ; GO:0048067 | inferred from biological aspect of ancestor with PANTHER:PTN000000448 - "CG1629, yellow-h, yell-h, h" "IPR017996:Major royal jelly protein/protein yellow, IPR011042:Six-bladed beta-propeller, TolB-like" CG1629 27-Aug-18 DroID_v2018_08 Drer\dpm3 - "Cele\T27A1.3, Cele\F49E11.8, Cele\fbxa-76, Cele\C24H12.1" Xtro\dpm3 Mmus\Dpm3 Hsap\DPM3 viable FBgn0029713 CG11436 - http://flybase.org/reports/FBgn0029713 protein_coding_gene molecular_function ; GO:0003674 | no biological data available actin filament polymerization ; GO:0030041 | inferred from biological aspect of ancestor with PANTHER:PTN001043092 actin cytoskeleton ; GO:0015629 | inferred from biological aspect of ancestor with PANTHER:PTN001043092 CG11436 "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat" CG11436 27-Aug-18 DroID_v2018_08 Drer\ttc17 - Cele\T19A5.1 Xtro\ttc17 Mmus\Ttc17 Hsap\TTC17 FBgn0051690 CG31690 - http://flybase.org/reports/FBgn0051690 protein_coding_gene - biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG15397, CG11542, CG31690" "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR013618:Domain of unknown function DUF1736, IPR019734:Tetratricopeptide repeat, IPR001440:Tetratricopeptide repeat 1" CG31690 27-Aug-18 DroID_v2018_08 "Drer\ttc25, Drer\kdm6ba, Drer\kdm6a, Drer\ifit9, Drer\ogt.2, Drer\bbs4, Drer\spag1b, Drer\spag1a, Drer\ifit15, Drer\ifit8, Drer\dyx1c1, Drer\ifit14, Drer\tmtc2b, Drer\ifit16, Drer\tomm34, Drer\ogt.1, Drer\tmtc2a, Drer\fkbpl, Drer\kdm6al, Drer\ttc6, Drer\tmtc3" "Scer\SWA2, Scer\TAH1, Scer\CYC8" Cele\F32D1.3 "Xtro\tmtc2, Xtro\tmtc3, Xtro\ifit5, Xtro\kdm6b, Xtro\ttc16, Xtro\bbs4, Xtro\ttc25, Xtro\spag1, Xtro\ogt, Xtro\kdm6a, Xtro\dyx1c1" "Mmus\Fkbpl, Mmus\Spag1, Mmus\Bbs4, Mmus\Ttc25, Mmus\Kdm6b, Mmus\Ifit1, Mmus\Ifit3b, Mmus\Tmtc2, Mmus\Dyx1c1, Mmus\Lonrf3, Mmus\Ifit1bl2, Mmus\Tmtc1, Mmus\Ifit3, Mmus\Ttc16, Mmus\Ogt, Mmus\Kdm6a, Mmus\Uty, Mmus\Tmtc3, Mmus\Tomm34, Mmus\Ifit1bl1, Mmus\Ttc24, Mmus\Ifit2" "Hsap\TMTC2, Hsap\BBS4, Hsap\TMTC1, Hsap\KDM6A, Hsap\UTY, Hsap\LONRF3, Hsap\IFIT1, Hsap\IFIT5, Hsap\TMTC3, Hsap\TTC32, Hsap\TTC6, Hsap\IFIT1B, Hsap\KDM6B, Hsap\TTC24, Hsap\OGT, Hsap\SPAG1, Hsap\DYX1C1, Hsap\TOMM34, Hsap\IFIT2, Hsap\IFIT3, Hsap\FKBPL, Hsap\TTC16, Hsap\LONRF2" "viable,fertile" FBgn0259565 B2019 - http://flybase.org/reports/FBgn0259565 gene - - - B2019 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible wing FBgn0065586 l(2)SH0911 lethal (2) SH0911 http://flybase.org/reports/FBgn0065586 gene - - - "l(2)SH0911, l(2)SH2 0911" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0262618 Dif::Rel Dif::Rel http://flybase.org/reports/FBgn0262618 engineered_fusion_gene - - - "Dif::Rel, Dif^Rel" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030593 CG9512 - http://flybase.org/reports/FBgn0030593 protein_coding_gene "oxidoreductase activity, acting on CH-OH group of donors ; GO:0016614 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR007867, InterPro:IPR012132 flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR012132 oxidoreductase activity ; GO:0016491 | inferred from sequence or structural similarity with Eo" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR007867, InterPro:IPR012132, InterPro:IPR023753 ecdysteroid metabolic process ; GO:0045455 | inferred from sequence or structural similarity with Eo inferred from genomic context with Eo" - "CT26924, CG9512, Dmel_CG9512" "IPR000172:Glucose-methanol-choline oxidoreductase, N-terminal, IPR007867:Glucose-methanol-choline oxidoreductase, C-terminal, IPR012132:Glucose-methanol-choline oxidoreductase, IPR023753:FAD/NAD(P)-binding domain" CG9512 27-Aug-18 DroID_v2018_08 Drer\chdh - Cele\C34C6.4 - Mmus\Chdh Hsap\CHDH viable FBgn0065141 l(3)SH105 lethal (3) SH105 http://flybase.org/reports/FBgn0065141 gene - - - "l(3)SH105, l(2)SH3 105" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0265875 lncRNA:CR44664 - http://flybase.org/reports/FBgn0265875 non_protein_coding_gene - - - "lincRNA.1000, CR44664" - CR44664 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065627 l(2)SH0793 lethal (2) SH0793 http://flybase.org/reports/FBgn0065627 gene - - - "l(2)SH0793, l(2)SH2 0793" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0000113 arch arch http://flybase.org/reports/FBgn0000113 - gene - - - arch - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive" wing FBgn0016039 mpl-1 male prothoracic leg 1 http://flybase.org/reports/FBgn0016039 - gene - - - "MPL-1, mpl-1" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0062449 CG13197 - http://flybase.org/reports/FBgn0062449 protein_coding_gene protein tyrosine phosphatase activity ; GO:0004725 | inferred from electronic annotation with InterPro:IPR016130 protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | inferred from electronic annotation with InterPro:IPR000340 protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | non-traceable author statement protein dephosphorylation ; GO:0006470 | inferred from electronic annotation with InterPro:IPR000340 protein dephosphorylation ; GO:0006470 | non-traceable author statement cellular_component ; GO:0005575 | no biological data available "CG13197, BcDNA:RE27552" "IPR000340:Dual specificity phosphatase, catalytic domain, IPR000387:Tyrosine specific protein phosphatases domain, IPR016130:Protein-tyrosine phosphatase, active site, IPR029021:Protein-tyrosine phosphatase-like, IPR020422:Dual specificity protein phosphatase domain" CG13197 27-Aug-18 DroID_v2018_08 "Drer\dusp11, Drer\rngtt" Scer\CEG1 "Cele\pir-1, Cele\ptp-4, Cele\F54C8.4" "Xtro\dusp11.2, Xtro\rngtt" "Mmus\Dusp11, Mmus\Rngtt" "Hsap\DUSP11, Hsap\RNGTT, Hsap\DUSP23" viable FBgn0025788 anon-17Ae anon-17Ae http://flybase.org/reports/FBgn0025788 - gene - - - anon-17Ae - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0016813 l(1)L15 lethal (1) L15 http://flybase.org/reports/FBgn0016813 - gene - - - "l(1)L15, L15" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0067389 c601 c601 http://flybase.org/reports/FBgn0067389 gene - - - c601 - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile,courtship behavior defective,female" FBgn0051181 CG31181 - http://flybase.org/reports/FBgn0051181 protein_coding_gene - - - "BcDNA:GH06646, CG31181" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0013664 ms(3)303 ms(3)303 http://flybase.org/reports/FBgn0013664 - gene - - - ms(3)303 - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive,male sterile" FBgn0035943 CG5653 - http://flybase.org/reports/FBgn0035943 protein_coding_gene "oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR002937, InterPro:IPR023753" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR002937, InterPro:IPR023753" - CG5653 "IPR002937:Amine oxidase, IPR023753:FAD/NAD(P)-binding domain" CG5653 27-Aug-18 DroID_v2018_08 "Drer\smox, Drer\paox1, Drer\si:dkey-275b16.2, Drer\zgc:66484" Scer\FMS1 "Cele\amx-3, Cele\amx-1, Cele\hpo-15" "Xtro\paox, Xtro\smox, Xtro\LOC100145496" "Mmus\Smox, Mmus\Kdm1b, Mmus\Paox" "Hsap\PAOX, Hsap\KDM1B, Hsap\SMOX" viable FBgn0032100 CG13108 - http://flybase.org/reports/FBgn0032100 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13108 - CG13108 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0021849 l(2)k14614 lethal (2) k14614 http://flybase.org/reports/FBgn0021849 - gene - - - l(2)k14614 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0030704 CG15916 - http://flybase.org/reports/FBgn0030704 protein_coding_gene - rRNA processing ; GO:0006364 | inferred from electronic annotation with InterPro:IPR000238 - "BcDNA:RH08992, CG15916" "IPR015946:K homology domain-like, alpha/beta, IPR000238:Ribosome-binding factor A, IPR023799:Ribosome-binding factor A domain" CG15916 27-Aug-18 DroID_v2018_08 Drer\rbfa - Cele\C25G4.3 - Mmus\Rbfa Hsap\RBFA viable FBgn0001789 l(1)Mb8 lethal (1) Mb8 http://flybase.org/reports/FBgn0001789 - gene - - - l(1)Mb8 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0035571 CG12493 - http://flybase.org/reports/FBgn0035571 protein_coding_gene double-stranded RNA binding ; GO:0003725 | inferred from sequence or structural similarity siRNA binding ; GO:0035197 | inferred from direct assay - nucleus ; GO:0005634 | inferred from direct assay "cg12493, CG12493" IPR014720:Double-stranded RNA-binding domain CG12493 27-Aug-18 DroID_v2018_08 "Drer\stau2, Drer\stau1" - Cele\stau-1 - "Mmus\Adarb1, Mmus\Stau1, Mmus\Stau2" "Hsap\ADARB1, Hsap\ADARB2, Hsap\STAU2, Hsap\STAU1" "viable,male fertile" FBgn0020365 anon-15ABa anon-15ABa http://flybase.org/reports/FBgn0020365 - gene - - - "548, anon-15ABa" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267128 lncRNA:CR45568 - http://flybase.org/reports/FBgn0267128 non_protein_coding_gene - - - CR45568 - CR45568 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0069964 CG41048 - http://flybase.org/reports/FBgn0069964 protein_coding_gene - - - CG41048 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038179 CG9312 - http://flybase.org/reports/FBgn0038179 protein_coding_gene - regulation of cell cycle ; GO:0051726 | inferred from direct assay - "CT26517, CG9312" - CG9312 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" FBgn0023522 CG11596 - http://flybase.org/reports/FBgn0023522 - protein_coding_gene carnosine N-methyltransferase activity ; GO:0030735 | inferred from sequence or structural similarity with UniProtKB:F1N9S8 carnosine N-methyltransferase activity ; GO:0030735 | inferred from biological aspect of ancestor with PANTHER:PTN000959318 carnosine metabolic process ; GO:0035498 | inferred from sequence or structural similarity with UniProtKB:F1N9S8 carnosine metabolic process ; GO:0035498 | inferred from biological aspect of ancestor with PANTHER:PTN000959318 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000959318 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000959318 "EG:39E1.1, CG11596" "IPR012901:N2227-like, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG11596 27-Aug-18 DroID_v2018_08 Drer\carnmt1 "Scer\YMR209C, Scer\YNL092W" Cele\Y48E1C.2 Xtro\carnmt1 Mmus\Carnmt1 Hsap\CARNMT1 "partially lethal - majority die,some die during pupal stage" FBgn0053136 CG33136 - http://flybase.org/reports/FBgn0053136 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG33136, NEST:bs04e10" - CG33136 27-Aug-18 DroID_v2018_08 - - Cele\ZC487.1 - - - DRSC05744 K 0.282007055 0.333004056 0.274885732 -0.077189528 -0.580113665 2.276284776 FBgn0027175 l(2)60Ai lethal (2) 60Ai http://flybase.org/reports/FBgn0027175 FBgn0027174 gene - - - "l(2)60i, l(2)60Ai" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0065564 l(2)SH0981 lethal (2) SH0981 http://flybase.org/reports/FBgn0065564 gene - - - "l(2)SH0981, l(2)SH2 0981" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0050158 CG30158 - http://flybase.org/reports/FBgn0050158 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR005225, InterPro:IPR020849 GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR001806" signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR020849 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR020849 "CG9464, CG15244, CG15243, BcDNA:RE28276, CG30158" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR020849:Small GTPase superfamily, Ras type" CG30158 27-Aug-18 DroID_v2018_08 "Drer\zgc:171704, Drer\rap1aa, Drer\ralaa, Drer\diras2, Drer\zgc:110699, Drer\diras1b, Drer\rit1, Drer\rem2, Drer\zgc:64022, Drer\si:ch73-116o1.2, Drer\zgc:152698, Drer\hrasb, Drer\rras, Drer\ralab, Drer\diras1a, Drer\rhebl1, Drer\rap2ab, Drer\rrad, Drer\nras, Drer\rasl12, Drer\ralba, Drer\rap2b, Drer\LOC100332969, Drer\zgc:153845, Drer\si:dkey-27j5.5, Drer\hrasa, Drer\rras2, Drer\kras, Drer\zgc:114118, Drer\rergla, Drer\rap2c, Drer\rap1ab, Drer\rheb, Drer\gem, Drer\rasl11a, Drer\ralbb, Drer\si:dkeyp-59c12.1, Drer\rem1, Drer\rasl10a, Drer\mras, Drer\rasd1, Drer\rasl11b, Drer\rsg1, Drer\rerglb" "Scer\RSR1, Scer\RAS2, Scer\RHB1, Scer\RAS1" Cele\ssr-2 "Xtro\rasl11b, Xtro\rap1b, Xtro\rap1a, Xtro\gem, Xtro\ralb, Xtro\nras, Xtro\rasd2, Xtro\diras2, Xtro\rala, Xtro\rerg, Xtro\diras1, Xtro\rrad, Xtro\rap2c, Xtro\rhebl1, Xtro\ras-dva, Xtro\rit1, Xtro\rasl10a, Xtro\rap2b, Xtro\rergl, Xtro\kras, Xtro\rasd1, Xtro\rem2, Xtro\LOC733456, Xtro\rem1, Xtro\rsg1, Xtro\diras3, Xtro\hras, Xtro\rap2a, Xtro\rheb" "Mmus\Rsg1, Mmus\Rap2b, Mmus\Rala, Mmus\Nras, Mmus\Rasl10b, Mmus\Rhebl1, Mmus\Mras, Mmus\Rras2, Mmus\Eras, Mmus\Hras, Mmus\Rerg, Mmus\Diras2, Mmus\Rasd1, Mmus\Rap1a, Mmus\Rras, Mmus\Rit2, Mmus\Rit1, Mmus\Rasl10a, Mmus\Rap2a, Mmus\Rem2, Mmus\Rap2c, Mmus\Rap1b, Mmus\Gem, Mmus\Rergl, Mmus\Rem1, Mmus\Ralb, Mmus\Rasl11a, Mmus\Rasl12, Mmus\Rheb, Mmus\Gm266, Mmus\Kras, Mmus\Rasl11b, Mmus\Diras1, Mmus\Rrad, Mmus\Rasd2" "Hsap\RALB, Hsap\RASL12, Hsap\KRAS, Hsap\RIT2, Hsap\RALA, Hsap\DIRAS3, Hsap\RRAD, Hsap\RRAS2, Hsap\RAP1B, Hsap\RASD2, Hsap\DIRAS1, Hsap\NRAS, Hsap\RHEB, Hsap\RERGL, Hsap\HRAS, Hsap\RASD1, Hsap\MRAS, Hsap\RASL11B, Hsap\GEM, Hsap\DIRAS2, Hsap\RIT1, Hsap\RHEBL1, Hsap\RERG, Hsap\REM1, Hsap\RAP1A, Hsap\REM2, Hsap\RASL11A, Hsap\RAP2A, Hsap\RSG1, Hsap\RASL10A, Hsap\RAP2C, Hsap\ERAS, Hsap\RASL10B, Hsap\RAP2B, Hsap\RRAS" viable FBgn0030616 RpL37a Ribosomal protein L37a http://flybase.org/reports/FBgn0030616 protein_coding_gene "structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR001569, InterPro:IPR011331, InterPro:IPR018267 RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000080456 structural constituent of ribosome ; GO:0003735 | traceable author statement" "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR001569, InterPro:IPR011331, InterPro:IPR011332, InterPro:IPR018267 cytoplasmic translation ; GO:0002181 | traceable author statement" "ribosome ; GO:0005840 | inferred from electronic annotation with InterPro:IPR001569, InterPro:IPR011331, InterPro:IPR018267 cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement" "CG9091, RpL37, RpL37a, RpL37A" "IPR018267:Ribosomal protein L37e, conserved site, IPR011331:Ribosomal protein L37ae/L37e, IPR011332:Zinc-binding ribosomal protein, IPR001569:Ribosomal protein L37e" CG9091 27-Aug-18 DroID_v2018_08 Drer\rpl37 "Scer\RPL37B, Scer\RPL37A" "Cele\rpl-37, Cele\W01D2.1" Xtro\rpl37 "Mmus\Rpl37, Mmus\Rpl37rt" Hsap\RPL37 DRSC21646 IEK 2.623496224 -1.228223652 1.381275095 -3.479774948 1.152827343 3.696013203 FBgn0040079 pkaap pkaap http://flybase.org/reports/FBgn0040079 protein_coding_gene - protein localization ; GO:0008104 | inferred from biological aspect of ancestor with PANTHER:PTN000322519 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000994571 "CG4132, BG:DS02740.4, DS02740.4, pkaap" IPR016137:RGS domain CG4132 27-Aug-18 DroID_v2018_08 Drer\akap10 Scer\RAX1 Cele\rgs-5 Xtro\akap10 Mmus\Akap10 Hsap\AKAP10 "body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0040131 l(2)22Ah lethal (2) 22Ah http://flybase.org/reports/FBgn0040131 gene - - - "B, l(2)22Ah" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0031663 CG8891 - http://flybase.org/reports/FBgn0031663 protein_coding_gene nucleoside-triphosphate diphosphatase activity ; GO:0047429 | inferred from biological aspect of ancestor with PANTHER:PTN000115987 neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype nucleoside triphosphate catabolic process ; GO:0009143 | inferred from biological aspect of ancestor with PANTHER:PTN000115987 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000115987 CG8891 "IPR002637:Ham1-like protein, IPR029001:Inosine triphosphate pyrophosphatase-like, IPR027502:Inosine triphosphate pyrophosphatase" CG8891 27-Aug-18 DroID_v2018_08 Drer\itpa Scer\HAM1 Cele\hap-1 Xtro\itpa Mmus\Itpa Hsap\ITPA "viable,fertile" FBgn0005412 dsl diskless http://flybase.org/reports/FBgn0005412 "FBgn0000498, FBgn0001583, FBgn0001622, FBgn0004658" gene - - - "l(1)discless, l(1)discless-1, l(1)C154, l(1)dsl, l(1)dl-1, l(1)DF396, l(1)10Cf, dsl" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,cell lethal,germline clone,lethal,mitotic cell cycle defective,some die during larval stage" "imaginal disc,cell cycle" FBgn0267744 lncRNA:CR46075 - http://flybase.org/reports/FBgn0267744 non_protein_coding_gene - - - "CR46075, lincRNA.255" - CR46075 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262036 CG42847 - http://flybase.org/reports/FBgn0262036 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42847 - CG42847 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264288 Su(Mir)3-1A2-2 - http://flybase.org/reports/FBgn0264288 gene - - - Su(Mir)3-1A2-2 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0044005 Su(rst)C134 Su(rst)C134 http://flybase.org/reports/FBgn0044005 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "C134, Su(rst)C134" - - 27-Aug-18 DroID_v2018_08 - - - - - - viable "secondary pigment cell,ectopic,tertiary pigment cell" FBgn0037860 CG6629 - http://flybase.org/reports/FBgn0037860 protein_coding_gene succinate dehydrogenase activity ; GO:0000104 | inferred from electronic annotation with InterPro:IPR014314 tricarboxylic acid cycle ; GO:0006099 | inferred from electronic annotation with InterPro:IPR014314 succinate dehydrogenase complex ; GO:0045281 | inferred from electronic annotation with InterPro:IPR014314 CG6629 "IPR000701:Succinate dehydrogenase/Fumarate reductase, transmembrane subunit, IPR014314:Succinate dehydrogenase, cytochrome b556 subunit" CG6629 27-Aug-18 DroID_v2018_08 Drer\sdhc "Scer\SDH3, Scer\SHH3" Cele\mev-1 Xtro\sdhc Mmus\Sdhc Hsap\SDHC FBgn0067098 H70 H70 http://flybase.org/reports/FBgn0067098 gene - - - H70 - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,eye color defective,lethal,partially lethal - majority die" "chaeta,eye,pigment cell" FBgn0063375 snoRNA:Me28S-G3277a - http://flybase.org/reports/FBgn0063375 snoRNA_gene - - - "Snr38snoRNA, CR32893, snoRNA:snR38:54Ea, snoRNA:Me28S-G3277a, Me28S-G3277a, SnR38, snoRNA:MeS28-G3277a" - CR32893 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032455 Pih1D1 Pih1D1 http://flybase.org/reports/FBgn0032455 protein_coding_gene - - microtubule associated complex ; GO:0005875 | inferred from direct assay "CG5792, Pih1D1" IPR012981:PIH1 domain CG5792 27-Aug-18 DroID_v2018_08 "Drer\dnaaf2, Drer\pih1d2, Drer\pih1d1" Scer\PIH1 Cele\F32D8.4 "Xtro\dnaaf2, Xtro\pih1d1, Xtro\pih1d2" "Mmus\Pih1d2, Mmus\Dnaaf2, Mmus\Pih1d1" "Hsap\PIH1D2, Hsap\PIH1D1, Hsap\DNAAF2" viable FBgn0264914 lncRNA:CR44105 - http://flybase.org/reports/FBgn0264914 non_protein_coding_gene - - - CR44105 - CR44105 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036638 CG13033 - http://flybase.org/reports/FBgn0036638 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE50345, CG13033" IPR004019:YLP motif CG13033 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0066372 barb barbos http://flybase.org/reports/FBgn0066372 gene molecular_function ; GO:0003674 | no biological data available learning or memory ; GO:0007611 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "barb, barbos-1" - - 27-Aug-18 DroID_v2018_08 - - - - - - "memory defective,chemical sensitive" FBgn0067417 His-Psi Histone pseudogene http://flybase.org/reports/FBgn0067417 pseudogene_attribute - - - His-Psi - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0045502 Gr10a Gustatory receptor 10a http://flybase.org/reports/FBgn0045502 protein_coding_gene sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 taste receptor activity ; GO:0008527 | non-traceable author statement olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of taste ; GO:0050909 | non-traceable author statement sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 integral component of membrane ; GO:0016021 | non-traceable author statement dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 "Gr10B1, CG32664, Gr10a, GR10a, gr10a" IPR013604:7TM chemoreceptor CG32664 27-Aug-18 DroID_v2018_08 - - "Cele\gur-3, Cele\lite-1" - - - "partially lethal - majority die,some die during pupal stage" DRSC18897 I -1.328997445 1.766443769 1.148231666 0.717794138 -0.523279283 -0.500800606 FBgn0262681 lncRNA:CR43151 - http://flybase.org/reports/FBgn0262681 non_protein_coding_gene - - - "CG43151, CR43151" - CR43151 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030695 PGRP-LE Peptidoglycan recognition protein LE http://flybase.org/reports/FBgn0030695 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR006619 peptidoglycan binding ; GO:0042834 | traceable author statement peptidoglycan binding ; GO:0042834 | non-traceable author statement N-acetylmuramoyl-L-alanine amidase activity ; GO:0008745 | NOT inferred from key residues peptidoglycan receptor activity ; GO:0016019 | traceable author statement peptidoglycan receptor activity ; GO:0016019 | non-traceable author statement peptidoglycan receptor activity ; GO:0016019 | inferred from sequence or structural similarity with UniProtKB:O76537 protein binding ; GO:0005515 | inferred from physical interaction with pirk peptidoglycan binding ; GO:0042834 | inferred from sequence or structural similarity with PGRP-SC1b signal transduction ; GO:0007165 | traceable author statement defense response to Gram-negative bacterium ; GO:0050829 | NOT inferred from mutant phenotype inferred from genetic interaction with Rel inferred from genetic interaction with Tak1 inferred from genetic interaction with Fadd innate immune response ; GO:0045087 | non-traceable author statement positive regulation of innate immune response ; GO:0045089 | inferred from mutant phenotype defense response to Gram-positive bacterium ; GO:0050830 | inferred from direct assay peptidoglycan recognition protein signaling pathway ; GO:0061057 | inferred from direct assay peptidoglycan catabolic process ; GO:0009253 | NOT inferred from key residues peptidoglycan catabolic process ; GO:0009253 | non-traceable author statement immune response ; GO:0006955 | traceable author statement defense response to bacterium ; GO:0042742 | inferred from mutant phenotype immune response ; GO:0006955 | inferred from sequence or structural similarity with UniProtKB:O76537 determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype extracellular region ; GO:0005576 | inferred from direct assay extracellular region ; GO:0005576 | non-traceable author statement "PGRP-LE, pgrp-le, CG8995, anon-WO0153538.66, PGRP, pgrp le" "IPR002502:N-acetylmuramoyl-L-alanine amidase domain, IPR006619:Peptidoglycan recognition protein family domain, metazoa/bacteria, IPR015510:Peptidoglycan recognition protein" CG8995 27-Aug-18 DroID_v2018_08 "Drer\pglyrp5, Drer\pglyrp2, Drer\pglyrp6" - - "Xtro\pglyrp2, Xtro\pglyrp1, Xtro\pglyrp1" "Mmus\Pglyrp1, Mmus\Pglyrp3, Mmus\Pglyrp4, Mmus\Pglyrp2" "Hsap\PGLYRP4, Hsap\PGLYRP1, Hsap\PGLYRP2, Hsap\PGLYRP3" "melanotic mass phenotype,heat sensitive,lethal,fertile,viable,immune response defective,short lived" "melanotic mass,heat sensitive,adult cuticle" FBgn0031107 HERC2 HECT and RLD domain containing protein 2 http://flybase.org/reports/FBgn0031107 protein_coding_gene metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR010606 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:4868 protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with HGNC:4868 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:4868 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:4868 "HERC2, CG11734, dHERC2, AF189221.1" "IPR015940:Ubiquitin-associated domain, IPR000408:Regulator of chromosome condensation, RCC1, IPR000569:HECT domain, IPR001199:Cytochrome b5-like heme/steroid binding domain, IPR009091:Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II, IPR010606:Mib-herc2, IPR008979:Galactose-binding domain-like, IPR004939:APC10/DOC domain, IPR021097:CPH domain, IPR009060:UBA-like, IPR014722:Ribosomal protein L2 domain 2" CG11734 27-Aug-18 DroID_v2018_08 "Drer\ftr97, Drer\rpgra, Drer\sergef, Drer\huwe1, Drer\herc1, Drer\rcc1, Drer\als2b, Drer\arel1, Drer\wbscr16, Drer\herc2, Drer\als2a, Drer\hace1, Drer\rccd1, Drer\rpgrb, Drer\rcbtb2, Drer\rcbtb1" "Scer\ATS1, Scer\SRM1, Scer\HUL4, Scer\FMP25" - "Xtro\als2cl, Xtro\herc1, Xtro\wbscr16, Xtro\nek9, Xtro\rcc1, Xtro\hectd3, Xtro\als2, Xtro\rcbtb1, Xtro\rcbtb2, Xtro\arel1, Xtro\herc2, Xtro\hace1" "Mmus\Rcc1, Mmus\Herc1, Mmus\Huwe1, Mmus\Gm15800, Mmus\Wbscr16, Mmus\Nek9, Mmus\Herc2, Mmus\Rcbtb2, Mmus\Rccd1, Mmus\Als2, Mmus\Rpgr, Mmus\Arel1, Mmus\Hace1, Mmus\Sergef, Mmus\Rcbtb1, Mmus\Hectd3" "Hsap\RCC1L, Hsap\RPGR, Hsap\HECTD3, Hsap\RCC1, Hsap\HACE1, Hsap\RCBTB1, Hsap\SERGEF, Hsap\HUWE1, Hsap\ALS2, Hsap\AREL1, Hsap\NEK9, Hsap\RCCD1, Hsap\HERC1, Hsap\RCBTB2, Hsap\HERC2, Hsap\HECTD4" viable FBgn0010265 RpS13 Ribosomal protein S13 http://flybase.org/reports/FBgn0010265 FBgn0021990 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from direct assay structural constituent of ribosome ; GO:0003735 | traceable author statement small ribosomal subunit rRNA binding ; GO:0070181 | inferred from biological aspect of ancestor with PANTHER:PTN000223267 "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR000589, InterPro:IPR012606 cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 cytoplasmic translation ; GO:0002181 | traceable author statement" cytosolic ribosome ; GO:0022626 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay ribosome ; GO:0005840 | inferred from direct assay nuclear chromosome ; GO:0000228 | inferred from direct assay nucleolus ; GO:0005730 | inferred from direct assay cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement "M(2)32A, S13, M(2)32, l(2)k09614, Rp17, CG13389, RpS13, M(2)29B, RPS13, Rp S13, Rps 13" "IPR000589:Ribosomal protein S15, IPR009068:S15/NS1, RNA-binding, IPR012606:Ribosomal protein S13/S15, N-terminal, IPR023029:Ribosomal protein S15P" CG13389 27-Aug-18 DroID_v2018_08 Drer\rps13 Scer\RPS13 Cele\rps-13 Xtro\rps13 Mmus\Rps13 Hsap\RPS13 embryonic stage -- adult stage "developmental rate defective,lethal,recessive,visible,Minute,dominant,size defective,lethal - all die before end of pupal stage,some die during pupal stage" "prothoracic gland,macrochaeta,scutellar bristle,adult heart" DRSC03419 IEK 0.127403158 -1.80179533 -6.300514182 -5.071674796 3.76989015 2.252644918 FBgn0267932 lncRNA:CR46212 - http://flybase.org/reports/FBgn0267932 non_protein_coding_gene - - - "CR46212, lincRNA.491" - CR46212 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0014874 Pt5 Protein 5 http://flybase.org/reports/FBgn0014874 - gene - - - Pt5 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0064169 l(3)64.63 lethal (3) 64.63 http://flybase.org/reports/FBgn0064169 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available l(3)64.63 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0259943 Ttd8 TRPL translocation defect 8 http://flybase.org/reports/FBgn0259943 protein_coding_gene - - - Ttd8 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060695 l(3)S073006 lethal (3) S073006 http://flybase.org/reports/FBgn0060695 gene - - - "0730/06, l(3)S073006" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0005207 l(3)e lethal on ebony http://flybase.org/reports/FBgn0005207 - gene - - - l(3)e - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0034687 CG11475 - http://flybase.org/reports/FBgn0034687 protein_coding_gene enzyme binding ; GO:0019899 | inferred from sequence or structural similarity with HGNC:17872 regulation of response to DNA damage stimulus ; GO:2001020 | inferred from sequence or structural similarity with HGNC:17872 protein methylation ; GO:0006479 | inferred from sequence or structural similarity with HGNC:17872 cellular_component ; GO:0005575 | no biological data available CG11475 IPR002791:Domain of unknown function DUF89 CG11475 27-Aug-18 DroID_v2018_08 Drer\armt1 Scer\YMR027W Cele\F31D4.2 Xtro\armt1 Mmus\Armt1 Hsap\ARMT1 viable FBgn0038484 CG5246 - http://flybase.org/reports/FBgn0038484 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP96, BcDNA:LP06628, CG5246" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG5246 27-Aug-18 DroID_v2018_08 "Drer\LOC558805, Drer\LOC103908930, Drer\prss59.1, Drer\prss59.2, Drer\LOC560023, Drer\zmp:0000001088" - "Cele\nhl-3, Cele\svh-1, Cele\try-1" - "Mmus\Klk1b5, Mmus\Try5, Mmus\Egfbp2, Mmus\Prss1, Mmus\Klk15, Mmus\Klk1b4, Mmus\Ovch2, Mmus\2210010C04Rik, Mmus\Klk14, Mmus\Prss55, Mmus\Klk7, Mmus\Klk1b11" "Hsap\KLK14, Hsap\OVCH2, Hsap\PRSS3, Hsap\CFD, Hsap\OVCH1" viable FBgn0024294 Spn43Aa Serpin 43Aa http://flybase.org/reports/FBgn0024294 "FBgn0033144, FBgn0063809" protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from biological aspect of ancestor with PANTHER:PTN000156122 negative regulation of proteolysis ; GO:0045861 | inferred from sequence model extracellular space ; GO:0005615 | inferred from sequence model extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000156122 "CG12172, Ser1, SER1, anon-WO0118057.1, Spn43Aa, Spn43 Aa, Spn43A" "IPR000215:Serpin family, IPR023796:Serpin domain" CG12172 27-Aug-18 DroID_v2018_08 "Drer\serpina1l, Drer\serpine2, Drer\serpine1, Drer\si:ch211-186e20.7, Drer\zgc:173729, Drer\serpina7, Drer\zgc:174259, Drer\serpind1, Drer\serpina10a, Drer\serpinb1l1, Drer\serpinh1b, Drer\serpinc1, Drer\serpinb1l2, Drer\serpinb1l3, Drer\serpinh1a, Drer\serpini1, Drer\serpinb1l4, Drer\serpine3, Drer\serpinb1, Drer\serpinh2, Drer\si:ch1073-416d2.3" - "Cele\srp-3, Cele\srp-6, Cele\srp-7, Cele\srp-8, Cele\srp-1, Cele\srp-2" "Xtro\serpinb11, Xtro\serpini1, Xtro\serpina3, Xtro\serpinb6, Xtro\serpine2, Xtro\serpinb5, Xtro\serpine1, Xtro\serpind1, Xtro\serpinb1, Xtro\serpina1, Xtro\serpina3k, Xtro\serpina10, Xtro\serpinb4, Xtro\serpinc1, Xtro\serpina3m, Xtro\serpini2" "Mmus\Serpinb8, Mmus\Serpinb7, Mmus\Serpina16, Mmus\Serpinb3b, Mmus\Serpinb5, Mmus\Serpina3g, Mmus\Serpina3j, Mmus\Serpine1, Mmus\Serpinb6a, Mmus\Serpina9, Mmus\Serpina1c, Mmus\Serpina3i, Mmus\Serpina3c, Mmus\Serpind1, Mmus\Serpini2, Mmus\Serpinb6d, Mmus\Serpinb9e, Mmus\Serpinb9c, Mmus\Serpinb6e, Mmus\Serpinb12, Mmus\Gm11397, Mmus\Serpina3k, Mmus\Serpinb1b, Mmus\Serpinb3c, Mmus\Serping1, Mmus\Serpina12, Mmus\Serpine2, Mmus\Serpinb3d, Mmus\Serpinh1, Mmus\Serpina3a, Mmus\Serpinb6b, Mmus\Serpine3, Mmus\Serpinb9, Mmus\Serpinb1a, Mmus\Serpinb9g, Mmus\Serpinb9f, Mmus\Serpina7, Mmus\Serpina1d, Mmus\Serpinb2, Mmus\Serpina5, Mmus\Serpina1e, Mmus\Serpinb1c, Mmus\Serpinb9d, Mmus\Serpinb13, Mmus\Serpinb10, Mmus\Serpinc1, Mmus\Serpina1a, Mmus\Serpina11, Mmus\Serpina3n, Mmus\Serpinb11, Mmus\Serpina3f, Mmus\Serpinb6c, Mmus\Serpina6, Mmus\Serpinb3a, Mmus\Serpina10, Mmus\Serpini1, Mmus\Serpinb9b" "Hsap\SERPINA10, Hsap\SERPINE3, Hsap\SERPINA5, Hsap\SERPINA9, Hsap\SERPINI1, Hsap\SERPINA12, Hsap\SERPINB10, Hsap\SERPINB7, Hsap\SERPINE1, Hsap\SERPINA11, Hsap\SERPINB12, Hsap\SERPINA3, Hsap\SERPINA7, Hsap\SERPINE2, Hsap\SERPING1, Hsap\SERPINB4, Hsap\SERPINB9, Hsap\SERPINA6, Hsap\SERPINB8, Hsap\SERPINB6, Hsap\SERPINB11, Hsap\SERPINB3, Hsap\SERPINB5, Hsap\SERPINI2, Hsap\SERPINB1, Hsap\SERPINA1, Hsap\HMSD, Hsap\SERPIND1, Hsap\SERPINA4, Hsap\SERPINH1, Hsap\SERPINB2, Hsap\SERPINC1, Hsap\SERPINB13" viable FBgn0001166 gy gouty legs http://flybase.org/reports/FBgn0001166 - gene - - - gy - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile,visible" "leg,metatarsus & metathoracic leg" FBgn0024863 l(3)05471 lethal (3) 05471 http://flybase.org/reports/FBgn0024863 - gene - - - "5471, l(3)05471" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0035063 CG3594 - http://flybase.org/reports/FBgn0035063 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity - - "cg3594, CG3594, Eap" IPR000504:RNA recognition motif domain CG3594 27-Aug-18 DroID_v2018_08 "Drer\ncl, Drer\rbm24b, Drer\syncripl, Drer\rbm19, Drer\syncrip, Drer\hnrnpa0a, Drer\rbm24a, Drer\hnrnpa0b" "Scer\MRD1, Scer\NOP12" "Cele\F11A10.7, Cele\sqd-1" Xtro\rbm19 "Mmus\Rbm38, Mmus\Syncrip, Mmus\Rbm24, Mmus\Hnrnpa0, Mmus\Hnrnpr, Mmus\Rbm19, Mmus\Ncl, Mmus\Rbm34" "Hsap\HNRNPR, Hsap\NCL, Hsap\RBMXL3, Hsap\RBM19, Hsap\RBM24, Hsap\SYNCRIP, Hsap\HNRNPA0, Hsap\RBM34, Hsap\RBM38, Hsap\SRSF2, Hsap\SRSF10" "viable,visible" trichogen cell FBgn0024637 l(2)k13531 lethal (2) k13531 http://flybase.org/reports/FBgn0024637 - gene - - - "135/31, l(2)k13531" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" imaginal disc FBgn0014310 l(3)ry102 lethal (3) ry102 http://flybase.org/reports/FBgn0014310 - gene - - - l(3)ry102 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0011254 ms(3)98B male sterile (3) 98B http://flybase.org/reports/FBgn0011254 - gene - spermatid development ; GO:0007286 | inferred from mutant phenotype - "ms(3)06302, ms(3)98B" - - 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,recessive,male semi-sterile" FBgn0011554 etaTry etaTrypsin http://flybase.org/reports/FBgn0011554 FBgn0014415 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from sequence or structural similarity serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "SP57, DmEtaTry, 169C4S, etaTry, anon-sts17, ESTS:169C4S, CG12386" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG12386 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-33m11.7, Drer\zmp:0000001088" - "Cele\try-1, Cele\svh-1" - "Mmus\Tmprss11c, Mmus\Prss55" Hsap\TMPRSS11B viable FBgn0283503 Neurl4 Neuralized E3 ubiquitin protein ligase 4 http://flybase.org/reports/FBgn0283503 protein_coding_gene - oogenesis ; GO:0048477 | inferred from mutant phenotype centrosome ; GO:0005813 | inferred from direct assay "CG46284, blue, CG6451, Neurl4, Blue" - CG46284 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0004752 l(3)89Be lethal (3) 89Be http://flybase.org/reports/FBgn0004752 - gene - - - l(3)89Be - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0265846 lncRNA:CR44635 - http://flybase.org/reports/FBgn0265846 non_protein_coding_gene - - - CR44635 - CR44635 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0015759 MHC95F-associated-protein MHC95F-associated protein http://flybase.org/reports/FBgn0015759 - gene - - - MHC95F-associated-protein - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0016856 l(1)N37 lethal (1) N37 http://flybase.org/reports/FBgn0016856 - gene - - - "l(1)N37, N37" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0027191 l(2)60A-A lethal (2) 60A-A http://flybase.org/reports/FBgn0027191 - gene - - - l(2)60A-A - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0052551 CG32551 - http://flybase.org/reports/FBgn0052551 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32551 - CG32551 27-Aug-18 DroID_v2018_08 - - - - - - DRSC19260 E 0.371493573 0.316207893 -1.728945125 0.398283993 0.069789337 0.27659687 FBgn0004967 plph polyphase http://flybase.org/reports/FBgn0004967 - gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "plp, plph" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,maternal effect,lethal - all die before end of larval stage,some die during larval stage,rescuable maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0082575 CycA::tor CycA::tor http://flybase.org/reports/FBgn0082575 engineered_fusion_gene - - - CycA::tor - - 27-Aug-18 DroID_v2018_08 - - - - - - mitotic cell cycle defective S phase | ectopichs.2sev FBgn0032968 CG11634 - http://flybase.org/reports/FBgn0032968 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT09142, CG11634" IPR009961:Protein of unknown function DUF1487 CG11634 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0039769 CG15534 - http://flybase.org/reports/FBgn0039769 protein_coding_gene sphingomyelin phosphodiesterase activity ; GO:0004767 | inferred from electronic annotation with InterPro:IPR011160 sphingomyelin catabolic process ; GO:0006685 | inferred from electronic annotation with InterPro:IPR011160 - "aSMase, CG15534, alphaSmase" "IPR004843:Calcineurin-like phosphoesterase domain, ApaH type, IPR008139:Saposin B type domain, IPR011160:Sphingomyelin phosphodiesterase, IPR029052:Metallo-dependent phosphatase-like" CG15534 27-Aug-18 DroID_v2018_08 Drer\smpd1 Scer\PPN1 "Cele\asm-2, Cele\ZK856.5, Cele\asm-3, Cele\asm-1" - Mmus\Smpd1 Hsap\SMPD1 viable FBgn0037485 CG14606 - http://flybase.org/reports/FBgn0037485 protein_coding_gene sugar:proton symporter activity ; GO:0005351 | inferred from biological aspect of ancestor with PANTHER:PTN000627328 glucose transmembrane transporter activity ; GO:0005355 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 glucose import ; GO:0046323 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 phagocytosis ; GO:0006909 | inferred from mutant phenotype hexose transmembrane transport ; GO:0035428 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005828, InterPro:IPR005829" CG14606 "IPR005829:Sugar transporter, conserved site, IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG14606 27-Aug-18 DroID_v2018_08 "Drer\slc2a6, Drer\slc2a8, Drer\LOC101882338, Drer\slc2a13b, Drer\slc2a10, Drer\slc2a12" "Scer\YFL040W, Scer\ITR2, Scer\HXT10, Scer\HXT4, Scer\HXT17, Scer\HXT14, Scer\MPH2, Scer\ITR1, Scer\VBA2, Scer\HXT3, Scer\HXT5, Scer\AZR1, Scer\SNF3, Scer\VBA1, Scer\ATR1, Scer\YMR279C, Scer\VBA3, Scer\HXT11, Scer\VBA4, Scer\YDL199C, Scer\HXT6, Scer\MAL31, Scer\HXT15, Scer\STL1, Scer\HXT16, Scer\HXT9, Scer\VBA5, Scer\MAL11, Scer\SGE1, Scer\GEX1, Scer\HXT7, Scer\ENB1, Scer\HXT13, Scer\YDR387C, Scer\HXT1, Scer\RGT2, Scer\GEX2, Scer\MPH3, Scer\GAL2, Scer\HXT8, Scer\HXT2" - "Xtro\slc2a10, Xtro\slc2a8, Xtro\slc2a6, Xtro\slc2a12" "Mmus\Slc2a13, Mmus\Slc2a6, Mmus\Slc2a12, Mmus\Slc2a8, Mmus\Slc2a10" "Hsap\SLC2A12, Hsap\SLC2A6, Hsap\SLC2A13, Hsap\SLC2A8, Hsap\SLC2A10" viable FBgn0037447 Neurochondrin Neurochondrin http://flybase.org/reports/FBgn0037447 protein_coding_gene molecular_function ; GO:0003674 | no biological data available muscle system process ; GO:0003012 | inferred from expression pattern inferred from genetic interaction with Mhc neuronal cell body ; GO:0043025 | inferred from sequence or structural similarity with UniProtKB:O35095 dendrite ; GO:0030425 | inferred from sequence or structural similarity with UniProtKB:O35095 "Neurochondrin, CG2330" "IPR008709:Neurochondrin, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold" CG2330 27-Aug-18 DroID_v2018_08 Drer\ncdn - - Xtro\ncdn Mmus\Ncdn Hsap\NCDN FBgn0027120 l(3)rI327 lethal (3) rI327 http://flybase.org/reports/FBgn0027120 - gene - - - "l(?)rI327, l(3)rI327" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0036868 ms(3)76Ba male sterile (3) 76Ba http://flybase.org/reports/FBgn0036868 protein_coding_gene molecular_function ; GO:0003674 | no biological data available spermatogenesis ; GO:0007283 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG14087, ms(3)76Ba" - CG14087 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,viable" FBgn0266067 lncRNA:CR44820 - http://flybase.org/reports/FBgn0266067 non_protein_coding_gene - - - CR44820 - CR44820 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0083124 Uhg4 Uhg4 http://flybase.org/reports/FBgn0083124 non_protein_coding_gene - - - "Uhg4, dUhg4, CR42451" - CR42451 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0027294 l(1)G0150 lethal (1) G0150 http://flybase.org/reports/FBgn0027294 - gene - - - l(1)G0150 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" "wing,eye" FBgn0026323 Tak1 TGF-beta activated kinase 1 http://flybase.org/reports/FBgn0026323 "FBgn0031120, FBgn0042230" protein_coding_gene "magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR017421 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 protein binding ; GO:0005515 | inferred from physical interaction with S6k MAP kinase kinase kinase activity ; GO:0004709 | inferred from mutant phenotype MAP kinase kinase kinase activity ; GO:0004709 | traceable author statement ubiquitin protein ligase binding ; GO:0031625 | inferred from physical interaction with POSH protein kinase activity ; GO:0004672 | non-traceable author statement JUN kinase kinase kinase activity ; GO:0004706 | inferred from mutant phenotype" regulation of autophagy ; GO:0010506 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype positive regulation of antibacterial peptide biosynthetic process ; GO:0006963 | traceable author statement dorsal closure ; GO:0007391 | traceable author statement activation of JNKK activity ; GO:0007256 | inferred from mutant phenotype innate immune response ; GO:0045087 | traceable author statement defense response to Gram-negative bacterium ; GO:0050829 | inferred from genetic interaction with PGRP-LE dorsal closure ; GO:0007391 | inferred from mutant phenotype apoptotic process ; GO:0006915 | inferred from genetic interaction with hid inferred from genetic interaction with rpr inferred from genetic interaction with grim positive regulation of JNK cascade ; GO:0046330 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement cellular response to lipopolysaccharide ; GO:0071222 | inferred from mutant phenotype peptidoglycan recognition protein signaling pathway ; GO:0061057 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype ommatidial rotation ; GO:0016318 | inferred from mutant phenotype notum morphogenesis ; GO:0048802 | inferred from mutant phenotype JNK cascade ; GO:0007254 | inferred from genetic interaction with bsk inferred from genetic interaction with hep positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria ; GO:0006964 | inferred from mutant phenotype immune response ; GO:0006955 | inferred from mutant phenotype defense response to virus ; GO:0051607 | inferred from mutant phenotype immune response ; GO:0006955 | traceable author statement I-kappaB kinase/NF-kappaB signaling ; GO:0007249 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay "dTAK1, DTAK1, TAK, D-tak, dTak1, TAK-1, dTAK, tak1, TAK1, tak, D10, DmTak1, CG18492, CG1388, DTak1, DTak, Tak 1, Tak1, dtak1, dTAK-1, dTak, Tak, D-TAK" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR017421:Mitogen-activated protein (MAP) kinase kinase kinase 7, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain" CG18492 27-Aug-18 DroID_v2018_08 "Drer\LOC405768, Drer\map3k7, Drer\igf1rb, Drer\ripk2, Drer\ripk4, Drer\zak, Drer\mos, Drer\ripk3, Drer\dstyk, Drer\tyro3, Drer\ripk1l, Drer\ptk2aa, Drer\map3k10, Drer\tnk2b, Drer\si:ch211-120p12.3, Drer\map3k9, Drer\lrrk2, Drer\pbk" Scer\ARK1 "Cele\mom-4, Cele\kin-26, Cele\Y105C5A.24, Cele\let-23, Cele\F57B9.8" "Xtro\ripk1, Xtro\map3k7, Xtro\pbk, Xtro\abl2, Xtro\dstyk, Xtro\zak, Xtro\map3k9, Xtro\mlkl, Xtro\map3k10, Xtro\lrrk1, Xtro\ripk4, Xtro\lrrk2, Xtro\ankk1, Xtro\abl1, Xtro\LOC100490493" "Mmus\Pbk, Mmus\Mos, Mmus\Zak, Mmus\Map3k11, Mmus\Ripk3, Mmus\BC021891, Mmus\Mlkl, Mmus\Map3k9, Mmus\Ripk2, Mmus\Map3k7, Mmus\Ripk1, Mmus\Map3k10, Mmus\Lrrk1, Mmus\Ripk4, Mmus\Dstyk, Mmus\Lrrk2" "Hsap\DSTYK, Hsap\RIPK3, Hsap\MAP3K10, Hsap\LRRK1, Hsap\LRRK2, Hsap\PBK, Hsap\RIPK1, Hsap\RIPK4, Hsap\MAP3K7, Hsap\MAP3K11, Hsap\MAP3K20, Hsap\RIPK2, Hsap\MAP3K9, Hsap\MAP3K21, Hsap\MOS, Hsap\ABL1, Hsap\MLKL, Hsap\ALK" "visible,size defective,immune response defective,wild-type,viable,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,partially lethal - majority die,increased cell death,lethal - all die before end of pupal stage,some die during pupal stage,neuroanatomy defective,planar polarity defective,lethal" "eye,embryonic/first instar larval cuticle,anterior,pupa,eye disc,photoreceptor cell,denticle belt,denticle row 1,neuroblast | larval stage,mesothoracic tergum,microchaeta,embryonic head,mouth hooks,embryo,dorsal,interommatidial bristle,secondary pigment cell,tertiary pigment cell,eye photoreceptor cell,ommatidium,basement membraneptc-559.1" DRSC20390 I 0.406784594 -2.323382771 -0.285452844 0.024562052 0.02045284 -0.562214973 FBgn0082329 HM840 HM840 http://flybase.org/reports/FBgn0082329 gene - - - HM840 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0083032 snoRNA:Psi18S-525g snoRNA:Psi18S-525g http://flybase.org/reports/FBgn0083032 snoRNA_gene - - - "snoRNA:Psi18S-525g, psi18S-525g, CR34580" - CR34580 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030895 CG7135 - http://flybase.org/reports/FBgn0030895 protein_coding_gene - - - CG7135 "IPR015897:CHK kinase-like, IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain" CG7135 27-Aug-18 DroID_v2018_08 - - "Cele\C29F7.1, Cele\nhr-246, Cele\H06H21.8, Cele\C29F7.2" - - - viable FBgn0043529 anon-AE003814.1 anon-AE003814.1 http://flybase.org/reports/FBgn0043529 gene - - - anon-AE003814.1 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0022007 l(2)k09217 lethal (2) k09217 http://flybase.org/reports/FBgn0022007 - gene - - - l(2)k09217 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0085395 Shawl Shaw-like http://flybase.org/reports/FBgn0085395 protein_coding_gene voltage-gated cation channel activity ; GO:0022843 | inferred from sequence or structural similarity with eag voltage-gated potassium channel activity ; GO:0005249 | inferred from biological aspect of ancestor with PANTHER:PTN000164970 protein homooligomerization ; GO:0051260 | inferred from electronic annotation with InterPro:IPR003131 potassium ion transport ; GO:0006813 | inferred from sequence or structural similarity with eag potassium ion transmembrane transport ; GO:0071805 | inferred from biological aspect of ancestor with PANTHER:PTN000164970 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000164970 voltage-gated potassium channel complex ; GO:0008076 | inferred from sequence or structural similarity with eag "CG13111, CG4450, shawl, Shawl, CG34366, Kv3, Kv3.2" "IPR011333:SKP1/BTB/POZ domain, IPR003968:Potassium channel, voltage dependent, Kv, IPR003974:Potassium channel, voltage dependent, Kv3, IPR003131:Potassium channel tetramerisation-type BTB domain, IPR005821:Ion transport domain, IPR028325:Voltage-gated potassium channel, IPR000210:BTB/POZ domain, IPR015572:Potassium channel, voltage dependent, Shaw, invertebrate" CG34366 27-Aug-18 DroID_v2018_08 "Drer\kcnv2a, Drer\kcng2, Drer\si:dkey-201i6.2, Drer\kcnc1a, Drer\si:dkey-192j17.1, Drer\kcnc2, Drer\kcnf1b, Drer\kcnc1b, Drer\kcnb2, Drer\kcnc3a, Drer\kcng4a, Drer\kcns3b, Drer\kcng4b, Drer\si:rp71-39b20.4, Drer\kcnf1a, Drer\kcnv2b, Drer\kcnc3b, Drer\si:dkey-43k4.5, Drer\kcnc4, Drer\si:ch73-334d15.4, Drer\kcnb1, Drer\kcns3a" - "Cele\shw-1, Cele\shw-3, Cele\egl-36" "Xtro\kcnv2, Xtro\kcnf1, Xtro\kcng4, Xtro\kcng2, Xtro\kcnc4, Xtro\kcnb2, Xtro\kcng1, Xtro\kcns3, Xtro\kcns1, Xtro\kcnb1, Xtro\kcnv1" "Mmus\Kcnc2, Mmus\Kcnc4, Mmus\Kcnc1, Mmus\Kcnv1, Mmus\Kcns2, Mmus\Kcng1, Mmus\Kcnf1, Mmus\Kcng4, Mmus\Kcng2, Mmus\Kcnc3, Mmus\Kcns3, Mmus\Kcnv2, Mmus\Kcnb1, Mmus\Kcng3, Mmus\Kcns1, Mmus\Kcnb2" "Hsap\KCNC2, Hsap\KCNS2, Hsap\KCNB2, Hsap\KCNG3, Hsap\KCNS3, Hsap\KCNB1, Hsap\KCNS1, Hsap\KCNC3, Hsap\KCNF1, Hsap\KCNG1, Hsap\KCNG4, Hsap\KCNC4, Hsap\KCNV1, Hsap\KCNC1, Hsap\KCNG2, Hsap\KCNV2" FBgn0033429 CG12929 - http://flybase.org/reports/FBgn0033429 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12929 IPR018908:Putative transmembrane family 234 CG12929 27-Aug-18 DroID_v2018_08 Drer\tmem234 - Cele\F53F10.8 Xtro\tmem234 Mmus\Tmem234 Hsap\TMEM234 viable FBgn0001804 l(1)Mc32 lethal (1) Mc32 http://flybase.org/reports/FBgn0001804 - gene - - - l(1)Mc32 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0267611 lncRNA:CR45949 - http://flybase.org/reports/FBgn0267611 non_protein_coding_gene - - - CR45949 - CR45949 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033131 CR12842 - http://flybase.org/reports/FBgn0033131 pseudogene_attribute - - - "CR12842, CG12842" - CR12842 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" FBgn0031756 CG13992 - http://flybase.org/reports/FBgn0031756 protein_coding_gene - - - CG13992 - CG13992 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0085196 CG34167 - http://flybase.org/reports/FBgn0085196 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34167 - CG34167 27-Aug-18 DroID_v2018_08 - - Cele\W08E12.2 - Mmus\Lce1h Hsap\KRTAP5-6 FBgn0267166 lncRNA:CR45606 - http://flybase.org/reports/FBgn0267166 non_protein_coding_gene - - - CR45606 - CR45606 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0261984 Ire1 Inositol-requiring enzyme-1 http://flybase.org/reports/FBgn0261984 protein_coding_gene "protein kinase activity ; GO:0004672 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR008271 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719 endoribonuclease activity ; GO:0004521 | inferred from mutant phenotype protein kinase activity ; GO:0004672 | non-traceable author statement endoribonuclease activity ; GO:0004521 | inferred from direct assay" "protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR008271 response to endoplasmic reticulum stress ; GO:0034976 | inferred from direct assay protein phosphorylation ; GO:0006468 | non-traceable author statement compound eye photoreceptor fate commitment ; GO:0001752 | NOT inferred from mutant phenotype regulation of RNA splicing ; GO:0043484 | inferred from direct assay mRNA endonucleolytic cleavage involved in unfolded protein response ; GO:0070055 | inferred from mutant phenotype endoplasmic reticulum unfolded protein response ; GO:0030968 | inferred from direct assay compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from mutant phenotype rhabdomere morphogenesis ; GO:0061541 | inferred from mutant phenotype Golgi organization ; GO:0007030 | inferred from mutant phenotype endoplasmic reticulum unfolded protein response ; GO:0030968 | inferred from mutant phenotype mRNA catabolic process ; GO:0006402 | inferred from mutant phenotype" - "CG4583, ERN1, ire1, Ire1, ire-1, IRE1, dire-1, IRE-like, Ire-1, dIRE1, Ire" "IPR018391:Pyrrolo-quinoline quinone beta-propeller repeat, IPR033523:Serine/threonine-protein kinase/endoribonuclease IRE2, IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR010513:KEN domain, IPR011009:Protein kinase-like domain, IPR011047:Quinoprotein alcohol dehydrogenase-like superfamily, IPR018997:PUB domain" CG4583 27-Aug-18 DroID_v2018_08 "Drer\LOC100334396, Drer\ern1, Drer\LOC101886687, Drer\ern2" Scer\IRE1 Cele\ire-1 Xtro\ern2 "Mmus\Ern2, Mmus\Ern1, Mmus\Rnasel" "Hsap\ERN2, Hsap\RNASEL, Hsap\ERN1" FBgn0034242 CG14480 - http://flybase.org/reports/FBgn0034242 protein_coding_gene - - - CG14480 "IPR019331:FAM192A/Fyv6, N-terminal" CG14480 27-Aug-18 DroID_v2018_08 Drer\fam192a - "Cele\C25A1.1, Cele\ZC190.9, Cele\Y75D11A.1" Xtro\fam192a Mmus\Fam192a Hsap\FAM192A viable FBgn0024221 ird6 immune response deficient 6 http://flybase.org/reports/FBgn0024221 - gene - positive regulation of antibacterial peptide biosynthetic process ; GO:0006963 | inferred from mutant phenotype - ird6 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,immune response defective,melanotic mass phenotype" melanotic mass FBgn0264704 lncRNA:CR43973 - http://flybase.org/reports/FBgn0264704 non_protein_coding_gene - - - CR43973 - CR43973 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0016796 exl exu-like http://flybase.org/reports/FBgn0016796 - gene - - - "Exl, exl" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263854 l(3)YD1073 - http://flybase.org/reports/FBgn0263854 gene - - - l(3)YD1073 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0261840 pre-mod(mdg4)-X - http://flybase.org/reports/FBgn0261840 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "pre-mod(mdg4)-X, CG42772, RX" "IPR007588:Zinc finger, FLYWCH-type" CG42772 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033921 tej tejas http://flybase.org/reports/FBgn0033921 protein_coding_gene - piRNA biosynthetic process ; GO:1990511 | inferred from genetic interaction with tapas negative regulation of transposition ; GO:0010529 | inferred from mutant phenotype karyosome formation ; GO:0030717 | inferred from mutant phenotype P granule ; GO:0043186 | inferred from direct assay "anon-EST:fe1D11, Tej, CG8589, tej" "IPR025605:OST-HTH/LOTUS domain, IPR002999:Tudor domain" CG8589 27-Aug-18 DroID_v2018_08 "Drer\tdrkh, Drer\si:dkeyp-93d12.1, Drer\si:ch211-189e2.3, Drer\tdrd1, Drer\tdrd7a, Drer\tdrd6, Drer\sb:cb829, Drer\tdrd5" - "Cele\F32E10.5, Cele\eri-5, Cele\ekl-1, Cele\tag-250, Cele\rsd-6" "Xtro\tdrd5, Xtro\tdrd7" "Mmus\Tdrd1, Mmus\Tdrd12, Mmus\Tdrd6, Mmus\Tdrd7, Mmus\Tdrkh, Mmus\Tdrd5" "Hsap\TDRD5, Hsap\TDRD15, Hsap\TDRD1, Hsap\TDRD10, Hsap\TDRKH, Hsap\TDRD12, Hsap\TDRD6, Hsap\TDRD7" "female sterile,recessive,viable,female sterile germline-dependent,female semi-sterile" FBgn0262057 Spn77Ba Serpin 77Ba http://flybase.org/reports/FBgn0262057 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from biological aspect of ancestor with PANTHER:PTN000156122 negative regulation of proteolysis ; GO:0045861 | inferred from sequence model negative regulation of melanization defense response ; GO:0035009 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from direct assay "CG6680, Spn77Ba, spn77Ba, l(3)77ABi, Q0E8C8_DROME" "IPR000215:Serpin family, IPR023796:Serpin domain" CG6680 27-Aug-18 DroID_v2018_08 "Drer\agt, Drer\serping1, Drer\serpinf1, Drer\serpini1, Drer\serpinf2a, Drer\serpind1, Drer\serpinf2b" - "Cele\srp-8, Cele\srp-7, Cele\srp-3, Cele\srp-1, Cele\C28G1.2, Cele\srp-2, Cele\srp-6" - "Mmus\Serpind1, Mmus\Serpinb7, Mmus\Serpinf2, Mmus\Serpini2, Mmus\Serpini1, Mmus\Serpinf1, Mmus\Agt" "Hsap\SERPIND1, Hsap\SERPINF1, Hsap\AGT, Hsap\SERPINB7, Hsap\SERPINI2, Hsap\SERPINF2, Hsap\SERPINI1" FBgn0003062 Fib Fibrillarin http://flybase.org/reports/FBgn0003062 - protein_coding_gene rRNA methyltransferase activity ; GO:0008649 | inferred from biological aspect of ancestor with PANTHER:PTN000036740 histone-glutamine methyltransferase activity ; GO:1990259 | inferred from biological aspect of ancestor with PANTHER:PTN000036740 RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000036740 "tRNA processing ; GO:0008033 | inferred from electronic annotation with InterPro:IPR000692, InterPro:IPR020813 cellular response to starvation ; GO:0009267 | inferred from expression pattern rRNA methylation ; GO:0031167 | inferred from biological aspect of ancestor with PANTHER:PTN000036740 box C/D snoRNA 3'-end processing ; GO:0000494 | inferred from biological aspect of ancestor with PANTHER:PTN000036740 centrosome organization ; GO:0051297 | inferred from mutant phenotype histone glutamine methylation ; GO:1990258 | inferred from biological aspect of ancestor with PANTHER:PTN000036740" dense fibrillar component ; GO:0001651 | inferred from sequence or structural similarity with UniProtKB:P22509 small nucleolar ribonucleoprotein complex ; GO:0005732 | inferred from sequence or structural similarity box C/D snoRNP complex ; GO:0031428 | inferred from biological aspect of ancestor with PANTHER:PTN000036740 nucleolus ; GO:0005730 | inferred from direct assay small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from sequence or structural similarity Cajal body ; GO:0015030 | inferred from direct assay small-subunit processome ; GO:0032040 | inferred from biological aspect of ancestor with PANTHER:PTN000036740 nucleolus ; GO:0005730 | "GCR-6, pen59C5, Pen59C5, GCR6, CG9888, Fib, Fibri, fib, fibrillarin" "IPR000692:Fibrillarin, IPR020813:Fibrillarin, conserved site, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG9888 27-Aug-18 DroID_v2018_08 Drer\fbl Scer\NOP1 "Cele\C06E1.9, Cele\fib-1" Xtro\fbl "Mmus\Fbll1, Mmus\Fbl" Hsap\FBL female sterile FBgn0054047 lncRNA:CR34047 - http://flybase.org/reports/FBgn0054047 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BP1083, HDC08545, CG34047, CR34047" - CR34047 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263315 Ubi::Ecol\birA - http://flybase.org/reports/FBgn0263315 engineered_fusion_gene - - - Ubi::Ecol\birA - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001685 l(1)ESHS6 lethal (1) ESHS6 http://flybase.org/reports/FBgn0001685 - gene - - - l(1)ESHS6 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0264997 lncRNA:CR44148 - http://flybase.org/reports/FBgn0264997 non_protein_coding_gene - - - CR44148 - CR44148 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0008641 94Che 94Che http://flybase.org/reports/FBgn0008641 - gene - - - 94Che - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005069 fs(2)OW210 female sterile (2) OW210 http://flybase.org/reports/FBgn0005069 - gene - - - fs(2)OW210 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0013253 E(var)3-7 E(var)3-7 http://flybase.org/reports/FBgn0013253 - gene - - - "E-var(3)7, E(var)3-7" - - 27-Aug-18 DroID_v2018_08 - - - - - - "enhancer of variegation,dominant" FBgn0014104 anon-4Cc anon-4Cc http://flybase.org/reports/FBgn0014104 - gene - - - "T7, anon-4Cc" - - 27-Aug-18 DroID_v2018_08 - - - - - - embryonic stage | 0-3 hr FBgn0060446 l(3)S122407b lethal (3) S122407b http://flybase.org/reports/FBgn0060446 gene - - - "1224/07, l(3)S122407b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal" FBgn0266498 s-167 - http://flybase.org/reports/FBgn0266498 gene - - - s-167 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267600 lncRNA:CR45938 - http://flybase.org/reports/FBgn0267600 non_protein_coding_gene - - - CR45938 - CR45938 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0053806 His3:CG33806 His3:CG33806 http://flybase.org/reports/FBgn0053806 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 nucleosomal DNA binding ; GO:0031492 | inferred from sequence or structural similarity with UniProtKB:P84243 nucleosome assembly ; GO:0006334 | inferred from sequence or structural similarity with UniProtKB:P84243 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with UniProtKB:P84243 "CG33806, His3:CG33806" "IPR000164:Histone H3/CENP-A, IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3" CG33806 27-Aug-18 DroID_v2018_08 "Drer\si:ch1073-429i10.3, Drer\zgc:113984, Drer\zgc:113983, Drer\cenpa, Drer\zgc:173552, Drer\h3f3b.1, Drer\LOC108190747, Drer\si:ch73-36p18.2, Drer\hist2h3c, Drer\h3f3d, Drer\h3f3a, Drer\hist2h3ca1, Drer\si:dkey-23a13.8, Drer\h3f3c, Drer\LOC108190746" "Scer\CSE4, Scer\HHT2, Scer\HHT1" "Cele\his-25, Cele\his-70, Cele\his-69, Cele\his-72, Cele\his-74, Cele\his-9, Cele\his-6, Cele\his-2, Cele\his-55, Cele\his-32, Cele\his-13, Cele\his-27, Cele\his-45, Cele\his-49, Cele\his-42, Cele\his-71, Cele\his-63, Cele\his-17, Cele\his-59" "Xtro\hist2h3d, Xtro\h3f3b, Xtro\LOC100487756, Xtro\cenpa" "Mmus\Hist1h3c, Mmus\Cenpa, Mmus\Hist1h3h, Mmus\Hist1h3i, Mmus\Hist1h3g, Mmus\Hist2h3b, Mmus\Hist1h3d, Mmus\H3f3b, Mmus\H3f3a, Mmus\Hist2h3c1, Mmus\Hist1h3a, Mmus\Hist2h3c2, Mmus\Hist1h3b, Mmus\Hist1h3e, Mmus\Hist1h3f" "Hsap\H3F3C, Hsap\HIST1H3D, Hsap\HIST1H3E, Hsap\HIST1H3A, Hsap\HIST1H3H, Hsap\HIST1H3J, Hsap\HIST1H3C, Hsap\H3F3A, Hsap\HIST1H3F, Hsap\HIST1H3B, Hsap\HIST3H3, Hsap\CENPA, Hsap\HIST2H3A, Hsap\HIST2H3D, Hsap\HIST1H3G, Hsap\HIST2H3C, Hsap\HIST1H3I, Hsap\H3F3B" FBgn0265910 lncRNA:CR44699 - http://flybase.org/reports/FBgn0265910 non_protein_coding_gene - - - "lincRNA.39, CR44699" - CR44699 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039055 Rassf Ras association family member http://flybase.org/reports/FBgn0039055 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781 protein binding ; GO:0005515 | inferred from physical interaction with hpo response to gamma radiation ; GO:0010332 | inferred from mutant phenotype negative regulation of signal transduction ; GO:0009968 | inferred from mutant phenotype regulation of multicellular organism growth ; GO:0040014 | inferred from mutant phenotype - "Rassf, dRASSF, CG4656, dmRASSF, RASSF, dRassf" "IPR000159:Ras-associating (RA) domain, IPR001781:Zinc finger, LIM-type, IPR011524:SARAH domain, IPR029071:Ubiquitin-related domain, IPR033614:C-terminal RASSF family" CG4656 27-Aug-18 DroID_v2018_08 "Drer\mical2a, Drer\rassf6, Drer\mical1, Drer\rassf4, Drer\crip1, Drer\mical3a, Drer\rassf2b, Drer\rassf2a, Drer\mical3b, Drer\rassf3, Drer\mical2b" Scer\ATP14 "Cele\rsf-1, Cele\valv-1, Cele\exc-9" "Xtro\rassf2, Xtro\mical2, Xtro\rassf3, Xtro\rassf4, Xtro\crip1, Xtro\rassf5, Xtro\rassf6, Xtro\rassf1, Xtro\mical3" "Mmus\Rassf6, Mmus\Mical1, Mmus\Rassf5, Mmus\Rassf4, Mmus\Mical2, Mmus\Mical3, Mmus\Rassf2, Mmus\Rassf3, Mmus\Rassf1, Mmus\Crip1" "Hsap\MICAL3, Hsap\MICAL1, Hsap\RASSF1, Hsap\MICAL2, Hsap\RASSF3, Hsap\CRIP1, Hsap\RASSF6, Hsap\RASSF2, Hsap\RASSF4" "viable,radiation sensitive,fertile,small body" wing FBgn0013266 E(var)A1 E(var)A1 http://flybase.org/reports/FBgn0013266 - gene - - - E(var)A1 - - 27-Aug-18 DroID_v2018_08 - - - - - - "enhancer of variegation,dominant" FBgn0266511 s-477 - http://flybase.org/reports/FBgn0266511 gene - - - s-477 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033816 CG4679 - http://flybase.org/reports/FBgn0033816 protein_coding_gene ribosomal small subunit binding ; GO:0043024 | inferred from sequence or structural similarity with UniProtKB:Q96EY7 rRNA binding ; GO:0019843 | inferred from sequence or structural similarity with UniProtKB:Q96EY7 mitochondrial translation ; GO:0032543 | inferred from sequence or structural similarity with UniProtKB:Q96EY7 mitochondrion ; GO:0005739 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q96EY7 "CG4679, RE17985p" "IPR002885:Pentatricopeptide repeat, IPR011990:Tetratricopeptide-like helical domain" CG4679 27-Aug-18 DroID_v2018_08 Drer\ptcd3 - Cele\let-630 Xtro\ptcd3 Mmus\Ptcd3 Hsap\PTCD3 "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0043556 Su(ro[DOM])3023 Su(ro[DOM])3023 http://flybase.org/reports/FBgn0043556 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with ro cellular_component ; GO:0005575 | no biological data available Su(ro[DOM])3023 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0051658 Nnf1b Nnf1b http://flybase.org/reports/FBgn0051658 protein_coding_gene molecular_function ; GO:0003674 | no biological data available mitotic metaphase plate congression ; GO:0007080 | inferred from genetic interaction with Nnf1a chromosome segregation ; GO:0007059 | inferred from genetic interaction with Nnf1a NMS complex ; GO:0031617 | inferred from sequence or structural similarity with HGNC:9112 kinetochore ; GO:0000776 | inferred from direct assay Ndc80 complex ; GO:0031262 | inferred from direct assay "Nnf1b, CG31658, dmNnf1R-1" - CG31658 27-Aug-18 DroID_v2018_08 - - - - - - "mitotic cell cycle defective,visible,partially lethal - majority die,some die during pupal stage" "metaphase,mesothoracic tergum" FBgn0020502 CU31.4 Cible d'Ubx 31.4 http://flybase.org/reports/FBgn0020502 - gene - - - "31.4, CU31.4" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0011629 l(2)T57b4 lethal (2) T57b4 http://flybase.org/reports/FBgn0011629 FBgn0005177 gene - - - l(2)T57b4 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0069205 l(2)46Di lethal (2) 46Di http://flybase.org/reports/FBgn0069205 gene - - - l(2)46Di - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,visible,dominant" wing FBgn0263379 lncRNA:CR43431 - http://flybase.org/reports/FBgn0263379 non_protein_coding_gene - - - CR43431 - CR43431 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0024538 l(3)L1820 lethal (3) L1820 http://flybase.org/reports/FBgn0024538 - gene - - - l(3)L1820 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0085295 CG34266 - http://flybase.org/reports/FBgn0085295 protein_coding_gene - - - CG34266 IPR007970:Protein of unknown function DUF733 CG34266 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001696 l(1)ESHS17 lethal (1) ESHS17 http://flybase.org/reports/FBgn0001696 - gene - - - l(1)ESHS17 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0283657 Tlk Tousled-like kinase http://flybase.org/reports/FBgn0283657 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with HGNC:11841 inferred from sequence or structural similarity with HGNC:11842 inferred from sequence or structural similarity with TAIR:gene:1944622 protein binding ; GO:0005515 | inferred from physical interaction with asf1 protein kinase activity ; GO:0004672 | non-traceable author statement protein kinase activity ; GO:0004672 | inferred from direct assay" "chromatin organization ; GO:0006325 | inferred from genetic interaction with asf1 protein phosphorylation ; GO:0006468 | inferred from direct assay mitotic cell cycle, embryonic ; GO:0045448 | inferred from mutant phenotype positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype heterochromatin organization involved in chromatin silencing ; GO:0070868 | inferred from mutant phenotype regulation of cell cycle ; GO:0051726 | inferred from mutant phenotype histone phosphorylation ; GO:0016572 | inferred from mutant phenotype cell adhesion ; GO:0007155 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype protein autophosphorylation ; GO:0046777 | inferred from direct assay chromosome segregation ; GO:0007059 | inferred from genetic interaction with mars antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement" heterochromatin ; GO:0000792 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay "tlk, Tlk, CG34412, CG32782, CG2829, BcDNA:GH07910, l(1)G0054, CG33219, dtlk, anon-WO03040301.116, anon-WO03040301.114, CG32781, EP1413, EP(X)1413, CG12462, TLK, GH17330, EP(X)1408, BEST:GH17330, EP1408" "IPR017441:Protein kinase, ATP binding site, IPR011009:Protein kinase-like domain, IPR008271:Serine/threonine-protein kinase, active site, IPR000719:Protein kinase domain" CG34412 27-Aug-18 DroID_v2018_08 "Drer\tlk1a, Drer\slc25a12, Drer\tlk2, Drer\tlk1b" "Scer\RTK1, Scer\NPR1, Scer\MPS1, Scer\PRR2, Scer\HRK1" "Cele\T07F12.4, Cele\tlk-1" Xtro\tlk2 "Mmus\Tlk1, Mmus\Tlk2" "Hsap\TLK1, Hsap\TLK2" DRSC22926 IEK 1.810233974 0.126963814 2.051290113 -3.806916791 -2.466977625 0.333336039 FBgn0085621 CG41335 - http://flybase.org/reports/FBgn0085621 protein_coding_gene - - - CG41335 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040723 CG5011 - http://flybase.org/reports/FBgn0040723 protein_coding_gene - - - CG5011 - CG5011 27-Aug-18 DroID_v2018_08 - - - - - Hsap\PHGR1 viable FBgn0026088 CG14818 - http://flybase.org/reports/FBgn0026088 "FBgn0047006, FBgn0047172" protein_coding_gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "CT34631, EG:63B12.12, BcDNA:RH52516, BcDNA:RE09176, CG14818" "IPR005374:Uncharacterised protein family UPF0184, eukaryota, IPR022788:Uncharacterised protein family UPF0184" CG14818 27-Aug-18 DroID_v2018_08 Drer\gb:bc139872 "Scer\TVP15, Scer\NSE5, Scer\MND1" Cele\pdl-1 - "Mmus\Pde6d, Mmus\1110008P14Rik" "Hsap\C9orf16, Hsap\PDE6D" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0030640 CG6294 - http://flybase.org/reports/FBgn0030640 protein_coding_gene metallopeptidase activity ; GO:0008237 | inferred from electronic annotation with InterPro:IPR024079 sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - CG6294 "IPR024079:Metallopeptidase, catalytic domain, IPR021917:Uncharacterised protein family, zinc metallopeptidase-like" CG6294 27-Aug-18 DroID_v2018_08 - Scer\YIL108W - - - - "visible,partially lethal - majority die,some die during pupal stage" "mesothoracic tergum,trichogen cell" FBgn0065780 l(2)SH0444 lethal (2) SH0444 http://flybase.org/reports/FBgn0065780 gene - - - "l(2)SH0444, l(2)SH2 0444" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0001812 l(1)nc1 lethal (1) nc1 http://flybase.org/reports/FBgn0001812 - gene - - - "l(1)1308, l(1)nc1" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0032348 CG4751 - http://flybase.org/reports/FBgn0032348 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG4751, Q9VKJ1" "IPR000555:JAB1/MPN/MOV34 metalloenzyme domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG4751 27-Aug-18 DroID_v2018_08 "Drer\mpnd, Drer\mysm1, Drer\psmd14, Drer\brcc3" Scer\RPN11 - "Xtro\psmd14, Xtro\mpnd, Xtro\mysm1, Xtro\brcc3" "Mmus\Brcc3, Mmus\Mpnd, Mmus\Mysm1, Mmus\Psmd14" "Hsap\BRCC3, Hsap\PSMD14, Hsap\MPND, Hsap\MYSM1" viable FBgn0263328 lncRNA:CR43409 - http://flybase.org/reports/FBgn0263328 non_protein_coding_gene - - - CR43409 - CR43409 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0015901 anon-P1609-III anon-P1609-III http://flybase.org/reports/FBgn0015901 - gene - - - anon-P1609-III - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0082626 S(CycE[JP])3.2 S(CycE[JP])3.2 http://flybase.org/reports/FBgn0082626 gene - - - S(CycE[JP])3.2 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0020534 l(2)k09201 lethal (2) k09201 http://flybase.org/reports/FBgn0020534 - gene - - - "l(2)09201, l(2)k09201" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0052815 CG32815 - http://flybase.org/reports/FBgn0052815 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG18830, CG16994, CG32815" - CG32815 27-Aug-18 DroID_v2018_08 "Drer\zgc:113278, Drer\tram2, Drer\tram1" - Cele\tram-1 "Xtro\tram2, Xtro\tram1" "Mmus\Tram2, Mmus\Tram1, Mmus\Tram1l1" "Hsap\TRAM2, Hsap\TRAM1L1" "viable,fertile" FBgn0003567 su(Hw) suppressor of Hairy wing http://flybase.org/reports/FBgn0003567 FBgn0015225 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9V8P9 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q86B87 chromatin insulator sequence binding ; GO:0043035 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q24478 DNA binding ; GO:0003677 | inferred from mutant phenotype sequence-specific DNA binding ; GO:0043565 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VYX1 "negative regulation of chromatin silencing ; GO:0031936 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from mutant phenotype transcription, DNA-templated ; GO:0006351 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay chromatin ; GO:0000785 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay "CG8573, su(HW), Su(Hw), Su(HW), Su(hw), su(hw), Su[Hw], su(Hw), SU(HW), suHw, SUHW" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG8573 27-Aug-18 DroID_v2018_08 "Drer\LOC101884305, Drer\znf1034" - "Cele\hinf-1, Cele\F47E1.3, Cele\Y111B2A.10, Cele\Y55F3AM.14" - "Mmus\Prdm14, Mmus\Zfp148, Mmus\Gzf1, Mmus\Zfp281" "Hsap\ZNF281, Hsap\PRDM14, Hsap\ZNF740, Hsap\PRDM15, Hsap\ZNF501, Hsap\ZNF148" " embryonic stage -- adult stage , oogenesis stage && adult stage | female " ovary

" embryonic stage -- adult stage , adult stage | female , adult stage | male " "female sterile,wild-type,male sterile,recessive,viable,lethal,heat sensitive,visible,partially lethal - majority die,some die during pupal stage" "cuticle,egg chamber,trichogen cell" FBgn0010119 l(1)2Db lethal (1) 2Db http://flybase.org/reports/FBgn0010119 - gene - - - "l(1)107, l(1)2Db" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0032191 CG5734 - http://flybase.org/reports/FBgn0032191 protein_coding_gene phosphatidylinositol binding ; GO:0035091 | inferred from biological aspect of ancestor with PANTHER:PTN000965695 phosphatidylinositol binding ; GO:0035091 | inferred from sequence or structural similarity with HGNC:14979 "retrograde transport, endosome to plasma membrane ; GO:1990126 | inferred from biological aspect of ancestor with PANTHER:PTN000965695 intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000965695" early endosome ; GO:0005769 | inferred from biological aspect of ancestor with PANTHER:PTN000965695 intracellular membrane-bounded organelle ; GO:0043231 | inferred from sequence or structural similarity with HGNC:14979 "CG5734, DmSNX17" "IPR001683:Phox homologous domain, IPR028666:Sorting nexin-17" CG5734 27-Aug-18 DroID_v2018_08 Drer\snx17 - Cele\snx-17 "Xtro\snx17, Xtro\snx31" "Mmus\Snx17, Mmus\Snx31" "Hsap\SNX17, Hsap\SNX31" viable FBgn0085826 CR41620 - http://flybase.org/reports/FBgn0085826 rRNA_gene - - - CR41620 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0027312 l(1)G0097 lethal (1) G0097 http://flybase.org/reports/FBgn0027312 - gene - - - l(1)G0097 - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0045969 Tabor\gag Tabor element gag http://flybase.org/reports/FBgn0045969 transposable_element_gene - - - "ORF1, Pilgrim\gag, Tabor\gag" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033160 Dhx15 DEAH-box helicase 15 http://flybase.org/reports/FBgn0033160 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR011545 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from sequence or structural similarity with SGD:S000003088 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000433338 RNA helicase activity ; GO:0003724 | inferred from sequence or structural similarity with SGD:S000003088 RNA helicase activity ; GO:0003724 | inferred from sequence or structural similarity "positive regulation of p38MAPK cascade ; GO:1900745 | inferred from genetic interaction with p38a mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000003088 neurogenesis ; GO:0022008 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from biological aspect of ancestor with PANTHER:PTN000434138 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013" precatalytic spliceosome ; GO:0071011 | inferred from direct assay spliceosomal complex ; GO:0005681 | inferred from sequence or structural similarity with SGD:S000003088 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000433338 catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "CG11107, cg11107, clone 1.18, anon-EST:Liang-1.18, Dhx15, DHX15" "IPR001650:Helicase, C-terminal, IPR007502:Helicase-associated domain, IPR011709:Domain of unknown function DUF1605, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR011545:DEAD/DEAH box helicase domain" CG11107 27-Aug-18 DroID_v2018_08 "Drer\dhx16, Drer\dhx33, Drer\dhx15, Drer\zgc:158828, Drer\dhx32a, Drer\dhx38, Drer\dhx8, Drer\dhx32b" "Scer\PRP16, Scer\PRP2, Scer\PRP43, Scer\PRP22" "Cele\mog-1, Cele\let-355, Cele\mog-5, Cele\ddx-15, Cele\mog-4" "Xtro\dhx16, Xtro\dhx38, Xtro\dhx15, Xtro\dhx35, Xtro\dhx33, Xtro\dhx8" "Mmus\Dhx32, Mmus\Dhx35, Mmus\Dhx15, Mmus\Dhx16, Mmus\Dhx8, Mmus\Dhx38, Mmus\Dqx1, Mmus\Dhx33" "Hsap\DHX32, Hsap\DHX8, Hsap\DHX15, Hsap\DHX35, Hsap\DHX38, Hsap\DHX33, Hsap\DHX16, Hsap\DQX1" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0024710 anon-63Eb anon-63Eb http://flybase.org/reports/FBgn0024710 - gene - - - anon-63Eb - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0062628 Mod(var)1038 Mod(var)1038 http://flybase.org/reports/FBgn0062628 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1038, Mod(var)1038" - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation" FBgn0005746 l(1)TK238 lethal (1) TK238 http://flybase.org/reports/FBgn0005746 - gene - - - "l238, l(1)TK238" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0045823 vsg visgun http://flybase.org/reports/FBgn0045823 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | traceable author statement learning or memory ; GO:0007611 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype long-term memory ; GO:0007616 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype regulation of cell proliferation ; GO:0042127 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype somatic ring canal ; GO:0098549 | inferred from direct assay cytoplasmic vesicle ; GO:0031410 | inferred from direct assay female germline ring canal ; GO:0035324 | inferred from direct assay "CG16707, FBgn0045823, GH15083, BEST:GH15083, anon-WO0118547.164, vsg, Vsg" IPR007947:CD164-related protein CG16707 27-Aug-18 DroID_v2018_08 "Drer\cd164l2, Drer\cd164, Drer\tmem123" - Cele\C50F2.7 - "Mmus\Tmem123, Mmus\Cd164l2, Mmus\Cd164" "Hsap\CD164, Hsap\TMEM123, Hsap\CD164L2" "viable,memory defective,chemical sensitive,fertile,melanotic mass phenotype" melanotic mass FBgn0044108 E(rst)C384 E(rst)C384 http://flybase.org/reports/FBgn0044108 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "C384, E(rst)C384" - - 27-Aug-18 DroID_v2018_08 - - - - - - viable eye FBgn0002747 min mini http://flybase.org/reports/FBgn0002747 - gene - - - "mi, min" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263114 CG43371 - http://flybase.org/reports/FBgn0263114 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43371 - CG43371 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0053421 5SrRNA:CR33421 5SrRNA:CR33421 http://flybase.org/reports/FBgn0053421 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33421, 5SrRNA:CR33421" - CR33421 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085620 CG41332 - http://flybase.org/reports/FBgn0085620 protein_coding_gene - - - CG41332 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034861 CG9815 - http://flybase.org/reports/FBgn0034861 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG9815 - CG9815 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible" "chaeta,supernumerary" FBgn0017390 l(1)15Da lethal (1) 15Da http://flybase.org/reports/FBgn0017390 - gene - - - l(1)15Da - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0026337 Su(tor)2-341-39 Su(tor)2-341-39 http://flybase.org/reports/FBgn0026337 - gene - - - Su(tor)2-341-39 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0020324 anon-7H1 anon-7H1 http://flybase.org/reports/FBgn0020324 - gene - - - "7H1, anon-7H1" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038266 CG3610 - http://flybase.org/reports/FBgn0038266 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG3610 - CG3610 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0031778 lncRNA:CR9162 - http://flybase.org/reports/FBgn0031778 non_protein_coding_gene - - - "CG9162, CR9162" - CR9162 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" FBgn0064177 l(1)CB-6411-3 lethal (1) CB-6411-3 http://flybase.org/reports/FBgn0064177 gene - - - l(1)CB-6411-3 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0036713 Mip Myoinhibiting peptide precursor http://flybase.org/reports/FBgn0036713 protein_coding_gene G-protein coupled receptor binding ; GO:0001664 | inferred from physical interaction with SPR neuropeptide hormone activity ; GO:0005184 | non-traceable author statement receptor binding ; GO:0005102 | inferred from direct assay negative regulation of juvenile hormone biosynthetic process ; GO:0045968 | non-traceable author statement negative regulation of eating behavior ; GO:1903999 | inferred from mutant phenotype neuropeptide signaling pathway ; GO:0007218 | non-traceable author statement G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from direct assay neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence model "AstB-1, CG6456, Drm-MIP-5, Drm-MIP-2, Drm-MIP-4, Drm-MIP-3, Drm-MIP-1, Drm-MIP, DAP-B, MIP, Mip, AST-B, mip, Ast-B, AstB, ASB, DmMIP5, DmMIP4, DmMIP3, DmMIP2, DmMIP1, MIP-5, MIP-3, MIP-1, MIP-2, MIP-4" - CG6456 27-Aug-18 DroID_v2018_08 "Drer\inab, Drer\si:ch73-269m14.2, Drer\nefma, Drer\nefla, Drer\nefmb, Drer\viml, Drer\desma, Drer\ngs, Drer\prph, Drer\vim, Drer\LOC567924, Drer\si:dkey-33c12.3, Drer\neflb, Drer\gfap, Drer\zgc:65851, Drer\desmb, Drer\inaa" - "Cele\rec-1, Cele\nlp-8, Cele\ceh-81, Cele\nlp-15, Cele\nlp-38" "Xtro\vim.2, Xtro\des.1, Xtro\des.2, Xtro\ina, Xtro\nefh, Xtro\nefl, Xtro\krt8.2, Xtro\vim, Xtro\nif, Xtro\nefm, Xtro\prph" "Mmus\Ina, Mmus\Des, Mmus\Gfap, Mmus\Vim, Mmus\Svs3b, Mmus\Nefh, Mmus\Svs3a, Mmus\Svs2, Mmus\Prph, Mmus\Nefl, Mmus\Nefm" "Hsap\DES, Hsap\INA, Hsap\PRPH, Hsap\NEFL, Hsap\GFAP, Hsap\NEFH, Hsap\C17orf100, Hsap\VIM, Hsap\PI3" "viable,visible" "chaeta,supernumerary" FBgn0259614 B2032 - http://flybase.org/reports/FBgn0259614 gene - - - B2032 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing vein,wing margin bristle,tarsal segment" FBgn0035000 CG13578 - http://flybase.org/reports/FBgn0035000 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13578 - CG13578 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible" trichogen cell FBgn0020550 fs(2)35Ed fs(2)35Ed http://flybase.org/reports/FBgn0020550 - gene - - - fs(2)35Ed - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0020495 D2 D2 http://flybase.org/reports/FBgn0020495 - gene - - - D2 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0029703 CG12692 - http://flybase.org/reports/FBgn0029703 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12692 IPR011705:BTB/Kelch-associated CG12692 27-Aug-18 DroID_v2018_08 - - Cele\kel-3 - - "Hsap\KLHL31, Hsap\KLHL13, Hsap\KLHL9" viable FBgn0261521 stich1 sticky ch1 http://flybase.org/reports/FBgn0261521 gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR003650 protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 "peripheral nervous system development ; GO:0007422 | traceable author statement regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR003650" - "sticky ch-1, sticky ch1-1, 1437/02, sticky ch, stich1" "IPR003650:Orange domain, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" "neuron,chordotonal organ" FBgn0033564 Pex6 Peroxin 6 http://flybase.org/reports/FBgn0033564 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959, InterPro:IPR003960" peroxisome organization ; GO:0007031 | inferred from mutant phenotype peroxisome organization ; GO:0007031 | inferred from sequence or structural similarity with HGNC:8859 peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:8859 "CG30019, DmCG11919, CG11919, Pex6, DmelPex6, PEX6" "IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR003960:ATPase, AAA-type, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG11919 27-Aug-18 DroID_v2018_08 "Drer\pex6, Drer\hao1" Scer\PEX6 "Cele\prx-1, Cele\F41E6.5, Cele\prx-6" - Mmus\Pex6 Hsap\PEX6 "viable,fertile" FBgn0037972 CG10005 - http://flybase.org/reports/FBgn0037972 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE59626, CG10005" IPR001507:Zona pellucida domain CG10005 27-Aug-18 DroID_v2018_08 - - "Cele\cutl-10, Cele\cutl-20, Cele\cutl-2, Cele\ram-5, Cele\cut-6, Cele\cutl-25, Cele\cutl-16, Cele\cutl-6, Cele\cut-1, Cele\cutl-22, Cele\cutl-13, Cele\cut-4, Cele\cutl-11, Cele\cutl-24, Cele\dpy-1, Cele\cut-3, Cele\cutl-9, Cele\cutl-4, Cele\cutl-14, Cele\cutl-28, Cele\F46G11.6, Cele\cutl-26, Cele\T01D1.8, Cele\cutl-12, Cele\cutl-19, Cele\cutl-3, Cele\cutl-5, Cele\cutl-15, Cele\cut-5, Cele\cutl-7, Cele\cutl-29, Cele\cutl-8, Cele\cutl-1" - - - viable FBgn0036886 CG9300 - http://flybase.org/reports/FBgn0036886 protein_coding_gene - - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012584 CG9300 "IPR012584:NUC205, IPR015943:WD40/YVTN repeat-like-containing domain" CG9300 27-Aug-18 DroID_v2018_08 Drer\nol11 - - - Mmus\Nol11 Hsap\NOL11 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0027864 Ogg1 8-oxoguanine DNA glycosylase http://flybase.org/reports/FBgn0027864 - protein_coding_gene oxidized purine nucleobase lesion DNA N-glycosylase activity ; GO:0008534 | inferred from electronic annotation with InterPro:IPR012904 damaged DNA binding ; GO:0003684 | inferred from electronic annotation with InterPro:IPR012904 DNA N-glycosylase activity ; GO:0019104 | inferred from biological aspect of ancestor with PANTHER:PTN000028425 nucleotide-excision repair ; GO:0006289 | inferred from electronic annotation with InterPro:IPR012904 base-excision repair ; GO:0006284 | inferred from mutant phenotype cellular response to oxidative stress ; GO:0034599 | inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype - "CG1795, dOGG1, BcDNA:LD19945, Ogg1, 1795, dOgg1" "IPR003265:HhH-GPD domain, IPR011257:DNA glycosylase, IPR012904:8-oxoguanine DNA glycosylase, N-terminal, IPR023170:Helix-turn-helix, base-excision DNA repair, C-terminal" CG1795 27-Aug-18 DroID_v2018_08 Drer\ogg1 Scer\OGG1 - Xtro\ogg1 Mmus\Ogg1 Hsap\OGG1 "viable,fertile" FBgn0031851 Aatf Apoptosis antagonizing transcription factor http://flybase.org/reports/FBgn0031851 protein_coding_gene molecular_function ; GO:0003674 | no biological data available neurogenesis ; GO:0022008 | inferred from mutant phenotype negative regulation of programmed cell death ; GO:0043069 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN000399853 oogenesis ; GO:0048477 | inferred from mutant phenotype nucleolus ; GO:0005730 | inferred from direct assay nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q9NY61 "CG11188, anon-WO0118547.190, Aatf, AATF, Che-1, nutmeg" "IPR012617:Apoptosis-antagonizing transcription factor, C-terminal, IPR025160:AATF leucine zipper-containing domain" CG11188 27-Aug-18 DroID_v2018_08 Drer\aatf Scer\BFR2 Cele\Y73E7A.2 Xtro\aatf Mmus\Aatf Hsap\AATF "lethal,cell polarity defective,germline clone,viable,female sterile,partially lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "egg chamber,germline clone,oocyte,centrosome | germline clone,polar follicle cell,supernumerary,embryonic/larval neuroblast,ganglion mother cell" FBgn0025010 E(dpp)66C E(dpp)66C http://flybase.org/reports/FBgn0025010 - gene - - - E(dpp)66C - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0011064 l(1)Q17 lethal (1) Q17 http://flybase.org/reports/FBgn0011064 FBgn0010210 gene - - - l(1)Q17 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0065181 l(3)SH002 lethal (3) SH002 http://flybase.org/reports/FBgn0065181 gene - - - "l(3)SH002, l(2)SH3 002" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0019756 l(1)75B4 lethal (1) 75B4 http://flybase.org/reports/FBgn0019756 - gene - - - l(1)75B4 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0000098 aor abdominal one reduced http://flybase.org/reports/FBgn0000098 - gene - - - aor - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive" abdominal segment 1 FBgn0041720 snRNA:U2:34ABc small nuclear RNA U2 at 34ABc http://flybase.org/reports/FBgn0041720 snRNA_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity" U2 snRNP ; GO:0005686 | inferred from sequence or structural similarity Cajal body ; GO:0015030 | inferred from direct assay "U2:34ABc, U2, dU2, U2 snRNA, U2-34ABc, K6, snRNA:U2, U2snRNA, CR33788, snRNA:U2:34ABc, 34B U2" - CR33788 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065411 l(2)SH1567 lethal (2) SH1567 http://flybase.org/reports/FBgn0065411 gene - - - "l(2)SH1567, l(2)SH2 1567" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0015891 anon-77Fa anon-77Fa http://flybase.org/reports/FBgn0015891 - gene - - - "13a, anon-77Fa" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038170 CG14367 - http://flybase.org/reports/FBgn0038170 protein_coding_gene - cilium assembly ; GO:0060271 | inferred from sequence model - CG14367 "IPR023379:ADP-ribosylation factor-like 2-binding protein, domain" CG14367 27-Aug-18 DroID_v2018_08 Drer\cfap36 - Cele\cfap-36 Xtro\cfap36 Mmus\Cfap36 Hsap\CFAP36 FBgn0031814 retm real-time http://flybase.org/reports/FBgn0031814 protein_coding_gene - transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR009038 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR009038 mitochondrion ; GO:0005739 | inferred from direct assay "CG9528, retm" "IPR001251:CRAL-TRIO lipid binding domain, IPR006797:PRELI/MSF1 domain, IPR009038:GOLD domain, IPR011074:CRAL/TRIO, N-terminal domain" CG9528 27-Aug-18 DroID_v2018_08 "Drer\sec14l7, Drer\ttpal, Drer\sec14l8, Drer\sec14l1, Drer\si:dkey-237i9.1, Drer\rlbp1a, Drer\clvs2, Drer\ttpa" "Scer\SFH5, Scer\SEC14, Scer\YKL091C" "Cele\T23G5.2, Cele\T03F7.7, Cele\ctg-1" "Xtro\clvs2, Xtro\mospd2, Xtro\sec14l3, Xtro\ttpa, Xtro\clvs1, Xtro\sec14l1, Xtro\rlbp1, Xtro\sec14l5, Xtro\ttpal" "Mmus\Sec14l1, Mmus\Sec14l3, Mmus\Rlbp1, Mmus\Clvs2, Mmus\Ttpal, Mmus\Sec14l4, Mmus\Clvs1, Mmus\Sec14l5, Mmus\Ttpa, Mmus\Sec14l2" "Hsap\SEC14L1, Hsap\SEC14L6, Hsap\CLVS2, Hsap\CLVS1, Hsap\TTPAL, Hsap\SEC14L4, Hsap\SEC14L5, Hsap\RLBP1, Hsap\TTPA, Hsap\SEC14L2, Hsap\SEC14L3" viable FBgn0062690 EP1371 EP1371 http://flybase.org/reports/FBgn0062690 gene - - - "EP(X)1371, EP1371" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000836 fs(1)M20 female sterile (1) M20 http://flybase.org/reports/FBgn0000836 - gene - - - fs(1)M20 - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive,lethal,rescuable maternal effect,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "egg,maternal effect" FBgn0266230 lncRNA:CR44925 - http://flybase.org/reports/FBgn0266230 non_protein_coding_gene - - - "CR44925, lincRNA.684" - CR44925 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065784 l(2)SH0438 lethal (2) SH0438 http://flybase.org/reports/FBgn0065784 gene - - - "l(2)SH0438, l(2)SH2 0438" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0022706 Ca-1 Carbonic anhydrase-1 http://flybase.org/reports/FBgn0022706 - gene - - - "CA-1, Ca-1" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266572 ebo ellipsoid body open http://flybase.org/reports/FBgn0266572 protein_coding_gene Ran GTPase binding ; GO:0008536 | inferred from electronic annotation with InterPro:IPR001494 intracellular protein transport ; GO:0006886 | inferred from electronic annotation with InterPro:IPR001494 central complex development ; GO:0048036 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype short-term memory ; GO:0007614 | inferred from mutant phenotype adult walking behavior ; GO:0007628 | traceable author statement flight behavior ; GO:0007629 | inferred from mutant phenotype - "EG:165H7.3, ebo, CG3923, Exp1, Exp6, EBO" "IPR001494:Importin-beta, N-terminal domain, IPR016024:Armadillo-type fold, IPR013598:Exportin-1/Importin-beta-like, IPR011989:Armadillo-like helical" CG3923 27-Aug-18 DroID_v2018_08 "Drer\xpo1b, Drer\xpo6, Drer\xpo1a, Drer\xpo5" "Scer\CRM1, Scer\MSN5" - "Xtro\xpo5, Xtro\xpo6, Xtro\xpo1, Xtro\exd3" "Mmus\Xpo1, Mmus\Xpo6, Mmus\Xpo5" "Hsap\XPO1, Hsap\XPO5, Hsap\XPO6" FBgn0034317 CG14499 - http://flybase.org/reports/FBgn0034317 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from sequence or structural similarity with Lectin-galC1 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG14499, CR14499" "IPR016187:C-type lectin fold, IPR016186:C-type lectin-like/link domain, IPR001304:C-type lectin-like" CG14499 27-Aug-18 DroID_v2018_08 - - Cele\clec-225 - - - FBgn0083315 E(smoDN)1171 Enhancer of smoDN 1171 http://flybase.org/reports/FBgn0083315 gene - - - E(smoDN)1171 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267783 lncRNA:CR46114 - http://flybase.org/reports/FBgn0267783 non_protein_coding_gene - - - CR46114 - CR46114 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0027964 l(3)S145511 lethal (3) S145511 http://flybase.org/reports/FBgn0027964 gene - - - "1455/11, l(3)S145511" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0086661 snoRNA:Psi28S-2566 snoRNA:Psi28S-2566 http://flybase.org/reports/FBgn0086661 snoRNA_gene - - - "snoRNA:269, psi28s-2566, Psi28S-2566(SnoR269), snoRNA:Psi28S-2566, Dm-269, snoR269, CR33686, Psi28S-2566, chr3L:18861298..18861726" - CR33686 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266974 lncRNA:CR45425 - http://flybase.org/reports/FBgn0266974 non_protein_coding_gene - - - CR45425 - CR45425 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036953 CG17145 - http://flybase.org/reports/FBgn0036953 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG17145 IPR002557:Chitin binding domain CG17145 27-Aug-18 DroID_v2018_08 Drer\thbd - "Cele\C39D10.7, Cele\cpg-1, Cele\R02F2.4, Cele\cpg-2" - - Hsap\MATN2 FBgn0011058 l(1)Q11 lethal (1) Q11 http://flybase.org/reports/FBgn0011058 FBgn0010210 gene - - - l(1)Q11 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0066370 btx bellatrix http://flybase.org/reports/FBgn0066370 gene - - - btx - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031446 CG15398 - http://flybase.org/reports/FBgn0031446 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR000814 "DNA-templated transcription, initiation ; GO:0006352 | inferred from electronic annotation with InterPro:IPR000814" - CG15398 IPR000814:TATA-box binding protein CG15398 27-Aug-18 DroID_v2018_08 "Drer\tbp, Drer\tbpl1, Drer\tbpl2" Scer\SPT15 "Cele\tlf-1, Cele\tbp-1" "Xtro\tbpl2, Xtro\tbp, Xtro\tbpl1" "Mmus\Tbp, Mmus\Tbpl2, Mmus\Tbpl1" "Hsap\TBP, Hsap\TBPL1, Hsap\TBPL2" viable FBgn0061175 btl::htl btl::htl http://flybase.org/reports/FBgn0061175 engineered_fusion_gene - - - btl::htl - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265700 lncRNA:CR44507 - http://flybase.org/reports/FBgn0265700 non_protein_coding_gene - - - "lincRNA.966, CR44507" - CR44507 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065984 iab-4-6.s iab-4-6.s http://flybase.org/reports/FBgn0065984 gene - - - "4-6 s, iab-4-6.s" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259545 GG01156 - http://flybase.org/reports/FBgn0259545 gene - - - GG01156 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible mediproboscis FBgn0053920 CG33920 - http://flybase.org/reports/FBgn0053920 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33920 IPR010512:Protein of unknown function DUF1091 CG33920 27-Aug-18 DroID_v2018_08 - - Cele\K12H4.7 - - - FBgn0265500 lncRNA:CR44369 - http://flybase.org/reports/FBgn0265500 non_protein_coding_gene - - - CR44369 - CR44369 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0015353 anon-99Cb anon-99Cb http://flybase.org/reports/FBgn0015353 - gene - - - anon-99Cb - - 27-Aug-18 DroID_v2018_08 - - - - - - embryonic stage -- adult stage FBgn0038578 MED17 Mediator complex subunit 17 http://flybase.org/reports/FBgn0038578 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8MSX2 inferred from physical interaction with UniProtKB:Q9V439 RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from mutant phenotype RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from sequence or structural similarity with HGNC:2375 activating transcription factor binding ; GO:0033613 | inferred from physical interaction with Hsf inferred from physical interaction with Dif transcription coactivator activity ; GO:0003713 | contributes_to inferred from direct assay transcription from RNA polymerase II promoter ; GO:0006366 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs sex comb development ; GO:0045498 | inferred from genetic interaction with Scr cellular process ; GO:0009987 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from direct assay transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:2375 nuclear pericentric heterochromatin ; GO:0031618 | inferred from physical interaction with Su(var)205 inferred from physical interaction with MED26 nucleus ; GO:0005634 | inferred from direct assay mediator complex ; GO:0016592 | inferred from sequence or structural similarity with HGNC:2375 mediator complex ; GO:0016592 | inferred from direct assay "Trap80, Med17, TRAP80, dTRAP80, p70, dTRAP80/SRB4, l(3)s2956, dTrap80, CG7957, MED17" "IPR019313:Mediator complex, subunit Med17" CG7957 27-Aug-18 DroID_v2018_08 Drer\med17 Scer\SRB4 Cele\mdt-17 Xtro\med17 Mmus\Med17 Hsap\MED17 "lethal,recessive,cell lethalcell lethal,somatic clone" embryonic/larval brain DRSC16889 IEK 0.763828301 2.94083354 -3.380947175 -0.475176501 3.150046955 2.289141517 FBgn0067641 trou trou http://flybase.org/reports/FBgn0067641 gene molecular_function ; GO:0003674 | no biological data available bicoid mRNA localization ; GO:0045450 | inferred from mutant phenotype pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available trou - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,female sterile" "egg chamber,germline clone,egg" FBgn0283659 THG tRNA-histidine guanylyltransferase http://flybase.org/reports/FBgn0283659 protein_coding_gene "tRNA guanylyltransferase activity ; GO:0008193 | inferred from electronic annotation with InterPro:IPR007537, InterPro:IPR024956 magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR007537, InterPro:IPR024956" "tRNA modification ; GO:0006400 | inferred from electronic annotation with InterPro:IPR007537, InterPro:IPR024956 neurogenesis ; GO:0022008 | inferred from mutant phenotype" - "CG4103, THG, tRNA-guanylyltransferase, l(2)35Bc, br4, l(2)br4, l(2)br, l(2)br13, l(2)br11, C1, l(2)k08808, BG:DS00929.4" "IPR024956:tRNAHis guanylyltransferase catalytic domain, IPR025845:Thg1 C-terminal domain, IPR007537:tRNAHis guanylyltransferase Thg1" CG4103 27-Aug-18 DroID_v2018_08 Drer\thg1l Scer\THG1 - "Xtro\LOC101733043, Xtro\thg1l" Mmus\Thg1l Hsap\THG1L FBgn0027554 CG8042 - http://flybase.org/reports/FBgn0027554 "FBgn0044624, FBgn0046406" protein_coding_gene - - endomembrane system ; GO:0012505 | inferred from direct assay "BcDNA:GH10229, anon-WO0172774.24, anon-WO0140519.245, CG8042" "IPR001012:UBX domain, IPR012336:Thioredoxin-like fold, IPR029071:Ubiquitin-related domain" CG8042 27-Aug-18 DroID_v2018_08 "Drer\si:ch73-173p19.1, Drer\ubxn4, Drer\ubxn1" "Scer\UBX7, Scer\UBX6" "Cele\ubxn-1, Cele\ubxn-4" "Xtro\ubxn4, Xtro\ubxn1" "Mmus\Ubxn1, Mmus\Ubxn4" "Hsap\UBXN1, Hsap\UBXN4" viable FBgn0026185 rdgG retinal degeneration G http://flybase.org/reports/FBgn0026185 - gene - - - rdgG - - 27-Aug-18 DroID_v2018_08 - - - - - - visual behavior defective "photoreceptor cell,retina" FBgn0028927 CG31834 - http://flybase.org/reports/FBgn0028927 protein_coding_gene - - - "BG:DS00929.16, DS00929.16, CG31834" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0058181 CG40181 - http://flybase.org/reports/FBgn0058181 protein_coding_gene - - - CG40181 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0015261 Moorea Moorea http://flybase.org/reports/FBgn0015261 - region - - - Moorea - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0011436 l(3)j12B4 lethal (3) j12B4 http://flybase.org/reports/FBgn0011436 - gene - - - l(3)j12B4 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0044519 fs(1)124 female sterile (1) 124 http://flybase.org/reports/FBgn0044519 gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(1)124 - - 27-Aug-18 DroID_v2018_08 - - - - - - female sterile "germarium,egg chamber" FBgn0005556 l(3)89Ee lethal (3) 89Ee http://flybase.org/reports/FBgn0005556 "FBgn0002368, FBgn0002439" gene - - - "lrb, lbr, lrB, l(3)rB, l(3)89Ee" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0265048 cv-d crossveinless d http://flybase.org/reports/FBgn0265048 protein_coding_gene "lipid transporter activity ; GO:0005319 | inferred from electronic annotation with InterPro:IPR001747, InterPro:IPR011030, InterPro:IPR015255, InterPro:IPR015816, InterPro:IPR015819 heparan sulfate proteoglycan binding ; GO:0043395 | inferred from direct assay BMP binding ; GO:0036122 | inferred from physical interaction with dpp inferred from physical interaction with gbb coreceptor activity ; GO:0015026 | NOT inferred from direct assay" "lipid transport ; GO:0006869 | inferred from electronic annotation with InterPro:IPR001747, InterPro:IPR011030, InterPro:IPR015255, InterPro:IPR015816, InterPro:IPR015819 imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype positive regulation of BMP signaling pathway ; GO:0030513 | inferred from mutant phenotype" extracellular space ; GO:0005615 | inferred from direct assay "CG31150, cv-d, CG9625, CG9627, CG9622, Cv-d" "IPR001747:Lipid transport protein, N-terminal, IPR011030:Vitellinogen, superhelical, IPR015816:Vitellinogen, beta-sheet N-terminal, IPR015819:Lipid transport protein, beta-sheet shell, IPR001846:von Willebrand factor, type D domain, IPR015255:Vitellinogen, open beta-sheet" CG31150 27-Aug-18 DroID_v2018_08 "Drer\vtg6, Drer\vtg2, Drer\vtg3, Drer\vtg1, Drer\si:dkey-4c23.3, Drer\vtg5, Drer\vtg7, Drer\vtg4" - "Cele\vit-5, Cele\vit-2, Cele\vit-4, Cele\vit-6, Cele\vit-3, Cele\vit-1" - - - "viable,fertile,visible,recessive" "posterior crossvein,wing margin,anterior crossvein" FBgn0013590 l(3)97Df lethal (3) 97Df http://flybase.org/reports/FBgn0013590 - gene - - - l(3)97Df - - 27-Aug-18 DroID_v2018_08 - - - - - - partially lethal - majority die FBgn0067869 Mod(Prat:bw)3-6 Mod(Prat:bw)3-6 http://flybase.org/reports/FBgn0067869 gene - - - "Mod-3-6, Mod(Prat:bw)3-6" - - 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0061109 l(3)S007359 lethal (3) S007359 http://flybase.org/reports/FBgn0061109 gene - - - "0073/59, l(3)S007359" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0033351 AIMP1 aaRS-interacting multifunctional protein 1 http://flybase.org/reports/FBgn0033351 protein_coding_gene tRNA binding ; GO:0000049 | inferred from biological aspect of ancestor with PANTHER:PTN000172473 tRNA aminoacylation for protein translation ; GO:0006418 | inferred from biological aspect of ancestor with PANTHER:PTN000172473 aminoacyl-tRNA synthetase multienzyme complex ; GO:0017101 | inferred from biological aspect of ancestor with PANTHER:PTN000172473 methionyl glutamyl tRNA synthetase complex ; GO:0017102 | inferred from biological aspect of ancestor with PANTHER:PTN000172473 "AIMP1, CG8235" "IPR002547:tRNA-binding domain, IPR012340:Nucleic acid-binding, OB-fold" CG8235 27-Aug-18 DroID_v2018_08 "Drer\aimp1, Drer\yars, Drer\zgc:101853" Scer\ARC1 Cele\mars-1 "Xtro\aimp1, Xtro\yars" "Mmus\Aimp1, Mmus\Yars" "Hsap\AIMP1, Hsap\YARS" FBgn0000818 fs(1)K811 female sterile (1) K811 http://flybase.org/reports/FBgn0000818 - gene - - - fs(1)K811 - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive" dorsal appendage FBgn0010306 mod(r)1 modulator of rudimentary 1 http://flybase.org/reports/FBgn0010306 - gene - - - mod(r)1 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037836 CG14692 - http://flybase.org/reports/FBgn0037836 protein_coding_gene myosin light chain binding ; GO:0032027 | inferred from reviewed computational analysis - - CG14692 "IPR000048:IQ motif, EF-hand binding site, IPR003117:cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain" CG14692 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-116m6.4, Drer\LOC796000, Drer\si:dkeyp-117h8.2, Drer\atf7ip, Drer\pho, Drer\LOC100333206, Drer\rtn1b, Drer\ice1, Drer\si:ch211-242b18.1, Drer\LOC561423, Drer\cgnb" "Scer\RPO21, Scer\SEC16, Scer\NET1, Scer\ESC1" "Cele\F11E6.7, Cele\F19H6.3" "Xtro\kiaa1211, Xtro\rsf1, Xtro\rif1" "Mmus\Rif1, Mmus\Rtn4, Mmus\Atf7ip, Mmus\Cobll1, Mmus\Map4, Mmus\Cobl, Mmus\C530008M17Rik, Mmus\Cgn, Mmus\Polr2a, Mmus\Naca, Mmus\Rsf1" "Hsap\CCDC171, Hsap\RIF1, Hsap\ATF7IP, Hsap\RTN4, Hsap\COBLL1, Hsap\CDKN2AIP, Hsap\RTN3, Hsap\CGN, Hsap\KIAA1211, Hsap\COBL, Hsap\RSF1" viable FBgn0085601 CG41287 - http://flybase.org/reports/FBgn0085601 protein_coding_gene - - - CG41287 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0052855 CG32855 - http://flybase.org/reports/FBgn0052855 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32855 - CG32855 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0259643 B0915 - http://flybase.org/reports/FBgn0259643 gene - - - B0915 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing vein L3,wing" FBgn0069434 Egfr::Tl Egfr::Tl http://flybase.org/reports/FBgn0069434 engineered_fusion_gene - - - Egfr::Tl - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266692 asRNA:CR45182 - http://flybase.org/reports/FBgn0266692 non_protein_coding_gene - - - CR45182 - CR45182 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036258 eIF3l eukaryotic translation initiation factor 3 subunit l http://flybase.org/reports/FBgn0036258 protein_coding_gene translation initiation factor activity ; GO:0003743 | inferred from biological aspect of ancestor with PANTHER:PTN000326403 translation initiation factor activity ; GO:0003743 | contributes_to inferred from sequence or structural similarity with HGNC:18138 translational initiation ; GO:0006413 | inferred from sequence or structural similarity with HGNC:18138 neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype eukaryotic translation initiation factor 3 complex ; GO:0005852 | inferred from sequence or structural similarity with HGNC:18138 cytosol ; GO:0005829 | inferred from direct assay eukaryotic translation initiation factor 3 complex ; GO:0005852 | inferred from biological aspect of ancestor with PANTHER:PTN000326403 "CG5642, eIF3l" "IPR011990:Tetratricopeptide-like helical domain, IPR019382:Translation initiation factor 3 complex subunit L" CG5642 27-Aug-18 DroID_v2018_08 Drer\eif3s6ip - "Cele\C03H5.5, Cele\C17G10.9" Xtro\eif3l Mmus\Eif3l Hsap\EIF3L viable DRSC10530 E -1.060752081 1.141647826 -1.868770931 0.12586034 0.128721837 0.798260958 FBgn0000162 baton baton http://flybase.org/reports/FBgn0000162 - gene - - - baton - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,visible,semidominant" "eye,tergite" FBgn0039666 Diedel Diedel http://flybase.org/reports/FBgn0039666 protein_coding_gene cytokine activity ; GO:0005125 | inferred from mutant phenotype defense response to virus ; GO:0051607 | inferred from mutant phenotype response to bacterium ; GO:0009617 | inferred from expression pattern negative regulation of JAK-STAT cascade ; GO:0046426 | traceable author statement extracellular space ; GO:0005615 | inferred from direct assay "BcDNA:RH38110, Diedel, CG11501, die, diedel" IPR025061:Diedel CG11501 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC14317 K 0.325148812 -0.317737346 0.171962994 0.517218706 -1.5835033 -1.148860884 FBgn0023430 l(3)69ABa lethal (3) 69ABa http://flybase.org/reports/FBgn0023430 - gene - - - l(3)69ABa - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0265951 lncRNA:CR44738 - http://flybase.org/reports/FBgn0265951 non_protein_coding_gene - - - "lincRNA.191, CR44738" - CR44738 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036990 mRpL15 mitochondrial ribosomal protein L15 http://flybase.org/reports/FBgn0036990 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with EMBL:AA128556 mitochondrial translation ; GO:0032543 | traceable author statement translation ; GO:0006412 | inferred from sequence or structural similarity with EMBL:AA128556 mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with EMBL:AA128556 mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement "L15, CG5219, l(3)77CDc, mRpL15" "IPR005749:Ribosomal protein L15, bacterial-type, IPR030878:Ribosomal protein L15, IPR021131:Ribosomal protein L18e/L15P" CG5219 27-Aug-18 DroID_v2018_08 Drer\mrpl15 Scer\MRPL10 Cele\mrpl-15 Xtro\mrpl15 Mmus\Mrpl15 Hsap\MRPL15 "wild-type,lethal - all die before end of larval stage,recessive,some die during larval stage,viable,visible" trichogen cell FBgn0039609 CG14529 - http://flybase.org/reports/FBgn0039609 protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR018497" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR008753, InterPro:IPR018497" - CG14529 "IPR000718:Peptidase M13, IPR008753:Peptidase M13, N-terminal domain, IPR018497:Peptidase M13, C-terminal domain, IPR024079:Metallopeptidase, catalytic domain" CG14529 27-Aug-18 DroID_v2018_08 "Drer\ece2b, Drer\mmel1, Drer\phex, Drer\ece1" - "Cele\nep-16, Cele\nep-26, Cele\nep-13, Cele\nep-9, Cele\nep-7, Cele\nep-10, Cele\nep-21, Cele\nep-3, Cele\nep-6, Cele\nep-19, Cele\nep-20, Cele\nep-18, Cele\nep-24, Cele\nep-8, Cele\nep-17, Cele\nep-5, Cele\nep-23, Cele\nep-12" "Xtro\mmel1, Xtro\ece1, Xtro\ece2, Xtro\ecel1" "Mmus\Ecel1, Mmus\Mme, Mmus\Phex, Mmus\Ece1, Mmus\Mmel1, Mmus\Kel, Mmus\Ece2" "Hsap\KEL, Hsap\MMEL1, Hsap\MME, Hsap\PHEX, Hsap\ECE1, Hsap\ECEL1, Hsap\ECE2" viable FBgn0024910 anon-16Fb anon-16Fb http://flybase.org/reports/FBgn0024910 - gene - - - "F-d, anon-16Fb" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0028225 l(3)S005343 lethal (3) S005343 http://flybase.org/reports/FBgn0028225 gene - - - "0053/43, l(3)S005343" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0015415 l(1)15DFa lethal (1) 15DFa http://flybase.org/reports/FBgn0015415 - gene - - - l(1)15DFa - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0005253 l(3)SG72 lethal (3) SG72 http://flybase.org/reports/FBgn0005253 - gene - - - l(3)SG72 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0005080 fs(2)OW804 female sterile (2) OW804 http://flybase.org/reports/FBgn0005080 - gene - - - fs(2)OW804 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038527 CG14324 - http://flybase.org/reports/FBgn0038527 protein_coding_gene - - - "BcDNA:RE34075, CG14324" - CG14324 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0065964 l(2)SH0023 lethal (2) SH0023 http://flybase.org/reports/FBgn0065964 gene - - - l(2)SH0023 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0013505 l(1)R lethal (1) R http://flybase.org/reports/FBgn0013505 - gene - - - l(1)R - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0013659 ms(2)neo4 ms(2)neo4 http://flybase.org/reports/FBgn0013659 - gene - - - ms(2)neo4 - - 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,male semi-sterile,recessive" FBgn0001032 Fs(3)Bot Female sterile (3) Botond http://flybase.org/reports/FBgn0001032 - gene molecular_function ; GO:0003674 | no biological data available embryo development ending in birth or egg hatching ; GO:0009792 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "Bot, Fs(3)Botond, Fs(3)Sz6, Fs(3)Bot" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" FBgn0265459 Pten::Hsap\PTEN - http://flybase.org/reports/FBgn0265459 engineered_fusion_gene - - - Pten::Hsap\PTEN - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "eye,ommatidium" FBgn0082600 barfly barfly http://flybase.org/reports/FBgn0082600 gene - behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype - "barfly, brf, F48" - - 27-Aug-18 DroID_v2018_08 - - - - - - chemical resistant FBgn0060946 l(3)S037913 lethal (3) S037913 http://flybase.org/reports/FBgn0060946 gene - - - "0379/13, l(3)S037913" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0000639 Fbp1 Fat body protein 1 http://flybase.org/reports/FBgn0000639 - protein_coding_gene protein transporter activity ; GO:0008565 | inferred from sequence or structural similarity with UniProtKB:Q23810 inferred from sequence or structural similarity with protein_id:BAA06161.1 inferred from physical interaction with Lsp1α storage protein import into fat body ; GO:0015032 | inferred from sequence or structural similarity with UniProtKB:Q23810 inferred from sequence or structural similarity with protein_id:BAA06161.1 inferred from physical interaction with Lsp1α lipid particle ; GO:0005811 | inferred from direct assay "Fbp1, CG17285, fbp1, Fbp-1, fbp-1, P1, DmeFBP1, FBP1, LP07910p, FBP-1, FbP1" "IPR005203:Hemocyanin, C-terminal, IPR005204:Hemocyanin, N-terminal, IPR013788:Hemocyanin/hexamerin, IPR014756:Immunoglobulin E-set, IPR008922:Uncharacterised domain, di-copper centre" CG17285 27-Aug-18 DroID_v2018_08 - - "Cele\C49A9.2, Cele\C49A9.3, Cele\F58F9.4" - - - " prepupal stage , larval stage | third instar " "viable,visible" "chaeta,supernumerary" DRSC11166 IE -0.107803186 -2.742804636 -1.812833562 -0.040404357 -0.056758943 0.510452512 FBgn0019757 l(1)75B3 lethal (1) 75B3 http://flybase.org/reports/FBgn0019757 - gene - - - l(1)75B3 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0266886 lncRNA:CR45347 - http://flybase.org/reports/FBgn0266886 non_protein_coding_gene - - - CR45347 - CR45347 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040389 mRpL14 mitochondrial ribosomal protein L14 http://flybase.org/reports/FBgn0040389 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with EMBL:AA642134 translation ; GO:0006412 | inferred from sequence or structural similarity with EMBL:AA642134 mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with EMBL:AA642134 mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement "L14, EG:BACH48C10.6, CG14048, BcDNA:RH18819, mRpL14, mRPL14" IPR000218:Ribosomal protein L14P CG14048 27-Aug-18 DroID_v2018_08 Drer\mrpl14 Scer\MRPL38 Cele\mrpl-14 Xtro\mrpl14 Mmus\Mrpl14 Hsap\MRPL14 "viable,visible" trichogen cell FBgn0261505 CR42653 - http://flybase.org/reports/FBgn0261505 pseudogene_attribute - - - "CR42653, noncoding_9454" - CR42653 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051798 CG31798 - http://flybase.org/reports/FBgn0051798 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon-WO0140519.187, CG31798" IPR011990:Tetratricopeptide-like helical domain CG31798 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0267574 lncRNA:CR45914 - http://flybase.org/reports/FBgn0267574 non_protein_coding_gene - - - CR45914 - CR45914 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0052399 CG32399 - http://flybase.org/reports/FBgn0052399 protein_coding_gene - - - "BcDNA:RH33996, CG32399" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001655 l(1)ds9 lethal (1) discs small 9 http://flybase.org/reports/FBgn0001655 - gene - - - "l(1)d sml-9, l(1)d.sml.-9, l(1)ds9" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal - all die before end of larval stage,some die during larval stage" imaginal disc FBgn0029144 P(3)79D P(3)79D http://flybase.org/reports/FBgn0029144 gene - - - P(3)79D - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0261993 CG42811 - http://flybase.org/reports/FBgn0261993 protein_coding_gene - - - "CG42811, CG18669" IPR006631:Protein of unknown function DM4/12 CG42811 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0015486 l(2)46Cj lethal (2) 46Cj http://flybase.org/reports/FBgn0015486 FBgn0019713 gene - - - "O, 20.10, l(2)46CFo, l(2)46Cj" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" "presumptive embryonic/larval digestive system,presumptive embryonic/larval tracheal system" FBgn0053737 snmRNA:430k snmRNA:430:CR33737 http://flybase.org/reports/FBgn0053737 non_protein_coding_gene - - - "CR33737, snmRNA:430:CR33737" - CR33737 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030292 CG11752 - http://flybase.org/reports/FBgn0030292 protein_coding_gene - - mitochondrial respiratory chain complex I ; GO:0005747 | inferred from electronic annotation with InterPro:IPR026193 "anon-EST:Posey214, BcDNA:RH44935, CG11752" IPR026193:NADH-ubiquinone oxidoreductase flavoprotein 3 CG11752 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile,visible" trichogen cell FBgn0019702 l(2)42Bc lethal (2) 42Bc http://flybase.org/reports/FBgn0019702 - gene - - - "l(2)5CC1, 5CC1, l(2)42Bc" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0005403 l(1)10Bo lethal (1) 10Bo http://flybase.org/reports/FBgn0005403 - gene - - - "l(1)VE328, l(1)10Bo" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" "ovariole,germline clone" FBgn0265600 kay::Dpse\kay - http://flybase.org/reports/FBgn0265600 engineered_fusion_gene - - - kay::Dpse\kay - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0041603 fsco four score http://flybase.org/reports/FBgn0041603 gene molecular_function ; GO:0003674 | no biological data available meiosis I cytokinesis ; GO:0007110 | inferred from mutant phenotype meiosis II cytokinesis ; GO:0007111 | inferred from mutant phenotype actomyosin contractile ring contraction ; GO:0000916 | inferred from mutant phenotype meiotic spindle organization ; GO:0000212 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fsco - - 27-Aug-18 DroID_v2018_08 - - - - - - "meiotic cell cycle defective,male,recessive,cytokinesis defective,mitotic cell cycle defective" "spermatid & nucleus | supernumerary,Nebenkern,spindle & meiotic telophase I | male,contractile ring & meiotic telophase I | male,spindle & meiotic telophase II | male,contractile ring & meiotic telophase II | male,spermatid & nucleus | supernumeraryp25),spindle & meiotic telophase I | malep25),contractile ring & meiotic telophase I | malep25),spindle & meiotic telophase II | malep25),contractile ring & meiotic telophase II | malep25)" FBgn0011454 l(3)neo10 lethal (3) neo10 http://flybase.org/reports/FBgn0011454 - gene - - - l(3)neo10 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0060870 l(3)S047117 lethal (3) S047117 http://flybase.org/reports/FBgn0060870 gene - - - "0471/17, l(3)S047117" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0032726 CG10621 - http://flybase.org/reports/FBgn0032726 protein_coding_gene - - - "BEST:LD26123, anon-WO0140519.13, CG10621" IPR003726:Homocysteine-binding domain CG10621 27-Aug-18 DroID_v2018_08 Drer\zgc:172121 "Scer\SAM4, Scer\YMR321C, Scer\MHT1" "Cele\T13G4.4, Cele\metr-1" Xtro\MGC75760 "Mmus\Mtr, Mmus\Bhmt, Mmus\Bhmt2" "Hsap\MTR, Hsap\BHMT2, Hsap\BHMT" viable FBgn0030431 CG4407 - http://flybase.org/reports/FBgn0030431 protein_coding_gene FMN adenylyltransferase activity ; GO:0003919 | inferred from biological aspect of ancestor with PANTHER:PTN000591373 oxidation-reduction process ; GO:0055114 | inferred from biological aspect of ancestor with PANTHER:PTN000591370 FAD biosynthetic process ; GO:0006747 | inferred from biological aspect of ancestor with PANTHER:PTN000591373 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000591370 "CG4407, Fad1" "IPR002500:Phosphoadenosine phosphosulphate reductase, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold" CG4407 27-Aug-18 DroID_v2018_08 Drer\flad1 "Scer\MET16, Scer\FAD1, Scer\YMR178W" Cele\flad-1 - Mmus\Flad1 Hsap\FLAD1 viable FBgn0040928 CR15345 - http://flybase.org/reports/FBgn0040928 pseudogene_attribute - - - "CG15345, CR15345, BcDNA:RE52922" - CR15345 27-Aug-18 DroID_v2018_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0259410 EP-P - http://flybase.org/reports/FBgn0259410 gene - - - EP-P - - 27-Aug-18 DroID_v2018_08 - - - - - - visible wing FBgn0001548 l(1)16Fb lethal (1) 16Fb http://flybase.org/reports/FBgn0001548 - gene - - - "ME-II, MEII, I[[2]], F-a, l(1)16Fb" - - 27-Aug-18 DroID_v2018_08 - - - - - - "wild-type,lethal,non-rescuable maternal effect,visible,recessive,body color defective,dominant,polyphasic" "gastrula embryo,wing vein,adult cuticle,macrochaeta" FBgn0027184 l(2)60A-I lethal (2) 60A-I http://flybase.org/reports/FBgn0027184 - gene - - - l(2)60A-I - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0086393 BG02169 - http://flybase.org/reports/FBgn0086393 gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - BG02169 - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,smell perception defective" FBgn0004762 l(3)89Cc lethal (3) 89Cc http://flybase.org/reports/FBgn0004762 - gene - - - l(3)89Cc - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0022376 Pt-15 Larval protein-15 http://flybase.org/reports/FBgn0022376 - gene - - - "PT-15, Pt-15" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040345 CG3708 - http://flybase.org/reports/FBgn0040345 protein_coding_gene - nucleosome assembly ; GO:0006334 | inferred from electronic annotation with InterPro:IPR002164 nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR002164 "152685_at, EG:BACR7A4.18, CG3708" IPR002164:Nucleosome assembly protein (NAP) CG3708 27-Aug-18 DroID_v2018_08 "Drer\nap1l1, Drer\nap1l4b, Drer\nap1l4a" Scer\NAP1 Cele\nap-1 "Xtro\nap1l4, Xtro\nap1l1" "Mmus\Nap1l4, Mmus\Nap1l3, Mmus\Nap1l5, Mmus\Nap1l2, Mmus\Nap1l1" "Hsap\NAP1L4, Hsap\NAP1L2, Hsap\NAP1L5, Hsap\NAP1L1, Hsap\NAP1L3" viable FBgn0001431 l(1)7Aa lethal (1) 7Aa http://flybase.org/reports/FBgn0001431 - gene - - - "l(1)jnR1, jnR1, RA62, l(1)inR1, l(1)7Aa" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0038676 CG6026 - http://flybase.org/reports/FBgn0038676 protein_coding_gene voltage-gated potassium channel activity ; GO:0005249 | inferred from biological aspect of ancestor with PANTHER:PTN000025348 regulation of membrane potential ; GO:0042391 | inferred from biological aspect of ancestor with PANTHER:PTN000025348 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000025348 CG6026 - CG6026 27-Aug-18 DroID_v2018_08 - - - - Mmus\Brd4 - "lethal,viable" FBgn0002270 l(3)69Bb lethal (3) 69Bb http://flybase.org/reports/FBgn0002270 - gene - - - "rsg32, l(3)rsg32, l(3)69Bb" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0262986 CG43294 - http://flybase.org/reports/FBgn0262986 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG43294 IPR002557:Chitin binding domain CG43294 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0019933 S(rux)2C S(rux)2C http://flybase.org/reports/FBgn0019933 - gene - - - S(rux)2C - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,mitotic cell cycle defective" FBgn0065434 l(2)SH1478 lethal (2) SH1478 http://flybase.org/reports/FBgn0065434 gene - - - "l(2)SH1478, l(2)SH2 1478" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0039246 CG10845 - http://flybase.org/reports/FBgn0039246 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001752 ATPase activity ; GO:0016887 | NOT inferred from sequence or structural similarity with MGI:MGI:2447072 microtubule binding ; GO:0008017 | inferred from sequence or structural similarity with MGI:MGI:2447072 microtubule motor activity ; GO:0003777 | NOT inferred from sequence or structural similarity with MGI:MGI:2447072 biological_process ; GO:0008150 | no biological data available microtubule-based movement ; GO:0007018 | NOT inferred from sequence or structural similarity with MGI:MGI:2447072 kinesin complex ; GO:0005871 | inferred from sequence or structural similarity with Khc "CG10845, Klp96B, KIF26A/B" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR001752:Kinesin motor domain" CG10845 27-Aug-18 DroID_v2018_08 "Drer\kif3b, Drer\kif5ba, Drer\kif5ab, Drer\kif5c, Drer\kif5bb, Drer\kif3a, Drer\lztfl1, Drer\kif3cb" "Scer\SMY1, Scer\KIP3" Cele\unc-116 "Xtro\kif5c, Xtro\kif3c, Xtro\lztfl1, Xtro\kif3b, Xtro\kif5b, Xtro\kif5a" "Mmus\Lztfl1, Mmus\Kif5a, Mmus\Kif3a, Mmus\Kif3c, Mmus\Kif5b, Mmus\Kif5c, Mmus\Kif3b" "Hsap\KIF5C, Hsap\KIF5A, Hsap\KIF3C, Hsap\LZTFL1, Hsap\KIF5B, Hsap\KIF3B" viable FBgn0053247 Ste:CG33247 Ste:CG33247 http://flybase.org/reports/FBgn0053247 protein_coding_gene protein kinase regulator activity ; GO:0019887 | inferred from mutant phenotype regulation of protein serine/threonine phosphatase activity ; GO:0080163 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay protein kinase CK2 complex ; GO:0005956 | inferred from direct assay "CG32605, CG33247, Ste:CG33247" "IPR000704:Casein kinase II, regulatory subunit, IPR016149:Casein kinase II, regulatory subunit, alpha-helical" CG33247 27-Aug-18 DroID_v2018_08 Drer\csnk2b "Scer\CKB2, Scer\CKB1" Cele\kin-10 Xtro\csnk2b Mmus\Csnk2b Hsap\CSNK2B FBgn0038568 CG14315 - http://flybase.org/reports/FBgn0038568 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14315 - CG14315 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0085771 28SrRNA-Psi:CR40741 28S ribosomal RNA pseudogene:CR40741 http://flybase.org/reports/FBgn0085771 pseudogene_attribute - - - "CR40741, 28SrRNA-Psi:CR40741" - CR40741 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002351 l(3)87Dc lethal (3) 87Dc http://flybase.org/reports/FBgn0002351 - gene - - - "C1, B103, B-103, l(3)B103, l(3)B-103, l(3)87Dc" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0030569 CG9411 - http://flybase.org/reports/FBgn0030569 protein_coding_gene - - - CG9411 - CG9411 27-Aug-18 DroID_v2018_08 - - - - - Hsap\MBD6 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0265820 lncRNA:CR44609 - http://flybase.org/reports/FBgn0265820 non_protein_coding_gene - - - "lincRNA.41, CR44609" - CR44609 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0061510 fsl fusolo http://flybase.org/reports/FBgn0061510 gene - male meiosis chromosome segregation ; GO:0007060 | inferred from mutant phenotype - fsl - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,sterile" "meiosis & nuclear chromosome,anaphase & condensed nuclear chromosomeBK10),telophase & nuclear chromosomeBK10),nuclear chromosomeBK10),nuclear chromosome,kinetochore,microtubule" FBgn0085529 CG40867 - http://flybase.org/reports/FBgn0085529 protein_coding_gene - - - CG40867 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034879 Rrp4 Rrp4 http://flybase.org/reports/FBgn0034879 protein_coding_gene RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000481223 "nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' ; GO:0034427 | inferred from biological aspect of ancestor with PANTHER:PTN000481224 CUT catabolic process ; GO:0071034 | inferred from biological aspect of ancestor with PANTHER:PTN000481223 polyadenylation-dependent snoRNA 3'-end processing ; GO:0071051 | inferred from biological aspect of ancestor with PANTHER:PTN000481223 nuclear polyadenylation-dependent rRNA catabolic process ; GO:0071035 | inferred from biological aspect of ancestor with PANTHER:PTN000481224 nuclear polyadenylation-dependent tRNA catabolic process ; GO:0071038 | inferred from biological aspect of ancestor with PANTHER:PTN000481223 defense response to virus ; GO:0051607 | inferred from mutant phenotype exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000467 | inferred from biological aspect of ancestor with PANTHER:PTN000481223 nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription ; GO:0071049 | inferred from biological aspect of ancestor with PANTHER:PTN000481224 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay ; GO:0043928 | inferred from biological aspect of ancestor with PANTHER:PTN000481223 regulation of gene expression ; GO:0010468 | inferred from mutant phenotype U4 snRNA 3'-end processing ; GO:0034475 | inferred from biological aspect of ancestor with PANTHER:PTN000481223" nuclear lamina ; GO:0005652 | inferred from direct assay exosome (RNase complex) ; GO:0000178 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay nuclear exosome (RNase complex) ; GO:0000176 | inferred from sequence or structural similarity with SGD:S000001111 inferred from direct assay cytoplasmic exosome (RNase complex) ; GO:0000177 | inferred from biological aspect of ancestor with PANTHER:PTN000481224 "RRP4, CG3931, dRrp4, Rrp4, rrp4" "IPR025721:Exosome complex component, N-terminal domain, IPR012340:Nucleic acid-binding, OB-fold, IPR004088:K Homology domain, type 1, IPR026699:Exosome complex RNA-binding protein 1/RRP40/RRP4" CG3931 27-Aug-18 DroID_v2018_08 Drer\exosc2 Scer\RRP4 Cele\exos-2 Xtro\exosc2 Mmus\Exosc2 Hsap\EXOSC2 "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0266245 lncRNA:CR44940 - http://flybase.org/reports/FBgn0266245 non_protein_coding_gene - - - "CR44940, lincRNA.747" - CR44940 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0062569 Mod(var)E1672 Mod(var)E1672 http://flybase.org/reports/FBgn0062569 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "E1672, Mod(var)E1672" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive,enhancer of variegation,non-enhancer of variegation,non-suppressor of variegation,dominant" FBgn0002907 mus310 mutagen-sensitive 310 http://flybase.org/reports/FBgn0002907 - gene - - - "mus(3)310, mus310" - - 27-Aug-18 DroID_v2018_08 - - - - - - "DNA repair defective,radiation sensitive,chemical sensitive,recessive" FBgn0003676 CCT1 Chaperonin containing TCP1 subunit 1 http://flybase.org/reports/FBgn0003676 FBgn0043836 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002194, InterPro:IPR002423, InterPro:IPR012715 unfolded protein binding ; GO:0051082 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 protein binding involved in protein folding ; GO:0044183 | inferred from biological aspect of ancestor with PANTHER:PTN000143677" chaperone-mediated protein folding ; GO:0061077 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 'de novo' protein folding ; GO:0006458 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 phagocytosis ; GO:0006909 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay chaperonin-containing T-complex ; GO:0005832 | inferred from biological aspect of ancestor with PANTHER:PTN000144020 "T-cpl, gh05123, BEST:GH05123, Tcp-1, CG5374, T-cp1, tcp1, Tcp1, Tcp1-like, TCPA_DROME, CCT1, TCP-1alpha, Tcp1-alpha, TCP1alpha, T-CP1, TCP1-alpha, cct1" "IPR017998:Chaperone tailless complex polypeptide 1 (TCP-1), IPR002194:Chaperonin TCP-1, conserved site, IPR002423:Chaperonin Cpn60/TCP-1 family, IPR012715:T-complex protein 1, alpha subunit, IPR027409:GroEL-like apical domain, IPR027413:GroEL-like equatorial domain" CG5374 27-Aug-18 DroID_v2018_08 "Drer\mkks, Drer\cct7, Drer\bbs10, Drer\tcp1" Scer\TCP1 Cele\cct-1 "Xtro\cct7, Xtro\tcp1" "Mmus\Bbs10, Mmus\Mkks, Mmus\Cct7, Mmus\Tcp1" "Hsap\CCT7, Hsap\BBS10, Hsap\MKKS, Hsap\TCP1" "lethal - all die before end of pupal stage,some die during pupal stage" DRSC16877 E 1.426228757 -0.613398535 3.027004188 -0.751635585 -0.135714501 -0.566715079 FBgn0040793 CG7630 - http://flybase.org/reports/FBgn0040793 protein_coding_gene - - lipid particle ; GO:0005811 | inferred from direct assay "anon-EST:Posey228, anon-EST:Posey153, BcDNA:RH19679, CG7630" IPR031973:Deltamethrin resistance protein prag01 CG7630 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible" trichogen cell DRSC10895 I -1.446533134 -1.849959914 -1.306958193 -0.683119007 -0.341451225 1.495704406 FBgn0001389 l(1)2Bu lethal (1) 2Bu http://flybase.org/reports/FBgn0001389 - gene - - - "l(1)10-153-2, 10-153-2, l(1)2Bu" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0052151 CG32151 - http://flybase.org/reports/FBgn0052151 protein_coding_gene - - - CG32151 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0011135 l(1)Q210 lethal (1) Q210 http://flybase.org/reports/FBgn0011135 FBgn0010210 gene - - - l(1)Q210 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0265106 lncRNA:CR44208 - http://flybase.org/reports/FBgn0265106 non_protein_coding_gene - - - CR44208 - CR44208 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0053153 CG33153 - http://flybase.org/reports/FBgn0053153 protein_coding_gene - - - CG33153 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037464 CG1988 - http://flybase.org/reports/FBgn0037464 protein_coding_gene - - - CG1988 - CG1988 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" FBgn0265727 lncRNA:CR44534 - http://flybase.org/reports/FBgn0265727 non_protein_coding_gene - - - "CR44534, lincRNA.972" - CR44534 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263887 l(3)D7 - http://flybase.org/reports/FBgn0263887 gene - - - l(3)D7 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,cell cycle defective,somatic clone" "embryonic/larval brain,somatic clone,embryonic/larval neuroblast" FBgn0011095 l(1)Q55 lethal (1) Q55 http://flybase.org/reports/FBgn0011095 FBgn0010210 gene - - - l(1)Q55 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0001654 l(1)ds8 lethal (1) discs small 8 http://flybase.org/reports/FBgn0001654 - gene - - - "l(1)d sml-8, l(1)d.sml.-8, l(1)ds8" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" imaginal disc FBgn0002249 l(3)68Dc lethal (3) 68Dc http://flybase.org/reports/FBgn0002249 - gene - - - "rsg10, l(3)rsg10, l(3)68Dc" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0053468 CG33468 - http://flybase.org/reports/FBgn0053468 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33468 - CG33468 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0267865 lncRNA:CR46153 - http://flybase.org/reports/FBgn0267865 non_protein_coding_gene - - - CR46153 - CR46153 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0014845 E(var)2-88 Enhancer of variegation 2-88 http://flybase.org/reports/FBgn0014845 - gene - - - E(var)2-88 - - 27-Aug-18 DroID_v2018_08 - - - - - - enhancer of variegation FBgn0250826 CG34160 - http://flybase.org/reports/FBgn0250826 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG34160, NEST:bs34b09" - CG34160 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267494 Mst77Y-8Psi Male-specific pseudogene 77Y 8 http://flybase.org/reports/FBgn0267494 pseudogene_attribute - - - "CR45774, Mst77Y-8Psi, Mst77Y-8" - CR45774 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065967 l(2)SH0008 lethal (2) SH0008 http://flybase.org/reports/FBgn0065967 gene - - - "l(2)SH0008, l(2)SH2 0008" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0015546 spel1 spellchecker1 http://flybase.org/reports/FBgn0015546 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000432, InterPro:IPR007695, InterPro:IPR007696, InterPro:IPR007860, InterPro:IPR007861, InterPro:IPR011184 mismatched DNA binding ; GO:0030983 | inferred from electronic annotation with InterPro:IPR000432, InterPro:IPR007695, InterPro:IPR007696, InterPro:IPR007860, InterPro:IPR007861, InterPro:IPR011184 DNA binding ; GO:0003677 | non-traceable author statement" mismatch repair ; GO:0006298 | inferred from mutant phenotype postreplication repair ; GO:0006301 | inferred from sequence or structural similarity with UniProtKB:P43246 maintenance of DNA repeat elements ; GO:0043570 | inferred from mutant phenotype interstrand cross-link repair ; GO:0036297 | inferred from mutant phenotype inferred from genetic interaction with Fancd2 mismatch repair complex ; GO:0032300 | inferred from electronic annotation with InterPro:IPR032642 nucleus ; GO:0005634 | non-traceable author statement "spel, CG4215, Msh2, BG:DS01068.9, SPEL1, spel-1, spel1" "IPR000432:DNA mismatch repair protein MutS, C-terminal, IPR007695:DNA mismatch repair protein MutS-like, N-terminal, IPR007696:DNA mismatch repair protein MutS, core, IPR007860:DNA mismatch repair protein MutS, connector domain, IPR007861:DNA mismatch repair protein MutS, clamp, IPR011184:DNA mismatch repair MutS, IPR016151:DNA mismatch repair protein MutS, N-terminal, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR032642:DNA mismatch repair protein Msh2" CG4215 27-Aug-18 DroID_v2018_08 Drer\msh2 Scer\MSH2 Cele\msh-2 Xtro\msh2 Mmus\Msh2 Hsap\MSH2 viable DRSC03617 E 1.183911735 -0.362520525 -1.831481868 0.367864972 -0.135616213 -0.117266577 FBgn0013258 E(var)35 E(var)35 http://flybase.org/reports/FBgn0013258 - gene - - - E(var)35 - - 27-Aug-18 DroID_v2018_08 - - - - - - "enhancer of variegation,dominant" FBgn0020877 anon-A8 anon-A8 http://flybase.org/reports/FBgn0020877 - gene - - - "2-A8, anon-A8" - - 27-Aug-18 DroID_v2018_08 - - - - - - "fertile,chemical sensitive,recessive" FBgn0020832 l(2)PW "Pullman, Washington" http://flybase.org/reports/FBgn0020832 - gene - - - l(2)PW - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0014329 l(3)ry74 lethal (3) ry74 http://flybase.org/reports/FBgn0014329 - gene - - - l(3)ry74 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0015024 CkIalpha Casein kinase Ialpha http://flybase.org/reports/FBgn0015024 "FBgn0029043, FBgn0066807, FBgn0066808" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:O16844 protein kinase activity ; GO:0004672 | inferred from direct assay protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity" negative regulation of smoothened signaling pathway ; GO:0045879 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 negative regulation of canonical Wnt signaling pathway ; GO:0090090 | inferred by curator from GO:0032436 inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement phagocytosis ; GO:0006909 | inferred from mutant phenotype regulation of proteolysis ; GO:0030162 | traceable author statement regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype positive regulation of protein catabolic process ; GO:0045732 | inferred from mutant phenotype peptidyl-serine phosphorylation ; GO:0018105 | inferred from biological aspect of ancestor with PANTHER:PTN000225966 protein catabolic process ; GO:0030163 | non-traceable author statement protein phosphorylation ; GO:0006468 | inferred from direct assay cell morphogenesis ; GO:0000902 | inferred from mutant phenotype DNA repair ; GO:0006281 | inferred from direct assay regulation of Wnt signaling pathway ; GO:0030111 | inferred from mutant phenotype positive regulation of proteasomal ubiquitin-dependent protein catabolic process ; GO:0032436 | inferred from mutant phenotype positive regulation of proteasomal ubiquitin-dependent protein catabolic process ; GO:0032436 | inferred from direct assay neurogenesis ; GO:0022008 | inferred from mutant phenotype beta-catenin destruction complex ; GO:0030877 | inferred from sequence or structural similarity with UniProtKB:P48729 nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CK1, CK1alpha, CKIalpha, CKI, CK1a, CkIa, CKIa, CG2028, CK I, dmckI, dmCK1, CkIalpha, l(1)G0492, anon-WO03040301.95, anon-WO03040301.93, ck1alpha, CKI alpha, ck1a, PKA-C, CkI alpha, Ck1alpha" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG2028 27-Aug-18 DroID_v2018_08 "Drer\ttbk1b, Drer\csnk1db, Drer\vrk1, Drer\csnk1da, Drer\ttbk1a, Drer\ttbk2b, Drer\vrk2, Drer\csnk1e, Drer\csnk1a1, Drer\vrk3" "Scer\YCK1, Scer\HRR25, Scer\YCK3, Scer\YCK2" "Cele\Y39G8C.2, Cele\Y111B2A.27, Cele\K09E4.1, Cele\kin-20, Cele\kin-19" "Xtro\vrk3, Xtro\csnk1a1, Xtro\ttbk2, Xtro\csnk1d, Xtro\vrk2, Xtro\vrk1, Xtro\csnk1e" "Mmus\Csnk1e, Mmus\Vrk3, Mmus\Vrk2, Mmus\Ttbk1, Mmus\Vrk1, Mmus\Csnk1d, Mmus\Ttbk2, Mmus\Csnk1a1" "Hsap\VRK1, Hsap\TTBK2, Hsap\CSNK1A1, Hsap\LOC400927-CSNK1E, Hsap\CSNK1E, Hsap\CSNK1A1L, Hsap\VRK3, Hsap\CSNK1D, Hsap\TTBK1, Hsap\VRK2" "visible,somatic clone,lethal,behavior defective,recessive,female sterile,partially lethal - majority die,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "eye,somatic clone,eye disc,wing,embryonic/first instar larval cuticle,ventral nerve cord commissure,longitudinal connective,embryonic epidermis,wing margin bristle,ectopic,embryonic/larval neuroblast,ganglion mother cell,synapse,neuromuscular junction" DRSC22609 K 0.226418346 0.061498999 -0.219256744 1.367663992 1.505405909 1.157408614 FBgn0005717 l(1)TK123 lethal (1) TK123 http://flybase.org/reports/FBgn0005717 - gene - - - "l123, l(1)TK123" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0035762 Rint1 RAD50 interactor 1 http://flybase.org/reports/FBgn0035762 protein_coding_gene - cleavage furrow ingression ; GO:0036090 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype Golgi vesicle transport ; GO:0048193 | inferred from sequence or structural similarity with SGD:S000003113 Golgi organization ; GO:0007030 | inferred from mutant phenotype male meiosis cytokinesis ; GO:0007112 | inferred from mutant phenotype endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with SGD:S000003113 Dsl1/NZR complex ; GO:0070939 | inferred from sequence or structural similarity with SGD:S000003113 "CG8605, Tip20, Rint-1, Rint1, rint1" IPR007528:RINT-1/Tip20 CG8605 27-Aug-18 DroID_v2018_08 Drer\rint1 Scer\TIP20 Cele\F36D1.6 Xtro\rint1 Mmus\Rint1 Hsap\RINT1 "cytokinesis defective,lethal,neuroanatomy defective,body color defective" "Golgi stackbam.THsimVP16,spermatid | third instar larval stage,Nebenkern,contractile ringbam.THsimVP16,spindlebam.THsimVP16,cleavage furrowbam.THsimVP16,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0264504 asRNA:CR43903 - http://flybase.org/reports/FBgn0264504 non_protein_coding_gene - - - CR43903 - CR43903 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000763 fs(1)A543 female sterile (1) A543 http://flybase.org/reports/FBgn0000763 - gene - - - fs(1)A543 - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive,heat sensitive" "wing,female reproductive system" FBgn0085360 CG34331 - http://flybase.org/reports/FBgn0085360 protein_coding_gene - - - CG34331 - CG34331 27-Aug-18 DroID_v2018_08 - - - - - - "viable,body color defective" mesothoracic tergum FBgn0060987 l(3)S028102b lethal (3) S028102b http://flybase.org/reports/FBgn0060987 gene - - - "0281/02, l(3)S028102b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0262534 CG43088 - http://flybase.org/reports/FBgn0262534 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43088, MB8.chrX.pasa.104, MB8.chrX.pasa.104-MIP02663" IPR027806:Harbinger transposase-derived nuclease domain CG43088 27-Aug-18 DroID_v2018_08 "Drer\LOC101887042, Drer\si:dkey-121j17.6, Drer\zmp:0000000634, Drer\LOC101883368, Drer\harbi1, Drer\zgc:162945, Drer\zgc:194221, Drer\LOC569097, Drer\si:dkey-197c15.6, Drer\zgc:113227, Drer\LOC100005423, Drer\LOC103911715, Drer\LOC101882290" - - Xtro\LOC100127800 Mmus\Harbi1 Hsap\HARBI1 FBgn0051545 CG31545 - http://flybase.org/reports/FBgn0051545 protein_coding_gene - - - CG31545 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085714 CG41592 - http://flybase.org/reports/FBgn0085714 protein_coding_gene - - - CG41592 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001130 Gpt Glutamate pyruvate transaminase http://flybase.org/reports/FBgn0001130 - gene - - - "GPT, Gpt" - - 27-Aug-18 DroID_v2018_08 - - - - - - electrophoretic variant FBgn0034480 CG16898 - http://flybase.org/reports/FBgn0034480 protein_coding_gene - - - CG16898 "IPR015897:CHK kinase-like, IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain" CG16898 27-Aug-18 DroID_v2018_08 - - "Cele\F59B1.8, Cele\Y11D7A.8, Cele\F58B4.5, Cele\H37A05.2, Cele\dhs-27, Cele\D1044.1, Cele\Y45G12C.4, Cele\C29F7.2, Cele\T16G1.5, Cele\F59B1.10, Cele\E02C12.9, Cele\nhr-246, Cele\F56A4.5, Cele\F49C12.7, Cele\H06H21.8, Cele\E02C12.8, Cele\E02C12.6, Cele\T16G1.6, Cele\C18B10.6, Cele\E02C12.10, Cele\C29F7.1" - - - viable FBgn0019683 mng mango http://flybase.org/reports/FBgn0019683 - gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with N cellular_component ; GO:0005575 | no biological data available mng - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0023154 Su(mg)2-5 Suppressor of modifier of gypsy 2-5 http://flybase.org/reports/FBgn0023154 - gene - - - Su(mg)2-5 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0010557 l(2)03832a lethal (2) 03832a http://flybase.org/reports/FBgn0010557 - gene - - - "l(2)03832, l(2)03832a" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0021988 l(2)k09624 lethal (2) k09624 http://flybase.org/reports/FBgn0021988 - gene - - - l(2)k09624 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0259330 C371 - http://flybase.org/reports/FBgn0259330 gene - - - C371 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing,wing vein" FBgn0260381 GSd439 - http://flybase.org/reports/FBgn0260381 gene - - - GSd439 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve,segmental nerve" FBgn0034547 CG12485 - http://flybase.org/reports/FBgn0034547 protein_coding_gene - - - CG12485 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0044491 DTD46.6 DTD46.6 http://flybase.org/reports/FBgn0044491 gene - - - DTD46.6 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265855 lncRNA:CR44644 - http://flybase.org/reports/FBgn0265855 non_protein_coding_gene - - - CR44644 - CR44644 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0024305 SS3-6 Suppressor of GMR-sina 3-6 http://flybase.org/reports/FBgn0024305 - gene molecular_function ; GO:0003674 | no biological data available rhabdomere development ; GO:0042052 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available SS3-6 - - 27-Aug-18 DroID_v2018_08 - - - - - - "rhabdomere,somatic clone" FBgn0265638 lncRNA:CR44445 - http://flybase.org/reports/FBgn0265638 non_protein_coding_gene - - - "CR44445, lincRNA.264" - CR44445 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0029907 Atx-1 Ataxin 1 http://flybase.org/reports/FBgn0029907 protein_coding_gene "RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR003652, InterPro:IPR013723" imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype photoreceptor cell maintenance ; GO:0045494 | inferred from mutant phenotype - "dAtx-1, CG4547, Atx-1" "IPR003652:Ataxin, AXH domain" CG4547 27-Aug-18 DroID_v2018_08 "Drer\atxn1l, Drer\atxn1a, Drer\LOC101886356, Drer\zmp:0000000926, Drer\atxn1b" - Cele\K04F10.1 "Xtro\atxn1, Xtro\atxn1l" "Mmus\Atxn1l, Mmus\Atxn1" "Hsap\ATXN1, Hsap\ATXN1L" "viable,fertile,neuroanatomy defective" "eye,eye photoreceptor cell,wing vein,ectopic,interommatidial bristle,ommatidium,rhabdomere of eye photoreceptor cell,heat sensitive,wing,wing margin bristle,metathoracic bristle,mesothoracic bristle" FBgn0267179 lncRNA:CR45619 - http://flybase.org/reports/FBgn0267179 non_protein_coding_gene - - - CR45619 - CR45619 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0021949 l(2)k10411 lethal (2) k10411 http://flybase.org/reports/FBgn0021949 - gene - - - l(2)k10411 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0026417 Hus1-like Hus1-like http://flybase.org/reports/FBgn0026417 - protein_coding_gene - meiotic DNA integrity checkpoint ; GO:0044778 | inferred from mutant phenotype mitotic DNA replication checkpoint ; GO:0033314 | inferred from biological aspect of ancestor with PANTHER:PTN000307391 double-strand break repair via homologous recombination ; GO:0000724 | inferred from biological aspect of ancestor with PANTHER:PTN000307391 mitotic DNA damage checkpoint ; GO:0044773 | inferred from mutant phenotype intra-S DNA damage checkpoint ; GO:0031573 | inferred from biological aspect of ancestor with PANTHER:PTN000307391 female pronucleus assembly ; GO:0035038 | inferred from mutant phenotype nucleotide-excision repair ; GO:0006289 | inferred from biological aspect of ancestor with PANTHER:PTN000307391 nucleolus ; GO:0005730 | inferred from electronic annotation with InterPro:IPR016580 cytoplasm ; GO:0005737 | inferred from direct assay checkpoint clamp complex ; GO:0030896 | inferred from direct assay site of double-strand break ; GO:0035861 | inferred from biological aspect of ancestor with PANTHER:PTN000307391 "Hus1-like, Hus1, CG2525, hus1, DmHus1, Hus-1" "IPR007150:Checkpoint protein Hus1/Mec3, IPR016580:Cell cycle checkpoint, Hus1" CG2525 27-Aug-18 DroID_v2018_08 "Drer\zgc:162895, Drer\oraov1" Scer\MEC3 Cele\hus-1 Xtro\hus1 "Mmus\Oraov1, Mmus\Hus1, Mmus\Hus1b" "Hsap\ORAOV1, Hsap\HUS1, Hsap\HUS1B" "viable,fertile,female sterile,radiation resistant,chemical sensitive,planar polarity defective" "wing,posterior compartment,nucleus110),egg,nucleus,oocyte" FBgn0040797 CG13066 - http://flybase.org/reports/FBgn0040797 protein_coding_gene - - - CG13066 - CG13066 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0260781 10-Feb - http://flybase.org/reports/FBgn0260781 gene - - - 10-Feb - - 27-Aug-18 DroID_v2018_08 - - - - - - chemical sensitive FBgn0001224 Hsp23 Heat shock protein 23 http://flybase.org/reports/FBgn0001224 - protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with lwr unfolded protein binding ; GO:0051082 | inferred from sequence model unfolded protein binding ; GO:0051082 | inferred from direct assay actin binding ; GO:0003779 | inferred from sequence or structural similarity response to hypoxia ; GO:0001666 | inferred from expression pattern inferred from mutant phenotype chaperone-mediated protein folding ; GO:0061077 | inferred from direct assay cold acclimation ; GO:0009631 | inferred from expression pattern response to heat ; GO:0009408 | inferred from direct assay protein refolding ; GO:0042026 | inferred from direct assay chaperone-mediated protein folding ; GO:0061077 | inferred from sequence model microtubule associated complex ; GO:0005875 | inferred from direct assay "Dmel20.6, Hsp23, CG4463, hsp23, HSP23/IAP, DmHsp23, hsp23/22, hsp 23K, hsp 22K, 23, hsp 23, Hsp-23, HSP23, small hsp locus 67B, DmHSP23" "IPR001436:Alpha crystallin/Heat shock protein, IPR002068:Alpha crystallin/Hsp20 domain, IPR008978:HSP20-like chaperone, IPR031107:Small heat shock protein HSP20" CG4463 27-Aug-18 DroID_v2018_08 "Drer\hspb7, Drer\si:dkey-1k23.3, Drer\cryaa, Drer\hspb6, Drer\cryaba, Drer\hspb8, Drer\hspb3, Drer\hspb15, Drer\hspb12, Drer\hspb11, Drer\hspb1, Drer\hspb9, Drer\cryabb, Drer\hspb2" - "Cele\hsp-16.2, Cele\hsp-16.1, Cele\hsp-17, Cele\F08H9.3, Cele\hsp-12.1, Cele\F08H9.4, Cele\hsp-16.49, Cele\hsp-16.48, Cele\hsp-12.3, Cele\ZK1128.7, Cele\hsp-43, Cele\hsp-12.2, Cele\hsp-16.41, Cele\hsp-16.11, Cele\hsp-12.6, Cele\Y55F3BR.6, Cele\sip-1" "Xtro\cryab, Xtro\hspb2, Xtro\hsp30e, Xtro\hspb3, Xtro\uqcrh, Xtro\hsp30d, Xtro\hspb8, Xtro\hspb1, Xtro\hspb6, Xtro\cryaa" "Mmus\Hspb2, Mmus\Hspb6, Mmus\Hspb7, Mmus\Cryab, Mmus\Hspb1, Mmus\Hspb3, Mmus\Hspb8, Mmus\Hspb9, Mmus\Cryaa" "Hsap\HSPB8, Hsap\HSPB7, Hsap\HSPB6, Hsap\HSPB1, Hsap\HSPB9, Hsap\CRYAB, Hsap\CRYAA, Hsap\LOC102724652, Hsap\HSPB2, Hsap\HSPB3" " larval stage | first instar , larval stage , pupal stage | early , prepupal stage , embryonic stage | early " organism

" larval stage | third instar , pupal stage , embryonic stage " "viable,cold stress response defective" "embryonic/larval heart | P-stage,mitochondrion | P-stage,sarcomere | P-stage" FBgn0043476 l(3)66EFj lethal (3) 66EFj http://flybase.org/reports/FBgn0043476 gene - - - l(3)66EFj - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0050106 CCHa1-R CCHamide-1 receptor http://flybase.org/reports/FBgn0050106 protein_coding_gene neuropeptide receptor activity ; GO:0008188 | inferred from sequence model neuropeptide receptor activity ; GO:0008188 | inferred from direct assay allatostatin receptor activity ; GO:0008261 | inferred from direct assay allatostatin receptor activity ; GO:0008261 | NOT inferred from direct assay G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from direct assay "CG14484, CG18192, CG30106, CCHa1-R, CCHa1r, CCHamide1r" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR001556:Bombesin receptor-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG30106 27-Aug-18 DroID_v2018_08 "Drer\ednrba, Drer\si:ch211-119o8.4, Drer\grpr, Drer\ednrab, Drer\ednrbb, Drer\gpr37a, Drer\nmbr, Drer\gpr37b, Drer\si:dkey-42l23.4, Drer\gpr37l1a, Drer\ednraa, Drer\gpr37l1b" - Cele\npr-4 "Xtro\ednra, Xtro\ednrb, Xtro\gpr37, Xtro\brs3, Xtro\ednrb2, Xtro\grpr" "Mmus\Mrgpre, Mmus\Mrgprh, Mmus\Mrgprg, Mmus\Mrgprb8, Mmus\Grpr, Mmus\Mrgprb2, Mmus\Ednra, Mmus\Mrgpra5, Mmus\Gpr151, Mmus\Mrgpra4, Mmus\Mrgpra9, Mmus\Mrgprx1, Mmus\Gpr37, Mmus\Ednrb, Mmus\Mrgpra2a, Mmus\Gpr37l1, Mmus\Mrgpra7, Mmus\Mrgprb5, Mmus\Brs3, Mmus\Mrgprx2, Mmus\Mrgprd, Mmus\Mrgprb3, Mmus\Mrgpra1, Mmus\Mrgpra3, Mmus\Mrgprb4, Mmus\Mrgpra8, Mmus\Nmbr, Mmus\Mrgprf, Mmus\Mrgpra6, Mmus\Mas1, Mmus\Mrgprb1" "Hsap\MRGPRG, Hsap\MRGPRE, Hsap\GRPR, Hsap\MRGPRX3, Hsap\GPR151, Hsap\MAS1L, Hsap\MRGPRX4, Hsap\BRS3, Hsap\NMBR, Hsap\MAS1, Hsap\MRGPRX1, Hsap\EDNRB, Hsap\GPR37, Hsap\MRGPRF, Hsap\EDNRA, Hsap\GPR37L1, Hsap\MRGPRD, Hsap\MRGPRX2" "viable,fertile" FBgn0046302 CG10650 - http://flybase.org/reports/FBgn0046302 protein_coding_gene - - - "BEST:GH09876, CG10650" IPR008472:Domain of unknown function DUF753 CG10650 27-Aug-18 DroID_v2018_08 - - Cele\M02G9.3 - - - "viable,fertile" FBgn0051295 CG31295 - http://flybase.org/reports/FBgn0051295 protein_coding_gene - - - "BcDNA:SD17750, CG31295" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065787 l(2)SH0433 lethal (2) SH0433 http://flybase.org/reports/FBgn0065787 gene - - - "l(2)SH0433, l(2)SH2 0433" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0042111 CG18766 - http://flybase.org/reports/FBgn0042111 protein_coding_gene - - - "CG5995, CG18766" IPR026095:Myb/SANT-like DNA-binding domain-containing protein CG18766 27-Aug-18 DroID_v2018_08 Drer\msantd1 - - - Mmus\Msantd1 Hsap\MSANTD1 viable FBgn0034142 CG8306 - http://flybase.org/reports/FBgn0034142 protein_coding_gene fatty-acyl-CoA reductase (alcohol-forming) activity ; GO:0080019 | inferred from sequence or structural similarity with HGNC:26222 long-chain-fatty-acyl-CoA reductase activity ; GO:0050062 | inferred from sequence or structural similarity with UniProtKB:Q922J9 wax biosynthetic process ; GO:0010025 | inferred from sequence or structural similarity with UniProtKB:Q922J9 endomembrane system ; GO:0012505 | inferred from direct assay peroxisome ; GO:0005777 | inferred from sequence or structural similarity with UniProtKB:Q922J9 CG8306 "IPR013120:Male sterility, NAD-binding, IPR016040:NAD(P)-binding domain, IPR026055:Fatty acyl-CoA reductase, IPR033640:Fatty acyl-CoA reductase, C-terminal" CG8306 27-Aug-18 DroID_v2018_08 "Drer\far1, Drer\si:dkey-97m3.1" - "Cele\fard-1, Cele\F13D11.4" Xtro\far1 "Mmus\Far2, Mmus\Far1, Mmus\Hsd3b1" "Hsap\FAR2, Hsap\FAR1" lethal FBgn0013474 l(1)12P3 lethal (1) 12P3 http://flybase.org/reports/FBgn0013474 - gene - - - l(1)12P3 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" "ovariole,germline clone,egg,dorsal appendage" FBgn0265342 CG44296 - http://flybase.org/reports/FBgn0265342 protein_coding_gene cytochrome-c oxidase activity ; GO:0004129 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000329966 "mitochondrial electron transport, cytochrome c to oxygen ; GO:0006123 | inferred from biological aspect of ancestor with PANTHER:PTN000329966" mitochondrial respiratory chain complex IV ; GO:0005751 | inferred from biological aspect of ancestor with PANTHER:PTN000329966 CG44296 IPR004202:Cytochrome c oxidase subunit VIIc CG44296 27-Aug-18 DroID_v2018_08 Drer\cox7c Scer\COX8 Cele\F26E4.6 Xtro\cox7c Mmus\Cox7c Hsap\COX7C FBgn0020263 oro oroshigane http://flybase.org/reports/FBgn0020263 FBgn0015693 gene - - - "E(B)2A, oro" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" "embryonic/first instar larval cuticle,egg" FBgn0014455 Ahcy Adenosylhomocysteinase http://flybase.org/reports/FBgn0014455 - protein_coding_gene NAD binding ; GO:0051287 | inferred from electronic annotation with InterPro:IPR000043 adenosylhomocysteinase activity ; GO:0004013 | inferred from biological aspect of ancestor with PANTHER:PTN000602759 adenosylhomocysteinase activity ; GO:0004013 | inferred from sequence or structural similarity with EMBL:U18796 inferred from sequence or structural similarity with protein_id:AAA51682 inferred from sequence or structural similarity with protein_id:AAB25906 "one-carbon metabolic process ; GO:0006730 | inferred from electronic annotation with InterPro:IPR000043, InterPro:IPR020082 S-adenosylhomocysteine catabolic process ; GO:0019510 | inferred from electronic annotation with InterPro:IPR000043 S-adenosylmethionine cycle ; GO:0033353 | inferred from biological aspect of ancestor with PANTHER:PTN000602759" cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000602759 "CG11654, ahcY, SAHH, Ahcy13, Ahcy" "IPR000043:Adenosylhomocysteinase-like, IPR015878:S-adenosyl-L-homocysteine hydrolase, NAD binding domain, IPR020082:S-adenosyl-L-homocysteine hydrolase, conserved site, IPR034373:Adenosylhomocysteinase, IPR016040:NAD(P)-binding domain" CG11654 27-Aug-18 DroID_v2018_08 "Drer\zgc:158222, Drer\ahcyl1, Drer\ahcy, Drer\ahcyl2" Scer\SAH1 Cele\ahcy-1 "Xtro\ahcyl2, Xtro\ahcyl1, Xtro\ahcy" "Mmus\Ahcyl2, Mmus\Ahcy, Mmus\Gm4737, Mmus\Ahcyl1" "Hsap\AHCYL1, Hsap\AHCY, Hsap\AHCYL2" embryonic stage -- adult stage viable FBgn0035008 CG3494 - http://flybase.org/reports/FBgn0035008 protein_coding_gene - phagocytosis ; GO:0006909 | inferred from mutant phenotype - "CT11751, CG3494" "IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like, IPR003591:Leucine-rich repeat, typical subtype" CG3494 27-Aug-18 DroID_v2018_08 "Drer\lrrc40, Drer\lrrc30a" - - "Xtro\LOC100487847, Xtro\lrrc40, Xtro\lrrc10b, Xtro\lrrc10" "Mmus\Lrrc40, Mmus\Lrrc30" "Hsap\LRRC40, Hsap\LRRC30" viable FBgn0264441 lncRNA:CR43859 - http://flybase.org/reports/FBgn0264441 non_protein_coding_gene - - - CR43859 - CR43859 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038654 CG14298 - http://flybase.org/reports/FBgn0038654 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 - - CG14298 "IPR002223:Pancreatic trypsin inhibitor Kunitz domain, IPR020901:Proteinase inhibitor I2, Kunitz, conserved site" CG14298 27-Aug-18 DroID_v2018_08 Drer\tfpia - "Cele\C54D10.10, Cele\apl-1, Cele\T21D12.12, Cele\K11D12.6, Cele\piit-1" - Mmus\App Hsap\APP viable FBgn0004577 Pxd Peroxidase http://flybase.org/reports/FBgn0004577 - protein_coding_gene heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR010255 peroxidase activity ; GO:0004601 | inferred from biological aspect of ancestor with PANTHER:PTN000158755 peroxidase activity ; GO:0004601 | inferred from sequence or structural similarity oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR010255 response to oxidative stress ; GO:0006979 | inferred from electronic annotation with InterPro:IPR010255 phagocytosis ; GO:0006909 | inferred from mutant phenotype eggshell chorion assembly ; GO:0007306 | non-traceable author statement neurogenesis ; GO:0022008 | inferred from mutant phenotype response to ethanol ; GO:0045471 | inferred from mutant phenotype chorion ; GO:0042600 | inferred from direct assay "CG3477, Dpxd, PO, DmPO, Pxd" "IPR010255:Haem peroxidase, IPR019791:Haem peroxidase, animal, IPR029585:Peroxidase, insect" CG3477 27-Aug-18 DroID_v2018_08 "Drer\ptgs2b, Drer\igsf9bb, Drer\tpo, Drer\ptgs1, Drer\ptgs2a" - "Cele\skpo-3, Cele\mlt-7, Cele\C46A5.4, Cele\pxn-1, Cele\K10B4.1, Cele\T06D8.10, Cele\F09F3.5, Cele\R08F11.7" "Xtro\epx, Xtro\pxdn, Xtro\tpo, Xtro\ptgs1, Xtro\ptgs2, Xtro\mpo" "Mmus\Epx, Mmus\Lpo, Mmus\Ptgs1, Mmus\Ptgs2, Mmus\Pxdn, Mmus\Tpo, Mmus\Mpo" "Hsap\PTGS2, Hsap\PXDN, Hsap\LPO, Hsap\PXDNL, Hsap\PTGS1, Hsap\TPO, Hsap\MPO, Hsap\EPX" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0002313 l(3)85Ad lethal (3) 85Ad http://flybase.org/reports/FBgn0002313 - gene - - - "L4, l(3)85Ad" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0037182 ArfGAP3 ADP-ribosylation factor GTPase activating protein 3 http://flybase.org/reports/FBgn0037182 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from electronic annotation with InterPro:IPR001164 GTPase activator activity ; GO:0005096 | inferred from sequence model compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype regulation of GTPase activity ; GO:0043087 | inferred from sequence model lateral inhibition ; GO:0046331 | inferred from mutant phenotype adherens junction ; GO:0005912 | colocalizes_with inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG6838, ArfGAP3, dArfGAP3, arfgap1, AG2" IPR001164:Arf GTPase activating protein CG6838 27-Aug-18 DroID_v2018_08 "Drer\arfgap2, Drer\arfgap3, Drer\terfa" "Scer\GLO3, Scer\SPS18" "Cele\F07F6.4, Cele\cnt-2" Xtro\arfgap2 "Mmus\Arfgap3, Mmus\Arfgap2" "Hsap\ARFGAP3, Hsap\ARFGAP2" "viable,visible" "chaeta,ommatidium,retina" FBgn0250754 CG42232 - http://flybase.org/reports/FBgn0250754 protein_coding_gene - - - "CG42232, clone 1.14, anon-EST:Liang-1.14, CG14896, CG14897" IPR008984:SMAD/FHA domain CG42232 27-Aug-18 DroID_v2018_08 Drer\mki67 - Cele\ret-1 - "Mmus\Cmya5, Mmus\Ank2, Mmus\Rtn4" "Hsap\RTN3, Hsap\RTN4, Hsap\MAP1A" FBgn0046654 anon-38D.10 anon-38D.10 http://flybase.org/reports/FBgn0046654 gene - - - "38D.10, anon-38D.10" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000031 AcpGI Accessory gland protein G-I http://flybase.org/reports/FBgn0000031 - gene - - - "AcpG, Acp-g1, AcpGI" - - 27-Aug-18 DroID_v2018_08 - - - - - - electrophoretic variant FBgn0005675 Dia2 Diaphorase 2 http://flybase.org/reports/FBgn0005675 - gene dihydrolipoyl dehydrogenase activity ; GO:0004148 | inferred from direct assay - - "DIA-2, Dia2" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0058409 CG40409 - http://flybase.org/reports/FBgn0058409 protein_coding_gene - - - CG40409 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0066071 Su(var)2-15 Su(var)2-15 http://flybase.org/reports/FBgn0066071 gene - - - Su(var)2-15 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001479 l(1)9Fg lethal (1) 9Fg http://flybase.org/reports/FBgn0001479 - gene - - - "l(1)BP3, l(1)v5, l(1)v40, l(1)v363, l(1)v207, l(1)v205, l(1)v172, l(1)v103, l(1)9Fg" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,partially lethal - majority die,lethal - all die before end of larval stage,some die during larval stage" FBgn0011811 l(3)s3246 lethal (3) s3246 http://flybase.org/reports/FBgn0011811 - gene - - - l(3)s3246 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0065045 spd slow-phase-defective http://flybase.org/reports/FBgn0065045 gene - - - spd - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004995 crisp crisp http://flybase.org/reports/FBgn0004995 - gene - - - "crisp, cr" - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive,viable" macrochaeta FBgn0022979 rrpB reduced receptor potential B http://flybase.org/reports/FBgn0022979 - gene - - - rrpB - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033134 Tsp42El Tetraspanin 42El http://flybase.org/reports/FBgn0033134 protein_coding_gene molecular_function ; GO:0003674 | no biological data available sleep ; GO:0030431 | inferred from expression pattern cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence model "CG12840, Dm.Tsp42El, anon-EST:Posey244, Tsp42El, Tsp42E1" "IPR018499:Tetraspanin/Peripherin, IPR008952:Tetraspanin, EC2 domain, IPR000301:Tetraspanin" CG12840 27-Aug-18 DroID_v2018_08 "Drer\cd63, Drer\tspan4a" - "Cele\tsp-3, Cele\tsp-2, Cele\tsp-7, Cele\tsp-1, Cele\tsp-14" Xtro\tspan3 Mmus\Cd63 Hsap\CD63 viable FBgn0001367 l(1)1Ff lethal (1) 1Ff http://flybase.org/reports/FBgn0001367 - gene - - - l(1)1Ff - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,germline clone,rescuable maternal effect" FBgn0033934 CG17385 - http://flybase.org/reports/FBgn0033934 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - "CG17385, CC7" IPR013087:Zinc finger C2H2-type CG17385 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-253d23.2, Drer\znf1157, Drer\zgc:113372, Drer\zgc:171422, Drer\zgc:173693, Drer\si:dkey-15h8.16, Drer\LOC100535506, Drer\zgc:100951, Drer\znf1184, Drer\zgc:110821, Drer\si:dkeyp-2e4.8, Drer\si:dkey-1b17.5, Drer\si:ch211-161m3.4, Drer\si:dkey-1b17.8, Drer\znf1154, Drer\si:ch211-241e1.5, Drer\znf990, Drer\znf1169, Drer\znf1002, Drer\zgc:113886, Drer\zgc:66483, Drer\znf1161, Drer\znf1003, Drer\zgc:174623, Drer\znf1173, Drer\zgc:113030, Drer\zgc:113452" "Scer\AZF1, Scer\ZAP1" "Cele\ZK686.5, Cele\che-1, Cele\ztf-23, Cele\fezf-1, Cele\let-391, Cele\Y55F3AM.14" - "Mmus\5730507C01Rik, Mmus\Zfp985, Mmus\Zfp936" "Hsap\ZNF383, Hsap\ZNF286B, Hsap\ZNF454, Hsap\ZNF502, Hsap\ZNF883" "viable,visible" trichogen cell DRSC06664 EK 1.278973039 0.940801573 3.593102745 0.056067651 -0.369641076 1.562939491 FBgn0036121 CG6310 - http://flybase.org/reports/FBgn0036121 protein_coding_gene - - - "BcDNA:AT03632, CG6310" IPR023393:START-like domain CG6310 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0028588 l(?)AP17 lethal (?) AP17 http://flybase.org/reports/FBgn0028588 gene - - - l(?)AP17 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0069936 CG41113 - http://flybase.org/reports/FBgn0069936 protein_coding_gene - - - CG41113 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0011613 l(1)I33e30 lethal (1) I33e30 http://flybase.org/reports/FBgn0011613 FBgn0010206 gene - - - "l(1)33e30, l(1)I33e30" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0262567 CG43107 - http://flybase.org/reports/FBgn0262567 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43107, MIP12466, lincRNA.331" - CG43107 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002309 l(3)84Fg lethal (3) 84Fg http://flybase.org/reports/FBgn0002309 - gene - - - "l(3)EfH2, l(3)84Fg" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0034361 mRpS28 mitochondrial ribosomal protein S28 http://flybase.org/reports/FBgn0034361 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:P82673 structural constituent of ribosome ; GO:0003735 | traceable author statement translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:P82673 mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial small ribosomal subunit ; GO:0005763 | traceable author statement mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:P82673 "MRP-S35, CG5497, BcDNA:RH13070, mRpS28, mrpS28" "IPR019375:Ribosomal protein S28, mitochondrial" CG5497 27-Aug-18 DroID_v2018_08 Drer\mrps28 - Cele\mrps-28 "Xtro\mrps28, Xtro\tpd52" Mmus\Mrps28 Hsap\MRPS28 "viable,visible" trichogen cell FBgn0261865 lgr lounger http://flybase.org/reports/FBgn0261865 gene - larval foraging behavior ; GO:0035177 | inferred from mutant phenotype - lgr - - 27-Aug-18 DroID_v2018_08 - - - - - - "behavior defective,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0002084 l(2)49Fm lethal (2) 49Fm http://flybase.org/reports/FBgn0002084 - gene - - - "vr-18, l(2)vr18, l(2)49Fm" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,non-suppressor of variegation,dominant" FBgn0002432 l(3)KE90 lethal (3) KE90 http://flybase.org/reports/FBgn0002432 - gene - - - l(3)KE90 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0034703 CG3045 - http://flybase.org/reports/FBgn0034703 protein_coding_gene "RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR001406, InterPro:IPR020094, InterPro:IPR020095, InterPro:IPR020097, InterPro:IPR020103 pseudouridine synthase activity ; GO:0009982 | inferred from biological aspect of ancestor with PANTHER:PTN000124732" mRNA pseudouridine synthesis ; GO:1990481 | inferred from biological aspect of ancestor with PANTHER:PTN000124846 tRNA pseudouridine synthesis ; GO:0031119 | inferred from biological aspect of ancestor with PANTHER:PTN000124732 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000124846 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000124846 CG3045 "IPR001406:Pseudouridine synthase I, TruA, IPR020095:Pseudouridine synthase I, TruA, C-terminal, IPR020097:Pseudouridine synthase I, TruA, alpha/beta domain, IPR020103:Pseudouridine synthase, catalytic domain" CG3045 27-Aug-18 DroID_v2018_08 "Drer\pus3, Drer\pusl1" "Scer\DEG1, Scer\PUS1" Cele\tag-124 Xtro\pus3 "Mmus\Pusl1, Mmus\Pus3" "Hsap\PUSL1, Hsap\PUS3" viable FBgn0052436 CG32436 - http://flybase.org/reports/FBgn0052436 protein_coding_gene - - - "CG6968, CG12973, CG32436, HD35012" - CG32436 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile,visible" "trichogen cell,supernumerary" FBgn0027164 l(2)KC-B l(2)Karp and Cherbas B http://flybase.org/reports/FBgn0027164 - gene - - - "B, l(2)KC-B" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0085778 CR40962 - http://flybase.org/reports/FBgn0085778 rRNA_gene - - - CR40962 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0003239 Rex Ribosomal exchange http://flybase.org/reports/FBgn0003239 - gene - - - "Su(Rex), Rex" - - 27-Aug-18 DroID_v2018_08 - - - - - - "mitotic cell cycle defective,maternal effect,semidominant" FBgn0262067 EG7 - http://flybase.org/reports/FBgn0262067 gene - - - EG7 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0014469 Cyp4e2 Cytochrome P450-4e2 http://flybase.org/reports/FBgn0014469 - protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" endomembrane system ; GO:0012505 | inferred from direct assay "4e2, CYP4E2, P450, P-450, Cyt-P450-4E2, CG2060, Cyp4e2, CyP4e2, Cyp4E2" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG2060 27-Aug-18 DroID_v2018_08 "Drer\cyp26c1, Drer\cyp19a1b, Drer\cyp46a1.1, Drer\cyp19a1a, Drer\cyp26b1, Drer\LOC100329425, Drer\cyp3c3, Drer\cyp3c2, Drer\cyp3c4, Drer\cyp46a1.2, Drer\cyp46a1.4, Drer\cyp20a1, Drer\cyp26a1, Drer\cyp4f3, Drer\cyp4v7, Drer\cyp3a65, Drer\cyp46a1.3, Drer\cyp3c1, Drer\cyp4v8, Drer\cyp4t8" "Scer\ERG5, Scer\DIT2" "Cele\cyp-31A3, Cele\cyp-13A3, Cele\cyp-13A8, Cele\cyp-37B1, Cele\cyp-13A11, Cele\cyp-13A7, Cele\cyp-13A12, Cele\cyp-32B1, Cele\cyp-42A1, Cele\cyp-25A2, Cele\cyp-32A1, Cele\cyp-29A4, Cele\cyp-29A3, Cele\cyp-13A10, Cele\cyp-37A1, Cele\cyp-25A4, Cele\cyp-25A1, Cele\cyp-25A3, Cele\cyp-13A5, Cele\cyp-29A2, Cele\cyp-13A1, Cele\cyp-31A5, Cele\cyp-31A2, Cele\cyp-13A4" "Xtro\cyp4v2, Xtro\cyp4f22, Xtro\mgc108213, Xtro\cyp26c1, Xtro\cyp4b1.2, Xtro\cyp26a1, Xtro\LOC100488227, Xtro\cyp4f2, Xtro\cyp19a1, Xtro\cyp4b1, Xtro\LOC100487918, Xtro\cyp20a1, Xtro\cyp26b1" "Mmus\Cyp26b1, Mmus\Cyp3a41b, Mmus\Cyp4f39, Mmus\Cyp19a1, Mmus\Cyp4f15, Mmus\Cyp4f18, Mmus\Cyp4a10, Mmus\Cyp26a1, Mmus\Cyp4f14, Mmus\Cyp4f37, Mmus\Cyp3a16, Mmus\Cyp20a1, Mmus\Cyp3a25, Mmus\Cyp3a41a, Mmus\Cyp26c1, Mmus\Cyp4f16, Mmus\Cyp4f40, Mmus\Cyp4a31, Mmus\Cyp4a32, Mmus\Cyp46a1, Mmus\Cyp4a29, Mmus\Cyp4f13, Mmus\Cyp4v3, Mmus\Cyp4x1, Mmus\Cyp3a59, Mmus\Cyp4a12a, Mmus\Cyp4f17, Mmus\Cyp4a14, Mmus\Cyp3a44, Mmus\Cyp4b1, Mmus\Cyp3a13, Mmus\Cyp4a12b, Mmus\Cyp4a30b, Mmus\Cyp3a57, Mmus\Cyp3a11" "Hsap\CYP4X1, Hsap\CYP4A22, Hsap\CYP4F8, Hsap\CYP4F11, Hsap\CYP4F22, Hsap\CYP19A1, Hsap\CYP26A1, Hsap\CYP26B1, Hsap\CYP3A43, Hsap\CYP4F12, Hsap\CYP4F3, Hsap\CYP20A1, Hsap\CYP4F2, Hsap\CYP26C1, Hsap\CYP3A7, Hsap\CYP3A4, Hsap\CYP4A11, Hsap\CYP4V2, Hsap\CYP4Z1, Hsap\CYP46A1, Hsap\CYP3A5, Hsap\CYP4B1" "viable,fertile,partially lethal - majority die,some die during pupal stage,lethal" FBgn0069211 hyp-Xh hyp-Xh http://flybase.org/reports/FBgn0069211 gene - - - "hyp[Xh], hyp-Xh" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039849 CG11334 - http://flybase.org/reports/FBgn0039849 protein_coding_gene S-methyl-5-thioribose-1-phosphate isomerase activity ; GO:0046523 | inferred from biological aspect of ancestor with PANTHER:PTN002460138 wing disc development ; GO:0035220 | inferred from genetic interaction with Bx L-methionine biosynthetic process from methylthioadenosine ; GO:0019509 | inferred from biological aspect of ancestor with PANTHER:PTN002460138 - CG11334 "IPR000649:Initiation factor 2B-related, IPR011559:Initiation factor 2B alpha/beta/delta, IPR005251:Methylthioribose-1-phosphate isomerase, IPR027363:Methylthioribose-1-phosphate isomerase-like, N-terminal domain" CG11334 27-Aug-18 DroID_v2018_08 Drer\mri1 Scer\MRI1 Cele\C01G10.9 Xtro\mri1 Mmus\Mri1 Hsap\MRI1 viable FBgn0266879 lncRNA:CR45340 - http://flybase.org/reports/FBgn0266879 non_protein_coding_gene - - - CR45340 - CR45340 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039266 CG11791 - http://flybase.org/reports/FBgn0039266 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG11791 - CG11791 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0032034 Rcd4 Reduction in Cnn dots 4 http://flybase.org/reports/FBgn0032034 protein_coding_gene - centriole replication ; GO:0007099 | inferred from mutant phenotype centriole ; GO:0005814 | inferred from direct assay "BcDNA:SD16838, Rcd4, CG17295" "IPR029135:Protein phosphatase 1 regulatory subunit 35, C-terminal" CG17295 27-Aug-18 DroID_v2018_08 - - - - - - "visible,body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0065869 l(2)SH0260 lethal (2) SH0260 http://flybase.org/reports/FBgn0065869 gene - - - "l(2)SH0260, l(2)SH2 0260" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0267327 Acp33A Accessory gland-specific peptide 33A http://flybase.org/reports/FBgn0267327 protein_coding_gene hormone activity ; GO:0005179 | non-traceable author statement "multicellular organism reproduction ; GO:0032504 | inferred from expression pattern negative regulation of female receptivity, post-mating ; GO:0045434 | non-traceable author statement" extracellular space ; GO:0005615 | inferred from direct assay extracellular region ; GO:0005576 | traceable author statement extracellular space ; GO:0005615 | inferred from sequence model "CG15841, CG6555, Acp33A, Acp33a, CG32952-A, CG32952" - CG6555 27-Aug-18 DroID_v2018_08 - - - - - - adult stage | male " male accessory gland main cell

, male accessory gland

" FBgn0259285 EP-800 - http://flybase.org/reports/FBgn0259285 gene - - - EP-800 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing,wing margin,chaeta" FBgn0050428 CG30428 - http://flybase.org/reports/FBgn0050428 protein_coding_gene - apoptotic process ; GO:0006915 | inferred from electronic annotation with InterPro:IPR026753 nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR026753 "BcDNA:SD21514, CG30428" "IPR026753:Nuclear apoptosis-inducing factor 1, IPR028002:Myb/SANT-like DNA-binding domain" CG30428 27-Aug-18 DroID_v2018_08 "Drer\zgc:153990, Drer\naif1, Drer\zgc:113149, Drer\si:ch211-261d7.3" - - - Mmus\Naif1 Hsap\NAIF1 viable FBgn0266474 pistachio-26F pistachio at 26F http://flybase.org/reports/FBgn0266474 gene - - - "pistachio-26F, pistachio" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal "egg chamber,cell non-autonomous,somatic clone,oocyte,germline clone" FBgn0044074 E(rst)I2 E(rst)I2 http://flybase.org/reports/FBgn0044074 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "I2, E(rst)I2" - - 27-Aug-18 DroID_v2018_08 - - - - - - viable eye FBgn0285950 RpL19 Ribosomal protein L19 http://flybase.org/reports/FBgn0002607 "FBgn0010030, FBgn0022215, FBgn0025292" protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from direct assay "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR000196, InterPro:IPR015972, InterPro:IPR015974 cytoplasmic translation ; GO:0002181 | traceable author statement centrosome duplication ; GO:0051298 | inferred from mutant phenotype cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626" cytosolic large ribosomal subunit ; GO:0022625 | inferred from electronic annotation with InterPro:IPR033935 cytosolic ribosome ; GO:0022626 | inferred from direct assay cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement ribosome ; GO:0005840 | inferred from direct assay "rpl19, l(2)k03704, rpL19, M(2)60E, E(Dl)KP135, L19, M(2)c, anon-EST:Posey33, M(2)a, CG2746, RpL19, M60E, Rp L19, Rpl19, RPL19" "IPR015972:Ribosomal protein L19/L19e, domain 1, IPR015974:Ribosomal protein L19/L19e, domain 3, IPR000196:Ribosomal protein L19/L19e, IPR033935:Ribosomal protein L19, eukaryotic, IPR015973:Ribosomal protein L19/L19e, domain 2, IPR023638:Ribosomal protein L19/L19e conserved site" CG2746 27-Aug-18 DroID_v2018_08 Drer\rpl19 "Scer\RPL19A, Scer\RPL19B" Cele\rpl-19 Xtro\rpl19 Mmus\Rpl19 Hsap\RPL19 "lethal,recessive,visible,dominant,developmental rate defective,viable" macrochaeta DRSC04649 IEK -2.445740034 -1.638076225 0.659973874 -2.036295371 2.776347035 3.735108756 1 FBgn0034674 CG9304 - http://flybase.org/reports/FBgn0034674 protein_coding_gene - G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR019336 response to pheromone ; GO:0019236 | inferred from electronic annotation with InterPro:IPR019336 - CG9304 "IPR019336:Intimal thickness related receptor, IRP" CG9304 27-Aug-18 DroID_v2018_08 "Drer\tmem145, Drer\gpr180" - "Cele\T04F8.2, Cele\C15A7.2" "Xtro\gpr180, Xtro\tmem145" "Mmus\Gpr180, Mmus\Tmem145" "Hsap\GPR180, Hsap\TMEM145" viable FBgn0011905 tRNA:Lys-TTT-2-5 transfer RNA:Lysine-TTT 2-5 http://flybase.org/reports/FBgn0011905 "FBgn0003793, FBgn0011901, FBgn0051197, FBgn0060171" tRNA_gene AAA codon-amino acid adaptor activity ; GO:0033443 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033443 cytosol ; GO:0005829 | inferred by curator from GO:0033443 "AE002708.trna3-LysTTT, tRNA:K5, tRNA:K:TTT:AE002708, CR31197, tRNA:lys5:87BC, chr3R.trna9-LysTTT, tRNA-Lys-TTT-2-5, tRNA:Lys-TTT-2-5, tRNA:K5:87BC, AAA" - CR31197 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0016849 l(1)N30 lethal (1) N30 http://flybase.org/reports/FBgn0016849 - gene - - - "l(1)N30, N30" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0001630 l(1)dn7 lethal (1) discs normal 7 http://flybase.org/reports/FBgn0001630 - gene - - - "l(1)d.norm.-7, l(1)dn7" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0030207 CG2887 - http://flybase.org/reports/FBgn0030207 protein_coding_gene unfolded protein binding ; GO:0051082 | inferred from electronic annotation with InterPro:IPR008971 protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR008971 - CG2887 "IPR001623:DnaJ domain, IPR002939:Chaperone DnaJ, C-terminal, IPR008971:HSP40/DnaJ peptide-binding, IPR018253:DnaJ domain, conserved site" CG2887 27-Aug-18 DroID_v2018_08 "Drer\dnajb5, Drer\dnajb1b, Drer\dnajb4, Drer\dnajb2, Drer\zgc:122979, Drer\dnajc22, Drer\dnajb1a" "Scer\SIS1, Scer\JJJ1, Scer\APJ1, Scer\JJJ3, Scer\JJJ2, Scer\ERJ5, Scer\SCJ1" "Cele\F54F2.9, Cele\dnj-19, Cele\dnj-22, Cele\dnj-12, Cele\dnj-13, Cele\dnj-1" "Xtro\dnajb4, Xtro\dnajb1, Xtro\dnajb5" "Mmus\4930503B20Rik, Mmus\Dnajb5, Mmus\Dnajc22, Mmus\Dnajb4, Mmus\Dnajb1" "Hsap\DNAJB5, Hsap\DNAJB1, Hsap\DNAJB4, Hsap\DNAJC22" viable FBgn0014981 l(2)46Cb lethal (2) 46Cb http://flybase.org/reports/FBgn0014981 - gene - - - "II, l(2)46Cb" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0001220 Hsc70-5 Heat shock protein cognate 5 http://flybase.org/reports/FBgn0001220 FBgn0022196 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR012725 unfolded protein binding ; GO:0051082 | inferred from sequence or structural similarity with UniProtKB:P38646 positive regulation of mitochondrial membrane potential ; GO:0010918 | inferred from mutant phenotype mitochondrion morphogenesis ; GO:0070584 | inferred from mutant phenotype mitophagy ; GO:0000422 | inferred from mutant phenotype protein folding ; GO:0006457 | inferred from sequence or structural similarity with UniProtKB:P38646 microtubule associated complex ; GO:0005875 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:P38646 "Hsc70-5, Hsc70, HSC-70, HSC70, Hsc5, l(2)k04907, hsc70, dhsc70, HSC5, CG8542, hsc-70-5, Hsc-5, HSC70-5, hsc70-5, Hsp-c5, hsc5" "IPR018181:Heat shock protein 70, conserved site, IPR012725:Chaperone DnaK, IPR013126:Heat shock protein 70 family, IPR029048:Heat shock protein 70kD, C-terminal domain, IPR029047:Heat shock protein 70kD, peptide-binding domain" CG8542 27-Aug-18 DroID_v2018_08 Drer\hspa9 "Scer\ECM10, Scer\SSQ1, Scer\SSC1" Cele\hsp-6 Xtro\hspa9 Mmus\Hspa9 Hsap\HSPA9 "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,female sterile,majority die during pupal stage,short lived,temperature conditional,locomotor rhythm defective,progressive,majority die during second instar larval stage,viable,majority die during third instar larval stage" mitochondrion DRSC07442 I -2.417277797 0.141278778 -0.61489733 -0.064526791 0.290182729 -0.38384767 FBgn0037301 Mms19 Mms19 http://flybase.org/reports/FBgn0037301 protein_coding_gene - - - "dMMS19, NEST:bs07f08, CG12005, Mms19, MMS19, mms19" "IPR016024:Armadillo-type fold, IPR024687:MMS19, C-terminal, IPR011989:Armadillo-like helical" CG12005 27-Aug-18 DroID_v2018_08 Drer\mms19 Scer\MET18 Cele\mms-19 Xtro\mms19 Mmus\Mms19 Hsap\MMS19 "lethal,recessive,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0031773 Fbw5 F-box and WD repeat domain containing 5 http://flybase.org/reports/FBgn0031773 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9XYZ5 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from sequence or structural similarity with UniProtKB:Q969U6 protein ubiquitination ; GO:0016567 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN000470116 positive regulation of protein catabolic process ; GO:0045732 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | traceable author statement SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model ubiquitin ligase complex ; GO:0000151 | inferred from biological aspect of ancestor with PANTHER:PTN000470116 SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model Cul4-RING E3 ubiquitin ligase complex ; GO:0080008 | inferred from sequence or structural similarity with HGNC:13613 "dFbw5, Fbw5, CG9144, FBgn 31773, FBXW2" "IPR001680:WD40 repeat, IPR001810:F-box domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain" CG9144 27-Aug-18 DroID_v2018_08 Drer\fbxw5 Scer\UFO1 - Xtro\fbxw5 Mmus\Fbxw5 Hsap\FBXW5 "viable,visible" "chaeta,supernumerary" DRSC29431 K 0.708787475 0.142056538 0.929483605 -0.69605949 1.52389324 -0.083941674 FBgn0029860 CG15891 - http://flybase.org/reports/FBgn0029860 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG32918, CG15891, CG15892" IPR023340:UMA domain CG15891 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" FBgn0259329 C573 - http://flybase.org/reports/FBgn0259329 gene - - - C573 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing,wing margin,chaeta" FBgn0040687 CG14645 - http://flybase.org/reports/FBgn0040687 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG14645 IPR002557:Chitin binding domain CG14645 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0038292 CG3987 - http://flybase.org/reports/FBgn0038292 protein_coding_gene - mesoderm development ; GO:0007498 | inferred from expression pattern - "CG3987, anon-WO0140519.215" - CG3987 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" FBgn0266802 asRNA:CR45264 - http://flybase.org/reports/FBgn0266802 non_protein_coding_gene - - - CR45264 - CR45264 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0013612 l(3)L0021 lethal (3) L0021 http://flybase.org/reports/FBgn0013612 - gene - - - l(3)L0021 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0045770 S-Lap3 Sperm-Leucylaminopeptidase 3 http://flybase.org/reports/FBgn0045770 protein_coding_gene "aminopeptidase activity ; GO:0004177 | inferred from electronic annotation with InterPro:IPR000819, InterPro:IPR008283, InterPro:IPR011356 metalloexopeptidase activity ; GO:0008235 | inferred from electronic annotation with InterPro:IPR011356 manganese ion binding ; GO:0030145 | inferred from electronic annotation with InterPro:IPR011356" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000819, InterPro:IPR008283" cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR011356 "CG8040, BEST:LP10167, anon-WO0140519.83, S-Lap3, CG32063, S-LAP 3, lincRNA.S4635" "IPR000819:Peptidase M17, leucyl aminopeptidase, C-terminal, IPR008283:Peptidase M17, leucyl aminopeptidase, N-terminal, IPR011356:Peptidase M17, leucine aminopeptidase/peptidase B" CG32063 27-Aug-18 DroID_v2018_08 "Drer\zgc:152830, Drer\rfwd2, Drer\lap3, Drer\npepl1" - "Cele\lap-2, Cele\lap-1" "Xtro\rfwd2, Xtro\lap3" "Mmus\Rfwd2, Mmus\Npepl1, Mmus\Lap3" "Hsap\NPEPL1, Hsap\LAP3" viable FBgn0027507 CG1344 - http://flybase.org/reports/FBgn0027507 - protein_coding_gene kinase activity ; GO:0016301 | NOT inferred from sequence or structural similarity with HGNC:19285 biological_process ; GO:0008150 | no biological data available cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:19285 "BcDNA:LD22679, CG1344" "IPR016024:Armadillo-type fold, IPR021133:HEAT, type 2, IPR011009:Protein kinase-like domain, IPR011989:Armadillo-like helical" CG1344 27-Aug-18 DroID_v2018_08 "Drer\scyl1, Drer\scyl3" Scer\CEX1 - "Xtro\scyl1, Xtro\scyl3" "Mmus\Scyl1, Mmus\Scyl3" "Hsap\SCYL3, Hsap\CDK3, Hsap\SCYL1, Hsap\CDK2" FBgn0000873 fs(1)M70 female sterile (1) M70 http://flybase.org/reports/FBgn0000873 - gene - - - fs(1)M70 - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive,lethal,maternal effect" FBgn0051830 CG31830 - http://flybase.org/reports/FBgn0051830 protein_coding_gene - - - CG31830 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0011721 TB9-3 TB9-3 http://flybase.org/reports/FBgn0011721 - gene - - - TB9-3 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266875 lncRNA:CR45336 - http://flybase.org/reports/FBgn0266875 non_protein_coding_gene - - - CR45336 - CR45336 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051810 CG31810 - http://flybase.org/reports/FBgn0051810 protein_coding_gene - - - "BcDNA:RE06583, CG31810" "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain" CG31810 27-Aug-18 DroID_v2018_08 "Drer\hsd20b2, Drer\hsd17b3, Drer\hsd17b12b, Drer\hsd17b12a, Drer\hsdl1" Scer\IFA38 "Cele\stdh-2, Cele\stdh-3, Cele\stdh-1, Cele\let-767, Cele\stdh-4, Cele\dhs-27, Cele\dhs-5" "Xtro\hsdl1, Xtro\LOC100497556, Xtro\hsd17b12" "Mmus\Hsd17b3, Mmus\Hsd17b12, Mmus\Hsdl1" "Hsap\HSD17B3, Hsap\HSD17B12, Hsap\HSDL1" FBgn0035164 CG13901 - http://flybase.org/reports/FBgn0035164 protein_coding_gene - - - CG13901 IPR026224:Protein DPCD CG13901 27-Aug-18 DroID_v2018_08 Drer\dpcd - - Xtro\dpcd Mmus\Dpcd Hsap\DPCD viable FBgn0062570 Mod(var)E1451 Mod(var)E1451 http://flybase.org/reports/FBgn0062570 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "E1451, Mod(var)E1451" - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,enhancer of variegation,non-enhancer of variegation,non-suppressor of variegation" FBgn0259379 C767 - http://flybase.org/reports/FBgn0259379 gene - - - C767 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing vein,wing margin" FBgn0262476 CG43066 - http://flybase.org/reports/FBgn0262476 protein_coding_gene neurotransmitter:sodium symporter activity ; GO:0005328 | inferred from electronic annotation with InterPro:IPR000175 transporter activity ; GO:0005215 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 neurotransmitter:sodium symporter activity ; GO:0005328 | inferred from sequence model neurotransmitter transporter activity ; GO:0005326 | inferred from sequence or structural similarity with DAT transport ; GO:0006810 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 neurotransmitter transport ; GO:0006836 | inferred from sequence or structural similarity with DAT neurotransmitter transport ; GO:0006836 | inferred from sequence model integral component of membrane ; GO:0016021 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 plasma membrane ; GO:0005886 | inferred from direct assay "CG43066, anon-WO0149848.1, CG5226, CG42510" IPR000175:Sodium:neurotransmitter symporter CG43066 27-Aug-18 DroID_v2018_08 "Drer\slc6a19a.1, Drer\slc6a1l, Drer\slc6a1b, Drer\slc6a5, Drer\slc6a13l, Drer\slc6a2, Drer\si:ch211-132b12.1, Drer\slc6a6a, Drer\si:ch211-132b12.6, Drer\slc6a4b, Drer\slc6a14, Drer\slc6a13, Drer\slc6a1a, Drer\slc6a6b, Drer\slc6a19b, Drer\slc6a4a, Drer\slc6a18, Drer\slc6a16a, Drer\zgc:158225, Drer\si:ch211-117c9.5, Drer\slc6a19a.2, Drer\slc6a11a, Drer\slc6a16b, Drer\slc6a17, Drer\si:ch211-132b12.2, Drer\slc6a15, Drer\slc6a13, Drer\slc6a9, Drer\slc6a8" - "Cele\mod-5, Cele\dat-1, Cele\snf-11, Cele\snf-6, Cele\snf-3" "Xtro\slc6a3, Xtro\slc6a12, Xtro\slc6a7, Xtro\slc6a13, Xtro\LOC100127682, Xtro\slc6a19, Xtro\slc6a15, Xtro\slc6a9, Xtro\slc6a14.2, Xtro\slc6a5, Xtro\slc6a17, Xtro\slc6a4, Xtro\slc6a16, Xtro\slc6a6, Xtro\slc6a8, Xtro\slc6a1, Xtro\slc6a2" "Mmus\Slc6a16, Mmus\Slc6a15, Mmus\Slc6a5, Mmus\Slc6a18, Mmus\Slc6a20b, Mmus\Slc6a21, Mmus\Slc6a4, Mmus\Slc6a8, Mmus\Slc6a2, Mmus\Slc6a14, Mmus\Slc6a9, Mmus\Slc6a7, Mmus\Slc6a1, Mmus\Slc6a6, Mmus\Slc6a3, Mmus\Slc6a12, Mmus\Slc6a19, Mmus\Slc6a13, Mmus\Slc6a11, Mmus\Slc6a17, Mmus\Slc6a20a" "Hsap\SLC6A19, Hsap\SLC6A4, Hsap\SLC6A5, Hsap\SLC6A14, Hsap\SLC6A12, Hsap\SLC6A1, Hsap\SLC6A20, Hsap\SLC6A11, Hsap\SLC6A6, Hsap\SLC6A13, Hsap\SLC6A8, Hsap\SLC6A9, Hsap\SLC6A18, Hsap\SLC6A16, Hsap\SLC6A15, Hsap\SLC6A2, Hsap\SLC6A17, Hsap\SLC6A7, Hsap\SLC6A3" FBgn0023040 l(2)46Ec lethal (2) 46Ec http://flybase.org/reports/FBgn0023040 FBgn0019725 gene - - - "G, 5.2, l(2)46CFc, l(2)46Ec" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0021991 l(2)k09613 lethal (2) k09613 http://flybase.org/reports/FBgn0021991 - gene - - - l(2)k09613 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0026348 Su(da[lyh])26E2 Su(da[lyh])26E2 http://flybase.org/reports/FBgn0026348 - gene - - - "Su(da[lyh]), Su(da[lyh])26E2" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267418 CR45771 - http://flybase.org/reports/FBgn0267418 pseudogene_attribute - - - "CR45771, Mst77Y" - CR45771 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037535 PIG-H Phosphatidylinositol glycan anchor biosynthesis class H http://flybase.org/reports/FBgn0037535 protein_coding_gene - GPI anchor biosynthetic process ; GO:0006506 | inferred from biological aspect of ancestor with PANTHER:PTN000391179 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex ; GO:0000506 | inferred from biological aspect of ancestor with PANTHER:PTN000391179 "PIG-H, CG14463" - CG14463 27-Aug-18 DroID_v2018_08 Drer\pigh Scer\GPI15 - - Mmus\Pigh Hsap\PIGH "viable,fertile" FBgn0053417 5SrRNA:CR33417 5SrRNA:CR33417 http://flybase.org/reports/FBgn0053417 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33417, 5SrRNA:CR33417" - CR33417 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0013667 ms(3)neo117 ms(3)neo117 http://flybase.org/reports/FBgn0013667 - gene - - - ms(3)neo117 - - 27-Aug-18 DroID_v2018_08 - - - - - - male sterile FBgn0025153 ms(2)A3 ms(2)A3 http://flybase.org/reports/FBgn0025153 - gene - - - ms(2)A3 - - 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,recessive" FBgn0016879 l(2)39DEd lethal (2) 39DEd http://flybase.org/reports/FBgn0016879 - gene - - - "H173, l(2)39DEd" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0083303 E(smoDN)1644 Enhancer of smoDN 1644 http://flybase.org/reports/FBgn0083303 gene - - - E(smoDN)1644 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002709 mei-218 meiotic 218 http://flybase.org/reports/FBgn0002709 "FBgn0053067, FBtr0089819, FBpp0088760, FBtr0089820, FBpp0088761, FBtr0089821, FBpp0088762" protein_coding_gene - reciprocal meiotic recombination ; GO:0007131 | traceable author statement reciprocal meiotic recombination ; GO:0007131 | inferred from mutant phenotype female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype female meiotic division ; GO:0007143 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay "CG8923, CG33067, mei-218" - CG8923 27-Aug-18 DroID_v2018_08 "Drer\mcmdc2, Drer\mcm4" Scer\MCM4 Cele\mcm-4 - "Mmus\Mcm4, Mmus\Mcmdc2" "Hsap\MCMDC2, Hsap\MCM4" "viable,meiotic cell cycle defective,female,fertile,female fertile,male fertile,wild-type,female semi-sterile,DNA repair defective" "cell cycle,oocyte,meiosis & nuclear chromosome | female" FBgn0036512 CG16979 - http://flybase.org/reports/FBgn0036512 protein_coding_gene thiolester hydrolase activity ; GO:0016790 | inferred from sequence or structural similarity with UniProtKB:Q9NUQ7 UFM1 hydrolase activity ; GO:0071567 | inferred from sequence or structural similarity with UniProtKB:Q9NUQ7 UFM1 hydrolase activity ; GO:0071567 | inferred from biological aspect of ancestor with PANTHER:PTN000325444 sleep ; GO:0030431 | inferred from expression pattern proteolysis ; GO:0006508 | inferred from sequence or structural similarity with UniProtKB:Q9NUQ7 endomembrane system ; GO:0012505 | inferred from direct assay CG16979 "IPR012462:Peptidase C78, ubiquitin fold modifier-specific peptidase 1/ 2" CG16979 27-Aug-18 DroID_v2018_08 "Drer\ufsp1, Drer\ufsp2" - Cele\odr-8 Xtro\ufsp2 "Mmus\Ufsp1, Mmus\Ufsp2" "Hsap\UFSP2, Hsap\UFSP1" FBgn0002246 l(3)68Ch lethal (3) 68Ch http://flybase.org/reports/FBgn0002246 - gene - - - "rsg7, l(3)rsg7, l(3)68Ch" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0011192 l(1)296-22 lethal (1) 296-22 http://flybase.org/reports/FBgn0011192 FBgn0010201 gene - - - "296-22, l(1)296-22" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0034463 CG15125 - http://flybase.org/reports/FBgn0034463 protein_coding_gene - - - CG15125 - CG15125 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0266441 CG45071 - http://flybase.org/reports/FBgn0266441 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR004210 "negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay" nucleus ; GO:0005634 | inferred from direct assay "CG45071, CG6854, Polypeptide A" "IPR004210:BESS motif, IPR006578:MADF domain" CG45071 27-Aug-18 DroID_v2018_08 - "Scer\URA8, Scer\URA7" - - Mmus\Ctps Hsap\CTPS1 FBgn0043806 CG32032 - http://flybase.org/reports/FBgn0043806 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BEST:GH25183, BcDNA:RH42907, CG32032" IPR012674:Calycin CG32032 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0023078 h::sna h::sna http://flybase.org/reports/FBgn0023078 - engineered_fusion_gene - - - h::sna - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,female" FBgn0065563 l(2)SH0983 lethal (2) SH0983 http://flybase.org/reports/FBgn0065563 gene - - - "l(2)SH0983, l(2)SH2 0983, SH0983" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0005697 l(3)88Ac lethal (3) 88Ac http://flybase.org/reports/FBgn0005697 - gene - - - l(3)88Ac - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,heat sensitive,cold sensitive" FBgn0028306 l(1)G0375 lethal (1) G0375 http://flybase.org/reports/FBgn0028306 gene - - - l(1)G0375 - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,male,female,recessive" FBgn0027133 l(3)99Ba lethal (3) 99Ba http://flybase.org/reports/FBgn0027133 - gene - - - l(3)99Ba - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0020810 mei-1725 mei-1725 http://flybase.org/reports/FBgn0020810 - gene - - - mei-1725 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030261 CG15203 - http://flybase.org/reports/FBgn0030261 protein_coding_gene - defense response to virus ; GO:0051607 | inferred from biological aspect of ancestor with PANTHER:PTN002219240 extracellular space ; GO:0005615 | inferred from sequence model "144845_at, CG15203, DIGF-1" IPR029277:Single domain Von Willebrand factor type C domain CG15203 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0029104 anon-21Ab anon-21Ab http://flybase.org/reports/FBgn0029104 gene - - - "X, anon-21Ab" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0042221 CG12435 - http://flybase.org/reports/FBgn0042221 protein_coding_gene - - - "CG18588, CG12435" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051145 CG31145 - http://flybase.org/reports/FBgn0051145 protein_coding_gene protein kinase activity ; GO:0004672 | inferred from sequence or structural similarity with fj protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with fj inferred from direct assay imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype Golgi apparatus ; GO:0005794 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay "CG13820, CG13821, CG10187, CG31145" "IPR009581:FAM20, C-terminal, IPR024869:FAM20, IPR015943:WD40/YVTN repeat-like-containing domain" CG31145 27-Aug-18 DroID_v2018_08 "Drer\fam20cl, Drer\fam20cb, Drer\fam20a, Drer\fam20ca, Drer\samd7, Drer\fam20b" - Cele\H03A11.1 "Xtro\fam20c, Xtro\fam20a, Xtro\fam20b, Xtro\samd7" "Mmus\Fam20b, Mmus\Fam20a, Mmus\Samd7, Mmus\Fam20c" "Hsap\FAM20C, Hsap\FAM20A, Hsap\FAM20B, Hsap\SAMD7" viable FBgn0265882 lncRNA:CR44671 - http://flybase.org/reports/FBgn0265882 non_protein_coding_gene - - - "CR44671, lincRNA.607" - CR44671 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040475 SH3PX1 SH3 and PX domain containing 1 http://flybase.org/reports/FBgn0040475 protein_coding_gene "phosphatidylinositol-4,5-bisphosphate binding ; GO:0005546 | inferred from sequence or structural similarity with HGNC:19245" mitotic nuclear division ; GO:0007067 | inferred from electronic annotation with InterPro:IPR014536 protein transport ; GO:0015031 | inferred from electronic annotation with InterPro:IPR014536 presynaptic active zone organization ; GO:1990709 | inferred from mutant phenotype cellular response to hypoxia ; GO:0071456 | inferred from mutant phenotype positive regulation of neurotransmitter secretion ; GO:0001956 | inferred from mutant phenotype lamellipodium assembly ; GO:0030032 | inferred from mutant phenotype autophagosome assembly ; GO:0000045 | inferred from mutant phenotype cytoplasmic vesicle ; GO:0031410 | inferred from biological aspect of ancestor with PANTHER:PTN000831156 subsynaptic reticulum ; GO:0071212 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay presynaptic membrane ; GO:0042734 | inferred from direct assay perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay terminal bouton ; GO:0043195 | inferred from direct assay "DSH3PX1, p63, CG6757, SH3PX1, DSH3PX, dSH3PX1, DmSNX18, sh3px1" "IPR001452:SH3 domain, IPR001683:Phox homologous domain, IPR014536:Sorting nexin 9 subfamily, IPR019497:Sorting nexin protein, WASP-binding domain" CG6757 27-Aug-18 DroID_v2018_08 "Drer\snx18a, Drer\snx33, Drer\snx9b, Drer\snx9a, Drer\snx18b, Drer\snx1a" "Scer\SNX4, Scer\VPS5" "Cele\snx-1, Cele\lst-4, Cele\snx-6" "Xtro\snx30, Xtro\snx18, Xtro\snx1, Xtro\snx33, Xtro\snx9" "Mmus\Snx18, Mmus\Snx9, Mmus\Snx30, Mmus\Snx1, Mmus\Snx33, Mmus\Snx2" "Hsap\SNX30, Hsap\SNX9, Hsap\SNX2, Hsap\SNX1, Hsap\SNX33, Hsap\SNX18" "viable,fertile" FBgn0062664 EP3140 EP3140 http://flybase.org/reports/FBgn0062664 gene - - - "EP(3)3140, EP3140" - - 27-Aug-18 DroID_v2018_08 - - - - - - neuroanatomy defective "embryonic/larval central nervous system,neurite | pharate adult stage" FBgn0046681 anon-38B.23 anon-38B.23 http://flybase.org/reports/FBgn0046681 gene - - - "38B.23, anon-38B.23" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0016918 ninaE::Rh2 ninaE::Rh2 http://flybase.org/reports/FBgn0016918 - engineered_fusion_gene - - - ninaE::Rh2 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030623 PPYR1 Protein phosphatase Y regulator 1 http://flybase.org/reports/FBgn0030623 protein_coding_gene - multicellular organism reproduction ; GO:0032504 | inferred from expression pattern cytoplasm ; GO:0005737 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay "BcDNA:AT19571, PPYR1, CG15031" IPR006861:Hyaluronan/mRNA-binding protein CG15031 27-Aug-18 DroID_v2018_08 "Drer\zgc:103482, Drer\serbp1b, Drer\serbp1a" "Scer\TMA10, Scer\STF2" "Cele\K01D12.9, Cele\vig-1, Cele\ZK285.2, Cele\K01D12.10, Cele\K01D12.8, Cele\R74.2" "Xtro\serbp1, Xtro\habp4" "Mmus\Habp4, Mmus\Serbp1" "Hsap\HABP4, Hsap\SERBP1" viable FBgn0013494 l(1)9PP12 lethal (1) 9PP12 http://flybase.org/reports/FBgn0013494 - gene - - - l(1)9PP12 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,germline clone,maternal effect" "embryo,germline clone,embryonic head" FBgn0038598 CG7131 - http://flybase.org/reports/FBgn0038598 protein_coding_gene microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR033336 molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon-WO0140519.212, CG7131" IPR033336:Stabilizer of axonemal microtubules 1/2 CG7131 27-Aug-18 DroID_v2018_08 Drer\saxo2 - "Cele\H03A11.2, Cele\T08G11.3, Cele\H13N06.7" Xtro\saxo2 "Mmus\Saxo1, Mmus\Saxo2" "Hsap\SAXO2, Hsap\SAXO1" FBgn0001221 Hsc70-6 Heat shock protein cognate 6 http://flybase.org/reports/FBgn0001221 - gene - - - "Hsc70, HSC-70, HSC70, hsc6, hsc70, dhsc70, Hsc6, Hsc70-6" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0067872 Mod(Prat:bw)3-3 Mod(Prat:bw)3-3 http://flybase.org/reports/FBgn0067872 gene - - - "Mod-3-3, Mod(Prat:bw)3-3" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0001701 l(1)ESHS22 lethal (1) ESHS22 http://flybase.org/reports/FBgn0001701 - gene - - - l(1)ESHS22 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0266211 CR44906 - http://flybase.org/reports/FBgn0266211 pseudogene_attribute - - - CR44906 - CR44906 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051778 CG31778 - http://flybase.org/reports/FBgn0051778 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 - - "BcDNA:HL03084, CG31778" IPR002223:Pancreatic trypsin inhibitor Kunitz domain CG31778 27-Aug-18 DroID_v2018_08 Drer\chtf18 Scer\CTF18 - Xtro\chtf18 Mmus\Chtf18 Hsap\CHTF18 viable FBgn0260324 GSd327 - http://flybase.org/reports/FBgn0260324 gene - - - GSd327 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0263512 Vsx2 Visual system homeobox 2 http://flybase.org/reports/FBgn0263512 protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with HGNC:1975" negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from sequence or structural similarity with HGNC:1975 optic lobe placode development ; GO:0001748 | inferred from expression pattern - "CG33980, Vsx2, Chx2, CG15783, CG15782, CG15781, dVsx2, DChx2, dChx2" "IPR023339:CVC domain, IPR001356:Homeobox domain, IPR003654:OAR domain, IPR009057:Homeobox domain-like, IPR017970:Homeobox, conserved site" CG33980 27-Aug-18 DroID_v2018_08 "Drer\alx4a, Drer\arxa, Drer\alx3, Drer\rx2, Drer\rx1, Drer\alx1, Drer\vsx1, Drer\vsx2" - "Cele\dsc-1, Cele\ceh-10" "Xtro\alx4, Xtro\alx1, Xtro\arx, Xtro\vsx2, Xtro\vsx1" "Mmus\Alx3, Mmus\Alx4, Mmus\Vsx2, Mmus\Vsx1, Mmus\Arx" "Hsap\ARX, Hsap\VSX2, Hsap\VSX1, Hsap\ALX4, Hsap\ALX3, Hsap\ALX1" FBgn0010120 l(1)2Dc lethal (1) 2Dc http://flybase.org/reports/FBgn0010120 - gene - - - "l(1)405, l(1)2Dc" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0033573 Obp47a Odorant-binding protein 47a http://flybase.org/reports/FBgn0033573 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush sensory perception of smell ; GO:0007608 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with UniProtKB:P34174 extracellular region ; GO:0005576 | inferred from sequence model extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 "47a, CG12944, Obp47a, DmelObp47a" IPR006170:Pheromone/general odorant binding protein CG12944 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0000067 ale almond eye http://flybase.org/reports/FBgn0000067 - gene - - - ale - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive" eye FBgn0030958 CR6900 - http://flybase.org/reports/FBgn0030958 pseudogene_attribute - - - "CG6900, CR6900" - CR6900 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0033052 SCAP SREBP cleavage activating protein http://flybase.org/reports/FBgn0033052 protein_coding_gene cholesterol binding ; GO:0015485 | inferred from electronic annotation with InterPro:IPR030225 SREBP signaling pathway ; GO:0032933 | inferred from electronic annotation with InterPro:IPR030225 cholesterol metabolic process ; GO:0008203 | inferred from electronic annotation with InterPro:IPR030225 sterol regulatory element binding protein cleavage ; GO:0035103 | non-traceable author statement protein processing ; GO:0016485 | non-traceable author statement endoplasmic reticulum membrane ; GO:0005789 | inferred from electronic annotation with InterPro:IPR030225 Golgi membrane ; GO:0000139 | inferred from electronic annotation with InterPro:IPR030225 "dSCAP, Scap_Dm, CG8356, CG14592, CG33131, SCAP, Scap, dScap, dscap" "IPR030225:Sterol regulatory element-binding protein cleavage-activating protein, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR000731:Sterol-sensing domain, IPR001680:WD40 repeat, IPR011047:Quinoprotein alcohol dehydrogenase-like superfamily, IPR011042:Six-bladed beta-propeller, TolB-like" CG33131 27-Aug-18 DroID_v2018_08 "Drer\npc1, Drer\scap, Drer\npc1l1" Scer\NCR1 Cele\scp-1 "Xtro\npc1l1, Xtro\npc1, Xtro\scap" "Mmus\Scap, Mmus\Npc1, Mmus\Npc1l1" "Hsap\NPC1L1, Hsap\NPC1, Hsap\SCAP" "viable,reduced,developmental rate defective" FBgn0035295 Cnb Centrobin http://flybase.org/reports/FBgn0035295 protein_coding_gene molecular_function ; GO:0003674 | no biological data available interphase microtubule organizing center assembly ; GO:0031024 | inferred from mutant phenotype protein localization to centrosome ; GO:0071539 | inferred from mutant phenotype centriole replication ; GO:0007099 | inferred from sequence or structural similarity with HGNC:29616 centriole ; GO:0005814 | inferred from direct assay "cDNA C, anon-62BCa, CG5690, Cnb, cnb" - CG5690 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-1o7.3, Drer\smc2" Scer\SMC2 "Cele\smc-4, Cele\M151.4, Cele\F14H3.4, Cele\F14H3.5" - "Mmus\Shtn1, Mmus\Golga2, Mmus\Swap70, Mmus\Smc2, Mmus\Hmmr, Mmus\Cntrob" "Hsap\CNTROB, Hsap\SHTN1, Hsap\SMC2" "mitotic cell cycle defective,viable" "centrioleED4284),embryonic/larval neuroblast,embryonic/larval neuroblast | larval stage,centrosomeunspecified,centriole" FBgn0265461 jurka - http://flybase.org/reports/FBgn0265461 gene - - - jurka - - 27-Aug-18 DroID_v2018_08 - - - - - - memory defective FBgn0265843 lncRNA:CR44632 - http://flybase.org/reports/FBgn0265843 non_protein_coding_gene - - - "lincRNA.355, CR44632" - CR44632 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085376 CG34347 - http://flybase.org/reports/FBgn0085376 protein_coding_gene structural constituent of cytoskeleton ; GO:0005200 | inferred from biological aspect of ancestor with PANTHER:PTN001150527 cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity actomyosin structure organization ; GO:0031032 | inferred from biological aspect of ancestor with PANTHER:PTN001150527 cytoskeleton ; GO:0005856 | inferred from biological aspect of ancestor with PANTHER:PTN001150527 "CG11339, CG34347, LP8211, CG15566, EST:LP08211" "IPR000299:FERM domain, IPR011993:PH domain-like, IPR014352:FERM/acyl-CoA-binding protein, 3-helical bundle, IPR019748:FERM central domain, IPR018980:FERM, C-terminal PH-like domain, IPR019749:Band 4.1 domain, IPR018979:FERM, N-terminal, IPR029071:Ubiquitin-related domain, IPR014847:FERM adjacent (FA)" CG34347 27-Aug-18 DroID_v2018_08 "Drer\frmd5, Drer\epb41l4a, Drer\epb41l4b, Drer\frmd3, Drer\LOC570903, Drer\frmd4ba" - Cele\frm-4 "Xtro\frmd5, Xtro\epb41l4a, Xtro\frmd3" "Mmus\Frmd3, Mmus\Frmd5, Mmus\Epb41l4a" "Hsap\FRMD5, Hsap\FRMD4A, Hsap\C1orf106, Hsap\EPB41L4A, Hsap\FRMD3, Hsap\FRMD4B" viable FBgn0265438 orb::orb2 - http://flybase.org/reports/FBgn0265438 engineered_fusion_gene - - - orb::orb2 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0010128 l(1)ts445b lethal (1) ts445b http://flybase.org/reports/FBgn0010128 - gene - - - l(1)ts445b - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,heat sensitive" FBgn0052312 tRNA:Cys-GCA-2-1 transfer RNA:Cysteine-GCA 2-1 http://flybase.org/reports/FBgn0052312 tRNA_gene UGC codon-amino acid adaptor activity ; GO:0033414 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033414 cytosol ; GO:0005829 | inferred by curator from GO:0033414 "AE002584.trna12-CysGCA, tRNA:C:GCA:AE002584-a, CR32312, chr3L.trna12-CysGCA, tRNA:Cys-GCA-2-1, tRNA:CR32312, tRNA-Cys-GCA-2-1, UGC" - CR32312 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0250742 l(3)S051513 lethal (3) S051513 http://flybase.org/reports/FBgn0250742 gene - - - "l(3)S051513, l(3)s051513" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0262115 CG17683 - http://flybase.org/reports/FBgn0262115 protein_coding_gene molecular_function ; GO:0003674 | no biological data available iron-sulfur cluster assembly ; GO:0016226 | inferred from sequence or structural similarity with UniProtKB:Q9H6Q4 neurogenesis ; GO:0022008 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG17683, NC38, l(2)NC38, NC70, l(2)NC70, NC37, l(2)NC37, NAR1p" "IPR003149:Iron hydrogenase, small subunit, IPR004108:Iron hydrogenase, large subunit, C-terminal, IPR009016:Iron hydrogenase" CG17683 27-Aug-18 DroID_v2018_08 "Drer\narf, Drer\narfl" Scer\NAR1 Cele\oxy-4 "Xtro\narf, Xtro\narfl" "Mmus\Narf, Mmus\Narfl" "Hsap\NARFL, Hsap\NARF" FBgn0005370 wh whiskers http://flybase.org/reports/FBgn0005370 - gene - - - wh - - 27-Aug-18 DroID_v2018_08 - - - - - - visible vibrissae FBgn0023467 anon-56Ca anon-56Ca http://flybase.org/reports/FBgn0023467 - gene - - - anon-56Ca - - 27-Aug-18 DroID_v2018_08 - - - - - - adult stage | male FBgn0051875 CG31875 - http://flybase.org/reports/FBgn0051875 protein_coding_gene "transcription factor binding ; GO:0008134 | inferred from biological aspect of ancestor with PANTHER:PTN001043031 transcription regulatory region DNA binding ; GO:0044212 | inferred from biological aspect of ancestor with PANTHER:PTN001043031 transcription corepressor activity ; GO:0003714 | inferred from biological aspect of ancestor with PANTHER:PTN000412750 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN001043031" negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from biological aspect of ancestor with PANTHER:PTN000412750 transcription factor complex ; GO:0005667 | inferred from biological aspect of ancestor with PANTHER:PTN001043031 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001043031 transcriptional repressor complex ; GO:0017053 | inferred from biological aspect of ancestor with PANTHER:PTN000412750 "CG5831, BcDNA:AT29184, CG31875, Desr" IPR000949:ELM2 domain CG31875 27-Aug-18 DroID_v2018_08 "Drer\ddx42, Drer\ddx46, Drer\rcor1, Drer\rcor2, Drer\rcor3" Scer\PRP5 "Cele\spr-1, Cele\rcor-1" "Xtro\ddx46, Xtro\rcor3, Xtro\rcor1, Xtro\rcor2, Xtro\ddx42" "Mmus\Rcor3, Mmus\Rcor1, Mmus\Ddx42, Mmus\Ddx46, Mmus\Rcor2" "Hsap\DDX46, Hsap\RCOR1, Hsap\DDX42, Hsap\RCOR3, Hsap\RCOR2" viable FBgn0265483 BG02419 - http://flybase.org/reports/FBgn0265483 gene - - - BG02419 - - 27-Aug-18 DroID_v2018_08 - - - - - - sleep defective FBgn0001555 l(1)19Ba lethal (1) 19Ba http://flybase.org/reports/FBgn0001555 - gene - - - l(1)19Ba - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0022098 l(2)k07204 lethal (2) k07204 http://flybase.org/reports/FBgn0022098 - gene - - - l(2)k07204 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0034566 CG9313 - http://flybase.org/reports/FBgn0034566 protein_coding_gene molecular_function ; GO:0003674 | no biological data available sensory perception of sound ; GO:0007605 | inferred from mutant phenotype cilium movement ; GO:0003341 | inferred from sequence or structural similarity with UniProtKB:Q9UI46 outer dynein arm ; GO:0036157 | inferred from sequence or structural similarity with UniProtKB:Q9UI46 CG9313 "IPR017986:WD40-repeat-containing domain, IPR001680:WD40 repeat, IPR015943:WD40/YVTN repeat-like-containing domain" CG9313 27-Aug-18 DroID_v2018_08 "Drer\dnai1.1, Drer\wdr34, Drer\dnai1.2" - Cele\prp-17 Xtro\wdr34 "Mmus\Wdr34, Mmus\Dnaic1" "Hsap\DNAI1, Hsap\WDR34" "auditory perception defective,neurophysiology defective,viable" FBgn0011410 l(3)j8B9 lethal (3) j8B9 http://flybase.org/reports/FBgn0011410 - gene - - - l(3)j8B9 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0025723 A122 A122 http://flybase.org/reports/FBgn0025723 - gene molecular_function ; GO:0003674 | no biological data available Notch signaling pathway ; GO:0007219 | inferred from genetic interaction with N sensory organ development ; GO:0007423 | inferred from genetic interaction with N cellular_component ; GO:0005575 | no biological data available A122 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0005437 l(1)v59 lethal (1) v59 http://flybase.org/reports/FBgn0005437 - gene - - - "l(1)59, l(1)v59" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266684 lncRNA:CR45174 - http://flybase.org/reports/FBgn0266684 non_protein_coding_gene - - - CR45174 - CR45174 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038397 CG10185 - http://flybase.org/reports/FBgn0038397 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG10185 "IPR001680:WD40 repeat, IPR011047:Quinoprotein alcohol dehydrogenase-like superfamily, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR019775:WD40 repeat, conserved site, IPR025139:Domain of unknown function DUF4062" CG10185 27-Aug-18 DroID_v2018_08 "Drer\nwd2, Drer\LOC101885341, Drer\nwd1, Drer\wdr18" Scer\IPI3 Cele\T05C3.2 Xtro\nwd2 "Mmus\Nwd1, Mmus\Wdr18, Mmus\Nwd2" "Hsap\WDR18, Hsap\NWD1, Hsap\NWD2" viable FBgn0023090 dtr defective transmitter release http://flybase.org/reports/FBgn0023090 FBgn0051623 protein_coding_gene dynein complex binding ; GO:0070840 | inferred from sequence or structural similarity with UniProtKB:Q7ZV84 motile cilium assembly ; GO:0044458 | inferred from electronic annotation with InterPro:IPR027734 chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype cilium assembly ; GO:0060271 | inferred from sequence or structural similarity with UniProtKB:Q7ZV84 axoneme ; GO:0005930 | inferred from sequence or structural similarity with UniProtKB:Q8NEP3 "CG31623, dtr, Dtr" "IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like, IPR027734:Dynein assembly factor 1, axonemal" CG31623 27-Aug-18 DroID_v2018_08 "Drer\tlr2, Drer\dnaaf1, Drer\tlr21, Drer\ppp1r42, Drer\tlr19" "Scer\SDS22, Scer\NUD1" Cele\gip-2 Xtro\ppp1r42 "Mmus\Ppp1r42, Mmus\Tlr2, Mmus\Dnaaf1" "Hsap\DNAAF1, Hsap\LRRCC1, Hsap\PPP1R42, Hsap\TLR2" "visual behavior defective,neurophysiology defective,viable" FBgn0004782 Ccp84Ab Ccp84Ab http://flybase.org/reports/FBgn0004782 - protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "cc7, CG1252, BG:DS00004.2, Ccp84Ab, Ccp, DmelCcp84Ab" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG1252 27-Aug-18 DroID_v2018_08 - - Cele\fbxb-38 - - - DRSC25096 K -0.100466093 -0.552837273 0.440149193 0.290791865 -1.529617353 -0.238832858 FBgn0261830 CG42762 - http://flybase.org/reports/FBgn0261830 protein_coding_gene - - - CG42762 - CG42762 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031969 pes peste http://flybase.org/reports/FBgn0031969 protein_coding_gene - - membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002159 "CG7228, Pes, pes" IPR002159:CD36 family CG7228 27-Aug-18 DroID_v2018_08 "Drer\cd36, Drer\LOC564077, Drer\scarb2, Drer\scarb1" - "Cele\scav-3, Cele\scav-6, Cele\scav-2, Cele\scav-1" "Xtro\cd36, Xtro\scarb2, Xtro\scarb1" "Mmus\Cd36, Mmus\Scarb1, Mmus\Scarb2" "Hsap\SCARB2, Hsap\CD36, Hsap\SCARB1" viable FBgn0043593 E(ro[DOM])2409 E(ro[DOM])2409 http://flybase.org/reports/FBgn0043593 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with ro cellular_component ; GO:0005575 | no biological data available E(ro[DOM])2409 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0062650 EP393 EP393 http://flybase.org/reports/FBgn0062650 gene - - - "EP(2)0393, EP393" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0017359 l(3)F51 lethal (3) F51 http://flybase.org/reports/FBgn0017359 - gene - - - "l(3)51, l(3)F51" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0038198 Npc2b Niemann-Pick type C-2b http://flybase.org/reports/FBgn0038198 protein_coding_gene sterol binding ; GO:0032934 | inferred from sequence or structural similarity with HGNC:14537 intracellular cholesterol transport ; GO:0032367 | inferred from electronic annotation with InterPro:IPR033916 ecdysteroid biosynthetic process ; GO:0045456 | inferred from genetic interaction with Npc2a sterol transport ; GO:0015918 | inferred from genetic interaction with Npc2a multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "CT10556, DmML2, Npc2b, CG3153, npc2b, NPC2" "IPR003172:MD-2-related lipid-recognition domain, IPR014756:Immunoglobulin E-set, IPR033916:ML domain, Npc2 like" CG3153 27-Aug-18 DroID_v2018_08 "Drer\zgc:193725, Drer\npc2" Scer\NPC2 Cele\heh-1 Xtro\npc2 Mmus\Npc2 Hsap\NPC2 "viable,fertile,visible,body color defective" mesothoracic tergum FBgn0065771 l(2)SH0462 lethal (2) SH0462 http://flybase.org/reports/FBgn0065771 gene - - - "l(2)SH0462, l(2)SH2 0462" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0040291 Roc1b Regulator of cullins 1b http://flybase.org/reports/FBgn0040291 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841, InterPro:IPR024766 ubiquitin protein ligase activity ; GO:0061630 | inferred from direct assay cullin family protein binding ; GO:0097602 | inferred from physical interaction with Cul3 zinc ion binding ; GO:0008270 | inferred from sequence model cullin family protein binding ; GO:0097602 | inferred from physical interaction with UniProtKB:Q8IP45" cell proliferation ; GO:0008283 | inferred from sequence or structural similarity with UniProtKB:Q9W5E1 protein ubiquitination ; GO:0016567 | inferred from direct assay flagellated sperm motility ; GO:0030317 | inferred from mutant phenotype lipid storage ; GO:0019915 | inferred from direct assay activation of cysteine-type endopeptidase activity involved in apoptotic process ; GO:0006919 | inferred from genetic interaction with Cul3 nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q9W5E1 SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence or structural similarity with UniProtKB:Q9W5E1 Cul3-RING ubiquitin ligase complex ; GO:0031463 | inferred from direct assay "ROC1b, CG16988, ROC2, ROC1B, dRoc1b, BcDNA:AT21612, Roc1b, Roc, roc1b" "IPR001841:Zinc finger, RING-type, IPR024766:Zinc finger, RING-H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG16988 27-Aug-18 DroID_v2018_08 "Drer\rbx1, Drer\rnf7" Scer\HRT1 "Cele\rbx-2, Cele\rbx-1" Xtro\rnf7 "Mmus\Rbx1, Mmus\Rnf7" "Hsap\RBX1, Hsap\RNF7" " embryonic stage -- adult stage , larval stage " " organism

, dorsal mesothoracic disc

ubiquitous " "viable,male sterile,male semi-sterile,increased cell death,somatic clone" "spermatozoon,spermatid" FBgn0010806 l(3)03644 lethal (3) 03644 http://flybase.org/reports/FBgn0010806 - gene - - - l(3)03644 - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0060564 l(3)S096516b lethal (3) S096516b http://flybase.org/reports/FBgn0060564 gene - - - "0965/16, l(3)S096516b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0039980 CG18160 - http://flybase.org/reports/FBgn0039980 protein_coding_gene - - - CG18160 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0024608 olfJ11 olfactory J11 http://flybase.org/reports/FBgn0024608 - gene - - - olfJ11 - - 27-Aug-18 DroID_v2018_08 - - - - - - smell perception defective FBgn0038600 CG12364 - http://flybase.org/reports/FBgn0038600 protein_coding_gene - - - CG12364 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040018 CG12631 - http://flybase.org/reports/FBgn0040018 protein_coding_gene - - - CG12631 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031479 Prx6005 Peroxiredoxin 6005 http://flybase.org/reports/FBgn0031479 protein_coding_gene peroxiredoxin activity ; GO:0051920 | inferred from electronic annotation with InterPro:IPR019479 peroxidase activity ; GO:0004601 | inferred from direct assay "cell redox homeostasis ; GO:0045454 | inferred from electronic annotation with InterPro:IPR013766 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000866, InterPro:IPR019479 hydrogen peroxide catabolic process ; GO:0042744 | inferred from direct assay" cytosol ; GO:0005829 | inferred from direct assay "153181_at, CG3083, DPx6005, Prx6005, GM04269p, DPx-6005" "IPR000866:Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant, IPR012336:Thioredoxin-like fold, IPR019479:Peroxiredoxin, C-terminal, IPR024706:Peroxiredoxin, AhpC-type, IPR013766:Thioredoxin domain" CG3083 27-Aug-18 DroID_v2018_08 "Drer\prdx3, Drer\prdx2, Drer\prdx6, Drer\prdx4, Drer\prdx1" "Scer\TSA2, Scer\PRX1, Scer\TSA1" "Cele\prdx-3, Cele\prdx-2, Cele\prdx-6" Xtro\prdx6 "Mmus\Prdx2, Mmus\Prdx6b, Mmus\Prdx4, Mmus\Prdx3, Mmus\Prdx1, Mmus\Prdx6" "Hsap\PRDX1, Hsap\PRDX6, Hsap\PRDX4, Hsap\PRDX2, Hsap\PRDX3" "viable,body color defective" mesothoracic tergum FBgn0040236 c11.1 c11.1 http://flybase.org/reports/FBgn0040236 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available Golgi apparatus ; GO:0005794 | inferred from direct assay late endosome ; GO:0005770 | inferred from direct assay "CG12132, c11.1, C11.1" "IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical" CG12132 27-Aug-18 DroID_v2018_08 Drer\mroh1 - Cele\hpo-27 Xtro\mroh1 "Mmus\Mro, Mmus\Mroh8, Mmus\Mroh7, Mmus\Mroh4, Mmus\Mroh2a, Mmus\Mroh1, Mmus\Mroh3, Mmus\Mroh6, Mmus\Mroh2b, Mmus\Mroh9" "Hsap\MROH5, Hsap\MROH9, Hsap\MRO, Hsap\MROH2B, Hsap\MROH1, Hsap\MROH2A, Hsap\MROH7, Hsap\MROH6, Hsap\MROH8" "viable,fertile" FBgn0028213 l(3)S010102a lethal (3) S010102a http://flybase.org/reports/FBgn0028213 gene - - - "0101/02, l(3)S010102, l(3)S010102a" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0029995 CG2256 - http://flybase.org/reports/FBgn0029995 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048, InterPro:IPR028846" - - CG2256 "IPR002048:EF-hand domain, IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site" CG2256 27-Aug-18 DroID_v2018_08 "Drer\efcab1, Drer\rcvrna, Drer\hpcal4, Drer\guca1a, Drer\vsnl1b, Drer\guca1e, Drer\ncs1b, Drer\ncalda, Drer\rcvrn2, Drer\ncs1a, Drer\kcnip2, Drer\si:ch211-145b13.5, Drer\guca1c, Drer\hpca, Drer\kcnip1b, Drer\guca1g, Drer\kcnip3b, Drer\kcnip1a, Drer\usp32, Drer\si:ch211-245j22.3, Drer\kcnip4, Drer\guca1d, Drer\si:ch211-103a14.5, Drer\vsnl1a, Drer\rcvrnb, Drer\rcvrn3, Drer\hpcal1, Drer\guca1b, Drer\ncaldb" Scer\FRQ1 - "Xtro\kcnip4, Xtro\ncald, Xtro\guca1a, Xtro\ncs1, Xtro\guca1b, Xtro\kcnip1, Xtro\kcnip2, Xtro\vsnl1, Xtro\rcvrn.2, Xtro\hpcal1, Xtro\hpca, Xtro\kcnip3, Xtro\efcab1, Xtro\guca1c" "Mmus\Kcnip1, Mmus\Kcnip3, Mmus\Rcvrn, Mmus\Efcab1, Mmus\Hpcal4, Mmus\Guca1a, Mmus\Guca1b, Mmus\Kcnip4, Mmus\Hpca, Mmus\Vsnl1, Mmus\1700109H08Rik, Mmus\Ncald, Mmus\Ncs1, Mmus\Hpcal1, Mmus\Kcnip2, Mmus\Usp32" "Hsap\VSNL1, Hsap\KCNIP4, Hsap\GUCA1A, Hsap\NCS1, Hsap\RCVRN, Hsap\HPCAL1, Hsap\KCNIP3, Hsap\USP32, Hsap\HPCA, Hsap\HPCAL4, Hsap\EFCAB1, Hsap\KCNIP2, Hsap\NCALD, Hsap\KCNIP1, Hsap\GUCA1C, Hsap\GUCA1B" viable FBgn0267733 lncRNA:CR46064 - http://flybase.org/reports/FBgn0267733 non_protein_coding_gene - - - CR46064 - CR46064 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0069098 mus327 mutagen-sensitive 327 http://flybase.org/reports/FBgn0069098 gene - - - mus327 - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,chemical sensitive" FBgn0004204 l(3)84Eb lethal (3) 84Eb http://flybase.org/reports/FBgn0004204 - gene - - - l(3)84Eb - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0015966 l(2)46DEd lethal (2) 46DEd http://flybase.org/reports/FBgn0015966 - gene - - - "group 8, l(2)46DEd" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0046253 CG3502 - http://flybase.org/reports/FBgn0046253 protein_coding_gene peptide binding ; GO:0042277 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 metalloaminopeptidase activity ; GO:0070006 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 peptide catabolic process ; GO:0043171 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 "BEST:LD34564, CG3502" "IPR024571:ERAP1-like C-terminal domain, IPR001930:Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR014782:Peptidase M1, membrane alanine aminopeptidase, N-terminal, IPR034016:Aminopeptidase N-type" CG3502 27-Aug-18 DroID_v2018_08 "Drer\npepps, Drer\erap2, Drer\si:ch211-106j24.1, Drer\si:ch211-276a23.5, Drer\si:ch211-149p5.1, Drer\erap1b, Drer\lnpep, Drer\anpepb, Drer\anpepa, Drer\si:ch211-198g19.1, Drer\erap1a, Drer\enpep" "Scer\AAP1, Scer\TMA108, Scer\APE2" "Cele\T12E12.6, Cele\R03G8.6, Cele\T07F10.1, Cele\Y67D8C.9, Cele\mnp-1, Cele\T16G12.1, Cele\F49B2.6, Cele\pam-1, Cele\VB0395L.1, Cele\R03G8.4, Cele\Y42A5A.1, Cele\AC3.5, Cele\Y53F4B.20" "Xtro\anpep, Xtro\lnpep, Xtro\lvrn, Xtro\npepps, Xtro\enpep, Xtro\erap1" "Mmus\Lnpep, Mmus\Enpep, Mmus\Lvrn, Mmus\Erap1, Mmus\Trhde, Mmus\Anpep, Mmus\Npepps" "Hsap\NPEPPS, Hsap\ANPEP, Hsap\ENPEP, Hsap\ERAP1, Hsap\TRHDE, Hsap\LVRN, Hsap\ERAP2, Hsap\LNPEP" viable FBgn0266365 lncRNA:CR45013 - http://flybase.org/reports/FBgn0266365 non_protein_coding_gene - - - CR45013 - CR45013 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266364 CG45012 - http://flybase.org/reports/FBgn0266364 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from biological aspect of ancestor with PANTHER:PTN001848130 negative regulation of serine-type endopeptidase activity ; GO:1900004 | inferred from biological aspect of ancestor with PANTHER:PTN001848130 cellular_component ; GO:0005575 | no biological data available CG45012 IPR002350:Kazal domain CG45012 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-203a12.2, Drer\si:dkey-77g12.4, Drer\si:dkey-77g12.1, Drer\si:dkey-203a12.4, Drer\si:dkey-203a12.6, Drer\si:dkey-203a12.8, Drer\si:dkey-203a12.3, Drer\zgc:158852" - - - "Mmus\Spink13, Mmus\Spink14, Mmus\Spink10, Mmus\Spink8, Mmus\Gm10267, Mmus\Spink2, Mmus\Spinkl, Mmus\Spink7, Mmus\Spink11, Mmus\Spink1" "Hsap\SPINK7, Hsap\SPINK8, Hsap\SPINK2, Hsap\SPINK13, Hsap\SPINK14, Hsap\SPINK1, Hsap\SPINK9" FBgn0031786 CG13989 - http://flybase.org/reports/FBgn0031786 protein_coding_gene - - - "BcDNA:AT09383, CG13989" - CG13989 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0052118 CG32118 - http://flybase.org/reports/FBgn0052118 protein_coding_gene - - - CG32118 - - 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0005034 er erupt http://flybase.org/reports/FBgn0005034 - gene - - - er - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "eye-antennal disc,eye,ommatidium" FBgn0020355 anon-2G10 anon-2G10 http://flybase.org/reports/FBgn0020355 - gene - - - "2G10, anon-2G10" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0261608 RpL37A Ribosomal protein L37A http://flybase.org/reports/FBgn0261608 protein_coding_gene "structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR002674, InterPro:IPR011331 structural constituent of ribosome ; GO:0003735 | traceable author statement" "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR002674, InterPro:IPR011331, InterPro:IPR011332 cytoplasmic translation ; GO:0002181 | traceable author statement" "ribosome ; GO:0005840 | inferred from electronic annotation with InterPro:IPR002674, InterPro:IPR011331 cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement" "CG5827, RpL37A, M(2)25C, L37A, RpL37a, DmL37a, BcDNA:RH41593, BcDNA:RE23595, M(2)S1, l(2)25Cb, chr2L:5071724..5071820" "IPR002674:Ribosomal protein L37ae, IPR011331:Ribosomal protein L37ae/L37e, IPR011332:Zinc-binding ribosomal protein" CG5827 27-Aug-18 DroID_v2018_08 Drer\zgc:171772 "Scer\RPL43A, Scer\RPL43B" Cele\rpl-43 Xtro\rpl37a Mmus\Rpl37a Hsap\RPL37A adult stage DRSC02899 IEK -2.225551478 -1.85433955 -1.508742041 -2.806904876 -0.293015328 2.057932251 FBgn0038474 mRpS11 mitochondrial ribosomal protein S11 http://flybase.org/reports/FBgn0038474 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement mRNA 5'-UTR binding ; GO:0048027 | inferred from biological aspect of ancestor with PANTHER:PTN000204884 structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:P82912 small ribosomal subunit rRNA binding ; GO:0070181 | inferred from biological aspect of ancestor with PANTHER:PTN000204884 structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:P82911 "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000462 | inferred from biological aspect of ancestor with PANTHER:PTN000204884 mitochondrial translation ; GO:0032543 | inferred from sequence or structural similarity with UniProtKB:P82911 mitochondrial translation ; GO:0032543 | traceable author statement translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:P82912 ribosomal small subunit assembly ; GO:0000028 | inferred from biological aspect of ancestor with PANTHER:PTN000204884" mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:P82911 mitochondrial small ribosomal subunit ; GO:0005763 | traceable author statement mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:P82912 "MRP-S11, CG5184, BcDNA:RH70248, mRpS11, GH1" IPR001971:Ribosomal protein S11 CG5184 27-Aug-18 DroID_v2018_08 "Drer\rps14, Drer\mrps11" "Scer\MRPS18, Scer\RPS14B, Scer\RPS14A" "Cele\rps-14, Cele\mrps-11" Xtro\mrps11 "Mmus\Rps14, Mmus\Mrps11" "Hsap\MRPS11, Hsap\RPS14" FBgn0264575 Egfr::Hsap\EGFR - http://flybase.org/reports/FBgn0264575 engineered_fusion_gene - - - Egfr::Hsap\EGFR - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0028833 Dak1 Dak1 http://flybase.org/reports/FBgn0028833 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000850 cytidylate kinase activity ; GO:0004127 | inferred from direct assay uridylate kinase activity ; GO:0009041 | inferred from direct assay pyrimidine nucleotide biosynthetic process ; GO:0006221 | inferred from electronic annotation with InterPro:IPR006266 'de novo' pyrimidine nucleobase biosynthetic process ; GO:0006207 | inferred from sequence or structural similarity with SGD:S000001507 nucleobase-containing compound metabolic process ; GO:0006139 | inferred from sequence or structural similarity with SGD:S000001507 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000001507 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000001507 "CG6092, Dak1, Dm.UMP-CMP kinase, dak1, Dak1L, anon-WO0118547.320" "IPR000850:Adenylate kinase/UMP-CMP kinase, IPR006266:UMP-CMP kinase, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR033690:Adenylate kinase, conserved site" CG6092 27-Aug-18 DroID_v2018_08 "Drer\ak5l, Drer\ak1, Drer\cmpk, Drer\ak5, Drer\si:ch211-199m3.4" Scer\URA6 "Cele\F38E11.6, Cele\F40F8.1, Cele\F38B2.4, Cele\C29F7.3" "Xtro\ak1, Xtro\cmpk1" "Mmus\Cmpk1, Mmus\Ak5, Mmus\Ak9, Mmus\Ak1, Mmus\Ak8" "Hsap\AK9, Hsap\CMPK1, Hsap\AK1, Hsap\AK5" "viable,fertile" FBgn0024352 Stip1 Hsp70/Hsp90 organizing protein http://flybase.org/reports/FBgn0024352 FBgn0022263 protein_coding_gene - - - "dHop, dmSTI1, EP(2)0418, dhop, dSTI1, l(2)k00616, Sti1, CG2720, Hop, HOP, hop" "IPR006636:Heat shock chaperonin-binding, IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat, IPR001440:Tetratricopeptide repeat 1" CG2720 27-Aug-18 DroID_v2018_08 "Drer\sgut1, Drer\stip1, Drer\ttc12, Drer\si:dkey-33c12.4, Drer\zgc:123010" Scer\STI1 Cele\sti-1 "Xtro\sugt1, Xtro\stip1" "Mmus\Sugt1, Mmus\Stip1, Mmus\Spata16, Mmus\Ttc12" "Hsap\SPATA16, Hsap\SUGT1, Hsap\TTC12, Hsap\STIP1, Hsap\TTC28, Hsap\TTC31" "lethal,recessive,wild-type,viable" FBgn0032350 CG6287 - http://flybase.org/reports/FBgn0032350 protein_coding_gene "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor ; GO:0016616 | inferred from electronic annotation with InterPro:IPR006139 NAD binding ; GO:0051287 | inferred from electronic annotation with InterPro:IPR006139, InterPro:IPR006140" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006139, InterPro:IPR006140" - "CG6287, GH26" "IPR006139:D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain, IPR006140:D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain, IPR016040:NAD(P)-binding domain, IPR029752:D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1" CG6287 27-Aug-18 DroID_v2018_08 "Drer\zgc:136929, Drer\ctbp2a, Drer\ctbp1, Drer\phgdh" "Scer\SER3, Scer\SER33" "Cele\ctbp-1, Cele\C31C9.2" Xtro\phgdh "Mmus\Ctbp2, Mmus\Phgdh, Mmus\Ctbp1" "Hsap\PHGDH, Hsap\CTBP1, Hsap\CTBP2" viable FBgn0004490 don-giovanni don giovanni http://flybase.org/reports/FBgn0004490 - gene - negative regulation of female receptivity ; GO:0007621 | traceable author statement female courtship behavior ; GO:0008050 | non-traceable author statement - "don-giovanni, dg" - - 27-Aug-18 DroID_v2018_08 - - - - - - "courtship behavior defective,male" FBgn0024607 olfJ147 olfactory J147 http://flybase.org/reports/FBgn0024607 - gene - - - olfJ147 - - 27-Aug-18 DroID_v2018_08 - - - - - - smell perception defective FBgn0086384 Mer Merlin http://flybase.org/reports/FBgn0086384 protein_coding_gene actin binding ; GO:0003779 | inferred from electronic annotation with InterPro:IPR008954 cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with sav protein binding ; GO:0005515 | inferred from physical interaction with arm inferred from physical interaction with Moe protein binding ; GO:0005515 | inferred from physical interaction with ex "negative regulation of organ growth ; GO:0046621 | inferred from mutant phenotype olfactory behavior ; GO:0042048 | inferred from mutant phenotype negative regulation of glial cell proliferation ; GO:0060253 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype negative regulation of cell proliferation ; GO:0008285 | inferred from mutant phenotype negative regulation of cell proliferation ; GO:0008285 | inferred from genetic interaction with ex regulation of compound eye retinal cell programmed cell death ; GO:0046669 | inferred from mutant phenotype meiotic chromosome separation ; GO:0051307 | inferred from mutant phenotype endocytic recycling ; GO:0032456 | inferred from genetic interaction with ex compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from genetic interaction with ex regulation of apoptotic process ; GO:0042981 | inferred from genetic interaction with ex decapentaplegic signaling pathway ; GO:0008101 | inferred from genetic interaction with dpp hippo signaling ; GO:0035329 | inferred from genetic interaction with ex, hpo axis specification ; GO:0009798 | inferred from mutant phenotype pole plasm mRNA localization ; GO:0019094 | inferred from mutant phenotype protein localization to plasma membrane ; GO:0072659 | inferred from mutant phenotype cell cycle arrest ; GO:0007050 | inferred from genetic interaction with ex regulation of cell proliferation ; GO:0042127 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with crb negative regulation of organ growth ; GO:0046621 | inferred from genetic interaction with ex male meiosis cytokinesis ; GO:0007112 | inferred from mutant phenotype regulation of cell differentiation ; GO:0045595 | inferred from genetic interaction with ex negative regulation of cell proliferation ; GO:0008285 | inferred from mutant phenotype inferred from genetic interaction with ex sperm individualization ; GO:0007291 | inferred from mutant phenotype cell-cell signaling ; GO:0007267 | inferred from expression pattern regulation of hippo signaling ; GO:0035330 | inferred from mutant phenotype regulation of cell growth ; GO:0001558 | inferred from expression pattern spermatogenesis ; GO:0007283 | inferred from mutant phenotype regulation of signal transduction ; GO:0009966 | inferred from genetic interaction with ex positive regulation of protein phosphorylation ; GO:0001934 | inferred from direct assay positive regulation of phosphorylation ; GO:0042327 | inferred from genetic interaction with ex endocytosis ; GO:0006897 | inferred from expression pattern" "extrinsic component of membrane ; GO:0019898 | inferred from electronic annotation with InterPro:IPR000798, InterPro:IPR011174, InterPro:IPR011259 cytoskeleton ; GO:0005856 | inferred from electronic annotation with InterPro:IPR000299 cytoplasm ; GO:0005737 | inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay Kibra-Ex-Mer complex ; GO:0036375 | inferred from direct assay apical plasma membrane ; GO:0016324 | inferred from direct assay adherens junction ; GO:0005912 | inferred from direct assay Nebenkern ; GO:0016006 | inferred from direct assay fusome ; GO:0045169 | NOT inferred from direct assay membrane ; GO:0016020 | inferred from direct assay" "mer, Mer, BG01543, CG14228, Dmerlin, EMR2, Emr2, D-Mer, NF2" "IPR011993:PH domain-like, IPR011259:Ezrin/radixin/moesin, C-terminal, IPR011174:Ezrin/radixin/moesin, IPR008954:Moesin tail domain, IPR000798:Ezrin/radixin/moesin-like, IPR000299:FERM domain, IPR014352:FERM/acyl-CoA-binding protein, 3-helical bundle, IPR015788:Moesin/ezrin/radixin homologue 2, IPR018979:FERM, N-terminal, IPR018980:FERM, C-terminal PH-like domain, IPR019748:FERM central domain, IPR019749:Band 4.1 domain, IPR029071:Ubiquitin-related domain" CG14228 27-Aug-18 DroID_v2018_08 "Drer\ezrb, Drer\ccdc120, Drer\si:ch211-220f12.1, Drer\nf2b, Drer\zgc:153953, Drer\msnb, Drer\msna, Drer\ezra, Drer\si:ch211-169p10.1, Drer\nf2a, Drer\si:ch211-163l21.4, Drer\frmd4bb" - "Cele\nfm-1, Cele\erm-1" "Xtro\msn, Xtro\ezr, Xtro\frmd4a, Xtro\frmd4b, Xtro\nf2, Xtro\rdx" "Mmus\Rdx, Mmus\Nf2, Mmus\Frmd4a, Mmus\5730559C18Rik, Mmus\Msn, Mmus\Ezr, Mmus\Frmd4b, Mmus\Ccdc120" "Hsap\CCDC120, Hsap\EZR, Hsap\FRMD4B, Hsap\RDX, Hsap\MSN, Hsap\C1orf106, Hsap\FRMD4A, Hsap\NF2" FBgn0005335 podK podoptera of Kellen Piternick http://flybase.org/reports/FBgn0005335 - gene - - - "pod-K, podK" - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing,eye,postvertical bristle" FBgn0011853 tRNA:Glu-CTC-3-6 transfer RNA:Glutamic acid-CTC 3-6 http://flybase.org/reports/FBgn0011853 "FBgn0003768, FBgn0003772, FBgn0011846, FBgn0052325, FBgn0060248" tRNA_gene GAG codon-amino acid adaptor activity ; GO:0033460 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033460 cytosol ; GO:0005829 | inferred by curator from GO:0033460 "AE002584.trna8-GluCTC, tRNA:E4, tRNA:E:CTC:AE002584-f, tRNA:glu4:62Ac, CR32325, tRNA:Glu, chr3L.trna8-GluCTC, tRNA:Glu-CTC-3-6, tRNA:E4:62Ac, tRNA-Glu-CTC-3-6, GAG" - CR32325 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0058086 CG40086 - http://flybase.org/reports/FBgn0058086 protein_coding_gene - - - CG40086 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060688 l(3)S074510b lethal (3) S074510b http://flybase.org/reports/FBgn0060688 gene - - - "0745/10, l(3)S074510b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0041175 Ubx::Hrob\Lox2 Ubx::Hrob\Lox2 http://flybase.org/reports/FBgn0041175 engineered_fusion_gene - - - Ubx::Hrob\Lox2 - - 27-Aug-18 DroID_v2018_08 - - - - - - "leg,ectopic,antenna,haltere,wing,embryonic epidermis,abdominal 1 ventral denticle belt,Kolbchen" FBgn0014043 Su(tor)2-15 Su(tor)2-15 http://flybase.org/reports/FBgn0014043 - gene - - - Su(tor)2-15 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0031443 Prosbeta4R2 Proteasome beta4 subunit-related 2 http://flybase.org/reports/FBgn0031443 protein_coding_gene "threonine-type endopeptidase activity ; GO:0004298 | inferred from electronic annotation with InterPro:IPR001353, InterPro:IPR023333 molecular_function ; GO:0003674 | no biological data available" "proteolysis involved in cellular protein catabolic process ; GO:0051603 | inferred from electronic annotation with InterPro:IPR001353, InterPro:IPR016050" "proteasome core complex ; GO:0005839 | inferred from electronic annotation with InterPro:IPR001353, InterPro:IPR016050" "anon-WO0140519.122, Prosbeta4R2, CG17302, beta4R2" "IPR001353:Proteasome, subunit alpha/beta, IPR023333:Proteasome B-type subunit, IPR016050:Proteasome beta-type subunit, conserved site, IPR029055:Nucleophile aminohydrolases, N-terminal" CG17302 27-Aug-18 DroID_v2018_08 Drer\psmb2 Scer\PRE1 Cele\pbs-4 Xtro\psmb2 Mmus\Psmb2 Hsap\PSMB2 viable FBgn0260574 MENE-GG12 - http://flybase.org/reports/FBgn0260574 gene - - - MENE-GG12 - - 27-Aug-18 DroID_v2018_08 - - - - - - "eye disc,somatic clone" FBgn0265199 CG44259 - http://flybase.org/reports/FBgn0265199 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44259 - CG44259 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259641 B0432 - http://flybase.org/reports/FBgn0259641 gene - - - B0432 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible wing FBgn0038741 CG17186 - http://flybase.org/reports/FBgn0038741 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - CG17186 IPR013087:Zinc finger C2H2-type CG17186 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0035462 IntS10 Integrator 10 http://flybase.org/reports/FBgn0035462 protein_coding_gene molecular_function ; GO:0003674 | no biological data available snRNA processing ; GO:0016180 | inferred from sequence or structural similarity with HGNC:25548 integrator complex ; GO:0032039 | inferred from sequence or structural similarity with HGNC:25548 "IntS10, Int10, CG1120" "IPR016024:Armadillo-type fold, IPR011990:Tetratricopeptide-like helical domain, IPR026164:Integrator complex subunit 10" CG1120 27-Aug-18 DroID_v2018_08 Drer\ints10 - "Cele\srh-166, Cele\srh-251, Cele\srh-234, Cele\srh-233, Cele\srh-194, Cele\srh-69, Cele\srh-258, Cele\srh-292, Cele\srh-207, Cele\srh-286, Cele\srh-145, Cele\srh-217, Cele\srh-236, Cele\srh-135, Cele\srh-243, Cele\srh-287, Cele\srh-248, Cele\srh-223, Cele\srh-281, Cele\srh-147, Cele\srh-208, Cele\srh-219, Cele\srh-195, Cele\srh-170, Cele\srh-192, Cele\srh-277, Cele\srh-308, Cele\srh-142, Cele\srh-199, Cele\srh-289, Cele\srh-204, Cele\srh-215, Cele\srh-201, Cele\srh-187, Cele\srh-214, Cele\srh-179, Cele\srh-216, Cele\srh-67, Cele\srh-133, Cele\srh-244, Cele\srh-212, Cele\srh-132, Cele\srh-257, Cele\srh-265, Cele\srh-206, Cele\srh-274, Cele\srh-235, Cele\srh-295, Cele\srh-134, Cele\srh-182, Cele\srh-246" Xtro\ints10 Mmus\Ints10 Hsap\INTS10 "viable,visible" trichogen cell FBgn0085157 l(3)S000718 l(3)S000718 http://flybase.org/reports/FBgn0085157 gene - - - l(3)S000718 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034127 CG7848 - http://flybase.org/reports/FBgn0034127 protein_coding_gene "NAD binding ; GO:0051287 | inferred from electronic annotation with InterPro:IPR012302 malate dehydrogenase (decarboxylating) (NAD+) activity ; GO:0004471 | inferred from electronic annotation with InterPro:IPR001891, InterPro:IPR012301, InterPro:IPR012302 malate dehydrogenase (decarboxylating) (NADP+) activity ; GO:0004473 | inferred from biological aspect of ancestor with PANTHER:PTN000601052" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001891, InterPro:IPR012301, InterPro:IPR012302 pyruvate metabolic process ; GO:0006090 | inferred from biological aspect of ancestor with PANTHER:PTN000601050 malate metabolic process ; GO:0006108 | inferred from biological aspect of ancestor with PANTHER:PTN000601050" mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN001157886 CG7848 "IPR001891:Malic oxidoreductase, IPR012301:Malic enzyme, N-terminal domain, IPR012302:Malic enzyme, NAD-binding, IPR016040:NAD(P)-binding domain" CG7848 27-Aug-18 DroID_v2018_08 "Drer\me2, Drer\me3, Drer\me1, Drer\LOC101882012" Scer\MAE1 Cele\men-1 "Xtro\me2, Xtro\me3" "Mmus\Me3, Mmus\Me1, Mmus\Me2" "Hsap\ME3, Hsap\ME1, Hsap\ME2" FBgn0267983 lncRNA:CR46250 - http://flybase.org/reports/FBgn0267983 non_protein_coding_gene - - - CR46250 - CR46250 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262200 mir-962 mir-962 stem loop http://flybase.org/reports/FBgn0262200 miRNA_gene - "regulation of feeding behavior ; GO:0060259 | inferred from genetic interaction with mir-959, mir-960, mir-961 immune response ; GO:0006955 | inferred from genetic interaction with mir-959, mir-960, mir-961" - "dme-mir-962, 962, mir-962, CR42907, miR-962" - CR42907 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0266853 lncRNA:CR45314 - http://flybase.org/reports/FBgn0266853 non_protein_coding_gene - - - CR45314 - CR45314 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051321 CG31321 - http://flybase.org/reports/FBgn0051321 protein_coding_gene molecular_function ; GO:0003674 | no biological data available transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011701 cellular_component ; GO:0005575 | no biological data available "BcDNA:RH31685, CG31321" "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG31321 27-Aug-18 DroID_v2018_08 "Drer\slc46a1, Drer\si:ch211-262i1.4, Drer\hiat1b, Drer\slc46a3, Drer\LOC100002406, Drer\si:dkey-5g14.1, Drer\LOC557306, Drer\zgc:174356, Drer\hiat1a" Scer\YJL163C "Cele\F40F9.5, Cele\Y4C6B.5, Cele\Y43F8A.5" "Xtro\slc46a1, Xtro\mfsd14a, Xtro\slc46a2, Xtro\mfsd14b" "Mmus\Slc46a1, Mmus\Slc46a3, Mmus\Mfsd14a, Mmus\Slc46a2, Mmus\Mfsd14b" "Hsap\MFSD14A, Hsap\SLC46A3, Hsap\SLC46A1, Hsap\MFSD14B, Hsap\SLC46A2" "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0039838 CG3669 - http://flybase.org/reports/FBgn0039838 protein_coding_gene carbonate dehydratase activity ; GO:0004089 | inferred from electronic annotation with InterPro:IPR018338 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR018338 one-carbon metabolic process ; GO:0006730 | inferred from electronic annotation with InterPro:IPR018338 - CG3669 "IPR001148:Alpha carbonic anhydrase, IPR018338:Carbonic anhydrase, alpha-class, conserved site, IPR023561:Carbonic anhydrase, alpha-class" CG3669 27-Aug-18 DroID_v2018_08 "Drer\ca12, Drer\zgc:153760, Drer\car15, Drer\ca7, Drer\si:ch211-173d10.4, Drer\ca15b, Drer\ca10a, Drer\ptprga, Drer\ca9, Drer\ca6, Drer\ca15c, Drer\ca10b, Drer\ca2, Drer\ca4a, Drer\ca8, Drer\ca4c, Drer\ca5a, Drer\ca16b, Drer\ca14, Drer\ca15a, Drer\cahz, Drer\ca4b" - "Cele\cah-6, Cele\cah-5, Cele\cah-3, Cele\cah-4" "Xtro\LOC779564, Xtro\ca14, Xtro\ca8, Xtro\ca2, Xtro\ca7, Xtro\ca4, Xtro\ca1, Xtro\ca5b, Xtro\ca6, Xtro\ca3, Xtro\ca11, Xtro\ca10, Xtro\ca12" "Mmus\Car5b, Mmus\Car1, Mmus\Car15, Mmus\Car3, Mmus\Car6, Mmus\Car7, Mmus\Car2, Mmus\Car10, Mmus\Car14, Mmus\Car13, Mmus\Car9, Mmus\Car11, Mmus\Car12, Mmus\Car8, Mmus\Car4, Mmus\Ptprg, Mmus\Car5a" "Hsap\CA4, Hsap\CA5A, Hsap\CA1, Hsap\CA9, Hsap\CA12, Hsap\CA11, Hsap\CA3, Hsap\CA13, Hsap\CA5B, Hsap\CA14, Hsap\CA2, Hsap\CA8, Hsap\CA10, Hsap\CA7, Hsap\CA6, Hsap\PTPRG" FBgn0267459 lncRNA:CR45809 - http://flybase.org/reports/FBgn0267459 non_protein_coding_gene - - - CR45809 - CR45809 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260012 pds5 precocious dissociation of sisters 5 http://flybase.org/reports/FBgn0260012 protein_coding_gene - sleep ; GO:0030431 | inferred from expression pattern karyosome formation ; GO:0030717 | inferred from mutant phenotype chromosome segregation ; GO:0007059 | inferred from mutant phenotype sister chromatid cohesion ; GO:0007062 | inferred from mutant phenotype mitotic sister chromatid cohesion ; GO:0007064 | inferred from biological aspect of ancestor with PANTHER:PTN000292173 mitotic cohesin unloading ; GO:0061781 | inferred from mutant phenotype DNA repair ; GO:0006281 | inferred from biological aspect of ancestor with PANTHER:PTN000292173 chromatin ; GO:0000785 | inferred from biological aspect of ancestor with PANTHER:PTN000292173 polytene chromosome ; GO:0005700 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "Pds5, dPds5, CG17509, l(2)k13312, anon-WO0118547.183, pds5, PDS5" "IPR016024:Armadillo-type fold, IPR013763:Cyclin-like, IPR011989:Armadillo-like helical" CG17509 27-Aug-18 DroID_v2018_08 "Drer\pds5a, Drer\pds5b" Scer\PDS5 Cele\evl-14 "Xtro\pds5a, Xtro\pds5b" "Mmus\Pds5b, Mmus\Pds5a" "Hsap\PDS5B, Hsap\PDS5A" FBgn0065418 l(2)SH1531 lethal (2) SH1531 http://flybase.org/reports/FBgn0065418 gene - - - "l(2)SH1531, l(2)SH2 1531" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0015904 ara araucan http://flybase.org/reports/FBgn0015904 FBgn0014195 protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay" "equator specification ; GO:0045317 | traceable author statement negative regulation of growth ; GO:0045926 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype notum cell fate specification ; GO:0035310 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | non-traceable author statement imaginal disc-derived wing vein specification ; GO:0007474 | inferred from genetic interaction with rho inferred from genetic interaction with caup muscle cell fate commitment ; GO:0042693 | inferred from genetic interaction with caup" nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:8632 inferred by curator from GO:0003705 "ara, Iro-C, IRO-C, iro, Iro, iro-C, CG10571, Ara, IroC" "IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR008422:Homeobox KN domain, IPR017970:Homeobox, conserved site, IPR015943:WD40/YVTN repeat-like-containing domain, IPR003893:Iroquois-class homeodomain protein" CG10571 27-Aug-18 DroID_v2018_08 "Drer\irx1a, Drer\irx4a, Drer\meis3, Drer\irx5a, Drer\pknox1.1, Drer\irx1b, Drer\pknox1.2, Drer\mkxa, Drer\irx5b, Drer\pknox2, Drer\irx6a, Drer\irx2a, Drer\meis1a, Drer\meis2a, Drer\irx3a, Drer\irx4b, Drer\tgif1, Drer\irx3b, Drer\irx7, Drer\meis2b" "Scer\TOS8, Scer\HMLALPHA2, Scer\MATALPHA2, Scer\CUP9, Scer\HMRA2" Cele\irx-1 "Xtro\irx5, Xtro\meis3, Xtro\tgif2, Xtro\irx4, Xtro\tgif1, Xtro\irx2, Xtro\irx3, Xtro\meis1, Xtro\irx1, Xtro\mkx, Xtro\meis2, Xtro\pknox2" "Mmus\Irx1, Mmus\Irx2, Mmus\Meis2, Mmus\Irx5, Mmus\Meis1, Mmus\Pknox1, Mmus\Tgif1, Mmus\Irx6, Mmus\Irx4, Mmus\Pknox2, Mmus\Tgif2lx1, Mmus\Meis3, Mmus\Tgif2lx2, Mmus\Tgif2, Mmus\Irx3, Mmus\Mkx" "Hsap\IRX6, Hsap\MEIS1, Hsap\TGIF2, Hsap\IRX4, Hsap\IRX2, Hsap\IRX5, Hsap\TGIF2LY, Hsap\MKX, Hsap\TGIF2-C20orf24, Hsap\PKNOX1, Hsap\IRX3, Hsap\PKNOX2, Hsap\TGIF1, Hsap\TGIF2LX, Hsap\MEIS2, Hsap\IRX1" " larval stage | third instar , larval stage , embryonic stage -- adult stage , embryonic stage | late , larval stage | second instar , embryonic stage | stage >=11 " " wing vein L5

, dorsal metathoracic disc

, imaginal disc

, embryonic/larval proventriculus

, wing vein L1

, procephalic segment

, mesothoracic pleurum

, tegula

, epidermis | lateral

, alula

, ventral nerve cord

, wing vein L3

" "lethal,recessive,neuroanatomy defective,viable,visible,partially lethal - majority die,female sterile,male sterile,planar polarity defective,lethal - all die before end of larval stage,some die during larval stage,some die during pupal stage" "wing vein L5,alula,dorsal multidendritic neuron ddaD,abdominal anterior ventral multidendritic neuron vdaa,wing,macrochaeta,macrochaeta & adult thorax,eye,macrochaeta & scutum,microchaeta,mesothoracic segment,notopleural suture,scutellum,wing vein L1,wing vein L3,sensillum campaniformium of dorsal radius,campaniform sensillum of anterior crossvein,twin sensillum of margin 1,twin sensillum of margin 2,wing hinge,axillary sclerite,dorsal margin photoreceptor,ectopic,ommatidium,maxillary palpus,rostral membrane,adult cuticle,eye disc,somatic clone,photoreceptor cell,antenna,arista,vibrissae,scutum & microchaeta | medial-537.4,wing vein L2,posterior supraalar bristle,anterior supraalar bristle,posterior scutellar bristle,wing vein,sense organ & wing | anteriorC-765,anterior postalar bristle,mesothoracic tergum,dorsal,ventral,embryonic/larval brain" FBgn0063903 Neurodegeneration-9 Neurodegeneration 9 http://flybase.org/reports/FBgn0063903 gene - - - "ND10, Neurodegeneration-9, ND9" - - 27-Aug-18 DroID_v2018_08 - - - - - - central nervous system FBgn0026244 fret free thinker http://flybase.org/reports/FBgn0026244 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "thag, fret" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0028629 ksh-18 ksh-18 http://flybase.org/reports/FBgn0028629 gene - - - ksh-18 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0261692 T:CBD-WASp Cdc42-binding domain of WASp http://flybase.org/reports/FBgn0261692 engineered_tag - - - "T:CBD-WASp, T:CBD" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030952 CG12609 - http://flybase.org/reports/FBgn0030952 protein_coding_gene "transcription coactivator activity ; GO:0003713 | inferred from biological aspect of ancestor with PANTHER:PTN001073606 basal RNA polymerase II transcription machinery binding ; GO:0001099 | inferred from biological aspect of ancestor with PANTHER:PTN001073606 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN001073606" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from biological aspect of ancestor with PANTHER:PTN001073606" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001073606 CG12609 IPR006578:MADF domain CG12609 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0035508 CG15005 - http://flybase.org/reports/FBgn0035508 protein_coding_gene - - - CG15005 IPR032059:Mucin-like domain CG15005 27-Aug-18 DroID_v2018_08 "Drer\si:ch73-103b11.2, Drer\triobpa, Drer\triobpb" - Cele\hpo-34 "Xtro\triobp, Xtro\mprip" "Mmus\Triobp, Mmus\Mprip" Hsap\MAGEC1 viable FBgn0050342 Prp38 pre-mRNA processing factor 38 http://flybase.org/reports/FBgn0050342 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Mfap1 "regulation of G2/M transition of mitotic cell cycle ; GO:0010389 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 mRNA splicing, via spliceosome ; GO:0000398 | inferred from mutant phenotype" protein complex ; GO:0043234 | inferred from physical interaction with Mfap1 precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "CG8054, prp38, dprp38, Prp38, CG30342" "IPR005037:Pre-mRNA-splicing factor 38, IPR024767:Pre-mRNA-splicing factor 38, C-terminal" CG30342 27-Aug-18 DroID_v2018_08 Drer\prpf38a Scer\PRP38 Cele\prp-38 Xtro\prpf38a Mmus\Prpf38a Hsap\PRPF38A "increased cell death,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage,viable,lethal - all die before end of first instar larval stage,recessive,some die during first instar larval stage" "wing disc,somatic clone,wing pouch" FBgn0002499 l(3)SG60 lethal (3) SG60 http://flybase.org/reports/FBgn0002499 FBgn0004729 gene - - - "l(3)2306, l(3)ds13, l(3)B13, l(3)SG60" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" imaginal disc FBgn0052847 CG32847 - http://flybase.org/reports/FBgn0052847 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 ubiquitin protein ligase activity involved in ERAD pathway ; GO:1904264 | inferred from biological aspect of ancestor with PANTHER:PTN000267874 ubiquitin-like protein conjugating enzyme binding ; GO:0044390 | inferred from biological aspect of ancestor with PANTHER:PTN000267874 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:10068 ER-associated misfolded protein catabolic process ; GO:0071712 | inferred from biological aspect of ancestor with PANTHER:PTN000267874 protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with HGNC:10068 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN000267874 Derlin-1 retrotranslocation complex ; GO:0036513 | inferred from biological aspect of ancestor with PANTHER:PTN000267874 CG32847 "IPR001841:Zinc finger, RING-type, IPR017907:Zinc finger, RING-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG32847 27-Aug-18 DroID_v2018_08 "Drer\rnf5, Drer\rnf185" Scer\SLX8 Cele\rnf-5 "Xtro\rnf185, Xtro\rnf5" "Mmus\Rnf185, Mmus\Rnf5, Mmus\Trim26" "Hsap\RNF185, Hsap\TRIM26, Hsap\RNF5" viable DRSC22901 K 0.516893721 -1.482651924 0.562264829 -0.377019019 1.572156915 0.717834331 FBgn0069145 mcl(3)Z4085 mcl(3)Z4085 http://flybase.org/reports/FBgn0069145 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z4085 - - 27-Aug-18 DroID_v2018_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0024869 l(2)k14209 lethal (2) k14209 http://flybase.org/reports/FBgn0024869 - gene - - - l(2)k14209 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266197 asRNA:CR44892 - http://flybase.org/reports/FBgn0266197 non_protein_coding_gene - - - CR44892 - CR44892 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033891 CG8067 - http://flybase.org/reports/FBgn0033891 protein_coding_gene methyltransferase activity ; GO:0008168 | inferred from electronic annotation with InterPro:IPR013216 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR013216 cellular_component ; GO:0005575 | no biological data available CG8067 "IPR013216:Methyltransferase type 11, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG8067 27-Aug-18 DroID_v2018_08 Drer\ndufaf5 - Cele\K09E4.3 Xtro\ndufaf5 Mmus\Ndufaf5 Hsap\NDUFAF5 viable FBgn0263126 Ubx::Csal\abd-A - http://flybase.org/reports/FBgn0263126 engineered_fusion_gene - - - "Ubx::Zzzz\Cs-abd-A, Ubx::Csal\abd-A" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0050284 CG30284 - http://flybase.org/reports/FBgn0050284 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs16b04, BcDNA:AT12437, BcDNA:AT22714, CG30284" IPR031968:VASt domain CG30284 27-Aug-18 DroID_v2018_08 "Drer\gramd1c, Drer\gramd2a, Drer\gramd1ba, Drer\gramd1bb, Drer\gramd1a" "Scer\LAM4, Scer\LAM6, Scer\LAM5, Scer\YSP2" Cele\ZC328.3 "Xtro\gramd1c, Xtro\gramd1b, Xtro\gramd3" "Mmus\Gramd1a, Mmus\Gramd1b, Mmus\Gramd3, Mmus\Gramd1c, Mmus\Gramd2" "Hsap\GRAMD3, Hsap\GRAMD2, Hsap\GRAMD1A, Hsap\GRAMD1C, Hsap\GRAMD1B" viable FBgn0267290 lncRNA:CR45726 - http://flybase.org/reports/FBgn0267290 non_protein_coding_gene - - - CR45726 - CR45726 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0053322 CG33322 - http://flybase.org/reports/FBgn0053322 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "38E.23, CG9329, BcDNA:AT04844, CG33322" - CG33322 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" FBgn0001740 l(1)HM10 lethal (1) HM10 http://flybase.org/reports/FBgn0001740 - gene - - - l(1)HM10 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,cold sensitive,female semi-sterile,visible,tumorigenic" "wing,adult abdomen" FBgn0044092 E(rst)D19 E(rst)D19 http://flybase.org/reports/FBgn0044092 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "D19, E(rst)D19" - - 27-Aug-18 DroID_v2018_08 - - - - - - viable "eye,cone cell,primary pigment cell,ectopic" FBgn0045064 bwa brain washing http://flybase.org/reports/FBgn0045064 protein_coding_gene ceramidase activity ; GO:0017040 | NOT inferred from mutant phenotype ceramidase activity ; GO:0017040 | inferred from sequence or structural similarity with UniProtKB:Q8R4X1 ceramidase activity ; GO:0017040 | inferred from direct assay brain development ; GO:0007420 | NOT inferred from mutant phenotype ceramide catabolic process ; GO:0046514 | inferred from sequence or structural similarity with UniProtKB:Q8R4X1 ceramide catabolic process ; GO:0046514 | inferred from direct assay regulation of lipid metabolic process ; GO:0019216 | inferred from sequence or structural similarity with UniProtKB:Q8R4X1 brain development ; GO:0007420 | inferred from mutant phenotype sphingolipid metabolic process ; GO:0006665 | inferred from sequence or structural similarity with UniProtKB:Q8R4X1 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR008901 endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with UniProtKB:Q8R4X1 "CG13969, 38B.6, bwa, dacer" IPR008901:Ceramidase CG13969 27-Aug-18 DroID_v2018_08 "Drer\acer2, Drer\acer3, Drer\acer1" "Scer\YPC1, Scer\YDC1" Cele\W02F12.2 "Xtro\acer2, Xtro\acer3, Xtro\acer1" "Mmus\Acer1, Mmus\Acer3, Mmus\Acer2" "Hsap\ACER3, Hsap\ACER1, Hsap\ACER2" "viable,fertile,developmental rate defective,long lived,oxidative stress response defective" "mushroom body beta-lobe,adult mushroom body beta'-lobe,ellipsoid body" FBgn0037028 CG3618 - http://flybase.org/reports/FBgn0037028 protein_coding_gene - cell adhesion ; GO:0007155 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype actin filament organization ; GO:0007015 | inferred from mutant phenotype - "GYCb100B, CG3618" IPR015943:WD40/YVTN repeat-like-containing domain CG3618 27-Aug-18 DroID_v2018_08 "Drer\fam234a, Drer\fam234b" - - Xtro\fam234a "Mmus\Fam234a, Mmus\Fam234b" "Hsap\FAM234B, Hsap\FAM234A" "viable,fertile" FBgn0062594 Mod(var)1540 Mod(var)1540 http://flybase.org/reports/FBgn0062594 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1540, Mod(var)1540" - - 27-Aug-18 DroID_v2018_08 - - - - - - suppressor of variegation FBgn0022754 amputee amputee http://flybase.org/reports/FBgn0022754 - gene - - - amputee - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "leg,femur" FBgn0032072 CG9483 - http://flybase.org/reports/FBgn0032072 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon-WO0140519.161, CG9483" - CG9483 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,some die during pupal stage" FBgn0040281 Aplip1 APP-like protein interacting protein 1 http://flybase.org/reports/FBgn0040281 protein_coding_gene protein kinase binding ; GO:0019901 | inferred from physical interaction with hep MAP-kinase scaffold activity ; GO:0005078 | inferred from physical interaction with UniProtKB:Q23977 kinesin binding ; GO:0019894 | inferred from physical interaction with Klc JUN kinase binding ; GO:0008432 | NOT inferred from sequence alignment with MGI:MGI:1309464 inferred from sequence alignment with MGI:MGI:1926555 inferred from physical interaction with bsk protein binding ; GO:0005515 | inferred from physical interaction with Appl neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype retrograde synaptic vesicle transport ; GO:0048491 | inferred from mutant phenotype axonal transport of mitochondrion ; GO:0019896 | inferred from mutant phenotype regulation of terminal button organization ; GO:2000331 | inferred from mutant phenotype JNK cascade ; GO:0007254 | inferred from sequence alignment with MGI:MGI:1309464 inferred from sequence alignment with MGI:MGI:1926555 anterograde synaptic vesicle transport ; GO:0048490 | inferred from mutant phenotype regulation of JNK cascade ; GO:0046328 | inferred from physical interaction with hep regulation of JNK cascade ; GO:0046328 | inferred from sequence or structural similarity with UniProtKB:Q9WVI9 axon ; GO:0030424 | inferred from direct assay "Jip1/2, APLIP1, aplip1, SP512, CG1200, dp1, ek4, E(Khc)ek4, EK4, Ek4, Aplip1, JIP1, jip1, aplilp1" "IPR001452:SH3 domain, IPR006020:PTB/PI domain, IPR011993:PH domain-like" CG1200 27-Aug-18 DroID_v2018_08 "Drer\mapk8ip1, Drer\mapk8ip2, Drer\mapk8ip1" - Cele\jip-1 "Xtro\mapk8ip1, Xtro\mapk8ip2" "Mmus\Mapk8ip2, Mmus\Mapk8ip1" "Hsap\MAPK8IP2, Hsap\MAPK8IP1" " larval stage--adult stage , adult stage , embryonic stage | mid-late , embryonic stage | late " " head

, embryonic central nervous system

, embryonic brain

" "viable,neuroanatomy defective,paralytic,fertile,posterior,lethal" "NMJ bouton,NMJ bouton | larval stage,axon,mitochondrion,axonFpa2),axonD42" FBgn0000954 fs(2)E1 female sterile (2) E1 http://flybase.org/reports/FBgn0000954 - gene - - - "fs2.1, fs(2)E1" - - 27-Aug-18 DroID_v2018_08 - - - - - - female sterile "egg,gonad,dorsal appendage" FBgn0011208 bob bobble http://flybase.org/reports/FBgn0011208 - gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype karyosome formation ; GO:0030717 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "ms(3)06208, bob" - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,female fertile,male fertile,male sterile,recessive,partially lethal - majority die,meiotic cell cycle defective,lethal,female sterile,germline clone" "Nebenkern,karyosome,germline clone,egg chamber" FBgn0003926 snRNA:U3 small nuclear RNA U3 at 22A http://flybase.org/reports/FBgn0003926 "FBgn0003925, FBgn0051927" snRNA_gene - - - "snRNA[[2]], K7, snRNA:U3, snRNA3, snRNA2, U3snRNA22A, CR31927, U3snRNA, snRNA:U3:22A" - CR31927 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263024 CG43319 - http://flybase.org/reports/FBgn0263024 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "CG43319, CG12879" - CG43319 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0261885 osa osa http://flybase.org/reports/FBgn0261885 protein_coding_gene transcription coactivator activity ; GO:0003713 | contributes_to inferred by curator from GO:0035060 DNA binding ; GO:0003677 | non-traceable author statement DNA binding ; GO:0003677 | inferred from direct assay "chromatin remodeling ; GO:0006338 | inferred from electronic annotation with InterPro:IPR021906 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from mutant phenotype adult chitin-containing cuticle pigmentation ; GO:0048085 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype Wnt signaling pathway ; GO:0016055 | inferred from mutant phenotype photoreceptor cell differentiation ; GO:0046530 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from direct assay positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from physical interaction with ham segment specification ; GO:0007379 | inferred from mutant phenotype imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype regulation of epidermal growth factor receptor signaling pathway ; GO:0042058 | inferred from mutant phenotype wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap neuroblast fate commitment ; GO:0014017 | inferred from mutant phenotype imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype negative regulation of neuroblast proliferation ; GO:0007406 | inferred from genetic interaction with numb inferred from genetic interaction with brat regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from direct assay" nucleus ; GO:0005634 | inferred from direct assay brahma complex ; GO:0035060 | traceable author statement brahma complex ; GO:0035060 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay "OSA, eyelid, osa, Osa, CG7467, eld, en(lz)4F/4H, p300, E(E2F)3C, l(3)04539, l(3)00090, l(3)j9C3, anon-WO0172774.126, anon-WO0118547.314, C819" "IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical, IPR001606:ARID DNA-binding domain, IPR021906:SWI/SNF-like complex subunit BAF250/Osa, IPR033388:SWI/SNF-like complex subunit BAF250, C-terminal" CG7467 27-Aug-18 DroID_v2018_08 "Drer\arid1ab, Drer\arid1aa, Drer\arid5b, Drer\arid3b, Drer\arid1b, Drer\arid3a, Drer\arid3c, Drer\arid4a" "Scer\RSC9, Scer\SWI1, Scer\ECM5" "Cele\arid-1, Cele\cfi-1, Cele\let-526" "Xtro\arid1b, Xtro\arid3b, Xtro\arid3a, Xtro\arid1a" "Mmus\Arid3a, Mmus\Arid3c, Mmus\Arid4a, Mmus\Arid4b, Mmus\Arid5b, Mmus\Arid1b, Mmus\Arid3b, Mmus\Arid5a, Mmus\Arid1a" "Hsap\ARID3C, Hsap\ARID3A, Hsap\ARID1A, Hsap\ARID4A, Hsap\ARID4B, Hsap\ARID5B, Hsap\ARID1B, Hsap\ARID5A, Hsap\ARID3B" " larval stage , embryonic stage | early " " larval salivary gland

,

ubiquitous , morphogenetic furrow | anterior to

, eye disc

, dorsal mesothoracic disc

" DRSC03744 IE -0.083839134 -3.507738129 -0.47039841 1.688272232 FBgn0029809 CG15767 - http://flybase.org/reports/FBgn0029809 protein_coding_gene peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from electronic annotation with InterPro:IPR002130 protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR002130 protein peptidyl-prolyl isomerization ; GO:0000413 | inferred from electronic annotation with InterPro:IPR002130 - CG15767 "IPR002130:Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain, IPR024936:Cyclophilin-type peptidyl-prolyl cis-trans isomerase, IPR029000:Cyclophilin-like domain" CG15767 27-Aug-18 DroID_v2018_08 "Drer\ppifb, Drer\ppid, Drer\ppiaa, Drer\ppifa, Drer\ppiab" "Scer\CPR3, Scer\CPR1" Cele\T22F3.12 "Xtro\ppia, Xtro\ppif" "Mmus\Ranbp2, Mmus\Ppia, Mmus\Ppid, Mmus\Ppif" "Hsap\PPIAL4E, Hsap\PPID, Hsap\PPIA, Hsap\PPIF, Hsap\RANBP2, Hsap\PPIAL4A, Hsap\LOC105371242, Hsap\PPIAL4D, Hsap\PPIAL4G, Hsap\PPIAL4C" viable DRSC29131 K 0.028478082 0.478489976 0.458077061 0.504459433 -1.94110309 0.176577654 FBgn0005022 dkl darker legs http://flybase.org/reports/FBgn0005022 - gene - - - "thl[d], thl-d, dkl" - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,female fertile,poor,visible,reduced,body color defective" "eye,wing,leg,adult thorax,adult abdomen" FBgn0069219 gl(3R)53-6 gl(3R)53-6 http://flybase.org/reports/FBgn0069219 gene molecular_function ; GO:0003674 | no biological data available segment specification ; GO:0007379 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available gl(3R)53-6 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,germline clone,recessive,rescuable maternal effect,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "embryonic head,germline clone,maternal effect,embryonic segment,embryonic abdominal segment" FBgn0032150 CG13123 - http://flybase.org/reports/FBgn0032150 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG13123 "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type" CG13123 27-Aug-18 DroID_v2018_08 Drer\si:dkey-208k4.2 Scer\PZF1 Cele\ZK546.5 - - "Hsap\ZNF112, Hsap\ZBTB24" viable DRSC02219 IE 0.321201511 -1.692175389 -1.716207126 -0.003728123 -0.982427981 0.131021487 FBgn0021808 l(2)k16703 lethal (2) k16703 http://flybase.org/reports/FBgn0021808 - gene - - - l(2)k16703 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0065462 l(2)SH1362 lethal (2) SH1362 http://flybase.org/reports/FBgn0065462 gene - - - "l(2)SH1362, l(2)SH2 1362" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0266123 T:PACT-Plp PACT domain of Plp http://flybase.org/reports/FBgn0266123 engineered_tag - - - "T:PACT-Plp, T:PACT-cp309" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060541 l(3)S099908 lethal (3) S099908 http://flybase.org/reports/FBgn0060541 gene - - - "0999/08, l(3)S099908" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0086129 snama something that sticks like glue http://flybase.org/reports/FBgn0086129 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841, InterPro:IPR001878, InterPro:IPR014891 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001878 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:9889" neurogenesis ; GO:0022008 | inferred from mutant phenotype cell proliferation involved in compound eye morphogenesis ; GO:0035736 | inferred from mutant phenotype apoptotic process ; GO:0006915 | inferred from mutant phenotype protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from sequence or structural similarity with HGNC:9889 nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR014891 cellular_component ; GO:0005575 | no biological data available "CG3231, l(2)rQ313, BcDNA:LD21643, snama, SNAMA, BCDNA:LD21643, mnm, Snama, FBgn0086129" "IPR001878:Zinc finger, CCHC-type, IPR001841:Zinc finger, RING-type, IPR014891:DWNN domain, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR025829:Zinc knuckle CX2CX3GHX4C" CG3231 27-Aug-18 DroID_v2018_08 "Drer\LOC100002202, Drer\si:rp71-45g20.11, Drer\zgc:77614, Drer\LOC561873, Drer\rbbp6, Drer\zgc:91850, Drer\si:dkey-27d5.10, Drer\si:rp71-45g20.10, Drer\LOC100004867, Drer\si:dkey-23f9.8, Drer\LOC100006889, Drer\LOC103911531, Drer\si:dkey-23f9.7, Drer\LOC100329917, Drer\LOC100329755, Drer\LOC100005207, Drer\LOC100536005, Drer\LOC100005013, Drer\si:dkey-23f9.13, Drer\LOC100535429, Drer\si:dkey-27d5.14, Drer\si:busm1-37i06.3, Drer\LOC108179082, Drer\LOC100006815, Drer\LOC101882874, Drer\si:dkey-23f9.6, Drer\si:rp71-45g20.4, Drer\LOC108190973, Drer\LOC100535555, Drer\si:dkey-23f9.11, Drer\LOC100006401, Drer\si:dkey-23f9.12, Drer\LOC100007007, Drer\zgc:174354, Drer\LOC100005157, Drer\LOC103909946, Drer\zgc:173948, Drer\LOC100007069, Drer\si:dkey-27d5.5, Drer\LOC100004392, Drer\LOC100148590, Drer\si:ch211-156l18.6, Drer\si:dkey-23f9.9, Drer\si:dkey-27d5.4, Drer\zgc:174355, Drer\zgc:174358, Drer\LOC100329825, Drer\zgc:174353" Scer\MPE1 Cele\rbpl-1 "Xtro\aff4, Xtro\rbbp6" "Mmus\Aff4, Mmus\Rbbp6" "Hsap\AFF4, Hsap\RBBP6" FBgn0267667 lncRNA:CR46005 - http://flybase.org/reports/FBgn0267667 non_protein_coding_gene - - - CR46005 - CR46005 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0016720 Reg-6 Rhythmically expressed gene 6 http://flybase.org/reports/FBgn0016720 - gene - - - "Dreg-6, Reg-6" - - 27-Aug-18 DroID_v2018_08 - - - - - - adult stage FBgn0022225 l(2)k03201 lethal (2) k03201 http://flybase.org/reports/FBgn0022225 - gene - - - l(2)k03201 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" crystal cell FBgn0031469 CG18558 - http://flybase.org/reports/FBgn0031469 protein_coding_gene glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity ; GO:0016263 | inferred from biological aspect of ancestor with PANTHER:PTN000547277 "O-glycan processing, core 1 ; GO:0016267 | inferred from biological aspect of ancestor with PANTHER:PTN000547277" membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR003378 "CG18558, dC1GalT3" IPR003378:Fringe-like CG18558 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-202e17.1, Drer\c1galt1b, Drer\LOC564281, Drer\c1galt1a, Drer\c1galt1c1" - "Cele\W09D10.5, Cele\C17A2.3, Cele\C16D9.6, Cele\E03H4.3, Cele\C02H6.1, Cele\Y38C1AB.1, Cele\F56H6.1, Cele\Y38C1AB.5, Cele\C38H2.2, Cele\T09E11.12, Cele\bus-4, Cele\F37A4.3" "Xtro\LOC100496837, Xtro\c1galt1" "Mmus\C1galt1, Mmus\C1galt1c1" "Hsap\C1GALT1C1, Hsap\C1GALT1" viable FBgn0040694 CG14974 - http://flybase.org/reports/FBgn0040694 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14974 - CG14974 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264893 lncRNA:CR44084 - http://flybase.org/reports/FBgn0264893 non_protein_coding_gene - - - CR44084 - CR44084 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000080 an ancon http://flybase.org/reports/FBgn0000080 - gene - - - an - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive" "leg,wing,macrochaeta & abdomen,eye,tergite" FBgn0028599 l(2)W9 lethal (2) W9 http://flybase.org/reports/FBgn0028599 gene - - - "l(2R)W9, l(2)W9" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0005432 fliK flightless K http://flybase.org/reports/FBgn0005432 "FBgn0000673, FBgn0001865" gene - - - "EM15, l(1)9Fc, fliK" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,heat sensitive,cell lethal,germline clone,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,flightless" FBgn0052027 lncRNA:CR32027 - http://flybase.org/reports/FBgn0052027 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE02231, CG32027, CR32027" - CR32027 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0050382 CG30382 - http://flybase.org/reports/FBgn0050382 protein_coding_gene "threonine-type endopeptidase activity ; GO:0004298 | inferred from electronic annotation with InterPro:IPR001353, InterPro:IPR023332 molecular_function ; GO:0003674 | no biological data available" cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from sequence or structural similarity with SGD:S000002979 positive regulation of dendrite morphogenesis ; GO:0050775 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype "proteasome core complex, alpha-subunit complex ; GO:0019773 | inferred from sequence or structural similarity with SGD:S000002979" "CG30382, 30382, Prosalpha1R, Prosalpha6, Pros-alpha1" "IPR001353:Proteasome, subunit alpha/beta, IPR000426:Proteasome alpha-subunit, N-terminal domain, IPR023332:Proteasome alpha-type subunit, IPR034642:Proteasome subunit alpha6, IPR029055:Nucleophile aminohydrolases, N-terminal" CG30382 27-Aug-18 DroID_v2018_08 "Drer\psma6l, Drer\psma6b, Drer\psma6a" Scer\SCL1 Cele\pas-1 Xtro\psma6 Mmus\Psma6 Hsap\PSMA6 DRSC29087 IEK -2.335959773 -2.87074977 -1.812772388 -1.150262632 2.154068764 1.458062574 FBgn0037672 sage salivary gland-expressed bHLH http://flybase.org/reports/FBgn0037672 protein_coding_gene "protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 RNA polymerase II core promoter proximal region sequence-specific DNA binding ; GO:0000978 | inferred from biological aspect of ancestor with PANTHER:PTN000468430 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with tap transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from biological aspect of ancestor with PANTHER:PTN000468430" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from sequence or structural similarity with tap positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay salivary gland development ; GO:0007431 | inferred from mutant phenotype" polytene chromosome ; GO:0005700 | inferred from direct assay nucleus ; GO:0005634 | inferred by curator from GO:0003700 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000468430 "Sage, CG12952, sage, bHLHc7" "IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG12952 27-Aug-18 DroID_v2018_08 "Drer\myf6, Drer\mespab, Drer\mespba, Drer\mespbb, Drer\mespaa, Drer\msgn1" - Cele\hlh-32 "Xtro\msgn1, Xtro\mespb, Xtro\mespa" "Mmus\Lyl1, Mmus\Msgn1, Mmus\Mesp2, Mmus\Mesp1" "Hsap\MESP2, Hsap\MESP1, Hsap\MSGN1" embryonic stage | stage >=10 adult salivary gland primordium

increased cell death embryonic/larval salivary gland FBgn0069335 UY3164 UY3164 http://flybase.org/reports/FBgn0069335 gene - - - UY3164 - - 27-Aug-18 DroID_v2018_08 - - - - - - neuroanatomy defective "mushroom body & axon7B,Kenyon cell,mushroom body & axoney-OK107" FBgn0051424 Ir94b Ionotropic receptor 94b http://flybase.org/reports/FBgn0051424 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "Ir94b, DmelIR94b, CG31424, IR94b" - CG31424 27-Aug-18 DroID_v2018_08 - - - - - - "body color defective,partially lethal - majority die,some die during pupal stage,auditory perception defective" mesothoracic tergum FBgn0002690 miniature-blistered miniature blistered http://flybase.org/reports/FBgn0002690 - gene - - - "mbs, miniature-blistered" - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,viable,poor,fertile" "wing,macrochaeta" FBgn0260860 Bet5 Blocked early in transport 5 http://flybase.org/reports/FBgn0260860 protein_coding_gene Rab guanyl-nucleotide exchange factor activity ; GO:0017112 | inferred from biological aspect of ancestor with PANTHER:PTN000583159 Rab guanyl-nucleotide exchange factor activity ; GO:0017112 | contributes_to inferred from sequence or structural similarity with SGD:S000004542 ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from sequence or structural similarity with SGD:S000004542 vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from biological aspect of ancestor with PANTHER:PTN000583159 TRAPP complex ; GO:0030008 | inferred from sequence or structural similarity TRAPP complex ; GO:0030008 | inferred from biological aspect of ancestor with PANTHER:PTN000583159 TRAPP complex ; GO:0030008 | inferred from sequence or structural similarity with SGD:S000004542 "CG1359, BET5, Bet5p, Bet5" "IPR007233:Trafficking protein particle complex subunit, IPR011012:Longin-like domain" CG1359 27-Aug-18 DroID_v2018_08 Drer\trappc1 "Scer\TRS23, Scer\BET5" "Cele\trpp-4, Cele\trpp-1, Cele\lec-12" Xtro\trappc1 Mmus\Trappc1 "Hsap\OSTC, Hsap\TRAPPC1" DRSC14600 IK 1.571367212 0.524431408 1.288070269 0.323657125 0.518423784 2.670901421 FBgn0066070 Su(var)2-6 Su(var)2-6 http://flybase.org/reports/FBgn0066070 gene - - - Su(var)2-6 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0045960 Stalker\sORF Stalker element sORF http://flybase.org/reports/FBgn0045960 transposable_element_gene - - - Stalker\sORF - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265176 lncRNA:CR44241 - http://flybase.org/reports/FBgn0265176 non_protein_coding_gene - - - "CR44241, CG34187" - CR44241 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0020563 anon-VI-C4 anon-VI-C4 http://flybase.org/reports/FBgn0020563 - gene - - - anon-VI-C4 - - 27-Aug-18 DroID_v2018_08 - - - - - - "Bolwig organ,Bolwig nerve" FBgn0259836 CR42405 Su(Ste):CR42405 http://flybase.org/reports/FBgn0259836 non_protein_coding_gene - - - "Su(Ste):CR42405, CR42405" - CR42405 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0012043 Bom Bombyxin http://flybase.org/reports/FBgn0012043 - gene - - - Bom - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0022165 l(2)k05614 lethal (2) k05614 http://flybase.org/reports/FBgn0022165 - gene - - - l(2)k05614 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0053380 5SrRNA:CR33380 5SrRNA:CR33380 http://flybase.org/reports/FBgn0053380 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33380, 5SrRNA:CR33380" - CR33380 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0061070 l(3)S018611b lethal (3) S018611b http://flybase.org/reports/FBgn0061070 gene - - - "0186/11, l(3)S018611b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0262989 lncRNA:CR43297 - http://flybase.org/reports/FBgn0262989 non_protein_coding_gene - - - "CR43297, lincRNA.967" - CR43297 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000246 c(3)G crossover suppressor on 3 of Gowen http://flybase.org/reports/FBgn0000246 "FBgn0038362, FBgn0063641" protein_coding_gene - synaptonemal complex assembly ; GO:0007130 | inferred from mutant phenotype reciprocal meiotic recombination ; GO:0007131 | inferred from mutant phenotype reciprocal meiotic recombination ; GO:0007131 | traceable author statement synaptonemal complex ; GO:0000795 | inferred from direct assay synaptonemal complex ; GO:0000795 | "C(3)G, CG17604, c(3)g, c3G, cx, c(3)G, C3G" - CG17604 27-Aug-18 DroID_v2018_08 - Scer\KAR5 - - - "Hsap\PPFIA3, Hsap\CCDC73" adult stage && O | stage S1-7 presumptive oocyte && oocyte

"meiotic cell cycle defective,female,wild-type,recessive,viable" "synaptonemal complex,synaptonemal complexnos.UTR.THsimVP16, c(3)G68,synaptonemal complexG68)nos.UTR.THsimVP16,oocyte & meiosis & nuclear chromosome,nurse cell & nuclear chromosome,germarium & nuclear chromosome,synaptonemal complexnos.UTR.THsimVP16, c(3)GCdel.UAS.PT.TZzzzFLAG,synaptonemal complexGCdel.UAS.PT.TZzzzFLAG)nos.UTR.THsimVP16,polytene chromosome chromocenter,meiotic cell cycle,meiotic metaphase I,meiotic anaphase I" FBgn0058064 ARY Aldehyde reductase Y http://flybase.org/reports/FBgn0058064 protein_coding_gene "oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR018170, InterPro:IPR020471" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR018170, InterPro:IPR020471" - "ARY, CG40064" "IPR018170:Aldo/keto reductase, conserved site, IPR020471:Aldo/keto reductase, IPR023210:NADP-dependent oxidoreductase domain" CG40064 27-Aug-18 DroID_v2018_08 "Drer\akr1b1, Drer\akr1a1b, Drer\zgc:56622, Drer\zgc:110782, Drer\akr1a1a, Drer\zgc:101765, Drer\si:dkey-180p18.9, Drer\zgc:110366" "Scer\ARA1, Scer\GRE3, Scer\YDL124W, Scer\GCY1, Scer\YJR096W, Scer\YPR1" "Cele\T08H10.1, Cele\C07D8.6, Cele\C56G3.2, Cele\Y39G8B.2, Cele\F53F1.2, Cele\ZC443.1, Cele\F53F1.3, Cele\K07C5.2, Cele\Y39G8B.1, Cele\C01G5.5" "Xtro\akr1d1, Xtro\LOC548351, Xtro\akr1c8p, Xtro\akr1c2, Xtro\akr1b1, Xtro\akr1a1, Xtro\akr1c1" "Mmus\Akr1c21, Mmus\Akr1b7, Mmus\Akr1c18, Mmus\Akr1a1, Mmus\Akr1c12, Mmus\Akr1d1, Mmus\Akr1cl, Mmus\Akr1c20, Mmus\Akr1b8, Mmus\Akr1b3, Mmus\Akr1e1, Mmus\Akr1b10, Mmus\Akr1c19, Mmus\Akr1c6, Mmus\Akr1c14, Mmus\Akr1c13" "Hsap\AKR1A1, Hsap\AKR1D1, Hsap\AKR1B10, Hsap\AKR1B15, Hsap\AKR1B1, Hsap\AKR1C4, Hsap\AKR1C3, Hsap\AKR1C1, Hsap\AKR1E2, Hsap\AKR1C2" FBgn0005351 streakex streakex http://flybase.org/reports/FBgn0005351 - gene - - - "streakex, stx" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,body color defective" thorax FBgn0263542 mir-4954 mir-4954 stem loop http://flybase.org/reports/FBgn0263542 miRNA_gene - - - "mir-4954, dme-mir-4954, CR43527" - CR43527 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262647 Nup160 Nucleoporin 160kD http://flybase.org/reports/FBgn0262647 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VCH5 nucleocytoplasmic transporter activity ; GO:0005487 | inferred from sequence or structural similarity with HGNC:18017 nucleocytoplasmic transporter activity ; GO:0005487 | inferred from biological aspect of ancestor with PANTHER:PTN000479965 mRNA export from nucleus ; GO:0006406 | inferred from sequence or structural similarity with HGNC:18017 double-strand break repair via homologous recombination ; GO:0000724 | inferred from mutant phenotype SMAD protein import into nucleus ; GO:0007184 | inferred from mutant phenotype nuclear pore ; GO:0005643 | inferred from biological aspect of ancestor with PANTHER:PTN000479965 nuclear pore ; GO:0005643 | inferred from direct assay nuclear pore outer ring ; GO:0031080 | inferred from sequence or structural similarity with HGNC:18017 "Nup160, CG4738, l(2)SH2055, l(2)SH2 2055, Nup160[mel], nup160, Nup" - CG4738 27-Aug-18 DroID_v2018_08 "Drer\nup160, Drer\LOC100535505" Scer\NUP120 Cele\npp-6 - Mmus\Nup160 Hsap\NUP160 DRSC02774 E -1.482368884 -0.124106381 -3.120267687 -1.625863346 -0.336750099 -0.341110484 FBgn0036730 qjt quijote http://flybase.org/reports/FBgn0036730 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR004181 SUMO transferase activity ; GO:0019789 | contributes_to inferred from sequence or structural similarity with SGD:S000000745 double-strand break repair via homologous recombination ; GO:0000724 | inferred from mutant phenotype DNA repair ; GO:0006281 | inferred from sequence or structural similarity with SGD:S000000745 Smc5-Smc6 complex ; GO:0030915 | inferred from sequence or structural similarity with SGD:S000000745 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000000745 "qjt, Quijote, CG13732, Nse2, Qjt" "IPR004181:Zinc finger, MIZ-type, IPR026846:E3 SUMO-protein ligase Nse2 (Mms21)" CG13732 27-Aug-18 DroID_v2018_08 Drer\nsmce2 Scer\MMS21 Cele\ZK1248.11 - Mmus\Nsmce2 Hsap\NSMCE2 FBgn0259259 C719.2 - http://flybase.org/reports/FBgn0259259 gene - - - C719.2 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing hair,wing,wing vein" FBgn0261813 lncRNA:CR42755 - http://flybase.org/reports/FBgn0261813 non_protein_coding_gene - - - "CG42755, CR42755" - CR42755 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265469 CG44362 - http://flybase.org/reports/FBgn0265469 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44362 - CG44362 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260468 CG7950 - http://flybase.org/reports/FBgn0260468 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG7950, Dromel_CG7950_FBtr0085563_CHCHD4inmorf_mORF" IPR010625:CHCH CG7950 27-Aug-18 DroID_v2018_08 "Drer\chchd4b, Drer\chchd4a" Scer\MIA40 "Cele\ZK616.3, Cele\F42H10.2, Cele\F11C1.1, Cele\ZK616.2" Xtro\chchd4 Mmus\Chchd4 Hsap\CHCHD4 DRSC28664 IK 2.175635786 0.510433806 0.616536938 -0.532649585 2.144138521 0.143507261 FBgn0010854 l(3)05057 lethal (3) 05057 http://flybase.org/reports/FBgn0010854 - gene - - - l(3)05057 - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0065494 l(2)SH1225 lethal (2) SH1225 http://flybase.org/reports/FBgn0065494 gene - - - "l(2)SH1225, l(2)SH2 1225" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0069117 mus213 mutagen-sensitive 213 http://flybase.org/reports/FBgn0069117 gene - - - mus213 - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,chemical sensitive" FBgn0066073 Su(var)2-13 Su(var)2-13 http://flybase.org/reports/FBgn0066073 gene - - - Su(var)2-13 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264355 4A1 - http://flybase.org/reports/FBgn0264355 gene - - - 4A1 - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,somatic clone" "eye,somatic clone" FBgn0002530 Lap-D Leucine aminopeptidase D http://flybase.org/reports/FBgn0002530 "FBgn0013289, FBgn0013290" gene aminopeptidase activity ; GO:0004177 | inferred from direct assay - cytosol ; GO:0005829 | inferred from direct assay "LAP, Lap, LAP-D, LapD, Lap-D" - - 27-Aug-18 DroID_v2018_08 - - - - - - electrophoretic variant FBgn0036771 CG14353 - http://flybase.org/reports/FBgn0036771 protein_coding_gene protein domain specific binding ; GO:0019904 | inferred from sequence or structural similarity with HGNC:9317 calcineurin-NFAT signaling cascade ; GO:0033173 | inferred from sequence or structural similarity with HGNC:9317 positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from sequence or structural similarity with HGNC:9317 calcineurin complex ; GO:0005955 | inferred from sequence or structural similarity with HGNC:9317 CG14353 "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR019775:WD40 repeat, conserved site" CG14353 27-Aug-18 DroID_v2018_08 "Drer\ppp3r1b, Drer\wdr92" - "Cele\cnb-1, Cele\Y54H5A.1" "Xtro\ppp3r1, Xtro\wdr92" "Mmus\Ppp3r1, Mmus\Ppp3r2, Mmus\Wdr92" "Hsap\PPP3R1, Hsap\WDR92, Hsap\PPP3R2" viable FBgn0026787 Nhe1 Na[+]/H[+] hydrogen exchanger 1 http://flybase.org/reports/FBgn0026787 - protein_coding_gene potassium:proton antiporter activity ; GO:0015386 | inferred from biological aspect of ancestor with PANTHER:PTN000011605 sodium:proton antiporter activity ; GO:0015385 | inferred from biological aspect of ancestor with PANTHER:PTN000011605 "sodium ion transport ; GO:0006814 | inferred from electronic annotation with InterPro:IPR004709, InterPro:IPR018409 regulation of intracellular pH ; GO:0051453 | inferred from biological aspect of ancestor with PANTHER:PTN000011605 potassium ion transmembrane transport ; GO:0071805 | inferred from biological aspect of ancestor with PANTHER:PTN000011605" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR004709, InterPro:IPR006153, InterPro:IPR018409, InterPro:IPR018422 Golgi apparatus ; GO:0005794 | inferred from biological aspect of ancestor with PANTHER:PTN000011723" "DmNHE1, NHE1, CG12178, Nhe1, nhe1" "IPR018409:Na+/H+ exchanger, isoform 8, IPR018422:Cation/H+ exchanger, CPA1 family, IPR004709:Na+/H+ exchanger, IPR006153:Cation/H+ exchanger" CG12178 27-Aug-18 DroID_v2018_08 "Drer\slc9a6a, Drer\slc9a8, Drer\slc9a6b" Scer\NHX1 Cele\nhx-8 "Xtro\slc9a9, Xtro\slc9a7, Xtro\slc9a6, Xtro\slc9a8" "Mmus\Slc9a6, Mmus\Slc9c1, Mmus\Slc9a9, Mmus\Slc9a7, Mmus\Slc9a8" "Hsap\SLC9A6, Hsap\SLC9A9, Hsap\SLC9C1, Hsap\SLC9A8, Hsap\SLC9A7" viable FBgn0010373 sib sibless http://flybase.org/reports/FBgn0010373 - gene - - - sib - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259718 CG42372 - http://flybase.org/reports/FBgn0259718 protein_coding_gene - - - "CG42372, Dromel_CG30100_FBtr0087140_uORF" IPR008011:Complex 1 LYR protein CG42372 27-Aug-18 DroID_v2018_08 Drer\sdhaf1 Scer\SDH6 - - Mmus\Sdhaf1 Hsap\SDHAF1 FBgn0010936 l(3)09656 lethal (3) 09656 http://flybase.org/reports/FBgn0010936 - gene - - - l(3)09656 - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,lethal,recessive" FBgn0061135 l(3)S001620b lethal (3) S001620b http://flybase.org/reports/FBgn0061135 gene - - - "0016/20, l(3)S001620b" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0065460 l(2)SH1380 lethal (2) SH1380 http://flybase.org/reports/FBgn0065460 gene - - - "l(2)SH1380, l(2)SH2 1380" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0267381 T:CycB.1-266 CycB degron sequence http://flybase.org/reports/FBgn0267381 engineered_tag - - - T:CycB.1-266 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060909 l(3)S043005a lethal (3) S043005a http://flybase.org/reports/FBgn0060909 gene - - - "0430/05, l(3)S043005a" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0243486 rdo reduced ocelli http://flybase.org/reports/FBgn0243486 protein_coding_gene - ocellus development ; GO:0008056 | inferred from mutant phenotype - "rdo, PFE, CG15151, CT35050, Rdo" "IPR003591:Leucine-rich repeat, typical subtype, IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like" CG15151 27-Aug-18 DroID_v2018_08 "Drer\ppp1r42, Drer\si:dkey-182i3.11" Scer\CYR1 Cele\dma-1 - Mmus\Ppp1r42 Hsap\PPP1R42 FBgn0060403 l(3)S131103 lethal (3) S131103 http://flybase.org/reports/FBgn0060403 gene - - - "1311/03, l(3)S131103" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0259952 Sfp24Bb Seminal fluid protein 24Bb http://flybase.org/reports/FBgn0259952 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "Sfp24Bb, CG42462, SFP24BB" IPR002223:Pancreatic trypsin inhibitor Kunitz domain CG42462 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002434 l(3)KX209 lethal (3) KX209 http://flybase.org/reports/FBgn0002434 - gene - - - l(3)KX209 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal peripheral nervous system FBgn0016801 l(1)K3 lethal (1) K3 http://flybase.org/reports/FBgn0016801 - gene - - - "l(1)K3, K3" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0061508 l(2)24Ab lethal (2) 24Ab http://flybase.org/reports/FBgn0061508 gene - - - l(2)24Ab - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0004158 l(2)51Ea lethal (2) 51Ea http://flybase.org/reports/FBgn0004158 - gene - - - l(2)51Ea - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage,female sterile,lethal,polyphasic,heat sensitive,lethal - all die before end of larval stage,some die during larval stage" FBgn0011224 heph hephaestus http://flybase.org/reports/FBgn0011224 "FBgn0010798, FBgn0011433, FBgn0029138, FBgn0039884, FBgn0039885, FBgn0051000" protein_coding_gene "translation repressor activity, nucleic acid binding ; GO:0000900 | inferred from mutant phenotype mRNA binding ; GO:0003729 | inferred from sequence or structural similarity mRNA 3'-UTR binding ; GO:0003730 | inferred from direct assay" mRNA processing ; GO:0006397 | inferred from electronic annotation with InterPro:IPR006536 spermatid development ; GO:0007286 | inferred from mutant phenotype imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype regulation of response to DNA damage stimulus ; GO:2001020 | inferred from genetic interaction with lok imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype negative regulation of oskar mRNA translation ; GO:0007319 | inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype sperm individualization ; GO:0007291 | inferred from mutant phenotype oocyte microtubule cytoskeleton polarization ; GO:0008103 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay intracellular ribonucleoprotein complex ; GO:0030529 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG31000, CG2290, dmPTB, PTB, Ptb, CG2094, ema, ptb, l(3)03429, l(3)j11B9, heph, HEPH, Heph, dPTB, hnRNP I, DmPTB" "IPR000504:RNA recognition motif domain, IPR006536:HnRNP-L/PTB, IPR015943:WD40/YVTN repeat-like-containing domain" CG31000 27-Aug-18 DroID_v2018_08 "Drer\ptbp3, Drer\ptbp1a, Drer\ptbp2a, Drer\ptbp2b, Drer\ptbp1b" Scer\MRD1 Cele\ptb-1 "Xtro\ptbp2, Xtro\ptbp1, Xtro\ptbp3" "Mmus\Ptbp3, Mmus\Ptbp2, Mmus\Ptbp1" "Hsap\PTBP1, Hsap\PTBP3, Hsap\PTBP2" "viable,fertile,learning defective,lethal,male sterile,recessive,heat sensitive,visible,somatic clone,mitotic cell cycle defective,female fertile" "wing,testis,spermatozoon,individualization stage spermatid,spermatid cyst,elongation stage spermatid,germline cell,male,macrochaeta,wing vein,cell autonomous,somatic clone,wing margin,ectopic,embryonic head,germline clone,trichogen cell,mesothoracic tergum" DRSC14085 IE -0.910237949 -1.539103529 -0.008490841 -1.831969216 -0.369370127 0.374456334 FBgn0263333 lncRNA:CR43414 - http://flybase.org/reports/FBgn0263333 non_protein_coding_gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype - "CR43414, lincRNA.205" - CR43414 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051352 Unc-115a Uncoordinated 115a http://flybase.org/reports/FBgn0051352 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781 actin binding ; GO:0003779 | inferred from sequence or structural similarity with HGNC:12690 cytoskeleton organization ; GO:0007010 | inferred from electronic annotation with InterPro:IPR003128 photoreceptor cell axon guidance ; GO:0072499 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype - "CG9489, anon-WO0140519.21, unc-115, CG31352, dunc-115, Unc-115a, Dunc-115" "IPR001781:Zinc finger, LIM-type, IPR003128:Villin headpiece" CG31352 27-Aug-18 DroID_v2018_08 "Drer\ablim1b, Drer\ablim3, Drer\ablim1a, Drer\dmtn, Drer\ablim2" - Cele\unc-115 "Xtro\dmtn, Xtro\ablim3, Xtro\ablim2" "Mmus\Ablim3, Mmus\Dmtn, Mmus\Ablim1, Mmus\Ablim2" "Hsap\DMTN, Hsap\ABLIM2, Hsap\ABLIM1, Hsap\ABLIM3" "viable,visible,fertile,neuroanatomy defective" "mesothoracic tergum,lamina plexus,eye photoreceptor cell,segmental nerve,embryonic ventral neuromere,longitudinal connective" FBgn0040609 CG3348 - http://flybase.org/reports/FBgn0040609 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG3348 IPR002557:Chitin binding domain CG3348 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC15480 I 1.570023063 -0.125233726 -1.274720235 0.185065206 0.245618456 -0.329843495 FBgn0267476 lncRNA:CR45826 - http://flybase.org/reports/FBgn0267476 non_protein_coding_gene - - - CR45826 - CR45826 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0053158 CG33158 - http://flybase.org/reports/FBgn0053158 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR000795, InterPro:IPR004161, InterPro:IPR005225 GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR000795" - cytosol ; GO:0005829 | inferred from direct assay "CG10162, CG4638, CG33158" "IPR000640:Translation elongation factor EFG, V domain, IPR000795:Transcription factor, GTP-binding domain, IPR004161:Translation elongation factor EFTu-like, domain 2, IPR005225:Small GTP-binding protein domain, IPR009000:Translation protein, beta-barrel domain, IPR009022:Elongation factor G, III-V domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR014721:Ribosomal protein S5 domain 2-type fold, subgroup, IPR020568:Ribosomal protein S5 domain 2-type fold" CG33158 27-Aug-18 DroID_v2018_08 Drer\eftud1 Scer\RIA1 Cele\K10C3.5 Xtro\efl1 Mmus\Efl1 Hsap\EFL1 "viable,fertile,song defective" FBgn0041174 Vhl von Hippel-Lindau http://flybase.org/reports/FBgn0041174 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q7KRW1 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q15369 "protein ubiquitination ; GO:0016567 | inferred from direct assay open tracheal system development ; GO:0007424 | inferred from mutant phenotype protein export from nucleus ; GO:0006611 | inferred from mutant phenotype negative regulation of microtubule depolymerization ; GO:0007026 | inferred from mutant phenotype epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype trachea development ; GO:0060438 | inferred from mutant phenotype establishment or maintenance of polarity of follicular epithelium ; GO:0016334 | inferred from mutant phenotype lumen formation, open tracheal system ; GO:0035149 | inferred from mutant phenotype centrosome organization ; GO:0051297 | inferred from genetic interaction with mgr mitotic spindle assembly ; GO:0090307 | inferred from genetic interaction with mgr regulation of cellular response to hypoxia ; GO:1900037 | inferred from mutant phenotype" VCB complex ; GO:0030891 | inferred from direct assay "dVHL, VHL, d-VHL, dmVHL, d-vhl, vhl, CG13221, BcDNA:RH61560, Vhl, DVhl, Dvhl" "IPR024053:von Hippel-Lindau disease tumour suppressor, beta domain, IPR002714:Von Hippel-Lindau tumour suppressor protein, IPR022772:von Hippel-Lindau disease tumour suppressor, beta/alpha domain" CG13221 27-Aug-18 DroID_v2018_08 "Drer\vhl, Drer\vhll" - Cele\vhl-1 Xtro\vhl Mmus\Vhl "Hsap\VHL, Hsap\VHLL" "cell migration defective,lethal,viable,stress response defective,partially lethal - majority die,visible,planar polarity defective,cell polarity defective,somatic clone,recessive,non-rescuable maternal effect,lethal - all die before end of first instar larval stage,some die during first instar larval stage,female sterile" "border follicle cell | oogenesis stage S10,border follicle cell | oogenesis stage S9,embryonic/larval trachea,embryonic/larval dorsal trunk,embryonic/larval dorsal branch,embryonic/larval lateral trunk,tracheal primordium,ectopic,tracheole,cell non-autonomous,presumptive embryonic/larval tracheal system,transverse connective primordium,visceral branch primordium,lateral trunk primordium,dorsal trunk primordium,trichogen cell,follicle cell,somatic clone,microtubule | somatic clone,embryonic/larval tracheal system,maternal effect,egg chamber,nurse cell,microtubulebtl.PS,heat sensitive" FBgn0265898 lncRNA:CR44687 - http://flybase.org/reports/FBgn0265898 non_protein_coding_gene - - - "CR44687, lincRNA.640, lincRNA.651" - CR44687 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0025612 CG3062 - http://flybase.org/reports/FBgn0025612 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available cilium organization ; GO:0044782 | inferred from biological aspect of ancestor with PANTHER:PTN002161271 ciliary basal body ; GO:0036064 | inferred from biological aspect of ancestor with PANTHER:PTN002161271 "EG:84H4.5, CG3062" - CG3062 27-Aug-18 DroID_v2018_08 Drer\cfap126 - - - Mmus\Cfap126 Hsap\CFAP126 viable FBgn0028491 CG2930 - http://flybase.org/reports/FBgn0028491 protein_coding_gene "transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR000109, InterPro:IPR018456" oligopeptide transport ; GO:0006857 | inferred from electronic annotation with InterPro:IPR018456 "membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR000109, InterPro:IPR018456" "BcDNA:GH06717, CG32787, CG32780, CG2930" "IPR000109:Proton-dependent oligopeptide transporter family, IPR020846:Major facilitator superfamily domain, IPR018456:PTR2 family proton/oligopeptide symporter, conserved site" CG2930 27-Aug-18 DroID_v2018_08 "Drer\slc15a1a, Drer\slc15a4, Drer\slc15a1b, Drer\slc15a2, Drer\si:ch211-190o6.3" Scer\PTR2 "Cele\pept-3, Cele\pept-1, Cele\pept-2" "Xtro\slc15a4, Xtro\slc15a2, Xtro\slc15a1" "Mmus\Slc15a3, Mmus\Slc15a5, Mmus\Slc15a4, Mmus\Slc15a1, Mmus\Slc15a2" "Hsap\SLC15A5, Hsap\SLC15A1, Hsap\SLC15A3, Hsap\SLC15A2, Hsap\SLC15A4" viable FBgn0005635 belt belt http://flybase.org/reports/FBgn0005635 - gene - - - belt - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005356 su(msm1) suppressor of msm1 http://flybase.org/reports/FBgn0005356 - gene - - - "su(m1[5A]), su(msm1)" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267666 lncRNA:CR46004 - http://flybase.org/reports/FBgn0267666 non_protein_coding_gene - - - CR46004 - CR46004 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060586 l(3)S093902 lethal (3) S093902 http://flybase.org/reports/FBgn0060586 gene - - - "0939/02, l(3)S093902" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0069918 CG41134 - http://flybase.org/reports/FBgn0069918 protein_coding_gene - - - CG41134 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065949 l(2)SH0086 lethal (2) SH0086 http://flybase.org/reports/FBgn0065949 gene - - - "l(2)SH0086, l(2)SH2 0086" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0016962 umpA uncoordinated with mechanoreceptor potential A http://flybase.org/reports/FBgn0016962 - gene - - - umpA - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0053369 5SrRNA:CR33369 5SrRNA:CR33369 http://flybase.org/reports/FBgn0053369 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33369, 5SrRNA:CR33369" - CR33369 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0026336 Su(tor)2-68-20 Su(tor)2-68-20 http://flybase.org/reports/FBgn0026336 - gene - - - Su(tor)2-68-20 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0064181 hh-CMM hh-CMM http://flybase.org/reports/FBgn0064181 regulatory_region - - - "hh CMM, hh-CMM" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262759 Mst77Y-10Psi Male-specific pseudogene 77Y 10 http://flybase.org/reports/FBgn0262759 pseudogene_attribute - - - Mst77Y-10Psi - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0016057 prd6 prd6 http://flybase.org/reports/FBgn0016057 - gene - - - prd6 - - 27-Aug-18 DroID_v2018_08 - - - - - - " oogenesis stage , embryonic stage | <8-12 hr " FBgn0026149 BCL7-like BCL7-like http://flybase.org/reports/FBgn0026149 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG17252, BCL7-like, Bcl7-like" IPR006804:BCL7 CG17252 27-Aug-18 DroID_v2018_08 "Drer\bcl7a, Drer\bcl7bb, Drer\bcl7ba" - Cele\bcl-7 "Xtro\bcl7c, Xtro\bcl7b, Xtro\bcl7a" "Mmus\Bcl7b, Mmus\Bcl7a, Mmus\Bcl7c" "Hsap\BCL7B, Hsap\BCL7C, Hsap\BCL7A" "viable,fertile,visible" mesothoracic tergum FBgn0285926 Imp IGF-II mRNA-binding protein http://flybase.org/reports/FBgn0285926 protein_coding_gene mRNA 3'-UTR binding ; GO:0003730 | inferred from direct assay "nervous system development ; GO:0007399 | inferred from mutant phenotype synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011|GO:0071013 spermatogenesis ; GO:0007283 | inferred from expression pattern neuron remodeling ; GO:0016322 | inferred from mutant phenotype positive regulation of axon regeneration ; GO:0048680 | inferred from mutant phenotype carbohydrate metabolic process ; GO:0005975 | inferred from mutant phenotype response to starvation ; GO:0042594 | inferred from mutant phenotype" precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay axon ; GO:0030424 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "imp, Imp, IMP, ORE-9, CG1691, dIMP, cg1691, l(1)G0072, anon-EST:fe2B3, IGF-II, anon-WO0140519.39, IMP-1, MRE11, mre11, IGF2BP1, FGC026A04" "IPR004087:K Homology domain, IPR004088:K Homology domain, type 1, IPR000504:RNA recognition motif domain" CG1691 27-Aug-18 DroID_v2018_08 "Drer\igf2bp1, Drer\igf2bp2a, Drer\igf2bp2b, Drer\igf2bp3" - "Cele\zbp-1, Cele\M01A10.1" Xtro\igf2bp3 "Mmus\Igf2bp2, Mmus\Igf2bp1, Mmus\Igf2bp3" "Hsap\IGF2BP1, Hsap\IGF2BP2, Hsap\IGF2BP3" FBgn0087015 l(3)61Dc lethal (3) 61Dc http://flybase.org/reports/FBgn0087015 gene - - - l(3)61Dc - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,lethal" FBgn0065097 snmRNA:357 small non-messenger RNA 357 http://flybase.org/reports/FBgn0065097 non_protein_coding_gene - - - "Dm-357, CR33659, snmRNA:357" - CR33659 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264992 lncRNA:CR44143 - http://flybase.org/reports/FBgn0264992 non_protein_coding_gene - - - CR44143 - CR44143 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0061361 CG33786 - http://flybase.org/reports/FBgn0061361 protein_coding_gene double-stranded RNA binding ; GO:0003725 | inferred from electronic annotation with InterPro:IPR006070 tRNA binding ; GO:0000049 | inferred from biological aspect of ancestor with PANTHER:PTN000426057 nucleotidyltransferase activity ; GO:0016779 | inferred from biological aspect of ancestor with PANTHER:PTN000426057 tRNA threonylcarbamoyladenosine modification ; GO:0002949 | inferred from biological aspect of ancestor with PANTHER:PTN000426057 regulation of translational fidelity ; GO:0006450 | inferred from biological aspect of ancestor with PANTHER:PTN000426057 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000426057 "CG33005, CG10438b, CG10438, CG33005-ORFB, CG33786, Dromel_CG33786_FBtr0091786_mORF, CG33005ORFB, sua5" "IPR006070:YrdC-like domain, IPR017945:DHBP synthase RibB-like alpha/beta domain" CG33786 27-Aug-18 DroID_v2018_08 "Drer\yrdc, Drer\si:ch211-153b23.4, Drer\polr3k" "Scer\SUA5, Scer\RPC11" "Cele\rpc-11, Cele\Y48C3A.18" "Xtro\polr3k, Xtro\yrdc" "Mmus\Yrdc, Mmus\Polr3k" "Hsap\POLR3K, Hsap\YRDC" FBgn0034304 CG5742 - http://flybase.org/reports/FBgn0034304 protein_coding_gene receptor binding ; GO:0005102 | inferred from biological aspect of ancestor with PANTHER:PTN000966452 neurogenesis ; GO:0022008 | inferred from mutant phenotype regulation of receptor biosynthetic process ; GO:0010869 | inferred from biological aspect of ancestor with PANTHER:PTN000966452 protein retention in ER lumen ; GO:0006621 | inferred from biological aspect of ancestor with PANTHER:PTN000966452 endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000966452 CG5742 "IPR002110:Ankyrin repeat, IPR020683:Ankyrin repeat-containing domain, IPR021832:Ankyrin repeat domain-containing protein 13" CG5742 27-Aug-18 DroID_v2018_08 "Drer\ankrd13c, Drer\ankrd13d, Drer\ankrd13b, Drer\ankrd13a" - Cele\C01F1.6 "Xtro\ankrd13c, Xtro\ankrd13b, Xtro\ankrd13a" "Mmus\Ankrd13c, Mmus\Ankrd13b, Mmus\Ankrd13a, Mmus\Ankrd13d" "Hsap\ANKRD13B, Hsap\ANKRD13A, Hsap\ANKRD13C, Hsap\ANKRD13D" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0011222 gru gruyere http://flybase.org/reports/FBgn0011222 - gene - spermatid development ; GO:0007286 | inferred from mutant phenotype - gru - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,male sterile,partially lethal - majority die" Nebenkern FBgn0064187 ctu count-up http://flybase.org/reports/FBgn0064187 gene - - - ctu - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0019651 su(mbm) suppressor of mushroom body miniature http://flybase.org/reports/FBgn0019651 - gene - - - su(mbm) - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0025620 CG13360 - http://flybase.org/reports/FBgn0025620 - protein_coding_gene - - - "EG:34F3.5, CG13360" "IPR015897:CHK kinase-like, IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain" CG13360 27-Aug-18 DroID_v2018_08 - - "Cele\C29F7.2, Cele\T16G1.3, Cele\nhr-246, Cele\C29F7.1, Cele\dhs-27, Cele\H06H21.8" - - - viable FBgn0267053 CR45497 - http://flybase.org/reports/FBgn0267053 pseudogene_attribute - - - CR45497 - CR45497 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034552 CG17999 - http://flybase.org/reports/FBgn0034552 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR000873 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR000873 - CG17999 "IPR020845:AMP-binding, conserved site, IPR025110:AMP-binding enzyme C-terminal domain, IPR000873:AMP-dependent synthetase/ligase" CG17999 27-Aug-18 DroID_v2018_08 "Drer\acsbg1, Drer\acsf3" Scer\PCS60 "Cele\acs-9, Cele\acs-7, Cele\acs-14, Cele\acs-6, Cele\C25G6.3, Cele\mec-18, Cele\acs-10, Cele\sur-5, Cele\C32E8.6" Xtro\acsf3 "Mmus\Aacs, Mmus\Acsf3, Mmus\Acsbg1" "Hsap\ACSF3, Hsap\ACSBG1, Hsap\AACS" viable FBgn0267688 lncRNA:CR46024 - http://flybase.org/reports/FBgn0267688 non_protein_coding_gene - - - CR46024 - CR46024 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0086704 stops slow termination of phototransduction http://flybase.org/reports/FBgn0086704 protein_coding_gene - intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR001496 deactivation of rhodopsin mediated signaling ; GO:0016059 | inferred from mutant phenotype sensory perception of sound ; GO:0007605 | inferred from mutant phenotype - "CG31006, CG15559, CG15558, CG15557, su(rdgB)69, stops" IPR001496:SOCS box domain CG31006 27-Aug-18 DroID_v2018_08 - - - - Mmus\Asb17 Hsap\ASB17 FBgn0046640 anon-38D.4 anon-38D.4 http://flybase.org/reports/FBgn0046640 gene - - - "38D.4, anon-38D.4" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031824 CG9547 - http://flybase.org/reports/FBgn0031824 protein_coding_gene flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR013786 glutaryl-CoA dehydrogenase activity ; GO:0004361 | inferred from sequence or structural similarity with UniProtKB:Q92947 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006091, InterPro:IPR009075, InterPro:IPR009100, InterPro:IPR013786 tryptophan metabolic process ; GO:0006568 | inferred from sequence or structural similarity with UniProtKB:Q92947 lysine catabolic process ; GO:0006554 | inferred from sequence or structural similarity with UniProtKB:Q92947 hydroxylysine catabolic process ; GO:0046948 | inferred from sequence or structural similarity with UniProtKB:Q92947" microtubule associated complex ; GO:0005875 | inferred from direct assay mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:Q92947 "152078_at, CG9547" "IPR006091:Acyl-CoA oxidase/dehydrogenase, central domain, IPR009075:Acyl-CoA dehydrogenase/oxidase C-terminal, IPR009100:Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain, IPR013786:Acyl-CoA dehydrogenase/oxidase, N-terminal" CG9547 27-Aug-18 DroID_v2018_08 "Drer\gcdha, Drer\gcdhb" - "Cele\F54D5.7, Cele\acdh-10" Xtro\gcdh Mmus\Gcdh Hsap\GCDH DRSC03260 K -0.49002739 -0.396702213 0.227175872 0.211034442 2.069404073 0.002644414 FBgn0014068 Su(tor)3-344 Su(tor)3-344 http://flybase.org/reports/FBgn0014068 - gene - - - Su(tor)3-344 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0014885 Su(phl)4 Suppressor of pole hole 4 http://flybase.org/reports/FBgn0014885 - gene - - - "Su(D-raf)4, Su(phl)4" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0026218 l(3)06265 lethal (3) 06265 http://flybase.org/reports/FBgn0026218 - gene - - - l(3)06265 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0029801 CG15771 - http://flybase.org/reports/FBgn0029801 protein_coding_gene "hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR006439, InterPro:IPR011950" metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR006439 - "CR33074, CG15771, 28571108" "IPR006439:HAD hydrolase, subfamily IA, IPR011950:HAD-superfamily hydrolase, subfamily IA, CTE7, IPR023214:HAD-like domain" CG15771 27-Aug-18 DroID_v2018_08 "Drer\hdhd3, Drer\nanp, Drer\ephx2" "Scer\YOR131C, Scer\YMR130W" "Cele\K01G5.10, Cele\F09C3.2, Cele\K09H11.1, Cele\C04E6.7" "Xtro\acad10, Xtro\ephx2, Xtro\hdhd3, Xtro\nanp" "Mmus\Nanp, Mmus\Hdhd3, Mmus\Ephx2, Mmus\Acad10" "Hsap\ACAD10, Hsap\EPHX2, Hsap\HDHD3, Hsap\NANP" viable embryonic/larval hemocyte | third instar larval stage FBgn0041153 freshair freshair http://flybase.org/reports/FBgn0041153 gene - - - freshair - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0082922 snoRNA:Or-aca4 snoRNA:Or-aca4 http://flybase.org/reports/FBgn0082922 snoRNA_gene - - - "snoRNA:Or-aca4, DmOr_aca4 snoRNA, DmOr_aca4, CR34543, Or-aca4, Oaca-4, chr2R:13131609..13131698, snoRNA:Or-ACA4" - CR34543 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030048 CG12112 - http://flybase.org/reports/FBgn0030048 protein_coding_gene - - - CG12112 IPR032071:Domain of unknown function DUF4806 CG12112 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" FBgn0014213 l(2)31Ba lethal (2) 31Ba http://flybase.org/reports/FBgn0014213 - gene - - - l(2)31Ba - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0085192 CG34163 - http://flybase.org/reports/FBgn0085192 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34163 - CG34163 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002282 l(3)73Ag lethal (3) 73Ag http://flybase.org/reports/FBgn0002282 - gene - - - "l(3)133.59, l(3)73Ag" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal "adult abdomen,tergite" FBgn0002288 l(3)73Ca lethal (3) 73Ca http://flybase.org/reports/FBgn0002288 - gene - - - l(3)73Ca - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0031596 CG15429 - http://flybase.org/reports/FBgn0031596 protein_coding_gene - lateral inhibition ; GO:0046331 | inferred from mutant phenotype - "BcDNA:AT23465, CG15429" IPR001199:Cytochrome b5-like heme/steroid binding domain CG15429 27-Aug-18 DroID_v2018_08 Drer\cyb5d1 - - Xtro\cyb5d1 Mmus\Cyb5d1 Hsap\CYB5D1 "viable,visible" chaeta FBgn0028564 slug slug http://flybase.org/reports/FBgn0028564 gene - - - slug - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" larva FBgn0019749 l(1)815-5 lethal (1) 815-5 http://flybase.org/reports/FBgn0019749 - gene - - - l(1)815-5 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0015356 anon-99Ce anon-99Ce http://flybase.org/reports/FBgn0015356 - gene - - - anon-99Ce - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0019908 air aircraft http://flybase.org/reports/FBgn0019908 - gene - - - air - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile,flightless" wing FBgn0069956 CG41063 - http://flybase.org/reports/FBgn0069956 protein_coding_gene - - - CG41063 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032299 CG17127 - http://flybase.org/reports/FBgn0032299 protein_coding_gene - - - CG17127 - CG17127 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034301 CG5756 - http://flybase.org/reports/FBgn0034301 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG5756 IPR002557:Chitin binding domain CG5756 27-Aug-18 DroID_v2018_08 - - Cele\Y56A3A.6 - - - "viable,visible" mesothoracic tergum FBgn0266914 lncRNA:CR45374 - http://flybase.org/reports/FBgn0266914 non_protein_coding_gene - - - CR45374 - CR45374 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0014331 l(3)ry87 lethal (3) ry87 http://flybase.org/reports/FBgn0014331 - gene - - - l(3)ry87 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0034272 Ir54a Ionotropic receptor 54a http://flybase.org/reports/FBgn0034272 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "Ir54a, DmelIR54a, CG14487, IR54a" - CG14487 27-Aug-18 DroID_v2018_08 "Drer\grik4, Drer\grik1a, Drer\grik1b, Drer\si:dkey-183j2.10, Drer\si:ch211-251b21.1" - "Cele\glr-4, Cele\glr-5" - "Mmus\Grik1, Mmus\Grik4" "Hsap\GRIK1, Hsap\GRIK4" viable DRSC06459 K 0.152835364 -0.162004685 0.301238081 0.461127447 1.500600904 0.769335715 FBgn0053367 5SrRNA:CR33367 5SrRNA:CR33367 http://flybase.org/reports/FBgn0053367 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33367, 5SrRNA:CR33367" - CR33367 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060754 l(3)S064316a lethal (3) S064316a http://flybase.org/reports/FBgn0060754 gene - - - "0643/16, l(3)S064316a" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0031279 CG3544 - http://flybase.org/reports/FBgn0031279 protein_coding_gene xylulokinase activity ; GO:0004856 | inferred from biological aspect of ancestor with PANTHER:PTN000023215 xylulokinase activity ; GO:0004856 | inferred from sequence or structural similarity with HGNC:12839 xylulose metabolic process ; GO:0005997 | inferred from biological aspect of ancestor with PANTHER:PTN000023215 xylulose metabolic process ; GO:0005997 | inferred from sequence or structural similarity with HGNC:12839 carbohydrate phosphorylation ; GO:0046835 | inferred from sequence or structural similarity with HGNC:12839 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000023213 extracellular exosome ; GO:0070062 | inferred from sequence or structural similarity with HGNC:12839 CG3544 "IPR018484:Carbohydrate kinase, FGGY, N-terminal, IPR018485:Carbohydrate kinase, FGGY, C-terminal" CG3544 27-Aug-18 DroID_v2018_08 Drer\xylb Scer\XKS1 Cele\R08D7.7 - Mmus\Xylb Hsap\XYLB viable FBgn0028030 l(3)S102702a lethal (3) S102702a http://flybase.org/reports/FBgn0028030 gene - - - "1027/02, l(3)S102702, l(3)S102702a" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0086472 RpS25 Ribosomal protein S25 http://flybase.org/reports/FBgn0086472 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from direct assay cytoplasmic translation ; GO:0002181 | traceable author statement cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 cytosolic ribosome ; GO:0022626 | inferred from direct assay cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement ribosome ; GO:0005840 | inferred from direct assay "RpS25, anon-EST:Posey260, RpS31, D25, CG6684, M(3)S32, M(3)s[32], M(3)S31, M(3)86D, S25, Rp S25, Rps25" "IPR004977:Ribosomal protein S25, IPR011991:Winged helix-turn-helix DNA-binding domain" CG6684 27-Aug-18 DroID_v2018_08 Drer\rps25 "Scer\RPS25A, Scer\RPS25B" Cele\rps-25 Xtro\rps25 Mmus\Rps25 Hsap\RPS25 DRSC16837 I 1.760477892 0.057942348 0.169615307 -0.055630064 -0.185561351 0.767995142 FBgn0028105 l(3)S071501 lethal (3) S071501 http://flybase.org/reports/FBgn0028105 gene - - - "0715/01, l(3)S071501" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0036936 CG14185 - http://flybase.org/reports/FBgn0036936 protein_coding_gene - - - "CT33794, CG14185" "IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like" CG14185 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-267j14.7, Drer\cep97, Drer\drc3, Drer\lrrc6, Drer\lrrcc1, Drer\si:ch211-103e16.5, Drer\lrrc9, Drer\lrrc23, Drer\lrrc61, Drer\ppp1r7, Drer\lrriq1, Drer\lrguk" "Scer\NUD1, Scer\SDS22" - "Xtro\cep97, Xtro\lrrc49, Xtro\lrrc23, Xtro\dnal1, Xtro\lrrc6, Xtro\drc3, Xtro\ppp1r7, Xtro\lrrc9, Xtro\lrrcc1, Xtro\lrrc56" "Mmus\Lrguk, Mmus\Ppp1r7, Mmus\Lrrc61, Mmus\Lrrc48, Mmus\Lrrc49, Mmus\Lrrc56, Mmus\Lrrc46, Mmus\Lrrc9, Mmus\Lrriq1, Mmus\Dnal1, Mmus\Lrrcc1, Mmus\Lrrc43, Mmus\Lrrc23, Mmus\Cep97, Mmus\Lrriq3, Mmus\Lrrc6" "Hsap\LRRCC1, Hsap\LRRIQ3, Hsap\PPP1R7, Hsap\LRRC43, Hsap\DNAL1, Hsap\LRRC56, Hsap\DRC3, Hsap\CEP97, Hsap\LRRC61, Hsap\LRRIQ1, Hsap\LRRC6, Hsap\LRRC46, Hsap\LRGUK, Hsap\LRRC49, Hsap\LRRC23" "viable,visible" mesothoracic tergum FBgn0014262 l(2)X lethal (2) X http://flybase.org/reports/FBgn0014262 - gene - - - l(2)X - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001252 im interrupted margin http://flybase.org/reports/FBgn0001252 - gene - - - im - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,female sterile,viable,male,reduced" "wing vein,costal vein,eye,macrochaeta,wing" FBgn0024229 hnc13 hnc13 http://flybase.org/reports/FBgn0024229 FBgn0026237 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "h-NC13, hnc13" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0027171 l(2)B2 lethal (2) B2 http://flybase.org/reports/FBgn0027171 - gene - - - l(2)B2 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0027185 l(2)60A-H lethal (2) 60A-H http://flybase.org/reports/FBgn0027185 - gene - - - l(2)60A-H - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0086659 snoRNA:Psi18S-176 snoRNA:Psi18S-176 http://flybase.org/reports/FBgn0086659 snoRNA_gene - - - "psi18s-176, snoRNA:314, Dm-314, CR33913, Psi 18S-176(SnoR314), snoRNA:Psi18S-176" - CR33913 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060741 l(3)S066610b lethal (3) S066610b http://flybase.org/reports/FBgn0060741 gene - - - "0666/10, l(3)S066610b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0266968 lncRNA:CR45419 - http://flybase.org/reports/FBgn0266968 non_protein_coding_gene - - - CR45419 - CR45419 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264373 lncRNA:CR43825 - http://flybase.org/reports/FBgn0264373 non_protein_coding_gene - - - CR43825 - CR43825 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060634 l(3)S085005b lethal (3) S085005b http://flybase.org/reports/FBgn0060634 gene - - - "0850/05, l(3)S085005b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0001900 l(2)22Aa lethal (2) 22Aa http://flybase.org/reports/FBgn0001900 - gene - - - "l(2)neh-14, l(2)neh14, l(2)22Aa" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0024433 Dl-l Delta-like http://flybase.org/reports/FBgn0024433 - gene molecular_function ; GO:0003674 | no biological data available gonadal mesoderm development ; GO:0007506 | inferred from mutant phenotype germ cell migration ; GO:0008354 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available Dl-l - - 27-Aug-18 DroID_v2018_08 - - - - - - embryo FBgn0053489 CG33489 - http://flybase.org/reports/FBgn0053489 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG6110, CG33489" - CG33489 27-Aug-18 DroID_v2018_08 Drer\efhb - - - Mmus\Efhb Hsap\EFHB "viable,fertile" FBgn0030025 CG2147 - http://flybase.org/reports/FBgn0030025 protein_coding_gene - - - "BcDNA:LP02728, CG2147" - CG2147 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030836 CG8664 - http://flybase.org/reports/FBgn0030836 protein_coding_gene - - - CG8664 - CG8664 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0014910 anon-4Fd anon-4Fd http://flybase.org/reports/FBgn0014910 - gene - - - anon-4Fd - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0027885 Aac11 Aac11 http://flybase.org/reports/FBgn0027885 FBgn0022116 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Acn negative regulation of apoptotic process ; GO:0043066 | inferred from sequence or structural similarity negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype inferred from genetic interaction with E2f1 inferred from genetic interaction with Rbf neurogenesis ; GO:0022008 | inferred from mutant phenotype negative regulation of apoptotic process ; GO:0043066 | inferred from sequence or structural similarity with HGNC:594 nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q9BZZ5 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:594 "l(2)k06710, BcDNA.LD09852, CG6582, BcDNA:LD09852, Aac11, Api5, AAC-11" "IPR008383:Apoptosis inhibitory 5, IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical" CG6582 27-Aug-18 DroID_v2018_08 Drer\api5 - - Xtro\api5 Mmus\Api5 Hsap\API5 "lethal,recessive,visible,neuroanatomy defective" "wing blade,embryonic/larval neuroblast,ganglion mother cell" FBgn0265219 shf::Hsap\WIF1 - http://flybase.org/reports/FBgn0265219 engineered_fusion_gene - - - shf::Hsap\WIF1 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034046 tun tungus http://flybase.org/reports/FBgn0034046 protein_coding_gene "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides ; GO:0016811 | inferred from electronic annotation with InterPro:IPR023128" olfactory learning ; GO:0008355 | inferred from mutant phenotype learning or memory ; GO:0007611 | inferred from mutant phenotype - "CG8253, BcDNA:LD38553, tun, Ntaq1" "IPR023128:Protein N-terminal glutamine amidohydrolase, alpha beta roll" CG8253 27-Aug-18 DroID_v2018_08 Drer\wdyhv1 - Cele\R06C7.6 Xtro\wdyhv1 Mmus\Wdyhv1 Hsap\WDYHV1 "viable,memory defective" FBgn0036273 INPP5E Inositol polyphosphate 5-phosphatase E http://flybase.org/reports/FBgn0036273 protein_coding_gene "phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity ; GO:0004439 | inferred from sequence or structural similarity with SGD:S000001264 inositol trisphosphate phosphatase activity ; GO:0046030 | non-traceable author statement" protein localization to cilium ; GO:0061512 | inferred from mutant phenotype phosphatidylinositol dephosphorylation ; GO:0046856 | inferred from sequence or structural similarity with SGD:S000001264 dephosphorylation ; GO:0016311 | non-traceable author statement sensory perception of sound ; GO:0007605 | inferred from mutant phenotype ciliary base ; GO:0097546 | inferred from direct assay membrane ; GO:0016020 | inferred from sequence or structural similarity with SGD:S000001264 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000001264 "IPP, CG10426, INPP5E, INPPE5, dInpp5e" "IPR000300:Inositol polyphosphate-related phosphatase, IPR005135:Endonuclease/exonuclease/phosphatase" CG10426 27-Aug-18 DroID_v2018_08 "Drer\inpp5e, Drer\ocrl, Drer\inppl1a, Drer\inpp5kb, Drer\inpp5ka, Drer\inpp5b, Drer\inpp5jb, Drer\sh2d1aa, Drer\inpp5j, Drer\inppl1b, Drer\inpp5d" "Scer\INP54, Scer\INP52, Scer\INP51, Scer\INP53" "Cele\cil-1, Cele\inpp-1" "Xtro\inpp5b, Xtro\inpp5k, Xtro\inpp5j, Xtro\inpp5d, Xtro\sec16a" "Mmus\Sh2d1b1, Mmus\Inpp5e, Mmus\Inpp5k, Mmus\Ocrl, Mmus\Sh2d1a, Mmus\Inpp5b, Mmus\Sh2d1b2, Mmus\Inpp5d, Mmus\Inpp5j, Mmus\Inppl1" "Hsap\INPP5K, Hsap\SH2D1B, Hsap\INPPL1, Hsap\INPP5E, Hsap\OCRL, Hsap\INPP5J, Hsap\INPP5B, Hsap\INPP5D" "neuroanatomy defective,viable" "anterior fascicle & synapse,synapse,intersegmental nerve" FBgn0025002 E(var)70-2 E(var)70-2 http://flybase.org/reports/FBgn0025002 - gene - - - E(var)70-2 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065230 l(2)SH2183 lethal (2) SH2183 http://flybase.org/reports/FBgn0065230 gene - - - "l(2)SH2183, l(2)SH2 2183" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0002795 ms(1)3 male sterile (1) 3 http://flybase.org/reports/FBgn0002795 - gene - - - ms(1)3 - - 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,female fertile" FBgn0085683 CG41552 - http://flybase.org/reports/FBgn0085683 protein_coding_gene - - - CG41552 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034957 CG3121 - http://flybase.org/reports/FBgn0034957 protein_coding_gene microtubule binding ; GO:0008017 | inferred from sequence or structural similarity microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity "anon-WO0140519.109, CG3121" IPR006802:Radial spokehead-like protein CG3121 27-Aug-18 DroID_v2018_08 Drer\rsph4a - - Xtro\rsph6a "Mmus\Rsph6a, Mmus\Rsph4a" "Hsap\RSPH6A, Hsap\RSPH4A" viable FBgn0034976 CG4049 - http://flybase.org/reports/FBgn0034976 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000330 - - "BEST:LD04705, CG4049, Arip4" "IPR000330:SNF2-related, N-terminal domain, IPR001650:Helicase, C-terminal, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR014001:Helicase superfamily 1/2, ATP-binding domain" CG4049 27-Aug-18 DroID_v2018_08 "Drer\rad54l2, Drer\atrx" Scer\RAD54 "Cele\rad-26, Cele\xnp-1" "Xtro\atrx, Xtro\rad54l2" "Mmus\Atrx, Mmus\Rad54l2" Hsap\RAD54L2 viable FBgn0050200 tRNA:Ala-CGC-1-3 transfer RNA:Alanine-CGC 1-3 http://flybase.org/reports/FBgn0050200 tRNA_gene GCG codon-amino acid adaptor activity ; GO:0033456 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033456 cytosol ; GO:0005829 | inferred by curator from GO:0033456 "CR30200, AE002575.trna8-AlaCGC, tRNA:A:CGC:AE002575-c, tRNA[[Ala]], chr2R.trna52-AlaCGC, tRNA-Ala-CGC-1-3, tRNA:Ala-CGC-1-3, tRNA:CR30200, GCG" - CR30200 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039471 CG6295 - http://flybase.org/reports/FBgn0039471 protein_coding_gene phosphatidylcholine 1-acylhydrolase activity ; GO:0008970 | inferred from electronic annotation with InterPro:IPR002334 lipase activity ; GO:0016298 | inferred from sequence or structural similarity with MGI:MGI:96820 lipid catabolic process ; GO:0016042 | inferred from sequence or structural similarity with MGI:MGI:96820 cellular_component ; GO:0005575 | no biological data available "CG6295, DmelL6" "IPR000734:Triacylglycerol lipase family, IPR002334:Vespid venom allergen phospholipase A1, IPR013818:Lipase/vitellogenin, IPR033906:Lipase, N-terminal, IPR029058:Alpha/Beta hydrolase fold" CG6295 27-Aug-18 DroID_v2018_08 "Drer\pla1a, Drer\lipca, Drer\lpl, Drer\LOC101884800, Drer\LOC100331214, Drer\lipg, Drer\lipia, Drer\lipib" - - "Xtro\lipg, Xtro\lpl" "Mmus\Pnliprp2, Mmus\Lipi, Mmus\Pnliprp1, Mmus\Pnlip, Mmus\Liph, Mmus\Lpl, Mmus\Lipg, Mmus\Pla1a, Mmus\Lipc" "Hsap\LIPC, Hsap\LIPH, Hsap\PNLIPRP3, Hsap\PNLIPRP2, Hsap\PLA1A, Hsap\LIPI, Hsap\PNLIP, Hsap\PNLIPRP1, Hsap\LIPG, Hsap\LPL" viable DRSC16012 K -0.112804712 0.279279894 -0.369200931 0.283664843 1.236918231 2.104315067 FBgn0085544 CG40955 - http://flybase.org/reports/FBgn0085544 protein_coding_gene - - - CG40955 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0029712 CG15912 - http://flybase.org/reports/FBgn0029712 protein_coding_gene hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR006439 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR006439 - "CG15912, 24639695" "IPR006439:HAD hydrolase, subfamily IA, IPR011949:HAD-superfamily hydrolase, subfamily IA, REG-2-like, IPR023214:HAD-like domain" CG15912 27-Aug-18 DroID_v2018_08 "Drer\hdhd3, Drer\nanp, Drer\ephx2" Scer\YMR130W Cele\K01G5.10 "Xtro\hdhd3, Xtro\nanp, Xtro\ephx2, Xtro\acad10" "Mmus\Nanp, Mmus\Hdhd3, Mmus\Acad10, Mmus\Ephx2" "Hsap\NANP, Hsap\EPHX2, Hsap\ACAD10, Hsap\HDHD3" viable FBgn0038873 CG5892 - http://flybase.org/reports/FBgn0038873 protein_coding_gene "transferase activity, transferring acyl groups other than amino-acyl groups ; GO:0016747 | inferred from electronic annotation with InterPro:IPR002656" - - CG5892 "IPR002656:Acyltransferase 3, IPR006621:Nose resistant-to-fluoxetine protein, N-terminal" CG5892 27-Aug-18 DroID_v2018_08 Drer\oacyl - "Cele\oac-31, Cele\oac-39, Cele\rhy-1, Cele\oac-5, Cele\oac-46, Cele\oac-53, Cele\oac-32, Cele\oac-50, Cele\ndg-4, Cele\oac-3, Cele\nrf-6, Cele\oac-14, Cele\oac-7, Cele\oac-55, Cele\oac-20, Cele\oac-6, Cele\oac-54, Cele\oac-9" Xtro\LOC101732251 Mmus\Oacyl - "viable,fertile" FBgn0015849 anon-10Cb anon-10Cb http://flybase.org/reports/FBgn0015849 - gene - - - anon-10Cb - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0261389 p1130 - http://flybase.org/reports/FBgn0261389 gene - - - p1130 - - 27-Aug-18 DroID_v2018_08 - - - - - - "stress response defective,long lived,dominant" FBgn0033875 CG6357 - http://flybase.org/reports/FBgn0033875 protein_coding_gene cysteine-type peptidase activity ; GO:0008234 | inferred from electronic annotation with InterPro:IPR013128 - - CG6357 "IPR013201:Cathepsin propeptide inhibitor domain (I29), IPR013128:Peptidase C1A" CG6357 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-267n13.1, Drer\ctsll, Drer\MGC174155, Drer\ctsl.1, Drer\LOC100536033, Drer\ctss2.1, Drer\ctsba, Drer\ctsk, Drer\ctsc, Drer\ctsh, Drer\ctss2.2, Drer\si:dkey-269i1.4, Drer\ctsbb, Drer\si:dkey-239j18.2, Drer\si:dkey-183k8.2, Drer\LOC100333521, Drer\ctslb, Drer\ctsz, Drer\zgc:174855, Drer\cts12, Drer\zgc:174153, Drer\wu:fa26c03, Drer\ctsla, Drer\si:dkey-239j18.3, Drer\si:dkey-228a15.1, Drer\ctss1, Drer\zgc:103438, Drer\zgc:110239" - - "Xtro\ctsl, Xtro\ctsv, Xtro\ctsb, Xtro\LOC100490139, Xtro\ctsz, Xtro\ctss, Xtro\LOC100498238, Xtro\ctsc, Xtro\ctsh" "Mmus\Cts3, Mmus\Ctsb, Mmus\Ctsr, Mmus\Tpbpa, Mmus\Ctsk, Mmus\Ctsz, Mmus\Cts8, Mmus\Ctsm, Mmus\Ctsq, Mmus\4930486L24Rik, Mmus\Ctsh, Mmus\Ctss, Mmus\Cts6, Mmus\Ctsc, Mmus\Ctsl, Mmus\Ctsll3, Mmus\Ctsj, Mmus\Cts7, Mmus\Ctla2b, Mmus\BC051665, Mmus\Tpbpb, Mmus\Ctla2a" "Hsap\CTSZ, Hsap\CTSB, Hsap\CTSC, Hsap\CTSH, Hsap\CTSL, Hsap\CTSV, Hsap\CTSK, Hsap\CTSS" viable FBgn0022318 l(1)B8.5 lethal (1) B8.5 http://flybase.org/reports/FBgn0022318 - gene - - - "B8.5, l(1)B8.5" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0010636 l(2)07129 lethal (2) 07129 http://flybase.org/reports/FBgn0010636 - gene - - - l(2)07129 - - 27-Aug-18 DroID_v2018_08 - - - - - - partially lethal - majority die FBgn0037454 CG1137 - http://flybase.org/reports/FBgn0037454 protein_coding_gene - - - "anon-WO0118547.86, CG1137" "IPR000048:IQ motif, EF-hand binding site" CG1137 27-Aug-18 DroID_v2018_08 Drer\iqcd - - Xtro\iqcd Mmus\Iqcd Hsap\IQCD viable FBgn0260617 2L1748 - http://flybase.org/reports/FBgn0260617 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L1748 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0000971 Fs(2)Him Female sterile (2) Himca http://flybase.org/reports/FBgn0000971 - gene - - - "Himca, Fs(2)Sz5, Fs(2)Him" - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile germline-dependent,dominant" egg FBgn0044056 Gpal Gpal http://flybase.org/reports/FBgn0044056 gene DNA binding ; GO:0003677 | inferred from direct assay - nucleus ; GO:0005634 | inferred from direct assay "GPAL, Gpal" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0015034 Cyp4e1 Cytochrome P450-4e1 http://flybase.org/reports/FBgn0015034 FBgn0033293 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "4e1, CYP4E1, P450, P-450, CG2062, Cyp4e1, CYP4e1" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG2062 27-Aug-18 DroID_v2018_08 "Drer\cyp46a1.1, Drer\cyp3c4, Drer\cyp20a1, Drer\cyp26c1, Drer\cyp46a1.4, Drer\cyp26b1, Drer\cyp4v8, Drer\cyp4f3, Drer\cyp3a65, Drer\cyp19a1a, Drer\cyp26a1, Drer\cyp3c2, Drer\cyp3c1, Drer\cyp4v7, Drer\cyp46a1.3, Drer\cyp46a1.2, Drer\LOC100329425, Drer\cyp4t8, Drer\cyp3c3, Drer\cyp19a1b" "Scer\ERG5, Scer\DIT2" "Cele\cyp-29A4, Cele\cyp-25A4, Cele\cyp-29A2, Cele\cyp-13A7, Cele\cyp-37A1, Cele\cyp-13A1, Cele\cyp-13A5, Cele\cyp-13A12, Cele\cyp-25A3, Cele\cyp-13A3, Cele\cyp-13A11, Cele\cyp-13A8, Cele\cyp-31A2, Cele\cyp-13A10, Cele\cyp-37B1, Cele\cyp-31A5, Cele\cyp-32B1, Cele\cyp-29A3, Cele\cyp-25A1, Cele\cyp-42A1, Cele\cyp-31A3, Cele\cyp-25A2, Cele\cyp-13A4, Cele\cyp-32A1" "Xtro\cyp20a1, Xtro\cyp4v2, Xtro\cyp26c1, Xtro\cyp26a1, Xtro\cyp4b1, Xtro\cyp4b1.2, Xtro\mgc108213, Xtro\cyp4f2, Xtro\LOC100488227, Xtro\cyp4f22, Xtro\cyp19a1, Xtro\cyp26b1, Xtro\LOC100487918" "Mmus\Cyp3a41b, Mmus\Cyp4b1, Mmus\Cyp26a1, Mmus\Cyp4a30b, Mmus\Cyp4f15, Mmus\Cyp19a1, Mmus\Cyp4f14, Mmus\Cyp3a16, Mmus\Cyp4a14, Mmus\Cyp4f13, Mmus\Cyp4f17, Mmus\Cyp3a41a, Mmus\Cyp4a29, Mmus\Cyp4a12b, Mmus\Cyp4f39, Mmus\Cyp3a59, Mmus\Cyp4f16, Mmus\Cyp3a25, Mmus\Cyp26b1, Mmus\Cyp3a11, Mmus\Cyp26c1, Mmus\Cyp4f18, Mmus\Cyp3a57, Mmus\Cyp46a1, Mmus\Cyp20a1, Mmus\Cyp4v3, Mmus\Cyp3a44, Mmus\Cyp4a32, Mmus\Cyp3a13, Mmus\Cyp4a12a, Mmus\Cyp4f37, Mmus\Cyp4f40, Mmus\Cyp4x1, Mmus\Cyp4a10, Mmus\Cyp4a31" "Hsap\CYP20A1, Hsap\CYP4A22, Hsap\CYP46A1, Hsap\CYP4F22, Hsap\CYP4F12, Hsap\CYP4B1, Hsap\CYP3A43, Hsap\CYP3A7, Hsap\CYP26A1, Hsap\CYP4F11, Hsap\CYP19A1, Hsap\CYP4A11, Hsap\CYP3A4, Hsap\CYP4V2, Hsap\CYP4F3, Hsap\CYP3A5, Hsap\CYP4X1, Hsap\CYP4F2, Hsap\CYP26B1, Hsap\CYP4Z1, Hsap\CYP4F8, Hsap\CYP26C1" viable FBgn0004590 Eig71Ec Ecdysone-induced gene 71Ec http://flybase.org/reports/FBgn0004590 - protein_coding_gene - metamorphosis ; GO:0007552 | inferred from expression pattern defense response to bacterium ; GO:0042742 | inferred from sequence or structural similarity with MGI:MGI:94880 extracellular region ; GO:0005576 | inferred from sequence model "L71-3, L71, III, gene III, gene-III, CG7608, Eig71Ec, LP11175p, Eig 71Ec" IPR003475:Insect protein of unknown function CG7608 27-Aug-18 DroID_v2018_08 - - Cele\W08F4.10 - - - viable FBgn0065796 l(2)SH0416 lethal (2) SH0416 http://flybase.org/reports/FBgn0065796 gene - - - l(2)SH0416 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0029690 CG6414 - http://flybase.org/reports/FBgn0029690 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from biological aspect of ancestor with PANTHER:PTN000168392 - - CG6414 "IPR002018:Carboxylesterase, type B, IPR019819:Carboxylesterase type B, conserved site, IPR019826:Carboxylesterase type B, active site, IPR029058:Alpha/Beta hydrolase fold" CG6414 27-Aug-18 DroID_v2018_08 "Drer\nlgn4a, Drer\ces2, Drer\ces3, Drer\nlgn3b, Drer\nlgn2a, Drer\nlgn3a, Drer\si:ch211-93f2.1, Drer\nlgn1, Drer\cel.1, Drer\cell, Drer\nlgn2b, Drer\nlgn4b" - "Cele\K11G9.2, Cele\F15A8.6, Cele\T07H6.1, Cele\E01G6.3, Cele\T22D1.11, Cele\K11G9.1, Cele\C42D4.2, Cele\C17H12.4, Cele\Y71H2AM.13, Cele\C01B10.4, Cele\C01B10.10, Cele\C23H4.2, Cele\R173.3, Cele\C52A10.1, Cele\F07C4.12, Cele\ZC376.1, Cele\ZK994.1, Cele\ZC376.3, Cele\T28C12.5, Cele\T02B5.1, Cele\T28C12.4, Cele\ZC376.2, Cele\F56C11.6, Cele\F13H6.3, Cele\C23H4.4, Cele\ges-1, Cele\C23H4.3, Cele\C23H4.7, Cele\K11G9.3, Cele\T02B5.3" "Xtro\nlgn3, Xtro\nlgn2, Xtro\ces2, Xtro\ces3, Xtro\bche, Xtro\nlgn4x, Xtro\cel, Xtro\LOC100494782" "Mmus\Ces1h, Mmus\Ces1c, Mmus\Ces2b, Mmus\Ces4a, Mmus\Ces1b, Mmus\Ces1e, Mmus\Ces3b, Mmus\Ces5a, Mmus\Ces1f, Mmus\Ces2g, Mmus\Ces2f, Mmus\Ces1g, Mmus\Nlgn1, Mmus\Ces2a, Mmus\Cel, Mmus\Ces3a, Mmus\Ces1d, Mmus\Nlgn2, Mmus\Ces1a, Mmus\Ces2e, Mmus\Ces2c, Mmus\Nlgn3, Mmus\Ces2h" "Hsap\CES2, Hsap\CES3, Hsap\NLGN1, Hsap\CES5A, Hsap\CES4A, Hsap\NLGN4Y, Hsap\NLGN2, Hsap\NLGN3, Hsap\CES1, Hsap\NLGN4X, Hsap\CEL" viable FBgn0065696 l(2)SH0636 lethal (2) SH0636 http://flybase.org/reports/FBgn0065696 gene - - - "l(2)SH0636, l(2)SH2 0636" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0001401 l(1)2Fd lethal (1) 2Fd http://flybase.org/reports/FBgn0001401 - gene - - - "l26, D82, l(1)EC226, N11, EC226, N6, l(1)N8, l(1)N11, l(1)2Fd" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,cell lethal,germline clone,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0265797 lncRNA:CR44586 - http://flybase.org/reports/FBgn0265797 non_protein_coding_gene - - - CR44586 - CR44586 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260086 2L3910 - http://flybase.org/reports/FBgn0260086 gene - - - 2L3910 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" "embryonic/larval dorsal trunk,somatic clone" FBgn0017430 Nelf-E Negative elongation factor E http://flybase.org/reports/FBgn0017430 - protein_coding_gene RNA binding ; GO:0003723 | inferred from direct assay mRNA binding ; GO:0003729 | inferred from sequence or structural similarity "neurogenesis ; GO:0022008 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter during mitosis ; GO:0007070 | inferred from direct assay negative regulation of transcription elongation from RNA polymerase II promoter ; GO:0034244 | inferred from direct assay positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype transcription elongation from RNA polymerase II promoter ; GO:0006368 | inferred from direct assay negative regulation of DNA-templated transcription, elongation ; GO:0032785 | inferred from direct assay negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype" NELF complex ; GO:0032021 | inferred from physical interaction with TH1 nucleus ; GO:0005634 | inferred from direct assay transcriptional repressor complex ; GO:0017053 | inferred from direct assay transcription elongation factor complex ; GO:0008023 | inferred from physical interaction with UniProtKB:Q24134 "NELF, NELF-E, CG5994, anon-66Da, cg5994, Nelf-E, dNelf-E, Nelf-e, NelfE" "IPR000504:RNA recognition motif domain, IPR034637:Negative elongation factor E, RNA recognition motif, IPR033102:Negative elongation factor E" CG5994 27-Aug-18 DroID_v2018_08 Drer\nelfe - - Xtro\nelfe Mmus\Nelfe "Hsap\RBFOX1, Hsap\NELFE" pupal stage&&adult stage "visible,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,germline clone,maternal effect" "wing,adult thorax,adult head,ommatidium,second segment of antenna,third segment of antenna,arista,tarsal segment,embryonic/larval hemocyte | third instar larval stage,ganglion mother cell,trichogen cell" FBgn0036828 CG6841 - http://flybase.org/reports/FBgn0036828 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:15860 "regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000000259 inferred from sequence or structural similarity with protein_id:BAA37140 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000000259 neurogenesis ; GO:0022008 | inferred from mutant phenotype" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay nucleus ; GO:0005634 | inferred by curator from GO:0000381 small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from sequence or structural similarity with protein_id:BAA37140 precatalytic spliceosome ; GO:0071011 | inferred from direct assay "Prp6, BcDNA:LD43276, CG6841" "IPR003107:HAT (Half-A-TPR) repeat, IPR010491:PRP1 splicing factor, N-terminal, IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR027108:Pre-mRNA-processing factor 6/Prp1/STA1, IPR019734:Tetratricopeptide repeat" CG6841 27-Aug-18 DroID_v2018_08 Drer\prpf6 "Scer\UTP6, Scer\PRP6" Cele\prp-6 Xtro\prpf6 Mmus\Prpf6 Hsap\PRPF6 "lethal,neuroanatomy defective,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,antenna,tarsal segment,unguis,pulvillus" DRSC21773 IE 0.391715312 2.018223583 1.4341235 2.519244203 -0.377498115 -1.230411843 FBgn0051288 CG31288 - http://flybase.org/reports/FBgn0051288 protein_coding_gene - - - "CG13665, CG31288" "IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain, IPR015897:CHK kinase-like" CG31288 27-Aug-18 DroID_v2018_08 Drer\LOC100150280 - "Cele\F59B1.10, Cele\nhr-246, Cele\C29F7.2, Cele\H06H21.8, Cele\F20D6.5, Cele\F59B1.8, Cele\C29F7.1" - - - viable FBgn0283432 CG46275 - http://flybase.org/reports/FBgn0283432 protein_coding_gene molecular_function ; GO:0003674 | no biological data available microtubule-based movement ; GO:0007018 | inferred from electronic annotation with InterPro:IPR025956 cytoplasmic dynein complex ; GO:0005868 | inferred from electronic annotation with InterPro:IPR025956 "CG46275, SdicA" "IPR001680:WD40 repeat, IPR025956:Cytoplasmic dynein 1 intermediate chain 1/2, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG46275 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267740 asRNA:CR46071 - http://flybase.org/reports/FBgn0267740 non_protein_coding_gene - - - "CR46071, Mgn635" - CR46071 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040392 CG14050 - http://flybase.org/reports/FBgn0040392 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR003656 - - "H48C10.1, EG:BACH48C10.1, CG14050" "IPR003656:Zinc finger, BED-type" CG14050 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0043074 HF-BXC Homing Fragment http://flybase.org/reports/FBgn0043074 region - - - HF-BXC - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030259 CG1545 - http://flybase.org/reports/FBgn0030259 protein_coding_gene - - - "anon-EST:Posey256, BcDNA:GH01560, CG1545" - CG1545 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0260967 CG42590 - http://flybase.org/reports/FBgn0260967 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42590 - CG42590 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0043365 EP2146a EP2146a http://flybase.org/reports/FBgn0043365 gene - - - "EP(2)2146, EP2146a" - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "scutellar bristle,tormogen cell,trichogen cell,ectopic,embryonic/larval salivary gland" FBgn0005376 x6 x6 http://flybase.org/reports/FBgn0005376 - gene - - - x6 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260101 2L0128 - http://flybase.org/reports/FBgn0260101 gene - - - 2L0128 - - 27-Aug-18 DroID_v2018_08 - - - - - - "embryonic/larval dorsal trunk,somatic clone" FBgn0051963 tRNA:Trp-CCA-2-1 transfer RNA:Tryptophan-CCA 2-1 http://flybase.org/reports/FBgn0051963 tRNA_gene UGG codon-amino acid adaptor activity ; GO:0033416 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033416 cytosol ; GO:0005829 | inferred by curator from GO:0033416 "AE002638.trna1-TrpCCA, tRNA:W:CCA:AE002638, CR31963, chr2L.trna34-TrpCCA, tRNA-Trp-CCA-2-1, tRNA:Trp-CCA-2-1, tRNA:CR31963, UGG" - CR31963 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031770 CG13995 - http://flybase.org/reports/FBgn0031770 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from electronic annotation with InterPro:IPR000276 G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity neuropeptide receptor activity ; GO:0008188 | inferred from sequence model G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR000276 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR017452 integral component of membrane ; GO:0016021 | inferred from sequence model integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity" "anon-WO0170980.170, anon-WO0170980.169, CG13995" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG13995 27-Aug-18 DroID_v2018_08 Drer\cckar - "Cele\srv-29, Cele\srv-28, Cele\ZK863.1, Cele\srv-25, Cele\srv-24, Cele\srv-27, Cele\srv-19, Cele\ops-1, Cele\C50H11.13, Cele\ntr-1, Cele\srv-30, Cele\srv-32, Cele\srv-22, Cele\srv-26, Cele\C04C3.6, Cele\ntr-2, Cele\srv-21, Cele\T01B11.1, Cele\C54E10.3, Cele\srv-31, Cele\srv-17" - - - viable FBgn0038515 CG5823 - http://flybase.org/reports/FBgn0038515 protein_coding_gene ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with SGD:S000000902 ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 "cuticle development ; GO:0042335 | inferred from genetic interaction with UniProtKB:Q0KHR3,UniProtKB:Q9VX75,UniProtKB:X2JCB3,UniProtKB:X2JFU8 protein polyubiquitination ; GO:0000209 | inferred from biological aspect of ancestor with PANTHER:PTN000630005 ER-associated ubiquitin-dependent protein catabolic process ; GO:0030433 | inferred from biological aspect of ancestor with PANTHER:PTN000630005 protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with SGD:S000000902 ER-associated ubiquitin-dependent protein catabolic process ; GO:0030433 | inferred from sequence or structural similarity with SGD:S000000902" endoplasmic reticulum membrane ; GO:0005789 | inferred from sequence or structural similarity with SGD:S000000902 endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000630005 CG5823 "IPR000608:Ubiquitin-conjugating enzyme E2, IPR016135:Ubiquitin-conjugating enzyme/RWD-like" CG5823 27-Aug-18 DroID_v2018_08 Drer\ube2j2 Scer\UBC6 "Cele\ubc-15, Cele\ubc-26" Xtro\ube2j2 Mmus\Ube2j2 Hsap\UBE2J2 "viable,fertile" FBgn0001663 l(1)E34 lethal (1) E34 http://flybase.org/reports/FBgn0001663 - gene - - - "l(1)E34[ts], l(1)E34" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,heat sensitive,some die during pupal stage" FBgn0051664 CG31664 - http://flybase.org/reports/FBgn0051664 protein_coding_gene - - - "CG15622, CG31664" IPR032062:Protein of unknown function DUF4803 CG31664 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0069161 mcl(3)Z1956 mcl(3)Z1956 http://flybase.org/reports/FBgn0069161 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z1956 - - 27-Aug-18 DroID_v2018_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0085223 CG34194 - http://flybase.org/reports/FBgn0085223 protein_coding_gene serine C-palmitoyltransferase activity ; GO:0004758 | contributes_to inferred from sequence or structural similarity with HGNC:20361 biological_process ; GO:0008150 | no biological data available serine C-palmitoyltransferase complex ; GO:0017059 | inferred from sequence or structural similarity with HGNC:20361 CG34194 IPR024512:Small subunit of serine palmitoyltransferase-like CG34194 27-Aug-18 DroID_v2018_08 "Drer\sptssa, Drer\sptssb" - Cele\F13H10.8 "Xtro\sptssb, Xtro\sptssa" "Mmus\Sptssa, Mmus\Sptssb" "Hsap\SPTSSB, Hsap\SPTSSA" FBgn0033440 CG10459 - http://flybase.org/reports/FBgn0033440 protein_coding_gene receptor binding ; GO:0005102 | inferred from sequence or structural similarity with MGI:MGI:1329037 negative regulation of transforming growth factor beta receptor signaling pathway ; GO:0030512 | inferred from sequence or structural similarity with MGI:MGI:1329037 cellular_component ; GO:0005575 | no biological data available CG10459 "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat" CG10459 27-Aug-18 DroID_v2018_08 Drer\strap Scer\TIF34 - Xtro\strap Mmus\Strap "Hsap\STRAP, Hsap\FBXW9" viable DRSC05991 K -0.746006084 0.843134801 -0.254654608 0.096453341 -1.534710026 0.721058438 FBgn0011177 l(1)291-68 lethal (1) 291-68 http://flybase.org/reports/FBgn0011177 FBgn0010199 gene - - - "291-68, l(1)291-68" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0259397 EP-297.2 - http://flybase.org/reports/FBgn0259397 gene - - - EP-297.2 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible wing vein FBgn0013284 Jhbp-80 Juvenile hormone binding protein - 80kD http://flybase.org/reports/FBgn0013284 - gene - - - Jhbp-80 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000746 fs(1)A321 female sterile (1) A321 http://flybase.org/reports/FBgn0000746 - gene - - - fs(1)A321 - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive,visible" "egg,macrochaeta" FBgn0020821 l(3)98Di lethal (3) 98Di http://flybase.org/reports/FBgn0020821 - gene - - - "M311, l(3)98Di" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0020345 Clch Chloride channel http://flybase.org/reports/FBgn0020345 - gene - - - "anon-49ABa, Clch" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001612 Grip91 Gamma-tubulin ring protein 91 http://flybase.org/reports/FBgn0001612 "FBgn0026429, FBgn0040196, FBgn0066830" protein_coding_gene structural constituent of cytoskeleton ; GO:0005200 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 microtubule binding ; GO:0008017 | inferred from sequence or structural similarity microtubule minus-end binding ; GO:0051011 | contributes_to inferred from direct assay gamma-tubulin binding ; GO:0043015 | inferred from direct assay microtubule nucleation ; GO:0007020 | inferred from direct assay male meiosis ; GO:0007140 | inferred from mutant phenotype mitotic spindle assembly ; GO:0090307 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 neurogenesis ; GO:0022008 | inferred from mutant phenotype centrosome organization ; GO:0051297 | inferred from mutant phenotype microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity centrosome duplication ; GO:0051298 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 interphase microtubule nucleation by interphase microtubule organizing center ; GO:0051415 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 cytoplasmic microtubule organization ; GO:0031122 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 meiotic spindle organization ; GO:0000212 | inferred from mutant phenotype spindle pole ; GO:0000922 | inferred from electronic annotation with InterPro:IPR007259 equatorial microtubule organizing center ; GO:0000923 | inferred from biological aspect of ancestor with PANTHER:PTN000447085 gamma-tubulin small complex ; GO:0008275 | inferred from physical interaction with Grip84 inferred from physical interaction with γTub23C gamma-tubulin small complex ; GO:0008275 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity centrosome ; GO:0005813 | colocalizes_with inferred from direct assay mitotic spindle ; GO:0072686 | colocalizes_with inferred from direct assay "Dgrip91, Dgrips91, dd4, GCP3, dGRIP91, GRIP91, CG10988, l(1)d.deg.-4, l(1)d deg-4, l(1)d.deg.4, l(1)G0122, anon-WO03040301.197, Dgrip9, DGrip91, Grip91, Dd4, l(1)dd4" IPR007259:Gamma-tubulin complex component protein CG10988 27-Aug-18 DroID_v2018_08 "Drer\tubgcp2, Drer\tubgcp4, Drer\tubgcp6, Drer\tubgcp3" Scer\SPC98 - "Xtro\tubgcp6, Xtro\tubgcp2, Xtro\tubgcp4, Xtro\tubgcp3" "Mmus\Tubgcp3, Mmus\Tubgcp6, Mmus\Tubgcp2, Mmus\Tubgcp4" "Hsap\TUBGCP4, Hsap\TUBGCP3, Hsap\TUBGCP2, Hsap\TUBGCP6" embryonic stage "wild-type,mitotic cell cycle defective,lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage,meiotic cell cycle defective,male limited,male sterile,cytokinesis defective,female sterile,visible,partially lethal - majority live,sterile,partially,neuroanatomy defective" "imaginal disc,cell cycle,embryonic/larval brain,mitotic cell cycle,centriole,pericentriolar material,centrosome,spermatocyte & spindle,wing,head bristle,adult thorax & macrochaeta,scutellar bristle,adult abdomen,macrochaeta,abdominal segment,ganglion mother cell,chaeta,supernumerary" DRSC20249 IE 2.294466383 0.74518313 1.954009186 0.180643229 -0.063889585 1.153351715 FBgn0261596 RpS24 Ribosomal protein S24 http://flybase.org/reports/FBgn0261596 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from direct assay "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR001976, InterPro:IPR012678 cytoplasmic translation ; GO:0002181 | traceable author statement cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000462 | inferred from biological aspect of ancestor with PANTHER:PTN000052028" ribosome ; GO:0005840 | inferred from direct assay cytosolic ribosome ; GO:0022626 | inferred from direct assay cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement "RpS24, CG3751, S24, BcDNA:RE59324, l(2)SH2053, l(2)SH2 2053, Rp S24" "IPR018098:Ribosomal S24e conserved site, IPR001976:Ribosomal protein S24e, IPR012678:Ribosomal protein L23/L15e core domain" CG3751 27-Aug-18 DroID_v2018_08 Drer\rps24 "Scer\RPS24A, Scer\RPS24B" "Cele\rps-24, Cele\T07A9.14, Cele\T26G10.3" Xtro\rps24 Mmus\Rps24 Hsap\RPS24 DRSC28412 IEK -1.681035961 -2.296661036 1.00233819 -4.236716912 4.265953391 3.233140018 FBgn0029056 l(1)G0449 lethal (1) G0449 http://flybase.org/reports/FBgn0029056 gene - - - l(1)G0449 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" third instar larva FBgn0034563 CG15649 - http://flybase.org/reports/FBgn0034563 protein_coding_gene - - - "CG15649, BcDNA:GH08880" - CG15649 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible,body color defective,planar polarity defective" "chaeta,supernumerary,mesothoracic tergum" FBgn0261004 asl asterless http://flybase.org/reports/FBgn0261004 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Sas-4 negative regulation of centriole elongation ; GO:1903723 | inferred from mutant phenotype sperm axoneme assembly ; GO:0007288 | inferred from mutant phenotype centrosome organization ; GO:0051297 | inferred from mutant phenotype centriole replication ; GO:0007099 | inferred from mutant phenotype single fertilization ; GO:0007338 | inferred from mutant phenotype asymmetric cell division ; GO:0008356 | inferred from direct assay centrosome cycle ; GO:0007098 | inferred from mutant phenotype non-motile cilium assembly ; GO:1905515 | inferred from mutant phenotype pericentriolar material ; GO:0000242 | inferred from direct assay centriole ; GO:0005814 | inferred from direct assay centriole ; GO:0005814 | colocalizes_with inferred from direct assay ciliary basal body ; GO:0036064 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay "Asl, ASL, asl, CG2919, sdu, mecD" - CG2919 27-Aug-18 DroID_v2018_08 - Scer\SLK19 Cele\F18H3.4 - - - FBgn0026156 wlf wolf http://flybase.org/reports/FBgn0026156 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available wlf - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0022399 Gase3 Gastric serine protease 3 http://flybase.org/reports/FBgn0022399 - gene - - - Gase3 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0067634 233y-a 233y-a http://flybase.org/reports/FBgn0067634 gene - - - "233y, 233y-a" - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile,courtship behavior defective,female" FBgn0264261 lncRNA:CR43761 - http://flybase.org/reports/FBgn0264261 non_protein_coding_gene - - - "CR43761, lincRNA.155" - CR43761 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263892 l(3)GL45 - http://flybase.org/reports/FBgn0263892 gene - - - l(3)GL45 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,cell cycle defective,somatic clone" "embryonic/larval brain,somatic clone,embryonic/larval neuroblast" FBgn0061140 l(3)S000625b lethal (3) S000625b http://flybase.org/reports/FBgn0061140 gene - - - "0006/25, l(3)S000625b" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0262376 mir-219 mir-219 stem loop http://flybase.org/reports/FBgn0262376 miRNA_gene - - - "dme-mir-219, mir-219, MIR-219, CR42897, miR-219, CR33579" - CR42897 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,visible,lethal - all die before end of first instar larval stage,some die during first instar larval stage" "eye,wing,1st posterior cell" FBgn0036134 FoxK Forkhead box K http://flybase.org/reports/FBgn0036134 protein_coding_gene "sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001766, InterPro:IPR018122 RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN001371846" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001766, InterPro:IPR018122, InterPro:IPR030456 cellular response to virus ; GO:0098586 | inferred from mutant phenotype midgut development ; GO:0007494 | inferred from mutant phenotype defense response to virus ; GO:0051607 | inferred from mutant phenotype visceral mesoderm-endoderm interaction involved in midgut development ; GO:0007495 | inferred from mutant phenotype positive regulation of gene expression ; GO:0010628 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001371846 "CG11799, MNF, DmLD16137, DmMNF, FoxK, fork head transcription factor short isoform, fork head transcription factor long isoform, Mnf, dFoxK, fd68A" "IPR018122:Fork head domain conserved site1, IPR000253:Forkhead-associated (FHA) domain, IPR001766:Fork head domain, IPR008984:SMAD/FHA domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR030456:Fork head domain conserved site 2" CG11799 27-Aug-18 DroID_v2018_08 "Drer\foxl1, Drer\foxf2a, Drer\si:ch211-262e15.1, Drer\foxi2, Drer\zgc:113424, Drer\foxq1b, Drer\foxb2, Drer\foxk1, Drer\foxb1b, Drer\foxq2, Drer\si:rp71-45k5.2, Drer\foxk2, Drer\foxb1a, Drer\foxd2, Drer\foxj1a, Drer\foxd3, Drer\foxg1a" "Scer\HCM1, Scer\FKH2, Scer\FHL1, Scer\FKH1" "Cele\lin-31, Cele\pha-4, Cele\fkh-2, Cele\fkh-10, Cele\unc-130" "Xtro\foxd3, Xtro\foxi4.2, Xtro\foxb1, Xtro\foxd4l1.1, Xtro\foxj1.2, Xtro\foxj1, Xtro\foxd2, Xtro\foxq1, Xtro\foxh1, Xtro\foxk2" "Mmus\Foxj1, Mmus\Foxk1, Mmus\Foxg1, Mmus\Foxm1, Mmus\Foxb2, Mmus\Foxb1, Mmus\Foxk2, Mmus\Foxl1, Mmus\Foxq1, Mmus\Foxd3" "Hsap\FOXQ1, Hsap\AP5Z1, Hsap\FOXB1, Hsap\FOXG1, Hsap\FOXJ1, Hsap\FOXK1, Hsap\FOXD3, Hsap\FOXB2, Hsap\FOXK2, Hsap\FOXD4, Hsap\FOXL1" viable FBgn0033683 CG18343 - http://flybase.org/reports/FBgn0033683 protein_coding_gene - - - CG18343 - CG18343 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0035412 CG14957 - http://flybase.org/reports/FBgn0035412 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG14957 IPR002557:Chitin binding domain CG14957 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0023126 anon-10Acc anon-10Acc http://flybase.org/reports/FBgn0023126 - gene - - - "22, anon-10Acc" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0003376 Sgs6 Salivary gland secretion 6 http://flybase.org/reports/FBgn0003376 - gene - - - "sgs6, Sgs, Sgs-6, SGS-6, Sgs6" - - 27-Aug-18 DroID_v2018_08 - - - - - - larval stage | late third instar larval stage embryonic/larval salivary gland

FBgn0016778 anon-77Bb anon-77Bb http://flybase.org/reports/FBgn0016778 - gene - - - "C, anon-77Bb" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040815 CG14114 - http://flybase.org/reports/FBgn0040815 protein_coding_gene - - - CG14114 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085222 CG34193 - http://flybase.org/reports/FBgn0085222 protein_coding_gene - - - CG34193 - CG34193 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037911 CG10898 - http://flybase.org/reports/FBgn0037911 protein_coding_gene "hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR000086, InterPro:IPR015797, InterPro:IPR020084" - - "anon-WO0118547.280, CG10898" "IPR000086:NUDIX hydrolase domain, IPR015797:NUDIX hydrolase domain-like, IPR020084:NUDIX hydrolase, conserved site, IPR020476:NUDIX hydrolase" CG10898 27-Aug-18 DroID_v2018_08 "Drer\nudt6, Drer\nudt18" Scer\NPY1 Cele\ndx-1 Xtro\nudt18 Mmus\Nudt18 "Hsap\NUDT18, Hsap\NUDT6" "viable,fertile" FBgn0065391 l(2)SH1627 lethal (2) SH1627 http://flybase.org/reports/FBgn0065391 gene - - - "l(2)SH1627, l(2)SH2 1627" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0026211 l(4)102CDh lethal (4) 102CDh http://flybase.org/reports/FBgn0026211 - gene - - - "10, l(4)10, 102CDh, l(4)102CDh" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0005682 rdgD retinal degeneration D http://flybase.org/reports/FBgn0005682 - gene - - - rdgD - - 27-Aug-18 DroID_v2018_08 - - - - - - "eye,ommatidium,eye photoreceptor cell,retina" FBgn0267650 pre-mod(mdg4)-AA - http://flybase.org/reports/FBgn0267650 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "pre-mod(mdg4)-AA, CG45988" "IPR007588:Zinc finger, FLYWCH-type" CG45988 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0053405 5SrRNA:CR33405 5SrRNA:CR33405 http://flybase.org/reports/FBgn0053405 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33405, 5SrRNA:CR33405" - CR33405 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0277424 l(3)psg21 - http://flybase.org/reports/FBgn0277424 gene - - - "l(3)psg21, psg21" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005382 ggy groggy http://flybase.org/reports/FBgn0005382 - gene - - - ggy - - 27-Aug-18 DroID_v2018_08 - - - - - - "paralytic,temperature conditional,neurophysiology defective" FBgn0014120 anon-96Fe anon-96Fe http://flybase.org/reports/FBgn0014120 - gene - - - anon-96Fe - - 27-Aug-18 DroID_v2018_08 - - - - - - larval stage eye-antennal disc

FBgn0031037 CG14207 - http://flybase.org/reports/FBgn0031037 protein_coding_gene unfolded protein binding ; GO:0051082 | inferred from sequence model protein refolding ; GO:0042026 | inferred from direct assay chaperone-mediated protein folding ; GO:0061077 | inferred from sequence model Z disc ; GO:0030018 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay Z disc ; GO:0030018 | colocalizes_with inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay "Dmel21.3, CG14207, dHspB8, HspB8, Hsp20-like protein" "IPR001436:Alpha crystallin/Heat shock protein, IPR002068:Alpha crystallin/Hsp20 domain, IPR008978:HSP20-like chaperone, IPR031107:Small heat shock protein HSP20" CG14207 27-Aug-18 DroID_v2018_08 "Drer\hspb2, Drer\cryabb, Drer\cryaa, Drer\hspb8, Drer\hspb15, Drer\hspb7, Drer\hspb1, Drer\si:dkey-1k23.3, Drer\cryaba, Drer\hspb3, Drer\hspb9, Drer\hspb12, Drer\hspb11, Drer\hspb6" - "Cele\hsp-16.2, Cele\hsp-17, Cele\hsp-12.6, Cele\hsp-12.2, Cele\hsp-25" "Xtro\hsp30d, Xtro\hspb1, Xtro\uqcrh, Xtro\cryaa, Xtro\hspb8, Xtro\cryab, Xtro\hspb3, Xtro\hspb6, Xtro\hspb2" "Mmus\Cryab, Mmus\Hspb8, Mmus\Hspb9, Mmus\Hspb2, Mmus\Hspb6, Mmus\Hspb1, Mmus\Hspb7, Mmus\Hspb3, Mmus\Cryaa" "Hsap\CRYAB, Hsap\HSPB7, Hsap\HSPB1, Hsap\HSPB2, Hsap\CRYAA, Hsap\HSPB6, Hsap\HSPB8, Hsap\LOC102724652, Hsap\HSPB3, Hsap\HSPB9" "viable,lethal" FBgn0042201 Nplp3 Neuropeptide-like precursor 3 http://flybase.org/reports/FBgn0042201 protein_coding_gene neuropeptide hormone activity ; GO:0005184 | non-traceable author statement neuropeptide signaling pathway ; GO:0007218 | non-traceable author statement extracellular region ; GO:0005576 | non-traceable author statement "NPLP3, CG13061, CG18502, BcDNA:RH16169, Nplp3, nplp3, SHA, VVIamide" - CG13061 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" DRSC09944 I -0.938751205 1.582575417 0.183768495 0.563328418 -0.031505594 -0.422396686 FBgn0010093 Su(vg)E6 Suppressor of vestigial E6 http://flybase.org/reports/FBgn0010093 - gene - - - "vg[[EMS6]], Su(vg)E6" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0052582 lncRNA:CR32582 - http://flybase.org/reports/FBgn0052582 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG32582, BcDNA:SD27303, CR32582, mdcds_55373" - CR32582 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" FBgn0037680 pasi2 pasiflora 2 http://flybase.org/reports/FBgn0037680 protein_coding_gene - "establishment of endothelial barrier ; GO:0061028 | inferred from mutant phenotype septate junction assembly ; GO:0019991 | inferred from mutant phenotype regulation of tube length, open tracheal system ; GO:0035159 | inferred from mutant phenotype establishment of glial blood-brain barrier ; GO:0060857 | inferred from mutant phenotype" integral component of plasma membrane ; GO:0005887 | inferred from direct assay "dmCG8121, pasi2, CG8121" - CG8121 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0052100 CG32100 - http://flybase.org/reports/FBgn0052100 protein_coding_gene - gravitaxis ; GO:0042332 | inferred from mutant phenotype - "CG18638, CG10429, CG32100" - CG32100 27-Aug-18 DroID_v2018_08 - - - - - - "gravitaxis defective,viable" FBgn0267326 Ntl Neurotransmitter transporter-like http://flybase.org/reports/FBgn0267326 protein_coding_gene neurotransmitter:sodium symporter activity ; GO:0005328 | inferred from electronic annotation with InterPro:IPR000175 glycine transmembrane transporter activity ; GO:0015187 | inferred from sequence or structural similarity with HGNC:11051 inferred from mutant phenotype neurotransmitter transporter activity ; GO:0005326 | inferred from sequence or structural similarity with DAT L-proline transmembrane transporter activity ; GO:0015193 | inferred from sequence model neurotransmitter transport ; GO:0006836 | inferred from sequence or structural similarity with DAT glycine import ; GO:0036233 | inferred from mutant phenotype flagellated sperm motility ; GO:0030317 | inferred from mutant phenotype proline transport ; GO:0015824 | inferred from sequence model positive regulation of protein polyglycylation ; GO:1903346 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 "Ntl, ntl, CG7075, Mp" IPR000175:Sodium:neurotransmitter symporter CG7075 27-Aug-18 DroID_v2018_08 "Drer\slc6a18, Drer\slc6a4a, Drer\slc6a1l, Drer\slc6a16b, Drer\slc6a14, Drer\slc6a1b, Drer\slc6a19b, Drer\slc6a6b, Drer\slc6a13l, Drer\slc6a2, Drer\slc6a4b, Drer\slc6a9, Drer\slc6a16a, Drer\slc6a19a.2, Drer\si:ch211-132b12.6, Drer\slc6a5, Drer\slc6a8, Drer\si:ch211-132b12.2, Drer\slc6a1a, Drer\slc6a13, Drer\zgc:158225, Drer\si:ch211-132b12.1, Drer\si:ch211-117c9.5, Drer\slc6a15, Drer\slc6a6a, Drer\slc6a17, Drer\slc6a11a, Drer\slc6a13, Drer\slc6a19a.1" - "Cele\snf-3, Cele\snf-9, Cele\dat-1, Cele\snf-2, Cele\snf-12, Cele\snf-6, Cele\mod-5, Cele\snf-11" "Xtro\slc6a13, Xtro\LOC100127682, Xtro\slc6a15, Xtro\slc6a17, Xtro\slc6a7, Xtro\slc6a14.2, Xtro\slc6a3, Xtro\slc6a8, Xtro\slc6a6, Xtro\slc6a4, Xtro\slc6a9, Xtro\slc6a19, Xtro\slc6a16, Xtro\slc6a1, Xtro\slc6a5, Xtro\slc6a12, Xtro\slc6a2" "Mmus\Slc6a21, Mmus\Slc6a4, Mmus\Slc6a20b, Mmus\Slc6a8, Mmus\Slc6a6, Mmus\Slc6a18, Mmus\Slc6a13, Mmus\Slc6a15, Mmus\Slc6a12, Mmus\Slc6a9, Mmus\Slc6a16, Mmus\Slc6a2, Mmus\Slc6a20a, Mmus\Slc6a19, Mmus\Slc6a1, Mmus\Slc6a3, Mmus\Slc6a5, Mmus\Slc6a17, Mmus\Slc6a7, Mmus\Slc6a14, Mmus\Slc6a11" "Hsap\SLC6A1, Hsap\SLC6A16, Hsap\SLC6A3, Hsap\SLC6A13, Hsap\SLC6A8, Hsap\SLC6A20, Hsap\SLC6A6, Hsap\SLC6A14, Hsap\SLC6A17, Hsap\SLC6A12, Hsap\SLC6A15, Hsap\SLC6A18, Hsap\SLC6A4, Hsap\SLC6A2, Hsap\SLC6A5, Hsap\SLC6A7, Hsap\SLC6A9, Hsap\SLC6A19, Hsap\SLC6A11" FBgn0060664 l(3)S080906 lethal (3) S080906 http://flybase.org/reports/FBgn0060664 gene - - - "0809/06, l(3)S080906" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0260659 CG42542 - http://flybase.org/reports/FBgn0260659 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available - "CG42542, CG4196, CG31303" IPR001727:Gdt1 family CG42542 27-Aug-18 DroID_v2018_08 Drer\tmem165 Scer\GDT1 Cele\Y54F10AL.1 Xtro\tmem165 Mmus\Tmem165 Hsap\TMEM165 DRSC22264 I 1.116935161 2.92967633 0.981846972 1.068903056 0.844129052 -0.365539976 FBgn0265890 lncRNA:CR44679 - http://flybase.org/reports/FBgn0265890 non_protein_coding_gene - - - "CR44679, lincRNA.630" - CR44679 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0029061 l(1)G0372 lethal (1) G0372 http://flybase.org/reports/FBgn0029061 gene - - - l(1)G0372 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0025732 sca::Hsap\FGG sca::Hsap\FGG http://flybase.org/reports/FBgn0025732 - engineered_fusion_gene - - - sca::Hsap\FGG - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing,wing vein" FBgn0025563 anon-23Cc anon-23Cc http://flybase.org/reports/FBgn0025563 - gene - - - "c2.5, anon-23Cc" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0025764 l(3)89Df lethal (3) 89Df http://flybase.org/reports/FBgn0025764 - gene - - - "l(3)M2922, l(3)89Df" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0069312 X-206-23 X-206-23 http://flybase.org/reports/FBgn0069312 gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available X-206-23 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "embryonic/first instar larval cuticle,germline clone,maternal effect" FBgn0036689 CG7730 - http://flybase.org/reports/FBgn0036689 protein_coding_gene - learning or memory ; GO:0007611 | inferred from biological aspect of ancestor with PANTHER:PTN000473820 - CG7730 IPR031962:Domain of unknown function DUF4781 CG7730 27-Aug-18 DroID_v2018_08 - - Cele\F02C12.1 - - - viable FBgn0025634 CG13367 - http://flybase.org/reports/FBgn0025634 FBgn0013389 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000330972 "EG:115C2.8, anon-1BCb, CG13367" - CG13367 27-Aug-18 DroID_v2018_08 Drer\gatad1 - - Xtro\gatad1 Mmus\Gatad1 Hsap\GATAD1 " adult stage , embryonic stage " viable FBgn0263874 lncRNA:CR43721 - http://flybase.org/reports/FBgn0263874 non_protein_coding_gene - - - "CR43721, CG43268" - CR43721 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002541 ld loboid http://flybase.org/reports/FBgn0002541 - gene - - - ld - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,viable,reduced,dominant,partially" "eye,ommatidium" FBgn0263494 CR43483 - http://flybase.org/reports/FBgn0263494 pseudogene_attribute - - - CR43483 - CR43483 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032519 CG16957 - http://flybase.org/reports/FBgn0032519 protein_coding_gene heme binding ; GO:0020037 | inferred from biological aspect of ancestor with PANTHER:PTN000031653 heme binding ; GO:0020037 | inferred from sequence or structural similarity with SGD:S000006091 biological_process ; GO:0008150 | no biological data available endosome ; GO:0005768 | inferred from sequence or structural similarity with SGD:S000006091 endomembrane system ; GO:0012505 | inferred from biological aspect of ancestor with PANTHER:PTN000031541 membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN000031541 CG16957 IPR001199:Cytochrome b5-like heme/steroid binding domain CG16957 27-Aug-18 DroID_v2018_08 "Drer\pgrmc2, Drer\pgrmc1, Drer\nenf" Scer\DAP1 Cele\vem-1 "Xtro\nenf, Xtro\pgrmc1, Xtro\pgrmc2" "Mmus\Nenf, Mmus\Pgrmc1, Mmus\Pgrmc2" "Hsap\NENF, Hsap\PGRMC1, Hsap\PGRMC2" "viable,fertile" FBgn0029924 CG4586 - http://flybase.org/reports/FBgn0029924 protein_coding_gene "acyl-CoA dehydrogenase activity ; GO:0003995 | inferred from electronic annotation with InterPro:IPR006091 flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR012258, InterPro:IPR013786 acyl-CoA oxidase activity ; GO:0003997 | inferred from sequence or structural similarity with HGNC:119" fatty acid beta-oxidation ; GO:0006635 | inferred from sequence or structural similarity with HGNC:119 "peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:119,HGNC:120 inferred from sequence model" CG4586 "IPR002655:Acyl-CoA oxidase, C-terminal, IPR006091:Acyl-CoA oxidase/dehydrogenase, central domain, IPR009075:Acyl-CoA dehydrogenase/oxidase C-terminal, IPR009100:Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain, IPR012258:Acyl-CoA oxidase, IPR013786:Acyl-CoA dehydrogenase/oxidase, N-terminal, IPR029320:Acyl-coenzyme A oxidase, N-terminal" CG4586 27-Aug-18 DroID_v2018_08 "Drer\acox3, Drer\acox1" Scer\POX1 "Cele\acox-5, Cele\acox-1, Cele\acox-3, Cele\F59F4.1, Cele\acdh-13, Cele\acox-4, Cele\acox-2" "Xtro\acox1, Xtro\acox2" "Mmus\Acox2, Mmus\Acox1, Mmus\Acox3" "Hsap\ACOX2, Hsap\ACOX1, Hsap\ACOX3" "viable,fertile" FBgn0086068 snoRNA:Or-CD12 - http://flybase.org/reports/FBgn0086068 snoRNA_gene - - - "snoRNA:Or-CD12, orphan CD12, DmOr_cd12(DmU24), CR34697, DmU24, dM_28s.017" - CR34697 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0063413 l(3)3450-J lethal (3) 3450-J http://flybase.org/reports/FBgn0063413 gene - - - l(3)3450-J - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0015738 I-55 screen I - clone 55 http://flybase.org/reports/FBgn0015738 - gene - - - I-55 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065317 l(2)SH1924 lethal (2) SH1924 http://flybase.org/reports/FBgn0065317 gene - - - "l(2)SH1924, l(2)SH2 1924" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0065641 l(2)SH0759 lethal (2) SH0759 http://flybase.org/reports/FBgn0065641 gene - - - "l(2)SH0759, l(2)SH2 0759" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0014922 anon-72ABf anon-72ABf http://flybase.org/reports/FBgn0014922 - gene - - - anon-72ABf - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032001 CG8360 - http://flybase.org/reports/FBgn0032001 protein_coding_gene cytidine deaminase activity ; GO:0004126 | inferred from biological aspect of ancestor with PANTHER:PTN000182087 zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000182087 cytidine deamination ; GO:0009972 | inferred from biological aspect of ancestor with PANTHER:PTN000182087 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000182087 "BcDNA:LP03131, CG8360" "IPR002125:Cytidine and deoxycytidylate deaminases, zinc-binding, IPR006262:Cytidine deaminase, homotetrameric, IPR016193:Cytidine deaminase-like" CG8360 27-Aug-18 DroID_v2018_08 "Drer\zgc:103586, Drer\cda" Scer\CDD1 "Cele\cdd-1, Cele\cdd-2" - "Mmus\Cda, Mmus\Gm15114, Mmus\Maged2, Mmus\Maged1, Mmus\Tro" "Hsap\MAGED2, Hsap\CDA, Hsap\MAGED4B, Hsap\MAGED4, Hsap\MAGED1, Hsap\TRO" viable DRSC03085 K -0.227651764 -0.449098085 1.438443853 0.174876159 0.90255534 1.700501246 FBgn0028202 l(3)S018405 lethal (3) S018405 http://flybase.org/reports/FBgn0028202 gene - - - "0184/05, l(3)S018405" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of prepupal stage,some die during prepupal stage" FBgn0000380 cs creased http://flybase.org/reports/FBgn0000380 - gene - - - cs - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile,visible,recessive" "wing,1st posterior cell" FBgn0037656 CG11986 - http://flybase.org/reports/FBgn0037656 protein_coding_gene - - - CG11986 IPR003738:SOS response associated peptidase (SRAP) CG11986 27-Aug-18 DroID_v2018_08 Drer\hmces Scer\YMR114C - Xtro\hmces Mmus\Hmces Hsap\HMCES "viable,fertile" FBgn0022787 Hel89B Helicase 89B http://flybase.org/reports/FBgn0022787 - protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000330 ATP-dependent DNA helicase activity ; GO:0004003 | inferred from sequence or structural similarity with SGD:S000006003 defense response to bacterium ; GO:0042742 | inferred from mutant phenotype Toll signaling pathway ; GO:0008063 | inferred from mutant phenotype positive regulation of antibacterial peptide biosynthetic process ; GO:0006963 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity with SGD:S000006003 antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype innate immune response ; GO:0045087 | inferred from mutant phenotype - "BTAF1, 89B, CG4261, Hel89B, Helicase89B, Mot1, HEL89B" "IPR000330:SNF2-related, N-terminal domain, IPR001650:Helicase, C-terminal, IPR011989:Armadillo-like helical, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR016024:Armadillo-type fold, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR022707:Domain of unknown function DUF3535" CG4261 27-Aug-18 DroID_v2018_08 Drer\btaf1 Scer\MOT1 Cele\btf-1 Xtro\btaf1 Mmus\Btaf1 Hsap\BTAF1 embryonic stage -- adult stage ", embryonic stage | stage >=12 , embryonic stage | early " " unfertilized egg

, longitudinal connective

,

ubiquitous , embryonic brain

, ventral nerve cord

" "visible,recessive,male sterile,partially lethal - majority die,viable" "abdominal sternite 6,male" FBgn0035318 CG9018 - http://flybase.org/reports/FBgn0035318 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG9018, FBgn0035318" "IPR006569:CID domain, IPR006903:RNA polymerase II-binding domain, IPR008942:ENTH/VHS, IPR032337:Cell-cycle alteration and expression-elevated protein in tumour" CG9018 27-Aug-18 DroID_v2018_08 "Drer\slc30a8, Drer\rprd2b, Drer\rprd1b, Drer\rprd2a" Scer\RTT103 "Cele\cids-2, Cele\cids-1" "Xtro\rprd2, Xtro\rprd1a, Xtro\rprd1b" "Mmus\Rprd1a, Mmus\Rprd1b, Mmus\Rprd2" "Hsap\RPRD1B, Hsap\RPRD2, Hsap\RPRD1A" "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0051619 nolo no long nerve cord http://flybase.org/reports/FBgn0051619 protein_coding_gene metallopeptidase activity ; GO:0008237 | inferred from electronic annotation with InterPro:IPR013273 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR013273 ventral cord development ; GO:0007419 | inferred from mutant phenotype proteinaceous extracellular matrix ; GO:0005578 | inferred from electronic annotation with InterPro:IPR013273 "CG31619, CG2131, CT6940, CG2122, CG13236, nolo" "IPR000884:Thrombospondin type-1 (TSP1) repeat, IPR003598:Immunoglobulin subtype 2, IPR007110:Immunoglobulin-like domain, IPR010909:PLAC, IPR013273:Peptidase M12B, ADAM-TS, IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set, IPR003599:Immunoglobulin subtype" CG31619 27-Aug-18 DroID_v2018_08 "Drer\LOC100002059, Drer\adamtsl2, Drer\adamts18, Drer\adamts8a, Drer\adamts2, Drer\adamtsl5, Drer\adamts6, Drer\adamts7, Drer\LOC568792, Drer\adamts15a, Drer\adamts1, Drer\adamts12, Drer\adamts13, Drer\adamtsl3, Drer\thsd7bb" - Cele\madd-4 "Xtro\thsd7b, Xtro\adamts20, Xtro\adamts6, Xtro\adamtsl3, Xtro\adamts9, Xtro\adamts7, Xtro\adamts15, Xtro\adamts16, Xtro\adamts18, Xtro\adamts12" "Mmus\Adamts6, Mmus\Adamts14, Mmus\Adamts12, Mmus\Adamtsl1, Mmus\Thsd7a, Mmus\Adamts4, Mmus\Adamts13, Mmus\Adamtsl3, Mmus\Adamts20, Mmus\Adamts10, Mmus\Adamts8, Mmus\Sspo, Mmus\Adamts7, Mmus\Adamts19, Mmus\Adamts18, Mmus\Thsd4, Mmus\Adamts15, Mmus\Adamtsl5, Mmus\Adamts9, Mmus\Adamts1, Mmus\Adamts16, Mmus\Adamtsl4" "Hsap\ADAMTSL1, Hsap\ADAMTS20, Hsap\ADAMTS15, Hsap\ADAMTS4, Hsap\ADAMTS6, Hsap\THSD4, Hsap\ADAMTS16, Hsap\ADAMTS19, Hsap\ADAMTS1, Hsap\ADAMTSL5, Hsap\ADAMTS14, Hsap\ADAMTS9, Hsap\ADAMTS10, Hsap\ADAMTS7, Hsap\ADAMTS8, Hsap\ADAMTSL4, Hsap\ADAMTS18, Hsap\ADAMTS13, Hsap\ADAMTS12, Hsap\ADAMTS17, Hsap\THSD7B, Hsap\ADAMTSL3" "visible,partially lethal - majority die,some die during pupal stage,lethal" mesothoracic tergum FBgn0267309 lncRNA:CR45745 - http://flybase.org/reports/FBgn0267309 non_protein_coding_gene - - - CR45745 - CR45745 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033997 Ir51a Ionotropic receptor 51a http://flybase.org/reports/FBgn0033997 pseudogene_attribute - - - "CG12953, DmelIR51a, CR12953, Ir51a, IR51a" - CR12953 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039015 Takl2 Tak1-like 2 http://flybase.org/reports/FBgn0039015 protein_coding_gene "MAP kinase kinase kinase activity ; GO:0004709 | inferred from electronic annotation with InterPro:IPR017421 magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR017421 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN001147562 protein kinase activity ; GO:0004672 | non-traceable author statement signal transducer activity ; GO:0004871 | inferred from biological aspect of ancestor with PANTHER:PTN000584058" protein phosphorylation ; GO:0006468 | inferred from biological aspect of ancestor with PANTHER:PTN000584058 protein phosphorylation ; GO:0006468 | non-traceable author statement intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN000584058 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001147562 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with Tak1 "CG4803, TAK, Takl2, takl2" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR017421:Mitogen-activated protein (MAP) kinase kinase kinase 7" CG4803 27-Aug-18 DroID_v2018_08 "Drer\ripk2, Drer\map3k9, Drer\map3k10, Drer\mos, Drer\ripk4, Drer\map3k7, Drer\ripk3, Drer\si:ch211-120p12.3, Drer\ripk1l, Drer\pbk, Drer\LOC405768, Drer\lrrk2, Drer\dstyk, Drer\zak" - "Cele\Y105C5A.24, Cele\mom-4" "Xtro\dstyk, Xtro\lrrk1, Xtro\map3k7, Xtro\zak, Xtro\pbk, Xtro\map3k9, Xtro\mlkl, Xtro\map3k10, Xtro\lrrk2, Xtro\LOC100490493, Xtro\ankk1, Xtro\ripk1, Xtro\ripk4" "Mmus\Map3k7, Mmus\Lrrk1, Mmus\Lrrk2, Mmus\Ripk4, Mmus\Pbk, Mmus\BC021891, Mmus\Dstyk, Mmus\Map3k11, Mmus\Map3k10, Mmus\Map3k9, Mmus\Ripk1, Mmus\Mos, Mmus\Zak, Mmus\Mlkl, Mmus\Ripk3, Mmus\Ripk2" "Hsap\IKBKB, Hsap\LRRK2, Hsap\MAP3K7, Hsap\MOS, Hsap\MLKL, Hsap\RIPK1, Hsap\MAP3K9, Hsap\MAP3K11, Hsap\PBK, Hsap\MAP3K21, Hsap\MAP3K10, Hsap\RIPK4, Hsap\DSTYK, Hsap\LRRK1, Hsap\RIPK2, Hsap\MAP3K20, Hsap\RIPK3" "viable,fertile" DRSC15650 K -0.317109345 0.089296187 -0.159757247 -0.068964564 0.459173196 -1.558132663 FBgn0027985 l(3)S132703 lethal (3) S132703 http://flybase.org/reports/FBgn0027985 gene - - - "1327/03, l(3)S132703" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0004778 Ccp84Af Ccp84Af http://flybase.org/reports/FBgn0004778 - protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model neurogenesis ; GO:0022008 | inferred from mutant phenotype extracellular matrix ; GO:0031012 | inferred from sequence model "cc3, CG1331, BG:DS00004.6, Ccp84Af, Ccp, DmelCcp84Af" IPR000618:Insect cuticle protein CG1331 27-Aug-18 DroID_v2018_08 - - Cele\fbxb-38 - - - "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" ganglion mother cell DRSC12591 I -0.79306758 -1.600176981 -1.23938521 0.336325075 0.1576713 0.231526345 FBgn0044125 E(rst)B37 E(rst)B37 http://flybase.org/reports/FBgn0044125 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "B37, E(rst)B37" - - 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0002787 Rpn8 Regulatory particle non-ATPase 8 http://flybase.org/reports/FBgn0002787 FBgn0022065 protein_coding_gene molecular_function ; GO:0003674 | no biological data available neurogenesis ; GO:0022008 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred by curator from GO:0005838 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from mutant phenotype "proteasome regulatory particle ; GO:0005838 | inferred from sequence or structural similarity with HGNC:9565 inferred from direct assay dendrite ; GO:0030425 | inferred from mutant phenotype proteasome complex ; GO:0000502 | inferred from direct assay proteasome regulatory particle, lid subcomplex ; GO:0008541 | inferred from sequence or structural similarity with SGD:S000005787 proteasome regulatory particle ; GO:0005838 | inferred from direct assay" "RPN8, CG3416, p39B, PRSC_DROME, l(2)k08003, Rpn8, Mov34, S12, P26270, PSMD7" "IPR024969:Rpn11/EIF3F, C-terminal, IPR000555:JAB1/MPN/MOV34 metalloenzyme domain, IPR033858:26S Proteasome non-ATPase regulatory subunit 7/8" CG3416 27-Aug-18 DroID_v2018_08 Drer\psmd7 Scer\RPN8 Cele\rpn-8 Xtro\psmd7 Mmus\Psmd7 Hsap\PSMD7 adult stage "lethal,recessive,visible,lethal - all die before end of pupal stage,some die during pupal stage,neuroanatomy defective,somatic clone,decreased cell number" "embryonic/larval hemocyte | third instar larval stage,wing,embryonic/larval neuroblast,ganglion mother cell,dendritic arborizing neuron,mushroom body gamma-lobe,somatic clone,neuroblast,adult mushroom body" DRSC04624 IEK -4.600104022 -3.331259077 -6.09037063 -2.616607701 1.433271406 -1.774792707 FBgn0265841 lncRNA:CR44630 - http://flybase.org/reports/FBgn0265841 non_protein_coding_gene - - - CR44630 - CR44630 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085822 CR41613 - http://flybase.org/reports/FBgn0085822 rRNA_gene - - - CR41613 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0029133 REG REG http://flybase.org/reports/FBgn0029133 protein_coding_gene endopeptidase activator activity ; GO:0061133 | inferred from direct assay endopeptidase inhibitor activity ; GO:0004866 | inferred from direct assay "regulation of proteasomal protein catabolic process ; GO:0061136 | inferred from direct assay regulation of G1/S transition of mitotic cell cycle ; GO:2000045 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013" "proteasome activator complex ; GO:0008537 | inferred from electronic annotation with InterPro:IPR003185, InterPro:IPR003186, InterPro:IPR009077 nucleus ; GO:0005634 | inferred from direct assay polytene chromosome puff ; GO:0005703 | inferred from direct assay cytoplasm ; GO:0005737 | colocalizes_with inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay nucleus ; GO:0005634 | colocalizes_with inferred from direct assay polytene chromosome interband ; GO:0005705 | inferred from direct assay nucleolus ; GO:0005730 | NOT inferred from direct assay proteasome complex ; GO:0000502 | inferred from biological aspect of ancestor with PANTHER:PTN000069920" "dREG, CG1591, REG, dReggamma, dREGgamma, REGgamma, DmREGgamma, dReg" "IPR003185:Proteasome activator pa28, N-terminal domain, IPR003186:Proteasome activator pa28, C-terminal domain, IPR009077:Proteasome activator pa28" CG1591 27-Aug-18 DroID_v2018_08 "Drer\psme2, Drer\psme3, Drer\psme1" - Cele\Y66D12A.9 "Xtro\psme2, Xtro\psme3, Xtro\psme1" "Mmus\Psme2, Mmus\Psme1, Mmus\Psme2b, Mmus\Psme3, Mmus\Aoc3" "Hsap\PSME1, Hsap\PSME3, Hsap\PSME2" "viable,fertile" FBgn0020265 oap ombre-a-paupieres http://flybase.org/reports/FBgn0020265 - gene - - - oap - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065338 l(2)SH1844 lethal (2) SH1844 http://flybase.org/reports/FBgn0065338 gene - - - "l(2)SH1844, l(2)SH2 1844" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0003363 sesF stress-sensitive F http://flybase.org/reports/FBgn0003363 - gene - - - sesF - - 27-Aug-18 DroID_v2018_08 - - - - - - uncoordinated FBgn0061473 34-20 34-20 http://flybase.org/reports/FBgn0061473 gene - - - 34-20 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0022381 Pt-10 Larval protein-10 http://flybase.org/reports/FBgn0022381 - gene - - - Pt-10 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265814 lncRNA:CR44603 - http://flybase.org/reports/FBgn0265814 non_protein_coding_gene - - - "lincRNA.10, CR44603" - CR44603 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0067359 l(2)NC85 lethal (2) NC85 http://flybase.org/reports/FBgn0067359 gene - - - "NC85, l(2)NC85" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0267287 lncRNA:CR45723 - http://flybase.org/reports/FBgn0267287 non_protein_coding_gene - - - CR45723 - CR45723 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030394 Cpr11A Cuticular protein 11A http://flybase.org/reports/FBgn0030394 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr11A, CG2560, L12" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG2560 27-Aug-18 DroID_v2018_08 Drer\LOC100003040 - "Cele\math-34, Cele\F44F1.4, Cele\sdz-30" - "Mmus\H2-K1, Mmus\2410137M14Rik" - viable FBgn0263413 lncRNA:CR43459 - http://flybase.org/reports/FBgn0263413 non_protein_coding_gene - - - "CR43459, pri-mir-277_mir-34" - CR43459 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085437 CG34408 - http://flybase.org/reports/FBgn0085437 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from biological aspect of ancestor with PANTHER:PTN001085081 regulation of small GTPase mediated signal transduction ; GO:0051056 | inferred from electronic annotation with InterPro:IPR000331 activation of GTPase activity ; GO:0090630 | inferred from biological aspect of ancestor with PANTHER:PTN001085081 - "CG34408, BcDNA:GH09358, CG2967, CG32689, FBpp0111587" IPR000331:Rap GTPase activating protein domain CG34408 27-Aug-18 DroID_v2018_08 Drer\ralgapb - "Cele\hgap-2, Cele\C34C6.2" Xtro\ralgapb Mmus\Ralgapb Hsap\RALGAPB FBgn0053349 ppk25 pickpocket 25 http://flybase.org/reports/FBgn0053349 protein_coding_gene sodium channel activity ; GO:0005272 | inferred from sequence or structural similarity with MGI:MGI:101782 protein binding ; GO:0005515 | inferred from physical interaction with CheB42a male courtship behavior ; GO:0008049 | inferred from mutant phenotype sodium ion transport ; GO:0006814 | inferred from sequence or structural similarity with MGI:MGI:101782 response to pheromone ; GO:0019236 | inferred from direct assay protein complex ; GO:0043234 | inferred from physical interaction with CheB42a integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with MGI:MGI:101782 "CG15242, CG33349, ppk25, llz" IPR001873:Epithelial sodium channel CG33349 27-Aug-18 DroID_v2018_08 "Drer\asic1c, Drer\asic2, Drer\asic1b, Drer\asic4a, Drer\asic1a, Drer\asic4b" - "Cele\acd-4, Cele\acd-1, Cele\acd-2, Cele\del-1, Cele\flr-1, Cele\del-8, Cele\degt-1, Cele\del-7, Cele\del-9, Cele\delm-1, Cele\delm-2, Cele\acd-5, Cele\acd-3" "Xtro\scnn1d, Xtro\scnn1g, Xtro\scnn1a, Xtro\scnn1b, Xtro\asic1, Xtro\asic5, Xtro\asic4" "Mmus\Scnn1b, Mmus\Scnn1g, Mmus\Scnn1a, Mmus\Asic3, Mmus\Asic4, Mmus\Asic5, Mmus\Asic2, Mmus\Asic1" "Hsap\ASIC4, Hsap\ASIC2, Hsap\SCNN1D, Hsap\SCNN1G, Hsap\ASIC1, Hsap\ASIC5, Hsap\ASIC3, Hsap\SCNN1B, Hsap\SCNN1A" "courtship behavior defective,male,heat sensitive,viable,lethal" FBgn0002437 l(3)L6B lethal (3) L6B http://flybase.org/reports/FBgn0002437 - gene - - - l(3)L6B - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0069983 BG02330 BG02330 http://flybase.org/reports/FBgn0069983 gene - - - BG02330 - - 27-Aug-18 DroID_v2018_08 - - - - - - stress response defective FBgn0044809 TotZ Turandot Z http://flybase.org/reports/FBgn0044809 protein_coding_gene - response to bacterium ; GO:0009617 | inferred from expression pattern cellular response to heat ; GO:0034605 | inferred from expression pattern response to UV ; GO:0009411 | inferred from direct assay response to heat ; GO:0009408 | inferred from direct assay response to oxidative stress ; GO:0006979 | inferred from direct assay cellular response to UV ; GO:0034644 | inferred from expression pattern cellular response to oxidative stress ; GO:0034599 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from sequence or structural similarity with TotA extracellular region ; GO:0005576 | inferred from sequence model "tot, CG31507, TotZ, Totz" IPR010825:Stress-inducible humoral factor Turandot CG31507 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0028974 xmas-2 xmas-2 http://flybase.org/reports/FBgn0028974 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VYX1 positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype poly(A)+ mRNA export from nucleus ; GO:0016973 | inferred from mutant phenotype mRNA export from nucleus ; GO:0006406 | inferred from direct assay nuclear pore ; GO:0005643 | inferred from direct assay transcription export complex 2 ; GO:0070390 | inferred from direct assay nuclear periphery ; GO:0034399 | inferred from direct assay "CG8919, CG32562, xmas-2, Xmas-2" "IPR000504:RNA recognition motif domain, IPR005062:SAC3/GANP/THP3, IPR034366:Protein xmas-2, RNA recognition motif" CG32562 27-Aug-18 DroID_v2018_08 "Drer\mcm3ap, Drer\si:zfos-452g4.1" Scer\SAC3 "Cele\tag-115, Cele\F20D12.2" Xtro\mcm3ap "Mmus\Mcm3ap, Mmus\Sac3d1" "Hsap\SAC3D1, Hsap\MCM3AP" "viable,visible" trichogen cell FBgn0000931 fs(2)A1 female sterile (2) A1 http://flybase.org/reports/FBgn0000931 - gene - - - fs(2)A1 - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive" female reproductive system FBgn0285991 hpRNA:CR18854 - http://flybase.org/reports/FBgn0042174 pseudogene_attribute RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR004088 oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR005123 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005123 - "CG13122, CG18854, CR18854" "IPR004088:K Homology domain, type 1, IPR005123:Oxoglutarate/iron-dependent dioxygenase" CR18854 27-Aug-18 DroID_v2018_08 - - - - - - embryonic/larval hemocyte | third instar larval stage DRSC02702 IE 1.646486754 1.234347995 -1.518121469 -0.008514232 1.11953391 -1.131198916 FBgn0030435 CG4645 - http://flybase.org/reports/FBgn0030435 protein_coding_gene Rab GTPase binding ; GO:0017137 | inferred from biological aspect of ancestor with PANTHER:PTN000302438 - membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR006977 Golgi apparatus ; GO:0005794 | inferred from biological aspect of ancestor with PANTHER:PTN000302438 CG4645 IPR006977:Yip1 domain CG4645 27-Aug-18 DroID_v2018_08 "Drer\yipf2, Drer\yipf1" Scer\YIP5 Cele\Y25C1A.7 "Xtro\yipf2, Xtro\yipf1" "Mmus\Yipf2, Mmus\Yipf1" "Hsap\YIPF1, Hsap\YIPF2" "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0052829 CG32829 - http://flybase.org/reports/FBgn0052829 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32829 IPR031959:Protein of unknown function DUF4779 CG32829 27-Aug-18 DroID_v2018_08 - - "Cele\C41G7.6, Cele\E03H12.5" - - - viable DRSC22805 IE 3.24409376 1.07349094 5.831226194 1.028555556 -0.334364748 1.193639713 FBgn0011858 tRNA:Phe-GAA-1-8 transfer RNA:Phenylalanine-GAA 1-8 http://flybase.org/reports/FBgn0011858 "FBgn0011856, FBgn0051586, FBgn0060232" tRNA_gene UUC codon-amino acid adaptor activity ; GO:0033402 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033402 cytosol ; GO:0005829 | inferred by curator from GO:0033402 "tRNA-Phe-2, phe-tRNA-2, AE002708.trna6-PheGAA, tRNA:F:GAA:AE002708-b, CR31586, tRNA:phe2:89BC, chr3R.trna12-PheGAA, tRNA-Phe-GAA-1-8, tRNA:Phe-GAA-1-8, tRNA:F2:89BC, UUC" - CR31586 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0041584 whsc1 whsc1 http://flybase.org/reports/FBgn0041584 gene - - - "Dm_whsc1, whsc1" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260017 troya troya http://flybase.org/reports/FBgn0260017 gene - - - troya - - 27-Aug-18 DroID_v2018_08 - - - - - - chorion | germline clone FBgn0267059 lncRNA:CR45503 - http://flybase.org/reports/FBgn0267059 non_protein_coding_gene - - - "CR45503, Dm_X:95517" - CR45503 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0261998 CG42816 - http://flybase.org/reports/FBgn0261998 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from biological aspect of ancestor with PANTHER:PTN000442469 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from sequence or structural similarity with UniProtKB:O94911" lipid transport ; GO:0006869 | inferred from biological aspect of ancestor with PANTHER:PTN000442469 transport ; GO:0006810 | inferred from sequence or structural similarity with UniProtKB:O94911 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000442469 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with UniProtKB:Q9BZC7 "CG42816, CG32186, CG5587, CG5944" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR026082:ABC transporter A, ABCA" CG42816 27-Aug-18 DroID_v2018_08 "Drer\abca5, Drer\abca1b, Drer\abch1, Drer\abca3b, Drer\abca2, Drer\abca12, Drer\abca1a" - "Cele\abt-1, Cele\abt-2, Cele\ced-7, Cele\abt-5, Cele\abt-4" "Xtro\abca8, Xtro\abca10, Xtro\abca9, Xtro\abca2, Xtro\abca4, Xtro\abca1, Xtro\abca3" "Mmus\Abca14, Mmus\Abca13, Mmus\Abca9, Mmus\Abca1, Mmus\Abca7, Mmus\Abca2, Mmus\Abca8b, Mmus\Abca17, Mmus\Abca15, Mmus\Abca8a, Mmus\Abca6, Mmus\Abca3, Mmus\Abca16, Mmus\Abca5, Mmus\Abca4, Mmus\Abca12" "Hsap\ABCA12, Hsap\ABCA8, Hsap\ABCA10, Hsap\ABCA3, Hsap\ABCA13, Hsap\ABCA6, Hsap\ABCA4, Hsap\ABCA2, Hsap\ABCA5, Hsap\ABCA9, Hsap\ABCA1, Hsap\ABCA7" FBgn0035815 Snmp2 Sensory neuron membrane protein 2 http://flybase.org/reports/FBgn0035815 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002159 "148358_at, CG16832, Snmp2, SNMP2, CG7422" IPR002159:CD36 family CG7422 27-Aug-18 DroID_v2018_08 "Drer\scarb1, Drer\cd36, Drer\scarb2, Drer\LOC564077" - "Cele\scav-6, Cele\scav-4, Cele\scav-3, Cele\scav-2, Cele\scav-1, Cele\scav-5" "Xtro\cd36, Xtro\scarb2, Xtro\scarb1" "Mmus\Scarb1, Mmus\Scarb2, Mmus\Cd36" "Hsap\SCARB1, Hsap\CD36, Hsap\SCARB2" viable FBgn0046633 anon-38E.24 anon-38E.24 http://flybase.org/reports/FBgn0046633 gene - - - "38E.24, anon-38E.24" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005470 l(1)ts455b lethal (1) ts455b http://flybase.org/reports/FBgn0005470 - gene - - - l(1)ts455b - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030202 CG12640 - http://flybase.org/reports/FBgn0030202 protein_coding_gene - - - CG12640 - CG12640 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0004487 l(1)air14 lethal aberrant immune response 14 http://flybase.org/reports/FBgn0004487 - gene - - - l(1)air14 - - 27-Aug-18 DroID_v2018_08 - - - - - - "melanotic mass phenotype,lethal - all die before end of larval stage,recessive,some die during larval stage" "embryonic/larval brain,melanotic mass,embryonic/larval lymph gland" FBgn0260033 siren7 siren 7 http://flybase.org/reports/FBgn0260033 gene - - - siren7 - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,somatic clone" "wing,somatic clone" FBgn0032863 Cdc23 Cell division cycle 23 http://flybase.org/reports/FBgn0032863 protein_coding_gene ubiquitin protein ligase activity ; GO:0061630 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype endomitotic cell cycle ; GO:0007113 | inferred from mutant phenotype positive regulation of mitotic metaphase/anaphase transition ; GO:0045842 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype anaphase-promoting complex ; GO:0005680 | inferred from physical interaction with APC7 "CG2508, 38C.54, CG2508-PA, cdc23, Apc8, Cdc23, APC8, CDC23" "IPR007192:Cdc23, IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat" CG2508 27-Aug-18 DroID_v2018_08 Drer\cdc23 Scer\CDC23 Cele\mat-3 Xtro\cdc23 Mmus\Cdc23 Hsap\CDC23 "lethal,mitotic cell cycle defective,increased cell death,endomitotic cell cycle defective,somatic clone,neuroanatomy defective,viable,fertile" "melanotic mass | third instar larval stage,nucleus | somatic clone,embryonic/larval neuroblast,ganglion mother cell" DRSC02708 I 2.692322675 1.116932439 0.602494993 -0.636278521 0.082502712 -0.581288585 FBgn0037101 CG7634 - http://flybase.org/reports/FBgn0037101 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG7634 IPR011990:Tetratricopeptide-like helical domain CG7634 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0014292 l(3)64Bc lethal (3) 64Bc http://flybase.org/reports/FBgn0014292 - gene - - - l(3)64Bc - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259916 CG42445 - http://flybase.org/reports/FBgn0259916 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42445, CG7498" - CG42445 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262334 mir-992 mir-992 stem loop http://flybase.org/reports/FBgn0262334 miRNA_gene - - - "dme-mir-992, mir-992, CR43041, miR-992" - CR43041 27-Aug-18 DroID_v2018_08 - - - - - - "visible,lethal,lethal - all die before end of P-stage,some die during pharate adult stage" "eye,wing" FBgn0015406 l(1)12Ba lethal (1) 12Ba http://flybase.org/reports/FBgn0015406 - gene - - - l(1)12Ba - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0037150 CG7133 - http://flybase.org/reports/FBgn0037150 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN001180323 CG7133 IPR001623:DnaJ domain CG7133 27-Aug-18 DroID_v2018_08 "Drer\dnajc30b, Drer\dnajc5gb, Drer\dnajc5ab, Drer\dnaja2l, Drer\dnajc30, Drer\dnaja1, Drer\dnajc5ga, Drer\dnajc5aa, Drer\dnaja2, Drer\dnajc5b" "Scer\XDJ1, Scer\YDJ1, Scer\ERJ5, Scer\JJJ2, Scer\CWC23, Scer\HLJ1, Scer\APJ1, Scer\SCJ1" "Cele\dnj-26, Cele\dnj-14, Cele\dnj-4" "Xtro\dnaja4.1, Xtro\dnaja2, Xtro\dnaja1, Xtro\dnaja4.2, Xtro\dnajc5g" "Mmus\Dnaja4, Mmus\Dnajc5g, Mmus\Dnajc5, Mmus\Dnajc30, Mmus\Dnaja1, Mmus\Dnajc5b, Mmus\Dnaja2" "Hsap\DNAJA2, Hsap\DNAJA4, Hsap\DNAJC5, Hsap\DNAJC30, Hsap\DNAJA1, Hsap\DNAJC5G, Hsap\DNAJC5B" viable FBgn0265216 fs(2)Z2-2984 - http://flybase.org/reports/FBgn0265216 gene - - - fs(2)Z2-2984 - - 27-Aug-18 DroID_v2018_08 - - - - - - female sterile FBgn0014988 l(2)46Dd lethal (2) 46Dd http://flybase.org/reports/FBgn0014988 - gene - - - "X, l(2)46Dd" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0260243 E(var)3-9 Enhancer of variegation 3-9 http://flybase.org/reports/FBgn0260243 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 chromatin maintenance ; GO:0070827 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 "E(var)3-9, CG11971, E-var(3)9, anon1E9, Anon1E9, 1E9, anon-EST:fe1E9" "IPR012934:Zinc finger, AD-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG11971 27-Aug-18 DroID_v2018_08 "Drer\znf1078, Drer\si:dkey-208k4.2, Drer\znf1007" Scer\PZF1 - Xtro\znf684 "Mmus\Zfp974, Mmus\Zfp658, Mmus\Zfx, Mmus\Ikzf5, Mmus\Zfp623, Mmus\Zbtb25" "Hsap\CTCFL, Hsap\ZNF605, Hsap\ZBTB24, Hsap\ZFP37, Hsap\ZNF37A, Hsap\IKZF5, Hsap\ZFP92, Hsap\ZBTB25" FBgn0267011 lncRNA:CR45455 - http://flybase.org/reports/FBgn0267011 non_protein_coding_gene - - - CR45455 - CR45455 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265658 lncRNA:CR44465 - http://flybase.org/reports/FBgn0265658 non_protein_coding_gene - - - CR44465 - CR44465 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030745 CG4239 - http://flybase.org/reports/FBgn0030745 protein_coding_gene calcium-activated potassium channel activity ; GO:0015269 | inferred from biological aspect of ancestor with PANTHER:PTN000278842 monovalent inorganic cation transport ; GO:0015672 | inferred from electronic annotation with InterPro:IPR007866 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR007866 CG4239 IPR007866:TRIC channel CG4239 27-Aug-18 DroID_v2018_08 "Drer\tmem38b, Drer\tmem38a" - "Cele\Y57A10A.28, Cele\Y57A10A.10" "Xtro\tmem38a, Xtro\tmem38b" "Mmus\Tmem38b, Mmus\Tmem38a" "Hsap\TMEM38A, Hsap\TMEM38B" "lethal,partially lethal - majority die" FBgn0024723 Su(var)47E48A Su(var)47E48A http://flybase.org/reports/FBgn0024723 - gene - - - Su(var)47E48A - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0250911 CG42245 - http://flybase.org/reports/FBgn0250911 protein_coding_gene - - - CG42245 IPR027911:Domain of unknown function DUF4604 CG42245 27-Aug-18 DroID_v2018_08 Drer\zgc:77056 - Cele\T25G3.1 Xtro\kiaa1143 Mmus\1110059G10Rik Hsap\KIAA1143 FBgn0005242 l(3)R102 lethal of Roberts 102 http://flybase.org/reports/FBgn0005242 - gene - - - "l(3)102, l(3)R102" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,polyphasic,recessive" FBgn0083040 snoRNA:Psi18S-1854c snoRNA:Psi18S-1854c http://flybase.org/reports/FBgn0083040 snoRNA_gene - - - "snoRNA:Psi18S-1854c, Psi18S-1854c, psi18S-1854c, CR34598, chrX:16979184..16979324" - CR34598 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259326 EP-319 - http://flybase.org/reports/FBgn0259326 gene - - - EP-319 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing hair,wing margin,chaeta" FBgn0260806 EP3-934 - http://flybase.org/reports/FBgn0260806 gene - - - EP3-934 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0010094 Su(w[a4]) Suppressor of white-apricot 4 http://flybase.org/reports/FBgn0010094 - gene - - - Su(w[a4]) - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262838 CG43202 - http://flybase.org/reports/FBgn0262838 protein_coding_gene - - - "CG43202, DMG8-chr2R.26.014, CG42737, chr2R.1731" - CG43202 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0011183 l(1)294-22 lethal (1) 294-22 http://flybase.org/reports/FBgn0011183 FBgn0010200 gene - - - "294-22, l(1)294-22" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0032090 CG9582 - http://flybase.org/reports/FBgn0032090 protein_coding_gene dicarboxylic acid transmembrane transporter activity ; GO:0005310 | inferred from biological aspect of ancestor with PANTHER:PTN001183940 mitochondrial transport ; GO:0006839 | inferred from biological aspect of ancestor with PANTHER:PTN001183940 dicarboxylic acid transport ; GO:0006835 | inferred from biological aspect of ancestor with PANTHER:PTN001183940 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN001183940 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 CG9582 "IPR018108:Mitochondrial substrate/solute carrier, IPR023395:Mitochondrial carrier domain" CG9582 27-Aug-18 DroID_v2018_08 Drer\slc25a21 "Scer\ODC1, Scer\ODC2" Cele\slc-25A21 Xtro\slc25a21 Mmus\Slc25a21 Hsap\SLC25A21 "viable,fertile" FBgn0051699 CG31699 - http://flybase.org/reports/FBgn0051699 protein_coding_gene - - - CG31699 - - 27-Aug-18 DroID_v2018_08 - - - - - - DRSC22062 E -0.490699578 0.050299163 -1.833773621 -0.143108806 0.696804445 -0.211590067 FBgn0017627 Eig45Aa Eig45Aa http://flybase.org/reports/FBgn0017627 - gene - - - "Eig45-1, Eig45Aa" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0021768 nudC nudC http://flybase.org/reports/FBgn0021768 FBgn0036664 protein_coding_gene unfolded protein binding ; GO:0051082 | inferred from biological aspect of ancestor with PANTHER:PTN000270240 positive regulation of dendrite morphogenesis ; GO:0050775 | inferred from genetic interaction with dar1 nucleus localization ; GO:0051647 | inferred from mutant phenotype protein folding ; GO:0006457 | inferred from biological aspect of ancestor with PANTHER:PTN000270240 nuclear migration ; GO:0007097 | inferred from sequence or structural similarity with UniProtKB:P17624 microtubule associated complex ; GO:0005875 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "Q9VVA6, CG9710, DnudC, NUDC, nudC, NudC" "IPR025934:NudC N-terminal domain, IPR007052:CS domain, IPR008978:HSP20-like chaperone" CG9710 27-Aug-18 DroID_v2018_08 "Drer\nudcd3, Drer\nudcd2, Drer\nudc" - Cele\nud-1 "Xtro\nudcd2, Xtro\nudcd3, Xtro\nudc" "Mmus\Nudcd3, Mmus\Nudc, Mmus\Nudcd2" "Hsap\NUDCD3, Hsap\NUDCD2, Hsap\NUDC" "viable,fertile" FBgn0002448 l(3)SG1 lethal (3) SG1 http://flybase.org/reports/FBgn0002448 FBgn0004706 gene - - - "l(3)dsl-4, l(3)g60L, l(3)dsl4, l(3)A4, l(3)SG1" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" imaginal disc FBgn0035526 CG1316 - http://flybase.org/reports/FBgn0035526 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity - - "cg1316, CG1316" "IPR000504:RNA recognition motif domain, IPR034206:RBM45, RNA recognition motif 2, IPR034203:RBM45, RNA recognition motif 1, IPR034208:RBM45, RNA recognition motif 4, IPR034207:RBM45, RNA recognition motif 3" CG1316 27-Aug-18 DroID_v2018_08 Drer\rbm45 - - Xtro\rbm45 Mmus\Rbm45 Hsap\RBM45 "partially lethal - majority die,some die during pupal stage" FBgn0033401 CG1968 - http://flybase.org/reports/FBgn0033401 protein_coding_gene molecular_function ; GO:0003674 | no biological data available intra-Golgi vesicle-mediated transport ; GO:0006891 | inferred from sequence or structural similarity with SGD:S000004986 intra-Golgi vesicle-mediated transport ; GO:0006891 | inferred from biological aspect of ancestor with PANTHER:PTN000487537 Golgi transport complex ; GO:0017119 | inferred from direct assay "Cog6, CG1968" IPR010490:Conserved oligomeric Golgi complex subunit 6 CG1968 27-Aug-18 DroID_v2018_08 Drer\cog6 Scer\COG6 Cele\cogc-6 Xtro\cog6 Mmus\Cog6 Hsap\COG6 viable FBgn0045041 l(1)G0302 lethal (1) G0302 http://flybase.org/reports/FBgn0045041 gene - - - l(1)G0302 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0010809 l(3)03675 lethal (3) 03675 http://flybase.org/reports/FBgn0010809 - gene - - - l(3)03675 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0250828 CR41437 - http://flybase.org/reports/FBgn0250828 non_protein_coding_gene - - - "CR41437, anon-EST:Posey146" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266827 lncRNA:CR45289 - http://flybase.org/reports/FBgn0266827 non_protein_coding_gene - - - CR45289 - CR45289 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005236 l(3)R45 lethal of Roberts 45 http://flybase.org/reports/FBgn0005236 - gene - - - "l(3)B45, l(3)R45" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,polyphasic,recessive" FBgn0034663 CG4363 - http://flybase.org/reports/FBgn0034663 protein_coding_gene - - - "CT14230, BcDNA:LP06375, CG4363" IPR008472:Domain of unknown function DUF753 CG4363 27-Aug-18 DroID_v2018_08 - - "Cele\D1081.6, Cele\C54D10.13, Cele\ZK757.10, Cele\F55B11.4" - "Mmus\Ly6d, Mmus\Slurp2, Mmus\Lynx1, Mmus\2010109I03Rik" "Hsap\LYNX1, Hsap\LY6D" viable FBgn0061052 l(3)S023204a lethal (3) S023204a http://flybase.org/reports/FBgn0061052 gene - - - "0232/04, l(3)S023204a" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0250903 lmgA lemming A http://flybase.org/reports/FBgn0250903 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin protein ligase activity ; GO:0061630 | inferred from direct assay anaphase-promoting complex-dependent catabolic process ; GO:0031145 | inferred from direct assay positive regulation of mitotic metaphase/anaphase transition ; GO:0045842 | inferred from mutant phenotype protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with HGNC:14452 ubiquitin ligase complex ; GO:0000151 | inferred from direct assay anaphase-promoting complex ; GO:0005680 | inferred from direct assay "CG34440, lmgA, lmg, ORF1, CG18042, l(2)03424, Dromel_CG18042_FBtr0079695_lmg_uORF, Apc11, APC11, Img, LMG" "IPR024991:Anaphase-promoting complex subunit 11, IPR001841:Zinc finger, RING-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG34440 27-Aug-18 DroID_v2018_08 Drer\anapc11 Scer\APC11 Cele\apc-11 Xtro\anapc11 Mmus\Anapc11 Hsap\ANAPC11 "lethal,recessive,neuroanatomy defective,somatic clone,increased cell death,mitotic cell cycle defective,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of prepupal stage,some die during prepupal stage,viable,fertile" "eye,histoblast,neuroblast,somatic clone,embryonic/larval brain,wing disc,intersegmental nerve,anterior fascicle & synapse" FBgn0260495 l(3)2727 - http://flybase.org/reports/FBgn0260495 gene - dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype - l(3)2727 - - 27-Aug-18 DroID_v2018_08 - - - - - - neuroanatomy defective "dendritic arborizing neuron,dendrite" FBgn0002259 l(3)68Fd lethal (3) 68Fd http://flybase.org/reports/FBgn0002259 - gene - - - "rsg21, l(3)rsg21, l(3)68Fd" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0027778 anon-1Ab anon-1Ab http://flybase.org/reports/FBgn0027778 - gene - - - "1A, anon-1Ab" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0027795 CG14785 - http://flybase.org/reports/FBgn0027795 - protein_coding_gene - - - "EG:BACN32G11.2, CG14785" "IPR011705:BTB/Kelch-associated, IPR031750:Domain of unknown function DUF4734" CG14785 27-Aug-18 DroID_v2018_08 Drer\klhl41a - Cele\kel-3 - - "Hsap\KLHL9, Hsap\KLHL31" viable FBgn0011951 tRNA:Arg-TCG-3-4 transfer RNA:Arginine-TCG 3-4 http://flybase.org/reports/FBgn0011951 "FBgn0011947, FBgn0052617, FBgn0060079" tRNA_gene CGA codon-amino acid adaptor activity ; GO:0033431 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033431 cytosol ; GO:0005829 | inferred by curator from GO:0033431 "tRNA-Arg, tRNA[arg], AE002593.trna7-ArgTCG, tRNA:R1, tRNA:arg1, tRNA:R:TCG:AE002593-e, CR32617, tRNA:arg12Ed, chrX.trna11-ArgTCG, tRNA-Arg-TCG-3-4, tRNA:Arg-TCG-3-4, tRNA:R:12Ed, CGA" - CR32617 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060343 l(3)S143814 lethal (3) S143814 http://flybase.org/reports/FBgn0060343 gene - - - "1438/14, l(3)S143814" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0060527 l(3)S101715b lethal (3) S101715b http://flybase.org/reports/FBgn0060527 gene - - - "1017/15, l(3)S101715b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0005035 e(S)r "enhancer of Star, recessive" http://flybase.org/reports/FBgn0005035 - gene - - - "S-i, e(S)r, e(S)" - - 27-Aug-18 DroID_v2018_08 - - - - - - wild-type FBgn0005157 l(2)G129 lethal (2) G129 http://flybase.org/reports/FBgn0005157 - gene - - - l(2)G129 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0022726 milo milo http://flybase.org/reports/FBgn0022726 - gene molecular_function ; GO:0003674 | no biological data available growth ; GO:0040007 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available milo - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035423 eIF1 eukaryotic translation initiation factor 1 http://flybase.org/reports/FBgn0035423 protein_coding_gene translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity with SGD:S000005188 cellular response to hypoxia ; GO:0071456 | inferred from mutant phenotype formation of translation preinitiation complex ; GO:0001731 | inferred from sequence or structural similarity with SGD:S000005188 eukaryotic 43S preinitiation complex ; GO:0016282 | inferred from sequence or structural similarity with SGD:S000005188 multi-eIF complex ; GO:0043614 | inferred from sequence or structural similarity with SGD:S000005188 "anon-EST:Posey272, BcDNA:RE14985, CG17737, dEIF1, eIF1" "IPR001950:SUI1 domain, IPR005874:Eukaryotic translation initiation factor SUI1" CG17737 27-Aug-18 DroID_v2018_08 "Drer\eif1b, Drer\zgc:56676" Scer\SUI1 Cele\eif-1 "Xtro\eif1b, Xtro\eif1" "Mmus\Eif1b, Mmus\Eif1" "Hsap\EIF1B, Hsap\EIF1" viable FBgn0000708 fltN flight defective N http://flybase.org/reports/FBgn0000708 - gene - - - fltN - - 27-Aug-18 DroID_v2018_08 - - - - - - flight defective FBgn0027969 l(3)S144405 lethal (3) S144405 http://flybase.org/reports/FBgn0027969 gene - - - "1444/05, l(3)S144405" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0010492 l(2)01482 lethal (2) 01482 http://flybase.org/reports/FBgn0010492 - gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available l(2)01482 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,partially,rescuable maternal effect,partially lethal - majority die" "embryonic/first instar larval cuticle,head,abdomen,posterior" FBgn0011380 l(3)j5B6 lethal (3) j5B6 http://flybase.org/reports/FBgn0011380 - gene - - - l(3)j5B6 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0053140 CG33140 - http://flybase.org/reports/FBgn0053140 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG11074, BcDNA:AT21895, CG33140" "IPR032707:MYCBP-associated protein, IPR013783:Immunoglobulin-like fold" CG33140 27-Aug-18 DroID_v2018_08 Drer\mycbpap - - - Mmus\Mycbpap - viable FBgn0014465 Cp7Fb Chorion protein b at 7F http://flybase.org/reports/FBgn0014465 FBgn0030044 protein_coding_gene - chorion-containing eggshell formation ; GO:0007304 | inferred from expression pattern inferred from genomic context chorion ; GO:0042600 | inferred by curator from GO:0007304 inferred from genomic context "Cp7Fb, CG15350, C, B, cp7Fb" - CG15350 27-Aug-18 DroID_v2018_08 - - - - - - " adult stage && oogenesis stage | stage S10B-13 , oogenesis stage | stage S10-12 " follicle cell

FBgn0014094 anon-3Aa anon-3Aa http://flybase.org/reports/FBgn0014094 - gene - - - anon-3Aa - - 27-Aug-18 DroID_v2018_08 - - - - - - " embryonic stage , adult stage " FBgn0264700 lncRNA:CR43969 - http://flybase.org/reports/FBgn0264700 non_protein_coding_gene - - - CR43969 - CR43969 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0052643 CG32643 - http://flybase.org/reports/FBgn0052643 protein_coding_gene - - - "NEST:bs08h10, CG32643" - CG32643 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0060335 l(3)S144608 lethal (3) S144608 http://flybase.org/reports/FBgn0060335 gene - - - "1446/08, l(3)S144608" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0023473 anon-30Fa anon-30Fa http://flybase.org/reports/FBgn0023473 - gene - - - anon-30Fa - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0061073 l(3)S016704b lethal (3) S016704b http://flybase.org/reports/FBgn0061073 gene - - - "0167/04, l(3)S016704b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0022725 p22 p22 http://flybase.org/reports/FBgn0022725 - gene - - - p22 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004801 fs(2)ltoRG3 female sterile (2) ltoRG3 http://flybase.org/reports/FBgn0004801 - gene molecular_function ; GO:0003674 | no biological data available ovarian follicle cell migration ; GO:0007297 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(2)ltoRG3 - - 27-Aug-18 DroID_v2018_08 - - - - - - female sterile FBgn0266671 Sec6 Secretory 6 http://flybase.org/reports/FBgn0266671 protein_coding_gene SNARE binding ; GO:0000149 | inferred from biological aspect of ancestor with PANTHER:PTN000480155 SNARE binding ; GO:0000149 | inferred from sequence or structural similarity with SGD:S000001330 protein localization to plasma membrane ; GO:0072659 | inferred from mutant phenotype exocytosis ; GO:0006887 | inferred from biological aspect of ancestor with PANTHER:PTN000480155 exocytosis ; GO:0006887 | inferred from mutant phenotype endocytic recycling ; GO:0032456 | inferred from mutant phenotype neurotransmitter secretion ; GO:0007269 | non-traceable author statement vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity protein localization to cell cortex ; GO:0072697 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype exocyst localization ; GO:0051601 | inferred from biological aspect of ancestor with PANTHER:PTN000480155 plasma membrane organization ; GO:0007009 | inferred from mutant phenotype synaptic vesicle targeting ; GO:0016080 | non-traceable author statement synaptic vesicle docking ; GO:0016081 | non-traceable author statement border follicle cell migration ; GO:0007298 | inferred from mutant phenotype rhabdomere membrane biogenesis ; GO:0045313 | inferred from mutant phenotype Golgi to plasma membrane protein transport ; GO:0043001 | inferred from mutant phenotype exocyst ; GO:0000145 | inferred from direct assay exocyst ; GO:0000145 | inferred from sequence or structural similarity cytoplasm ; GO:0005737 | inferred from direct assay zonula adherens ; GO:0005915 | inferred from direct assay membrane ; GO:0016020 | inferred from direct assay exocyst ; GO:0000145 | inferred from biological aspect of ancestor with PANTHER:PTN000480155 exocyst ; GO:0000145 | non-traceable author statement rhabdomere ; GO:0016028 | inferred from direct assay "sec6, Sec6, CG5341, Dsec6, sec 6, Sec6p, dsec6" IPR010326:Exocyst complex component EXOC3/Sec6 CG5341 27-Aug-18 DroID_v2018_08 "Drer\exoc3l2b, Drer\exoc3l2a, Drer\tnfaip2b, Drer\exoc3l4, Drer\exoc3l1, Drer\si:dkey-45k15.1, Drer\tnfaip2a, Drer\exoc3" Scer\SEC6 Cele\sec-6 "Xtro\exoc3, Xtro\exoc3l1, Xtro\tnfaip2" "Mmus\Exoc3l2, Mmus\Exoc3, Mmus\Tnfaip2, Mmus\Exoc3l4, Mmus\Exoc3l" "Hsap\EXOC3L4, Hsap\EXOC3L1, Hsap\TNFAIP2, Hsap\EXOC3, Hsap\EXOC3L2" DRSC06932 EK -0.322984004 -0.482431596 -2.177827747 1.107653421 -0.082435357 2.222515112 FBgn0002123 l(2)hst lethal (2) histolytic http://flybase.org/reports/FBgn0002123 - gene - - - l(2)hst - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0265471 CR44364 - http://flybase.org/reports/FBgn0265471 non_protein_coding_gene - - - CR44364 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264828 lncRNA:CR44036 - http://flybase.org/reports/FBgn0264828 non_protein_coding_gene - - - CR44036 - CR44036 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030797 CG13004 - http://flybase.org/reports/FBgn0030797 protein_coding_gene - - - CG13004 - CG13004 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible" mesothoracic tergum FBgn0005523 l(2)52Dc lethal (2) 52Dc http://flybase.org/reports/FBgn0005523 - gene - - - l(2)52Dc - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267662 lncRNA:CR46000 - http://flybase.org/reports/FBgn0267662 non_protein_coding_gene - - - CR46000 - CR46000 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0086669 snoRNA:Psi18S-841a snoRNA:Psi18S-841a http://flybase.org/reports/FBgn0086669 snoRNA_gene - - - "snoRNA:66, psi18S-841a, Dm-66, snoR66, CR33765, Psi 18S-841a(SnoR66), Psi18S-841a, snoRNA:Psi18S-841a, psi-18S-841a" - CR33765 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036235 CG6938 - http://flybase.org/reports/FBgn0036235 protein_coding_gene protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR032394 intracellular calcium activated chloride channel activity ; GO:0005229 | inferred from sequence or structural similarity with HGNC:27337 chloride transport ; GO:0006821 | inferred from sequence or structural similarity with HGNC:27337 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with HGNC:27337 CG6938 "IPR007632:Anoctamin, IPR032394:Anoctamin, dimerisation domain" CG6938 27-Aug-18 DroID_v2018_08 "Drer\ano5a, Drer\ano11, Drer\LOC562630, Drer\LOC101886340, Drer\si:dkey-83h2.5, Drer\ano8b, Drer\ano9b, Drer\LOC103910000, Drer\ano6, Drer\ano8a, Drer\LOC101886884, Drer\ano9a, Drer\ano5b, Drer\LOC563500, Drer\ano2, Drer\ano1, Drer\ano3" Scer\IST2 "Cele\anoh-1, Cele\anoh-2" "Xtro\ano3, Xtro\ano2, Xtro\ano9, Xtro\ano1, Xtro\ano5" "Mmus\Ano8, Mmus\Ano5, Mmus\Ano9, Mmus\Ano6, Mmus\Ano3, Mmus\Ano2, Mmus\Ano7, Mmus\Ano4, Mmus\Ano1" "Hsap\ANO9, Hsap\ANO1, Hsap\ANO4, Hsap\ANO5, Hsap\ANO2, Hsap\ANO8, Hsap\ANO3, Hsap\ANO7, Hsap\ANO6" viable FBgn0263595 lncRNA:CR43617 - http://flybase.org/reports/FBgn0263595 non_protein_coding_gene - - - "CR43617, Dm_3R:69251" - CR43617 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030222 CG9806 - http://flybase.org/reports/FBgn0030222 protein_coding_gene metalloaminopeptidase activity ; GO:0070006 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 peptide binding ; GO:0042277 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern peptide catabolic process ; GO:0043171 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 extracellular region ; GO:0005576 | inferred from sequence model cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 CG9806 "IPR024571:ERAP1-like C-terminal domain, IPR001930:Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR014782:Peptidase M1, membrane alanine aminopeptidase, N-terminal" CG9806 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-106j24.1, Drer\anpepb, Drer\si:ch211-198g19.1, Drer\si:ch211-276a23.5, Drer\lnpep, Drer\erap1b, Drer\erap1a, Drer\erap2, Drer\enpep, Drer\anpepa, Drer\si:ch211-149p5.1, Drer\npepps" "Scer\AAP1, Scer\TMA108, Scer\APE2" "Cele\R03G8.4, Cele\VB0395L.1, Cele\T16G12.1, Cele\R03G8.6, Cele\Y67D8C.9, Cele\AC3.5, Cele\F49B2.6, Cele\Y42A5A.1, Cele\T12E12.6, Cele\pam-1, Cele\T07F10.1, Cele\Y53F4B.20, Cele\mnp-1" "Xtro\npepps, Xtro\lnpep, Xtro\erap1, Xtro\lvrn, Xtro\anpep, Xtro\enpep" "Mmus\Npepps, Mmus\Lvrn, Mmus\Enpep, Mmus\Erap1, Mmus\Trhde, Mmus\Lnpep, Mmus\Anpep" "Hsap\LVRN, Hsap\NPEPPS, Hsap\ANPEP, Hsap\TRHDE, Hsap\ERAP2, Hsap\LNPEP, Hsap\ENPEP, Hsap\ERAP1" "viable,visible" trichogen cell FBgn0028628 ksh-19 ksh-19 http://flybase.org/reports/FBgn0028628 gene - - - ksh-19 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034329 IM1 Immune induced molecule 1 http://flybase.org/reports/FBgn0034329 protein_coding_gene - defense response ; GO:0006952 | inferred from direct assay response to bacterium ; GO:0009617 | inferred from expression pattern extracellular region ; GO:0005576 | inferred from direct assay "CG18108, DIM-1, IM2-like, DIM 1, BcDNA:RH08745, IM1" IPR013172:Immune-induced protein Dim CG18108 27-Aug-18 DroID_v2018_08 - - - - - - "viable,body color defective" mesothoracic tergum FBgn0040157 l(1)G0459 lethal (1) G0459 http://flybase.org/reports/FBgn0040157 gene - - - l(1)G0459 - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive,female sterile" FBgn0019903 anon-14Bg anon-14Bg http://flybase.org/reports/FBgn0019903 - gene - - - "ORF, anon-14Bg" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259528 B0097 - http://flybase.org/reports/FBgn0259528 gene - - - B0097 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible wing FBgn0045032 usp::Cten\Usp-1 Usp-1 http://flybase.org/reports/FBgn0045032 engineered_fusion_gene - - - usp::Cten\Usp-1 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0001066 Fs(3)Tev Female sterile (3) Tevel http://flybase.org/reports/FBgn0001066 - gene - - - "Fs(3)Tevel, Fs(3)Sz21, Fs(3)Tev" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "embryonic/first instar larval cuticle,maternal effect,embryonic head" FBgn0015569 alpha-Est10 alpha-Esterase-10 http://flybase.org/reports/FBgn0015569 FBgn0046454 protein_coding_gene - imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "Esterase-10, alpha-Ests, alphaE10, aE10, K, CG1131, anon-WO0172774.144, alpha-Est10, DmalphaE10" "IPR002018:Carboxylesterase, type B, IPR019826:Carboxylesterase type B, active site, IPR029058:Alpha/Beta hydrolase fold" CG1131 27-Aug-18 DroID_v2018_08 "Drer\nlgn4b, Drer\ces2, Drer\nlgn1, Drer\cell, Drer\nlgn3a, Drer\cel.1, Drer\si:ch211-93f2.1, Drer\nlgn3b, Drer\nlgn2a, Drer\ces3, Drer\nlgn2b, Drer\nlgn4a" - "Cele\Y71H2AM.13, Cele\T02B5.3, Cele\B0238.7, Cele\F56C11.6, Cele\F15A8.6, Cele\T28C12.5, Cele\T28C12.4, Cele\R173.3, Cele\F07C4.12, Cele\K07C11.4, Cele\K11G9.2, Cele\F13H6.3, Cele\K11G9.3, Cele\C52A10.1, Cele\T07H6.1, Cele\K11G9.1" "Xtro\cel, Xtro\LOC100494782, Xtro\ces3, Xtro\ces2, Xtro\nlgn3, Xtro\nlgn4x, Xtro\nlgn2" "Mmus\Ces1h, Mmus\Ces2c, Mmus\Ces2h, Mmus\Ces2e, Mmus\Nlgn2, Mmus\Ces2a, Mmus\Ces2f, Mmus\Nlgn1, Mmus\Ces5a, Mmus\Ces1c, Mmus\Ces1f, Mmus\Nlgn3, Mmus\Ces1e, Mmus\Ces1d, Mmus\Ces2g, Mmus\Ces2b, Mmus\Ces4a, Mmus\Ces1b, Mmus\Ces3a, Mmus\Ces3b, Mmus\Ces1g, Mmus\Cel" "Hsap\CES4A, Hsap\NLGN4Y, Hsap\CES2, Hsap\NLGN2, Hsap\CEL, Hsap\NLGN4X, Hsap\CES5A, Hsap\NLGN1, Hsap\CES3, Hsap\CES1, Hsap\NLGN3" viable FBgn0026204 milou milou http://flybase.org/reports/FBgn0026204 - gene - - - milou - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" "wing disc,wing" FBgn0036597 CG4962 - http://flybase.org/reports/FBgn0036597 protein_coding_gene - - - "CT15908, CG4962" - CG4962 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0266776 lncRNA:CR45241 - http://flybase.org/reports/FBgn0266776 non_protein_coding_gene - - - CR45241 - CR45241 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266471 gevuinanut - http://flybase.org/reports/FBgn0266471 gene - - - gevuinanut - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal "egg chamber,somatic clone,oocyte associated follicular epithelium,follicle cell" FBgn0267163 CG45603 - http://flybase.org/reports/FBgn0267163 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG45603 - CG45603 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0083302 E(smoDN)1700 Enhancer of smoDN 1700 http://flybase.org/reports/FBgn0083302 gene - - - E(smoDN)1700 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035643 CG13287 - http://flybase.org/reports/FBgn0035643 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - CG13287 IPR013087:Zinc finger C2H2-type CG13287 27-Aug-18 DroID_v2018_08 "Drer\prdm8, Drer\si:dkeyp-41f9.4, Drer\prdm8b" - Cele\F21D5.9 Xtro\prdm8 "Mmus\Zfp488, Mmus\Prdm8" "Hsap\ZNF488, Hsap\PRDM8" lethal DRSC09961 I 0.826555674 -1.604250697 -0.786428164 0.639982357 -0.773440048 -0.076948619 FBgn0085700 CG41573 - http://flybase.org/reports/FBgn0085700 protein_coding_gene - - - CG41573 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000512 dv divergent http://flybase.org/reports/FBgn0000512 - gene - - - "aea, dv" - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,semi-sterile" "wing,wing vein" FBgn0065437 l(2)SH1469 lethal (2) SH1469 http://flybase.org/reports/FBgn0065437 gene - - - "l(2)SH1469, l(2)SH2 1469" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0003398 shp shrimp http://flybase.org/reports/FBgn0003398 - gene - - - shp - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,male,reduced,male fertile,female fertile,visible,recessive" FBgn0266566 CG45105 - http://flybase.org/reports/FBgn0266566 protein_coding_gene - centrosome organization ; GO:0051297 | inferred from electronic annotation with InterPro:IPR031887 centrosome ; GO:0005813 | inferred from electronic annotation with InterPro:IPR031887 "CG45105, CG31291, CG5552, CG14878, CG34275" IPR031887:Serologically defined colon cancer antigen 8 CG45105 27-Aug-18 DroID_v2018_08 Drer\sdccag8 - - Xtro\sdccag8 Mmus\Sdccag8 Hsap\SDCCAG8 FBgn0060669 l(3)S079304b lethal (3) S079304b http://flybase.org/reports/FBgn0060669 gene - - - "0793/04, l(3)S079304b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0082333 HM801 HM801 http://flybase.org/reports/FBgn0082333 gene - - - HM801 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032707 CG10348 - http://flybase.org/reports/FBgn0032707 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - "CG10348, lincRNA.186" "IPR013087:Zinc finger C2H2-type, IPR011989:Armadillo-like helical" CG10348 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-263k4.2, Drer\mecom" "Scer\MSN2, Scer\MSN4, Scer\COM2" "Cele\odd-2, Cele\odd-1, Cele\egl-43" - "Mmus\Mecom, Mmus\Prdm16" "Hsap\PRDM16, Hsap\MECOM, Hsap\ZNF367" viable FBgn0261966 huc2L-12 hydroxyurea- and (or) caffeine-sensitive 2L-12 http://flybase.org/reports/FBgn0261966 gene - - - "huc2L-12, huc[2L-12]" - - 27-Aug-18 DroID_v2018_08 - - - - - - "chemical sensitive,somatic clone,lethal" "eye,somatic clone,drug conditional" FBgn0051174 CG31174 - http://flybase.org/reports/FBgn0051174 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG31174, BcDNA:SD11171" IPR009991:Dynactin subunit p22 CG31174 27-Aug-18 DroID_v2018_08 Drer\dctn3 - - - Mmus\Dctn3 Hsap\DCTN3 FBgn0031457 CG3077 - http://flybase.org/reports/FBgn0031457 protein_coding_gene phosphatidylinositol binding ; GO:0035091 | inferred from electronic annotation with InterPro:IPR001683 molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG3077, DmSNX21" IPR001683:Phox homologous domain CG3077 27-Aug-18 DroID_v2018_08 "Drer\snx20, Drer\snx21" - - Xtro\snx21 "Mmus\Snx20, Mmus\Snx21" "Hsap\SNX20, Hsap\SNX21" viable FBgn0041169 anon-82Aa anon-82Aa http://flybase.org/reports/FBgn0041169 gene - - - "cB151, anon-82Aa" - - 27-Aug-18 DroID_v2018_08 - - - - - - " embryonic stage | early , embryonic stage | stage 8-15 " "

ubiquitous , mesoderm

" FBgn0086171 nkd::Mmus\Nkd1 - http://flybase.org/reports/FBgn0086171 engineered_fusion_gene - - - nkd::Mmus\Nkd1 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible sternite FBgn0058098 CG40098 - http://flybase.org/reports/FBgn0058098 protein_coding_gene - - - CG40098 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260019 sancho-panza sancho panza http://flybase.org/reports/FBgn0260019 gene - - - sancho-panza - - 27-Aug-18 DroID_v2018_08 - - - - - - chorion | germline clone FBgn0259321 EP-323 - http://flybase.org/reports/FBgn0259321 gene - - - EP-323 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing vein,wing,chaeta" FBgn0264979 CG4267 - http://flybase.org/reports/FBgn0264979 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from electronic annotation with InterPro:IPR000734 lipase activity ; GO:0016298 | inferred from sequence or structural similarity with MGI:MGI:96820 lipid catabolic process ; GO:0016042 | inferred from sequence or structural similarity with MGI:MGI:96820 cellular_component ; GO:0005575 | no biological data available "CG4267, CG31686, Dmel_CG4267" "IPR033906:Lipase, N-terminal, IPR029058:Alpha/Beta hydrolase fold, IPR000734:Triacylglycerol lipase family, IPR013818:Lipase/vitellogenin" CG4267 27-Aug-18 DroID_v2018_08 "Drer\LOC100331214, Drer\LOC101884800, Drer\lpl, Drer\lipg, Drer\lipca" - Cele\irld-48 "Xtro\lpl, Xtro\lipg" "Mmus\Lpl, Mmus\Lipc, Mmus\Lipg" "Hsap\PLA1A, Hsap\LIPC, Hsap\LIPG, Hsap\LPL" DRSC00102 IE -0.497545512 -2.894494065 -0.610660615 -4.632974162 -1.167931397 -0.067808142 FBgn0262462 mir-iab-4 mir-iab-4 stem loop http://flybase.org/reports/FBgn0262462 miRNA_gene - - - "miR-iab-4, mir-iab-4-5p, mir-iab-4, iab-4, mir-iab4, miR-iab-4-3p, miR-iab-4-5p, miR-iab4, MIR-iab4, CR43043, iab-4-5p, CR33624, iab-4-3p, CR33623, mir-iab-4-3p, MIR-iab-4, dme-iab-4, dme-miR-iab-4" - CR43043 27-Aug-18 DroID_v2018_08 - - - - - - "visible,lethal,homeotic" "haltere,wing,wing margin" FBgn0013508 l(1)U3 lethal (1) U3 http://flybase.org/reports/FBgn0013508 - gene - - - "U-3, l(1)U3" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0264440 lncRNA:CR43858 - http://flybase.org/reports/FBgn0264440 non_protein_coding_gene - - - CR43858 - CR43858 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0027194 l(2)51Fb lethal (2) 51Fb http://flybase.org/reports/FBgn0027194 - gene - - - l(2)51Fb - - 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,recessive,lethal" FBgn0013702 mt:tRNA:Pro-TGG mitochondrial transfer RNA:Proline-TGG http://flybase.org/reports/FBgn0013702 FBgn0002867 tRNA_gene - - - "CR34088, mtdbD00006310, mt:tRNA:Pro-TGG, mt:tRNA:P" - CR34088 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0086400 BG02439 - http://flybase.org/reports/FBgn0086400 gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - BG02439 - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,smell perception defective,sleep defective" FBgn0033475 CG12129 - http://flybase.org/reports/FBgn0033475 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR004088 - - "cg12129, CG12129" "IPR019510:Protein kinase A anchor protein, nuclear localisation signal domain, IPR004087:K Homology domain, IPR004088:K Homology domain, type 1, IPR009097:Cyclic phosphodiesterase" CG12129 27-Aug-18 DroID_v2018_08 "Drer\ascc1, Drer\akap7" - Cele\C23H3.3 "Xtro\akap7, Xtro\ascc1" "Mmus\Ascc1, Mmus\Akap7" "Hsap\ASCC1, Hsap\AKAP7" viable FBgn0082346 HM431 HM431 http://flybase.org/reports/FBgn0082346 gene - - - HM431 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036236 CG6931 - http://flybase.org/reports/FBgn0036236 protein_coding_gene - - - CG6931 IPR018958:SMI1/KNR4-like domain CG6931 27-Aug-18 DroID_v2018_08 Drer\tpgs2 - - Xtro\tpgs2 Mmus\Tpgs2 Hsap\TPGS2 viable FBgn0050285 CG30285 - http://flybase.org/reports/FBgn0050285 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG30285 - CG30285 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0065567 l(2)SH0977 lethal (2) SH0977 http://flybase.org/reports/FBgn0065567 gene - - - "l(2)SH0977, l(2)SH2 0977" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0065291 l(2)SH2011 lethal (2) SH2011 http://flybase.org/reports/FBgn0065291 gene - - - "l(2)SH2011, l(2)SH2 2011" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0267446 Su(Ste):CR45796 Supressor of Stellate:CR45796 http://flybase.org/reports/FBgn0267446 non_protein_coding_gene - - - "Su(Ste):CR45796, CR45796" - CR45796 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267001 Ten-a Tenascin accessory http://flybase.org/reports/FBgn0267001 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR011041 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:O61307 protein homodimerization activity ; GO:0042803 | inferred from direct assay protein heterodimerization activity ; GO:0046982 | inferred from direct assay self proteolysis ; GO:0097264 | inferred from electronic annotation with InterPro:IPR022385 central complex development ; GO:0048036 | inferred from mutant phenotype synaptic target recognition ; GO:0008039 | inferred from direct assay synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype maintenance of presynaptic active zone structure ; GO:0048790 | inferred from mutant phenotype positive regulation of heterotypic cell-cell adhesion ; GO:0034116 | inferred from mutant phenotype synaptic target recognition ; GO:0008039 | inferred from mutant phenotype presynaptic membrane organization ; GO:0097090 | inferred from mutant phenotype synapse organization ; GO:0050808 | inferred from direct assay synaptic target attraction ; GO:0016200 | inferred from mutant phenotype regulation of homotypic cell-cell adhesion ; GO:0034110 | inferred from direct assay positive regulation of locomotion ; GO:0040017 | inferred from mutant phenotype neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype postsynaptic membrane organization ; GO:0001941 | inferred from mutant phenotype regulation of terminal button organization ; GO:2000331 | inferred from mutant phenotype synaptic vesicle membrane organization ; GO:0048499 | inferred from mutant phenotype cytoskeleton of presynaptic active zone ; GO:0048788 | inferred from mutant phenotype extracellular region ; GO:0005576 | inferred from sequence model presynaptic active zone ; GO:0048786 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity neuromuscular junction ; GO:0031594 | inferred from direct assay presynaptic membrane ; GO:0042734 | inferred from direct assay "Ten-a, CG42338, ten-a, cbd, CG2578, ten[a], Dmtena, tenA(AT)[[14]], 1.2, Ten[a], tenA, CG18182, CG2590, Ten11A, CG11270, CG32659, DmtenA, CG12720, CG15733" "IPR011041:Soluble quinoprotein glucose/sorbosone dehydrogenase, IPR022385:Rhs repeat-associated core, IPR011042:Six-bladed beta-propeller, TolB-like, IPR000742:EGF-like domain, IPR006530:YD repeat, IPR013032:EGF-like, conserved site, IPR013111:EGF-like domain, extracellular, IPR028916:Tox-GHH domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG42338 27-Aug-18 DroID_v2018_08 "Drer\tenm3, Drer\si:dkey-34l15.2, Drer\tnr, Drer\si:ch211-12m10.1, Drer\tenm4, Drer\tnw, Drer\tenm1, Drer\si:dkey-237h12.3, Drer\zgc:153720, Drer\tnc" - "Cele\drd-2, Cele\ten-1, Cele\F28B4.3" "Xtro\tnc, Xtro\tnr, Xtro\tenm4, Xtro\tnxb, Xtro\tnn" "Mmus\Tnxb, Mmus\Tnn, Mmus\Tenm2, Mmus\Tnc, Mmus\Tenm1, Mmus\Tenm4, Mmus\Tenm3, Mmus\Tnr" "Hsap\TENM1, Hsap\TENM2, Hsap\TENM3, Hsap\TENM4, Hsap\TNN, Hsap\TNC, Hsap\TNR" FBgn0051609 CG31609 - http://flybase.org/reports/FBgn0051609 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 - - "anon-AE003623.1, CG31609" "IPR002223:Pancreatic trypsin inhibitor Kunitz domain, IPR020901:Proteinase inhibitor I2, Kunitz, conserved site" CG31609 27-Aug-18 DroID_v2018_08 "Drer\paplnb, Drer\wu:fb59d01, Drer\paplna" - "Cele\tag-290, Cele\C34F6.1" Xtro\papln "Mmus\Spint3, Mmus\Wfikkn1, Mmus\Papln, Mmus\Adamts6, Mmus\Adamtsl4, Mmus\Thsd4" "Hsap\PAPLN, Hsap\ADAMTSL4, Hsap\WFIKKN1, Hsap\ADAMTSL1, Hsap\ADAMTS6, Hsap\THSD4" viable FBgn0002937 ninaB neither inactivation nor afterpotential B http://flybase.org/reports/FBgn0002937 FBgn0038171 protein_coding_gene "retinal isomerase activity ; GO:0004744 | inferred from direct assay beta-carotene 15,15'-monooxygenase activity ; GO:0003834 | inferred from direct assay inferred from mutant phenotype carotenoid dioxygenase activity ; GO:0010436 | inferred from direct assay" "oxidation-reduction process ; GO:0055114 | inferred from direct assay vitamin A biosynthetic process ; GO:0035238 | inferred from direct assay inferred from mutant phenotype vitamin biosynthetic process ; GO:0009110 | inferred from mutant phenotype carotene metabolic process ; GO:0016119 | inferred from direct assay rhodopsin biosynthetic process ; GO:0016063 | inferred from direct assay phototransduction, visible light ; GO:0007603 | inferred from mutant phenotype rhodopsin biosynthetic process ; GO:0016063 | inferred from mutant phenotype phototransduction, UV ; GO:0007604 | inferred from mutant phenotype phototransduction ; GO:0007602 | traceable author statement retinal metabolic process ; GO:0042574 | inferred from direct assay" - "RPE65, beta-diox, anon-WO0148162.1, anon-WO0148163.1, DRPE65, CG9347, ninaB" IPR004294:Carotenoid oxygenase CG9347 27-Aug-18 DroID_v2018_08 "Drer\bco1, Drer\bco1l, Drer\bco2a, Drer\bco2l, Drer\rpe65c, Drer\rpe65b, Drer\bco2b, Drer\rpe65a" - "Cele\bcmo-2, Cele\F49E10.2, Cele\bcmo-1" "Xtro\bco2, Xtro\rpe65, Xtro\LOC100487224" "Mmus\Bco1, Mmus\Bco2, Mmus\Rpe65" "Hsap\RPE65, Hsap\BCO1, Hsap\BCO2" "neurophysiology defective,courtship behavior defective,male,phototaxis defective,viable" "photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6,photoreceptor cell R7,photoreceptor cell R8,eye,rhabdomere" FBgn0028163 l(3)S034305 lethal (3) S034305 http://flybase.org/reports/FBgn0028163 gene - - - "0343/05, l(3)S034305" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0262711 ifm(2)RS4 - http://flybase.org/reports/FBgn0262711 gene - flight ; GO:0060361 | inferred from mutant phenotype adult somatic muscle development ; GO:0007527 | inferred from mutant phenotype - ifm(2)RS4 - - 27-Aug-18 DroID_v2018_08 - - - - - - "flightless,recessive" dorsal medial muscle FBgn0038285 CG6974 - http://flybase.org/reports/FBgn0038285 protein_coding_gene metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR001506 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR006026 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001506, InterPro:IPR006026" - CG6974 "IPR001506:Peptidase M12A, IPR006026:Peptidase, metallopeptidase, IPR024079:Metallopeptidase, catalytic domain, IPR034035:Astacin-like metallopeptidase domain" CG6974 27-Aug-18 DroID_v2018_08 "Drer\tll1, Drer\c6ast4, Drer\si:ch73-40a17.3, Drer\he1a, Drer\tnfaip6, Drer\npsn, Drer\LOC100003133, Drer\he1b, Drer\bmp1b, Drer\mep1a.2, Drer\he2, Drer\c6ast3, Drer\mep1b, Drer\c6ast1, Drer\LOC797085, Drer\bmp1a" - "Cele\nas-24, Cele\nas-38, Cele\nas-39, Cele\nas-7, Cele\nas-21, Cele\nas-28, Cele\nas-19, Cele\nas-9, Cele\nas-33, Cele\nas-6, Cele\toh-1, Cele\nas-10, Cele\nas-1, Cele\nas-22" "Xtro\LOC100492324, Xtro\accs, Xtro\cubn, Xtro\mep1b, Xtro\LOC100489456, Xtro\tnfaip6, Xtro\mep1a, Xtro\uvs.2, Xtro\bmp1, Xtro\tll1, Xtro\tll2" "Mmus\Tll2, Mmus\Astl, Mmus\Mep1b, Mmus\Tnfaip6, Mmus\Adgrg6, Mmus\Tll1, Mmus\Mep1a, Mmus\Bmp1, Mmus\Cubn" "Hsap\ASTL, Hsap\TNFAIP6, Hsap\TLL2, Hsap\MEP1A, Hsap\TLL1, Hsap\ADGRG6, Hsap\CUBN, Hsap\MEP1B, Hsap\BMP1" viable FBgn0082687 E(ftz)1819 E(ftz)1819 http://flybase.org/reports/FBgn0082687 gene - - - "1819, E(ftz)1819" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040173 l(1)G0344 lethal (1) G0344 http://flybase.org/reports/FBgn0040173 gene - - - l(1)G0344 - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0062676 EP2419 EP2419 http://flybase.org/reports/FBgn0062676 gene - - - "EP(2)2419, EP2419" - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "eye,ommatidium" FBgn0060519 l(3)S102908 lethal (3) S102908 http://flybase.org/reports/FBgn0060519 gene - - - "1029/08, l(3)S102908" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0041631 HSE Heat shock element http://flybase.org/reports/FBgn0041631 regulatory_region - - - HSE - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035103 Vdup1 Vitamin D[[3]] up-regulated protein 1 http://flybase.org/reports/FBgn0035103 protein_coding_gene - negative regulation of gene expression ; GO:0010629 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "vdup1, dvdup1, VDUP1, Vdup1, CG7047" "IPR011021:Arrestin-like, N-terminal, IPR011022:Arrestin C-terminal-like domain, IPR014756:Immunoglobulin E-set" CG7047 27-Aug-18 DroID_v2018_08 "Drer\arrdc1b, Drer\zgc:110626, Drer\LOC799768, Drer\arrdc3a, Drer\txnipb, Drer\zgc:110353, Drer\txnipa, Drer\arrdc2, Drer\arrdc1a, Drer\si:ch211-130m23.2, Drer\arrdc3b" "Scer\ALY2, Scer\ART5, Scer\ROD1, Scer\ROG3, Scer\ALY1, Scer\LDB19, Scer\CSR2, Scer\ECM21, Scer\RIM8" "Cele\arrd-27, Cele\arrd-25, Cele\arrd-6, Cele\arrd-8, Cele\arrd-13, Cele\arrd-18, Cele\arrd-5, Cele\arrd-22, Cele\arrd-14, Cele\arrd-19, Cele\arrd-7, Cele\arrd-11, Cele\arrd-4, Cele\arrd-10, Cele\arrd-1, Cele\arrd-15, Cele\arrd-16, Cele\arrd-3, Cele\arrd-12, Cele\arrd-2, Cele\rnh-1.2, Cele\arrd-24, Cele\arrd-23, Cele\arrd-9, Cele\arrd-17" "Xtro\arrdc2, Xtro\arrdc4, Xtro\arrdc3, Xtro\txnip" "Mmus\Txnip, Mmus\Arrdc2, Mmus\Arrdc3, Mmus\Arrdc5, Mmus\Arrdc4, Mmus\Arrdc1" "Hsap\ARRDC3, Hsap\TXNIP, Hsap\ARRDC4, Hsap\ARRDC1, Hsap\ARRDC5, Hsap\ARRDC2" viable FBgn0014070 Su(tor)3-91 Su(tor)3-91 http://flybase.org/reports/FBgn0014070 - gene - - - Su(tor)3-91 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0036005 pall pallbearer http://flybase.org/reports/FBgn0036005 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model protein polyubiquitination ; GO:0000209 | inferred from mutant phenotype SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model "pall, CG3428, FBXO1, Pall, PALL" IPR001810:F-box domain CG3428 27-Aug-18 DroID_v2018_08 Drer\fbxo28 - "Cele\fbxa-66, Cele\ZC247.2" Xtro\fbxo28 Mmus\Fbxo28 Hsap\FBXO28 viable FBgn0015853 anon-10Cf anon-10Cf http://flybase.org/reports/FBgn0015853 - gene - - - anon-10Cf - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004435 Galphaq G protein alpha q subunit http://flybase.org/reports/FBgn0004435 FBgn0004178 protein_coding_gene GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR000654 GTPase activity ; GO:0003924 | inferred from mutant phenotype GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with MGI:MGI:95776 G-protein beta/gamma-subunit complex binding ; GO:0031683 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 G-protein coupled receptor binding ; GO:0001664 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 signal transducer activity ; GO:0004871 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with RGDID:620770 metarhodopsin inactivation ; GO:0016060 | inferred from mutant phenotype regulation of neuromuscular synaptic transmission ; GO:1900073 | inferred from genetic interaction with FLYBASE:GluRIinferred by curator; FB:FBgn0046113 thermotaxis ; GO:0043052 | inferred from mutant phenotype stabilization of membrane potential ; GO:0030322 | inferred from genetic interaction with Itp-r83A thermotaxis ; GO:0043052 | inferred from direct assay endocytosis ; GO:0006897 | inferred from mutant phenotype activation of phospholipase C activity ; GO:0007202 | inferred from physical interaction with norpA axon midline choice point recognition ; GO:0016199 | inferred from mutant phenotype flight behavior ; GO:0007629 | inferred from genetic interaction with Itp-r83A phototransduction ; GO:0007602 | inferred from direct assay negative regulation of compound eye retinal cell programmed cell death ; GO:0046673 | inferred from mutant phenotype mucosal immune response ; GO:0002385 | inferred from mutant phenotype neuron cellular homeostasis ; GO:0070050 | inferred from genetic interaction with FLYBASE:GluRIinferred by curator; FB:FBgn0046113 rhodopsin mediated signaling pathway ; GO:0016056 | inferred from mutant phenotype phospholipase C-activating dopamine receptor signaling pathway ; GO:0060158 | inferred from biological aspect of ancestor with PANTHER:PTN000026396 cellular response to carbon dioxide ; GO:0071244 | inferred from mutant phenotype activation of phospholipase C activity ; GO:0007202 | inferred from genetic interaction with rdgB inferred from genetic interaction with norpA sensory perception of smell ; GO:0007608 | inferred from mutant phenotype phototransduction ; GO:0007602 | traceable author statement phototransduction ; GO:0007602 | inferred from expression pattern inferred from mutant phenotype adenylate cyclase-modulating G-protein coupled receptor signaling pathway ; GO:0007188 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 heterotrimeric G-protein complex ; GO:0005834 | inferred from sequence or structural similarity with MGI:MGI:95776 rhabdomere ; GO:0016028 | traceable author statement rhabdomere ; GO:0016028 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay inaD signaling complex ; GO:0016027 | inferred from direct assay heterotrimeric G-protein complex ; GO:0005834 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 "dgq, Galpha49b, dGqalpha, Galpha[[q]], G[q], Gq, Galphaq, Galpha, Gqalpha, G[[alphaq]], G[[q]], DGqalpha, G[[a]]q, Gaq, G[[q]]alpha, G alpha 49B, CG17759, dGaalpha, dGqalpha-49b, dGqa-49b, Gqa-3, Galpha49B, Dgq, DmGalpha[[q]], dGqalpha-3, DGq, G[[qalpha]], dG[[q]]alpha, DGalphaq, dgqalpha, dG[[alphaq]], DGalpha[[q]], G?q, Gqalpha[[e]], Gqalphae, Gqalpha{e}, galpha49B, GNAQ/11/14, Dromel_CG17759_galpha49b_mORF, dGq, sast, Gq/11" "IPR000654:G-protein alpha subunit, group Q, IPR001019:Guanine nucleotide binding protein (G-protein), alpha subunit, IPR011025:G protein alpha subunit, helical insertion, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG17759 27-Aug-18 DroID_v2018_08 "Drer\gna15.4, Drer\gnaia, Drer\gnaq, Drer\si:ch211-207c7.2, Drer\gna11a, Drer\gna14, Drer\gna15.1, Drer\gnaz, Drer\gnai3, Drer\gnat2, Drer\gnao1b, Drer\gna14a, Drer\gnat1, Drer\gna11b, Drer\gnav1, Drer\gna15.2, Drer\gnai2b, Drer\gnao1a, Drer\gnai1" "Scer\GPA1, Scer\GPA2" "Cele\gpa-4, Cele\gpa-7, Cele\egl-30, Cele\odr-3, Cele\goa-1, Cele\gpa-2, Cele\gpa-1, Cele\gpa-16, Cele\gpa-3" "Xtro\gnat2, Xtro\gnaq, Xtro\gna11, Xtro\gnaz, Xtro\gnai2, Xtro\gnat1, Xtro\gnao1, Xtro\gnai3, Xtro\gnai1, Xtro\gna14, Xtro\gna15" "Mmus\Gnaz, Mmus\Gnai1, Mmus\Gna11, Mmus\Gnat3, Mmus\Gnai3, Mmus\Gnai2, Mmus\Gna14, Mmus\Gnat2, Mmus\Gnao1, Mmus\Gnaq, Mmus\Gnat1, Mmus\Gna15" "Hsap\GNA14, Hsap\GNAI1, Hsap\GNAI3, Hsap\GNAT2, Hsap\GNA15, Hsap\GNAI2, Hsap\GNAZ, Hsap\GNAT1, Hsap\GNA11, Hsap\GNAO1, Hsap\GNAT3, Hsap\GNAQ" " adult stage , spermatogenesis && adult stage " " ocellus

, retina

, testis

, adult brain

, eye

, adult head

" adult stage " proboscis | restricted

, eye

, ocellus

, medulla

, rhabdomere

, lamina

, maxillary palpus

, antennal segment 3

, photoreceptor cell

" "lethal - all die before end of first instar larval stage,some die during first instar larval stage,neurophysiology defective,visual behavior defective,recessive,behavior defective,immune response defective,thermotaxis behavior defective,viable,chemosensitive behavior defective,flightless,partially,smell perception defective,heat sensitive,sensory perception defective,somatic clone,dominant,lethal - all die before end of larval stage,some die during larval stage,lethal,wild-type,neuroanatomy defective" "photoreceptor cell,rhabdomere,photoreceptor,eye photoreceptor cell,retina,conditional,adult olfactory receptor neuron ab11a,wing,adult olfactory receptor neuron Or59b,adult olfactory receptor neuron Gr21a/63a,somatic clone,fascicle | embryonic stage,pCC neuron,commissure | embryonic stage,neuropil | embryonic stage,adult olfactory receptor neuron Or42b,adult olfactory receptor neuron Or22,heat sensitive,dMP2 neuron" DRSC07432 E 0.661768117 0.294638196 1.880932623 0.870461472 0.450598843 0.343098473 FBgn0264569 lncRNA:CR43941 - http://flybase.org/reports/FBgn0264569 non_protein_coding_gene - - - CR43941 - CR43941 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034819 CG9877 - http://flybase.org/reports/FBgn0034819 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE26296, CG9877" - CG9877 27-Aug-18 DroID_v2018_08 - - "Cele\nlp-33, Cele\nlp-31, Cele\nlp-29" - - - DRSC04587 I 1.537782134 -0.365227241 0.224643899 1.419732769 -0.51172772 -0.238694484 FBgn0052529 Hers Histone gene-specific Epigenetic Repressor in late S phase http://flybase.org/reports/FBgn0052529 protein_coding_gene transcription regulatory region sequence-specific DNA binding ; GO:0000976 | inferred from direct assay chromatin binding ; GO:0003682 | inferred from biological aspect of ancestor with PANTHER:PTN000968522 chromatin silencing ; GO:0006342 | inferred from mutant phenotype heterochromatin assembly ; GO:0031507 | inferred from biological aspect of ancestor with PANTHER:PTN000968522 chromatin remodeling ; GO:0006338 | inferred from mutant phenotype inferred from genetic interaction with Su(var)205 inferred from genetic interaction with Su(var)3-9 inferred from physical interaction with Su(var)205 inferred from physical interaction with Su(var)3-9 inferred from genetic interaction with Su(var)205 inferred from genetic interaction with Su(var)3-9 inferred from physical interaction with Su(var)205 inferred from physical interaction with Su(var)3-9 inferred from genetic interaction with Su(var)205 inferred from genetic interaction with Su(var)3-9 inferred from physical interaction with Su(var)205 inferred from physical interaction with Su(var)3-9 inferred from genetic interaction with Su(var)205 inferred from genetic interaction with Su(var)3-9 inferred from physical interaction with Su(var)205 inferred from physical interaction with Su(var)3-9 inferred from genetic interaction with Su(var)205 inferred from genetic interaction with Su(var)3-9 inferred from physical interaction with Su(var)205 inferred from physical interaction with Su(var)3-9 inferred from genetic interaction with Su(var)205 inferred from genetic interaction with Su(var)3-9 inferred from physical interaction with Su(var)205 inferred from physical interaction with Su(var)3-9 inferred from genetic interaction with Su(var)205 inferred from genetic interaction with Su(var)3-9 inferred from physical interaction with Su(var)205 inferred from physical interaction with Su(var)3-9 imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype chromatin ; GO:0000785 | inferred from biological aspect of ancestor with PANTHER:PTN000968522 chromatin silencing complex ; GO:0005677 | inferred from biological aspect of ancestor with PANTHER:PTN000968522 "CG15619, CG11936, CG32529, Hers, HERS" "IPR001025:Bromo adjacent homology (BAH) domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG32529 27-Aug-18 DroID_v2018_08 "Drer\bahd1, Drer\LOC100331694" - - Xtro\bahd1 "Mmus\Tnrc18, Mmus\Bahd1" Hsap\BAHD1 "suppressor of variegation,viable,fertile" eye DRSC19429 K 1.048545568 1.163515932 -0.436466355 0.4944286 1.852608506 1.954492388 FBgn0032749 Phlpp PH domain leucine-rich repeat protein phosphatase http://flybase.org/reports/FBgn0032749 protein_coding_gene protein serine/threonine phosphatase activity ; GO:0004722 | inferred from direct assay inferred from mutant phenotype protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8INB9 protein serine/threonine phosphatase activity ; GO:0004722 | non-traceable author statement regulation of apoptotic process ; GO:0042981 | inferred from direct assay protein dephosphorylation ; GO:0006470 | inferred from direct assay inferred from mutant phenotype protein dephosphorylation ; GO:0006470 | non-traceable author statement cellular_component ; GO:0005575 | no biological data available "CT29458, PP2C, Phlpp, CG10493, dPHLPP" "IPR001611:Leucine-rich repeat, IPR001932:PPM-type phosphatase domain, IPR032675:Leucine-rich repeat domain, L domain-like, IPR003591:Leucine-rich repeat, typical subtype" CG10493 27-Aug-18 DroID_v2018_08 "Drer\tlr2, Drer\phlpp2, Drer\tlr21, Drer\phlpp1, Drer\tlr19, Drer\dnaaf1, Drer\shoc2" Scer\CYR1 "Cele\soc-2, Cele\F43C1.1" Xtro\phlpp2 "Mmus\Tlr2, Mmus\Dnaaf1, Mmus\Shoc2, Mmus\Phlpp2, Mmus\Phlpp1" "Hsap\DNAAF1, Hsap\TLR2, Hsap\PHLPP2, Hsap\PHLPP1, Hsap\SHOC2" viable FBgn0067346 l(3)95Ef lethal (3) 95Ef http://flybase.org/reports/FBgn0067346 gene - - - l(3)95Ef - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262386 mir-306 mir-306 stem loop http://flybase.org/reports/FBgn0262386 miRNA_gene - - - "mir-306, miR-306, dme-mir-306, 306, MIR-306, CR42914, CR33609, MiR-306, CR33610, mir-306*, miR-306S, mir-306S, miR-306-star, dme-miR-306, dme-miR-306-5p, miR-306/79/9b" - CR42914 27-Aug-18 DroID_v2018_08 - - - - - - "visible,lethal" "eye,wing,spermatocyte cyst" FBgn0015471 l(2)45ABa lethal (2) 45ABa http://flybase.org/reports/FBgn0015471 - gene - - - l(2)45ABa - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0259256 C684 - http://flybase.org/reports/FBgn0259256 gene - - - C684 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing,wing margin" FBgn0050121 lncRNA:CR30121 - http://flybase.org/reports/FBgn0050121 non_protein_coding_gene - - - "CG30121, CR30121, BcDNA:GH12850" - CR30121 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0036104 CG6418 - http://flybase.org/reports/FBgn0036104 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR011545 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 helicase activity ; GO:0004386 | inferred from sequence or structural similarity RNA secondary structure unwinding ; GO:0010501 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 - "DmRH27, cg6418, CG6418" "IPR000629:ATP-dependent RNA helicase DEAD-box, conserved site, IPR001650:Helicase, C-terminal, IPR011545:DEAD/DEAH box helicase domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR014014:RNA helicase, DEAD-box type, Q motif" CG6418 27-Aug-18 DroID_v2018_08 "Drer\ddx42, Drer\ddx46" "Scer\PRP5, Scer\DBP2" "Cele\C46F11.4, Cele\F53H1.1" "Xtro\ddx46, Xtro\ddx42" "Mmus\Ddx46, Mmus\Ddx42" "Hsap\DDX42, Hsap\DDX46" viable FBgn0005266 l(3)SG86 lethal (3) SG86 http://flybase.org/reports/FBgn0005266 - gene - - - l(3)SG86 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,heat sensitive,some die during larval stage" FBgn0086603 snoRNA:Or-CD2 - http://flybase.org/reports/FBgn0086603 snoRNA_gene - - - "snoRNA:Or-CD2, orphan-CD2, snoRNA:461, Dm-461, snoR461, CR33636, DmOr_cd2 snoRNA, snoRNA:Or-cd2, DmOr_cd2(SnoR461), chr2R:4608869..4608988, Or-CD2" - CR33636 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0014313 l(3)ry111 lethal (3) ry111 http://flybase.org/reports/FBgn0014313 - gene - - - l(3)ry111 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0051389 CG31389 - http://flybase.org/reports/FBgn0051389 protein_coding_gene - - - CG31389 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,partially lethal - majority die,visible,body color defective" "chaeta,supernumerary,trichogen cell,mesothoracic tergum" DRSC12860 E -0.078660134 0.317929658 1.667566496 -0.839669311 -0.417453656 0.525698745 FBgn0065389 l(2)SH1631 lethal (2) SH1631 http://flybase.org/reports/FBgn0065389 gene - - - "l(2)SH1631, l(2)SH2 1631" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0000193 Bl Bristle http://flybase.org/reports/FBgn0000193 - gene - - - "Sy, Sy[31l], Bl, bl" - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,dominant,lethal,recessive" "macrochaeta,eye" FBgn0086212 flt-2 - http://flybase.org/reports/FBgn0086212 gene - - - flt-2 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0084023 CG41462 - http://flybase.org/reports/FBgn0084023 protein_coding_gene - - - CG41462 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265902 lncRNA:CR44691 - http://flybase.org/reports/FBgn0265902 non_protein_coding_gene - - - "CR44691, lincRNA.1010" - CR44691 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266061 Su(var)301 - http://flybase.org/reports/FBgn0266061 gene - - - "Su(var)301, 301" - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,suppressor of variegation,dominant,non-suppressor of variegation" FBgn0005270 l(3)SG90 lethal (3) SG90 http://flybase.org/reports/FBgn0005270 - gene - - - "l(3)K60, l(3)SG90" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" imaginal disc FBgn0004649 yl yolkless http://flybase.org/reports/FBgn0004649 "FBgn0000732, FBgn0004043" protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097 vitellogenin receptor activity ; GO:0008196 | inferred from sequence or structural similarity" oogenesis ; GO:0048477 | traceable author statement oogenesis ; GO:0048477 | non-traceable author statement cytoplasmic vesicle ; GO:0031410 | inferred from direct assay coated vesicle ; GO:0030135 | inferred from direct assay "CT3114, DmYPR, LR13, fs(1)L186, fs(1)yolkless, fs(1)M25, fs(1)A148, fs(1)148, fs(1)K184, fs(1)yl, fs(1)M205, fs(1)L211, fs(1)L196, fs(1)L193, fs(1)5, CG1372, yl, Yl, YL" "IPR018097:EGF-like calcium-binding, conserved site, IPR011042:Six-bladed beta-propeller, TolB-like, IPR000033:LDLR class B repeat, IPR000152:EGF-type aspartate/asparagine hydroxylation site, IPR000742:EGF-like domain, IPR001881:EGF-like calcium-binding domain, IPR002172:Low-density lipoprotein (LDL) receptor class A repeat, IPR013032:EGF-like, conserved site, IPR023415:Low-density lipoprotein (LDL) receptor class A, conserved site, IPR026823:Complement Clr-like EGF domain" CG1372 27-Aug-18 DroID_v2018_08 "Drer\lrp2a, Drer\lrp5, Drer\lrp1ba, Drer\lrp1bb, Drer\egf, Drer\lrp1ab" "Scer\APM3, Scer\APM2, Scer\APM1" "Cele\lrp-1, Cele\lrp-2" "Xtro\egf, Xtro\lrp2" "Mmus\Lrp6, Mmus\Lrp4, Mmus\Lrp1b, Mmus\C9, Mmus\Lrp2, Mmus\Egf, Mmus\Lrp1, Mmus\Lrp5, Mmus\Gm19410" "Hsap\EGF, Hsap\LRP6, Hsap\LRP1, Hsap\LRP1B, Hsap\LRP2, Hsap\LRP5, Hsap\LRP4" oogenesis stage && adult stage | female ovary

"female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,female sterile soma-dependent,viable" "chorion,yolk granule,adult hemolymph,female,egg,maternal effect,stage S10 oocyte,stage S13 oocyte,stage S14 oocyte,coated pit,coated vesicle,stage S10 oocyte & clathrin-coated vesicle" FBgn0004608 fur fused rhabdomeres http://flybase.org/reports/FBgn0004608 - gene - - - fur - - 27-Aug-18 DroID_v2018_08 - - - - - - "neurophysiology defective,wild-type" "rhabdomere,optic lobe,retina,lamina,medulla" FBgn0065929 l(2)SH0139 lethal (2) SH0139 http://flybase.org/reports/FBgn0065929 gene - - - "l(2)SH0139, l(2)SH2 0139" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0039805 Cpr100A Cuticular protein 100A http://flybase.org/reports/FBgn0039805 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr100A, CG12045, DmelCpr100A" IPR000618:Insect cuticle protein CG12045 27-Aug-18 DroID_v2018_08 Drer\LOC100003040 - "Cele\math-34, Cele\F44F1.4, Cele\sdz-30" - "Mmus\2410137M14Rik, Mmus\H2-K1" - "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0038887 CG7907 - http://flybase.org/reports/FBgn0038887 protein_coding_gene RNA cap binding ; GO:0000339 | inferred from biological aspect of ancestor with PANTHER:PTN000275634 mRNA binding ; GO:0003729 | inferred from biological aspect of ancestor with PANTHER:PTN000275634 "mRNA cis splicing, via spliceosome ; GO:0045292 | inferred from electronic annotation with InterPro:IPR027159 mRNA splicing, via spliceosome ; GO:0000398 | inferred from biological aspect of ancestor with PANTHER:PTN000275634 mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000004732 mRNA export from nucleus ; GO:0006406 | inferred from biological aspect of ancestor with PANTHER:PTN000275634 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ; GO:0000184 | inferred from biological aspect of ancestor with PANTHER:PTN000275634 primary miRNA processing ; GO:0031053 | inferred from biological aspect of ancestor with PANTHER:PTN000275634" mRNA cap binding complex ; GO:0005845 | inferred from biological aspect of ancestor with PANTHER:PTN000275634 nuclear cap binding complex ; GO:0005846 | inferred from biological aspect of ancestor with PANTHER:PTN000275634 intracellular ribonucleoprotein complex ; GO:0030529 | inferred from biological aspect of ancestor with PANTHER:PTN000275634 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000275634 CG7907 "IPR003890:MIF4G-like, type 3, IPR015172:MIF4G-like, type 1, IPR015174:MIF4G-like, type 2, IPR027159:Nuclear cap-binding protein subunit 1, IPR016024:Armadillo-type fold" CG7907 27-Aug-18 DroID_v2018_08 - Scer\STO1 Cele\ncbp-1 Xtro\ncbp1 Mmus\Ncbp1 Hsap\NCBP1 FBgn0032381 Mal-B1 Maltase B1 http://flybase.org/reports/FBgn0032381 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR006047, InterPro:IPR015902" "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR006047, InterPro:IPR006589, InterPro:IPR013781" - "Mal-B1, CG14934, mal_B1, Drome_B1" "IPR006047:Glycosyl hydrolase, family 13, catalytic domain, IPR017853:Glycoside hydrolase superfamily" CG14934 27-Aug-18 DroID_v2018_08 "Drer\slc3a2a, Drer\zgc:158423, Drer\slc3a1, Drer\slc3a2b, Drer\si:dkey-202g17.3" "Scer\IMA5, Scer\IMA4, Scer\IMA1, Scer\IMA2, Scer\MAL32, Scer\MAL12, Scer\IMA3" "Cele\atgp-1, Cele\atgp-2" "Xtro\slc3a1, Xtro\slc3a2" "Mmus\Slc3a2, Mmus\Slc3a1" "Hsap\SLC3A2, Hsap\SLC3A1" viable DRSC02416 EK -0.704395479 0.714998552 3.899972179 0.729753206 -2.763082872 0.436859503 FBgn0003681 ten tenuis chaetae http://flybase.org/reports/FBgn0003681 - gene - - - ten - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive,viable,fertile" macrochaeta FBgn0028226 l(3)S005302a lethal (3) S005302a http://flybase.org/reports/FBgn0028226 gene - - - "0053/02, l(3)S005302, l(3)S005302a" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0030385 Ir11a Ionotropic receptor 11a http://flybase.org/reports/FBgn0030385 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model sensory perception of taste ; GO:0050909 | inferred from expression pattern detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "Ir11a, CT35969, CG15732, DmelIR11a, IR11a, Q9VYN4_DROME" IPR001638:Solute-binding protein family 3/N-terminal domain of MltF CG15732 27-Aug-18 DroID_v2018_08 "Drer\grid1b, Drer\grid1a, Drer\LOC100537813" - "Cele\glr-5, Cele\glr-8, Cele\glr-7" - "Mmus\Grik4, Mmus\Grid1" "Hsap\GRID2, Hsap\GRID1, Hsap\GRIK3, Hsap\GRIN2C" "viable,lethal" FBgn0044000 Su(rst)C40 Su(rst)C40 http://flybase.org/reports/FBgn0044000 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "C40, Su(rst)C40" - - 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0060658 l(3)S082807 lethal (3) S082807 http://flybase.org/reports/FBgn0060658 gene - - - "0828/07, l(3)S082807" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0029036 l(2)N36 lethal (2) N36 http://flybase.org/reports/FBgn0029036 gene - - - "N36, l(2)N36" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0259194 Ir94e Ionotropic receptor 94e http://flybase.org/reports/FBgn0259194 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "CG17379, DmelIR94e, Ir94e, IR94e, CG42298" - CG42298 27-Aug-18 DroID_v2018_08 - - Cele\glr-7 - - - viable FBgn0000833 fs(1)M15 female sterile (1) M15 http://flybase.org/reports/FBgn0000833 - gene - - - fs(1)M15 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,rescuable maternal effect,female sterile,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" egg FBgn0015921 cleo cleopatra http://flybase.org/reports/FBgn0015921 - gene - - - cleo - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,female fertile" embryonic/larval brain FBgn0058211 CG40211 - http://flybase.org/reports/FBgn0058211 protein_coding_gene - - - CG40211 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0014401 tru troupa http://flybase.org/reports/FBgn0014401 - gene - - - tru - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0261019 moi modigliani http://flybase.org/reports/FBgn0261019 protein_coding_gene single-stranded telomeric DNA binding ; GO:0043047 | contributes_to inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q95RV2 "telomere capping ; GO:0016233 | inferred from mutant phenotype telomere capping ; GO:0016233 | inferred by curator from GO:0000782,GO:0043047 protection from non-homologous end joining at telomere ; GO:0031848 | inferred from mutant phenotype inferred from genetic interaction with mei-41 inferred from genetic interaction with tefu" "polytene chromosome interband ; GO:0005705 | inferred from direct assay telomere cap complex ; GO:0000782 | inferred from direct assay chromosome, telomeric region ; GO:0000781 | inferred from direct assay" "moi, l(3)S096713, 0967/13, Dromel_CG31241_FBtr0083570_dtl_uORF, tlu, Dtl uORF, DTLu, CG42350, l(3)CB02140, CG31241, DTL, uORF, DTL/Moi, Moi" - CG42350 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0011582 Dop1R1 Dopamine 1-like receptor 1 http://flybase.org/reports/FBgn0011582 - protein_coding_gene "G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity dopamine neurotransmitter receptor activity ; GO:0004952 | inferred from sequence or structural similarity dopamine neurotransmitter receptor activity, coupled via Gs ; GO:0001588 | inferred from direct assay dopamine neurotransmitter receptor activity, coupled via Gs ; GO:0001588 | inferred from mutant phenotype" associative learning ; GO:0008306 | inferred from mutant phenotype memory ; GO:0007613 | inferred from mutant phenotype regulation of presynaptic cytosolic calcium ion concentration ; GO:0099509 | inferred from mutant phenotype thermotaxis ; GO:0043052 | inferred from mutant phenotype dopamine receptor signaling pathway ; GO:0007212 | inferred from sequence or structural similarity response to starvation ; GO:0042594 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype response to odorant ; GO:1990834 | inferred from mutant phenotype learning ; GO:0007612 | inferred from mutant phenotype thermosensory behavior ; GO:0040040 | inferred from mutant phenotype visual learning ; GO:0008542 | inferred from mutant phenotype adenylate cyclase-activating dopamine receptor signaling pathway ; GO:0007191 | inferred from direct assay regulation of olfactory learning ; GO:0090328 | inferred from mutant phenotype response to sucrose ; GO:0009744 | inferred from mutant phenotype cellular response to sucrose stimulus ; GO:0071329 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from electronic annotation with InterPro:IPR000929 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred from sequence model "DopR, Dumb, Dmdop1, dDA1, DA1, dDA1/DmDOP1, DmDop1, DopR35F, CG9652, dumb, D-Dop1, DopR1, DmDOP1, Dop1R1, DR1, DRD1, dopr" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR000929:Dopamine receptor family, IPR017452:GPCR, rhodopsin-like, 7TM" CG9652 27-Aug-18 DroID_v2018_08 "Drer\drd7, Drer\LOC567498, Drer\drd1a, Drer\hrh4, Drer\drd6b, Drer\drd1b, Drer\hrh3, Drer\LOC563567, Drer\LOC101886918, Drer\LOC100331077" - Cele\dop-1 "Xtro\drd1c, Xtro\drd1, Xtro\drd5, Xtro\adra2b" "Mmus\Hrh4, Mmus\Drd1, Mmus\Drd5, Mmus\Adra1a, Mmus\Hrh3" "Hsap\HRH3, Hsap\ADRA1A, Hsap\DRD5, Hsap\HRH4, Hsap\DRD1" "learning defective,flight defective,lethal,some die during immature adult stage,recessive,partially lethal - majority die,male,courtship behavior defective,memory defective,viable,fertile,hyperactive,chemical conditional,hypoactive,thermotaxis behavior defective" DRSC16652 IE -0.728094939 -2.102660702 -0.146151673 -2.955447966 0.544773039 0.55029531 FBgn0086678 fs(3)H813 - http://flybase.org/reports/FBgn0086678 gene - - - "fs(3)H813, H813" - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive" FBgn0039860 CG1792 - http://flybase.org/reports/FBgn0039860 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN001227002 DNA binding ; GO:0003677 | inferred from direct assay" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from biological aspect of ancestor with PANTHER:PTN001227002" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001227002 CG1792 "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG1792 27-Aug-18 DroID_v2018_08 "Drer\bcl6ab, Drer\znf341, Drer\znf408, Drer\si:dkeyp-2e4.7, Drer\znf770, Drer\si:dkey-262g12.7" Scer\AZF1 "Cele\Y37F4.6, Cele\ztf-23, Cele\Y55F3AM.14, Cele\blmp-1, Cele\klf-3, Cele\eor-1, Cele\lin-29, Cele\M03D4.4" - "Mmus\Zfp110, Mmus\Zfp24, Mmus\Mtf1, Mmus\Zfp369, Mmus\Zscan5b, Mmus\Zfp341, Mmus\Zfp810, Mmus\Rbak, Mmus\Zfp445" "Hsap\ZNF281, Hsap\ZNF8, Hsap\ZNF274, Hsap\ZNF221, Hsap\ZNF284, Hsap\ZNF341, Hsap\MTF1, Hsap\ZNF560, Hsap\ZNF784, Hsap\ZNF398" "viable,fertile" FBgn0061474 28SrRNA 28SrRNA http://flybase.org/reports/FBgn0061474 rRNA_gene - - - "28S rRNA, 28S, 28S rDNA, 28s rRNA, 28S RNA, NEST:bs30g02, NEST:bs17g11, NEST:bs15g08, NEST:bs10c09, BEST:HL03427, BEST:HL02977, BEST:HL02093, BEST:LD41653, 28SRNA, 28SrRNA, 28S DNA, Mgn570" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0016068 slbo::Rat\C-EBP-delta C-EBP-delta http://flybase.org/reports/FBgn0016068 - engineered_fusion_gene - - - "slbo::Rat\C/EBP-delta, slbo::Rat\C-EBP-delta" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0020796 oculi-rugosissimi oculi rugosissimi http://flybase.org/reports/FBgn0020796 - gene - - - "or, oculi-rugosissimi" - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,viable" ommatidium FBgn0039130 CG5854 - http://flybase.org/reports/FBgn0039130 protein_coding_gene coenzyme binding ; GO:0050662 | inferred from electronic annotation with InterPro:IPR001509 catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR001509 - - "anon-WO0118547.306, CG5854" "IPR001509:NAD-dependent epimerase/dehydratase, IPR016040:NAD(P)-binding domain" CG5854 27-Aug-18 DroID_v2018_08 "Drer\nsdhl, Drer\sdr42e2, Drer\hsd3b7, Drer\hsd3b2, Drer\hsd3b1" Scer\ERG26 Cele\F53B1.4 "Xtro\LOC100494546, Xtro\LOC100490622, Xtro\sdr42e1, Xtro\nsdhl, Xtro\hsd3b7" "Mmus\Hsd3b3, Mmus\Hsd3b5, Mmus\Sdr42e1, Mmus\Gm10681, Mmus\Gm4450, Mmus\Hsd3b1, Mmus\Hsd3b4, Mmus\Hsd3b6, Mmus\Hsd3b7, Mmus\Nsdhl, Mmus\Hsd3b2" "Hsap\NSDHL, Hsap\SDR42E2, Hsap\HSD3B2, Hsap\SDR42E1, Hsap\HSD3B7, Hsap\HSD3B1" viable FBgn0036526 CG13450 - http://flybase.org/reports/FBgn0036526 protein_coding_gene - - - CG13450 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040207 kat80 katanin 80 http://flybase.org/reports/FBgn0040207 protein_coding_gene microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR026962 microtubule binding ; GO:0008017 | inferred from sequence or structural similarity dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype microtubule severing ; GO:0051013 | inferred from sequence or structural similarity with NCBI_gi:3005599 microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity katanin complex ; GO:0008352 | inferred from sequence or structural similarity with NCBI_gi:3005599 cytosol ; GO:0005829 | inferred from direct assay "CG9910, CG13956, kat80, Kat80, Katanin80" "IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat, IPR011042:Six-bladed beta-propeller, TolB-like, IPR026962:Katanin p80 subunit B1, IPR028021:Katanin p80 subunit, C-terminal" CG13956 27-Aug-18 DroID_v2018_08 "Drer\katnbl1, Drer\katnb1, Drer\wdr90" Scer\PRP4 "Cele\F47G4.4, Cele\F47G4.5" "Xtro\katnb1, Xtro\wdr90, Xtro\katnbl1" "Mmus\Wdr90, Mmus\Katnbl1, Mmus\Katnb1" "Hsap\KATNBL1, Hsap\KATNB1" "viable,body color defective,planar polarity defective" "mesothoracic tergum,dorsal appendage" FBgn0015336 CG15865 - http://flybase.org/reports/FBgn0015336 - protein_coding_gene - - - "anon-15Ab, CG15865" IPR024810:Mab-21 domain CG15865 27-Aug-18 DroID_v2018_08 "Drer\mb21d2, Drer\mab21l2, Drer\si:dkey-11f12.2, Drer\mab21l3, Drer\LOC556707, Drer\mab21l1" - - "Xtro\mb21d2, Xtro\mab21l1" "Mmus\Mab21l2, Mmus\Mb21d2, Mmus\Mab21l3, Mmus\Mab21l1, Mmus\2310007B03Rik, Mmus\Tmem102" "Hsap\MB21D2, Hsap\MAB21L3, Hsap\TMEM102, Hsap\MAB21L2, Hsap\C2orf54, Hsap\MAB21L1" viable DRSC19733 K -0.292763599 0.37776838 0.125075029 0.636934779 1.833469416 -0.679733593 FBgn0263039 lncRNA:CR43334 - http://flybase.org/reports/FBgn0263039 non_protein_coding_gene - - - "CR43334, pri-bantam" - CR43334 27-Aug-18 DroID_v2018_08 - - - - - - visible wing FBgn0065326 l(2)SH1897 lethal (2) SH1897 http://flybase.org/reports/FBgn0065326 gene - - - l(2)SH1897 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0003367 sf safranin http://flybase.org/reports/FBgn0003367 FBgn0000461 gene - - - "dki, sf" - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive,eye color defective" "pigment cell,Malpighian tubule" FBgn0259280 C517 - http://flybase.org/reports/FBgn0259280 gene - - - C517 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing vein,wing,chaeta,ectopic" FBgn0002004 l(2)36Bc lethal (2) 36Bc http://flybase.org/reports/FBgn0002004 - gene - - - "l(2L)HT-10, l(2)HT-10, l(2)36Bc" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0265809 lncRNA:CR44598 - http://flybase.org/reports/FBgn0265809 non_protein_coding_gene - - - "lincRNA.119, CR44598" - CR44598 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265717 lncRNA:CR44524 - http://flybase.org/reports/FBgn0265717 non_protein_coding_gene - - - "lincRNA.976, CR44524" - CR44524 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002332 l(3)87Ae lethal (3) 87Ae http://flybase.org/reports/FBgn0002332 - gene - - - "ck12, l(3)ck12, l(3)87Ae" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die" Malpighian tubule FBgn0030223 CG2111 - http://flybase.org/reports/FBgn0030223 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 peptide binding ; GO:0042277 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 metalloaminopeptidase activity ; GO:0070006 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 peptide catabolic process ; GO:0043171 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 phagocytosis ; GO:0006909 | inferred from mutant phenotype proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 "pepCG2111, CG2111" "IPR024571:ERAP1-like C-terminal domain, IPR001930:Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR014782:Peptidase M1, membrane alanine aminopeptidase, N-terminal, IPR034016:Aminopeptidase N-type" CG2111 27-Aug-18 DroID_v2018_08 "Drer\anpepb, Drer\si:ch211-106j24.1, Drer\si:ch211-149p5.1, Drer\erap2, Drer\anpepa, Drer\npepps, Drer\erap1b, Drer\erap1a, Drer\enpep, Drer\si:ch211-198g19.1, Drer\lnpep, Drer\si:ch211-276a23.5" "Scer\AAP1, Scer\APE2, Scer\TMA108" "Cele\T16G12.1, Cele\Y53F4B.20, Cele\F49B2.6, Cele\T07F10.1, Cele\T12E12.6, Cele\Y67D8C.9, Cele\pam-1, Cele\VB0395L.1, Cele\R03G8.4, Cele\R03G8.6, Cele\AC3.5, Cele\mnp-1, Cele\Y42A5A.1" "Xtro\enpep, Xtro\lnpep, Xtro\erap1, Xtro\lvrn, Xtro\npepps, Xtro\anpep" "Mmus\Enpep, Mmus\Erap1, Mmus\Npepps, Mmus\Lvrn, Mmus\Anpep, Mmus\Trhde, Mmus\Lnpep" "Hsap\ANPEP, Hsap\NPEPPS, Hsap\LVRN, Hsap\ERAP2, Hsap\TRHDE, Hsap\LNPEP, Hsap\ENPEP, Hsap\ERAP1" "viable,fertile,visible" "chaeta,supernumerary" FBgn0038918 CG6690 - http://flybase.org/reports/FBgn0038918 protein_coding_gene protein disulfide isomerase activity ; GO:0003756 | inferred from biological aspect of ancestor with PANTHER:PTN000528008 flavin-linked sulfhydryl oxidase activity ; GO:0016971 | inferred from biological aspect of ancestor with PANTHER:PTN000528008 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR017905 cell redox homeostasis ; GO:0045454 | inferred from electronic annotation with InterPro:IPR013766 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern integral component of Golgi membrane ; GO:0030173 | inferred from biological aspect of ancestor with PANTHER:PTN000528008 extracellular space ; GO:0005615 | inferred from direct assay extracellular region ; GO:0005576 | inferred from sequence model CG6690 "IPR012336:Thioredoxin-like fold, IPR013766:Thioredoxin domain, IPR017905:ERV/ALR sulfhydryl oxidase domain" CG6690 27-Aug-18 DroID_v2018_08 "Drer\qsox2, Drer\qsox1" - "Cele\T10H10.2, Cele\F47B7.2, Cele\F35G2.1" "Xtro\qsox2, Xtro\qsox1" "Mmus\Qsox2, Mmus\Qsox1" "Hsap\QSOX1, Hsap\QSOX2" viable FBgn0040820 CG14146 - http://flybase.org/reports/FBgn0040820 protein_coding_gene - - - CG14146 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0029041 l(2)F2 lethal (2) F2 http://flybase.org/reports/FBgn0029041 gene - - - "F2, l(2)F2" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0000706 fltL flight defective L http://flybase.org/reports/FBgn0000706 - gene - - - fltL - - 27-Aug-18 DroID_v2018_08 - - - - - - flightless FBgn0004913 Gnf1 Germ line transcription factor 1 http://flybase.org/reports/FBgn0004913 "FBgn0010351, FBgn0020380, FBgn0025510" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959, InterPro:IPR012178, InterPro:IPR013725 DNA clamp loader activity ; GO:0003689 | inferred from electronic annotation with InterPro:IPR012178, InterPro:IPR013725 DNA binding ; GO:0003677 | inferred from direct assay DNA binding ; GO:0003677 | non-traceable author statement" "DNA replication ; GO:0006260 | inferred from electronic annotation with InterPro:IPR008921, InterPro:IPR012178, InterPro:IPR013725 DNA repair ; GO:0006281 | inferred from electronic annotation with InterPro:IPR012178 lateral inhibition ; GO:0046331 | inferred from mutant phenotype DNA replication ; GO:0006260 | non-traceable author statement dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype" "DNA replication factor C complex ; GO:0005663 | inferred from electronic annotation with InterPro:IPR012178, InterPro:IPR013725 microtubule associated complex ; GO:0005875 | inferred from direct assay DNA replication factor C complex ; GO:0005663 | non-traceable author statement nucleus ; GO:0005634 | inferred from direct assay" "dRF-Cp140, RFC, RF-C 140, ONF-CAACAA, GTF-1, gtf1, RfC140, Gtf1, Gnf-1, CG1119, Gnf1, gnf1, RfC, DmRFC1, RFC1, rfc1, dRFC140" "IPR001357:BRCT domain, IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR012178:Replication factor C subunit 1, IPR013725:DNA replication factor RFC1, C-terminal, IPR008921:DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG1119 27-Aug-18 DroID_v2018_08 Drer\rfc1 Scer\RFC1 Cele\rfc-1 Xtro\rfc1 Mmus\Rfc1 Hsap\RFC1 "lethal,recessive,neuroanatomy defective,viable,visible" "dorsal multidendritic neuron ddaD,dorsal multidendritic neuron ddaC,embryonic/larval neuroblast,ganglion mother cell,chaeta,trichogen cell,mesothoracic tergum" DRSC12351 IE -0.717906792 -1.755126068 -1.760259825 -1.436493771 0.746828196 0.275440347 FBgn0085561 CG41229 - http://flybase.org/reports/FBgn0085561 protein_coding_gene - - - CG41229 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0003052 pe petit http://flybase.org/reports/FBgn0003052 - gene - - - pe - - 27-Aug-18 DroID_v2018_08 - - - - - - "female fertile,reduced,visible,viable" eye FBgn0262622 lncRNA:CR43146 - http://flybase.org/reports/FBgn0262622 non_protein_coding_gene - - - "CG43146, CR43146, lincRNA.537" - CR43146 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0050135 CG30135 - http://flybase.org/reports/FBgn0050135 protein_coding_gene - - - CG30135 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259527 B0010 - http://flybase.org/reports/FBgn0259527 gene - - - B0010 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible wing FBgn0001932 l(2)25Ee lethal (2) 25Ee http://flybase.org/reports/FBgn0001932 - gene - - - "jf29, l(2)gdh-9, l(2)jf29, l(2)gdh9, l(2)25Ee" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0011864 tRNA:Gly-GCC-1-6 transfer RNA:Glycine-GCC 1-6 http://flybase.org/reports/FBgn0011864 "FBgn0003779, FBgn0051982, FBgn0060220" tRNA_gene GGC codon-amino acid adaptor activity ; GO:0033462 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033462 cytosol ; GO:0005829 | inferred by curator from GO:0033462 "BG:DS04641.5, AE002690.trna17-GlyGCC, tRNA:G:GCC:AE002690-e, CR31982, tRNA:gly3:35Bc, tRNA[Gly-GCC], chr2L.trna26-GlyGCC, tRNA-Gly-GCC-1-6, tRNA:Gly-GCC-1-6, tRNA:G3:35Bc, GGC" - CR31982 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036627 Gagr Gag-related http://flybase.org/reports/FBgn0036627 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG4680, Gagr, Grp" - CG4680 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0023059 l(1)2Ec lethal (1) 2Ec http://flybase.org/reports/FBgn0023059 - gene - - - "D3/36.6, l(1)2Ec" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0086884 Wed - http://flybase.org/reports/FBgn0086884 gene - - - Wed - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive,male fertile,viable,female,poor,male,visible,dominant" "eye,ommatidium" FBgn0052673 Rab9E Rab at 9E http://flybase.org/reports/FBgn0052673 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579, InterPro:IPR005225 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11" Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 endocytic recycling ; GO:0032456 | inferred from biological aspect of ancestor with PANTHER:PTN001178320 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN001178320 vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 endosome membrane ; GO:0010008 | inferred from biological aspect of ancestor with PANTHER:PTN001178320 "anon-AE003451.2, Rab9E, CG32673" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG32673 27-Aug-18 DroID_v2018_08 "Drer\rab33a, Drer\rab35b, Drer\rab1aa, Drer\rab35a, Drer\zgc:171927, Drer\rab1bb, Drer\rabl6a, Drer\rab1ab, Drer\si:dkey-16l2.16, Drer\rab19, Drer\rabl6b, Drer\rab1ba, Drer\rsg1, Drer\zgc:101559, Drer\rab43, Drer\rab33ba" "Scer\YPT1, Scer\TEM1" "Cele\rab-28, Cele\rab-35" "Xtro\rab1a, Xtro\rab19, Xtro\rabl6, Xtro\rab33a, Xtro\rab28, Xtro\rab33b" "Mmus\Rab28, Mmus\Rabl6, Mmus\Rab33b, Mmus\Rab19, Mmus\Rab43, Mmus\Rab1b, Mmus\Rab33a, Mmus\Rsg1, Mmus\Rab1a, Mmus\Rab35" "Hsap\RAB43, Hsap\RAB35, Hsap\RAB1B, Hsap\RAB19, Hsap\RSG1, Hsap\RAB28, Hsap\RAB33B, Hsap\RAB33A, Hsap\RABL6, Hsap\RAB1A" FBgn0033724 CG8501 - http://flybase.org/reports/FBgn0033724 protein_coding_gene - - cell surface ; GO:0009986 | inferred from biological aspect of ancestor with PANTHER:PTN001048184 CG8501 - CG8501 27-Aug-18 DroID_v2018_08 - - Cele\F35C5.11 - - - FBgn0045487 Gr36a Gustatory receptor 36a http://flybase.org/reports/FBgn0045487 protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 taste receptor activity ; GO:0008527 | inferred from sequence or structural similarity taste receptor activity ; GO:0008527 | non-traceable author statement sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of taste ; GO:0050909 | inferred from sequence or structural similarity chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of taste ; GO:0050909 | non-traceable author statement male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 integral component of membrane ; GO:0016021 | non-traceable author statement "CG31747, GrLU1, Gr36B1, LU.1, GRLU.1, Gr36a, GR36a" IPR013604:7TM chemoreceptor CG31747 27-Aug-18 DroID_v2018_08 - - "Cele\gur-3, Cele\lite-1" - - - viable FBgn0015369 bushy bushy http://flybase.org/reports/FBgn0015369 - gene - - - "bsh, bushy" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032105 borr borealin-related http://flybase.org/reports/FBgn0032105 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with shrb DNA binding ; GO:0003677 | inferred from direct assay "mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype mitotic sister chromatid segregation ; GO:0000070 | inferred from biological aspect of ancestor with PANTHER:PTN001815752 mitotic cell cycle, embryonic ; GO:0045448 | inferred from mutant phenotype histone phosphorylation ; GO:0016572 | inferred from mutant phenotype protein localization ; GO:0008104 | inferred from mutant phenotype" spindle midzone ; GO:0051233 | inferred from direct assay kinetochore ; GO:0000776 | colocalizes_with inferred from direct assay chromosome passenger complex ; GO:0032133 | inferred from direct assay meiotic spindle midzone ; GO:1990385 | colocalizes_with inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay chromatin ; GO:0000785 | inferred from direct assay "CG4454, Bor, dBor, borr, Borr, BORR" IPR018867:Cell division protein borealin CG4454 27-Aug-18 DroID_v2018_08 "Drer\cdca8, Drer\cdca9" - - "Xtro\cdca9, Xtro\cdca8" Mmus\Cdca8 Hsap\CDCA8 "mitotic cell cycle defective,visible,partially lethal - majority die,some die during pupal stage,increased cell death,somatic clone,cell size defective,Minute,viable,lethal - all die before end of embryonic stage,some die during embryonic stage" "chromatin,trichogen cell,mesothoracic tergum,ventral nerve cord & nucleus,brain & nucleus,nucleus | somatic clone,spindle | somatic clone,leg,somatic clone,eye,wing,wing hair,ectopic,wing margin bristle" FBgn0060671 l(3)S078709 lethal (3) S078709 http://flybase.org/reports/FBgn0060671 gene - - - "0787/09, l(3)S078709" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0265904 lncRNA:CR44693 - http://flybase.org/reports/FBgn0265904 non_protein_coding_gene - - - CR44693 - CR44693 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037376 Hat1 Histone acetyltransferase 1 http://flybase.org/reports/FBgn0037376 protein_coding_gene histone binding ; GO:0042393 | inferred from biological aspect of ancestor with PANTHER:PTN000248102 H4 histone acetyltransferase activity ; GO:0010485 | inferred from direct assay histone acetylation ; GO:0016573 | inferred from electronic annotation with InterPro:IPR017380 chromatin silencing at telomere ; GO:0006348 | inferred from electronic annotation with InterPro:IPR017380 positive regulation of innate immune response ; GO:0045089 | inferred from mutant phenotype CENP-A containing nucleosome assembly ; GO:0034080 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype nuclear chromatin ; GO:0000790 | inferred from biological aspect of ancestor with PANTHER:PTN000248102 "dmHAG409, CG2051, Hat1" "IPR016181:Acyl-CoA N-acyltransferase, IPR017380:Histone acetyltransferase type B, catalytic subunit, IPR019467:Histone acetyl transferase HAT1 N-terminal" CG2051 27-Aug-18 DroID_v2018_08 Drer\hat1 Scer\HAT1 Cele\hat-1 Xtro\hat1 Mmus\Hat1 Hsap\HAT1 viable FBgn0044477 EP1016 EP1016 http://flybase.org/reports/FBgn0044477 gene - - - EP1016 - - 27-Aug-18 DroID_v2018_08 - - - - - - neuroanatomy defective "intersegmental nerve,anterior fascicle & synapse" FBgn0069917 CG41135 - http://flybase.org/reports/FBgn0069917 protein_coding_gene - - - CG41135 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031946 CG7164 - http://flybase.org/reports/FBgn0031946 protein_coding_gene - - - "CG7164, Q9VLX3" - CG7164 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035890 CG13667 - http://flybase.org/reports/FBgn0035890 protein_coding_gene "FMN binding ; GO:0010181 | inferred from electronic annotation with InterPro:IPR001094, InterPro:IPR008254 NADPH-hemoprotein reductase activity ; GO:0003958 | inferred from electronic annotation with InterPro:IPR028879" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001094, InterPro:IPR001433, InterPro:IPR001709, InterPro:IPR003097, InterPro:IPR017927, InterPro:IPR017938, InterPro:IPR023173 biological_process ; GO:0008150 | no biological data available" - CG13667 "IPR001433:Oxidoreductase FAD/NAD(P)-binding, IPR001709:Flavoprotein pyridine nucleotide cytochrome reductase, IPR003097:FAD-binding, type 1, IPR008254:Flavodoxin/nitric oxide synthase, IPR017927:Ferredoxin reductase-type FAD-binding domain, IPR017938:Riboflavin synthase-like beta-barrel, IPR028879:NADPH-dependent diflavin oxidoreductase 1, IPR029039:Flavoprotein-like domain, IPR001094:Flavodoxin-like" CG13667 27-Aug-18 DroID_v2018_08 "Drer\imp4, Drer\ndor1" "Scer\NCP1, Scer\TAH18" "Cele\fre-1, Cele\ZK795.3" "Xtro\imp4, Xtro\ndor1" "Mmus\Imp4, Mmus\Ndor1" "Hsap\NDOR1, Hsap\IMP4" viable FBgn0033177 CG11141 - http://flybase.org/reports/FBgn0033177 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG11141 "IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain, IPR029772:Tectonin beta-propeller repeat-containing protein 2" CG11141 27-Aug-18 DroID_v2018_08 "Drer\hps5, Drer\tecpr2" - Cele\W09G3.6 "Xtro\hps5, Xtro\tecpr2" "Mmus\Hps5, Mmus\Tecpr2" "Hsap\TECPR2, Hsap\HPS5" "viable,fertile,visible" trichogen cell FBgn0024259 acd(2)5N17 auditory courtship defective 5N17 http://flybase.org/reports/FBgn0024259 - gene molecular_function ; GO:0003674 | no biological data available auditory behavior ; GO:0031223 | inferred from mutant phenotype male courtship behavior ; GO:0008049 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available acd(2)5N17 - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,auditory perception defective" FBgn0013687 mt:ori mitochondrial origin http://flybase.org/reports/FBgn0013687 FBgn0002867 - - - - mt:ori - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039796 CG12069 - http://flybase.org/reports/FBgn0039796 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR000961, InterPro:IPR002290 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement cAMP-dependent protein kinase activity ; GO:0004691 | inferred from sequence or structural similarity with HGNC:9380" protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with HGNC:9380 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement cAMP-dependent protein kinase complex ; GO:0005952 | inferred from sequence or structural similarity with HGNC:9380 "CG12069, Pka-like" "IPR000719:Protein kinase domain, IPR000961:AGC-kinase, C-terminal, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain" CG12069 27-Aug-18 DroID_v2018_08 "Drer\prkg1b, Drer\LOC556339, Drer\prkacba, Drer\prkacaa, Drer\prkg2, Drer\prkx, Drer\sgk2b, Drer\prkacbb, Drer\prkacab" "Scer\YPK3, Scer\TPK1, Scer\TPK2, Scer\TPK3" "Cele\kin-1, Cele\F47F2.1" "Xtro\prkg2, Xtro\prkacb, Xtro\prkx, Xtro\prkaca" "Mmus\Prkg2, Mmus\Prkaca, Mmus\Prkacb, Mmus\Prkg1, Mmus\Prkx" "Hsap\PRKACB, Hsap\PRKACA, Hsap\PRKG2, Hsap\PRKG1, Hsap\PRKX, Hsap\PRKACG" "male sterile,viable" FBgn0011669 Mst57Db Male-specific RNA 57Db http://flybase.org/reports/FBgn0011669 FBgn0002859 protein_coding_gene molecular_function ; GO:0003674 | no biological data available post-mating behavior ; GO:0045297 | non-traceable author statement oviposition ; GO:0018991 | non-traceable author statement multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from sequence model extracellular space ; GO:0005615 | inferred from direct assay extracellular region ; GO:0005576 | non-traceable author statement "CG5016, mst-1, mst(2)ag-1, Mst57Db" - CG5016 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0050067 Obp50a Odorant-binding protein 50a http://flybase.org/reports/FBgn0050067 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 extracellular region ; GO:0005576 | inferred from sequence model "CG30067, anon-AE003814.2, Obp50a, DmelObp50a" IPR006170:Pheromone/general odorant binding protein CG30067 27-Aug-18 DroID_v2018_08 - - - - - - DRSC22152 K -0.432014595 0.335792788 -0.190516925 0.04012612 0.565493814 -2.486145714 FBgn0052723 CR32723 - http://flybase.org/reports/FBgn0052723 non_protein_coding_gene - - - CR32723 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260869 CG42579 - http://flybase.org/reports/FBgn0260869 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42579, HDC19846" - CG42579 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005160 l(2)G151 lethal (2) G151 http://flybase.org/reports/FBgn0005160 - gene - - - l(2)G151 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0014369 osho one shot http://flybase.org/reports/FBgn0014369 - gene - - - osho - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051710 CG31710 - http://flybase.org/reports/FBgn0051710 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG31710, EP2160" - CG31710 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0084120 tgl tangled http://flybase.org/reports/FBgn0084120 gene - - - tgl - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262398 mir-124 mir-124 stem loop http://flybase.org/reports/FBgn0262398 miRNA_gene - gene silencing by miRNA ; GO:0035195 | inferred from direct assay neuroblast proliferation ; GO:0007405 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype negative regulation of synaptic transmission ; GO:0050805 | inferred from mutant phenotype - "mir-124, miR-124, dme-mir-124, MIR-124, CR42937, Mir-124, CR33573, mir-124b, miR-124a, dme-miR-124, mir-124a" - CR42937 27-Aug-18 DroID_v2018_08 - - - - - - " embryonic stage , larval stage | first instar " FBgn0036835 CG14075 - http://flybase.org/reports/FBgn0036835 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - CG14075 - CG14075 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0004005 wdl wavoid-like http://flybase.org/reports/FBgn0004005 - gene - - - wdl - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,female semi-sterile,lethal,maternal effect" "wing,wing vein L5" FBgn0034822 RpL37b Ribosomal protein L37b http://flybase.org/reports/FBgn0034822 protein_coding_gene "structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR001569, InterPro:IPR011331, InterPro:IPR018267 structural constituent of ribosome ; GO:0003735 | traceable author statement RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000080456" "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR001569, InterPro:IPR011331, InterPro:IPR011332, InterPro:IPR018267 translation ; GO:0006412 | inferred from sequence model cytoplasmic translation ; GO:0002181 | traceable author statement" "ribosome ; GO:0005840 | inferred from electronic annotation with InterPro:IPR001569, InterPro:IPR011331, InterPro:IPR018267 cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement" "CG9873, RpL37b, Rpl37b" "IPR018267:Ribosomal protein L37e, conserved site, IPR011331:Ribosomal protein L37ae/L37e, IPR011332:Zinc-binding ribosomal protein, IPR001569:Ribosomal protein L37e" CG9873 27-Aug-18 DroID_v2018_08 Drer\rpl37 "Scer\RPL37A, Scer\RPL37B" "Cele\rpl-37, Cele\W01D2.1" Xtro\rpl37 "Mmus\Rpl37rt, Mmus\Rpl37" Hsap\RPL37 "viable,visible" trichogen cell FBgn0260249 GSd495 - http://flybase.org/reports/FBgn0260249 gene - - - GSd495 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0001528 l(1)11Ed lethal (1) 11Ed http://flybase.org/reports/FBgn0001528 - gene - - - l(1)11Ed - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,cell lethal,germline clone" FBgn0082986 snoRNA:Psi28S-2562 snoRNA:Psi28S-2562 http://flybase.org/reports/FBgn0082986 snoRNA_gene - - - "snoRNA:Psi28S-2562, psi28s-2562, Psi 28S-2562, CR34616, chr3R:16648632..16648732" - CR34616 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034440 CG10073 - http://flybase.org/reports/FBgn0034440 protein_coding_gene - - - CG10073 IPR007484:Peptidase M28 CG10073 27-Aug-18 DroID_v2018_08 Drer\LOC100330918 "Scer\PFF1, Scer\VPS70, Scer\APE3, Scer\YDR415C" "Cele\B0495.7, Cele\C44B7.11" Xtro\ermp1 Mmus\Ermp1 Hsap\ERMP1 viable FBgn0038832 CG15695 - http://flybase.org/reports/FBgn0038832 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR017849, InterPro:IPR017850" "metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR017849, InterPro:IPR017850" - "CG15695, gi7300665, gi21356013" "IPR004245:Protein of unknown function DUF229, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha, IPR017850:Alkaline-phosphatase-like, core domain" CG15695 27-Aug-18 DroID_v2018_08 - - "Cele\Y73F8A.35, Cele\Y38A10A.2, Cele\F10C2.3, Cele\T23E1.1, Cele\T07G12.3, Cele\F07C3.3, Cele\K03A11.4, Cele\Y41E3.1, Cele\F15H10.7, Cele\F32G8.2, Cele\R03G8.1, Cele\M03F8.5, Cele\F32D8.2, Cele\R03G8.3" - - - viable FBgn0062663 EP3186 EP3186 http://flybase.org/reports/FBgn0062663 gene - - - "EP(3)3186, EP3186" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265425 lncRNA:CR44337 - http://flybase.org/reports/FBgn0265425 non_protein_coding_gene - - - CR44337 - CR44337 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036019 Or67b Odorant receptor 67b http://flybase.org/reports/FBgn0036019 protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from mutant phenotype dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 "67b, 67B.2, CG14176, Or67b" "IPR004117:Olfactory receptor, insect" CG14176 27-Aug-18 DroID_v2018_08 - - - - - - "smell perception defective,viable" FBgn0020764 Alas Aminolevulinate synthase http://flybase.org/reports/FBgn0020764 - protein_coding_gene "pyridoxal phosphate binding ; GO:0030170 | inferred from electronic annotation with InterPro:IPR004839, InterPro:IPR010961 5-aminolevulinate synthase activity ; GO:0003870 | inferred from sequence or structural similarity with RGD:2084 5-aminolevulinate synthase activity ; GO:0003870 | inferred from sequence or structural similarity with UniProt:P22557 inferred from sequence or structural similarity with UniProtKB:P13196" chitin-based cuticle development ; GO:0040003 | inferred from mutant phenotype heme biosynthetic process ; GO:0006783 | inferred from sequence or structural similarity with UniProtKB:P13196 inferred from sequence or structural similarity with UniProtKB:P22557 mitochondrion ; GO:0005739 | inferred from reviewed computational analysis mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProt:P22557 inferred from sequence or structural similarity with UniProtKB:P13196 "Alas, CG3017, alas, ALAS" "IPR004839:Aminotransferase, class I/classII, IPR010961:Tetrapyrrole biosynthesis, 5-aminolevulinic acid synthase, IPR015421:Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015424:Pyridoxal phosphate-dependent transferase, IPR015422:Pyridoxal phosphate-dependent transferase, subdomain 2" CG3017 27-Aug-18 DroID_v2018_08 "Drer\gcat, Drer\alas2, Drer\alas1" Scer\HEM1 Cele\T25B9.1 "Xtro\alas2, Xtro\alas1" "Mmus\Alas1, Mmus\Gcat, Mmus\Alas2" "Hsap\ALAS1, Hsap\ALAS2, Hsap\GCAT" "small body,partially lethal - majority die,some die during pupal stage,lethal" "embryonic/first instar larval cuticle,embryonic/larval tracheal system,procuticle" FBgn0035951 CG5068 - http://flybase.org/reports/FBgn0035951 protein_coding_gene protein phosphatase regulator activity ; GO:0019888 | inferred from biological aspect of ancestor with PANTHER:PTN000367041 protein methylesterase activity ; GO:0051723 | inferred from biological aspect of ancestor with PANTHER:PTN000367039 protein demethylation ; GO:0006482 | inferred from biological aspect of ancestor with PANTHER:PTN000367039 - CG5068 "IPR000639:Epoxide hydrolase-like, IPR000073:Alpha/beta hydrolase fold-1, IPR016812:Protein phosphatase methylesterase, eukaryotic, IPR029058:Alpha/Beta hydrolase fold" CG5068 27-Aug-18 DroID_v2018_08 Drer\ppme1 Scer\PPE1 Cele\B0464.9 Xtro\ppme1 Mmus\Ppme1 Hsap\PPME1 viable FBgn0014974 l(1)13Fd lethal (1) 13Fd http://flybase.org/reports/FBgn0014974 - gene - - - "IX, l(1)IX, l(1)13Fd" - - 27-Aug-18 DroID_v2018_08 - - - - - - "wild-type,lethal,recessive" FBgn0060646 l(3)S083902b lethal (3) S083902b http://flybase.org/reports/FBgn0060646 gene - - - "0839/02, l(3)S083902b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0264505 lncRNA:CR43904 - http://flybase.org/reports/FBgn0264505 non_protein_coding_gene - - - CR43904 - CR43904 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033952 Adgf-E Adenosine deaminase-related growth factor E http://flybase.org/reports/FBgn0033952 protein_coding_gene "adenosine deaminase activity ; GO:0004000 | NOT inferred from sequence or structural similarity with Adgf-A, Adgf-D inferred from direct assay growth factor activity ; GO:0008083 | inferred from sequence or structural similarity with Adgf-A, Adgf-D" "adenosine catabolic process ; GO:0006154 | NOT inferred from sequence or structural similarity with Adgf-A, Adgf-D inferred from direct assay cell proliferation ; GO:0008283 | inferred from sequence or structural similarity with Adgf-A, Adgf-D" "extracellular space ; GO:0005615 | inferred from electronic annotation with InterPro:IPR006331, InterPro:IPR013659" "ADGF-E, CG10143, adgfe, Adgf-E" "IPR001365:Adenosine/AMP deaminase domain, IPR006331:Adenosine deaminase-related growth factor, IPR013659:Adenosine/AMP deaminase N-terminal, IPR032466:Metal-dependent hydrolase" CG10143 27-Aug-18 DroID_v2018_08 "Drer\cecr1a, Drer\adal, Drer\ada, Drer\cecr1b" Scer\AAH1 "Cele\C06G3.5, Cele\C44B7.12" "Xtro\ada.2, Xtro\ada, Xtro\adal, Xtro\cecr1" "Mmus\Adal, Mmus\Ada" "Hsap\ADAL, Hsap\ADA, Hsap\CECR1" FBgn0053651 CG33651 - http://flybase.org/reports/FBgn0053651 protein_coding_gene - - - "anon-EST:Liang-1.3, clone 1.3, CG33651" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264296 CG43774 - http://flybase.org/reports/FBgn0264296 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43774, CG10039" - CG43774 27-Aug-18 DroID_v2018_08 - "Scer\APC2, Scer\LTV1" Cele\apc-2 - Mmus\Anapc2 Hsap\ANAPC2 viable FBgn0263131 CG43373 - http://flybase.org/reports/FBgn0263131 protein_coding_gene adenylate cyclase activity ; GO:0004016 | inferred from electronic annotation with InterPro:IPR009398 adenylate cyclase activity ; GO:0004016 | non-traceable author statement guanylate cyclase activity ; GO:0004383 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 "cAMP biosynthetic process ; GO:0006171 | inferred from electronic annotation with InterPro:IPR009398 intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR001054, InterPro:IPR018297 signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 cGMP biosynthetic process ; GO:0006182 | inferred from biological aspect of ancestor with PANTHER:PTN000229249" "plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 guanylate cyclase complex, soluble ; GO:0008074 | inferred from biological aspect of ancestor with PANTHER:PTN000229249" "CG43373, CG12436, CG32158, AC, CG42513, Ago2" "IPR029787:Nucleotide cyclase, IPR001054:Adenylyl cyclase class-3/4/guanylyl cyclase, IPR009398:Adenylate cyclase, conserved domain, IPR018297:Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR032628:Adenylate cyclase, N-terminal" CG43373 27-Aug-18 DroID_v2018_08 "Drer\adcy6a, Drer\adcy6b, Drer\adcy1b, Drer\adcy2a, Drer\si:ch211-132f19.7, Drer\adcy5, Drer\si:dkey-206f10.1, Drer\adcy1a, Drer\adcy3a, Drer\adcy8, Drer\adcy2b, Drer\adcy7" - "Cele\acy-2, Cele\acy-4" "Xtro\adcy6, Xtro\adcy7, Xtro\dnajc27, Xtro\adcy1, Xtro\adcy4" "Mmus\Adcy1, Mmus\Adcy7, Mmus\Adcy6, Mmus\Adcy2, Mmus\Adcy4, Mmus\Adcy3, Mmus\Adcy8, Mmus\Adcy5" "Hsap\ADCY2, Hsap\ADCY1, Hsap\ADCY8, Hsap\ADCY7, Hsap\ADCY6, Hsap\ADCY4, Hsap\ADCY3, Hsap\ADCY5" FBgn0036246 CG17154 - http://flybase.org/reports/FBgn0036246 protein_coding_gene - - - CG17154 - CG17154 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0014891 Wedge Wedge http://flybase.org/reports/FBgn0014891 - gene - - - Wedge - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,dominant,lethal - all die before end of pupal stage,recessive,some die during pupal stage" eye FBgn0029121 Sras severas http://flybase.org/reports/FBgn0029121 protein_coding_gene cysteine-type endopeptidase activity ; GO:0004197 | inferred from biological aspect of ancestor with PANTHER:PTN000316030 metalloendopeptidase activity ; GO:0004222 | inferred from biological aspect of ancestor with PANTHER:PTN000316030 CAAX-box protein processing ; GO:0071586 | inferred from biological aspect of ancestor with PANTHER:PTN000316030 integral component of endoplasmic reticulum membrane ; GO:0030176 | inferred from biological aspect of ancestor with PANTHER:PTN000316030 "CG4852, Sras, FAC2_DROME" IPR003675:CAAX amino terminal protease CG4852 27-Aug-18 DroID_v2018_08 "Drer\rce1a, Drer\rce1b" Scer\RCE1 Cele\fce-2 Xtro\rce1 Mmus\Rce1 Hsap\RCE1 viable FBgn0028412 Mst33A Mst33A http://flybase.org/reports/FBgn0028412 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG6541, Mst33A" IPR009071:High mobility group box domain CG6541 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0267985 lncRNA:CR46252 - http://flybase.org/reports/FBgn0267985 non_protein_coding_gene - - - CR46252 - CR46252 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0017546 Rp34 Ribosomal protein 34 http://flybase.org/reports/FBgn0017546 - gene structural constituent of ribosome ; GO:0003735 | non-traceable author statement translation ; GO:0006412 | non-traceable author statement ribosome ; GO:0005840 | non-traceable author statement "rp34, Rp34" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259623 B0531 - http://flybase.org/reports/FBgn0259623 gene - - - B0531 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible wing FBgn0004826 fs(2)ltoHC44 female sterile (2) ltoHC44 http://flybase.org/reports/FBgn0004826 - gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(2)ltoHC44 - - 27-Aug-18 DroID_v2018_08 - - - - - - female sterile FBgn0031757 Ucp4C Ucp4C http://flybase.org/reports/FBgn0031757 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 oxidative phosphorylation uncoupler activity ; GO:0017077 | inferred from sequence or structural similarity with UniProtKB:O95847 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR002067 response to cold ; GO:0009409 | inferred from biological aspect of ancestor with PANTHER:PTN001942541 mitochondrial transport ; GO:0006839 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 regulation of mitochondrial membrane potential ; GO:0051881 | inferred from biological aspect of ancestor with PANTHER:PTN001942541 proton transport ; GO:0015992 | inferred from sequence or structural similarity with UniProtKB:O95847 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with UniProtKB:O95847 "dmUCP4c, DmUCP4C, CG9064, anon-WO03061681.2, anon-WO03061681.1, anon-WO03037362.7, anon-WO0242455.4, anon-WO0242455.3, anon-WO02079478.2, anon-WO02079478.1, Ucp4C, Ucp4c, UCP4c, UCP4C, ucp4C" "IPR018108:Mitochondrial substrate/solute carrier, IPR002067:Mitochondrial carrier protein, IPR023395:Mitochondrial carrier domain" CG9064 27-Aug-18 DroID_v2018_08 "Drer\ucp1, Drer\ucp3, Drer\mrpl12, Drer\slc25a10, Drer\slc25a11, Drer\slc25a14, Drer\si:ch1073-100f3.2, Drer\slc25a27, Drer\ucp2" Scer\DIC1 "Cele\mrpl-12, Cele\slc-25A10, Cele\ucp-4" "Xtro\slc25a30, Xtro\slc25a10, Xtro\ucp2, Xtro\ucp1, Xtro\slc25a27, Xtro\rangrf" "Mmus\Mrpl12, Mmus\Ucp2, Mmus\Slc25a30, Mmus\Ucp3, Mmus\Slc25a27, Mmus\Slc25a10, Mmus\Slc25a14, Mmus\Ucp1, Mmus\Slc25a11" "Hsap\SLC25A10, Hsap\UCP1, Hsap\UCP3, Hsap\UCP2, Hsap\SLC25A14, Hsap\MRPL12, Hsap\SLC25A11, Hsap\SLC25A27, Hsap\SLC25A30" "viable,fertile" FBgn0065922 l(2)SH0153 lethal (2) SH0153 http://flybase.org/reports/FBgn0065922 gene - - - "l(2)SH0153, l(2)SH2 0153" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0260612 2L2468 - http://flybase.org/reports/FBgn0260612 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L2468 - - 27-Aug-18 DroID_v2018_08 - - - - - - viable "dorsal air sac primordium,somatic clone" FBgn0035141 Cypl Cyclophilin-like http://flybase.org/reports/FBgn0035141 protein_coding_gene "peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from electronic annotation with InterPro:IPR002130, InterPro:IPR020892, InterPro:IPR024936" "protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR002130, InterPro:IPR020892, InterPro:IPR024936 protein peptidyl-prolyl isomerization ; GO:0000413 | inferred from electronic annotation with InterPro:IPR002130 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay "CG13892, cypl, Cypl, cycl" "IPR002130:Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain, IPR024936:Cyclophilin-type peptidyl-prolyl cis-trans isomerase, IPR029000:Cyclophilin-like domain, IPR020892:Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site" CG13892 27-Aug-18 DroID_v2018_08 "Drer\ppil1, Drer\snx14" "Scer\CPR3, Scer\CPR5, Scer\CPR2" "Cele\snx-14, Cele\cyn-12, Cele\ZC250.5" "Xtro\snx14, Xtro\ppil1" Mmus\Ppil1 "Hsap\SNX14, Hsap\PPIL1" "viable,lethal" FBgn0061150 l(2)N113 lethal (2) N113 http://flybase.org/reports/FBgn0061150 gene - - - "N113, l(2)N113" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0052694 CG32694 - http://flybase.org/reports/FBgn0052694 protein_coding_gene - - lipid particle ; GO:0005811 | inferred from direct assay "CG18512, CG12649, CG12634, BcDNA:RE02049, CG32694" - CG32694 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,partially lethal - majority die,visible" mesothoracic tergum FBgn0011117 l(1)Q78 lethal (1) Q78 http://flybase.org/reports/FBgn0011117 FBgn0010210 gene - - - l(1)Q78 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0267276 asRNA:CR45712 - http://flybase.org/reports/FBgn0267276 non_protein_coding_gene - - - CR45712 - CR45712 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038385 Fbxl7 F-box and leucine-rich repeat protein 7 http://flybase.org/reports/FBgn0038385 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model "regulation of protein localization ; GO:0032880 | inferred from mutant phenotype cellular protein catabolic process ; GO:0044257 | inferred from mutant phenotype proximal/distal pattern formation, imaginal disc ; GO:0007449 | inferred from mutant phenotype regulation of hippo signaling ; GO:0035330 | inferred from mutant phenotype negative regulation of growth ; GO:0045926 | inferred from mutant phenotype negative regulation of imaginal disc growth ; GO:0045571 | inferred from mutant phenotype protein ubiquitination ; GO:0016567 | inferred from direct assay SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model" "SCF ubiquitin ligase complex ; GO:0019005 | inferred from physical interaction with Cul1, SkpA SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model cell-cell junction ; GO:0005911 | inferred from direct assay apical part of cell ; GO:0045177 | inferred from direct assay" "CG4221, FbxL7, FBXL7, Fbxl7, fbxl7" "IPR001810:F-box domain, IPR006553:Leucine-rich repeat, cysteine-containing subtype, IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like" CG4221 27-Aug-18 DroID_v2018_08 "Drer\usp43a, Drer\fbxl2, Drer\fbxl13, Drer\si:dkey-192l18.9, Drer\fbxl7, Drer\fbxl20, Drer\usp31, Drer\usp43b" "Scer\GRR1, Scer\RAD7, Scer\AMN1" Cele\fbxl-1 Xtro\fbxl7 "Mmus\Usp31, Mmus\Fbxl7, Mmus\Fbxl13, Mmus\Usp43, Mmus\Fbxl20, Mmus\Fbxl2" "Hsap\FBXL13, Hsap\USP31, Hsap\FBXL2, Hsap\USP43, Hsap\FBXL20, Hsap\FBXL7" "viable,fertile" FBgn0036945 Ssk Snakeskin http://flybase.org/reports/FBgn0036945 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:O46101 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q0KHY3 establishment of endothelial barrier ; GO:0061028 | inferred from mutant phenotype intestinal epithelial cell development ; GO:0060576 | inferred from mutant phenotype septate junction assembly ; GO:0019991 | inferred from mutant phenotype anterior midgut development ; GO:0007496 | inferred from mutant phenotype integral component of plasma membrane ; GO:0005887 | inferred from direct assay smooth septate junction ; GO:0005920 | inferred from direct assay "CT21613, ssk, Ssk, CG6981" - CG6981 27-Aug-18 DroID_v2018_08 - Scer\MPS3 "Cele\nhr-13, Cele\W03C9.2" - - - "viable,partially lethal - majority die,lethal,locomotor behavior defective" "anterior embryonic/larval midgut,smooth septate junctionda.G32" FBgn0035259 CG13932 - http://flybase.org/reports/FBgn0035259 protein_coding_gene - - - CG13932 - - 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0262356 CG43054 - http://flybase.org/reports/FBgn0262356 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43054, lincRNA.173" - CG43054 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0019695 l(2)k08601 lethal (2) k08601 http://flybase.org/reports/FBgn0019695 - gene - - - l(2)k08601 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" crystal cell FBgn0025921 l(3)78Ad lethal (3) 78Ad http://flybase.org/reports/FBgn0025921 - gene - - - l(3)78Ad - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0065453 l(2)SH1396 lethal (2) SH1396 http://flybase.org/reports/FBgn0065453 gene - - - "l(2)SH1396, l(2)SH2 1396" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0085750 CR40581 - http://flybase.org/reports/FBgn0085750 rRNA_gene - - - CR40581 - CR40581 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262791 CG43172 - http://flybase.org/reports/FBgn0262791 protein_coding_gene - - - "CG43172, noncoding_5744, nc_5744.a" - CG43172 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000204 bord bordered http://flybase.org/reports/FBgn0000204 - gene - - - bord - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,poor,visible,recessive" "wing,wing vein" FBgn0040688 CG12483 - http://flybase.org/reports/FBgn0040688 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RH38463, CG12483" - CG12483 27-Aug-18 DroID_v2018_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0051388 CG31388 - http://flybase.org/reports/FBgn0051388 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 "CG5135, CG17722, BcDNA:GH10523, CG31388" "IPR012934:Zinc finger, AD-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG31388 27-Aug-18 DroID_v2018_08 "Drer\znf1043, Drer\znf644a, Drer\zgc:173624, Drer\znf408, Drer\LOC101883642, Drer\LOC100537066, Drer\znf687a, Drer\LOC100149007, Drer\znf990, Drer\zgc:174696, Drer\znf1059, Drer\zbtb41, Drer\si:dkey-217d24.6, Drer\LOC100536649, Drer\znf1041, Drer\LOC103910931, Drer\si:ch211-194b1.1, Drer\LOC103910994, Drer\zgc:173705, Drer\znf569l, Drer\znf1073, Drer\zgc:174704, Drer\si:ch211-226o13.2, Drer\gb:am422109, Drer\si:ch211-162i8.2, Drer\LOC100538201, Drer\znf687b, Drer\znf407, Drer\zbtb17, Drer\zgc:173716, Drer\si:ch211-255f4.1, Drer\LOC100537431, Drer\mynn, Drer\LOC101882787, Drer\LOC108183429, Drer\LOC100535113, Drer\LOC100537572, Drer\LOC100534892, Drer\zbtb16b, Drer\si:dkeyp-104f11.6, Drer\prdm4, Drer\zgc:173714, Drer\znf1171, Drer\znf1147, Drer\znf1181, Drer\zgc:174703, Drer\zgc:174314, Drer\znf1053, Drer\LOC101885678, Drer\LOC100333857, Drer\znf1070, Drer\LOC108182424, Drer\LOC100333583, Drer\znf1177, Drer\si:dkeyp-35e5.9, Drer\LOC101885193, Drer\znf644b, Drer\znf507, Drer\znf995, Drer\LOC101882721, Drer\zbtb39, Drer\si:dkeyp-53d3.5, Drer\zgc:162948, Drer\si:dkeyp-35e5.10, Drer\si:dkey-20i20.2, Drer\znf1069, Drer\si:dkeyp-84f3.9, Drer\LOC100536900, Drer\si:dkey-30f3.2, Drer\znf1167, Drer\si:dkey-7i4.5, Drer\si:dkey-237m9.1, Drer\zgc:173713, Drer\LOC100537352, Drer\znf1077, Drer\znf1079, Drer\prdm2b, Drer\znf1068, Drer\znf1040, Drer\hnrnpa0l, Drer\si:ch211-223a21.4, Drer\zgc:113135, Drer\LOC100536312, Drer\zgc:174315, Drer\LOC100537450, Drer\LOC100537891, Drer\znf1173, Drer\si:dkey-1b17.5, Drer\znf1072, Drer\znf319, Drer\LOC100149645, Drer\znf592, Drer\si:dkey-262g12.7, Drer\znf1159, Drer\LOC108179202, Drer\prdm2a, Drer\LOC108184006, Drer\si:ch211-212k5.4, Drer\LOC101882607, Drer\si:ch211-255f4.3, Drer\LOC108183430, Drer\znf1078, Drer\LOC100536110, Drer\LOC100534765, Drer\LOC100150619, Drer\LOC569391, Drer\si:ch73-266f23.3, Drer\LOC100329723, Drer\LOC100332458" - "Cele\Y55F3AM.14, Cele\F58G1.2, Cele\eor-1, Cele\C27A12.2, Cele\M03D4.4, Cele\blmp-1, Cele\zfp-2" "Xtro\znf639, Xtro\znf91" "Mmus\4930522L14Rik, Mmus\Zfp866, Mmus\Zfp960, Mmus\Zfp872, Mmus\Prdm4, Mmus\Zbtb41, Mmus\Zfp984, Mmus\Zfp947, Mmus\Zfp445, Mmus\Rex2, Mmus\Zfp120, Mmus\Zfp991, Mmus\Mynn, Mmus\Zfp992, Mmus\Zfp995, Mmus\Zbtb17, Mmus\Zfp287, Mmus\Zfp697, Mmus\Zfp429, Mmus\Zfp768, Mmus\Zfp784, Mmus\Gzf1, Mmus\Zfp563, Mmus\Zfp646, Mmus\Zfp980, Mmus\Zfp985, Mmus\Zfp408, Mmus\Zfp932, Mmus\Zfp398, Mmus\Zfp592, Mmus\Zfp358, Mmus\Zfp426, Mmus\Zfp94, Mmus\Zfp109, Mmus\Zfp534, Mmus\AU041133, Mmus\Zfp870, Mmus\Zfp97, Mmus\Zfp93, Mmus\Rsl1, Mmus\Zfp57, Mmus\Zfp982, Mmus\Zfp407, Mmus\Gm20939, Mmus\Zfp777, Mmus\Zfp868, Mmus\Zfp944, Mmus\Zfp472, Mmus\Zfp687, Mmus\Zfp507, Mmus\Zfp626, Mmus\Zfp644, Mmus\Zfp943, Mmus\Zfp61, Mmus\Zfp114, Mmus\Zfp979, Mmus\Zfp758, Mmus\Gm4767, Mmus\Zfp597, Mmus\Zfp786, Mmus\Zfp108, Mmus\Prdm2, Mmus\Zbtb39, Mmus\Zfp462, Mmus\Zfp867, Mmus\Zfp946, Mmus\Zfp981, Mmus\Zfp942, Mmus\Gm10778, Mmus\Zkscan7, Mmus\Zfp820, Mmus\Zfp951, Mmus\Zfp871, Mmus\Zfp319, Mmus\Zfp746, Mmus\Zfp467, Mmus\Zfp987" "Hsap\ZNF445, Hsap\ZNF687, Hsap\ZNF527, Hsap\ZNF777, Hsap\ZNF697, Hsap\ZBTB17, Hsap\ZNF507, Hsap\ZNF467, Hsap\ZNF417, Hsap\ZNF426, Hsap\ZNF333, Hsap\ZNF462, Hsap\ZNF281, Hsap\ZNF547, Hsap\ZNF133, Hsap\ZNF806, Hsap\ZNF852, Hsap\ZNF784, Hsap\ZNF644, Hsap\ZNF768, Hsap\ZNF670, Hsap\ZNF230, Hsap\ZFP57, Hsap\ZNF234, Hsap\ZNF597, Hsap\ZNF786, Hsap\ZNF34, Hsap\ZNF407, Hsap\ZNF592, Hsap\MYNN, Hsap\ZNF287, Hsap\ZNF774, Hsap\ZNF746, Hsap\ZNF776, Hsap\ZKSCAN7, Hsap\PRDM2, Hsap\ZNF625, Hsap\ZNF416, Hsap\ZNF214, Hsap\ZNF582, Hsap\ZNF780A, Hsap\ZNF319, Hsap\ZNF251, Hsap\ZBTB41, Hsap\ZNF398, Hsap\ZNF530, Hsap\ZNF17, Hsap\ZNF566, Hsap\GZF1, Hsap\ZNF707, Hsap\PRDM4, Hsap\ZNF285, Hsap\ZBTB39, Hsap\ZNF408, Hsap\ZNF222, Hsap\ZNF136, Hsap\ZNF587, Hsap\ZNF223, Hsap\ZNF646, Hsap\ZNF155, Hsap\ZNF8" "viable,fertile" FBgn0015955 l(1)5ABa lethal (1) 5ABa http://flybase.org/reports/FBgn0015955 - gene - - - l(1)5ABa - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0044508 snoRNA:M snoRNA:M http://flybase.org/reports/FBgn0044508 snoRNA_gene - - - "CR32807, snoRNA:M" - CR32807 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051856 CG31856 - http://flybase.org/reports/FBgn0051856 protein_coding_gene - - - "BcDNA:SD21618, CG31856" - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible,lethal" mesothoracic tergum FBgn0000434 der deranged http://flybase.org/reports/FBgn0000434 - gene - - - der - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,female fertile,reduced,visible,recessive,female semi-sterile" "microchaeta & adult thorax,wing,macrochaeta & adult thorax" FBgn0032889 CG9331 - http://flybase.org/reports/FBgn0032889 protein_coding_gene "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor ; GO:0016616 | inferred from electronic annotation with InterPro:IPR006139 NAD binding ; GO:0051287 | inferred from electronic annotation with InterPro:IPR006139, InterPro:IPR006140" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006139, InterPro:IPR006140" extracellular region ; GO:0005576 | inferred from direct assay CG9331 "IPR006139:D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain, IPR006140:D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain, IPR016040:NAD(P)-binding domain, IPR029753:D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site" CG9331 27-Aug-18 DroID_v2018_08 "Drer\zgc:136493, Drer\grhprb, Drer\grhpra" "Scer\SER33, Scer\SER3, Scer\FDH1, Scer\YGL185C, Scer\YPL113C, Scer\GOR1" - "Xtro\grhpr.2, Xtro\grhpr.1" Mmus\Grhpr Hsap\GRHPR "viable,fertile" FBgn0023217 E(lz)53 E(lz)53 http://flybase.org/reports/FBgn0023217 - gene - - - E(lz)53 - - 27-Aug-18 DroID_v2018_08 - - - - - - wild-type FBgn0065256 l(2)SH2109 lethal (2) SH2109 http://flybase.org/reports/FBgn0065256 gene - - - "l(2)SH2109, l(2)SH2 2109" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0261819 CG42761 - http://flybase.org/reports/FBgn0261819 protein_coding_gene - - - CG42761 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004966 larv larvaphile http://flybase.org/reports/FBgn0004966 - gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "Lar, larv, lar" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,maternal effect" FBgn0001451 l(1)7De lethal (1) 7De http://flybase.org/reports/FBgn0001451 - gene - - - l(1)7De - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0011904 tRNA:Lys-TTT-2-4 transfer RNA:Lysine-TTT 2-4 http://flybase.org/reports/FBgn0011904 "FBgn0003793, FBgn0011901, FBgn0051486, FBgn0060176" tRNA_gene AAA codon-amino acid adaptor activity ; GO:0033443 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033443 cytosol ; GO:0005829 | inferred by curator from GO:0033443 "CR31486, lys5:84ABa, lys-tRNA-5, Lys-5, AE002699.trna4-LysTTT, tRNA:K5, tRNA:K:TTT:AE002699-a, tRNA:lys5:84AB, BG:DS00276.1, chr3R.trna77-LysTTT, tRNA-Lys-TTT-2-4, tRNA:Lys-TTT-2-4, tRNA:K5:84ABa, AAA" - CR31486 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0024911 anon-16Fa anon-16Fa http://flybase.org/reports/FBgn0024911 - gene - - - "F-b, anon-16Fa" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0027783 SMC2 Structural maintenance of chromosomes 2 http://flybase.org/reports/FBgn0027783 - protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR010935 ATPase activity ; GO:0016887 | inferred from sequence or structural similarity with SGD:S000001927 protein heterodimerization activity ; GO:0046982 | inferred from sequence or structural similarity with HGNC:14011 chromatin binding ; GO:0003682 | inferred from sequence or structural similarity with SGD:S000001927 neurogenesis ; GO:0022008 | inferred from mutant phenotype chromosome condensation ; GO:0030261 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype regulation of stem cell differentiation ; GO:2000736 | inferred from mutant phenotype condensin complex ; GO:0000796 | non-traceable author statement microtubule associated complex ; GO:0005875 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay chromatin ; GO:0000785 | inferred from direct assay condensin complex ; GO:0000796 | inferred from direct assay condensin complex ; GO:0000796 | inferred from sequence or structural similarity with HGNC:14011 condensed chromosome ; GO:0000793 | colocalizes_with inferred from direct assay "DmSMC2, CG10212, SMC2, AAF58197, dSMC2, smc-2, Smc2" "IPR003395:RecF/RecN/SMC, N-terminal, IPR010935:SMCs flexible hinge, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR024704:Structural maintenance of chromosomes protein" CG10212 27-Aug-18 DroID_v2018_08 "Drer\smc2, Drer\si:ch211-1o7.3" Scer\SMC2 "Cele\mix-1, Cele\spd-5" Xtro\smc2 Mmus\Smc2 Hsap\SMC2 "viable,fertile,enhancer of variegation,mitotic cell cycle defective,lethal - all die before end of larval stage,some die during larval stage,lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval brain,mitosis & nuclear chromosome,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0267795 Frl Formin-like http://flybase.org/reports/FBgn0267795 protein_coding_gene "actin binding ; GO:0003779 | inferred from electronic annotation with InterPro:IPR010472, InterPro:IPR010473 Rho GTPase binding ; GO:0017048 | inferred from electronic annotation with InterPro:IPR010473 actin binding ; GO:0003779 | inferred from sequence or structural similarity" actin cytoskeleton organization ; GO:0030036 | inferred from electronic annotation with InterPro:IPR010473 ommatidial rotation ; GO:0016318 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype axon extension ; GO:0048675 | inferred from genetic interaction with Cdc42 inferred from genetic interaction with DAAM cellular_component ; GO:0005575 | no biological data available "CG32138, Q9VUC6_DROME, Q9VUC5_DROME, CG6807, anon-WO0172774.98, CG13485, CG43986, Frl, frl" "IPR010472:Formin, FH3 domain, IPR014767:Diaphanous autoregulatory (DAD) domain, IPR014768:Rho GTPase-binding/formin homology 3 (GBD/FH3) domain, IPR015425:Formin, FH2 domain, IPR010473:Formin, GTPase-binding domain, IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical" CG32138 27-Aug-18 DroID_v2018_08 "Drer\fmnl2b, Drer\fmnl1b, Drer\fmnl1a, Drer\inf2, Drer\fmnl2a, Drer\daam1b, Drer\fhdc4, Drer\grid2ipb, Drer\fmnl3" "Scer\BNR1, Scer\BNI1" "Cele\frl-1, Cele\exc-6, Cele\fozi-1, Cele\cyk-1, Cele\daam-1" "Xtro\fmnl1, Xtro\inf2, Xtro\fmnl2" "Mmus\Fmnl1, Mmus\Daam1, Mmus\Diaph3, Mmus\Fmnl3, Mmus\Grid2ip, Mmus\Inf2, Mmus\Fmnl2, Mmus\Diaph1, Mmus\Daam2, Mmus\Diaph2" "Hsap\DIAPH2, Hsap\GRID2IP, Hsap\INF2, Hsap\FMNL1, Hsap\DIAPH3, Hsap\FMNL2, Hsap\DIAPH1, Hsap\FMNL3, Hsap\DAAM2, Hsap\DAAM1" FBgn0038436 Gyc89Db Guanylyl cyclase at 89Db http://flybase.org/reports/FBgn0038436 protein_coding_gene heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR011644 protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with UniProtKB:Q8INF0 guanylate cyclase activity ; GO:0004383 | inferred from direct assay guanylate cyclase activity ; GO:0004383 | contributes_to inferred from direct assay "intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR001054, InterPro:IPR018297 response to reactive oxygen species ; GO:0000302 | inferred from direct assay cGMP biosynthetic process ; GO:0006182 | inferred from direct assay response to hyperoxia ; GO:0055093 | inferred from mutant phenotype signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 response to hypoxia ; GO:0001666 | inferred from mutant phenotype" "guanylate cyclase complex, soluble ; GO:0008074 | inferred from direct assay guanylate cyclase complex, soluble ; GO:0008074 | inferred from sequence or structural similarity guanylate cyclase complex, soluble ; GO:0008074 | inferred by curator from GO:0004383 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000228924" "CG14886, Gyc-89Db, Gyc89Db" "IPR018297:Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR001054:Adenylyl cyclase class-3/4/guanylyl cyclase, IPR011644:Heme-NO binding, IPR024096:NO signalling/Golgi transport ligand-binding domain, IPR029787:Nucleotide cyclase, IPR011645:Haem NO binding associated" CG14886 27-Aug-18 DroID_v2018_08 "Drer\gucy1b3, Drer\gucy1a2, Drer\gucy1b2, Drer\gucy1a3" - "Cele\gcy-36, Cele\gcy-31, Cele\gcy-34, Cele\gcy-35, Cele\gcy-33, Cele\gcy-37, Cele\gcy-32" "Xtro\gucy1b3, Xtro\gucy1a2" "Mmus\Gucy1a2, Mmus\Gucy1a3, Mmus\Gucy1b2, Mmus\Gucy1b3" "Hsap\GUCY1B3, Hsap\GUCY1A3, Hsap\GUCY1A2" "stress response defective,taste perception defective,viable,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0024920 Ts Thymidylate synthase http://flybase.org/reports/FBgn0024920 - protein_coding_gene "thymidylate synthase activity ; GO:0004799 | inferred from electronic annotation with InterPro:IPR000398, InterPro:IPR020940" "dTMP biosynthetic process ; GO:0006231 | inferred from electronic annotation with InterPro:IPR000398, InterPro:IPR020940 neurogenesis ; GO:0022008 | inferred from mutant phenotype" - "CG3181, FBgn0024920, TS, c1.5, anon-23Ca, Ts" "IPR000398:Thymidylate synthase, IPR023451:Thymidylate synthase/dCMP hydroxymethylase domain, IPR020940:Thymidylate synthase, active site" CG3181 27-Aug-18 DroID_v2018_08 Drer\tyms Scer\CDC21 Cele\tyms-1 Xtro\tyms Mmus\Tyms Hsap\TYMS "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,trichogen cell" FBgn0005153 l(2)G94 lethal (2) G94 http://flybase.org/reports/FBgn0005153 - gene - - - l(2)G94 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0032208 Ufd4 Ubiquitin fusion-degradation 4-like http://flybase.org/reports/FBgn0032208 protein_coding_gene metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR010606 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:12306 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from sequence or structural similarity with HGNC:12306 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:12306 "CG5604, Ufd4" "IPR000569:HECT domain, IPR002110:Ankyrin repeat, IPR010606:Mib-herc2, IPR012919:SUN domain, IPR008979:Galactose-binding domain-like, IPR016024:Armadillo-type fold, IPR020683:Ankyrin repeat-containing domain, IPR011989:Armadillo-like helical" CG5604 27-Aug-18 DroID_v2018_08 "Drer\hectd1, Drer\trip12" Scer\UFD4 Cele\hecd-1 "Xtro\trip12, Xtro\hectd1" "Mmus\Hectd1, Mmus\Trip12" "Hsap\HECTD1, Hsap\TRIP12" "viable,visible" mesothoracic tergum FBgn0086690 Plp Pericentrin-like protein http://flybase.org/reports/FBgn0086690 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Sas-4 sensory perception of sound ; GO:0007605 | inferred from mutant phenotype embryonic morphogenesis ; GO:0048598 | inferred from mutant phenotype microtubule nucleation ; GO:0007020 | inferred from direct assay centrosome organization ; GO:0051297 | inferred from mutant phenotype cilium-dependent cell motility ; GO:0060285 | inferred from mutant phenotype centriole ; GO:0005814 | inferred from direct assay "Plp, D-PLP, CG6735, CG18648, CG13459, d-plp, CP309, AKAP450, l(3)s2172, CG33957, cp309, PACT, dplp, DPLP, pPlp, PLP, Cp309, dPLP, Dplp, plp" IPR019528:Pericentrin/AKAP-450 centrosomal targeting domain CG33957 27-Aug-18 DroID_v2018_08 "Drer\akap9, Drer\pcnt" Scer\SLK19 "Cele\C18C4.5, Cele\hcp-1" - "Mmus\Akap9, Mmus\Pcnt" "Hsap\PCNT, Hsap\AKAP9" FBgn0262486 CG43076 - http://flybase.org/reports/FBgn0262486 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43076, lincRNA.997" - CG43076 27-Aug-18 DroID_v2018_08 Drer\tmem101 - - Xtro\tmem101 Mmus\Tmem101 Hsap\TMEM101 FBgn0011129 l(1)Q203 lethal (1) Q203 http://flybase.org/reports/FBgn0011129 FBgn0010210 gene - - - l(1)Q203 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0011954 tRNA:Arg-TCG-2-2 transfer RNA:Arginine-TCG 2-2 http://flybase.org/reports/FBgn0011954 "FBgn0011947, FBgn0052526, FBgn0060078" tRNA_gene CGA codon-amino acid adaptor activity ; GO:0033431 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033431 cytosol ; GO:0005829 | inferred by curator from GO:0033431 "CR32526, tRNA-Arg, tRNA[arg], AE002620.trna3-ArgTCG, tRNA:R1, tRNA:arg1, tRNA:R:TCG:AE002620, tRNA:arg19F, chrX.trna16-ArgTCG, tRNA-Arg-TCG-2-2, tRNA:Arg-TCG-2-2, tRNA:R:19F, CGA" - CR32526 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0052282 Drsl4 Drosomycin-like 4 http://flybase.org/reports/FBgn0052282 protein_coding_gene molecular_function ; GO:0003674 | no biological data available defense response to fungus ; GO:0050832 | inferred from direct assay defense response to fungus ; GO:0050832 | inferred from sequence or structural similarity with Drs extracellular region ; GO:0005576 | inferred from sequence or structural similarity with Drs inferred from sequence model "Dro4, Dro-4, CG32282, Drs-lF, dros4, dro4, dro-4, Drsl4" "IPR003614:Knottin, scorpion toxin-like" CG32282 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0026573 ADD1 ADD domain-containing protein 1 http://flybase.org/reports/FBgn0026573 FBgn0033670 protein_coding_gene chromatin DNA binding ; GO:0031490 | inferred from direct assay methylated histone binding ; GO:0035064 | inferred from physical interaction with His3 protein binding ; GO:0005515 | inferred from physical interaction with Su(var)205 inferred from physical interaction with Su(var)205 inferred from physical interaction with Su(var)205 inferred from physical interaction with Su(var)205 inferred from physical interaction with Su(var)205 heterochromatin organization involved in chromatin silencing ; GO:0070868 | inferred from mutant phenotype polytene chromosome chromocenter ; GO:0005701 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay heterochromatin ; GO:0000792 | inferred from direct assay polytene chromosome interband ; GO:0005705 | inferred from direct assay polytene chromosome band ; GO:0005704 | inferred from direct assay pericentric heterochromatin ; GO:0005721 | inferred from direct assay "LD29214, BEST:LD29214, CG8290, ADD1, dADD1, dadd1" "IPR025766:ADD domain, IPR006578:MADF domain, IPR011011:Zinc finger, FYVE/PHD-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG8290 27-Aug-18 DroID_v2018_08 "Drer\dnmt3bb.3, Drer\dnmt3ab, Drer\dnmt3bb.1, Drer\dnmt3bb.2, Drer\dnmt3aa, Drer\dnmt3ba, Drer\atrx" - Cele\xnp-1 Xtro\dnmt3a "Mmus\Atrx, Mmus\Dnmt3a, Mmus\Dnmt3b, Mmus\Dnmt3l" "Hsap\DNMT3A, Hsap\DNMT3L, Hsap\ATRX, Hsap\DNMT3B" "viable,suppressor of variegation,dominant,lethal" FBgn0065732 l(2)SH0551 lethal (2) SH0551 http://flybase.org/reports/FBgn0065732 gene - - - l(2)SH0551 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0063648 CE2-1 "Calcineurin enhancer, chromosome 2, group 1" http://flybase.org/reports/FBgn0063648 gene - - - CE2-1 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0001538 l(1)14Cb lethal (1) 14Cb http://flybase.org/reports/FBgn0001538 - gene - - - "l(1)k17a, k17a, l(1)14Cb" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0016945 tilA touch insensitive larva A http://flybase.org/reports/FBgn0016945 - gene - - - tilA - - 27-Aug-18 DroID_v2018_08 - - - - - - "touch sensitivity defective,recessive,behavior defective" FBgn0060561 l(3)S096805a lethal (3) S096805a http://flybase.org/reports/FBgn0060561 gene - - - "0968/05, l(3)S096805a" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0052984 CG32984 - http://flybase.org/reports/FBgn0052984 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR017849, InterPro:IPR017850" "metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR017849, InterPro:IPR017850" - "CG17789, CG32984, gi21430910, gi22945998" "IPR004245:Protein of unknown function DUF229, IPR017850:Alkaline-phosphatase-like, core domain, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha" CG32984 27-Aug-18 DroID_v2018_08 - - "Cele\T07G12.3, Cele\Y38A10A.2, Cele\Y41E3.1, Cele\T23E1.1, Cele\F07C3.3, Cele\R03G8.1, Cele\F15H10.7, Cele\F10C2.3, Cele\F32G8.2, Cele\R03G8.3, Cele\K03A11.4, Cele\Y73F8A.35, Cele\F32D8.2, Cele\M03F8.5" - - - viable FBgn0029946 CG15034 - http://flybase.org/reports/FBgn0029946 protein_coding_gene - - - CG15034 - CG15034 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0001280 janA janus A http://flybase.org/reports/FBgn0001280 FBgn0063739 protein_coding_gene phosphohistidine phosphatase activity ; GO:0008969 | inferred from biological aspect of ancestor with PANTHER:PTN000262360 sex differentiation ; GO:0007548 | inferred from expression pattern peptidyl-histidine dephosphorylation ; GO:0035971 | inferred from biological aspect of ancestor with PANTHER:PTN000262360 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000262360 "janus, jan, jan A, Jan, Y, BcDNA:AT12574, CG7933, janA" IPR007702:Janus CG7933 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-51e6.1, Drer\phpt1" - Cele\phip-1 Xtro\phpt1 Mmus\Phpt1 Hsap\PHPT1 " adult stage | male , embryonic stage -- adult stage , larval stage--adult stage | male " organism

viable FBgn0039068 CG13827 - http://flybase.org/reports/FBgn0039068 protein_coding_gene - peroxisome fission ; GO:0016559 | inferred from electronic annotation with InterPro:IPR008733 lateral inhibition ; GO:0046331 | inferred from mutant phenotype integral component of peroxisomal membrane ; GO:0005779 | inferred from electronic annotation with InterPro:IPR008733 peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:20208 "BcDNA:RE30473, CG13827, PEX11C" "IPR008733:Peroxisomal biogenesis factor 11, IPR026510:Peroxisomal membrane protein 11C, metazoa" CG13827 27-Aug-18 DroID_v2018_08 "Drer\pex11a, Drer\pex11g, Drer\pex11b" Scer\PEX11 Cele\prx-11 "Xtro\pex11b, Xtro\pex11a, Xtro\pex11g" "Mmus\Pex11g, Mmus\Pex11a, Mmus\Pex11b" "Hsap\PEX11G, Hsap\PEX11B, Hsap\PEX11A" "viable,visible" chaeta FBgn0004240 DptA Diptericin A http://flybase.org/reports/FBgn0004240 - protein_coding_gene - defense response to bacterium ; GO:0042742 | inferred from sequence or structural similarity antibacterial humoral response ; GO:0019731 | inferred from expression pattern response to hyperoxia ; GO:0055093 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype response to bacterium ; GO:0009617 | inferred from direct assay defense response to bacterium ; GO:0042742 | non-traceable author statement positive regulation of innate immune response ; GO:0045089 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from expression pattern innate immune response ; GO:0045087 | non-traceable author statement response to bacterium ; GO:0009617 | inferred from expression pattern defense response to bacterium ; GO:0042742 | traceable author statement - "dipt, Dpt, Dipt, 143443_at, DPT, DIPT, DptA, Dip, dpt, CG12763, dip, Dep, DiptA, DIM 27, Dit, diptA" - CG12763 27-Aug-18 DroID_v2018_08 - - - - - - "viable,lethal,partially lethal - majority die,visible" "adult posterior midgut epithelium,mesothoracic tergum" FBgn0065468 l(2)SH1337 lethal (2) SH1337 http://flybase.org/reports/FBgn0065468 gene - - - "l(2)SH1337, l(2)SH2 1337" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0004939 ABO-YS Abnormal Oocyte on YS http://flybase.org/reports/FBgn0004939 - region - - - "ABO, ABO-YS" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266865 asRNA:CR45326 - http://flybase.org/reports/FBgn0266865 non_protein_coding_gene - - - CR45326 - CR45326 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262481 CG43071 - http://flybase.org/reports/FBgn0262481 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43071, lincRNA.347" - CG43071 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0053236 Ste:CG33236 Ste:CG33236 http://flybase.org/reports/FBgn0053236 protein_coding_gene protein kinase regulator activity ; GO:0019887 | inferred from mutant phenotype regulation of protein serine/threonine phosphatase activity ; GO:0080163 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay protein kinase CK2 complex ; GO:0005956 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG32605, CG33236, Ste:CG33236" "IPR000704:Casein kinase II, regulatory subunit, IPR016149:Casein kinase II, regulatory subunit, alpha-helical" CG33236 27-Aug-18 DroID_v2018_08 Drer\csnk2b "Scer\CKB1, Scer\CKB2" Cele\kin-10 Xtro\csnk2b Mmus\Csnk2b Hsap\CSNK2B FBgn0028604 l(2)W3 lethal (2) W3 http://flybase.org/reports/FBgn0028604 gene - - - "l(2R)W3, l(2)W3" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0008653 mn manikin http://flybase.org/reports/FBgn0008653 - gene - - - mn - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,male sterile,viable,male,poor" "adult abdomen,adult thorax" FBgn0060976 l(3)S028830 lethal (3) S028830 http://flybase.org/reports/FBgn0060976 gene - - - "0288/30, l(3)S028830" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal" FBgn0259392 C708 - http://flybase.org/reports/FBgn0259392 gene - - - C708 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing vein,wing margin,chaeta,ectopic" FBgn0010009 Amr Amanatin resistant http://flybase.org/reports/FBgn0010009 - gene - - - Amr - - 27-Aug-18 DroID_v2018_08 - - - - - - "chemical resistant,dominant" FBgn0266961 lncRNA:CR45412 - http://flybase.org/reports/FBgn0266961 non_protein_coding_gene - - - CR45412 - CR45412 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0016667 Hrp62 Hrp62 http://flybase.org/reports/FBgn0016667 - gene single-stranded DNA binding ; GO:0003697 | inferred from direct assay biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "hrp62, Hrp62" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0028982 Spt6 Spt6 http://flybase.org/reports/FBgn0028982 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR028088 chromatin binding ; GO:0003682 | inferred from direct assay nucleosome binding ; GO:0031491 | inferred from biological aspect of ancestor with PANTHER:PTN000015765 transcription factor activity, core RNA polymerase II binding ; GO:0000991 | inferred from biological aspect of ancestor with PANTHER:PTN000015765 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN000015765 histone binding ; GO:0042393 | inferred from biological aspect of ancestor with PANTHER:PTN000015765" regulation of mRNA processing ; GO:0050684 | inferred from biological aspect of ancestor with PANTHER:PTN000015765 positive regulation of transcription elongation from RNA polymerase II promoter ; GO:0032968 | inferred from mutant phenotype chromatin maintenance ; GO:0070827 | inferred from biological aspect of ancestor with PANTHER:PTN000015765 transcription from RNA polymerase II promoter ; GO:0006366 | inferred from expression pattern regulation of antimicrobial peptide biosynthetic process ; GO:0002805 | inferred from mutant phenotype chromatin silencing ; GO:0006342 | inferred from biological aspect of ancestor with PANTHER:PTN000015765 nucleosome organization ; GO:0034728 | inferred from biological aspect of ancestor with PANTHER:PTN000015765 mRNA transcription from RNA polymerase II promoter ; GO:0042789 | inferred from biological aspect of ancestor with PANTHER:PTN000015765 ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay transcription elongation factor complex ; GO:0008023 | inferred from physical interaction with UniProtKB:Q9V460 polytene chromosome puff ; GO:0005703 | inferred from direct assay transcriptionally active chromatin ; GO:0035327 | inferred from direct assay histone locus body ; GO:0035363 | inferred from direct assay polytene chromosome interband ; GO:0005705 | inferred from direct assay FACT complex ; GO:0035101 | colocalizes_with inferred from physical interaction with UniProtKB:Q05344 nuclear exosome (RNase complex) ; GO:0000176 | colocalizes_with inferred from direct assay "Spt6, Dspt6, dSpt6, spt 6, CG12225, SPT6, l(1)G0063, spt6, dspt6" "IPR000980:SH2 domain, IPR003029:S1 domain, IPR006641:YqgF/RNase H-like domain, IPR012340:Nucleic acid-binding, OB-fold, IPR017072:Transcription elongation factor Spt6, IPR023323:Tex-like domain, IPR032706:Transcription elongation factor Spt6, helix-hairpin-helix motif, IPR012337:Ribonuclease H-like domain, IPR010994:RuvA domain 2-like, IPR023319:Tex-like protein, HTH domain, IPR028088:Helix-turn-helix DNA-binding domain of Spt6, IPR027999:Death-like domain of Spt6, IPR028083:Spt6 acidic, N-terminal domain, IPR028231:Transcription elongation factor Spt6, YqgF domain, IPR022967:RNA-binding domain, S1" CG12225 27-Aug-18 DroID_v2018_08 Drer\supt6h Scer\SPT6 Cele\emb-5 Xtro\supt6h Mmus\Supt6 Hsap\SUPT6H "viable,lethal - all die before end of embryonic stage,lethal,recessive,some die during embryonic stage,melanotic mass phenotype,visible,lethal - all die before end of larval stage,some die during larval stage" "female germline cell,cuticle | pharate adult stage,abdomen | pharate adult stage,trichome | pharate adult stage,melanotic mass | pharate adult stage" DRSC18836 IEK -1.50883966 3.049083373 -0.259982998 1.840579737 2.792518087 2.602204713 FBgn0031465 CG3123 - http://flybase.org/reports/FBgn0031465 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR017849, InterPro:IPR017850" "metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR017849, InterPro:IPR017850" - "CG3123, gi7295901, gi21064005" "IPR017850:Alkaline-phosphatase-like, core domain, IPR004245:Protein of unknown function DUF229, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha" CG3123 27-Aug-18 DroID_v2018_08 - - "Cele\R03G8.3, Cele\M03F8.5, Cele\Y73F8A.35, Cele\Y38A10A.2, Cele\T07G12.3, Cele\K03A11.4, Cele\T23E1.1, Cele\F15H10.7, Cele\R03G8.1, Cele\F32G8.2, Cele\Y41E3.1, Cele\F10C2.3, Cele\F32D8.2, Cele\F07C3.3" - - - viable FBgn0262816 CG43187 - http://flybase.org/reports/FBgn0262816 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43187, DMG8-chr2R.23.004, lincRNA.322" - CG43187 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0029745 Rpn13R Regulatory particle non-ATPase 13-related http://flybase.org/reports/FBgn0029745 protein_coding_gene endopeptidase activator activity ; GO:0061133 | inferred from biological aspect of ancestor with PANTHER:PTN000259827 ubiquitin binding ; GO:0043130 | inferred from biological aspect of ancestor with PANTHER:PTN000259827 proteasome binding ; GO:0070628 | inferred from biological aspect of ancestor with PANTHER:PTN000259827 ubiquitin binding ; GO:0043130 | inferred from sequence or structural similarity with SGD:S000004413 ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from sequence or structural similarity with SGD:S000004413 ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from biological aspect of ancestor with PANTHER:PTN000259827 "cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR006773 nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR006773 proteasome regulatory particle, lid subcomplex ; GO:0008541 | inferred from sequence or structural similarity with SGD:S000004413 proteasome regulatory particle, lid subcomplex ; GO:0008541 | inferred from biological aspect of ancestor with PANTHER:PTN000259827" "CG6789, Rpn13R" "IPR006773:26S proteasome complex ubiquitin receptor, subunit Rpn13, IPR032368:UCH-binding domain" CG6789 27-Aug-18 DroID_v2018_08 Drer\adrm1 Scer\RPN13 Cele\rpn-13 Xtro\adrm1 Mmus\Adrm1 Hsap\ADRM1 "viable,visible" trichogen cell FBgn0267748 lncRNA:CR46079 - http://flybase.org/reports/FBgn0267748 non_protein_coding_gene - - - CR46079 - CR46079 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002139 l(2)K300 lethal (2) K300 http://flybase.org/reports/FBgn0002139 - gene - - - l(2)K300 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0053448 5SrRNA:CR33448 5SrRNA:CR33448 http://flybase.org/reports/FBgn0053448 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33448, 5SrRNA:CR33448" - CR33448 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0019849 anon-XV anon-XV http://flybase.org/reports/FBgn0019849 - gene - - - "XV, anon-XV" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262551 Mod(GMroX1)143 - http://flybase.org/reports/FBgn0262551 gene - - - Mod(GMroX1)143 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260658 CG42541 - http://flybase.org/reports/FBgn0260658 protein_coding_gene "GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR001806 GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR020849" signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR020849 phagocytosis ; GO:0006909 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR020849 "CG42541, CG15240, CG16828, CG16829, BcDNA:RH43809, CG32776" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR001806:Small GTPase superfamily, IPR020849:Small GTPase superfamily, Ras type, IPR015943:WD40/YVTN repeat-like-containing domain" CG42541 27-Aug-18 DroID_v2018_08 "Drer\hrasb, Drer\rap2ab, Drer\ralaa, Drer\diras1b, Drer\nras, Drer\si:dkeyp-59c12.1, Drer\rhebl1, Drer\rasl11b, Drer\rem1, Drer\rap1aa, Drer\rras2, Drer\ralbb, Drer\diras1a, Drer\si:dkey-27j5.5, Drer\rrad, Drer\zgc:114118, Drer\rergla, Drer\si:ch73-116o1.2, Drer\zgc:152698, Drer\rheb, Drer\zgc:153845, Drer\rasd1, Drer\rem2, Drer\gem, Drer\LOC100332969, Drer\kras, Drer\hrasa, Drer\zgc:110699, Drer\zgc:64022, Drer\rras, Drer\rsg1, Drer\ralab, Drer\rit1, Drer\rap1ab, Drer\rap2b, Drer\ralba, Drer\zgc:171704, Drer\rap2c, Drer\rasl12, Drer\mras, Drer\diras2, Drer\rasl10a, Drer\rerglb, Drer\rasl11a" "Scer\RAS1, Scer\RHB1, Scer\RAS2, Scer\RSR1" Cele\Y52B11A.4 "Xtro\ras-dva, Xtro\ralb, Xtro\rasl10a, Xtro\rap2b, Xtro\rhebl1, Xtro\hras, Xtro\rap1b, Xtro\rala, Xtro\rasl11b, Xtro\diras2, Xtro\nras, Xtro\LOC733456, Xtro\rerg, Xtro\rap2a, Xtro\rasd1, Xtro\gem, Xtro\kras, Xtro\rit1, Xtro\rem1, Xtro\diras3, Xtro\rasd2, Xtro\rheb, Xtro\rem2, Xtro\rergl, Xtro\diras1, Xtro\rap2c, Xtro\rap1a, Xtro\rrad, Xtro\rsg1" "Mmus\Rerg, Mmus\Rasl11a, Mmus\Diras1, Mmus\Kras, Mmus\Gem, Mmus\Gm266, Mmus\Rasl12, Mmus\Rasl11b, Mmus\Rap2b, Mmus\Rasd1, Mmus\Rap2a, Mmus\Nras, Mmus\Rap1a, Mmus\Mras, Mmus\Eras, Mmus\Ralb, Mmus\Rit1, Mmus\Rras2, Mmus\Rsg1, Mmus\Hras, Mmus\Rit2, Mmus\Rem2, Mmus\Rasl10a, Mmus\Rrad, Mmus\Rap2c, Mmus\Rap1b, Mmus\Rergl, Mmus\Rem1, Mmus\Diras2, Mmus\Rasl10b, Mmus\Rheb, Mmus\Rhebl1, Mmus\Rras, Mmus\Rala, Mmus\Rasd2" "Hsap\RHEBL1, Hsap\RIT1, Hsap\RASD1, Hsap\RASL11A, Hsap\NRAS, Hsap\DIRAS2, Hsap\RAP2B, Hsap\RAP2C, Hsap\DIRAS3, Hsap\HRAS, Hsap\ERAS, Hsap\REM1, Hsap\RHEB, Hsap\RERG, Hsap\RRAS, Hsap\GEM, Hsap\RIT2, Hsap\KRAS, Hsap\REM2, Hsap\RAP2A, Hsap\RASL11B, Hsap\RAP1A, Hsap\RASD2, Hsap\RALA, Hsap\RRAS2, Hsap\RALB, Hsap\RASL12, Hsap\RASL10A, Hsap\MRAS, Hsap\RRAD, Hsap\DIRAS1, Hsap\RERGL, Hsap\RASL10B, Hsap\RAP1B, Hsap\RSG1" FBgn0004970 l(1)4Ea lethal (1) 4Ea http://flybase.org/reports/FBgn0004970 - gene - - - l(1)4Ea - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0267635 lncRNA:CR45973 - http://flybase.org/reports/FBgn0267635 non_protein_coding_gene - - - CR45973 - CR45973 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0010385 Def Defensin http://flybase.org/reports/FBgn0010385 - protein_coding_gene - antibacterial humoral response ; GO:0019731 | inferred from sequence or structural similarity inferred from expression pattern defense response to Gram-positive bacterium ; GO:0050830 | inferred from direct assay defense response to Gram-positive bacterium ; GO:0050830 | inferred from expression pattern defense response to Gram-positive bacterium ; GO:0050830 | traceable author statement defense response to bacterium ; GO:0042742 | traceable author statement response to bacterium ; GO:0009617 | inferred from expression pattern humoral immune response ; GO:0006959 | inferred from expression pattern defense response to bacterium ; GO:0042742 | non-traceable author statement response to bacterium ; GO:0009617 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay "Def, Defensin, 143607_at, CG1385, def, DEF, DIM 26, defensin, Dfn" "IPR001542:Defensin, invertebrate/fungal, IPR003614:Knottin, scorpion toxin-like" CG1385 27-Aug-18 DroID_v2018_08 - - - - - - " larval stage , adult stage " " embryonic/larval fat body

, adult fat body

" viable FBgn0267108 CR45548 - http://flybase.org/reports/FBgn0267108 pseudogene_attribute - - - CR45548 - CR45548 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0010118 l(1)16Fe lethal (1) 16Fe http://flybase.org/reports/FBgn0010118 - gene - - - "HL-VI, l(1)16Fe" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,polyphasic,recessive,neurophysiology defective" "wing,leg,adult somatic muscle" FBgn0053556 form3 formin 3 http://flybase.org/reports/FBgn0053556 protein_coding_gene actin binding ; GO:0003779 | inferred from electronic annotation with InterPro:IPR010472 actin binding ; GO:0003779 | inferred from sequence or structural similarity "cellular component organization ; GO:0016043 | inferred from electronic annotation with InterPro:IPR010472 branch fusion, open tracheal system ; GO:0035147 | inferred from mutant phenotype" - "formin/DIA-like, CG18138, CG8633, CG14824, ah1644, CG32384, CG33556, form3, Form3, INF2" "IPR010472:Formin, FH3 domain, IPR014768:Rho GTPase-binding/formin homology 3 (GBD/FH3) domain, IPR015425:Formin, FH2 domain, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold" CG33556 27-Aug-18 DroID_v2018_08 "Drer\fmnl2a, Drer\fmn2a, Drer\fhdc3, Drer\fmn2b, Drer\daam1a, Drer\grid2ipb, Drer\inf2, Drer\fhdc4, Drer\grid2ipa, Drer\fmn1, Drer\LOC100148950, Drer\fhdc1, Drer\daam2, Drer\fhdc2, Drer\daam1b" "Scer\BNR1, Scer\BNI1" "Cele\cyk-1, Cele\frl-1, Cele\inft-2, Cele\daam-1, Cele\exc-6" "Xtro\fmn1, Xtro\inf2, Xtro\daam1, Xtro\fhdc1, Xtro\fmnl1, Xtro\grid2ip" "Mmus\Diaph1, Mmus\Fmnl1, Mmus\Diaph2, Mmus\Daam1, Mmus\Daam2, Mmus\Fmnl2, Mmus\Fmnl3, Mmus\Fmn1, Mmus\Diaph3, Mmus\Inf2, Mmus\Fhdc1, Mmus\Grid2ip" "Hsap\FAM47A, Hsap\INF2, Hsap\DAAM2, Hsap\FMNL1, Hsap\DIAPH2, Hsap\FMNL2, Hsap\FMN1, Hsap\DAAM1, Hsap\FMNL3, Hsap\FAM47B, Hsap\DIAPH1, Hsap\GRID2IP, Hsap\FHDC1, Hsap\FAM47C, Hsap\DIAPH3" "lethal,viable,recessive,neuroanatomy defective,oxidative stress response defective,fertile" "presumptive embryonic/larval tracheal system,embryonic/larval dorsal trunk,dorsal trunk primordium,ventral nerve cord commissure,longitudinal connective,ventral nerve cord" FBgn0022315 l(1)D39.5 lethal (1) D39.5 http://flybase.org/reports/FBgn0022315 - gene - - - "D39.5, l(1)D39.5" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0019763 l(1)6c-21 lethal (1) 6c-21 http://flybase.org/reports/FBgn0019763 - gene - - - l(1)6c-21 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0067622 LSm-4 Like Sm protein 4 http://flybase.org/reports/FBgn0067622 protein_coding_gene - "regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype" - "CG31990, BcDNA:SD20015, CG31990-ORFA, CG33677, LSm-4, LSm4, LSM4" IPR017920:COMM domain CG33677 27-Aug-18 DroID_v2018_08 "Drer\commd5, Drer\commd9" - Cele\T07C4.12 "Xtro\commd5, Xtro\commd9" "Mmus\Commd9, Mmus\Commd5" "Hsap\COMMD5, Hsap\COMMD9" FBgn0030098 CG12057 - http://flybase.org/reports/FBgn0030098 protein_coding_gene - - - "BcDNA:LP05863, CG12057" IPR007931:Protein of unknown function DUF725 CG12057 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0033229 CG12822 - http://flybase.org/reports/FBgn0033229 protein_coding_gene - - - "CG12822, CG12822-PA" IPR023370:TsaA-like domain CG12822 27-Aug-18 DroID_v2018_08 "Drer\zgc:66475, Drer\trmo" - - Xtro\trmo Mmus\Trmo Hsap\TRMO viable FBgn0084555 bda belinda http://flybase.org/reports/FBgn0084555 gene - - - bda - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0261822 Bsg Basigin http://flybase.org/reports/FBgn0261822 protein_coding_gene - single organismal cell-cell adhesion ; GO:0016337 | inferred from mutant phenotype endoplasmic reticulum localization ; GO:0051643 | inferred from mutant phenotype spermatid development ; GO:0007286 | inferred from mutant phenotype photoreceptor cell morphogenesis ; GO:0008594 | inferred from mutant phenotype sarcomere organization ; GO:0045214 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype nucleus localization ; GO:0051647 | inferred from mutant phenotype mitochondrion localization ; GO:0051646 | inferred from mutant phenotype cytoskeleton of presynaptic active zone ; GO:0048788 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay presynaptic active zone ; GO:0048786 | inferred from mutant phenotype "Bsg, NP6293, bsg, CG31605, gel, 135/10, l(2)06243, l(2)k13638, l(2)k09030, l(2)k06338, ms(2)08318, BcDNA:GH21853, l(2)k14308, l(2)SH1217, l(2)SH2 1217" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold" CG31605 27-Aug-18 DroID_v2018_08 "Drer\vstm2l, Drer\bsg, Drer\nptnb, Drer\nptna, Drer\si:ch211-261c8.5" - "Cele\zig-1, Cele\zig-7, Cele\zig-11" "Xtro\bsg, Xtro\nptn, Xtro\emb" "Mmus\Bsg, Mmus\Vstm2l, Mmus\Nptn, Mmus\Emb" "Hsap\VSTM2L, Hsap\EMB, Hsap\BSG, Hsap\TMIGD1, Hsap\NPTN" FBgn0266306 lncRNA:CR44971 - http://flybase.org/reports/FBgn0266306 non_protein_coding_gene - - - CR44971 - CR44971 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263762 CG43679 - http://flybase.org/reports/FBgn0263762 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43679 - CG43679 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0029504 CHES-1-like Checkpoint suppressor 1-like http://flybase.org/reports/FBgn0029504 protein_coding_gene "RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN001371846 transcription regulatory region sequence-specific DNA binding ; GO:0000976 | inferred from direct assay" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001766, InterPro:IPR018122, InterPro:IPR030456 mitotic G1 DNA damage checkpoint ; GO:0031571 | inferred from genetic interaction with Mnn1 cellular response to hypoxia ; GO:0071456 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype embryonic heart tube development ; GO:0035050 | inferred from mutant phenotype regulation of cell division ; GO:0051302 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001371846 "anon-EST:Posey7, CG12690, Dmches-1, ches1, CHES-1-like, Ches-1-like, FoxN, Ches1" "IPR001766:Fork head domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR018122:Fork head domain conserved site1, IPR015943:WD40/YVTN repeat-like-containing domain, IPR030456:Fork head domain conserved site 2" CG12690 27-Aug-18 DroID_v2018_08 "Drer\foxn2a, Drer\ches1, Drer\foxm1, Drer\si:ch211-145o7.3, Drer\foxn2b, Drer\foxj3, Drer\foxj2, Drer\foxn3" "Scer\FKH2, Scer\FKH1, Scer\FHL1, Scer\HCM1" "Cele\pes-1, Cele\fkh-8" "Xtro\foxn3, Xtro\foxn2" "Mmus\Foxp1, Mmus\Foxj3, Mmus\Foxp2, Mmus\Foxm1, Mmus\Foxn2, Mmus\Foxp4, Mmus\Foxj2, Mmus\Foxn3" "Hsap\FOXP4, Hsap\FOXM1, Hsap\FOXJ2, Hsap\FOXN3, Hsap\FOXN2, Hsap\FOXP1, Hsap\FOXJ3, Hsap\FOXP2" "increased cell death,visible,lethal - all die before end of pupal stage,some die during pupal stage" "heart primordium,eye,embryonic/larval cardial cell,embryonic/larval pericardial cell" DRSC18447 E -0.214597937 -0.6701924 -0.225185765 1.860905836 -0.53349305 -0.051556223 FBgn0052504 CG32504 - http://flybase.org/reports/FBgn0052504 protein_coding_gene - - - CG32504 - - 27-Aug-18 DroID_v2018_08 - - - - - - DRSC22745 K 0.438939617 0.400901782 0.122521301 0.110423734 -1.225817522 -1.712639293 FBgn0060436 l(3)S125012b lethal (3) S125012b http://flybase.org/reports/FBgn0060436 gene - - - "1250/12, l(3)S125012b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0005267 l(3)SG87 lethal (3) SG87 http://flybase.org/reports/FBgn0005267 - gene - - - l(3)SG87 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0026263 bip1 bip1 http://flybase.org/reports/FBgn0026263 FBgn0062148 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR006612 POZ domain binding ; GO:0031208 | inferred from physical interaction with bab1 larval lymph gland hemopoiesis ; GO:0035167 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "bip-I, CG7574, anon-WO0118547.246, bip1, Bip1" "IPR006612:Zinc finger, C2CH-type" CG7574 27-Aug-18 DroID_v2018_08 - - - - - - "viable,female fertile" FBgn0085356 CG34327 - http://flybase.org/reports/FBgn0085356 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34327 - CG34327 27-Aug-18 DroID_v2018_08 - - - - - Hsap\KRTAP5-1 FBgn0266040 lncRNA:CR44805 - http://flybase.org/reports/FBgn0266040 non_protein_coding_gene - - - "CR44805, lincRNA.S3687" - CR44805 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035443 CG12010 - http://flybase.org/reports/FBgn0035443 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959, InterPro:IPR003960" - - CG12010 "IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR003960:ATPase, AAA-type, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG12010 27-Aug-18 DroID_v2018_08 "Drer\vcp, Drer\zgc:136908, Drer\spata5l1" "Scer\AFG2, Scer\CDC48" - "Xtro\spata5, Xtro\vcp" "Mmus\Vcp, Mmus\Spata5" "Hsap\SPATA5, Hsap\VCP, Hsap\ATAD2B, Hsap\SPATA5L1" "visible,body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0027903 CG12018 - http://flybase.org/reports/FBgn0027903 - protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR007185 DNA-directed DNA polymerase activity ; GO:0003887 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000045935 mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype DNA strand elongation involved in DNA replication ; GO:0006271 | inferred from biological aspect of ancestor with PANTHER:PTN000045935 delta DNA polymerase complex ; GO:0043625 | inferred from biological aspect of ancestor with PANTHER:PTN000045936 microtubule associated complex ; GO:0005875 | inferred from direct assay "BcDNA:HL03874, CG12018, 12018" "IPR007185:DNA polymerase alpha/epsilon, subunit B, IPR024826:DNA polymerase delta/II small subunit family" CG12018 27-Aug-18 DroID_v2018_08 Drer\pold2 Scer\POL31 Cele\F12F6.7 Xtro\pold2 Mmus\Pold2 Hsap\POLD2 "viable,visible" mesothoracic tergum FBgn0052220 Csas CMP-sialic acid synthase http://flybase.org/reports/FBgn0052220 protein_coding_gene N-acylneuraminate cytidylyltransferase activity ; GO:0008781 | inferred from direct assay response to heat ; GO:0009408 | inferred from mutant phenotype chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype Golgi apparatus ; GO:0005794 | inferred from direct assay trans-Golgi network ; GO:0005802 | inferred from direct assay "Csas, DmCSAS, CG32220, CSAS" "IPR003329:Acylneuraminate cytidylyltransferase, IPR029044:Nucleotide-diphospho-sugar transferases" CG32220 27-Aug-18 DroID_v2018_08 "Drer\cmasb, Drer\cmasa" - - - Mmus\Cmas Hsap\CMAS "viable,paralytic,neurophysiology defective,locomotor behavior defective,recessive" FBgn0265363 asRNA:CR44304 - http://flybase.org/reports/FBgn0265363 non_protein_coding_gene - - - CR44304 - CR44304 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0025155 ms(2)A12 ms(2)A12 http://flybase.org/reports/FBgn0025155 - gene - - - ms(2)A12 - - 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,recessive" FBgn0267041 asRNA:CR45485 - http://flybase.org/reports/FBgn0267041 non_protein_coding_gene - - - CR45485 - CR45485 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0058439 CG40439 - http://flybase.org/reports/FBgn0058439 protein_coding_gene - - - CG40439 - CG40439 27-Aug-18 DroID_v2018_08 Drer\commd8 - - Xtro\commd8 Mmus\Commd8 Hsap\COMMD8 FBgn0261289 CheB98a Chemosensory protein A 98a http://flybase.org/reports/FBgn0261289 protein_coding_gene lipid binding ; GO:0008289 | inferred from sequence alignment with HGNC:14537 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with CheB42a detection of pheromone ; GO:0043695 | inferred from expression pattern extracellular region ; GO:0005576 | inferred from sequence model extracellular space ; GO:0005615 | inferred from sequence or structural similarity with CheB42a "CG14531, CheB98a, CheB98ap" "IPR006601:Uncharacterised protein family DM11, Drosophila melanogaster" CG14531 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033520 Prx2540-1 Peroxiredoxin 2540-1 http://flybase.org/reports/FBgn0033520 protein_coding_gene peroxiredoxin activity ; GO:0051920 | inferred from electronic annotation with InterPro:IPR019479 peroxidase activity ; GO:0004601 | inferred from direct assay "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000866, InterPro:IPR019479 cell redox homeostasis ; GO:0045454 | inferred from electronic annotation with InterPro:IPR013766 hydrogen peroxide catabolic process ; GO:0042744 | inferred from direct assay" cytosol ; GO:0005829 | inferred from direct assay "CG12405, DPx-2540-1, Prx2540, DPx2540, BEST:LD11278, Prx2540-1, 1-cys peroxiredoxin DPx- 2540-1" "IPR000866:Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant, IPR012336:Thioredoxin-like fold, IPR019479:Peroxiredoxin, C-terminal, IPR024706:Peroxiredoxin, AhpC-type, IPR013766:Thioredoxin domain" CG12405 27-Aug-18 DroID_v2018_08 "Drer\prdx4, Drer\prdx1, Drer\prdx2, Drer\prdx3, Drer\prdx6" "Scer\TSA1, Scer\TSA2, Scer\PRX1" "Cele\prdx-6, Cele\prdx-3, Cele\prdx-2" Xtro\prdx6 "Mmus\Prdx2, Mmus\Prdx1, Mmus\Prdx4, Mmus\Prdx3, Mmus\Prdx6b, Mmus\Prdx6" "Hsap\PRDX3, Hsap\PRDX4, Hsap\PRDX6, Hsap\PRDX1, Hsap\PRDX2" FBgn0051315 CG31315 - http://flybase.org/reports/FBgn0051315 protein_coding_gene - - - CG31315 - - 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0027313 l(1)G0094 lethal (1) G0094 http://flybase.org/reports/FBgn0027313 - gene - - - l(1)G0094 - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority live,female sterile,partially lethal - majority die,recessive" chaeta FBgn0043589 EK2-7 EK2-7 http://flybase.org/reports/FBgn0043589 gene - - - EK2-7 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0052811 CG32811 - http://flybase.org/reports/FBgn0052811 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32811 - CG32811 27-Aug-18 DroID_v2018_08 - - - - - - DRSC22649 K -0.813369712 0.375485171 0.026245544 -0.230067764 -0.501005956 1.50853484 FBgn0036471 CG13460 - http://flybase.org/reports/FBgn0036471 protein_coding_gene - - - CG13460 - CG13460 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0005306 ms(1)244 male sterile (1) 244 http://flybase.org/reports/FBgn0005306 - gene - - - ms(1)244 - - 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,meiotic cell cycle defective,behavior defective" "meiotic cell cycle | male,meiotic anaphase I & nuclear chromosome,meiotic cell cycle & spindle | male,spermatocyte & nucleus,spermatocyte & centriole,spermatid" FBgn0266987 lncRNA:CR45438 - http://flybase.org/reports/FBgn0266987 non_protein_coding_gene - - - CR45438 - CR45438 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262547 CG43101 - http://flybase.org/reports/FBgn0262547 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43101 - CG43101 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035187 Trh Tryptophan hydroxylase http://flybase.org/reports/FBgn0035187 protein_coding_gene "amino acid binding ; GO:0016597 | inferred from electronic annotation with InterPro:IPR002912 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001273, InterPro:IPR018301 phenylalanine 4-monooxygenase activity ; GO:0004505 | inferred from direct assay tryptophan 5-monooxygenase activity ; GO:0004510 | inferred from direct assay" "aromatic amino acid family metabolic process ; GO:0009072 | inferred from electronic annotation with InterPro:IPR001273, InterPro:IPR018301 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001273, InterPro:IPR005963, InterPro:IPR018301, InterPro:IPR019773, InterPro:IPR019774 regulation of circadian sleep/wake cycle, sleep ; GO:0045187 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from mutant phenotype serotonin biosynthetic process ; GO:0042427 | inferred from direct assay" - "Trh, DTRH, CG9122, CT9937, TRH, TRHn, dTrh, DTRHn" "IPR018301:Aromatic amino acid hydroxylase, iron/copper binding site, IPR001273:Aromatic amino acid hydroxylase, IPR005963:Tryptophan 5-monooxygenase, IPR019773:Tyrosine 3-monooxygenase-like, IPR019774:Aromatic amino acid hydroxylase, C-terminal, IPR002912:ACT domain" CG9122 27-Aug-18 DroID_v2018_08 "Drer\tph2, Drer\pah, Drer\th2, Drer\th, Drer\tph1a, Drer\tph1b" - "Cele\cat-2, Cele\tph-1, Cele\pah-1" "Xtro\tph1, Xtro\pah, Xtro\th" "Mmus\Th, Mmus\Tph2, Mmus\Tph1, Mmus\Pah" "Hsap\TPH1, Hsap\TPH2, Hsap\TH, Hsap\PAH" "behavior defective,male,viable,fertile,feeding behavior defective,smell perception defective,neuroanatomy defective,partially lethal - majority die,some die during larval stage" FBgn0065327 l(2)SH1895 lethal (2) SH1895 http://flybase.org/reports/FBgn0065327 gene - - - "l(2)SH1895, l(2)SH2 1895" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0065834 l(2)SH0342 lethal (2) SH0342 http://flybase.org/reports/FBgn0065834 gene - - - "l(2)SH0342, l(2)SH2 0342" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0028850 CG15260 - http://flybase.org/reports/FBgn0028850 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype - "BG:DS07851.8, CG15260" - CG15260 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile,lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" ganglion mother cell FBgn0267711 asRNA:CR46044 - http://flybase.org/reports/FBgn0267711 non_protein_coding_gene - - - CR46044 - CR46044 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267056 lncRNA:CR45500 - http://flybase.org/reports/FBgn0267056 non_protein_coding_gene - - - CR45500 - CR45500 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034186 CG8950 - http://flybase.org/reports/FBgn0034186 protein_coding_gene "transcription factor activity, core RNA polymerase III binding ; GO:0000995 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000555283" transcription from RNA polymerase III promoter ; GO:0006383 | inferred from biological aspect of ancestor with PANTHER:PTN000555283 transcription factor TFIIIC complex ; GO:0000127 | inferred from biological aspect of ancestor with PANTHER:PTN000555283 CG8950 "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat" CG8950 27-Aug-18 DroID_v2018_08 "Drer\lig4, Drer\gtf3c3" "Scer\TFC4, Scer\DNL4" Cele\tftc-3 "Xtro\gtf3c3, Xtro\lig4" "Mmus\Lig4, Mmus\Gtf3c3" "Hsap\LIG4, Hsap\GTF3C3" viable FBgn0022351 anon-25Dc anon-25Dc http://flybase.org/reports/FBgn0022351 - gene - - - "e4, anon-25Dc" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0003000 On Open http://flybase.org/reports/FBgn0003000 - gene - - - On - - 27-Aug-18 DroID_v2018_08 - - - - - - viable wing FBgn0267953 lncRNA:CR46233 - http://flybase.org/reports/FBgn0267953 non_protein_coding_gene - - - "CR46233, lincRNA.861" - CR46233 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0024502 Aco Accordion http://flybase.org/reports/FBgn0024502 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available Aco - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0084704 836 836 http://flybase.org/reports/FBgn0084704 gene - - - 836 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034692 CG13502 - http://flybase.org/reports/FBgn0034692 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13502 "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat" CG13502 27-Aug-18 DroID_v2018_08 "Drer\ifit16, Drer\kdm6al, Drer\tomm34, Drer\ttc25, Drer\kdm6a, Drer\fkbpl, Drer\dyx1c1, Drer\tmtc3, Drer\ifit14, Drer\ogt.1, Drer\ifit15, Drer\ifit9, Drer\kdm6ba, Drer\ifit8, Drer\spag1a, Drer\bbs4, Drer\ogt.2, Drer\spag1b, Drer\ttc6" "Scer\SWA2, Scer\TAH1, Scer\CYC8" - "Xtro\bbs4, Xtro\kdm6a, Xtro\tmtc3, Xtro\ttc25, Xtro\kdm6b, Xtro\ifit5, Xtro\ttc16, Xtro\dyx1c1, Xtro\spag1, Xtro\ogt" "Mmus\Lonrf3, Mmus\Dyx1c1, Mmus\Ifit1bl1, Mmus\Uty, Mmus\Ifit3, Mmus\Ogt, Mmus\Ttc25, Mmus\Bbs4, Mmus\Ifit1bl2, Mmus\Tomm34, Mmus\Ifit3b, Mmus\Ifit2, Mmus\Ttc16, Mmus\Tmtc3, Mmus\Tmtc1, Mmus\Ttc24, Mmus\Kdm6a, Mmus\Spag1, Mmus\Ifit1, Mmus\Fkbpl, Mmus\Kdm6b" "Hsap\UTY, Hsap\IFIT3, Hsap\TTC24, Hsap\TTC32, Hsap\TTC6, Hsap\TMTC3, Hsap\TTC25, Hsap\TTC16, Hsap\DYX1C1, Hsap\IFIT1, Hsap\KDM6B, Hsap\IFIT2, Hsap\FKBPL, Hsap\BBS4, Hsap\IFIT5, Hsap\TOMM34, Hsap\SPAG1, Hsap\LONRF3, Hsap\OGT, Hsap\IFIT1B, Hsap\LONRF2, Hsap\TMTC1, Hsap\KDM6A" viable FBgn0000493 drb dark red brown http://flybase.org/reports/FBgn0000493 - gene - - - drb - - 27-Aug-18 DroID_v2018_08 - - - - - - "eye color defective,cold sensitive" "pigment cell,cold sensitive" FBgn0069138 mcl(3)Z5839 mcl(3)Z5839 http://flybase.org/reports/FBgn0069138 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z5839 - - 27-Aug-18 DroID_v2018_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0264741 CG43999 - http://flybase.org/reports/FBgn0264741 protein_coding_gene molecular_function ; GO:0003674 | no biological data available regulation of lipid metabolic process ; GO:0019216 | inferred from biological aspect of ancestor with PANTHER:PTN000281649 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000281649 "CR43999, CG43999, BcDNA:AT03227, CG13602" IPR010754:Optic atrophy 3-like CG43999 27-Aug-18 DroID_v2018_08 Drer\opa3 - Cele\H43I07.1 Xtro\opa3 Mmus\Opa3 Hsap\OPA3 FBgn0036777 CG7341 - http://flybase.org/reports/FBgn0036777 protein_coding_gene - - - CG7341 - CG7341 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0003368 sfc stiff chaetae http://flybase.org/reports/FBgn0003368 - gene - - - sfc - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive,viable,fertile" macrochaeta FBgn0032452 CG15484 - http://flybase.org/reports/FBgn0032452 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15484 - CG15484 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0052203 Spn75F Serpin 75F http://flybase.org/reports/FBgn0052203 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | NOT inferred from key residues multicellular organism reproduction ; GO:0032504 | inferred from expression pattern lateral inhibition ; GO:0046331 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence model "BG642378(6h1), CG32203, BG642378, Spn75F, 6h1" "IPR000215:Serpin family, IPR023796:Serpin domain" CG32203 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-186e20.7, Drer\serpinf2a, Drer\serpina1, Drer\serpina7, Drer\serpina1l, Drer\zgc:174260, Drer\zgc:174259, Drer\serpine1" - "Cele\srp-7, Cele\srp-2, Cele\srp-1, Cele\srp-6, Cele\srp-3" Xtro\serpinf2 "Mmus\Serpina11, Mmus\Serpina3j, Mmus\Serpina12, Mmus\Serpina1e, Mmus\Serpina16, Mmus\Serpina5, Mmus\Serpina1b, Mmus\Serpina1a, Mmus\Serpina1f, Mmus\Serpina3c, Mmus\Serpina1d, Mmus\Serpina3i, Mmus\Serpinf2, Mmus\Serpina7, Mmus\Serpina3m, Mmus\Serpina6, Mmus\Serpina1c, Mmus\Serpina3k, Mmus\Serpina3a, Mmus\Serpina9, Mmus\Serpina3f, Mmus\Serpina3n, Mmus\Serpina3b, Mmus\Serpina3g" "Hsap\SERPINA5, Hsap\SERPINA3, Hsap\SERPINA4, Hsap\SERPINA6, Hsap\SERPINA1, Hsap\SERPINA9, Hsap\SERPINA2, Hsap\SERPINA12, Hsap\SERPINF2, Hsap\SERPINA11, Hsap\SERPINA7" "viable,fertile,visible" "chaeta,trichogen cell" FBgn0019685 mbr mushroom bodies reduced http://flybase.org/reports/FBgn0019685 - gene molecular_function ; GO:0003674 | no biological data available mushroom body development ; GO:0016319 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mbr - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,male sterile,locomotor behavior defective,female limited" "adult brain,lobula,ellipsoid body,nodulus,calyx of larval mushroom body,calyx of adult mushroom body,lobe system of adult mushroom body" FBgn0002689 mbmC mushroom body miniature C http://flybase.org/reports/FBgn0002689 - gene molecular_function ; GO:0003674 | no biological data available mushroom body development ; GO:0016319 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "opa, mbmC[N28], mbmC" - - 27-Aug-18 DroID_v2018_08 - - - - - - "behavior defective,locomotor behavior defective,partially lethal - majority die,female limited" "ellipsoid body,nodulus,antennal lobe,calyx of larval mushroom body,lobe system of adult mushroom body,calyx of adult mushroom body" FBgn0043025 Adgf-A2 Adenosine deaminase-related growth factor A2 http://flybase.org/reports/FBgn0043025 protein_coding_gene "growth factor activity ; GO:0008083 | inferred from sequence or structural similarity with protein_id:BAA11812.1 inferred from direct assay growth factor activity ; GO:0008083 | inferred from sequence or structural similarity with Adgf-A, Adgf-D adenosine deaminase activity ; GO:0004000 | inferred from sequence or structural similarity with Adgf-A, Adgf-D" "spermatid development ; GO:0007286 | inferred from expression pattern cell proliferation ; GO:0008283 | inferred from sequence or structural similarity with Adgf-A, Adgf-D adenosine catabolic process ; GO:0006154 | inferred from sequence or structural similarity with Adgf-A, Adgf-D" "extracellular space ; GO:0005615 | inferred from electronic annotation with InterPro:IPR006331, InterPro:IPR013659 membrane ; GO:0016020 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model" "ADGF-A2, MSI, BcDNA:AT05468, CG32178, Adgf-A2, Msi" "IPR001365:Adenosine/AMP deaminase domain, IPR006331:Adenosine deaminase-related growth factor, IPR013659:Adenosine/AMP deaminase N-terminal, IPR032466:Metal-dependent hydrolase" CG32178 27-Aug-18 DroID_v2018_08 "Drer\cecr1b, Drer\ada, Drer\cecr1a, Drer\adal" Scer\AAH1 Cele\C44B7.12 "Xtro\ada, Xtro\cecr1, Xtro\ada.2, Xtro\adal" "Mmus\Ada, Mmus\Adal" "Hsap\ADAL, Hsap\ADA, Hsap\CECR1" " pupal stage , adult stage | male , spermatogenesis && adult stage " " testis

, spermatocyte

" spermatogenesis && adult stage " spermatid

, spermatozoon

, spermatocyte

" viable FBgn0259563 B2016 - http://flybase.org/reports/FBgn0259563 gene - - - B2016 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0029000 ms(3)mntr male sterile minotaurus http://flybase.org/reports/FBgn0029000 gene - - - ms(3)mntr - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0069167 mcl(3)Z1345 mcl(3)Z1345 http://flybase.org/reports/FBgn0069167 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z1345 - - 27-Aug-18 DroID_v2018_08 - - - - - - male fertile FBgn0035083 Tina-1 Troponin C-akin-1 http://flybase.org/reports/FBgn0035083 protein_coding_gene structural constituent of muscle ; GO:0008307 | non-traceable author statement heart development ; GO:0007507 | traceable author statement cellular_component ; GO:0005575 | no biological data available "CG2803, BEST:GM14784, Tina-1" "IPR009288:Gamma-glutamylcyclotransferase, AIG2-like, IPR013024:Gamma-glutamyl cyclotransferase-like" CG2803 27-Aug-18 DroID_v2018_08 "Drer\ggact.3, Drer\ggact.1, Drer\ggact.2" - Cele\F42A10.9 Xtro\ggact Mmus\Ggact Hsap\GGACT viable FBgn0013649 ms(2)ry5 ms(2)ry5 http://flybase.org/reports/FBgn0013649 - gene - - - "ms(2)5, ms(2)ry5" - - 27-Aug-18 DroID_v2018_08 - - - - - - male sterile FBgn0001970 Pgant35A Polypeptide N-acetylgalactosaminyltransferase 35A http://flybase.org/reports/FBgn0001970 "FBgn0027860, FBgn0032545" protein_coding_gene polypeptide N-acetylgalactosaminyltransferase activity ; GO:0004653 | inferred from direct assay polypeptide N-acetylgalactosaminyltransferase activity ; GO:0004653 | inferred from sequence or structural similarity open tracheal system development ; GO:0007424 | inferred from mutant phenotype oligosaccharide biosynthetic process ; GO:0009312 | inferred from direct assay Golgi stack ; GO:0005795 | non-traceable author statement "pgant35, CG7480, l(2)35Aa, dGalNAc-T1, pgant35A, BG:DS01068.8, GalNAc-T, l(2)br12, l35Aa, br12, A3, Pgant35A" "IPR000772:Ricin B, lectin domain, IPR001173:Glycosyltransferase 2-like, IPR029044:Nucleotide-diphospho-sugar transferases" CG7480 27-Aug-18 DroID_v2018_08 "Drer\galnt10, Drer\LOC101882942, Drer\galnt1, Drer\galnt11, Drer\galnt14, Drer\galnt7, Drer\galnt16, Drer\LOC103910015, Drer\galnt8b, Drer\wbscr17, Drer\si:ch211-15e22.3, Drer\galnt12, Drer\galnt6, Drer\galnt2, Drer\galnt13, Drer\galnt9, Drer\galnt18b, Drer\LOC100535692, Drer\LOC101886587, Drer\poc1bl, Drer\LOC100334784, Drer\galnt3, Drer\galnt8a.1, Drer\LOC568645" - "Cele\gly-3, Cele\gly-9, Cele\gly-8, Cele\gly-11, Cele\gly-7, Cele\gly-10" "Xtro\galnt4, Xtro\galnt6.1, Xtro\galnt14, Xtro\wbscr17, Xtro\galnt13, Xtro\galnt1, Xtro\galnt11, Xtro\galnt16, Xtro\galnt7, Xtro\galnt10, Xtro\galnt12, Xtro\galnt15, Xtro\galnt9, Xtro\galnt2" "Mmus\Galnt12, Mmus\Galnt14, Mmus\Galnt2, Mmus\Galntl5, Mmus\Galnt6, Mmus\Galnt5, Mmus\Galnt13, Mmus\Galnt16, Mmus\Galnt9, Mmus\Galnt10, Mmus\Galntl6, Mmus\Galnt3, Mmus\Galnt15, Mmus\Galnt4, Mmus\Galnt11, Mmus\Galnt7, Mmus\Galnt1, Mmus\Wbscr17, Mmus\Galnt18" "Hsap\GALNT8, Hsap\GALNT1, Hsap\WBSCR17, Hsap\GALNT9, Hsap\GALNT16, Hsap\GALNT6, Hsap\GALNT11, Hsap\GALNT12, Hsap\GALNT15, Hsap\GALNTL6, Hsap\GALNT7, Hsap\GALNT5, Hsap\GALNT14, Hsap\GALNT2, Hsap\GALNT3, Hsap\GALNT4, Hsap\GALNT13, Hsap\GALNTL5, Hsap\POC1B-GALNT4, Hsap\GALNT10, Hsap\GALNT18" " oogenesis stage , adult stage | female , embryonic stage | early , embryonic stage -- adult stage , embryonic stage&&larval stage&&adult stage , adult stage | male " " follicle cell

, ovary

, testis

, germline cell

" "lethal,partially lethal - majority die,wild-type,recessive,maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage,viable" "embryonic/larval dorsal trunk,embryonic/larval tracheal system" DRSC03557 K 1.199900284 0.133253465 0.213235553 0.229465897 1.648178344 0.595455836 FBgn0001700 l(1)ESHS21 lethal (1) ESHS21 http://flybase.org/reports/FBgn0001700 - gene - - - l(1)ESHS21 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0262777 Su(E1)-K - http://flybase.org/reports/FBgn0262777 gene - - - Su(E1)-K - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085609 CG41314 - http://flybase.org/reports/FBgn0085609 protein_coding_gene - - - CG41314 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038569 CG7218 - http://flybase.org/reports/FBgn0038569 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG7218 IPR008010:Tapt1 family CG7218 27-Aug-18 DroID_v2018_08 "Drer\tapt1a, Drer\tapt1" Scer\EMP65 Cele\F26F2.7 Xtro\tapt1 Mmus\Tapt1 Hsap\TAPT1 viable FBgn0034007 ND-51L2 NADH dehydrogenase (ubiquinone) 51 kDa subunit-like 2 http://flybase.org/reports/FBgn0034007 protein_coding_gene "4 iron, 4 sulfur cluster binding ; GO:0051539 | inferred from electronic annotation with InterPro:IPR019575 NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:P49821" "multicellular organism reproduction ; GO:0032504 | inferred from expression pattern mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with UniProtKB:P49821" mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:P49821 extracellular space ; GO:0005615 | inferred from direct assay "NUBM, ND-51L2, CG8102" "IPR011538:NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain, IPR019575:NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain" CG8102 27-Aug-18 DroID_v2018_08 Drer\ndufv1 - Cele\nuo-1 Xtro\ndufv1 Mmus\Ndufv1 Hsap\NDUFV1 "viable,visible" trichogen cell FBgn0037081 barc barricade http://flybase.org/reports/FBgn0037081 protein_coding_gene RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000401295 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity "neurogenesis ; GO:0022008 | inferred from mutant phenotype neuron differentiation ; GO:0030182 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from biological aspect of ancestor with PANTHER:PTN000401295" U2-type spliceosomal complex ; GO:0005684 | inferred from biological aspect of ancestor with PANTHER:PTN000401295 nucleus ; GO:0005634 | inferred from direct assay U2 snRNP ; GO:0005686 | inferred from biological aspect of ancestor with PANTHER:PTN000401295 "Tat-SF1, cg6049, cus2, CG6049, barc" "IPR000504:RNA recognition motif domain, IPR034393:TatSF1-like, IPR034392:TatSF1-like, RNA recognition motif 1" CG6049 27-Aug-18 DroID_v2018_08 Drer\htatsf1 Scer\CUS2 Cele\Y65B4A.1 Xtro\htatsf1 Mmus\Htatsf1 Hsap\HTATSF1 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0022177 l(2)k05404 lethal (2) k05404 http://flybase.org/reports/FBgn0022177 - gene - - - l(2)k05404 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0015524 otp orthopedia http://flybase.org/reports/FBgn0015524 "FBgn0034559, FBgn0047081" protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 DNA binding ; GO:0003677 | inferred from direct assay "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR017970 lateral inhibition ; GO:0046331 | inferred from mutant phenotype" - "Otp, w26, bk24, W26, CG2965, CG10036, BcDNA:RE58095, otp" "IPR003654:OAR domain, IPR017970:Homeobox, conserved site, IPR000047:Helix-turn-helix motif, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR015943:WD40/YVTN repeat-like-containing domain" CG10036 27-Aug-18 DroID_v2018_08 "Drer\otpb, Drer\otpa" - "Cele\npax-3, Cele\npax-1" Xtro\otp "Mmus\Pitx1, Mmus\Pitx2, Mmus\Pitx3, Mmus\Otp" "Hsap\OTP, Hsap\CRX, Hsap\OTX2, Hsap\ARGFX, Hsap\OTX1" "viable,visible,body color defective" "chaeta,supernumerary,mesothoracic tergum" DRSC04050 IK -0.48409083 -1.871483516 -0.366977855 0.666120827 1.289958843 2.069340552 FBgn0001392 l(1)2Cd lethal (1) 2Cd http://flybase.org/reports/FBgn0001392 - gene - - - l(1)2Cd - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0024975 CG2712 - http://flybase.org/reports/FBgn0024975 FBgn0020597 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 "CG2712, anon-3Be, EG:95B7.7, III" "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG2712 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-77f5.8, Drer\LOC100149413, Drer\LOC101882607" - Cele\ehn-3 - "Mmus\Zfp566, Mmus\Zfp709, Mmus\Zfp81, Mmus\Zfp180, Mmus\Zfp69, Mmus\Zfp558, Mmus\Zfp9, Mmus\Zfp949, Mmus\Peg3, Mmus\Zscan2, Mmus\Zfp952, Mmus\Zfp983, Mmus\Zfp955a, Mmus\Zfp101, Mmus\Zfp157, Mmus\Zfp329, Mmus\Plagl2, Mmus\Zfp78, Mmus\Zfp819, Mmus\Zfp248, Mmus\Zfp882, Mmus\Zfp105, Mmus\Mzf1, Mmus\Zfp37, Mmus\Zfp790, Mmus\Zfp961, Mmus\Zfp763, Mmus\Zfp169, Mmus\2810021J22Rik, Mmus\Zfp955b, Mmus\Zfp810, Mmus\Zfp266, Mmus\A430033K04Rik, Mmus\Gm4924, Mmus\Zfp90" "Hsap\ZNF891, Hsap\ZNF19, Hsap\ZNF133, Hsap\ZFP69, Hsap\ZNF599, Hsap\ZNF705D, Hsap\ZNF619, Hsap\ZNF124, Hsap\ZNF557, Hsap\ZNF425, Hsap\ZNF555, Hsap\ZNF491, Hsap\ZNF559-ZNF177, Hsap\ZNF558, Hsap\ZNF674, Hsap\ZNF266, Hsap\ZNF566, Hsap\ZNF25, Hsap\ZNF589, Hsap\ZNF705B, Hsap\ZNF337, Hsap\ZNF169, Hsap\ZNF554, Hsap\ZFP90, Hsap\ZNF596, Hsap\ZNF705G, Hsap\ZNF35, Hsap\ZNF560, Hsap\ZNF343, Hsap\ZNF620, Hsap\ZNF70, Hsap\PLAGL2, Hsap\ZNF248, Hsap\ZNF684, Hsap\ZNF404, Hsap\ZNF439, Hsap\ZNF529, Hsap\ZFP37, Hsap\ZNF394, Hsap\ZNF705E, Hsap\ZNF329, Hsap\ZSCAN22, Hsap\ZNF77, Hsap\ZNF705A, Hsap\ZNF846, Hsap\ZNF80, Hsap\ZNF556, Hsap\ZNF778, Hsap\ZNF559, Hsap\HKR1, Hsap\ZNF440, Hsap\ZNF69, Hsap\MZF1, Hsap\ZNF180, Hsap\ZNF10, Hsap\ZNF749, Hsap\ZNF550, Hsap\ZNF614, Hsap\ZSCAN2, Hsap\ZNF20, Hsap\ZNF582, Hsap\ZFP69B, Hsap\ZNF669" "viable,fertile" FBgn0003377 Sgs7 Salivary gland secretion 7 http://flybase.org/reports/FBgn0003377 FBgn0036166 protein_coding_gene - - extracellular space ; GO:0005615 | inferred from sequence model "sgs7, Sgs-7, sgs-7, 68C GIII, CG18087, Sgs7" - CG18087 27-Aug-18 DroID_v2018_08 - - - - - - larval stage | third instar embryonic/larval salivary gland

viable FBgn0086041 snoRNA:Me18S-A469 - http://flybase.org/reports/FBgn0086041 snoRNA_gene - - - "snoRNA:Me18S-A469, Me18S-Am469, Me18S-A469, CR34670" - CR34670 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001411 l(1)3Da lethal (1) 3Da http://flybase.org/reports/FBgn0001411 - gene - - - "RA55, l(1)3Da" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,cell lethal,germline clone" female reproductive system FBgn0017370 l(2)YOa lethal (2) YOa http://flybase.org/reports/FBgn0017370 - gene - - - l(2)YOa - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0044112 E(rst)C317 E(rst)C317 http://flybase.org/reports/FBgn0044112 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "C317, E(rst)C317" - - 27-Aug-18 DroID_v2018_08 - - - - - - viable eye FBgn0038946 rdhB retinol dehydrogenase B http://flybase.org/reports/FBgn0038946 protein_coding_gene retinol dehydrogenase activity ; GO:0004745 | inferred from mutant phenotype rhodopsin biosynthetic process ; GO:0016063 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG7077, rdhB" "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain" CG7077 27-Aug-18 DroID_v2018_08 "Drer\dhrs11b, Drer\dhrs11a, Drer\zgc:153724, Drer\zgc:92630" Scer\YMR226C "Cele\F28H7.2, Cele\H04M03.3" Xtro\dhrs11 Mmus\Dhrs11 Hsap\DHRS11 "neurophysiology defective,viable" "rhabdomere,eye" FBgn0033810 CG4646 - http://flybase.org/reports/FBgn0033810 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:SD14289, CG4646" "IPR008584:Protein of unknown function DUF866, eukaryotic" CG4646 27-Aug-18 DroID_v2018_08 Drer\si:ch211-284b7.3 Scer\YCR090C Cele\F46B6.12 Xtro\c1orf123 Mmus\0610037L13Rik Hsap\C1orf123 viable FBgn0033672 rho-7 rhomboid-7 http://flybase.org/reports/FBgn0033672 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR002610, InterPro:IPR022764 endopeptidase activity ; GO:0004175 | inferred from mutant phenotype protein binding ; GO:0005515 | inferred from physical interaction with Pink1 inferred from physical interaction with HtrA2" mitochondrial fusion ; GO:0008053 | inferred from mutant phenotype protein processing ; GO:0016485 | inferred from mutant phenotype "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002610, InterPro:IPR022764 mitochondrion ; GO:0005739 | inferred from direct assay" "CG8972, anon-WO0138581.3, rho-7, PARL, Rhomboid-7, R7, Rho-7" "IPR022764:Peptidase S54, rhomboid domain" CG8972 27-Aug-18 DroID_v2018_08 "Drer\parla, Drer\parl" Scer\PCP1 Cele\rom-5 Xtro\parl Mmus\Parl Hsap\PARL "visible,viable,male sterile,partially lethal - majority die,short lived,uncoordinated,neurophysiology defective" "eye,interommatidial bristle,testis,spermatozoon,mitochondrion,Nebenkern,seminal vesicle,indirect flight muscle,eye photoreceptor cell,rhabdomere" FBgn0003171 pink-wing pink wing http://flybase.org/reports/FBgn0003171 - gene - - - "pink-wing, pw" - - 27-Aug-18 DroID_v2018_08 - - - - - - "eye color defective,recessive,visible,viable,poor" "pigment cell,wing" FBgn0013756 Mtor Megator http://flybase.org/reports/FBgn0013756 "FBgn0019919, FBgn0022212" protein_coding_gene ribonucleoprotein complex binding ; GO:0043021 | inferred from sequence or structural similarity with SGD:S000001803 chromatin DNA binding ; GO:0031490 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q86BS3 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VRQ2 nucleocytoplasmic transporter activity ; GO:0005487 | inferred from biological aspect of ancestor with PANTHER:PTN001052033 protein import into nucleus ; GO:0006606 | inferred from electronic annotation with InterPro:IPR012929 male germ-line stem cell asymmetric division ; GO:0048133 | inferred from mutant phenotype regulation of mitotic spindle organization ; GO:0060236 | inferred from mutant phenotype regulation of chromosome segregation ; GO:0051983 | NOT inferred from mutant phenotype mitotic spindle assembly checkpoint ; GO:0007094 | inferred from mutant phenotype positive regulation of intracellular protein transport ; GO:0090316 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype nucleocytoplasmic transport ; GO:0006913 | inferred from biological aspect of ancestor with PANTHER:PTN001052033 spindle assembly ; GO:0051225 | inferred from direct assay chromatin organization involved in regulation of transcription ; GO:0034401 | inferred from mutant phenotype regulation of mitotic sister chromatid separation ; GO:0010965 | inferred from mutant phenotype regulation of mitotic spindle elongation ; GO:0032888 | NOT inferred from mutant phenotype regulation of metaphase plate congression ; GO:0090235 | inferred from mutant phenotype regulation of mitotic spindle assembly ; GO:1901673 | inferred from mutant phenotype regulation of mitotic cell cycle ; GO:0007346 | inferred from mutant phenotype response to endoplasmic reticulum stress ; GO:0034976 | inferred from mutant phenotype positive regulation of mitotic cell cycle spindle assembly checkpoint ; GO:0090267 | inferred from mutant phenotype response to heat ; GO:0009408 | inferred from direct assay germ-line stem-cell niche homeostasis ; GO:0060250 | inferred from mutant phenotype mitotic spindle elongation ; GO:0000022 | inferred from mutant phenotype positive regulation of mitotic nuclear division ; GO:0045840 | inferred from mutant phenotype chromatin organization ; GO:0006325 | inferred from mutant phenotype chromatin remodeling ; GO:0006338 | inferred from mutant phenotype positive regulation of cell division ; GO:0051781 | inferred from mutant phenotype nuclear inclusion body ; GO:0042405 | inferred from direct assay midbody ; GO:0030496 | inferred from direct assay nuclear periphery ; GO:0034399 | inferred from direct assay nuclear envelope ; GO:0005635 | inferred from direct assay spindle midzone ; GO:0051233 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay nuclear matrix ; GO:0016363 | inferred from direct assay metaphase plate ; GO:0070090 | inferred from direct assay nuclear pore ; GO:0005643 | inferred from direct assay spindle ; GO:0005819 | inferred from direct assay mitotic spindle ; GO:0072686 | inferred from direct assay kinetochore ; GO:0000776 | NOT inferred from direct assay nuclear euchromatin ; GO:0005719 | inferred from direct assay mitotic spindle ; GO:0072686 | colocalizes_with inferred from direct assay spindle matrix ; GO:1990047 | inferred from direct assay nuclear lamina ; GO:0005652 | inferred from direct assay nuclear membrane ; GO:0031965 | inferred from direct assay nucleolus ; GO:0005730 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay "Mtor, Bx34, Tpr, TPR, l(2)k03905, CG8274, MTOR, Megator" IPR012929:Nucleoprotein TPR/MLP1 CG8274 27-Aug-18 DroID_v2018_08 "Drer\tprb, Drer\tpra" "Scer\MLP2, Scer\MLP1" Cele\npp-21 Xtro\tpr Mmus\Tpr Hsap\TPR embryonic stage&&larval stage&&adult stage "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,visible,body color defective,partially lethal - majority die,some die during pupal stage" "male germline cell,cyst progenitor cell,germline stem cell,trichogen cell,mesothoracic tergum" FBgn0038601 CG18600 - http://flybase.org/reports/FBgn0038601 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR009668 DNA-directed RNA polymerase activity ; GO:0003899 | inferred from electronic annotation with InterPro:IPR009668 "transcription, DNA-templated ; GO:0006351 | inferred from electronic annotation with InterPro:IPR009668" nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR009668 "CG18600, CK01205, BEST:CK01205" "IPR009668:RNA polymerase I associated factor, A49-like" CG18600 27-Aug-18 DroID_v2018_08 Drer\polr1e Scer\RPA49 "Cele\Y45G5AM.7, Cele\rpoa-49" Xtro\polr1e Mmus\Polr1e Hsap\POLR1E viable embryonic/larval hemocyte | third instar larval stage FBgn0001081 fmb fused mushroom bodies http://flybase.org/reports/FBgn0001081 - gene - mushroom body development ; GO:0016319 | inferred from mutant phenotype - "fmb, fum" - - 27-Aug-18 DroID_v2018_08 - - - - - - "mushroom body beta-lobe,mushroom body gamma-lobe,ellipsoid body" FBgn0051338 CR31338 - http://flybase.org/reports/FBgn0051338 non_protein_coding_gene - - - CR31338 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0086445 l(2)37Cd lethal (2) 37Cd http://flybase.org/reports/FBgn0086445 protein_coding_gene "RNA polymerase III type 2 promoter sequence-specific DNA binding ; GO:0001003 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000325717 transcription factor activity, RNA polymerase III type 1 promoter sequence-specific binding, TFIIIB recruiting ; GO:0001005 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000325717 RNA polymerase III type 1 promoter sequence-specific DNA binding ; GO:0001002 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000325717" phagocytosis ; GO:0006909 | inferred from mutant phenotype transcription from RNA polymerase III type 2 promoter ; GO:0001009 | inferred from biological aspect of ancestor with PANTHER:PTN000325717 transcription factor TFIIIC complex ; GO:0000127 | inferred from biological aspect of ancestor with PANTHER:PTN000325717 "l(2)37Cd, CG10563, Cd" "IPR019136:Transcription factor IIIC, subunit 5" CG10563 27-Aug-18 DroID_v2018_08 Drer\gtf3c5 Scer\TFC1 Cele\tftc-5 Xtro\gtf3c5 Mmus\Gtf3c5 Hsap\GTF3C5 FBgn0010737 l(3)01107 lethal (3) 01107 http://flybase.org/reports/FBgn0010737 - gene - - - l(3)01107 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0015300 Ssl Suppressor of Stellate-like http://flybase.org/reports/FBgn0015300 "FBgn0014036, FBgn0045134" protein_coding_gene protein kinase regulator activity ; GO:0019887 | inferred from direct assay protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity protein kinase activity ; GO:0004672 | non-traceable author statement protein phosphorylation ; GO:0006468 | non-traceable author statement protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity "protein kinase CK2 complex ; GO:0005956 | inferred from electronic annotation with InterPro:IPR000704, InterPro:IPR016149, InterPro:IPR016150" "CK2betates, betaCK2tes, CKIIb1, CG13591, SSL, NEST:bs30a09, Su(Ste)l, Ssl, DmCK2betates, Dm-CK2-beta[Tes]" "IPR000704:Casein kinase II, regulatory subunit, IPR016149:Casein kinase II, regulatory subunit, alpha-helical" CG13591 27-Aug-18 DroID_v2018_08 Drer\csnk2b "Scer\CKB1, Scer\CKB2" Cele\kin-10 Xtro\csnk2b Mmus\Csnk2b Hsap\CSNK2B "lethal,viable" DRSC04657 K -0.09231576 0.412297162 -1.28937673 -0.339171567 2.5572306 2.199465422 FBgn0067749 l(1)G0206 lethal (1) G0206 http://flybase.org/reports/FBgn0067749 gene - - - l(1)G0206 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085773 CR40766 - http://flybase.org/reports/FBgn0085773 rRNA_gene - - - CR40766 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266942 lncRNA:CR45393 - http://flybase.org/reports/FBgn0266942 non_protein_coding_gene - - - CR45393 - CR45393 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0027610 Dic1 Dicarboxylate carrier 1 http://flybase.org/reports/FBgn0027610 - protein_coding_gene inorganic phosphate transmembrane transporter activity ; GO:0005315 | inferred from direct assay oxaloacetate transmembrane transporter activity ; GO:0015131 | inferred from direct assay succinate transmembrane transporter activity ; GO:0015141 | inferred from direct assay malate transmembrane transporter activity ; GO:0015140 | inferred from direct assay sulfate transmembrane transporter activity ; GO:0015116 | inferred from direct assay thiosulfate transmembrane transporter activity ; GO:0015117 | inferred from direct assay antiporter activity ; GO:0015297 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 succinate transmembrane transport ; GO:0071422 | inferred from direct assay sulfate transport ; GO:0008272 | inferred from direct assay malate transmembrane transport ; GO:0071423 | inferred from direct assay oxaloacetate transport ; GO:0015729 | inferred from direct assay phosphate ion transmembrane transport ; GO:0035435 | inferred from direct assay mitochondrial transport ; GO:0006839 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 thiosulfate transport ; GO:0015709 | inferred from direct assay mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 mitochondrion ; GO:0005739 | inferred from direct assay "BcDNA:GH02431, CG8790, Dic1, DmDic1p" "IPR018108:Mitochondrial substrate/solute carrier, IPR023395:Mitochondrial carrier domain" CG8790 27-Aug-18 DroID_v2018_08 "Drer\slc25a11, Drer\si:ch1073-100f3.2, Drer\slc25a35, Drer\slc25a34, Drer\mrpl12, Drer\slc25a14, Drer\slc25a10, Drer\ucp2" "Scer\DIC1, Scer\OAC1" "Cele\misc-1, Cele\slc-25A10, Cele\mrpl-12, Cele\ucp-4" "Xtro\slc25a27, Xtro\ucp2, Xtro\slc25a10, Xtro\slc25a30, Xtro\rangrf, Xtro\ucp1" "Mmus\Slc25a11, Mmus\Ucp3, Mmus\Slc25a10, Mmus\Slc25a27, Mmus\Mrpl12, Mmus\Slc25a35, Mmus\Slc25a34, Mmus\Ucp1, Mmus\Slc25a14, Mmus\Ucp2, Mmus\Slc25a30" "Hsap\SLC25A34, Hsap\SLC25A30, Hsap\SLC25A35, Hsap\UCP3, Hsap\SLC25A11, Hsap\SLC25A10, Hsap\UCP2, Hsap\UCP1, Hsap\MRPL12, Hsap\SLC25A27, Hsap\SLC25A14" viable FBgn0004910 Eip63F-1 Ecdysone-induced protein 63F 1 http://flybase.org/reports/FBgn0004910 FBgn0035474 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from direct assay salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern autophagic cell death ; GO:0048102 | inferred from expression pattern plasma membrane ; GO:0005886 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "Eip63F1, Ca[2+] binding protein, E63-1, E63F, Eip63Fa, CG15855, 63F-1, Eip63F-1, eip63F-1, Eip63-1, CBP12" "IPR018247:EF-Hand 1, calcium-binding site, IPR002048:EF-hand domain, IPR011992:EF-hand domain pair" CG15855 27-Aug-18 DroID_v2018_08 "Drer\pvalb2, Drer\cabp5a, Drer\cabp2a, Drer\calb1, Drer\cabp2b, Drer\cabp7b, Drer\calm3a, Drer\pvalb4, Drer\calm3b, Drer\calb2a, Drer\pvalb1, Drer\pvalb6, Drer\efcab11, Drer\efcab2, Drer\tnnc1b, Drer\tnnc1a, Drer\pvalb3, Drer\cabp1b, Drer\calml4b, Drer\cabp1a, Drer\rhbdl3, Drer\si:ch211-197n1.2, Drer\calm1a, Drer\calm1b, Drer\pvalb9, Drer\caln1, Drer\calml4a, Drer\caln2, Drer\cabp5b, Drer\pvalb8, Drer\cabp4, Drer\calm2a, Drer\calm2b, Drer\efcab6, Drer\tnnc2, Drer\calb2b, Drer\scgn" "Scer\CDC31, Scer\MLC1, Scer\MLC2, Scer\CMD1" "Cele\cal-2, Cele\cmd-1, Cele\cal-1, Cele\cal-3, Cele\cal-4" "Xtro\pvalb.1, Xtro\tnnc1, Xtro\cabp7, Xtro\tnnc2, Xtro\efcab6, Xtro\calb1, Xtro\cabp4, Xtro\ocm.2, Xtro\calm1, Xtro\calml4, Xtro\calm2, Xtro\ocm, Xtro\pvalb.2, Xtro\pvalb, Xtro\pgm1, Xtro\scgn, Xtro\LOC548651" "Mmus\Caln1, Mmus\Cabp7, Mmus\Tnnc1, Mmus\Rhbdl3, Mmus\Cabp1, Mmus\Efcab7, Mmus\Calm4, Mmus\Scgn, Mmus\Calb2, Mmus\Efcab6, Mmus\Ocm, Mmus\Efcab3, Mmus\Pvalb, Mmus\Efcab9, Mmus\Calb1, Mmus\Calml4, Mmus\Tnnc2, Mmus\Cabp5, Mmus\Spata21, Mmus\1700023F06Rik, Mmus\Efcab2, Mmus\Calml3, Mmus\Calm1, Mmus\Calm5, Mmus\Cabp2, Mmus\Calm3, Mmus\Calm2, Mmus\Efcab11, Mmus\Cabp4" "Hsap\CALML5, Hsap\EFCAB9, Hsap\SPATA21, Hsap\CABP7, Hsap\CALM2, Hsap\CABP5, Hsap\PVALB, Hsap\EFCAB3, Hsap\OCM2, Hsap\CALB2, Hsap\EFCAB13, Hsap\CALML3, Hsap\CALML4, Hsap\CALML6, Hsap\RHBDL3, Hsap\CALN1, Hsap\CABP4, Hsap\CALM1, Hsap\CALM3, Hsap\CALB1, Hsap\EFCAB7, Hsap\EFCAB11, Hsap\OCM, Hsap\EFCAB2, Hsap\TNNC1, Hsap\TNNC2, Hsap\SCGN, Hsap\CABP2, Hsap\CABP1, Hsap\EFCAB6" " larval stage , pupal stage | 0-8hr , pupal stage | 32-96hr , larval stage | late , embryonic stage && larval stage , embryonic stage | late " " embryonic/larval salivary gland

, embryonic/larval fat body

, ventral nerve cord

, epidermis

, embryonic/larval midgut

, larval brain

, imaginal disc

" "oxidative stress response defective,viable,fertile" FBgn0015233 Gpdh-Psi Glycerol 3 phosphate dehydrogenase pseudogene http://flybase.org/reports/FBgn0015233 - pseudogene_attribute - - - "3' gene, Gpdh-Psi" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0022379 Pt-11 Larval protein-11 http://flybase.org/reports/FBgn0022379 - gene - - - Pt-11 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266846 lncRNA:CR45308 - http://flybase.org/reports/FBgn0266846 non_protein_coding_gene - - - CR45308 - CR45308 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266758 Esyt2 Extended synaptotagmin-like protein 2 http://flybase.org/reports/FBgn0266758 protein_coding_gene calcium-dependent phospholipid binding ; GO:0005544 | inferred from sequence or structural similarity with HGNC:22211 synaptic vesicle exocytosis ; GO:0016079 | inferred from sequence or structural similarity intracellular transport ; GO:0046907 | inferred from sequence model integral component of membrane ; GO:0016021 | inferred from sequence model endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000080880 synaptic vesicle ; GO:0008021 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity with HGNC:22211 "Esyt2, CG6643, Tricalbin" "IPR000008:C2 domain, IPR031468:Synaptotagmin-like mitochondrial-lipid-binding domain" CG6643 27-Aug-18 DroID_v2018_08 "Drer\esyt2b, Drer\esyt1a, Drer\esyt2a, Drer\syt7b, Drer\syt7a, Drer\esyt3, Drer\pla2g4aa, Drer\pla2g4ab, Drer\esyt1b, Drer\mctp1b" "Scer\INN1, Scer\TCB3, Scer\TCB2, Scer\TCB1" "Cele\mctp-1, Cele\snt-2, Cele\esyt-2" "Xtro\esyt3, Xtro\esyt1, Xtro\pla2g4a, Xtro\mctp1, Xtro\esyt2" "Mmus\Esyt1, Mmus\Mctp1, Mmus\Esyt2, Mmus\Pla2g4a, Mmus\Esyt3" "Hsap\ESYT2, Hsap\PLA2G4A, Hsap\ESYT1, Hsap\MCTP1, Hsap\ESYT3" FBgn0030344 Nrd1 Nardilysin http://flybase.org/reports/FBgn0030344 protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR001431 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR011237, InterPro:IPR011249 protein binding involved in protein folding ; GO:0044183 | inferred from direct assay" proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001431 chaperone-mediated protein folding ; GO:0061077 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay "CG2025, Nrd1, dNrd1" "IPR001431:Peptidase M16, zinc-binding site, IPR007863:Peptidase M16, C-terminal, IPR011765:Peptidase M16, N-terminal, IPR011249:Metalloenzyme, LuxS/M16 peptidase-like, IPR032632:Peptidase M16, middle/third domain" CG2025 27-Aug-18 DroID_v2018_08 "Drer\nrd1a, Drer\nrd1b, Drer\ide" "Scer\STE23, Scer\AXL1" "Cele\Y70C5C.1, Cele\C02G6.1, Cele\C28F5.4, Cele\F44E7.4, Cele\C02G6.2" Xtro\nrdc "Mmus\Ide, Mmus\Nrd1" "Hsap\NRDC, Hsap\IDE" "lethal,recessive,viable" FBgn0261502 CG42650 - http://flybase.org/reports/FBgn0261502 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42650, DMG4-MB6.chr3R.6.014" IPR032004:Protein of unknown function DUF4790 CG42650 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051527 CG31527 - http://flybase.org/reports/FBgn0051527 protein_coding_gene - - - CG31527 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001852 l(1)tsUC13 lethal (1) tsUC13 http://flybase.org/reports/FBgn0001852 - gene - - - l(1)tsUC13 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,heat sensitive" FBgn0040350 CG3690 - http://flybase.org/reports/FBgn0040350 protein_coding_gene substrate-specific transmembrane transporter activity ; GO:0022891 | inferred from biological aspect of ancestor with PANTHER:PTN000756324 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 lateral inhibition ; GO:0046331 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000756324 "EG:BACR7A4.13, anon-WO0140519.250, CG3690" "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG3690 27-Aug-18 DroID_v2018_08 "Drer\svopa, Drer\sv2c, Drer\sv2bb, Drer\sv2ba, Drer\svopl, Drer\svopb, Drer\sv2, Drer\sv2a" Scer\HXT9 "Cele\C46C2.2, Cele\Y57G11C.23, Cele\C53B4.1, Cele\svop-1, Cele\ZK892.3" Xtro\sv2b "Mmus\Svopl, Mmus\Sv2b, Mmus\Sv2a, Mmus\Sv2c, Mmus\Svop" "Hsap\SVOP, Hsap\SV2A, Hsap\SV2C, Hsap\SVOPL, Hsap\SV2B" "viable,visible" "chaeta,mesothoracic tergum" FBgn0037037 CG10588 - http://flybase.org/reports/FBgn0037037 protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR001431 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR011237, InterPro:IPR011249" proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001431 - CG10588 "IPR001431:Peptidase M16, zinc-binding site, IPR007863:Peptidase M16, C-terminal, IPR011765:Peptidase M16, N-terminal, IPR011249:Metalloenzyme, LuxS/M16 peptidase-like, IPR032632:Peptidase M16, middle/third domain" CG10588 27-Aug-18 DroID_v2018_08 "Drer\nrd1b, Drer\nrd1a, Drer\ide" "Scer\STE23, Scer\AXL1" "Cele\C02G6.1, Cele\Y70C5C.1, Cele\F44E7.4, Cele\C28F5.4, Cele\C02G6.2" Xtro\nrdc "Mmus\Ide, Mmus\Nrd1" "Hsap\NRDC, Hsap\IDE" viable external sensory organ FBgn0265371 lncRNA:CR44312 - http://flybase.org/reports/FBgn0265371 non_protein_coding_gene - - - CR44312 - CR44312 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0026400 Noa36 Noa36 http://flybase.org/reports/FBgn0026400 - protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR010531 larval lymph gland hemopoiesis ; GO:0035167 | inferred from mutant phenotype "midbody ; GO:0030496 | inferred from sequence or structural similarity with UniProtKB:Q9Y3S2 nucleolus ; GO:0005730 | inferred from sequence or structural similarity with UniProtKB:Q9Y3S2 chromosome, centromeric region ; GO:0000775 | inferred from sequence or structural similarity with UniProtKB:Q9Y3S2" "NOA 36, NOA36, CG10009, Noa36, noa36" IPR010531:Zinc finger protein NOA36 CG10009 27-Aug-18 DroID_v2018_08 Drer\znf330 - - Xtro\znf330 Mmus\Zfp330 "Hsap\ZNF836, Hsap\ZNF330" "viable,fertile,partially lethal - majority die,lethal,visible" mesothoracic tergum FBgn0263860 P171 P171 http://flybase.org/reports/FBgn0263860 gene - memory ; GO:0007613 | inferred from mutant phenotype associative learning ; GO:0008306 | inferred from mutant phenotype - P171 - - 27-Aug-18 DroID_v2018_08 - - - - - - "learning defective,recessive,memory defective" FBgn0030204 Or9a Odorant receptor 9a http://flybase.org/reports/FBgn0030204 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | inferred from direct assay detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a integral component of membrane ; GO:0016021 | inferred from direct assay "9a, DOR95, 9E.1, CG15302, Or9a, OR9a, or9a, DmOr9a" "IPR004117:Olfactory receptor, insect" CG15302 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0019669 ms(2)50Ca ms(2)50Ca http://flybase.org/reports/FBgn0019669 - gene - - - ms(2)50Ca - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266391 lncRNA:CR45031 - http://flybase.org/reports/FBgn0266391 non_protein_coding_gene - - - CR45031 - CR45031 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040968 CG14933 - http://flybase.org/reports/FBgn0040968 protein_coding_gene - - - CG14933 IPR002350:Kazal domain CG14933 27-Aug-18 DroID_v2018_08 "Drer\tmeff1b, Drer\tmeff2a, Drer\tmeff2b, Drer\si:dkey-203a12.7" - Cele\ZK813.6 Xtro\tmeff1 "Mmus\Tmeff2, Mmus\Tmeff1" "Hsap\TMEFF2, Hsap\TMEFF1" viable FBgn0034717 CG5819 - http://flybase.org/reports/FBgn0034717 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - "tartan/capricious-like, CT18212, CG5819, 5819" "IPR000483:Cysteine-rich flanking region, C-terminal, IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like, IPR003591:Leucine-rich repeat, typical subtype" CG5819 27-Aug-18 DroID_v2018_08 "Drer\tlr19, Drer\tlr21, Drer\lrrtm1, Drer\lrrtm4l1, Drer\LOC563710, Drer\tlr2, Drer\lrrtm2, Drer\dnaaf1" - Cele\lron-15 Xtro\lrrtm1 "Mmus\Lrrtm1, Mmus\Tlr2, Mmus\Lrrtm4, Mmus\Dnaaf1, Mmus\Lrrtm2, Mmus\Lrrtm3" "Hsap\LRRTM2, Hsap\TLR2, Hsap\LRRTM4, Hsap\DNAAF1, Hsap\LRRTM3, Hsap\NLRC4, Hsap\LRRTM1" viable FBgn0035040 CG4741 - http://flybase.org/reports/FBgn0035040 protein_coding_gene - - - CG4741 - CG4741 27-Aug-18 DroID_v2018_08 - - - - - - DRSC25673 K -0.027019529 -0.015658976 -0.002210613 -0.02466791 -0.047734911 1.596890621 FBgn0264298 CG43776 - http://flybase.org/reports/FBgn0264298 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available extracellular region ; GO:0005576 | inferred from sequence model "CG43776, CG13569, CG13569-2" "IPR014044:CAP domain, IPR001283:Cysteine-rich secretory protein, allergen V5/Tpx-1-related" CG43776 27-Aug-18 DroID_v2018_08 "Drer\pi15b, Drer\crispld2, Drer\glipr1b, Drer\crispld1b, Drer\glipr2l, Drer\LOC100536500, Drer\crispld1a, Drer\r3hdml, Drer\glipr2, Drer\pi15a" "Scer\PRY2, Scer\PRY3, Scer\PRY1" "Cele\scl-23, Cele\lon-1" "Xtro\crisp1, Xtro\crispld2, Xtro\r3hdml, Xtro\glipr2, Xtro\MGC108118, Xtro\crisp2, Xtro\crisp3" "Mmus\Glipr1l2, Mmus\Glipr1l1, Mmus\Crisp4, Mmus\Pi15, Mmus\Crisp2, Mmus\Pi16, Mmus\Glipr2, Mmus\Glipr1, Mmus\Crispld2, Mmus\Clec18a, Mmus\Crisp3, Mmus\Crisp1, Mmus\R3hdml, Mmus\Crispld1" "Hsap\CRISP1, Hsap\GLIPR1L1, Hsap\GLIPR1L2, Hsap\CLEC18C, Hsap\CLEC18A, Hsap\PI16, Hsap\CLEC18B, Hsap\CRISP2, Hsap\CRISPLD1, Hsap\CRISPLD2, Hsap\GLIPR1, Hsap\R3HDML, Hsap\PI15, Hsap\GLIPR2" viable FBgn0259560 GG01554 - http://flybase.org/reports/FBgn0259560 gene - - - GG01554 - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,lethal - all die before end of pupal stage,some die during pupal stage" "wing cell,wing vein,leg,unguis,antennal segment,arista" FBgn0033777 CG17574 - http://flybase.org/reports/FBgn0033777 protein_coding_gene - - - "BcDNA:RH03863, CG17574" - CG17574 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-118j18.2, Drer\glipr2, Drer\crispld1a, Drer\crispld2, Drer\pi15a, Drer\LOC100536500, Drer\r3hdml, Drer\glipr1b, Drer\pi15b, Drer\crispld1b, Drer\glipr2l" "Scer\PRY2, Scer\PRY3, Scer\PRY1" - "Xtro\r3hdml, Xtro\glipr2, Xtro\crispld2, Xtro\crisp1, Xtro\crisp3, Xtro\MGC108118, Xtro\crisp2" "Mmus\Pi16, Mmus\Glipr1, Mmus\Clec18a, Mmus\Pi15, Mmus\Crispld2, Mmus\Glipr1l2, Mmus\Glipr2, Mmus\R3hdml, Mmus\Crispld1, Mmus\Crisp2, Mmus\Crisp4, Mmus\Glipr1l1, Mmus\Crisp1, Mmus\Crisp3" "Hsap\R3HDML, Hsap\CLEC18C, Hsap\CRISP1, Hsap\GLIPR1L1, Hsap\CLEC18A, Hsap\GLIPR1L2, Hsap\CRISPLD2, Hsap\GLIPR1, Hsap\CRISPLD1, Hsap\PI15, Hsap\CLEC18B, Hsap\PI16, Hsap\CRISP2, Hsap\GLIPR2" "viable,fertile" FBgn0005339 RD(2) Recovery Disruptor on 2 http://flybase.org/reports/FBgn0005339 - gene - - - RD(2) - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0015999 l(3)13m-320 lethal (3) 13m-320 http://flybase.org/reports/FBgn0015999 - gene - - - l(3)13m-320 - - 27-Aug-18 DroID_v2018_08 - - - - - - "mitotic cell cycle defective,lethal - all die before end of larval stage,recessive,some die during larval stage" "imaginal disc,cell cycle" FBgn0069068 27-25 27-25 http://flybase.org/reports/FBgn0069068 gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available 27-25 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,female sterile,germline clone" FBgn0037424 Osi15 Osiris 15 http://flybase.org/reports/FBgn0037424 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of plasma membrane ; GO:0005887 | inferred from sequence model "CG1157, Osi15, osi15" IPR012464:Protein of unknown function DUF1676 CG1157 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0283500 Sac1 Sac1 phosphatase http://flybase.org/reports/FBgn0283500 protein_coding_gene phosphatase activity ; GO:0016791 | inferred from sequence or structural similarity with UniProtKB:Q9ES21 phosphatidylinositol phosphate phosphatase activity ; GO:0052866 | inferred from direct assay "cytoplasmic microtubule organization ; GO:0031122 | inferred from mutant phenotype negative regulation of JNK cascade ; GO:0046329 | inferred from mutant phenotype inferred from genetic interaction with puc axon midline choice point recognition ; GO:0016199 | inferred from mutant phenotype synapse maturation ; GO:0060074 | inferred from mutant phenotype axo-dendritic transport ; GO:0008088 | inferred from mutant phenotype dorsal closure, amnioserosa morphology change ; GO:0046664 | inferred from mutant phenotype phosphatidylinositol metabolic process ; GO:0046488 | inferred from mutant phenotype trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype" endoplasmic reticulum membrane ; GO:0005789 | inferred from sequence or structural similarity with UniProtKB:Q9ES21 sensory dendrite ; GO:0071683 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay axon ; GO:0030424 | inferred from direct assay "Sac1, impatent, sac1, CG9128, dsac1, l(3)2107" IPR002013:SAC domain CG9128 27-Aug-18 DroID_v2018_08 "Drer\sacm1lb, Drer\sacm1la" Scer\SAC1 Cele\sac-1 Xtro\sacm1l Mmus\Sacm1l "Hsap\INPP5F, Hsap\SACM1L" "visible,lethal,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,partially lethal - majority die,partially lethal,increased cell death" "eye,embryonic/first instar larval cuticle,dorsal,dorsal hair,amnioserosa,NMJ bouton,ommatidium,interommatidial bristle,NMJ bouton | larval stage" FBgn0005573 l(3)85Ei lethal (3) 85Ei http://flybase.org/reports/FBgn0005573 - gene - - - l(3)85Ei - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0265661 lncRNA:CR44468 - http://flybase.org/reports/FBgn0265661 non_protein_coding_gene - - - "lincRNA.345, CR44468" - CR44468 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000336 cmt comet http://flybase.org/reports/FBgn0000336 - gene - - - cmt - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" "wing & trichome,cuticle" FBgn0010139 l(2)DTS20 lethal (2) DTS20 http://flybase.org/reports/FBgn0010139 - gene - - - "DTS-L20, l(2)DTS20" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,dominant,heat sensitive,recessive" "adult abdomen,dorsal" FBgn0000579 Eno Enolase http://flybase.org/reports/FBgn0000579 "FBgn0045789, FBgn0045874" protein_coding_gene "phosphopyruvate hydratase activity ; GO:0004634 | inferred from electronic annotation with InterPro:IPR000941 magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR000941, InterPro:IPR020809, InterPro:IPR020810, InterPro:IPR020811" "glycolytic process ; GO:0006096 | inferred from electronic annotation with InterPro:IPR000941, InterPro:IPR020809, InterPro:IPR020810, InterPro:IPR020811 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype" "phosphopyruvate hydratase complex ; GO:0000015 | inferred from electronic annotation with InterPro:IPR000941, InterPro:IPR020809, InterPro:IPR020810, InterPro:IPR020811 lipid particle ; GO:0005811 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay" "Eno, CG17654, T18, CT32526, Eno2, ENOA, BEST:LD15491, anon-WO0153538.76, eno" "IPR000941:Enolase, IPR029017:Enolase N-terminal domain-like, IPR029065:Enolase C-terminal domain-like, IPR020809:Enolase, conserved site, IPR020810:Enolase, C-terminal TIM barrel domain, IPR020811:Enolase, N-terminal, IPR034390:Enolase-like superfamily" CG17654 27-Aug-18 DroID_v2018_08 "Drer\eno1a, Drer\eno3, Drer\eno1b, Drer\eno2, Drer\eno4" "Scer\ERR1, Scer\ERR2, Scer\ENO2, Scer\ENO1, Scer\ERR3" Cele\enol-1 "Xtro\eno1, Xtro\eno4" "Mmus\Eno1, Mmus\Eno2, Mmus\Eno4, Mmus\Eno3, Mmus\Eno1b" "Hsap\ENO1, Hsap\ENO2, Hsap\ENO3, Hsap\ENO4" larval stage | third instar dorsal mesothoracic disc

"lethal,viable,fertile" FBgn0065961 l(2)SH0032 lethal (2) SH0032 http://flybase.org/reports/FBgn0065961 gene - - - "l(2)SH0032, l(2)SH2 0032" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0004976 Apart Apart http://flybase.org/reports/FBgn0004976 - gene - - - "Apt, apt, Apart" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,visible,dominant,viable,good,fertile" wing FBgn0028237 l(3)S002309 lethal (3) S002309 http://flybase.org/reports/FBgn0028237 gene - - - "0023/09, l(3)S002309" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0045469 Gr93c Gustatory receptor 93c http://flybase.org/reports/FBgn0045469 protein_coding_gene taste receptor activity ; GO:0008527 | non-traceable author statement sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of taste ; GO:0050909 | non-traceable author statement response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 integral component of membrane ; GO:0016021 | non-traceable author statement neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 "Gr93c, Gr93F3, CG13411, 93F.3, GR93F.3, CG31173, GR93c" IPR013604:7TM chemoreceptor CG31173 27-Aug-18 DroID_v2018_08 - - "Cele\gur-3, Cele\lite-1" - - - viable FBgn0260122 2L0445 - http://flybase.org/reports/FBgn0260122 gene - - - 2L0445 - - 27-Aug-18 DroID_v2018_08 - - - - - - viable "embryonic/larval dorsal trunk,somatic clone,embryonic/larval transverse connective,embryonic/larval tracheal system" FBgn0029837 Tsp5D Tetraspanin 5D http://flybase.org/reports/FBgn0029837 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence model "CG4690, Dm.Tsp5D, Tsp5D, tsp5D" "IPR018499:Tetraspanin/Peripherin, IPR000301:Tetraspanin, IPR008952:Tetraspanin, EC2 domain" CG4690 27-Aug-18 DroID_v2018_08 "Drer\cd63, Drer\tspan18b, Drer\tspan4b, Drer\tspan35, Drer\tspan9a, Drer\tspan18a, Drer\tspan34, Drer\zgc:64051, Drer\tspan4a, Drer\tspan12, Drer\tspan37, Drer\tspan9b" - "Cele\tsp-14, Cele\tsp-21, Cele\tsp-2, Cele\tsp-7, Cele\tsp-1, Cele\tsp-3" "Xtro\tspan9, Xtro\tspan1, Xtro\tspan16, Xtro\LOC100145428, Xtro\tspan18, Xtro\tspan4, Xtro\cd53" "Mmus\Cd63, Mmus\Cd53, Mmus\Tspan4, Mmus\Tspan12, Mmus\Tspan9, Mmus\Tspan1, Mmus\Tspan18" "Hsap\TSPAN4, Hsap\CD53, Hsap\CD63, Hsap\TSPAN12, Hsap\TSPAN16, Hsap\TSPAN1, Hsap\TSPAN18, Hsap\TSPAN9" viable FBgn0264511 lncRNA:CR43910 - http://flybase.org/reports/FBgn0264511 non_protein_coding_gene - - - CR43910 - CR43910 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030906 CG15063 - http://flybase.org/reports/FBgn0030906 protein_coding_gene - - - CG15063 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266995 lncRNA:CR45446 - http://flybase.org/reports/FBgn0266995 non_protein_coding_gene - - - CR45446 - CR45446 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037962 CG6971 - http://flybase.org/reports/FBgn0037962 protein_coding_gene dynein heavy chain binding ; GO:0045504 | inferred from sequence or structural similarity with MGI:MGI:1922813 inner dynein arm assembly ; GO:0036159 | inferred from sequence or structural similarity with UniProtKB:Q39604 cilium movement ; GO:0003341 | inferred from sequence or structural similarity with UniProtKB:Q39604 inner dynein arm ; GO:0036156 | inferred from sequence or structural similarity with UniProtKB:Q39604 "anon-WO0140519.67, CG6971, DNALI1" IPR019347:Axonemal dynein light chain CG6971 27-Aug-18 DroID_v2018_08 Drer\dnali1 - Cele\dyla-1 Xtro\dnali1 Mmus\Dnali1 Hsap\DNALI1 viable FBgn0005186 l(2)S32 lethal of Seto 32 http://flybase.org/reports/FBgn0005186 - gene - - - l(2)S32 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" "wing,leg,pupa" FBgn0039356 CG5039 - http://flybase.org/reports/FBgn0039356 protein_coding_gene - - - "BcDNA:LD35121, CG5039" - CG5039 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" FBgn0052382 sphinx2 sphinx2 http://flybase.org/reports/FBgn0052382 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern defense response to Gram-positive bacterium ; GO:0050830 | inferred from mutant phenotype innate immune response ; GO:0045087 | inferred from mutant phenotype defense response to fungus ; GO:0050832 | inferred from mutant phenotype positive regulation of Toll signaling pathway ; GO:0045752 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype extracellular region ; GO:0005576 | inferred by curator from GO:0050832 "sphinx2, CG32382, SPH194, CG8555, Sphinx2" "IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan" CG32382 27-Aug-18 DroID_v2018_08 "Drer\ela3l, Drer\ctrb1, Drer\masp2, Drer\LOC562139" - - Xtro\prtn3 "Mmus\Klk1b3, Mmus\Klk14, Mmus\C1s2, Mmus\C1s1, Mmus\Hgf" "Hsap\C1S, Hsap\KLK4" "immune response defective,viable" FBgn0065848 l(2)SH0310 lethal (2) SH0310 http://flybase.org/reports/FBgn0065848 gene - - - "l(2)SH0310, l(2)SH2 0310" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0031979 CCDC53 Coiled-coil domain containing 53 http://flybase.org/reports/FBgn0031979 protein_coding_gene - - WASH complex ; GO:0071203 | inferred from direct assay WASH complex ; GO:0071203 | inferred from sequence or structural similarity with UniProtKB:Q9Y3C0 "CG7429, CCDC53, Ccdc53, ccdc53" IPR019309:WASH complex subunit 3 CG7429 27-Aug-18 DroID_v2018_08 Drer\ccdc53 - Cele\ddl-1 Xtro\ccdc53 Mmus\Ccdc53 Hsap\WASHC3 "female fertile,viable" FBgn0015382 dust double stalk http://flybase.org/reports/FBgn0015382 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available dust - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267109 asRNA:CR45549 - http://flybase.org/reports/FBgn0267109 non_protein_coding_gene - - - CR45549 - CR45549 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031361 CG17652 - http://flybase.org/reports/FBgn0031361 protein_coding_gene small ribosomal subunit rRNA binding ; GO:0070181 | inferred from biological aspect of ancestor with PANTHER:PTN000275941 "phagocytosis ; GO:0006909 | inferred from mutant phenotype maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000462 | inferred from biological aspect of ancestor with PANTHER:PTN000275941" nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000275941 small-subunit processome ; GO:0032040 | inferred from biological aspect of ancestor with PANTHER:PTN000275941 CG17652 "IPR006984:rRNA-processing protein Fcf1/Utp23, IPR029060:PIN domain-like" CG17652 27-Aug-18 DroID_v2018_08 "Drer\utp23, Drer\anapc13" Scer\UTP23 Cele\C34E10.10 "Xtro\utp23, Xtro\anapc13.1" "Mmus\Utp23, Mmus\Anapc13" "Hsap\UTP23, Hsap\ANAPC13" FBgn0011044 l(1)Stark-c lethal (1) of Stark c http://flybase.org/reports/FBgn0011044 FBgn0010212 gene - - - "l(1)Stark-c, l(1)Sc" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0029661 CG16781 - http://flybase.org/reports/FBgn0029661 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR011016 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:26025 zinc ion binding ; GO:0008270 | inferred from sequence model protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with HGNC:26025 mitochondrial outer membrane ; GO:0005741 | inferred from sequence or structural similarity with HGNC:26025 endoplasmic reticulum membrane ; GO:0005789 | inferred from sequence or structural similarity with HGNC:26025 CG16781 "IPR011016:Zinc finger, RING-CH-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR033275:E3 ubiquitin-protein ligase MARCH-like" CG16781 27-Aug-18 DroID_v2018_08 "Drer\march5, Drer\march5l" - Cele\M110.3 Xtro\march5 Mmus\March5 Hsap\MARCH5 viable FBgn0039992 CG12416 - http://flybase.org/reports/FBgn0039992 protein_coding_gene - - - CG12416 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004932 a(1)HM27 abnormal abdomen HM27 http://flybase.org/reports/FBgn0004932 - gene - - - "l(1)HM27, a(1)HM27" - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive,cold sensitive" "tergite,sternite" FBgn0010615 l(2)06253 lethal (2) 06253 http://flybase.org/reports/FBgn0010615 - gene - - - l(2)06253 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0037003 CG18281 - http://flybase.org/reports/FBgn0037003 protein_coding_gene transporter activity ; GO:0005215 | inferred from biological aspect of ancestor with PANTHER:PTN001921112 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN001921112 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011701 CG18281 "IPR001958:Tetracycline resistance protein TetA/multidrug resistance protein MdtG, IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG18281 27-Aug-18 DroID_v2018_08 "Drer\LOC557306, Drer\hiat1b, Drer\si:ch211-87m7.2, Drer\si:dkey-5g14.1, Drer\zgc:174356, Drer\hiat1a, Drer\slc46a3, Drer\si:ch211-262i1.4" Scer\YJL163C "Cele\T25D3.4, Cele\Y71G12B.25" "Xtro\mfsd14a, Xtro\mfsd14b" "Mmus\Mfsd14b, Mmus\Slc46a3, Mmus\Slc46a1, Mmus\Mfsd14a" "Hsap\SLC46A1, Hsap\MFSD14B, Hsap\SLC46A3, Hsap\MFSD14A" FBgn0050202 tRNA:Ser-TGA-2-1 transfer RNA:Serine-TGA 2-1 http://flybase.org/reports/FBgn0050202 tRNA_gene UCA codon-amino acid adaptor activity ; GO:0033407 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033407 cytosol ; GO:0005829 | inferred by curator from GO:0033407 "CR30202, AE002575.trna4-SerTGA, tRNA:S:TGA:AE002575-a, tRNA[[Ser]], chr2R.trna48-SerTGA, tRNA-Ser-TGA-2-1, tRNA:Ser-TGA-2-1, tRNA:CR30202, UCA" - CR30202 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0041842 E(Sev-CycE)E19 E(Sev-CycE)E19 http://flybase.org/reports/FBgn0041842 gene - - - E(Sev-CycE)E19 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0266501 s-251 - http://flybase.org/reports/FBgn0266501 gene - - - s-251 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0063916 McClintock\gag McClintock element gag http://flybase.org/reports/FBgn0063916 transposable_element_gene - - - McClintock\gag - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0058043 CG40043 - http://flybase.org/reports/FBgn0058043 protein_coding_gene - - - CG40043 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039145 CG6000 - http://flybase.org/reports/FBgn0039145 protein_coding_gene - - - "BcDNA:RE30346, CG6000" IPR001763:Rhodanese-like domain CG6000 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-22i16.9, Drer\si:ch211-161h7.8, Drer\LOC561325, Drer\si:dkey-34l15.1, Drer\si:dkey-165n16.1" "Scer\RDL2, Scer\RDL1" - - "Mmus\Tstd1, Mmus\Tstd3" "Hsap\TSTD3, Hsap\TSTD1" viable FBgn0062593 Mod(var)1551 Mod(var)1551 http://flybase.org/reports/FBgn0062593 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1551, Mod(var)1551" - - 27-Aug-18 DroID_v2018_08 - - - - - - "suppressor of variegation,recessive,dominant,non-enhancer of variegation,non-suppressor of variegation,lethal" FBgn0001192 hi high http://flybase.org/reports/FBgn0001192 - gene - - - hi - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001643 l(1)dn23 lethal (1) discs normal 23 http://flybase.org/reports/FBgn0001643 - gene - - - "l(1)d.norm.-23, l(1)dn23" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0267102 lncRNA:CR45542 - http://flybase.org/reports/FBgn0267102 non_protein_coding_gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype - CR45542 - CR45542 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263035 CG43330 - http://flybase.org/reports/FBgn0263035 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43330, CG12377" - CG43330 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002369 l(3)91Fa lethal (3) 91Fa http://flybase.org/reports/FBgn0002369 FBgn0002375 gene - - - "C2, l(3)C2, l(3)BE44, l(3)BE43, l(3)BE42, l(3)BE41, l(3)BE40, l(3)91Fa" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0022951 36w 36w http://flybase.org/reports/FBgn0022951 - gene - - - 36w - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,partially" FBgn0262538 CG43092 - http://flybase.org/reports/FBgn0262538 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43092 - CG43092 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001348 l(1)1Ec lethal (1) 1Ec http://flybase.org/reports/FBgn0001348 - gene - - - "EA1, 28/6A, l(1)1Ec" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage,lethal,recessive" FBgn0084144 l(2)neo1 lethal (2) neo1 http://flybase.org/reports/FBgn0084144 gene - - - l(2)neo1 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0041625 Or65a Odorant receptor 65a http://flybase.org/reports/FBgn0041625 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | inferred from direct assay detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a "65a, LU27.2, DOR66, CG32401, Or65a" "IPR004117:Olfactory receptor, insect" CG32401 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC08808 K 1.169748629 0.471930075 0.064531934 -0.145232606 0.761275982 -1.715694135 FBgn0266031 lncRNA:CR44796 - http://flybase.org/reports/FBgn0266031 non_protein_coding_gene - - - CR44796 - CR44796 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0043070 MESK2 Misexpression suppressor of KSR 2 http://flybase.org/reports/FBgn0043070 protein_coding_gene molecular_function ; GO:0003674 | no biological data available positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with Ras85D inferred from genetic interaction with ksr cellular_component ; GO:0005575 | no biological data available "MESK2, CG15669, l(2)01467, CG15668, BcDNA:RH10174, BcDNA:LD27504, BcDNA:GH12032, mesk2, Mesk2" "IPR004142:NDRG, IPR029058:Alpha/Beta hydrolase fold" CG15669 27-Aug-18 DroID_v2018_08 "Drer\ndrg4, Drer\ndrg1a, Drer\ndrg2, Drer\ndrg3b, Drer\ndrg1b, Drer\ndrg3a" - "Cele\ZK1073.1, Cele\Y48G10A.3" "Xtro\ndrg1, Xtro\ndrg3, Xtro\ndrg4, Xtro\ndrg2" "Mmus\Ndrg1, Mmus\Ndrg4, Mmus\Ndrg3, Mmus\Ndrg2" "Hsap\NDRG2, Hsap\NDRG4, Hsap\NDRG1, Hsap\NDRG3" "viable,fertile,lethal,recessive,visible,lethal - all die before end of pupal stage,some die during pupal stage" "imaginal disc,wing vein" FBgn0043902 fad fat-head http://flybase.org/reports/FBgn0043902 gene - - - fad - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262127 kibra kibra http://flybase.org/reports/FBgn0262127 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with sav protein binding ; GO:0005515 | inferred from physical interaction with Mer protein binding ; GO:0005515 | inferred from physical interaction with ex inferred from physical interaction with wts inferred from physical interaction with Mer "regulation of hippo signaling ; GO:0035330 | inferred from mutant phenotype inferred from genetic interaction with ex inferred from genetic interaction with Mer inferred from genetic interaction with hpo regulation of hippo signaling ; GO:0035330 | inferred from mutant phenotype inferred from genetic interaction with ex inferred from genetic interaction with sav inferred from genetic interaction with Mer inferred from genetic interaction with hpo border follicle cell migration ; GO:0007298 | inferred from mutant phenotype negative regulation of glial cell proliferation ; GO:0060253 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from direct assay compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with crb regulation of hippo signaling ; GO:0035330 | inferred from mutant phenotype inferred from genetic interaction with yki inferred from genetic interaction with hpo" Kibra-Ex-Mer complex ; GO:0036375 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay apical part of cell ; GO:0045177 | inferred from direct assay "kib, kibra, kbr, CG33967, Kibra, CG7552, RE26350, CG12600, l(3)02404, l(3)j5C3, l(3)neo42, ORE-2, Kib, DmKibra" "IPR000008:C2 domain, IPR001202:WW domain" CG33967 27-Aug-18 DroID_v2018_08 "Drer\magixa, Drer\nedd4l, Drer\smurf1, Drer\hecw1b, Drer\LOC100334952, Drer\hecw2b, Drer\yap1, Drer\hecw2a, Drer\LOC564220, Drer\itcha, Drer\LOC556872, Drer\wwtr1, Drer\magi3a, Drer\wwp2, Drer\magi2a, Drer\bag3, Drer\nedd4a, Drer\magi1a, Drer\magi2b, Drer\wwc1, Drer\smurf2, Drer\wwc3" "Scer\RSP5, Scer\TOM1" - "Xtro\nedd4, Xtro\wwc1, Xtro\wwc2, Xtro\nedd4l, Xtro\hecw1, Xtro\wwp2, Xtro\smurf1, Xtro\wwc3, Xtro\bag3, Xtro\itch, Xtro\magi1, Xtro\magi3" "Mmus\Nedd4l, Mmus\Wwp2, Mmus\Nedd4, Mmus\Gas7, Mmus\Itch, Mmus\Smurf2, Mmus\Wwc1, Mmus\Magix, Mmus\Yap1, Mmus\Smurf1, Mmus\Magi3, Mmus\Hecw1, Mmus\Bag3, Mmus\Wwc2, Mmus\Wwp1, Mmus\Hecw2, Mmus\Magi1" "Hsap\MAGI1, Hsap\WWC1, Hsap\NEDD4L, Hsap\WWP1, Hsap\WWC2, Hsap\HECW2, Hsap\SMURF1, Hsap\SMURF2, Hsap\NEDD4, Hsap\ITCH, Hsap\WWC3, Hsap\MAGI3, Hsap\GAS7, Hsap\BAG3, Hsap\HECW1, Hsap\YAP1, Hsap\WWP2, Hsap\MAGIX" FBgn0065957 l(2)SH0053 lethal (2) SH0053 http://flybase.org/reports/FBgn0065957 gene - - - "l(2)SH0053, l(2)SH2 0053" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0263955 BG01042 - http://flybase.org/reports/FBgn0263955 gene - - - BG01042 - - 27-Aug-18 DroID_v2018_08 - - - - - - "long lived,male limited,short lived,female limited,starvation stress response defective,temperature response defective,gravitaxis defective" FBgn0022296 l(1)M52.3 lethal (1) M52.3 http://flybase.org/reports/FBgn0022296 - gene - - - "M52.3, l(1)M52.3" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0030813 CG4949 - http://flybase.org/reports/FBgn0030813 protein_coding_gene - - - CG4949 - CG4949 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0086205 S(ls)7 - http://flybase.org/reports/FBgn0086205 gene - - - S(ls)7 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085245 CG34216 - http://flybase.org/reports/FBgn0085245 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34216 IPR031958:Protein of unknown function DUF4778 CG34216 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039916 Ekar Eye-enriched kainate receptor http://flybase.org/reports/FBgn0039916 protein_coding_gene extracellular-glutamate-gated ion channel activity ; GO:0005234 | inferred from electronic annotation with InterPro:IPR019594 kainate selective glutamate receptor activity ; GO:0015277 | inferred from sequence or structural similarity kainate selective glutamate receptor activity ; GO:0015277 | inferred from sequence or structural similarity with HGNC:4579 "ion transport ; GO:0006811 | inferred from electronic annotation with InterPro:IPR001508 synaptic transmission, glutamatergic ; GO:0035249 | inferred from genetic interaction with Ih regulation of synaptic activity ; GO:0060025 | inferred from sequence or structural similarity with GluRIIA regulation of membrane potential in photoreceptor cell ; GO:0016057 | inferred from mutant phenotype inferred from genetic interaction with Ih cellular response to light intensity ; GO:0071484 | inferred from mutant phenotype optomotor response ; GO:0071632 | inferred from mutant phenotype" plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with GluRIIA "CT36399, DmelCG9935, CG9935, Ekar, ekar" "IPR001320:Ionotropic glutamate receptor, IPR001508:Ionotropic glutamate receptor, metazoa, IPR001828:Receptor, ligand binding region, IPR028082:Periplasmic binding protein-like I, IPR019594:Ionotropic glutamate receptor, L-glutamate and glycine-binding domain" CG9935 27-Aug-18 DroID_v2018_08 "Drer\grik5, Drer\LOC100537813, Drer\LOC100334689, Drer\grik2, Drer\grid1b, Drer\grik1a, Drer\grik1b, Drer\grid1a, Drer\grid2, Drer\grik4, Drer\LOC100331381" - "Cele\W02A2.5, Cele\F59E12.8, Cele\glr-3, Cele\glr-4, Cele\glr-6, Cele\glr-5, Cele\C08B6.5" "Xtro\grik1, Xtro\grik4" "Mmus\Grik1, Mmus\Grik4, Mmus\Grid1, Mmus\Grik5, Mmus\Grik3, Mmus\Grik2, Mmus\Grid2" "Hsap\GRID2, Hsap\GRIK1, Hsap\GRIK3, Hsap\GRID1, Hsap\GRIK5, Hsap\GRIK4, Hsap\GRIK2" viable DRSC24931 K -0.052055398 -0.620377827 -0.309879735 0.381367144 0.369896691 2.03668539 FBgn0263647 CG43638 - http://flybase.org/reports/FBgn0263647 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43638 - CG43638 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0026388 Or46a Odorant receptor 46a http://flybase.org/reports/FBgn0026388 "FBgn0026387, FBgn0053478" protein_coding_gene olfactory receptor activity ; GO:0004984 | non-traceable author statement odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | inferred from mutant phenotype olfactory receptor activity ; GO:0004984 | inferred from sequence or structural similarity with Or85e sensory perception of smell ; GO:0007608 | inferred from sequence or structural similarity with Or85e detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from mutant phenotype sensory perception of smell ; GO:0007608 | non-traceable author statement plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 integral component of membrane ; GO:0016021 | non-traceable author statement integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 integral component of membrane ; GO:0016021 | inferred from sequence model dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a "Or46aB, Or46aA, Or46b, dor19, 46b, 46a, DOR20, DOR19, CG17849, AN9, 46F.1, AN8, DOR46F.2, DOR46F.1, Or46F.1, Or46F.2, Or19, CG17848, CG33478, Or46a, Or46aa" "IPR004117:Olfactory receptor, insect" CG33478 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible" trichogen cell DRSC07490 K 0.423095351 0.1471332 -0.145503299 0.502398527 2.665955511 0.141930693 FBgn0065977 iab-8E.s iab-8E.s http://flybase.org/reports/FBgn0065977 gene - - - "IAB-8E s, iab-8E s, iab-8E.s, IAB8, 8E" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266927 lncRNA:CR45378 - http://flybase.org/reports/FBgn0266927 non_protein_coding_gene - - - CR45378 - CR45378 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0053353 5SrRNA:CR33353 5SrRNA:CR33353 http://flybase.org/reports/FBgn0053353 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33353, 5SrRNA:CR33353" - CR33353 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264886 lncRNA:CR44077 - http://flybase.org/reports/FBgn0264886 non_protein_coding_gene - - - CR44077 - CR44077 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260333 GSd423 - http://flybase.org/reports/FBgn0260333 gene - - - GSd423 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0013511 l(1)14Ah lethal (1) 14Ah http://flybase.org/reports/FBgn0013511 - gene - - - "X, l(1)X, l(1)13Fk, l(1)14Ah" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0031256 shv shriveled http://flybase.org/reports/FBgn0031256 protein_coding_gene unfolded protein binding ; GO:0051082 | inferred from electronic annotation with InterPro:IPR008971 protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR008971 positive regulation of integrin-mediated signaling pathway ; GO:2001046 | inferred from mutant phenotype male germ-line stem cell population maintenance ; GO:0036098 | inferred from mutant phenotype germ-line stem-cell niche homeostasis ; GO:0060250 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from direct assay "CG4164, shv" "IPR001623:DnaJ domain, IPR002939:Chaperone DnaJ, C-terminal, IPR008971:HSP40/DnaJ peptide-binding, IPR018253:DnaJ domain, conserved site" CG4164 27-Aug-18 DroID_v2018_08 "Drer\zgc:152986, Drer\dnajb11" "Scer\JJJ2, Scer\HLJ1, Scer\YDJ1, Scer\SCJ1, Scer\XDJ1" "Cele\dnj-26, Cele\dnj-20" Xtro\dnajb11 Mmus\Dnajb11 Hsap\DNAJB11 "viable,partially lethal - majority die,recessive" FBgn0029800 lin-52 lin-52 http://flybase.org/reports/FBgn0029800 protein_coding_gene - cell cycle ; GO:0007049 | inferred from electronic annotation with InterPro:IPR018737 negative regulation of execution phase of apoptosis ; GO:1900118 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype DRM complex ; GO:0070176 | inferred from electronic annotation with InterPro:IPR018737 nucleus ; GO:0005634 | inferred from direct assay Myb complex ; GO:0031523 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay euchromatin ; GO:0000791 | inferred from direct assay "dLin52, dLIN-52, dLin-52, CG15929, lin-52, dlin-52, dlin52, Lin52, Lin-52" IPR018737:Protein LIN52 CG15929 27-Aug-18 DroID_v2018_08 Drer\lin52 - Cele\lin-52 Xtro\lin52 "Mmus\Lin52, Mmus\Gm7020" Hsap\LIN52 "lethal,visible,somatic clone,germline clone,maternal effect,mitotic cell cycle defective,viable" "eye,somatic clone,rhabdomere | adult stage | somatic clone,ommatidium,embryo,germline clone,maternal effect,mitotic spindle | germline clone | maternal effect,metaphase plate | germline clone | maternal effect" DRSC18106 IE 1.579871404 0.184454313 3.440157772 -0.5260314 -0.496899688 -0.965500096 FBgn0043454 EP639 BEST:SD02913 http://flybase.org/reports/FBgn0043454 gene - - - "SD02913, EP639, BEST:SD02913" - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "trichogen cell,ectopic,tormogen cell,macrochaeta,adult thorax,chaeta,wing,germline cell,male,eye,scutellar bristle" FBgn0033297 Mal-A8 Maltase A8 http://flybase.org/reports/FBgn0033297 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR006047, InterPro:IPR015902" "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR006047, InterPro:IPR006589, InterPro:IPR013781" - "CT6532, Mal-A8, mal_A8, CG8690, Drome_A8" "IPR006047:Glycosyl hydrolase, family 13, catalytic domain, IPR017853:Glycoside hydrolase superfamily, IPR022567:Glycosyl hydrolase, C-terminal (DUF3459)" CG8690 27-Aug-18 DroID_v2018_08 "Drer\slc3a2a, Drer\zgc:158423, Drer\si:dkey-202g17.3, Drer\slc3a1, Drer\slc3a2b" "Scer\IMA2, Scer\IMA5, Scer\IMA3, Scer\MAL12, Scer\MAL32, Scer\IMA1, Scer\IMA4" "Cele\atgp-2, Cele\atgp-1" "Xtro\slc3a2, Xtro\slc3a1" "Mmus\Slc3a2, Mmus\Slc3a1" "Hsap\SLC3A1, Hsap\GBE1, Hsap\SLC3A2" viable FBgn0033320 CG8586 - http://flybase.org/reports/FBgn0033320 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314" extracellular region ; GO:0005576 | inferred from direct assay "CG8586, SPH58, c-SPH58" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan" CG8586 27-Aug-18 DroID_v2018_08 - - - - "Mmus\Egfbp2, Mmus\Klk1b27, Mmus\Klk1b11, Mmus\Klk1b5, Mmus\Klk1b16, Mmus\Klk11, Mmus\F11, Mmus\Klk1b8, Mmus\Klk1b22, Mmus\Klk1b26, Mmus\Klk1b1, Mmus\Klk1b4, Mmus\Klk1b3, Mmus\Klkb1, Mmus\Klk1b21, Mmus\Klk1b9, Mmus\Klk1, Mmus\4930519F16Rik, Mmus\Klk1b24" "Hsap\F11, Hsap\KLK1, Hsap\KLK3, Hsap\KLK2, Hsap\KLKB1, Hsap\KLK11" viable FBgn0060988 l(3)S027821b lethal (3) S027821b http://flybase.org/reports/FBgn0060988 gene - - - "0278/21, l(3)S027821b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0011826 Pp2B-14D Protein phosphatase 2B at 14D http://flybase.org/reports/FBgn0011826 "FBgn0005782, FBgn0005783, FBgn0015613" protein_coding_gene protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity protein serine/threonine phosphatase activity ; GO:0004722 | non-traceable author statement calmodulin binding ; GO:0005516 | traceable author statement calmodulin-dependent protein phosphatase activity ; GO:0033192 | inferred from mutant phenotype protein binding ; GO:0005515 | inferred from physical interaction with sra calcium-dependent protein serine/threonine phosphatase activity ; GO:0004723 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9XZL8 sleep ; GO:0030431 | inferred from direct assay regulation of embryonic development ; GO:0045995 | inferred from mutant phenotype meiotic nuclear division ; GO:0007126 | inferred from genetic interaction with sra protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity protein dephosphorylation ; GO:0006470 | non-traceable author statement female meiotic division ; GO:0007143 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from mutant phenotype calcineurin complex ; GO:0005955 | inferred from sequence or structural similarity "DmPp2B-14D, canA, PP2B 14D, CG9842, Pp12-14D, CnnA14D, PP2B, D33, PpD33, Pp2B-14DF, CanA14D, Pp2B-14D, PP2B-14D, CnA, Pp2B-14D/CaN, Pp2b-14D, CanA, CaNA" "IPR004843:Calcineurin-like phosphoesterase domain, ApaH type, IPR006186:Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase, IPR029052:Metallo-dependent phosphatase-like" CG9842 27-Aug-18 DroID_v2018_08 "Drer\ppp3ccb, Drer\ppp3cca, Drer\ppp3cb, Drer\ppp3ca" "Scer\CMP2, Scer\CNA1" Cele\tax-6 "Xtro\ppp3cc, Xtro\ppp3ca, Xtro\ppp3cb" "Mmus\Ppp3cc, Mmus\Ppp3cb, Mmus\Ppp3ca" "Hsap\PPP3CB, Hsap\PPP3CA, Hsap\PPP3CC" " embryonic stage , larval stage--adult stage , embryonic stage | stage <6 " " embryonic peripheral nervous system

, central nervous system

, organism

" "partially lethal - majority die,germline clone,visible,size defective,lethal,female sterile,meiotic cell cycle defective,sleep defective,locomotor behavior defective,viable" "eye,ommatidium,wing vein,wing,posterior compartment,wing blade,eye photoreceptor cell,photoreceptor cell R7,photoreceptor cell R3,photoreceptor cell R4,interommatidial bristle,egg & nuclear chromosomenos.UTR.THsimVP16,egg & spindlenos.UTR.THsimVP16,oocyte & nuclear chromatinnos.UTR.THsimVP16,oocyte & nucleusnos.UTR.THsimVP16" DRSC20270 EK -0.657160719 -0.936395856 2.226963277 1.767199934 -1.635530198 0.640051797 FBgn0038180 Cht5 Chitinase 5 http://flybase.org/reports/FBgn0038180 protein_coding_gene chitinase activity ; GO:0004568 | inferred from direct assay chitin binding ; GO:0008061 | inferred from direct assay "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR001223, InterPro:IPR001579, InterPro:IPR013781 wound healing ; GO:0042060 | inferred from mutant phenotype ecdysis, chitin-based cuticle ; GO:0018990 | inferred from mutant phenotype chitin-based cuticle development ; GO:0040003 | inferred from mutant phenotype chitin catabolic process ; GO:0006032 | inferred from direct assay" extracellular space ; GO:0005615 | inferred from direct assay "CG9307, Cht5, DmCHT5, DmCht5" "IPR001223:Glycoside hydrolase family 18, catalytic domain, IPR001579:Glycoside hydrolase, chitinase active site, IPR002557:Chitin binding domain, IPR011583:Chitinase II, IPR017853:Glycoside hydrolase superfamily, IPR029070:Chitinase insertion domain" CG9307 27-Aug-18 DroID_v2018_08 "Drer\ovgp1, Drer\si:ch211-226m16.2, Drer\chia.5, Drer\chia.2, Drer\chia.1, Drer\srl" Scer\CTS2 "Cele\cht-4, Cele\cht-1, Cele\cht-3, Cele\cht-2" "Xtro\chit1, Xtro\chia, Xtro\ctbs, Xtro\srl, Xtro\LOC548945" "Mmus\Ovgp1, Mmus\Chil6, Mmus\Chia1, Mmus\Chit1, Mmus\Chil3, Mmus\Chil4, Mmus\Ctbs, Mmus\Chil1, Mmus\Srl, Mmus\Chil5" "Hsap\CHIT1, Hsap\CHIA, Hsap\SRL, Hsap\CHI3L1, Hsap\CHI3L2, Hsap\OVGP1" "viable,fertile" FBgn0043047 anon-60Af anon-60Af http://flybase.org/reports/FBgn0043047 gene - - - anon-60Af - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038845 CG10827 - http://flybase.org/reports/FBgn0038845 protein_coding_gene alkaline phosphatase activity ; GO:0004035 | inferred from sequence or structural similarity with HGNC:439 dephosphorylation ; GO:0016311 | inferred from sequence or structural similarity with HGNC:439 cell surface ; GO:0009986 | inferred from sequence or structural similarity with HGNC:439 CG10827 "IPR001952:Alkaline phosphatase, IPR018299:Alkaline phosphatase, active site, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha, IPR017850:Alkaline-phosphatase-like, core domain" CG10827 27-Aug-18 DroID_v2018_08 "Drer\alpl, Drer\alp3, Drer\alpi.1, Drer\alpi.2" Scer\PHO8 - "Xtro\alpi.1, Xtro\alpl" "Mmus\Alppl2, Mmus\Alpi, Mmus\Akp3, Mmus\Alpl" "Hsap\ALPL, Hsap\ALPI, Hsap\ALPP, Hsap\ALPPL2" viable DRSC14269 K 0.578620853 -0.366896562 0.056720263 -0.118483537 1.949854475 0.036920914 FBgn0015357 anon-9Ba anon-9Ba http://flybase.org/reports/FBgn0015357 - gene - - - anon-9Ba - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0069937 CG41107 - http://flybase.org/reports/FBgn0069937 protein_coding_gene - - - CG41107 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035158 CG13895 - http://flybase.org/reports/FBgn0035158 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR007889, InterPro:IPR009057" - - CG13895 "IPR007889:DNA binding HTH domain, Psq-type, IPR006600:HTH CenpB-type DNA-binding domain, IPR009057:Homeobox domain-like" CG13895 27-Aug-18 DroID_v2018_08 - - Cele\unc-98 - - - viable FBgn0024833 AP-1mu "Adaptor Protein complex 1, mu subunit" http://flybase.org/reports/FBgn0024833 - protein_coding_gene clathrin binding ; GO:0030276 | inferred from sequence or structural similarity with SGD:S000006180 protein transporter activity ; GO:0008565 | inferred from mutant phenotype "intracellular protein transport ; GO:0006886 | inferred from electronic annotation with InterPro:IPR001392, InterPro:IPR018240 neurotransmitter secretion ; GO:0007269 | non-traceable author statement compound eye development ; GO:0048749 | inferred from mutant phenotype vesicle coating ; GO:0006901 | traceable author statement vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with SGD:S000006180 secretory granule organization ; GO:0033363 | inferred from mutant phenotype synaptic vesicle coating ; GO:0016183 | traceable author statement negative regulation of endocytic recycling ; GO:2001136 | inferred from mutant phenotype negative regulation of Notch signaling pathway ; GO:0045746 | inferred from genetic interaction with Dl inferred from genetic interaction with Ser inferred from genetic interaction with spdo intracellular transport ; GO:0046907 | inferred from mutant phenotype" synaptic vesicle ; GO:0008021 | traceable author statement clathrin-coated vesicle ; GO:0030136 | inferred from direct assay AP-1 adaptor complex ; GO:0030121 | inferred from mutant phenotype inferred from physical interaction with AP-1γ transcription factor AP-1 complex ; GO:0035976 | inferred from mutant phenotype inferred from physical interaction with AP-1γ AP-1 adaptor complex ; GO:0030121 | inferred from sequence or structural similarity with SGD:S000006180 coated vesicle ; GO:0030135 | traceable author statement "cg9388, CG9388, mu1, AP47, Dmu1, AP-1mu, AP-47, AP-1mu1, apm1, AP1mu1, APmu1, ap-47" "IPR001392:Clathrin adaptor, mu subunit, IPR011012:Longin-like domain, IPR018240:Clathrin adaptor, mu subunit, conserved site, IPR028565:Mu homology domain, IPR022775:AP complex, mu/sigma subunit" CG9388 27-Aug-18 DroID_v2018_08 "Drer\ldlrb, Drer\ap1m2, Drer\ap4m1, Drer\ap1m1, Drer\ap2m1a, Drer\ap1m3, Drer\ap2m1b, Drer\ap5m1" "Scer\APM4, Scer\APM2, Scer\APM3, Scer\APM1" "Cele\unc-41, Cele\dpy-23, Cele\apm-1, Cele\unc-101" "Xtro\ap1m1, Xtro\ap1m2, Xtro\ap2m1, Xtro\ap5m1, Xtro\ap4m1" "Mmus\Ap5m1, Mmus\Ap1m1, Mmus\Ap2m1, Mmus\Ap1m2, Mmus\Ap4m1" "Hsap\AP1M2, Hsap\AP4M1, Hsap\AP2M1, Hsap\AP1M1, Hsap\AP5M1" embryonic stage -- adult stage "lethal - all die before end of embryonic stage,some die during embryonic stage,viable,lethal - all die before end of first instar larval stage,some die during first instar larval stage,partially lethal - majority die,lethal - all die before end of pupal stage,some die during pupal stage,body color defective" "eye,somatic clone,tormogen cell,supernumerary,embryonic/larval salivary gland,secretory granule,embryonic/larval salivary gland | third instar larval stage,secretory granuleAB1,ommatidium,mesothoracic tergum" FBgn0031375 erm earmuff http://flybase.org/reports/FBgn0031375 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 "regulation of neurogenesis ; GO:0050767 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from mutant phenotype negative regulation of neuroblast proliferation ; GO:0007406 | inferred from mutant phenotype stem cell population maintenance ; GO:0019827 | inferred from mutant phenotype" - "CG7312, erm, CG31670, dfezl, dFezf" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG31670 27-Aug-18 DroID_v2018_08 "Drer\znf296, Drer\prdm12b, Drer\LOC100537687, Drer\fezf1, Drer\si:dkey-33c14.6, Drer\gfi1aa, Drer\gfi1b, Drer\egr2b, Drer\fezf2, Drer\zgc:113377, Drer\zbtb49, Drer\gfi1ab, Drer\osr1, Drer\znf668, Drer\sp3b, Drer\zgc:136308, Drer\osr2" Scer\AZF1 "Cele\ZK686.5, Cele\klu-1, Cele\eor-1, Cele\Y111B2A.10, Cele\ztf-6, Cele\fezf-1, Cele\zfp-2" "Xtro\sp5l, Xtro\fezf2, Xtro\fezf1, Xtro\znf630, Xtro\osr1, Xtro\znf33b, Xtro\hic1, Xtro\osr2" "Mmus\Zscan4d, Mmus\Zfp9, Mmus\Zfp992, Mmus\Gfi1, Mmus\Osr2, Mmus\2810021J22Rik, Mmus\Zscan4b, Mmus\Osr1, Mmus\9130019O22Rik, Mmus\Zfp991, Mmus\Zfp446, Mmus\Zic5, Mmus\Prdm12, Mmus\Fezf1, Mmus\Zscan4c, Mmus\Zfp444, Mmus\Fezf2, Mmus\Gfi1b, Mmus\Zscan4f, Mmus\Zscan5b" "Hsap\FEZF2, Hsap\OSR1, Hsap\FEZF1, Hsap\ZNF764, Hsap\PRDM1, Hsap\GFI1, Hsap\OSR2, Hsap\ZNF683, Hsap\PRDM12, Hsap\ZNF444, Hsap\ZNF500, Hsap\ZNF467, Hsap\GFI1B" "neuroanatomy defective,somatic clone,lethal,viable,fertile" "type II neuroblast | third instar larval stage,type II neuroblast,somatic clone,supernumerary,supernumerary | third instar larval stage,embryonic/larval neuroblast,ectopic" FBgn0003180 pyp polyphene http://flybase.org/reports/FBgn0003180 - gene - - - pyp - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,partially lethal - majority live" "eye,wing,3rd posterior cell,trident,male" FBgn0086290 GS5036 - http://flybase.org/reports/FBgn0086290 gene - - - "GS5036, 5036" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060762 l(3)S063218 lethal (3) S063218 http://flybase.org/reports/FBgn0060762 gene - - - "0632/18, l(3)S063218" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0259351 C79 - http://flybase.org/reports/FBgn0259351 gene - - - C79 - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,lethal" wing hair FBgn0028098 l(3)S073615 lethal (3) S073615 http://flybase.org/reports/FBgn0028098 gene - - - "0736/15, l(3)S073615" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0067062 O4 O4 http://flybase.org/reports/FBgn0067062 gene - - - O4 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,viable" FBgn0044442 HMS-Beagle\gag HMS-Beagle element gag http://flybase.org/reports/FBgn0044442 transposable_element_gene - - - HMS-Beagle\gag - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004581 bgcn benign gonial cell neoplasm http://flybase.org/reports/FBgn0004581 "FBgn0000965, FBgn0001096, FBgn0003066, FBgn0026784, FBgn0034917, FBgn0050170" protein_coding_gene "ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000433338 translation repressor activity, nucleic acid binding ; GO:0000900 | inferred from direct assay helicase activity ; GO:0004386 | inferred from sequence or structural similarity" spermatogenesis ; GO:0007283 | traceable author statement cell competition in a multicellular organism ; GO:0035212 | inferred from mutant phenotype negative regulation of translation ; GO:0017148 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype cystoblast division ; GO:0007282 | traceable author statement germ cell development ; GO:0007281 | traceable author statement male meiosis ; GO:0007140 | traceable author statement male germline stem cell symmetric division ; GO:0098730 | inferred from mutant phenotype germ-line stem cell population maintenance ; GO:0030718 | inferred from direct assay RNA processing ; GO:0006396 | inferred from biological aspect of ancestor with PANTHER:PTN000433338 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000433338 nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000433607 "bcgn, CG10331, CG10330, cg10331, PNBP, b(2)gcn, pep, b(2)cgn, gcn, fs(2)eoQS2, fs(2)eo6, fs(2)eo-C, ben(2)gcn, CG30170, bgcn, Bgcn, BGCN" "IPR002110:Ankyrin repeat, IPR007502:Helicase-associated domain, IPR011709:Domain of unknown function DUF1605, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR020683:Ankyrin repeat-containing domain" CG30170 27-Aug-18 DroID_v2018_08 "Drer\tdrd9, Drer\dhx57, Drer\dhx29, Drer\dhx30, Drer\dhx9, Drer\dhx36, Drer\dhx37" "Scer\ECM16, Scer\YLR419W" "Cele\rha-2, Cele\F52B5.3" "Xtro\dhx36, Xtro\tdrd9, Xtro\ythdc2, Xtro\dhx29, Xtro\dhx9, Xtro\dhx30" "Mmus\Tdrd9, Mmus\Ythdc2, Mmus\Dhx30, Mmus\Dhx57, Mmus\Dhx29, Mmus\Dhx37, Mmus\Dhx9, Mmus\Dhx36" "Hsap\DHX37, Hsap\DHX30, Hsap\TDRD9, Hsap\DHX9, Hsap\DHX57, Hsap\YTHDC2, Hsap\DHX36, Hsap\DHX29" " adult stage | male , adult stage && oogenesis stage " " female germline stem cell

, cystoblast

, cystocyte

, germarium

" "male sterile,recessive,female sterile,tumorigenic,viable,hyperplasia,cytokinesis defective,meiotic cell cycle defective" "gonad,germline stem cell,germline cell,male germline stem cell,female germline stem cell,ovary,stem cell fusome,testis,germarium,cystocyte,fusome" FBgn0031012 CG8051 - http://flybase.org/reports/FBgn0031012 protein_coding_gene - transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011701 "EP(X)1550, anon-WO03002137.1, CG8051" "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG8051 27-Aug-18 DroID_v2018_08 "Drer\slc16a6a, Drer\slc16a5b, Drer\slc16a12a, Drer\slc16a9b, Drer\slc16a7, Drer\slc16a9a, Drer\slc16a5a, Drer\slc16a12b, Drer\si:ch211-234h8.7, Drer\slc16a1a" "Scer\MCH2, Scer\ATG22, Scer\MCH4, Scer\ESBP6, Scer\MCH5" "Cele\Y59A8B.21, Cele\slcf-1" "Xtro\slc16a5, Xtro\slc16a7, Xtro\slc16a3, Xtro\slc16a9, Xtro\slc16a2, Xtro\slc16a12" "Mmus\Slc16a12, Mmus\Slc16a9, Mmus\Slc16a6, Mmus\Slc16a14, Mmus\Slc16a13, Mmus\Slc16a4, Mmus\Slc16a5, Mmus\Slc16a11" "Hsap\SLC16A12, Hsap\SLC16A7, Hsap\SLC16A3, Hsap\SLC16A9, Hsap\SLC16A5, Hsap\SLC16A8, Hsap\SLC16A10, Hsap\SLC16A13, Hsap\SLC16A6, Hsap\SLC16A14, Hsap\SLC16A11, Hsap\SLC16A1" viable FBgn0267359 GS16203 - http://flybase.org/reports/FBgn0267359 gene - - - GS16203 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065830 l(2)SH0353 lethal (2) SH0353 http://flybase.org/reports/FBgn0065830 gene - - - "l(2)SH0353, l(2)SH2 0353" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0005519 l(2)36Db lethal (2) 36Db http://flybase.org/reports/FBgn0005519 - gene - - - "l(2)36Db, l(2)36D6" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036941 CG7335 - http://flybase.org/reports/FBgn0036941 protein_coding_gene fructokinase activity ; GO:0008865 | inferred from sequence or structural similarity with HGNC:6315 ketohexokinase activity ; GO:0004454 | inferred from sequence or structural similarity with HGNC:6315 carbohydrate kinase activity ; GO:0019200 | inferred from biological aspect of ancestor with PANTHER:PTN000061853 fructose metabolic process ; GO:0006000 | inferred from electronic annotation with InterPro:IPR034093 carbohydrate phosphorylation ; GO:0046835 | inferred from sequence or structural similarity with HGNC:6315 carbohydrate phosphorylation ; GO:0046835 | inferred from biological aspect of ancestor with PANTHER:PTN000061853 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000061853 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:6315 "BcDNA:AT09463, CG7335" "IPR011611:Carbohydrate kinase PfkB, IPR034093:Ketohexokinase, IPR029056:Ribokinase-like, IPR006696:Protein of unknown function DUF423" CG7335 27-Aug-18 DroID_v2018_08 Drer\khk - "Cele\grl-31, Cele\grl-20, Cele\grl-18, Cele\grl-15, Cele\grl-6, Cele\grl-26, Cele\grl-5, Cele\grl-28, Cele\grl-30, Cele\grl-3, Cele\grl-21, Cele\grl-27, Cele\grl-29" Xtro\khk Mmus\Khk Hsap\KHK viable FBgn0265509 lncRNA:CR44371 - http://flybase.org/reports/FBgn0265509 non_protein_coding_gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype - CR44371 - CR44371 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0012299 Abd-B::Dfd Abd-B::Dfd http://flybase.org/reports/FBgn0012299 - engineered_fusion_gene - - - Abd-B::Dfd - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,heat sensitive" "larval abdominal segment,anterior,filzkorper,ectopic,embryonic abdominal segment,heat sensitive,embryonic mesothoracic segment,embryonic metathoracic segment,T1 beard,spiracular sense organ (obsolete FBbt00000431),embryonic prothoracic segment,abdominal segment,Kolbchen,denticle belt,embryonic head" FBgn0058125 CG40125 - http://flybase.org/reports/FBgn0058125 protein_coding_gene - - - CG40125 - - 27-Aug-18 DroID_v2018_08 - - - - - - DRSC21010 E 0.123257854 0.616020449 1.695077499 -6.089945634 FBgn0027226 l(1)G0307 lethal (1) G0307 http://flybase.org/reports/FBgn0027226 - gene - - - l(1)G0307 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0034476 Toll-7 Toll-7 http://flybase.org/reports/FBgn0034476 protein_coding_gene "signaling pattern recognition receptor activity ; GO:0008329 | inferred by curator from GO:0009897,GO:0010508,GO:0046790 virion binding ; GO:0046790 | inferred from direct assay neurotrophin receptor activity ; GO:0005030 | inferred from mutant phenotype" "signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR000157 cell surface pattern recognition receptor signaling pathway ; GO:0002752 | inferred by curator from GO:0009897,GO:0010508,GO:0046790 positive regulation of autophagy ; GO:0010508 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype defense response to virus ; GO:0051607 | inferred from mutant phenotype regulation of defense response to virus ; GO:0050688 | inferred from mutant phenotype" external side of plasma membrane ; GO:0009897 | inferred from direct assay "Toll-7, dToll7, toll, dTLR7, Tl-7, CT24947, CG8595, TOLL 7, toll-7" "IPR000157:Toll/interleukin-1 receptor homology (TIR) domain, IPR000483:Cysteine-rich flanking region, C-terminal, IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like" CG8595 27-Aug-18 DroID_v2018_08 "Drer\zgc:101569, Drer\tlr4bb, Drer\chadla, Drer\LOC100332783, Drer\tlr3, Drer\tlr8b, Drer\tlr2, Drer\tlr18, Drer\tlr4ba, Drer\lgi1b, Drer\nrros, Drer\lgi1a, Drer\si:dkey-182i3.11, Drer\tlr9, Drer\lgi3, Drer\LOC100332583, Drer\tlr20.2, Drer\tlr5a, Drer\chad, Drer\tlr21, Drer\tlr7, Drer\lgi2a, Drer\cd180, Drer\tlr1, Drer\LOC572462, Drer\LOC100005571, Drer\tlr5b, Drer\chadlb" Scer\CYR1 "Cele\lron-1, Cele\lron-9, Cele\pan-1, Cele\lron-2, Cele\tol-1" "Xtro\LOC100488097, Xtro\LOC100485512, Xtro\LOC100495326, Xtro\LOC100485201, Xtro\tlr5, Xtro\LOC100485706, Xtro\tlr7, Xtro\tlr3, Xtro\LOC100485164, Xtro\chadl, Xtro\tlr9, Xtro\tlr6, Xtro\tlr2" "Mmus\Tlr2, Mmus\Tlr8, Mmus\Slit1, Mmus\Cd180, Mmus\Tlr5, Mmus\Lgi1, Mmus\Tlr3, Mmus\Chad, Mmus\Lgi3, Mmus\Lgi4, Mmus\Tlr13, Mmus\Chadl, Mmus\Tlr9, Mmus\Lgi2, Mmus\Tlr4, Mmus\Tlr7, Mmus\Tlr1, Mmus\Tlr6, Mmus\Tlr12" "Hsap\CD180, Hsap\TLR7, Hsap\CHAD, Hsap\TLR10, Hsap\LGI3, Hsap\LGI1, Hsap\TLR5, Hsap\TLR1, Hsap\TLR4, Hsap\TLR6, Hsap\CHADL, Hsap\LGI2, Hsap\TLR8, Hsap\LGI4, Hsap\TLR2, Hsap\TLR9, Hsap\TLR3" " embryonic stage -- adult stage , adult stage | male " "immune response defective,lethal,partially lethal - majority die,viable,neuroanatomy defective,decreased cell death" "adult abdomen,macrochaeta,ectopic,eye,wing vein,wing,leg,ventral thoracic disc,wing disc,embryonic/larval central nervous system" FBgn0021804 l(2)k16805 lethal (2) k16805 http://flybase.org/reports/FBgn0021804 - gene - - - l(2)k16805 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0030676 CG12379 - http://flybase.org/reports/FBgn0030676 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007853 chaperone binding ; GO:0051087 | inferred from biological aspect of ancestor with PANTHER:PTN000467874 protein stabilization ; GO:0050821 | inferred from biological aspect of ancestor with PANTHER:PTN000467874 protein folding ; GO:0006457 | inferred from biological aspect of ancestor with PANTHER:PTN000467874 protein import into mitochondrial matrix ; GO:0030150 | inferred from biological aspect of ancestor with PANTHER:PTN000467874 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000467874 CG12379 "IPR024158:Mitochondrial import protein TIM15, IPR007853:Zinc finger, DNL-type" CG12379 27-Aug-18 DroID_v2018_08 "Drer\card11, Drer\card14, Drer\dnlz, Drer\card9" Scer\ZIM17 Cele\F53A3.7 "Xtro\dnlz, Xtro\card9, Xtro\card14" "Mmus\Card9, Mmus\Dnlz, Mmus\Card14, Mmus\Card11, Mmus\Card10" "Hsap\CARD14, Hsap\DNLZ, Hsap\CARD9, Hsap\CARD10" FBgn0026169 snoRNA:Psi18S-1820 - http://flybase.org/reports/FBgn0026169 - snoRNA_gene - - - "Dm-639, snoR639, H1, snoH1, CR32884, psi18s-1820 snoRNA, snoRNA H1, snoRNA:Psi18S-1820, Psi 18S-1820(SnoR639), snoRNA:H1, Sno H1, chr2R:19683803..19683909" - CR32884 27-Aug-18 DroID_v2018_08 - - - - - - embryonic stage -- adult stage FBgn0000854 fs(1)M46 female sterile (1) M46 http://flybase.org/reports/FBgn0000854 - gene - - - fs(1)M46 - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "egg,maternal effect" FBgn0259991 CG42488 - http://flybase.org/reports/FBgn0259991 protein_coding_gene - outer dynein arm assembly ; GO:0036158 | inferred from biological aspect of ancestor with PANTHER:PTN000495656 cilium movement ; GO:0003341 | inferred from biological aspect of ancestor with PANTHER:PTN000495656 axoneme ; GO:0005930 | inferred from biological aspect of ancestor with PANTHER:PTN000495656 "CG42488, Dromel_CG5116_FBtr0084877_uORF" IPR026788:Transmembrane protein 141 CG42488 27-Aug-18 DroID_v2018_08 Drer\tmem141 - - Xtro\tmem141 Mmus\Tmem141 Hsap\TMEM141 FBgn0052379 CG32379 - http://flybase.org/reports/FBgn0052379 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000834 metallocarboxypeptidase activity ; GO:0004181 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000834 extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 "CG18415, CG32379" "IPR000834:Peptidase M14, carboxypeptidase A, IPR034223:Insect gut carboxypeptidase-like, carboxypeptidase domain" CG32379 27-Aug-18 DroID_v2018_08 "Drer\cpa4, Drer\cpa6, Drer\cpb2, Drer\cpb1, Drer\cpa1, Drer\cpa5, Drer\cpo, Drer\cpa2" Scer\ECM14 "Cele\cpd-2, Cele\Y59C2A.1, Cele\F02D8.4, Cele\ZC434.9, Cele\T06A4.1, Cele\Y47G6A.19, Cele\Y18H1A.9, Cele\W01A8.6, Cele\suro-1, Cele\T06A4.3" "Xtro\cpa3, Xtro\cpa1, Xtro\cpb1, Xtro\cpo, Xtro\cpb2" "Mmus\Cpa5, Mmus\Cpa3, Mmus\Cpb2, Mmus\Cpd, Mmus\Cpa6, Mmus\Cpb1, Mmus\Cpa4, Mmus\Cpa2, Mmus\Cpa1" "Hsap\CPA6, Hsap\CPA2, Hsap\CPA4, Hsap\CPA3, Hsap\CPB1, Hsap\CPB2, Hsap\CPD, Hsap\CPA5, Hsap\CPA1, Hsap\CPO" FBgn0016939 smiUNK smell impaired unknown http://flybase.org/reports/FBgn0016939 - gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - smiUNK - - 27-Aug-18 DroID_v2018_08 - - - - - - "behavior defective,recessive" FBgn0002871 mu1 mutator 1 http://flybase.org/reports/FBgn0002871 - gene - - - "mu, mt, mu1" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0052651 CG32651 - http://flybase.org/reports/FBgn0052651 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32651 IPR031732:Protein of unknown function DUF4729 CG32651 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030183 CG15309 - http://flybase.org/reports/FBgn0030183 protein_coding_gene molecular_function ; GO:0003674 | no biological data available imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "BcDNA:GH10478, CG15309" "IPR004910:Yippee/Mis18/Cereblon, IPR034751:Yippee domain" CG15309 27-Aug-18 DroID_v2018_08 "Drer\ypel5, Drer\ypel2a, Drer\ypel1, Drer\ypel2b, Drer\ypel3" Scer\MOH1 "Cele\B0546.3, Cele\B0546.4, Cele\F37A8.5" "Xtro\ypel5, Xtro\ypel1, Xtro\ypel2" "Mmus\Ypel1, Mmus\Ypel2, Mmus\Ypel3, Mmus\Ypel5, Mmus\Ypel4" "Hsap\YPEL3, Hsap\YPEL1, Hsap\YPEL5, Hsap\YPEL4, Hsap\YPEL2" viable FBgn0069931 CG41120 - http://flybase.org/reports/FBgn0069931 protein_coding_gene - - - CG41120 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031996 CG8460 - http://flybase.org/reports/FBgn0031996 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR011583 "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR001223, InterPro:IPR013781" endomembrane system ; GO:0012505 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence or structural similarity with UniProtKB:Q9BWS9 CG8460 "IPR001223:Glycoside hydrolase family 18, catalytic domain, IPR011583:Chitinase II, IPR017853:Glycoside hydrolase superfamily" CG8460 27-Aug-18 DroID_v2018_08 Drer\chid1 - "Cele\chil-10, Cele\chil-14" Xtro\chid1 Mmus\Chid1 Hsap\CHID1 FBgn0016851 l(1)N32 lethal (1) N32 http://flybase.org/reports/FBgn0016851 - gene - - - "l(1)N32, N32" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0014267 l(2)k08225 lethal (2) k08225 http://flybase.org/reports/FBgn0014267 - gene molecular_function ; GO:0003674 | no biological data available imaginal disc growth ; GO:0007446 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "l(2)82/25, l(2)k08225" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" "embryonic/larval brain,brain" FBgn0028888 CG4168 - http://flybase.org/reports/FBgn0028888 protein_coding_gene - - - "CG4168, BG:DS03192.2" "IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like" CG4168 27-Aug-18 DroID_v2018_08 "Drer\lrrc23, Drer\si:dkey-182i3.11, Drer\igfals" "Scer\ILV5, Scer\CYR1, Scer\VID22" "Cele\lron-14, Cele\lron-15, Cele\F08G2.5, Cele\lron-11" - "Mmus\Id3, Mmus\Lrrc23, Mmus\Nepn, Mmus\Igfals" "Hsap\LRRC23, Hsap\IGFALS" FBgn0067638 wey weyprecht http://flybase.org/reports/FBgn0067638 gene - bicoid mRNA localization ; GO:0045450 | inferred from mutant phenotype pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype - wey - - 27-Aug-18 DroID_v2018_08 - - - - - - female sterile "follicle cell,germline clone" FBgn0010185 tu(3)1b tu(3)1b http://flybase.org/reports/FBgn0010185 - gene - - - tu(3)1b - - 27-Aug-18 DroID_v2018_08 - - - - - - "melanotic mass phenotype,partially lethal - majority die,some die during larval stage" FBgn0020267 n-judah n-judah http://flybase.org/reports/FBgn0020267 - gene - - - n-judah - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002140 l(2)K305 lethal (2) K305 http://flybase.org/reports/FBgn0002140 - gene - - - l(2)K305 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0263619 asRNA:ASTR - http://flybase.org/reports/FBgn0263619 non_protein_coding_gene - - - CR43628 - CR43628 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0063924 Kaz1-ORFA Kaz1-ORFA http://flybase.org/reports/FBgn0063924 pseudogene_attribute - - - "ORF A, CG33045, Kaz1, CG33790, Kaz1-ORFA, Kaz1-ORF A, CR33790" IPR002350:Kazal domain CR33790 27-Aug-18 DroID_v2018_08 - - - - - - DRSC08669 K 0.326169449 0.057840784 0.010269493 0.222864967 -1.951156028 -0.47099077 FBgn0053639 CG33639 - http://flybase.org/reports/FBgn0053639 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from electronic annotation with InterPro:IPR000276 G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity neuropeptide receptor activity ; GO:0008188 | inferred from sequence model G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR000276 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR017452 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from sequence model" "CG5936, CG16958, anon-WO0170980.41, anon-WO0170980.40, CG33639" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG33639 27-Aug-18 DroID_v2018_08 Drer\gpr142 - "Cele\Y70D2A.1, Cele\AH9.1, Cele\C17H11.1, Cele\B0563.6" - "Mmus\Adra1a, Mmus\Gpr142, Mmus\Gpr139" "Hsap\GPR142, Hsap\GPR139" viable DRSC22820 EK 0.587255647 1.492565 -2.488665965 0.112975947 0.756068648 1.91784939 FBgn0000863 fs(1)M57 female sterile (1) M57 http://flybase.org/reports/FBgn0000863 - gene - - - fs(1)M57 - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive,lethal,maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage" "egg,maternal effect,chorion | maternal effect" FBgn0264468 asRNA:CR43876 - http://flybase.org/reports/FBgn0264468 non_protein_coding_gene - - - CR43876 - CR43876 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051719 RluA-1 RluA-1 http://flybase.org/reports/FBgn0051719 protein_coding_gene "pseudouridine synthase activity ; GO:0009982 | inferred from electronic annotation with InterPro:IPR006145, InterPro:IPR006224, InterPro:IPR006225, InterPro:IPR020103 RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR006145, InterPro:IPR006224, InterPro:IPR006225, InterPro:IPR020103" "pseudouridine synthesis ; GO:0001522 | inferred from electronic annotation with InterPro:IPR006145, InterPro:IPR006224, InterPro:IPR006225, InterPro:IPR020103" - "RluA1, CG31719, CG7475, CG13143, RluA-1" "IPR006145:Pseudouridine synthase, RsuA/RluB/C/D/E/F, IPR006224:Pseudouridine synthase, RluC/RluD, conserved site, IPR006225:Pseudouridine synthase, RluC/RluD, IPR020103:Pseudouridine synthase, catalytic domain" CG31719 27-Aug-18 DroID_v2018_08 "Drer\rpusd4, Drer\rpusd2, Drer\rpusd1" "Scer\PUS9, Scer\PUS6, Scer\PUS5, Scer\RIB2" Cele\K07E8.7 "Xtro\rpusd2, Xtro\rpusd3, Xtro\rpusd1" "Mmus\Rpusd3, Mmus\Rpusd2, Mmus\Rpusd4, Mmus\Rpusd1" "Hsap\RPUSD4, Hsap\RPUSD1, Hsap\RPUSD3, Hsap\RPUSD2" "viable,fertile" FBgn0070029 BG00158 BG00158 http://flybase.org/reports/FBgn0070029 gene - - - BG00158 - - 27-Aug-18 DroID_v2018_08 - - - - - - stress response defective FBgn0084500 lep leprechaun http://flybase.org/reports/FBgn0084500 gene - - - "E-3c, lep" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0260656 CG42539 - http://flybase.org/reports/FBgn0260656 protein_coding_gene - - - "CG42539, HCD15482" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060894 l(3)S044437 lethal (3) S044437 http://flybase.org/reports/FBgn0060894 gene - - - "0444/37, l(3)S044437" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0065887 l(2)SH0226 lethal (2) SH0226 http://flybase.org/reports/FBgn0065887 gene - - - "l(2)SH0226, l(2)SH2 0226" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0010034 E(var)7 Enhancer of variegation http://flybase.org/reports/FBgn0010034 - gene - - - "Evar7, E(var)7" - - 27-Aug-18 DroID_v2018_08 - - - - - - enhancer of variegation FBgn0053746 snmRNA:430t snmRNA:430:CR33746 http://flybase.org/reports/FBgn0053746 non_protein_coding_gene - - - "CR33746, snmRNA:430:CR33746" - CR33746 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0027176 l(2)60Ah lethal (2) 60Ah http://flybase.org/reports/FBgn0027176 - gene - - - "ET/141, l(2)60Ah" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0065847 l(2)SH0315 lethal (2) SH0315 http://flybase.org/reports/FBgn0065847 gene - - - "l(2)SH0315, l(2)SH2 0315" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0085455 CG34426 - http://flybase.org/reports/FBgn0085455 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "CG34426, CG13307" IPR002557:Chitin binding domain CG34426 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0043782 Burdock\gag Burdock element gag http://flybase.org/reports/FBgn0043782 transposable_element_gene - - - Burdock\gag - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085813 18SrRNA-Psi:CR41602 18S ribosomal RNA pseudogene:CR41602 http://flybase.org/reports/FBgn0085813 pseudogene_attribute - - - "CR41602, 18SrRNA-Psi:CR41602" - CR41602 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065404 l(2)SH1594 lethal (2) SH1594 http://flybase.org/reports/FBgn0065404 gene - - - "l(2)SH1594, l(2)SH2 1594" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0041112 l(3)cl-R3 lethal (3) cell lethal R3 http://flybase.org/reports/FBgn0041112 gene - - - "cl3R3, l(3)cl-R3" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,cell lethalcell lethal,somatic clone" FBgn0065873 l(2)SH0251 lethal (2) SH0251 http://flybase.org/reports/FBgn0065873 gene - - - "l(2)SH0251, l(2)SH2 0251" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0259391 C432 - http://flybase.org/reports/FBgn0259391 gene - - - C432 - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,lethal" wing hair FBgn0262827 CG43198 - http://flybase.org/reports/FBgn0262827 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43198, DMG6-MB6.chrX.13.005" - CG43198 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038865 cDIP Common Dpr-interacting protein http://flybase.org/reports/FBgn0038865 protein_coding_gene - - - "CT11359, CG10824, DIPc, 10824, cDIP" "IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like" CG10824 27-Aug-18 DroID_v2018_08 "Drer\tlr4al, Drer\tlr4bb, Drer\lrrc15, Drer\zgc:153913, Drer\lrrc17, Drer\lrrc6, Drer\tlr4ba" - - Xtro\lrrc15 "Mmus\Cpn2, Mmus\Lrrc17, Mmus\Lrrc15, Mmus\Lrrc6, Mmus\Gp5" "Hsap\GP5, Hsap\LRRC6, Hsap\LRRC15, Hsap\LRRC17, Hsap\CPN2" "partially lethal - majority die,some die during pupal stage" FBgn0002568 luc luckenhaft http://flybase.org/reports/FBgn0002568 - gene molecular_function ; GO:0003674 | no biological data available cellularization ; GO:0007349 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available luc - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "stage 5 embryo,maternal effect,embryonic/first instar larval cuticle,embryonic head,embryonic segment" FBgn0029506 Tsp42Ee Tetraspanin 42Ee http://flybase.org/reports/FBgn0029506 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence model fusome ; GO:0045169 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "CG10106, Dm.Tsp42Ee, BcDNA:LD16071, anon-WO0118547.151, Tsp42Ee" "IPR018499:Tetraspanin/Peripherin, IPR000301:Tetraspanin, IPR008952:Tetraspanin, EC2 domain" CG10106 27-Aug-18 DroID_v2018_08 Drer\cd63 - "Cele\tsp-1, Cele\tsp-2, Cele\tsp-7, Cele\tsp-3, Cele\tsp-14" Xtro\cd63 Mmus\Cd63 Hsap\CD63 viable FBgn0000872 fs(1)M68 female sterile (1) M68 http://flybase.org/reports/FBgn0000872 - gene - - - fs(1)M68 - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive,lethal,maternal effect" FBgn0035647 CG10486 - http://flybase.org/reports/FBgn0035647 protein_coding_gene organic anion transmembrane transporter activity ; GO:0008514 | inferred from biological aspect of ancestor with PANTHER:PTN001936837 "transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005828, InterPro:IPR005829" integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001175408 CG10486 "IPR005829:Sugar transporter, conserved site, IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG10486 27-Aug-18 DroID_v2018_08 "Drer\LOC100334012, Drer\LOC101884074, Drer\slc22a13, Drer\oatx, Drer\slc22a21, Drer\zgc:175176, Drer\zmp:0000001102, Drer\slc22a7b.1, Drer\slc22a7b.3, Drer\slc22a6l, Drer\slc22a5, Drer\sv2, Drer\slc22a7b.2" "Scer\QDR3, Scer\TPO2, Scer\TPO1, Scer\HXT2, Scer\YHK8, Scer\FLR1, Scer\GIT1, Scer\DTR1, Scer\QDR2, Scer\HXT9, Scer\AQR1, Scer\TPO3, Scer\HXT5, Scer\PHO84, Scer\QDR1" "Cele\C46C2.2, Cele\Y51A2D.18, Cele\B0361.11, Cele\Y57G11C.23, Cele\ZK892.3, Cele\T22F7.1, Cele\Y66D12A.13, Cele\B0252.3, Cele\C53B4.1, Cele\oct-1, Cele\C06H5.6" Xtro\slc22a6 "Mmus\Slc22a30, Mmus\Slc22a27, Mmus\Slc22a26, Mmus\Slc22a5, Mmus\Sv2c, Mmus\Slc22a21, Mmus\Slc22a6, Mmus\Slc22a19, Mmus\Slc22a20, Mmus\Svop, Mmus\Slc22a14, Mmus\Slc22a16, Mmus\Slc22a2, Mmus\Slc22a23, Mmus\Slc22a4, Mmus\Slc22a29, Mmus\Slc22a22, Mmus\Slc22a8, Mmus\Slc22a7, Mmus\Slc22a28" "Hsap\SLC22A24, Hsap\SLC22A12, Hsap\SLC22A11, Hsap\SLC22A5, Hsap\SLC22A4, Hsap\SLC22A9, Hsap\SLC22A8, Hsap\SVOP, Hsap\SV2C, Hsap\SLC22A6, Hsap\SLC22A25, Hsap\SV2B, Hsap\SLC22A7, Hsap\SLC22A10, Hsap\SLC22A23, Hsap\SLC22A1, Hsap\SLC22A2" "viable,fertile" FBgn0036282 Smyd4-2 "SET and MYND domain containing, class 4, member 2" http://flybase.org/reports/FBgn0036282 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with ebi histone deacetylase binding ; GO:0042826 | inferred from physical interaction with HDAC1 inferred from physical interaction with HDAC3 negative regulation of gene expression ; GO:0010629 | inferred from direct assay compound eye photoreceptor development ; GO:0042051 | inferred from mutant phenotype eclosion ; GO:0007562 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG14122, dSmyd4, Smyd4-2, Smyd4" IPR011990:Tetratricopeptide-like helical domain CG14122 27-Aug-18 DroID_v2018_08 "Drer\smyd3, Drer\smyd4, Drer\smyd1b, Drer\smyd2b, Drer\smyd2a, Drer\smyd1a" "Scer\SET6, Scer\SET5" "Cele\set-3, Cele\set-18, Cele\set-10" "Xtro\smyd1, Xtro\smyd5, Xtro\smyd4" "Mmus\Smyd2, Mmus\Smyd4, Mmus\Zmynd15, Mmus\Smyd3, Mmus\Smyd1, Mmus\Smyd5" "Hsap\SMYD5, Hsap\SMYD2, Hsap\SMYD1, Hsap\ZMYND15, Hsap\SMYD3, Hsap\SMYD4" "viable,fertile,lethal,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0051678 CG31678 - http://flybase.org/reports/FBgn0051678 protein_coding_gene - lateral inhibition ; GO:0046331 | inferred from mutant phenotype - "38D.30, CG17466, CG17465, CG31678" "IPR008979:Galactose-binding domain-like, IPR012919:SUN domain" CG31678 27-Aug-18 DroID_v2018_08 Drer\suco Scer\SLP1 Cele\suco-1 Xtro\suco Mmus\Suco Hsap\SUCO "viable,fertile,visible,body color defective,lethal - all die before end of pupal stage,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" FBgn0031146 CG15449 - http://flybase.org/reports/FBgn0031146 protein_coding_gene - - - CG15449 - CG15449 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0040990 CG15156 - http://flybase.org/reports/FBgn0040990 protein_coding_gene - - - CG15156 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031981 CG7466 - http://flybase.org/reports/FBgn0031981 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097" - membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002165 CG7466 "IPR000152:EGF-type aspartate/asparagine hydroxylation site, IPR000742:EGF-like domain, IPR000859:CUB domain, IPR001881:EGF-like calcium-binding domain, IPR002049:Laminin EGF domain, IPR002165:Plexin repeat, IPR013032:EGF-like, conserved site, IPR018097:EGF-like calcium-binding, conserved site, IPR016201:PSI domain, IPR015915:Kelch-type beta propeller, IPR015916:Galactose oxidase, beta-propeller" CG7466 27-Aug-18 DroID_v2018_08 "Drer\tmeff1a, Drer\atrnl1b, Drer\atrnl1a, Drer\megf8, Drer\tmeff2a, Drer\atrn, Drer\tmeff1b, Drer\tmem145, Drer\tmeff2b" - "Cele\unc-52, Cele\tag-53" "Xtro\megf8, Xtro\atrnl1, Xtro\atrn" "Mmus\Tmeff2, Mmus\Atrn, Mmus\Atrnl1, Mmus\Tmeff1, Mmus\Megf8, Mmus\Pafah1b3" "Hsap\ATRN, Hsap\MSANTD3-TMEFF1, Hsap\MEGF8, Hsap\TMEFF2, Hsap\ATRNL1, Hsap\TMEFF1" viable FBgn0283728 CG31600 - http://flybase.org/reports/FBgn0283728 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR008952 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "CG31600, Dm.Tsp40A, Tsp40A" "IPR018499:Tetraspanin/Peripherin, IPR008952:Tetraspanin, EC2 domain" CG31600 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034689 CG2921 - http://flybase.org/reports/FBgn0034689 protein_coding_gene enzyme binding ; GO:0019899 | inferred from sequence or structural similarity with HGNC:17872 protein methylation ; GO:0006479 | inferred from sequence or structural similarity with HGNC:17872 regulation of response to DNA damage stimulus ; GO:2001020 | inferred from sequence or structural similarity with HGNC:17872 cellular_component ; GO:0005575 | no biological data available CG2921 IPR002791:Domain of unknown function DUF89 CG2921 27-Aug-18 DroID_v2018_08 Drer\armt1 Scer\YMR027W Cele\F31D4.2 Xtro\armt1 Mmus\Armt1 Hsap\ARMT1 "viable,fertile" FBgn0263853 GS9605 - http://flybase.org/reports/FBgn0263853 gene - - - GS9605 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060475 l(3)S111703 lethal (3) S111703 http://flybase.org/reports/FBgn0060475 gene - - - "1117/03, l(3)S111703" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0052060 CG32060 - http://flybase.org/reports/FBgn0052060 protein_coding_gene - - - CG32060 - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible" "chaeta,supernumerary,trichogen cell" FBgn0000851 fs(1)M40 female sterile (1) M40 http://flybase.org/reports/FBgn0000851 - gene - - - fs(1)M40 - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive,lethal,rescuable maternal effect,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "egg,maternal effect" FBgn0259756 ms(2)Fra-1 - http://flybase.org/reports/FBgn0259756 gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype chromosome organization ; GO:0051276 | inferred from mutant phenotype - ms(2)Fra-1 - - 27-Aug-18 DroID_v2018_08 - - - - - - male sterile "Y chromosome loop,spermatozoon" FBgn0027094 AlaRS Alanyl-tRNA synthetase http://flybase.org/reports/FBgn0027094 - protein_coding_gene "alanine-tRNA ligase activity ; GO:0004813 | inferred from electronic annotation with InterPro:IPR018162, InterPro:IPR018164, InterPro:IPR018165, InterPro:IPR023033 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR012947, InterPro:IPR018162, InterPro:IPR018164, InterPro:IPR018165 amino acid binding ; GO:0016597 | inferred from biological aspect of ancestor with PANTHER:PTN000206950 alanine-tRNA ligase activity ; GO:0004813 | traceable author statement tRNA binding ; GO:0000049 | inferred from biological aspect of ancestor with PANTHER:PTN000206904" "alanyl-tRNA aminoacylation ; GO:0006419 | inferred from electronic annotation with InterPro:IPR018162, InterPro:IPR018164, InterPro:IPR018165 tRNA modification ; GO:0006400 | inferred from biological aspect of ancestor with PANTHER:PTN000206950 alanyl-tRNA aminoacylation ; GO:0006419 | traceable author statement" "cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR002318, InterPro:IPR018162 cytoplasm ; GO:0005737 | traceable author statement" "Aats-ala, AlaRS, alaS, ARS, CG13391" "IPR002318:Alanine-tRNA ligase, class IIc, IPR003156:DHHA1 domain, IPR012947:Threonyl/alanyl tRNA synthetase, SAD, IPR009000:Translation protein, beta-barrel domain, IPR018163:Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain, IPR018164:Alanyl-tRNA synthetase, class IIc, N-terminal, IPR018165:Alanyl-tRNA synthetase, class IIc, core domain, IPR018162:Alanine-tRNA ligase, class IIc, anti-codon-binding domain, IPR023033:Alanine-tRNA ligase, eukaryota/bacteria" CG13391 27-Aug-18 DroID_v2018_08 "Drer\aars2, Drer\aars" Scer\ALA1 "Cele\aars-1, Cele\aars-2" Xtro\aars "Mmus\Aars2, Mmus\Aars" "Hsap\AARS, Hsap\AARS2" embryonic stage embryonic/larval salivary gland

lethal FBgn0002467 l(3)SG22 lethal (3) SG22 http://flybase.org/reports/FBgn0002467 - gene - - - "l(3)15m-15, l(3)SG22" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" imaginal disc FBgn0035328 yellow-g2 yellow-g2 http://flybase.org/reports/FBgn0035328 protein_coding_gene - melanin biosynthetic process ; GO:0042438 | inferred from biological aspect of ancestor with PANTHER:PTN000000448 cuticle pigmentation ; GO:0048067 | inferred from biological aspect of ancestor with PANTHER:PTN000000448 - "CG13804, yellow-g2, yel-g2, yg2, g2" "IPR017996:Major royal jelly protein/protein yellow, IPR011042:Six-bladed beta-propeller, TolB-like" CG13804 27-Aug-18 DroID_v2018_08 Drer\dpm3 - "Cele\F49E11.8, Cele\fbxa-76, Cele\C24H12.1, Cele\T27A1.3" Xtro\dpm3 Mmus\Dpm3 Hsap\DPM3 viable FBgn0038889 Fancm Fanconi anemia group M helicase http://flybase.org/reports/FBgn0038889 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR006935 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR006935 3'-5' DNA helicase activity ; GO:0043138 | inferred from sequence or structural similarity with SGD:S000001441 helicase activity ; GO:0004386 | inferred from sequence or structural similarity reciprocal DNA recombination ; GO:0035825 | inferred from mutant phenotype double-strand break repair via synthesis-dependent strand annealing ; GO:0045003 | inferred from mutant phenotype DNA repair ; GO:0006281 | inferred from mutant phenotype recombinational repair ; GO:0000725 | inferred from sequence or structural similarity with SGD:S000001441 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000001441 "cg7922, Fancm, CG7922" "IPR001650:Helicase, C-terminal, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR006935:Helicase/UvrB, N-terminal" CG7922 27-Aug-18 DroID_v2018_08 "Drer\dhx58, Drer\ifih1, Drer\dicer1, Drer\fancm" "Scer\MPH1, Scer\IRC3" "Cele\dcr-1, Cele\drh-1, Cele\drh-3" "Xtro\ddx58, Xtro\ifih1, Xtro\dhx58, Xtro\fancm, Xtro\dicer1" "Mmus\Dhx58, Mmus\Ddx58, Mmus\Fancm, Mmus\Ifih1, Mmus\Dicer1" "Hsap\DICER1, Hsap\IFIH1, Hsap\DHX58, Hsap\DDX58, Hsap\FANCM" FBgn0261358 CG42635 - http://flybase.org/reports/FBgn0261358 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42635, CG15149" - CG42635 27-Aug-18 DroID_v2018_08 - - Cele\ska-3 - - - viable FBgn0065816 l(2)SH0378 lethal (2) SH0378 http://flybase.org/reports/FBgn0065816 gene - - - "l(2)SH0378, l(2)SH2 0378" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0025742 mtm myotubularin http://flybase.org/reports/FBgn0025742 - protein_coding_gene protein tyrosine phosphatase activity ; GO:0004725 | inferred from electronic annotation with InterPro:IPR016130 protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | inferred from sequence or structural similarity with protein_id:AAC51682.1 inferred from sequence or structural similarity with protein_id:CAA89640.1 protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | non-traceable author statement phosphatidylinositol-3-phosphatase activity ; GO:0004438 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Sbf dephosphorylation ; GO:0016311 | inferred from electronic annotation with InterPro:IPR016130 protein dephosphorylation ; GO:0006470 | non-traceable author statement response to wounding ; GO:0009611 | inferred from mutant phenotype mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype chromosome segregation ; GO:0007059 | inferred from mutant phenotype endocytic recycling ; GO:0032456 | inferred from mutant phenotype cortical actin cytoskeleton organization ; GO:0030866 | inferred from mutant phenotype cell projection assembly ; GO:0030031 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay "MTM1, CG9115, dMTMH1, mtm" "IPR004182:GRAM domain, IPR010569:Myotubularin-like phosphatase domain, IPR016130:Protein-tyrosine phosphatase, active site, IPR030564:Myotubularin family, IPR011993:PH domain-like, IPR029021:Protein-tyrosine phosphatase-like, IPR003595:Protein-tyrosine phosphatase, catalytic" CG9115 27-Aug-18 DroID_v2018_08 "Drer\mtmr7b, Drer\zgc:154055, Drer\mtmr10, Drer\mtmr9, Drer\mtmr2, Drer\mtmr8, Drer\mtmr12, Drer\mtmr6, Drer\mtmr7a, Drer\mtmr1b, Drer\mtm1, Drer\mtmr1a" Scer\YMR1 "Cele\mtm-6, Cele\mtm-1" "Xtro\mtmr12, Xtro\LOC100216114, Xtro\asb12.2, Xtro\mtmr6, Xtro\mtmr1, Xtro\mtmr7, Xtro\mtmr9, Xtro\mtmr2, Xtro\mtmr10, Xtro\mtm1" "Mmus\Mtmr1, Mmus\Mtmr11, Mmus\Mtmr6, Mmus\Mtm1, Mmus\Mtmr9, Mmus\Mtmr7, Mmus\Mtmr12, Mmus\Mtmr10, Mmus\Mtmr2" "Hsap\MTMR6, Hsap\MTMR2, Hsap\MTMR11, Hsap\MTMR1, Hsap\MTMR7, Hsap\MTMR8, Hsap\MTMR10, Hsap\MTMR12, Hsap\MTMR9, Hsap\MTM1" "lethal - all die before end of larval stage,some die during third instar larval stage,wound healing defective,lethal - all die before end of P-stage,some die during pharate adult stage,lethal,majority die during pupal stage,developmental rate defective,flightless,viable" "embryonic/larval hemocyte,sessile hemocyte,abdominal temporary eclosion muscle DA,temporary eclosion muscle,testis sheath muscle,T-tubuleMef2.PR,macrophage" FBgn0259703 CG42357 - http://flybase.org/reports/FBgn0259703 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG32308, CG42357" - CG42357 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262996 lncRNA:CR43304 - http://flybase.org/reports/FBgn0262996 non_protein_coding_gene - - - CR43304 - CR43304 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0019773 l(1)38 lethal (1) 38 http://flybase.org/reports/FBgn0019773 - gene - - - l(1)38 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0033257 sand sandman http://flybase.org/reports/FBgn0033257 protein_coding_gene "potassium channel activity ; GO:0005267 | inferred from sequence or structural similarity with Task7, Task6" "cellular response to dopamine ; GO:1903351 | inferred from mutant phenotype potassium ion transmembrane transport ; GO:0071805 | inferred from sequence or structural similarity with Task7, Task6 negative regulation of membrane potential ; GO:0045837 | inferred from mutant phenotype negative regulation of circadian sleep/wake cycle, sleep ; GO:0042321 | inferred from mutant phenotype" "integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with Task7, Task6" "anon-WO0109301.46, anon-WO0109301.45, anon-WO0109301.44, anon-WO0109301.43, anon-WO0109301.42, anon-WO0109301.41, anon-WO0109301.40, anon-WO0109301.39, anon-WO0109301.5, CG8713, sand" "IPR003280:Two pore domain potassium channel, IPR013099:Potassium channel domain" CG8713 27-Aug-18 DroID_v2018_08 "Drer\kcnk5a, Drer\kcnk10a, Drer\kcnk7, Drer\kcnk18, Drer\kcnk5b, Drer\kcnk6, Drer\kcnk10b, Drer\kcnk1a, Drer\kcnk1b, Drer\kcnk2a" Scer\TOK1 "Cele\twk-13, Cele\twk-28, Cele\twk-48, Cele\twk-39" "Xtro\kcnk1, Xtro\kcnk2, Xtro\kcnk10, Xtro\kcnk5, Xtro\kcnk4, Xtro\LOC100486031, Xtro\kcnk7, Xtro\kcnk18, Xtro\kcnk16, Xtro\kcnk6" "Mmus\Kcnk7, Mmus\Kcnk6, Mmus\Kcnk5, Mmus\Kcnk18, Mmus\Kcnk16, Mmus\Kcnk10, Mmus\Kcnk1, Mmus\Kcnk4, Mmus\Kcnk2" "Hsap\KCNK1, Hsap\KCNK10, Hsap\KCNK6, Hsap\KCNK7, Hsap\KCNK16, Hsap\KCNK17, Hsap\KCNK5, Hsap\KCNK2, Hsap\KCNK4, Hsap\KCNK18" "viable,fertile" FBgn0003380 Sh Shaker http://flybase.org/reports/FBgn0003380 "FBgn0030885, FBgn0030888, FBgn0064981" protein_coding_gene "voltage-gated potassium channel activity ; GO:0005249 | inferred from electronic annotation with InterPro:IPR003968, InterPro:IPR003972, InterPro:IPR004048, InterPro:IPR028325 voltage-gated cation channel activity ; GO:0022843 | inferred from direct assay voltage-gated potassium channel activity ; GO:0005249 | non-traceable author statement voltage-gated potassium channel activity ; GO:0005249 | traceable author statement" "protein homooligomerization ; GO:0051260 | inferred from electronic annotation with InterPro:IPR003131 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005821 potassium ion transport ; GO:0006813 | inferred from electronic annotation with InterPro:IPR003968, InterPro:IPR003972, InterPro:IPR004048, InterPro:IPR028325 regulation of synaptic activity ; GO:0060025 | inferred from mutant phenotype larval locomotory behavior ; GO:0008345 | inferred from mutant phenotype positive regulation of membrane potential ; GO:0045838 | inferred from mutant phenotype positive regulation of circadian sleep/wake cycle, sleep ; GO:0045938 | inferred from mutant phenotype detection of visible light ; GO:0009584 | inferred from mutant phenotype behavioral response to ether ; GO:0048150 | non-traceable author statement sleep ; GO:0030431 | inferred from mutant phenotype sensory perception of taste ; GO:0050909 | non-traceable author statement learning or memory ; GO:0007611 | non-traceable author statement regulation of circadian sleep/wake cycle, sleep ; GO:0045187 | inferred from mutant phenotype flight behavior ; GO:0007629 | inferred from mutant phenotype mating behavior, sex discrimination ; GO:0048047 | inferred from direct assay action potential ; GO:0001508 | inferred from mutant phenotype courtship behavior ; GO:0007619 | traceable author statement potassium ion transport ; GO:0006813 | traceable author statement cellular response to dopamine ; GO:1903351 | inferred from mutant phenotype proboscis extension reflex ; GO:0007637 | inferred from mutant phenotype axon extension ; GO:0048675 | inferred from mutant phenotype courtship behavior ; GO:0007619 | non-traceable author statement" voltage-gated potassium channel complex ; GO:0008076 | traceable author statement integral component of membrane ; GO:0016021 | inferred from direct assay voltage-gated potassium channel complex ; GO:0008076 | non-traceable author statement voltage-gated potassium channel complex ; GO:0008076 | inferred from physical interaction with Hk "Sh, sh, EKO, SH, CG12348, V-I, Sha, Shw, CG7640, minisleep, F-c, CG17860, BcDNA:GH03046, Eko, Shaker, Kv1, sha, K[[v]]1" "IPR011333:SKP1/BTB/POZ domain, IPR000210:BTB/POZ domain, IPR003131:Potassium channel tetramerisation-type BTB domain, IPR003968:Potassium channel, voltage dependent, Kv, IPR003972:Potassium channel, voltage dependent, Kv1, IPR005821:Ion transport domain, IPR028325:Voltage-gated potassium channel, IPR004048:Potassium channel, voltage dependent, Kv1.1" CG12348 27-Aug-18 DroID_v2018_08 "Drer\LOC100004160, Drer\kcna1l, Drer\kcna4, Drer\kcna2b, Drer\knca7, Drer\si:ch73-334d15.4, Drer\LOC100330283, Drer\kcna6a, Drer\LOC100537815, Drer\kcna1a, Drer\kcna3a" - "Cele\C32C4.1, Cele\shk-1, Cele\exp-2, Cele\kvs-1, Cele\kvs-5, Cele\kvs-3, Cele\kvs-4" "Xtro\kcna3, Xtro\kcna6, Xtro\kcna7, Xtro\kcna4, Xtro\kcna1, Xtro\kcna10" "Mmus\Kcna2, Mmus\Kcna5, Mmus\Kcna6, Mmus\Kcna3, Mmus\Kcna10, Mmus\Kcna4, Mmus\Kcna7, Mmus\Kcna1" "Hsap\KCNA4, Hsap\KCNA5, Hsap\KCNA6, Hsap\KCNA7, Hsap\KCNA3, Hsap\KCNA10, Hsap\KCNA2, Hsap\KCNA1" "courtship behavior defective,viable,fertile,behavior defective,dominant,uncoordinated,short lived,neurophysiology defective,locomotor behavior defective,chemical sensitive,hyperactive,lethal,recessive,taste perception defective,smell perception defective,visible,chemical resistant,male,chemosensitive behavior defective,RU486 conditional,visual behavior defective,cold sensitive,body color defective,circadian behavior defective,sleep defective,flight defective,locomotor rhythm defective" "axon & motor neuron | conditional ts,giant fiber neuron,neuromuscular junction,synapse,end plate,photoreceptor cell,muscle fiber,wing,adult thorax,leg,embryonic/larval neuromuscular junction,photoreceptor,presumptive embryonic/larval muscle system,embryonic/larval neuron,motor neuron,eye,adult cuticle,larval head,cold sensitive,abdomen | adult stage A1,RU486 conditional" FBgn0001779 l(1)M64 lethal (1) M64 http://flybase.org/reports/FBgn0001779 - gene - - - l(1)M64 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0002290 l(3)80Fa lethal (3) 80Fa http://flybase.org/reports/FBgn0002290 - gene - - - "l8, l(3)Lh8, l(3)80Fa, 80Fa" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0038105 yellow-f2 yellow-f2 http://flybase.org/reports/FBgn0038105 protein_coding_gene dopachrome isomerase activity ; GO:0004167 | inferred from direct assay melanin biosynthetic process from tyrosine ; GO:0006583 | traceable author statement developmental pigmentation ; GO:0048066 | inferred by curator from GO:0004167 cuticle pigmentation ; GO:0048067 | inferred from biological aspect of ancestor with PANTHER:PTN000000448 melanin biosynthetic process from tyrosine ; GO:0006583 | inferred by curator from GO:0004167 developmental pigmentation ; GO:0048066 | traceable author statement indole-containing compound biosynthetic process ; GO:0042435 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay "CG8063, yellow-f2, yel-f2" "IPR017996:Major royal jelly protein/protein yellow, IPR011042:Six-bladed beta-propeller, TolB-like" CG8063 27-Aug-18 DroID_v2018_08 Drer\dpm3 - "Cele\fbxa-76, Cele\C24H12.1, Cele\F49E11.8, Cele\T27A1.3" Xtro\dpm3 Mmus\Dpm3 Hsap\DPM3 viable FBgn0031536 Cog3 Cog3 http://flybase.org/reports/FBgn0031536 protein_coding_gene protein transporter activity ; GO:0008565 | inferred from biological aspect of ancestor with PANTHER:PTN000329506 protein transporter activity ; GO:0008565 | inferred from sequence or structural similarity with UniProtKB:Q96JB2 "intracellular protein transport ; GO:0006886 | inferred from electronic annotation with InterPro:IPR007265 dsRNA transport ; GO:0033227 | inferred from mutant phenotype ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from biological aspect of ancestor with PANTHER:PTN000329506 Golgi organization ; GO:0007030 | inferred from sequence or structural similarity with UniProtKB:Q96JB2 ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from sequence or structural similarity with UniProtKB:Q96JB2 intra-Golgi vesicle-mediated transport ; GO:0006891 | inferred from sequence or structural similarity with UniProtKB:Q96JB2 male meiosis cytokinesis ; GO:0007112 | inferred from mutant phenotype retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | inferred from biological aspect of ancestor with PANTHER:PTN000329506 neurogenesis ; GO:0022008 | inferred from mutant phenotype retrograde transport, vesicle recycling within Golgi ; GO:0000301 | inferred from biological aspect of ancestor with PANTHER:PTN000329506" membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR007265 cis-Golgi network ; GO:0005801 | inferred from electronic annotation with InterPro:IPR007265 Golgi transport complex ; GO:0017119 | inferred from sequence or structural similarity with UniProtKB:Q96JB2 Golgi transport complex ; GO:0017119 | inferred from direct assay "Cog3, CG3248, dCOG3, CG 3248, COG3, SEC34" "IPR007265:Conserved oligomeric Golgi complex, subunit 3" CG3248 27-Aug-18 DroID_v2018_08 Drer\cog3 Scer\COG3 Cele\cogc-3 Xtro\cog3 Mmus\Cog3 Hsap\COG3 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC00585 E 0.517332493 0.604583619 1.787207642 -1.055849886 0.306363113 0.396189865 FBgn0034264 Dlish Dachs ligand with SH3s http://flybase.org/reports/FBgn0034264 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:M9MRE4 - apical cortex ; GO:0045179 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG10933, Dlish" IPR001452:SH3 domain CG10933 27-Aug-18 DroID_v2018_08 Drer\arhgef38 - Cele\C26C6.8 Xtro\arhgef38 Mmus\Grap "Hsap\ARHGEF38, Hsap\GRAP" "lethal,partially lethal - majority die,visible,recessive" "chaeta,supernumerary,trichogen cell,mesothoracic tergum" FBgn0005040 E(tuh-1) Enhancer of tumorous head 1 http://flybase.org/reports/FBgn0005040 - gene - - - E(tuh-1) - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004129 l(2)43Cc lethal (2) 43Cc http://flybase.org/reports/FBgn0004129 - gene - - - l(2)43Cc - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0015318 U2af65 U2 small nuclear riboprotein auxiliary factor 65 http://flybase.org/reports/FBgn0015318 FBgn0012029 gene poly-pyrimidine tract binding ; GO:0008187 | inferred from direct assay - - "U2AF, U2AF[65], U2af65" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0046888 CG31750 - http://flybase.org/reports/FBgn0046888 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | non-traceable author statement taste receptor activity ; GO:0008527 | NOT inferred from sequence or structural similarity biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG31750, Gr36d" - CG31750 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0033404 Or45a Odorant receptor 45a http://flybase.org/reports/FBgn0033404 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a "CG1978, 45a, DOR58, 45C.1, Or45a" "IPR004117:Olfactory receptor, insect" CG1978 27-Aug-18 DroID_v2018_08 - - - - - - smell perception defective FBgn0028712 MI02 MI02 http://flybase.org/reports/FBgn0028712 gene - - - "v(3)03847, MI02" - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive" FBgn0027845 Bro::Hsap\MYH11 Bro::Hsap\MYH11 http://flybase.org/reports/FBgn0027845 - engineered_fusion_gene - - - "Bro::SMMHC, Bro::Hsap\MYH11" - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "eye,ommatidium" FBgn0035547 CG15022 - http://flybase.org/reports/FBgn0035547 protein_coding_gene - - - "BcDNA:RE24507, CG15022" - CG15022 27-Aug-18 DroID_v2018_08 Drer\and3 - - - - - viable DRSC08476 IEK 0.144866205 -2.179511784 0.285832959 -2.084503675 -2.153266597 -0.980194736 FBgn0267892 CR46180 - http://flybase.org/reports/FBgn0267892 pseudogene_attribute - - - "CR46180, CG12717-related" - CR46180 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034501 CG13868 - http://flybase.org/reports/FBgn0034501 protein_coding_gene - sleep ; GO:0030431 | inferred from expression pattern - "anon-WO0153538.60, CG13868" - CG13868 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible" mesothoracic tergum FBgn0066075 Su(rux)2B Su(rux)2B http://flybase.org/reports/FBgn0066075 gene - second mitotic wave involved in compound eye morphogenesis ; GO:0016330 | non-traceable author statement - Su(rux)2B - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032029 CG17292 - http://flybase.org/reports/FBgn0032029 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from electronic annotation with InterPro:IPR000734 lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR033906 cytosol ; GO:0005829 | inferred from direct assay CG17292 "IPR000734:Triacylglycerol lipase family, IPR013818:Lipase/vitellogenin, IPR033906:Lipase, N-terminal, IPR029058:Alpha/Beta hydrolase fold" CG17292 27-Aug-18 DroID_v2018_08 "Drer\lipca, Drer\LOC101884800, Drer\LOC100331214, Drer\lipib, Drer\lipia, Drer\lipg, Drer\lpl, Drer\pla1a" - "Cele\clec-97, Cele\clec-110, Cele\clec-203, Cele\clec-103, Cele\clec-106, Cele\clec-245, Cele\ZK39.9, Cele\clec-246, Cele\clec-99, Cele\clec-95, Cele\clec-128, Cele\clec-144, Cele\clec-127, Cele\clec-118, Cele\F17B5.10, Cele\clec-241, Cele\clec-234, Cele\clec-208, Cele\clec-259, Cele\clec-122, Cele\clec-213, Cele\clec-243, Cele\clec-244, Cele\clec-132, Cele\clec-96, Cele\clec-109, Cele\clec-121, Cele\clec-261, Cele\clec-94, Cele\clec-242" "Xtro\lipg, Xtro\lpl" "Mmus\Liph, Mmus\Pla1a, Mmus\Lpl, Mmus\Pnlip, Mmus\Pnliprp2, Mmus\Pnliprp1, Mmus\Lipi, Mmus\Lipc, Mmus\Lipg" "Hsap\LIPH, Hsap\PLA1A, Hsap\PNLIP, Hsap\LIPG, Hsap\PNLIPRP2, Hsap\LPL, Hsap\LIPC, Hsap\PNLIPRP3, Hsap\PNLIPRP1, Hsap\LIPI" viable FBgn0033756 CG17760 - http://flybase.org/reports/FBgn0033756 protein_coding_gene GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR000654 G-protein beta/gamma-subunit complex binding ; GO:0031683 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 GTPase activity ; GO:0003924 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 G-protein coupled receptor binding ; GO:0001664 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 signal transducer activity ; GO:0004871 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 adenylate cyclase-modulating G-protein coupled receptor signaling pathway ; GO:0007188 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 phospholipase C-activating dopamine receptor signaling pathway ; GO:0060158 | inferred from biological aspect of ancestor with PANTHER:PTN000026396 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with RGDID:619749 heterotrimeric G-protein complex ; GO:0005834 | inferred from biological aspect of ancestor with PANTHER:PTN000026392 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with RGDID:619749 "BcDNA:SD21019, CG17760, GNAQ/11/14" "IPR000654:G-protein alpha subunit, group Q, IPR001019:Guanine nucleotide binding protein (G-protein), alpha subunit, IPR011025:G protein alpha subunit, helical insertion, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG17760 27-Aug-18 DroID_v2018_08 "Drer\gnaq, Drer\gna15.2, Drer\gnai2b, Drer\gnat2, Drer\gna11b, Drer\gna15.1, Drer\gnai1, Drer\gna14, Drer\gnai3, Drer\gnao1b, Drer\gna15.4, Drer\gnaz, Drer\gnao1a, Drer\gnav1, Drer\gna14a, Drer\si:ch211-207c7.2, Drer\gna11a, Drer\gnaia, Drer\gnat1" "Scer\GPA1, Scer\GPA2" "Cele\egl-30, Cele\gpa-3, Cele\gpa-7, Cele\odr-3, Cele\gpa-2, Cele\gpa-16, Cele\gpa-1, Cele\gpa-4, Cele\goa-1" "Xtro\gnao1, Xtro\gnai3, Xtro\gna11, Xtro\gnai1, Xtro\gnaq, Xtro\gna14, Xtro\gna15, Xtro\gnat1, Xtro\gnat2, Xtro\gnai2" "Mmus\Gnai3, Mmus\Gnaq, Mmus\Gnaz, Mmus\Gnat2, Mmus\Gnat3, Mmus\Gnao1, Mmus\Gnai1, Mmus\Gna11, Mmus\Gnat1, Mmus\Gna14, Mmus\Gna15, Mmus\Gnai2" "Hsap\GNAT1, Hsap\GNAT2, Hsap\GNAI2, Hsap\GNA15, Hsap\GNAQ, Hsap\GNAI1, Hsap\GNAT3, Hsap\GNAZ, Hsap\GNA11, Hsap\GNA14, Hsap\GNAI3, Hsap\GNAO1" viable DRSC06694 E -0.065895759 0.423783124 1.563835556 0.936346256 -0.037558357 0.284170681 FBgn0266470 pinenut - http://flybase.org/reports/FBgn0266470 gene - - - "pinenut, pine nut" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal "egg chamber,somatic clone,oocyte associated follicular epithelium,follicle cell" FBgn0083054 snoRNA:Psi18S-1347a snoRNA:Psi18S-1347a http://flybase.org/reports/FBgn0083054 snoRNA_gene - - - "snoRNA:Psi18S-1347a, Psi18S-1347a, psi18S-1347a, Psi 18S-1347a(SnoR203), CR34544" - CR34544 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267098 asRNA:CR45538 - http://flybase.org/reports/FBgn0267098 non_protein_coding_gene - - - CR45538 - CR45538 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032588 CG5968 - http://flybase.org/reports/FBgn0032588 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT27976, CG5968" IPR031957:Domain of unknown function DUF4777 CG5968 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0003491 sps spastic http://flybase.org/reports/FBgn0003491 - gene - - - sps - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,sterile,uncoordinated,behavior defective" FBgn0041782 S(Sev-CycE)D30 S(Sev-CycE)D30 http://flybase.org/reports/FBgn0041782 gene - - - S(Sev-CycE)D30 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0035679 CG10467 - http://flybase.org/reports/FBgn0035679 protein_coding_gene "carbohydrate binding ; GO:0030246 | inferred from electronic annotation with InterPro:IPR011013, InterPro:IPR014718 aldose 1-epimerase activity ; GO:0004034 | inferred from biological aspect of ancestor with PANTHER:PTN000009552" glucose metabolic process ; GO:0006006 | inferred from biological aspect of ancestor with PANTHER:PTN000009552 galactose catabolic process via UDP-galactose ; GO:0033499 | inferred from biological aspect of ancestor with PANTHER:PTN000009552 extracellular region ; GO:0005576 | inferred from direct assay CG10467 "IPR008183:Aldose 1-/Glucose-6-phosphate 1-epimerase, IPR011013:Galactose mutarotase-like domain, IPR018052:Aldose 1-epimerase, conserved site, IPR014718:Glycoside hydrolase-type carbohydrate-binding, IPR015443:Aldose 1-epimerase" CG10467 27-Aug-18 DroID_v2018_08 Drer\galm "Scer\YHR210C, Scer\GAL10, Scer\YNR071C" "Cele\Y19D10A.16, Cele\C01B4.6" Xtro\galm Mmus\Galm Hsap\GALM viable DRSC09728 K 0.066956422 0.007044745 -0.526193059 0.660274526 -0.613578298 2.165825822 FBgn0001750 l(1)HM22 lethal (1) HM22 http://flybase.org/reports/FBgn0001750 - gene - - - l(1)HM22 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,cold sensitive,female fertile" FBgn0001370 l(1)2Ac lethal (1) 2Ac http://flybase.org/reports/FBgn0001370 FBgn0001368 gene - - - "l(1)2Aa, l(1)2Ac" - - 27-Aug-18 DroID_v2018_08 - - - - - - "cell lethal,germline clone,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0085661 CG41511 - http://flybase.org/reports/FBgn0085661 protein_coding_gene - - - CG41511 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0042691 Su(Ste)OR Suppressor of Stellate orphon http://flybase.org/reports/FBgn0042691 pseudogene_attribute - - - "SuSteOR, Su(Ste)OR" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004107 Cdk2 Cyclin-dependent kinase 2 http://flybase.org/reports/FBgn0004107 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 cyclin-dependent protein serine/threonine kinase activity ; GO:0004693 | inferred from sequence or structural similarity with SGD:S000000364 cyclin-dependent protein serine/threonine kinase activity ; GO:0004693 | inferred from biological aspect of ancestor with PANTHER:PTN000623091 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement" regulation of meiotic cell cycle ; GO:0051445 | inferred from biological aspect of ancestor with PANTHER:PTN000756019 DNA repair ; GO:0006281 | inferred from biological aspect of ancestor with PANTHER:PTN000756019 cell differentiation ; GO:0030154 | inferred from biological aspect of ancestor with PANTHER:PTN000756019 protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with SGD:S000000364 protein phosphorylation ; GO:0006468 | non-traceable author statement mitotic cell cycle phase transition ; GO:0044772 | inferred from biological aspect of ancestor with PANTHER:PTN000756019 regulation of mitotic cell cycle ; GO:0007346 | inferred from biological aspect of ancestor with PANTHER:PTN000756019 G2/M transition of mitotic cell cycle ; GO:0000086 | inferred from sequence or structural similarity with SGD:S000000364 microtubule cytoskeleton organization ; GO:0000226 | inferred from biological aspect of ancestor with PANTHER:PTN000756019 regulation of gene expression ; GO:0010468 | inferred from biological aspect of ancestor with PANTHER:PTN000756019 JAK-STAT cascade ; GO:0007259 | inferred from physical interaction with Stat92E G1/S transition of mitotic cell cycle ; GO:0000082 | inferred from sequence or structural similarity with SGD:S000000364 histone phosphorylation ; GO:0016572 | inferred from biological aspect of ancestor with PANTHER:PTN000756019 mitotic spindle ; GO:0072686 | inferred from biological aspect of ancestor with PANTHER:PTN000756019 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000756019 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000623091 microtubule associated complex ; GO:0005875 | inferred from direct assay "cdc2c, Cdk2, cdk2, CDK2, Cdc2c, CG10498, CDK2/CDC2c, S(Sev-CycE)3A, DmCdk2, Dmcdc2c, Dcdc2c, CDC2c, dCdk2, CDC2C, DmCdc2c" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG10498 27-Aug-18 DroID_v2018_08 "Drer\LOC100536316, Drer\cdk21, Drer\cdk5, Drer\cdk17, Drer\cdk15, Drer\cdk6, Drer\cdk1, Drer\cdk14, Drer\cdk2, Drer\si:dkey-166c18.1, Drer\cdk4, Drer\cdk16" "Scer\PHO85, Scer\CDC28, Scer\CAK1, Scer\CTK1" "Cele\ZC123.4, Cele\cdk-5, Cele\cdk-1, Cele\cdk-2" "Xtro\cdk18, Xtro\cdk2, Xtro\cdk1, Xtro\cdk17, Xtro\cdk15, Xtro\cdk6, Xtro\cdk16, Xtro\cdk14, Xtro\cdk4, Xtro\cdk5" "Mmus\Cdk2, Mmus\Cdk18, Mmus\Cdk5, Mmus\Cdk17, Mmus\Cdk14, Mmus\Cdk15, Mmus\Cdk6, Mmus\Cdk16, Mmus\Cdk4, Mmus\E030030I06Rik, Mmus\Cdk1" "Hsap\CDK18, Hsap\CDK15, Hsap\CDK1, Hsap\CDK5, Hsap\CDK17, Hsap\CDK3, Hsap\CDK4, Hsap\CDK6, Hsap\CDK14, Hsap\CDK16, Hsap\CDK2" " embryonic stage | early , embryonic stage " embryonic central nervous system

"small body,lethal,recessive,wild-type" larval outer optic anlage DRSC16921 IEK -1.417489246 -1.755788586 -2.638859898 -3.688672595 4.262878723 4.709982217 FBgn0034628 Acox57D-p acyl-Coenzyme A oxidase at 57D proximal http://flybase.org/reports/FBgn0034628 protein_coding_gene "acyl-CoA dehydrogenase activity ; GO:0003995 | inferred from electronic annotation with InterPro:IPR006091 flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR012258, InterPro:IPR013786 acyl-CoA oxidase activity ; GO:0003997 | inferred from sequence or structural similarity with HGNC:119" fatty acid beta-oxidation ; GO:0006635 | inferred from sequence or structural similarity with HGNC:119 "peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:119,HGNC:120 inferred from sequence model" "acox, D-acox, CG9707, Acox57Dp, Acox57D-p" "IPR002655:Acyl-CoA oxidase, C-terminal, IPR006091:Acyl-CoA oxidase/dehydrogenase, central domain, IPR009075:Acyl-CoA dehydrogenase/oxidase C-terminal, IPR009100:Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain, IPR012258:Acyl-CoA oxidase, IPR013786:Acyl-CoA dehydrogenase/oxidase, N-terminal, IPR029320:Acyl-coenzyme A oxidase, N-terminal" CG9707 27-Aug-18 DroID_v2018_08 "Drer\acox1, Drer\acox3" Scer\POX1 "Cele\acox-4, Cele\acox-1, Cele\F59F4.1, Cele\acox-5, Cele\acox-3, Cele\acox-2, Cele\acdh-13" "Xtro\acox2, Xtro\acox1" "Mmus\Acox1, Mmus\Acox2, Mmus\Acox3" "Hsap\ACOX1, Hsap\ACOX2, Hsap\ACOX3" FBgn0014868 Ost48 Oligosaccharyltransferase 48kD subunit http://flybase.org/reports/FBgn0014868 FBgn0026008 protein_coding_gene - protein N-linked glycosylation via asparagine ; GO:0018279 | inferred from electronic annotation with InterPro:IPR005013 neurogenesis ; GO:0022008 | inferred from mutant phenotype lipid particle organization ; GO:0034389 | inferred from mutant phenotype Golgi organization ; GO:0007030 | inferred from mutant phenotype endoplasmic reticulum membrane ; GO:0005789 | inferred from electronic annotation with InterPro:IPR005013 endomembrane system ; GO:0012505 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay "Ots48, CG9022, OST48/WBP1, DrOST, OST48, DmOST50, clone 1.11, anon-EST:Liang-1.11, Ost48, ost48, OST" "IPR005013:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit, IPR029062:Class I glutamine amidotransferase-like" CG9022 27-Aug-18 DroID_v2018_08 Drer\ddost Scer\WBP1 Cele\ostb-1 Xtro\ddost Mmus\Ddost Hsap\DDOST "lethal,neuroanatomy defective,partially lethal - majority die,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0001691 l(1)ESHS12 lethal (1) ESHS12 http://flybase.org/reports/FBgn0001691 - gene - - - l(1)ESHS12 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0022945 CFDD Common regulatory Factor for DNA replication and DREF genes http://flybase.org/reports/FBgn0022945 - gene DNA binding ; GO:0003677 | inferred from direct assay - nucleus ; GO:0005634 | inferred from direct assay CFDD - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0014092 CG4278 - http://flybase.org/reports/FBgn0014092 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000351096 "un5, BG:DS02740.16, anon-35F/36A, CG4278" IPR002678:GTP cyclohydrolase 1 type 2/Nif3 CG4278 27-Aug-18 DroID_v2018_08 "Drer\ciao1, Drer\nif3l1" Scer\NIF3 Cele\Y18D10A.9 "Xtro\nif3l1, Xtro\LOC101733905, Xtro\ciao1" "Mmus\Ciao1, Mmus\Nif3l1" "Hsap\CIAO1, Hsap\NIF3L1" embryonic stage | early viable FBgn0028496 CG30116 - http://flybase.org/reports/FBgn0028496 protein_coding_gene - - - "BcDNA:GH04922, CG5512, CG17671, CG30116" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR011047:Quinoprotein alcohol dehydrogenase-like superfamily, IPR017986:WD40-repeat-containing domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat" CG30116 27-Aug-18 DroID_v2018_08 "Drer\LOC101885341, Drer\nwd1" "Scer\CDC4, Scer\PRP46" "Cele\T05C3.2, Cele\qui-1" - "Mmus\Wdr27, Mmus\Ttc41, Mmus\Nwd1" "Hsap\NWD1, Hsap\WDR27" "viable,fertile" FBgn0051418 CG31418 - http://flybase.org/reports/FBgn0051418 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "CG5329, CG31418" - CG31418 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0264714 CG43982 - http://flybase.org/reports/FBgn0264714 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43982 - CG43982 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0015780 Onf-AATAA Ovarian nuclear factor-AATAA http://flybase.org/reports/FBgn0015780 - gene - - - "ONF-AATAA, Onf-AATAA" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265719 lncRNA:CR44526 - http://flybase.org/reports/FBgn0265719 non_protein_coding_gene - - - "incRNA.476, CR44526, lincRNA.476" - CR44526 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0050145 Obp57e Odorant-binding protein 57e http://flybase.org/reports/FBgn0050145 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush odorant binding ; GO:0005549 | inferred from sequence or structural similarity with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of smell ; GO:0007608 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush transport ; GO:0006810 | non-traceable author statement sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with UniProtKB:P34174 extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 extracellular region ; GO:0005576 | inferred from sequence model "CG13429, Obp57d, 57e, OBP57e, CG30145, Obp57e, Dmel\Obp57e, DmelObp57e" IPR006170:Pheromone/general odorant binding protein CG30145 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0040103 lectin-24Da lectin-24Da http://flybase.org/reports/FBgn0040103 gene galactose binding ; GO:0005534 | inferred from sequence or structural similarity - - "AC004279a, AC 004279A, lectin-24Da" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000373 cripB crippled B http://flybase.org/reports/FBgn0000373 - gene - - - cripB - - 27-Aug-18 DroID_v2018_08 - - - - - - "hypoactive,visible,uncoordinated" eye FBgn0250837 dUTPase Deoxyuridine triphosphatase http://flybase.org/reports/FBgn0250837 protein_coding_gene dUTP diphosphatase activity ; GO:0004170 | inferred from direct assay dUTP metabolic process ; GO:0046080 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG4584, LD08534, BcDNA:LD08534, UTPase, dUTPase, anon-SAGE:Wang-077" "IPR008181:Deoxyuridine triphosphate nucleotidohydrolase, IPR029054:dUTPase-like, IPR033704:dUTPase, trimeric" CG4584 27-Aug-18 DroID_v2018_08 Drer\dut Scer\DUT1 Cele\dut-1 Xtro\dut Mmus\Dut "Hsap\LOC100506422, Hsap\DUT" FBgn0013566 l(3)78Ab lethal (3) 78Ab http://flybase.org/reports/FBgn0013566 - gene - - - l(3)78Ab - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0011808 l(3)s2714 lethal (3) s2714 http://flybase.org/reports/FBgn0011808 - gene - - - l(3)s2714 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0005680 disf disordered facets http://flybase.org/reports/FBgn0005680 - gene - compound eye development ; GO:0048749 | inferred from mutant phenotype - "disf, dif" - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive" "eye,ommatidium,eye photoreceptor cell,supernumerary,retina" FBgn0265043 asRNA:CR44160 - http://flybase.org/reports/FBgn0265043 non_protein_coding_gene - - - CR44160 - CR44160 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0011630 l(2)T57d12 lethal (2) T57d12 http://flybase.org/reports/FBgn0011630 FBgn0005177 gene - - - l(2)T57d12 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0037944 CG6923 - http://flybase.org/reports/FBgn0037944 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN000280277 zinc ion binding ; GO:0008270 | inferred from sequence model proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN000280277 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN000280277 protein polyubiquitination ; GO:0000209 | inferred from biological aspect of ancestor with PANTHER:PTN000280277 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN001102293 CG6923 "IPR001841:Zinc finger, RING-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG6923 27-Aug-18 DroID_v2018_08 "Drer\rnf111, Drer\rnf115, Drer\rnf150, Drer\rnf24, Drer\zswim2, Drer\rnf165b, Drer\rnf11a, Drer\znrf3, Drer\rnf6, Drer\si:ch1073-392o20.1, Drer\zgc:175214, Drer\rnf165a, Drer\si:ch211-81a5.1, Drer\rnf130, Drer\rnf103, Drer\rlim, Drer\si:dkey-51a16.9, Drer\rnf150a, Drer\rnf126, Drer\rnf38, Drer\rnf215, Drer\rnf11b, Drer\rnf32, Drer\rnf44, Drer\wu:fb39e10, Drer\pja2" "Scer\ASR1, Scer\YBR062C" "Cele\Y73C8C.8, Cele\C09E7.7, Cele\sdz-34, Cele\Y73C8C.3, Cele\toe-4, Cele\T22B2.1" "Xtro\rnf126, Xtro\rnf32, Xtro\rnf11.2, Xtro\pja2, Xtro\rnf111, Xtro\rnf149, Xtro\chmp3, Xtro\rnf181, Xtro\rnf11, Xtro\rnf44, Xtro\rlim, Xtro\rnf24, Xtro\znrf3, Xtro\rnf38, Xtro\rnf115" "Mmus\Rnf149, Mmus\Rnf43, Mmus\Rlim, Mmus\Rnf38, Mmus\Pja1, Mmus\Rnf44, Mmus\Zswim2, Mmus\Rnf11, Mmus\Rnf122, Mmus\Rnf103, Mmus\Rnf24, Mmus\Rnf126, Mmus\Rnf32, Mmus\Rnf165, Mmus\4930595M18Rik, Mmus\Rnf215, Mmus\Znrf3, Mmus\Rnf115, Mmus\Rnf6, Mmus\Pja2, Mmus\Rnf150, Mmus\Rnf130, Mmus\Rnf111, Mmus\Rnf181, Mmus\Rnf148" "Hsap\ZSWIM2, Hsap\RNF130, Hsap\PJA2, Hsap\RNF165, Hsap\RNF43, Hsap\RNF44, Hsap\RNF115, Hsap\RNF148, Hsap\RNF149, Hsap\RNF103, Hsap\RLIM, Hsap\RNF122, Hsap\RNF38, Hsap\RNF126, Hsap\CHMP3, Hsap\ZNRF3, Hsap\RNF150, Hsap\RNF32, Hsap\RNF11, Hsap\RNF111, Hsap\PJA1, Hsap\RNF24, Hsap\RNF215, Hsap\RNF181, Hsap\RNF6" viable FBgn0265185 CG44250 - http://flybase.org/reports/FBgn0265185 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG3884, CG44250" "IPR024518:Domain of unknown function DUF3421, IPR006616:DM9 repeat" CG44250 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0011965 tRNA:Arg-TCG-4-1 transfer RNA:Arginine-TCG 4-1 http://flybase.org/reports/FBgn0011965 "FBgn0011947, FBgn0051593, FBgn0060077" tRNA_gene CGA codon-amino acid adaptor activity ; GO:0033431 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033431 cytosol ; GO:0005829 | inferred by curator from GO:0033431 "tRNA-Arg, tRNA[arg], AE002681.trna1-ArgTCG, tRNA:R1, tRNA:arg1, tRNA:R:TCG:AE002681, CR31593, tRNA:arg83AB, chr3R.trna1-ArgTCG, tRNA-Arg-TCG-4-1, tRNA:Arg-TCG-4-1, tRNA:R:83AB, CGA" - CR31593 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001787 l(1)M96 lethal (1) M96 http://flybase.org/reports/FBgn0001787 - gene - - - l(1)M96 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0052522 CG32522 - http://flybase.org/reports/FBgn0052522 protein_coding_gene - - - CG32522 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032909 CG9266 - http://flybase.org/reports/FBgn0032909 protein_coding_gene - - - "BcDNA:GM06547, CG9266" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0026385 Or47b Odorant receptor 47b http://flybase.org/reports/FBgn0026385 - protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from direct assay odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | non-traceable author statement detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from direct assay sensory perception of smell ; GO:0007608 | non-traceable author statement integral component of membrane ; GO:0016021 | non-traceable author statement dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 "CG13206, 47b, Or47E.2, DOR25, 47E.2, DOR47E.2, Or47b, OR 47b, OR47b, or47b" "IPR004117:Olfactory receptor, insect" CG13206 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0000597 E(var)87F Enhancer of variegation 3 http://flybase.org/reports/FBgn0000597 FBgn0000598 gene - - - "E-var(3)3, E(var)8, E(var)3-3, E(var)3, E(var)87F" - - 27-Aug-18 DroID_v2018_08 - - - - - - "enhancer of variegation,dominant" FBgn0263481 snoRNA:lola-b - http://flybase.org/reports/FBgn0263481 snoRNA_gene - - - snoRNA:lola-b - CR43596 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000146 aub aubergine http://flybase.org/reports/FBgn0000146 "FBgn0010310, FBgn0024835" protein_coding_gene RNA binding ; GO:0003723 | inferred from direct assay piRNA binding ; GO:0034584 | inferred from direct assay "karyosome formation ; GO:0030717 | traceable author statement positive regulation of nuclear-transcribed mRNA poly(A) tail shortening ; GO:0060213 | inferred from mutant phenotype positive regulation of innate immune response ; GO:0045089 | inferred from mutant phenotype RNA interference ; GO:0016246 | traceable author statement RNA interference ; GO:0016246 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype pole cell formation ; GO:0007279 | inferred from genetic interaction with tud inferred from genetic interaction with vas regulation of pole plasm oskar mRNA localization ; GO:0007317 | inferred from mutant phenotype oogenesis ; GO:0048477 | traceable author statement mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 oogenesis ; GO:0048477 | inferred from mutant phenotype mitotic chromosome condensation ; GO:0007076 | inferred from mutant phenotype pole cell formation ; GO:0007279 | inferred from genetic interaction with osk regulation of oskar mRNA translation ; GO:0046011 | traceable author statement oocyte maturation ; GO:0001556 | inferred from mutant phenotype targeting of mRNA for destruction involved in RNA interference ; GO:0030423 | inferred from mutant phenotype negative regulation of transposition ; GO:0010529 | inferred from mutant phenotype chromatin silencing ; GO:0006342 | inferred from mutant phenotype positive regulation of oskar mRNA translation ; GO:0046012 | traceable author statement maintenance of pole plasm mRNA location ; GO:0046594 | traceable author statement pole plasm protein localization ; GO:0007318 | inferred from mutant phenotype regulation of translational initiation ; GO:0006446 | inferred from sequence or structural similarity with protein_id:AAC24323.1 positive regulation of oskar mRNA translation ; GO:0046012 | non-traceable author statement dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype segmentation ; GO:0035282 | inferred from genetic interaction with nos" P granule ; GO:0043186 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay "aub, sting, sti, ms(2)32D, CG6137, AUB, Aub, aubergine" "IPR012337:Ribonuclease H-like domain, IPR003100:PAZ domain, IPR003165:Piwi domain" CG6137 27-Aug-18 DroID_v2018_08 "Drer\ago3b, Drer\piwil2, Drer\ago1, Drer\LOC567622, Drer\ago2, Drer\piwil1" - "Cele\hpo-24, Cele\alg-3, Cele\alg-1, Cele\prg-2, Cele\prg-1, Cele\rde-1" "Xtro\piwil1, Xtro\ago2, Xtro\piwil3, Xtro\ago4, Xtro\piwil2, Xtro\piwil4, Xtro\ago3" "Mmus\Ago3, Mmus\Piwil4, Mmus\Ago2, Mmus\Piwil2, Mmus\Ago1, Mmus\Piwil1, Mmus\Ago4" "Hsap\AGO2, Hsap\PIWIL4, Hsap\AGO1, Hsap\AGO3, Hsap\AGO4, Hsap\PIWIL3, Hsap\PIWIL1, Hsap\PIWIL2" " adult stage | female , adult stage | male " " ovary

, testis

" "lethal,maternal effect,recessive,female sterile,mitotic cell cycle defective,female,lethal - all die before end of embryonic stage,male sterile,wild-type,non-rescuable maternal effect,some die during embryonic stage,suppressor of variegation,non-suppressor of variegation,dominant,viable" "embryo,maternal effect,posterior,dorsal appendage,chorion,female germline stem cell,cystoblast,embryonic/larval cuticle,spermatocyte,spermatid,karyosome" FBgn0262213 mir-2495 mir-2495 stem loop http://flybase.org/reports/FBgn0262213 miRNA_gene - - - "mir-2495, CR42920, dme-mir-2495, miR-2495" - CR42920 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0032597 CG17904 - http://flybase.org/reports/FBgn0032597 protein_coding_gene "4 iron, 4 sulfur cluster binding ; GO:0051539 | inferred from electronic annotation with InterPro:IPR028601 iron-sulfur cluster binding ; GO:0051536 | inferred from sequence or structural similarity with UniProtKB:P53384" iron-sulfur cluster assembly ; GO:0016226 | inferred from sequence or structural similarity with UniProtKB:P53384 cytosol ; GO:0005829 | inferred from sequence or structural similarity with UniProtKB:P53384 "CG17904, Nubp1" "IPR019591:Mrp/NBP35 ATP-binding protein, IPR033756:Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35, IPR028601:Cytosolic Fe-S cluster assembly factor NUBP1/Nbp35, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG17904 27-Aug-18 DroID_v2018_08 "Drer\nubp2, Drer\nubpl, Drer\nubp1" "Scer\CFD1, Scer\NBP35" Cele\nubp-1 "Xtro\nubp1, Xtro\nubp2, Xtro\nubpl" "Mmus\Nubpl, Mmus\Nubp2, Mmus\Nubp1" "Hsap\NUBP1, Hsap\NUBPL, Hsap\NUBP2" viable FBgn0044824 R1A1-element\ORF2 R1A1-element ORF2 http://flybase.org/reports/FBgn0044824 transposable_element_gene - - - "R1, R1A1-element\ORF2, R1-element\ORF2" "IPR000477:Reverse transcriptase domain, IPR005135:Endonuclease/exonuclease/phosphatase" - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0012038 Antp::Scr Antp::Scr http://flybase.org/reports/FBgn0012038 - engineered_fusion_gene - - - Antp::Scr - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,heat sensitive" "head,T1 beard,ectopic,mesothoracic segment,metathoracic segment,arista,tarsal segment,eye,occiput,prothoracic segment,metatarsus,third segment of antenna,heat sensitive,femur,embryonic head,adult head,antenna,embryonic/larval salivary gland,thoracic segment,denticle,mesothoracic leg" FBgn0035268 CG8001 - http://flybase.org/reports/FBgn0035268 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:24891 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:24891 CG8001 "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG8001 27-Aug-18 DroID_v2018_08 "Drer\dcaf6, Drer\dcaf8, Drer\wdtc1" Scer\COP1 "Cele\npp-23, Cele\R11D1.1, Cele\adpr-1" "Xtro\dcaf6, Xtro\dcaf8" "Mmus\Dcaf8, Mmus\Wdtc1, Mmus\Dcaf6, Mmus\Pet2" "Hsap\DCAF6, Hsap\DCAF8L1, Hsap\WDTC1, Hsap\DCAF8L2, Hsap\DCAF8" viable FBgn0030340 CG15740 - http://flybase.org/reports/FBgn0030340 protein_coding_gene - - - "i175, CG15740" IPR015943:WD40/YVTN repeat-like-containing domain CG15740 27-Aug-18 DroID_v2018_08 - - - "Xtro\uspl1, Xtro\LOC100494818" - - "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC23079 K 3.84774172 -0.800226233 FBgn0050389 CG30389 - http://flybase.org/reports/FBgn0050389 protein_coding_gene - - integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR019130 "CG4126, CG10518, BcDNA:AT02070, CG30389" "IPR019130:Macoilin, IPR015943:WD40/YVTN repeat-like-containing domain" CG30389 27-Aug-18 DroID_v2018_08 "Drer\tmem57b, Drer\si:dkey-12h9.6, Drer\tmem57a" - Cele\maco-1 Xtro\tmem57 Mmus\Tmem57 Hsap\TMEM57 "viable,fertile,visible" "trichogen cell,mesothoracic tergum" FBgn0000282 cel celibate http://flybase.org/reports/FBgn0000282 - gene - copulation ; GO:0007620 | non-traceable author statement male courtship behavior ; GO:0008049 | traceable author statement - cel - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,mating defective,male" FBgn0032717 CG10600 - http://flybase.org/reports/FBgn0032717 protein_coding_gene - - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR026306 CG10600 IPR026306:Round spermatid basic protein 1 CG10600 27-Aug-18 DroID_v2018_08 Drer\LOC100330644 - Cele\dpy-21 "Xtro\rsbn1, Xtro\rsbn1l" "Mmus\Rsbn1, Mmus\Rsbn1l" "Hsap\RSBN1L, Hsap\RSBN1" "viable,fertile" FBgn0052532 CG32532 - http://flybase.org/reports/FBgn0052532 protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR017970" - "CG14203, CG14202, CG14201, CG32532" "IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR017970:Homeobox, conserved site, IPR011989:Armadillo-like helical, IPR015943:WD40/YVTN repeat-like-containing domain" CG32532 27-Aug-18 DroID_v2018_08 "Drer\hoxa2b, Drer\hoxc9a, Drer\hoxb1a, Drer\hoxa9b, Drer\hoxa9a, Drer\hoxb6b, Drer\arxa, Drer\msx1b, Drer\prop1, Drer\hoxd9a, Drer\hoxb1b, Drer\hoxb9a, Drer\hesx1" Scer\PHO2 "Cele\unc-42, Cele\pax-3, Cele\mls-2" "Xtro\hoxb9, Xtro\hoxa1, Xtro\tlx1, Xtro\hoxd9, Xtro\hoxa5, Xtro\hoxa3, Xtro\hesx1" "Mmus\Cdx4, Mmus\Hoxb1, Mmus\Dlx3, Mmus\Hoxb3, Mmus\Hoxc9, Mmus\Hoxd9, Mmus\Hoxa9, Mmus\Barx2, Mmus\Prop1, Mmus\Hoxb9, Mmus\Tlx2, Mmus\Nanog, Mmus\Hesx1" "Hsap\HOXD9, Hsap\HOXB3, Hsap\HOXB9, Hsap\CDX4, Hsap\NKX2-8, Hsap\HOXA3, Hsap\HESX1, Hsap\PAX4, Hsap\HOXA5, Hsap\DLX4, Hsap\HOXA9, Hsap\HOXC9, Hsap\BARX2, Hsap\PROP1, Hsap\HOXB1, Hsap\HOXA1, Hsap\MSX1" "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC19556 K 0.405889417 0.556868105 -0.462647501 0.559554584 -0.317812098 -1.51757777 FBgn0263565 mir-4950 mir-4950 stem loop http://flybase.org/reports/FBgn0263565 miRNA_gene - - - "mir-4950, dme-mir-4950, CR43550" - CR43550 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0028402 Sin Sex-lethal interactor http://flybase.org/reports/FBgn0028402 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Sxl RNA polymerase III activity ; GO:0001056 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000249148 "transcription, DNA-templated ; GO:0006351 | inferred from electronic annotation with InterPro:IPR006886" DNA-directed RNA polymerase III complex ; GO:0005666 | inferred from biological aspect of ancestor with PANTHER:PTN000249148 "sin, CG10582, Sin" IPR006886:DNA-directed RNA polymerase III subunit Rpc5 CG10582 27-Aug-18 DroID_v2018_08 Drer\polr3e Scer\RPC37 Cele\W06E11.1 Xtro\polr3e Mmus\Polr3e "Hsap\LOC101060521, Hsap\POLR3E" " embryonic stage , embryonic stage | early "

ubiquitous lethal DRSC11880 E -0.669581338 0.830418859 -2.141370535 -0.50721451 -0.784533209 -0.254867776 FBgn0039196 CG17781 - http://flybase.org/reports/FBgn0039196 protein_coding_gene - - - CG17781 IPR006631:Protein of unknown function DM4/12 CG17781 27-Aug-18 DroID_v2018_08 - - - - - - DRSC15266 K 0.33721108 -0.132658862 -0.140628841 0.289813216 0.079074587 2.121301381 FBgn0036454 CG17839 - http://flybase.org/reports/FBgn0036454 protein_coding_gene - - nucleus ; GO:0005634 | inferred from direct assay "CT39634, CG17839, 17839" "IPR002602:Domain of unknown function DB, IPR003599:Immunoglobulin subtype, IPR003961:Fibronectin type III, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR013151:Immunoglobulin, IPR003598:Immunoglobulin subtype 2" CG17839 27-Aug-18 DroID_v2018_08 - Scer\OPY2 "Cele\igdb-2, Cele\wrk-1, Cele\igdb-3, Cele\igdb-1" - - - "viable,fertile" FBgn0033807 AQP aquaporin http://flybase.org/reports/FBgn0033807 protein_coding_gene - - cellular_component ; GO:0005575 | no biological data available "AQP-dr, CG12251, AQP, Aqp 12L" "IPR016697:Aquaporin 11/12, IPR023271:Aquaporin-like, IPR031145:Invertebrate aquaporin-10" CG12251 27-Aug-18 DroID_v2018_08 "Drer\aqp11, Drer\aqp12" - "Cele\aqp-10, Cele\aqp-9, Cele\aqp-11" - "Mmus\Aqp12, Mmus\Aqp11" "Hsap\AQP11, Hsap\AQP12B, Hsap\AQP12A" FBgn0261729 EC1608 - http://flybase.org/reports/FBgn0261729 gene - - - EC1608 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0030654 CG15643 - http://flybase.org/reports/FBgn0030654 protein_coding_gene - - - "CG32583, CG15643" IPR019352:Uncharacterised protein family UPF0454 CG15643 27-Aug-18 DroID_v2018_08 Drer\zgc:110063 - - Xtro\c12orf49 Mmus\2410131K14Rik Hsap\C12orf49 FBgn0039850 CG11333 - http://flybase.org/reports/FBgn0039850 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR000868 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR000868 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001797383 "BcDNA:AT02774, CG11333" IPR000868:Isochorismatase-like CG11333 27-Aug-18 DroID_v2018_08 "Drer\isoc2, Drer\isoc1" - Cele\marb-1 "Xtro\isoc2, Xtro\isoc1" "Mmus\Isoc2a, Mmus\Isoc1, Mmus\Isoc2b" "Hsap\ISOC2, Hsap\ISOC1" viable FBgn0002655 mat(2)cell-D maternal effect cellularisation defect D http://flybase.org/reports/FBgn0002655 - gene molecular_function ; GO:0003674 | no biological data available cellularization ; GO:0007349 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "mat(2)cellPQ49, mat(2)cell-D" - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "stage 5 embryo,maternal effect,embryonic/first instar larval cuticle" FBgn0266399 lncRNA:CR45039 - http://flybase.org/reports/FBgn0266399 non_protein_coding_gene - - - CR45039 - CR45039 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034187 CG6967 - http://flybase.org/reports/FBgn0034187 protein_coding_gene - - - "CT21565, CG6967" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR026127:Probable RNA helicase SDE3" CG6967 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-97a13.6, Drer\mov10b.2, Drer\znfx1, Drer\mov10b.1, Drer\mov10a, Drer\zgc:154086, Drer\helz2" "Scer\HCS1, Scer\NAM7" "Cele\eri-7, Cele\ZK1067.2" "Xtro\mov10l1, Xtro\mov10, Xtro\helz" "Mmus\Znfx1, Mmus\Helz, Mmus\Mov10, Mmus\Mov10l1, Mmus\Helz2" "Hsap\HELZ, Hsap\HELZ2, Hsap\ZNFX1, Hsap\MOV10L1, Hsap\MOV10" "viable,fertile" FBgn0063647 CE2-2 "Calcineurin enhancer, chromosome 2, group 2" http://flybase.org/reports/FBgn0063647 gene - - - CE2-2 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0022366 Pt-7 Larval protein-7 http://flybase.org/reports/FBgn0022366 - gene - - - Pt-7 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265194 Trpm "Transient receptor potential cation channel, subfamily M" http://flybase.org/reports/FBgn0265194 protein_coding_gene "cation channel activity ; GO:0005261 | inferred from direct assay intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity ; GO:0097682 | inferred from direct assay metal ion transmembrane transporter activity ; GO:0046873 | inferred from direct assay" protein tetramerization ; GO:0051262 | inferred from electronic annotation with InterPro:IPR032415 divalent metal ion transport ; GO:0070838 | inferred from direct assay zinc ion homeostasis ; GO:0055069 | inferred from mutant phenotype cell growth ; GO:0016049 | inferred from mutant phenotype magnesium ion homeostasis ; GO:0010960 | inferred from mutant phenotype cation transmembrane transport ; GO:0098655 | inferred from direct assay mitochondrion organization ; GO:0007005 | inferred from mutant phenotype thermotaxis ; GO:0043052 | NOT inferred from mutant phenotype cation channel complex ; GO:0034703 | inferred from direct assay "CG44240, Trpm, trpm, CG34187, CG34123, CG30079, CG30078, TrpM, TRPM, CG16805, BcDNA:GH04950, dTRPM, DmTRPM, mdcds_11815" "IPR005821:Ion transport domain, IPR020683:Ankyrin repeat-containing domain, IPR032415:TRPM, tetramerisation domain" CG44240 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-173d10.1, Drer\trpm4b.1, Drer\trpm5, Drer\trpm7, Drer\trpm4b.2, Drer\trpm2, Drer\trpm6, Drer\trpm4a, Drer\trpm3, Drer\trpm1a, Drer\trpm1b" - "Cele\trpl-2, Cele\gtl-2, Cele\trpl-4, Cele\F13B12.3, Cele\trpl-3, Cele\gon-2, Cele\trpl-5, Cele\gtl-1" "Xtro\trpm6, Xtro\trpm3, Xtro\trpm8, Xtro\LOC100491139, Xtro\trpm4, Xtro\trpm1, Xtro\trpm7" "Mmus\Trpm1, Mmus\Trpm5, Mmus\Trpm3, Mmus\Trpm2, Mmus\Trpm7, Mmus\Trpm6, Mmus\Trpm4, Mmus\Trpm8" "Hsap\TRPM5, Hsap\TRPM3, Hsap\TRPM1, Hsap\TRPM4, Hsap\TRPM7, Hsap\TRPM6, Hsap\TRPM2, Hsap\TRPM8" FBgn0085235 CG34206 - http://flybase.org/reports/FBgn0085235 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34206 - CG34206 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038950 CG5382 - http://flybase.org/reports/FBgn0038950 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model dsRNA transport ; GO:0033227 | inferred from mutant phenotype endomembrane system ; GO:0012505 | inferred from direct assay CG5382 "IPR001841:Zinc finger, RING-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG5382 27-Aug-18 DroID_v2018_08 Drer\zfpl1 - Cele\Y45G12B.2 Xtro\zfpl1 Mmus\Zfpl1 Hsap\ZFPL1 FBgn0017391 l(1)15Bc lethal (1) 15Bc http://flybase.org/reports/FBgn0017391 - gene - - - l(1)15Bc - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0052232 CG32232 - http://flybase.org/reports/FBgn0052232 protein_coding_gene gamma-tubulin binding ; GO:0043015 | inferred from electronic annotation with InterPro:IPR007259 molecular_function ; GO:0003674 | no biological data available microtubule nucleation ; GO:0007020 | inferred from electronic annotation with InterPro:IPR007259 spindle pole ; GO:0000922 | inferred from electronic annotation with InterPro:IPR007259 microtubule organizing center ; GO:0005815 | inferred from electronic annotation with InterPro:IPR007259 CG32232 IPR007259:Gamma-tubulin complex component protein CG32232 27-Aug-18 DroID_v2018_08 "Drer\tubgcp6, Drer\tubgcp5" - Cele\droe-4 "Xtro\tubgcp5, Xtro\tubgcp6" "Mmus\Tubgcp6, Mmus\Tubgcp5" Hsap\TUBGCP5 viable FBgn0036782 CG7320 - http://flybase.org/reports/FBgn0036782 protein_coding_gene - - - CG7320 "IPR014756:Immunoglobulin E-set, IPR013788:Hemocyanin/hexamerin, IPR005204:Hemocyanin, N-terminal, IPR000896:Hemocyanin/hexamerin middle domain, IPR008922:Uncharacterised domain, di-copper centre, IPR005203:Hemocyanin, C-terminal" CG7320 27-Aug-18 DroID_v2018_08 - - "Cele\C49A9.3, Cele\F58F9.4, Cele\C49A9.2" - - - FBgn0001885 l(2)21Bb lethal (2) 21Bb http://flybase.org/reports/FBgn0001885 - gene - - - l(2)21Bb - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0036593 CG13048 - http://flybase.org/reports/FBgn0036593 protein_coding_gene - - - CG13048 - CG13048 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0034294 Muc55B Mucin 55B http://flybase.org/reports/FBgn0034294 protein_coding_gene extracellular matrix structural constituent ; GO:0005201 | inferred from sequence model biological_process ; GO:0008150 | no biological data available extracellular matrix ; GO:0031012 | inferred from sequence model "Muc55B, CG5765" IPR007931:Protein of unknown function DUF725 CG5765 27-Aug-18 DroID_v2018_08 - - "Cele\F14F9.2, Cele\Y57E12B.4, Cele\F33E2.6" - Mmus\Khdc3 "Hsap\KHDC3L, Hsap\CLEC4F, Hsap\PRR21" "viable,fertile" DRSC21440 K -0.158658669 0.25873674 -0.629524309 -0.243706762 -1.566627092 -0.560463786 FBgn0037000 ZnT77C Zinc transporter 77C http://flybase.org/reports/FBgn0037000 protein_coding_gene zinc ion transmembrane transporter activity ; GO:0005385 | inferred by curator from GO:0016323 zinc efflux transmembrane transporter activity ; GO:0022883 | inferred from direct assay response to zinc ion ; GO:0010043 | inferred from biological aspect of ancestor with PANTHER:PTN000169310 zinc II ion transmembrane transport ; GO:0071577 | inferred from mutant phenotype detoxification of zinc ion ; GO:0010312 | inferred from mutant phenotype regulation of sequestering of zinc ion ; GO:0061088 | inferred from biological aspect of ancestor with PANTHER:PTN000169310 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002524 plasma membrane ; GO:0005886 | inferred from direct assay basolateral plasma membrane ; GO:0016323 | inferred from direct assay "anon-WO0118547.435, CG5130, dZnT77C, ZnT77C, cg5130" "IPR002524:Cation efflux protein, IPR027470:Cation efflux protein, cytoplasmic domain" CG5130 27-Aug-18 DroID_v2018_08 "Drer\slc30a10, Drer\slc30a1a, Drer\LOC100002134, Drer\slc30a1b" "Scer\ZRG17, Scer\ZRC1, Scer\COT1" Cele\cdf-1 "Xtro\slc30a10, Xtro\slc30a1" "Mmus\Slc30a10, Mmus\Slc30a1" "Hsap\SLC30A10, Hsap\SLC30A1" "viable,fertile" FBgn0044331 936 936 http://flybase.org/reports/FBgn0044331 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available 936 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0046212 CG15841 - http://flybase.org/reports/FBgn0046212 protein_coding_gene - - - "CG32952-B, CG32952, CG15841, cg15841" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0042635 l(3)S024314b lethal (3) S024314b http://flybase.org/reports/FBgn0042635 gene - - - "l(3)024314, 0243/14, l(3)S024314, l(3)S024314b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0053430 5SrRNA:CR33430 5SrRNA:CR33430 http://flybase.org/reports/FBgn0053430 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33430, 5SrRNA:CR33430" - CR33430 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267664 lncRNA:CR46002 - http://flybase.org/reports/FBgn0267664 non_protein_coding_gene - - - CR46002 - CR46002 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001268 intro introverted http://flybase.org/reports/FBgn0001268 - gene - - - "l(1)Q56, Q56, YT1, R9-13, 23, l(1)20Ac, l(1)19-88, intro" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,viable" head FBgn0041843 E(Sev-CycE)D50 E(Sev-CycE)D50 http://flybase.org/reports/FBgn0041843 gene - - - E(Sev-CycE)D50 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0035620 CG5150 - http://flybase.org/reports/FBgn0035620 protein_coding_gene alkaline phosphatase activity ; GO:0004035 | inferred from sequence or structural similarity with HGNC:439 dephosphorylation ; GO:0016311 | inferred from sequence or structural similarity with HGNC:439 cell surface ; GO:0009986 | inferred from sequence or structural similarity with HGNC:439 CG5150 "IPR001952:Alkaline phosphatase, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha, IPR017850:Alkaline-phosphatase-like, core domain" CG5150 27-Aug-18 DroID_v2018_08 "Drer\alpi.1, Drer\alp3, Drer\alpl, Drer\alpi.2" Scer\PHO8 - "Xtro\alpl, Xtro\alpi.1" "Mmus\Alpi, Mmus\Alpl, Mmus\Alppl2, Mmus\Akp3" "Hsap\ALPL, Hsap\ALPI, Hsap\ALPPL2, Hsap\ALPP" "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0065519 l(2)SH1139 lethal (2) SH1139 http://flybase.org/reports/FBgn0065519 gene - - - "l(2)SH1139, l(2)SH2 1139" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0005053 fs(1)ne6 female sterile (1) no eggs 6 http://flybase.org/reports/FBgn0005053 - gene - - - "ne6, fs(1)ne[6], fs(1)ne6" - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive" "oocyte,dorsal appendage,chorion" FBgn0031972 Wwox WW domain containing oxidoreductase http://flybase.org/reports/FBgn0031972 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN000673029 defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype response to ionizing radiation ; GO:0010212 | inferred from mutant phenotype regulation of reactive oxygen species metabolic process ; GO:2000377 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay "CG7221, DmWWOX, anon-EST:Posey177, Wwox, WWOX" "IPR001202:WW domain, IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain" CG7221 27-Aug-18 DroID_v2018_08 "Drer\flj13639, Drer\rdh14a, Drer\si:dkey-94e7.2, Drer\si:dkey-174n20.1, Drer\si:dkey-23o4.6, Drer\cbr1, Drer\zgc:153441, Drer\cbr1l, Drer\si:ch211-165b10.3, Drer\zgc:64106, Drer\dhrs12, Drer\si:dkey-73n8.3, Drer\dhrs13a.1, Drer\dhrsx, Drer\hsd17b7, Drer\si:ch211-107o10.3, Drer\dhrs13l1, Drer\rdh14b, Drer\rdh12l, Drer\rdh12, Drer\zgc:112332, Drer\wwox, Drer\dhrs13a.3, Drer\dhrs13a.2" "Scer\ENV9, Scer\YNL181W, Scer\ERG27, Scer\YKL107W" "Cele\K10H10.6, Cele\dhs-8, Cele\DC2.5, Cele\sav-1, Cele\F32A5.8, Cele\E04F6.15, Cele\dhs-17, Cele\dhs-7" "Xtro\rdh14, Xtro\dhrs12, Xtro\rdh13, Xtro\rdh11, Xtro\dhrs13, Xtro\dhrsx" "Mmus\Hsd17b7, Mmus\Cbr3, Mmus\Cbr1, Mmus\Dhrsx, Mmus\Rdh11, Mmus\Rdh12, Mmus\Dhrs13, Mmus\Wwox, Mmus\Rdh13, Mmus\Rdh14, Mmus\1700003E16Rik" "Hsap\WWOX, Hsap\CBR3, Hsap\CBR1, Hsap\DHRS13, Hsap\DHRSX, Hsap\RDH13, Hsap\RDH11, Hsap\RDH14, Hsap\OSTC, Hsap\DHRS12, Hsap\HSD17B7, Hsap\RDH12, Hsap\C2orf81" "viable,fertile" DRSC22872 K 0.442505481 1.199127844 -0.486242807 1.059459968 -0.380161871 -1.583997227 FBgn0037668 CG16736 - http://flybase.org/reports/FBgn0037668 protein_coding_gene - - - CG16736 "IPR023395:Mitochondrial carrier domain, IPR018108:Mitochondrial substrate/solute carrier" CG16736 27-Aug-18 DroID_v2018_08 "Drer\si:ch1073-100f3.2, Drer\slc25a10, Drer\slc25a11" Scer\DIC1 Cele\slc-25A10 "Xtro\rangrf, Xtro\slc25a10" "Mmus\Slc25a11, Mmus\Slc25a10" "Hsap\SLC25A10, Hsap\SLC25A11" FBgn0031792 CG13983 - http://flybase.org/reports/FBgn0031792 protein_coding_gene - lateral inhibition ; GO:0046331 | inferred from mutant phenotype - CG13983 - CG13983 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible" "chaeta,supernumerary,trichogen cell" DRSC02315 K 0.003721968 -0.20044766 0.287670762 0.489890641 1.53554137 0.335697266 FBgn0084286 Rst(1b)Cyr Resistance 1b Cyromazine http://flybase.org/reports/FBgn0084286 gene - - - Rst(1b)Cyr - - 27-Aug-18 DroID_v2018_08 - - - - - - "chemical resistant,dominant,partially" FBgn0060670 l(3)S079101 lethal (3) S079101 http://flybase.org/reports/FBgn0060670 gene - - - "0791/01, l(3)S079101" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0262401 mir-285 mir-285 stem loop http://flybase.org/reports/FBgn0262401 miRNA_gene - - - "dme-mir-285, miR-285, mir-285, CR42941, CR33601" - CR42941 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible,lethal" wing FBgn0266694 lncRNA:CR45184 - http://flybase.org/reports/FBgn0266694 non_protein_coding_gene - - - CR45184 - CR45184 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034898 CG18128 - http://flybase.org/reports/FBgn0034898 protein_coding_gene purine-nucleoside phosphorylase activity ; GO:0004731 | inferred from electronic annotation with InterPro:IPR011268 nucleoside metabolic process ; GO:0009116 | inferred from electronic annotation with InterPro:IPR000845 - CG18128 "IPR000845:Nucleoside phosphorylase domain, IPR011268:Purine nucleoside phosphorylase" CG18128 27-Aug-18 DroID_v2018_08 "Drer\pnp5a, Drer\pnp5b, Drer\pnp4b, Drer\pnp4a, Drer\pnp6" Scer\PNP1 Cele\K02D7.1 Xtro\pnp "Mmus\Pnp, Mmus\Pnp2" Hsap\PNP "partially lethal - majority die,visible" mesothoracic tergum FBgn0085564 CG41234 - http://flybase.org/reports/FBgn0085564 protein_coding_gene - - - CG41234 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039677 ppk30 pickpocket 30 http://flybase.org/reports/FBgn0039677 protein_coding_gene sodium channel activity ; GO:0005272 | inferred from sequence or structural similarity with MGI:MGI:101782 sodium ion transport ; GO:0006814 | inferred from sequence or structural similarity with MGI:MGI:101782 regulation of terminal button organization ; GO:2000331 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with MGI:MGI:101782 "CG18110, ppk30" IPR001873:Epithelial sodium channel CG18110 27-Aug-18 DroID_v2018_08 "Drer\asic1c, Drer\asic4a, Drer\asic4b, Drer\asic1a, Drer\asic1b, Drer\asic2" - "Cele\delm-2, Cele\del-5, Cele\acd-2, Cele\acd-4, Cele\acd-5, Cele\acd-1, Cele\flr-1, Cele\delm-1, Cele\del-9" "Xtro\asic5, Xtro\scnn1g, Xtro\scnn1b, Xtro\asic4, Xtro\scnn1a, Xtro\asic1, Xtro\scnn1d" "Mmus\Scnn1g, Mmus\Asic2, Mmus\Asic4, Mmus\Scnn1b, Mmus\Asic1, Mmus\Scnn1a, Mmus\Asic5, Mmus\Asic3" "Hsap\ASIC2, Hsap\ASIC1, Hsap\SCNN1G, Hsap\ASIC3, Hsap\SCNN1B, Hsap\SCNN1A, Hsap\ASIC5, Hsap\SCNN1D, Hsap\ASIC4" "viable,lethal" FBgn0003547 su(Bar) suppressor of Bar http://flybase.org/reports/FBgn0003547 - gene - - - "m(B), M(B), su(B), su(Bar)" - - 27-Aug-18 DroID_v2018_08 - - - - - - ommatidium FBgn0058307 CG40307 - http://flybase.org/reports/FBgn0058307 protein_coding_gene - - - CG40307 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0028199 l(3)S020114 lethal (3) S020114 http://flybase.org/reports/FBgn0028199 gene - - - "0201/14, l(3)S020114" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0038127 CG8476 - http://flybase.org/reports/FBgn0038127 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG8476 IPR001623:DnaJ domain CG8476 27-Aug-18 DroID_v2018_08 "Drer\dnajc16, Drer\dnaja3b, Drer\dnajc4, Drer\dnajc24, Drer\dnaja3a, Drer\dnajc16l" Scer\MDJ1 "Cele\dnj-3, Cele\dnj-4" "Xtro\dnajc16, Xtro\dnajc24, Xtro\dnajc4" "Mmus\Dnajc24, Mmus\Dnaja3, Mmus\Dnajc4, Mmus\Dnajc16" "Hsap\DNAJC24, Hsap\DNAJA3, Hsap\DNAJC16, Hsap\DNAJC4" FBgn0014403 vcg ventral central gaps http://flybase.org/reports/FBgn0014403 - gene - - - vcg - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "longitudinal connective,commissure,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt" FBgn0051687 CG31687 - http://flybase.org/reports/FBgn0051687 protein_coding_gene - regulation of mitotic metaphase/anaphase transition ; GO:0030071 | inferred from electronic annotation with InterPro:IPR007192 regulation of establishment of planar polarity ; GO:0090175 | inferred from mutant phenotype anaphase-promoting complex ; GO:0005680 | inferred from electronic annotation with InterPro:IPR007192 "CG31687, CG31687-PA" "IPR007192:Cdc23, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat, IPR011990:Tetratricopeptide-like helical domain" CG31687 27-Aug-18 DroID_v2018_08 Drer\cdc23 Scer\CDC23 Cele\mat-3 Xtro\cdc23 Mmus\Cdc23 Hsap\CDC23 planar polarity defective "ommatidium,wing hair,supernumerary" FBgn0053512 dpr4 defective proboscis extension response 4 http://flybase.org/reports/FBgn0053512 protein_coding_gene molecular_function ; GO:0003674 | no biological data available synapse organization ; GO:0050808 | inferred from expression pattern sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with dpr1 cellular_component ; GO:0005575 | no biological data available "CG12593, Dpr-4, CT34497, CG14707, CG33512, dpr4, Dpr4" "IPR013106:Immunoglobulin V-set domain, IPR003598:Immunoglobulin subtype 2, IPR013783:Immunoglobulin-like fold, IPR007110:Immunoglobulin-like domain, IPR003599:Immunoglobulin subtype" CG33512 27-Aug-18 DroID_v2018_08 "Drer\LOC108191960, Drer\LOC100333196, Drer\zgc:112965, Drer\LOC101885444, Drer\si:dkey-65b12.12, Drer\LOC101885725, Drer\si:ch211-163c2.2" - Cele\zig-8 "Xtro\obsl1, Xtro\nfasc" "Mmus\Amica1, Mmus\Gm1123" Hsap\JAML viable FBgn0001238 hv heavy vein http://flybase.org/reports/FBgn0001238 - gene - - - hv - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing vein,crossvein,wing,eye,posterior scutellar bristle" FBgn0065777 l(2)SH0449 lethal (2) SH0449 http://flybase.org/reports/FBgn0065777 gene - - - "l(2)SH0449, l(2)SH2 0449" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0017558 Pdk Pyruvate dehydrogenase kinase http://flybase.org/reports/FBgn0017558 FBgn0062465 protein_coding_gene protein kinase activity ; GO:0004672 | inferred from sequence or structural similarity with UniProtKB:Q15118 pyruvate dehydrogenase (acetyl-transferring) kinase activity ; GO:0004740 | inferred from sequence or structural similarity with UniProtKB:Q15118 pyruvate metabolic process ; GO:0006090 | inferred from sequence or structural similarity with UniProtKB:Q15118 mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:Q15118 "CG8808, DmPdk, DmPDK, BcDNA:LD09837, Pdk, pdk, PDK" "IPR003594:Histidine kinase-like ATPase, C-terminal domain, IPR005467:Histidine kinase domain, IPR018955:Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal" CG8808 27-Aug-18 DroID_v2018_08 "Drer\pdk4, Drer\bckdk, Drer\pdk2a, Drer\pdk1, Drer\pdk3a, Drer\pdk2b, Drer\pdk3b" "Scer\PKP1, Scer\PKP2" Cele\pdhk-2 "Xtro\pdk4, Xtro\pdk1, Xtro\bckdk, Xtro\pdk3" "Mmus\Bckdk, Mmus\Pdk4, Mmus\Pdk1, Mmus\Pdk3, Mmus\Pdk2" "Hsap\PDK4, Hsap\PDK2, Hsap\BCKDK, Hsap\PDK3, Hsap\PDK1" " adult stage | female , embryonic stage | 0-20 hr , pupal stage , adult stage | male , larval stage | third instar , embryonic stage "

ubiquitous "viable,fertile" FBgn0065721 l(2)SH0569 lethal (2) SH0569 http://flybase.org/reports/FBgn0065721 gene - - - "l(2)SH0569, l(2)SH2 0569" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0005448 l(1)v223 lethal (1) v223 http://flybase.org/reports/FBgn0005448 - gene - - - "l(1)223, l(1)v223" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039131 CG12268 - http://flybase.org/reports/FBgn0039131 protein_coding_gene fatty-acyl-CoA reductase (alcohol-forming) activity ; GO:0080019 | inferred from sequence or structural similarity with HGNC:26222 - - CG12268 "IPR013120:Male sterility, NAD-binding, IPR016040:NAD(P)-binding domain, IPR026055:Fatty acyl-CoA reductase, IPR033640:Fatty acyl-CoA reductase, C-terminal" CG12268 27-Aug-18 DroID_v2018_08 "Drer\far1, Drer\si:dkey-97m3.1" Scer\LYS2 Cele\fard-1 Xtro\far1 "Mmus\Far2, Mmus\Far1" "Hsap\FAR1, Hsap\FAR2" "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0263771 CR43688 - http://flybase.org/reports/FBgn0263771 pseudogene_attribute - - - CR43688 - CR43688 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0083167 Neb-cGP Neb-cGP http://flybase.org/reports/FBgn0083167 protein_coding_gene hormone activity ; GO:0005179 | traceable author statement regulation of growth ; GO:0040008 | traceable author statement extracellular space ; GO:0005615 | traceable author statement mitochondrial proton-transporting ATP synthase complex ; GO:0005753 | inferred from biological aspect of ancestor with PANTHER:PTN002145699 "pncr006:X, CG15304, BcDNA:RH45340, BcDNA:RE31692, Neb-cGP" IPR009125:DAPIT CG15304 27-Aug-18 DroID_v2018_08 Drer\si:dkeyp-80c12.10 - - - Mmus\Usmg5 Hsap\USMG5 "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0028387 chm chameau http://flybase.org/reports/FBgn0028387 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR002515 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR002515 transcription factor binding ; GO:0008134 | inferred from physical interaction with Jra inferred from physical interaction with kay histone acetyltransferase activity ; GO:0004402 | traceable author statement H3 histone acetyltransferase activity ; GO:0010484 | inferred from direct assay H4 histone acetyltransferase activity ; GO:0010485 | inferred from direct assay transcription coactivator activity ; GO:0003713 | inferred from direct assay" "positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay chaeta development ; GO:0022416 | inferred from mutant phenotype histone acetylation ; GO:0016573 | inferred from mutant phenotype histone H3 acetylation ; GO:0043966 | inferred from direct assay neuron development ; GO:0048666 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap sensory organ precursor cell fate determination ; GO:0016360 | inferred from mutant phenotype imaginal disc fusion, thorax closure ; GO:0046529 | inferred from mutant phenotype negative regulation of cell fate specification ; GO:0009996 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype gene silencing ; GO:0016458 | inferred from genetic interaction with Pc gene silencing ; GO:0016458 | traceable author statement positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from direct assay negative regulation of transcription, DNA-templated ; GO:0045892 | traceable author statement dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay "chm, HAT1, dmHAG404, CG5229, HAT, HBO1, Chm" "IPR002515:Zinc finger, C2HC-type, IPR002717:Histone acetyltransferase domain, MYST-type, IPR016181:Acyl-CoA N-acyltransferase" CG5229 27-Aug-18 DroID_v2018_08 "Drer\kat5b, Drer\kat5a, Drer\kat8, Drer\kat7a, Drer\kat7b, Drer\kat6a, Drer\kat6b" "Scer\SAS3, Scer\SAS2, Scer\ESA1" "Cele\mys-2, Cele\mys-1, Cele\mys-4, Cele\lsy-12" "Xtro\kat8, Xtro\trim69.1, Xtro\kat7, Xtro\xnf7, Xtro\kat5" "Mmus\Kat8, Mmus\Kat7, Mmus\Kat6a, Mmus\Kat5, Mmus\Kat6b" "Hsap\KAT8, Hsap\KAT7, Hsap\KAT6A, Hsap\KAT6B, Hsap\KAT5" "suppressor of variegation,dominant,lethal - all die before end of pupal stage,recessive,some die during pupal stage,wild-type,viable" adult thorax DRSC24941 K -0.371367026 -0.347656926 0.370704248 0.530648663 -1.502221657 0.153279396 FBgn0039840 pHCl-2 pH-sensitive chloride channel 2 http://flybase.org/reports/FBgn0039840 protein_coding_gene extracellular ligand-gated ion channel activity ; GO:0005230 | inferred from electronic annotation with InterPro:IPR006202 chloride channel activity ; GO:0005254 | inferred from direct assay pH-gated chloride channel activity ; GO:0061797 | inferred from direct assay chloride transport ; GO:0006821 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from direct assay "CG11340, CT5896, Lcch-100C, lincRNA.914, pHCl-2" "IPR006028:Gamma-aminobutyric acid A receptor/Glycine receptor alpha, IPR006029:Neurotransmitter-gated ion-channel transmembrane domain, IPR006201:Neurotransmitter-gated ion-channel, IPR006202:Neurotransmitter-gated ion-channel ligand-binding domain, IPR018000:Neurotransmitter-gated ion-channel, conserved site" CG11340 27-Aug-18 DroID_v2018_08 "Drer\glra4a, Drer\glra3, Drer\glra1, Drer\glrbb, Drer\glra4b, Drer\glra2, Drer\glrba" - "Cele\glc-1, Cele\glc-3, Cele\lgc-54, Cele\lgc-53, Cele\mod-1, Cele\acc-4, Cele\lgc-47, Cele\glc-2, Cele\lgc-55, Cele\lgc-50, Cele\acc-2, Cele\lgc-38, Cele\lgc-46, Cele\pbo-5, Cele\avr-14, Cele\lgc-52, Cele\ggr-3, Cele\avr-15, Cele\lgc-51, Cele\glc-4, Cele\acc-3, Cele\acc-1, Cele\lgc-49, Cele\lgc-48" "Xtro\glra1, Xtro\glra2, Xtro\glra3, Xtro\glrb" "Mmus\Glra4, Mmus\Glra1, Mmus\Glrb, Mmus\Glra3, Mmus\Glra2, Mmus\Gabrp" "Hsap\GLRA2, Hsap\GLRA4, Hsap\GLRB, Hsap\GLRA3, Hsap\GABRP, Hsap\GLRA1" "viable,fertile" DRSC14306 EK 1.016128472 0.681938305 1.863558529 1.254861527 0.556120495 1.730679265 FBgn0036220 CG5897 - http://flybase.org/reports/FBgn0036220 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG5897 IPR002557:Chitin binding domain CG5897 27-Aug-18 DroID_v2018_08 Drer\thbd - "Cele\R02F2.4, Cele\cpg-2, Cele\cpg-1, Cele\C39D10.7" - - Hsap\MATN2 "partially lethal - majority die,some die during pupal stage" FBgn0051976 ovm oven mitt http://flybase.org/reports/FBgn0051976 protein_coding_gene molecular_function ; GO:0003674 | no biological data available positive regulation of dendrite morphogenesis ; GO:0050775 | inferred from mutant phenotype detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG31976, CG11623, ovm" IPR010512:Protein of unknown function DUF1091 CG31976 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible" trichogen cell FBgn0005124 l(1)J1743 lethal (1) J1743 http://flybase.org/reports/FBgn0005124 - gene - - - l(1)J1743 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,heat sensitive" FBgn0069132 mei(2)yh149 mei(2)yh149 http://flybase.org/reports/FBgn0069132 gene - male meiosis chromosome segregation ; GO:0007060 | inferred from mutant phenotype - mei(2)yh149 - - 27-Aug-18 DroID_v2018_08 - - - - - - "meiotic cell cycle defective,male,recessive,female fertile" FBgn0003670 tbl tasteblind http://flybase.org/reports/FBgn0003670 - gene - - - tbl - - 27-Aug-18 DroID_v2018_08 - - - - - - chemosensitive behavior defective FBgn0259627 B2033 - http://flybase.org/reports/FBgn0259627 gene - - - B2033 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible wing FBgn0060388 l(3)S134012a lethal (3) S134012a http://flybase.org/reports/FBgn0060388 gene - - - "1340/12, l(3)S134012a" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0039073 CG4408 - http://flybase.org/reports/FBgn0039073 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000834 metallocarboxypeptidase activity ; GO:0004181 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000834, InterPro:IPR003146" extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 "BEST:GH09055, CG4408" "IPR000834:Peptidase M14, carboxypeptidase A, IPR009020:Protease propeptides/proteinase inhibitor I9, IPR034223:Insect gut carboxypeptidase-like, carboxypeptidase domain, IPR003146:Carboxypeptidase, activation peptide" CG4408 27-Aug-18 DroID_v2018_08 "Drer\cpo, Drer\cpa5, Drer\cpa4, Drer\cpb1, Drer\cpa6, Drer\cpa1, Drer\cpa2, Drer\cpb2" Scer\ECM14 "Cele\W01A8.6, Cele\T06A4.1, Cele\ZC434.9, Cele\suro-1, Cele\Y18H1A.9, Cele\Y47G6A.19, Cele\Y59C2A.1, Cele\F02D8.4, Cele\T06A4.3" "Xtro\cpa3, Xtro\cpo, Xtro\LOC100490370, Xtro\cpa1, Xtro\cpb1, Xtro\cpb2" "Mmus\Cpa4, Mmus\Cpa5, Mmus\Cpb2, Mmus\Cpb1, Mmus\Cpa6, Mmus\Cpa2, Mmus\Cpm, Mmus\Cpa3, Mmus\Cpa1" "Hsap\CPA1, Hsap\CPO, Hsap\CPA3, Hsap\CPA6, Hsap\CPA2, Hsap\CPA4, Hsap\CPA5, Hsap\CPB1, Hsap\CPM, Hsap\CPB2" viable FBgn0000317 ck crinkled http://flybase.org/reports/FBgn0000317 "FBgn0015260, FBgn0015868, FBgn0020027, FBgn0044341" protein_coding_gene "myosin light chain binding ; GO:0032027 | inferred from physical interaction with Mlc-c motor activity ; GO:0003774 | inferred from sequence or structural similarity with NCBI_gi:613788 actin-dependent ATPase activity ; GO:0030898 | inferred from direct assay cadherin binding ; GO:0045296 | inferred from physical interaction with Cad99C ATP binding ; GO:0005524 | inferred from direct assay actin binding ; GO:0003779 | inferred from sequence or structural similarity with NCBI_gi:613788 ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity" antennal morphogenesis ; GO:0048800 | inferred from mutant phenotype chitin-based larval cuticle pattern formation ; GO:0035293 | inferred from genetic interaction with wg actin filament-based movement ; GO:0030048 | inferred from direct assay actin filament organization ; GO:0007015 | inferred from mutant phenotype imaginal disc-derived wing hair organization ; GO:0035317 | inferred from genetic interaction with dsh inferred from genetic interaction with fz chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype imaginal disc-derived wing hair organization ; GO:0035317 | inferred from genetic interaction with spen antennal development ; GO:0007469 | inferred from mutant phenotype sensory organ development ; GO:0007423 | inferred from mutant phenotype imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from genetic interaction with spen sensory perception of sound ; GO:0007605 | inferred from mutant phenotype follicle cell microvillus organization ; GO:0032529 | inferred from mutant phenotype microvillus ; GO:0005902 | inferred from direct assay unconventional myosin complex ; GO:0016461 | inferred from sequence or structural similarity with NCBI_gi:613788 micropyle ; GO:0070825 | inferred from direct assay myosin VII complex ; GO:0031477 | inferred from physical interaction with Mlc-c myosin complex ; GO:0016459 | inferred from sequence or structural similarity apical cortex ; GO:0045179 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay female germline ring canal outer rim ; GO:0035182 | inferred from direct assay basal cortex ; GO:0045180 | inferred from direct assay unconventional myosin complex ; GO:0016461 | inferred from sequence or structural similarity cell cortex ; GO:0005938 | inferred from direct assay filamentous actin ; GO:0031941 | colocalizes_with inferred from direct assay "CG7595, ck, myoVIIA, DmVIIa, DMyoVIIa, Dm 35B, DmVIIA, anon-35Bb, BG:DS00929.11, l(2)br27, l(2)35Ca, Mhc35BC, 53D10S, Dro35B, l35Ca, br27, D, D2, stc, l(2)07130, l(1)35Ca, ESTS:53D10S, stch, ck/MyoVIIA, MyoVIIA, DM7a, Myo7A, Myo7B" "IPR000048:IQ motif, EF-hand binding site, IPR000299:FERM domain, IPR000857:MyTH4 domain, IPR001452:SH3 domain, IPR001609:Myosin head, motor domain, IPR014352:FERM/acyl-CoA-binding protein, 3-helical bundle, IPR019748:FERM central domain, IPR019749:Band 4.1 domain, IPR029071:Ubiquitin-related domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR011993:PH domain-like" CG7595 27-Aug-18 DroID_v2018_08 "Drer\myo10l3, Drer\myo7bb, Drer\myo9ab, Drer\LOC556989, Drer\myo15b, Drer\myo7aa, Drer\myo9aa, Drer\myo15aa, Drer\si:ch73-194h10.2, Drer\myo10, Drer\myo10l1, Drer\myo7ab, Drer\myo9b, Drer\myo3b, Drer\myo15ab" "Scer\MYO2, Scer\MYO1" Cele\hum-6 "Xtro\myo10.2, Xtro\myo3b, Xtro\myo10, Xtro\myo9a, Xtro\myo3a, Xtro\myo7a" "Mmus\Myo10, Mmus\Myo15, Mmus\Myo7b, Mmus\Myo9a, Mmus\Myo9b, Mmus\Myo3a, Mmus\Myo7a, Mmus\Myo3b" "Hsap\MYO10, Hsap\MYO15A, Hsap\MYO3B, Hsap\MYO9B, Hsap\MYO7B, Hsap\MYO3A, Hsap\MYO7A, Hsap\MYO9A" "viable,fertile,auditory perception defective,visible,recessive,partially lethal - majority die,lethal,lethal - all die before end of larval stage,some die during larval stage,sterile,lethal - all die before end of embryonic stage,some die during embryonic stage" "Johnston's organ & scolopidium,Johnston's organ & dendritic cap cell,wing hair,supernumerary,dorsal fine hair,ocellar bristle,arista,ectopic,macrochaeta,microchaeta,trichogen cell,wing,male genitalia" FBgn0051644 CG31644 - http://flybase.org/reports/FBgn0051644 protein_coding_gene cytochrome-c oxidase activity ; GO:0004129 | inferred from electronic annotation with InterPro:IPR004204 molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT20031, CG31644" IPR004204:Cytochrome c oxidase subunit 6C CG31644 27-Aug-18 DroID_v2018_08 Drer\cox6c - "Cele\Y111B2A.2, Cele\B0035.18, Cele\F29C4.2" Xtro\LOC100489195 Mmus\Cox6c Hsap\COX6C viable FBgn0003182 Q Queer wing http://flybase.org/reports/FBgn0003182 - gene - - - Q - - 27-Aug-18 DroID_v2018_08 - - - - - - "wing,abdominal tergite marginal bristle" FBgn0034918 Pym Partner of Y14 and Mago http://flybase.org/reports/FBgn0034918 protein_coding_gene exon-exon junction complex binding ; GO:1990448 | inferred from physical interaction with mago inferred from physical interaction with tsu ribosomal small subunit binding ; GO:0043024 | NOT inferred from direct assay inferred from physical interaction with RpL32 inferred from physical interaction with RpS6 RNA binding ; GO:0003723 | inferred from direct assay eukaryotic initiation factor 4G binding ; GO:0031370 | NOT inferred from physical interaction with eIF4G1 eukaryotic initiation factor 4E binding ; GO:0008190 | NOT inferred from physical interaction with eIF4E1 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P49028 inferred from physical interaction with UniProtKB:Q9V535 "nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ; GO:0000184 | inferred from sequence or structural similarity with UniProtKB:Q9BRP8 exon-exon junction complex disassembly ; GO:1903259 | inferred from mutant phenotype cap-dependent translational initiation ; GO:0002191 | NOT inferred from physical interaction with Cbp20 inferred from physical interaction with pAbp" exon-exon junction complex ; GO:0035145 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "Pym, UD3, CG10330, CG30176, BEST:HL05757, wibg, PYM, pym, Wibg" IPR015362:WIBG family CG30176 27-Aug-18 DroID_v2018_08 Drer\pym1 - Cele\T20G5.9 Xtro\pym1 Mmus\Pym1 Hsap\PYM1 "female fertile,female semi-sterile,grandchildless,viable,lethal,recessive" ovary FBgn0284248 Cyt-c-p Cytochrome c proximal http://flybase.org/reports/FBgn0284248 protein_coding_gene "heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR002327, InterPro:IPR009056 electron carrier activity ; GO:0009055 | inferred from direct assay" oxidative phosphorylation ; GO:0006119 | inferred from sequence or structural similarity with SGD:S000003809 mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with SGD:S000003809 cytosol ; GO:0005829 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay "Cyt-c-p, l(2)k13905, CG17903, cytC-p, cyt-c-p, cytochrome c, Cyt-c2, Cytc, cyt-c2, cyt.c, DC4, DMc01, pDMc01, CytC-2, Cytc-p, dc4, cyt c-p, Cyct-c-p, cyt c, Cyt c, CytC, Cyt C, dCyt.C-p, CYC" "IPR002327:Cytochrome c, class IA/ IB, IPR009056:Cytochrome c-like domain" CG17903 27-Aug-18 DroID_v2018_08 Drer\cycsb "Scer\CYC1, Scer\CYC7" "Cele\cyc-2.2, Cele\cyc-2.1" "Xtro\cycs, Xtro\cyct" "Mmus\Cycs, Mmus\Cyct" Hsap\CYCS " adult stage , larval stage--adult stage " " adult thorax

, adult head

, adult abdomen

" "lethal,lethal - all die before end of first instar larval stage,some die during first instar larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,visible" "trichogen cell,mesothoracic tergum" FBgn0086662 snoRNA:Psi28S-3186 snoRNA:Psi28S-3186 http://flybase.org/reports/FBgn0086662 snoRNA_gene - - - "snoRNA:165, psi28s-3186, Dm-165, snoR165, CR33709, Psi 28S-3186(SnoR165), snoRNA:Psi28S-3186, psi-28S-3168, pug28S-3186" - CR33709 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0087012 5-HT2A 5-hydroxytryptamine (serotonin) receptor 2A http://flybase.org/reports/FBgn0087012 protein_coding_gene G-protein coupled amine receptor activity ; GO:0008227 | inferred from sequence or structural similarity G-protein coupled serotonin receptor activity ; GO:0004993 | inferred from direct assay neurotransmitter receptor activity ; GO:0030594 | inferred from biological aspect of ancestor with PANTHER:PTN000664111 G-protein coupled serotonin receptor activity ; GO:0004993 | traceable author statement Gq/11-coupled serotonin receptor activity ; GO:0001587 | non-traceable author statement G-protein coupled serotonin receptor activity ; GO:0004993 | inferred from sequence or structural similarity serotonin receptor signaling pathway ; GO:0007210 | traceable author statement serotonin receptor signaling pathway ; GO:0007210 | inferred from sequence or structural similarity germ-band extension ; GO:0007377 | inferred from mutant phenotype serotonin receptor signaling pathway ; GO:0007210 | inferred from direct assay inferred from mutant phenotype positive regulation of feeding behavior ; GO:2000253 | inferred from mutant phenotype "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR017452 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity" "l(3)82CDb, 5-HT[[2Dro]], 5-HT2Dro, Dm5HT2, 5HT2-Dro, 5HT[[2Dro]], 5-ht2Dro, 5HT2Dro, 5-HT[[2]], 5HT-dro[[1]], CG1056, 5HT-R82A, d5-HT2, 5-HT[[2]]Dro, 5-HT2, 5-HT[2]Dro, 5HT2, 5-HT2A, d5-HT2A, 5HT2a" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG1056 27-Aug-18 DroID_v2018_08 "Drer\gpr27, Drer\htr2b, Drer\htr2cl1, Drer\gpr85, Drer\gpr173, Drer\htr2aa, Drer\htr2ab, Drer\htr2cl2" - "Cele\ser-1, Cele\ser-2" "Xtro\htr2c, Xtro\gpr85, Xtro\gpr173" "Mmus\Gpr173, Mmus\Htr2b, Mmus\Gpr27, Mmus\Htr2a, Mmus\Gpr85, Mmus\Htr2c" "Hsap\GPR173, Hsap\GPR85, Hsap\HTR2A, Hsap\HTR2C, Hsap\HTR2B, Hsap\GPR27" " embryonic stage | stage 5 , embryonic stage | stage >=13 " " organism | even pair rule

, central nervous system | restricted

" FBgn0000056 Adhr Adh-related http://flybase.org/reports/FBgn0000056 "FBgn0052954, FBtr0080648, FBpp0080216, FBtr0080649, FBpp0080217, FBtr0080650, FBpp0080218, FBtr0080651, FBpp0080219, FBtr0080652, FBpp0080220, FBtr0080653, FBpp0080221, FBtr0080654, FBpp0080222, FBtr0080655, FBpp0080223" protein_coding_gene alcohol dehydrogenase (NAD) activity ; GO:0004022 | inferred from electronic annotation with InterPro:IPR002424 NAD binding ; GO:0051287 | NOT traceable author statement alcohol dehydrogenase (NAD) activity ; GO:0004022 | NOT traceable author statement oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR002424 cellular_component ; GO:0005575 | no biological data available "Adh-dup, ADHR, BG:DS01486.9, ADH[r], Adh[r], 3'ORF, CG32954, CG3484, Adhr" "IPR002424:Alcohol dehydrogenase, insect-type, IPR002427:Alcohol dehydrogenase-related, IPR016040:NAD(P)-binding domain, IPR020904:Short-chain dehydrogenase/reductase, conserved site, IPR002347:Short-chain dehydrogenase/reductase SDR" CG3484 27-Aug-18 DroID_v2018_08 "Drer\hsd17b2, Drer\zgc:56585, Drer\hsd11b2, Drer\hpgd" Scer\SPS19 "Cele\T01G6.10, Cele\C01G12.5, Cele\dhs-16, Cele\W03F9.9, Cele\T01G6.1, Cele\dhs-2, Cele\drd-5, Cele\dhs-20, Cele\C06B8.3" Xtro\hpgd "Mmus\Hsd17b2, Mmus\Hpgd, Mmus\Hsd11b2, Mmus\Bdh1" "Hsap\HSD11B2, Hsap\HPGD, Hsap\HSD17B2, Hsap\BDH1" FBgn0041180 Tep4 Thioester-containing protein 4 http://flybase.org/reports/FBgn0041180 protein_coding_gene "endopeptidase inhibitor activity ; GO:0004866 | inferred from electronic annotation with InterPro:IPR001599, InterPro:IPR002890" multicellular organism reproduction ; GO:0032504 | inferred from expression pattern response to fungus ; GO:0009620 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from electronic annotation with InterPro:IPR011626 extracellular space ; GO:0005615 | inferred from sequence model "Tep4, TepIV, CG10363, CT29102, dTEPIV, TEP IV, TEP4mel, tep4, TEP4, tepIV, TEPIV, Tep IV" "IPR002890:Alpha-2-macroglobulin, N-terminal, IPR008930:Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid, IPR009048:Alpha-macroglobulin, receptor-binding, IPR011625:Alpha-2-macroglobulin, N-terminal 2, IPR011626:Alpha-macroglobulin complement component, IPR014756:Immunoglobulin E-set, IPR019742:Alpha-2-macroglobulin, conserved site, IPR013783:Immunoglobulin-like fold, IPR019565:Alpha-2-macroglobulin, thiol-ester bond-forming, IPR001599:Alpha-2-macroglobulin" CG10363 27-Aug-18 DroID_v2018_08 "Drer\a2ml, Drer\cd109, Drer\si:dkey-46g23.2, Drer\c3b.2, Drer\c3b.1, Drer\cpamd8, Drer\si:dkey-8k3.2, Drer\c3a.6, Drer\c3a.2, Drer\zgc:165518, Drer\c3a.4, Drer\c5, Drer\si:dkey-52d15.2, Drer\c4, Drer\c3a.3, Drer\c3a.1" - Cele\tep-1 "Xtro\a2m, Xtro\c5, Xtro\c3, Xtro\c4a, Xtro\pzp, Xtro\a2ml1" "Mmus\Hc, Mmus\Mug1, Mmus\C3, Mmus\C4b, Mmus\Mug2, Mmus\Cd109" "Hsap\CD109, Hsap\C4B_2, Hsap\C4B, Hsap\C5, Hsap\CPAMD8, Hsap\C4A, Hsap\C3, Hsap\PZP, Hsap\A2ML1" viable FBgn0058114 CG40114 - http://flybase.org/reports/FBgn0058114 protein_coding_gene - - - CG40114 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032620 CG12288 - http://flybase.org/reports/FBgn0032620 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity - microtubule associated complex ; GO:0005875 | inferred from direct assay "cg12288, CG12288" "IPR000504:RNA recognition motif domain, IPR034220:RBM34, RNA recognition motif 1" CG12288 27-Aug-18 DroID_v2018_08 "Drer\hnrnpaba, Drer\srsf10a, Drer\hnrnpd, Drer\trnau1apa, Drer\rbm34, Drer\trnau1apb, Drer\raly, Drer\zcrb1, Drer\hnrnpabb, Drer\dazl, Drer\hnrnpa1b, Drer\hnrnpc, Drer\wu:fq32h04, Drer\ncoa5, Drer\eif4h, Drer\eif4ba, Drer\cirbpa, Drer\hnrnpa3, Drer\zgc:55733" "Scer\NAM8, Scer\NGR1, Scer\MUD1, Scer\NOP12, Scer\NOP6, Scer\NAB6, Scer\CWC2, Scer\MRN1" "Cele\F11A10.7, Cele\EEED8.4, Cele\T08B6.5" "Xtro\hnrnpdl, Xtro\trnau1ap, Xtro\hnrnpc, Xtro\ralyl, Xtro\eif4h, Xtro\hnrnpd, Xtro\cirbp, Xtro\hnrnpa2b1, Xtro\raly, Xtro\hnrnpa3, Xtro\hnrnpab, Xtro\hnrnpa1, Xtro\rbm34, Xtro\eif4b, Xtro\dazl" "Mmus\Tra2b, Mmus\Hnrnpc, Mmus\Trnau1ap, Mmus\Rbm34, Mmus\Eif4h, Mmus\Srsf12, Mmus\Hnrnpab, Mmus\Boll, Mmus\Hnrnpa3, Mmus\Eif4b, Mmus\Gm21379, Mmus\Rbm31y, Mmus\Cirbp, Mmus\Hnrnpa2b1, Mmus\Zcrb1, Mmus\Slirp, Mmus\Hnrnpa1, Mmus\Hnrnpd, Mmus\Srsf10, Mmus\Raly, Mmus\Dazl" "Hsap\BOLL, Hsap\SRSF10, Hsap\CIRBP, Hsap\RALYL, Hsap\DAZL, Hsap\HNRNPAB, Hsap\DAZ1, Hsap\RBM34, Hsap\EIF4H, Hsap\HNRNPA2B1, Hsap\HNRNPA3, Hsap\HNRNPCL1, Hsap\HNRNPA1, Hsap\HNRNPD, Hsap\TRNAU1AP, Hsap\SLIRP, Hsap\DAZ2, Hsap\RALY, Hsap\EIF4B, Hsap\HNRNPA1L2, Hsap\DAZ4, Hsap\HNRNPC, Hsap\RBM3, Hsap\DAZ3" FBgn0002831 ms(2)E10 male sterile (2) E10 http://flybase.org/reports/FBgn0002831 - gene - - - "ms2.10, ms(2)2.10, ms(2)E10" - - 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,recessive" FBgn0051347 CG31347 - http://flybase.org/reports/FBgn0051347 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG31347 - CG31347 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0265343 asRNA:CR44297 - http://flybase.org/reports/FBgn0265343 non_protein_coding_gene - - - CR44297 - CR44297 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264789 asRNA:CR44019 - http://flybase.org/reports/FBgn0264789 non_protein_coding_gene - - - CR44019 - CR44019 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263846 CG43707 - http://flybase.org/reports/FBgn0263846 protein_coding_gene - - - "CG43707, CG31772, CG31959, CG10020" "IPR001849:Pleckstrin homology domain, IPR011993:PH domain-like, IPR001478:PDZ domain" CG43707 27-Aug-18 DroID_v2018_08 "Drer\pdzph1, Drer\rhpn2, Drer\ppp1r9a, Drer\cnksr1, Drer\ppp1r9ba, Drer\rhpn1" Scer\BOI1 Cele\nab-1 - "Mmus\Pdzph1, Mmus\Rhpn2, Mmus\Ppp1r9a, Mmus\Ipcef1, Mmus\Plekha5, Mmus\Rhpn1, Mmus\Cnksr1, Mmus\Ppp1r9b" "Hsap\PPP1R9B, Hsap\PLEKHA5, Hsap\PPP1R9A, Hsap\CNKSR1, Hsap\RHPN1, Hsap\RHPN2" DRSC22912 K 0.241260386 0.144499459 -0.050174664 1.316653047 1.547089255 0.20151277 FBgn0036196 CG11658 - http://flybase.org/reports/FBgn0036196 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model "anon-WO0118547.413, CG11658, FBXO12" IPR001810:F-box domain CG11658 27-Aug-18 DroID_v2018_08 "Drer\fbxo25, Drer\fbxo32, Drer\lypla2" - "Cele\mfb-1, Cele\ath-1" "Xtro\lypla1, Xtro\lypla2, Xtro\fbxo32, Xtro\fbxo25" "Mmus\Lypla2, Mmus\Fbxo25, Mmus\Fbxo32, Mmus\Lypla1" "Hsap\FBXO25, Hsap\LYPLA1, Hsap\FBXO32, Hsap\LYPLA2, Hsap\FBXO7" "viable,fertile" FBgn0024368 CG18091 - http://flybase.org/reports/FBgn0024368 FBgn0029572 protein_coding_gene - - - "EG:190E7.1, CG18091" - - 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0005213 l(3)ET4 lethal Elaine Tasaka 4 http://flybase.org/reports/FBgn0005213 - gene - - - l(3)ET4 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,cold sensitive,heat sensitive" FBgn0050379 CG30379 - http://flybase.org/reports/FBgn0050379 protein_coding_gene - - - CG30379 IPR006214:Bax inhibitor 1-related CG30379 27-Aug-18 DroID_v2018_08 "Drer\LOC566927, Drer\tmbim1, Drer\grinaa, Drer\tmbim4, Drer\grinab, Drer\si:ch211-284o19.8, Drer\faim2a, Drer\faim2b, Drer\zgc:110410" Scer\BXI1 "Cele\xbx-6, Cele\Y42H9AR.2, Cele\tmbi-4, Cele\tag-120" "Xtro\tmbim1, Xtro\faim2, Xtro\tmbim4" "Mmus\Grina, Mmus\Tmbim4, Mmus\Tmbim7, Mmus\Tmbim1, Mmus\Faim2" "Hsap\FAIM2, Hsap\TMBIM1, Hsap\GRINA, Hsap\TMBIM4" viable FBgn0041760 efe efendi http://flybase.org/reports/FBgn0041760 gene - - - efe - - 27-Aug-18 DroID_v2018_08 - - - - - - "melanotic mass phenotype,recessive,lethal - all die before end of pupal stage,partially,some die during pupal stage,chemical resistant,dominant" "polytene chromosome,melanotic mass,embryonic/larval brain,salivary gland" FBgn0016799 l(1)44 lethal (1) 44 http://flybase.org/reports/FBgn0016799 - gene - - - l(1)44 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,heat sensitive" FBgn0024680 l(1)LefEM26 lethal (1) LefEM26 http://flybase.org/reports/FBgn0024680 - gene - - - "EM26, l(1)LefEM26" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0043457 CG5180 - http://flybase.org/reports/FBgn0043457 protein_coding_gene - - - "LD05530, BEST:LD05530, CG5180" IPR006578:MADF domain CG5180 27-Aug-18 DroID_v2018_08 - - - - - - "visible,viable" "dorsocentral bristle,scutellar bristle,trichogen cell,ectopic,thecogen cell" FBgn0062573 Mod(var)E1275 Mod(var)E1275 http://flybase.org/reports/FBgn0062573 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "E1275, Mod(var)E1275" - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,enhancer of variegation,non-enhancer of variegation,non-suppressor of variegation" FBgn0032117 FucTB FucTB http://flybase.org/reports/FBgn0032117 protein_coding_gene alpha-(1->3)-fucosyltransferase activity ; GO:0046920 | inferred from biological aspect of ancestor with PANTHER:PTN000231531 "protein glycosylation ; GO:0006486 | inferred from electronic annotation with InterPro:IPR001503, InterPro:IPR017176" Golgi membrane ; GO:0000139 | inferred from biological aspect of ancestor with PANTHER:PTN000231531 "CT14430, CG4435, FucTB" "IPR001503:Glycosyl transferase family 10, IPR017176:Alpha-(1, 3)-fucosyltransferase, metazoan, IPR031481:Fucosyltransferase, N-terminal" CG4435 27-Aug-18 DroID_v2018_08 "Drer\ft1, Drer\fut9b, Drer\fut10, Drer\zgc:103510, Drer\zgc:136963, Drer\zgc:112433, Drer\si:ch1073-440p11.2, Drer\zgc:173737, Drer\ft2, Drer\fut9d, Drer\zgc:165582, Drer\zgc:165519, Drer\fut9a, Drer\fut11, Drer\fut7" - Cele\fut-1 "Xtro\fut3, Xtro\fut4, Xtro\fut11, Xtro\fut6, Xtro\fut10, Xtro\fut9" "Mmus\Fut7, Mmus\Fut11, Mmus\Fut10, Mmus\Fut9, Mmus\Fut4" "Hsap\FUT3, Hsap\FUT10, Hsap\FUT9, Hsap\FUT4, Hsap\FUT7, Hsap\FUT11, Hsap\FUT6, Hsap\FUT5" viable FBgn0025150 ms(2)A6 ms(2)A6 http://flybase.org/reports/FBgn0025150 - gene - - - ms(2)A6 - - 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,recessive" FBgn0264509 asRNA:CR43908 - http://flybase.org/reports/FBgn0264509 non_protein_coding_gene - - - CR43908 - CR43908 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266315 lncRNA:CR44980 - http://flybase.org/reports/FBgn0266315 non_protein_coding_gene - - - CR44980 - CR44980 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085607 CG41311 - http://flybase.org/reports/FBgn0085607 protein_coding_gene - - - CG41311 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0261085 Syt12 Synaptotagmin 12 http://flybase.org/reports/FBgn0261085 protein_coding_gene clathrin binding ; GO:0030276 | inferred from biological aspect of ancestor with PANTHER:PTN000001285 calcium-dependent phospholipid binding ; GO:0005544 | inferred from biological aspect of ancestor with PANTHER:PTN000001283 syntaxin binding ; GO:0019905 | inferred from biological aspect of ancestor with PANTHER:PTN000001285 calcium ion binding ; GO:0005509 | inferred from biological aspect of ancestor with PANTHER:PTN000001283 regulation of neurotransmitter secretion ; GO:0046928 | inferred from electronic annotation with InterPro:IPR030537 long-term synaptic potentiation ; GO:0060291 | inferred from electronic annotation with InterPro:IPR030537 calcium ion-regulated exocytosis of neurotransmitter ; GO:0048791 | inferred from biological aspect of ancestor with PANTHER:PTN000001285 regulation of calcium ion-dependent exocytosis ; GO:0017158 | inferred from biological aspect of ancestor with PANTHER:PTN000001285 vesicle fusion ; GO:0006906 | inferred from biological aspect of ancestor with PANTHER:PTN000001285 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000001283 integral component of membrane ; GO:0016021 | inferred from sequence model "Syt12, Syt 12, dsyt12, syt12, CG10617" "IPR000008:C2 domain, IPR030537:Synaptotagmin-12" CG10617 27-Aug-18 DroID_v2018_08 "Drer\LOC570938, Drer\syt12" - "Cele\snt-4, Cele\snt-7" - Mmus\Syt12 "Hsap\SYT3, Hsap\SYT12, Hsap\SYT10, Hsap\SYT6, Hsap\SYT9" FBgn0044029 NOF\ORF NOF element ORF http://flybase.org/reports/FBgn0044029 transposable_element_gene - - - NOF\ORF - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051419 CG31419 - http://flybase.org/reports/FBgn0051419 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "CG5329, CG31419" - CG31419 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0283434 CG46277 - http://flybase.org/reports/FBgn0283434 protein_coding_gene - microtubule-based movement ; GO:0007018 | inferred from electronic annotation with InterPro:IPR025956 cytoplasmic dynein complex ; GO:0005868 | inferred from electronic annotation with InterPro:IPR025956 "CG46277, SdicC" "IPR001680:WD40 repeat, IPR025956:Cytoplasmic dynein 1 intermediate chain 1/2, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG46277 27-Aug-18 DroID_v2018_08 "Drer\dync1i2b, Drer\LOC103908626" - Cele\dyci-1 "Xtro\dync1i2, Xtro\dync1i1" "Mmus\Dync1i2, Mmus\Dync1i1" "Hsap\DYNC1I2, Hsap\DYNC1I1" FBgn0264374 lncRNA:CR43826 - http://flybase.org/reports/FBgn0264374 non_protein_coding_gene - - - CR43826 - CR43826 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259749 mmy mummy http://flybase.org/reports/FBgn0259749 protein_coding_gene UDP-N-acetylglucosamine diphosphorylase activity ; GO:0003977 | inferred from sequence or structural similarity UDP-N-acetylglucosamine diphosphorylase activity ; GO:0003977 | inferred from mutant phenotype "open tracheal system development ; GO:0007424 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype axonal fasciculation ; GO:0007413 | inferred from mutant phenotype embryonic epithelial tube formation ; GO:0001838 | inferred from mutant phenotype central nervous system development ; GO:0007417 | inferred from mutant phenotype cuticle chitin biosynthetic process ; GO:0006035 | inferred from mutant phenotype chitin-based cuticle development ; GO:0040003 | inferred from mutant phenotype chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | inferred from mutant phenotype regulation of tube size, open tracheal system ; GO:0035151 | inferred from mutant phenotype UDP-N-acetylglucosamine biosynthetic process ; GO:0006048 | inferred from biological aspect of ancestor with PANTHER:PTN000237224 extracellular matrix organization ; GO:0030198 | inferred from mutant phenotype" cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000237128 "mmy, cao, CG9535, cystic, mum, LD44264, BcDNA:LD24639, cyst, cys, l(2)k13717b, anon-WO0140519.242, mummy" "IPR002618:UDPGP family, IPR029044:Nucleotide-diphospho-sugar transferases" CG9535 27-Aug-18 DroID_v2018_08 "Drer\uap1, Drer\sec61a1, Drer\uap1l1, Drer\sec61a1l" Scer\QRI1 "Cele\C36A4.4, Cele\sec-61" "Xtro\uap1, Xtro\uap1l1, Xtro\sec61a1" "Mmus\Sec61a1, Mmus\Uap1l1, Mmus\Sec61a2, Mmus\Uap1" "Hsap\UAP1L1, Hsap\UAP1, Hsap\SEC61A2, Hsap\SEC61A1" FBgn0063380 snoRNA:U31:54Eb snoRNA:U31:54Eb http://flybase.org/reports/FBgn0063380 snoRNA_gene - - - "U31snoRNA, CR32897, snoRNA:U31:54Eb" - CR32897 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0067327 A23 A23 http://flybase.org/reports/FBgn0067327 gene - - - A23 - - 27-Aug-18 DroID_v2018_08 - - - - - - "eye color defective,lethal" pigment cell FBgn0015522 olf186-M olf186-M http://flybase.org/reports/FBgn0015522 - protein_coding_gene receptor binding ; GO:0005102 | inferred from electronic annotation with InterPro:IPR029325 molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG14489, olf186-M" IPR029325:IP3R-interacting domain CG14489 27-Aug-18 DroID_v2018_08 "Drer\tespa1, Drer\ccdc129, Drer\ssfa2" - - - "Mmus\Ccdc129, Mmus\Tespa1, Mmus\Ssfa2" "Hsap\CCDC129, Hsap\SSFA2, Hsap\TESPA1" viable FBgn0002814 ms(1)V73 male sterile (1) V73 http://flybase.org/reports/FBgn0002814 - gene - - - ms(1)V73 - - 27-Aug-18 DroID_v2018_08 - - - - - - male sterile FBgn0035926 CG5804 - http://flybase.org/reports/FBgn0035926 protein_coding_gene fatty-acyl-CoA binding ; GO:0000062 | inferred from electronic annotation with InterPro:IPR000582 - - "BcDNA:RE05521, CG5804" "IPR000582:Acyl-CoA-binding protein, ACBP, IPR014352:FERM/acyl-CoA-binding protein, 3-helical bundle" CG5804 27-Aug-18 DroID_v2018_08 "Drer\dbi, Drer\mettl23, Drer\acbd6, Drer\acbd7, Drer\acbd4, Drer\zgc:92030, Drer\acbd5b, Drer\LOC103909942" Scer\ACB1 "Cele\acbp-6, Cele\acbp-3, Cele\acbp-5, Cele\maa-1, Cele\acbp-4, Cele\acbp-1" "Xtro\acbd7, Xtro\acbd5, Xtro\mettl23, Xtro\eci2, Xtro\acbd6" "Mmus\Dbi, Mmus\Acbd6, Mmus\Acbd4, Mmus\Acbd5, Mmus\Dbil5, Mmus\Acbd7, Mmus\Eci2, Mmus\Mettl23" "Hsap\ACBD4, Hsap\ECI2, Hsap\DBI, Hsap\METTL23, Hsap\ACBD6, Hsap\ACBD5, Hsap\ACBD7" viable FBgn0031550 IFT57 Intraflagellar transport 57 http://flybase.org/reports/FBgn0031550 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cilium assembly ; GO:0060271 | inferred from sequence or structural similarity with MGI:MGI:1921166 regulation of apoptotic process ; GO:0042981 | inferred from sequence or structural similarity with UniProtKB:Q9NWB7 apoptotic process ; GO:0006915 | inferred from sequence or structural similarity with UniProtKB:Q9NWB7 cilium assembly ; GO:0060271 | inferred from sequence model intraciliary transport ; GO:0042073 | inferred from biological aspect of ancestor with PANTHER:PTN000410691 activation of cysteine-type endopeptidase activity involved in apoptotic process ; GO:0006919 | inferred from sequence or structural similarity with UniProtKB:Q9NWB7 cilium assembly ; GO:0060271 | inferred from biological aspect of ancestor with PANTHER:PTN000410691 Golgi apparatus ; GO:0005794 | inferred from biological aspect of ancestor with PANTHER:PTN000410691 intraciliary transport particle B ; GO:0030992 | inferred from biological aspect of ancestor with PANTHER:PTN000410691 ciliary basal body ; GO:0036064 | inferred from sequence or structural similarity with UniProtKB:Q8BXG3 cilium ; GO:0005929 | inferred from sequence or structural similarity with MGI:MGI:1921166 cilium ; GO:0005929 | inferred from biological aspect of ancestor with PANTHER:PTN000410691 intraciliary transport particle B ; GO:0030992 | inferred from sequence or structural similarity with MGI:MGI:1921166 centrosome ; GO:0005813 | inferred from biological aspect of ancestor with PANTHER:PTN000410691 "IFT57, Hippi, CHE-13, CG8853, che-13, IFT55, Che-13" IPR019530:Intra-flagellar transport protein 57 CG8853 27-Aug-18 DroID_v2018_08 Drer\ift57 - Cele\che-13 Xtro\ift57 Mmus\Ift57 Hsap\IFT57 FBgn0024861 l(3)96Ba lethal (3) 96Ba http://flybase.org/reports/FBgn0024861 - gene - - - l(3)96Ba - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0267009 lncRNA:CR45453 - http://flybase.org/reports/FBgn0267009 non_protein_coding_gene - - - CR45453 - CR45453 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065397 l(2)SH1612 lethal (2) SH1612 http://flybase.org/reports/FBgn0065397 gene - - - "l(2)SH1612, l(2)SH2 1612" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0004903 Rb97D Ribonuclear protein at 97D http://flybase.org/reports/FBgn0004903 - protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity spermatid development ; GO:0007286 | inferred from mutant phenotype - "rbf, Rb97D1, ms(3)03445, R16, Hrb97D, CG6354, Rb97D, rb97d, RBP97D" IPR000504:RNA recognition motif domain CG6354 27-Aug-18 DroID_v2018_08 "Drer\hnrnpa1a, Drer\msi2b, Drer\rbm24a, Drer\srsf10a, Drer\syncripl, Drer\trnau1apb, Drer\raly, Drer\ncl, Drer\trnau1apa, Drer\rbm24b, Drer\msi2a, Drer\hnrpdl, Drer\hnrnpa1b, Drer\dazap1, Drer\dazl, Drer\hnrnpa3, Drer\eif4ba, Drer\zcrb1, Drer\cirbpa, Drer\hnrnpd, Drer\syncrip, Drer\hnrnpa0l, Drer\zgc:55733, Drer\hnrnpa0b, Drer\eif4h, Drer\hnrnpa0a, Drer\hnrnpabb, Drer\hnrnpc, Drer\hnrnpaba, Drer\ncoa5, Drer\wu:fq32h04, Drer\rbm34" "Scer\CWC2, Scer\NGR1, Scer\MRN1, Scer\NOP6, Scer\MUD1, Scer\NAM8, Scer\HRP1, Scer\NAB6, Scer\NOP12" "Cele\sqd-1, Cele\H28G03.1, Cele\msi-1, Cele\hrp-1" "Xtro\ralyl, Xtro\trnau1ap, Xtro\rbm34, Xtro\raly, Xtro\hnrnpdl, Xtro\hnrnpa1, Xtro\hnrnpa0, Xtro\dazap1, Xtro\hnrnpa3, Xtro\hnrnpab, Xtro\hnrnpc, Xtro\hnrnpa2b1, Xtro\cirbp, Xtro\dazl, Xtro\eif4h, Xtro\eif4b, Xtro\hnrnpd, Xtro\msi1" "Mmus\Hnrnpab, Mmus\Rbm38, Mmus\Dazap1, Mmus\Eif4h, Mmus\Boll, Mmus\Ncl, Mmus\Rbm31y, Mmus\Hnrnpa0, Mmus\Tra2b, Mmus\Hnrnpa3, Mmus\Srsf12, Mmus\Hnrnpd, Mmus\Rbm34, Mmus\Zcrb1, Mmus\Cirbp, Mmus\Msi1, Mmus\Eif4b, Mmus\Trnau1ap, Mmus\Syncrip, Mmus\Rbm24, Mmus\Msi2, Mmus\Dazl, Mmus\Hnrnpa2b1, Mmus\Srsf10, Mmus\Gm21379, Mmus\Hnrnpc, Mmus\Raly, Mmus\Slirp, Mmus\Hnrnpa1, Mmus\Hnrnpr, Mmus\Hnrnpdl" "Hsap\RBM34, Hsap\BOLL, Hsap\DAZAP1, Hsap\NCL, Hsap\HNRNPC, Hsap\DAZ4, Hsap\HNRNPA3, Hsap\RALY, Hsap\DAZ1, Hsap\DAZ2, Hsap\SLIRP, Hsap\RBM24, Hsap\RBMXL3, Hsap\HNRNPD, Hsap\EIF4H, Hsap\TRNAU1AP, Hsap\MSI2, Hsap\HNRNPA1L2, Hsap\CIRBP, Hsap\EIF4B, Hsap\RBM3, Hsap\HNRNPR, Hsap\HNRNPDL, Hsap\DAZ3, Hsap\MSI1, Hsap\SYNCRIP, Hsap\SRSF10, Hsap\HNRNPA0, Hsap\DAZL, Hsap\RALYL, Hsap\HNRNPA2B1, Hsap\HNRNPAB, Hsap\HNRNPA1, Hsap\HNRNPCL1, Hsap\RBM38" embryonic stage -- adult stage "male sterile,recessive" "nucleus & spermatid,axoneme" FBgn0000148 aw awry http://flybase.org/reports/FBgn0000148 - gene - - - aw - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive,fertile" wing FBgn0065590 l(2)SH0905 lethal (2) SH0905 http://flybase.org/reports/FBgn0065590 gene - - - "l(2)SH0905, l(2)SH2 0905" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0005402 l(1)10Bn lethal (1) 10Bn http://flybase.org/reports/FBgn0005402 - gene - - - "l(1)C248, l(1)L19, l(1)10Bn" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" imaginal disc FBgn0016800 l(1)K1 lethal (1) K1 http://flybase.org/reports/FBgn0016800 - gene - - - "l(1)K1, K1" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0262962 CG43273 - http://flybase.org/reports/FBgn0262962 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43273 - CG43273 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031255 BBS8 Bardet-Biedl syndrome 8 http://flybase.org/reports/FBgn0031255 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cilium assembly ; GO:0060271 | inferred from sequence model inferred from expression pattern cilium ; GO:0005929 | inferred from sequence or structural similarity with HGNC:20087 BBSome ; GO:0034464 | inferred from sequence or structural similarity with HGNC:20087 cilium ; GO:0005929 | inferred by curator from GO:0060271 "BBS2, CG13691, BBS8" "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat" CG13691 27-Aug-18 DroID_v2018_08 Drer\ttc8 Scer\CDC27 Cele\bbs-8 Xtro\ttc8 Mmus\Ttc8 Hsap\TTC8 viable FBgn0020879 anon-43Ba anon-43Ba http://flybase.org/reports/FBgn0020879 - gene - - - "tuII, anon-43Ba" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0013536 l(2)ry36 lethal (2) ry36 http://flybase.org/reports/FBgn0013536 - gene - - - "l(2)36, l(2)ry36" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0283484 CLIP-190::Rnor\Clip1 - http://flybase.org/reports/FBgn0283484 engineered_fusion_gene - - - CLIP-190::Rnor\Clip1 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260340 GSd424 - http://flybase.org/reports/FBgn0260340 gene - - - GSd424 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0046707 GIIIE GIIIE http://flybase.org/reports/FBgn0046707 gene phospholipase A2 activity ; GO:0004623 | non-traceable author statement - extracellular region ; GO:0005576 | non-traceable author statement "dGIIIE, GIIIE" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0042135 CG18812 - http://flybase.org/reports/FBgn0042135 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG12040, CG18813, CG18812" "IPR001251:CRAL-TRIO lipid binding domain, IPR002589:Macro domain" CG18812 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-219a4.6, Drer\macrod1, Drer\LOC100148704, Drer\gdap2, Drer\macrod2, Drer\si:ch211-219a4.3, Drer\h2afy2" - Cele\B0035.3 "Xtro\parp14.2, Xtro\gdap2, Xtro\h2afy, Xtro\parp9, Xtro\h2afy2" "Mmus\Parp14, Mmus\Macrod2, Mmus\Macrod1, Mmus\Gdap2, Mmus\Parp9, Mmus\H2afy2, Mmus\H2afy" "Hsap\H2AFY, Hsap\PARP14, Hsap\GDAP2, Hsap\PARP9, Hsap\PARP15, Hsap\MACROD2, Hsap\H2AFY2, Hsap\MACROD1" viable FBgn0035107 mri mrityu http://flybase.org/reports/FBgn0035107 protein_coding_gene glycerol kinase activity ; GO:0004370 | NOT inferred from key residues sensory perception of touch ; GO:0050975 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern lateral inhibition ; GO:0046331 | inferred from mutant phenotype autophagic cell death ; GO:0048102 | inferred from expression pattern cellular_component ; GO:0005575 | no biological data available "CG1216, mri, Mri" "IPR000210:BTB/POZ domain, IPR011333:SKP1/BTB/POZ domain" CG1216 27-Aug-18 DroID_v2018_08 "Drer\kctd6a, Drer\btbd10b, Drer\kctd4, Drer\kctd20, Drer\btbd10a, Drer\kctd6b" - "Cele\btbd-10, Cele\ZC239.15, Cele\F22E5.8" "Xtro\btbd10, Xtro\kctd6" "Mmus\Btbd10, Mmus\Kctd20, Mmus\Kctd6" "Hsap\BTBD10, Hsap\KCTD11, Hsap\KCTD20, Hsap\KCTD6" "viable,visible,neuroanatomy defective,touch sensitivity defective" "chaeta,supernumerary,mesothoracic tergum,dorsal multidendritic neuron ddaA | larval stage,sensory dendrite | larval stage, with Dcr-2UAS.cDa, 1003.3" FBgn0019743 l(1)8E lethal (1) 8E http://flybase.org/reports/FBgn0019743 - gene - - - "l(1)8, l(1)8E" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0265382 lncRNA:CR44323 - http://flybase.org/reports/FBgn0265382 non_protein_coding_gene - - - CR44323 - CR44323 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030572 mRpS25 mitochondrial ribosomal protein S25 http://flybase.org/reports/FBgn0030572 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:P82663 structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with EMBL:AI243774 inferred from sequence or structural similarity with EMBL:AW249185 translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:P82663 translation ; GO:0006412 | inferred from sequence or structural similarity with EMBL:AI243774 inferred from sequence or structural similarity with EMBL:AW249185 mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial small ribosomal subunit ; GO:0005763 | traceable author statement mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:P82663 mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with EMBL:AI243774 inferred from sequence or structural similarity with EMBL:AW249185 "CG14413, MRP-S25, MrpS25, mRpS25, 25mRps" "IPR007741:Ribosomal protein/NADH dehydrogenase domain, IPR012336:Thioredoxin-like fold" CG14413 27-Aug-18 DroID_v2018_08 Drer\mrps25 Scer\MRP49 Cele\mrps-25 Xtro\mrps25 Mmus\Mrps25 Hsap\MRPS25 "viable,visible" trichogen cell FBgn0011611 l(1)I33e16 lethal (1) I33e16 http://flybase.org/reports/FBgn0011611 FBgn0010206 gene - - - "l(1)33e16, l(1)I33e16" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0020359 anon-1H11 anon-1H11 http://flybase.org/reports/FBgn0020359 - gene - - - "1H11, anon-1H11" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0015543 snoRNA:Me28S-A1322 - http://flybase.org/reports/FBgn0015543 - snoRNA_gene - - - "Dm-797, snoR797, Z1, snoRNA Z1, CR32905, snoRNA:Me28S-A1322, Me28S-A1322(Z1), snoRNA:Z1, SnR61, DmSnR61c, chr2R:7409020..7409115" - CR32905 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0041159 dos::Hsap\GAB1 GAB1 http://flybase.org/reports/FBgn0041159 engineered_fusion_gene - - - dos::Hsap\GAB1 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0013447 fs(2)ry11 fs(2)ry11 http://flybase.org/reports/FBgn0013447 - gene - - - "fs(2)11, fs(2)ry11" - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,lethal - all die before end of embryonic stage,rescuable maternal effect,some die during embryonic stage" FBgn0085237 CG34208 - http://flybase.org/reports/FBgn0085237 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34208 - CG34208 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002055 l(2)38Aa lethal (2) 38Aa http://flybase.org/reports/FBgn0002055 - gene - - - "l(2)E124P, l(2)38Aa" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0017407 diva divagari http://flybase.org/reports/FBgn0017407 - gene molecular_function ; GO:0003674 | no biological data available axon guidance ; GO:0007411 | inferred from mutant phenotype brain development ; GO:0007420 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available diva - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,male sterile" "photoreceptor cell R1 & axon,photoreceptor cell R2 & axon,photoreceptor cell R3 & axon,photoreceptor cell R4 & axon,photoreceptor cell R5 & axon,photoreceptor cell R6 & axon,lamina anlage,precursor,larval inner optic anlage,larval outer optic anlage" FBgn0051457 CG31457 - http://flybase.org/reports/FBgn0051457 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 protein phosphatase 1 binding ; GO:0008157 | inferred from physical interaction with flw inferred from physical interaction with Pp1-13C inferred from physical interaction with Pp1α-96A inferred from physical interaction with Pp1-87B - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 "CG4639, CG31457" "IPR012934:Zinc finger, AD-type" CG31457 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0034649 PIG-M Phosphatidylinositol glycan anchor biosynthesis class M http://flybase.org/reports/FBgn0034649 protein_coding_gene "transferase activity, transferring hexosyl groups ; GO:0016758 | inferred from electronic annotation with InterPro:IPR007704" GPI anchor biosynthetic process ; GO:0006506 | inferred from electronic annotation with InterPro:IPR007704 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR007704 "CG9865, Dromel_CG9865_FBtr0071680_cx9c_morf, PIG-M" "IPR007704:Mannosyltransferase, DXD" CG9865 27-Aug-18 DroID_v2018_08 Drer\pigm Scer\GPI14 Cele\B0491.1 Xtro\pigm Mmus\Pigm Hsap\PIGM FBgn0015725 Eig82F Ecdysone induced gene at 82F http://flybase.org/reports/FBgn0015725 - gene - - - Eig82F - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085499 CG40600 - http://flybase.org/reports/FBgn0085499 protein_coding_gene - - - CG40600 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040763 CG18336 - http://flybase.org/reports/FBgn0040763 protein_coding_gene - - - "CG13212, CG18336" IPR018902:Uncharacterised protein family UPF0573/UPF0605 CG18336 27-Aug-18 DroID_v2018_08 Drer\fam166b - "Cele\T09D3.8, Cele\F49C5.10" - "Mmus\Fam166b, Mmus\Fam166a" "Hsap\FAM166B, Hsap\FAM166A" viable FBgn0038306 Art3 Arginine methyltransferase 3 http://flybase.org/reports/FBgn0038306 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 methyltransferase activity ; GO:0008168 | inferred from electronic annotation with InterPro:IPR025799 peptidyl-arginine methylation ; GO:0018216 | inferred from sequence or structural similarity with RGD:620413 - "DART3, CG6563, Art3" "IPR013087:Zinc finger C2H2-type, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase, IPR025799:Protein arginine N-methyltransferase" CG6563 27-Aug-18 DroID_v2018_08 "Drer\LOC556054, Drer\prmt8b, Drer\prmt1, Drer\prmt6, Drer\prmt3" "Scer\HMT1, Scer\CRG1" Cele\C37A2.6 "Xtro\prmt3, Xtro\prmt8, Xtro\prmt6, Xtro\prmt1" "Mmus\Prmt2, Mmus\Ndufaf5, Mmus\Prmt3, Mmus\Prmt8, Mmus\Prmt6, Mmus\Prmt1" "Hsap\PRMT2, Hsap\ETFBKMT, Hsap\NDUFAF5, Hsap\PRMT3, Hsap\PRMT1, Hsap\PRMT6, Hsap\PRMT8" "viable,fertile" FBgn0019852 anon-XII anon-XII http://flybase.org/reports/FBgn0019852 - gene - - - "XII, anon-XII" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0024941 RSG7 Regulator of G-protein signaling 7 http://flybase.org/reports/FBgn0024941 "FBtr0074350, FBpp0074124" protein_coding_gene signal transducer activity ; GO:0004871 | inferred from electronic annotation with InterPro:IPR015898 GTPase activator activity ; GO:0005096 | inferred from biological aspect of ancestor with PANTHER:PTN000090250 intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR000591 regulation of G-protein coupled receptor protein signaling pathway ; GO:0008277 | inferred from sequence or structural similarity with WB:WBGene00001179 heterotrimeric G-protein complex ; GO:0005834 | inferred from electronic annotation with InterPro:IPR015898 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000090250 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000090250 "RGS7, dRGS7, CG9108, RSG7" "IPR015898:G-protein gamma-like domain, IPR000591:DEP domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR016137:RGS domain, IPR024066:RGS, subdomain 1, IPR034483:Regulator of G-protein signalling Egl-10" CG9108 27-Aug-18 DroID_v2018_08 "Drer\rgs19, Drer\rgs1, Drer\rgs5b, Drer\rgs12b, Drer\rgs4, Drer\rgs13, Drer\rgs8, Drer\si:ch211-152p11.4, Drer\si:ch211-196h16.12, Drer\rgs7b, Drer\rgs18, Drer\rgs12a, Drer\rgs3a, Drer\si:ch211-117l17.5, Drer\rgs14b, Drer\rgs9b, Drer\axin1, Drer\rgs11, Drer\rgs17, Drer\rgs7a, Drer\rgs6, Drer\rgs5a, Drer\si:ch211-117l17.6, Drer\rgs14a, Drer\axin2, Drer\rgs2, Drer\rgs16, Drer\grid2ipb" "Scer\SST2, Scer\RGS2" "Cele\eat-16, Cele\rgs-6, Cele\rgs-4, Cele\egl-10" "Xtro\rgs10, Xtro\rgs6, Xtro\rgs16, Xtro\rgs1, Xtro\rgs17, Xtro\xarp, Xtro\rgs20, Xtro\rgs2, Xtro\axin1, Xtro\rgs19, Xtro\rgs5, Xtro\cep112, Xtro\rgs4, Xtro\rgs3, Xtro\rgs18" "Mmus\Rgs3, Mmus\Rgs9, Mmus\Rgs14, Mmus\Rgs2, Mmus\Axin1, Mmus\Rgs11, Mmus\Rgs8, Mmus\Rgs12, Mmus\Rgs5, Mmus\Rgs1, Mmus\Rgs20, Mmus\Rgsl1, Mmus\Rgs17, Mmus\Rgs4, Mmus\Rgs16, Mmus\Rgs7, Mmus\Rgs18, Mmus\Rgs13, Mmus\Rgs10, Mmus\Axin2, Mmus\Rgs19, Mmus\Rgs6" "Hsap\AXIN2, Hsap\RGS17, Hsap\RGS12, Hsap\RGS14, Hsap\RGS20, Hsap\RGS6, Hsap\RGS3, Hsap\RGS21, Hsap\RGS11, Hsap\RGS2, Hsap\RGS19, Hsap\RGS18, Hsap\RGS16, Hsap\RGS7, Hsap\RGS13, Hsap\RGS10, Hsap\RGS8, Hsap\RGS5, Hsap\AXIN1, Hsap\RGS4, Hsap\RGS9, Hsap\RGS1, Hsap\RGSL1" "partially lethal - majority die,some die during pupal stage" DRSC20274 EK 0.088714279 0.479881958 -0.166699895 1.755589105 -1.513719552 -0.695144892 FBgn0261686 CG42733 - http://flybase.org/reports/FBgn0261686 protein_coding_gene - - - "CG12901, Tes85-2, CG42733" - CG42733 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0265297 pAbp poly(A) binding protein http://flybase.org/reports/FBgn0265297 protein_coding_gene poly(A) binding ; GO:0008143 | traceable author statement poly(A) binding ; GO:0008143 | inferred from sequence or structural similarity with SGD:S000000967 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity mRNA 3'-UTR binding ; GO:0003730 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Paip2 poly(A) binding ; GO:0008143 | non-traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8SY33 "positive regulation of translation ; GO:0045727 | inferred from genetic interaction with grk regulation of compound eye photoreceptor development ; GO:0045314 | inferred from genetic interaction with pAbp male meiosis cytokinesis ; GO:0007112 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype oocyte development ; GO:0048599 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype spermatid nucleus differentiation ; GO:0007289 | inferred from mutant phenotype positive regulation of translation ; GO:0045727 | traceable author statement oogenesis ; GO:0048477 | inferred from mutant phenotype chemical synaptic transmission ; GO:0007268 | inferred from mutant phenotype negative regulation of neuron death ; GO:1901215 | inferred from genetic interaction with pAbp dorsal/ventral pattern formation ; GO:0009953 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 male meiosis ; GO:0007140 | inferred from mutant phenotype" lipid particle ; GO:0005811 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay intracellular ribonucleoprotein complex ; GO:0030529 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "PABP, pabp, pAbp, CG5119, Pabp, dPABP, pAB, PAbp, duo, l(2)k10109, anon-EST:Posey247, anon-EST:Posey249, BcDNA:LD24412, PABPC1, PABP55B, pABP, l(2)SH1908, l(2)SH2 1908, anon-EST:fe2E5, CG16803" "IPR000504:RNA recognition motif domain, IPR002004:Polyadenylate-binding protein/Hyperplastic disc protein, IPR006515:Polyadenylate binding protein, human types 1, 2, 3, 4" CG5119 27-Aug-18 DroID_v2018_08 "Drer\pabpc1b, Drer\pabpc1l, Drer\LOC100537585, Drer\pabpc1a, Drer\pabpc4, Drer\ncl, Drer\zgc:171310" "Scer\MIP6, Scer\PES4, Scer\PAB1" "Cele\pab-2, Cele\pab-1" "Xtro\pabpc1l, Xtro\pabpc1, Xtro\pabpc4" "Mmus\Pabpc6, Mmus\Pabpc4l, Mmus\Pabpc2, Mmus\Pabpc5, Mmus\Pabpc1l, Mmus\Pabpc1, Mmus\Pabpc4" "Hsap\PABPC1L2B, Hsap\PABPC4, Hsap\PABPC3, Hsap\PABPC4L, Hsap\PABPC1, Hsap\PABPC5, Hsap\PABPC1L2A, Hsap\PABPC1L" " oogenesis stage && adult stage | female , embryonic stage -- adult stage " ovary

DRSC07659 IEK 1.096973612 -6.200961709 -2.273655693 -3.389501586 3.14274607 2.47206588 FBgn0030841 CG8568 - http://flybase.org/reports/FBgn0030841 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG8568 IPR031941:Domain of unknown function DUF4773 CG8568 27-Aug-18 DroID_v2018_08 - - Cele\C09D4.2 Xtro\LOC100498624 "Mmus\Hrc, Mmus\Akap5" - "lethal - all die before end of pupal stage,some die during pupal stage,viable" FBgn0265316 lncRNA:CR44289 - http://flybase.org/reports/FBgn0265316 non_protein_coding_gene - - - "CR44289, lincRNA.872" - CR44289 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002174 l(2)tid lethal (2) tumorous imaginal discs http://flybase.org/reports/FBgn0002174 FBgn0034896 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR012724 unfolded protein binding ; GO:0051082 | inferred from electronic annotation with InterPro:IPR001305, InterPro:IPR008971, InterPro:IPR012724 heat shock protein binding ; GO:0031072 | inferred from electronic annotation with InterPro:IPR001305 patched binding ; GO:0005113 | inferred from physical interaction with ptc" "protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR008971, InterPro:IPR012724 response to heat ; GO:0009408 | inferred from electronic annotation with InterPro:IPR012724 smoothened signaling pathway ; GO:0007224 | inferred from genetic interaction with ptc inferred from physical interaction with ptc sleep ; GO:0030431 | inferred from expression pattern mitochondrion organization ; GO:0007005 | inferred from biological aspect of ancestor with PANTHER:PTN001180543" mitochondrion ; GO:0005739 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from sequence or structural similarity inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "lethal (2) tumorous imaginal discs, l(2)tumorous imaginal discs, TID56, DnaJ, tid, cDNA 10D, l(2)tumorous disc, l(2)tud, l(2)td, l(2)701, CG5504, l(2)tid" "IPR018253:DnaJ domain, conserved site, IPR001305:Heat shock protein DnaJ, cysteine-rich domain, IPR001623:DnaJ domain, IPR002939:Chaperone DnaJ, C-terminal, IPR008971:HSP40/DnaJ peptide-binding, IPR012724:Chaperone DnaJ" CG5504 27-Aug-18 DroID_v2018_08 "Drer\dnaja3a, Drer\dnaja3b, Drer\LOC554962, Drer\dnajc16, Drer\dnajc16l, Drer\dnajc24" "Scer\ERJ5, Scer\APJ1, Scer\JJJ1, Scer\MDJ1, Scer\SCJ1" Cele\dnj-10 "Xtro\dnajc24, Xtro\dnajc16, Xtro\dnaja3" "Mmus\Dnaja3, Mmus\Dnajc16, Mmus\Dnajc24" "Hsap\DNAJC16, Hsap\DNAJA3, Hsap\DNAJC24" " larval stage , adult stage , embryonic stage -- adult stage " "wild-type,lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal,tumorigenic" "wing disc,imaginal disc" FBgn0058384 CG40384 - http://flybase.org/reports/FBgn0058384 protein_coding_gene - - - CG40384 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264081 CG43750 - http://flybase.org/reports/FBgn0264081 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43750 - CG43750 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040547 CG14706 - http://flybase.org/reports/FBgn0040547 protein_coding_gene - - - CG14706 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060966 l(3)S030901b lethal (3) S030901b http://flybase.org/reports/FBgn0060966 gene - - - "0309/01, l(3)S030901b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0027654 jdp jdp http://flybase.org/reports/FBgn0027654 - protein_coding_gene unfolded protein binding ; GO:0051082 | inferred from sequence or structural similarity with ECOGENE:EG10240 protein folding ; GO:0006457 | inferred from sequence or structural similarity with ECOGENE:EG10240 cellular_component ; GO:0005575 | no biological data available "dJDP, p25a, CG2239, jdp, JDP" IPR001623:DnaJ domain CG2239 27-Aug-18 DroID_v2018_08 "Drer\dnajc30b, Drer\dnajc12, Drer\dnajc4, Drer\dnajc30" "Scer\CAJ1, Scer\DJP1" Cele\K07F5.16 "Xtro\dnajc4, Xtro\dnajc17, Xtro\dnajc12" "Mmus\Dnajc12, Mmus\Dnajc17" "Hsap\DNAJC12, Hsap\DNAJC17" "viable,fertile" FBgn0003331 scg scrambled egg http://flybase.org/reports/FBgn0003331 - gene - - - scg - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035964 Dhpr Dihydropteridine reductase http://flybase.org/reports/FBgn0035964 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR020904 - - "CG4665, DHPR, Dhpr" "IPR016040:NAD(P)-binding domain, IPR020904:Short-chain dehydrogenase/reductase, conserved site, IPR002347:Short-chain dehydrogenase/reductase SDR" CG4665 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-40h17.4, Drer\qdprb2, Drer\qdpra, Drer\zgc:171517, Drer\qdprb1" - Cele\qdpr-1 Xtro\qdpr Mmus\Qdpr Hsap\QDPR adult stage adult head

FBgn0051969 CR31969 - http://flybase.org/reports/FBgn0051969 non_protein_coding_gene - - - "BcDNA:LP03459, CR31969" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0016857 l(1)N4 lethal (1) N4 http://flybase.org/reports/FBgn0016857 - gene - - - "l(1)N4, N4" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0053237 Ste:CG33237 Ste:CG33237 http://flybase.org/reports/FBgn0053237 protein_coding_gene protein kinase regulator activity ; GO:0019887 | inferred from mutant phenotype regulation of protein serine/threonine phosphatase activity ; GO:0080163 | inferred from mutant phenotype protein kinase CK2 complex ; GO:0005956 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG32605, CG33237, Ste:CG33237" "IPR000704:Casein kinase II, regulatory subunit, IPR016149:Casein kinase II, regulatory subunit, alpha-helical" CG33237 27-Aug-18 DroID_v2018_08 Drer\csnk2b "Scer\CKB2, Scer\CKB1" Cele\kin-10 Xtro\csnk2b Mmus\Csnk2b Hsap\CSNK2B FBgn0040610 CG14263 - http://flybase.org/reports/FBgn0040610 protein_coding_gene - - - CG14263 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0003743 trb thread bristle http://flybase.org/reports/FBgn0003743 - gene - - - trb - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,male fertile,viable,male,visible,body color defective" "macrochaeta,microchaeta,wing,wing vein,trident" FBgn0015793 Rab19 Rab19 http://flybase.org/reports/FBgn0015793 - protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR005225 protein binding ; GO:0005515 | inferred from physical interaction with GCC88, cbs GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11 GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with plx" vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 neuronal cell body ; GO:0043025 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay synapse ; GO:0045202 | inferred from direct assay vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 recycling endosome ; GO:0055037 | inferred from direct assay "AAF50452, DmRab19, DRabRP3, DRABR3, Rab-r3, CG7062, Rab19, Rab19/RP3, rab19, Rab19s, Rab-RP3, O18339" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG7062 27-Aug-18 DroID_v2018_08 "Drer\rab1aa, Drer\rab43, Drer\rab33a, Drer\zgc:171927, Drer\rabl6a, Drer\rab1bb, Drer\zgc:101559, Drer\rabl6b, Drer\rab33ba, Drer\rab12, Drer\rab19, Drer\rab1ab, Drer\rab1ba" "Scer\YPT1, Scer\YPT31, Scer\YPT32" Cele\rab-19 "Xtro\rab1a, Xtro\rab19, Xtro\rab33b, Xtro\rabl6, Xtro\rab33a" "Mmus\Rabl6, Mmus\Rab43, Mmus\Rab12, Mmus\Rab19, Mmus\Rab33b, Mmus\Rab1b, Mmus\Rab33a, Mmus\Rab1a" "Hsap\RAB33B, Hsap\RAB12, Hsap\RABL6, Hsap\RAB1B, Hsap\RAB19, Hsap\RAB1A, Hsap\ISY1, Hsap\RAB43, Hsap\RAB33A" viable FBgn0262535 CG43089 - http://flybase.org/reports/FBgn0262535 protein_coding_gene - "ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from electronic annotation with InterPro:IPR016072, InterPro:IPR016073" - "CG43089, lincRNA.427" "IPR011333:SKP1/BTB/POZ domain, IPR016073:SKP1 component, POZ domain, IPR001232:S-phase kinase-associated protein 1-like" CG43089 27-Aug-18 DroID_v2018_08 Drer\skp1 Scer\SKP1 "Cele\skr-17, Cele\skr-6, Cele\skr-16, Cele\skr-15, Cele\skr-4, Cele\skr-1, Cele\skr-10, Cele\skr-12, Cele\skr-19, Cele\skr-21, Cele\skr-14, Cele\skr-9, Cele\skr-3, Cele\skr-18, Cele\skr-7, Cele\skr-5, Cele\skr-20, Cele\skr-8, Cele\skr-13, Cele\skr-2" Xtro\skp1 Mmus\Skp1a Hsap\SKP1 FBgn0065607 l(2)SH0843 lethal (2) SH0843 http://flybase.org/reports/FBgn0065607 gene - - - "l(2)SH0843, l(2)SH2 0843" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0038582 CG7988 - http://flybase.org/reports/FBgn0038582 protein_coding_gene molecular_function ; GO:0003674 | no biological data available circadian rhythm ; GO:0007623 | inferred from sequence or structural similarity with UniProtKB:Q8GWZ6 cellular_component ; GO:0005575 | no biological data available CG7988 "IPR012942:Sensitivity To Red Light Reduced-like, SRR1" CG7988 27-Aug-18 DroID_v2018_08 Drer\srrd Scer\BER1 - Xtro\srrd Mmus\Srrd Hsap\SRRD viable FBgn0058315 CG40315 - http://flybase.org/reports/FBgn0058315 protein_coding_gene - - - CG40315 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0028585 l(3)rI165 lethal (3) rI165 http://flybase.org/reports/FBgn0028585 gene - - - "l(?)rI165, l(3)rI165" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0051451 lncRNA:CR31451 - http://flybase.org/reports/FBgn0051451 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "gh16531, anon-EST:Posey277, BcDNA:GH16531, CG31451, CR31451" - CR31451 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0054012 CG34012 - http://flybase.org/reports/FBgn0054012 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BP1014, CG34012" - CG34012 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0058263 MFS17 Major Facilitator Superfamily Transporter 17 http://flybase.org/reports/FBgn0058263 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 anion transport ; GO:0006820 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000910672 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 "bs24e02.y1, BEST:LD07241, CG40263, MFS17" "IPR011701:Major facilitator superfamily, IPR027378:Cyclic nucleotide-regulated ion channel, N-terminal domain, IPR020846:Major facilitator superfamily domain" CG40263 27-Aug-18 DroID_v2018_08 "Drer\slc17a5, Drer\si:ch1073-513e17.1" "Scer\THI73, Scer\TNA1, Scer\DAL5, Scer\YIL166C" "Cele\F56A4.12, Cele\C01B4.8, Cele\C35A5.3, Cele\F10C2.7, Cele\T22F3.11, Cele\slc-17.3, Cele\M162.5, Cele\slc-17.1, Cele\T28H11.8, Cele\H11E01.2, Cele\T19D12.9, Cele\F59A1.13, Cele\Y19D10A.11, Cele\slc-17.5, Cele\C18H9.5, Cele\slc-17.2, Cele\C01B4.7, Cele\slc-17.8, Cele\C39E9.7, Cele\Y19D10A.5, Cele\T22F3.10, Cele\F44E7.7, Cele\T22F3.8, Cele\M117.1, Cele\Y19D10A.8, Cele\Y15E3A.4, Cele\slc-17.6, Cele\T02B11.6, Cele\T27D12.1, Cele\F11A5.9, Cele\R10D12.1, Cele\K08C7.1, Cele\T19D12.10, Cele\slc-17.4, Cele\Y19D10A.4, Cele\D1046.4, Cele\slc-17.9, Cele\Y4C6B.4, Cele\F56A4.10, Cele\cima-1, Cele\Y4C6B.3, Cele\T01H3.3, Cele\W04C9.6, Cele\slc-17.7, Cele\K11G9.5, Cele\C18D1.2, Cele\T22F3.7, Cele\Y51B9A.6, Cele\F41C3.2" - "Mmus\Slc17a1, Mmus\Slc17a2, Mmus\Slc17a4, Mmus\Slc17a5, Mmus\Slc17a3" "Hsap\SLC17A4, Hsap\SLC17A2, Hsap\SLC17A1, Hsap\SLC17A5, Hsap\SLC17A3" FBgn0035047 Pof Painting of fourth http://flybase.org/reports/FBgn0035047 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity RNA binding ; GO:0003723 | non-traceable author statement chromatin binding ; GO:0003682 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with egg - autosome ; GO:0030849 | inferred from direct assay chromosome ; GO:0005694 | inferred from direct assay "Pof, cg3691, CG3691, POF, pof" IPR000504:RNA recognition motif domain CG3691 27-Aug-18 DroID_v2018_08 - - - - - - "viable,wild-type" FBgn0065581 l(2)SH0941 lethal (2) SH0941 http://flybase.org/reports/FBgn0065581 gene - - - "l(2)SH0941, l(2)SH2 0941" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0033721 CG13159 - http://flybase.org/reports/FBgn0033721 protein_coding_gene - - - "BcDNA:RE25177, CG13159" - CG13159 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible" mesothoracic tergum DRSC06283 EK -0.60517028 -0.955956894 1.636995156 0.130856873 2.159841255 0.55996082 FBgn0051131 CG31131 - http://flybase.org/reports/FBgn0051131 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG31131 - CG31131 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0043559 Su(ro[DOM])1480 Su(ro[DOM])1480 http://flybase.org/reports/FBgn0043559 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with ro cellular_component ; GO:0005575 | no biological data available Su(ro[DOM])1480 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0063598 CS3-1 "Calcineurin suppressor, chromosome 3, group 1" http://flybase.org/reports/FBgn0063598 gene - - - CS3-1 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0050203 CG30203 - http://flybase.org/reports/FBgn0050203 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 - - "CT39323, CG17740, CG30203" "IPR000884:Thrombospondin type-1 (TSP1) repeat, IPR002223:Pancreatic trypsin inhibitor Kunitz domain, IPR002861:Reeler domain, IPR009465:Spondin, N-terminal" CG30203 27-Aug-18 DroID_v2018_08 "Drer\spon1b, Drer\thsd7aa, Drer\spon1a, Drer\thsd7bb, Drer\thsd7ba" - Cele\spon-1 "Xtro\thsd7b, Xtro\spon1, Xtro\thsd7a" "Mmus\Spon1, Mmus\Thsd7b, Mmus\Thsd7a" "Hsap\SPON1, Hsap\THSD7A, Hsap\THSD7B" viable DRSC06690 K -0.252730836 -0.12889358 0.101228917 0.287352377 2.769842121 1.284844502 FBgn0260049 flr flare http://flybase.org/reports/FBgn0260049 protein_coding_gene actin binding ; GO:0003779 | inferred from sequence or structural similarity with NCBI_gi:1168395 actin filament binding ; GO:0051015 | inferred from biological aspect of ancestor with PANTHER:PTN000458108 "regulation of actin filament polymerization ; GO:0030833 | inferred from mutant phenotype actin filament depolymerization ; GO:0030042 | inferred from mutant phenotype regulation of actin filament depolymerization ; GO:0030834 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype positive regulation of actin filament depolymerization ; GO:0030836 | inferred from biological aspect of ancestor with PANTHER:PTN000458108 sarcomere organization ; GO:0045214 | inferred from mutant phenotype negative regulation of Arp2/3 complex-mediated actin nucleation ; GO:0034316 | inferred from genetic interaction with GMF, Arpc5 imaginal disc-derived wing hair organization ; GO:0035317 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype establishment of planar polarity ; GO:0001736 | inferred from mutant phenotype" "actomyosin, actin portion ; GO:0042643 | inferred from biological aspect of ancestor with PANTHER:PTN000458108 cytoskeleton ; GO:0005856 | inferred from direct assay cortical actin cytoskeleton ; GO:0030864 | inferred from biological aspect of ancestor with PANTHER:PTN000458108" "CG10724, flr, AIP1, Aip1, aip1" "IPR017986:WD40-repeat-containing domain, IPR001680:WD40 repeat, IPR015943:WD40/YVTN repeat-like-containing domain" CG10724 27-Aug-18 DroID_v2018_08 "Drer\LOC108179016, Drer\wdr1" Scer\AIP1 "Cele\aipl-1, Cele\unc-78, Cele\wdr-48" Xtro\wdr1 Mmus\Wdr1 Hsap\WDR1 FBgn0041337 Cyp309a2 Cyp309a2 http://flybase.org/reports/FBgn0041337 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN001209891" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "309a2, CG18559, Cyp309a2" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG18559 27-Aug-18 DroID_v2018_08 "Drer\cyp3c3, Drer\tbxas1, Drer\cyp3c1, Drer\cyp3c4, Drer\cyp3c2, Drer\cyp3a65" "Scer\DIT2, Scer\ERG11" "Cele\cyp-13A11, Cele\cyp-13A10, Cele\cyp-13A12, Cele\cyp-25A1, Cele\cyp-13A4, Cele\cyp-13A8, Cele\cyp-13A3, Cele\cyp-13A2, Cele\cyp-13A1, Cele\cyp-44A1, Cele\cyp-13A6, Cele\cyp-25A2, Cele\cyp-25A3, Cele\cyp-43A1, Cele\cyp-13A7, Cele\cyp-13A5, Cele\cyp-25A4, Cele\cyp-13B1, Cele\cyp-13B2, Cele\cyp-25A6" "Xtro\tbxas1, Xtro\cyp3a5, Xtro\LOC100494419, Xtro\cyp3a4" "Mmus\Cyp3a59, Mmus\Cyp3a16, Mmus\Cyp3a41a, Mmus\Tbxas1, Mmus\Cyp3a25, Mmus\Cyp3a57, Mmus\Cyp3a41b, Mmus\Cyp3a11, Mmus\Cyp3a13, Mmus\Cyp3a44" "Hsap\CYP3A4, Hsap\CYP3A5, Hsap\CYP3A7, Hsap\CYP3A43, Hsap\TBXAS1, Hsap\CYP3A7-CYP3A51P" viable FBgn0024643 l(2)k11326 lethal (2) k11326 http://flybase.org/reports/FBgn0024643 - gene - - - "113/26, l(2)k11326" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" imaginal disc FBgn0002562 Lsp1alpha Larval serum protein 1 alpha http://flybase.org/reports/FBgn0002562 - protein_coding_gene - - lipid particle ; GO:0005811 | inferred from direct assay larval serum protein complex ; GO:0005616 | inferred from direct assay "Lsp1, Lsp1-alpha, LSP-1, Lsp1alpha, CG2559, DmeLSP1a, LSP-1alpha, LSP 1, Lsp-1alpha, LSP1alpha, LSP1-alpha, LSP-1 alpha, LSP1, LSP1ALPHA" "IPR000896:Hemocyanin/hexamerin middle domain, IPR005203:Hemocyanin, C-terminal, IPR005204:Hemocyanin, N-terminal, IPR008922:Uncharacterised domain, di-copper centre, IPR013788:Hemocyanin/hexamerin, IPR014756:Immunoglobulin E-set" CG2559 27-Aug-18 DroID_v2018_08 - - - - - - " larval stage | second instar -- larval stage | third instar , larval stage | third instar " embryonic/larval fat body

"electrophoretic variant,viable,fertile" egg DRSC25329 K 0.252334637 -0.125277535 -0.230797314 0.298288006 0.166907384 -2.559554076 FBgn0039027 CG7031 - http://flybase.org/reports/FBgn0039027 protein_coding_gene - - - CG7031 IPR011989:Armadillo-like helical CG7031 27-Aug-18 DroID_v2018_08 - - Cele\T26C11.2 - Mmus\Ggn "Hsap\GGN, Hsap\TPRX1" viable DRSC23028 K 1.844139299 1.48416253 FBgn0030936 CG6481 - http://flybase.org/reports/FBgn0030936 protein_coding_gene - - - CG6481 - CG6481 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0040368 eIF4E7 eukaryotic translation initiation factor 4E7 http://flybase.org/reports/FBgn0040368 protein_coding_gene RNA 7-methylguanosine cap binding ; GO:0000340 | inferred from direct assay translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity translation initiation factor activity ; GO:0003743 | inferred from genetic interaction with SGD:S000005499 RNA cap binding ; GO:0000339 | inferred from sequence or structural similarity eukaryotic initiation factor 4G binding ; GO:0031370 | inferred from physical interaction with eIF4G1 protein binding ; GO:0005515 | inferred from physical interaction with Thor translational initiation ; GO:0006413 | inferred from genetic interaction with SGD:S000005499 eukaryotic translation initiation factor 4F complex ; GO:0016281 | inferred from physical interaction with eIF4G1 eukaryotic translation initiation factor 4F complex ; GO:0016281 | inferred from sequence or structural similarity "CG32859, EG:BACR42I17.1, CT31794, CG11393, CG11392, eIF4E, eIF4E7, eIF4E-7" "IPR001040:Translation Initiation factor eIF- 4e, IPR023398:Translation Initiation factor eIF- 4e-like, IPR019770:Eukaryotic translation initiation factor 4E (eIF-4E), conserved site" CG32859 27-Aug-18 DroID_v2018_08 "Drer\eif4eb, Drer\eif4ea, Drer\eif4e1b, Drer\sesn2, Drer\si:zfos-80g12.1, Drer\sesn1, Drer\eif4e1c" Scer\CDC33 "Cele\ife-5, Cele\ife-1, Cele\ife-3, Cele\ife-2" "Xtro\sesn1, Xtro\sesn3, Xtro\eif4e, Xtro\eif4e1b" "Mmus\Sesn2, Mmus\Sesn1, Mmus\Eif4e, Mmus\Sesn3, Mmus\Eif4e1b" "Hsap\SESN2, Hsap\SESN3, Hsap\SESN1, Hsap\EIF4E, Hsap\EIF4E1B" "viable,partially lethal - majority die,some die during pupal stage" FBgn0263770 CR43687 - http://flybase.org/reports/FBgn0263770 pseudogene_attribute - - - CR43687 - CR43687 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065445 l(2)SH1426 lethal (2) SH1426 http://flybase.org/reports/FBgn0065445 gene - - - "l(2)SH1426, l(2)SH2 1426" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0014927 anon-72ABk anon-72ABk http://flybase.org/reports/FBgn0014927 - gene - - - anon-72ABk - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266052 lncRNA:CR44817 - http://flybase.org/reports/FBgn0266052 non_protein_coding_gene - - - CR44817 - CR44817 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0014881 Ssb-c15a Single stranded-binding protein c15a http://flybase.org/reports/FBgn0014881 - gene - - - "c15a, Ssb-c15a" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265911 lncRNA:CR44700 - http://flybase.org/reports/FBgn0265911 non_protein_coding_gene - - - CR44700 - CR44700 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0070039 3R-64-22 3R-64-22 http://flybase.org/reports/FBgn0070039 gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available 3R-64-22 - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage" FBgn0265308 lncRNA:CR44281 - http://flybase.org/reports/FBgn0265308 non_protein_coding_gene - - - CR44281 - CR44281 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264899 CG44090 - http://flybase.org/reports/FBgn0264899 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44090 - CG44090 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030913 CG6123 - http://flybase.org/reports/FBgn0030913 protein_coding_gene - - - CG6123 - CG6123 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC30011 K 0.444283181 0.274089522 -0.061174379 0.575082419 1.316855014 1.906566258 FBgn0267015 lncRNA:CR45459 - http://flybase.org/reports/FBgn0267015 non_protein_coding_gene - - - CR45459 - CR45459 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000318 cl clot http://flybase.org/reports/FBgn0000318 "FBgn0031709, FBgn0063070" protein_coding_gene protein-disulfide reductase activity ; GO:0047134 | inferred from biological aspect of ancestor with PANTHER:PTN000278790 eye pigment biosynthetic process ; GO:0006726 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000278790 "CG11024, BcDNA:RE06767, cl" "IPR010357:Protein of unknown function DUF953, thioredoxin-like, IPR012336:Thioredoxin-like fold" CG11024 27-Aug-18 DroID_v2018_08 Drer\txndc17 - Cele\Y71H2AR.1 Xtro\txndc17 Mmus\Txndc17 Hsap\TXNDC17 "viable,fertile,eye color defective" "Malpighian tubule,pigment cell" FBgn0267920 CR46201 - http://flybase.org/reports/FBgn0267920 non_protein_coding_gene - - - "CR46201, lincRNA.919" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262118 l(2)NC173 - http://flybase.org/reports/FBgn0262118 gene - - - l(2)NC173 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031281 Saf6 SAGA factor-like TAF6 http://flybase.org/reports/FBgn0031281 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with e(y)1 inferred from physical interaction with e(y)1 positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay SAGA complex ; GO:0000124 | inferred from direct assay SAGA-type complex ; GO:0070461 | inferred from direct assay "SAF6, saf6, Saf6, CG3883" - CG3883 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" DRSC00633 E -0.149480242 0.362396254 -0.241661292 1.692060646 -0.448121921 0.217145176 FBgn0023433 l(2)4-3A lethal (2) 4-3A http://flybase.org/reports/FBgn0023433 - gene - - - l(2)4-3A - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0019845 anon-XXIII anon-XXIII http://flybase.org/reports/FBgn0019845 - gene - - - "XXIII, anon-XXIII" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005284 M(3)S36 Minute (3) 36 http://flybase.org/reports/FBgn0005284 - gene - - - "M(3)s36, M(3)S36" - - 27-Aug-18 DroID_v2018_08 - - - - - - "Minute,dominant,visible" macrochaeta FBgn0069447 E(br)333 E(br)333 http://flybase.org/reports/FBgn0069447 gene - - - E(br)333 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,visible,semidominant" leg FBgn0044411 Scim16 Sensitized chromosome inheritance modifier 16 http://flybase.org/reports/FBgn0044411 gene - female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype - Scim16 - - 27-Aug-18 DroID_v2018_08 - - - - - - "meiotic cell cycle defective,dominant" FBgn0011195 l(1)302-9 lethal (1) 302-9 http://flybase.org/reports/FBgn0011195 FBgn0010202 gene - - - "302-9, l(1)302-9" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0053964 CG33964 - http://flybase.org/reports/FBgn0053964 protein_coding_gene - - - "CG8447, CG33154, CG13174, CG33964, CT32415" "IPR025714:Methyltransferase domain, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG33964 27-Aug-18 DroID_v2018_08 "Drer\mettl25, Drer\orc3, Drer\rrnad1" - Cele\F25H2.12 "Xtro\rrnad1, Xtro\orc3, Xtro\mettl25" "Mmus\Mettl25, Mmus\Rrnad1, Mmus\Orc3" "Hsap\ORC3, Hsap\RRNAD1, Hsap\METTL25" FBgn0046123 E(To)12 E(To)12 http://flybase.org/reports/FBgn0046123 gene - - - E(To)12 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0037638 CG8379 - http://flybase.org/reports/FBgn0037638 protein_coding_gene - - - "anon-WO0118547.250, CG8379" "IPR013636:Domain of unknown function DUF1741, IPR011989:Armadillo-like helical" CG8379 27-Aug-18 DroID_v2018_08 Drer\zgc:63733 - - Xtro\c10orf76 Mmus\9130011E15Rik Hsap\C10orf76 "viable,fertile" FBgn0267432 kl-3 male fertility factor kl3 http://flybase.org/reports/FBgn0267432 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011704 ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity with CG9492 traceable author statement ATP-dependent microtubule motor activity, minus-end-directed ; GO:0008569 | inferred from sequence or structural similarity with UniProtKB:A8JDH8" cilium movement ; GO:0003341 | inferred from sequence or structural similarity with UniProtKB:A8JDH8 microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity outer dynein arm ; GO:0036157 | inferred from sequence or structural similarity with UniProtKB:Q8TE73 axonemal dynein complex ; GO:0005858 | inferred from sequence or structural similarity axonemal dynein complex ; GO:0005858 | inferred from mutant phenotype "CG17629, kl3, kl-3, CG45785, CG40992, CG40936, kl-4, Y104b, Lms3, CG40443, ms(Y)104b, DHC4A" "IPR026983:Dynein heavy chain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR013594:Dynein heavy chain, domain-1, IPR004273:Dynein heavy chain domain, IPR011704:ATPase, dynein-related, AAA domain, IPR013602:Dynein heavy chain, domain-2, IPR003593:AAA+ ATPase domain, IPR024317:Dynein heavy chain, P-loop containing D4 domain, IPR024743:Dynein heavy chain, coiled coil stalk" CG45785 27-Aug-18 DroID_v2018_08 "Drer\dnah5, Drer\si:dkeyp-87a6.1" - - - "Mmus\Dnah5, Mmus\Dnah8" "Hsap\DNAH5, Hsap\DNAH8" FBgn0264277 Su(Mir)3 - http://flybase.org/reports/FBgn0264277 gene - - - Su(Mir)3 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0062572 Mod(var)E1350 Mod(var)E1350 http://flybase.org/reports/FBgn0062572 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "E1350, Mod(var)E1350" - - 27-Aug-18 DroID_v2018_08 - - - - - - "enhancer of variegation,non-enhancer of variegation,non-suppressor of variegation,viable" FBgn0041827 ISO-Q ISO-Q http://flybase.org/reports/FBgn0041827 gene - - - ISO-Q - - 27-Aug-18 DroID_v2018_08 - - - - - - "flightless,recessive" FBgn0028146 l(3)S045507b lethal (3) S045507b http://flybase.org/reports/FBgn0028146 gene - - - "0455/07, l(3)S045507, l(3)S045507b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0060363 l(3)S138613a lethal (3) S138613a http://flybase.org/reports/FBgn0060363 gene - - - "1386/13, l(3)S138613a" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0022772 Orc1 Origin recognition complex subunit 1 http://flybase.org/reports/FBgn0022772 - protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959 chromatin binding ; GO:0003682 | inferred from electronic annotation with InterPro:IPR001025 DNA endoreduplication ; GO:0042023 | NOT inferred from mutant phenotype DNA amplification ; GO:0006277 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype cell proliferation ; GO:0008283 | inferred from mutant phenotype DNA replication initiation ; GO:0006270 | inferred from direct assay nuclear origin of replication recognition complex ; GO:0005664 | inferred from direct assay "ORC, rDmORC, DmORC1, ORC1, dORC1, CG10667, Orc1, DmOrc1p, orc1, DmOrc1" "IPR001025:Bromo adjacent homology (BAH) domain, IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR015163:Cdc6, C-terminal, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG10667 27-Aug-18 DroID_v2018_08 "Drer\cdc6, Drer\orc1" "Scer\CDC6, Scer\ORC1, Scer\SIR3" "Cele\cdc-6, Cele\orc-1" Xtro\orc1 "Mmus\Cdc6, Mmus\Orc1" "Hsap\CDC6, Hsap\ORC1" embryonic stage && larval stage "lethal,polyphasic,female sterile,male sterile,visible,neuroanatomy defective,viable" "eye,ommatidium,interommatidial bristle,eye-antennal disc,posterior,morphogenetic furrow,stage S10B oocyte,follicle cell & nucleus,egg,chorion,dorsal appendage,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" DRSC07496 K -1.173812525 -0.393555002 -0.644168193 -1.49636062 0.220241507 1.822720547 FBgn0082339 HM617 HM617 http://flybase.org/reports/FBgn0082339 gene - - - HM617 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0082980 snoRNA:Psi28S-2996 snoRNA:Psi28S-2996 http://flybase.org/reports/FBgn0082980 snoRNA_gene - - - "snoRNA:Psi28S-2996, psi28s-2996, Psi 28S-2996, snoRNA:RpL5-a" - CR43565 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0084040 CG41480 - http://flybase.org/reports/FBgn0084040 protein_coding_gene - - - CG41480 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0014287 l(3)64Af lethal (3) 64Af http://flybase.org/reports/FBgn0014287 - gene - - - l(3)64Af - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004564 l(3)63Bh lethal (3) 63Bh http://flybase.org/reports/FBgn0004564 - gene - - - l(3)63Bh - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0065312 l(2)SH1938 lethal (2) SH1938 http://flybase.org/reports/FBgn0065312 gene - - - "l(2)SH1938, l(2)SH2 1938" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0035384 CG2113 - http://flybase.org/reports/FBgn0035384 protein_coding_gene actin binding ; GO:0003779 | inferred from sequence or structural similarity with MGI:MGI:2444891 "positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from sequence or structural similarity with MGI:MGI:2444891" actin cytoskeleton ; GO:0015629 | inferred from sequence or structural similarity with MGI:MGI:2444891 "BcDNA:AT18037, CG2113" IPR027817:Costars domain CG2113 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-29b11.3, Drer\abraa, Drer\abrab, Drer\abracl" - "Cele\clec-119, Cele\clec-73, Cele\clec-117, Cele\clec-151, Cele\clec-153, Cele\tag-243, Cele\F36F2.1, Cele\clec-123, Cele\clec-175, Cele\clec-79" Xtro\abra "Mmus\Abracl, Mmus\Abra" "Hsap\ABRA, Hsap\ABRACL" FBgn0267660 lncRNA:CR45998 - http://flybase.org/reports/FBgn0267660 non_protein_coding_gene - - - CR45998 - CR45998 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265889 lncRNA:CR44678 - http://flybase.org/reports/FBgn0265889 non_protein_coding_gene - - - CR44678 - CR44678 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0066314 Aexon.s Aexon.s http://flybase.org/reports/FBgn0066314 gene - - - Aexon.s - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0015372 RabX1 RabX1 http://flybase.org/reports/FBgn0015372 FBgn0034872 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579, InterPro:IPR005225 GTPase activity ; GO:0003924 | traceable author statement GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11" vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype synapse ; GO:0045202 | inferred from direct assay recycling endosome ; GO:0055037 | inferred from direct assay vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 "AAF47018, DmRabX1, l(2)k06908, chr, CG3870, RabX1, rabX1, chrw, RAB5c, Chrw" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG3870 27-Aug-18 DroID_v2018_08 "Drer\rab31, Drer\rab5ab, Drer\rab20, Drer\rab5b, Drer\rab5aa, Drer\rab24, Drer\rab22a, Drer\rab5c, Drer\zgc:154045" "Scer\YPT53, Scer\YPT52, Scer\VPS21, Scer\YPT10" "Cele\rab-5, Cele\C56E6.2, Cele\rab-21" "Xtro\rab5c, Xtro\rab20, Xtro\rab24, Xtro\rab5b, Xtro\rab21, Xtro\mras, Xtro\rab5a, Xtro\rab22a" "Mmus\Rab20, Mmus\Rab31, Mmus\Rab24, Mmus\Rab32, Mmus\Rab21, Mmus\Rab17, Mmus\Rab22a, Mmus\Rab5c, Mmus\Rab5a, Mmus\Rab5b" "Hsap\RAB20, Hsap\RAB31, Hsap\RAB5C, Hsap\RAB22A, Hsap\RAB32, Hsap\RAB21, Hsap\RAB5A, Hsap\RAB24, Hsap\RAB5B, Hsap\RAB17" "lethal,recessive" "chordotonal organ,lateral,ventral,external sensory organ,multidendritic neuron" FBgn0060635 l(3)S084512b lethal (3) S084512b http://flybase.org/reports/FBgn0060635 gene - - - "0845/12, l(3)S084512b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of prepupal stage,recessive,some die during prepupal stage" FBgn0036931 CG14183 - http://flybase.org/reports/FBgn0036931 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959 - - CG14183 "IPR000048:IQ motif, EF-hand binding site, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR003959:ATPase, AAA-type, core" CG14183 27-Aug-18 DroID_v2018_08 "Drer\fign, Drer\iqca1, Drer\fignl1, Drer\spast, Drer\si:dkey-157g16.6, Drer\zgc:153738" "Scer\YTA6, Scer\SAP1" - "Xtro\fignl1, Xtro\fign, Xtro\spast" "Mmus\Fignl1, Mmus\Fignl2, Mmus\Spast, Mmus\Iqca, Mmus\Fign, Mmus\4931409K22Rik" "Hsap\SPAST, Hsap\FIGNL1, Hsap\IQCA1, Hsap\FIGN, Hsap\IQCA1L" viable FBgn0011216 disd dispersed at 46C http://flybase.org/reports/FBgn0011216 - gene - spermatid development ; GO:0007286 | inferred from mutant phenotype - disd - - 27-Aug-18 DroID_v2018_08 - - - - - - male semi-sterile spermatid & nucleus FBgn0035725 Mis12 Mis12 http://flybase.org/reports/FBgn0035725 protein_coding_gene - chromosome segregation ; GO:0007059 | inferred from mutant phenotype mitotic metaphase plate congression ; GO:0007080 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype mitotic chromosome movement towards spindle pole ; GO:0007079 | inferred from mutant phenotype "kinetochore ; GO:0000776 | inferred from direct assay chromosome, centromeric region ; GO:0000775 | inferred from direct assay kinetochore ; GO:0000776 | colocalizes_with inferred from direct assay Ndc80 complex ; GO:0031262 | inferred from direct assay" "BcDNA:RE19545, CG18156, dmMis12, Mis12, Mis-12" - CG18156 27-Aug-18 DroID_v2018_08 Drer\mis12 - - Xtro\mis12 - Hsap\MIS12 "mitotic cell cycle defective,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "condensed nuclear chromosome,metaphase,nucleus,spindle,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0085799 CR41544 - http://flybase.org/reports/FBgn0085799 rRNA_gene - - - CR41544 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032910 CG9265 - http://flybase.org/reports/FBgn0032910 protein_coding_gene - - - CG9265 "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain" CG9265 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-221h15.4, Drer\rdh20, Drer\sdr16c5a, Drer\sdr16c5b, Drer\rdh10b, Drer\dhrs3a, Drer\rdh10a, Drer\dhrs3b" "Scer\YDL114W, Scer\TDA5" "Cele\dhs-29, Cele\dhs-3, Cele\dhs-19, Cele\dhs-4" "Xtro\hsd17b11, Xtro\hsd17b13, Xtro\rdh10, Xtro\sdr16c5, Xtro\dhrs3" "Mmus\Sdr16c6, Mmus\Hsd17b13, Mmus\Sdr16c5, Mmus\Hsd17b11, Mmus\Dhrs3, Mmus\Rdh10" "Hsap\HSD17B13, Hsap\RDH10, Hsap\HSD17B11, Hsap\SDR16C5, Hsap\DHRS3" "viable,fertile" DRSC03178 E -0.925043617 -0.454212092 -1.792542037 0.463251428 -0.050592619 -0.829007981 FBgn0023056 l(1)2Fg lethal (1) 2Fg http://flybase.org/reports/FBgn0023056 - gene - - - "B2/27.14, AS2/11, l(1)2Fg" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0011889 tRNA:Lys-CTT-1-2 transfer RNA:Lysine-CTT 1-2 http://flybase.org/reports/FBgn0011889 "FBgn0003795, FBgn0011886, FBgn0050310, FBgn0050517, FBgn0060186" tRNA_gene AAG codon-amino acid adaptor activity ; GO:0033444 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033444 cytosol ; GO:0005829 | inferred by curator from GO:0033444 "35SLys, tRNA[Lys][[2]], AE002769.trna5-LysCTT, tRNA:K2, tRNA:K:CTT:AE002769-c, tRNA:lys2:42Ac, CR30310, CR30517, tRNAlys, chr2R.trna96-LysCTT, tRNA-Lys-CTT-1-2, tRNA:Lys-CTT-1-2, tRNA:K2:42Ac, AAG" - CR30517 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266439 CG45069 - http://flybase.org/reports/FBgn0266439 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG45069, CG3419" - CG45069 27-Aug-18 DroID_v2018_08 - Scer\SMP3 - - Mmus\Pigz Hsap\PIGZ viable FBgn0044104 E(rst)C421 E(rst)C421 http://flybase.org/reports/FBgn0044104 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "C421, E(rst)C421" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0015819 Su(Kr[If]) Suppressor of Kruppel-Irregular facets http://flybase.org/reports/FBgn0015819 - gene - - - Su(Kr[If]) - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000594 Est-P Esterase P http://flybase.org/reports/FBgn0000594 FBgn0017620 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from direct assay - - "EST7, Est-7, PsiEst-6, EST-5, Est-5, ESTP, EstP, est-P, yEst-6, CG17148, Est-P, yEst6, psiEst-6, Est7" "IPR002018:Carboxylesterase, type B, IPR019819:Carboxylesterase type B, conserved site, IPR019826:Carboxylesterase type B, active site, IPR029058:Alpha/Beta hydrolase fold" CG17148 27-Aug-18 DroID_v2018_08 "Drer\ces2, Drer\nlgn3b, Drer\cell, Drer\nlgn1, Drer\nlgn3a, Drer\ces3, Drer\nlgn2b, Drer\nlgn4b, Drer\nlgn4a, Drer\si:ch211-93f2.1, Drer\cel.1, Drer\nlgn2a" - "Cele\K07C11.4, Cele\K11G9.1, Cele\T28C12.5, Cele\F15A8.6, Cele\F56C11.6, Cele\T07H6.1, Cele\ges-1, Cele\R173.3, Cele\F13H6.3, Cele\F07C4.12, Cele\Y71H2AM.13, Cele\T28C12.4, Cele\C52A10.2, Cele\B0238.1, Cele\K11G9.2, Cele\K11G9.3, Cele\C52A10.1" "Xtro\nlgn4x, Xtro\LOC100494782, Xtro\cel, Xtro\nlgn3, Xtro\nlgn2, Xtro\ces2, Xtro\ces3" "Mmus\Ces2h, Mmus\Ces2g, Mmus\Nlgn1, Mmus\Cel, Mmus\Ces1f, Mmus\Ces3b, Mmus\Ces2c, Mmus\Ces5a, Mmus\Nlgn3, Mmus\Ces1h, Mmus\Ces4a, Mmus\Ces3a, Mmus\Ces1c, Mmus\Ces2e, Mmus\Ces1d, Mmus\Ces1g, Mmus\Ces2b, Mmus\Nlgn2, Mmus\Ces2a, Mmus\Ces1b, Mmus\Ces1e, Mmus\Ces2f" "Hsap\CES4A, Hsap\CES3, Hsap\CES2, Hsap\CES5A, Hsap\NLGN4Y, Hsap\CES1, Hsap\NLGN2, Hsap\NLGN1, Hsap\NLGN4X, Hsap\NLGN3, Hsap\CEL" " larval stage | late , adult stage " "electrophoretic variant,slow,fast,viable,partially lethal - majority die" FBgn0063378 snoRNA:U31:54Ed snoRNA:U31:54Ed http://flybase.org/reports/FBgn0063378 snoRNA_gene - - - "U31snoRNA, CR32899, snoRNA:U31:54Ed" - CR32899 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031897 CG13784 - http://flybase.org/reports/FBgn0031897 protein_coding_gene - - - "BcDNA:SD10385, CG13784" IPR006603:PQ-loop repeat CG13784 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-246g23.2, Drer\pqlc1, Drer\pqlc2" "Scer\YPQ1, Scer\RTC2, Scer\YDR090C, Scer\YMR010W, Scer\YPQ2" Cele\T19A6.1 "Xtro\pqlc1.1, Xtro\LOC733474, Xtro\pqlc1.2, Xtro\MGC69309" "Mmus\Pqlc1, Mmus\Pqlc2" "Hsap\PQLC2L, Hsap\PQLC2, Hsap\PQLC1" viable FBgn0086474 l(3)d05983 - http://flybase.org/reports/FBgn0086474 gene - - - l(3)d05983 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0024856 l(3)96Bf lethal (3) 96Bf http://flybase.org/reports/FBgn0024856 - gene - - - l(3)96Bf - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0053160 CG33160 - http://flybase.org/reports/FBgn0053160 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - "SP183, CG11531, CG33160" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG33160 27-Aug-18 DroID_v2018_08 "Drer\habp2, Drer\plat, Drer\tmprss4a" - Cele\try-1 - "Mmus\Tmprss4, Mmus\Plat, Mmus\Prss58, Mmus\Gzmk, Mmus\Habp2" "Hsap\HABP2, Hsap\TMPRSS4, Hsap\GZMK, Hsap\PLAT" viable FBgn0037202 Ssl1 Suppressor of stem-loop mutation http://flybase.org/reports/FBgn0037202 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR004595 transcription factor activity, core RNA polymerase binding ; GO:0000990 | contributes_to inferred by curator from GO:0005675 nucleic acid binding ; GO:0003676 | inferred from biological aspect of ancestor with PANTHER:PTN000294370" transcriptional open complex formation at RNA polymerase II promoter ; GO:0001113 | inferred from sequence or structural similarity with HGNC:4656 nucleotide-excision repair ; GO:0006289 | inferred from sequence or structural similarity with HGNC:4656 transcription from RNA polymerase II promoter ; GO:0006366 | inferred from direct assay transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:4656 inferred from sequence or structural similarity with SGD:S000003995 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN000294370 nucleotide-excision repair ; GO:0006289 | inferred from biological aspect of ancestor with PANTHER:PTN000294370 promoter clearance from RNA polymerase II promoter ; GO:0001111 | inferred from sequence or structural similarity with HGNC:4656 holo TFIIH complex ; GO:0005675 | inferred from direct assay core TFIIH complex ; GO:0000439 | inferred from sequence or structural similarity with HGNC:4656 inferred from sequence or structural similarity with SGD:S000003995 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:4656 holo TFIIH complex ; GO:0005675 | inferred from sequence or structural similarity with HGNC:4656 inferred from sequence or structural similarity with SGD:S000003995 "SSL1, CG11115, Ssl1, p44, ssl1" "IPR002035:von Willebrand factor, type A, IPR004595:TFIIH C1-like domain, IPR012170:TFIIH subunit Ssl1/p44, IPR013087:Zinc finger C2H2-type, IPR007198:Ssl1-like" CG11115 27-Aug-18 DroID_v2018_08 Drer\gtf2h2 Scer\SSL1 Cele\T16H12.4 Xtro\gtf2h2 Mmus\Gtf2h2 "Hsap\GTF2H2C_2, Hsap\GTF2H2C, Hsap\GTF2H2" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0262290 mir-iab-8 mir-iab-8 stem loop http://flybase.org/reports/FBgn0262290 miRNA_gene - - - "miR-iab-8, mir-iab-4as-5p, miR-iab-4as, dme-mir-iab-8, iab-8, miR-iab-4AS, mir-iab-4as, mir-iab-8, mir-iab8, miR-iab-8-5p, CR42997, MIR-iab-4as, iab-8 miRNA, dme-iab-8, dme-miR-iab-8, MiR-iab8, miR-iab8-3p, miR-iab8-5p" - CR42997 27-Aug-18 DroID_v2018_08 - - - - - - "visible,homeotic,viable,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of pupal stage,some die during pupal stage,lethal" "wing,ectopic,haltere" FBgn0000814 fs(1)K254 female sterile (1) K254 http://flybase.org/reports/FBgn0000814 - gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | traceable author statement cellular_component ; GO:0005575 | no biological data available fs(1)K254 - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile soma-dependent,female sterile,recessive,lethal - all die before end of pupal stage,heat sensitive,some die during pupal stage" "dorsal appendage,chorion" FBgn0053766 CG33766 - http://flybase.org/reports/FBgn0053766 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG14458, CG33766" IPR010512:Protein of unknown function DUF1091 CG33766 27-Aug-18 DroID_v2018_08 - - - - - - DRSC11717 E 0.911471654 -0.036711042 2.562516219 0.920692551 -0.005139367 0.971594994 FBgn0267641 lncRNA:CR45979 - http://flybase.org/reports/FBgn0267641 non_protein_coding_gene - - - CR45979 - CR45979 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260494 boa baobab http://flybase.org/reports/FBgn0260494 gene - axonogenesis ; GO:0007409 | inferred from mutant phenotype - boa - - 27-Aug-18 DroID_v2018_08 - - - - - - neuroanatomy defective "dendritic arborizing neuron,axon" FBgn0004072 fs(2)mel6 female sterile (2) maternal effect lethal 6 http://flybase.org/reports/FBgn0004072 - gene - - - "Mel 6, fs(2)mel6" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,semidominant,some die during embryonic stage" "cephalopharyngeal skeleton,maternal effect,embryonic head" FBgn0052269 CG32269 - http://flybase.org/reports/FBgn0052269 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "SP124, CG33161, CG11530, CG32269" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG32269 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-21e2.7, Drer\si:dkey-78l4.10" - "Cele\svh-1, Cele\try-1" - "Mmus\Prss53, Mmus\Prss36, Mmus\Prss55" "Hsap\PRSS57, Hsap\PRSS36, Hsap\PRSS53" FBgn0044382 T:SS-ea Signal sequence of ea http://flybase.org/reports/FBgn0044382 engineered_tag - - - "T:SS-ea, T:ea" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0052734 CG32734 - http://flybase.org/reports/FBgn0052734 protein_coding_gene - - - CG32734 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0053404 5SrRNA:CR33404 5SrRNA:CR33404 http://flybase.org/reports/FBgn0053404 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33404, 5SrRNA:CR33404" - CR33404 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0083278 E(smoDN)2515 Enhancer of smoDN 2515 http://flybase.org/reports/FBgn0083278 gene - - - E(smoDN)2515 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267005 lncRNA:CR45449 - http://flybase.org/reports/FBgn0267005 non_protein_coding_gene - - - "CR45449, R5_2L:3854289..3854886" - CR45449 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065750 l(2)SH0498 lethal (2) SH0498 http://flybase.org/reports/FBgn0065750 gene - - - "l(2)SH0498, l(2)SH2 0498" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0027142 l(3)71EFa lethal (3) 71EFa http://flybase.org/reports/FBgn0027142 - gene - - - l(3)71EFa - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0031896 CG4502 - http://flybase.org/reports/FBgn0031896 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon-WO0118547.403, CG4502" "IPR000608:Ubiquitin-conjugating enzyme E2, IPR016135:Ubiquitin-conjugating enzyme/RWD-like" CG4502 27-Aug-18 DroID_v2018_08 "Drer\ube2q2, Drer\ube2ql1, Drer\ube2q1" Scer\CDC34 Cele\ubc-25 "Xtro\ube2q2, Xtro\ube2ql1" "Mmus\Ube2q1, Mmus\Ube2ql1, Mmus\Ube2q2" "Hsap\UBE2QL1, Hsap\UBE2Q2, Hsap\UBE2Q1" "viable,fertile,visible,body color defective,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0267956 lncRNA:CR46236 - http://flybase.org/reports/FBgn0267956 non_protein_coding_gene - - - "CR46236, lincRNA.901" - CR46236 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262395 mir-12 mir-12 stem loop http://flybase.org/reports/FBgn0262395 miRNA_gene - "gene silencing by miRNA ; GO:0035195 | inferred from direct assay positive regulation of nuclear-transcribed mRNA poly(A) tail shortening ; GO:0060213 | inferred from genetic interaction with Ge-1, me31B positive regulation of smoothened signaling pathway ; GO:0045880 | inferred from mutant phenotype" - "dme-mir-12, mir-12, miR-12, MIR-12, CR42932, miR12, Mir-12, CR33076, pri-miR-12, MiR-12, dme-miR-12, dme-miR-12-3p, miR-12/283/304" - CR42932 27-Aug-18 DroID_v2018_08 - - - - - - embryonic stage -- adult stage "visible,lethal,lethal - all die before end of larval stage,some die during larval stage" "wing,wing vein,wing margin" FBgn0069233 gl(2L)179-26 gl(2L)179-26 http://flybase.org/reports/FBgn0069233 gene molecular_function ; GO:0003674 | no biological data available "anterior/posterior axis specification, embryo ; GO:0008595 | inferred from mutant phenotype" cellular_component ; GO:0005575 | no biological data available gl(2L)179-26 - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage,maternal effect" "egg,germline clone,maternal effect,dorsal appendage,cephalopharyngeal skeleton" FBgn0040824 CG14169 - http://flybase.org/reports/FBgn0040824 protein_coding_gene - - - CG14169 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033566 CG18004 - http://flybase.org/reports/FBgn0033566 protein_coding_gene - DNA replication ; GO:0006260 | inferred from electronic annotation with InterPro:IPR026678 DNA repair ; GO:0006281 | inferred from electronic annotation with InterPro:IPR026678 Ino80 complex ; GO:0031011 | inferred from biological aspect of ancestor with PANTHER:PTN001094779 CG18004 IPR026678:INO80 complex subunit E CG18004 27-Aug-18 DroID_v2018_08 Drer\ino80e - - - Mmus\Ino80e Hsap\INO80E FBgn0037655 Kcmf1 Potassium channel modulatory factor 1 http://flybase.org/reports/FBgn0037655 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000433 - - "CG11984, KCMF1, Kcmf1" "IPR000433:Zinc finger, ZZ-type, IPR008598:Drought induced 19 protein type, zinc-binding domain" CG11984 27-Aug-18 DroID_v2018_08 Drer\kcmf1 - "Cele\trf-1, Cele\ZK652.6" Xtro\kcmf1 Mmus\Kcmf1 Hsap\KCMF1 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0017461 TfIIIB Transcription factor IIIB http://flybase.org/reports/FBgn0017461 - gene - transcription from RNA polymerase III promoter ; GO:0006383 | traceable author statement - "TFIIIB, IIIB, TfIIIB" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001642 l(1)dn22 lethal (1) discs normal 22 http://flybase.org/reports/FBgn0001642 - gene - - - "l(1)d.norm.-22, l(1)dn22" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0085287 CG34258 - http://flybase.org/reports/FBgn0085287 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34258 - CG34258 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0015337 anon-23EFa anon-23EFa http://flybase.org/reports/FBgn0015337 - gene - - - anon-23EFa - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004578 l(3)hem lethal (3) hematopoiesis missing http://flybase.org/reports/FBgn0004578 - gene - - - "l(3)hem, l-(3)hem" - - 27-Aug-18 DroID_v2018_08 - - - - - - "cytokinesis defective,recessive,lethal - all die before end of larval stage,some die during larval stage" "prohemocyte,plasmatocyte,crystal cell,embryonic/larval lymph gland,embryonic/larval optic lobe,neuroblast" FBgn0028093 l(3)S078514 lethal (3) S078514 http://flybase.org/reports/FBgn0028093 gene - - - "0785/14, l(3)S078514" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0084050 CR41470 - http://flybase.org/reports/FBgn0084050 non_protein_coding_gene - - - CR41470 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0017436 anon-28Cc anon-28Cc http://flybase.org/reports/FBgn0017436 - gene - - - anon-28Cc - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0015499 l(3)65CEc lethal (3) 65CEc http://flybase.org/reports/FBgn0015499 - gene - - - "XII, l(3)65CEc" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0065920 l(2)SH0155 lethal (2) SH0155 http://flybase.org/reports/FBgn0065920 gene - - - "l(2)SH0155, l(2)SH2 0155" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0267576 lncRNA:CR45916 - http://flybase.org/reports/FBgn0267576 non_protein_coding_gene - - - "CR45916, pri-mir-9a" - CR45916 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0015894 su(Ubx[bx-1]) su(Ubx[bx-1]) http://flybase.org/reports/FBgn0015894 - gene - - - "anon-85AB, su(Ubx[bx-1])" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051681 CG31681 - http://flybase.org/reports/FBgn0051681 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 CG31681 "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG31681 27-Aug-18 DroID_v2018_08 - - "Cele\rab-11.1, Cele\try-1" - "Mmus\4930519F16Rik, Mmus\Prss55, Mmus\Prss36, Mmus\Prss53, Mmus\Tmprss4" "Hsap\PRSS45, Hsap\TMPRSS4, Hsap\PRSS36, Hsap\PRSS53" viable FBgn0005744 l(1)TK236 lethal (1) TK236 http://flybase.org/reports/FBgn0005744 - gene - - - "l236, l(1)TK236" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" "eye,lamina" FBgn0259192 CG42296 - http://flybase.org/reports/FBgn0259192 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "CG42296, CG15378" IPR002557:Chitin binding domain CG42296 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible" trichogen cell DRSC00394 E -0.0177916 0.429054985 0.236141796 1.634882326 0.239216821 -0.30082429 FBgn0031463 G6P Glucose-6-Phosphatase http://flybase.org/reports/FBgn0031463 protein_coding_gene glucose-6-phosphatase activity ; GO:0004346 | inferred from biological aspect of ancestor with PANTHER:PTN000287473 glucose 6-phosphate metabolic process ; GO:0051156 | inferred from biological aspect of ancestor with PANTHER:PTN000287473 gluconeogenesis ; GO:0006094 | inferred from biological aspect of ancestor with PANTHER:PTN000287473 membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN000287473 "CG15400, G6pase, G6P" IPR000326:Phosphatidic acid phosphatase type 2/haloperoxidase CG15400 27-Aug-18 DroID_v2018_08 "Drer\g6pca.2, Drer\g6pca.1, Drer\g6pcb, Drer\g6pc3" - - "Xtro\g6pc, Xtro\g6pc2" "Mmus\G6pc3, Mmus\G6pc, Mmus\G6pc2" "Hsap\G6PC3, Hsap\G6PC, Hsap\G6PC2" viable FBgn0015997 l(3)100CDa lethal (3) 100CDa http://flybase.org/reports/FBgn0015997 - gene - - - l(3)100CDa - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0052247 CG32247 - http://flybase.org/reports/FBgn0052247 protein_coding_gene - - - CG32247 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038262 CG14857 - http://flybase.org/reports/FBgn0038262 protein_coding_gene organic anion transmembrane transporter activity ; GO:0008514 | inferred from biological aspect of ancestor with PANTHER:PTN001936837 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001175408 CG14857 "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG14857 27-Aug-18 DroID_v2018_08 "Drer\slc22a7b.1, Drer\zmp:0000001102, Drer\slc22a13, Drer\oatx, Drer\slc22a21, Drer\slc22a5, Drer\zgc:175176, Drer\slc22a7b.2, Drer\sv2, Drer\LOC100334012, Drer\LOC101884074, Drer\slc22a7b.3, Drer\slc22a6l" "Scer\FLR1, Scer\HXT9, Scer\AQR1, Scer\QDR1, Scer\DTR1, Scer\YHK8, Scer\PHO84, Scer\TPO3, Scer\QDR3, Scer\TPO1, Scer\HXT2, Scer\TPO2, Scer\GIT1, Scer\QDR2" "Cele\C53B4.1, Cele\C06H5.6, Cele\ZK892.3, Cele\B0252.3, Cele\oct-1, Cele\Y66D12A.13, Cele\Y51A2D.18, Cele\C46C2.2, Cele\T22F7.1, Cele\B0361.11, Cele\Y57G11C.23" Xtro\slc22a6 "Mmus\Slc22a7, Mmus\Slc22a20, Mmus\Slc22a6, Mmus\Slc22a8, Mmus\Svop, Mmus\Slc22a2, Mmus\Slc22a14, Mmus\Slc22a26, Mmus\Slc22a4, Mmus\Slc22a5, Mmus\Slc22a29, Mmus\Slc22a28, Mmus\Slc22a21, Mmus\Slc22a22, Mmus\Sv2c, Mmus\Slc22a23, Mmus\Slc22a16, Mmus\Slc22a19, Mmus\Slc22a27, Mmus\Slc22a30" "Hsap\SLC22A8, Hsap\SLC22A10, Hsap\SVOP, Hsap\SLC22A1, Hsap\SLC22A5, Hsap\SLC22A24, Hsap\SLC22A11, Hsap\SLC22A4, Hsap\SLC22A7, Hsap\SLC22A12, Hsap\SV2C, Hsap\SLC22A2, Hsap\SLC22A9, Hsap\SLC22A25, Hsap\SLC22A23, Hsap\SLC22A6, Hsap\SV2B" FBgn0267987 lncRNA:CR46254 - http://flybase.org/reports/FBgn0267987 non_protein_coding_gene - - - CR46254 - CR46254 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0261503 lncRNA:CR42651 - http://flybase.org/reports/FBgn0261503 non_protein_coding_gene - - - "CG42651, CR42651, pri-mir-10" - CR42651 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0027216 l(1)G0329 lethal (1) G0329 http://flybase.org/reports/FBgn0027216 - gene - - - l(1)G0329 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0001409 l(1)3Bd lethal (1) 3Bd http://flybase.org/reports/FBgn0001409 - gene - - - "zw-7, l(1)zw7, zw7, ZW-7, l(1)3Bd" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,germline clone,cell lethal,lethal - all die before end of P-stage,some die during pharate adult stage" "female reproductive system,egg,germline clone" FBgn0051874 Fum4 - http://flybase.org/reports/FBgn0051874 protein_coding_gene fumarate hydratase activity ; GO:0004333 | inferred from electronic annotation with InterPro:IPR005677 malate metabolic process ; GO:0006108 | inferred from biological aspect of ancestor with PANTHER:PTN000154499 fumarate metabolic process ; GO:0006106 | inferred from biological aspect of ancestor with PANTHER:PTN000154499 tricarboxylic acid cycle ; GO:0006099 | inferred from biological aspect of ancestor with PANTHER:PTN000154499 tricarboxylic acid cycle enzyme complex ; GO:0045239 | inferred from electronic annotation with InterPro:IPR005677 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000154501 "NEST:bs10e11, CG31874" "IPR000362:Fumarate lyase family, IPR008948:L-Aspartase-like, IPR024083:Fumarase/histidase, N-terminal, IPR018951:Fumarase C, C-terminal, IPR020557:Fumarate lyase, conserved site, IPR022761:Fumarate lyase, N-terminal, IPR005677:Fumarate hydratase, class II" CG31874 27-Aug-18 DroID_v2018_08 "Drer\LOC100535417, Drer\fh" Scer\FUM1 Cele\fum-1 - Mmus\Fh1 Hsap\FH viable FBgn0026189 prominin-like prominin-like http://flybase.org/reports/FBgn0026189 - protein_coding_gene - neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR008795 "bs29e02.y1, CG7740, prominin-like" IPR008795:Prominin CG7740 27-Aug-18 DroID_v2018_08 "Drer\prom2, Drer\prom1b, Drer\prom1a" - Cele\prmn-1 "Xtro\prom1, Xtro\prom2" "Mmus\Prom1, Mmus\Prom2" "Hsap\PROM1, Hsap\PROM2" FBgn0283535 Vha26 Vacuolar H[+]-ATPase 26kD subunit http://flybase.org/reports/FBgn0283535 protein_coding_gene "proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from electronic annotation with InterPro:IPR002842 proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | contributes_to inferred by curator from GO:0033181" "ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from electronic annotation with InterPro:IPR002842 apical protein localization ; GO:0045176 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype ATP hydrolysis coupled proton transport ; GO:0015991 | inferred by curator from GO:0033181 trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype" "plasma membrane ; GO:0005886 | inferred from direct assay plasma membrane proton-transporting V-type ATPase complex ; GO:0033181 | inferred from mutant phenotype vacuolar proton-transporting V-type ATPase, V1 domain ; GO:0000221 | inferred from sequence or structural similarity with SGD:S000005859" "Vha26, okg, vha26, CG1088, BcDNA.GH03683, anon-83Bb, VhaE, BcDNA:GH03683, vATPase, ATP6V1E1, chr3R:1419698..1419836, oak-gall" "IPR002842:ATPase, V1/A1 complex, subunit E" CG1088 27-Aug-18 DroID_v2018_08 "Drer\atp6v1e1, Drer\atp6v1e1b, Drer\mogat3b" Scer\VMA4 Cele\vha-8 Xtro\atp6v1e1 "Mmus\Atp6v1e1, Mmus\Atp6v1e2" "Hsap\ATP6V1E2, Hsap\ATP6V1E1" "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone,embryonic/larval dorsal trunk" FBgn0032491 CG16815 - http://flybase.org/reports/FBgn0032491 protein_coding_gene protein dimerization activity ; GO:0046983 | inferred from sequence or structural similarity - - "CG16815, DM27" - CG16815 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0036152 CG6175 - http://flybase.org/reports/FBgn0036152 protein_coding_gene - regulation of cell cycle ; GO:0051726 | inferred from direct assay imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype - "CG6175, anon-WO0257455.23" "IPR006578:MADF domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG6175 27-Aug-18 DroID_v2018_08 - - - - - - "behavior defective,recessive,partially lethal - majority die" FBgn0030094 CG11042 - http://flybase.org/reports/FBgn0030094 protein_coding_gene - - - CG11042 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039749 CG11498 - http://flybase.org/reports/FBgn0039749 protein_coding_gene - cellular response to stress ; GO:0033554 | inferred from electronic annotation with InterPro:IPR026169 mitophagy by induced vacuole formation ; GO:0035695 | inferred from biological aspect of ancestor with PANTHER:PTN001094748 mitochondrial protein catabolic process ; GO:0035694 | inferred from biological aspect of ancestor with PANTHER:PTN001094748 mitochondrial outer membrane ; GO:0005741 | inferred from biological aspect of ancestor with PANTHER:PTN001094748 CG11498 "IPR026169:Mitochondria-eating protein, IPR031981:Mitochondria-eating protein, C-terminal domain" CG11498 27-Aug-18 DroID_v2018_08 - - Cele\F49E10.4 - - - viable DRSC14315 E -0.48285746 0.163927676 3.171273854 0.461518065 0.81556617 0.224525858 FBgn0067379 l(2)309 lethal (2) 309 http://flybase.org/reports/FBgn0067379 gene - - - l(2)309 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0042169 CG18849 - http://flybase.org/reports/FBgn0042169 protein_coding_gene - - - CG18849 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060622 l(3)S088113 lethal (3) S088113 http://flybase.org/reports/FBgn0060622 gene - - - "0881/13, l(3)S088113" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0261915 l(3)16107 - http://flybase.org/reports/FBgn0261915 gene - - - l(3)16107 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal" FBgn0033316 Gle1 - http://flybase.org/reports/FBgn0033316 protein_coding_gene inositol hexakisphosphate binding ; GO:0000822 | inferred from biological aspect of ancestor with PANTHER:PTN000311158 phospholipid binding ; GO:0005543 | inferred from biological aspect of ancestor with PANTHER:PTN000311158 translation initiation factor binding ; GO:0031369 | inferred from biological aspect of ancestor with PANTHER:PTN000311158 regulation of translational initiation ; GO:0006446 | inferred from biological aspect of ancestor with PANTHER:PTN000311158 poly(A)+ mRNA export from nucleus ; GO:0016973 | inferred from sequence or structural similarity with UniProtKB:Q12315 mRNA export from nucleus ; GO:0006406 | inferred from biological aspect of ancestor with PANTHER:PTN000311158 regulation of translational termination ; GO:0006449 | inferred from biological aspect of ancestor with PANTHER:PTN000311158 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000311158 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q12315 nuclear pore ; GO:0005643 | inferred from sequence or structural similarity with UniProtKB:Q12315 nuclear pore cytoplasmic filaments ; GO:0044614 | inferred from biological aspect of ancestor with PANTHER:PTN000311158 "CG14749, GLE1, Gle1" IPR012476:GLE1-like CG14749 27-Aug-18 DroID_v2018_08 Drer\gle1 Scer\GLE1 - Xtro\gle1 Mmus\Gle1 Hsap\GLE1 viable FBgn0062675 EP2433 EP2433 http://flybase.org/reports/FBgn0062675 gene - - - "EP(2)2433, EP2433" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004147 l(2)57Aa lethal (2) 57Aa http://flybase.org/reports/FBgn0004147 - gene - - - l(2)57Aa - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,visible,recessive" FBgn0043860 pf-6 pairing failure-6 http://flybase.org/reports/FBgn0043860 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "CG6, pf-6" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0003863 alphaTry alphaTrypsin http://flybase.org/reports/FBgn0003863 FBgn0033621 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "SP102, Try, DmAlphaTry, alpha, alphaTry, CG18444" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG18444 27-Aug-18 DroID_v2018_08 "Drer\zgc:55888, Drer\prss60.2, Drer\ctrl, Drer\prss60.3, Drer\zgc:163079, Drer\zgc:123295, Drer\zgc:112038, Drer\tmprss4b, Drer\try, Drer\zgc:92590, Drer\zgc:153968, Drer\zgc:112160, Drer\LOC562139, Drer\prss60.1, Drer\si:dkeyp-93a5.2, Drer\si:ch211-165b19.9" - Cele\try-1 - "Mmus\Prss55, Mmus\Try4, Mmus\Prss1, Mmus\2210010C04Rik, Mmus\Gm5771, Mmus\Prss2, Mmus\Klk1b3, Mmus\Prss3, Mmus\Prss53, Mmus\Prss34, Mmus\Klk14, Mmus\Gm10334, Mmus\Habp2, Mmus\Prss36, Mmus\Try10" "Hsap\TPSG1, Hsap\PRSS45, Hsap\PRSS36, Hsap\PRSS3, Hsap\PRSS38, Hsap\PRSS53, Hsap\KLK2, Hsap\PRSS33, Hsap\PRSS48, Hsap\CMA1, Hsap\KLK1, Hsap\PRSS27, Hsap\PRSS1, Hsap\PRSS22, Hsap\PRSS8" " larval stage | third instar , adult stage " larval digestive system | restricted

FBgn0036266 CG5626 - http://flybase.org/reports/FBgn0036266 protein_coding_gene tRNA-intron endonuclease activity ; GO:0000213 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001077630 tRNA-type intron splice site recognition and cleavage ; GO:0000379 | inferred from biological aspect of ancestor with PANTHER:PTN001077630 tRNA-intron endonuclease complex ; GO:0000214 | inferred from biological aspect of ancestor with PANTHER:PTN001077630 CG5626 "IPR024336:tRNA-splicing endonuclease, subunit Sen54, N-terminal, IPR024337:tRNA-splicing endonuclease, subunit Sen54" CG5626 27-Aug-18 DroID_v2018_08 Drer\tsen54 Scer\SEN54 Cele\tsen-54 Xtro\tsen54 Mmus\Tsen54 Hsap\TSEN54 viable FBgn0037265 spartin spartin http://flybase.org/reports/FBgn0037265 protein_coding_gene Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab18 negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype negative regulation of BMP signaling pathway ; GO:0030514 | inferred from genetic interaction with wit neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype presynaptic membrane ; GO:0042734 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay early endosome ; GO:0005769 | inferred from direct assay terminal bouton ; GO:0043195 | inferred from direct assay "CG12001, spartin, Spartin" "IPR009686:Senescence/spartin-associated, IPR007330:MIT" CG12001 27-Aug-18 DroID_v2018_08 "Drer\spg20b, Drer\spg20a" - Cele\spg-20 Xtro\spg20 Mmus\Spg20 Hsap\SPG20 "viable,fertile,neuroanatomy defective,neurophysiology defective,locomotor behavior defective,progressive" "NMJ bouton,supernumerary,adult brain,progressive,supernumerary | third instar larval stage" FBgn0270926 AsnS Asparagine synthetase http://flybase.org/reports/FBgn0270926 protein_coding_gene protein homodimerization activity ; GO:0042803 | inferred from biological aspect of ancestor with PANTHER:PTN000206333 asparagine synthase (glutamine-hydrolyzing) activity ; GO:0004066 | inferred from biological aspect of ancestor with PANTHER:PTN000206333 asparagine biosynthetic process ; GO:0006529 | inferred from biological aspect of ancestor with PANTHER:PTN000206333 - "AsnS, AS, asparagine-synthetase, CG33486" "IPR029055:Nucleophile aminohydrolases, N-terminal, IPR006426:Asparagine synthase, glutamine-hydrolyzing, IPR001962:Asparagine synthase, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold, IPR017932:Glutamine amidotransferase type 2 domain, IPR033738:Asparagine synthase, N-terminal domain" CG33486 27-Aug-18 DroID_v2018_08 Drer\asns "Scer\ASN1, Scer\YML096W, Scer\ASN2" "Cele\asns-1, Cele\asns-2" Xtro\asns Mmus\Asns Hsap\ASNS FBgn0030763 CG9782 - http://flybase.org/reports/FBgn0030763 protein_coding_gene - - - CG9782 - CG9782 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0082952 snoRNA:Me18S-A1061 snoRNA:Me18S-A1061 http://flybase.org/reports/FBgn0082952 snoRNA_gene - - - "snoRNA:Me18S-A1061, Me18S-Am1061, Me18S-A1061 (DmSnR54), CR34537, DmSnR54, Dm_18S.001" - CR34537 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035371 AhcyL1 Adenosylhomocysteinase like 1 http://flybase.org/reports/FBgn0035371 protein_coding_gene "adenosylhomocysteinase activity ; GO:0004013 | inferred from electronic annotation with InterPro:IPR000043, InterPro:IPR020082" "one-carbon metabolic process ; GO:0006730 | inferred from electronic annotation with InterPro:IPR000043, InterPro:IPR020082 S-adenosylmethionine cycle ; GO:0033353 | inferred from biological aspect of ancestor with PANTHER:PTN000602759" cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000602759 "CG9977, dAhcyL1, AhcyL1" "IPR000043:Adenosylhomocysteinase-like, IPR015878:S-adenosyl-L-homocysteine hydrolase, NAD binding domain, IPR016040:NAD(P)-binding domain, IPR020082:S-adenosyl-L-homocysteine hydrolase, conserved site" CG9977 27-Aug-18 DroID_v2018_08 "Drer\ahcyl1, Drer\zgc:158222, Drer\ahcyl2, Drer\ahcy" Scer\SAH1 - "Xtro\ahcyl2, Xtro\ahcy, Xtro\ahcyl1" "Mmus\Ahcyl2, Mmus\Gm4737, Mmus\Ahcyl1, Mmus\Ahcy" "Hsap\AHCYL2, Hsap\AHCYL1, Hsap\AHCY" viable FBgn0060328 l(3)S146411b lethal (3) S146411b http://flybase.org/reports/FBgn0060328 gene - - - "1464/11, l(3)S146411b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0259309 EP-476 - http://flybase.org/reports/FBgn0259309 gene - - - EP-476 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing,wing margin" FBgn0034182 SmydA-7 "SET and MYND domain containing, arthropod-specific, member 7" http://flybase.org/reports/FBgn0034182 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "SmydA-7, CG9640" - CG9640 27-Aug-18 DroID_v2018_08 "Drer\smyd2a, Drer\erlin1, Drer\erlin2, Drer\smyd2b, Drer\smyd3, Drer\smyd1a, Drer\smyd4, Drer\smyd1b" "Scer\SET5, Scer\SET6" "Cele\set-18, Cele\set-10, Cele\erl-1" "Xtro\smyd1, Xtro\erlin2, Xtro\smyd5, Xtro\erlin1, Xtro\smyd4" "Mmus\Erlin2, Mmus\Erlin1, Mmus\Smyd5, Mmus\Smyd2, Mmus\Smyd3, Mmus\Zmynd15, Mmus\Smyd4, Mmus\Smyd1" "Hsap\SMYD5, Hsap\SMYD1, Hsap\ZMYND15, Hsap\SMYD2, Hsap\ERLIN1, Hsap\SMYD4, Hsap\SMYD3" viable FBgn0035550 CG11349 - http://flybase.org/reports/FBgn0035550 protein_coding_gene - - - CG11349 - CG11349 27-Aug-18 DroID_v2018_08 "Drer\col1a1b, Drer\col9a2, Drer\col11a1a, Drer\col11a1b, Drer\col7a1l, Drer\wu:fc38h03, Drer\col2a1a, Drer\col17a1b, Drer\col1a2, Drer\col12a1b, Drer\si:ch211-196i2.1, Drer\LOC101883924, Drer\col4a6, Drer\col28a1a, Drer\col5a1, Drer\col6a1, Drer\col27a1b, Drer\col9a1a, Drer\col16a1, Drer\col4a2, Drer\col4a5, Drer\zgc:153049, Drer\col1a1a, Drer\si:ch211-106n13.3, Drer\col5a2b, Drer\col2a1b, Drer\col14a1a, Drer\col11a2, Drer\si:dkey-225n22.4, Drer\col6a2, Drer\col6a3, Drer\col27a1a, Drer\LOC101884357, Drer\col6a4a, Drer\LOC100538221, Drer\si:dkey-61l1.4, Drer\col5a2a, Drer\col9a1b" - - "Xtro\col11a2, Xtro\col1a1, Xtro\col2a1, Xtro\col6a2, Xtro\col24a1, Xtro\col5a1, Xtro\col4a1, Xtro\col1a2, Xtro\LOC100486063, Xtro\col27a1, Xtro\col14a1, Xtro\col4a5, Xtro\col3a1, Xtro\col4a6, Xtro\col4a2, Xtro\col7a1" "Mmus\Col6a6, Mmus\Col11a1, Mmus\Col6a1, Mmus\Col4a2, Mmus\Col1a2, Mmus\Col3a1, Mmus\Col2a1, Mmus\Col6a3, Mmus\Tnn, Mmus\Col6a5, Mmus\Col5a3, Mmus\Col4a1, Mmus\Col4a4, Mmus\Col4a3, Mmus\Col1a1, Mmus\Col17a1, Mmus\Col11a2, Mmus\Col9a1, Mmus\Col5a2, Mmus\Col28a1, Mmus\Col16a1, Mmus\Col7a1, Mmus\Col9a3, Mmus\Col4a6, Mmus\Col6a4, Mmus\Col20a1, Mmus\Col23a1, Mmus\Col19a1, Mmus\8030474K03Rik, Mmus\Col13a1, Mmus\Col22a1, Mmus\Vwa1, Mmus\Col5a1, Mmus\Col4a5, Mmus\Col27a1, Mmus\Col24a1, Mmus\4933412E24Rik, Mmus\Col14a1, Mmus\Vwa2, Mmus\Col25a1" "Hsap\COL2A1, Hsap\COL4A2, Hsap\COL20A1, Hsap\COL11A1, Hsap\COL1A1, Hsap\COL4A6, Hsap\COL9A3, Hsap\VWA1, Hsap\COL1A2, Hsap\VWA2, Hsap\COL6A1, Hsap\COL4A4, Hsap\COL9A2, Hsap\COL16A1, Hsap\COL11A2, Hsap\COL6A3, Hsap\COL14A1, Hsap\COL17A1, Hsap\COL23A1, Hsap\COL4A5, Hsap\COL4A3, Hsap\COL5A2, Hsap\COL19A1, Hsap\COL4A1, Hsap\COL6A6, Hsap\COL27A1, Hsap\COL25A1, Hsap\COL5A3, Hsap\COL5A1, Hsap\COL7A1, Hsap\COLQ, Hsap\COL24A1, Hsap\COL3A1, Hsap\COL6A5, Hsap\COL9A1, Hsap\COL22A1" "viable,visible" trichogen cell FBgn0004081 XDm XDm element http://flybase.org/reports/FBgn0004081 - repeat_region - - - XDm - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0024720 Su(var)99C99E Su(var)99C99E http://flybase.org/reports/FBgn0024720 - gene - - - Su(var)99C99E - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0003583 Su(stn) Suppressor of stoned http://flybase.org/reports/FBgn0003583 - gene - - - Su(stn) - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0020616 SA Stromalin http://flybase.org/reports/FBgn0020616 FBgn0020933 protein_coding_gene chromatin binding ; GO:0003682 | inferred from direct assay chromatin binding ; GO:0003682 | inferred from sequence or structural similarity with SGD:S000001288 synaptonemal complex assembly ; GO:0007130 | inferred from mutant phenotype mitotic sister chromatid cohesion ; GO:0007064 | inferred from sequence or structural similarity with SGD:S000001288 neuron remodeling ; GO:0016322 | inferred from mutant phenotype "spindle pole ; GO:0000922 | inferred from direct assay cohesin complex ; GO:0008278 | non-traceable author statement condensed nuclear chromosome, centromeric region ; GO:0000780 | inferred from direct assay pericentric heterochromatin ; GO:0005721 | inferred from direct assay cohesin complex ; GO:0008278 | inferred from direct assay transcriptionally active chromatin ; GO:0035327 | inferred from direct assay nuclear mitotic cohesin complex ; GO:0034990 | inferred from sequence or structural similarity with SGD:S000001288" "DmSA, SCC3, DSA, ESTS:92H2T, CG3423, SA, Scc3, DSA1" "IPR013721:STAG, IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical, IPR020839:Stromalin conservative domain" CG3423 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-269e2.1, Drer\stag2a, Drer\stag1b, Drer\stag2b, Drer\stag1a" Scer\IRR1 Cele\scc-3 "Xtro\stag1, Xtro\stag3" "Mmus\Stag2, Mmus\Stag3, Mmus\Stag1" "Hsap\STAG3, Hsap\STAG1, Hsap\STAG2" "lethal - all die before end of pupal stage,partially,some die during pupal stage,planar polarity defective" DRSC03424 K -0.223030754 0.870827593 0.051109107 1.44912264 1.790112427 2.615684226 FBgn0029672 CG2875 - http://flybase.org/reports/FBgn0029672 protein_coding_gene - "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000462 | inferred from biological aspect of ancestor with PANTHER:PTN000278911 neurogenesis ; GO:0022008 | inferred from mutant phenotype" nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000278911 Noc4p-Nop14p complex ; GO:0030692 | inferred from biological aspect of ancestor with PANTHER:PTN000278911 small-subunit processome ; GO:0032040 | inferred from biological aspect of ancestor with PANTHER:PTN000278911 CG2875 "IPR005612:CCAAT-binding factor, IPR027193:Nucleolar complex protein 4, IPR011989:Armadillo-like helical" CG2875 27-Aug-18 DroID_v2018_08 Drer\noc4l Scer\NOC4 Cele\T20B12.3 Xtro\noc4l Mmus\Noc4l Hsap\NOC4L "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0053170 CG33170 - http://flybase.org/reports/FBgn0053170 protein_coding_gene - - - "CG8244, BcDNA:AT30788, CG33170" IPR027854:Protein of unknown function DUF4535 CG33170 27-Aug-18 DroID_v2018_08 - - Cele\B0205.12 - - Hsap\C7orf73 viable FBgn0027998 l(3)S122404 lethal (3) S122404 http://flybase.org/reports/FBgn0027998 gene - - - "1224/04, l(3)S122404" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0083990 lncRNA:sphinx sphinx http://flybase.org/reports/FBgn0083990 non_protein_coding_gene - male courtship behavior ; GO:0008049 | inferred from mutant phenotype - "sphinx, CR34154, spx, Sphinx" - CR34154 27-Aug-18 DroID_v2018_08 - - - - - - "courtship behavior defective,male limited" FBgn0001347 l(1)1Eb lethal (1) 1Eb http://flybase.org/reports/FBgn0001347 - gene - - - "HM-14, l(1)1Eb" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage,cell lethal,germline clone,recessive,lethal" FBgn0266156 lncRNA:CR44862 - http://flybase.org/reports/FBgn0266156 non_protein_coding_gene - - - CR44862 - CR44862 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034168 CG15614 - http://flybase.org/reports/FBgn0034168 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from electronic annotation with InterPro:IPR000276 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR000276 "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR017452" CG15614 "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG15614 27-Aug-18 DroID_v2018_08 - - "Cele\T10E10.3, Cele\K03H6.5, Cele\srw-65, Cele\D1014.2, Cele\R13H7.2, Cele\F40A3.7, Cele\B0563.6, Cele\glb-33, Cele\W10C4.1, Cele\F59B2.13, Cele\K03H6.1" - - - viable FBgn0002250 l(3)68Eb lethal (3) 68Eb http://flybase.org/reports/FBgn0002250 - gene - - - "rsg12, l(3)rsg12, l(3)68Eb" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0000956 fs(2)E3 female sterile (2) E3 http://flybase.org/reports/FBgn0000956 - gene - - - "fs2.3, fs(2)E3" - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive,visible" "wing,female reproductive system" FBgn0036706 ND-24L NADH dehydrogenase (ubiquinone) 24 kDa subunit-like http://flybase.org/reports/FBgn0036706 protein_coding_gene NADH dehydrogenase (ubiquinone) activity ; GO:0008137 | inferred from biological aspect of ancestor with PANTHER:PTN000042665 NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:P19404 "mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from biological aspect of ancestor with PANTHER:PTN000042666 mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with UniProtKB:P19404" mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:P19404 mitochondrial respiratory chain complex I ; GO:0005747 | inferred from biological aspect of ancestor with PANTHER:PTN000042666 "CG6485, NUHM, ND-24L" "IPR002023:NADH-quinone oxidoreductase subunit E-like, IPR012336:Thioredoxin-like fold" CG6485 27-Aug-18 DroID_v2018_08 Drer\ndufv2 - Cele\F53F4.10 Xtro\ndufv2 Mmus\Ndufv2 Hsap\NDUFV2 viable FBgn0028424 JhI-26 Juvenile hormone-inducible protein 26 http://flybase.org/reports/FBgn0028424 protein_coding_gene molecular_function ; GO:0003674 | no biological data available regulation of female receptivity ; GO:0045924 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG3767, JhI-26" "IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain, IPR015897:CHK kinase-like" CG3767 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0025168 l(2)38EFc lethal (2) 38EFc http://flybase.org/reports/FBgn0025168 - gene - - - l(2)38EFc - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0266325 asRNA:CR44990 - http://flybase.org/reports/FBgn0266325 non_protein_coding_gene - - - CR44990 - CR44990 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002355 l(3)87Eb lethal (3) 87Eb http://flybase.org/reports/FBgn0002355 - gene - - - "B16, B16-1, l(3)B16-1, l(3)B16, l(3)87Eb" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0041629 Hexo2 Hexosaminidase 2 http://flybase.org/reports/FBgn0041629 protein_coding_gene beta-N-acetylglucosaminidase activity ; GO:0016231 | inferred from direct assay "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR013781, InterPro:IPR015883 negative regulation of growth of symbiont in host ; GO:0044130 | inferred from mutant phenotype multicellular organism reproduction ; GO:0032504 | inferred from expression pattern" plasma membrane ; GO:0005886 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay "HEX2, HEX 2, DmHex2, CG1787, Hexo2, HEXO2" "IPR025705:Beta-hexosaminidase, IPR015883:Glycoside hydrolase family 20, catalytic domain, IPR017853:Glycoside hydrolase superfamily, IPR029018:Chitobiase/beta-hexosaminidase domain 2-like, IPR029019:Beta-hexosaminidase, eukaryotic type, N-terminal" CG1787 27-Aug-18 DroID_v2018_08 "Drer\hexb, Drer\hexa" - Cele\hex-1 Xtro\hexb "Mmus\Hexb, Mmus\Hexa" "Hsap\HEXA, Hsap\HEXB" "viable,fertile" FBgn0032261 CG6094 - http://flybase.org/reports/FBgn0032261 protein_coding_gene "translation release factor activity, codon nonspecific ; GO:0016150 | inferred from sequence or structural similarity with UniProtKB:Q14197" mitochondrial translational termination ; GO:0070126 | inferred from sequence or structural similarity with UniProtKB:Q14197 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q14197 "CG6094, FBgn 32261, dICT1" IPR000352:Peptide chain release factor class I/class II CG6094 27-Aug-18 DroID_v2018_08 Drer\ict1 Scer\PTH4 Cele\R02F2.9 Xtro\ict1 Mmus\Mrpl58 Hsap\MRPL58 "viable,visible" trichogen cell FBgn0027153 l(3)61Db lethal (3) 61Db http://flybase.org/reports/FBgn0027153 - gene - - - l(3)61Db - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0000364 Cpt Clipt http://flybase.org/reports/FBgn0000364 - gene - - - "Cpt, CPTI" - - 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,lethal,recessive" macrochaeta FBgn0086350 tef teflon http://flybase.org/reports/FBgn0086350 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 male meiosis chromosome separation ; GO:0051308 | inferred from mutant phenotype male meiosis chromosome segregation ; GO:0007060 | inferred from mutant phenotype male meiosis I ; GO:0007141 | inferred from mutant phenotype autosome ; GO:0030849 | inferred from direct assay "tef, CG8961, l(2)k15914" IPR013087:Zinc finger C2H2-type CG8961 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0028285 l(1)G0411 lethal (1) G0411 http://flybase.org/reports/FBgn0028285 gene - - - l(1)G0411 - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,male,female,recessive" FBgn0265559 21.28 - http://flybase.org/reports/FBgn0265559 gene - - - 21.28 - - 27-Aug-18 DroID_v2018_08 - - - - - - learning defective FBgn0011602 IM137 IM137 http://flybase.org/reports/FBgn0011602 - gene - - - IM137 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005115 l(1)2269 lethal (1) 2269 http://flybase.org/reports/FBgn0005115 - gene - - - l(1)2269 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,tumorigenic" imaginal disc FBgn0004651 Fs(2)M Female sterile of Meyer http://flybase.org/reports/FBgn0004651 "FBgn0000929, FBgn0000995" gene - - - "Fs, Fs(2)D-M, Fs(2)M" - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,dominant,male fertile,visible" FBgn0000657 fin finer http://flybase.org/reports/FBgn0000657 - gene - - - fin - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,male sterile,viable,male" macrochaeta FBgn0040571 CG17193 - http://flybase.org/reports/FBgn0040571 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE41733, CG17193" - CG17193 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0034759 CG13511 - http://flybase.org/reports/FBgn0034759 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13511 IPR006629:LPS-induced tumour necrosis factor alpha factor CG13511 27-Aug-18 DroID_v2018_08 "Drer\litaf, Drer\si:ch211-202h22.7, Drer\cdip1, Drer\si:ch211-202h22.9, Drer\ubald1a, Drer\si:ch211-202h22.8, Drer\si:dkeyp-75b4.8, Drer\si:ch211-157c3.4" - "Cele\F16F9.1, Cele\Y87G2A.19, Cele\B0348.2, Cele\B0348.1, Cele\Y87G2A.18, Cele\Y37D8A.8, Cele\Y22D7AL.15, Cele\Y37D8A.6, Cele\F36G3.3, Cele\Y40H7A.11, Cele\C08E8.1, Cele\Y37D8A.26" "Xtro\cdip1, Xtro\litaf" "Mmus\Litaf, Mmus\Cdip1" "Hsap\LITAF, Hsap\CDIP1" viable FBgn0285943 knon ms(2)1400 http://flybase.org/reports/FBgn0011664 - gene - - - ms(2)1400 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266515 s-562.2 - http://flybase.org/reports/FBgn0266515 gene - - - s-562.2 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031466 CG3119 - http://flybase.org/reports/FBgn0031466 protein_coding_gene glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity ; GO:0016263 | inferred from biological aspect of ancestor with PANTHER:PTN000547277 "O-glycan processing, core 1 ; GO:0016267 | inferred from biological aspect of ancestor with PANTHER:PTN000547277" membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR003378 "CG3119, dC1GalT7" IPR003378:Fringe-like CG3119 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-202e17.1, Drer\LOC564281, Drer\c1galt1c1, Drer\c1galt1b, Drer\c1galt1a" - "Cele\Y38C1AB.5, Cele\F56H6.1, Cele\C38H2.2, Cele\W09D10.5, Cele\C17A2.3, Cele\F37A4.3, Cele\bus-4, Cele\E03H4.3, Cele\C02H6.1, Cele\C16D9.6, Cele\T09E11.12, Cele\Y38C1AB.1" "Xtro\LOC100496837, Xtro\c1galt1" "Mmus\C1galt1c1, Mmus\C1galt1" "Hsap\C1GALT1, Hsap\C1GALT1C1" viable FBgn0061089 l(3)S011513a lethal (3) S011513a http://flybase.org/reports/FBgn0061089 gene - - - "0115/13, l(3)S011513a" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0260600 2L2775 - http://flybase.org/reports/FBgn0260600 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L2775 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0039024 CG4721 - http://flybase.org/reports/FBgn0039024 protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR018497" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR008753, InterPro:IPR018497 compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype" - "anon-EST:Posey132, CG4721" "IPR000718:Peptidase M13, IPR008753:Peptidase M13, N-terminal domain, IPR018497:Peptidase M13, C-terminal domain, IPR024079:Metallopeptidase, catalytic domain" CG4721 27-Aug-18 DroID_v2018_08 "Drer\ece1, Drer\phex, Drer\ece2b, Drer\mmel1" - "Cele\nep-7, Cele\nep-20, Cele\nep-24, Cele\nep-18, Cele\nep-23, Cele\nep-5, Cele\nep-3, Cele\nep-8, Cele\nep-13, Cele\nep-12, Cele\nep-19, Cele\nep-6, Cele\nep-17, Cele\nep-10, Cele\nep-9, Cele\nep-21, Cele\nep-26, Cele\nep-16" "Xtro\ece2, Xtro\ece1, Xtro\ecel1, Xtro\mmel1" "Mmus\Ecel1, Mmus\Ece1, Mmus\Kel, Mmus\Mme, Mmus\Mmel1, Mmus\Phex, Mmus\Ece2" "Hsap\ECE1, Hsap\ECEL1, Hsap\MME, Hsap\PHEX, Hsap\MMEL1, Hsap\KEL, Hsap\ECE2" visible eye FBgn0054030 CG34030 - http://flybase.org/reports/FBgn0054030 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BP1084, HDC08855, CG34030" - CG34030 27-Aug-18 DroID_v2018_08 - - Cele\xbx-6 - - - FBgn0022730 l(2)PGM-21 lethal (2) PGM-21 http://flybase.org/reports/FBgn0022730 - gene - - - "PGM-21, l(2)PGM-21" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0014257 l(2)FE3 lethal (2) FE3 http://flybase.org/reports/FBgn0014257 - gene - - - "FE3, l(2)FE3" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0002582 M(1)5A Minute (1) 5A http://flybase.org/reports/FBgn0002582 - gene - - - M(1)5A - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032940 Mondo Mondo http://flybase.org/reports/FBgn0032940 protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from sequence or structural similarity with MGI:MGI:1927999 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN001039502 transcription factor binding ; GO:0008134 | inferred from sequence or structural similarity with MGI:MGI:1927999 DNA binding ; GO:0003677 | contributes_to inferred from sequence or structural similarity with MGI:MGI:1927999" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from sequence or structural similarity with Max glucose homeostasis ; GO:0042593 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity with MGI:MGI:1927999 response to sucrose ; GO:0009744 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from expression pattern regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001039502 triglyceride homeostasis ; GO:0070328 | inferred from mutant phenotype" cytosol ; GO:0005829 | inferred from direct assay nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001039502 transcription factor complex ; GO:0005667 | inferred from sequence or structural similarity with MGI:MGI:1927999 "154826_at, CG18362, dmondo, anon-39Da, Mondo, bHLHd12, Mio, mio, ChREBP, mlx, mondo" "IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG18362 27-Aug-18 DroID_v2018_08 "Drer\mlxip, Drer\LOC100535945" - "Cele\mxl-2, Cele\mml-1" Xtro\mlxip "Mmus\Mlxip, Mmus\Mlxipl" "Hsap\MLXIPL, Hsap\MLXIP" "lethal,recessive,feeding behavior defective,viable,fertile,developmental rate defective,conditional,partially lethal,lethal - all die during larval stage,chemical conditional,stress response defective,chemical sensitive,small body" DRSC02668 IEK -1.692120041 -1.219683889 -1.303151459 -1.73792302 -0.136675375 -1.661653564 FBgn0266414 lncRNA:CR45054 - http://flybase.org/reports/FBgn0266414 non_protein_coding_gene - - - "CG45054, CR45054" - CR45054 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039224 CG13634 - http://flybase.org/reports/FBgn0039224 protein_coding_gene - - - CG13634 - CG13634 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0011593 fs(3)2877 fs(3)2877 http://flybase.org/reports/FBgn0011593 - gene - - - fs(3)2877 - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive" egg FBgn0034266 CG4975 - http://flybase.org/reports/FBgn0034266 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - cytoplasm ; GO:0005737 | inferred from direct assay "CG4975, Atxn10" "IPR016024:Armadillo-type fold, IPR019156:Ataxin-10 domain, IPR011989:Armadillo-like helical" CG4975 27-Aug-18 DroID_v2018_08 Drer\atxn10 Scer\CTR86 - Xtro\atxn10 Mmus\Atxn10 Hsap\ATXN10 "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0260297 GSd232 - http://flybase.org/reports/FBgn0260297 gene - - - GSd232 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0259822 Ca-beta Ca2+-channel-protein-beta-subunit http://flybase.org/reports/FBgn0259822 protein_coding_gene high voltage-gated calcium channel activity ; GO:0008331 | inferred from biological aspect of ancestor with PANTHER:PTN000930213 voltage-gated calcium channel activity ; GO:0005245 | inferred from mutant phenotype neuromuscular junction development ; GO:0007528 | inferred from biological aspect of ancestor with PANTHER:PTN000930213 regulation of voltage-gated calcium channel activity ; GO:1901385 | inferred from biological aspect of ancestor with PANTHER:PTN000930213 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype calcium-mediated signaling ; GO:0019722 | inferred from mutant phenotype neuron remodeling ; GO:0016322 | inferred from mutant phenotype chemical synaptic transmission ; GO:0007268 | inferred from biological aspect of ancestor with PANTHER:PTN000930213 calcium ion transmembrane transport ; GO:0070588 | inferred from mutant phenotype voltage-gated calcium channel complex ; GO:0005891 | inferred from electronic annotation with InterPro:IPR000584 voltage-gated calcium channel complex ; GO:0005891 | traceable author statement "Ca-beta, CG42403, CG6320, dmcab1, DmCa1beta, CaBeta, CG14922, CG14923, CG33305, ca-beta" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR000584:Voltage-dependent calcium channel, L-type, beta subunit, IPR001452:SH3 domain, IPR008145:Guanylate kinase/L-type calcium channel beta subunit" CG42403 27-Aug-18 DroID_v2018_08 "Drer\cacnb3b, Drer\cacnb2a, Drer\cacnb2b, Drer\cacnb4b, Drer\cacnb1, Drer\cacnb3a, Drer\cacnb4a" - "Cele\ccb-1, Cele\ccb-2" "Xtro\cacnb3, Xtro\cacnb2, Xtro\cacnb4" "Mmus\Cacnb2, Mmus\Cacnb1, Mmus\Cacnb4, Mmus\Cacnb3" "Hsap\CACNB3, Hsap\CACNB1, Hsap\CACNB2, Hsap\CACNB4" DRSC03285 K 0.223235351 0.633243612 0.09161656 0.198400026 -1.625386545 -0.251280382 FBgn0263081 CG43349 - http://flybase.org/reports/FBgn0263081 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43349 - CG43349 27-Aug-18 DroID_v2018_08 - - - - - Hsap\PHGR1 FBgn0040566 CG14328 - http://flybase.org/reports/FBgn0040566 protein_coding_gene - - - CG14328 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039290 CG13654 - http://flybase.org/reports/FBgn0039290 protein_coding_gene - - plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000371278 CG13654 "IPR000742:EGF-like domain, IPR013032:EGF-like, conserved site, IPR021910:Protein of unknown function DUF3522" CG13654 27-Aug-18 DroID_v2018_08 "Drer\tmem8c, Drer\si:dkey-84j12.1, Drer\tmem8a" - - Xtro\tmem8a "Mmus\Tmem8b, Mmus\Tmem8c, Mmus\Tmem8" "Hsap\TMEM8B, Hsap\TMEM8A, Hsap\TMEM8C" viable FBgn0044046 Ilp7 Insulin-like peptide 7 http://flybase.org/reports/FBgn0044046 protein_coding_gene hormone activity ; GO:0005179 | inferred from electronic annotation with InterPro:IPR016179 insulin receptor binding ; GO:0005158 | inferred from sequence or structural similarity with HGNC:6081 insulin receptor signaling pathway ; GO:0008286 | inferred from sequence or structural similarity with HGNC:6081 extracellular space ; GO:0005615 | inferred from sequence or structural similarity with HGNC:6081 "Ilp, DILP, dilp, dilp-7, Dilp, Dilp 7, dilp7, CG13317, Ilp7, ILP7, DILP7, Ilp-7, ilp7, Dilp7, DILP-7, dILP7" IPR016179:Insulin-like CG13317 27-Aug-18 DroID_v2018_08 - - - - - - " embryonic stage , larval stage | third instar " " organism

, ventral nerve cord | restricted & segmentally repeated

" "large body,behavior defective,female,viable" FBgn0040777 CG14767 - http://flybase.org/reports/FBgn0040777 protein_coding_gene - - "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR004687, InterPro:IPR018400" "CG8575, CG14767, dmCG14767" IPR004687:Lysosomal-associated transmembrane protein 4/5 CG14767 27-Aug-18 DroID_v2018_08 "Drer\laptm4a, Drer\laptm4b, Drer\LOC100151049" - "Cele\C05E11.3, Cele\C39D10.6" "Xtro\laptm5, Xtro\laptm4a" "Mmus\Laptm5, Mmus\Laptm4a, Mmus\Laptm4b" "Hsap\LAPTM5, Hsap\LAPTM4A, Hsap\LAPTM4B" "viable,fertile" FBgn0264644 etiolated etiolated http://flybase.org/reports/FBgn0264644 gene - trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype - etiolated - - 27-Aug-18 DroID_v2018_08 - - - - - - "embryonic/larval tracheal system,eye,somatic clone" FBgn0027844 CAH1 Carbonic anhydrase 1 http://flybase.org/reports/FBgn0027844 FBgn0027926 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR018338 carbonate dehydratase activity ; GO:0004089 | inferred from direct assay carbonate dehydratase activity ; GO:0004089 | inferred from sequence or structural similarity one-carbon metabolic process ; GO:0006730 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence model "BG:DS00941.1, CAH, CG7820, CAH1, Gh7" "IPR001148:Alpha carbonic anhydrase, IPR023561:Carbonic anhydrase, alpha-class, IPR018338:Carbonic anhydrase, alpha-class, conserved site" CG7820 27-Aug-18 DroID_v2018_08 "Drer\ca5a, Drer\ca6, Drer\ca9, Drer\cahz, Drer\ca4b, Drer\ca10a, Drer\ca14, Drer\ca15b, Drer\ca15c, Drer\car15, Drer\ca4c, Drer\si:ch211-173d10.4, Drer\ca7, Drer\ca10b, Drer\ca16b, Drer\zgc:153760, Drer\ca12, Drer\ca2, Drer\ca15a, Drer\ca4a, Drer\ptprga, Drer\ca8" - "Cele\cah-6, Cele\cah-4, Cele\cah-5, Cele\cah-3" "Xtro\ca5b, Xtro\ca6, Xtro\ca8, Xtro\ca2, Xtro\ca1, Xtro\ca10, Xtro\ca7, Xtro\ca14, Xtro\ca3, Xtro\ca12, Xtro\LOC779564, Xtro\ca4, Xtro\ca11, Xtro\car1_predicted" "Mmus\Car8, Mmus\Car2, Mmus\Ptprg, Mmus\Car4, Mmus\Car11, Mmus\Car15, Mmus\Car9, Mmus\Car5a, Mmus\Car14, Mmus\Car10, Mmus\Car5b, Mmus\Car1, Mmus\Car7, Mmus\Car12, Mmus\Car6, Mmus\Car13, Mmus\Car3" "Hsap\CA10, Hsap\CA5B, Hsap\CA9, Hsap\CA6, Hsap\CA4, Hsap\CA14, Hsap\CA5A, Hsap\CA11, Hsap\CA8, Hsap\CA2, Hsap\CA13, Hsap\CA7, Hsap\CA12, Hsap\CA1, Hsap\PTPRG, Hsap\CA3" FBgn0063083 lncRNA:CR33948 putative noncoding RNA 015:3L http://flybase.org/reports/FBgn0063083 non_protein_coding_gene - - - "CR33948, BcDNA:LP12023, pncr015:3L" - CR33948 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0025454 Cyp6g1 Cyp6g1 http://flybase.org/reports/FBgn0025454 "FBgn0003288, FBgn0067801, FBgn0067802" protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN001209891" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 response to insecticide ; GO:0017085 | inferred from mutant phenotype response to DDT ; GO:0046680 | inferred from mutant phenotype insecticide catabolic process ; GO:0046701 | inferred from direct assay response to organophosphorus ; GO:0046683 | inferred from mutant phenotype response to mercury ion ; GO:0046689 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from expression pattern" - "Cyp6g1, Cyp6gl, CG8453, Rst(2)DDT, 6g1, cyp6g1, RDDT, RI, RI[II], RI[DDT], Cyp6-like, anon-WO03025223.17, anon-WO03025223.16, DDT-R, CYP6G1, Cyp6G1, CYP6g1, Dmel-Cyp6g1" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG8453 27-Aug-18 DroID_v2018_08 "Drer\cyp3c2, Drer\cyp3c4, Drer\cyp3c3, Drer\cyp3a65, Drer\tbxas1, Drer\cyp3c1" Scer\ERG11 "Cele\cyp-13A11, Cele\cyp-13B2, Cele\cyp-13A5, Cele\cyp-25A3, Cele\cyp-43A1, Cele\cyp-25A6, Cele\cyp-13A12, Cele\cyp-25A1, Cele\cyp-13A10, Cele\cyp-13A6, Cele\cyp-13A7, Cele\cyp-13A8, Cele\cyp-25A2, Cele\cyp-13A4, Cele\cyp-13B1, Cele\cyp-13A1, Cele\cyp-13A3, Cele\cyp-25A4, Cele\cyp-13A2, Cele\cyp-44A1" "Xtro\tbxas1, Xtro\LOC100494419, Xtro\cyp3a5, Xtro\cyp3a4" "Mmus\Cyp3a57, Mmus\Cyp3a41a, Mmus\Cyp3a59, Mmus\Tbxas1, Mmus\Cyp3a11, Mmus\Cyp3a25, Mmus\Cyp3a41b, Mmus\Cyp3a44, Mmus\Cyp3a13, Mmus\Cyp3a16" "Hsap\CYP3A7-CYP3A51P, Hsap\TBXAS1, Hsap\CYP3A43, Hsap\CYP3A7, Hsap\CYP3A5, Hsap\CYP3A4" "viable,fertile,chemical sensitive,chemical resistant,maternal effect" FBgn0043058 Trl::ttk Trl::ttk http://flybase.org/reports/FBgn0043058 engineered_fusion_gene - - - Trl::ttk - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,lethal" eye FBgn0267242 asRNA:CR45682 - http://flybase.org/reports/FBgn0267242 non_protein_coding_gene - - - CR45682 - CR45682 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002864 Mst95EF Male-specific RNA 95EF http://flybase.org/reports/FBgn0002864 - gene - - - "mst345, Mst95EF" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001488 l(1)10Ah lethal (1) 10Ah http://flybase.org/reports/FBgn0001488 - gene - - - "l(1)G12, l(1)10Ah" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0035537 CG11342 - http://flybase.org/reports/FBgn0035537 protein_coding_gene "methyltransferase activity ; GO:0008168 | inferred from electronic annotation with InterPro:IPR010675, InterPro:IPR024160" - - CG11342 "IPR010675:RNA methyltransferase bin3, C-terminal, IPR024160:Bin3-type S-adenosyl-L-methionine binding domain, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG11342 27-Aug-18 DroID_v2018_08 "Drer\si, Drer\bcdin3d, Drer\mepce, Drer\si:ch1073-157b13.1" - - Xtro\bcdin3d "Mmus\Mepce, Mmus\Bcdin3d" "Hsap\MEPCE, Hsap\BCDIN3D" viable FBgn0261292 CheB53a Chemosensory protein B 53a http://flybase.org/reports/FBgn0261292 protein_coding_gene lipid binding ; GO:0008289 | inferred from sequence alignment with HGNC:14537 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with CheB42a detection of pheromone ; GO:0043695 | inferred from expression pattern extracellular region ; GO:0005576 | inferred from sequence model extracellular space ; GO:0005615 | inferred from sequence or structural similarity with CheB42a "CheB53a, CG33457, CG16797, CG33550" "IPR006601:Uncharacterised protein family DM11, Drosophila melanogaster" CG33550 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033794 CG13326 - http://flybase.org/reports/FBgn0033794 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000593603 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000593603 CG13326 "IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical" CG13326 27-Aug-18 DroID_v2018_08 "Drer\ctnnd2b, Drer\armc4, Drer\jupb, Drer\pkp4, Drer\armc3, Drer\ctnnd2a, Drer\arvcfb" Scer\VAC8 "Cele\hmp-2, Cele\jac-1" "Xtro\ctnnb1, Xtro\armc3, Xtro\armc4" "Mmus\Ctnnd2, Mmus\Pkp4, Mmus\Arvcf, Mmus\Armc3, Mmus\Armc4, Mmus\Ctnnb1, Mmus\Jup" "Hsap\PKP4, Hsap\CTNNB1, Hsap\ARMC3, Hsap\JUP, Hsap\CTNND2, Hsap\ARVCF" viable FBgn0043532 Obp56i Odorant-binding protein 56i http://flybase.org/reports/FBgn0043532 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush odorant binding ; GO:0005549 | inferred from sequence or structural similarity with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush sensory perception of smell ; GO:0007608 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with UniProtKB:P34174 extracellular space ; GO:0005615 | inferred from direct assay extracellular region ; GO:0005576 | inferred from sequence model "56i, 56I, Obp-a, anon-AE003794.2, CG30448, Obp56i, DmelObp56i" IPR006170:Pheromone/general odorant binding protein CG30448 27-Aug-18 DroID_v2018_08 - - - - - - "viable,body color defective" mesothoracic tergum FBgn0051925 CG31925 - http://flybase.org/reports/FBgn0051925 protein_coding_gene - - - CG31925 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0082924 snoRNA:Or-aca2 snoRNA:Or-aca2 http://flybase.org/reports/FBgn0082924 snoRNA_gene - - - "snoRNA:Or-aca2, Or_aca2 snoRNA, DmOr_aca2 snoRNA, DmOr_aca2, CR34593, Or-aca2, snoRNA:Or-ACA2" - CR34593 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032601 yellow-b yellow-b http://flybase.org/reports/FBgn0032601 protein_coding_gene - melanin biosynthetic process ; GO:0042438 | inferred from biological aspect of ancestor with PANTHER:PTN000000448 cuticle pigmentation ; GO:0048067 | inferred from biological aspect of ancestor with PANTHER:PTN000000448 - "CG17914, yellow-b, yell-b, Yellow-b" "IPR017996:Major royal jelly protein/protein yellow, IPR011042:Six-bladed beta-propeller, TolB-like" CG17914 27-Aug-18 DroID_v2018_08 Drer\dpm3 - "Cele\F49E11.8, Cele\T27A1.3, Cele\C24H12.1, Cele\fbxa-76" Xtro\dpm3 Mmus\Dpm3 Hsap\DPM3 " embryonic stage , pupal stage , adult stage , larval stage " adult head

viable FBgn0267572 asRNA:CR45912 - http://flybase.org/reports/FBgn0267572 non_protein_coding_gene - - - CR45912 - CR45912 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0010932 l(3)09070 lethal (3) 09070 http://flybase.org/reports/FBgn0010932 - gene - - - l(3)09070 - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0030087 CG7766 - http://flybase.org/reports/FBgn0030087 protein_coding_gene calmodulin binding ; GO:0005516 | inferred from electronic annotation with InterPro:IPR008734 phosphorylase kinase activity ; GO:0004689 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000844181 glycogen metabolic process ; GO:0005977 | inferred from electronic annotation with InterPro:IPR008734 phosphorylase kinase complex ; GO:0005964 | inferred from biological aspect of ancestor with PANTHER:PTN000844181 CG7766 "IPR008734:Phosphorylase kinase alpha/beta subunit, IPR008928:Six-hairpin glycosidase-like, IPR011613:Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family" CG7766 27-Aug-18 DroID_v2018_08 "Drer\phkb, Drer\phka2, Drer\phka1b, Drer\phka1a" - Cele\C14B9.8 "Xtro\phka2, Xtro\phkb, Xtro\LOC100498239" "Mmus\Phka1, Mmus\Phkb, Mmus\Phka2" "Hsap\PHKA1, Hsap\PHKB, Hsap\PHKA2" FBgn0032415 rho-6 rhomboid-6 http://flybase.org/reports/FBgn0032415 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN000532910 protein processing ; GO:0016485 | inferred from biological aspect of ancestor with PANTHER:PTN000532910 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN001117493 "rho-6, Rho-related [33C1], CG17212, rho 6, rho6" "IPR002610:Peptidase S54, rhomboid, IPR017213:Peptidase S54, rhomboid, metazoan, IPR022764:Peptidase S54, rhomboid domain" CG17212 27-Aug-18 DroID_v2018_08 "Drer\rhbdl3, Drer\rhbdl1, Drer\rhbdl2" - "Cele\rom-2, Cele\rom-3, Cele\rom-1" Xtro\rhbdl2 "Mmus\Rhbdl3, Mmus\Rhbdl2, Mmus\Rhbdf1, Mmus\Rhbdl1" "Hsap\RHBDL1, Hsap\RHBDF1, Hsap\RHBDL2, Hsap\RHBDL3" viable FBgn0043994 Su(rst)D207 Su(rst)D207 http://flybase.org/reports/FBgn0043994 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "D207, Su(rst)D207" - - 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0266966 lncRNA:CR45417 - http://flybase.org/reports/FBgn0266966 non_protein_coding_gene - - - CR45417 - CR45417 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005433 l(1)v3 lethal (1) v3 http://flybase.org/reports/FBgn0005433 - gene - - - "l(1)3, l(1)v3" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0016942 stich2 sticky ch2 http://flybase.org/reports/FBgn0016942 FBgn0011718 gene - peripheral nervous system development ; GO:0007422 | traceable author statement - "sticky ch1-2, sticky ch, stich2" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" chordotonal organ FBgn0259869 Su(Ste):CR42438 Su(Ste):CR42438 http://flybase.org/reports/FBgn0259869 non_protein_coding_gene - - - "Su(Ste):CR42438, CR42438" - CR42438 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002616 M(3)69E Minute (3) 69E http://flybase.org/reports/FBgn0002616 - gene - - - "M[33d30], M(3)h, M(3)h[y], M(3L)h, Mh, M(3)y, M(3)v, M(3)6, M(3)33j, M(3)33d, M(3)69E" - - 27-Aug-18 DroID_v2018_08 - - - - - - "Minute,dominant,visible,developmental rate defective,eye color defective" "macrochaeta,eye,wing,pigment cell,wing vein L2,posterior crossvein" FBgn0259406 C153 - http://flybase.org/reports/FBgn0259406 gene - - - C153 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing,wing margin" FBgn0025747 l(3)95Az lethal (3) 95Az http://flybase.org/reports/FBgn0025747 - gene - - - l(3)95Az - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0025791 Su(var)b601 Suppressor of variegation b601 http://flybase.org/reports/FBgn0025791 - gene - - - "Su-var(2)b601, Su(var)b601" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259166 CG42271 - http://flybase.org/reports/FBgn0259166 protein_coding_gene "phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity ; GO:0016316 | inferred from biological aspect of ancestor with PANTHER:PTN000257020" signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000257020 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000257020 "CG42271, CG33248, CG1846, CG33249, INPP4A, FBgn0259166" "IPR000008:C2 domain, IPR001849:Pleckstrin homology domain, IPR011993:PH domain-like" CG42271 27-Aug-18 DroID_v2018_08 "Drer\inpp4ab, Drer\inpp4aa, Drer\inpp4b" - Cele\R01H10.7 Xtro\inpp4a "Mmus\Inpp4b, Mmus\Inpp4a, Mmus\Prex2" "Hsap\INPP4A, Hsap\INPP4B, Hsap\PREX2" FBgn0040185 l(1)G0226 lethal (1) G0226 http://flybase.org/reports/FBgn0040185 gene - - - l(1)G0226 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" "wing,chaeta" FBgn0033981 Cyp6a21 Cyp6a21 http://flybase.org/reports/FBgn0033981 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN001209891" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "cyp6a21, 6a21, CG10247, Cyp6a21" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG10247 27-Aug-18 DroID_v2018_08 "Drer\cyp3a65, Drer\cyp3c1, Drer\cyp4v8, Drer\tbxas1, Drer\cyp4f3, Drer\cyp3c2, Drer\cyp4v7, Drer\cyp3c3, Drer\cyp4t8, Drer\cyp3c4" Scer\ERG11 "Cele\cyp-25A4, Cele\cyp-13A11, Cele\cyp-32A1, Cele\cyp-13B2, Cele\cyp-25A3, Cele\cyp-42A1, Cele\cyp-25A1, Cele\cyp-29A4, Cele\cyp-25A6, Cele\cyp-44A1, Cele\cyp-13A10, Cele\cyp-13A4, Cele\cyp-43A1, Cele\cyp-31A2, Cele\cyp-13A12, Cele\cyp-31A3, Cele\cyp-13A5, Cele\cyp-13A7, Cele\cyp-13A2, Cele\cyp-29A3, Cele\cyp-25A2, Cele\cyp-32B1, Cele\cyp-13A3, Cele\cyp-13A6, Cele\cyp-37B1, Cele\cyp-29A2, Cele\cyp-13A8, Cele\cyp-13A1, Cele\cyp-13B1" "Xtro\LOC100494419, Xtro\tbxas1, Xtro\cyp3a5, Xtro\cyp3a4" "Mmus\Cyp4f18, Mmus\Cyp4f37, Mmus\Cyp3a41a, Mmus\Cyp4a14, Mmus\Cyp3a44, Mmus\Cyp4f16, Mmus\Cyp4a31, Mmus\Cyp4a10, Mmus\Cyp3a11, Mmus\Cyp3a13, Mmus\Cyp3a41b, Mmus\Tbxas1, Mmus\Cyp3a57, Mmus\Cyp4b1, Mmus\Cyp3a59, Mmus\Cyp20a1, Mmus\Cyp4f39, Mmus\Cyp4v3, Mmus\Cyp4f13, Mmus\Cyp4a32, Mmus\Cyp4a12b, Mmus\Cyp3a25, Mmus\Cyp4a12a, Mmus\Cyp3a16, Mmus\Cyp4f14, Mmus\Cyp4f15" "Hsap\CYP4F8, Hsap\CYP3A43, Hsap\CYP3A7-CYP3A51P, Hsap\CYP4B1, Hsap\CYP4F12, Hsap\CYP3A4, Hsap\CYP4V2, Hsap\CYP3A7, Hsap\CYP4X1, Hsap\TBXAS1, Hsap\CYP3A5, Hsap\CYP4Z1, Hsap\CYP4F3, Hsap\CYP20A1, Hsap\CYP4F2, Hsap\CYP4A11, Hsap\CYP4F11, Hsap\CYP4F22, Hsap\CYP4A22" viable FBgn0037172 ND-B14.5AL NADH dehydrogenase (ubiquinone) B14.5 A subunit-like http://flybase.org/reports/FBgn0037172 protein_coding_gene NADH dehydrogenase (ubiquinone) activity ; GO:0008137 | inferred from electronic annotation with InterPro:IPR009947 "mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from biological aspect of ancestor with PANTHER:PTN000968153" mitochondrial respiratory chain complex I ; GO:0005747 | inferred from biological aspect of ancestor with PANTHER:PTN000968153 "CG6914, BcDNA:AT13913, N4AM, ND-B14.5AL" IPR009947:NADH:ubiquinone oxidoreductase subunit B14.5a CG6914 27-Aug-18 DroID_v2018_08 Drer\ndufa7 - Cele\F45H10.3 - Mmus\Ndufa7 Hsap\NDUFA7 viable FBgn0263505 lncRNA:CR43494 - http://flybase.org/reports/FBgn0263505 non_protein_coding_gene - - - CR43494 - CR43494 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034070 SP2353 SP2353 http://flybase.org/reports/FBgn0034070 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881 molecular_function ; GO:0003674 | no biological data available negative regulation of innate immune response ; GO:0045824 | inferred from mutant phenotype rhabdomere development ; GO:0042052 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype muscle cell cellular homeostasis ; GO:0046716 | inferred from mutant phenotype inferred from genetic interaction with Dg extracellular space ; GO:0005615 | inferred from sequence or structural similarity with eys "CT18665, CG8403, BcDNA:GH12319, SP2353" "IPR000742:EGF-like domain, IPR001791:Laminin G domain, IPR013032:EGF-like, conserved site, IPR013320:Concanavalin A-like lectin/glucanase domain, IPR001881:EGF-like calcium-binding domain" CG8403 27-Aug-18 DroID_v2018_08 "Drer\egflam, Drer\hspg2, Drer\lama4, Drer\sid4, Drer\LOC101884253, Drer\agrn" - "Cele\T19D12.6, Cele\agr-1, Cele\unc-52" "Xtro\LOC100491172, Xtro\egflam, Xtro\agrn, Xtro\hspg2" "Mmus\Hspg2, Mmus\Agrn, Mmus\Egflam" "Hsap\AGRN, Hsap\HSPG2, Hsap\EYS, Hsap\EGFLAM" viable FBgn0028157 l(3)S041919 lethal (3) S041919 http://flybase.org/reports/FBgn0028157 gene - - - "0419/19, l(3)S041919" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0038275 CG3817 - http://flybase.org/reports/FBgn0038275 protein_coding_gene - maturation of LSU-rRNA ; GO:0000470 | inferred from biological aspect of ancestor with PANTHER:PTN000326640 maturation of 5.8S rRNA ; GO:0000460 | inferred from biological aspect of ancestor with PANTHER:PTN000326640 neurogenesis ; GO:0022008 | inferred from mutant phenotype "preribosome, large subunit precursor ; GO:0030687 | inferred from biological aspect of ancestor with PANTHER:PTN000326640" "CG3817, RRP15" IPR012459:Ribosomal RNA-processing protein 15 CG3817 27-Aug-18 DroID_v2018_08 Drer\rrp15 Scer\RRP15 Cele\F53E10.6 - Mmus\Rrp15 Hsap\RRP15 "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC15515 K -0.016082646 0.032359987 0.455390794 -0.105585825 -1.899419552 0.385474073 FBgn0040484 BobD Brother of Brd D http://flybase.org/reports/FBgn0040484 gene - - - "Bob, BobD" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0020822 l(3)98Dh lethal (3) 98Dh http://flybase.org/reports/FBgn0020822 - gene - - - "M315, l(3)98Dh" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0020565 anon-EB8 anon-EB8 http://flybase.org/reports/FBgn0020565 - gene - - - anon-EB8 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033884 CG13344 - http://flybase.org/reports/FBgn0033884 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN001408403 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with MGI:MGI:1890215 protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with MGI:MGI:1890215 positive regulation of NF-kappaB transcription factor activity ; GO:0051092 | inferred from biological aspect of ancestor with PANTHER:PTN000324465 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001408403 "CG13344, anon-EST:GressD1, anon-EST:GreesD1" "IPR001841:Zinc finger, RING-type, IPR006575:RWD domain, IPR016135:Ubiquitin-conjugating enzyme/RWD-like, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG13344 27-Aug-18 DroID_v2018_08 Drer\rnf25 - Cele\Y53G8AR.5 Xtro\rnf25 Mmus\Rnf25 Hsap\RNF25 "viable,fertile,visible" "trichogen cell,mesothoracic tergum" FBgn0001539 l(1)14DEa lethal (1) 14DEa http://flybase.org/reports/FBgn0001539 - gene - - - l(1)14DEa - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0020387 Pdz Pdz http://flybase.org/reports/FBgn0020387 - gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available - Pdz - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263107 bft bereft http://flybase.org/reports/FBgn0263107 miRNA_gene molecular_function ; GO:0003674 | no biological data available chaeta morphogenesis ; GO:0008407 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype chaeta development ; GO:0022416 | inferred from mutant phenotype negative regulation of apoptotic process ; GO:0043066 | inferred from genetic interaction with hid gene silencing by miRNA ; GO:0035195 | inferred from direct assay cellular_component ; GO:0005575 | no biological data available "miR-263a, mir-263a, dme-mir-263a, 263a, bft, CR31863, CR42938, CR33580, miR-263, dme-miR-263a" - CR42938 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,partially,viable,recessive,visible,lethal - all die before end of P-stage,some die during pharate adult stage,fertile" "interommatidial bristle,orbital bristle,vertical bristle,postvertical bristle,humeral bristle,dorsocentral bristle,postalar bristle,scutellar bristle,eye,wing,wing margin bristle,interommatidial bristle & socket,sensillum trichodeum,sensillum trichodeum & trichogen cell" FBgn0065335 l(2)SH1856 lethal (2) SH1856 http://flybase.org/reports/FBgn0065335 gene - - - "l(2)SH1856, l(2)SH2 1856" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0084678 vto vertigo http://flybase.org/reports/FBgn0084678 gene - adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype - "O151, vto" - - 27-Aug-18 DroID_v2018_08 - - - - - - "locomotor behavior defective,recessive" FBgn0035610 Lkr Leucokinin receptor http://flybase.org/reports/FBgn0035610 protein_coding_gene neuropeptide Y receptor activity ; GO:0004983 | inferred from electronic annotation with InterPro:IPR000611 leucokinin receptor activity ; GO:0042071 | inferred from direct assay neuropeptide receptor activity ; GO:0008188 | inferred from sequence model "G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR000611 positive regulation of cytosolic calcium ion concentration ; GO:0007204 | inferred from direct assay G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model negative regulation of feeding behavior ; GO:2000252 | inferred from mutant phenotype" integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with TkR99D integral component of membrane ; GO:0016021 | inferred from sequence model basolateral plasma membrane ; GO:0016323 | inferred from direct assay "CG10626, DLKR, anon-WO0170980.119, anon-WO0170980.118, anon-WO0131005.17, Lkr, dLKR, LK-R, LkR, lkr, LKR" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR000611:Neuropeptide Y receptor family, IPR017452:GPCR, rhodopsin-like, 7TM" CG10626 27-Aug-18 DroID_v2018_08 "Drer\tacr1b, Drer\prokr1a, Drer\npffr1l1, Drer\tacr2, Drer\prlhr2b, Drer\prlhr2a, Drer\tacr3a, Drer\npffr2a, Drer\npffr1l2, Drer\tacr3l, Drer\prokr1b, Drer\LOC100333270, Drer\tacr1a" - "Cele\tkr-1, Cele\npr-22, Cele\tkr-3, Cele\K01A12.3, Cele\gtr-1" "Xtro\prokr1, Xtro\tacr1, Xtro\prokr2, Xtro\tacr3, Xtro\LOC100493271, Xtro\LOC100497124" "Mmus\Tacr2, Mmus\Prokr1, Mmus\Prokr2, Mmus\Pgr15l, Mmus\Tacr1, Mmus\Tacr3, Mmus\Npy1r" "Hsap\TACR3, Hsap\PROKR1, Hsap\TACR2, Hsap\NPY1R, Hsap\TACR1" viable FBgn0266735 asRNA:CR45208 - http://flybase.org/reports/FBgn0266735 non_protein_coding_gene - - - CR45208 - CR45208 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0017483 Sxl::w Sxl::w http://flybase.org/reports/FBgn0017483 - engineered_fusion_gene - - - Sxl::w - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002927 Ndw Nicked wing http://flybase.org/reports/FBgn0002927 - gene - - - Ndw - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,dominant,cold sensitive,lethal,recessive" FBgn0085324 CG34295 - http://flybase.org/reports/FBgn0085324 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254 - CG34295 "IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan" CG34295 27-Aug-18 DroID_v2018_08 - - - Xtro\tpsg1 Mmus\Prss27 Hsap\TMPRSS11B FBgn0267117 lncRNA:CR45557 - http://flybase.org/reports/FBgn0267117 non_protein_coding_gene - - - CR45557 - CR45557 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0020795 oculus-parvus oculus parvus http://flybase.org/reports/FBgn0020795 - gene - - - "opa, oculus-parvus" - - 27-Aug-18 DroID_v2018_08 - - - - - - eye FBgn0004965 coq coquilled http://flybase.org/reports/FBgn0004965 - gene molecular_function ; GO:0003674 | no biological data available imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available coq - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,maternal effect,some die during immature adult stage" "wing,ovary,maternal effect,egg" FBgn0000200 bly bellyache http://flybase.org/reports/FBgn0000200 - gene molecular_function ; GO:0003674 | no biological data available Malpighian tubule morphogenesis ; GO:0007443 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available bly - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "embryonic Malpighian tubule,embryonic/larval midgut" FBgn0262815 CR43186 - http://flybase.org/reports/FBgn0262815 pseudogene_attribute - - - "CG43186, CR43186, DMG6-MB6.chr2R.20.008" - CR43186 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005117 l(1)FMa lethal (1) FMa http://flybase.org/reports/FBgn0005117 - gene - - - "l(1)69a, l(1)FMa" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0086373 EP3916 - http://flybase.org/reports/FBgn0086373 gene - - - EP3916 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0028841 jhamt juvenile hormone acid methyltransferase http://flybase.org/reports/FBgn0028841 protein_coding_gene juvenile hormone acid methyltransferase activity ; GO:0035049 | inferred from direct assay farnesoic acid O-methyltransferase activity ; GO:0019010 | inferred from direct assay juvenile hormone biosynthetic process ; GO:0006718 | inferred from mutant phenotype male courtship behavior ; GO:0008049 | inferred from mutant phenotype juvenile hormone biosynthetic process ; GO:0006718 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000010478 "CG17330, DmJHAMT, BG:DS09218.5, JAHMT, jhamt, JHAMT, JHamt, Jhamt" "IPR013217:Methyltransferase type 12, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG17330 27-Aug-18 DroID_v2018_08 - - - - - - "developmental rate defective,lethal - all die before end of P-stage,some die during pharate adult stage,wild-type,viable" male genitalia FBgn0004209 l(3)84Eg lethal (3) 84Eg http://flybase.org/reports/FBgn0004209 - gene - - - l(3)84Eg - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0002801 ms(1)19E male sterile (1) 19E http://flybase.org/reports/FBgn0002801 - gene - - - "ms(1)E, ms(1)19E" - - 27-Aug-18 DroID_v2018_08 - - - - - - male sterile FBgn0260611 2L1794 - http://flybase.org/reports/FBgn0260611 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L1794 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0041594 l(3)10 lethal (3) 10 http://flybase.org/reports/FBgn0041594 gene - - - l(3)10 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0062681 EP1595 EP1595 http://flybase.org/reports/FBgn0062681 gene - - - "EP(X)1595, EP1595" - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,lethal" eye FBgn0038439 Cad89D Cadherin 89D http://flybase.org/reports/FBgn0038439 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002126, InterPro:IPR015919 calcium ion binding ; GO:0005509 | inferred from sequence model" homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from electronic annotation with InterPro:IPR002126 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0016339 | inferred from sequence or structural similarity cell-cell adhesion mediated by cadherin ; GO:0044331 | inferred from sequence model plasma membrane ; GO:0005886 | inferred from electronic annotation with InterPro:IPR020894 integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity "DCad89D, CG14900, CT34724, Cad89D" "IPR002126:Cadherin, IPR015919:Cadherin-like, IPR020894:Cadherin conserved site" CG14900 27-Aug-18 DroID_v2018_08 "Drer\cdhr5b, Drer\cdh16, Drer\cdh17, Drer\cdhr2, Drer\pcdh7a, Drer\cdh13, Drer\cdhr5a" - "Cele\cdh-8, Cele\cdh-3" - "Mmus\Pcdh7, Mmus\Pcdhb16, Mmus\Pcdhb15, Mmus\Pcdhb19, Mmus\Cdh13, Mmus\Cdhr2, Mmus\Cdh17, Mmus\Pcdhb21, Mmus\Pcdhb13, Mmus\Pcdhb10, Mmus\Pcdhb11, Mmus\Cdhr5" "Hsap\CDH13, Hsap\PCDHB5, Hsap\PCDHB16, Hsap\PCDHB10, Hsap\CDHR2, Hsap\CDHR5, Hsap\DCHS2, Hsap\CDH17" "viable,fertile,body color defective" mesothoracic tergum FBgn0040036 CG12550 - http://flybase.org/reports/FBgn0040036 protein_coding_gene - - - CG12550 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263745 CR43670 - http://flybase.org/reports/FBgn0263745 pseudogene_attribute - - - "CR43670, CG31782, BcDNA:GM06363" - CR43670 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0000969 fs(2)eo5 female sterile (2) eo5 http://flybase.org/reports/FBgn0000969 - gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "wp19, fs(2)eoWP19, fs(2)eo-G, fs(2)eo5" - - 27-Aug-18 DroID_v2018_08 - - - - - - female sterile FBgn0083311 E(smoDN)1414 Enhancer of smoDN 1414 http://flybase.org/reports/FBgn0083311 gene - - - E(smoDN)1414 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002406 l(3)99Dg lethal (3) 99Dg http://flybase.org/reports/FBgn0002406 - gene - - - l(3)99Dg - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0060925 l(3)S042205 lethal (3) S042205 http://flybase.org/reports/FBgn0060925 gene - - - "0422/05, l(3)S042205" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0060522 l(3)S102312b lethal (3) S102312b http://flybase.org/reports/FBgn0060522 gene - - - "1023/12, l(3)S102312b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0061497 l(2)45Ap lethal (2) 45Ap http://flybase.org/reports/FBgn0061497 gene - - - l(2)45Ap - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0266171 pre-mod(mdg4)-AB - http://flybase.org/reports/FBgn0266171 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "pre-mod(mdg4)-AB, CG44877" "IPR007588:Zinc finger, FLYWCH-type" CG44877 27-Aug-18 DroID_v2018_08 - - - - "Mmus\Flywch2, Mmus\Flywch1" - FBgn0262765 Mst77Y-17Psi Male-specific pseudogene 77Y 17 http://flybase.org/reports/FBgn0262765 pseudogene_attribute - - - Mst77Y-17Psi - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0020811 mei-1223 mei-1223 http://flybase.org/reports/FBgn0020811 - gene - - - mei-1223 - - 27-Aug-18 DroID_v2018_08 - - - - - - "meiotic cell cycle defective,male" spermatid FBgn0266693 lncRNA:CR45183 - http://flybase.org/reports/FBgn0266693 non_protein_coding_gene - - - CR45183 - CR45183 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001833 l(1)ts504 lethal (1) ts504 http://flybase.org/reports/FBgn0001833 - gene - - - l(1)ts504 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,heat sensitive,some die during pupal stage" "adult head,adult thorax" FBgn0040588 CG13841 - http://flybase.org/reports/FBgn0040588 protein_coding_gene - - - CG13841 - CG13841 27-Aug-18 DroID_v2018_08 - - - - - - DRSC26257 K -0.710219897 -0.906539037 0.246235043 -0.343377375 -0.079942826 1.752175511 FBgn0265699 lncRNA:CR44506 - http://flybase.org/reports/FBgn0265699 non_protein_coding_gene - - - CR44506 - CR44506 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0053491 CR33491 - http://flybase.org/reports/FBgn0053491 pseudogene_attribute - - - "CG33491, CR33491" - CR33491 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264325 Atg6 Autophagy-related 6 http://flybase.org/reports/FBgn0264325 protein_coding_gene molecular_function ; GO:0003674 | no biological data available autophagy ; GO:0006914 | inferred from mutant phenotype salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern autophagosome assembly ; GO:0000045 | inferred from biological aspect of ancestor with PANTHER:PTN000298965 late endosome to vacuole transport ; GO:0045324 | inferred from biological aspect of ancestor with PANTHER:PTN000298965 larval midgut cell programmed cell death ; GO:0035096 | inferred from mutant phenotype cellular response to nitrogen starvation ; GO:0006995 | inferred from biological aspect of ancestor with PANTHER:PTN000298965 defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype endocytosis ; GO:0006897 | inferred from mutant phenotype autophagy ; GO:0006914 | inferred from mutant phenotype inferred from genetic interaction with Pi3K59F hemopoiesis ; GO:0030097 | inferred from mutant phenotype glycophagy ; GO:0061723 | inferred from mutant phenotype negative regulation of innate immune response ; GO:0045824 | inferred from mutant phenotype neuron remodeling ; GO:0016322 | inferred from mutant phenotype response to oxidative stress ; GO:0006979 | inferred from mutant phenotype inferred from genetic interaction with puc nucleophagy ; GO:0044804 | inferred from biological aspect of ancestor with PANTHER:PTN000298965 protein secretion ; GO:0009306 | inferred from mutant phenotype autophagic cell death ; GO:0048102 | inferred from expression pattern cellular response to starvation ; GO:0009267 | inferred from mutant phenotype "phosphatidylinositol 3-kinase complex, class III, type I ; GO:0034271 | inferred from direct assay pre-autophagosomal structure ; GO:0000407 | inferred from biological aspect of ancestor with PANTHER:PTN000298965 cytoplasmic vesicle ; GO:0031410 | inferred from biological aspect of ancestor with PANTHER:PTN000298965 phosphatidylinositol 3-kinase complex, class III, type II ; GO:0034272 | inferred from biological aspect of ancestor with PANTHER:PTN000298965" "Atg6, CG5429, l(3)00096, atg6, Beclin-1, DmAtg6, ATG6, Beclin1, beclin, dAtg6" IPR007243:Atg6/Beclin CG5429 27-Aug-18 DroID_v2018_08 Drer\becn1 Scer\VPS30 Cele\bec-1 Xtro\becn1 "Mmus\Becn2, Mmus\Becn1" "Hsap\BECN1, Hsap\BECN2" FBgn0026141 Cdlc2 Cytoplasmic dynein light chain 2 http://flybase.org/reports/FBgn0026141 FBgn0044766 protein_coding_gene "ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity" "microtubule-based process ; GO:0007017 | inferred from electronic annotation with InterPro:IPR001372, InterPro:IPR019763 microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity" dynein complex ; GO:0030286 | inferred from electronic annotation with InterPro:IPR001372 dynein complex ; GO:0030286 | inferred from sequence or structural similarity "CG5450, dlc, anon-WO0140519.117, Cdlc2, Cdcl2" "IPR001372:Dynein light chain, type 1/2, IPR019763:Dynein light chain, type 1/2, conserved site" CG5450 27-Aug-18 DroID_v2018_08 "Drer\dnal4b, Drer\dynll2b, Drer\dynll1, Drer\dnal4a, Drer\dynll2a" Scer\DYN2 "Cele\dlc-1, Cele\dlc-2, Cele\dlc-5" "Xtro\dynll1, Xtro\dynll2, Xtro\dnal4" "Mmus\BC048507, Mmus\Dynll2, Mmus\Dnal4, Mmus\Dynll1" "Hsap\DYNLL2, Hsap\DYNLL1, Hsap\DNAL4" "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0034128 CG4409 - http://flybase.org/reports/FBgn0034128 protein_coding_gene - - - CG4409 IPR010629:Insect allergen-related CG4409 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0001195 His1 Histone H1 http://flybase.org/reports/FBgn0001195 - protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819" "negative regulation of histone modification ; GO:0031057 | inferred from direct assay chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromosome organization ; GO:0051276 | inferred from mutant phenotype nucleosome assembly ; GO:0006334 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819" "nucleosome ; GO:0000786 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819 nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR005818 condensed nuclear chromosome ; GO:0000794 |" "H1, HisC, H1A, hisl, DmeH1, His1, histone, his, dH1" "IPR005818:Linker histone H1/H5, domain H15, IPR005819:Histone H5, IPR011991:Winged helix-turn-helix DNA-binding domain" - 27-Aug-18 DroID_v2018_08 - - - - - - lethal "polytene chromosomeda.G32,polytene chromosome chromocenterda.G32" FBgn0013584 l(3)92Ea lethal (3) 92Ea http://flybase.org/reports/FBgn0013584 - gene - - - "AS416, l(3)92Ea" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0040089 meso18E meso18E http://flybase.org/reports/FBgn0040089 protein_coding_gene - mesoderm development ; GO:0007498 | inferred from expression pattern - "Meso18E, ld26007, Dmeso18E, Mmeso18E, eso18E, anon-18DEd, CG14233, meso18E" - CG14233 27-Aug-18 DroID_v2018_08 Drer\si:ch211-116o3.5 - - - - - "viable,fertile" FBgn0263738 Ada2a transcriptional Adaptor 2a http://flybase.org/reports/FBgn0263738 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR009057 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN000271860 transcription coactivator activity ; GO:0003713 | inferred from biological aspect of ancestor with PANTHER:PTN000271860 histone acetyltransferase activity ; GO:0004402 | contributes_to inferred from direct assay chromatin binding ; GO:0003682 | inferred from biological aspect of ancestor with PANTHER:PTN000271860" histone H4 acetylation ; GO:0043967 | inferred from direct assay positive regulation of histone acetylation ; GO:0035066 | inferred from biological aspect of ancestor with PANTHER:PTN000271860 histone acetylation ; GO:0016573 | inferred from direct assay histone H3 acetylation ; GO:0043966 | inferred from direct assay regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN000271860 chromatin remodeling ; GO:0006338 | inferred from direct assay SAGA-type complex ; GO:0070461 | inferred from biological aspect of ancestor with PANTHER:PTN000271862 transcriptionally active chromatin ; GO:0035327 | inferred from direct assay Ada2/Gcn5/Ada3 transcription activator complex ; GO:0005671 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG43663, dAda2a, Ada2a, Ada2A, CG7150, CG31318, CG33520, dAda2A, ada2a, ADA2a, dADA2a, DmADA2a, DmAda2a" "IPR016827:Transcriptional adaptor 2, IPR009057:Homeobox domain-like, IPR007526:SWIRM domain, IPR011991:Winged helix-turn-helix DNA-binding domain" CG43663 27-Aug-18 DroID_v2018_08 "Drer\tada2b, Drer\tada2a, Drer\polr2d" "Scer\YOR338W, Scer\ADA2, Scer\FUN19, Scer\RPB4" "Cele\ada-2, Cele\rpb-4" "Xtro\tada2a, Xtro\polr2d, Xtro\tada2b" "Mmus\Tada2b, Mmus\Polr2d, Mmus\Tada2a" "Hsap\TADA2A, Hsap\POLR2D, Hsap\TADA2B" "lethal - all die before end of first instar larval stage,some die during first instar larval stage,viable,lethal" FBgn0010772 Xe7 Xe7 http://flybase.org/reports/FBgn0010772 FBgn0037362 protein_coding_gene molecular_function ; GO:0003674 | no biological data available axon guidance ; GO:0007411 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "l(3)02248, CG2179, Xe7" - CG2179 27-Aug-18 DroID_v2018_08 Drer\akap17a - Cele\cux-7 Xtro\akap17a Mmus\Akap17b Hsap\AKAP17A "lethal,neuroanatomy defective,somatic clone,recessive,viable,visible" "chaeta,supernumerary" FBgn0029502 COQ7 COQ7 http://flybase.org/reports/FBgn0029502 protein_coding_gene - oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR011566 ubiquinone biosynthetic process ; GO:0006744 | inferred from electronic annotation with InterPro:IPR011566 - "Dclk1, CG14437, COQ7" "IPR009078:Ferritin-like superfamily, IPR011566:Ubiquinone biosynthesis protein Coq7, IPR012347:Ferritin-related" CG14437 27-Aug-18 DroID_v2018_08 Drer\coq7 Scer\CAT5 Cele\clk-1 Xtro\coq7 Mmus\Coq7 Hsap\COQ7 "developmental rate defective,RU486 conditional,short lived,female,viable" FBgn0011981 tRNA:Ser-AGA-3-2 transfer RNA:Serine-AGA 3-2 http://flybase.org/reports/FBgn0011981 "FBgn0003830, FBgn0011968, FBgn0052618, FBgn0060070" tRNA_gene UCU codon-amino acid adaptor activity ; GO:0033405 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033405 cytosol ; GO:0005829 | inferred by curator from GO:0033405 "774-2, Ser-tRNA-4-7, AE002593.trna9-SerAGA, tRNA:S:AGA:AE002593-b, CR32618, tRNA:ser, tRNA:S, tRNA:ser774:12Ef, tRNA[[Ser]], chrX.trna13-SerAGA, tRNA-Ser-AGA-3-2, tRNA:Ser-AGA-3-2, tRNA:S774:12Ef, UCU" - CR32618 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0014113 anon-84Bb anon-84Bb http://flybase.org/reports/FBgn0014113 - gene - - - "Y3, anon-84Bb" - - 27-Aug-18 DroID_v2018_08 - - - - - - " embryonic stage&&larval stage&&pupal stage , adult stage && oogenesis stage " unfertilized egg

FBgn0001919 l(2)25Bf lethal (2) 25Bf http://flybase.org/reports/FBgn0001919 - gene - - - "jf15, l(2)jf15, l(2)25Bf" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0003916 snRNA:U1:21D small nuclear RNA U1 at 21D http://flybase.org/reports/FBgn0003916 "FBgn0003915, FBgn0026794, FBgn0051656" snRNA_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity" U1 snRNP ; GO:0005685 | inferred from sequence or structural similarity "snRNA:U1, U1, U1 snRNA, U1a-21D, U1a1(AT)[[15]], U1-21.1, U1snRNA, U1a, U1-1, U1 21D, U14, K5, dU1, snRNA1, snRNA-U1-21.1, U1snRNA21D, CR31656, snRNA:U1:21D, U1:21D, U1-21D, 21E U1" - CR31656 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0052553 lncRNA:CR32553 - http://flybase.org/reports/FBgn0052553 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG32553, CR32553" - CR32553 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259821 CG42402 - http://flybase.org/reports/FBgn0259821 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from electronic annotation with InterPro:IPR000922 - - "CG42402, CG12453, CG41358" IPR000922:D-galactoside/L-rhamnose binding SUEL lectin domain CG42402 27-Aug-18 DroID_v2018_08 "Drer\zgc:153499, Drer\si:dkeyp-46h3.2, Drer\si:ch211-66i15.5, Drer\si:dkeyp-46h3.8, Drer\si:dkey-90l23.1, Drer\eva1c, Drer\LOC564755, Drer\zgc:136410, Drer\zgc:171776, Drer\LOC100536038, Drer\si:ch73-335m24.2, Drer\si:ch1073-75o15.3, Drer\si:ch1073-75o15.4, Drer\LOC101882949, Drer\si:ch211-145c1.1" - Cele\eva-1 Xtro\eva1c Mmus\Eva1c Hsap\EVA1C viable FBgn0086303 proj projectile http://flybase.org/reports/FBgn0086303 gene - filopodium assembly ; GO:0046847 | inferred from mutant phenotype - proj - - 27-Aug-18 DroID_v2018_08 - - - - - - "neuroanatomy defective,lethal,recessive" dendrite & filopodium & larva FBgn0266101 CG44838 - http://flybase.org/reports/FBgn0266101 protein_coding_gene - - - "CG44838, CG32043, CG18632, CG3628, anon-WO0118547.427, anon-WO0118547.368, CG14180" IPR015943:WD40/YVTN repeat-like-containing domain CG44838 27-Aug-18 DroID_v2018_08 Drer\ostf1 - Cele\Y106G6H.14 - Mmus\Ostf1 Hsap\OSTF1 DRSC10179 EK -0.71726897 -1.492336756 0.314343695 -1.558680022 1.658581272 0.790585339 FBgn0266486 CG45085 - http://flybase.org/reports/FBgn0266486 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG45085, Dromel_CG8026_FBtr0088611_uORF" - CG45085 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034114 CG4282 - http://flybase.org/reports/FBgn0034114 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG4282 "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type" CG4282 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-30k6.5, Drer\prdm10, Drer\zgc:153116, Drer\prdm5" - "Cele\ZK686.5, Cele\H16D19.3, Cele\lsy-2, Cele\Y37F4.6, Cele\T20H4.2, Cele\Y55F3AM.14, Cele\T07D10.3" "Xtro\znf142, Xtro\prdm5" "Mmus\Prdm10, Mmus\Zfp386, Mmus\Zfy1, Mmus\Zfy2" "Hsap\ZNF521, Hsap\PRDM5, Hsap\PRDM10, Hsap\ZNF805, Hsap\PRDM15, Hsap\ZNF100" viable FBgn0032331 CG14913 - http://flybase.org/reports/FBgn0032331 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from sequence model CG14913 - CG14913 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0011865 tRNA:Gly-GCC-1-7 transfer RNA:Glycine-GCC 1-7 http://flybase.org/reports/FBgn0011865 "FBgn0003779, FBgn0051981, FBgn0060221" tRNA_gene GGC codon-amino acid adaptor activity ; GO:0033462 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033462 cytosol ; GO:0005829 | inferred by curator from GO:0033462 "BG:DS04641.6, AE002690.trna16-GlyGCC, tRNA:G:GCC:AE002690-d, CR31981, tRNA:gly3:35Bd, tRNA[Gly-GCC], chr2L.trna25-GlyGCC, tRNA-Gly-GCC-1-7, tRNA:Gly-GCC-1-7, tRNA:G3:35Bd, GGC" - CR31981 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001570 l(1)20Cb lethal (1) 20Cb http://flybase.org/reports/FBgn0001570 - gene - - - "l(1)Q463, l(1)20, Q463, 20, lQ463, l20, l(1)20Cb" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,cell lethal,germline clone,lethal - all die before end of larval stage,some die during larval stage,polyphasic" FBgn0265741 lncRNA:CR44548 - http://flybase.org/reports/FBgn0265741 non_protein_coding_gene - - - "CR44548, lincRNA.515" - CR44548 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030480 Tim9a Tim9a http://flybase.org/reports/FBgn0030480 protein_coding_gene P-P-bond-hydrolysis-driven protein transmembrane transporter activity ; GO:0015450 | inferred from sequence or structural similarity with UniProtKB:Q9Y5J7 protein targeting to mitochondrion ; GO:0006626 | inferred from sequence or structural similarity with UniProtKB:Q9Y5J7 mitochondrial inner membrane presequence translocase complex ; GO:0005744 | inferred from sequence or structural similarity with UniProtKB:Q9Y5J7 "Tim9, CG1660, Tim9a" IPR004217:Tim10/DDP family zinc finger CG1660 27-Aug-18 DroID_v2018_08 "Drer\timm9, Drer\timm10b" Scer\TIM9 "Cele\tin-9.1, Cele\tin-9.2" Xtro\timm9 "Mmus\Timm9, Mmus\Timm10b" "Hsap\TIMM9, Hsap\TIMM10B" "lethal,recessive,viable" FBgn0001729 l(1)ESHS50 lethal (1) ESHS50 http://flybase.org/reports/FBgn0001729 - gene - - - l(1)ESHS50 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0065976 iab4-5.as iab4-5.as http://flybase.org/reports/FBgn0065976 gene - - - "4-5 as, iab4-5.as" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0053929 CR33929 - http://flybase.org/reports/FBgn0053929 pseudogene_attribute - - - "CR33929, CG33929" - CR33929 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065803 l(2)SH0400 lethal (2) SH0400 http://flybase.org/reports/FBgn0065803 gene - - - "l(2)SH0400, l(2)SH2 0400" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0036950 CG6996 - http://flybase.org/reports/FBgn0036950 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG6996 IPR002557:Chitin binding domain CG6996 27-Aug-18 DroID_v2018_08 Drer\thbd - "Cele\C39D10.7, Cele\R02F2.4, Cele\cpg-2, Cele\cpg-1" - - Hsap\MATN2 viable FBgn0000584 Erect Erect http://flybase.org/reports/FBgn0000584 - gene - - - "Erect, Er" - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "posterior scutellar bristle,wing" FBgn0035989 CG3967 - http://flybase.org/reports/FBgn0035989 protein_coding_gene tubulin N-acetyltransferase activity ; GO:0019799 | inferred from biological aspect of ancestor with PANTHER:PTN000269078 alpha-tubulin acetylation ; GO:0071929 | inferred from biological aspect of ancestor with PANTHER:PTN000269078 behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype regulation of microtubule cytoskeleton organization ; GO:0070507 | inferred from biological aspect of ancestor with PANTHER:PTN000269078 microtubule ; GO:0005874 | inferred from electronic annotation with InterPro:IPR007965 CG3967 "IPR007965:Gcn5-related N-acetyltransferase (GNAT) domain, ATAT-type" CG3967 27-Aug-18 DroID_v2018_08 Drer\atat1 - "Cele\mec-17, Cele\atat-2" Xtro\atat1 Mmus\Atat1 Hsap\ATAT1 "learning defective,hyperactive,conditional,chemical resistant,viable" FBgn0082630 S(CycE[JP])2.8 S(CycE[JP])2.8 http://flybase.org/reports/FBgn0082630 gene - - - S(CycE[JP])2.8 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0033680 CG13186 - http://flybase.org/reports/FBgn0033680 protein_coding_gene - - - "AAF58585, BcDNA:AT11581, CG13186" - CG13186 27-Aug-18 DroID_v2018_08 Drer\cenpa - - - Mmus\Selenoh Hsap\SELENOH FBgn0011295 CG11297 - http://flybase.org/reports/FBgn0011295 - protein_coding_gene - - - "P28, anon2L, anon-2L, anon-21DEa, CG11297" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0003869 tta tetanic http://flybase.org/reports/FBgn0003869 - gene - - - tta - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,heat sensitive,female sterile,behavior defective" "wing,neck,abdomen,proboscis" FBgn0034737 CG11362 - http://flybase.org/reports/FBgn0034737 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG11362 - CG11362 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0262822 lncRNA:CR43193 - http://flybase.org/reports/FBgn0262822 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43193, CR43193, mdcds_58258" - CR43193 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266314 lncRNA:CR44979 - http://flybase.org/reports/FBgn0266314 non_protein_coding_gene - - - CR44979 - CR44979 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065375 l(2)SH1683 lethal (2) SH1683 http://flybase.org/reports/FBgn0065375 gene - - - "l(2)SH1683, l(2)SH2 1683" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0265609 asRNA:CR44427 - http://flybase.org/reports/FBgn0265609 non_protein_coding_gene - - - CR44427 - CR44427 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039319 CG13659 - http://flybase.org/reports/FBgn0039319 protein_coding_gene - - - CG13659 "IPR015897:CHK kinase-like, IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain" CG13659 27-Aug-18 DroID_v2018_08 - - "Cele\D1044.1, Cele\C29F7.2, Cele\C29F7.1, Cele\dhs-27, Cele\H06H21.8, Cele\nhr-246" - - - "viable,fertile" FBgn0021772 ms(3)P122 ms(3)P122 http://flybase.org/reports/FBgn0021772 - gene - - - ms(3)P122 - - 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,recessive" FBgn0263982 CG43731 - http://flybase.org/reports/FBgn0263982 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43731 - CG43731 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0011210 shk shank http://flybase.org/reports/FBgn0011210 - gene - male meiosis ; GO:0007140 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype - "ms(3)07735, shk" - - 27-Aug-18 DroID_v2018_08 - - - - - - "meiotic cell cycle defective,male sterile,recessive" "spermatid,Nebenkern" FBgn0014155 e(w[a])r "enhancer of white-apricot, recessive" http://flybase.org/reports/FBgn0014155 - gene - - - "e(w[a])r, e(w[a])" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0015879 anon-48Ah anon-48Ah http://flybase.org/reports/FBgn0015879 - gene - - - "X, anon-48Ah" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0014204 l(1)16Fk lethal (1) 16Fk http://flybase.org/reports/FBgn0014204 - gene - - - "HL-XIII, l(1)16Fk" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0001766 l(1)M26 lethal (1) M26 http://flybase.org/reports/FBgn0001766 - gene - - - l(1)M26 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0029724 CG15472 - http://flybase.org/reports/FBgn0029724 protein_coding_gene - - - CG15472 IPR031732:Protein of unknown function DUF4729 CG15472 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0030136 RpS28b Ribosomal protein S28b http://flybase.org/reports/FBgn0030136 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000080571 structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with SGD:S000005693 translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR000289 cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022627 maturation of SSU-rRNA ; GO:0030490 | inferred from biological aspect of ancestor with PANTHER:PTN000080571 ribosomal small subunit assembly ; GO:0000028 | inferred from biological aspect of ancestor with PANTHER:PTN000080571 cytoplasmic translation ; GO:0002181 | traceable author statement cytosolic small ribosomal subunit ; GO:0022627 | inferred from sequence or structural similarity with SGD:S000005693 cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement "RpS28b, CG2998, RS28_DROME" "IPR000289:Ribosomal protein S28e, IPR012340:Nucleic acid-binding, OB-fold, IPR028626:Ribosomal protein S28e conserved site" CG2998 27-Aug-18 DroID_v2018_08 Drer\rps28 "Scer\RPS28B, Scer\RPS28A" Cele\rps-28 Xtro\rps28p9 Mmus\Rps28 Hsap\RPS28 lethal DRSC18258 EK -0.142827143 -1.045384294 0.280846002 -1.758446591 1.554184109 3.1699096 FBgn0267493 Mst77Y-9 Male-specific transcript 77Y 9 http://flybase.org/reports/FBgn0267493 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "spermatogenesis, exchange of chromosomal proteins ; GO:0035093 | inferred from sequence or structural similarity with Mst77F" chromatin ; GO:0000785 | inferred from sequence or structural similarity with Mst77F "Mst77Y-9, CG45769, MST77Y" - CG45769 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0021433 Dl::Ser Dl::Ser http://flybase.org/reports/FBgn0021433 - engineered_fusion_gene - - - Dl::Ser - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,neuroanatomy defective" "macrochaeta & thorax | supernumerary-537.4,ommatidium & eye disch-H10,photoreceptor cell R8 & eye disch-H10,macrochaeta & thorax | supernumerary | somatic clone | cell autonomousUbx.PdC,eye" FBgn0028050 l(3)S096108 lethal (3) S096108 http://flybase.org/reports/FBgn0028050 gene - - - "0961/08, l(3)S096108" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0064171 l(3)201.51 lethal (3) 201.51 http://flybase.org/reports/FBgn0064171 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available l(3)201.51 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0003539 Str Stretched wings http://flybase.org/reports/FBgn0003539 - gene - - - Str - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" wing FBgn0016029 l(3)89El lethal (3) 89El http://flybase.org/reports/FBgn0016029 - gene - - - "l(3)M171, l(3)89El" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0263536 mir-4974 mir-4974 stem loop http://flybase.org/reports/FBgn0263536 miRNA_gene - - - "mir-4974, dme-mir-4974, CR43521" - CR43521 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263964 BG01976 - http://flybase.org/reports/FBgn0263964 gene - - - BG01976 - - 27-Aug-18 DroID_v2018_08 - - - - - - "long lived,female limited,short lived,male limited,starvation stress response defective,temperature response defective,gravitaxis defective" FBgn0065752 l(2)SH0496 lethal (2) SH0496 http://flybase.org/reports/FBgn0065752 gene - - - "l(2)SH0496, l(2)SH2 0496" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0052334 CG32334 - http://flybase.org/reports/FBgn0052334 protein_coding_gene - - - CG32334 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0035254 CG7974 - http://flybase.org/reports/FBgn0035254 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available nucleoplasm ; GO:0005654 | inferred from sequence or structural similarity with HGNC:24932 CG7974 IPR010756:Hepatocellular carcinoma-associated antigen 59 CG7974 27-Aug-18 DroID_v2018_08 Drer\zgc:103692 - "Cele\T23G11.4, Cele\M151.4" Xtro\c9orf78 Mmus\BC005624 Hsap\C9orf78 viable FBgn0039688 Kul Kuzbanian-like http://flybase.org/reports/FBgn0039688 protein_coding_gene metalloendopeptidase activity ; GO:0004222 | inferred from direct assay membrane protein ectodomain proteolysis ; GO:0006509 | inferred from sequence or structural similarity with HGNC:195 regulation of Notch signaling pathway ; GO:0008593 | inferred from mutant phenotype membrane protein ectodomain proteolysis ; GO:0006509 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with HGNC:195 "ADAM10, CT3146, CG1964, Kul, kul" "IPR001590:Peptidase M12B, ADAM/reprolysin, IPR001762:Disintegrin domain, IPR024079:Metallopeptidase, catalytic domain, IPR034025:ADAM10/ADAM17 catalytic domain, IPR002870:Peptidase M12B, propeptide" CG1964 27-Aug-18 DroID_v2018_08 "Drer\si:ch1073-396h14.1, Drer\adam10a, Drer\adam17a, Drer\adam10b, Drer\adam17b" - Cele\sup-17 "Xtro\adam17, Xtro\adam10" "Mmus\Adam17, Mmus\Adam10" "Hsap\ADAM10, Hsap\ADAM17" "visible,partially lethal - majority die,some die during pupal stage" "wing,wing margin,wing vein,wing hair,supernumerary,interfollicle cell,trichogen cell,mesothoracic tergum" FBgn0036911 Fibp Fibp http://flybase.org/reports/FBgn0036911 protein_coding_gene fibroblast growth factor binding ; GO:0017134 | inferred from electronic annotation with InterPro:IPR008614 - - "CG8660, DrFIBP, Fibp, F1bp" IPR008614:Acidic fibroblast growth factor intracellular-binding protein CG8660 27-Aug-18 DroID_v2018_08 "Drer\fibpa, Drer\fibpb" - Cele\fbxa-135 Xtro\fibp Mmus\Fibp Hsap\FIBP "viable,fertile" FBgn0061188 lncRNA:Yu Yu http://flybase.org/reports/FBgn0061188 non_protein_coding_gene - - - "Yu, CR42645, yu" - CR42645 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0083952 CG34116 - http://flybase.org/reports/FBgn0083952 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR003656 molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG14103, CG34116" "IPR003656:Zinc finger, BED-type" CG34116 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036563 CG13075 - http://flybase.org/reports/FBgn0036563 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG13075 IPR002557:Chitin binding domain CG13075 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0062577 Mod(var)E1060 Mod(var)E1060 http://flybase.org/reports/FBgn0062577 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "E1060, Mod(var)E1060" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,enhancer of variegation,non-enhancer of variegation,non-suppressor of variegation" FBgn0001703 l(1)ESHS24 lethal (1) ESHS24 http://flybase.org/reports/FBgn0001703 - gene - - - l(1)ESHS24 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0037163 laza lazaro http://flybase.org/reports/FBgn0037163 protein_coding_gene phosphatidate phosphatase activity ; GO:0008195 | non-traceable author statement phosphatidate phosphatase activity ; GO:0008195 | inferred from sequence or structural similarity with HGNC:9228 phosphatidate phosphatase activity ; GO:0008195 | inferred from biological aspect of ancestor with PANTHER:PTN000017950 lipid phosphatase activity ; GO:0042577 | inferred from biological aspect of ancestor with PANTHER:PTN000807400 dephosphorylation ; GO:0016311 | non-traceable author statement thermotaxis ; GO:0043052 | inferred from direct assay phototransduction ; GO:0007602 | inferred from mutant phenotype inferred from genetic interaction with rdgB inferred from genetic interaction with rdgA phospholipid metabolic process ; GO:0006644 | inferred from biological aspect of ancestor with PANTHER:PTN001606015 response to light intensity ; GO:0009642 | inferred from mutant phenotype phospholipid dephosphorylation ; GO:0046839 | inferred from biological aspect of ancestor with PANTHER:PTN001606015 phototransduction ; GO:0007602 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from sequence or structural similarity with HGNC:9228 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001606015 "WUN-like, laza, Laza, CG11440, LPP-like, LPP" IPR000326:Phosphatidic acid phosphatase type 2/haloperoxidase CG11440 27-Aug-18 DroID_v2018_08 "Drer\plpp2b, Drer\plppr4a, Drer\plpp4, Drer\plppr1, Drer\plppr2b, Drer\plppr2a, Drer\LOC794598, Drer\ppap2d, Drer\plppr5a, Drer\plpp1a, Drer\plpp3, Drer\plppr3a, Drer\plppr3b, Drer\plpp2a, Drer\plppr5b, Drer\LOC571722, Drer\plpp5" "Scer\LPP1, Scer\DPP1" "Cele\T28D9.3, Cele\F53C3.13, Cele\T06D8.3, Cele\F13E6.5" "Xtro\plpp4, Xtro\plpp3, Xtro\plpp5, Xtro\plpp1, Xtro\LOC100135382, Xtro\plpp2" "Mmus\Plpp2, Mmus\Plppr2, Mmus\Plpp1, Mmus\Plppr1, Mmus\Plpp5, Mmus\Plpp3, Mmus\Plppr3, Mmus\Plppr5, Mmus\Plpp4, Mmus\Plppr4" "Hsap\PLPPR2, Hsap\PLPPR1, Hsap\PLPP2, Hsap\PLPPR5, Hsap\PLPP3, Hsap\PLPP4, Hsap\PLPP5, Hsap\PLPPR4, Hsap\PLPP1, Hsap\PLPPR3" "neurophysiology defective,viable,fertile,thermotaxis behavior defective" "eye,rhabdomere" FBgn0052279 Drsl2 Drosomycin-like 2 http://flybase.org/reports/FBgn0052279 protein_coding_gene molecular_function ; GO:0003674 | no biological data available defense response to fungus ; GO:0050832 | inferred from direct assay defense response to fungus ; GO:0050832 | inferred from sequence or structural similarity with Drs defense response to protozoan ; GO:0042832 | inferred from direct assay extracellular region ; GO:0005576 | inferred from sequence or structural similarity with Drs inferred from sequence model "Dro2, CT30310, Dro-D, CG10813, CG32279, Drs-lD, dro2, Drsl2, dmy2, dro-2" "IPR003614:Knottin, scorpion toxin-like" CG32279 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC08160 K 0.124052137 -0.889620755 0.224185389 -0.515382324 0.292733133 1.710552507 FBgn0015427 l(1)1Fg lethal (1) 1Fg http://flybase.org/reports/FBgn0015427 - gene - - - "D42, 4-134, l(1)1Fg" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0259193 Ir94d Ionotropic receptor 94d http://flybase.org/reports/FBgn0259193 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "CG17379, DmelIR94d, CG42297, Ir94d, IR94d" - CG42297 27-Aug-18 DroID_v2018_08 - - Cele\glr-7 - - - FBgn0038857 Bdbt Bride of doubletime http://flybase.org/reports/FBgn0038857 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with dco peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from biological aspect of ancestor with PANTHER:PTN000054102 FK506 binding ; GO:0005528 | inferred from biological aspect of ancestor with PANTHER:PTN000054102 regulation of post-translational protein modification ; GO:1901873 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | inferred from mutant phenotype chaperone-mediated protein folding ; GO:0061077 | inferred from biological aspect of ancestor with PANTHER:PTN000054102 regulation of protein catabolic process ; GO:0042176 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from direct assay "CG17282, Bdbt, bdbt" "IPR011990:Tetratricopeptide-like helical domain, IPR023566:Peptidyl-prolyl cis-trans isomerase, FKBP-type" CG17282 27-Aug-18 DroID_v2018_08 "Drer\fkbp10b, Drer\fkbp7, Drer\fkbp9, Drer\fkbp10a, Drer\fkbp2, Drer\fkbp14" - "Cele\fkb-5, Cele\fkb-4, Cele\fkb-3, Cele\fkb-1" - "Mmus\Fkbp14, Mmus\Fkbp9, Mmus\Fkbp2, Mmus\Fkbp7, Mmus\Fkbp10" "Hsap\FKBP9, Hsap\FKBP7, Hsap\FKBP2, Hsap\FKBP14, Hsap\FKBP10" "viable,visible,locomotor rhythm defective" "trichogen cell,supernumerary,tormogen cell,mesothoracic tergum" DRSC15218 E 0.306965522 -0.261764955 1.643426628 0.387140507 0.427029056 0.388126594 FBgn0069960 CG41053 - http://flybase.org/reports/FBgn0069960 protein_coding_gene - - - CG41053 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0283508 nw narrow http://flybase.org/reports/FBgn0283508 protein_coding_gene - regulation of imaginal disc-derived wing size ; GO:0044719 | inferred from mutant phenotype - "nw, CG43164, lance, Bla, CG33006, CG18431, CG4844a, CG4844, anon2D7, anon-EST:fe2D7, CG4844b" "IPR001304:C-type lectin-like, IPR016186:C-type lectin-like/link domain, IPR016187:C-type lectin fold" CG43164 27-Aug-18 DroID_v2018_08 - - "Cele\clec-50, Cele\clec-86" - - Hsap\REG1A DRSC06896 K -0.95973403 -0.697151696 -0.336705308 1.314712154 2.231660242 0.931839492 FBgn0005286 mei-S51 meiotic from via Salaria 51 http://flybase.org/reports/FBgn0005286 - gene molecular_function ; GO:0003674 | no biological data available female meiotic division ; GO:0007143 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mei-S51 - - 27-Aug-18 DroID_v2018_08 - - - - - - "meiotic cell cycle defective,female" FBgn0082997 snoRNA:Psi28S-1232 snoRNA:Psi28S-1232 http://flybase.org/reports/FBgn0082997 snoRNA_gene - - - "snoRNA:Psi28S-1232, Psi28S-1232, psi28S-1232, Psi 28S-1232, CR34592, psi-28S-1232" - CR34592 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263863 mRpL45 mitochondrial ribosomal protein L45 http://flybase.org/reports/FBgn0263863 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:Q9BRJ2 structural constituent of ribosome ; GO:0003735 | traceable author statement mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with UniProtKB:Q9BRJ2 mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement "CG6949, mRpL45, MRP-L45, l(3)dsl-8, l(3)dsl8, l(3)A8, XI-2, l(3)SG61" "IPR032710:NTF2-like domain, IPR007379:Tim44-like domain" CG6949 27-Aug-18 DroID_v2018_08 Drer\mrpl45 Scer\KRE29 Cele\mrpl-45 Xtro\mrpl45 Mmus\Mrpl45 Hsap\MRPL45 DRSC16146 E -0.2764334 0.171994131 -1.573378247 -0.246093997 -0.268290492 0.071577735 FBgn0259622 B0066 - http://flybase.org/reports/FBgn0259622 gene - - - B0066 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible wing vein FBgn0264816 koko kokopelli http://flybase.org/reports/FBgn0264816 protein_coding_gene cyclin-dependent protein serine/threonine kinase regulator activity ; GO:0016538 | inferred from biological aspect of ancestor with PANTHER:PTN000002458 positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from biological aspect of ancestor with PANTHER:PTN000002458 positive regulation of cyclin-dependent protein serine/threonine kinase activity ; GO:0045737 | inferred from biological aspect of ancestor with PANTHER:PTN000002458 positive regulation of phosphorylation of RNA polymerase II C-terminal domain ; GO:1901409 | inferred from biological aspect of ancestor with PANTHER:PTN000002458 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000002458 cyclin-dependent protein kinase holoenzyme complex ; GO:0000307 | inferred from biological aspect of ancestor with PANTHER:PTN000002458 "koko, CG7683, CG31232, CG44010" "IPR028759:Cyclin-related protein FAM58, IPR013763:Cyclin-like, IPR006671:Cyclin, N-terminal" CG44010 27-Aug-18 DroID_v2018_08 Drer\fam58a "Scer\SSN8, Scer\BUR2" - Xtro\fam58a Mmus\Fam58b Hsap\FAM58A "viable,fertile" FBgn0030970 CG7326 - http://flybase.org/reports/FBgn0030970 protein_coding_gene - - - CG7326 IPR019193:Ubiquitin-conjugating enzyme E2-binding protein CG7326 27-Aug-18 DroID_v2018_08 Drer\ube3d Scer\YJR141W - Xtro\ube3d Mmus\Ube2cbp Hsap\UBE3D "lethal,recessive,viable" FBgn0003152 Pigmentless Pigmentless http://flybase.org/reports/FBgn0003152 - gene - - - "Pigmentless, Ps" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,body color defective,dominant,female limited" adult abdomen & cuticle | female FBgn0262780 Su(E1)-N - http://flybase.org/reports/FBgn0262780 gene - - - Su(E1)-N - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0013260 E(var)48 E(var)48 http://flybase.org/reports/FBgn0013260 - gene - - - E(var)48 - - 27-Aug-18 DroID_v2018_08 - - - - - - "enhancer of variegation,dominant" FBgn0039226 Ude Uracil-DNA degrading factor http://flybase.org/reports/FBgn0039226 protein_coding_gene DNA binding ; GO:0003677 | inferred from direct assay uracil DNA N-glycosylase activity ; GO:0004844 | NOT inferred from direct assay RNA binding ; GO:0003723 | inferred from direct assay double-stranded RNA-specific ribonuclease activity ; GO:0032296 | NOT inferred from direct assay DNA catabolic process ; GO:0006308 | inferred from direct assay pupation ; GO:0035074 | inferred from expression pattern - "UDE, Ude, CG18410" - CG18410 27-Aug-18 DroID_v2018_08 - - Cele\F14F7.5 - - - "viable,fertile" FBgn0004007 we wee http://flybase.org/reports/FBgn0004007 - gene - - - we - - 27-Aug-18 DroID_v2018_08 - - - - - - "fertile,poor,small body" "eye,macrochaeta,wing" FBgn0032865 CG15477 - http://flybase.org/reports/FBgn0032865 protein_coding_gene - - - CG15477 - - 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0058271 CG40271 - http://flybase.org/reports/FBgn0058271 protein_coding_gene - - - CG40271 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0044338 297\gag 297 element gag http://flybase.org/reports/FBgn0044338 transposable_element_gene - - - "297\gag, gag" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0029697 CG15570 - http://flybase.org/reports/FBgn0029697 protein_coding_gene - - chorion ; GO:0042600 | inferred from direct assay CG15570 - CG15570 27-Aug-18 DroID_v2018_08 - - Cele\ssq-4 - - - viable FBgn0039999 CG17787 - http://flybase.org/reports/FBgn0039999 protein_coding_gene - - - "CG40398, CG17787" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0050391 CG30391 - http://flybase.org/reports/FBgn0050391 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG15662, CG30391" - CG30391 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0015434 l(1)4Da lethal (1) 4Da http://flybase.org/reports/FBgn0015434 - gene - - - l(1)4Da - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0066130 E(sda)C E(sda)C http://flybase.org/reports/FBgn0066130 gene - - - "E(sda)C, Line C" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039969 Fis1 "Fission, mitochondrial 1" http://flybase.org/reports/FBgn0039969 protein_coding_gene - positive regulation of mitochondrial fission ; GO:0090141 | inferred from mutant phenotype mitochondrion organization ; GO:0007005 | inferred from genetic interaction with Pink1 peroxisomal membrane ; GO:0005778 | inferred from sequence or structural similarity with HGNC:21689 "bs15a08.y1, BcDNA:RE29957, NEST:bs15a08, dFis1, Fis1, CG17510, fis1" "IPR011990:Tetratricopeptide-like helical domain, IPR033745:Mitochondria fission protein Fis1, cytosolic domain, IPR028061:Fis1, C-terminal tetratricopeptide repeat, IPR028058:Fis1, N-terminal tetratricopeptide repeat, IPR016543:Mitochondria fission 1 protein" CG17510 27-Aug-18 DroID_v2018_08 Drer\fis1 Scer\FIS1 "Cele\fis-1, Cele\fis-2" Xtro\fis1 Mmus\Fis1 Hsap\FIS1 FBgn0010883 l(3)06240 lethal (3) 06240 http://flybase.org/reports/FBgn0010883 - gene - - - l(3)06240 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0039034 Or94b Odorant receptor 94b http://flybase.org/reports/FBgn0039034 protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 "94b, DOR109, 94D.2, anon-JP2002534971-A.32, anon-JP2002534971-A.31, CG6679, Or94b" "IPR004117:Olfactory receptor, insect" CG6679 27-Aug-18 DroID_v2018_08 - - - - - - smell perception defective FBgn0022160 Gpo1 Glycerophosphate oxidase-1 http://flybase.org/reports/FBgn0022160 "FBgn0034048, FBgn0042124, FBgn0062235, FBgn0001129" protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 glycerol-3-phosphate dehydrogenase activity ; GO:0004368 | inferred from mutant phenotype glycerol-3-phosphate dehydrogenase activity ; GO:0004368 | inferred from sequence or structural similarity with UniProtKB:P43304 glycerol-3-phosphate metabolic process ; GO:0006072 | inferred from electronic annotation with InterPro:IPR000447 glycerol metabolic process ; GO:0006071 | inferred from sequence or structural similarity with UniProtKB:P43304 flight behavior ; GO:0007629 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype glycerophosphate shuttle ; GO:0006127 | inferred from mutant phenotype "glycerol-3-phosphate dehydrogenase complex ; GO:0009331 | inferred from electronic annotation with InterPro:IPR000447 mitochondrial inner membrane ; GO:0005743 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:P43304 lipid particle ; GO:0005811 | inferred from direct assay mitochondrion ; GO:0005739 | inferred by curator from GO:0004368,GO:0006127 mitochondrion ; GO:0005739 | inferred from direct assay" "l(2)k05713, CG8256, CG18786, anon-WO0118547.114, Gpo-1, alpha-GPO, alphaGPO, Gpo, GPO, GPO-1, CG 8256, 1(2) K05713" "IPR018247:EF-Hand 1, calcium-binding site, IPR000447:FAD-dependent glycerol-3-phosphate dehydrogenase, IPR002048:EF-hand domain, IPR006076:FAD dependent oxidoreductase, IPR011992:EF-hand domain pair, IPR031656:Alpha-glycerophosphate oxidase, C-terminal, IPR023753:FAD/NAD(P)-binding domain" CG8256 27-Aug-18 DroID_v2018_08 Drer\gpd2 Scer\GUT2 "Cele\T25G3.4, Cele\Y50E8A.6" Xtro\gpd2 Mmus\Gpd2 Hsap\GPD2 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage,recessive,viable,flightless" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0031939 CG13796 - http://flybase.org/reports/FBgn0031939 protein_coding_gene neurotransmitter:sodium symporter activity ; GO:0005328 | inferred from electronic annotation with InterPro:IPR000175 transporter activity ; GO:0005215 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 neurotransmitter transporter activity ; GO:0005326 | inferred from sequence or structural similarity with DAT neurotransmitter:sodium symporter activity ; GO:0005328 | inferred from sequence model neurotransmitter transport ; GO:0006836 | inferred from sequence or structural similarity with DAT neurotransmitter transport ; GO:0006836 | inferred from sequence model transport ; GO:0006810 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 integral component of membrane ; GO:0016021 | inferred from sequence model "CT42497, CG18590, CG13796, CG13796-PA" IPR000175:Sodium:neurotransmitter symporter CG13796 27-Aug-18 DroID_v2018_08 "Drer\slc6a4b, Drer\slc6a5, Drer\slc6a2, Drer\slc6a6a, Drer\slc6a9, Drer\slc6a1b, Drer\slc6a13, Drer\slc6a16a, Drer\slc6a1a, Drer\slc6a19a.2, Drer\slc6a18, Drer\slc6a1l, Drer\slc6a19a.1, Drer\si:ch211-117c9.5, Drer\slc6a8, Drer\slc6a17, Drer\slc6a15, Drer\slc6a4a, Drer\zgc:158225, Drer\slc6a14, Drer\slc6a19b" - Cele\snf-6 "Xtro\slc6a8, Xtro\slc6a14.2, Xtro\slc6a12, Xtro\slc6a6, Xtro\slc6a4, Xtro\slc6a15, Xtro\LOC100127682, Xtro\slc6a16, Xtro\slc6a3, Xtro\slc6a9, Xtro\slc6a5, Xtro\slc6a17, Xtro\slc6a7, Xtro\slc6a2, Xtro\slc6a19, Xtro\slc6a1" "Mmus\Slc6a3, Mmus\Slc6a21, Mmus\Slc6a1, Mmus\Slc6a15, Mmus\Slc6a12, Mmus\Slc6a8, Mmus\Slc6a20b, Mmus\Slc6a16, Mmus\Slc6a13, Mmus\Slc6a2, Mmus\Slc6a7, Mmus\Slc6a20a, Mmus\Slc6a9, Mmus\Slc6a18, Mmus\Slc6a11, Mmus\Slc6a4, Mmus\Slc6a19, Mmus\Slc6a5, Mmus\Slc6a6, Mmus\Slc6a17, Mmus\Slc6a14" "Hsap\SLC6A17, Hsap\SLC6A1, Hsap\SLC6A2, Hsap\SLC6A13, Hsap\SLC6A14, Hsap\SLC6A18, Hsap\SLC6A7, Hsap\SLC6A8, Hsap\SLC6A15, Hsap\SLC6A5, Hsap\SLC6A12, Hsap\SLC6A9, Hsap\SLC6A4, Hsap\SLC6A3, Hsap\SLC6A19, Hsap\SLC6A6, Hsap\SLC6A16, Hsap\SLC6A11, Hsap\SLC6A20" "viable,planar polarity defective" FBgn0022327 l(1)A27.2 lethal (1) A27.2 http://flybase.org/reports/FBgn0022327 - gene - - - "A27.2, l(1)A27.2" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0020339 anon-5Cc anon-5Cc http://flybase.org/reports/FBgn0020339 - gene - - - anon-5Cc - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264713 asRNA:CR43981 - http://flybase.org/reports/FBgn0264713 non_protein_coding_gene - - - CR43981 - CR43981 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0082190 l(3)S006603 lethal (3) S006603 http://flybase.org/reports/FBgn0082190 gene - - - l(3)S006603 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0037664 CG8420 - http://flybase.org/reports/FBgn0037664 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from sequence model "anon-WO0140519.182, CG8420" - CG8420 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0035932 CG13308 - http://flybase.org/reports/FBgn0035932 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 sensory perception of pain ; GO:0019233 | inferred from mutant phenotype extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG13308 IPR002557:Chitin binding domain CG13308 27-Aug-18 DroID_v2018_08 - - Cele\ZC84.1 - - - viable FBgn0052761 tRNA:Glu-CTC-6-1Psi transfer RNA:Glutamic acid-CTC 6-1 pseudogene http://flybase.org/reports/FBgn0052761 pseudogene_attribute - - - "AE002566.trna3-GluCTC, tRNA:EPsi:CTC:AE002566, CR32761, chrX.trna3-GluCTC, tRNA:Glu-CTC-6-1Psi, tRNA:CR32761:Psi, tRNA-Glu-CTC-6-1" - CR32761 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0010764 l(3)01949 lethal (3) 01949 http://flybase.org/reports/FBgn0010764 - gene - - - l(3)01949 - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0034179 CG6805 - http://flybase.org/reports/FBgn0034179 protein_coding_gene inositol trisphosphate phosphatase activity ; GO:0046030 | non-traceable author statement phosphatidylinositol dephosphorylation ; GO:0046856 | inferred from electronic annotation with InterPro:IPR000300 dephosphorylation ; GO:0016311 | non-traceable author statement - "IPP, CK01299, BEST:CK01299, CG6805" "IPR000300:Inositol polyphosphate-related phosphatase, IPR005135:Endonuclease/exonuclease/phosphatase" CG6805 27-Aug-18 DroID_v2018_08 "Drer\inpp5jb, Drer\inpp5j, Drer\inppl1b, Drer\inpp5b, Drer\inpp5kb, Drer\inpp5e, Drer\inppl1a, Drer\ocrl, Drer\inpp5d, Drer\sh2d1aa, Drer\inpp5ka" "Scer\INP51, Scer\INP54, Scer\INP53, Scer\INP52" Cele\cil-1 "Xtro\inpp5b, Xtro\inpp5d, Xtro\inpp5k, Xtro\sec16a, Xtro\inpp5j" "Mmus\Sh2d1b2, Mmus\Sh2d1a, Mmus\Inpp5j, Mmus\Inpp5d, Mmus\Inpp5k, Mmus\Inpp5e, Mmus\Ocrl, Mmus\Sh2d1b1, Mmus\Inppl1, Mmus\Inpp5b" "Hsap\SH2D1B, Hsap\INPP5K, Hsap\INPP5J, Hsap\INPP5D, Hsap\INPP5B, Hsap\OCRL, Hsap\INPP5E, Hsap\INPPL1" "viable,fertile" FBgn0033135 Tsp42En Tetraspanin 42En http://flybase.org/reports/FBgn0033135 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence model integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "CG12839, Dm.Tsp42En, BcDNA:RH02160, Tsp42En" "IPR018499:Tetraspanin/Peripherin, IPR000301:Tetraspanin, IPR008952:Tetraspanin, EC2 domain" CG12839 27-Aug-18 DroID_v2018_08 "Drer\cd63, Drer\tspan33b, Drer\tspan33a, Drer\zgc:113223" - "Cele\tsp-16, Cele\tsp-7, Cele\tsp-5" - "Mmus\Cd63, Mmus\Tspan32, Mmus\Tspan33" "Hsap\TSPAN32, Hsap\TSPAN15, Hsap\TSPAN33, Hsap\CD63" viable FBgn0050022 CG30022 - http://flybase.org/reports/FBgn0050022 protein_coding_gene iron ion binding ; GO:0005506 | inferred from sequence or structural similarity with HGNC:23287 glutathione metabolic process ; GO:0006749 | inferred from sequence or structural similarity with HGNC:23287 nucleoplasm ; GO:0005654 | inferred from sequence or structural similarity with HGNC:23287 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with HGNC:23287 "CG9026, BcDNA:RE56416, CG30022" IPR001279:Metallo-beta-lactamase CG30022 27-Aug-18 DroID_v2018_08 Drer\ethe1 "Scer\GLO2, Scer\GLO4" Cele\ethe-1 Xtro\ethe1 Mmus\Ethe1 Hsap\ETHE1 viable FBgn0028670 Vha100-2 Vacuolar H[+] ATPase 100kD subunit 2 http://flybase.org/reports/FBgn0028670 protein_coding_gene "proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | contributes_to inferred by curator from GO:0033181 ATPase binding ; GO:0051117 | inferred from biological aspect of ancestor with PANTHER:PTN000179505 proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from biological aspect of ancestor with PANTHER:PTN000179505 proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from sequence or structural similarity with SGD:S000005796" ATP hydrolysis coupled proton transport ; GO:0015991 | inferred by curator from GO:0033181 ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from sequence or structural similarity with SGD:S000005796 ATP synthesis coupled proton transport ; GO:0015986 | inferred from biological aspect of ancestor with PANTHER:PTN000179505 vacuolar acidification ; GO:0007035 | inferred from biological aspect of ancestor with PANTHER:PTN000179505 vacuolar proton-transporting V-type ATPase complex assembly ; GO:0070072 | inferred from biological aspect of ancestor with PANTHER:PTN000179505 "plasma membrane ; GO:0005886 | inferred from direct assay vacuolar proton-transporting V-type ATPase complex ; GO:0016471 | inferred from biological aspect of ancestor with PANTHER:PTN000179505 vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220 | inferred from sequence or structural similarity with SGD:S000005796 plasma membrane proton-transporting V-type ATPase complex ; GO:0033181 | inferred from mutant phenotype" "CG7679, vha100-2, CG18617, BcDNA:LD21735, anon-WO0118547.296, Vha100-2" "IPR002490:V-type ATPase, V0 complex, 116kDa subunit family, IPR026028:ATPase, V0 complex, subunit 116kDa, eukaryotic" CG18617 27-Aug-18 DroID_v2018_08 "Drer\atp6v0a2a, Drer\atp6v0a1b, Drer\tcirg1b, Drer\atp6v0a1a, Drer\atp6v0a2b, Drer\si:ch73-173p19.2, Drer\tcirg1a" "Scer\STV1, Scer\VPH1" "Cele\vha-6, Cele\vha-7, Cele\vha-5, Cele\unc-32" "Xtro\atp6v0a1, Xtro\atp6v0a2, Xtro\atp6v0a4, Xtro\tcirg1" "Mmus\Atp6v0a4, Mmus\Atp6v0a1, Mmus\Tcirg1, Mmus\Atp6v0a2" "Hsap\TCIRG1, Hsap\ATP6V0A4, Hsap\ATP6V0A2, Hsap\ATP6V0A1" "viable,lethal,recessive,fertile,visible" "chaeta,supernumerary" FBgn0259387 C255 - http://flybase.org/reports/FBgn0259387 gene - - - C255 - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,lethal" "wing hair,chaeta" FBgn0005303 Mot-K Mottled K http://flybase.org/reports/FBgn0005303 - gene - - - "Mo[K], Mot-K" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,visible,dominant" eye FBgn0050050 CG30050 - http://flybase.org/reports/FBgn0050050 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available CG30050 IPR010512:Protein of unknown function DUF1091 CG30050 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0262896 CG43251 - http://flybase.org/reports/FBgn0262896 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43251, lincRNA.639" - CG43251 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0052324 tRNA:Glu-CTC-3-7 transfer RNA:Glutamic acid-CTC 3-7 http://flybase.org/reports/FBgn0052324 tRNA_gene GAG codon-amino acid adaptor activity ; GO:0033460 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033460 cytosol ; GO:0005829 | inferred by curator from GO:0033460 "AE002584.trna9-GluCTC, tRNA:E:CTC:AE002584-g, CR32324, chr3L.trna9-GluCTC, tRNA:Glu-CTC-3-7, tRNA:CR32324, tRNA-Glu-CTC-3-7, GAG" - CR32324 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0067088 J18 J18 http://flybase.org/reports/FBgn0067088 gene - - - J18 - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,partially lethal - majority die,viable" eye FBgn0259435 EP-767.1 - http://flybase.org/reports/FBgn0259435 gene - - - EP-767.1 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible wing vein FBgn0267541 lncRNA:CR45881 - http://flybase.org/reports/FBgn0267541 non_protein_coding_gene - - - CR45881 - CR45881 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264393 CG43841 - http://flybase.org/reports/FBgn0264393 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43841, CG32551" - CG43841 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0010933 l(3)09143 lethal (3) 09143 http://flybase.org/reports/FBgn0010933 - gene - - - "l(3)9143, l(3)09143" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0067905 IM14 Immune induced molecule 14 http://flybase.org/reports/FBgn0067905 protein_coding_gene molecular_function ; GO:0003674 | no biological data available defense response ; GO:0006952 | inferred from direct assay response to bacterium ; GO:0009617 | inferred from expression pattern extracellular region ; GO:0005576 | inferred from direct assay "CG33990, DIM 14, IM14, im14" - CG33990 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264539 lncRNA:CR43918 - http://flybase.org/reports/FBgn0264539 non_protein_coding_gene - - - CR43918 - CR43918 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005298 mei-G17 meiotic G17 http://flybase.org/reports/FBgn0005298 - gene - - - mei-G17 - - 27-Aug-18 DroID_v2018_08 - - - - - - "meiotic cell cycle defective,male,recessive" meiosis I FBgn0035287 CG13937 - http://flybase.org/reports/FBgn0035287 protein_coding_gene "sulfotransferase activity ; GO:0008146 | inferred from electronic annotation with InterPro:IPR005331, InterPro:IPR018011" carbohydrate biosynthetic process ; GO:0016051 | inferred from electronic annotation with InterPro:IPR018011 "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005331, InterPro:IPR018011" "CG13937, d4ST2" "IPR005331:Sulfotransferase, IPR018011:Carbohydrate sulfotransferase 8-10, IPR015943:WD40/YVTN repeat-like-containing domain" CG13937 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-26i13.3, Drer\si:dkey-26i13.4, Drer\si:dkey-26i13.7, Drer\LOC100536144, Drer\chst11, Drer\si:dkey-26i13.6, Drer\chst12b, Drer\chst8, Drer\chst12a, Drer\si:ch211-236h17.3, Drer\si:dkey-26i13.5, Drer\si:ch211-269c21.2, Drer\chst10" - - Xtro\chst8 "Mmus\Chst13, Mmus\Chst8, Mmus\Chst12, Mmus\Chst11, Mmus\Chst9, Mmus\Chst10" "Hsap\CHST12, Hsap\CHST8, Hsap\CHST11, Hsap\CHST13, Hsap\CHST10, Hsap\CHST9" viable FBgn0260078 2L3651 - http://flybase.org/reports/FBgn0260078 gene - - - 2L3651 - - 27-Aug-18 DroID_v2018_08 - - - - - - "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0053458 CG33458 - http://flybase.org/reports/FBgn0053458 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - CG33458 "IPR018114:Serine proteases, trypsin family, histidine active site, IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan, IPR001314:Peptidase S1A, chymotrypsin family" CG33458 27-Aug-18 DroID_v2018_08 "Drer\prss56, Drer\masp2" - Cele\try-3 - "Mmus\Prss56, Mmus\Egfbp2" Hsap\PRSS56 viable FBgn0014197 l(1)14Cd lethal (1) 14Cd http://flybase.org/reports/FBgn0014197 - gene - - - "l(1)14Ce, l(1)14Cd" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" "ovariole,germline clone" FBgn0065197 l(2)SH2320 lethal (2) SH2320 http://flybase.org/reports/FBgn0065197 gene - - - "l(2)SH2320, l(2)SH2 2320" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0266505 s-334 - http://flybase.org/reports/FBgn0266505 gene - - - s-334 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0082632 S(CycE[JP])2.6 S(CycE[JP])2.6 http://flybase.org/reports/FBgn0082632 gene - - - S(CycE[JP])2.6 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0264821 asRNA:CR44029 - http://flybase.org/reports/FBgn0264821 non_protein_coding_gene - - - CR44029 - CR44029 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0082617 S(CycE[JP])68S10 S(CycE[JP])68S10 http://flybase.org/reports/FBgn0082617 gene - - - "68S10, S(CycE[JP])68S10" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0083305 E(smoDN)1551 Enhancer of smoDN 1551 http://flybase.org/reports/FBgn0083305 gene - - - E(smoDN)1551 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0023134 WppI White prepupal locus I http://flybase.org/reports/FBgn0023134 - gene - - - "37, 22A, 10, WppI" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262970 CR43281 - http://flybase.org/reports/FBgn0262970 pseudogene_attribute - - - CR43281 - CR43281 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0028176 l(3)S026115b lethal (3) S026115b http://flybase.org/reports/FBgn0028176 gene - - - "0261/15, l(3)S026115, l(3)S026115b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0063398 Stalker2\ORF1 Stalker2 element ORF1 http://flybase.org/reports/FBgn0063398 transposable_element_gene - - - "rom\ORF1, Stalker2\ORF1" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040082 p82 p82 http://flybase.org/reports/FBgn0040082 gene - - - p82 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0052666 Drak Death-associated protein kinase related http://flybase.org/reports/FBgn0052666 protein_coding_gene protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000678761 ATP binding ; GO:0005524 | inferred from biological aspect of ancestor with PANTHER:PTN000678761 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement regulation of cell shape ; GO:0008360 | inferred from mutant phenotype imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype cell adhesion ; GO:0007155 | inferred from mutant phenotype morphogenesis of an epithelium ; GO:0002009 | inferred from genetic interaction with Rok protein phosphorylation ; GO:0006468 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000678761 "CG1760, EP(X)1452, CG11713, EP1452, Drak, CG32666, drak" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain" CG32666 27-Aug-18 DroID_v2018_08 "Drer\zgc:153952, Drer\mylk4a, Drer\camkva, Drer\mylk4b, Drer\ttnb, Drer\si:ch73-60h1.1, Drer\camkvb, Drer\camk1ga, Drer\pskh1, Drer\trioa, Drer\dapk2b, Drer\camkvl, Drer\triob, Drer\dapk3, Drer\stk17b, Drer\pnck, Drer\camk1db, Drer\capsla, Drer\uhmk1, Drer\camk1da, Drer\capslb, Drer\camk1b, Drer\si:dkey-240h12.4, Drer\camk1gb, Drer\spegb, Drer\stk33, Drer\camk1a, Drer\camk4, Drer\si:ch211-27e6.1, Drer\dapk1, Drer\dapk2a, Drer\mylk3, Drer\stk17a" "Scer\PKH2, Scer\TDA1, Scer\RCK1, Scer\RCK2, Scer\IKS1, Scer\PKH1, Scer\CMK2, Scer\MEK1, Scer\RAD53, Scer\CMK1" Cele\F32D8.1 "Xtro\dapk2, Xtro\mylk3, Xtro\capsl, Xtro\kalrn, Xtro\dclk2, Xtro\pskh1, Xtro\mark2, Xtro\camk1d, Xtro\camk4, Xtro\camkv, Xtro\stk17a, Xtro\pnck, Xtro\stk33, Xtro\dapk3, Xtro\camk1, Xtro\camk1g, Xtro\trio, Xtro\caps, Xtro\pskh2, Xtro\mylk4, Xtro\dapk1" "Mmus\Dclk2, Mmus\Dclk1, Mmus\Pnck, Mmus\Capsl, Mmus\Mapk7, Mmus\Trio, Mmus\Mylk2, Mmus\Dapk1, Mmus\Dapk3, Mmus\Uhmk1, Mmus\Speg, Mmus\Stk17b, Mmus\Dapk2, Mmus\Mylk3, Mmus\Pskh1, Mmus\Camk1, Mmus\Camk1g, Mmus\Obscn, Mmus\Mylk4, Mmus\Caps2, Mmus\Camkv, Mmus\Camk1d, Mmus\Stk33, Mmus\Camk4" "Hsap\DAPK1, Hsap\MYLK3, Hsap\PSKH2, Hsap\TRIO, Hsap\UHMK1, Hsap\SPEG, Hsap\PNCK, Hsap\DAPK2, Hsap\DCLK1, Hsap\CAPS2, Hsap\MYLK4, Hsap\CAMK4, Hsap\NEK4, Hsap\STK17A, Hsap\MYLK2, Hsap\PSKH1, Hsap\DAPK3, Hsap\STK33, Hsap\CAMK1G, Hsap\CAPS, Hsap\STK17B, Hsap\CAMK1, Hsap\OBSCN, Hsap\CAMKV, Hsap\CAPSL, Hsap\CAMK1D" "viable,fertile,visible,lethal" "wing,metathoracic leg,chaeta,supernumerary" FBgn0260044 33R6 - http://flybase.org/reports/FBgn0260044 gene - - - 33R6 - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,somatic clone" "wing,somatic clone" FBgn0000707 fltM flight defective M http://flybase.org/reports/FBgn0000707 - gene - - - fltM - - 27-Aug-18 DroID_v2018_08 - - - - - - flight defective FBgn0023045 l(1)3Bg lethal (1) 3Bg http://flybase.org/reports/FBgn0023045 - gene - - - "B2/50.8, l(1)3Bg" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0014141 cher cheerio http://flybase.org/reports/FBgn0014141 "FBgn0016063, FBgn0023208" protein_coding_gene actin binding ; GO:0003779 | inferred from sequence or structural similarity actin binding ; GO:0003779 | inferred from sequence or structural similarity with HGNC:3754 "motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype germline ring canal formation ; GO:0030725 | inferred from mutant phenotype germarium-derived female germ-line cyst encapsulation ; GO:0030708 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from expression pattern cytoplasmic transport, nurse cell to oocyte ; GO:0007303 | inferred from mutant phenotype female germline ring canal formation, actin assembly ; GO:0008302 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype negative regulation of lamellocyte differentiation ; GO:0035204 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype positive regulation of cytoskeleton organization ; GO:0051495 | inferred from mutant phenotype learning or memory ; GO:0007611 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype long-term memory ; GO:0007616 | inferred from mutant phenotype female germline ring canal formation ; GO:0007301 | inferred from mutant phenotype protein localization ; GO:0008104 | inferred from mutant phenotype" actin filament ; GO:0005884 | colocalizes_with inferred from direct assay contractile ring ; GO:0070938 | colocalizes_with inferred from direct assay female germline ring canal ; GO:0035324 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay perinuclear region of cytoplasm ; GO:0048471 | colocalizes_with inferred from direct assay female germline ring canal inner rim ; GO:0035183 | inferred from direct assay nucleus ; GO:0005634 | colocalizes_with inferred from direct assay female germline ring canal outer rim ; GO:0035182 | inferred from direct assay apical cortex ; GO:0045179 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay actin cytoskeleton ; GO:0015629 | inferred from direct assay "cher, CG3937, FLN, sko, Fil, Cher, joy, FLN90" "IPR001298:Filamin/ABP280 repeat, IPR001589:Actinin-type actin-binding domain, conserved site, IPR001715:Calponin homology domain, IPR013783:Immunoglobulin-like fold, IPR014756:Immunoglobulin E-set, IPR017868:Filamin/ABP280 repeat-like" CG3937 27-Aug-18 DroID_v2018_08 "Drer\flnbl, Drer\flnca, Drer\flna, Drer\flnb, Drer\flncb, Drer\LOC100534866" - "Cele\fln-1, Cele\fln-2" "Xtro\flna, Xtro\flnc, Xtro\flnb" "Mmus\Flnc, Mmus\Flna, Mmus\Flnb" "Hsap\FLNA, Hsap\FLNC, Hsap\FLNB" " adult stage , adult stage && oogenesis stage " " follicle cell

, inner nurse cell ring canal rim

, ring canal

, fusome

, outer nurse cell ring canal rim

, ovariole | surrounding

, ovariole

, nurse cell

, interfollicle cell

" "female sterile,recessive,learning defective,memory defective,neuroanatomy defective,viable,fertile,chemical sensitive,visible,short lived,locomotor behavior defective,uncoordinated,heat sensitive,male fertile,long lived" "nurse cell ring canal,egg chamber,border follicle cell,interfollicle cell,germarium region 2b & interfollicle cell,follicle cell,intersegmental nerve,ommatidium,ovary,ovariole,germarium,nurse cell,plasma membrane & nurse cell,plasma membrane & oocyte,nurse cell & nucleus,centripetally migrating follicle cell,nurse cell & plasma membrane,oocyte,inner nurse cell ring canal rim,lamellocyte,ectopic" FBgn0266109 mei-114 meiotic 114 http://flybase.org/reports/FBgn0266109 gene - female meiotic division ; GO:0007143 | inferred from mutant phenotype - mei-114 - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,meiotic cell cycle defective,female" FBgn0014353 ms(3)ry5 ms(3)ry5 http://flybase.org/reports/FBgn0014353 FBgn0013666 gene - - - "ms(3)5, ms(3)ry5" - - 27-Aug-18 DroID_v2018_08 - - - - - - male sterile FBgn0027248 l(1)G0260 lethal (1) G0260 http://flybase.org/reports/FBgn0027248 - gene - - - l(1)G0260 - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,lethal,partially lethal - majority die,recessive" FBgn0013732 sced scrambled http://flybase.org/reports/FBgn0013732 FBgn0033082 protein_coding_gene - actin filament reorganization involved in cell cycle ; GO:0030037 | inferred from mutant phenotype pseudocleavage involved in syncytial blastoderm formation ; GO:0030589 | inferred from mutant phenotype centrosome ; GO:0005813 | inferred from direct assay "CT9143, CG3273, sced, Sced" - CG3273 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,maternal effect,recessive,fertile,female sterile,viable" "embryonic/larval hemocyte | third instar larval stage,cycle 9 embryo,maternal effect,cycle 10 embryo,cycle 11 embryo,cycle 12 embryo,cycle 13 embryo,cycle 14 embryo" FBgn0041177 Ubx::Akap\Ubx Ubx::Akap\Ubx http://flybase.org/reports/FBgn0041177 engineered_fusion_gene - - - Ubx::Akap\Ubx - - 27-Aug-18 DroID_v2018_08 - - - - - - "embryonic metathoracic segment,embryonic abdominal segment 1,ectopic,leg,antenna,haltere,wing,embryonic epidermis,abdominal 1 ventral denticle belt,Kolbchen" FBgn0034194 CG15611 - http://flybase.org/reports/FBgn0034194 protein_coding_gene Rho guanyl-nucleotide exchange factor activity ; GO:0005089 | inferred from sequence or structural similarity with trio response to endoplasmic reticulum stress ; GO:0034976 | inferred from mutant phenotype positive regulation of Rho protein signal transduction ; GO:0035025 | inferred from sequence or structural similarity with trio cellular_component ; GO:0005575 | no biological data available CG15611 "IPR000219:Dbl homology (DH) domain, IPR011993:PH domain-like" CG15611 27-Aug-18 DroID_v2018_08 "Drer\quo, Drer\triob, Drer\arhgef25a, Drer\plekhg4, Drer\si:dkey-91i10.2, Drer\trioa, Drer\si:dkey-65j6.2, Drer\zgc:158766, Drer\LOC101883939, Drer\arhgef25b, Drer\arhgef40, Drer\kalrnb, Drer\kalrna" "Scer\CDC24, Scer\ROM1, Scer\ROM2" "Cele\tiam-1, Cele\unc-73, Cele\Y95B8A.12, Cele\cgef-1" "Xtro\kalrn, Xtro\arhgef40" "Mmus\Kalrn, Mmus\Arhgef25, Mmus\Arhgef40, Mmus\D630003M21Rik, Mmus\Trio, Mmus\Tiam1, Mmus\Plekhg4" "Hsap\PLEKHG4, Hsap\TRIO, Hsap\TIAM1, Hsap\PLEKHG4B, Hsap\ARHGEF25, Hsap\ARHGEF40, Hsap\KALRN" viable FBgn0267081 asRNA:CR45525 - http://flybase.org/reports/FBgn0267081 non_protein_coding_gene - - - CR45525 - CR45525 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065299 l(2)SH1992 lethal (2) SH1992 http://flybase.org/reports/FBgn0065299 gene - - - "l(2)SH1992, l(2)SH2 1992" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0265706 lncRNA:CR44513 - http://flybase.org/reports/FBgn0265706 non_protein_coding_gene - - - "lincRNA.399, CR44513" - CR44513 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0086673 CG13272 - http://flybase.org/reports/FBgn0086673 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG13272, CG33312" IPR015943:WD40/YVTN repeat-like-containing domain CG13272 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0019778 l(1)31 lethal (1) 31 http://flybase.org/reports/FBgn0019778 - gene - - - l(1)31 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0013238 E(var)2 E(var)2 http://flybase.org/reports/FBgn0013238 - gene - - - E(var)2 - - 27-Aug-18 DroID_v2018_08 - - - - - - "enhancer of variegation,dominant" FBgn0004205 l(3)84Ec lethal (3) 84Ec http://flybase.org/reports/FBgn0004205 - gene - - - l(3)84Ec - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0065786 l(2)SH0435 lethal (2) SH0435 http://flybase.org/reports/FBgn0065786 gene - - - "l(2)SH0435, l(2)SH2 0435" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0051833 CG31833 - http://flybase.org/reports/FBgn0051833 protein_coding_gene - - - CG31833 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085828 CR42195 - http://flybase.org/reports/FBgn0085828 rRNA_gene - - - CR42195 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0011534 l(3)00707 lethal (3) 00707 http://flybase.org/reports/FBgn0011534 - gene - - - l(3)00707 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0005072 fs(2)OW213 female sterile (2) OW213 http://flybase.org/reports/FBgn0005072 - gene - - - fs(2)OW213 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030215 CG15296 - http://flybase.org/reports/FBgn0030215 protein_coding_gene - - - "BcDNA:AT26906, CG15296" IPR026769:MICOS complex subunit Mic13 CG15296 27-Aug-18 DroID_v2018_08 - - - - - Hsap\C19orf70 "fertile,viable" FBgn0034275 CG5002 - http://flybase.org/reports/FBgn0034275 protein_coding_gene secondary active sulfate transmembrane transporter activity ; GO:0008271 | inferred from electronic annotation with InterPro:IPR001902 bicarbonate transmembrane transporter activity ; GO:0015106 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 anion:anion antiporter activity ; GO:0015301 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 sulfate transmembrane transporter activity ; GO:0015116 | inferred from biological aspect of ancestor with PANTHER:PTN000212031 oxalate transmembrane transporter activity ; GO:0019531 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 chloride channel activity ; GO:0005254 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 "sulfate transport ; GO:0008272 | inferred from electronic annotation with InterPro:IPR001902, InterPro:IPR011547 bicarbonate transport ; GO:0015701 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 chloride transmembrane transport ; GO:1902476 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 regulation of membrane potential ; GO:0042391 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 regulation of intracellular pH ; GO:0051453 | inferred from biological aspect of ancestor with PANTHER:PTN000212047" integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000212031 CG5002 "IPR002645:STAS domain, IPR011547:SLC26A/SulP transporter domain, IPR001902:SLC26A/SulP transporter" CG5002 27-Aug-18 DroID_v2018_08 "Drer\slc26a2, Drer\slc26a10, Drer\slc26a1, Drer\slc26a6, Drer\si:ch211-117c9.2, Drer\slc26a3.2, Drer\slc26a11, Drer\slc26a3.1, Drer\slc26a6l, Drer\slc26a5, Drer\slc26a4" "Scer\YPR003C, Scer\YGR125W, Scer\SUL1, Scer\SUL2" "Cele\sulp-4, Cele\sulp-6, Cele\sulp-5, Cele\sulp-8, Cele\sulp-1, Cele\sulp-2, Cele\sulp-3, Cele\sulp-7" "Xtro\slc26a4, Xtro\slc26a7, Xtro\slc26a10, Xtro\slc26a1, Xtro\slc26a9, Xtro\slc26a11, Xtro\slc26a5, Xtro\slc26a2, Xtro\slc26a6" "Mmus\Slc26a9, Mmus\Slc26a7, Mmus\Slc26a8, Mmus\Slc26a6, Mmus\Slc26a5, Mmus\Slc26a4, Mmus\Slc26a10, Mmus\Slc26a3, Mmus\Slc26a2, Mmus\Slc26a11, Mmus\Slc26a1" "Hsap\SLC26A11, Hsap\SLC26A4, Hsap\SLC26A9, Hsap\SLC26A6, Hsap\SLC26A5, Hsap\SLC26A8, Hsap\SLC26A3, Hsap\SLC26A1, Hsap\SLC26A7, Hsap\SLC26A2, Hsap\SLC26A10" viable FBgn0016660 H15 H15 http://flybase.org/reports/FBgn0016660 - protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR001699, InterPro:IPR002070, InterPro:IPR008967, InterPro:IPR018186" neurogenesis ; GO:0022008 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay cardioblast cell fate commitment ; GO:0042684 | inferred from mutant phenotype heart development ; GO:0007507 | inferred from mutant phenotype heart process ; GO:0003015 | inferred from direct assay leg disc pattern formation ; GO:0035223 | inferred from genetic interaction with mid regulation of cell fate specification ; GO:0042659 | inferred from genetic interaction with mid chorion-containing eggshell pattern formation ; GO:0030381 | inferred from mutant phenotype embryonic heart tube development ; GO:0035050 | inferred from mutant phenotype "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR001699, InterPro:IPR002070, InterPro:IPR018186" "Nmr-1, CG6604, nmr1, H15, Dm-H15, nmr, dm-H15, Nmr, nmr[H15], Tbx20" "IPR018186:Transcription factor, T-box, conserved site, IPR001699:Transcription factor, T-box, IPR002070:Transcription factor, Brachyury, IPR008967:p53-like transcription factor, DNA-binding" CG6604 27-Aug-18 DroID_v2018_08 "Drer\tbx5b, Drer\tbx15, Drer\tbx1, Drer\eomesa, Drer\tbx16, Drer\eomesb, Drer\tbx5a, Drer\tbx2b, Drer\tbx20, Drer\tbr1b, Drer\tbr1a, Drer\grap2b, Drer\mgaa, Drer\tbx3b, Drer\tbx2a, Drer\tbx22, Drer\tbx18, Drer\tbx21, Drer\tbx6" - "Cele\mls-1, Cele\tbx-2, Cele\tbx-7, Cele\tbx-43, Cele\mab-9" "Xtro\tbx20, Xtro\tbx4, Xtro\tbx3, Xtro\tbx18, Xtro\tbx5, Xtro\tbx22, Xtro\tbx2, Xtro\tbx1, Xtro\tbx15, Xtro\vegt, Xtro\mga" "Mmus\Tbx22, Mmus\Tbx20, Mmus\Tbx4, Mmus\Tbx18, Mmus\Tbx5, Mmus\Tbx3, Mmus\Mga, Mmus\Tbr1, Mmus\Tbx15, Mmus\Tbx1, Mmus\Tbx2, Mmus\Tbx21, Mmus\Tbx6, Mmus\Tbx10, Mmus\Eomes" "Hsap\TBX20, Hsap\TBX2, Hsap\TBX1, Hsap\TBR1, Hsap\TBX4, Hsap\TBX15, Hsap\MGA, Hsap\TBX18, Hsap\TBX3, Hsap\TBX22, Hsap\TBX10, Hsap\TBX5, Hsap\EOMES, Hsap\TBX21, Hsap\TBX6" "viable,lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "dorsal appendage,somatic clone,embryonic/larval neuroblast,ganglion mother cell" FBgn0036183 CG6083 - http://flybase.org/reports/FBgn0036183 protein_coding_gene "oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR018170, InterPro:IPR020471" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR018170, InterPro:IPR020471 mushroom body development ; GO:0016319 | inferred from mutant phenotype" - CG6083 "IPR018170:Aldo/keto reductase, conserved site, IPR020471:Aldo/keto reductase, IPR023210:NADP-dependent oxidoreductase domain" CG6083 27-Aug-18 DroID_v2018_08 "Drer\zgc:110782, Drer\si:dkey-180p18.9, Drer\akr1a1b, Drer\zgc:56622, Drer\zgc:110366, Drer\zgc:101765, Drer\akr1b1, Drer\akr1a1a" "Scer\ARA1, Scer\GCY1, Scer\GRE3, Scer\YPR1, Scer\YDL124W, Scer\YJR096W" "Cele\T08H10.1, Cele\ZK1290.5, Cele\F53F1.2, Cele\Y39G8B.1, Cele\C56G3.2, Cele\F53F1.3, Cele\ZC443.1, Cele\C35D10.6, Cele\K07C5.2, Cele\C01G5.5, Cele\C07D8.6, Cele\Y39G8B.2" "Xtro\akr1c1, Xtro\akr1c2, Xtro\LOC548351, Xtro\akr1a1, Xtro\akr1d1, Xtro\akr1c8p, Xtro\akr1b1" "Mmus\Akr1b10, Mmus\Akr1cl, Mmus\Akr1c6, Mmus\Akr1e1, Mmus\Akr1c12, Mmus\Akr1c20, Mmus\Akr1b7, Mmus\Akr1c19, Mmus\Akr1a1, Mmus\Akr1b3, Mmus\Akr1c14, Mmus\Akr1c21, Mmus\Akr1c18, Mmus\Akr1d1, Mmus\Akr1c13, Mmus\Akr1b8" "Hsap\AKR1B10, Hsap\AKR1B1, Hsap\AKR1C4, Hsap\AKR1B15, Hsap\AKR1E2, Hsap\AKR1C2, Hsap\AKR1C1, Hsap\AKR1D1, Hsap\AKR1C3, Hsap\AKR1A1" "neuroanatomy defective,viable" adult mushroom body DRSC24586 K 0.364844955 -0.05629393 0.593022292 0.681049727 -0.298706111 -1.597114604 FBgn0001808 l(1)Mc56 lethal (1) Mc56 http://flybase.org/reports/FBgn0001808 - gene - - - l(1)Mc56 - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,somatic clone,lethal - all die before end of larval stage,recessive,some die during larval stage" "wing,somatic clone" FBgn0020788 rABP70 ribosomal 'Alu-repeat' binding protein 70 http://flybase.org/reports/FBgn0020788 - gene - - - rABP70 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0016026 l(3)89Ce lethal (3) 89Ce http://flybase.org/reports/FBgn0016026 - gene - - - l(3)89Ce - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0265426 lncRNA:CR44338 - http://flybase.org/reports/FBgn0265426 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG44338, CR44338" - CR44338 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0016069 slinky slinky http://flybase.org/reports/FBgn0016069 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available slinky - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0050045 Cpr49Aa Cuticular protein 49Aa http://flybase.org/reports/FBgn0050045 protein_coding_gene structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "CG8496, Cpr49Aa, CG30045, DmelCpr49Aa" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG30045 27-Aug-18 DroID_v2018_08 Drer\LOC100003040 - "Cele\math-34, Cele\F44F1.4, Cele\sdz-30" - "Mmus\H2-K1, Mmus\2410137M14Rik" - FBgn0011151 l(1)Q227 lethal (1) Q227 http://flybase.org/reports/FBgn0011151 FBgn0010210 gene - - - l(1)Q227 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0038880 SIFaR SIFamide receptor http://flybase.org/reports/FBgn0038880 protein_coding_gene neuropeptide Y receptor activity ; GO:0004983 | inferred from electronic annotation with InterPro:IPR000611 G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity neuropeptide receptor activity ; GO:0008188 | inferred from sequence model neuropeptide receptor activity ; GO:0008188 | inferred from physical interaction with SIFa G-protein coupled peptide receptor activity ; GO:0008528 | inferred from sequence or structural similarity "mating behavior, sex discrimination ; GO:0048047 | inferred from mutant phenotype G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype" integral component of membrane ; GO:0016021 | inferred from sequence model integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred from direct assay "SIFR, CG10823, anon-WO0170980.44, anon-WO0170980.43, DrmSIFR, SIF-R, SIFa-R, SIFaR" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR000611:Neuropeptide Y receptor family, IPR017452:GPCR, rhodopsin-like, 7TM" CG10823 27-Aug-18 DroID_v2018_08 "Drer\prlh2r, Drer\ccr7, Drer\si:dkey-211g8.1, Drer\cxcr4b, Drer\sc:d217, Drer\igsf9ba, Drer\ackr3a, Drer\npffr1l1, Drer\xcr1b.1, Drer\si:dkey-117a8.1, Drer\cxcr2, Drer\LOC793148, Drer\ccdc141, Drer\ccr8.1, Drer\si:ch73-160i9.3, Drer\ccr12b.1, Drer\ccr9b, Drer\cntn1a, Drer\npffr1l2, Drer\ackr4a, Drer\igsf9bb, Drer\LOC101884253, Drer\cxcr4a, Drer\zgc:194312, Drer\LOC100535965, Drer\ccr12a, Drer\npffr1l3, Drer\LOC103908669, Drer\cntn1b, Drer\LOC561565, Drer\cabz01093075.1, Drer\neo1a, Drer\ccr12b.2, Drer\npffr2a, Drer\LOC100006764, Drer\LOC797181, Drer\si:ch211-207g17.3, Drer\cntn2, Drer\ccr6a, Drer\si:dkey-202l22.3, Drer\xcr1a.1, Drer\ccr9a, Drer\LOC100151078, Drer\si:ch73-160i9.1, Drer\si:ch211-240b21.5, Drer\si:dkey-42l23.7, Drer\npy7r, Drer\si:dkey-42l23.5, Drer\ackr3b, Drer\LOC793479, Drer\xcr1b.2, Drer\ackr4b, Drer\si:ch211-171h4.6, Drer\cmklr1" - "Cele\npr-22, Cele\npr-35, Cele\ckr-1, Cele\tkr-3, Cele\npr-11" "Xtro\LOC100491949, Xtro\npffr2" "Mmus\Ccr3, Mmus\Cx3cr1, Mmus\Ccr1l1, Mmus\Ackr3, Mmus\Ccr10, Mmus\Cntn2, Mmus\Ackr4, Mmus\Ackr2, Mmus\Cntn1, Mmus\Npffr1, Mmus\Ccr5, Mmus\Cxcr2, Mmus\Cxcr6, Mmus\Neo1, Mmus\Ccr4, Mmus\Dcc, Mmus\Cxcr5, Mmus\Ccr8, Mmus\Igsf9b, Mmus\Ccr9, Mmus\Ccr6, Mmus\Xcr1, Mmus\Cxcr4, Mmus\Npffr2, Mmus\Ccdc141, Mmus\Cxcr1, Mmus\Ccr1, Mmus\Ccr2, Mmus\Ccr7, Mmus\Cxcr3, Mmus\Ccrl2, Mmus\Cmklr1" "Hsap\CNTN2, Hsap\CXCR4, Hsap\CCDC141, Hsap\CCR7, Hsap\CCR10, Hsap\NPFFR1, Hsap\ACKR3, Hsap\CNTN1, Hsap\XCR1, Hsap\CCR9, Hsap\CCR3, Hsap\NPFFR2, Hsap\CXCR1, Hsap\CCR8, Hsap\CMKLR1, Hsap\CCR5, Hsap\CX3CR1, Hsap\ACKR4, Hsap\CCR1, Hsap\ACKR2, Hsap\CCR2, Hsap\CCR4, Hsap\IGSF9B, Hsap\CXCR2, Hsap\DCC, Hsap\CXCR3, Hsap\CXCR5, Hsap\CXCR6, Hsap\CCR6, Hsap\NEO1, Hsap\CCRL2" "long lived,viable" FBgn0264410 FCE-C - http://flybase.org/reports/FBgn0264410 gene - - - FCE-C - - 27-Aug-18 DroID_v2018_08 - - - - - - "egg chamber,somatic clone" FBgn0035911 CG6638 - http://flybase.org/reports/FBgn0035911 protein_coding_gene flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR013786 isovaleryl-CoA dehydrogenase activity ; GO:0008470 | inferred from sequence or structural similarity with UniProtKB:P26440 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006089, InterPro:IPR006091, InterPro:IPR009075, InterPro:IPR009100, InterPro:IPR013786 leucine catabolic process ; GO:0006552 | inferred from sequence or structural similarity with UniProtKB:P26440" mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:P26440 CG6638 "IPR006089:Acyl-CoA dehydrogenase, conserved site, IPR006091:Acyl-CoA oxidase/dehydrogenase, central domain, IPR009075:Acyl-CoA dehydrogenase/oxidase C-terminal, IPR009100:Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain, IPR013786:Acyl-CoA dehydrogenase/oxidase, N-terminal, IPR034183:Isovaleryl-CoA dehydrogenase" CG6638 27-Aug-18 DroID_v2018_08 "Drer\acad9, Drer\acadl, Drer\acadvl, Drer\acads, Drer\acad8, Drer\acadm, Drer\ivd" - "Cele\acdh-8, Cele\acdh-9, Cele\acdh-4, Cele\acdh-1, Cele\acdh-7, Cele\ivd-1" "Xtro\acadl, Xtro\acad8, Xtro\acadsb, Xtro\ivd, Xtro\acad9, Xtro\acads, Xtro\acadm" "Mmus\Acad8, Mmus\Acad9, Mmus\Acads, Mmus\Ivd, Mmus\Acadl, Mmus\Acadvl, Mmus\Acadsb, Mmus\Acadm" "Hsap\ACAD9, Hsap\ACADVL, Hsap\IVD, Hsap\ACADM, Hsap\ACADS, Hsap\ACADL, Hsap\ACADSB, Hsap\ACAD8" FBgn0004679 Esm Enhancer of split mimic http://flybase.org/reports/FBgn0004679 - gene - - - Esm - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0285955 cv-c C5 http://flybase.org/reports/FBgn0028839 gene - - - C5 - - 27-Aug-18 DroID_v2018_08 - - - - - - "locomotor behavior defective,dominant,viable" FBgn0053451 5SrRNA:CR33451 5SrRNA:CR33451 http://flybase.org/reports/FBgn0053451 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33451, 5SrRNA:CR33451" - CR33451 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266580 Gp210 Glycoprotein 210 kDa http://flybase.org/reports/FBgn0266580 protein_coding_gene molecular_function ; GO:0003674 | no biological data available learning or memory ; GO:0007611 | inferred from mutant phenotype protein import into nucleus ; GO:0006606 | inferred from sequence or structural similarity with SGD:S000004736 olfactory learning ; GO:0008355 | inferred from mutant phenotype nuclear pore organization ; GO:0006999 | inferred from sequence or structural similarity with SGD:S000004736 nuclear pore transmembrane ring ; GO:0070762 | inferred from sequence or structural similarity with SGD:S000004736 nuclear pore nuclear basket ; GO:0044615 | inferred from direct assay nuclear pore inner ring ; GO:0044611 | inferred from direct assay nuclear pore ; GO:0005643 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "gp210, CG14467, CG7897, Gp210, GP210, lyadi, gp210[[D]], gp188, Gp188, Dm gp210" IPR008964:Invasin/intimin cell-adhesion fragments CG7897 27-Aug-18 DroID_v2018_08 Drer\nup210 - Cele\npp-12 Xtro\nup210 "Mmus\Nup210l, Mmus\Nup210" "Hsap\NUP210L, Hsap\NUP210" embryonic stage | early FBgn0265200 lncRNA:CR44260 - http://flybase.org/reports/FBgn0265200 non_protein_coding_gene - - - "CR44260, lincRNA.714" - CR44260 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000305 ch-b chilblained b http://flybase.org/reports/FBgn0000305 - gene - - - ch-b - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive" tarsal segment FBgn0003203 rar3 radiation-resistant on 3 http://flybase.org/reports/FBgn0003203 - gene - - - rar3 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0021912 l(2)k11502 lethal (2) k11502 http://flybase.org/reports/FBgn0021912 - gene - - - l(2)k11502 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0260094 2L1923 - http://flybase.org/reports/FBgn0260094 gene - "terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - 2L1923 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" "terminal tracheal cell,somatic clone,embryonic/larval tracheal system" FBgn0014300 l(3)7-19 lethal (3) 7-19 http://flybase.org/reports/FBgn0014300 - gene - - - l(3)7-19 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" macrochaeta FBgn0020782 skarped-wing skarped wing http://flybase.org/reports/FBgn0020782 - gene - - - skarped-wing - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,viable,fertile" wing FBgn0031414 eys eyes shut http://flybase.org/reports/FBgn0031414 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:O97148 extracellular matrix structural constituent ; GO:0005201 | inferred from mutant phenotype" cell morphogenesis ; GO:0000902 | inferred from mutant phenotype temperature compensation of the circadian clock ; GO:0010378 | inferred from mutant phenotype rhabdomere development ; GO:0042052 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from direct assay cell surface ; GO:0009986 | inferred from direct assay non-motile cilium ; GO:0097730 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay cilium ; GO:0005929 | "CG7245, CG15389, CG15388, CT35437, CG33955, eys, spam, mAb21A6, spacemaker, Eys, Spam, 21A6, mAb 21A6, MAb21A6, SPAM, EYS, Eyes Shut" "IPR018097:EGF-like calcium-binding, conserved site, IPR000742:EGF-like domain, IPR001791:Laminin G domain, IPR013032:EGF-like, conserved site, IPR013320:Concanavalin A-like lectin/glucanase domain, IPR000152:EGF-type aspartate/asparagine hydroxylation site, IPR001881:EGF-like calcium-binding domain" CG33955 27-Aug-18 DroID_v2018_08 "Drer\efemp1, Drer\scube1, Drer\scube3, Drer\jag1a, Drer\matn3a, Drer\megf6b, Drer\adgrl4, Drer\fbln1, Drer\zgc:158328, Drer\sned1, Drer\crb2b, Drer\crb2a, Drer\LOC101884253, Drer\fbln7, Drer\sid4, Drer\col28a1a, Drer\svep1, Drer\LOC100535882, Drer\agrn, Drer\LOC100332841, Drer\jag2b, Drer\si:ch73-173h19.3, Drer\lama4, Drer\egflam, Drer\dlb, Drer\col28a1a, Drer\jag2a, Drer\dpy19l1l, Drer\ltbp3, Drer\LOC562634, Drer\jag1b, Drer\adgrf6" - "Cele\agr-1, Cele\F25D7.5, Cele\Y70G10A.2, Cele\T19D12.6" "Xtro\crb2, Xtro\matn4, Xtro\nell1, Xtro\ltbp4, Xtro\hspg2, Xtro\f12, Xtro\jag1, Xtro\egflam, Xtro\hgfac, Xtro\col14a1, Xtro\notch1, Xtro\svep1, Xtro\LOC100491172, Xtro\fbn1, Xtro\agrn" "Mmus\Tdgf1, Mmus\Ltbp4, Mmus\Scube3, Mmus\Habp2, Mmus\Fbn1, Mmus\Dll3, Mmus\Agrn, Mmus\Matn3, Mmus\Sned1, Mmus\Vwce, Mmus\Vwa1, Mmus\Hgfac, Mmus\Egfl7, Mmus\Jag2, Mmus\Scube2, Mmus\Crb2, Mmus\Jag1, Mmus\Ltbp1, Mmus\Hspg2, Mmus\Hmcn2, Mmus\Egflam, Mmus\Fbln7, Mmus\Col22a1, Mmus\Col28a1, Mmus\Dlk2, Mmus\Dlk1, Mmus\F12, Mmus\Svep1, Mmus\Cfc1, Mmus\Vwde, Mmus\Dll4" "Hsap\MATN3, Hsap\SNED1, Hsap\CRB2, Hsap\JAG2, Hsap\JAG1, Hsap\FBLN7, Hsap\SCUBE3, Hsap\COL14A1, Hsap\F12, Hsap\VWCE, Hsap\EGFLAM, Hsap\EYS, Hsap\SVEP1, Hsap\TDGF1, Hsap\CFC1, Hsap\DLK2, Hsap\DLL4, Hsap\CFC1B, Hsap\HSPG2, Hsap\EGFL7, Hsap\LTBP1, Hsap\HGFAC, Hsap\HABP2, Hsap\LOC100996717, Hsap\NOTCH2NL, Hsap\DLK1, Hsap\AGRN, Hsap\DLL3, Hsap\COL22A1, Hsap\VWA1, Hsap\SCUBE2" "locomotor rhythm defective,viable,uncoordinated,heat sensitive,locomotor behavior defective,flightless,neurophysiology defective" "photoreceptor cell,eye photoreceptor cell stalk,rhabdomere,ommatidium,rhabdomere of eye photoreceptor cell,conditional,chemical conditional,eye,ocellus retinula cell,ocellus rhabdomere,rhabdomerehs.PB,mechanosensory neuron,heat sensitive,Johnston organ,scolopale" FBgn0053319 CR33319 - http://flybase.org/reports/FBgn0053319 pseudogene_attribute - - - "CG18078, CR33319" - CR33319 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051562 CR31562 - http://flybase.org/reports/FBgn0051562 pseudogene_attribute - - - "CG15588, CG15587, CG31562, CR31562" - CR31562 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0065905 l(2)SH0193 lethal (2) SH0193 http://flybase.org/reports/FBgn0065905 gene - - - "l(2)SH0193, l(2)SH2 0193" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0039350 jigr1 jing interacting gene regulatory 1 http://flybase.org/reports/FBgn0039350 protein_coding_gene transcription regulatory region DNA binding ; GO:0044212 | inferred from sequence model with InterPro:IPR006578 regulation of gene expression ; GO:0010468 | inferred from sequence model with InterPro:IPR006578 nucleus ; GO:0005634 | inferred from sequence model with InterPro:IPR006578 "bs29f05.y1, jigr1, CG17383, JIGR-1, JIGR1" IPR006578:MADF domain CG17383 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-207i20.3, Drer\LOC100330838, Drer\zgc:152938" - "Cele\madf-3, Cele\madf-8, Cele\madf-2, Cele\madf-9, Cele\madf-10, Cele\madf-4, Cele\madf-5" - - - "neuroanatomy defective,visible,lethal - all die during larval stage,viable,fertile" "embryonic/larval central nervous system,wing,embryonic/larval hemocyte | third instar larval stage" FBgn0005598 yemG3a yema gene 3a http://flybase.org/reports/FBgn0005598 FBgn0004042 gene - - - "yG3a, yT3a, yemG3a" - - 27-Aug-18 DroID_v2018_08 - - - - - - " adult stage && oogenesis stage , embryonic stage | early , embryonic stage | stage <=8 " " ovary

, organism

" FBgn0016852 l(1)N33 lethal (1) N33 http://flybase.org/reports/FBgn0016852 - gene - - - "l(1)N33, N33" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0263653 lncRNA:CR43644 - http://flybase.org/reports/FBgn0263653 non_protein_coding_gene - - - CR43644 - CR43644 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267435 chp chaoptin http://flybase.org/reports/FBgn0267435 protein_coding_gene - microvillus organization ; GO:0032528 | inferred from mutant phenotype rhabdomere development ; GO:0042052 | inferred from genetic interaction with prom homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from direct assay rhabdomere development ; GO:0042052 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay rhabdomere microvillus ; GO:0035996 | inferred from direct assay anchored component of plasma membrane ; GO:0046658 | inferred from direct assay rhabdomere ; GO:0016028 | inferred from direct assay "chp, idl-A, 24B10, mAb24B10, Chp, Mab24B10, MAb 24B10, mAb 24B10, CT5040, MAb24B10, 516, Nsp, CG1744, BSH, mAB24B10, Chaoptin, CHP" "IPR032675:Leucine-rich repeat domain, L domain-like, IPR000225:Armadillo, IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype" CG1744 27-Aug-18 DroID_v2018_08 "Drer\chadla, Drer\lrrcc1, Drer\tlr18, Drer\tlr1, Drer\chadlb, Drer\chad" - "Cele\lron-9, Cele\lron-1, Cele\tol-1, Cele\pan-1, Cele\lron-2" "Xtro\chadl, Xtro\LOC100488097" "Mmus\Chadl, Mmus\Chad, Mmus\Tlr6, Mmus\Lrrcc1, Mmus\Tlr1" "Hsap\TLR6, Hsap\CHADL, Hsap\CHAD, Hsap\LRRCC1, Hsap\TLR10, Hsap\TLR1" larval stage && pupal stage " retina

, photoreceptor cell R1--8

, eye-antennal disc

" " larval stage--adult stage , pupal stage&&adult stage , pupal stage , larval stage&&pupal stage , larval stage && pupal stage " " retina

, medulla

, optic lobe

, photoreceptor cell | presumptive

, eye-antennal disc

, lamina

" FBgn0001806 l(1)Mc39 lethal (1) Mc39 http://flybase.org/reports/FBgn0001806 - gene - - - l(1)Mc39 - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,somatic clone,lethal - all die before end of larval stage,recessive,some die during larval stage" "macrochaeta,somatic clone" FBgn0021944 Coprox Coproporphyrinogen oxidase http://flybase.org/reports/FBgn0021944 "FBgn0021932, FBgn0027909" protein_coding_gene coproporphyrinogen oxidase activity ; GO:0004109 | inferred from sequence or structural similarity coproporphyrinogen oxidase activity ; GO:0004109 | inferred from sequence or structural similarity with UniProtKB:P36551 protein homodimerization activity ; GO:0042803 | inferred from sequence or structural similarity with UniProtKB:P36551 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001260, InterPro:IPR018375 heme biosynthetic process ; GO:0006783 | inferred from sequence or structural similarity with UniProtKB:P36551" mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:P36551 "l(2)k10617, l(2)k11018, CG3433, BcDNA:GM14838, Coprox" "IPR001260:Coproporphyrinogen III oxidase, aerobic, IPR018375:Coproporphyrinogen III oxidase, conserved site" CG3433 27-Aug-18 DroID_v2018_08 Drer\cpox Scer\HEM13 - Xtro\cpox Mmus\Cpox Hsap\CPOX "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,locomotor rhythm defective" FBgn0039128 CG13599 - http://flybase.org/reports/FBgn0039128 protein_coding_gene - regulation of exit from mitosis ; GO:0007096 | inferred from electronic annotation with InterPro:IPR009511 nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR009511 CG13599 IPR009511:Mad1/Cdc20-bound-Mad2 binding protein CG13599 27-Aug-18 DroID_v2018_08 Drer\mad2l1bp - - - Mmus\Mad2l1bp Hsap\MAD2L1BP "viable,fertile,visible" trichogen cell FBgn0032221 Schip1 Schwannomin interacting protein 1 http://flybase.org/reports/FBgn0032221 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q0KHQ5 positive regulation of protein serine/threonine kinase activity ; GO:0071902 | inferred from mutant phenotype positive regulation of hippo signaling ; GO:0035332 | inferred from mutant phenotype hippo signaling ; GO:0035329 | inferred from mutant phenotype negative regulation of growth ; GO:0045926 | inferred from mutant phenotype adherens junction ; GO:0005912 | inferred from direct assay apical plasma membrane ; GO:0016324 | inferred from direct assay "CG5375, Schip1" IPR015649:Schwannomin interacting protein 1 CG5375 27-Aug-18 DroID_v2018_08 "Drer\zgc:153615, Drer\schip1" - Cele\F35H12.1 Xtro\schip1 "Mmus\Schip1, Mmus\Gm21949" "Hsap\SCHIP1, Hsap\IQCJ-SCHIP1" viable FBgn0040589 CG13839 - http://flybase.org/reports/FBgn0040589 protein_coding_gene - - - CG13839 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0029054 l(1)G0453 lethal (1) G0453 http://flybase.org/reports/FBgn0029054 gene - - - l(1)G0453 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0012027 tRNA:Tyr-GTA-1-5 transfer RNA:Tyrosine-GTA 1-5 http://flybase.org/reports/FBgn0012027 "FBgn0003849, FBgn0012014, FBgn0051552, FBgn0060002" tRNA_gene UAC codon-amino acid adaptor activity ; GO:0033410 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033410 cytosol ; GO:0005829 | inferred by curator from GO:0033410 "Tyr-tRNA, tRNA-Tyr, 85Ad, tRNA[Tyr][[1gamma]], AE002708.trna60-TyrGTA, tRNA:Y, tRNA:Y:GTA:AE002708-d, CR31552, tRNA:tyr1:85Ad, tRNA[Tyr], chr3R.trna66-TyrGTA, tRNA-Tyr-GTA-1-5, tRNA:Tyr-GTA-1-5, tRNA:Y1:85Ad, UAC" - CR31552 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0069299 ali alice http://flybase.org/reports/FBgn0069299 gene molecular_function ; GO:0003674 | no biological data available "anterior/posterior axis specification, embryo ; GO:0008595 | inferred from mutant phenotype" cellular_component ; GO:0005575 | no biological data available ali - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,germline clone,non-rescuable maternal effect,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "filzkorper,ectopic,germline clone,maternal effect" FBgn0043588 EK3-3 EK3-3 http://flybase.org/reports/FBgn0043588 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available EK3-3 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,visible,dominant" "eye,wing vein" FBgn0267593 CR45931 - http://flybase.org/reports/FBgn0267593 pseudogene_attribute - - - "CR45931, CG40245" - CR45931 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0044446 EP851 EP851 http://flybase.org/reports/FBgn0044446 gene - - - EP851 - - 27-Aug-18 DroID_v2018_08 - - - - - - neuroanatomy defective "intersegmental nerve,anterior fascicle & synapse" FBgn0031771 ND-51 NADH dehydrogenase (ubiquinone) 51 kDa subunit http://flybase.org/reports/FBgn0031771 protein_coding_gene "NADH dehydrogenase (ubiquinone) activity ; GO:0008137 | inferred from electronic annotation with InterPro:IPR001949 NAD binding ; GO:0051287 | inferred from electronic annotation with InterPro:IPR011537 4 iron, 4 sulfur cluster binding ; GO:0051539 | inferred from electronic annotation with InterPro:IPR001949, InterPro:IPR011537, InterPro:IPR019575 FMN binding ; GO:0010181 | inferred from electronic annotation with InterPro:IPR001949, InterPro:IPR011537 NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:P49821" "mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with UniProtKB:P49821" mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:P49821 "CG9140, NUBM, ND-51, ND51" "IPR001949:NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site, IPR011537:NADH ubiquinone oxidoreductase, F subunit, IPR011538:NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain, IPR019554:Soluble ligand binding domain, IPR019575:NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain" CG9140 27-Aug-18 DroID_v2018_08 "Drer\ndufv1, Drer\zgc:123290" - Cele\nuo-1 Xtro\ndufv1 Mmus\Ndufv1 Hsap\NDUFV1 "lethal,RU486 conditional,developmental rate defective,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0266096 lncRNA:CR44833 - http://flybase.org/reports/FBgn0266096 non_protein_coding_gene - - - "CR44833, Mgn94020" - CR44833 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031673 CG31650 - http://flybase.org/reports/FBgn0031673 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 Golgi organization ; GO:0007030 | inferred from mutant phenotype endoplasmic reticulum ; GO:0005783 | inferred from direct assay "CG9112, CG31650, RCN2" "IPR002048:EF-hand domain, IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site" CG31650 27-Aug-18 DroID_v2018_08 "Drer\rcn2, Drer\calua, Drer\rcn1, Drer\rcn3" - "Cele\calu-2, Cele\calu-1" "Xtro\rcn2, Xtro\calu, Xtro\rcn3, Xtro\rcn1" "Mmus\Rcn1, Mmus\Rcn3, Mmus\Rcn2, Mmus\Calu" "Hsap\RCN2, Hsap\RCN1, Hsap\RCN3, Hsap\CALU" viable FBgn0050130 CG30130 - http://flybase.org/reports/FBgn0050130 protein_coding_gene - - - CG30130 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263764 lncRNA:CR43681 - http://flybase.org/reports/FBgn0263764 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "Dm_2L:52920, lincRNA.108, CR43681, CG43681" - CR43681 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0010189 tu-47 tu-47 http://flybase.org/reports/FBgn0010189 - gene - - - tu-47 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266003 lncRNA:CR44777 - http://flybase.org/reports/FBgn0266003 non_protein_coding_gene - - - CR44777 - CR44777 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002323 l(3)86Fb lethal (3) 86Fb http://flybase.org/reports/FBgn0002323 - gene - - - "l(3)ck2, l(3)86Fb" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0261671 tweek tweek http://flybase.org/reports/FBgn0261671 protein_coding_gene molecular_function ; GO:0003674 | no biological data available synaptic vesicle endocytosis ; GO:0048488 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "tweek, CG4841, CG15133, CG15134, CG42555, CG42706, Tweek" "IPR018863:Fragile site-associated protein, C-terminal, IPR033616:Protein KIAA1109" CG42555 27-Aug-18 DroID_v2018_08 Drer\si:ch211-233a24.2 Scer\CSF1 Cele\lpd-3 Xtro\kiaa1109 Mmus\4932438A13Rik Hsap\KIAA1109 FBgn0036168 CG7512 - http://flybase.org/reports/FBgn0036168 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 "transcription, DNA-templated ; GO:0006351 | inferred from biological aspect of ancestor with PANTHER:PTN000278753 regulation of neuron differentiation ; GO:0045664 | inferred from biological aspect of ancestor with PANTHER:PTN000278753" - CG7512 IPR013087:Zinc finger C2H2-type CG7512 27-Aug-18 DroID_v2018_08 Drer\casz1 - - - Mmus\Casz1 Hsap\CASZ1 viable FBgn0037992 CG4702 - http://flybase.org/reports/FBgn0037992 protein_coding_gene - - - "CG4702, 4702" IPR006631:Protein of unknown function DM4/12 CG4702 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" FBgn0039722 Capa Capability http://flybase.org/reports/FBgn0039722 protein_coding_gene myostimulatory hormone activity ; GO:0016084 | inferred from mutant phenotype neuropeptide hormone activity ; GO:0005184 | inferred from mutant phenotype receptor binding ; GO:0005102 | inferred from sequence or structural similarity neuropeptide hormone activity ; GO:0005184 | non-traceable author statement diuretic hormone activity ; GO:0008613 | inferred from direct assay neuropeptide receptor binding ; GO:0071855 | inferred from physical interaction with PK1-R neuropeptide hormone activity ; GO:0005184 | inferred from sequence or structural similarity neuropeptide receptor binding ; GO:0071855 | inferred from physical interaction with CapaR epithelial fluid transport ; GO:0042045 | inferred from direct assay cation transport ; GO:0006812 | traceable author statement neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay neuropeptide signaling pathway ; GO:0007218 | inferred from expression pattern neuropeptide signaling pathway ; GO:0007218 | inferred from sequence or structural similarity positive regulation of cytosolic calcium ion concentration ; GO:0007204 | inferred from direct assay nitric oxide-cGMP-mediated signaling pathway ; GO:0038060 | inferred from direct assay neuropeptide signaling pathway ; GO:0007218 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from sequence model extracellular space ; GO:0005615 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay "CAP[[2b]], capa-1, capa-2, capa-3, Drm-PK-1, CAP2b-3, CG15520, Drm-PVK-2, Drm-PVK-1, CAP2B-3, CAP2B-2, CAP2B-1, Drm-CAP-2, Drm-CAP-1, CAP2b, CAP2b-2, CAP2b-1, pyrokinin/PBAN-like, CAP2B/pyrokinin, Drm-MT, Drm-CAP2b/MT, Cap-2b, CAP-2b, Capa-1, Capa-2, CAPA, Drm-PVK, CAP, Capa, capa, capa 2, Cap-1, Cap-2, Cap-3, Drm-capa-1, PVK-2, Drm-PK, CAPA-PVK/PK, CAPA-PVK-1, CAPA-PVK-2, CAPA-PK, CPPB, Drome-capa-1" - CG15520 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0051858 t-cup tetleys-cup http://flybase.org/reports/FBgn0051858 protein_coding_gene heme binding ; GO:0020037 | inferred from biological aspect of ancestor with PANTHER:PTN000031653 biological_process ; GO:0008150 | no biological data available membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN000031541 endomembrane system ; GO:0012505 | inferred from biological aspect of ancestor with PANTHER:PTN000031541 "t-cup, CG31858, cup" IPR001199:Cytochrome b5-like heme/steroid binding domain CG31858 27-Aug-18 DroID_v2018_08 "Drer\pgrmc2, Drer\pgrmc1, Drer\nenf" Scer\DAP1 Cele\vem-1 "Xtro\pgrmc1, Xtro\nenf, Xtro\pgrmc2" "Mmus\Pgrmc2, Mmus\Pgrmc1, Mmus\Nenf" "Hsap\NENF, Hsap\PGRMC1, Hsap\PGRMC2" viable DRSC01254 I 1.741319522 1.652263905 0.622614721 1.084253099 -0.24252598 -0.043542791 FBgn0260985 RfC4 Replication factor C subunit 4 http://flybase.org/reports/FBgn0260985 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959 DNA clamp loader activity ; GO:0003689 | contributes_to inferred from sequence or structural similarity with SGD:S000005454 DNA clamp loader activity ; GO:0003689 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000186208 DNA binding ; GO:0003677 | inferred from mutant phenotype sister chromatid cohesion ; GO:0007062 | inferred from sequence or structural similarity with SGD:S000005454 DNA strand elongation involved in DNA replication ; GO:0006271 | traceable author statement mitotic chromosome condensation ; GO:0007076 | inferred from mutant phenotype DNA repair ; GO:0006281 | traceable author statement neurogenesis ; GO:0022008 | inferred from mutant phenotype leading strand elongation ; GO:0006272 | inferred from sequence or structural similarity with SGD:S000005454 DNA damage checkpoint ; GO:0000077 | inferred from mutant phenotype female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype DNA replication checkpoint ; GO:0000076 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype DNA replication ; GO:0006260 | inferred from mutant phenotype DNA replication ; GO:0006260 | traceable author statement lateral inhibition ; GO:0046331 | inferred from mutant phenotype DNA replication factor C complex ; GO:0005663 | inferred from biological aspect of ancestor with PANTHER:PTN000186208 nucleus ; GO:0005634 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay DNA replication factor C complex ; GO:0005663 | inferred from sequence or structural similarity with SGD:S000005454 Elg1 RFC-like complex ; GO:0031391 | inferred from direct assay "RfC40, RfC4, l(3)Rfc4, CG14999, l(3)e20, DmRFC4, Rfc4, l(3)dsl-1, l(3)dsl1, l(3)A1, l(3)SG13, 154910_at, Rfc40, l(3)64Ai, rfc4, l(3)rfc40, rfc[40], l(3)SH17, rfc, BEST:GH24992, rfc40, RFC40" "IPR003593:AAA+ ATPase domain, IPR008921:DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal, IPR013748:Replication factor C, C-terminal, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR003959:ATPase, AAA-type, core" CG14999 27-Aug-18 DroID_v2018_08 "Drer\rfc2, Drer\rfc5" Scer\RFC4 "Cele\F44B9.8, Cele\rfc-2, Cele\rfc-4" "Xtro\rfc2, Xtro\rfc5, Xtro\rfc4" "Mmus\Rfc5, Mmus\Rfc2, Mmus\Rfc4" "Hsap\RFC5, Hsap\RFC2" embryonic stage FBgn0067319 CG40450 - http://flybase.org/reports/FBgn0067319 protein_coding_gene - - - CG40450 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005455 l(1)v451 lethal (1) v451 http://flybase.org/reports/FBgn0005455 - gene - - - "l(1)451, l(1)v451" - - 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,lethal,male,lethal - all die before end of larval stage,maternal effect,some die during larval stage" "egg chamber,germline clone,maternal effect" FBgn0261625 GLS Glutaminase http://flybase.org/reports/FBgn0261625 protein_coding_gene glutaminase activity ; GO:0004359 | inferred from sequence or structural similarity with UniProtKB:O94925 glutaminase activity ; GO:0004359 | inferred from biological aspect of ancestor with PANTHER:PTN000283994 imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype glutamate biosynthetic process ; GO:0006537 | inferred from biological aspect of ancestor with PANTHER:PTN000283994 glutamine catabolic process ; GO:0006543 | inferred from biological aspect of ancestor with PANTHER:PTN000283994 glutamine metabolic process ; GO:0006541 | inferred from sequence or structural similarity with UniProtKB:O94925 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:O94925 mitochondrial matrix ; GO:0005759 | inferred from biological aspect of ancestor with PANTHER:PTN000283995 "GLS, CG42708, CG8772, CG8872" "IPR015868:Glutaminase, IPR002110:Ankyrin repeat, IPR012338:Beta-lactamase/transpeptidase-like, IPR020683:Ankyrin repeat-containing domain" CG42708 27-Aug-18 DroID_v2018_08 "Drer\glsl, Drer\glsb, Drer\gls2a, Drer\si:dkey-102c8.2, Drer\gls2b, Drer\glsa" - "Cele\glna-3, Cele\glna-2, Cele\glna-1" "Xtro\gls, Xtro\gls2" "Mmus\Gls, Mmus\Gls2" "Hsap\GLS, Hsap\GLS2" viable FBgn0250910 Octbeta3R Octopamine beta3 receptor http://flybase.org/reports/FBgn0250910 protein_coding_gene octopamine receptor activity ; GO:0004989 | inferred from sequence or structural similarity with UniProtKB:Q9VCZ3 inferred from direct assay G-protein coupled amine receptor activity ; GO:0008227 | inferred from sequence or structural similarity adenylate cyclase-activating G-protein coupled receptor signaling pathway ; GO:0007189 | inferred from sequence or structural similarity with UniProtKB:Q9VCZ3 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from direct assay positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway ; GO:0010579 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "Octbeta3R, CG7078, DmOctbeta3R, CG33959, DmCG7078, CG31350, CG31351, CG31348, OctBeta3, CG18554, anon-WO0170980.188, anon-WO0170980.187, CG34055, CG42244, octRbeta3, Octb3R, octbeta3R" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG42244 27-Aug-18 DroID_v2018_08 "Drer\taar12e, Drer\taar14b, Drer\taar10c, Drer\si:ch211-139n6.11, Drer\taar14e, Drer\taar20j, Drer\taar12h, Drer\taar20b, Drer\taar13c, Drer\taar19o, Drer\taar13b, Drer\taar20q, Drer\taar19c, Drer\taar19p, Drer\taar20u, Drer\taar14g, Drer\taar12f, Drer\taar20x, Drer\taar12i, Drer\taar15, Drer\taar14i, Drer\taar20n, Drer\taar18e, Drer\taar20r, Drer\si:dkey-246e3.4, Drer\taar13d, Drer\taar20a, Drer\taar12a, Drer\taar10a, Drer\taar10d, Drer\taar1b, Drer\taar10, Drer\taar12g, Drer\taar19e, Drer\taar11, Drer\taar20o, Drer\taar14l, Drer\taar18g, Drer\taar12j, Drer\taar14j, Drer\taar19k, Drer\zgc:153137, Drer\taar14f, Drer\taar20c1, Drer\taar18c, Drer\taar19r, Drer\taar14h, Drer\taar20c, Drer\taar13e, Drer\taar20h, Drer\taar14a, Drer\LOC100149223, Drer\htr4, Drer\taar12c, Drer\taar20w, Drer\taar20i, Drer\taar19b, Drer\taar64, Drer\taar18a, Drer\taar12b, Drer\taar14d, Drer\taar20l, Drer\taar12m, Drer\taar10b, Drer\si:ch211-238p8.35, Drer\taar16f, Drer\taar19d, Drer\hrh2a, Drer\taar19m, Drer\taar19g, Drer\taar18b, Drer\hrh2b, Drer\taar20t, Drer\si:dkey-247m21.3" - "Cele\npr-1, Cele\F59D12.1, Cele\ser-5, Cele\C01F1.4" "Xtro\htr4, Xtro\hrh2" "Mmus\Taar7e, Mmus\Htr4, Mmus\Hrh2, Mmus\Taar7a, Mmus\Taar6, Mmus\Taar7f, Mmus\Taar7d, Mmus\Taar9, Mmus\Taar2, Mmus\Taar1, Mmus\Taar8a, Mmus\Taar8b, Mmus\Taar7b, Mmus\Taar5, Mmus\Taar8c, Mmus\Taar4, Mmus\Taar3" "Hsap\TAAR8, Hsap\HTR4, Hsap\TAAR6, Hsap\TAAR9, Hsap\TAAR1, Hsap\TAAR2, Hsap\TAAR5, Hsap\HRH2" """DRSC15351, DRSC24019"" " IEK FBgn0066126 E(sda)H E(sda)H http://flybase.org/reports/FBgn0066126 gene - - - "E(sda)H, Line H" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0036560 CG5895 - http://flybase.org/reports/FBgn0036560 protein_coding_gene phosphoric diester hydrolase activity ; GO:0008081 | inferred from electronic annotation with InterPro:IPR017946 lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR017946 - CG5895 "IPR017946:PLC-like phosphodiesterase, TIM beta/alpha-barrel domain" CG5895 27-Aug-18 DroID_v2018_08 "Drer\plcxd1, Drer\LOC100151335, Drer\zgc:112023, Drer\zgc:64065, Drer\si:dkey-66a8.7, Drer\plcxd2, Drer\plcxd3" - Cele\F38E9.1 "Xtro\plcxd3, Xtro\plcxd2, Xtro\plcxd1" "Mmus\Plcxd1, Mmus\Plcxd2, Mmus\Plcxd3" "Hsap\PLCXD1, Hsap\PLCXD2, Hsap\PLCXD3" "viable,fertile" FBgn0084022 CG41461 - http://flybase.org/reports/FBgn0084022 protein_coding_gene - - - CG41461 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0052104 CG32104 - http://flybase.org/reports/FBgn0052104 protein_coding_gene molecular_function ; GO:0003674 | no biological data available transcription from RNA polymerase II promoter ; GO:0006366 | inferred from sequence or structural similarity with SGD:S000002935 transcription from RNA polymerase II promoter ; GO:0006366 | inferred from biological aspect of ancestor with PANTHER:PTN000486254 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000002935 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000486254 "CG14124, anon-69Ag, CG14123, CG32104" "IPR016024:Armadillo-type fold, IPR013929:RNA polymerase II-associated protein 1, C-terminal, IPR013930:RNA polymerase II-associated protein 1, N-terminal, IPR011989:Armadillo-like helical" CG32104 27-Aug-18 DroID_v2018_08 Drer\rpap1 Scer\RBA50 Cele\F56B3.4 Xtro\rpap1 Mmus\Rpap1 Hsap\RPAP1 "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0065963 l(2)SH0026 lethal (2) SH0026 http://flybase.org/reports/FBgn0065963 gene - - - "l(2)SH0026, l(2)SH2 0026" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0032065 CG12438 - http://flybase.org/reports/FBgn0032065 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12438 - CG12438 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0025115 Acyp Acylphosphatase http://flybase.org/reports/FBgn0025115 - protein_coding_gene acylphosphatase activity ; GO:0003998 | inferred from direct assay acylphosphatase activity ; GO:0003998 | inferred from sequence or structural similarity - - "AcPDro, CG16870, ACPDro, BG:DS00180.1, Acyp" "IPR001792:Acylphosphatase-like domain, IPR017968:Acylphosphatase, conserved site, IPR020456:Acylphosphatase" CG16870 27-Aug-18 DroID_v2018_08 "Drer\acyp2, Drer\acyp1" - - "Xtro\acyp1, Xtro\acyp2" "Mmus\Acyp2, Mmus\Acyp1" "Hsap\ACYP1, Hsap\ACYP2" FBgn0265397 EP2124 - http://flybase.org/reports/FBgn0265397 gene - - - EP2124 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005702 l(1)TK105 lethal (1) TK105 http://flybase.org/reports/FBgn0005702 - gene - - - "l105, l(1)TK105" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" "eye,lamina,optic lobe" FBgn0065165 l(3)SH034 lethal (3) SH034 http://flybase.org/reports/FBgn0065165 gene - - - "l(3)SH034, l(2)SH3 034" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0263517 mir-4976 mir-4976 stem loop http://flybase.org/reports/FBgn0263517 miRNA_gene - - - "mir-4976, CR43502, dme-mir-4976" - CR43502 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0042681 Rt1b\RTase Rt1b element RTase http://flybase.org/reports/FBgn0042681 transposable_element_gene - - - "ORF2, Waldo-A\RTase, Rt1b\RTase" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002175 chem lethal (3) 5G83 http://flybase.org/reports/FBgn0002175 - gene - - - l(3)5G83 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal dorsal closure embryo FBgn0267003 lncRNA:CR45447 - http://flybase.org/reports/FBgn0267003 non_protein_coding_gene - - - CR45447 - CR45447 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0052115 CG32115 - http://flybase.org/reports/FBgn0052115 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE40923, CG32115" "IPR032675:Leucine-rich repeat domain, L domain-like" CG32115 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0086266 Vm26Ac Vitelline membrane 26Aac http://flybase.org/reports/FBgn0086266 protein_coding_gene structural constituent of vitelline membrane ; GO:0008316 | inferred from sequence model vitelline membrane formation involved in chorion-containing eggshell formation ; GO:0007305 | inferred from sequence model egg coat ; GO:0035805 | inferred from sequence model chorion ; GO:0042600 | inferred from direct assay "CG13997, TU-3, fc20, Vm26Ac, Fcp26Ac, fc 20, VM26Ac" IPR013135:Vitelline membrane cysteine-rich domain CG13997 27-Aug-18 DroID_v2018_08 - Scer\NUP159 - - - - oogenesis stage | stage S8-11 FBgn0266795 asRNA:CR45257 - http://flybase.org/reports/FBgn0266795 non_protein_coding_gene - - - CR45257 - CR45257 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259426 EP-1152.1 - http://flybase.org/reports/FBgn0259426 gene - - - EP-1152.1 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing vein,wing" FBgn0085739 CR40507 - http://flybase.org/reports/FBgn0085739 rRNA_gene - - - CR40507 - CR40507 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0044082 E(rst)H253 E(rst)H253 http://flybase.org/reports/FBgn0044082 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "H253, E(rst)H253" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039023 CG4723 - http://flybase.org/reports/FBgn0039023 protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR018497" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR008753, InterPro:IPR018497" - CG4723 "IPR000718:Peptidase M13, IPR008753:Peptidase M13, N-terminal domain, IPR018497:Peptidase M13, C-terminal domain, IPR024079:Metallopeptidase, catalytic domain" CG4723 27-Aug-18 DroID_v2018_08 "Drer\ece1, Drer\ece2b, Drer\mmel1, Drer\phex" - "Cele\nep-12, Cele\nep-10, Cele\nep-23, Cele\nep-3, Cele\nep-24, Cele\nep-5, Cele\nep-8, Cele\nep-18, Cele\nep-20, Cele\nep-9, Cele\nep-7, Cele\nep-16, Cele\nep-26, Cele\nep-17, Cele\nep-13, Cele\nep-21, Cele\nep-19, Cele\nep-6" "Xtro\mmel1, Xtro\ecel1, Xtro\ece2, Xtro\ece1" "Mmus\Mmel1, Mmus\Ecel1, Mmus\Phex, Mmus\Ece2, Mmus\Kel, Mmus\Ece1, Mmus\Mme" "Hsap\ECE2, Hsap\KEL, Hsap\MMEL1, Hsap\PHEX, Hsap\MME, Hsap\ECEL1, Hsap\ECE1" viable FBgn0051603 tRNA:Asp-GTC-1-5 transfer RNA:Aspartic acid-GTC 1-5 http://flybase.org/reports/FBgn0051603 tRNA_gene - - - "tRNA:asp2:29E, tRNA:D2:29E, CR31603, tRNA[[Asp]], tRNA[Asp-GTC], chr2L.trna13-AspGTC, tRNA:Asp-GTC-1-5, tRNA:CR31603, tRNA-Asp-GTC-1-5, GAC" - CR31603 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0063644 CE3-2 "Calcineurin enhancer, chromosome 3, group 2" http://flybase.org/reports/FBgn0063644 gene - - - CE3-2 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0002374 l(3)91Ff lethal (3) 91Ff http://flybase.org/reports/FBgn0002374 - gene - - - "l(3)BE91, l(3)BE90, l(3)91Ff" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0027085 LeuRS-m "Leucyl-tRNA synthetase, mitochondrial" http://flybase.org/reports/FBgn0027085 FBgn0035576 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001412, InterPro:IPR002300, InterPro:IPR002302, InterPro:IPR009080, InterPro:IPR015413 aminoacyl-tRNA editing activity ; GO:0002161 | inferred from electronic annotation with InterPro:IPR009008 leucine-tRNA ligase activity ; GO:0004823 | traceable author statement leucine-tRNA ligase activity ; GO:0004823 | inferred from sequence or structural similarity with UniProtKB:Q15031" leucyl-tRNA aminoacylation ; GO:0006429 | traceable author statement leucyl-tRNA aminoacylation ; GO:0006429 | inferred from sequence or structural similarity with UniProtKB:Q15031 mitochondrial translation ; GO:0032543 | inferred from biological aspect of ancestor with PANTHER:PTN000236416 mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:Q15031 mitochondrion ; GO:0005739 | traceable author statement "LeuRS, LRS, CG7479, Aats-leu, LeuRS-m" "IPR001412:Aminoacyl-tRNA synthetase, class I, conserved site, IPR002302:Leucine-tRNA ligase, IPR009080:Aminoacyl-tRNA synthetase, class Ia, anticodon-binding, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold, IPR015413:Methionyl/Leucyl tRNA synthetase, IPR009008:Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain, IPR002300:Aminoacyl-tRNA synthetase, class Ia, IPR013155:Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding" CG7479 27-Aug-18 DroID_v2018_08 Drer\lars2 Scer\NAM2 Cele\lars-2 Xtro\lars2 Mmus\Lars2 Hsap\LARS2 embryonic stage

ubiquitous "viable,visible,decreased cell size,cell autonomous,somatic clone" "trichogen cell,lysosome & larval fat body | somatic clone | cell autonomous" FBgn0266198 lncRNA:CR44893 - http://flybase.org/reports/FBgn0266198 non_protein_coding_gene - - - "CR44893, lincRNA.1004" - CR44893 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001327 ks-1 male fertility factor ks1 http://flybase.org/reports/FBgn0001327 - gene - - - "Sms1, ks-1" - - 27-Aug-18 DroID_v2018_08 - - - - - - male sterile FBgn0023470 anon-30Fd anon-30Fd http://flybase.org/reports/FBgn0023470 - gene - - - anon-30Fd - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085520 CR40801 - http://flybase.org/reports/FBgn0085520 pseudogene_attribute - - - "CG40801, CR40801" - CR40801 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0010926 l(3)07882 lethal (3) 07882 http://flybase.org/reports/FBgn0010926 FBgn0038517 protein_coding_gene snoRNA binding ; GO:0030515 | inferred from sequence or structural similarity with UniProtKB:Q99207 ribosomal small subunit biogenesis ; GO:0042274 | inferred from sequence or structural similarity with UniProtKB:Q99207 rRNA processing ; GO:0006364 | inferred from sequence or structural similarity with UniProtKB:Q99207 maturation of SSU-rRNA ; GO:0030490 | inferred from biological aspect of ancestor with PANTHER:PTN000573053 nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000573053 small-subunit processome ; GO:0032040 | inferred from biological aspect of ancestor with PANTHER:PTN000573053 Noc4p-Nop14p complex ; GO:0030692 | inferred from biological aspect of ancestor with PANTHER:PTN000573053 nucleolus ; GO:0005730 | inferred from sequence or structural similarity with UniProtKB:Q99207 "CG5824, l(3)07882" IPR007276:Nucleolar protein 14 CG5824 27-Aug-18 DroID_v2018_08 Drer\nop14 Scer\NOP14 Cele\Y48G1A.4 Xtro\nop14 Mmus\Nop14 Hsap\NOP14 "partially lethal - majority die,recessive,lethal" FBgn0038145 Droj2 DnaJ-like-2 http://flybase.org/reports/FBgn0038145 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR012724 unfolded protein binding ; GO:0051082 | inferred from electronic annotation with InterPro:IPR001305, InterPro:IPR008971, InterPro:IPR012724 heat shock protein binding ; GO:0031072 | inferred from electronic annotation with InterPro:IPR001305" "protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR008971, InterPro:IPR012724 response to heat ; GO:0009408 | inferred from electronic annotation with InterPro:IPR012724 neurogenesis ; GO:0022008 | inferred from mutant phenotype" cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN001531327 "anon-WO0118547.404, CG8863, Droj2, DROJ2, DnaJL2A, DnaJ-like-2" "IPR001305:Heat shock protein DnaJ, cysteine-rich domain, IPR001623:DnaJ domain, IPR002939:Chaperone DnaJ, C-terminal, IPR008971:HSP40/DnaJ peptide-binding, IPR018253:DnaJ domain, conserved site, IPR012724:Chaperone DnaJ" CG8863 27-Aug-18 DroID_v2018_08 "Drer\dnaja2l, Drer\dnaja1, Drer\dnajc16, Drer\dnaja, Drer\dnaja2, Drer\dnajc16l" "Scer\SIS1, Scer\XDJ1, Scer\YDJ1, Scer\SCJ1, Scer\APJ1" "Cele\dnj-3, Cele\dnj-19, Cele\dnj-14, Cele\dnj-8, Cele\dnj-12" "Xtro\dnaja1, Xtro\dnaja4.2, Xtro\dnaja4.1, Xtro\dnaja2" "Mmus\Dnajc16, Mmus\Dnaja4, Mmus\Dnaja1, Mmus\Dnaja2" "Hsap\DNAJA2, Hsap\DNAJA1, Hsap\DNAJA4, Hsap\DNAJC16" "lethal,neuroanatomy defective" ganglion mother cell DRSC16450 I 1.533035775 2.653205633 -1.252964288 0.49932945 -1.285512664 -0.083718323 FBgn0037417 Osi10 Osiris 10 http://flybase.org/reports/FBgn0037417 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of plasma membrane ; GO:0005887 | inferred from sequence model "Osi10, CG15593" IPR012464:Protein of unknown function DUF1676 CG15593 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC12279 I 1.427297196 1.537261355 0.567794344 0.155738551 0.54609664 -0.093914367 FBgn0284220 Top2 Topoisomerase 2 http://flybase.org/reports/FBgn0284220 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001154, InterPro:IPR001241, InterPro:IPR002205, InterPro:IPR013506, InterPro:IPR013757, InterPro:IPR013758, InterPro:IPR013759, InterPro:IPR013760, InterPro:IPR018522 DNA binding ; GO:0003677 | inferred from direct assay DNA topoisomerase type II (ATP-hydrolyzing) activity ; GO:0003918 | inferred from direct assay mRNA binding ; GO:0003729 | inferred from direct assay satellite DNA binding ; GO:0003696 | inferred from direct assay rDNA binding ; GO:0000182 | inferred from direct assay four-way junction DNA binding ; GO:0000400 | inferred from direct assay chromatin binding ; GO:0003682 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with barr inferred from physical interaction with ph-p" chromosome condensation ; GO:0030261 | inferred from mutant phenotype meiotic nuclear division ; GO:0007126 | traceable author statement mitotic nuclear division ; GO:0007067 | traceable author statement chromatin silencing ; GO:0006342 | inferred from direct assay DNA topological change ; GO:0006265 | inferred from direct assay metaphase plate congression ; GO:0051310 | inferred from direct assay sister chromatid segregation ; GO:0000819 | inferred from direct assay mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs mitotic chromosome condensation ; GO:0007076 | inferred from mutant phenotype mitotic sister chromatid segregation ; GO:0000070 | inferred from mutant phenotype male meiosis chromosome segregation ; GO:0007060 | inferred from mutant phenotype CHRAC ; GO:0008623 | inferred from direct assay CHRAC ; GO:0008623 | NOT inferred from direct assay ACF complex ; GO:0016590 | NOT inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay chromosome ; GO:0005694 | inferred from direct assay condensed chromosome ; GO:0000793 | colocalizes_with inferred from direct assay "suo, Top2, CG10223, TopoII, TOP2, topoII, topo II, dTopoII, CHRAC, TOPOII, top2, dCHRAC, Topo II, TopII, TOPO II" "IPR034157:DNA topoisomerase 2, TOPRIM domain, IPR031660:C-terminal associated domain of TOPRIM, IPR018522:DNA topoisomerase, type IIA, conserved site, IPR006171:TOPRIM domain, IPR001154:DNA topoisomerase II, eukaryotic-type, IPR001241:DNA topoisomerase, type IIA, IPR002205:DNA topoisomerase, type IIA, subunit A/C-terminal, IPR003594:Histidine kinase-like ATPase, C-terminal domain, IPR013506:DNA topoisomerase, type IIA, subunit B, domain 2, IPR013758:DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta, IPR013759:DNA topoisomerase, type IIA, central domain, IPR013760:DNA topoisomerase, type IIA-like domain, IPR013757:Type IIA DNA topoisomerase subunit A, alpha-helical domain, IPR020568:Ribosomal protein S5 domain 2-type fold, IPR024946:Arginine repressor C-terminal-like domain, IPR014721:Ribosomal protein S5 domain 2-type fold, subgroup" CG10223 27-Aug-18 DroID_v2018_08 "Drer\top2b, Drer\top2a" Scer\TOP2 "Cele\cin-4, Cele\R05D3.12, Cele\top-2" "Xtro\top2b, Xtro\top2a" "Mmus\Top2b, Mmus\Top2a" "Hsap\TOP2B, Hsap\TOP2A" "neuroanatomy defective,somatic clone,lethal,recessive,partially lethal - majority die,male fertile,female sterile,heat sensitive,male sterile,viable,lethal - all die before end of first instar larval stage,lethal - all die before end of second instar larval stage,small body,developmental rate defective,lethal - all die during first instar larval stage,visible" "adult mushroom body,somatic clone,imaginal disc,heat sensitive,embryonic/larval brain,polytene chromosomeExel9043),ovary,female germline stem cell,embryonic/larval salivary gland,embryonic/larval central nervous system,mesothoracic tergum" DRSC03459 I 0.589767748 1.986121485 -0.956562385 -0.369826165 -1.008581182 -0.061813505 FBgn0039411 dysf dysfusion http://flybase.org/reports/FBgn0039411 protein_coding_gene "protein heterodimerization activity ; GO:0046982 | traceable author statement RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN000548738 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with ss protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with tgo transcription factor activity, sequence-specific DNA binding ; GO:0003700 | contributes_to inferred from physical interaction with tgo sequence-specific DNA binding ; GO:0043565 | contributes_to inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | contributes_to inferred from direct assay sequence-specific DNA binding ; GO:0043565 | inferred from direct assay" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from sequence or structural similarity with ss positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay imaginal disc-derived leg joint morphogenesis ; GO:0016348 | inferred from mutant phenotype branch fusion, open tracheal system ; GO:0035147 | inferred from mutant phenotype morphogenesis of an epithelial fold ; GO:0060571 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from direct assay epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype Notch signaling pathway ; GO:0007219 | inferred from direct assay branch fusion, open tracheal system ; GO:0035147 | inferred from expression pattern inferred from mutant phenotype" "nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | inferred by curator from GO:0003700,GO:0043565 protein complex ; GO:0043234 | inferred from physical interaction with tgo nucleus ; GO:0005634 | inferred by curator from GO:0003700" "Dys, CG14554, CG12561, CG14553, CG14552, CG32474, dNXFL, dysf, dys, NXFL" "IPR000014:PAS domain, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG32474 27-Aug-18 DroID_v2018_08 "Drer\npas4b, Drer\npas4a" - "Cele\cky-1, Cele\ahr-1" Xtro\npas4 Mmus\Npas4 "Hsap\SIM2, Hsap\NPAS4" "lethal,recessive" "embryonic/larval ganglionic branch,embryonic/larval lateral trunk,embryonic/larval dorsal branch,embryonic/larval dorsal trunk,ganglionic branch primordium | embryonic stage 16,lateral trunk primordium | embryonic stage 16,dorsal branch primordium | embryonic stage 16,dorsal trunk primordium | embryonic stage 16,visceral branch | embryonic stage 16" DRSC14895 E 0.235356986 -1.396830861 -0.305381765 -2.727490111 -0.17969087 -0.094437653 FBgn0052053 CG32053 - http://flybase.org/reports/FBgn0052053 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from electronic annotation with InterPro:IPR005828 "transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005828, InterPro:IPR005829" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005828, InterPro:IPR005829" "CG6645, CG32053" "IPR005829:Sugar transporter, conserved site, IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG32053 27-Aug-18 DroID_v2018_08 "Drer\slc2a13b, Drer\slc2a6, Drer\slc2a8, Drer\LOC101882338, Drer\slc2a10, Drer\slc2a12" "Scer\MAL11, Scer\HXT2, Scer\HXT6, Scer\HXT17, Scer\ITR2, Scer\HXT15, Scer\HXT14, Scer\VBA3, Scer\AZR1, Scer\HXT10, Scer\HXT5, Scer\ENB1, Scer\YDL199C, Scer\HXT13, Scer\SNF3, Scer\HXT4, Scer\GEX1, Scer\HXT7, Scer\YDR387C, Scer\GEX2, Scer\ITR1, Scer\MAL31, Scer\VBA2, Scer\MPH2, Scer\HXT9, Scer\YMR279C, Scer\ATR1, Scer\HXT8, Scer\MPH3, Scer\SGE1, Scer\HXT16, Scer\HXT1, Scer\VBA4, Scer\GAL2, Scer\HXT11, Scer\VBA1, Scer\STL1, Scer\VBA5, Scer\YFL040W, Scer\RGT2, Scer\HXT3" "Cele\hmit-1.2, Cele\fgt-1" "Xtro\slc2a12, Xtro\slc2a10, Xtro\slc2a8, Xtro\slc2a6" "Mmus\Slc2a10, Mmus\Slc2a6, Mmus\Slc2a8, Mmus\Slc2a12, Mmus\Slc2a13" "Hsap\SLC2A12, Hsap\SLC2A6, Hsap\SLC2A10, Hsap\SLC2A8, Hsap\SLC2A13" "partially lethal - majority die,some die during pupal stage" FBgn0259163 CG42268 - http://flybase.org/reports/FBgn0259163 protein_coding_gene - imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype - "CG42268, CG32044, CG6740, CG14170, CG32046" - CG42268 27-Aug-18 DroID_v2018_08 - - - - - - DRSC10171 IE 2.294236057 1.919991562 2.039172495 -1.637676671 0.864804219 1.482798318 FBgn0069915 CG41138 - http://flybase.org/reports/FBgn0069915 protein_coding_gene - - - CG41138 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005572 l(3)85Eh lethal (3) 85Eh http://flybase.org/reports/FBgn0005572 - gene - - - l(3)85Eh - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0033924 CG8613 - http://flybase.org/reports/FBgn0033924 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR008928, InterPro:IPR012341" - - CG8613 "IPR008928:Six-hairpin glycosidase-like, IPR012336:Thioredoxin-like fold, IPR024705:Spermatogenesis-associated protein 20, IPR004879:Domain of unknown function DUF255" CG8613 27-Aug-18 DroID_v2018_08 Drer\spata20 - Cele\B0495.5 Xtro\spata20 Mmus\Spata20 Hsap\SPATA20 FBgn0000154 B Bar http://flybase.org/reports/FBgn0000154 - gene "transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from mutant phenotype" leg disc development ; GO:0035218 | inferred from mutant phenotype chaeta morphogenesis ; GO:0008407 | non-traceable author statement imaginal disc-derived leg segmentation ; GO:0036011 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "Bar, BarH1, bar, BB, B" - - 27-Aug-18 DroID_v2018_08 - - - - - - "wild-type,visible,dominant,recessive,cold sensitive,viable,female fertile,lethal,male fertile,poor,neuroanatomy defective,fertile,male" "eye,wing,cold sensitive,macrochaeta,tarsal segment 4,anterior,tarsal segment 3,pretarsus,ommatidium,morphogenetic furrow,optic lobe,medial ocellus,unguis,femur,tibia,metatarsus" FBgn0024849 nkg nanking http://flybase.org/reports/FBgn0024849 - gene - Nebenkern assembly ; GO:0007287 | inferred from mutant phenotype sperm individualization ; GO:0007291 | inferred from mutant phenotype - "ms(3)3915, nkg" - - 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,recessive,viable" "spermatozoon,primary spermatocyte cyst,spermatid & nucleus,Nebenkern" FBgn0065764 l(2)SH0475 lethal (2) SH0475 http://flybase.org/reports/FBgn0065764 gene - - - "l(2)SH0475, l(2)SH2 0475" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0033048 CG7881 - http://flybase.org/reports/FBgn0033048 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 anion transport ; GO:0006820 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000910672 CG7881 "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG7881 27-Aug-18 DroID_v2018_08 "Drer\slc17a7a, Drer\ppt1, Drer\si:ch1073-513e17.1, Drer\slc17a5, Drer\slc17a8, Drer\slc17a6b, Drer\slc17a6a" "Scer\YCT1, Scer\YIL166C, Scer\TNA1, Scer\FEN2, Scer\DAL5, Scer\VHT1, Scer\THI73, Scer\SEO1" "Cele\T22F3.7, Cele\M162.5, Cele\F56A4.10, Cele\slc-17.4, Cele\T19D12.9, Cele\T19D12.10, Cele\slc-17.2, Cele\F59A1.13, Cele\C01B4.7, Cele\vglu-2, Cele\C18H9.5, Cele\Y4C6B.3, Cele\W04C9.6, Cele\C01B4.8, Cele\T02B11.6, Cele\T22F3.10, Cele\slc-17.8, Cele\Y19D10A.8, Cele\eat-4, Cele\vglu-3, Cele\slc-17.3, Cele\Y51B9A.6, Cele\C39E9.7, Cele\K11G9.5, Cele\K08C7.1, Cele\F41C3.2, Cele\F10C2.7, Cele\T22F3.8, Cele\Y19D10A.11, Cele\T28H11.8, Cele\cima-1, Cele\Y4C6B.4, Cele\F56A4.12, Cele\D1046.4, Cele\Y19D10A.4, Cele\T22F3.11, Cele\Y15E3A.4, Cele\R10D12.1, Cele\F44E7.7, Cele\C35A5.3, Cele\C18D1.2, Cele\F11A5.9, Cele\slc-17.1, Cele\T27D12.1, Cele\Y19D10A.5, Cele\slc-17.5, Cele\M117.1, Cele\H11E01.2, Cele\T01H3.3, Cele\slc-17.9" - "Mmus\Slc17a5, Mmus\Slc17a2, Mmus\Slc17a7, Mmus\Slc17a1, Mmus\Slc17a6, Mmus\Slc17a8, Mmus\Slc17a3, Mmus\Slc17a4" "Hsap\SLC17A1, Hsap\SLC17A3, Hsap\SLC17A2, Hsap\SLC17A4, Hsap\SLC17A7, Hsap\SLC17A6, Hsap\SLC17A8, Hsap\SLC17A5" "body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0051171 CG31171 - http://flybase.org/reports/FBgn0051171 protein_coding_gene - - - CG31171 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033931 Obp50e Odorant-binding protein 50e http://flybase.org/reports/FBgn0033931 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush extracellular region ; GO:0005576 | inferred from sequence model "CG13939, Obp50e, DmelObp50e" IPR006170:Pheromone/general odorant binding protein CG13939 27-Aug-18 DroID_v2018_08 - - - - - - DRSC06434 E 0.012252043 0.51141493 0.09562802 1.659874165 -0.917623538 0.457580055 FBgn0267164 asRNA:CR45604 - http://flybase.org/reports/FBgn0267164 non_protein_coding_gene - - - CR45604 - CR45604 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265263 CG42688 - http://flybase.org/reports/FBgn0265263 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42688, DMG8-chr2L.34.001, anon-SAGE:Wang-006" - CG42688 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0013651 ms(2)ry7 ms(2)ry7 http://flybase.org/reports/FBgn0013651 - gene - - - "ms(2)7, ms(2)ry7" - - 27-Aug-18 DroID_v2018_08 - - - - - - male sterile FBgn0085346 CG34317 - http://flybase.org/reports/FBgn0085346 protein_coding_gene ribonuclease activity ; GO:0004540 | inferred from electronic annotation with InterPro:IPR002759 tRNA processing ; GO:0008033 | inferred from electronic annotation with InterPro:IPR002759 cellular_component ; GO:0005575 | no biological data available "CG34317, Dromel_CG7950_FBtr0085563_CHCHD4inmorf_uORF" IPR002759:Ribonuclease P/MRP protein subunit CG34317 27-Aug-18 DroID_v2018_08 "Drer\chchd4b, Drer\chchd4a, Drer\rpp14" - - "Xtro\rpp14, Xtro\chchd4" "Mmus\Chchd4, Mmus\Rpp14" "Hsap\RPP14, Hsap\CHCHD4" FBgn0050291 CG30291 - http://flybase.org/reports/FBgn0050291 protein_coding_gene molecular_function ; GO:0003674 | no biological data available regulation of cyclin-dependent protein serine/threonine kinase activity ; GO:0000079 | inferred from sequence or structural similarity with UniProtKB:Q9JLH7 endomembrane system ; GO:0012505 | inferred from direct assay "CG3282, CG30291" IPR008491:Protein of unknown function DUF773 CG30291 27-Aug-18 DroID_v2018_08 Drer\cdk5rap3 - Cele\cdkr-3 Xtro\cdk5rap3 Mmus\Cdk5rap3 Hsap\CDK5RAP3 viable FBgn0002010 l(2)36Fc lethal (2) 36Fc http://flybase.org/reports/FBgn0002010 - gene - - - "36Fc, Fc, l(2)E53, l(2)36Fc" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0041158 dos::tor dos::tor http://flybase.org/reports/FBgn0041158 engineered_fusion_gene - - - dos::tor - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0012300 Dfd::Ubx Dfd::Ubx http://flybase.org/reports/FBgn0012300 - engineered_fusion_gene - - - Dfd::Ubx - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage" head FBgn0023432 l(2)55Ca lethal (2) 55Ca http://flybase.org/reports/FBgn0023432 - gene - - - l(2)55Ca - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0046689 Takl1 Tak1-like 1 http://flybase.org/reports/FBgn0046689 protein_coding_gene "MAP kinase kinase kinase activity ; GO:0004709 | inferred from electronic annotation with InterPro:IPR017421 magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR017421 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 protein kinase activity ; GO:0004672 | inferred from sequence or structural similarity with HGNC:6859 protein kinase activity ; GO:0004672 | inferred from biological aspect of ancestor with PANTHER:PTN000584058 signal transducer activity ; GO:0004871 | inferred from biological aspect of ancestor with PANTHER:PTN000584058" protein phosphorylation ; GO:0006468 | inferred from biological aspect of ancestor with PANTHER:PTN000584058 intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN000584058 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with Tak1 intracellular ; GO:0005622 | inferred from biological aspect of ancestor with PANTHER:PTN000584058 "TAKL1, anon-AE003732.1, CG31421, Takl1, FBgn0046689, takl1" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR017421:Mitogen-activated protein (MAP) kinase kinase kinase 7, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain" CG31421 27-Aug-18 DroID_v2018_08 "Drer\map3k9, Drer\pbk, Drer\map3k10, Drer\zgc:66101, Drer\lrrk2, Drer\ripk4, Drer\ripk3, Drer\chek2, Drer\map4k6, Drer\ripk2, Drer\LOC405768, Drer\sik1, Drer\mast1b, Drer\stk36, Drer\mark1, Drer\zak, Drer\plk3, Drer\map3k7, Drer\mark3b, Drer\dstyk, Drer\mos, Drer\ripk1l, Drer\si:ch211-120p12.3" "Scer\SKS1, Scer\SNF1" "Cele\spe-8, Cele\sad-1, Cele\mom-4, Cele\Y105C5A.24" "Xtro\lrrk2, Xtro\ankk1, Xtro\pbk, Xtro\sik2, Xtro\zak, Xtro\dstyk, Xtro\ripk1, Xtro\mlkl, Xtro\map3k7, Xtro\mapk15, Xtro\brsk1, Xtro\LOC100490493, Xtro\map3k10, Xtro\lrrk1, Xtro\ripk4, Xtro\map3k9, Xtro\hunk" "Mmus\Zak, Mmus\Mark2, Mmus\Smok2b, Mmus\Gm7358, Mmus\Gm4922, Mmus\Smok3b, Mmus\Mark3, Mmus\Prkch, Mmus\Gm14147, Mmus\Pbk, Mmus\Mlkl, Mmus\BC021891, Mmus\Ripk2, Mmus\Dstyk, Mmus\Mos, Mmus\Ripk3, Mmus\Sik3, Mmus\Sik2, Mmus\Smok2a, Mmus\Snrk, Mmus\Lrrk1, Mmus\Ripk4, Mmus\Ripk1, Mmus\4921509C19Rik, Mmus\Map3k9, Mmus\Map3k11, Mmus\Map3k7, Mmus\Map3k10, Mmus\Lrrk2" "Hsap\RIPK2, Hsap\DSTYK, Hsap\MAP3K9, Hsap\LRRK2, Hsap\RIPK1, Hsap\MLKL, Hsap\SNRK, Hsap\BRSK1, Hsap\MAP3K7, Hsap\LRRK1, Hsap\PBK, Hsap\MARK2, Hsap\MAP3K10, Hsap\MARK3, Hsap\RIPK4, Hsap\MOS, Hsap\MAP3K20, Hsap\MAP3K21, Hsap\MAP3K11, Hsap\SIK2, Hsap\RIPK3" viable FBgn0003421 sld slender http://flybase.org/reports/FBgn0003421 - gene - - - sld - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,female,poor,male,reduced,visible,male fertile,male sterile" "adult abdomen,eye,wing" FBgn0020317 anon-8F6 anon-8F6 http://flybase.org/reports/FBgn0020317 - gene - - - "8F6, anon-8F6" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0041336 Cyp6t2Psi Cyp6t2Psi http://flybase.org/reports/FBgn0041336 pseudogene_attribute - - - "6t2p, Cyp6t2p, CR31621, Cyp6t2Psi" - CR31621 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065576 l(2)SH0953 lethal (2) SH0953 http://flybase.org/reports/FBgn0065576 gene - - - "l(2)SH0953, l(2)SH2 0953" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0263496 lncRNA:CR43485 - http://flybase.org/reports/FBgn0263496 non_protein_coding_gene - - - CR43485 - CR43485 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036319 Ent3 Equilibrative nucleoside transporter 3 http://flybase.org/reports/FBgn0036319 protein_coding_gene monoamine transmembrane transporter activity ; GO:0008504 | inferred from electronic annotation with InterPro:IPR030198 nucleoside transmembrane transporter activity ; GO:0005337 | inferred from sequence or structural similarity with HGNC:11003 inferred from sequence or structural similarity with HGNC:11004 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR030198 nucleoside transport ; GO:0015858 | inferred from sequence or structural similarity with HGNC:11003 inferred from sequence or structural similarity with HGNC:11004 "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002259, InterPro:IPR030198 integral component of membrane ; GO:0016021 | inferred from sequence model" "DmENT3, CG11010, Ent3, ent3, DmEnt3" "IPR020846:Major facilitator superfamily domain, IPR030198:Equilibrative nucleoside transporter 4, IPR002259:Equilibrative nucleoside transporter" CG11010 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-160d14.6, Drer\slc29a3, Drer\slc29a1a, Drer\slc29a4, Drer\slc29a1b, Drer\slc29a2, Drer\LOC100334018" Scer\FUN26 - Xtro\slc29a2 "Mmus\Slc29a4, Mmus\Slc29a1, Mmus\Slc29a2, Mmus\Slc29a3" "Hsap\SLC29A4, Hsap\SLC29A2, Hsap\SLC29A1, Hsap\SLC29A3" viable FBgn0263124 Ubx::Csal\Ubx2 - http://flybase.org/reports/FBgn0263124 engineered_fusion_gene - - - "Ubx::Zzzz\Ubx2, Ubx::Csal\Ubx2" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0084045 CG41485 - http://flybase.org/reports/FBgn0084045 protein_coding_gene - - - CG41485 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005167 l(2)G562 lethal (2) G562 http://flybase.org/reports/FBgn0005167 - gene - - - l(2)G562 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0039636 Atg14 Autophagy-related 14 http://flybase.org/reports/FBgn0039636 protein_coding_gene molecular_function ; GO:0003674 | no biological data available positive regulation of autophagy ; GO:0010508 | inferred from electronic annotation with InterPro:IPR018791 regulation of autophagy ; GO:0010506 | inferred from mutant phenotype autophagy ; GO:0006914 | inferred from mutant phenotype "phosphatidylinositol 3-kinase complex, class III, type I ; GO:0034271 | inferred from sequence or structural similarity with SGD:S000000332" "Atg14, CG11877" IPR018791:UV radiation resistance protein/autophagy-related protein 14 CG11877 27-Aug-18 DroID_v2018_08 "Drer\tbpl2, Drer\zgc:113944" - Cele\epg-8 Xtro\atg14 Mmus\Atg14 Hsap\ATG14 "viable,fertile" "embryonic/larval fat body,somatic clone | third instar larval stage" FBgn0033412 CG13955 - http://flybase.org/reports/FBgn0033412 protein_coding_gene - - - CG13955 - CG13955 27-Aug-18 DroID_v2018_08 Drer\tchp - - - Mmus\Mad1l1 - viable FBgn0263018 snRNA:U4atac small nuclear RNA U4atac at 82E http://flybase.org/reports/FBgn0263018 snRNA_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity" U4atac snRNP ; GO:0005690 | inferred from sequence or structural similarity "CR43269, U4atac, U4atac-82E, CR32860, snRNA:U4atac:82E, U4atac:cno-a, snRNA_01, chr3R:1020715..1020926" - CR43269 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065379 l(2)SH1671 lethal (2) SH1671 http://flybase.org/reports/FBgn0065379 gene - - - "l(2)SH1671, l(2)SH2 1671" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0040396 CG3939 - http://flybase.org/reports/FBgn0040396 protein_coding_gene protein-disulfide reductase activity ; GO:0047134 | inferred from biological aspect of ancestor with PANTHER:PTN000278790 - cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000278790 "EG:140G11.5, BEST:SD07039, CG3939" "IPR010357:Protein of unknown function DUF953, thioredoxin-like, IPR012336:Thioredoxin-like fold" CG3939 27-Aug-18 DroID_v2018_08 Drer\txndc17 - Cele\Y71H2AR.1 - Mmus\Txndc17 Hsap\TXNDC17 viable FBgn0034400 CG15099 - http://flybase.org/reports/FBgn0034400 protein_coding_gene - Golgi to endosome transport ; GO:0006895 | inferred from biological aspect of ancestor with PANTHER:PTN000361806 trans-Golgi network ; GO:0005802 | inferred from biological aspect of ancestor with PANTHER:PTN000361806 endosome ; GO:0005768 | inferred from biological aspect of ancestor with PANTHER:PTN000361806 CG15099 "IPR007249:Dopey, N-terminal" CG15099 27-Aug-18 DroID_v2018_08 "Drer\dopey1, Drer\dopey2" Scer\DOP1 Cele\pad-1 Xtro\dopey2 "Mmus\Dopey2, Mmus\Dopey1" "Hsap\DOPEY2, Hsap\DOPEY1" viable DRSC06528 K 0.637701493 0.163588789 1.422511617 0.004959979 -2.167634915 -0.421374931 FBgn0265912 lncRNA:CR44701 - http://flybase.org/reports/FBgn0265912 non_protein_coding_gene - - - "lincRNA.97, CR44701" - CR44701 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065711 l(2)SH0591 lethal (2) SH0591 http://flybase.org/reports/FBgn0065711 gene - - - "l(2)SH0591, l(2)SH2 0591" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0085751 CR40582 - http://flybase.org/reports/FBgn0085751 rRNA_gene - - - CR40582 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0058389 CG40389 - http://flybase.org/reports/FBgn0058389 protein_coding_gene - - - CG40389 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267921 lncRNA:CR46202 - http://flybase.org/reports/FBgn0267921 non_protein_coding_gene - - - "CR46202, lincRNA.227" - CR46202 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0045759 bin biniou http://flybase.org/reports/FBgn0045759 protein_coding_gene "transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from genetic interaction with dpp sequence-specific DNA binding ; GO:0043565 | inferred from direct assay transcription regulatory region sequence-specific DNA binding ; GO:0000976 | inferred from direct assay transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from genetic interaction with Hand transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from genetic interaction with βTub60D" regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from mutant phenotype mesodermal cell fate commitment ; GO:0001710 | inferred from mutant phenotype salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "Bin, Dmbin, FoxF, CG18647, XIV, l(3)65CEe, bin, FOXF, DmFoxF, binI, BIN" "IPR001766:Fork head domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR030456:Fork head domain conserved site 2" CG18647 27-Aug-18 DroID_v2018_08 "Drer\foxf1, Drer\foxf2b, Drer\foxq2, Drer\foxa3, Drer\foxf2a, Drer\foxq1a, Drer\foxp4, Drer\foxh1, Drer\foxi3b" "Scer\HCM1, Scer\FKH2, Scer\FHL1, Scer\FKH1" "Cele\fkh-9, Cele\let-381" "Xtro\foxq1, Xtro\foxf2, Xtro\foxd3, Xtro\foxh1, Xtro\foxp4, Xtro\foxf1, Xtro\foxd4l1.1" "Mmus\Foxp4, Mmus\Foxf2, Mmus\Foxi2, Mmus\Foxk1, Mmus\Foxk2, Mmus\Foxf1, Mmus\Foxh1, Mmus\Foxq1, Mmus\Foxs1" "Hsap\FOXN1, Hsap\FOXF1, Hsap\FOXQ1, Hsap\FOXC2, Hsap\FOXD4L1, Hsap\FOXD4L3, Hsap\FOXI2, Hsap\FOXK1, Hsap\FOXP4, Hsap\FOXH1, Hsap\FOXF2" "lethal,cell migration defective,viable" "anterior embryonic/larval midgut,presumptive embryonic salivary gland,circular visceral muscle primordium,midgut constriction,longitudinal visceral muscle primordium,visceral mesoderm derivative,embryonic somatic muscle,embryonic pericardial cell" FBgn0267925 lncRNA:CR46206 - http://flybase.org/reports/FBgn0267925 non_protein_coding_gene - - - "CR46206, lincRNA.123" - CR46206 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0023112 anon-10Av anon-10Av http://flybase.org/reports/FBgn0023112 - gene - - - "15, anon-10Av" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034565 CG15650 - http://flybase.org/reports/FBgn0034565 protein_coding_gene - - - CG15650 - CG15650 27-Aug-18 DroID_v2018_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0023409 Ars-region46 Autonomous replicating sequence region 46 http://flybase.org/reports/FBgn0023409 - region - - - "dARS46, Ars-region46, Ars46" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0029942 CG2059 - http://flybase.org/reports/FBgn0029942 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from direct assay biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG2059 "IPR000073:Alpha/beta hydrolase fold-1, IPR029058:Alpha/Beta hydrolase fold" CG2059 27-Aug-18 DroID_v2018_08 "Drer\abhd11, Drer\abhd8b" "Scer\LPX1, Scer\YGR015C, Scer\IMO32" "Cele\abhd-11.1, Cele\abhd-11.2" "Xtro\abhd8, Xtro\abhd11" "Mmus\Abhd8, Mmus\Abhd11" Hsap\ABHD11 FBgn0243514 eater eater http://flybase.org/reports/FBgn0243514 protein_coding_gene scavenger receptor activity ; GO:0005044 | inferred from direct assay peptidoglycan binding ; GO:0042834 | inferred from direct assay "immune response ; GO:0006955 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype defense response to bacterium ; GO:0042742 | inferred from mutant phenotype positive regulation of phagocytosis ; GO:0050766 | inferred from mutant phenotype phagocytosis, recognition ; GO:0006910 | inferred from mutant phenotype defense response to Gram-positive bacterium ; GO:0050830 | inferred from mutant phenotype positive regulation of cell-substrate adhesion ; GO:0010811 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype" cell surface ; GO:0009986 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model "eater, Eater, CG6124, CT19227, C901-like, Dmel_CG6124" "IPR000742:EGF-like domain, IPR003341:Cysteine rich repeat, tripleX" CG6124 27-Aug-18 DroID_v2018_08 "Drer\wu:fj11g02, Drer\si:ch1073-110a20.2, Drer\angpt4, Drer\angptl1a, Drer\megf6a, Drer\angptl2b, Drer\si:ch1073-110a20.3, Drer\megf10, Drer\angpt1, Drer\figf, Drer\zgc:171687, Drer\dkk2, Drer\fibcd1, Drer\fgb, Drer\ltbp3, Drer\scube3, Drer\tnr, Drer\esm1, Drer\si:ch1073-110a20.1, Drer\si:ch211-157b11.8, Drer\tnfaip6, Drer\tnc, Drer\LOC100007488, Drer\ccbe1, Drer\si:ch211-203k16.3, Drer\si:zfos-2330d3.3, Drer\angptl6, Drer\fgl2a, Drer\angpt2b, Drer\megf6b, Drer\scube1, Drer\megf11, Drer\scarf1, Drer\vegfc, Drer\fgg, Drer\zgc:158328, Drer\angptl3, Drer\pear1, Drer\tnw, Drer\fga, Drer\tnxba, Drer\fgl2b, Drer\angptl5, Drer\angptl4, Drer\scube2, Drer\zgc:194887, Drer\zmp:0000000846, Drer\angptl2a, Drer\vegfab, Drer\si:zfos-2330d3.8, Drer\si:zfos-2330d3.6, Drer\si:zfos-2330d3.1, Drer\dkk1a, Drer\si:ch211-287a12.9" - "Cele\Y26D4A.12, Cele\pqn-13, Cele\K10D3.4, Cele\B0393.5, Cele\arg-1, Cele\ZK1193.3, Cele\M195.2, Cele\ZC504.1, Cele\Y69H2.3, Cele\W05B2.2, Cele\Y34B4A.5, Cele\Y43C5A.2, Cele\F07H5.8, Cele\abu-4, Cele\abu-10, Cele\Y69H2.10, Cele\T15B7.1, Cele\ensh-1, Cele\R09H10.5, Cele\C08G9.2, Cele\F35A5.4" "Xtro\fibcd1, Xtro\LOC100488177, Xtro\stab2, Xtro\fgl2, Xtro\tnr, Xtro\tnfaip6, Xtro\angptl3, Xtro\angptl4, Xtro\fcn3, Xtro\fcn1, Xtro\fgg, Xtro\mfap4, Xtro\fgl1, Xtro\fga, Xtro\angptl2, Xtro\fgb, Xtro\megf11, Xtro\scube1, Xtro\LOC100497330, Xtro\fcn2, Xtro\tnn, Xtro\tnc, Xtro\LOC100491105, Xtro\angpt4, Xtro\angpt1, Xtro\tnxb, Xtro\angptl5" "Mmus\Megf11, Mmus\Fgg, Mmus\Fgl2, Mmus\Fgl1, Mmus\Angptl7, Mmus\Fcnb, Mmus\Angptl6, Mmus\Tnn, Mmus\Scube3, Mmus\Esm1, Mmus\Tnr, Mmus\Egfem1, Mmus\Pear1, Mmus\Angptl3, Mmus\Dkk2, Mmus\Scube1, Mmus\Angptl1, Mmus\Fibcd1, Mmus\Stab1, Mmus\Megf6, Mmus\Angptl2, Mmus\Vegfd, Mmus\Tnxb, Mmus\Scube2, Mmus\Fgb, Mmus\Megf10, Mmus\Scarf1, Mmus\Tnc, Mmus\Angpt1, Mmus\Fga, Mmus\Angpt2, Mmus\Fcna, Mmus\Mfap4, Mmus\Angptl4, Mmus\Vegfc, Mmus\Dkk3, Mmus\Tnfaip6, Mmus\Angpt4" "Hsap\MEGF11, Hsap\FIBCD1, Hsap\VEGFD, Hsap\FGB, Hsap\DKK2, Hsap\FCN2, Hsap\ANGPTL7, Hsap\SCARF1, Hsap\SCUBE3, Hsap\TNXB, Hsap\FGG, Hsap\SCARF2, Hsap\TNC, Hsap\ANGPTL3, Hsap\TNN, Hsap\FCN3, Hsap\ANGPT4, Hsap\FGA, Hsap\SCUBE2, Hsap\ANGPT1, Hsap\FGL2, Hsap\ANGPT2, Hsap\VEGFC, Hsap\SCUBE1, Hsap\ANGPTL1, Hsap\ANGPTL6, Hsap\TNR, Hsap\ANGPTL2, Hsap\MEGF6, Hsap\PEAR1, Hsap\MEGF10, Hsap\TNFAIP6, Hsap\ANGPTL4, Hsap\FGL1, Hsap\ANGPTL5" FBgn0011620 l(1)K49c28-A3 lethal (1) K49c28-A3 http://flybase.org/reports/FBgn0011620 - gene - - - l(1)K49c28-A3 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0259409 EP-160 - http://flybase.org/reports/FBgn0259409 gene - - - EP-160 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing vein,wing,chaeta" FBgn0262373 mir-9a mir-9a stem loop http://flybase.org/reports/FBgn0262373 miRNA_gene - sensory organ boundary specification ; GO:0008052 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype gene silencing by miRNA ; GO:0035195 | inferred from direct assay wing disc development ; GO:0035220 | inferred from genetic interaction with Bx inferred from mutant phenotype regulation of multicellular organism growth ; GO:0040014 | inferred from mutant phenotype regulation of insulin receptor signaling pathway ; GO:0046626 | inferred from mutant phenotype - "miR-9a, mir-9a, MIR-9, CR42891, miR-9, mir-9, CR33063, mir-9A, transfrag 22, dme-miR-9a, miR9a, dme-mir-9a, dme-miR-9a-5p" - CR42891 27-Aug-18 DroID_v2018_08 - - - - - - embryonic stage -- adult stage FBgn0000218 brh brown head http://flybase.org/reports/FBgn0000218 - gene - - - brh - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "embryonic head,denticle belt" FBgn0018737 Dns Dense http://flybase.org/reports/FBgn0018737 - gene - - - Dns - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,dominant,viable" macrochaeta FBgn0031296 CG4415 - http://flybase.org/reports/FBgn0031296 protein_coding_gene - - - CG4415 "IPR002715:Nascent polypeptide-associated complex NAC domain, IPR016641:Nascent polypeptide-associated complex subunit alpha" CG4415 27-Aug-18 DroID_v2018_08 "Drer\naca, Drer\nacad" Scer\EGD2 Cele\icd-2 "Xtro\naca.2, Xtro\naca" "Mmus\Nacad, Mmus\Naca" "Hsap\NACAD, Hsap\NACA2, Hsap\NACA" "female fertile,viable" FBgn0040025 CG12577 - http://flybase.org/reports/FBgn0040025 protein_coding_gene - - - CG12577 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031676 senju senju http://flybase.org/reports/FBgn0031676 protein_coding_gene sugar:proton symporter activity ; GO:0005351 | inferred from electronic annotation with InterPro:IPR007271 UDP-galactose transmembrane transporter activity ; GO:0005459 | inferred from direct assay carbohydrate transport ; GO:0008643 | inferred from electronic annotation with InterPro:IPR007271 UDP-galactose transport ; GO:0015785 | inferred from direct assay negative regulation of Toll signaling pathway ; GO:0045751 | inferred from mutant phenotype negative regulation of innate immune response ; GO:0045824 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR007271 Golgi membrane ; GO:0000139 | inferred from electronic annotation with InterPro:IPR007271 Golgi apparatus ; GO:0005794 | inferred from direct assay Golgi medial cisterna ; GO:0005797 | inferred from direct assay "senju, CG14040" IPR007271:Nucleotide-sugar transporter CG14040 27-Aug-18 DroID_v2018_08 "Drer\slc35a2, Drer\slc35a3a, Drer\slc35a5, Drer\slc35a1, Drer\slc35a3b, Drer\slc35a4" - Cele\nstp-5 "Xtro\slc35a5, Xtro\slc35a1, Xtro\slc35a3.2, Xtro\slc35a3.1" "Mmus\Slc35a1, Mmus\Slc35a3, Mmus\Slc35a5, Mmus\Slc35a4, Mmus\Slc35a2" "Hsap\SLC35A4, Hsap\SLC35A2, Hsap\SLC35A1, Hsap\SLC35A3, Hsap\SLC35A5" viable FBgn0011175 l(1)291-53 lethal (1) 291-53 http://flybase.org/reports/FBgn0011175 FBgn0010199 gene - - - "291-53, l(1)291-53" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,male sterile,visible" wing FBgn0004472 apo altered pattern orientation http://flybase.org/reports/FBgn0004472 - gene - - - "apo[S129], apo" - - 27-Aug-18 DroID_v2018_08 - - - - - - "visual behavior defective,recessive" FBgn0024565 l(3)L6710 lethal (3) L6710 http://flybase.org/reports/FBgn0024565 - gene - - - l(3)L6710 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0011791 l(3)j4E6 lethal (3) j4E6 http://flybase.org/reports/FBgn0011791 - gene - - - l(3)j4E6 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0028942 CG16852 - http://flybase.org/reports/FBgn0028942 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - "BG:BACR48E02.2, BcDNA:AT28681, CG16852" - CG16852 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0034251 ND-51L1 NADH dehydrogenase (ubiquinone) 51 kDa subunit-like 1 http://flybase.org/reports/FBgn0034251 protein_coding_gene "NADH dehydrogenase (ubiquinone) activity ; GO:0008137 | inferred from electronic annotation with InterPro:IPR001949 NAD binding ; GO:0051287 | inferred from electronic annotation with InterPro:IPR011537 4 iron, 4 sulfur cluster binding ; GO:0051539 | inferred from electronic annotation with InterPro:IPR001949, InterPro:IPR011537, InterPro:IPR019575 FMN binding ; GO:0010181 | inferred from electronic annotation with InterPro:IPR001949, InterPro:IPR011537" "mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with WB:WBGene00003831" - "CG11423, NUBM, ND-51L1" "IPR001949:NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site, IPR011537:NADH ubiquinone oxidoreductase, F subunit, IPR011538:NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain, IPR019575:NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain" CG11423 27-Aug-18 DroID_v2018_08 Drer\ndufv1 - Cele\nuo-1 Xtro\ndufv1 Mmus\Ndufv1 Hsap\NDUFV1 viable FBgn0065599 l(2)SH0875 lethal (2) SH0875 http://flybase.org/reports/FBgn0065599 gene - - - l(2)SH0875 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0052640 CG32640 - http://flybase.org/reports/FBgn0052640 protein_coding_gene - - - CG32640 "IPR001623:DnaJ domain, IPR018253:DnaJ domain, conserved site" CG32640 27-Aug-18 DroID_v2018_08 - Scer\HLJ1 Cele\dnj-26 - - - "viable,fertile" FBgn0004855 RpII15 RNA polymerase II 15kD subunit http://flybase.org/reports/FBgn0004855 - protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001222, InterPro:IPR012164 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001222 DNA-directed RNA polymerase activity ; GO:0003899 | inferred from sequence or structural similarity with HGNC:9196 inferred from sequence or structural similarity with SGD:S000003038" mRNA cleavage ; GO:0006379 | inferred from electronic annotation with InterPro:IPR034012 transcription from RNA polymerase II promoter ; GO:0006366 | inferred from sequence or structural similarity with HGNC:9196 inferred from sequence or structural similarity with SGD:S000003038 mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs "DNA-directed RNA polymerase II, core complex ; GO:0005665 | inferred from sequence or structural similarity with HGNC:9196 inferred from sequence or structural similarity with SGD:S000003038 nucleus ; GO:0005634 | inferred from direct assay DNA-directed RNA polymerase II, core complex ; GO:0005665 | inferred from direct assay" "pol II, Pol II, RNAP, PolII, RNApolII, RNAP II, H5, polII, dRPB9, RNA Pol II, RNA pol II, CG3284, RNA polII, RPII15, RpII215, l(3)Z23, l(3)88Be, RpII15, Rpb9" "IPR001222:Zinc finger, TFIIS-type, IPR001529:DNA-directed RNA polymerase, M/15kDa subunit, IPR019761:DNA-directed RNA polymerase M, 15kDa subunit, conserved site, IPR012164:DNA-directed RNA polymerase subunit/transcription factor S, IPR034012:Pol II subunit B9, C-terminal zinc ribbon" CG3284 27-Aug-18 DroID_v2018_08 Drer\polr2i Scer\RPB9 Cele\rpb-9 Xtro\polr2i Mmus\Polr2i Hsap\POLR2I " embryonic stage -- adult stage , adult stage , embryonic stage , larval stage "

ubiquitous "lethal,polyphasic,recessive,wild-type,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "capitellum,ganglion mother cell" DRSC16832 K -1.030864731 1.445908083 -0.478544839 -0.418832344 1.972142923 3.033536975 FBgn0002147 l(2)K513 lethal (2) K513 http://flybase.org/reports/FBgn0002147 - gene - - - l(2)K513 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0260933 rempA reduced mechanoreceptor potential A http://flybase.org/reports/FBgn0260933 protein_coding_gene molecular_function ; GO:0003674 | no biological data available sensory perception of sound ; GO:0007605 | inferred from mutant phenotype cilium assembly ; GO:0060271 | inferred from expression pattern non-motile cilium assembly ; GO:1905515 | inferred from sequence or structural similarity with Oseg1 intraciliary retrograde transport ; GO:0035721 | inferred from mutant phenotype non-motile cilium assembly ; GO:1905515 | inferred from mutant phenotype non-motile cilium ; GO:0097730 | inferred from direct assay axoneme ; GO:0005930 | inferred from biological aspect of ancestor with PANTHER:PTN000404360 intraciliary transport particle A ; GO:0030991 | inferred from biological aspect of ancestor with PANTHER:PTN000404361 ciliary basal body ; GO:0036064 | inferred from biological aspect of ancestor with PANTHER:PTN000404360 "Oseg3, RempA, IFT140, rempA, IFT40, CG11838, oseg3, remp, OSEG3, CHE-11, OSEG, Che-11, REMPA" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain, IPR011990:Tetratricopeptide-like helical domain" CG11838 27-Aug-18 DroID_v2018_08 Drer\ift140 - Cele\che-11 Xtro\ift140 Mmus\Ift140 Hsap\IFT140 FBgn0003587 Su(var)2-4 Suppressor of variegation 2-4 http://flybase.org/reports/FBgn0003587 - gene - - - "Su-var(2)4, Su(var)b[5401], Su(var)b5401, Su(var)2-4" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,suppressor of variegation,dominant" FBgn0002667 mat(2)ea-D maternal effect early arrest D http://flybase.org/reports/FBgn0002667 - gene - - - "mat(2)earlyQD68, mat(2)ea-D" - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage" FBgn0034397 CG15082 - http://flybase.org/reports/FBgn0034397 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15082 - CG15082 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0038376 Hmt-1 Heavy metal tolerance factor 1 http://flybase.org/reports/FBgn0038376 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR011527, InterPro:IPR017871 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from sequence or structural similarity with UniProtKB:Q9NP58 heme transporter activity ; GO:0015232 | inferred from sequence or structural similarity with UniProtKB:Q9NP58 cadmium ion transmembrane transporter activity ; GO:0015086 | NOT inferred from genetic interaction with PomBase:SPCC737.09c" cadmium ion transmembrane transport ; GO:0070574 | NOT inferred from genetic interaction with PomBase:SPCC737.09c heme transport ; GO:0015886 | inferred from sequence or structural similarity with UniProtKB:Q9NP58 response to cadmium ion ; GO:0046686 | inferred from genetic interaction with PomBase:SPCC737.09c integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011527 vacuolar membrane ; GO:0005774 | inferred from direct assay mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with UniProtKB:Q9NP58 "EP(3)3387, Hmt-1, hmt-1, CG4225" "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR011527:ABC transporter type 1, transmembrane domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR017871:ABC transporter, conserved site, IPR032410:Mitochondrial ABC-transporter, N-terminal five TM domain" CG4225 27-Aug-18 DroID_v2018_08 "Drer\abcb6a, Drer\abcb7, Drer\abcb6b" Scer\ATM1 "Cele\hmt-1, Cele\abtm-1" "Xtro\abcb7, Xtro\abcb6" "Mmus\Abcb6, Mmus\Abcb7" "Hsap\ABCB7, Hsap\ABCB6" "viable,fertile" FBgn0016697 Prosalpha5 Proteasome alpha5 subunit http://flybase.org/reports/FBgn0016697 - protein_coding_gene "threonine-type endopeptidase activity ; GO:0004298 | inferred from electronic annotation with InterPro:IPR001353, InterPro:IPR023332 endopeptidase activity ; GO:0004175 | contributes_to inferred by curator from GO:0005839" proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred by curator from GO:0005839 "proteasome core complex, alpha-subunit complex ; GO:0019773 | inferred from electronic annotation with InterPro:IPR000426 proteasome complex ; GO:0000502 | inferred from direct assay proteasome core complex ; GO:0005839 | inferred from direct assay" "154644_at, prosMA5, PSMA5, PRCZ, alpha5_dm, CG10938, ProsMA5, Prosalpha5, PSA5_DROME, Alpha-5, alpha5, alpha-5" "IPR000426:Proteasome alpha-subunit, N-terminal domain, IPR001353:Proteasome, subunit alpha/beta, IPR023332:Proteasome alpha-type subunit, IPR033812:Proteasome subunit alpha5, IPR029055:Nucleophile aminohydrolases, N-terminal" CG10938 27-Aug-18 DroID_v2018_08 "Drer\psma8, Drer\psma2, Drer\psma5" Scer\PUP2 Cele\pas-5 "Xtro\psma5, Xtro\psma2, Xtro\psma7" "Mmus\Psma5, Mmus\Psma2, Mmus\Psma7, Mmus\Psma8" "Hsap\PSMA8, Hsap\PSMA5, Hsap\PSMA2, Hsap\PSMA7" lethal DRSC07514 IEK -2.13486607 -3.202508628 -0.045359637 -1.782343105 1.965226568 1.665925402 FBgn0010056 JmE Ju myoE http://flybase.org/reports/FBgn0010056 - gene - - - "Jm E, JmE" - - 27-Aug-18 DroID_v2018_08 - - - - - - aging defective FBgn0042097 yeti-MBT yeti Malignant Brain Tumor http://flybase.org/reports/FBgn0042097 gene - mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs - "SWC5, yeti-MBT, yeti" - - 27-Aug-18 DroID_v2018_08 - - - - - - polytene chromosome FBgn0004823 fs(2)ltoAPV63 female sterile (2) ltoAPV63 http://flybase.org/reports/FBgn0004823 - gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(2)ltoAPV63 - - 27-Aug-18 DroID_v2018_08 - - - - - - female sterile FBgn0000238 buo burnt orange http://flybase.org/reports/FBgn0000238 - gene - - - buo - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive,eye color defective" pigment cell FBgn0266152 lncRNA:CR44858 - http://flybase.org/reports/FBgn0266152 non_protein_coding_gene - - - CR44858 - CR44858 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267088 lncRNA:CR45532 - http://flybase.org/reports/FBgn0267088 non_protein_coding_gene - - - CR45532 - CR45532 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0003373 Sgs3 Salivary gland secretion 3 http://flybase.org/reports/FBgn0003373 - protein_coding_gene extracellular matrix structural constituent ; GO:0005201 | inferred from sequence model cellular response to ecdysone ; GO:0071390 | inferred from direct assay extracellular matrix ; GO:0031012 | inferred from sequence model "Sgs3, sgs3, Sgs-3, sgs-3, Sgs, SGS378, DMSGS378, SGS-3, 68C GII, CG11720, Muc68Cb, Glue" - CG11720 27-Aug-18 DroID_v2018_08 - Scer\SED1 Cele\Y43F8C.16 - - - larval stage | third instar embryonic/larval salivary gland

larval stage | late third instar larval stage embryonic/larval salivary gland

electrophoretic variant FBgn0002661 mat(2)cell-J maternal effect cellularisation defect J http://flybase.org/reports/FBgn0002661 - gene molecular_function ; GO:0003674 | no biological data available cellularization ; GO:0007349 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "mat(2)cellRE43, mat(2)cell-J" - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "stage 5 embryo,maternal effect,embryonic/first instar larval cuticle" FBgn0037625 CG11768 - http://flybase.org/reports/FBgn0037625 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG11768 - CG11768 27-Aug-18 DroID_v2018_08 - Scer\YPR148C Cele\sup-36 - - Hsap\ACTC1 "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0035257 CG12011 - http://flybase.org/reports/FBgn0035257 protein_coding_gene - - - "clone 1.72, anon-EST:Liang-1.72, CG12011" - CG12011 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC08219 K -0.32963451 -0.354516878 -0.780871222 -0.318181204 1.533812185 -0.083838661 FBgn0051859 CG31859 - http://flybase.org/reports/FBgn0051859 protein_coding_gene - - - CG31859 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0028984 Spn88Ea Serpin 88Ea http://flybase.org/reports/FBgn0028984 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from biological aspect of ancestor with PANTHER:PTN000156122 negative regulation of Toll signaling pathway ; GO:0045751 | inferred from mutant phenotype imaginal disc-derived wing expansion ; GO:0048526 | inferred from mutant phenotype negative regulation of proteolysis ; GO:0045861 | inferred from sequence model extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000156122 extracellular region ; GO:0005576 | inferred from direct assay "CG18525, sp5, Sp5, spn5, Spn88Ea, Spn5" "IPR000215:Serpin family, IPR023795:Serpin, conserved site, IPR023796:Serpin domain" CG18525 27-Aug-18 DroID_v2018_08 "Drer\serpind1, Drer\serpinb1l3, Drer\serpinf2b, Drer\serping1, Drer\agt, Drer\serpini1, Drer\serpinb1l2, Drer\serpinf1, Drer\zgc:173729, Drer\serpinf2a, Drer\serpinb1" - "Cele\srp-8, Cele\srp-7, Cele\srp-1, Cele\srp-2, Cele\srp-3, Cele\srp-6, Cele\C28G1.2" - "Mmus\Serpinb6b, Mmus\Serpinb3a, Mmus\Serpinb3c, Mmus\Serpinb3b, Mmus\Serpinb1a, Mmus\Serpinf1, Mmus\Serpinb6a, Mmus\Serpini2, Mmus\Serpind1, Mmus\Serpinb7, Mmus\Serpinb1b, Mmus\Serpinb3d, Mmus\Serpinb11, Mmus\Serpinf2, Mmus\Serpinb1c, Mmus\Serpini1, Mmus\Serpinb9c, Mmus\Agt" "Hsap\SERPINB1, Hsap\SERPINF2, Hsap\SERPINI2, Hsap\SERPINB3, Hsap\SERPINB6, Hsap\SERPINB7, Hsap\SERPINB4, Hsap\AGT, Hsap\SERPINF1, Hsap\SERPINI1, Hsap\SERPIND1" "short lived,viable" wing FBgn0065741 l(2)SH0526 lethal (2) SH0526 http://flybase.org/reports/FBgn0065741 gene - - - "l(2)SH0526, l(2)SH2 0526" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0040081 p88 p88 http://flybase.org/reports/FBgn0040081 gene - - - p88 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038051 CG17207 - http://flybase.org/reports/FBgn0038051 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002995 cellular_component ; GO:0005575 | no biological data available "BcDNA:AT11646, CG17207" IPR002995:Surfeit locus 4 CG17207 27-Aug-18 DroID_v2018_08 "Drer\surf4l, Drer\surf4" Scer\ERV29 "Cele\sft-4, Cele\T02E1.7" "Xtro\surf4.2, Xtro\surf4.1" Mmus\Surf4 Hsap\SURF4 FBgn0035272 mRpL46 mitochondrial ribosomal protein L46 http://flybase.org/reports/FBgn0035272 protein_coding_gene "hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR000086, InterPro:IPR015797 structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:Q9H2W6 structural constituent of ribosome ; GO:0003735 | traceable author statement" mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial translation ; GO:0032543 | inferred by curator from GO:0005762 mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with UniProtKB:Q9H2W6 "MRP-L46, CG13922, mRpL46, MRpL46" "IPR000086:NUDIX hydrolase domain, IPR015797:NUDIX hydrolase domain-like, IPR021757:Ribosomal protein L46, IPR033650:Mitochondrial ribosomal protein L46 NUDIX" CG13922 27-Aug-18 DroID_v2018_08 Drer\mrpl46 Scer\MRPL17 Cele\mrpl-46 Xtro\mrpl46 Mmus\Mrpl46 Hsap\MRPL46 "viable,visible" trichogen cell DRSC08391 I -1.674590583 -1.322617881 -0.691824449 -1.236825347 0.810337925 -0.452405536 FBgn0036081 CG6559 - http://flybase.org/reports/FBgn0036081 protein_coding_gene - - - CG6559 - - 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0085691 CG41560 - http://flybase.org/reports/FBgn0085691 protein_coding_gene - - - CG41560 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0020818 l(3)98Dl lethal (3) 98Dl http://flybase.org/reports/FBgn0020818 - gene - - - l(3)98Dl - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264616 lncRNA:CR43956 - http://flybase.org/reports/FBgn0264616 non_protein_coding_gene - - - CR43956 - CR43956 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0013395 anon-64Bc anon-64Bc http://flybase.org/reports/FBgn0013395 - gene - - - anon-64Bc - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0013520 l(1)rp3 lethal (1) rp3 http://flybase.org/reports/FBgn0013520 - gene - - - l(1)rp3 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,polyphasic,recessive" FBgn0082340 HM56 HM56 http://flybase.org/reports/FBgn0082340 gene - - - HM56 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005374 x4 x4 http://flybase.org/reports/FBgn0005374 - gene - - - x4 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065923 l(2)SH0152 lethal (2) SH0152 http://flybase.org/reports/FBgn0065923 gene - - - l(2)SH0152 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0027866 CG9776 - http://flybase.org/reports/FBgn0027866 FBan0009776 protein_coding_gene - - - "BcDNA:LD19168, CG9776" - CG9776 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-195b21.5, Drer\znf318" - "Cele\K08D8.4, Cele\D1044.6" - Mmus\Zfp318 Hsap\ZNF318 "viable,visible" trichogen cell FBgn0264712 CG1172 - http://flybase.org/reports/FBgn0264712 protein_coding_gene ubiquitin binding ; GO:0043130 | inferred from electronic annotation with InterPro:IPR032752 molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG1172, CR43473, CC1172" "IPR032752:Ubiquitin-binding domain, IPR000626:Ubiquitin domain, IPR029071:Ubiquitin-related domain" CG1172 27-Aug-18 DroID_v2018_08 "Drer\ubtd2, Drer\ubtd1a, Drer\ubtd1b" - - "Xtro\ubtd2, Xtro\ubtd1" "Mmus\Ubtd2, Mmus\Ubtd1" "Hsap\UBTD2, Hsap\UBTD1" FBgn0001724 l(1)ESHS45 lethal (1) ESHS45 http://flybase.org/reports/FBgn0001724 - gene - - - l(1)ESHS45 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0000389 Cu-3 Curled 3 http://flybase.org/reports/FBgn0000389 - gene - - - "Cur, Cu-3" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,visible,dominant" wing FBgn0052066 CG32066 - http://flybase.org/reports/FBgn0052066 protein_coding_gene - - perivitelline space ; GO:0098595 | inferred from direct assay "CG6491, CG6487, CG32066" "IPR009828:Protein of unknown function DUF1394, IPR011989:Armadillo-like helical" CG32066 27-Aug-18 DroID_v2018_08 "Drer\znf395, Drer\fam49bb, Drer\fam49ba, Drer\fam49a" - Cele\R07G3.8 "Xtro\fam49b, Xtro\fam49a, Xtro\LOC548655" "Mmus\Fam49a, Mmus\Fam49b" "Hsap\FAM49A, Hsap\FAM49B" "viable,fertile" FBgn0062604 Mod(var)1429 Mod(var)1429 http://flybase.org/reports/FBgn0062604 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1429, Mod(var)1429" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation" FBgn0013529 l(2)23AB7 lethal (2) 23AB7 http://flybase.org/reports/FBgn0013529 - gene - - - l(2)23AB7 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0033943 CG12869 - http://flybase.org/reports/FBgn0033943 protein_coding_gene neurexin family protein binding ; GO:0042043 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 carboxylic ester hydrolase activity ; GO:0052689 | inferred from biological aspect of ancestor with PANTHER:PTN000168392 receptor activity ; GO:0004872 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 neuron cell-cell adhesion ; GO:0007158 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 modulation of synaptic transmission ; GO:0050804 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 synapse assembly ; GO:0007416 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 cell surface ; GO:0009986 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 synapse ; GO:0045202 | inferred from biological aspect of ancestor with PANTHER:PTN000168538 CG12869 "IPR002018:Carboxylesterase, type B, IPR019819:Carboxylesterase type B, conserved site, IPR029058:Alpha/Beta hydrolase fold" CG12869 27-Aug-18 DroID_v2018_08 "Drer\nlgn2b, Drer\si:ch211-93f2.1, Drer\nlgn2a, Drer\nlgn1, Drer\nlgn4a, Drer\nlgn3a, Drer\nlgn3b, Drer\cell, Drer\ces2, Drer\ces3, Drer\cel.1, Drer\nlgn4b" - "Cele\T22D1.11, Cele\W02B12.4, Cele\C23H4.4, Cele\ZC376.3, Cele\ZC376.1, Cele\ZC376.2, Cele\C17H12.4, Cele\T02B5.1, Cele\C01B10.10, Cele\glit-1, Cele\T07H6.1, Cele\ZK994.1, Cele\C23H4.7, Cele\T02B5.3, Cele\E01G6.3, Cele\C23H4.2, Cele\C23H4.3, Cele\C01B10.4, Cele\Y75B8A.3, Cele\nlg-1, Cele\C42D4.2" "Xtro\nlgn4x, Xtro\LOC100494782, Xtro\nlgn3, Xtro\cel, Xtro\nlgn2, Xtro\ces2, Xtro\ces3" "Mmus\Ces1h, Mmus\Ces1e, Mmus\Ces2g, Mmus\Nlgn1, Mmus\Ces2h, Mmus\Nlgn3, Mmus\Ces2b, Mmus\Ces3b, Mmus\Ces1d, Mmus\Ces1f, Mmus\Ces3a, Mmus\Ces1g, Mmus\Ces4a, Mmus\Ces2c, Mmus\Cel, Mmus\Ces1c, Mmus\Ces2a, Mmus\Ces2f, Mmus\Ces2e, Mmus\Nlgn2, Mmus\Ces5a, Mmus\Ces1b" "Hsap\CES3, Hsap\CES1, Hsap\CES4A, Hsap\CES5A, Hsap\NLGN1, Hsap\NLGN4X, Hsap\CES2, Hsap\NLGN4Y, Hsap\NLGN2, Hsap\CEL, Hsap\NLGN3" "viable,fertile" FBgn0266800 lncRNA:CR45262 - http://flybase.org/reports/FBgn0266800 non_protein_coding_gene - - - CR45262 - CR45262 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033340 CG13751 - http://flybase.org/reports/FBgn0033340 protein_coding_gene - - - "BcDNA:RH09719, CG13751" - CG13751 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0033149 CG11060 - http://flybase.org/reports/FBgn0033149 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG11060 "IPR032707:MYCBP-associated protein, IPR013783:Immunoglobulin-like fold" CG11060 27-Aug-18 DroID_v2018_08 Drer\mycbpap - - Xtro\mycbpap Mmus\Mycbpap Hsap\MYCBPAP viable FBgn0061071 l(3)S018310b lethal (3) S018310b http://flybase.org/reports/FBgn0061071 gene - - - "0183/10, l(3)S018310b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0001336 l(1)1Af lethal (1) 1Af http://flybase.org/reports/FBgn0001336 - gene - - - l(1)1Af - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0085213 CG34184 - http://flybase.org/reports/FBgn0085213 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34184 IPR006631:Protein of unknown function DM4/12 CG34184 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262983 CG43291 - http://flybase.org/reports/FBgn0262983 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43291 "IPR031986:Serine protease gd, N-terminal domain" CG43291 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259609 B1501 - http://flybase.org/reports/FBgn0259609 gene - - - B1501 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "tarsal segment,mediproboscis,proboscis" FBgn0263143 vret vreteno http://flybase.org/reports/FBgn0263143 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with fs(1)Yb inferred from physical interaction with Hsp27 inferred from physical interaction with piwi inferred from physical interaction with CG9281 inferred from physical interaction with BoYb inferred from physical interaction with armi inferred from physical interaction with SoYb "regulation of gene silencing by RNA ; GO:0060966 | inferred from mutant phenotype negative regulation of transposition, RNA-mediated ; GO:0010526 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype piRNA metabolic process ; GO:0034587 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype" P granule ; GO:0043186 | inferred from direct assay Yb body ; GO:0070725 | inferred from physical interaction with fs(1)Yb inferred from physical interaction with armi cytoplasm ; GO:0005737 | inferred from direct assay "CG4771, vret" IPR002999:Tudor domain CG4771 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0061063 l(3)S022122b lethal (3) S022122b http://flybase.org/reports/FBgn0061063 gene - - - "0221/22, l(3)S022122b" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0085236 CG34207 - http://flybase.org/reports/FBgn0085236 protein_coding_gene - - - CG34207 - CG34207 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0011957 tRNA:Arg-ACG-1-2 transfer RNA:Arginine-ACG 1-2 http://flybase.org/reports/FBgn0011957 "FBgn0003757, FBgn0011947, FBgn0050306, FBgn0050512, FBgn0060090" tRNA_gene CGU codon-amino acid adaptor activity ; GO:0033429 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033429 cytosol ; GO:0005829 | inferred by curator from GO:0033429 "Arg-tRNA, tRNA[arg], tRNA[Arg][[2]], AE002769.trna12-ArgACG, tRNA:R1, tRNA:arg1, tRNA:R:ACG:AE002769-c, tRNA:arg2:42Ac, CR30306, CR30512, chr2R.trna3-ArgACG, tRNA-Arg-ACG-1-2, tRNA:Arg-ACG-1-2, tRNA:R2:42Ac, CGU" - CR30512 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0010693 l(2)s4199 lethal (2) s4199 http://flybase.org/reports/FBgn0010693 - gene - - - l(2)s4199 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0259341 C192 - http://flybase.org/reports/FBgn0259341 gene - - - C192 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing,wing vein" FBgn0261068 LSm7 Like Sm 7 http://flybase.org/reports/FBgn0261068 protein_coding_gene RNA binding ; GO:0003723 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000058283 RNA binding ; GO:0003723 | contributes_to inferred from sequence or structural similarity with SGD:S000005091 "nuclear-transcribed mRNA catabolic process ; GO:0000956 | inferred from electronic annotation with InterPro:IPR017132 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000005091 inferred from sequence or structural similarity with protein_id:AAD56231 neurogenesis ; GO:0022008 | inferred from mutant phenotype RNA processing ; GO:0006396 | inferred from biological aspect of ancestor with PANTHER:PTN000058283" Lsm1-7-Pat1 complex ; GO:1990726 | inferred from biological aspect of ancestor with PANTHER:PTN000058361 U12-type spliceosomal complex ; GO:0005689 | inferred from biological aspect of ancestor with PANTHER:PTN000058284 U6 snRNP ; GO:0005688 | inferred from sequence or structural similarity with SGD:S000005091 U6 snRNP ; GO:0005688 | inferred from biological aspect of ancestor with PANTHER:PTN000058361 U2-type prespliceosome ; GO:0071004 | inferred from biological aspect of ancestor with PANTHER:PTN000058284 precatalytic spliceosome ; GO:0071011 | inferred from direct assay spliceosomal tri-snRNP complex ; GO:0097526 | inferred from biological aspect of ancestor with PANTHER:PTN000058361 catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "CG13277, LSm7, BcDNA:RH73529" "IPR001163:LSM domain, eukaryotic/archaea-type, IPR010920:LSM domain, IPR017132:Sm-like protein Lsm7" CG13277 27-Aug-18 DroID_v2018_08 "Drer\lsm7, Drer\snrpg" Scer\LSM7 Cele\lsm-7 "Xtro\snrpg, Xtro\lsm7" "Mmus\Snrpg, Mmus\Lsm7" "Hsap\SNRPG, Hsap\LSM7" DRSC02251 K 0.204611123 1.229106634 0.286358835 1.460116065 -1.720146305 0.118562524 FBgn0000943 fs(2)A13 female sterile (2) A13 http://flybase.org/reports/FBgn0000943 - gene - - - fs(2)A13 - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive,lethal,maternal effect" "female reproductive system,maternal effect,spindle | maternal effect" FBgn0036044 Zasp67 Z band alternatively spliced PDZ-motif protein 67 http://flybase.org/reports/FBgn0036044 protein_coding_gene - myofibril assembly ; GO:0030239 | inferred from mutant phenotype - "CG14168, Zasp67" "IPR017351:LIM and senescent cell antigen-like-containing domain protein 1, IPR001478:PDZ domain" CG14168 27-Aug-18 DroID_v2018_08 "Drer\lims2, Drer\lims1" - "Cele\pin-2, Cele\unc-97" Xtro\pdlim7 "Mmus\Lims1, Mmus\Pdlim2, Mmus\Pdlim7, Mmus\Lims2" "Hsap\LIMS4, Hsap\LIMS3, Hsap\PDLIM2, Hsap\LIMS2, Hsap\LIMS1" "viable,flight defective" FBgn0259276 EP-67 - http://flybase.org/reports/FBgn0259276 gene - - - EP-67 - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,planar polarity defective,lethal" wing FBgn0015426 l(1)1CDc lethal (1) 1CDc http://flybase.org/reports/FBgn0015426 - gene - - - l(1)1CDc - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0010052 Jhe Juvenile hormone esterase http://flybase.org/reports/FBgn0010052 FBgn0034077 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with CG3776 carboxylic ester hydrolase activity ; GO:0052689 | inferred from direct assay juvenile-hormone esterase activity ; GO:0004453 | inferred from direct assay juvenile hormone catabolic process ; GO:0006719 | inferred from direct assay male mating behavior ; GO:0060179 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from direct assay "JHE, CG8425, JH, Jhe, jhe, DmJhe" "IPR002018:Carboxylesterase, type B, IPR019819:Carboxylesterase type B, conserved site, IPR019826:Carboxylesterase type B, active site, IPR029058:Alpha/Beta hydrolase fold" CG8425 27-Aug-18 DroID_v2018_08 "Drer\nlgn4a, Drer\nlgn4b, Drer\nlgn3b, Drer\si:ch211-93f2.1, Drer\nlgn2a, Drer\nlgn1, Drer\ces3, Drer\nlgn2b, Drer\cel.1, Drer\nlgn3a, Drer\ces2, Drer\cell" - "Cele\T28C12.5, Cele\F13H6.3, Cele\C52A10.1, Cele\C52A10.2, Cele\K11G9.2, Cele\Y71H2AM.13, Cele\F15A8.6, Cele\F07C4.12, Cele\K07C11.4, Cele\K11G9.3, Cele\K11G9.1, Cele\F56C11.6, Cele\T28C12.4, Cele\T07H6.1, Cele\B0238.1, Cele\ges-1, Cele\glit-1, Cele\R173.3" "Xtro\cel, Xtro\nlgn2, Xtro\nlgn3, Xtro\ces3, Xtro\ces2, Xtro\LOC100494782, Xtro\nlgn4x" "Mmus\Ces1h, Mmus\Ces5a, Mmus\Ces2g, Mmus\Ces1g, Mmus\Ces2h, Mmus\Nlgn1, Mmus\Ces1e, Mmus\Ces2f, Mmus\Nlgn3, Mmus\Cel, Mmus\Nlgn2, Mmus\Ces2a, Mmus\Ces3a, Mmus\Ces1d, Mmus\Ces1c, Mmus\Ces4a, Mmus\Tg, Mmus\Ces2e, Mmus\Ces2c, Mmus\Ces1b, Mmus\Ces1f, Mmus\Ces2b, Mmus\Ces3b" "Hsap\NLGN2, Hsap\CES3, Hsap\NLGN4Y, Hsap\CES2, Hsap\NLGN3, Hsap\CES5A, Hsap\CEL, Hsap\TG, Hsap\NLGN1, Hsap\NLGN4X, Hsap\CES1, Hsap\CES4A" "viable,mating defective,male,recessive,hyperactive,conditional,chemical resistant" FBgn0034644 CG10082 - http://flybase.org/reports/FBgn0034644 protein_coding_gene "inositol-1,4,5-trisphosphate 3-kinase activity ; GO:0008440 | inferred from electronic annotation with InterPro:IPR005522" - - "anon-WO0172774.149, CG10082, dmIP6K" "IPR005522:Inositol polyphosphate kinase, IPR015943:WD40/YVTN repeat-like-containing domain" CG10082 27-Aug-18 DroID_v2018_08 "Drer\ip6k2b, Drer\ip6k1, Drer\ipmkb, Drer\ip6k2a" "Scer\ARG82, Scer\KCS1" "Cele\ZK795.1, Cele\F30A10.3, Cele\Y22D7AR.6, Cele\T20F7.3" "Xtro\ip6k2, Xtro\ip6k1" "Mmus\Ip6k2, Mmus\Ip6k3, Mmus\Ip6k1, Mmus\Ipmk" "Hsap\IPMK, Hsap\IP6K2, Hsap\IP6K3, Hsap\IP6K1" "viable,partially lethal - majority die,recessive" DRSC04054 K 0.560440401 -0.962290212 -0.141540065 0.845679138 0.099701232 1.524920336 FBgn0031134 CG1314 - http://flybase.org/reports/FBgn0031134 protein_coding_gene - - - "anon-WO0140519.251, CG1314" IPR031732:Protein of unknown function DUF4729 CG1314 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0259962 Sfp33A1 Seminal fluid protein 33A1 http://flybase.org/reports/FBgn0259962 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "Sfp33A1, CG42472" - CG42472 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0025768 l(3)89Ch lethal (3) 89Ch http://flybase.org/reports/FBgn0025768 - gene - - - "l(3)M2912, l(3)89Ch" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0034626 CG10795 - http://flybase.org/reports/FBgn0034626 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "LD27358, CG10795" IPR007829:TM2 domain CG10795 27-Aug-18 DroID_v2018_08 "Drer\LOC100535396, Drer\LOC797974, Drer\tm2d1, Drer\si:dkey-229d11.5, Drer\slc2a6, Drer\si:ch1073-263o8.2, Drer\slc2a8" - "Cele\M01G12.9, Cele\Y66D12A.21, Cele\ZK858.5, Cele\M01G12.14, Cele\C41D11.9" "Xtro\slc2a6, Xtro\tm2d1, Xtro\slc2a8" "Mmus\Slc2a8, Mmus\Acrv1, Mmus\Pate1, Mmus\Pate4, Mmus\Gm7257, Mmus\1700013H16Rik, Mmus\Gm5615, Mmus\Slc2a6, Mmus\Tm2d1, Mmus\Gm17689, Mmus\Pate3" "Hsap\ACRV1, Hsap\PATE1, Hsap\SLC2A6, Hsap\PATE4, Hsap\TM2D1, Hsap\PATE3, Hsap\SLC2A8" viable FBgn0262945 lncRNA:CR43264 - http://flybase.org/reports/FBgn0262945 non_protein_coding_gene - - - CR43264 - CR43264 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262467 Scox Synthesis of cytochrome c oxidase http://flybase.org/reports/FBgn0262467 protein_coding_gene copper chaperone activity ; GO:0016531 | inferred from sequence or structural similarity with UniProt:O75880 inferred from sequence or structural similarity with UniProtKB:O43819 cytochrome-c oxidase activity ; GO:0004129 | inferred from mutant phenotype copper ion transport ; GO:0006825 | inferred from electronic annotation with InterPro:IPR017276 cellular copper ion homeostasis ; GO:0006878 | inferred from electronic annotation with InterPro:IPR017276 cytochrome complex assembly ; GO:0017004 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype flight ; GO:0060361 | inferred from mutant phenotype oocyte construction ; GO:0007308 | inferred from mutant phenotype photoreceptor cell maintenance ; GO:0045494 | inferred from mutant phenotype phototransduction ; GO:0007602 | inferred from mutant phenotype respiratory chain complex IV assembly ; GO:0008535 | inferred from sequence or structural similarity with UniProt:O75880 inferred from sequence or structural similarity with UniProtKB:O43819 positive regulation of ATP biosynthetic process ; GO:2001171 | inferred from mutant phenotype locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype instar larval development ; GO:0002168 | inferred from mutant phenotype mitochondrial inner membrane ; GO:0005743 | inferred from electronic annotation with InterPro:IPR017276 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProt:O75880 inferred from sequence or structural similarity with UniProtKB:O43819 "CG8885, Scox, SCO, scox, SCOX, dSco1, l(2)SH1783, l(2)SH2 1783, SCO1" "IPR003782:Copper chaperone SCO1/SenC, IPR012336:Thioredoxin-like fold, IPR017276:Synthesis of cytochrome c oxidase, Sco1/Sco2" CG8885 27-Aug-18 DroID_v2018_08 "Drer\sco2, Drer\sco1" "Scer\SCO2, Scer\SCO1" "Cele\C06C3.8, Cele\T10B5.7, Cele\C41H7.4, Cele\C14E2.6, Cele\sco-1, Cele\C08A9.6, Cele\Y51H4A.5, Cele\C41H7.6, Cele\C40H1.2, Cele\B0454.9" "Xtro\sco2, Xtro\pnliprp2, Xtro\sco1, Xtro\pnliprp3" "Mmus\Pnlip, Mmus\Pnliprp1, Mmus\Pnliprp2, Mmus\Sco2, Mmus\Sco1" "Hsap\PNLIPRP3, Hsap\SCO1, Hsap\PNLIP, Hsap\SCO2" DRSC03117 E -0.431363088 -0.263998782 -1.668874892 0.021571532 0.408687422 -0.590105257 FBgn0038365 CG9593 - http://flybase.org/reports/FBgn0038365 protein_coding_gene transmembrane receptor protein tyrosine kinase activator activity ; GO:0030297 | inferred from sequence or structural similarity with HGNC:487 negative regulation of apoptotic process ; GO:0043066 | inferred from sequence or structural similarity with HGNC:487 extracellular space ; GO:0005615 | inferred from sequence or structural similarity with HGNC:487 "CG9593, AAF55227, FBpp0082632" "IPR002181:Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain, IPR014716:Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1, IPR014715:Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2" CG9593 27-Aug-18 DroID_v2018_08 "Drer\si:zfos-2330d3.6, Drer\fgg, Drer\tnw, Drer\angptl6, Drer\angpt1, Drer\si:ch211-157b11.8, Drer\zgc:194887, Drer\LOC555374, Drer\wu:fj11g02, Drer\tnr, Drer\angpt2b, Drer\angpt2a, Drer\angptl3, Drer\zmp:0000000846, Drer\si:dkeyp-51b7.3, Drer\si:ch1073-110a20.2, Drer\fgl2b, Drer\tnxba, Drer\zgc:171687, Drer\angpt4, Drer\zgc:173915, Drer\tnc, Drer\LOC100334800, Drer\si:ch1073-110a20.3, Drer\LOC100007488, Drer\angptl5, Drer\mfap4, Drer\si:zfos-2330d3.1, Drer\si:zfos-2330d3.8, Drer\fndc7a, Drer\fgl1, Drer\si:ch1073-110a20.1, Drer\angptl2a, Drer\si:ch211-287a12.9, Drer\angptl1a, Drer\angptl4, Drer\angptl7, Drer\si:zfos-2330d3.3, Drer\angptl2b, Drer\fgl2a, Drer\fga, Drer\fgb, Drer\fibcd1" - "Cele\ensh-1, Cele\T15B7.1" "Xtro\fcn2, Xtro\tnc, Xtro\tnn, Xtro\LOC100488177, Xtro\angptl3, Xtro\fgb, Xtro\angptl2, Xtro\fgg, Xtro\tnr, Xtro\fcn1, Xtro\tnxb, Xtro\angptl4, Xtro\fgl1, Xtro\fgl2, Xtro\fga, Xtro\angptl5, Xtro\LOC100491105, Xtro\angpt4, Xtro\mfap4, Xtro\angpt1, Xtro\fibcd1, Xtro\LOC100497330, Xtro\fcn3" "Mmus\Mfap4, Mmus\Fgg, Mmus\Angptl1, Mmus\Fga, Mmus\Fgb, Mmus\Angptl2, Mmus\Tnn, Mmus\Fgl2, Mmus\Fgl1, Mmus\Tnr, Mmus\Tnc, Mmus\Fcna, Mmus\Angptl7, Mmus\Angptl4, Mmus\Angptl3, Mmus\Fcnb, Mmus\Angptl6, Mmus\Fibcd1, Mmus\Tnxb, Mmus\Angpt1, Mmus\Fndc7, Mmus\Angpt2, Mmus\Angpt4" "Hsap\FGA, Hsap\ANGPT4, Hsap\FCN1, Hsap\ANGPT2, Hsap\ANGPT1, Hsap\ANGPTL4, Hsap\FCN3, Hsap\FNDC7, Hsap\TNC, Hsap\FGB, Hsap\ANGPTL7, Hsap\FGL1, Hsap\FGG, Hsap\ANGPTL6, Hsap\ANGPTL1, Hsap\MFAP4, Hsap\FCN2, Hsap\ANGPTL3, Hsap\ANGPTL2, Hsap\FGL2, Hsap\ANGPTL5, Hsap\TNR, Hsap\TNN, Hsap\TNXB, Hsap\FIBCD1" viable FBgn0000500 Dsk Drosulfakinin http://flybase.org/reports/FBgn0000500 "FBan0018090, FBgn0037214, FBgn0062936" protein_coding_gene neuropeptide hormone activity ; GO:0005184 | non-traceable author statement neuropeptide receptor binding ; GO:0071855 | inferred from physical interaction with CCKLR-17D1 neuropeptide hormone activity ; GO:0005184 | inferred from direct assay neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype larval locomotory behavior ; GO:0008345 | inferred from direct assay inferred from mutant phenotype adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay adult feeding behavior ; GO:0008343 | inferred from mutant phenotype positive regulation of cytosolic calcium ion concentration ; GO:0007204 | inferred from direct assay regulation of smooth muscle contraction ; GO:0006940 | inferred from direct assay neuropeptide signaling pathway ; GO:0007218 | non-traceable author statement multicellular organismal response to stress ; GO:0033555 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred by curator from GO:0005184 "DSK, Drm-SK-2, Drm-SK-1, dsk, Drm-SK-0, DSK-I, CCK, DrmSK-II, DrmSK-I, CG18090, BcDNA:RH46857, Dsk, Drm-SK, SK-0, DSK I, DSK II, DSK-0, DSK-1, DSK-2, Drosulfakinin 1, Drosulfakinin 2" "IPR013152:Gastrin/cholecystokinin, conserved site" CG18090 27-Aug-18 DroID_v2018_08 - - - - - - adult stage protocerebrum

"neuroanatomy defective,neurophysiology defective,stress response defective,locomotor behavior defective,viable,fertile" "embryonic/larval neuromuscular junction,NMJ bouton,embryonic/larval neuromuscular junction | third instar larval stage,NMJ bouton | third instar larval stage" DRSC12347 K 1.205861528 -0.374293819 0.180803248 0.378568853 2.394881714 1.053449708 FBgn0264360 asRNA:CR43812 - http://flybase.org/reports/FBgn0264360 non_protein_coding_gene - - - CR43812 - CR43812 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040055 CG14474 - http://flybase.org/reports/FBgn0040055 protein_coding_gene - - - CG14474 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0029507 Tsp42Ed Tetraspanin 42Ed http://flybase.org/reports/FBgn0029507 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence model integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "CG12846, Dm.Tsp42Ed, GH07074, BcDNA:GH07074, Tsp42Ed, Tsp42E" "IPR018499:Tetraspanin/Peripherin, IPR018503:Tetraspanin, conserved site, IPR000301:Tetraspanin, IPR008952:Tetraspanin, EC2 domain" CG12846 27-Aug-18 DroID_v2018_08 Drer\cd63 - "Cele\tsp-13, Cele\tsp-14, Cele\tsp-7, Cele\tsp-3, Cele\tsp-1, Cele\tsp-2" Xtro\cd63 Mmus\Cd63 Hsap\CD63 FBgn0032110 CG3748 - http://flybase.org/reports/FBgn0032110 protein_coding_gene - - - "BcDNA:AT30262, anon-WO0140519.143, CG3748" "IPR003887:LEM domain, IPR011015:LEM/LEM-like domain" CG3748 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0038468 CG5225 - http://flybase.org/reports/FBgn0038468 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG5225 IPR008160:Collagen triple helix repeat CG5225 27-Aug-18 DroID_v2018_08 "Drer\si:dkeyp-44a8.4, Drer\c1qtnf7, Drer\col15a1b, Drer\c1qtnf2" - - - "Mmus\C1qtnf7, Mmus\C1qtnf2, Mmus\Col18a1" "Hsap\C1QTNF2, Hsap\C1QTNF7, Hsap\COL18A1" "viable,fertile" FBgn0019940 Rh6 Rhodopsin 6 http://flybase.org/reports/FBgn0019940 - protein_coding_gene G-protein coupled photoreceptor activity ; GO:0008020 | inferred from sequence or structural similarity with ninaE inferred from sequence or structural similarity with Rh2 inferred from sequence or structural similarity with Rh3 inferred from sequence or structural similarity with Rh4 G-protein coupled photoreceptor activity ; GO:0008020 | inferred from genetic interaction with ninaE G-protein coupled photoreceptor activity ; GO:0008020 | inferred from sequence or structural similarity G-protein coupled photoreceptor activity ; GO:0008020 | non-traceable author statement "visual perception ; GO:0007601 | inferred from electronic annotation with InterPro:IPR001760 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR001735, InterPro:IPR001760 entrainment of circadian clock by photoperiod ; GO:0043153 | inferred from genetic interaction with Rh5, cry inferred from genetic interaction with Rh5, cry, norpA inferred from genetic interaction with cry, norpA sensory perception of sound ; GO:0007605 | inferred from mutant phenotype phototransduction ; GO:0007602 | inferred from genetic interaction with ninaE phototransduction ; GO:0007602 | non-traceable author statement thermotaxis ; GO:0043052 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity phototransduction ; GO:0007602 | inferred from sequence or structural similarity with ninaE inferred from sequence or structural similarity with Rh2 inferred from sequence or structural similarity with Rh3 inferred from sequence or structural similarity with Rh4" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR001735, InterPro:IPR001760, InterPro:IPR017452 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity rhabdomere ; GO:0016028 | inferred from direct assay" "Rh6, rh6, Rh, RH6, DMELRH6, Dm Rh6, CG5192, R8" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR001735:Opsin RH1/RH2, IPR001760:Opsin, IPR017452:GPCR, rhodopsin-like, 7TM, IPR027430:Visual pigments (opsins) retinal binding site" CG5192 27-Aug-18 DroID_v2018_08 "Drer\tmtops2a, Drer\opn4.1, Drer\valopb, Drer\opn1lw1, Drer\tmtops2b, Drer\opn4b, Drer\rrh, Drer\opn1sw2, Drer\opn8b, Drer\tmtopsb, Drer\opn1mw1, Drer\opn1sw1, Drer\opn4a, Drer\tmtops3a, Drer\opn7a, Drer\rho, Drer\opn5, Drer\valopa, Drer\rgrb, Drer\exorh, Drer\opn1mw3, Drer\opn7b, Drer\opn8c, Drer\opn4xa, Drer\opn9, Drer\opn6a, Drer\opn6b, Drer\parapinopsinb, Drer\opn4xb, Drer\rgra, Drer\opn7c, Drer\rhol, Drer\opn1lw2, Drer\opn3, Drer\opn1mw4, Drer\tmtops3b, Drer\opn7d, Drer\parietopsin" - "Cele\sro-1, Cele\nmur-3" "Xtro\opn1sw, Xtro\LOC100485989, Xtro\tmtops, Xtro\LOC100124934, Xtro\rho, Xtro\LOC100485437, Xtro\rrh, Xtro\tmtops.2, Xtro\opn1lw, Xtro\opn5" "Mmus\Rgr, Mmus\Rrh, Mmus\Opn3, Mmus\Rho, Mmus\Opn1mw, Mmus\Opn4, Mmus\Opn5, Mmus\Opn1sw" "Hsap\OPN1SW, Hsap\RRH, Hsap\OPN1LW, Hsap\OPN4, Hsap\OPN3, Hsap\RGR, Hsap\OPN1MW, Hsap\OPN1MW3, Hsap\RHO, Hsap\OPN5, Hsap\OPN1MW2" adult stage " adult head

, photoreceptor cell R8 | subset

" "auditory perception defective,neurophysiology defective,viable" FBgn0053092 P5CDh2 delta-1-Pyrroline-5-carboxylate dehydrogenase 2 http://flybase.org/reports/FBgn0053092 protein_coding_gene "oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR015590, InterPro:IPR016161, InterPro:IPR016162" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR015590, InterPro:IPR016161, InterPro:IPR016162, InterPro:IPR016163" - "CG6670, P5CDh2, CG33092, DmP5CDh2" "IPR015590:Aldehyde dehydrogenase domain, IPR016161:Aldehyde/histidinol dehydrogenase, IPR016162:Aldehyde dehydrogenase N-terminal domain" CG33092 27-Aug-18 DroID_v2018_08 "Drer\iffo2a, Drer\aldh4a1, Drer\zgc:162898" Scer\PUT2 Cele\alh-6 Xtro\aldh4a1 "Mmus\2300009A05Rik, Mmus\Aldh4a1, Mmus\Iffo2" "Hsap\IFFO2, Hsap\C15orf61, Hsap\ALDH4A1" FBgn0265630 sno strawberry notch http://flybase.org/reports/FBgn0265630 protein_coding_gene - imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype Notch signaling pathway ; GO:0007219 | inferred from mutant phenotype inferred from genetic interaction with H inferred from genetic interaction with Su(H) positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from mutant phenotype nucleus ; GO:0005634 | traceable author statement nucleus ; GO:0005634 | inferred from direct assay "sno, CG1903, CG44436, Sno, g-l, l(1)11Ea" "IPR026741:Protein strawberry notch, IPR026937:Strawberry notch, helicase C domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG44436 27-Aug-18 DroID_v2018_08 "Drer\sbno1, Drer\sbno2a, Drer\si:ch73-63e15.2" - Cele\let-765 "Xtro\sbno2, Xtro\sbno1" "Mmus\Sbno2, Mmus\Sbno1" "Hsap\SBNO2, Hsap\SBNO1" " larval stage , embryonic stage , adult stage && oogenesis stage , embryonic stage | stage 8 " " ventral thoracic disc | ubiquitous

, epidermis

, eye disc | ubiquitous

, embryonic central nervous system

, Malpighian tubule

, follicle cell

, dorsal mesothoracic disc | ubiquitous

, mesectoderm

, imaginal disc

" FBgn0084035 CG41475 - http://flybase.org/reports/FBgn0084035 protein_coding_gene - - - "CG41104, CG41103, CG41475" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266737 asRNA:CR45210 - http://flybase.org/reports/FBgn0266737 non_protein_coding_gene - - - CR45210 - CR45210 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0053116 CG33116 - http://flybase.org/reports/FBgn0053116 protein_coding_gene "phosphotransferase activity, for other substituted phosphate groups ; GO:0016780 | inferred from electronic annotation with InterPro:IPR000462" phospholipid biosynthetic process ; GO:0008654 | inferred from electronic annotation with InterPro:IPR000462 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR000462 "CG10355, CG33116, dCCS1" "IPR000462:CDP-alcohol phosphatidyltransferase, IPR014472:Choline/ethanolamine phosphotransferase" CG33116 27-Aug-18 DroID_v2018_08 "Drer\chpt1, Drer\cept1a, Drer\si:ch211-197l9.4, Drer\cept1b" "Scer\CPT1, Scer\EPT1" "Cele\F54D7.2, Cele\cept-2, Cele\cept-1" "Xtro\chpt1, Xtro\cept1, Xtro\ept1" "Mmus\Chpt1, Mmus\Selenoi, Mmus\Cept1" "Hsap\CEPT1, Hsap\CHPT1, Hsap\SELENOI" "viable,visible" "chaeta,supernumerary" FBgn0037994 eIF3d2 eukaryotic translation initiation factor 3 subunit d2 http://flybase.org/reports/FBgn0037994 protein_coding_gene translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity inferred from sequence or structural similarity with protein_id:BAA25327 translation initiation factor activity ; GO:0003743 | inferred from biological aspect of ancestor with PANTHER:PTN000273956 translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity with UniProtKB:Q9VCK0 translational initiation ; GO:0006413 | inferred from sequence or structural similarity regulation of translational initiation ; GO:0006446 | inferred from sequence or structural similarity with UniProtKB:Q9VCK0 eukaryotic translation initiation factor 3 complex ; GO:0005852 | inferred from sequence or structural similarity with UniProtKB:Q9VCK0 eukaryotic translation initiation factor 3 complex ; GO:0005852 | inferred from biological aspect of ancestor with PANTHER:PTN000273956 eukaryotic translation initiation factor 3 complex ; GO:0005852 | inferred from sequence or structural similarity "149735_at, eIF3-S7, CG4810, eIF3d2" IPR007783:Eukaryotic translation initiation factor 3 subunit D CG4810 27-Aug-18 DroID_v2018_08 Drer\eif3d - Cele\eif-3.D Xtro\eif3d Mmus\Eif3d Hsap\EIF3D viable FBgn0004125 l(2)43Bd lethal (2) 43Bd http://flybase.org/reports/FBgn0004125 - gene - - - "43Bd, l(2)43Bd" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0041713 yellow-c yellow-c http://flybase.org/reports/FBgn0041713 protein_coding_gene - cuticle pigmentation ; GO:0048067 | inferred from biological aspect of ancestor with PANTHER:PTN000000448 melanin biosynthetic process ; GO:0042438 | inferred from biological aspect of ancestor with PANTHER:PTN000000448 - "CG4182, BG:DS00929.8, anon-EST:ParkEST125, yellow-c, yell-c" "IPR017996:Major royal jelly protein/protein yellow, IPR011042:Six-bladed beta-propeller, TolB-like" CG4182 27-Aug-18 DroID_v2018_08 Drer\dpm3 - "Cele\F49E11.8, Cele\T27A1.3, Cele\fbxa-76, Cele\C24H12.1" Xtro\dpm3 Mmus\Dpm3 Hsap\DPM3 FBgn0030819 CG8926 - http://flybase.org/reports/FBgn0030819 protein_coding_gene - - - CG8926 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040942 CG12643 - http://flybase.org/reports/FBgn0040942 protein_coding_gene - - - CG12643 - CG12643 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0058000 CG40000 - http://flybase.org/reports/FBgn0058000 protein_coding_gene - - - CG40000 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037796 CG12814 - http://flybase.org/reports/FBgn0037796 protein_coding_gene - - - "CG12815, CG12814" IPR001507:Zona pellucida domain CG12814 27-Aug-18 DroID_v2018_08 "Drer\zgc:153932, Drer\si:ch211-229d2.5, Drer\zmp:0000001031, Drer\si:ch211-103f14.3" - "Cele\cutl-4, Cele\cutl-24, Cele\cutl-14, Cele\cutl-15, Cele\cutl-1, Cele\cutl-13, Cele\cutl-10, Cele\cut-5, Cele\cutl-28, Cele\cut-1, Cele\cut-6, Cele\T01D1.8, Cele\cutl-2, Cele\cutl-5, Cele\cutl-25, Cele\ram-5, Cele\cutl-6, Cele\cutl-20, Cele\cutl-11, Cele\cutl-9, Cele\cutl-22, Cele\cutl-12, Cele\cutl-8, Cele\cutl-29, Cele\cutl-26, Cele\dpy-1, Cele\cutl-7, Cele\cut-3, Cele\cutl-16, Cele\cut-4, Cele\F46G11.6, Cele\cutl-19, Cele\cutl-3" "Xtro\MGC89178, Xtro\thdl18, Xtro\thdl17" - - viable FBgn0259658 B1509 - http://flybase.org/reports/FBgn0259658 gene - - - B1509 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "tarsal segment,unguis,antennal segment,arista,wing,scutellum" FBgn0060607 l(3)S090605 lethal (3) S090605 http://flybase.org/reports/FBgn0060607 gene - - - "0906/05, l(3)S090605" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0262969 lncRNA:CR43280 - http://flybase.org/reports/FBgn0262969 non_protein_coding_gene - - - "CR43280, lincRNA.605" - CR43280 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0014066 Su(tor)3-333 Su(tor)3-333 http://flybase.org/reports/FBgn0014066 - gene - - - Su(tor)3-333 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267073 lncRNA:CR45517 - http://flybase.org/reports/FBgn0267073 non_protein_coding_gene - - - CR45517 - CR45517 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0064172 l(2)c855 lethal (2) c855 http://flybase.org/reports/FBgn0064172 gene - - - l(2)c855 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0024609 olfJ106 olfactory J106 http://flybase.org/reports/FBgn0024609 - gene - - - olfJ106 - - 27-Aug-18 DroID_v2018_08 - - - - - - smell perception defective FBgn0082614 Su(PDS)P80 Su(PDS)P80 http://flybase.org/reports/FBgn0082614 gene - - - Su(PDS)P80 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,non-suppressor of variegation" FBgn0040330 EY2-8 EY2-8 http://flybase.org/reports/FBgn0040330 gene - - - EY2-8 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0010066 M(3)32l M(3)32l http://flybase.org/reports/FBgn0010066 - gene - - - M(3)32l - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036847 CNPYb - http://flybase.org/reports/FBgn0036847 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - endomembrane system ; GO:0012505 | inferred from direct assay "anon-WO0118547.323, CG11577" IPR021852:Domain of unknown function DUF3456 CG11577 27-Aug-18 DroID_v2018_08 "Drer\tnrc5, Drer\cnpy4" - Cele\C11H1.7 - "Mmus\Cnpy3, Mmus\Cnpy4" "Hsap\CNPY4, Hsap\CNPY3" viable FBgn0016968 wan wanderer http://flybase.org/reports/FBgn0016968 - gene - peripheral nervous system development ; GO:0007422 | traceable author statement - wan - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" peripheral nervous system FBgn0264552 CG43931 - http://flybase.org/reports/FBgn0264552 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43931 - CG43931 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0086446 DCTN6-p27 "Dynactin 6, p27 subunit" http://flybase.org/reports/FBgn0086446 protein_coding_gene - microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity dynactin complex ; GO:0005869 | inferred from electronic annotation with InterPro:IPR027777 dynactin complex ; GO:0005869 | inferred from sequence or structural similarity "l(2)37Ce, CG17347, Ce, l(2)E62, l(2)37Ce)E62, DCTN6, DCTN6-p27, P27" "IPR011004:Trimeric LpxA-like, IPR001451:Hexapeptide repeat, IPR027777:Dynactin subunit 6" CG17347 27-Aug-18 DroID_v2018_08 Drer\zgc:112102 - Cele\dnc-6 Xtro\dctn6 Mmus\Dctn6 Hsap\DCTN6 FBgn0004559 Su(var)308 Suppressor of variegation 308 http://flybase.org/reports/FBgn0004559 - gene - - - Su(var)308 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032730 CG10431 - http://flybase.org/reports/FBgn0032730 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR006612, InterPro:IPR013087 RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN000003381" "transcription, DNA-templated ; GO:0006351 | inferred from electronic annotation with InterPro:IPR027775 dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000003381 "dmCG10431, CG10431" "IPR006612:Zinc finger, C2CH-type, IPR012934:Zinc finger, AD-type, IPR027775:C2H2- zinc finger protein family subset, IPR013087:Zinc finger C2H2-type" CG10431 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-40k21.9, Drer\thap1, Drer\si:dkey-228b2.6, Drer\zgc:113364, Drer\thap7, Drer\thap3, Drer\zgc:163143, Drer\arl14ep, Drer\LOC101882293, Drer\si:ch73-389k6.1" Scer\RPN4 - "Xtro\thap7, Xtro\thap5, Xtro\sall1, Xtro\thap1" "Mmus\Zkscan6, Mmus\Zfp446, Mmus\Zfp641, Mmus\Zfp174, Mmus\Thap3, Mmus\Zscan29, Mmus\Thap2, Mmus\Zfp444, Mmus\Thap1, Mmus\Zfp202, Mmus\Thap7, Mmus\Zscan18, Mmus\Zscan5b, Mmus\Zkscan17, Mmus\Zkscan2, Mmus\Zfp369, Mmus\Zfp110" "Hsap\ZNF641, Hsap\ZKSCAN2, Hsap\THAP8, Hsap\ZSCAN32, Hsap\ZNF496, Hsap\ZNF174, Hsap\THAP7, Hsap\ZNF202, Hsap\ZNF446, Hsap\PEG3, Hsap\ZNF18, Hsap\THAP5, Hsap\THAP3, Hsap\ZSCAN1, Hsap\ZSCAN29, Hsap\THAP2, Hsap\ZSCAN5A, Hsap\ZSCAN18, Hsap\ZNF444, Hsap\THAP1, Hsap\THAP6, Hsap\ZSCAN5B" "viable,neuroanatomy defective" "dorsal multidendritic neuron ddaD,dorsal multidendritic neuron ddaC" FBgn0085501 CG40609 - http://flybase.org/reports/FBgn0085501 protein_coding_gene - - - CG40609 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040711 CG15409 - http://flybase.org/reports/FBgn0040711 protein_coding_gene - - - CG15409 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005180 l(2)S3 lethal of Seto 3 http://flybase.org/reports/FBgn0005180 - gene - - - l(2)S3 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of prepupal stage,some die during prepupal stage,recessive" "puparium,prepupa,pupal tracheal system" FBgn0052421 tRNA:Val-TAC-1-2 transfer RNA:Valine-TAC 1-2 http://flybase.org/reports/FBgn0052421 tRNA_gene GUA codon-amino acid adaptor activity ; GO:0033451 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033451 cytosol ; GO:0005829 | inferred by curator from GO:0033451 "AE002602.trna12-ValTAC, valine tRNA, tRNA[Val][[3a]], tRNA:val3a:64D, tRNA:V3a:64D, tRNA:V3a, tRNA:V:TAC:AE002602-a, CR32421, chr3L.trna46-ValTAC, tRNA-Val[UAC], tRNA:Val-TAC-1-2, tRNA:CR32421, tRNA-Val-TAC-1-2, GUA" - CR32421 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0061111 l(3)S006615 lethal (3) S006615 http://flybase.org/reports/FBgn0061111 gene - - - "0066/15, l(3)S006615" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0052603 CG32603 - http://flybase.org/reports/FBgn0052603 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32603 IPR022727:Pupal cuticle protein C1 CG32603 27-Aug-18 DroID_v2018_08 "Drer\mdc1, Drer\pou2af1, Drer\zgc:174862" - Cele\abu-10 - "Mmus\Pou2af1, Mmus\Peg3, Mmus\Mdc1" "Hsap\POU2AF1, Hsap\PEG3" DRSC21586 E 0.49237136 0.341005411 0.575960863 1.838739213 1.426685488 -0.521452156 FBgn0021822 l(2)k16207 lethal (2) k16207 http://flybase.org/reports/FBgn0021822 - gene - - - l(2)k16207 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0065767 l(2)SH0471 lethal (2) SH0471 http://flybase.org/reports/FBgn0065767 gene - - - "l(2)SH0471, l(2)SH2 0471" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0024878 l(2)52Fc lethal (2) 52Fc http://flybase.org/reports/FBgn0024878 - gene - - - "D8.13, l(2)52Fc" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0065232 l(2)SH2169 lethal (2) SH2169 http://flybase.org/reports/FBgn0065232 gene - - - "l(2)SH2169, l(2)SH2 2169" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0033097 Zip42C.2 Zinc/iron regulated transporter-related protein 42C.2 http://flybase.org/reports/FBgn0033097 protein_coding_gene zinc ion transmembrane transporter activity ; GO:0005385 | inferred from direct assay zinc ion transmembrane transporter activity ; GO:0005385 | inferred by curator from GO:0016323 zinc II ion transmembrane import ; GO:0071578 | inferred from genetic interaction with Zip42C.1 detoxification of zinc ion ; GO:0010312 | inferred from mutant phenotype apical plasma membrane ; GO:0016324 | inferred from direct assay basolateral plasma membrane ; GO:0016323 | inferred from direct assay "dZip42C.2, dZip2, CG9430, Zip42C.2, cg9430, dZIP42C.2" IPR003689:Zinc/iron permease CG9430 27-Aug-18 DroID_v2018_08 "Drer\slc39a1, Drer\slc39a3" "Scer\ZRT2, Scer\ZRT1, Scer\WSS1" "Cele\F31C3.4, Cele\C06G8.3, Cele\F30B5.7, Cele\Y54G9A.4, Cele\C18A3.2, Cele\F55F8.9" "Xtro\slc39a3, Xtro\slc39a2, Xtro\slc39a1" "Mmus\Slc39a2, Mmus\Slc39a1, Mmus\Slc39a3" "Hsap\SLC39A3, Hsap\SLC39A2, Hsap\SLC39A1" "partially lethal - majority die,some die during pupal stage,lethal - all die during pupal stage,viable,lethal - all die during larval stage" FBgn0014324 l(3)ry3 lethal (3) ry3 http://flybase.org/reports/FBgn0014324 - gene - - - l(3)ry3 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0015995 l(2)k08807 lethal (2) k08807 http://flybase.org/reports/FBgn0015995 - gene - - - l(2)k08807 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" presumptive embryonic/larval peripheral nervous system FBgn0085440 Lgr4 Leucine-rich repeat-containing G protein-coupled receptor 4 http://flybase.org/reports/FBgn0085440 protein_coding_gene "G-protein coupled receptor activity ; GO:0004930 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR008112 neuropeptide receptor activity ; GO:0008188 | inferred from sequence model protein-hormone receptor activity ; GO:0016500 | inferred from sequence or structural similarity" G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR000276 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR017452 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from sequence model" "Lgr4, CG32637, anon-WO0170980.20, anon-WO0170980.19, CG4187, CG34411, DLGR4, dLGR4, lgr4" "IPR032675:Leucine-rich repeat domain, L domain-like, IPR023415:Low-density lipoprotein (LDL) receptor class A, conserved site, IPR000276:G protein-coupled receptor, rhodopsin-like, IPR001611:Leucine-rich repeat, IPR008112:Relaxin receptor, IPR017452:GPCR, rhodopsin-like, 7TM, IPR025875:Leucine rich repeat 4, IPR034298:TSH/LHCG/FSH receptor, IPR002172:Low-density lipoprotein (LDL) receptor class A repeat, IPR003591:Leucine-rich repeat, typical subtype" CG34411 27-Aug-18 DroID_v2018_08 "Drer\fshr, Drer\lhcgr, Drer\tshr, Drer\rxfp1, Drer\lgr4, Drer\rxfp2b, Drer\rxfp2a, Drer\rxfp2l" - "Cele\fshr-1, Cele\sma-10" "Xtro\rxfp2, Xtro\fshr, Xtro\tshr, Xtro\rxfp1" "Mmus\Rxfp2, Mmus\Flrt2, Mmus\Lgr4, Mmus\Lhcgr, Mmus\Lgr5, Mmus\Lrfn5, Mmus\Tshr, Mmus\Rxfp1, Mmus\Fshr, Mmus\Lgr6" "Hsap\LHCGR, Hsap\LGR5, Hsap\FLRT2, Hsap\RXFP1, Hsap\LGR4, Hsap\LGR6, Hsap\TSHR, Hsap\RXFP2, Hsap\LRFN5, Hsap\FSHR" FBgn0010191 tu-So tu-So http://flybase.org/reports/FBgn0010191 - gene - - - "tu-So[c], tu-So" - - 27-Aug-18 DroID_v2018_08 - - - - - - partially lethal - majority die FBgn0041102 ocn ocnus http://flybase.org/reports/FBgn0041102 protein_coding_gene phosphohistidine phosphatase activity ; GO:0008969 | inferred from biological aspect of ancestor with PANTHER:PTN000262360 peptidyl-histidine dephosphorylation ; GO:0035971 | inferred from biological aspect of ancestor with PANTHER:PTN000262360 nucleus ; GO:0005634 | inferred from direct assay cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000262360 "CG7929, bs29e10.y1, BcDNA:GH02250, ocn, Ocn" IPR007702:Janus CG7929 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-51e6.1, Drer\phpt1" - Cele\phip-1 Xtro\phpt1 Mmus\Phpt1 Hsap\PHPT1 viable FBgn0001383 l(1)2Bo lethal (1) 2Bo http://flybase.org/reports/FBgn0001383 - gene - - - l(1)2Bo - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0037898 Dtd - http://flybase.org/reports/FBgn0037898 protein_coding_gene aminoacyl-tRNA editing activity ; GO:0002161 | inferred from biological aspect of ancestor with PANTHER:PTN000049487 D-tyrosyl-tRNA(Tyr) deacylase activity ; GO:0051500 | inferred from biological aspect of ancestor with PANTHER:PTN000049487 tRNA metabolic process ; GO:0006399 | inferred from biological aspect of ancestor with PANTHER:PTN000049487 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000049487 CG18643 "IPR023509:D-Tyr tRNAtyr deacylase-like domain, IPR003732:D-aminoacyl-tRNA deacylase DTD" CG18643 27-Aug-18 DroID_v2018_08 "Drer\dtd2, Drer\dtd1, Drer\gcc1" Scer\DTD1 Cele\pqn-68 "Xtro\dtd2, Xtro\gcc1, Xtro\dtd1" "Mmus\Gcc1, Mmus\Dtd1, Mmus\Dtd2" "Hsap\DTD1, Hsap\GCC1, Hsap\DTD2" DRSC15362 K -0.244006956 0.259801922 0.215989131 0.328945131 0.227800281 1.566617609 FBgn0024342 KH2-9 KH domain cDNA KH2-9 http://flybase.org/reports/FBgn0024342 - gene - - - KH2-9 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035888 CG7120 - http://flybase.org/reports/FBgn0035888 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR017849, InterPro:IPR017850" "metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR017849, InterPro:IPR017850" - "BcDNA:AT15424, CG7120, gi7295100" "IPR004245:Protein of unknown function DUF229, IPR017850:Alkaline-phosphatase-like, core domain, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha" CG7120 27-Aug-18 DroID_v2018_08 - - "Cele\F32G8.2, Cele\T07G12.3, Cele\Y73F8A.35, Cele\T23E1.1, Cele\Y41E3.1, Cele\R03G8.1, Cele\F32D8.2, Cele\Y38A10A.2, Cele\M03F8.5, Cele\F15H10.7, Cele\F10C2.3, Cele\F07C3.3, Cele\R03G8.3, Cele\K03A11.4" - - - "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0024883 l(2)04548 lethal (2) 04548 http://flybase.org/reports/FBgn0024883 - gene - - - l(2)04548 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0013618 l(3)L5150 lethal (3) L5150 http://flybase.org/reports/FBgn0013618 - gene - - - l(3)L5150 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0037427 Osi17 Osiris 17 http://flybase.org/reports/FBgn0037427 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of plasma membrane ; GO:0005887 | inferred from sequence model "CG15598, Osi17, mdcds_43703" IPR012464:Protein of unknown function DUF1676 CG15598 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,some die during pupal stage" FBgn0003707 TipB Temperature-induced paralytic B http://flybase.org/reports/FBgn0003707 - gene - - - TipB - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,paralytic,heat sensitive" FBgn0020523 nerd nerd http://flybase.org/reports/FBgn0020523 - gene molecular_function ; GO:0003674 | no biological data available mating behavior ; GO:0007617 | inferred from mutant phenotype pheromone biosynthetic process ; GO:0042811 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "Nerd, nerd" - - 27-Aug-18 DroID_v2018_08 - - - - - - "mating defective,male,recessive" FBgn0013582 l(3)82Fj lethal (3) 82Fj http://flybase.org/reports/FBgn0013582 - gene - - - l(3)82Fj - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0062620 Mod(var)1181 Mod(var)1181 http://flybase.org/reports/FBgn0062620 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1181, Mod(var)1181" - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,reduced,suppressor of variegation,recessive,dominant,non-enhancer of variegation,non-suppressor of variegation" FBgn0035227 Iml1 Increased minichromosome loss 1 http://flybase.org/reports/FBgn0035227 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with SGD:S000003899 GTPase activator activity ; GO:0005096 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000323637 negative regulation of TORC1 signaling ; GO:1904262 | inferred from mutant phenotype cellular response to amino acid starvation ; GO:0034198 | inferred from biological aspect of ancestor with PANTHER:PTN000323637 regulation of TORC1 signaling ; GO:1903432 | inferred from mutant phenotype negative regulation of TOR signaling ; GO:0032007 | inferred from biological aspect of ancestor with PANTHER:PTN000323637 regulation of autophagy ; GO:0010506 | inferred from biological aspect of ancestor with PANTHER:PTN000323637 cellular response to amino acid starvation ; GO:0034198 | inferred from mutant phenotype negative regulation of TOR signaling ; GO:0032007 | inferred from mutant phenotype negative regulation of cell size ; GO:0045792 | inferred from mutant phenotype germarium-derived cystoblast division ; GO:0048142 | inferred from mutant phenotype Seh1-associated complex ; GO:0035859 | inferred from direct assay lysosomal membrane ; GO:0005765 | inferred from biological aspect of ancestor with PANTHER:PTN000995343 Iml1 complex ; GO:1990130 | traceable author statement Seh1-associated complex ; GO:0035859 | inferred from sequence or structural similarity with SGD:S000003899 "Iml1, CG12090, iml1, SEA1" IPR027244:Vacuolar membrane-associated protein Iml1 CG12090 27-Aug-18 DroID_v2018_08 Drer\depdc5 Scer\IML1 Cele\T08A11.1 Xtro\depdc5 Mmus\Depdc5 Hsap\DEPDC5 "viable,fertile" FBgn0065535 l(2)SH1089 lethal (2) SH1089 http://flybase.org/reports/FBgn0065535 gene - - - "l(2)SH1089, l(2)SH2 1089" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0045060 fs(1)137a female sterile (1) 137a http://flybase.org/reports/FBgn0045060 gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(1)137a - - 27-Aug-18 DroID_v2018_08 - - - - - - female sterile "germarium,ovary" FBgn0020592 anon-57Ce anon-57Ce http://flybase.org/reports/FBgn0020592 - gene - - - anon-57Ce - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001145 Gs2 Glutamine synthetase 2 http://flybase.org/reports/FBgn0001145 - protein_coding_gene glutamate-ammonia ligase activity ; GO:0004356 | inferred from direct assay glutamate-ammonia ligase activity ; GO:0004356 | non-traceable author statement glutamine biosynthetic process ; GO:0006542 | inferred from electronic annotation with InterPro:IPR008147 glutamine biosynthetic process ; GO:0006542 | non-traceable author statement glutamate catabolic process ; GO:0006538 | inferred from mutant phenotype synapse assembly ; GO:0007416 | inferred from mutant phenotype neurotransmitter receptor metabolic process ; GO:0045213 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:4341 "gs2, CG1743, GS2, gs-c, GsII, Gs2" "IPR008146:Glutamine synthetase, catalytic domain, IPR008147:Glutamine synthetase, beta-Grasp domain, IPR014746:Glutamine synthetase/guanido kinase, catalytic domain, IPR027302:Glutamine synthetase, N-terminal conserved site, IPR027303:Glutamine synthetase, glycine-rich site" CG1743 27-Aug-18 DroID_v2018_08 "Drer\glulb, Drer\glulc, Drer\glula, Drer\lgsn" Scer\GLN1 "Cele\gln-1, Cele\gln-5, Cele\gln-6, Cele\gln-2, Cele\gln-3" "Xtro\glul, Xtro\lgsn" "Mmus\Glul, Mmus\Lgsn" "Hsap\GLUL, Hsap\LGSN" " adult stage , larval stage | first instar , larval stage | second instar " "neurophysiology defective,viable" FBgn0016701 Rab4 Rab4 http://flybase.org/reports/FBgn0016701 - protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579, InterPro:IPR005225 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11 protein binding ; GO:0005515 | inferred from physical interaction with Vps52 inferred from physical interaction with CG31064" Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 ovarian follicle cell-cell adhesion ; GO:0007299 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 regulation of endocytosis ; GO:0030100 | inferred from biological aspect of ancestor with PANTHER:PTN001530980 endocytosis ; GO:0006897 | traceable author statement plasma membrane ; GO:0005886 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay synapse ; GO:0045202 | inferred from direct assay endosome ; GO:0005768 | inferred from direct assay vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 recycling endosome ; GO:0055037 | inferred from direct assay "CG4921, DmRab4, DRAB4, Rab4, rab4, CG 4921, RAB4c, Q7KY04" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG4921 27-Aug-18 DroID_v2018_08 "Drer\rab14, Drer\rab2a, Drer\rab14l, Drer\rab4a, Drer\rab4b" "Scer\YPT32, Scer\YPT31" Cele\unc-108 "Xtro\rab14, Xtro\rab2b, Xtro\rab4b, Xtro\rab2a" "Mmus\Rab4a, Mmus\Mia, Mmus\Rab14, Mmus\Rab4b, Mmus\Rab2a" "Hsap\RAB2A, Hsap\MIA, Hsap\RAB14, Hsap\EGLN2, Hsap\RAB4A, Hsap\RAB2B, Hsap\RAB4B" "viable,neuroanatomy defective" embryonic/larval glial cell FBgn0037501 Ir84a Ionotropic receptor 84a http://flybase.org/reports/FBgn0037501 protein_coding_gene "ionotropic glutamate receptor activity ; GO:0004970 | inferred from electronic annotation with InterPro:IPR001320, InterPro:IPR019594 extracellular-glutamate-gated ion channel activity ; GO:0005234 | inferred from electronic annotation with InterPro:IPR019594 extracellular phenylacetaldehyde-gated ion channel activity ; GO:0036082 | contributes_to inferred from direct assay co-receptor binding ; GO:0039706 | inferred from physical interaction with Ir8a olfactory receptor activity ; GO:0004984 | contributes_to inferred from direct assay extracellular phenylacetaldehyde-gated ion channel activity ; GO:0036082 | inferred from direct assay" detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from mutant phenotype detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from direct assay male courtship behavior ; GO:0008049 | inferred from mutant phenotype transmission of nerve impulse ; GO:0019226 | inferred from mutant phenotype receptor complex ; GO:0043235 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model dendrite terminus ; GO:0044292 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay sensory dendrite ; GO:0071683 | inferred from direct assay "Ir84a, CT28433, IR84a, CG10101, DmelIR84a" "IPR019594:Ionotropic glutamate receptor, L-glutamate and glycine-binding domain" CG10101 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-251b21.1, Drer\si:dkey-183j2.10, Drer\grik1b, Drer\grik1a, Drer\grik4" - "Cele\glr-4, Cele\glr-5, Cele\glr-8" - "Mmus\Grik4, Mmus\Grik1" "Hsap\GRIK1, Hsap\GRIK4" "smell perception defective,recessive,neurophysiology defective,courtship behavior defective,male limited,viable,visible,body color defective" "trichogen cell,mesothoracic tergum,sensillum coeloconicum of antennal segment 3" FBgn0061139 l(3)S000627b lethal (3) S000627b http://flybase.org/reports/FBgn0061139 gene - - - "0006/27, l(3)S000627b" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0005531 l(2)52ACh lethal (2) 52ACh http://flybase.org/reports/FBgn0005531 - gene - - - l(2)52ACh - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0016805 l(1)K7 lethal (1) K7 http://flybase.org/reports/FBgn0016805 - gene - - - "l(1)K7, K7" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0065652 l(2)SH0732 lethal (2) SH0732 http://flybase.org/reports/FBgn0065652 gene - - - "l(2)SH0732, l(2)SH2 0732" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0030800 Nprl2 Nitrogen permease regulator-like 2 http://flybase.org/reports/FBgn0030800 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Nprl3 negative regulation of TOR signaling ; GO:0032007 | inferred from mutant phenotype negative regulation of cell size ; GO:0045792 | inferred from mutant phenotype negative regulation of TORC1 signaling ; GO:1904262 | inferred from mutant phenotype TORC1 signaling ; GO:0038202 | inferred from mutant phenotype cellular response to nitrogen starvation ; GO:0006995 | inferred from biological aspect of ancestor with PANTHER:PTN000988255 dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype cellular response to amino acid starvation ; GO:0034198 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | inferred from genetic interaction with mio inferred from genetic interaction with Nup44A positive regulation of autophagy ; GO:0010508 | inferred from biological aspect of ancestor with PANTHER:PTN000988255 oogenesis ; GO:0048477 | inferred from mutant phenotype negative regulation of TORC1 signaling ; GO:1904262 | inferred from genetic interaction with Wdr24 regulation of autophagosome assembly ; GO:2000785 | inferred from biological aspect of ancestor with PANTHER:PTN000988255 autolysosome ; GO:0044754 | inferred from direct assay Seh1-associated complex ; GO:0035859 | inferred from sequence or structural similarity with SGD:S000000788 cytoplasm ; GO:0005737 | inferred from direct assay Iml1 complex ; GO:1990130 | traceable author statement Seh1-associated complex ; GO:0035859 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG9104, nprl2, npr2, Nprl2, NPR2, Nplr2" IPR009348:Nitrogen permease regulator 2 CG9104 27-Aug-18 DroID_v2018_08 "Drer\zmynd10, Drer\nprl2" Scer\NPR2 Cele\nprl-2 "Xtro\nprl2, Xtro\zmynd10" Mmus\Nprl2 "Hsap\NPRL2, Hsap\ZMYND10" viable FBgn0038173 Adgf-C Adenosine deaminase-related growth factor C http://flybase.org/reports/FBgn0038173 protein_coding_gene "growth factor activity ; GO:0008083 | inferred from sequence or structural similarity with Adgf-A, Adgf-D adenosine deaminase activity ; GO:0004000 | inferred from sequence or structural similarity with Adgf-A, Adgf-D" "cell proliferation ; GO:0008283 | inferred from sequence or structural similarity with Adgf-A, Adgf-D adenosine catabolic process ; GO:0006154 | inferred from sequence or structural similarity with Adgf-A, Adgf-D" "extracellular space ; GO:0005615 | inferred from electronic annotation with InterPro:IPR006331, InterPro:IPR013659 extracellular space ; GO:0005615 | inferred from sequence model" "ADGF-C, CG9345, adgfc, Adgf-C, AdgfC" "IPR001365:Adenosine/AMP deaminase domain, IPR006331:Adenosine deaminase-related growth factor, IPR013659:Adenosine/AMP deaminase N-terminal, IPR032466:Metal-dependent hydrolase" CG9345 27-Aug-18 DroID_v2018_08 "Drer\cecr1a, Drer\ada, Drer\adal, Drer\cecr1b" Scer\AAH1 Cele\C44B7.12 "Xtro\ada.2, Xtro\ada, Xtro\adal, Xtro\cecr1" "Mmus\Ada, Mmus\Adal" "Hsap\ADA, Hsap\ADAL, Hsap\CECR1" viable FBgn0003114 plu plutonium http://flybase.org/reports/FBgn0003114 FBgn0034492 protein_coding_gene - negative regulation of DNA replication ; GO:0008156 | inferred from mutant phenotype regulation of mitotic cell cycle ; GO:0007346 | traceable author statement egg activation ; GO:0007343 | inferred from mutant phenotype single fertilization ; GO:0007338 | inferred from mutant phenotype serine/threonine protein kinase complex ; GO:1902554 | inferred from physical interaction with png "Plu, PLU, CG9183, plu" "IPR002110:Ankyrin repeat, IPR020683:Ankyrin repeat-containing domain" CG9183 27-Aug-18 DroID_v2018_08 - - Cele\C01F1.6 - - Hsap\POTEA embryonic stage | 0-6 hr "lethal,maternal effect,viable,fertile,lethal - all die before end of embryonic stage,some die during embryonic stage,wild-type,female sterile,meiotic cell cycle defective" "nucleus | embryonic stage,oocyte nucleus,nuclear chromosome,male pronucleus,female pronucleus,polar body nucleus,pronucleus" FBgn0040717 Nplp4 Neuropeptide-like precursor 4 http://flybase.org/reports/FBgn0040717 protein_coding_gene neuropeptide hormone activity ; GO:0005184 | non-traceable author statement neuropeptide signaling pathway ; GO:0007218 | non-traceable author statement extracellular region ; GO:0005576 | non-traceable author statement "NPLP4, CG15361, Nplp4, YSY" - CG15361 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC00391 K 0.125492502 0.573520674 0.99485833 0.041946835 0.886170861 1.982170871 FBgn0266443 CG45073 - http://flybase.org/reports/FBgn0266443 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG45073, CG18682" IPR006631:Protein of unknown function DM4/12 CG45073 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039108 CG10232 - http://flybase.org/reports/FBgn0039108 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP14, CG10232" "IPR001314:Peptidase S1A, chymotrypsin family, IPR001254:Serine proteases, trypsin domain, IPR018114:Serine proteases, trypsin family, histidine active site, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG10232 27-Aug-18 DroID_v2018_08 Drer\masp2 - "Cele\try-3, Cele\try-1" - Mmus\Klk1b5 - viable FBgn0035087 CG2765 - http://flybase.org/reports/FBgn0035087 protein_coding_gene myosin binding ; GO:0017022 | inferred from physical interaction with Myo10A - - CG2765 IPR009786:Spot 14 family CG2765 27-Aug-18 DroID_v2018_08 "Drer\thrsp, Drer\mid1ip1l, Drer\mid1ip1b, Drer\mid1ip1a" - - "Xtro\mid1ip1, Xtro\thrsp" "Mmus\Mid1ip1, Mmus\Thrsp" "Hsap\MID1IP1, Hsap\THRSP" viable FBgn0053558 mim missing-in-metastasis http://flybase.org/reports/FBgn0053558 protein_coding_gene actin binding ; GO:0003779 | inferred from electronic annotation with InterPro:IPR030127 phospholipid binding ; GO:0005543 | inferred from direct assay SH3 domain binding ; GO:0017124 | inferred from direct assay protein homodimerization activity ; GO:0042803 | inferred from physical interaction with mim plasma membrane organization ; GO:0007009 | inferred from electronic annotation with InterPro:IPR013606 filopodium assembly ; GO:0046847 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype germ cell migration ; GO:0008354 | inferred from mutant phenotype negative regulation of receptor-mediated endocytosis ; GO:0048261 | inferred from mutant phenotype protein complex ; GO:0043234 | inferred from physical interaction with Cortactin "CG9469, anon-EST:fe1E4, CG33352, mim, CG33558, dmim, MIM, Dm_2R:10851, Mim" "IPR013606:IMD/I-BAR domain, IPR030127:I-BAR domain containing protein MIM/ABBA, IPR027267:Arfaptin homology (AH) domain/BAR domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR011990:Tetratricopeptide-like helical domain, IPR011989:Armadillo-like helical" CG33558 27-Aug-18 DroID_v2018_08 "Drer\mtss1l, Drer\mtss1, Drer\mtss1la" - Cele\M04F3.5 "Xtro\mtss1.1, Xtro\mtss1l, Xtro\mtss1.2" "Mmus\Mtss1, Mmus\Mtss1l" "Hsap\MTSS1L, Hsap\MTSS1" "female sterile,partially,locomotor behavior defective,viable" "border follicle cell,germline cell" FBgn0020391 Nrk Neurospecific receptor kinase http://flybase.org/reports/FBgn0020391 "FBgn0021861, FBgn0022790, FBgn0082206" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR016247, InterPro:IPR017441 protein tyrosine kinase activity ; GO:0004713 | non-traceable author statement protein tyrosine kinase activity ; GO:0004713 | inferred from direct assay transmembrane receptor protein tyrosine kinase activity ; GO:0004714 | inferred from sequence or structural similarity" transmembrane receptor protein tyrosine kinase signaling pathway ; GO:0007169 | inferred from electronic annotation with InterPro:IPR016247 protein phosphorylation ; GO:0006468 | inferred from direct assay protein phosphorylation ; GO:0006468 | non-traceable author statement muscle cell cellular homeostasis ; GO:0046716 | inferred from mutant phenotype inferred from genetic interaction with Dg inferred from genetic interaction with Dys signal transduction ; GO:0007165 | inferred from direct assay rhabdomere development ; GO:0042052 | inferred from mutant phenotype photoreceptor cell axon guidance ; GO:0072499 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from sequence or structural similarity "CG4007, DmHD-434, Dnrk, nrtk_dros, DNRK, l(2)k14301, HD-434, anon-WO2004063362.79, Nrk, ROR2, nrk" "IPR018056:Kringle, conserved site, IPR000001:Kringle, IPR000719:Protein kinase domain, IPR008266:Tyrosine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR013806:Kringle-like fold, IPR016247:Tyrosine-protein kinase, receptor ROR, IPR017441:Protein kinase, ATP binding site, IPR020067:Frizzled domain, IPR020635:Tyrosine-protein kinase, catalytic domain, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain" CG4007 27-Aug-18 DroID_v2018_08 Drer\musk - Cele\cam-1 "Xtro\ror2, Xtro\ror1, Xtro\musk" "Mmus\Ror2, Mmus\Hgf, Mmus\Kremen2, Mmus\Musk, Mmus\Plat, Mmus\F2, Mmus\Hgfac" "Hsap\PLG, Hsap\PLAT, Hsap\ROR1, Hsap\HGF, Hsap\HABP2, Hsap\MUSK, Hsap\KREMEN2, Hsap\HGFAC" " embryonic stage -- adult stage , embryonic stage | stage >=10 , embryonic stage | stage 17 " " neurogenic region

, embryonic central nervous system

, peripheral nervous system

" "lethal,recessive,viable" FBgn0033614 Obp47b Odorant-binding protein 47b http://flybase.org/reports/FBgn0033614 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 extracellular region ; GO:0005576 | inferred from sequence model "CG13208, Obp47b, DmelObp47b" IPR006170:Pheromone/general odorant binding protein CG13208 27-Aug-18 DroID_v2018_08 - - - - Mmus\Actn4 Hsap\ACTN4 DRSC27574 K -0.569382885 0.036594396 -0.141242658 0.545977019 -1.751191302 -1.209422814 FBgn0028416 Met75Ca Met75Ca http://flybase.org/reports/FBgn0028416 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "CG32197, Met75Ca" - CG32197 27-Aug-18 DroID_v2018_08 - - - - - - DRSC09549 IE 1.588241685 1.251812384 1.544626368 -0.566911988 -0.583411236 -1.042212316 FBgn0036462 mRpL39 mitochondrial ribosomal protein L39 http://flybase.org/reports/FBgn0036462 protein_coding_gene nucleotide binding ; GO:0000166 | inferred from electronic annotation with InterPro:IPR018163 structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with EMBL:AL353983 mitochondrial translation ; GO:0032543 | traceable author statement translation ; GO:0006412 | inferred from sequence or structural similarity with EMBL:AL353983 mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with EMBL:AL353983 mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with UniProtKB:Q9NYK5 "mRpL5, MRP-L5, CG17166, mRpL39" "IPR018163:Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain, IPR012675:Beta-grasp domain" CG17166 27-Aug-18 DroID_v2018_08 "Drer\tars2, Drer\cenpq, Drer\rprd2b, Drer\tars" "Scer\THS1, Scer\MST1, Scer\AIM10" "Cele\tars-1, Cele\mrpl-39" "Xtro\mrpl39, Xtro\tars, Xtro\tarsl2" "Mmus\Mrpl39, Mmus\Tarsl2, Mmus\Tars, Mmus\Tars2" "Hsap\TARS2, Hsap\MRPL39, Hsap\TARS, Hsap\TARSL2" "viable,visible" trichogen cell FBgn0002319 l(3)85Ec lethal (3) 85Ec http://flybase.org/reports/FBgn0002319 - gene - - - "l(3)WG89, l(3)SG39, l(3)85Ec" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of prepupal stage,some die during prepupal stage,recessive" FBgn0264832 CG44040 - http://flybase.org/reports/FBgn0264832 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44040 - CG44040 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065356 l(2)SH1760 lethal (2) SH1760 http://flybase.org/reports/FBgn0065356 gene - - - "l(2)SH1760, l(2)SH2 1760" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0052446 Atox1 Antioxidant 1 copper chaperone http://flybase.org/reports/FBgn0052446 protein_coding_gene copper chaperone activity ; GO:0016531 | inferred from biological aspect of ancestor with PANTHER:PTN001106576 intracellular copper ion transport ; GO:0015680 | inferred from biological aspect of ancestor with PANTHER:PTN001106576 cellular copper ion homeostasis ; GO:0006878 | inferred from biological aspect of ancestor with PANTHER:PTN001106576 response to oxidative stress ; GO:0006979 | inferred from biological aspect of ancestor with PANTHER:PTN001106576 copper ion homeostasis ; GO:0055070 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000517250 "CG12562, Atox1, CG32446, DmAtox1" "IPR006121:Heavy metal-associated domain, HMA" CG32446 27-Aug-18 DroID_v2018_08 Drer\atox1 Scer\ATX1 Cele\cuc-1 Xtro\atox1 Mmus\Atox1 Hsap\ATOX1 "wild-type,partially lethal - majority die,fertile,lethal,chemical conditional,viable" FBgn0060633 l(3)S085203 lethal (3) S085203 http://flybase.org/reports/FBgn0060633 gene - - - "0852/03, l(3)S085203" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0016858 l(1)N5 lethal (1) N5 http://flybase.org/reports/FBgn0016858 - gene - - - "l(1)N5, N5" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0027211 l(1)G0355 lethal (1) G0355 http://flybase.org/reports/FBgn0027211 - gene - - - l(1)G0355 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,partially lethal - majority die,recessive" FBgn0011535 l(3)00945 lethal (3) 00945 http://flybase.org/reports/FBgn0011535 - gene - - - l(3)00945 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0028121 l(3)S059706 lethal (3) S059706 http://flybase.org/reports/FBgn0028121 gene - - - l(3)S059706 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0052359 tRNA:Leu-CAG-1-3 transfer RNA:Leucine-CAG 1-3 http://flybase.org/reports/FBgn0052359 tRNA_gene CUG codon-amino acid adaptor activity ; GO:0033420 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033420 cytosol ; GO:0005829 | inferred by curator from GO:0033420 "AE002602.trna9-LeuCAG, tRNA:L:CAG:AE002602-e, CR32359, chr3L.trna43-LeuCAG, tRNA-Leu-CAG-1-3, tRNA:Leu-CAG-1-3, tRNA:CR32359, CUG" - CR32359 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0011212 bet betel http://flybase.org/reports/FBgn0011212 - gene - spermatid development ; GO:0007286 | inferred from mutant phenotype - "ms(3)04066, bet" - - 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,recessive" FBgn0032746 CG10470 - http://flybase.org/reports/FBgn0032746 protein_coding_gene calcium channel activity ; GO:0005262 | inferred from electronic annotation with InterPro:IPR008559 endoplasmic reticulum calcium ion homeostasis ; GO:0032469 | inferred from electronic annotation with InterPro:IPR008559 integral component of endoplasmic reticulum membrane ; GO:0030176 | inferred from electronic annotation with InterPro:IPR008559 "TuB2, TUB2, TU37B2, B2, anon-37B-2, CG10470" "IPR008559:Calcium load-activated calcium channel, IPR002809:Integral membrane protein EMC3/TMCO1-like" CG10470 27-Aug-18 DroID_v2018_08 Drer\tmco1 - Cele\F22B5.10 Xtro\tmco1 Mmus\Tmco1 Hsap\TMCO1 viable FBgn0266568 lncRNA:yar yellow-achaete intergenic RNA http://flybase.org/reports/FBgn0266568 non_protein_coding_gene - "regulation of circadian sleep/wake cycle, sleep ; GO:0045187 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay "yar, CR42744, anon-1Be" - CR42744 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0029996 UbcE2H Ubiquitin conjugating enzyme E2H http://flybase.org/reports/FBgn0029996 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:12484 ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from biological aspect of ancestor with PANTHER:PTN000630520 lateral inhibition ; GO:0046331 | inferred from mutant phenotype protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with HGNC:12484 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 "dUbc-E2H, CG2257, UbcE2H, Ubc-E2H, Ubc-E2Hs, ubcE2h, UbcDE2H" "IPR000608:Ubiquitin-conjugating enzyme E2, IPR016135:Ubiquitin-conjugating enzyme/RWD-like, IPR023313:Ubiquitin-conjugating enzyme, active site" CG2257 27-Aug-18 DroID_v2018_08 Drer\ube2h Scer\UBC8 Cele\ubc-8 Xtro\ube2h Mmus\Ube2h Hsap\UBE2H "lethal,recessive,viable,visible,body color defective,stress response defective" "chaeta,supernumerary,mesothoracic tergum" DRSC18221 K 1.108765544 -1.432740002 -0.090545954 0.468259198 1.716623345 0.861211737 FBgn0086655 jing jing http://flybase.org/reports/FBgn0086655 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 "axon guidance ; GO:0007411 | inferred from mutant phenotype ventral midline development ; GO:0007418 | inferred from mutant phenotype open tracheal system development ; GO:0007424 | inferred from mutant phenotype imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype tissue regeneration ; GO:0042246 | inferred from mutant phenotype glial cell migration ; GO:0008347 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype specification of segmental identity, maxillary segment ; GO:0007382 | inferred from expression pattern inferred from genetic interaction with Dfd negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype central nervous system development ; GO:0007417 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype leg disc proximal/distal pattern formation ; GO:0007479 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype" ESC/E(Z) complex ; GO:0035098 | inferred from direct assay nucleus ; GO:0005634 | inferred from sequence or structural similarity with ci inferred from sequence or structural similarity with MGI:MGI:1338038 inferred from direct assay "1.28, jing, CT9093, CG9397, CG9403, l(2)01094, l(2)22F3, Jing, AEBP2" IPR013087:Zinc finger C2H2-type CG9397 27-Aug-18 DroID_v2018_08 Drer\aebp2 - - Xtro\aebp2 Mmus\Aebp2 Hsap\AEBP2 " embryonic stage | stage 10-16 , embryonic stage , embryonic stage | stage 9-15 , embryonic stage | stage 9 " " tracheal primordium

anterior , embryonic abdominal segment 8 | restricted

, proctodeum

, ventral midline

, ventral neurogenic region | segmentally repeated

, epidermis &&of embryonic maxillary segment

, embryonic/larval hindgut

, embryonic prothoracic segment | restricted

, anterior embryonic/larval midgut

, posterior embryonic/larval midgut

, supraesophageal ganglion

" " embryonic stage | stage 9-14 , embryonic stage | stage 10-16 " " ventral midline

, tracheal primordium

" FBgn0085497 CG40577 - http://flybase.org/reports/FBgn0085497 protein_coding_gene - - - CG40577 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260657 CG42540 - http://flybase.org/reports/FBgn0260657 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001972 "CG42540, CG13719, CG7468, CG13718, CG32245" "IPR018080:Band 7/stomatin-like, conserved site, IPR001107:Band 7 domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR001972:Stomatin family" CG42540 27-Aug-18 DroID_v2018_08 "Drer\stoml3a, Drer\zgc:112408, Drer\stoml3b, Drer\nphs2, Drer\stoml1, Drer\stom" - "Cele\mec-2, Cele\sto-4, Cele\sto-3, Cele\unc-1, Cele\sto-5, Cele\sto-6, Cele\sto-2, Cele\sto-1" "Xtro\stom, Xtro\stoml1, Xtro\stoml3" "Mmus\Stoml3, Mmus\Stom, Mmus\Nphs2, Mmus\Stoml1" "Hsap\STOML1, Hsap\STOML3, Hsap\STOM, Hsap\NPHS2" DRSC23011 K -0.571316278 2.483099691 FBgn0038584 mTerf5 mitochondrial transcription termination factor 5 http://flybase.org/reports/FBgn0038584 protein_coding_gene double-stranded DNA binding ; GO:0003690 | inferred from electronic annotation with InterPro:IPR003690 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR003690 transcription from mitochondrial promoter ; GO:0006390 | inferred from mutant phenotype" mitochondrion ; GO:0005739 | inferred from direct assay "mTerf5, D-MTERF5, CG7175" "IPR003690:Transcription termination factor, mitochondrial/chloroplastic" CG7175 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible" trichogen cell FBgn0031720 CG14013 - http://flybase.org/reports/FBgn0031720 protein_coding_gene - - - CG14013 IPR027887:Protein of unknown function DUF4464 CG14013 27-Aug-18 DroID_v2018_08 Drer\si:ch211-57h10.1 - - - Mmus\1700007G11Rik Hsap\C4orf22 "viable,body color defective" mesothoracic tergum FBgn0039655 CG14507 - http://flybase.org/reports/FBgn0039655 protein_coding_gene phospholipase A2 activity ; GO:0004623 | inferred from electronic annotation with InterPro:IPR001211 calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001211 "phospholipid metabolic process ; GO:0006644 | inferred from electronic annotation with InterPro:IPR016090 arachidonic acid secretion ; GO:0050482 | inferred from electronic annotation with InterPro:IPR016090 lipid catabolic process ; GO:0016042 | inferred from electronic annotation with InterPro:IPR001211, InterPro:IPR013090" - CG14507 "IPR001211:Phospholipase A2, IPR016090:Phospholipase A2 domain, IPR033112:Phospholipase A2, aspartic acid active site, IPR033113:Phospholipase A2, histidine active site" CG14507 27-Aug-18 DroID_v2018_08 "Drer\zgc:92162, Drer\oc90, Drer\pla2g1b" - "Cele\C03H5.4, Cele\C07E3.9, Cele\Y69A2AL.2" "Xtro\pla2g1b, Xtro\pla2g2e" "Mmus\Pla2g10, Mmus\Pla2g2c, Mmus\Pla2g5, Mmus\Oc90, Mmus\Pla2g2a, Mmus\Pla2g2d, Mmus\Pla2g1b, Mmus\Pla2g2e, Mmus\Pla2g2f" "Hsap\PLA2G5, Hsap\PLA2G1B, Hsap\OC90, Hsap\PLA2G2E, Hsap\PLA2G2D, Hsap\PLA2G2A, Hsap\PLA2G2C, Hsap\PLA2G10, Hsap\PLA2G2F" "viable,fertile" FBgn0033917 SmydA-1 "SET and MYND domain containing, arthropod-specific, member 1" http://flybase.org/reports/FBgn0033917 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from sequence model with Pfam:PF01753 histone deacetylase binding ; GO:0042826 | inferred from sequence or structural similarity with Smyd4-2 negative regulation of gene expression ; GO:0010629 | inferred from sequence or structural similarity with Smyd4-2 cytoplasm ; GO:0005737 | inferred from direct assay "SmydA-1, CG8503" "IPR002893:Zinc finger, MYND-type" CG8503 27-Aug-18 DroID_v2018_08 "Drer\smyd4, Drer\smyd1a, Drer\smyd2b, Drer\smyd3, Drer\smyd2a, Drer\smyd1b" "Scer\SET6, Scer\SET5" "Cele\set-30, Cele\set-18, Cele\set-10" "Xtro\smyd4, Xtro\smyd1, Xtro\smyd5" "Mmus\Smyd3, Mmus\Zmynd15, Mmus\Smyd1, Mmus\Smyd2, Mmus\Smyd4, Mmus\Smyd5" "Hsap\SMYD4, Hsap\SMYD2, Hsap\ZMYND15, Hsap\SMYD1, Hsap\SMYD5, Hsap\SMYD3" viable FBgn0266320 lncRNA:CR44985 - http://flybase.org/reports/FBgn0266320 non_protein_coding_gene - - - CR44985 - CR44985 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065216 l(2)SH2245 lethal (2) SH2245 http://flybase.org/reports/FBgn0065216 gene - - - "l(2)SH2245, l(2)SH2 2245" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0052670 Rab9Fb Rab at 9Fb http://flybase.org/reports/FBgn0052670 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579, InterPro:IPR005225 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11" vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 endocytic recycling ; GO:0032456 | inferred from biological aspect of ancestor with PANTHER:PTN001178320 vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN001178320 endosome membrane ; GO:0010008 | inferred from biological aspect of ancestor with PANTHER:PTN001178320 "DmRabX3, CG2532, Rab9Fb, CG32670, RabX3" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG32670 27-Aug-18 DroID_v2018_08 "Drer\rab1bb, Drer\rab19, Drer\rab33a, Drer\rab43, Drer\rab1ab, Drer\rab35b, Drer\si:dkey-16l2.16, Drer\rab35a, Drer\zgc:171927, Drer\rab1aa, Drer\rab33ba, Drer\rabl6a, Drer\rab1ba, Drer\rabl6b, Drer\zgc:101559" "Scer\TEM1, Scer\YPT1" "Cele\rab-35, Cele\rab-28" "Xtro\rab19, Xtro\rab33b, Xtro\rabl6, Xtro\rab28, Xtro\rab1a, Xtro\rab33a" "Mmus\Rab33a, Mmus\Rab35, Mmus\Rab33b, Mmus\Rab43, Mmus\Rab1a, Mmus\Rab19, Mmus\Rab28, Mmus\Rab1b, Mmus\Rabl6" "Hsap\RAB33B, Hsap\RAB33A, Hsap\RAB1A, Hsap\RAB43, Hsap\RAB1B, Hsap\RAB28, Hsap\RABL6, Hsap\RAB35, Hsap\RAB19" FBgn0267022 asRNA:CR45466 - http://flybase.org/reports/FBgn0267022 non_protein_coding_gene - - - CR45466 - CR45466 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051477 ATPsynepsilonL "ATP synthase, epsilon subunit-like" http://flybase.org/reports/FBgn0051477 protein_coding_gene "proton-transporting ATP synthase activity, rotational mechanism ; GO:0046933 | contributes_to inferred from sequence or structural similarity with SGD:S000006192 ATPase activity ; GO:0016887 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000278562" proton transport ; GO:0015992 | inferred from sequence or structural similarity with UniProtKB:P56381 ATP synthesis coupled proton transport ; GO:0015986 | inferred from sequence or structural similarity with SGD:S000006192 "mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) ; GO:0000275 | inferred from sequence or structural similarity with UniProtKB:P56381 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000278562" "CG12810, CG31477, ATPE, ATPsynepsilonL" "IPR006721:ATP synthase, F1 complex, epsilon subunit, mitochondrial" CG31477 27-Aug-18 DroID_v2018_08 Drer\atp5e Scer\ATP15 "Cele\R05D3.6, Cele\ZC262.5, Cele\hpo-18" - Mmus\Atp5e Hsap\ATP5E "viable,visible" trichogen cell DRSC14548 I 0.814122734 -2.043220409 -0.492273682 -1.105919192 0.666402913 1.466715498 FBgn0002495 l(3)SG55 lethal (3) SG55 http://flybase.org/reports/FBgn0002495 - gene - - - "l(3)L36, l(3)SG55" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0038775 CG17199 - http://flybase.org/reports/FBgn0038775 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR003767 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR003767 - CG17199 IPR003767:Malate/L-lactate dehydrogenase CG17199 27-Aug-18 DroID_v2018_08 - - "Cele\VF13D12L.3, Cele\F36A2.3" - - - viable FBgn0000923 fs(1)ne10 female sterile (1) no eggs 10 http://flybase.org/reports/FBgn0000923 - gene - - - "ne10, fs(1)ne[10], fs(1)ne10" - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive" "dorsal appendage,chorion,endochorion,oocyte" FBgn0005724 l(1)TK134 lethal (1) TK134 http://flybase.org/reports/FBgn0005724 - gene - - - "l134, l(1)TK134" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0260369 GSd205 - http://flybase.org/reports/FBgn0260369 gene - - - GSd205 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0031412 CG16995 - http://flybase.org/reports/FBgn0031412 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR018244 extracellular region ; GO:0005576 | inferred from sequence model CG16995 "IPR001283:Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR018244:Allergen V5/Tpx-1-related, conserved site, IPR014044:CAP domain, IPR034113:Golgi-associated plant pathogenesis-related protein 1, SCP domain" CG16995 27-Aug-18 DroID_v2018_08 "Drer\crispld2, Drer\r3hdml, Drer\pi15a, Drer\glipr2l, Drer\im:7150988, Drer\pi15b, Drer\LOC100536500, Drer\glipr2, Drer\crispld1b, Drer\crispld1a, Drer\glipr1b, Drer\LOC101883528" "Scer\PRY2, Scer\PRY3, Scer\PRY1" "Cele\C07A4.3, Cele\vap-2, Cele\scl-1, Cele\F57B7.2, Cele\F09B9.5, Cele\D2062.1, Cele\scl-19" "Xtro\crispld2, Xtro\crisp3, Xtro\glipr2, Xtro\crisp2, Xtro\crisp1, Xtro\r3hdml, Xtro\MGC108118" "Mmus\Crispld1, Mmus\Glipr1, Mmus\Glipr1l2, Mmus\Crispld2, Mmus\Crisp2, Mmus\Crisp4, Mmus\Pi16, Mmus\R3hdml, Mmus\Pi15, Mmus\Crisp3, Mmus\Glipr2, Mmus\Glipr1l1, Mmus\Clec18a, Mmus\Crisp1" "Hsap\GLIPR1L2, Hsap\GLIPR1, Hsap\PI16, Hsap\CLEC18A, Hsap\CLEC18B, Hsap\R3HDML, Hsap\CRISPLD1, Hsap\CLEC18C, Hsap\CRISP1, Hsap\GLIPR2, Hsap\CRISPLD2, Hsap\GLIPR1L1, Hsap\PI15, Hsap\CRISP2" viable FBgn0266352 asRNA:CR45001 - http://flybase.org/reports/FBgn0266352 non_protein_coding_gene - - - CR45001 - CR45001 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085574 CG41248 - http://flybase.org/reports/FBgn0085574 protein_coding_gene - - - CG41248 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060472 l(3)S112014 lethal (3) S112014 http://flybase.org/reports/FBgn0060472 gene - - - "1120/14, l(3)S112014" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0261267 CG42615 - http://flybase.org/reports/FBgn0261267 protein_coding_gene - - - "CG42615, gft" - CG42615 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060869 l(3)S047208 lethal (3) S047208 http://flybase.org/reports/FBgn0060869 gene - - - "0472/08, l(3)S047208" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0267546 asRNA:CR45886 - http://flybase.org/reports/FBgn0267546 non_protein_coding_gene - - - "CR45886, Mgn1717" - CR45886 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0086368 tw twisted http://flybase.org/reports/FBgn0086368 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VTK2 dolichyl-phosphate-mannose-protein mannosyltransferase activity ; GO:0004169 | contributes_to inferred from direct assay dolichyl-phosphate-mannose-protein mannosyltransferase activity ; GO:0004169 | inferred from direct assay muscle organ development ; GO:0007517 | inferred from mutant phenotype somatic muscle development ; GO:0007525 | inferred from mutant phenotype ER-associated misfolded protein catabolic process ; GO:0071712 | inferred from biological aspect of ancestor with PANTHER:PTN000006098 sarcomere organization ; GO:0045214 | inferred from genetic interaction with Dg muscle attachment ; GO:0016203 | inferred from genetic interaction with Dg lipid glycosylation ; GO:0030259 | inferred from mutant phenotype protein O-linked mannosylation ; GO:0035269 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN000006098 endoplasmic reticulum ; GO:0005783 | inferred from direct assay "Pomt2, tw, CG12311, POMT2, DPOMT2, dPOMT2, EG:34F3.7, DmPOMT2, dPomt2, Tw" "IPR003342:Glycosyl transferase family 39/83, IPR016093:MIR motif, IPR027005:Glycosyltransferase 39-like, IPR032421:Protein O-mannosyl-transferase, C-terminal four TM domain" CG12311 27-Aug-18 DroID_v2018_08 "Drer\sdf2l1, Drer\pomt1, Drer\pomt2" "Scer\PMT5, Scer\PMT4, Scer\PMT6, Scer\PMT2, Scer\PMT7, Scer\PMT3, Scer\PMT1" Cele\R12E2.13 "Xtro\pomt2, Xtro\pomt1" "Mmus\Sdf2l1, Mmus\Sdf2, Mmus\Pomt2, Mmus\Pomt1" "Hsap\POMT2, Hsap\SDF2L1, Hsap\POMT1, Hsap\SDF2" FBgn0039421 CG6036 - http://flybase.org/reports/FBgn0039421 protein_coding_gene magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR012911 manganese ion binding ; GO:0030145 | inferred from electronic annotation with InterPro:IPR012911 protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity with SGD:S000000891 protein serine/threonine phosphatase activity ; GO:0004722 | non-traceable author statement protein dephosphorylation ; GO:0006470 | non-traceable author statement protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with SGD:S000000891 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000000891 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000000891 "PP2Cb, CG6036" "IPR000222:PPM-type phosphatase, divalent cation binding, IPR001932:PPM-type phosphatase domain, IPR012911:Protein serine/threonine phosphatase 2C, C-terminal, IPR015655:Protein phosphatase 2C family" CG6036 27-Aug-18 DroID_v2018_08 "Drer\ppm1bb, Drer\ppm1aa, Drer\ppm1ba, Drer\ppm1g, Drer\ppm1ab, Drer\ppm1na, Drer\ppm1nb" "Scer\PTC3, Scer\PTC2" "Cele\F42G9.1, Cele\ppm-1, Cele\ppm-2" "Xtro\ppm1b, Xtro\ppm1a" "Mmus\Ppm1b, Mmus\Ppm1a, Mmus\Ppm1g, Mmus\Ppm1n" "Hsap\PPM1B, Hsap\PPM1G, Hsap\PPM1N, Hsap\PPM1A" viable DRSC15953 E 1.142935774 0.347711612 0.50088674 1.54585224 -0.059358432 -1.013672335 FBgn0015882 anon-64Bd anon-64Bd http://flybase.org/reports/FBgn0015882 - gene - - - anon-64Bd - - 27-Aug-18 DroID_v2018_08 - - - - - - adult stage " leg

, adult head

, antenna

" FBgn0265104 lncRNA:CR44206 - http://flybase.org/reports/FBgn0265104 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG44206, CR44206, pri-mir-184" - CR44206 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033249 CG11191 - http://flybase.org/reports/FBgn0033249 protein_coding_gene - - - CG11191 IPR015943:WD40/YVTN repeat-like-containing domain CG11191 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC28710 K -0.741731338 -0.235065846 0.453517938 -0.425222631 1.759052613 0.816105004 FBgn0017384 l(1)15Fa lethal (1) 15Fa http://flybase.org/reports/FBgn0017384 - gene - - - l(1)15Fa - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0058174 CG40174 - http://flybase.org/reports/FBgn0058174 protein_coding_gene - - - CG40174 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263878 l(3)LVC73 - http://flybase.org/reports/FBgn0263878 gene - - - l(3)LVC73 - - 27-Aug-18 DroID_v2018_08 - - - - - - "mitotic cell cycle defective,lethal - all die before end of P-stage,recessive,some die during P-stage" "embryonic/larval neuroblast,embryonic/larval brain,embryonic/larval optic lobe" FBgn0058225 CG40225 - http://flybase.org/reports/FBgn0058225 protein_coding_gene - - - CG40225 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034144 CG5089 - http://flybase.org/reports/FBgn0034144 protein_coding_gene - - - "anon-WO0140519.170, CG5089" - CG5089 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0030543 CG11585 - http://flybase.org/reports/FBgn0030543 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG11585 - CG11585 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0285951 mRpS34 mitochondrial ribosomal protein S34 http://flybase.org/reports/FBgn0260460 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:P82930 structural constituent of ribosome ; GO:0003735 | traceable author statement translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:P82930 mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial small ribosomal subunit ; GO:0005763 | traceable author statement mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:P82930 "MRP-S34, CG13037, mRpS34, CG42648" IPR032053:Mitochondrial 28S ribosomal protein S34 CG42648 27-Aug-18 DroID_v2018_08 Drer\mrps34 - Cele\mrps-34 Xtro\mrps34 Mmus\Mrps34 Hsap\MRPS34 "viable,visible" trichogen cell FBgn0005705 l(1)TK108 lethal (1) TK108 http://flybase.org/reports/FBgn0005705 - gene - - - "l108, l(1)TK108" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0032154 mtDNA-helicase mitochondrial DNA helicase http://flybase.org/reports/FBgn0032154 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR007694 single-stranded DNA binding ; GO:0003697 | inferred from sequence or structural similarity with UniProtKB:Q96RR1 single-stranded DNA binding ; GO:0003697 | inferred from direct assay double-stranded DNA binding ; GO:0003690 | inferred from direct assay 5'-3' DNA helicase activity ; GO:0043139 | inferred from sequence or structural similarity with UniProtKB:Q96RR1 2 iron, 2 sulfur cluster binding ; GO:0051537 | inferred from direct assay" mitochondrial genome maintenance ; GO:0000002 | inferred from mutant phenotype mitochondrial DNA replication ; GO:0006264 | inferred from sequence or structural similarity with UniProtKB:Q96RR1 protein homooligomerization ; GO:0051260 | inferred from direct assay mitochondrial nucleoid ; GO:0042645 | inferred from sequence or structural similarity with UniProtKB:Q96RR1 mitochondrion ; GO:0005739 | inferred from direct assay "mtDNA-helicase, CG5924, mtDNA helicase" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR007694:DNA helicase, DnaB-like, C-terminal" CG5924 27-Aug-18 DroID_v2018_08 "Drer\peo1, Drer\poln" - Cele\F46G11.1 Xtro\c10orf2 "Mmus\Twnk, Mmus\Poln" "Hsap\POLN, Hsap\TWNK" "cell growth defective,viable,fertile,increased cell death,lethal - all die before end of larval stage,some die during third instar larval stage,lethal - all die before end of pupal stage,some die during pupal stage" "wing disc | third instar larval stage,wing disc,posterior compartment | third instar larval stage" FBgn0082961 snoRNA:Psi28S-3385b snoRNA:Psi28S-3385b http://flybase.org/reports/FBgn0082961 snoRNA_gene - - - "snoRNA:Psi28S-3385b, psi28s-3385b, CR34607" - CR34607 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266648 lncRNA:CR45155 - http://flybase.org/reports/FBgn0266648 non_protein_coding_gene - - - CR45155 - CR45155 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033523 CG12895 - http://flybase.org/reports/FBgn0033523 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "protein-FAD linkage ; GO:0018293 | inferred from sequence or structural similarity with UniProtKB:Q9NX18 mitochondrial electron transport, succinate to ubiquinone ; GO:0006121 | inferred from sequence or structural similarity with UniProtKB:Q9NX18 protein-FAD linkage ; GO:0018293 | inferred from biological aspect of ancestor with PANTHER:PTN002287625 mitochondrial electron transport, succinate to ubiquinone ; GO:0006121 | inferred from biological aspect of ancestor with PANTHER:PTN000279729 tricarboxylic acid cycle ; GO:0006099 | inferred from biological aspect of ancestor with PANTHER:PTN002287625 mitochondrial respiratory chain complex II assembly ; GO:0034553 | inferred from biological aspect of ancestor with PANTHER:PTN000279729" mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q9NX18 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000279729 "BcDNA:RE29446, CG12895" "IPR005631:Flavinator of succinate dehydrogenase, IPR028882:Succinate dehydrogenase assembly factor 2, mitochondrial" CG12895 27-Aug-18 DroID_v2018_08 Drer\sdhaf2 Scer\SDH5 Cele\Y57A10A.29 Xtro\sdhaf2 Mmus\Sdhaf2 Hsap\SDHAF2 "visible,partially lethal - majority die,some die during pupal stage,viable" "trichogen cell,mesothoracic tergum" FBgn0041125 l(2)45Al lethal (2) 45Al http://flybase.org/reports/FBgn0041125 gene - - - l(2)45Al - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0027336 l(1)40b lethal (1) 40b http://flybase.org/reports/FBgn0027336 - gene - - - l(1)40b - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0025681 CG3558 - http://flybase.org/reports/FBgn0025681 FBgn0031487 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "FBgn0025681, c4.3, BEST:LD23852, CG3558, LD23852" "IPR019384:Retinoic acid induced 16-like protein, IPR011989:Armadillo-like helical" CG3558 27-Aug-18 DroID_v2018_08 "Drer\fam160b1, Drer\fam160a2, Drer\fam160b2, Drer\fam160a1a" - Cele\C05D11.8 "Xtro\fam160b1, Xtro\fam160b2, Xtro\fam160a1, Xtro\fam160a2" "Mmus\Fam160a2, Mmus\Fam160a1, Mmus\Fam160b1, Mmus\Fam160b2" "Hsap\FAM160B2, Hsap\FAM160A2, Hsap\FAM160B1, Hsap\FAM160A1" FBgn0259162 RunxB Runt related B http://flybase.org/reports/FBgn0259162 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR008967, InterPro:IPR012346, InterPro:IPR013524 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000040 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR000040, InterPro:IPR012346, InterPro:IPR013524" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR000040, InterPro:IPR008967, InterPro:IPR012346, InterPro:IPR013524" "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR000040, InterPro:IPR012346" "CG42267, CG15455, CG15454, RunxB" "IPR000040:Acute myeloid leukemia 1 protein (AML1)/Runt, IPR008967:p53-like transcription factor, DNA-binding, IPR012346:p53/RUNT-type transcription factor, DNA-binding domain, IPR013524:Runt domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG42267 27-Aug-18 DroID_v2018_08 "Drer\runx3, Drer\runx2a, Drer\runx1, Drer\runx2b" - Cele\rnt-1 "Xtro\runx1, Xtro\runx3, Xtro\runx2" "Mmus\Runx2, Mmus\Runx1, Mmus\Runx3" "Hsap\RUNX1, Hsap\RUNX3, Hsap\RUNX2" FBgn0011055 l(1)Q8 lethal (1) Q8 http://flybase.org/reports/FBgn0011055 FBgn0010210 gene - - - l(1)Q8 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0028657 anon-1Ca anon-1Ca http://flybase.org/reports/FBgn0028657 gene - - - "X, anon-1Ca" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0082620 S(CycE[JP])47S8 S(CycE[JP])47S8 http://flybase.org/reports/FBgn0082620 gene - - - "47S8, S(CycE[JP])47S8" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0039820 CG15554 - http://flybase.org/reports/FBgn0039820 protein_coding_gene - - - "BcDNA:RE10288, CG15554" - CG15554 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0067635 188y 188y http://flybase.org/reports/FBgn0067635 gene - - - 188y - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile,courtship behavior defective,female" FBgn0031817 HemK1 - http://flybase.org/reports/FBgn0031817 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR002052 protein methyltransferase activity ; GO:0008276 | inferred from electronic annotation with InterPro:IPR004556 S-adenosylmethionine-dependent methyltransferase activity ; GO:0008757 | inferred from biological aspect of ancestor with PANTHER:PTN000430779 protein methylation ; GO:0006479 | inferred from electronic annotation with InterPro:IPR004556 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000430914 CG9531 "IPR002052:DNA methylase, N-6 adenine-specific, conserved site, IPR004556:Modification methylase HemK, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase, IPR007848:Methyltransferase small domain" CG9531 27-Aug-18 DroID_v2018_08 Drer\hemk1 "Scer\MTQ2, Scer\MTQ1" Cele\mtq-2 Xtro\hemk1 "Mmus\Hemk1, Mmus\N6amt1" "Hsap\N6AMT1, Hsap\HEMK1" DRSC03253 I -0.532977549 -1.501088159 0.798429161 -0.688992968 -0.755058209 -0.305129477 FBgn0027984 l(3)S133501b lethal (3) S133501b http://flybase.org/reports/FBgn0027984 gene - - - "1335/01, l(3)S133501, l(3)S133501b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0026654 l(2)2D8 lethal (2) 2D8 http://flybase.org/reports/FBgn0026654 - gene molecular_function ; GO:0003674 | no biological data available border follicle cell migration ; GO:0007298 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available l(2)2D8 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" "border follicle cell,somatic clone" FBgn0051501 nxf4 nuclear export factor 4 http://flybase.org/reports/FBgn0051501 protein_coding_gene - poly(A)+ mRNA export from nucleus ; GO:0016973 | inferred from biological aspect of ancestor with PANTHER:PTN000070434 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000070434 "BcDNA:AT07692, CG14604, CG31501, nxf4" "IPR030217:Nuclear RNA export factor, IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like" CG31501 27-Aug-18 DroID_v2018_08 "Drer\nxf1, Drer\zgc:153681" Scer\MEX67 "Cele\nxf-2, Cele\nxf-1" Xtro\nxf1 "Mmus\Nxf2, Mmus\Nxf7, Mmus\Nxf1, Mmus\Nxf3" "Hsap\NXF2B, Hsap\NXF5, Hsap\NXF3, Hsap\NXF2, Hsap\NXF1" viable DRSC12548 K 1.179127539 -0.356736203 0.547612129 -0.433458046 -1.572906876 -0.452319842 FBgn0053395 5SrRNA:CR33395 5SrRNA:CR33395 http://flybase.org/reports/FBgn0053395 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33395, 5SrRNA:CR33395" - CR33395 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0270928 VAChT Vesicular acetylcholine transporter http://flybase.org/reports/FBgn0270928 protein_coding_gene drug transmembrane transporter activity ; GO:0015238 | inferred from electronic annotation with InterPro:IPR004734 acetylcholine transmembrane transporter activity ; GO:0005277 | inferred from biological aspect of ancestor with PANTHER:PTN000607168 acetylcholine binding ; GO:0042166 | inferred from biological aspect of ancestor with PANTHER:PTN000607168 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 drug transport ; GO:0015893 | inferred from electronic annotation with InterPro:IPR004734 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001519445 AP-2 adaptor complex ; GO:0030122 | inferred from biological aspect of ancestor with PANTHER:PTN000607168 AP-1 adaptor complex ; GO:0030121 | inferred from biological aspect of ancestor with PANTHER:PTN000607168 "VAcht, vAChT, VAChT, VaChT, vacht, Vacht, CT41182, VACHT, CG12345, CG32848, VACht, Chn, chn" "IPR004734:Multidrug resistance protein, IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG32848 27-Aug-18 DroID_v2018_08 "Drer\slc18a2, Drer\slc18a1, Drer\slc18a3b, Drer\slc18a3a" - "Cele\unc-17, Cele\cat-1" "Xtro\slc18a1, Xtro\slc18a3" "Mmus\Slc18a2, Mmus\Slc18a1, Mmus\Slc18a3" "Hsap\SLC18A2, Hsap\SLC18A1, Hsap\SLC18A3" "chemical resistant,lethal,hypoactive,neurophysiology defective,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,wild-type,flight defective,locomotor behavior defective,viable,visible" "mesothoracic extracoxal depressor muscle 66,tormogen cell" FBgn0003227 rec recombination-defective http://flybase.org/reports/FBgn0003227 "FBgn0038367, FBgn0040563, FBgn0051293" protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001208 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001208 ATP-dependent DNA helicase activity ; GO:0004003 | traceable author statement ATPase activity ; GO:0016887 | traceable author statement DNA-dependent ATPase activity ; GO:0008094 | traceable author statement DNA replication ; GO:0006260 | inferred from electronic annotation with InterPro:IPR001208 reciprocal meiotic recombination ; GO:0007131 | inferred from mutant phenotype DNA replication initiation ; GO:0006270 | traceable author statement nucleus ; GO:0005634 | traceable author statement "CG31293, rec1, rec-1, CG4828, CG14875, rec, MCM8" "IPR001208:MCM domain, IPR012340:Nucleic acid-binding, OB-fold, IPR033762:MCM OB domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR031327:Mini-chromosome maintenance protein" CG31293 27-Aug-18 DroID_v2018_08 "Drer\mcm8, Drer\mcm6l, Drer\mcm6, Drer\mcmdc2" "Scer\MCM2, Scer\MCM6" Cele\mcm-2 "Xtro\mcm8, Xtro\mcm6, Xtro\mcm6.2" "Mmus\Mcm8, Mmus\Mcm6, Mmus\Mcmdc2" "Hsap\MCMDC2, Hsap\MCM8, Hsap\MCM6" "sterile,heat sensitive,viable" FBgn0040869 CG15763 - http://flybase.org/reports/FBgn0040869 protein_coding_gene - - - CG15763 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035941 CG13313 - http://flybase.org/reports/FBgn0035941 protein_coding_gene - - - CG13313 IPR000859:CUB domain CG13313 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC09984 E 0.901828643 -0.468383896 -1.581960268 -0.10091293 -0.007886799 1.117119912 FBgn0039215 CG6695 - http://flybase.org/reports/FBgn0039215 protein_coding_gene - - - CG6695 IPR019147:Suppressor of white apricot N-terminal domain CG6695 27-Aug-18 DroID_v2018_08 Drer\clasrp - "Cele\taf-3, Cele\F28C1.1" Xtro\clasrp Mmus\Clasrp Hsap\CLASRP "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0052804 CG32804 - http://flybase.org/reports/FBgn0052804 protein_coding_gene - - - CG32804 - - 27-Aug-18 DroID_v2018_08 - - - - - - DRSC21314 I 0.926660174 -1.842050949 0.210266771 -0.020597241 0.431697099 0.079495767 FBgn0052248 CG32248 - http://flybase.org/reports/FBgn0052248 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32248 IPR004011:GYR motif CG32248 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" FBgn0264944 lncRNA:CR44113 - http://flybase.org/reports/FBgn0264944 non_protein_coding_gene - - - CR44113 - CR44113 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065619 l(2)SH0806 lethal (2) SH0806 http://flybase.org/reports/FBgn0065619 gene - - - "l(2)SH0806, l(2)SH2 0806" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0260230 CG42504 - http://flybase.org/reports/FBgn0260230 protein_coding_gene - - - CG42504 - CG42504 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0003047 pcv posterior crossvein http://flybase.org/reports/FBgn0003047 - gene - - - pcv - - 27-Aug-18 DroID_v2018_08 - - - - - - visible wing FBgn0264414 FCE-G - http://flybase.org/reports/FBgn0264414 gene - - - FCE-G - - 27-Aug-18 DroID_v2018_08 - - - - - - "egg chamber,somatic clone" FBgn0039223 CG5805 - http://flybase.org/reports/FBgn0039223 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR002067 mitochondrial transport ; GO:0006839 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 integral component of mitochondrial outer membrane ; GO:0031307 | inferred from biological aspect of ancestor with PANTHER:PTN000640716 CG5805 "IPR002067:Mitochondrial carrier protein, IPR018108:Mitochondrial substrate/solute carrier, IPR023395:Mitochondrial carrier domain" CG5805 27-Aug-18 DroID_v2018_08 "Drer\slc25a44b, Drer\slc25a44a" "Scer\UGO1, Scer\AGC1" "Cele\F13G3.7, Cele\Y43C5B.3" Xtro\slc25a44 Mmus\Slc25a44 Hsap\SLC25A44 viable DRSC15878 E -0.347565075 -0.328281302 -1.978301092 0.295757719 0.179944278 -0.057406919 FBgn0263030 CG43325 - http://flybase.org/reports/FBgn0263030 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG13514, CG30217, CG43325" - CG43325 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0003096 Pearl Pearl http://flybase.org/reports/FBgn0003096 - gene - - - "Pl, Pearl" - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,male fertile,reduced,lethal - all die before end of pupal stage,some die during pupal stage" "wing,heat sensitive,wing vein,eye,wing margin,macrochaeta,imaginal disc" FBgn0032322 CG16743 - http://flybase.org/reports/FBgn0032322 protein_coding_gene - - - "BcDNA:RH23514, CG16743" - CG16743 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0029754 CG15930 - http://flybase.org/reports/FBgn0029754 protein_coding_gene - - - CG15930 IPR002999:Tudor domain CG15930 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0065248 l(2)SH2136 lethal (2) SH2136 http://flybase.org/reports/FBgn0065248 gene - - - l(2)SH2136 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0004039 yea5 yeast 5 http://flybase.org/reports/FBgn0004039 - gene - - - yea5 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031836 CG11050 - http://flybase.org/reports/FBgn0031836 protein_coding_gene - sleep ; GO:0030431 | inferred from expression pattern - "BcDNA:LD22339, CG11050" IPR006674:HD domain CG11050 27-Aug-18 DroID_v2018_08 Drer\hddc2 "Scer\YBR242W, Scer\YGL101W" Cele\F45F2.9 Xtro\hddc2 Mmus\Hddc2 Hsap\HDDC2 viable FBgn0001713 l(1)ESHS34 lethal (1) ESHS34 http://flybase.org/reports/FBgn0001713 - gene - - - l(1)ESHS34 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0267708 lncRNA:CR46041 - http://flybase.org/reports/FBgn0267708 non_protein_coding_gene - - - CR46041 - CR46041 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036751 Adgf-B Adenosine deaminase-related growth factor B http://flybase.org/reports/FBgn0036751 protein_coding_gene "growth factor activity ; GO:0008083 | inferred from sequence or structural similarity with Adgf-A, Adgf-D adenosine deaminase activity ; GO:0004000 | inferred from sequence or structural similarity with Adgf-A, Adgf-D" "adenosine catabolic process ; GO:0006154 | inferred from sequence or structural similarity with Adgf-A, Adgf-D cell proliferation ; GO:0008283 | inferred from sequence or structural similarity with Adgf-A, Adgf-D" "extracellular space ; GO:0005615 | inferred from electronic annotation with InterPro:IPR006331, InterPro:IPR013659" "CG5998, ADGF-B, adgfb, Adgf-B, AdgfB" "IPR001365:Adenosine/AMP deaminase domain, IPR006331:Adenosine deaminase-related growth factor, IPR013659:Adenosine/AMP deaminase N-terminal, IPR032466:Metal-dependent hydrolase" CG5998 27-Aug-18 DroID_v2018_08 "Drer\ada, Drer\adal, Drer\cecr1b, Drer\cecr1a" Scer\AAH1 - "Xtro\adal, Xtro\ada.2, Xtro\cecr1, Xtro\ada" "Mmus\Ada, Mmus\Adal" "Hsap\ADAL, Hsap\ADA, Hsap\CECR1" viable DRSC24118 K -0.369158908 -0.498485012 0.609054545 -0.203045716 1.555637884 0.143069404 FBgn0285879 disco-r disco-related http://flybase.org/reports/FBgn0285879 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 molecular_function ; GO:0003674 | no biological data available imaginal disc-derived wing expansion ; GO:0048526 | inferred from mutant phenotype epithelial to mesenchymal transition ; GO:0001837 | inferred from mutant phenotype delamination ; GO:0060232 | inferred from mutant phenotype wing disc morphogenesis ; GO:0007472 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "disco-r, bae, CG9223, CG9219, CG32577" IPR013087:Zinc finger C2H2-type CG32577 27-Aug-18 DroID_v2018_08 "Drer\bnc1, Drer\bnc2" - Cele\bnc-1 "Xtro\bnc1, Xtro\bnc2" "Mmus\Bnc2, Mmus\Bnc1" "Hsap\BNC2, Hsap\BNC1" "viable,fertile,visible,semidominant" "wing,cell non-autonomous" FBgn0053054 CG33054 - http://flybase.org/reports/FBgn0053054 protein_coding_gene purine nucleoside binding ; GO:0001883 | inferred from sequence or structural similarity with HGNC:21257 purine nucleoside metabolic process ; GO:0042278 | inferred from sequence or structural similarity with HGNC:21257 cellular_component ; GO:0005575 | no biological data available "CG10517, CG10167, CG33054" IPR002589:Macro domain CG33054 27-Aug-18 DroID_v2018_08 "Drer\zgc:113436, Drer\oard1" Scer\POA1 "Cele\W08F4.12, Cele\fbxb-37, Cele\F54G2.2" - Mmus\Oard1 Hsap\OARD1 "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" FBgn0038499 Brf Brf http://flybase.org/reports/FBgn0038499 protein_coding_gene TFIIIB-type transcription factor activity ; GO:0001026 | inferred from electronic annotation with InterPro:IPR029529 TBP-class protein binding ; GO:0017025 | inferred from electronic annotation with InterPro:IPR013150 transcription factor binding ; GO:0008134 | inferred from physical interaction with Trf core promoter sequence-specific DNA binding ; GO:0001046 | contributes_to inferred from physical interaction with Trf DNA-templated transcriptional preinitiation complex assembly ; GO:0070897 | inferred from electronic annotation with InterPro:IPR000812 transcription from RNA polymerase III promoter ; GO:0006383 | inferred from direct assay neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype regulation of transcription from RNA polymerase III promoter ; GO:0006359 | inferred from direct assay inferred from physical interaction with Trf regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype transcription factor TFIIIB complex ; GO:0000126 | inferred from electronic annotation with InterPro:IPR029529 transcription factor complex ; GO:0005667 | inferred from physical interaction with Trf "Brf, BRF, TFIIIB, BRF1, CG5419, CG4155, CG31256, brf, Brf1" "IPR000812:Transcription factor TFIIB, IPR011665:Brf1, TBP-binding domain, IPR013137:Zinc finger, TFIIB-type, IPR013150:Transcription factor TFIIB, cyclin-like domain, IPR013763:Cyclin-like, IPR029529:Transcription factor IIIB subunit Brf1" CG31256 27-Aug-18 DroID_v2018_08 "Drer\brf2, Drer\LOC100536580, Drer\brf1b, Drer\brf1a" Scer\BRF1 Cele\brf-1 Xtro\brf1 "Mmus\Brf2, Mmus\Brf1" "Hsap\BRF1, Hsap\BRF2" "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" embryonic/larval brain FBgn0004022 Wr Wrinkle http://flybase.org/reports/FBgn0004022 - gene - - - Wr - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,recessive,developmental rate defective" wing FBgn0063925 Jra::kay Jra::kay http://flybase.org/reports/FBgn0063925 engineered_fusion_gene - - - Jra::kay - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266252 lncRNA:CR44947 - http://flybase.org/reports/FBgn0266252 non_protein_coding_gene - - - "CR44947, lincRNA.822" - CR44947 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266577 asRNA:CR45108 - http://flybase.org/reports/FBgn0266577 non_protein_coding_gene - - - CR45108 - CR45108 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036661 CG9705 - http://flybase.org/reports/FBgn0036661 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR002059 mRNA 3'-UTR binding ; GO:0003730 | inferred from biological aspect of ancestor with PANTHER:PTN000311282 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR002059 regulation of mRNA stability ; GO:0043488 | inferred from biological aspect of ancestor with PANTHER:PTN000311282 dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000311282 CG9705 "IPR002059:Cold-shock protein, DNA-binding, IPR011129:Cold shock domain, IPR012340:Nucleic acid-binding, OB-fold, IPR019844:Cold-shock conserved site" CG9705 27-Aug-18 DroID_v2018_08 "Drer\lin28a, Drer\csdc2b, Drer\si:ch1073-284b18.2, Drer\ybx1, Drer\carhsp1, Drer\csdc2a" - - "Xtro\ybx1, Xtro\ybx3, Xtro\lin28b, Xtro\carhsp1, Xtro\lin28a, Xtro\csdc2, Xtro\ybx2" "Mmus\Carhsp1, Mmus\Ybx2, Mmus\Lin28a, Mmus\Csdc2, Mmus\Ybx3, Mmus\Ybx1, Mmus\Lin28b" "Hsap\CSDC2, Hsap\LIN28A, Hsap\YBX2, Hsap\YBX1, Hsap\YBX3, Hsap\LIN28B, Hsap\CARHSP1" "neuroanatomy defective,viable" "dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa,ventral multidendritic neuron vdaB" FBgn0024904 anon-I7114 anon-I7114 http://flybase.org/reports/FBgn0024904 - gene - - - "cDNA I7114, anon-I7114" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0022711 61bis 61bis http://flybase.org/reports/FBgn0022711 - gene - - - 61bis - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0017625 Eig58C Eig58C http://flybase.org/reports/FBgn0017625 - gene - - - "Eig58, Eig58C" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266880 asRNA:CR45341 - http://flybase.org/reports/FBgn0266880 non_protein_coding_gene - - - CR45341 - CR45341 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001535 l(1)14Ba lethal (1) 14Ba http://flybase.org/reports/FBgn0001535 - gene - - - l(1)14Ba - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0036875 CG9449 - http://flybase.org/reports/FBgn0036875 protein_coding_gene acid phosphatase activity ; GO:0003993 | inferred from sequence or structural similarity with HGNC:125 phagocytosis ; GO:0006909 | inferred from mutant phenotype dephosphorylation ; GO:0016311 | inferred from sequence or structural similarity with HGNC:125 extracellular exosome ; GO:0070062 | inferred from sequence or structural similarity with HGNC:125 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:125 CG9449 "IPR000560:Histidine phosphatase superfamily, clade-2, IPR029630:Venom acid phosphatase Acph-1, IPR029033:Histidine phosphatase superfamily, IPR033379:Histidine acid phosphatase active site" CG9449 27-Aug-18 DroID_v2018_08 "Drer\pxylp1, Drer\acp2, Drer\acp6" - "Cele\acp-3, Cele\pho-14, Cele\pho-11, Cele\F26C11.1, Cele\acp-5, Cele\pho-13, Cele\pho-7, Cele\pho-8, Cele\pho-9, Cele\acp-6, Cele\pho-1, Cele\acp-4, Cele\acp-1, Cele\pho-5, Cele\pho-12, Cele\acp-7, Cele\ZK792.1, Cele\ZK809.9, Cele\pho-10, Cele\acp-2, Cele\pho-6, Cele\C27A2.12, Cele\pho-4" "Xtro\acp6, Xtro\acp2, Xtro\LOC100494856" "Mmus\Acp2, Mmus\Pxylp1, Mmus\Acpt, Mmus\Acp6, Mmus\Acpp" "Hsap\ACPP, Hsap\PXYLP1, Hsap\ACPT, Hsap\ACP6, Hsap\ACP2" viable FBgn0004422 gustC gustatory-defective C http://flybase.org/reports/FBgn0004422 "FBgn0001155, FBgn0001160" gene - - - "gust[x2], gusB, gustC" - - 27-Aug-18 DroID_v2018_08 - - - - - - "taste perception defective,recessive" FBgn0025127 su(RpII140[Z36])S2 su(RpII140[Z36])S2 http://flybase.org/reports/FBgn0025127 - gene - - - "Z36[S2], su(RpII140[Z36])S2" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040768 CG13234 - http://flybase.org/reports/FBgn0040768 protein_coding_gene - - - CG13234 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037877 CG6689 - http://flybase.org/reports/FBgn0037877 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR006612, InterPro:IPR013087" - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 "dmCG6689, CG6689" "IPR006612:Zinc finger, C2CH-type, IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG6689 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-241b2.4, Drer\wt1a, Drer\znf408, Drer\wt1b" Scer\AZF1 "Cele\M03D4.4, Cele\Y55F3AM.14, Cele\klf-2, Cele\zfp-2, Cele\eor-1" - "Mmus\Zfp352, Mmus\Zfp810, Mmus\Klf17, Mmus\Rbak, Mmus\Zfp296, Mmus\Zfp691, Mmus\Wt1, Mmus\Klf1" "Hsap\ZNF296, Hsap\ZNF691, Hsap\ZNF560, Hsap\KLF17, Hsap\WT1, Hsap\KLF1, Hsap\ZNF281, Hsap\ZNF8" "partially lethal - majority die,some die during pupal stage" FBgn0260467 CG7071 - http://flybase.org/reports/FBgn0260467 protein_coding_gene - - endomembrane system ; GO:0012505 | inferred from direct assay "BcDNA:RE40914, CG7071, Dromel_CG7071_FBtr0084211_mORF" "IPR021013:ATPase, vacuolar ER assembly factor, Vma12" CG7071 27-Aug-18 DroID_v2018_08 Drer\tmem199 Scer\VPH2 Cele\F09E5.11 Xtro\tmem199 Mmus\Tmem199 Hsap\TMEM199 FBgn0013532 l(2)35Ab lethal (2) 35Ab http://flybase.org/reports/FBgn0013532 - gene - - - l(2)35Ab - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0038523 CG7587 - http://flybase.org/reports/FBgn0038523 protein_coding_gene - - - CG7587 - CG7587 27-Aug-18 DroID_v2018_08 - - Cele\F46F5.16 - - - viable FBgn0060939 l(3)S040428b lethal (3) S040428b http://flybase.org/reports/FBgn0060939 gene - - - "0404/28, l(3)S040428b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0032360 CG14926 - http://flybase.org/reports/FBgn0032360 protein_coding_gene - - - "bs34f02.y1, CG14926" - CG14926 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0001718 l(1)ESHS39 lethal (1) ESHS39 http://flybase.org/reports/FBgn0001718 - gene - - - l(1)ESHS39 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0038894 CG15497 - http://flybase.org/reports/FBgn0038894 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available extracellular space ; GO:0005615 | inferred from sequence or structural similarity with to CG15497 "IPR023393:START-like domain, IPR010562:Haemolymph juvenile hormone binding" CG15497 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0032827 CG10481 - http://flybase.org/reports/FBgn0032827 protein_coding_gene - - integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR004342 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000081883 CG10481 "IPR004331:SPX domain, IPR004342:EXS, C-terminal" CG10481 27-Aug-18 DroID_v2018_08 "Drer\xpr1b, Drer\xpr1a" "Scer\SYG1, Scer\VTC3, Scer\ERD1, Scer\VTC4, Scer\VTC2" Cele\Y39A1A.22 Xtro\xpr1 Mmus\Xpr1 Hsap\XPR1 viable FBgn0037621 M1BP Motif 1 Binding Protein http://flybase.org/reports/FBgn0037621 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 RNA polymerase II core promoter sequence-specific DNA binding ; GO:0000979 | inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN001227002" "positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with Ras85D positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from genetic interaction with Ras85D ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype RNA polymerase II transcriptional preinitiation complex assembly ; GO:0051123 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from biological aspect of ancestor with PANTHER:PTN001227002 mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001227002 "CG9797, M1BP, CC31" "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type" CG9797 27-Aug-18 DroID_v2018_08 "Drer\bcl6ab, Drer\znf408, Drer\znf770, Drer\znf341" Scer\AZF1 "Cele\M03D4.4, Cele\eor-1, Cele\ztf-23, Cele\Y55F3AM.14, Cele\blmp-1, Cele\Y37F4.6, Cele\hbl-1, Cele\klf-3" - "Mmus\Zkscan8, Mmus\Zfp341, Mmus\Zfp708, Mmus\Zfp24, Mmus\Zfp810, Mmus\Rbak, Mmus\Zfp369, Mmus\Gm13212, Mmus\Zfp945, Mmus\Zfp12, Mmus\Zfp110, Mmus\Zbtb14, Mmus\Zfp984, Mmus\Zfp93, Mmus\Zscan5b, Mmus\Zfp758, Mmus\Zfp445" "Hsap\ZNF98, Hsap\ZNF485, Hsap\ZNF784, Hsap\ZNF28, Hsap\ZNF850, Hsap\ZNF595, Hsap\ZNF558, Hsap\ZNF211, Hsap\ZNF527, Hsap\ZNF570, Hsap\ZNF816, Hsap\ZNF480, Hsap\ZSCAN30, Hsap\ZNF560, Hsap\ZNF492, Hsap\ZNF221, Hsap\ZNF284, Hsap\RBAK-RBAKDN, Hsap\ZNF341, Hsap\ZNF281, Hsap\ZNF233, Hsap\ZNF568, Hsap\ZNF845, Hsap\ZNF117, Hsap\ZNF721, Hsap\ZNF730, Hsap\ZNF121, Hsap\ZFP28, Hsap\ZNF43" FBgn0052383 sphinx1 sphinx1 http://flybase.org/reports/FBgn0052383 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254 defense response to Gram-positive bacterium ; GO:0050830 | inferred from mutant phenotype multicellular organism reproduction ; GO:0032504 | inferred from expression pattern defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype positive regulation of Toll signaling pathway ; GO:0045752 | inferred from mutant phenotype innate immune response ; GO:0045087 | inferred from mutant phenotype defense response to fungus ; GO:0050832 | inferred from mutant phenotype extracellular region ; GO:0005576 | inferred by curator from GO:0050832 "SPH194, CG8555, sphinx1, CG32383, Sphinx-1, Sphinx1" "IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan" CG32383 27-Aug-18 DroID_v2018_08 "Drer\masp2, Drer\LOC562139, Drer\ela3l" - - Xtro\prtn3 "Mmus\Hgf, Mmus\Klk1b3, Mmus\C1s1, Mmus\C1s2" Hsap\C1S "immune response defective,partially lethal - majority die,some die during pupal stage" FBgn0052413 CG32413 - http://flybase.org/reports/FBgn0052413 protein_coding_gene - - - "CG10487, CG32413" IPR007484:Peptidase M28 CG32413 27-Aug-18 DroID_v2018_08 "Drer\qpct, Drer\qpctla, Drer\qpctlb" Scer\YFR018C Cele\H27A22.1 "Xtro\qpctl, Xtro\qpct" "Mmus\Qpctl, Mmus\Qpct" "Hsap\QPCT, Hsap\QPCTL" viable FBgn0060521 l(3)S102409 lethal (3) S102409 http://flybase.org/reports/FBgn0060521 gene - - - "1024/09, l(3)S102409" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0263900 l(3)B29 - http://flybase.org/reports/FBgn0263900 gene - - - l(3)B29 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,decreased cell number,somatic clone" "embryonic/larval brain,somatic clone" FBgn0086708 stv starvin http://flybase.org/reports/FBgn0086708 protein_coding_gene chaperone binding ; GO:0051087 | inferred from electronic annotation with InterPro:IPR003103 heat shock protein binding ; GO:0031072 | inferred from physical interaction with Hsp67Bc positive regulation of protein lipidation ; GO:1903061 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from direct assay Z disc ; GO:0030018 | inferred from direct assay "CG32130, GH04349, l(3)00543, CG14108, CG10745, stv, Stv, cg32130" IPR003103:BAG domain CG32130 27-Aug-18 DroID_v2018_08 "Drer\bag5, Drer\bag3, Drer\bag4" - - "Xtro\bag4, Xtro\bag3, Xtro\tet2, Xtro\bag5" "Mmus\Bag5, Mmus\Bag4, Mmus\Bag3" "Hsap\BAG5, Hsap\BAG4, Hsap\BAG3" FBgn0037943 CG14722 - http://flybase.org/reports/FBgn0037943 protein_coding_gene - defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype rRNA processing ; GO:0006364 | inferred from biological aspect of ancestor with PANTHER:PTN002336300 ribosomal large subunit biogenesis ; GO:0042273 | inferred from biological aspect of ancestor with PANTHER:PTN002336300 - CG14722 "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR019775:WD40 repeat, conserved site, IPR024977:Anaphase-promoting complex subunit 4, WD40 domain" CG14722 27-Aug-18 DroID_v2018_08 "Drer\ik, Drer\wdr55" Scer\JIP5 "Cele\Y44F5A.1, Cele\smu-2" Xtro\wdr55 "Mmus\Ik, Mmus\Wdr55" "Hsap\IK, Hsap\WDR55" viable FBgn0028662 VhaPPA1-1 Vacuolar H[+] ATPase PPA1 subunit 1 http://flybase.org/reports/FBgn0028662 protein_coding_gene "proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | contributes_to inferred by curator from GO:0033181 proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from biological aspect of ancestor with PANTHER:PTN000813763 hydrogen ion transmembrane transporter activity ; GO:0015078 | inferred from sequence model with InterPro:IPR000245,InterPro:IPR002379" "ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from electronic annotation with InterPro:IPR000245, InterPro:IPR002379 vacuolar acidification ; GO:0007035 | inferred from biological aspect of ancestor with PANTHER:PTN000029540 terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype ATP hydrolysis coupled proton transport ; GO:0015991 | inferred by curator from GO:0033181" "vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220 | inferred from sequence or structural similarity with SGD:S000001068 vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220 | inferred from biological aspect of ancestor with PANTHER:PTN000029540 plasma membrane proton-transporting V-type ATPase complex ; GO:0033181 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000813763" "CG7007, vhaPPA1-1, VhaPPA1-1, VhaPPA1, Vha26, V0c''" "IPR000245:V-ATPase proteolipid subunit, IPR002379:V-ATPase proteolipid subunit C-like domain" CG7007 27-Aug-18 DroID_v2018_08 Drer\atp6v0b "Scer\VMA16, Scer\VMA3" Cele\vha-4 Xtro\atp6v0b Mmus\Atp6v0b Hsap\ATP6V0B "lethal,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die,visible,body color defective" "chaeta,supernumerary,mesothoracic tergum" FBgn0260304 GSd460 - http://flybase.org/reports/FBgn0260304 gene - - - GSd460 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0259567 GG01019 - http://flybase.org/reports/FBgn0259567 gene - - - GG01019 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible wing vein L3 FBgn0262714 Sap130 Sin3A-associated protein 130 http://flybase.org/reports/FBgn0262714 protein_coding_gene transcription coactivator activity ; GO:0003713 | inferred from biological aspect of ancestor with PANTHER:PTN001004204 histone acetyltransferase activity ; GO:0004402 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001004204 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR024137 histone H3 acetylation ; GO:0043966 | inferred from biological aspect of ancestor with PANTHER:PTN001004204 regulation of gene expression ; GO:0010468 | inferred from biological aspect of ancestor with PANTHER:PTN001004204" nucleoplasm ; GO:0005654 | inferred from direct assay STAGA complex ; GO:0030914 | inferred from biological aspect of ancestor with PANTHER:PTN001004204 Sin3-type complex ; GO:0070822 | inferred from direct assay "BcDNA:LD21213, Sap130, CG11006, SAP130, l(3)06924" "IPR024137:Histone deacetylase complex subunit SAP130, IPR031963:Histone deacetylase complex subunit SAP130, C-terminal domain" CG11006 27-Aug-18 DroID_v2018_08 "Drer\sap130b, Drer\sap130a" - - Xtro\sap130 Mmus\Sap130 Hsap\SAP130 FBgn0038243 CG8066 - http://flybase.org/reports/FBgn0038243 protein_coding_gene cysteine-type endopeptidase inhibitor activity ; GO:0004869 | inferred from electronic annotation with InterPro:IPR000010 - - CG8066 IPR000010:Cystatin domain CG8066 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC24633 K 0.657644418 -0.293798388 -0.122258226 -0.046606411 0.444985774 2.018870972 FBgn0011982 tRNA:Ser-AGA-2-1 transfer RNA:Serine-AGA 2-1 http://flybase.org/reports/FBgn0011982 "FBgn0003830, FBgn0011968, FBgn0011979, FBgn0052607, FBgn0060068" tRNA_gene UCU codon-amino acid adaptor activity ; GO:0033405 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033405 cytosol ; GO:0005829 | inferred by curator from GO:0033405 "444-3, tRNA ser7, 777-1, Ser-tRNA-7, tRNA[Ser][[7]], tRNA[[7]][Ser], tRNA[Ser], AE002593.trna14-SerAGA, tRNA:S:AGA:AE002593-d, CR32607, tRNA:ser, tRNA:S, tRNA:S7, tRNA:ser7, tRNA:ser7:12Ed, tRNA[[Ser]], chrX.trna23-SerAGA, tRNA-Ser-AGA-2-1, tRNA:Ser-AGA-2-1, tRNA:S7:12Ed, UCU" - CR32607 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0044066 GT49-2-4 GT49-2-4 http://flybase.org/reports/FBgn0044066 gene - - - GT49-2-4 - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0041000 CG15476 - http://flybase.org/reports/FBgn0041000 protein_coding_gene - - - "38D.5, CG15476" - - 27-Aug-18 DroID_v2018_08 - - - - - - DRSC02487 IEK 1.516561193 0.629525125 2.00835376 -3.06981675 0.42644284 1.605097904 FBgn0043874 nad1 nurse cell apoptosis defective-1 http://flybase.org/reports/FBgn0043874 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "nad-1, nad1" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036671 CG9951 - http://flybase.org/reports/FBgn0036671 protein_coding_gene cullin family protein binding ; GO:0097602 | inferred from biological aspect of ancestor with PANTHER:PTN000402481 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:2000060 | inferred from biological aspect of ancestor with PANTHER:PTN000402481 - CG9951 "IPR008530:Coiled-coil domain-containing protein 22, IPR015866:Serine-tRNA synthetase, type1, N-terminal" CG9951 27-Aug-18 DroID_v2018_08 Drer\ccdc22 - Cele\R08E3.3 Xtro\ccdc22 Mmus\Ccdc22 Hsap\CCDC22 viable FBgn0031842 Tango1 Transport and Golgi organization 1 http://flybase.org/reports/FBgn0031842 protein_coding_gene chaperone binding ; GO:0051087 | inferred from electronic annotation with InterPro:IPR003103 molecular_function ; GO:0003674 | no biological data available secretory granule organization ; GO:0033363 | inferred from mutant phenotype Golgi organization ; GO:0007030 | inferred from mutant phenotype protein secretion ; GO:0009306 | inferred from mutant phenotype positive regulation of secretion ; GO:0051047 | inferred from mutant phenotype endomembrane system ; GO:0012505 | inferred from direct assay endoplasmic reticulum exit site ; GO:0070971 | inferred from direct assay Golgi cis cisterna ; GO:0000137 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay "CG11098, TANGO1, Tango1, tango1" IPR003103:BAG domain CG11098 27-Aug-18 DroID_v2018_08 "Drer\mia, Drer\mia3, Drer\mia2" - - Xtro\ctage5 "Mmus\Spz1, Mmus\Mia2, Mmus\Otor, Mmus\Mia, Mmus\Mia3" "Hsap\CTAGE9, Hsap\MIA, Hsap\OTOR, Hsap\CTAGE8, Hsap\CTAGE6, Hsap\MIA3, Hsap\SPZ1, Hsap\CTAGE15, Hsap\CTAGE1, Hsap\CTAGE4, Hsap\MIA2" "lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval proventriculus outer layer,secretory granuleunspecified" DRSC27972 K -0.490480529 -0.238042993 -0.191774262 -0.468782202 -0.216851909 2.287234091 FBgn0034030 CG8192 - http://flybase.org/reports/FBgn0034030 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG8192 IPR002557:Chitin binding domain CG8192 27-Aug-18 DroID_v2018_08 - - Cele\Y56A3A.6 - - - viable DRSC07101 IE -1.118523549 -2.663406072 -0.335582856 -2.05762204 -0.293378602 -0.556071573 FBgn0031288 CG13949 - http://flybase.org/reports/FBgn0031288 protein_coding_gene - - - "BcDNA:AT06839, CG13949" - CG13949 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC00367 K 0.139036982 -0.592194996 -0.038950647 0.52576729 1.932551119 -0.115599557 FBgn0267461 lncRNA:CR45811 - http://flybase.org/reports/FBgn0267461 non_protein_coding_gene - - - CR45811 - CR45811 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0020442 Eric Ecdysone receptor interacting co-repressor http://flybase.org/reports/FBgn0020442 - gene - - cellular_component ; GO:0005575 | no biological data available Eric - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038666 Smu1 Smu1 spliceosomal factor http://flybase.org/reports/FBgn0038666 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype terminal button organization ; GO:0072553 | inferred from mutant phenotype neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype" precatalytic spliceosome ; GO:0071011 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "Smu1, CG5451, dsmu1" "IPR001680:WD40 repeat, IPR006594:LIS1 homology motif, IPR006595:CTLH, C-terminal LisH motif, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat" CG5451 27-Aug-18 DroID_v2018_08 "Drer\smu1a, Drer\smu1b" "Scer\PRP46, Scer\UTP13" "Cele\smu-1, Cele\dyci-1" Xtro\smu1 Mmus\Smu1 Hsap\SMU1 "neuroanatomy defective,neurophysiology defective,viable" NMJ bouton FBgn0267471 lncRNA:CR45821 - http://flybase.org/reports/FBgn0267471 non_protein_coding_gene - - - CR45821 - CR45821 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001591 l(1)carot8 lethal (1) carot8 http://flybase.org/reports/FBgn0001591 - gene - - - l(1)carot8 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0001726 l(1)ESHS47 lethal (1) ESHS47 http://flybase.org/reports/FBgn0001726 - gene - - - l(1)ESHS47 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0020595 anon-57Cb anon-57Cb http://flybase.org/reports/FBgn0020595 - gene - - - anon-57Cb - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039673 CG7568 - http://flybase.org/reports/FBgn0039673 protein_coding_gene - - intracellular ; GO:0005622 | inferred from biological aspect of ancestor with PANTHER:PTN001483500 CG7568 "IPR019775:WD40 repeat, conserved site, IPR001680:WD40 repeat, IPR020472:G-protein beta WD-40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG7568 27-Aug-18 DroID_v2018_08 "Drer\prpf4, Drer\daw1, Drer\fbxw11a, Drer\fbxw7, Drer\fbxw11b, Drer\wdr5, Drer\ahi1" "Scer\CDC4, Scer\MET30, Scer\PRP4" "Cele\sel-10, Cele\wdr-5.1, Cele\Y44F5A.1, Cele\lin-23" "Xtro\btrc, Xtro\fbxw7, Xtro\prpf4, Xtro\daw1" "Mmus\Fbxw11, Mmus\Fbxw7, Mmus\Ahi1, Mmus\Daw1, Mmus\Btrc, Mmus\Wdr5, Mmus\Wdr5b, Mmus\Prpf4" "Hsap\WDR5B, Hsap\FBXW11, Hsap\DAW1, Hsap\PRPF4, Hsap\BTRC, Hsap\WDR5, Hsap\FBXW7, Hsap\AHI1" viable FBgn0036108 Cpr67Fa1 Cuticular protein 67Fa1 http://flybase.org/reports/FBgn0036108 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "BcDNA:RE57116, Cpr67Fa1, CG7941, DmelCpr67Fa1" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG7941 27-Aug-18 DroID_v2018_08 Drer\LOC100003040 - "Cele\sdz-30, Cele\math-34, Cele\F44F1.4" - "Mmus\H2-K1, Mmus\2410137M14Rik" - FBgn0261456 hpo hippo http://flybase.org/reports/FBgn0261456 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 kinase activity ; GO:0016301 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with yki protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay protein homodimerization activity ; GO:0042803 | inferred from physical interaction with hpo protein binding ; GO:0005515 | inferred from physical interaction with Rassf inferred from physical interaction with sav protein binding ; GO:0005515 | inferred from physical interaction with ex receptor signaling protein serine/threonine kinase activity ; GO:0004702 | inferred from biological aspect of ancestor with PANTHER:PTN000684825 receptor signaling protein serine/threonine kinase activity ; GO:0004702 | non-traceable author statement" "regulation of apoptotic signaling pathway ; GO:2001233 | inferred from mutant phenotype cell proliferation ; GO:0008283 | inferred from mutant phenotype negative regulation of canonical Wnt signaling pathway ; GO:0090090 | inferred from mutant phenotype apoptotic process ; GO:0006915 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement protein autophosphorylation ; GO:0046777 | inferred from direct assay negative regulation of neuron apoptotic process ; GO:0043524 | inferred from mutant phenotype stem cell proliferation ; GO:0072089 | inferred from direct assay regulation of cell proliferation ; GO:0042127 | inferred from mutant phenotype peptidyl-threonine phosphorylation ; GO:0018107 | inferred from direct assay regulation of protein processing ; GO:0070613 | inferred from direct assay intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator ; GO:0042771 | inferred from genetic interaction with p53 R8 cell fate specification ; GO:0045464 | inferred from mutant phenotype retinal cell programmed cell death ; GO:0046666 | inferred from mutant phenotype negative regulation of cell proliferation ; GO:0008285 | inferred from mutant phenotype activation of cysteine-type endopeptidase activity ; GO:0097202 | inferred from direct assay border follicle cell migration ; GO:0007298 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from direct assay positive regulation of apoptotic signaling pathway ; GO:2001235 | inferred from mutant phenotype hippo signaling ; GO:0035329 | traceable author statement morphogenesis of an epithelial sheet ; GO:0002011 | inferred from mutant phenotype response to ionizing radiation ; GO:0010212 | inferred from mutant phenotype organ growth ; GO:0035265 | inferred from direct assay eye development ; GO:0001654 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay negative regulation of glial cell proliferation ; GO:0060253 | inferred from mutant phenotype negative regulation of organ growth ; GO:0046621 | traceable author statement hippo signaling ; GO:0035329 | inferred from biological aspect of ancestor with PANTHER:PTN001220914" cytoplasm ; GO:0005737 | inferred from direct assay membrane ; GO:0016020 | inferred from direct assay "hpo, Hpo, MST, hipo, CG11228, Hippo, dMST, MST2, hippo" "IPR000719:Protein kinase domain, IPR011009:Protein kinase-like domain, IPR011524:SARAH domain, IPR017441:Protein kinase, ATP binding site, IPR024205:Mst1 SARAH domain" CG11228 27-Aug-18 DroID_v2018_08 Drer\stk3 "Scer\SSK2, Scer\MKK2, Scer\SPS1, Scer\SSK22, Scer\MKK1" "Cele\C01C4.3, Cele\strd-1, Cele\cst-2, Cele\cst-1" "Xtro\stk3, Xtro\stk4" "Mmus\Stk4, Mmus\Stk3" "Hsap\STK4, Hsap\STK3" larval stage | third instar imaginal disc

FBgn0002486 l(3)SG46 lethal (3) SG46 http://flybase.org/reports/FBgn0002486 - gene - - - "l(3)g21, l(3)SG46" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" "ventral thoracic disc,imaginal disc" FBgn0025871 B52::tra2 B52::tra2 http://flybase.org/reports/FBgn0025871 - engineered_fusion_gene - - - "TRA-2/dSRp55, B52::tra2" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035084 CG15861 - http://flybase.org/reports/FBgn0035084 protein_coding_gene - - - "CG15861, R5_2R:20832201..20832579" IPR000742:EGF-like domain CG15861 27-Aug-18 DroID_v2018_08 "Drer\megf6a, Drer\ccbe1, Drer\tnfaip6, Drer\dkk2, Drer\esm1, Drer\zgc:158328, Drer\dkk1a, Drer\scarf1, Drer\megf11, Drer\pear1, Drer\megf10, Drer\megf6b" - "Cele\Y34B4A.5, Cele\B0393.5, Cele\ZK1193.3, Cele\R09H10.5" "Xtro\tnfaip6, Xtro\megf11, Xtro\stab2" "Mmus\Megf11, Mmus\Scarf1, Mmus\Dkk2, Mmus\Esm1, Mmus\Megf10, Mmus\Egfem1, Mmus\Tnfaip6, Mmus\Megf6, Mmus\Pear1, Mmus\Dkk3, Mmus\Stab1" "Hsap\SCARF1, Hsap\MEGF6, Hsap\TNFAIP6, Hsap\PEAR1, Hsap\SCARF2, Hsap\MEGF11, Hsap\MEGF10, Hsap\DKK2" "viable,fertile" FBgn0014238 l(2)31Eu lethal (2) 31Eu http://flybase.org/reports/FBgn0014238 - gene - - - l(2)31Eu - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0022699 D19B D19B http://flybase.org/reports/FBgn0022699 - protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN001227002 DNA binding ; GO:0003677 | inferred from biological aspect of ancestor with PANTHER:PTN001227002" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from biological aspect of ancestor with PANTHER:PTN001227002" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001227002 "CG10270, D19B, d19b" "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG10270 27-Aug-18 DroID_v2018_08 "Drer\zgc:162948, Drer\zgc:174268, Drer\znf1004, Drer\znf770, Drer\znf341, Drer\znf668" - "Cele\sdz-12, Cele\zfp-2, Cele\sem-4, Cele\spr-4, Cele\Y37F4.6, Cele\egl-43, Cele\hinf-1, Cele\Y48G8AL.10, Cele\eor-1, Cele\Y55F3AM.14, Cele\M03D4.4, Cele\lin-13" "Xtro\znf668, Xtro\zbtb41" "Mmus\Zfp112, Mmus\Zfp341, Mmus\Zfp668" "Hsap\ZNF341, Hsap\ZNF668, Hsap\ZNF30, Hsap\ZNF852, Hsap\ZNF284, Hsap\ZNF221" viable FBgn0027553 NELF-B NELF-B http://flybase.org/reports/FBgn0027553 "FBgn0029956, FBgn0052721" protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with UniProtKB:P92204 negative regulation of transcription elongation from RNA polymerase II promoter ; GO:0034244 | inferred from direct assay negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter during mitosis ; GO:0007070 | inferred from sequence or structural similarity with UniProtKB:P92204 positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype transcriptional repressor complex ; GO:0017053 | inferred from sequence or structural similarity with UniProtKB:P92204 NELF complex ; GO:0032021 | inferred from physical interaction with TH1 nucleus ; GO:0005634 | inferred from direct assay "CG12152, BcDNA:GH10333, NELF-B, CG32721, NELF" IPR010405:Cofactor of BRCA1 CG32721 27-Aug-18 DroID_v2018_08 Drer\nelfb - - Xtro\nelfb Mmus\Nelfb Hsap\NELFB "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0010614 l(2)06250 lethal (2) 06250 http://flybase.org/reports/FBgn0010614 - gene - - - l(2)06250 - - 27-Aug-18 DroID_v2018_08 - - - - - - partially lethal - majority die FBgn0086040 snoRNA:Me28S-A3365 - http://flybase.org/reports/FBgn0086040 snoRNA_gene - - - "snoRNA:Me28S-A3365, Me28S-Am3365, CR34669" - CR34669 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001574 l(1)63 lethal (1) 63 http://flybase.org/reports/FBgn0001574 - gene - - - "tsl(1)63, l(1)63" - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive,heat sensitive,male sterile,lethal,male" "mesothoracic tarsal bristle,heat sensitive,mesothoracic tarsal bristle longitudinal row 8,mesothoracic tarsal bristle longitudinal row 1,spermatocyte,metatarsus" FBgn0023136 WppG White prepupal locus G http://flybase.org/reports/FBgn0023136 - gene - - - "35, WppG" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0010767 l(3)02094 lethal (3) 02094 http://flybase.org/reports/FBgn0010767 - gene mRNA binding ; GO:0003729 | inferred from sequence or structural similarity - nucleus ; GO:0005634 | inferred from sequence or structural similarity small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from sequence or structural similarity "l(3)02094, L(3)02094" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0086059 snoRNA:Me18S-C1280 - http://flybase.org/reports/FBgn0086059 snoRNA_gene - - - "snoRNA:Me18S-C1280, Me18S-Cm1280, CR34688" - CR34688 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036009 Or67a Odorant receptor 67a http://flybase.org/reports/FBgn0036009 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | inferred from direct assay odorant binding ; GO:0005549 | inferred from physical interaction with Orco detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from direct assay dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 integral component of membrane ; GO:0016021 | inferred from direct assay "67a, DOR84, 67B.1, CG12526, Or67a, DmOR67a" "IPR004117:Olfactory receptor, insect" CG12526 27-Aug-18 DroID_v2018_08 - - Cele\T11F8.1 - - - viable FBgn0003397 sho shovel http://flybase.org/reports/FBgn0003397 - gene - - - sho - - 27-Aug-18 DroID_v2018_08 - - - - - - viable wing FBgn0020576 anon-59Ci anon-59Ci http://flybase.org/reports/FBgn0020576 - gene - - - anon-59Ci - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267315 lncRNA:TS16 long noncoding RNA: testis-specific 16 http://flybase.org/reports/FBgn0267315 non_protein_coding_gene - - - "lncRNA:TS16, CR45751" - CR45751 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002684 mat(3)3 maternal lethal 3 http://flybase.org/reports/FBgn0002684 - gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mat(3)3 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,non-rescuable maternal effect,recessive,heat sensitive,some die during embryonic stage" "pole cell,heat sensitive,stage 5 embryo,dorsal,posterior,embryonic ventral nervous system" FBgn0038200 CG9920 - http://flybase.org/reports/FBgn0038200 protein_coding_gene metal ion binding ; GO:0046872 | inferred from biological aspect of ancestor with PANTHER:PTN000080668 unfolded protein binding ; GO:0051082 | inferred from biological aspect of ancestor with PANTHER:PTN000080668 chaperone binding ; GO:0051087 | inferred from biological aspect of ancestor with PANTHER:PTN000080668 chaperone mediated protein folding requiring cofactor ; GO:0051085 | inferred from biological aspect of ancestor with PANTHER:PTN000080668 response to unfolded protein ; GO:0006986 | inferred from biological aspect of ancestor with PANTHER:PTN000080668 mitochondrial matrix ; GO:0005759 | inferred from biological aspect of ancestor with PANTHER:PTN000080669 "CG9920, BEST:GH20473, anon-WO0140519.48" "IPR011032:GroES-like, IPR020818:GroES chaperonin family" CG9920 27-Aug-18 DroID_v2018_08 Drer\hspe1 Scer\HSP10 Cele\Y22D7AL.10 Xtro\hspe1 Mmus\Hspe1 Hsap\HSPE1 "viable,visible" trichogen cell FBgn0037014 CG13251 - http://flybase.org/reports/FBgn0037014 protein_coding_gene - - - CG13251 - CG13251 27-Aug-18 DroID_v2018_08 Drer\ccdc66 - - - Mmus\Ccdc66 Hsap\CCDC66 viable FBgn0001229 Hsp67Bc Heat shock gene 67Bc http://flybase.org/reports/FBgn0001229 - protein_coding_gene unfolded protein binding ; GO:0051082 | inferred from sequence model protein binding ; GO:0005515 | inferred from physical interaction with stv chaperone-mediated protein folding ; GO:0061077 | inferred from sequence model positive regulation of protein lipidation ; GO:1903061 | inferred from mutant phenotype regulation of autophagy ; GO:0010506 | inferred from mutant phenotype response to heat ; GO:0009408 | inferred from direct assay regulation of translational initiation by eIF2 alpha phosphorylation ; GO:0010998 | inferred from mutant phenotype Z disc ; GO:0030018 | colocalizes_with inferred from direct assay "Dmel18.0, Hsp67Bc, hsp67B, CG4190, Hspg3, gene3, gene 3, gene5, gene-3, Hsp-G3, small hsp locus 67B, HSP67Bc, Dm-HSP67Bc, HSPB8, HSP67, Hsp67BC, HSP67BC" "IPR001436:Alpha crystallin/Heat shock protein, IPR002068:Alpha crystallin/Hsp20 domain, IPR008978:HSP20-like chaperone, IPR031107:Small heat shock protein HSP20" CG4190 27-Aug-18 DroID_v2018_08 "Drer\hspb12, Drer\hspb6, Drer\hspb1, Drer\hspb7, Drer\hspb15, Drer\hspb11, Drer\hspb8, Drer\si:dkey-1k23.3, Drer\hspb2, Drer\hspb9, Drer\cryaba, Drer\hspb3, Drer\cryaa" - "Cele\sip-1, Cele\ZK1128.7, Cele\hsp-12.2, Cele\hsp-16.11, Cele\hsp-43, Cele\F08H9.3, Cele\hsp-16.2, Cele\hsp-16.49, Cele\Y55F3BR.6, Cele\hsp-16.1, Cele\hsp-17, Cele\hsp-12.3, Cele\hsp-12.6, Cele\F08H9.4, Cele\hsp-16.48, Cele\hsp-12.1, Cele\hsp-16.41" "Xtro\hsp30d, Xtro\hspb3, Xtro\hsp30e, Xtro\hspb1, Xtro\cryab, Xtro\cryaa, Xtro\uqcrh, Xtro\hspb8, Xtro\hspb6, Xtro\hspb2" "Mmus\Hspb1, Mmus\Hspb2, Mmus\Cryab, Mmus\Hspb6, Mmus\Hspb7, Mmus\Hspb9, Mmus\Hspb8, Mmus\Cryaa, Mmus\Hspb3" "Hsap\LOC102724652, Hsap\CRYAA, Hsap\HSPB6, Hsap\HSPB1, Hsap\CRYAB, Hsap\HSPB7, Hsap\HSPB8, Hsap\HSPB9, Hsap\HSPB2, Hsap\HSPB3" " larval stage--pupal stage , prepupal stage , embryonic stage | >= 7hr " "viable,fertile" FBgn0015818 Spx Spliceosomal protein on the X http://flybase.org/reports/FBgn0015818 - protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011 neurogenesis ; GO:0022008 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000005846 mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity" precatalytic spliceosome ; GO:0071011 | inferred from direct assay U2 snRNP ; GO:0005686 | inferred from sequence or structural similarity with SGD:S000005846 "CG3780, SPX, Spx, spx, SF3B4" "IPR000504:RNA recognition motif domain, IPR034159:SF3B4, RNA recognition motif 2, IPR034158:SF3B4, RNA recognition motif 1" CG3780 27-Aug-18 DroID_v2018_08 Drer\sf3b4 Scer\HSH49 "Cele\arp-6, Cele\sap-49" Xtro\sf3b4 Mmus\Sf3b4 Hsap\SF3B4 "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC18720 K -0.67781696 0.175211295 -0.166514163 -0.076534338 -1.865229689 -1.261625145 FBgn0277431 l(3)psg17 - http://flybase.org/reports/FBgn0277431 gene - - - "l(3)psg17, psg17" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260104 2L3191 - http://flybase.org/reports/FBgn0260104 gene - - - 2L3191 - - 27-Aug-18 DroID_v2018_08 - - - - - - "embryonic/larval dorsal trunk,somatic clone" FBgn0036063 CG6674 - http://flybase.org/reports/FBgn0036063 protein_coding_gene - - - CG6674 IPR029338:Tumour suppressing sub-chromosomal transferable candidate 4 CG6674 27-Aug-18 DroID_v2018_08 Drer\tssc4 - - Xtro\tssc4 Mmus\Tssc4 Hsap\TSSC4 viable FBgn0051946 tRNA:Arg-TCT-3-1 transfer RNA:Arginine-TCT 3-1 http://flybase.org/reports/FBgn0051946 tRNA_gene AGA codon-amino acid adaptor activity ; GO:0033447 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033447 cytosol ; GO:0005829 | inferred by curator from GO:0033447 "AE002638.trna12-ArgTCT, tRNA:R:TCT:AE002638-b, CR31946, chr2L.trna5-ArgTCT, tRNA-Arg-TCT-3-1, tRNA:Arg-TCT-3-1, tRNA:CR31946, AGA" - CR31946 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0010645 l(2)08014 lethal (2) 08014 http://flybase.org/reports/FBgn0010645 - gene - - - l(2)08014 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0259728 CG42382 - http://flybase.org/reports/FBgn0259728 protein_coding_gene metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR000571 - - "CG42382, CG8016" "IPR000571:Zinc finger, CCCH-type" CG42382 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-113e8.11, Drer\rad51d" - Cele\ccch-3 Xtro\rad51d Mmus\Rad51d - "viable,visible" mesothoracic tergum FBgn0035649 CG10483 - http://flybase.org/reports/FBgn0035649 protein_coding_gene - - integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR004342 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000081883 CG10483 "IPR004331:SPX domain, IPR004342:EXS, C-terminal" CG10483 27-Aug-18 DroID_v2018_08 "Drer\xpr1b, Drer\xpr1a" "Scer\SYG1, Scer\VTC3, Scer\VTC2, Scer\ERD1, Scer\VTC4" Cele\Y39A1A.22 Xtro\xpr1 Mmus\Xpr1 Hsap\XPR1 "viable,fertile" FBgn0034054 CG8366 - http://flybase.org/reports/FBgn0034054 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR011604 nuclease activity ; GO:0004518 | inferred from electronic annotation with InterPro:IPR011604 - - CG8366 "IPR011335:Restriction endonuclease type II-like, IPR011604:Exonuclease, phage-type/RecB, C-terminal, IPR019080:YqaJ viral recombinase" CG8366 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC07153 I 0.538364737 1.529012203 0.973629552 1.034407923 0.326281002 0.314302639 FBgn0040324 Ephrin Ephrin http://flybase.org/reports/FBgn0040324 protein_coding_gene ephrin receptor binding ; GO:0046875 | inferred from direct assay melanotic encapsulation of foreign target ; GO:0035011 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype mushroom body development ; GO:0016319 | inferred from mutant phenotype integral component of plasma membrane ; GO:0005887 | inferred from direct assay "CG1862, Ephrin, lincRNA.922, ephrin" "IPR001799:Ephrin receptor-binding domain, IPR008972:Cupredoxin, IPR031328:Ephrin" CG1862 27-Aug-18 DroID_v2018_08 "Drer\efnb2a, Drer\efnb2b, Drer\efna3a, Drer\LOC100332852, Drer\efnb3a, Drer\efna1b, Drer\efna3b, Drer\efna1a, Drer\efna5a, Drer\efna2a, Drer\efnb1, Drer\efnb3b, Drer\efna5b" - "Cele\vab-2, Cele\efn-2, Cele\efn-4, Cele\efn-3" "Xtro\efna1, Xtro\efnb2, Xtro\efna2, Xtro\efna3, Xtro\efnb1, Xtro\efna5" "Mmus\Efnb3, Mmus\Efna4, Mmus\Efna2, Mmus\Efna3, Mmus\Efna1, Mmus\Efnb1, Mmus\Efna5, Mmus\Efnb2" "Hsap\EFNA4, Hsap\EFNA3, Hsap\EFNA5, Hsap\EFNB1, Hsap\EFNA2, Hsap\EFNA1, Hsap\EFNB2, Hsap\EFNB3" " embryonic stage | stage 4-5 , embryonic stage | stage 13 , embryonic stage | late , embryonic stage | gastrula , " "

, ventral ectoderm && embryonic somatic muscle | ventral && embryonic central nervous system | restricted

, central nervous system | restricted

, mesoderm | restricted

, cell

" "neuroanatomy defective,somatic clone,viable,recessive,fertile,immune response defective,visible" "adult antennal lobe projection neuron,somatic clone,mushroom body alpha-lobe,presumptive embryonic/larval central nervous system,commissure,medial lobe of adult mushroom body,vertical lobe of adult mushroom body,eye,medulla neuropil,lobula,longitudinal connective,embryonic/larval neuron" FBgn0266215 asRNA:CR44910 - http://flybase.org/reports/FBgn0266215 non_protein_coding_gene - - - CR44910 - CR44910 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0020344 anon-51Ba anon-51Ba http://flybase.org/reports/FBgn0020344 - gene - - - "514, anon-51Ba" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0021938 l(2)k10816 lethal (2) k10816 http://flybase.org/reports/FBgn0021938 - gene - - - l(2)k10816 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0031041 CG12788 - http://flybase.org/reports/FBgn0031041 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG33066, CG12788, Dromel_CG12788_CG17767_FBtr0074_tim9b_mORF, PSTK" "IPR013641:Protein KTI12/L-seryl-tRNA(Sec) kinase, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG12788 27-Aug-18 DroID_v2018_08 Drer\LOC101884223 - Cele\pstk-1 Xtro\pstk "Mmus\Timm10b, Mmus\Pstk" "Hsap\TIMM10B, Hsap\PSTK" FBgn0015320 Ubc2 Ubiquitin conjugating enzyme 2 http://flybase.org/reports/FBgn0015320 FBgn0021893 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with SGD:S000000286 inferred from sequence or structural similarity with SGD:S000002466 inferred from genetic interaction with SGD:S000000286 inferred from genetic interaction with SGD:S000002466 lipid storage ; GO:0019915 | inferred from direct assay protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with SGD:S000002466 cellular_component ; GO:0005575 | no biological data available "UbcD2, CG6720, ubcD2, l(2)k13206, Ubc2" "IPR000608:Ubiquitin-conjugating enzyme E2, IPR016135:Ubiquitin-conjugating enzyme/RWD-like, IPR023313:Ubiquitin-conjugating enzyme, active site" CG6720 27-Aug-18 DroID_v2018_08 "Drer\ube2d2, Drer\ube2d1b, Drer\ube2na, Drer\ube2e2, Drer\ube2d4, Drer\ube2nb, Drer\ube2e1, Drer\ube2d1a, Drer\ube2d2l, Drer\ube2t, Drer\ube2e3, Drer\ube2d3" "Scer\PEX4, Scer\UBC13, Scer\UBC4, Scer\UBC5" Cele\let-70 "Xtro\ube2e1, Xtro\ube2d3, Xtro\ube2e3, Xtro\ube2e2, Xtro\ube2n, Xtro\ube2d1, Xtro\ube2d4" "Mmus\Ube2e1, Mmus\Ube2t, Mmus\Ube2dnl2, Mmus\Ube2n, Mmus\Ube2d3, Mmus\Ube2d2b, Mmus\Ube2d1, Mmus\Ube2e2, Mmus\Ube2d2a, Mmus\Ube2dnl1, Mmus\Ube2e3" "Hsap\UBE2D4, Hsap\UBE2E3, Hsap\UBE2T, Hsap\UBE2Q2L, Hsap\UBE2N, Hsap\UBE2E1, Hsap\UBE2D1, Hsap\UBE2D3, Hsap\UBE2NL, Hsap\UBE2E2, Hsap\UBE2D2" "lethal,recessive,neuroanatomy defective,somatic clone,visible,viable" "neuroblast,somatic clone,macrochaeta,scutellar bristle,tormogen cell,trichogen cell,ectopic,mesothoracic tergum" FBgn0025941 anon-89Bb anon-89Bb http://flybase.org/reports/FBgn0025941 - gene - - - "89B-ov3.5, anon-89Bb" - - 27-Aug-18 DroID_v2018_08 - - - - - - adult stage ovary

FBgn0062624 Mod(var)1126 Mod(var)1126 http://flybase.org/reports/FBgn0062624 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1126, Mod(var)1126" - - 27-Aug-18 DroID_v2018_08 - - - - - - "suppressor of variegation,recessive,dominant,non-enhancer of variegation,non-suppressor of variegation,partially lethal - majority die" FBgn0052196 CG32196 - http://flybase.org/reports/FBgn0052196 protein_coding_gene gamma-glutamylcyclotransferase activity ; GO:0003839 | inferred from electronic annotation with InterPro:IPR017939 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32196 "IPR017939:Gamma-glutamylcyclotransferase, IPR013024:Gamma-glutamyl cyclotransferase-like" CG32196 27-Aug-18 DroID_v2018_08 "Drer\ggctb, Drer\ggcta" - Cele\C44B7.7 Xtro\ggct Mmus\Ggct Hsap\GGCT FBgn0001139 gro groucho http://flybase.org/reports/FBgn0001139 "FBgn0019999, FBgn0020008, FBgn0023439, FBgn0043006, FBgn0043009, FBgn0062049" protein_coding_gene transcription factor binding ; GO:0008134 | inferred from physical interaction with dl transcription corepressor activity ; GO:0003714 | inferred from direct assay repressing transcription factor binding ; GO:0070491 | inferred from physical interaction with cic CRD domain binding ; GO:0071906 | inferred from physical interaction with UniProtKB:Q9UJU2 repressing transcription factor binding ; GO:0070491 | inferred from physical interaction with retn protein binding ; GO:0005515 | inferred from physical interaction with kni HMG box domain binding ; GO:0071837 | inferred from physical interaction with UniProtKB:Q9UJU2 repressing transcription factor binding ; GO:0070491 | inferred from genetic interaction with E(spl)m7-HLH repressing transcription factor binding ; GO:0070491 | inferred from physical interaction with hkb RNA polymerase II transcription corepressor activity ; GO:0001106 | inferred from genetic interaction with E(spl)m7-HLH transcription factor binding ; GO:0008134 | inferred from physical interaction with HGTX transcription factor binding ; GO:0008134 | inferred from mutant phenotype DNA binding ; GO:0003677 | NOT non-traceable author statement transcription corepressor activity ; GO:0003714 | non-traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with Myc protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P91943 inferred from physical interaction with UniProtKB:Q01196-1 inferred from physical interaction with UniProtKB:Q01196-2 inferred from physical interaction with UniProtKB:Q13761 transcription factor binding ; GO:0008134 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with h transcription factor binding ; GO:0008134 | inferred from physical interaction with h inferred from physical interaction with E(spl)m7-HLH protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P14003 transcription corepressor activity ; GO:0003714 | traceable author statement transcription corepressor activity ; GO:0003714 | inferred from physical interaction with h transcription factor binding ; GO:0008134 | inferred from physical interaction with so protein binding ; GO:0005515 | inferred from physical interaction with elB "regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype inferred from genetic interaction with kni dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | traceable author statement negative regulation of smoothened signaling pathway ; GO:0045879 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from physical interaction with h sex determination, primary response to X:A ratio ; GO:0007541 | traceable author statement negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from genetic interaction with Myc negative regulation of Wnt signaling pathway ; GO:0030178 | non-traceable author statement negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay lateral inhibition ; GO:0046331 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | traceable author statement negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from genetic interaction with h actin filament organization ; GO:0007015 | inferred from mutant phenotype negative regulation of canonical Wnt signaling pathway ; GO:0090090 | inferred from direct assay nervous system development ; GO:0007399 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR009146 protein complex ; GO:0043234 | inferred from physical interaction with Myc nucleus ; GO:0005634 | traceable author statement "CG8384, gro, Gro, E(spl)gro, dGro, dAES1, dAES2, BcDNA.LD33829, E(spl)[2], l(3)gro, m9, m9/10, m9-m10, m9/m10, E(spl)-WD, E(spl)m9/m10, m10, m9,m10, BEST:LD15161, BEST:GM01575, En-spl, BcDNA:LD33829, anon-WO0118547.385, Groucho, GRO, Grg/TLE, DGro, groucho" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain, IPR001680:WD40 repeat, IPR005617:Groucho/TLE, N-terminal Q-rich domain, IPR009146:Groucho/transducin-like enhancer, IPR019775:WD40 repeat, conserved site, IPR011042:Six-bladed beta-propeller, TolB-like" CG8384 27-Aug-18 DroID_v2018_08 "Drer\aes, Drer\tle3a, Drer\si:dkey-42p8.3, Drer\zgc:136336, Drer\tle3b, Drer\tle2, Drer\chico" Scer\TUP1 "Cele\wdr-5.3, Cele\eya-1, Cele\unc-37, Cele\wdr-48" "Xtro\tle1, Xtro\tle2, Xtro\tle4, Xtro\aes" "Mmus\Aes, Mmus\Tle4, Mmus\Tle2, Mmus\Tle6, Mmus\Tle1, Mmus\Gm21964, Mmus\Tle3" "Hsap\TLE6, Hsap\TLE4, Hsap\AES, Hsap\TLE1, Hsap\TLE3, Hsap\TLE2" " embryonic stage | 2-6 hr , adult stage | female , embryonic stage | early , embryonic stage , embryonic stage | stage <=11 " " central nervous system

, embryonic peripheral nervous system

,

ubiquitous " "lethal,recessive,embryonic/larval segmentation phenotype,maternal effect,neuroanatomy defective,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,lethal - all die before end of P-stage,some die during pharate adult stage,neurogenic phenotype,viable,wild-type,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority live,dominant,female sterile,partially,male sterile,somatic clone,partially lethal - majority die" "filzkorper,maternal effect,larval head,intermediate ventral neurectoderm,eye,eye photoreceptor cell & eye-antennal discey.PH,eye-antennal disc | late third instar larval stage,head capsule,embryonic/first instar larval cuticle,wing,wing vein L4,wing vein L5,wing margin,wing vein,leg,denticle belt,ocellus,adult head & microchaeta,wing vein L1,wing vein L2,wing vein L3,anterior compartment,dorsal/ventral compartment boundary,macrochaeta & head,macrochaeta & thorax,macrochaeta & abdominal tergite,microchaeta & head,microchaeta & thorax,microchaeta & abdominal tergite,frontal bristle,supernumerary,germline clone,photoreceptor cell,somatic clone,dendrite,sense organ & wing,microchaeta & scutum,macrochaeta & scutum,macrochaeta,ventral nerve cord primordium,ommatidium,embryonic gnathal segment,embryonic epidermis,chaeta,ectopic,mesothoracic tergum,microchaeta,scutellum,anterior postalar bristle,mesothoracic tergum & macrochaeta-C253,sensory mother cell" FBgn0004473 ant antennaless http://flybase.org/reports/FBgn0004473 - gene - - - ant - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive" antenna FBgn0032446 CG5780 - http://flybase.org/reports/FBgn0032446 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cilium assembly ; GO:0060271 | inferred from sequence or structural similarity with HGNC:29669 intraciliary retrograde transport ; GO:0035721 | inferred from sequence or structural similarity with HGNC:29669 intraciliary transport particle A ; GO:0030991 | inferred from sequence or structural similarity with HGNC:29669 "CG5780, IFT43" IPR029302:Intraflagellar transport protein 43 CG5780 27-Aug-18 DroID_v2018_08 Drer\ift43 - - Xtro\ift43 Mmus\Ift43 Hsap\IFT43 FBgn0001875 l(1)XN82a lethal (1) XN82a http://flybase.org/reports/FBgn0001875 - gene - - - l(1)XN82a - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0015314 Tahiti Tahiti http://flybase.org/reports/FBgn0015314 - region - - - Tahiti - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004380 Klp64D Kinesin-like protein at 64D http://flybase.org/reports/FBgn0004380 - protein_coding_gene "microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR001752 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001752, InterPro:IPR019821 ATPase activity ; GO:0016887 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity microtubule motor activity ; GO:0003777 | inferred from biological aspect of ancestor with PANTHER:PTN000648413" sensory perception of smell ; GO:0007608 | inferred from mutant phenotype anterograde axonal transport ; GO:0008089 | inferred from mutant phenotype non-motile cilium assembly ; GO:1905515 | inferred from mutant phenotype neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype positive regulation of Wnt signaling pathway ; GO:0030177 | inferred from genetic interaction with arm inferred from genetic interaction with dsh inferred from genetic interaction with wg inferred from physical interaction with arm inferred from physical interaction with dsh sensory perception of sound ; GO:0007605 | inferred from mutant phenotype microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity establishment or maintenance of microtubule cytoskeleton polarity ; GO:0030951 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype sperm axoneme assembly ; GO:0007288 | NOT inferred from mutant phenotype cell junction ; GO:0030054 | inferred from mutant phenotype kinesin complex ; GO:0005871 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 cilium ; GO:0005929 | inferred from direct assay early endosome ; GO:0005769 | inferred from direct assay adherens junction ; GO:0005912 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay kinesin complex ; GO:0005871 | inferred from sequence or structural similarity "Kif3A, klp64D, CG10642, DmKlp64D, KLP64D, KLP4, Klp4, Klp64D, KLP64Ddm, Klp 64D, KIF 3A, KIF3A, kif3A" "IPR001752:Kinesin motor domain, IPR019821:Kinesin motor domain, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG10642 27-Aug-18 DroID_v2018_08 "Drer\kif17, Drer\kif5bb, Drer\kif3b, Drer\kif11, Drer\kif3a, Drer\kif5ba, Drer\LOC100331925, Drer\kif5c, Drer\kif5ab, Drer\kif3cb" "Scer\SMY1, Scer\KIP1, Scer\CIN8, Scer\KIP3" "Cele\klp-20, Cele\osm-3, Cele\bmk-1, Cele\klp-11" "Xtro\kif5c, Xtro\kif3a, Xtro\kif3b, Xtro\kif5a, Xtro\kif3c, Xtro\kif5b" "Mmus\Kif5a, Mmus\Kif3a, Mmus\Kif5b, Mmus\Kif5c, Mmus\Kif11, Mmus\Kif3b, Mmus\Kif17, Mmus\Kif3c, Mmus\Gm1305" "Hsap\KIF3A, Hsap\KIF3C, Hsap\KIF5A, Hsap\KIF5C, Hsap\KIF11, Hsap\KIF3B, Hsap\KIF5B" " adult stage , adult stage | female " " head

, ovary

" "lethal,recessive,hypoactive,uncoordinated,neuroanatomy defective,neurophysiology defective,auditory perception defective,female,viable" "scolopidial cilium,Johnston's organ & scolopidial cilium,cilium & cell,sensillum basiconicum of antennal segment 3,sensillum trichodeum of antennal segment 3,cilium,Johnston organ,scolopidial cilium & Johnston's organ,axonelav.PLu" FBgn0266864 lncRNA:CR45325 - http://flybase.org/reports/FBgn0266864 non_protein_coding_gene - - - CR45325 - CR45325 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039461 CG5500 - http://flybase.org/reports/FBgn0039461 protein_coding_gene - - - CG5500 "IPR019180:Oxidoreductase-like, N-terminal" CG5500 27-Aug-18 DroID_v2018_08 Drer\oxld1 Scer\YPL107W Cele\C49A9.10 - Mmus\Oxld1 Hsap\OXLD1 "fertile,viable,partially lethal - majority die,some die during pupal stage" FBgn0001834 l(1)ts538 lethal (1) ts538 http://flybase.org/reports/FBgn0001834 - gene - - - l(1)ts538 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,heat sensitive" FBgn0011950 tRNA:Arg-TCG-3-3 transfer RNA:Arginine-TCG 3-3 http://flybase.org/reports/FBgn0011950 "FBgn0011947, FBgn0052619, FBgn0060080" tRNA_gene CGA codon-amino acid adaptor activity ; GO:0033431 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033431 cytosol ; GO:0005829 | inferred by curator from GO:0033431 "tRNA-Arg, tRNA[arg], AE002593.trna6-ArgTCG, tRNA:R1, tRNA:arg1, tRNA:R:TCG:AE002593-d, CR32619, tRNA:arg12Ec, chrX.trna10-ArgTCG, tRNA-Arg-TCG-3-3, tRNA:Arg-TCG-3-3, tRNA:R:12Ec, CGA" - CR32619 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267207 lncRNA:CR45647 - http://flybase.org/reports/FBgn0267207 non_protein_coding_gene - - - CR45647 - CR45647 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259519 GG01518 - http://flybase.org/reports/FBgn0259519 gene - - - GG01518 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0031883 Caper Caper http://flybase.org/reports/FBgn0031883 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR006509 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with Ras85D inferred from genetic interaction with rl positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from genetic interaction with Ras85D" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay nucleus ; GO:0005634 | inferred by curator from GO:0000381 nucleoplasm ; GO:0005654 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay "CC1.3, CAPER, HCC1, cg11266, CG11266, Caper, igru" "IPR000504:RNA recognition motif domain, IPR006509:Splicing factor, RBM39-like, IPR029123:Splicing factor RBM39, linker" CG11266 27-Aug-18 DroID_v2018_08 "Drer\rbm39b, Drer\lemd3, Drer\rbm39a" Scer\NOP13 Cele\Y55F3AM.3 "Xtro\rbm23, Xtro\rbm39, Xtro\lemd3" "Mmus\Lemd3, Mmus\Lemd2, Mmus\Rbm39" "Hsap\LEMD2, Hsap\RBM39, Hsap\RBM23, Hsap\LEMD3" "viable,visible" trichogen cell DRSC02137 EK 0.549039671 0.567433218 -0.139840001 1.841334739 -2.366422357 -1.697928933 FBgn0086071 snoRNA:Or-CD11b - http://flybase.org/reports/FBgn0086071 snoRNA_gene - - - "snoRNA:Or-CD11b, Or-cd11b, CR34700" - CR34700 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037448 CG15186 - http://flybase.org/reports/FBgn0037448 protein_coding_gene - - - CG15186 - CG15186 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065738 l(2)SH0531 lethal (2) SH0531 http://flybase.org/reports/FBgn0065738 gene - - - "l(2)SH0531, l(2)SH2 0531" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0014987 l(2)46Dc lethal (2) 46Dc http://flybase.org/reports/FBgn0014987 - gene - - - "IX, l(2)46Dc" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0051067 CG31067 - http://flybase.org/reports/FBgn0051067 protein_coding_gene - - - CG31067 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264278 Su(Mir)1E2-4 - http://flybase.org/reports/FBgn0264278 gene - - - Su(Mir)1E2-4 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085310 CG34281 - http://flybase.org/reports/FBgn0085310 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG34281, CG14328" - CG34281 27-Aug-18 DroID_v2018_08 - - - - Mmus\Krtap19-4 "Hsap\KRTAP19-1, Hsap\KRTAP19-3" viable FBgn0005521 l(2)37Fh lethal (2) 37Fh http://flybase.org/reports/FBgn0005521 - gene - - - "l(2)C188, l(2)37Fh" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0064180 htz hitzschlag http://flybase.org/reports/FBgn0064180 gene - - - htz - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0003241 rf roof wings http://flybase.org/reports/FBgn0003241 - gene - - - rf - - 27-Aug-18 DroID_v2018_08 - - - - - - wing FBgn0034490 CG9864 - http://flybase.org/reports/FBgn0034490 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 anion transport ; GO:0006820 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000910672 "CT27832, CG9864" "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG9864 27-Aug-18 DroID_v2018_08 "Drer\si:ch1073-513e17.1, Drer\slc17a8, Drer\ppt1, Drer\slc17a9a, Drer\slc17a6b, Drer\slc17a6a, Drer\slc17a5, Drer\slc17a7a" "Scer\YIL166C, Scer\DAL5, Scer\GAL2, Scer\TNA1, Scer\THI73" "Cele\R10D12.1, Cele\slc-17.4, Cele\C35A5.3, Cele\T27D12.1, Cele\T22F3.7, Cele\slc-17.3, Cele\slc-17.2, Cele\T22F3.11, Cele\K08C7.1, Cele\T19D12.9, Cele\T22F3.10, Cele\F10C2.7, Cele\C01B4.7, Cele\Y19D10A.8, Cele\slc-17.9, Cele\W04C9.6, Cele\Y19D10A.4, Cele\cima-1, Cele\F56A4.12, Cele\C39E9.7, Cele\Y51B9A.6, Cele\C18H9.5, Cele\T22F3.8, Cele\T01H3.3, Cele\slc-17.8, Cele\C18D1.2, Cele\slc-17.1, Cele\F56A4.10, Cele\H11E01.2, Cele\Y4C6B.4, Cele\K11G9.5, Cele\F11A5.9, Cele\F59A1.13, Cele\F47B8.10, Cele\F41C3.2, Cele\T28H11.8, Cele\M117.1, Cele\D1046.4, Cele\T19D12.10, Cele\Y15E3A.4, Cele\slc-17.6, Cele\slc-17.5, Cele\M162.5, Cele\Y4C6B.3, Cele\T02B11.6, Cele\slc-17.7, Cele\Y19D10A.5, Cele\F44E7.7, Cele\C01B4.8, Cele\Y19D10A.11" "Xtro\slc17a7, Xtro\slc22a5" "Mmus\Slc17a2, Mmus\Slc17a1, Mmus\Slc17a7, Mmus\Slc17a6, Mmus\Slc37a4, Mmus\Slc17a4, Mmus\Slc17a3, Mmus\Slc17a5, Mmus\Slc17a8, Mmus\Slc22a2" "Hsap\SLC17A1, Hsap\SLC17A8, Hsap\SLC17A2, Hsap\SLC37A4, Hsap\SLC17A4, Hsap\SLC17A3, Hsap\SLC17A6, Hsap\SLC17A7, Hsap\SLC17A5" viable FBgn0005199 l(3)ac lethal (3) accessory http://flybase.org/reports/FBgn0005199 - gene - - - l(3)ac - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0024530 l(3)L0499 lethal (3) L0499 http://flybase.org/reports/FBgn0024530 - gene - - - l(3)L0499 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0260382 GSd462 - http://flybase.org/reports/FBgn0260382 gene - - - GSd462 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve,segmental nerve" FBgn0038977 CG5376 - http://flybase.org/reports/FBgn0038977 protein_coding_gene - - - CG5376 - CG5376 27-Aug-18 DroID_v2018_08 - - - - - - viable "germline cell,male" FBgn0265347 lncRNA:CR44301 - http://flybase.org/reports/FBgn0265347 non_protein_coding_gene - - - CR44301 - CR44301 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0062685 EP1509 EP1509 http://flybase.org/reports/FBgn0062685 gene - - - "EP(X)1509, EP1509" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0082940 snoRNA:Me28S-C3227a snoRNA:Me28S-C3227a http://flybase.org/reports/FBgn0082940 snoRNA_gene - - - "snoRNA:Me28S-C3227a, Me28S-Cm3227a, Me28S-C3227a, CR34533" - CR34533 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0053802 His-Psi:CR33802 His-Psi:CR33802 http://flybase.org/reports/FBgn0053802 pseudogene_attribute - - - "CR33802, His-Psi:CR33802" - CR33802 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004598 Fur2 Furin 2 http://flybase.org/reports/FBgn0004598 FBgn0042227 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from genetic interaction with Fur1 serine-type endopeptidase activity ; GO:0004252 | inferred from direct assay "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000209, InterPro:IPR002884 negative regulation of secretion ; GO:0051048 | inferred from genetic interaction with pgant4 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype" plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with Fur1 "154521_at, fur2, Furin, Dfur2, FUR2, DMH#11, furin, CG4235, CG18734, Fur2, Dfurin2" "IPR000209:Peptidase S8/S53 domain, IPR002884:Proprotein convertase, P, IPR006212:Furin-like repeat, IPR008979:Galactose-binding domain-like, IPR009020:Protease propeptides/proteinase inhibitor I9, IPR009030:Growth factor receptor cysteine-rich domain, IPR015500:Peptidase S8, subtilisin-related, IPR032815:Peptidase S8, pro-domain, IPR032778:Growth factor receptor domain 4, IPR034182:Kexin/furin catalytic domain, IPR000494:Receptor L-domain, IPR000742:EGF-like domain, IPR022398:Peptidase S8, subtilisin, His-active site, IPR023827:Peptidase S8, subtilisin, Asp-active site, IPR023828:Peptidase S8, subtilisin, Ser-active site" CG18734 27-Aug-18 DroID_v2018_08 "Drer\pcsk7, Drer\pcsk5a, Drer\pcsk1, Drer\pcsk2, Drer\furinb, Drer\fras1, Drer\pcsk5b, Drer\LOC100330575, Drer\furina, Drer\rspo3" Scer\KEX2 "Cele\egl-3, Cele\aex-5, Cele\bli-4, Cele\kpc-1, Cele\F48E3.8" "Xtro\rspo3, Xtro\pcsk7, Xtro\pcsk5, Xtro\furin, Xtro\pcsk2, Xtro\pcsk6, Xtro\pcsk1, Xtro\fras1, Xtro\pcsk4" "Mmus\Pcsk1, Mmus\Pcsk5, Mmus\Rspo4, Mmus\Pcsk7, Mmus\Pcsk2, Mmus\Rspo3, Mmus\Rspo1, Mmus\Furin, Mmus\Fras1, Mmus\Pcsk4, Mmus\Pcsk6" "Hsap\PCSK4, Hsap\RSPO4, Hsap\PCSK1, Hsap\RSPO1, Hsap\FRAS1, Hsap\FURIN, Hsap\PCSK2, Hsap\PCSK6, Hsap\RSPO3, Hsap\PCSK5, Hsap\PCSK7" viable FBgn0038210 CG3199 - http://flybase.org/reports/FBgn0038210 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG3199 IPR031992:Domain of unknown function DUF4788 CG3199 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0265252 asRNA:CR44266 - http://flybase.org/reports/FBgn0265252 non_protein_coding_gene - - - CR44266 - CR44266 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0064165 l(3)Eq1 lethal (3) Eq1 http://flybase.org/reports/FBgn0064165 gene - - - l(3)Eq1 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0024887 kin17 kin17 http://flybase.org/reports/FBgn0024887 FBgn0036976 protein_coding_gene double-stranded DNA binding ; GO:0003690 | inferred from biological aspect of ancestor with PANTHER:PTN000301499 "DNA replication ; GO:0006260 | inferred from biological aspect of ancestor with PANTHER:PTN000301499 cellular response to DNA damage stimulus ; GO:0006974 | inferred from biological aspect of ancestor with PANTHER:PTN000301499 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011" precatalytic spliceosome ; GO:0071011 | inferred from direct assay "CG5649, kin17" "IPR019447:DNA/RNA-binding protein Kin17, conserved domain, IPR013087:Zinc finger C2H2-type" CG5649 27-Aug-18 DroID_v2018_08 Drer\kin Scer\RTS2 Cele\dxbp-1 Xtro\kin Mmus\Kin Hsap\KIN viable FBgn0030729 CG12507 - http://flybase.org/reports/FBgn0030729 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12507 - CG12507 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0060540 l(3)S100108a lethal (3) S100108a http://flybase.org/reports/FBgn0060540 gene - - - "1001/08, l(3)S100108a" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0284244 l(2)k05911 lethal (2) k05911 http://flybase.org/reports/FBgn0284244 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "l(2)k05911, SP36, c-SP36, CG16821, CG31728" "IPR022700:Proteinase, regulatory CLIP domain, IPR033116:Serine proteases, trypsin family, serine active site, IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site" CG31728 27-Aug-18 DroID_v2018_08 "Drer\ctrb1, Drer\si:ch211-165b19.8, Drer\si:dkey-78l4.13, Drer\tmprss5, Drer\f10, Drer\ela2l, Drer\ctrl, Drer\si:dkey-78l4.8, Drer\zgc:92511, Drer\plg, Drer\zgc:112302, Drer\zgc:112285, Drer\zgc:171592, Drer\zgc:154142, Drer\zgc:112160, Drer\ela3l, Drer\si:dkey-78l4.1, Drer\si:dkey-78l4.12, Drer\zgc:112368, Drer\zgc:92745, Drer\pik3ip1, Drer\si:dkey-78l4.2, Drer\ela2, Drer\f2, Drer\si:dkey-78l4.7, Drer\si:dkey-238d18.3, Drer\zgc:163025, Drer\zgc:92041, Drer\LOC562139, Drer\si:dkey-57c15.4, Drer\tmprss4b, Drer\proza, Drer\prozb, Drer\f9b, Drer\habp2, Drer\si:dkey-78l4.6, Drer\f9a, Drer\gzm3, Drer\si:dkey-33i11.3" - "Cele\try-9, Cele\try-1" "Xtro\LOC100135144, Xtro\cela3a, Xtro\LOC100489516, Xtro\LOC101733231, Xtro\ctrb1, Xtro\cela2a, Xtro\gzmh, Xtro\ctrb2" "Mmus\Gzme, Mmus\Cela3b, Mmus\Cela2a, Mmus\Ctrb1, Mmus\Cela3a, Mmus\Prss54, Mmus\Tmprss11b, Mmus\Ctrl, Mmus\Hpn, Mmus\Mcpt8, Mmus\Prss55, Mmus\Cela1, Mmus\Ctrc, Mmus\Pik3ip1" "Hsap\GZMM, Hsap\HPN, Hsap\CELA3A, Hsap\PRSS54, Hsap\CELA3B, Hsap\PIK3IP1, Hsap\CTRC, Hsap\PRSS57, Hsap\CMA1, Hsap\CTRL, Hsap\CELA1, Hsap\GZMA, Hsap\CELA2B, Hsap\CTSG, Hsap\CELA2A, Hsap\AZU1, Hsap\TPSD1, Hsap\PRSS55, Hsap\CTRB1, Hsap\TPSAB1, Hsap\CTRB2" FBgn0024858 l(3)96Bd lethal (3) 96Bd http://flybase.org/reports/FBgn0024858 - gene - - - l(3)96Bd - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0067100 H47 H47 http://flybase.org/reports/FBgn0067100 gene - - - H47 - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,eye color defective,lethal" "chaeta,ommatidium,pigment cell" FBgn0060795 l(3)S058407 lethal (3) S058407 http://flybase.org/reports/FBgn0060795 gene - - - "0584/07, l(3)S058407" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0267681 lncRNA:CR46017 - http://flybase.org/reports/FBgn0267681 non_protein_coding_gene - - - CR46017 - CR46017 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005439 l(1)v129 lethal (1) v129 http://flybase.org/reports/FBgn0005439 - gene - - - "l(1)129, l(1)v129" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034580 Cht8 Chitinase 8 http://flybase.org/reports/FBgn0034580 protein_coding_gene "hydrolase activity, hydrolyzing O-glycosyl compounds ; GO:0004553 | inferred from electronic annotation with InterPro:IPR001579 chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557" "chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR001223, InterPro:IPR001579, InterPro:IPR013781 ecdysis, chitin-based cuticle ; GO:0018990 | inferred from mutant phenotype" extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "Cht8, CG9357, DmCht8" "IPR001223:Glycoside hydrolase family 18, catalytic domain, IPR001579:Glycoside hydrolase, chitinase active site, IPR002557:Chitin binding domain, IPR011583:Chitinase II, IPR017853:Glycoside hydrolase superfamily, IPR029070:Chitinase insertion domain" CG9357 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-226m16.2, Drer\chia.1, Drer\chia.6, Drer\chia.3, Drer\srl, Drer\ovgp1, Drer\chia.2, Drer\chia.5" Scer\CTS2 "Cele\chil-24, Cele\cht-2, Cele\chil-16, Cele\cht-1, Cele\chil-3, Cele\chil-17, Cele\lmd-4, Cele\chil-5, Cele\chil-21, Cele\cht-4, Cele\chil-22, Cele\chil-20, Cele\lmd-5, Cele\chil-19, Cele\chil-7, Cele\chil-12, Cele\chil-6, Cele\chil-4, Cele\chil-13, Cele\chil-23, Cele\chil-25, Cele\cht-3, Cele\chil-9, Cele\chil-18, Cele\chil-15, Cele\chil-11, Cele\T19H5.6, Cele\chil-8, Cele\chil-1, Cele\chil-2" "Xtro\srl, Xtro\chit1, Xtro\ctbs, Xtro\chia, Xtro\LOC548945" "Mmus\Ovgp1, Mmus\Chit1, Mmus\Chil1, Mmus\Ctbs, Mmus\Chil4, Mmus\Chil5, Mmus\Chil3, Mmus\Srl, Mmus\Chil6, Mmus\Chia1" "Hsap\CHI3L1, Hsap\CHI3L2, Hsap\CHIA, Hsap\CHIT1, Hsap\SRL, Hsap\OVGP1" viable FBgn0002167 l(2)Sp9d lethal (2) Sp9d http://flybase.org/reports/FBgn0002167 - gene - - - l(2)Sp9d - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0264883 lncRNA:CR44074 - http://flybase.org/reports/FBgn0264883 non_protein_coding_gene - - - CR44074 - CR44074 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0029824 CG3726 - http://flybase.org/reports/FBgn0029824 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR007889, InterPro:IPR009057, InterPro:IPR017956" regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001135004 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001135004 CG3726 "IPR007889:DNA binding HTH domain, Psq-type, IPR000210:BTB/POZ domain, IPR011333:SKP1/BTB/POZ domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR009057:Homeobox domain-like" CG3726 27-Aug-18 DroID_v2018_08 - - - - "Mmus\Nacc1, Mmus\Nacc2" Hsap\ZBTB9 "viable,fertile,body color defective" mesothoracic tergum FBgn0264481 asRNA:CR43889 - http://flybase.org/reports/FBgn0264481 non_protein_coding_gene - - - CR43889 - CR43889 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085660 CG41500 - http://flybase.org/reports/FBgn0085660 protein_coding_gene - - - CG41500 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001437 l(1)7Be lethal (1) 7Be http://flybase.org/reports/FBgn0001437 - gene - - - "l(1)DC829, l(1)7Be" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0033744 Dh44-R2 Diuretic hormone 44 receptor 2 http://flybase.org/reports/FBgn0033744 protein_coding_gene "G-protein coupled receptor activity ; GO:0004930 | inferred from electronic annotation with InterPro:IPR000832, InterPro:IPR001879, InterPro:IPR017983 diuretic hormone receptor activity ; GO:0008036 | inferred from physical interaction with Dh44 neuropeptide receptor activity ; GO:0008188 | inferred from sequence model diuretic hormone receptor activity ; GO:0008036 | inferred from sequence or structural similarity calcitonin receptor activity ; GO:0004948 | inferred from sequence or structural similarity" cell surface receptor signaling pathway ; GO:0007166 | inferred from electronic annotation with InterPro:IPR017981 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from direct assay hormone-mediated signaling pathway ; GO:0009755 | inferred from direct assay G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model response to salt stress ; GO:0009651 | inferred from mutant phenotype G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model "CG13156, anon-WO0170980.104, anon-WO0170980.103, CG1315, CG12370, Dh44-R2, DH44-R2, DH-R, Dh44R2" "IPR000832:GPCR, family 2, secretin-like, IPR001879:GPCR, family 2, extracellular hormone receptor domain, IPR002001:GPCR, family 2, diuretic hormone receptor, IPR017981:GPCR, family 2-like, IPR017983:GPCR, family 2, secretin-like, conserved site" CG12370 27-Aug-18 DroID_v2018_08 "Drer\vipr1b, Drer\gipr, Drer\calcrl2, Drer\gcgra, Drer\pth1rb, Drer\calcr, Drer\calcrla, Drer\gcgrb, Drer\crhr2, Drer\calcrlb, Drer\pth2r, Drer\si:dkeyp-4h4.1, Drer\adcyap1r1b, Drer\ghrhrb, Drer\ghrhra, Drer\pth1ra, Drer\adcyap1r1a, Drer\crhr1, Drer\vipr2, Drer\ghrhr2, Drer\vipr1a" - "Cele\seb-3, Cele\pdfr-1" "Xtro\gcgr, Xtro\gipr, Xtro\vipr1, Xtro\crhr1.2, Xtro\pth2r, Xtro\pth1r, Xtro\adcyap1r1, Xtro\calcrl, Xtro\crhr1.1" "Mmus\Pth2r, Mmus\Crhr1, Mmus\Calcr, Mmus\Gipr, Mmus\Vipr2, Mmus\Crhr2, Mmus\Ghrhr, Mmus\Glp2r, Mmus\Glp1r, Mmus\Adcyap1r1, Mmus\Calcrl, Mmus\Pth1r, Mmus\Vipr1, Mmus\Sctr, Mmus\Gcgr" "Hsap\CALCRL, Hsap\GIPR, Hsap\VIPR1, Hsap\ADCYAP1R1, Hsap\GCGR, Hsap\GLP2R, Hsap\CALCR, Hsap\CRHR1-IT1-CRHR1, Hsap\GLP1R, Hsap\PTH1R, Hsap\GHRHR, Hsap\VIPR2, Hsap\SCTR, Hsap\CRHR1, Hsap\CRHR2, Hsap\PTH2R" "osmotic stress response defective,viable" FBgn0040801 CG13053 - http://flybase.org/reports/FBgn0040801 protein_coding_gene - - - CG13053 - CG13053 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" FBgn0040809 CG13465 - http://flybase.org/reports/FBgn0040809 protein_coding_gene - - - CG13465 - CG13465 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263911 COX8 Cytochrome c oxidase subunit 8 http://flybase.org/reports/FBgn0263911 protein_coding_gene cytochrome-c oxidase activity ; GO:0004129 | inferred from electronic annotation with InterPro:IPR003205 - - "CG7181, VIII, BcDNA:GH15688, anon-WO0118547.331, 0554/18, l(3)S055418, COX8, CoVIII, CcO VIIc" "IPR003205:Cytochrome c oxidase, subunit 8" CG7181 27-Aug-18 DroID_v2018_08 "Drer\cox8b, Drer\si:dkey-85n7.8, Drer\cox8a" - - - "Mmus\Cox8a, Mmus\Cox8c, Mmus\Cox8b" "Hsap\COX8A, Hsap\COX8C" DRSC11814 K -0.960265869 -1.106376939 -0.955817277 0.024078421 2.193120641 1.985592463 FBgn0033234 MFS12 Major Facilitator Superfamily Transporter 12 http://flybase.org/reports/FBgn0033234 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 anion transport ; GO:0006820 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000910672 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 "anon-WO0140519.99, CG8791, MFS12" "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG8791 27-Aug-18 DroID_v2018_08 "Drer\slc17a9a, Drer\si:ch1073-513e17.1, Drer\ppt1, Drer\slc17a6b, Drer\slc17a8, Drer\slc17a6a, Drer\slc17a7a, Drer\slc17a5" "Scer\THI73, Scer\VHT1, Scer\YIL166C, Scer\DAL5, Scer\FEN2, Scer\YCT1, Scer\TNA1" "Cele\T22F3.10, Cele\vglu-3, Cele\F56A4.12, Cele\C01B4.8, Cele\Y15E3A.4, Cele\Y19D10A.11, Cele\D1046.4, Cele\C18D1.2, Cele\T22F3.8, Cele\Y19D10A.5, Cele\eat-4, Cele\T27D12.1, Cele\F44E7.7, Cele\slc-17.2, Cele\K11G9.5, Cele\M162.5, Cele\W04C9.6, Cele\slc-17.8, Cele\Y4C6B.3, Cele\slc-17.9, Cele\F41C3.2, Cele\T19D12.9, Cele\T02B11.6, Cele\Y19D10A.8, Cele\Y19D10A.4, Cele\Y51B9A.6, Cele\H11E01.2, Cele\C35A5.3, Cele\F11A5.9, Cele\T28H11.8, Cele\F59A1.13, Cele\C18H9.5, Cele\F56A4.10, Cele\slc-17.3, Cele\cima-1, Cele\Y4C6B.4, Cele\C39E9.7, Cele\F10C2.7, Cele\M117.1, Cele\T01H3.3, Cele\slc-17.5, Cele\K08C7.1, Cele\T22F3.7, Cele\vglu-2, Cele\C01B4.7, Cele\T19D12.10, Cele\slc-17.1, Cele\R10D12.1, Cele\slc-17.4, Cele\T22F3.11" Xtro\slc17a7 "Mmus\Slc17a7, Mmus\Slc17a4, Mmus\Slc17a1, Mmus\Slc17a6, Mmus\Slc17a2, Mmus\Slc17a3, Mmus\Slc17a5, Mmus\Slc17a8" "Hsap\SLC17A4, Hsap\SLC17A8, Hsap\SLC17A5, Hsap\SLC17A2, Hsap\SLC17A6, Hsap\SLC17A7, Hsap\SLC17A1, Hsap\SLC17A3" "viable,fertile" FBgn0040919 CG15895 - http://flybase.org/reports/FBgn0040919 protein_coding_gene - - - CG15895 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036032 CG16711 - http://flybase.org/reports/FBgn0036032 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG16711 IPR015943:WD40/YVTN repeat-like-containing domain CG16711 27-Aug-18 DroID_v2018_08 Drer\brd4 - - - - - "partially lethal - majority die,some die during pupal stage" FBgn0069052 COM centre organisateur de mobilisation http://flybase.org/reports/FBgn0069052 gene - - - COM - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0003168 Pur-r Purine-resistant http://flybase.org/reports/FBgn0003168 - gene - - - "PurR, Pur-r" - - 27-Aug-18 DroID_v2018_08 - - - - - - chemical resistant FBgn0017363 l(3)89Bq lethal (3) 89Bq http://flybase.org/reports/FBgn0017363 - gene - - - "l(3)89Bo, l(3)89Bq" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0005149 l(2)G78 lethal (2) G78 http://flybase.org/reports/FBgn0005149 - gene - - - l(2)G78 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0034961 CG3163 - http://flybase.org/reports/FBgn0034961 protein_coding_gene - - - CG3163 IPR006578:MADF domain CG3163 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0033029 Not3 CCR4-NOT transcription complex subunit 3 http://flybase.org/reports/FBgn0033029 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8SY33 poly(A)-specific ribonuclease activity ; GO:0004535 | inferred from direct assay "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR007207, InterPro:IPR007282, InterPro:IPR012270 mRNA catabolic process ; GO:0006402 | inferred from direct assay neurogenesis ; GO:0022008 | inferred from mutant phenotype nuclear-transcribed mRNA poly(A) tail shortening ; GO:0000289 | inferred from mutant phenotype negative regulation of translation ; GO:0017148 | inferred from direct assay" "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR007207, InterPro:IPR007282, InterPro:IPR012270 CCR4-NOT complex ; GO:0030014 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay CCR4-NOT core complex ; GO:0030015 | inferred from biological aspect of ancestor with PANTHER:PTN000595684 cytoplasmic mRNA processing body ; GO:0000932 | inferred from biological aspect of ancestor with PANTHER:PTN000595684" "Not3, NOT3, CG8426, NOT3/5, l(2)NC136, CNOT3, NOT3.5, not3" "IPR007207:CCR4-Not complex component, Not N-terminal domain, IPR007282:NOT2/NOT3/NOT5, IPR012270:CCR4-NOT complex, subunit 3/ 5" CG8426 27-Aug-18 DroID_v2018_08 "Drer\cnot3a, Drer\cnot3b" "Scer\NOT3, Scer\NOT5" Cele\ntl-3 Xtro\cnot3 Mmus\Cnot3 Hsap\CNOT3 "lethal,recessive,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" DRSC04908 IE -0.439208659 -4.097402297 -2.378796068 -1.774960794 0.082698651 -0.643598999 FBgn0011971 tRNA:Ser-GCT-2-2 transfer RNA:Serine-GCT 2-2 http://flybase.org/reports/FBgn0011971 "FBgn0011968, FBgn0011969, FBgn0051476, FBgn0060055" tRNA_gene AGC codon-amino acid adaptor activity ; GO:0033446 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033446 cytosol ; GO:0005829 | inferred by curator from GO:0033446 "CR31476, tRNA[Ser][[2b]], AE002708.trna53-SerGCT, tRNA:S:GCT:AE002708-e, tRNA:ser, tRNA:S, tRNA:ser2b, tRNA:S2b, tRNA:ser2b:88A, tRNA[[Ser]], chr3R.trna59-SerGCT, tRNA-Ser-GCT-2-2, tRNA:Ser-GCT-2-2, tRNA:S2b:88A, AGC" - CR31476 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085829 CR42196 - http://flybase.org/reports/FBgn0085829 non_protein_coding_gene - - - CR42196 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001427 l(1)6Ed lethal (1) 6Ed http://flybase.org/reports/FBgn0001427 - gene - - - "l(1)jnL2, JNL2, jnL2, l(1)6Ed" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0036272 Sms - http://flybase.org/reports/FBgn0036272 protein_coding_gene spermine synthase activity ; GO:0016768 | inferred from biological aspect of ancestor with PANTHER:PTN000900684 spermine biosynthetic process ; GO:0006597 | inferred from biological aspect of ancestor with PANTHER:PTN000900684 cellular_component ; GO:0005575 | no biological data available "anon-WO0118547.387, CG4300" "IPR001045:Spermidine/spermine synthases, IPR030374:Polyamine biosynthesis domain, IPR015576:Spermine synthase, animal, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG4300 27-Aug-18 DroID_v2018_08 Drer\sms "Scer\SPE3, Scer\SPE4" Cele\spds-1 "Xtro\sms, Xtro\srm" "Mmus\Gm14680, Mmus\Srm, Mmus\Sms" "Hsap\SMS, Hsap\SRM" "viable,fertile" FBgn0030938 CG15047 - http://flybase.org/reports/FBgn0030938 protein_coding_gene - - - CG15047 "IPR015940:Ubiquitin-associated domain, IPR009060:UBA-like" CG15047 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,viable" FBgn0026659 l(2)17E1 lethal (2) 17E1 http://flybase.org/reports/FBgn0026659 - gene molecular_function ; GO:0003674 | no biological data available border follicle cell migration ; GO:0007298 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available l(2)17E1 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" "border follicle cell,somatic clone" FBgn0259590 B0756 - http://flybase.org/reports/FBgn0259590 gene - - - B0756 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "anterior crossvein,submarginal cell,wing vein" FBgn0027186 l(2)60A-F lethal (2) 60A-F http://flybase.org/reports/FBgn0027186 - gene - - - l(2)60A-F - - 27-Aug-18 DroID_v2018_08 - - - - - - "wild-type,lethal,recessive" FBgn0025343 anon-25Dd anon-25Dd http://flybase.org/reports/FBgn0025343 - gene double-stranded RNA binding ; GO:0003725 | inferred from direct assay - - "#6, anon-25Dd" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031574 TTLL4B - http://flybase.org/reports/FBgn0031574 protein_coding_gene - protein polyglutamylation ; GO:0018095 | inferred from electronic annotation with InterPro:IPR027748 neurogenesis ; GO:0022008 | inferred from mutant phenotype - CG3964 "IPR004344:Tubulin-tyrosine ligase/Tubulin polyglutamylase, IPR027748:Tubulin polyglutamylase TTLL-4" CG3964 27-Aug-18 DroID_v2018_08 "Drer\ttll5, Drer\ttll4" - "Cele\ttll-4, Cele\ttll-5" Xtro\ttll4 "Mmus\Ttll4, Mmus\Ttll5" "Hsap\TTLL4, Hsap\TTLL5" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0011147 l(1)Q223 lethal (1) Q223 http://flybase.org/reports/FBgn0011147 FBgn0010210 gene - - - l(1)Q223 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0277417 l(3)psg8 - http://flybase.org/reports/FBgn0277417 gene - - - "l(3)psg8, psg8" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0027348 bgm bubblegum http://flybase.org/reports/FBgn0027348 "FBgn0027881, FBgn0028908" protein_coding_gene long-chain fatty acid-CoA ligase activity ; GO:0004467 | inferred from sequence or structural similarity long-chain fatty acid-CoA ligase activity ; GO:0004467 | inferred from direct assay long-chain fatty acid-CoA ligase activity ; GO:0004467 | inferred from mutant phenotype response to endoplasmic reticulum stress ; GO:0034976 | inferred from mutant phenotype long-chain fatty acid metabolic process ; GO:0001676 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from expression pattern inferred from mutant phenotype locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype neuron cellular homeostasis ; GO:0070050 | inferred from mutant phenotype fatty acid metabolic process ; GO:0006631 | inferred from mutant phenotype - "CG4501, bgm, BG:DS01514.2, 2a9hom, BG:DS0514.2, Bgm" IPR000873:AMP-dependent synthetase/ligase CG4501 27-Aug-18 DroID_v2018_08 "Drer\acsl5, Drer\acsl1a, Drer\acsbg1, Drer\acsbg2, Drer\acsl1b, Drer\acsl4a, Drer\acsl4b, Drer\acsl2, Drer\acsl3b, Drer\acsl6" "Scer\FAA2, Scer\FAA3, Scer\FAA1, Scer\FAA4" "Cele\acs-18, Cele\acs-15, Cele\acs-5" "Xtro\acsl5, Xtro\acsbg1, Xtro\acsl1, Xtro\acsbg2, Xtro\acsl6, Xtro\acsl4" "Mmus\Acsl1, Mmus\Acsl4, Mmus\Acsl5, Mmus\Acsl3, Mmus\Acsbg1, Mmus\Acsl6, Mmus\Acsbg2, Mmus\1700061G19Rik" "Hsap\ACSL4, Hsap\ACSL5, Hsap\ACSBG1, Hsap\ACSL6, Hsap\ACSL1, Hsap\ACSL3, Hsap\ACSBG2" "viable,fertile,aging defective,recessive,visual behavior defective,lethal,partially lethal - majority die,visible" "optic lobe,lamina,retina & cell body,photoreceptor cell & axon,mesothoracic tergum" DRSC03495 IEK -2.103706258 -0.789295605 1.458442373 -3.034931862 1.596038381 1.65697295 FBgn0011586 e(r) enhancer of rudimentary http://flybase.org/reports/FBgn0011586 FBgn0030068 protein_coding_gene - cell cycle ; GO:0007049 | inferred from electronic annotation with InterPro:IPR000781 pyrimidine nucleotide biosynthetic process ; GO:0006221 | inferred from electronic annotation with InterPro:IPR000781 positive regulation of Notch signaling pathway ; GO:0045747 | inferred from genetic interaction with dx inferred from genetic interaction with N nucleus ; GO:0005634 | inferred from direct assay "CG1871, ER, e(r), ER_DROME" IPR000781:Enhancer of rudimentary CG1871 27-Aug-18 DroID_v2018_08 Drer\erh - "Cele\T21C9.4, Cele\F35G12.11" Xtro\erh Mmus\Erh Hsap\ERH " adult stage | female , adult stage | male " "viable,fertile,wild-type,partially lethal - majority live,visible" trichogen cell FBgn0020058 E(w[a])706 E(w[a])706 http://flybase.org/reports/FBgn0020058 - gene - - - "E706, E(w[a])706" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,eye color defective" pigment cell FBgn0262437 mir-274 mir-274 stem loop http://flybase.org/reports/FBgn0262437 miRNA_gene - - - "dme-mir-274, mir-274, miR-274, CR42996, CR33582, dme-miR-274" - CR42996 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible,lethal - all die before end of pupal stage,some die during pupal stage,lethal" "wing,eye" FBgn0016021 l(3)85Ak lethal (3) 85Ak http://flybase.org/reports/FBgn0016021 - gene - - - l(3)85Ak - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0043040 l(2)42Ba lethal (2) 42Ba http://flybase.org/reports/FBgn0043040 gene - - - l(2)42Ba - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0084840 l(3)S023901 l(3)S023901 http://flybase.org/reports/FBgn0084840 gene - - - l(3)S023901 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265152 lncRNA:CR44221 - http://flybase.org/reports/FBgn0265152 non_protein_coding_gene - - - CR44221 - CR44221 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263102 psq pipsqueak http://flybase.org/reports/FBgn0263102 protein_coding_gene protein homodimerization activity ; GO:0042803 | inferred from direct assay DNA binding ; GO:0003677 | traceable author statement sequence-specific DNA binding ; GO:0043565 | inferred from direct assay POZ domain binding ; GO:0031208 | inferred from direct assay DNA binding ; GO:0003677 | inferred from direct assay "regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001135004 olfactory behavior ; GO:0042048 | inferred from mutant phenotype chromatin silencing ; GO:0006342 | inferred from mutant phenotype anterior/posterior axis specification, embryo ; GO:0008595 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype gene silencing ; GO:0016458 | traceable author statement regulation of chromatin silencing ; GO:0031935 | inferred from mutant phenotype pole plasm assembly ; GO:0007315 | non-traceable author statement embryonic pattern specification ; GO:0009880 | inferred from mutant phenotype" nucleus ; GO:0005634 | traceable author statement PcG protein complex ; GO:0031519 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "PSQ, CG2368, psq, Psq, rum, eyeful, BTB-V, pip, psq-1, psk, zep, BtbV, Piq, Pipsqueak" "IPR011991:Winged helix-turn-helix DNA-binding domain, IPR011989:Armadillo-like helical, IPR015943:WD40/YVTN repeat-like-containing domain, IPR011333:SKP1/BTB/POZ domain, IPR000210:BTB/POZ domain, IPR007889:DNA binding HTH domain, Psq-type, IPR009057:Homeobox domain-like" CG2368 27-Aug-18 DroID_v2018_08 - - - - "Mmus\Nacc1, Mmus\Bach2, Mmus\Nacc2" Hsap\BACH2 " embryonic stage | 0-2 hr , embryonic stage | stage 5-8 , embryonic stage | late , larval stage | third instar , oogenesis stage , embryonic stage | stage 7-8 , embryonic stage | stage 5 " "

dorsal<&>anterior , maxillary segment

, photoreceptor cell R3 && photoreceptor cell R4

, eye-antennal disc | restricted

, ventral thoracic disc | restricted

, dorsal mesothoracic disc | restricted

, amnioserosa

, mandibular segment

, morphogenetic furrow | posterior to

, labial segment

,

20-70% egg length | dorsal " " adult stage && oogenesis stage | early , oogenesis stage | stage S10 && adult stage | female , larval stage " " germarium region 2a

, follicle cell

, eye-antennal disc | restricted

, dorsal mesothoracic disc

" FBgn0262903 lncRNA:CR43258 - http://flybase.org/reports/FBgn0262903 non_protein_coding_gene - - - "CR43258, lincRNA.813" - CR43258 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0250753 kra krasavietz http://flybase.org/reports/FBgn0250753 protein_coding_gene translation initiation factor binding ; GO:0031369 | inferred from physical interaction with eIF2β ribosome binding ; GO:0043022 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with shot protein binding ; GO:0005515 | inferred from physical interaction with RpL5 ribosomal small subunit binding ; GO:0043024 | inferred from direct assay long-term memory ; GO:0007616 | inferred from mutant phenotype axon midline choice point recognition ; GO:0016199 | inferred from mutant phenotype negative regulation of translation ; GO:0017148 | inferred from direct assay ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype positive regulation of filopodium assembly ; GO:0051491 | inferred from mutant phenotype inferred from genetic interaction with shot long-term memory ; GO:0007616 | traceable author statement oogenesis ; GO:0048477 | inferred from mutant phenotype axon ; GO:0030424 | inferred from direct assay filopodium ; GO:0030175 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay axonal growth cone ; GO:0044295 | inferred from direct assay "CG2922, Kra, ecp, eIF-5C, CT7240, elF-5C, Decp, l(3)03022, anon-WO0172774.49, eIf-5c, eIF, eiF-5C, l(3)j9B6, kra, eIF-5c, exba, eIF5c, Exba, elF5C, elf-5C, eIF5, ECP, chr3R:1423015..1423173, exba/kra, Ecp, 5MP" "IPR003307:W2 domain, IPR016024:Armadillo-type fold" CG2922 27-Aug-18 DroID_v2018_08 "Drer\bzw1b, Drer\bzw2, Drer\bzw1a" Scer\TIF5 Cele\C37C3.2 "Xtro\bzw2, Xtro\eif4g2, Xtro\bzw1" "Mmus\Bzw2, Mmus\Bzw1, Mmus\Eif5" "Hsap\BZW1, Hsap\EIF5, Hsap\BZW2" DRSC12320 IEK 0.332813796 -3.202455523 -1.511429492 1.449847694 -1.662290281 0.103800187 FBgn0036581 MED10 Mediator complex subunit 10 http://flybase.org/reports/FBgn0036581 protein_coding_gene RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from sequence or structural similarity RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from mutant phenotype protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VS38 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from electronic annotation with InterPro:IPR019145 transcription from RNA polymerase II promoter ; GO:0006366 | inferred from mutant phenotype negative regulation of neuroblast proliferation ; GO:0007406 | inferred from mutant phenotype transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity core mediator complex ; GO:0070847 | inferred from biological aspect of ancestor with PANTHER:PTN000331217 mediator complex ; GO:0016592 | inferred from sequence or structural similarity mediator complex ; GO:0016592 | inferred from direct assay "Med10, Nut2, CG5057, dTRAP15, dMED10, BcDNA:SD24044, MED10, med10, l(3)72Ds" "IPR019145:Mediator complex, subunit Med10" CG5057 27-Aug-18 DroID_v2018_08 Drer\med10 "Scer\NUT2, Scer\BUD27" Cele\mdt-10 Xtro\med10 Mmus\Med10 Hsap\MED10 "lethal - all die before end of pupal stage,some die during pupal stage" DRSC10474 EK -1.078593002 1.089935008 -2.440556108 -0.179582626 2.873923399 3.684931128 FBgn0016684 NaPi-T Na[+]-dependent inorganic phosphate cotransporter http://flybase.org/reports/FBgn0016684 - protein_coding_gene phosphate ion transmembrane transporter activity ; GO:0015114 | inferred from electronic annotation with InterPro:IPR004745 transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 phosphate ion transmembrane transport ; GO:0035435 | inferred from electronic annotation with InterPro:IPR004745 anion transport ; GO:0006820 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000910672 "Dropo, Na/Pi-cotransporter, CG10207, NaPi-T, NapiT, MFS2, Na[+]-dependent inorganic phosphate cotransporter" "IPR004745:Na-dependent inorganic phosphate cotransporter, IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG10207 27-Aug-18 DroID_v2018_08 "Drer\si:ch1073-513e17.1, Drer\slc17a5" "Scer\YIL166C, Scer\DAL5, Scer\THI73, Scer\TNA1" "Cele\T22F3.11, Cele\F56A4.12, Cele\Y51B9A.6, Cele\slc-17.9, Cele\Y19D10A.11, Cele\C18H9.5, Cele\D1046.4, Cele\slc-17.8, Cele\T02B11.6, Cele\Y4C6B.4, Cele\C18D1.2, Cele\C01B4.8, Cele\T28H11.8, Cele\M117.1, Cele\Y19D10A.4, Cele\F10C2.7, Cele\slc-17.6, Cele\F59A1.13, Cele\slc-17.3, Cele\C39E9.7, Cele\K08C7.1, Cele\slc-17.2, Cele\F56A4.10, Cele\M162.5, Cele\T19D12.10, Cele\F41C3.2, Cele\F44E7.7, Cele\K11G9.5, Cele\C01B4.7, Cele\R10D12.1, Cele\slc-17.4, Cele\T27D12.1, Cele\W04C9.6, Cele\Y15E3A.4, Cele\slc-17.1, Cele\slc-17.5, Cele\F11A5.9, Cele\T19D12.9, Cele\Y19D10A.5, Cele\slc-17.7, Cele\cima-1, Cele\T22F3.7, Cele\Y19D10A.8, Cele\T22F3.8, Cele\Y4C6B.3, Cele\H11E01.2, Cele\T01H3.3, Cele\T22F3.10, Cele\C35A5.3" - "Mmus\Slc17a1, Mmus\Slc17a3, Mmus\Slc17a4, Mmus\Slc17a2, Mmus\Slc17a5" "Hsap\SLC17A4, Hsap\SLC17A1, Hsap\SLC17A5, Hsap\SLC17A2, Hsap\SLC17A3" "viable,fertile" FBgn0030980 CG7406 - http://flybase.org/reports/FBgn0030980 protein_coding_gene - - - CG7406 IPR031903:Domain of unknown function DUF4766 CG7406 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264645 flash-flood flash flood http://flybase.org/reports/FBgn0264645 gene - trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype - flash-flood - - 27-Aug-18 DroID_v2018_08 - - - - - - "embryonic/larval lateral trunk,eye,somatic clone" FBgn0000073 Ama-2 alpha Amanitin-resistant 2 http://flybase.org/reports/FBgn0000073 - gene - - - Ama-2 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260577 MENE-X46 - http://flybase.org/reports/FBgn0260577 gene - - - MENE-X46 - - 27-Aug-18 DroID_v2018_08 - - - - - - "eye disc,somatic clone" FBgn0019745 l(1)83B lethal (1) 83B http://flybase.org/reports/FBgn0019745 - gene - - - l(1)83B - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0021847 l(2)k14710 lethal (2) k14710 http://flybase.org/reports/FBgn0021847 FBgn0027519 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype - "l(2)k15603, CG8325, BcDNA:LD21719, l(2)k14710" "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat" CG8325 27-Aug-18 DroID_v2018_08 "Drer\ttc7a, Drer\ttc7b, Drer\ttc34" - Cele\ttc-7 "Xtro\ttc7b, Xtro\ttc7a" "Mmus\Ttc7, Mmus\Ttc34, Mmus\Ttc7b" "Hsap\TTC7A, Hsap\TTC7B, Hsap\TTC34" "lethal,recessive,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0058362 CG40362 - http://flybase.org/reports/FBgn0058362 protein_coding_gene - - - CG40362 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051583 tRNA:Asn-GTT-1-10 transfer RNA:Asparagine-GTT 1-10 http://flybase.org/reports/FBgn0051583 tRNA_gene AAC codon-amino acid adaptor activity ; GO:0033442 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033442 cytosol ; GO:0005829 | inferred by curator from GO:0033442 "AE002708.trna67-AsnGTT, tRNA:asn5:84Fc, tRNA:N5:84Fc, tRNA:asn5:84Fb, tRNA:N5:84Fb, tRNA:asn5:84Fa, tRNA:N5:84Fa, tRNA:N:GTT:AE002708, CR31583, chr3R.trna73-AsnGTT, tRNA:Asn-GTT-1-10, tRNA:N5:84F, tRNA-Asn-GTT-1-10, AAC" - CR31583 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264942 lncRNA:CR44111 - http://flybase.org/reports/FBgn0264942 non_protein_coding_gene - - - CR44111 - CR44111 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263957 BG01121 - http://flybase.org/reports/FBgn0263957 gene - - - BG01121 - - 27-Aug-18 DroID_v2018_08 - - - - - - "long lived,male limited,starvation stress response defective,temperature response defective,gravitaxis defective,female limited" FBgn0039150 CG13605 - http://flybase.org/reports/FBgn0039150 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13605 "IPR001841:Zinc finger, RING-type, IPR017907:Zinc finger, RING-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG13605 27-Aug-18 DroID_v2018_08 "Drer\chfr, Drer\rnft1, Drer\rnf145b, Drer\rnf145a, Drer\syvn1, Drer\zmp:0000000662, Drer\amfr, Drer\rnft2, Drer\rnf151" "Scer\HRD1, Scer\SAN1" Cele\ZC13.1 "Xtro\chfr, Xtro\rnft2, Xtro\rnf139, Xtro\amfr, Xtro\rnft1, Xtro\LOC100127651, Xtro\rnf145, Xtro\syvn1" "Mmus\Trim69, Mmus\Amfr, Mmus\Chfr, Mmus\Rnf151, Mmus\Rnf145, Mmus\Rnft2, Mmus\Rnf139, Mmus\Rnft1, Mmus\Syvn1" "Hsap\RNFT1, Hsap\TRIM69, Hsap\SYVN1, Hsap\CHFR, Hsap\RNF151, Hsap\RNF145, Hsap\RNFT2, Hsap\AMFR, Hsap\RNF139" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0260461 Rcd7 Reduction in Cnn dots 7 http://flybase.org/reports/FBgn0260461 protein_coding_gene - centrosome separation ; GO:0051299 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype - "Rcd7, CG14098" - CG14098 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,viable" FBgn0014073 Tie Tie-like receptor tyrosine kinase http://flybase.org/reports/FBgn0014073 - protein_coding_gene "protein tyrosine kinase activity ; GO:0004713 | inferred from electronic annotation with InterPro:IPR020635 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 protein tyrosine kinase activity ; GO:0004713 | non-traceable author statement protein tyrosine kinase activity ; GO:0004713 | inferred from sequence or structural similarity" protein phosphorylation ; GO:0006468 | non-traceable author statement peptidyl-tyrosine phosphorylation ; GO:0018108 | inferred from sequence or structural similarity with HGNC:11724 border follicle cell migration ; GO:0007298 | inferred from genetic interaction with Egfr inferred from genetic interaction with Pvr negative regulation of cell death ; GO:0060548 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity transmembrane receptor protein tyrosine kinase signaling pathway ; GO:0007169 | inferred from sequence or structural similarity with HGNC:11724 regulation of cellular response to X-ray ; GO:2000683 | inferred from mutant phenotype integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity with HGNC:11724 "tie, RTK, CG7525, DPR1, Tie" "IPR000719:Protein kinase domain, IPR008266:Tyrosine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR020635:Tyrosine-protein kinase, catalytic domain, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain" CG7525 27-Aug-18 DroID_v2018_08 "Drer\fgfr1a, Drer\si:ch73-206d17.1, Drer\tek, Drer\fgfr2, Drer\mylk4a, Drer\flt1, Drer\csf1ra, Drer\mertka, Drer\fgfr3, Drer\tie1, Drer\kdrl, Drer\pdgfrl, Drer\si:dkey-14o18.6, Drer\ret, Drer\kita, Drer\mylkb, Drer\flt4, Drer\pdgfrb, Drer\csf1rb, Drer\LOC569566, Drer\kdr, Drer\mylk5, Drer\si:ch211-167j9.5, Drer\tyro3, Drer\pdgfra, Drer\kitb, Drer\fgfrl1a, Drer\flt3, Drer\fgfr4, Drer\styk1, Drer\fgfrl1b" - "Cele\Y38H6C.20, Cele\T25B9.4" "Xtro\fgfrl1, Xtro\pdgfrl, Xtro\styk1, Xtro\csf1r, Xtro\fgfr1, Xtro\tie1, Xtro\flt1, Xtro\tek, Xtro\kdr, Xtro\fgfr4, Xtro\ret, Xtro\pdgfrl.2, Xtro\pdgfra, Xtro\fgfr2, Xtro\flt4, Xtro\fgfr3" "Mmus\Kdr, Mmus\Ret, Mmus\Flt1, Mmus\Fgfr2, Mmus\Fgfr1, Mmus\Flt4, Mmus\Pdgfrb, Mmus\Pdgfra, Mmus\Tyro3, Mmus\Lmtk3, Mmus\Flt3, Mmus\Tie1, Mmus\Tek, Mmus\Styk1, Mmus\Fgfrl1, Mmus\Pdgfrl, Mmus\Kit, Mmus\Mertk, Mmus\Csf1r, Mmus\Fgfr3, Mmus\Fgfr4, Mmus\Axl" "Hsap\FGFR2, Hsap\FLT4, Hsap\FLT1, Hsap\TYRO3, Hsap\FLT3, Hsap\RET, Hsap\AXL, Hsap\PDGFRA, Hsap\KDR, Hsap\PDGFRB, Hsap\KIT, Hsap\TIE1, Hsap\TEK, Hsap\CSF1R, Hsap\FGFR4, Hsap\MERTK, Hsap\LMTK3, Hsap\PDGFRL, Hsap\STYK1, Hsap\FGFR1, Hsap\FGFR3, Hsap\FGFRL1" "viable,radiation sensitive,dominant" DRSC08702 I 1.634500123 0.021945634 1.240433087 -0.259324327 -0.153639017 -0.926267686 FBgn0260484 HIP Hsc/Hsp70-interacting protein http://flybase.org/reports/FBgn0260484 protein_coding_gene protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR034649 heat shock protein binding ; GO:0031072 | inferred from sequence or structural similarity with UniProtKB:P50503 Hsp70 protein binding ; GO:0030544 | inferred from sequence or structural similarity with UniProtKB:P50503 chaperone binding ; GO:0051087 | inferred from sequence or structural similarity with UniProtKB:P50503 chaperone cofactor-dependent protein refolding ; GO:0070389 | inferred from sequence or structural similarity with UniProtKB:P50503 protein complex ; GO:0043234 | inferred from sequence or structural similarity with UniProtKB:P50503 cytoplasm ; GO:0005737 | inferred from direct assay cytosol ; GO:0005829 | inferred from sequence or structural similarity with UniProtKB:P50503 "anon-EST:fe1A9, HIP, CG32789" "IPR011990:Tetratricopeptide-like helical domain, IPR006636:Heat shock chaperonin-binding, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat, IPR034649:Hsp70-interacting protein, N-terminal" CG32789 27-Aug-18 DroID_v2018_08 Drer\st13 Scer\SGT1 Cele\hip-1 Xtro\st13 "Mmus\St13, Mmus\Ppp5c" Hsap\ST13 FBgn0065953 l(2)SH0067 lethal (2) SH0067 http://flybase.org/reports/FBgn0065953 gene - - - "l(2)SH0067, l(2)SH2 0067" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0004818 fs(2)ltoDC37 female sterile (2) ltoDC37 http://flybase.org/reports/FBgn0004818 - gene molecular_function ; GO:0003674 | no biological data available ovarian nurse cell to oocyte transport ; GO:0007300 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(2)ltoDC37 - - 27-Aug-18 DroID_v2018_08 - - - - - - female sterile FBgn0013769 CypB Cyclophylin B http://flybase.org/reports/FBgn0013769 - gene - - - "DCyp-B, CypB" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040551 CG11686 - http://flybase.org/reports/FBgn0040551 protein_coding_gene - - - "BcDNA:RH19248, CG11686" - CG11686 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0065170 l(3)SH026 lethal (3) SH026 http://flybase.org/reports/FBgn0065170 gene - - - "l(3)SH026, l(2)SH3 026" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0263051 CG43346 - http://flybase.org/reports/FBgn0263051 protein_coding_gene NADH dehydrogenase (ubiquinone) activity ; GO:0008137 | inferred from electronic annotation with InterPro:IPR007763 electron carrier activity ; GO:0009055 | inferred from electronic annotation with InterPro:IPR007763 molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR007763 cellular_component ; GO:0005575 | no biological data available "CG43346, CG9243" IPR007763:NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 CG43346 27-Aug-18 DroID_v2018_08 "Drer\si:dkeyp-110e4.6, Drer\ndufaf2, Drer\pld3, Drer\si:ch211-194e18.2" - "Cele\F09G2.8, Cele\Y116A8C.30, Cele\E04F6.4" Xtro\pld3 "Mmus\Pld4, Mmus\Pld3, Mmus\Ndufaf2, Mmus\Pld5" "Hsap\PLD3, Hsap\PLD5, Hsap\PLD4, Hsap\NDUFAF2" embryonic/larval hemocyte | third instar larval stage FBgn0000771 fs(1)A1140 female sterile (1) A1140 http://flybase.org/reports/FBgn0000771 - gene - - - "fs(1)1140, fs(1)A1140" - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive,mitotic cell cycle defective,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage" "blastoderm embryo,gastrula embryo" FBgn0265069 lncRNA:CR44180 - http://flybase.org/reports/FBgn0265069 non_protein_coding_gene - - - CR44180 - CR44180 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035210 msd5 mitotic spindle density 5 http://flybase.org/reports/FBgn0035210 protein_coding_gene - mitotic spindle assembly ; GO:0090307 | inferred from mutant phenotype mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype HAUS complex ; GO:0070652 | colocalizes_with inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay "msd5, CG2213, Dgt7" - CG2213 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible" trichogen cell FBgn0037102 CRIF CR6-interacting factor http://flybase.org/reports/FBgn0037102 protein_coding_gene - cell cycle ; GO:0007049 | inferred from electronic annotation with InterPro:IPR018472 positive regulation of production of siRNA involved in RNA interference ; GO:1903705 | inferred from mutant phenotype cellular response to virus ; GO:0098586 | inferred from mutant phenotype positive regulation of RNA interference ; GO:1900370 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR018472 perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay "CG7172, anon-WO0118547.316, CRIF, dCRIF" IPR018472:Growth arrest/ DNA-damage-inducible protein-interacting protein 1 CG7172 27-Aug-18 DroID_v2018_08 Drer\gadd45gip1 - Cele\K07A1.10 Xtro\gadd45gip1 Mmus\Gadd45gip1 Hsap\GADD45GIP1 "viable,visible" trichogen cell FBgn0001933 l(2)25Ef lethal (2) 25Ef http://flybase.org/reports/FBgn0001933 - gene - - - "jf30, l(2)gdh-10, l(2)jf30, l(2)gdh10, l(2)25Ef" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0029093 cathD cathD http://flybase.org/reports/FBgn0029093 protein_coding_gene aspartic-type endopeptidase activity ; GO:0004190 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 autophagic cell death ; GO:0048102 | inferred from expression pattern salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern apoptotic process ; GO:0006915 | inferred from mutant phenotype nurse cell apoptotic process ; GO:0045476 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype protein catabolic process ; GO:0030163 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 lysosome ; GO:0005764 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay "CG1548, CT3996, CATH, T17, cathD, CathD, CTSD" "IPR001461:Aspartic peptidase A1 family, IPR001969:Aspartic peptidase, active site, IPR012848:Aspartic peptidase, N-terminal, IPR033144:Cathepsin D, IPR021109:Aspartic peptidase domain, IPR033121:Peptidase family A1 domain" CG1548 27-Aug-18 DroID_v2018_08 "Drer\ren, Drer\ctsd, Drer\zgc:63831, Drer\zgc:103530, Drer\nots" "Scer\YPS5, Scer\BAR1, Scer\YPS7, Scer\YPS3, Scer\MKC7, Scer\YPS1, Scer\YGL258W-A, Scer\YPS6, Scer\PEP4" "Cele\asp-16, Cele\asp-18, Cele\asp-19, Cele\asp-15, Cele\asp-14, Cele\asp-4, Cele\asp-13, Cele\asp-1, Cele\asp-2, Cele\asp-5, Cele\asp-6, Cele\asp-12, Cele\asp-9, Cele\asp-3, Cele\asp-10, Cele\asp-8, Cele\asp-17, Cele\asp-7" "Xtro\napsa, Xtro\pgc, Xtro\LOC100489529, Xtro\bace1, Xtro\ren, Xtro\LOC496913, Xtro\pga4, Xtro\bace2, Xtro\LOC613063, Xtro\LOC101735147, Xtro\ctse, Xtro\ctsd" "Mmus\Ren2, Mmus\Pgc, Mmus\Cym, Mmus\Napsa, Mmus\Bace2, Mmus\Ctsd, Mmus\Ctse, Mmus\Pga5, Mmus\Ren1, Mmus\Bace1" "Hsap\REN, Hsap\CTSE, Hsap\PGC, Hsap\BACE1, Hsap\PGA3, Hsap\PGA5, Hsap\BACE2, Hsap\NAPSA, Hsap\CTSD, Hsap\PGA4" "viable,fertile,increased cell death,conditional,cell death defective,decreased cell death" "adult brain,conditional,egg chamber,nurse cell,eye,spermatogonial cyst,male germline cell" FBgn0027147 l(3)71CDc lethal (3) 71CDc http://flybase.org/reports/FBgn0027147 - gene - - - l(3)71CDc - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0060349 l(3)S142215b lethal (3) S142215b http://flybase.org/reports/FBgn0060349 gene - - - "1422/15, l(3)S142215b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0038738 CG4572 - http://flybase.org/reports/FBgn0038738 protein_coding_gene serine-type carboxypeptidase activity ; GO:0004185 | inferred from biological aspect of ancestor with PANTHER:PTN000210642 dsRNA transport ; GO:0033227 | inferred from mutant phenotype proteolysis involved in cellular protein catabolic process ; GO:0051603 | inferred from biological aspect of ancestor with PANTHER:PTN000210642 - "CT14806, anon-WO02059370.13, CG4572" "IPR001563:Peptidase S10, serine carboxypeptidase, IPR018202:Serine carboxypeptidase, serine active site, IPR029058:Alpha/Beta hydrolase fold, IPR033124:Serine carboxypeptidases, histidine active site" CG4572 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-122f10.4, Drer\cpvl" "Scer\PRC1, Scer\YBR139W, Scer\KEX1" "Cele\K10C2.1, Cele\Y32F6A.5, Cele\C08H9.1, Cele\ctsa-2, Cele\F32A5.3, Cele\ctsa-1, Cele\Y16B4A.2, Cele\F41C3.5, Cele\F13D12.6" "Xtro\cpvl, Xtro\ctsa" "Mmus\Ctsa, Mmus\Scpep1, Mmus\Cpvl" "Hsap\SCPEP1, Hsap\CTSA, Hsap\CPVL" "viable,fertile" FBgn0015826 T-C9.12 T-C9.12 http://flybase.org/reports/FBgn0015826 - gene - - - T-C9.12 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259957 CG42467 - http://flybase.org/reports/FBgn0259957 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 - - CG42467 IPR002223:Pancreatic trypsin inhibitor Kunitz domain CG42467 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0011482 l(3)neo49 lethal (3) neo49 http://flybase.org/reports/FBgn0011482 - gene - - - l(3)neo49 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0082611 aact anti-activin http://flybase.org/reports/FBgn0082611 gene - - - "AACT, aact" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265556 12.95 - http://flybase.org/reports/FBgn0265556 gene - - - 12.95 - - 27-Aug-18 DroID_v2018_08 - - - - - - learning defective FBgn0004018 wo white ocelli http://flybase.org/reports/FBgn0004018 - gene - - - wo - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive" ocellus pigment granule FBgn0002327 l(3)86Ff lethal (3) 86Ff http://flybase.org/reports/FBgn0002327 - gene - - - "l(3)S063512, ck6, l(3)ck6, l(3)86Ff" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0259639 B1211 - http://flybase.org/reports/FBgn0259639 gene - - - B1211 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "tarsal segment,unguis" FBgn0016732 SR3-2 Suppressor of Ras85D 3-2 http://flybase.org/reports/FBgn0016732 - gene - - - SR3-2 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0039435 TwdlP TweedleP http://flybase.org/reports/FBgn0039435 protein_coding_gene structural constituent of chitin-based cuticle ; GO:0005214 | inferred from sequence or structural similarity with TwdlD body morphogenesis ; GO:0010171 | inferred from sequence or structural similarity with TwdlD chitin-based cuticle development ; GO:0040003 | inferred from sequence or structural similarity with TwdlD proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity with TwdlD "TwdlP, CG14240" IPR004145:Domain of unknown function DUF243 CG14240 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage,viable" DRSC14734 I 1.976514686 0.081340687 0.619697568 -0.452202267 0.144693257 0.745605585 FBgn0036131 CG12522 - http://flybase.org/reports/FBgn0036131 protein_coding_gene - - - CG12522 - CG12522 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC09088 I 1.932882938 0.456025944 -1.08514863 0.028996724 0.287038533 0.108066761 FBgn0058337 CG40337 - http://flybase.org/reports/FBgn0058337 protein_coding_gene - - - CG40337 - - 27-Aug-18 DroID_v2018_08 - - - - - - DRSC20701 IE -1.561639011 -0.99108678 -0.683278749 3.12587321 -0.243989747 -0.154654799 FBgn0014075 Uggt UDP-glucose-glycoprotein glucosyltransferase http://flybase.org/reports/FBgn0014075 "FBgn0046358, FBgn0046359" protein_coding_gene UDP-glucose:glycoprotein glucosyltransferase activity ; GO:0003980 | inferred from direct assay protein glycosylation ; GO:0006486 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from direct assay cytoplasm ; GO:0005737 | traceable author statement rough endoplasmic reticulum ; GO:0005791 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay nuclear envelope ; GO:0005635 | inferred from direct assay "GT, UGT, DUGT, CG6850, anon-WO0172774.75, anon-WO0172774.73, Ugt, UGGT, ugt" "IPR009448:UDP-glucose:Glycoprotein Glucosyltransferase, IPR029044:Nucleotide-diphospho-sugar transferases, IPR002495:Glycosyl transferase, family 8" CG6850 27-Aug-18 DroID_v2018_08 "Drer\uggt1, Drer\uggt2" Scer\KRE5 "Cele\uggt-2, Cele\uggt-1" "Xtro\uggt2, Xtro\uggt1" "Mmus\Uggt1, Mmus\Uggt2" "Hsap\UGGT1, Hsap\UGGT2" " embryonic stage--pupal stage , embryonic stage "

ubiquitous " embryonic stage -- adult stage , adult stage && oogenesis stage " oocyte

viable FBgn0039739 RpS28a Ribosomal protein S28a http://flybase.org/reports/FBgn0039739 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with SGD:S000005693 RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000080571 structural constituent of ribosome ; GO:0003735 | traceable author statement translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR000289 ribosomal small subunit assembly ; GO:0000028 | inferred from biological aspect of ancestor with PANTHER:PTN000080571 cytoplasmic translation ; GO:0002181 | traceable author statement maturation of SSU-rRNA ; GO:0030490 | inferred from biological aspect of ancestor with PANTHER:PTN000080571 cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022627 wing disc development ; GO:0035220 | inferred from mutant phenotype cytosolic small ribosomal subunit ; GO:0022627 | inferred from sequence or structural similarity with SGD:S000005693 cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement "CG15527, RpS28a" "IPR000289:Ribosomal protein S28e, IPR012340:Nucleic acid-binding, OB-fold, IPR028626:Ribosomal protein S28e conserved site" CG15527 27-Aug-18 DroID_v2018_08 Drer\rps28 "Scer\RPS28A, Scer\RPS28B" Cele\rps-28 Xtro\rps28p9 Mmus\Rps28 Hsap\RPS28 viable "wing,macrochaeta,ectopic" FBgn0085461 CG34432 - http://flybase.org/reports/FBgn0085461 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG34432, CG15541" - CG34432 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065598 l(2)SH0880 lethal (2) SH0880 http://flybase.org/reports/FBgn0065598 gene - - - "l(2)SH0880, l(2)SH2 0880" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0260099 2L3443 - http://flybase.org/reports/FBgn0260099 gene - "terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - 2L3443 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" "terminal tracheal cell,somatic clone,embryonic/larval tracheal system" FBgn0010425 epsilonTry epsilonTrypsin http://flybase.org/reports/FBgn0010425 FBgn0040762 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "SP88, Try, DmEpsilonTry, epsilon, epsilonTry, CG18681" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG18681 27-Aug-18 DroID_v2018_08 "Drer\prss60.3, Drer\LOC562139, Drer\si:dkeyp-93a5.2, Drer\zgc:112160, Drer\prss60.2, Drer\zgc:163079, Drer\prss60.1, Drer\zgc:112038, Drer\tmprss4b, Drer\zgc:55888, Drer\zgc:92590, Drer\zgc:153968, Drer\ctrl, Drer\try, Drer\zgc:123295" - "Cele\svh-1, Cele\try-1" - "Mmus\2210010C04Rik, Mmus\Try4, Mmus\Prss53, Mmus\Try10, Mmus\Prss55, Mmus\Gm5771, Mmus\Prss36, Mmus\Elane, Mmus\Prss3, Mmus\Prss34, Mmus\Prss1, Mmus\Gm10334, Mmus\Prss2" "Hsap\PRSS36, Hsap\PRSS53, Hsap\ELANE, Hsap\PRSS1, Hsap\PRSS3" viable FBgn0036892 Lon Lon protease http://flybase.org/reports/FBgn0036892 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959, InterPro:IPR004815, InterPro:IPR027065 mitochondrial light strand promoter anti-sense binding ; GO:0070361 | inferred from biological aspect of ancestor with PANTHER:PTN000005479 ATP-dependent peptidase activity ; GO:0004176 | inferred from biological aspect of ancestor with PANTHER:PTN002464028 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence or structural similarity with UniProtKB:P36776" mitochondrion organization ; GO:0007005 | inferred from mutant phenotype positive regulation of protein catabolic process ; GO:0045732 | inferred from mutant phenotype misfolded or incompletely synthesized protein catabolic process ; GO:0006515 | inferred from biological aspect of ancestor with PANTHER:PTN002464028 mitochondrial matrix ; GO:0005759 | inferred from biological aspect of ancestor with PANTHER:PTN000005479 mitochondrion ; GO:0005739 | inferred from direct assay peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:20598 mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:P36776 "anon-WO0118547.350, CG8798, Lon" "IPR003111:Lon, substrate-binding domain, IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR004815:Lon protease, bacterial/eukaryotic-type, IPR008268:Peptidase S16, active site, IPR027503:Lon protease homolog, chloroplastic/mitochondrial, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR027065:Lon protease, IPR014721:Ribosomal protein S5 domain 2-type fold, subgroup, IPR020568:Ribosomal protein S5 domain 2-type fold, IPR008269:Peptidase S16, Lon proteolytic domain, IPR015947:PUA-like domain" CG8798 27-Aug-18 DroID_v2018_08 "Drer\lonp1, Drer\lonp2" Scer\PIM1 "Cele\lonp-1, Cele\lonp-2, Cele\T23G4.2" "Xtro\lonp2, Xtro\lonp1" "Mmus\Lonp1, Mmus\Lonp2" "Hsap\LONP2, Hsap\LONP1" "developmental rate defective,RU486 conditional,short lived,male,female,viable,visible" trichogen cell DRSC11049 I -2.01838158 -0.017784196 0.305652778 -0.284613394 0.451557122 -0.237235623 FBgn0002928 Ne Nelson's mutant http://flybase.org/reports/FBgn0002928 - gene - - - Ne - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,female,maternal effect,recessive,some die during embryonic stage" FBgn0003879 tu(2)W tumor(2)W http://flybase.org/reports/FBgn0003879 - gene - - - "tu-W, tu(2)W" - - 27-Aug-18 DroID_v2018_08 - - - - - - melanotic mass phenotype FBgn0002152 l(2)KX152 lethal (2) KX152 http://flybase.org/reports/FBgn0002152 - gene - - - l(2)KX152 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0265339 asRNA:CR44293 - http://flybase.org/reports/FBgn0265339 non_protein_coding_gene - - - CR44293 - CR44293 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267080 lncRNA:CR45524 - http://flybase.org/reports/FBgn0267080 non_protein_coding_gene - - - CR45524 - CR45524 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0023158 Su(mg)2-1 Suppressor of modifier of gypsy 2-1 http://flybase.org/reports/FBgn0023158 - gene - - - Su(mg)2-1 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035248 CG13919 - http://flybase.org/reports/FBgn0035248 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13919 IPR019396:Transmembrane Fragile-X-F-associated protein CG13919 27-Aug-18 DroID_v2018_08 "Drer\tmem60, Drer\tmem185" - - "Xtro\tmem60, Xtro\tmem185a" "Mmus\Tmem60, Mmus\Tmem185a" "Hsap\TMEM185A, Hsap\TMEM185B, Hsap\TMEM60" viable FBgn0030573 nmdyn-D6 nmdyn-D6 http://flybase.org/reports/FBgn0030573 protein_coding_gene nucleoside diphosphate kinase activity ; GO:0004550 | inferred from sequence or structural similarity with SGD:S000001550 CTP biosynthetic process ; GO:0006241 | inferred from electronic annotation with InterPro:IPR001564 UTP biosynthetic process ; GO:0006228 | inferred from electronic annotation with InterPro:IPR001564 GTP biosynthetic process ; GO:0006183 | inferred from electronic annotation with InterPro:IPR001564 nucleoside diphosphate phosphorylation ; GO:0006165 | inferred from sequence or structural similarity with SGD:S000001550 nucleoside triphosphate biosynthetic process ; GO:0009142 | inferred from sequence or structural similarity with SGD:S000001550 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with SGD:S000001550 "CG5310, nmdyn-D6" "IPR001564:Nucleoside diphosphate kinase, IPR023005:Nucleoside diphosphate kinase, active site" CG5310 27-Aug-18 DroID_v2018_08 "Drer\nme4, Drer\nme2b.1, Drer\nme6, Drer\nme7, Drer\nme5" Scer\YNK1 Cele\Y48G8AL.15 "Xtro\nme3, Xtro\nme5, Xtro\nme6, Xtro\nme7, Xtro\nme9, Xtro\nme4, Xtro\nme2" "Mmus\Nme7, Mmus\Nme5, Mmus\Nme4, Mmus\Nme8, Mmus\Nme3, Mmus\Nme1, Mmus\Nme2, Mmus\Nme6" "Hsap\NME5, Hsap\NME4, Hsap\NME7, Hsap\NME8, Hsap\NME3, Hsap\NME1, Hsap\NME2, Hsap\NME6" viable FBgn0259342 C170 - http://flybase.org/reports/FBgn0259342 gene - - - C170 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing,wing vein" FBgn0260641 Hsf::nkd - http://flybase.org/reports/FBgn0260641 engineered_fusion_gene - - - Hsf::nkd - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005372 x1 x1 http://flybase.org/reports/FBgn0005372 - gene - - - x1 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267513 28SrRNA-Psi:CR45853 28S ribosomal RNA pseudogene:CR45853 http://flybase.org/reports/FBgn0267513 pseudogene_attribute - - - "28SrRNA-Psi:CR45853, CR45853" - CR45853 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037654 CG11983 - http://flybase.org/reports/FBgn0037654 protein_coding_gene - - - CG11983 - CG11983 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible" trichogen cell DRSC14458 K 0.637871752 -0.263519958 -0.06034821 0.005325517 -1.525328795 0.521638063 FBgn0032913 CG9259 - http://flybase.org/reports/FBgn0032913 protein_coding_gene - - - CG9259 "IPR015897:CHK kinase-like, IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain" CG9259 27-Aug-18 DroID_v2018_08 - - "Cele\dhs-27, Cele\F56A4.5, Cele\F59B1.10, Cele\E02C12.8, Cele\T16G1.3, Cele\E02C12.6, Cele\C04F6.7, Cele\Y11D7A.8, Cele\nhr-246, Cele\H37A05.2, Cele\C29F7.2, Cele\F58B4.5, Cele\T16G1.6, Cele\H06H21.8, Cele\Y45G12C.4, Cele\F49C12.7, Cele\E02C12.9, Cele\C29F7.1, Cele\E02C12.10, Cele\F59B1.8, Cele\C18B10.6, Cele\F20D6.5" - - - viable FBgn0065218 l(2)SH2238 lethal (2) SH2238 http://flybase.org/reports/FBgn0065218 gene - - - "l(2)SH2238, l(2)SH2 2238" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0052033 CG32033 - http://flybase.org/reports/FBgn0052033 protein_coding_gene - - - CG32033 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060528 l(3)S101710 lethal (3) S101710 http://flybase.org/reports/FBgn0060528 gene - - - "1017/10, l(3)S101710" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0085808 CR41591 - http://flybase.org/reports/FBgn0085808 rRNA_gene - - - CR41591 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0014050 Su(tor)2-28 Su(tor)2-28 http://flybase.org/reports/FBgn0014050 - gene - - - Su(tor)2-28 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,maternal effect,recessive" FBgn0032464 Vha68-3 Vacuolar H[+] ATPase 68kD subunit 3 http://flybase.org/reports/FBgn0032464 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000194, InterPro:IPR020003 proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from biological aspect of ancestor with PANTHER:PTN000389800 proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | contributes_to inferred by curator from GO:0033176" "ATP metabolic process ; GO:0046034 | inferred from electronic annotation with InterPro:IPR004100, InterPro:IPR022878 ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from electronic annotation with InterPro:IPR000793, InterPro:IPR005725 ATP hydrolysis coupled proton transport ; GO:0015991 | inferred by curator from GO:0033176" "proton-transporting V-type ATPase, V1 domain ; GO:0033180 | inferred from electronic annotation with InterPro:IPR005725 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000389800 lysosomal membrane ; GO:0005765 | inferred from biological aspect of ancestor with PANTHER:PTN001032512 proton-transporting V-type ATPase complex ; GO:0033176 | inferred from sequence or structural similarity with Vha68-2" "vha68-3, CG5075, Vha68-3, Vha68, vha67-3" "IPR000194:ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain, IPR004100:ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain, IPR005725:ATPase, V1 complex, subunit A, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR024034:ATPase, F1/V1 complex, beta/alpha subunit, C-terminal, IPR020003:ATPase, alpha/beta subunit, nucleotide-binding domain, active site, IPR022878:V-type ATP synthase catalytic alpha chain, IPR031686:ATPsynthase alpha/beta subunit, N-terminal extension" CG5075 27-Aug-18 DroID_v2018_08 "Drer\atp6v1ab, Drer\atp6v1aa" Scer\VMA1 Cele\vha-13 Xtro\atp6v1a Mmus\Atp6v1a Hsap\ATP6V1A viable FBgn0028617 l(2)35Ch lethal (2) 35Ch http://flybase.org/reports/FBgn0028617 gene - - - l(2)35Ch - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033018 CG10453 - http://flybase.org/reports/FBgn0033018 protein_coding_gene - - - CG10453 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0069298 amfos amigo de fos http://flybase.org/reports/FBgn0069298 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available amfos - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0020356 anon-2Da anon-2Da http://flybase.org/reports/FBgn0020356 - gene - - - "2D3, anon-2Da" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0053284 CG33284 - http://flybase.org/reports/FBgn0053284 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs10b10, CG33284" - CG33284 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033484 CG2269 - http://flybase.org/reports/FBgn0033484 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon-WO0118547.141, CG2269" - CG2269 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264633 bulgy bulgy http://flybase.org/reports/FBgn0264633 gene - "trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - bulgy - - 27-Aug-18 DroID_v2018_08 - - - - - - "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0040782 CG12827 - http://flybase.org/reports/FBgn0040782 protein_coding_gene - - - CG12827 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039597 CG9997 - http://flybase.org/reports/FBgn0039597 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern protein localization ; GO:0008104 | inferred from mutant phenotype regulation of female receptivity, post-mating ; GO:0046008 | inferred from mutant phenotype sperm competition ; GO:0046692 | inferred from direct assay" extracellular space ; GO:0005615 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence model CG9997 "IPR009003:Peptidase S1, PA clan, IPR001254:Serine proteases, trypsin domain" CG9997 27-Aug-18 DroID_v2018_08 - - - - - Hsap\TMPRSS11B "mating rhythm defective,viable" FBgn0265166 asRNA:CR44235 - http://flybase.org/reports/FBgn0265166 non_protein_coding_gene - - - CR44235 - CR44235 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0013316 Pcp15 Pupal-cuticle-protein-15kD http://flybase.org/reports/FBgn0013316 - gene - - - Pcp15 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034940 CG16787 - http://flybase.org/reports/FBgn0034940 protein_coding_gene - - - CG16787 IPR018790:Protein of unknown function DUF2358 CG16787 27-Aug-18 DroID_v2018_08 Drer\si:ch211-215a10.4 - "Cele\Y48E1C.4, Cele\C27B7.2" Xtro\c6orf136 Mmus\2310061I04Rik Hsap\C6orf136 "lethal - all die before end of pupal stage,some die during pupal stage,lethal,body color defective" mesothoracic tergum FBgn0060394 l(3)S132802b lethal (3) S132802b http://flybase.org/reports/FBgn0060394 gene - - - "1328/02, l(3)S132802b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0067745 l(1)G0265 lethal (1) G0265 http://flybase.org/reports/FBgn0067745 gene - - - l(1)G0265 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0017628 Eig44C Eig44C http://flybase.org/reports/FBgn0017628 - gene - - - "Eig44, Eig44C" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0003302 rux roughex http://flybase.org/reports/FBgn0003302 - protein_coding_gene - regulation of meiotic nuclear division ; GO:0040020 | traceable author statement eye-antennal disc morphogenesis ; GO:0007455 | non-traceable author statement mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype regulation of exit from mitosis ; GO:0007096 | traceable author statement regulation of cell cycle ; GO:0051726 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "rux, Rux, CG4336" IPR009259:Drosophila roughex CG4336 27-Aug-18 DroID_v2018_08 - - - - - - " embryonic stage , larval stage , adult stage , larval stage && adult stage " imaginal disc

"viable,locomotor behavior defective,fertile,visible,recessive,male sterile,cytokinesis defective,wild-type,mitotic cell cycle defective" "eye,cyst cell,Nebenkern,onion stage spermatid,mitotic cell cycle,photoreceptor cell,S phase | ectopic,eye disc,photoreceptor cell R8" FBgn0267902 CR46190 - http://flybase.org/reports/FBgn0267902 pseudogene_attribute - - - "CR46190, CG12717-related" - CR46190 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259311 EP-M32 - http://flybase.org/reports/FBgn0259311 gene - - - EP-M32 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible wing vein FBgn0259591 B0771 - http://flybase.org/reports/FBgn0259591 gene - - - B0771 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "macrochaeta,supernumerary" FBgn0065380 l(2)SH1667 lethal (2) SH1667 http://flybase.org/reports/FBgn0065380 gene - - - "l(2)SH1667, l(2)SH2 1667" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0031728 Hsp60C Heat shock protein 60C http://flybase.org/reports/FBgn0031728 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002423, InterPro:IPR018370 unfolded protein binding ; GO:0051082 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 protein binding involved in protein folding ; GO:0044183 | inferred from biological aspect of ancestor with PANTHER:PTN000143677" protein refolding ; GO:0042026 | inferred from electronic annotation with InterPro:IPR001844 protein import into mitochondrial intermembrane space ; GO:0045041 | inferred from biological aspect of ancestor with PANTHER:PTN000143508 oogenesis ; GO:0048477 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype protein targeting to mitochondrion ; GO:0006626 | inferred from sequence or structural similarity with UniProtKB:P10809 chaperone-mediated protein folding ; GO:0061077 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 open tracheal system development ; GO:0007424 | inferred from mutant phenotype 'de novo' protein folding ; GO:0006458 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 'de novo' protein folding ; GO:0006458 | inferred from sequence or structural similarity with UniProtKB:P10809 female germline ring canal formation ; GO:0007301 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype apoptotic mitochondrial changes ; GO:0008637 | inferred from biological aspect of ancestor with PANTHER:PTN000143510 mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:P10809 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000888029 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000143507 "CG7235, bs36d10.y1, Hsp60C, A4V087_DROME, Hsp64, Dm25E, HSP60C" "IPR018370:Chaperonin Cpn60, conserved site, IPR001844:Chaperonin Cpn60, IPR002423:Chaperonin Cpn60/TCP-1 family, IPR027409:GroEL-like apical domain, IPR027413:GroEL-like equatorial domain" CG7235 27-Aug-18 DroID_v2018_08 Drer\hspd1 "Scer\TCM62, Scer\HSP60" Cele\hsp-60 Xtro\hspd1 Mmus\Hspd1 Hsap\HSPD1 "sterile,flight defective,partially lethal - majority die,some die during first instar larval stage,viable" "embryonic/larval trachea,eye,antenna,macrochaeta,testis,seminal vesicle" DRSC29438 K 0.475078311 -0.175850628 -0.115676115 -0.299778593 0.635373882 -1.624587631 FBgn0259662 B0572 - http://flybase.org/reports/FBgn0259662 gene - - - B0572 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing,wing vein" FBgn0001362 l(1)1Fa lethal (1) 1Fa http://flybase.org/reports/FBgn0001362 - gene - - - l(1)1Fa - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0051718 Ir31a Ionotropic receptor 31a http://flybase.org/reports/FBgn0051718 protein_coding_gene ionotropic glutamate receptor activity ; GO:0004970 | inferred from electronic annotation with InterPro:IPR001320 ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus involved in sensory perception ; GO:0050907 | inferred from expression pattern membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001320 integral component of membrane ; GO:0016021 | inferred from sequence model "Ir31a, IR31a, CG31718, DmelIR31a" IPR001320:Ionotropic glutamate receptor CG31718 27-Aug-18 DroID_v2018_08 "Drer\grid1a, Drer\LOC100537813, Drer\grid1b" - Cele\glr-8 - "Mmus\Grik4, Mmus\Grik5, Mmus\Grid1" "Hsap\GRID1, Hsap\GRIK4" "viable,fertile" FBgn0262842 CG43206 - http://flybase.org/reports/FBgn0262842 protein_coding_gene electron carrier activity ; GO:0009055 | inferred from electronic annotation with InterPro:IPR015089 ubiquinol-cytochrome-c reductase activity ; GO:0008121 | inferred from biological aspect of ancestor with PANTHER:PTN001035181 - mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN001035181 "CG43206, chr3L_16559870_16560394.0" IPR015089:Cytochrome b-c1 complex subunit 10 CG43206 27-Aug-18 DroID_v2018_08 - - Cele\ucr-11 - Mmus\Uqcr11 Hsap\UQCR11 FBgn0026575 hang hangover http://flybase.org/reports/FBgn0026575 "FBgn0030750, FBgn0030751, FBgn0052575, FBgn0062484" protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR003604 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | non-traceable author statement behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype response to heat ; GO:0009408 | inferred from mutant phenotype response to ethanol ; GO:0045471 | inferred from mutant phenotype response to oxidative stress ; GO:0006979 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "BcDNA:LD22118, CG4416, CG4411, LD22118, BcDNA:GM07804, CG32575, hang, HANG" "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type, IPR003604:Matrin/U1-C-like, C2H2-type zinc finger" CG32575 27-Aug-18 DroID_v2018_08 "Drer\gtf3aa, Drer\LOC568955" Scer\PZF1 "Cele\pqm-1, Cele\F21A9.2, Cele\F19C6.3, Cele\F10B5.3" - "Mmus\Gtf3a, Mmus\Thbs3" "Hsap\THBS3, Hsap\GTF3A" "viable,chemical sensitive,short lived,partially lethal - majority die,visible,lethal,female sterile,female semi-sterile" "wing,trichogen cell" FBgn0037022 CG11396 - http://flybase.org/reports/FBgn0037022 protein_coding_gene endopeptidase activity ; GO:0004175 | inferred from biological aspect of ancestor with PANTHER:PTN000491515 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG11396 "IPR011990:Tetratricopeptide-like helical domain, IPR013026:Tetratricopeptide repeat-containing domain, IPR019734:Tetratricopeptide repeat, IPR001440:Tetratricopeptide repeat 1" CG11396 27-Aug-18 DroID_v2018_08 Drer\trappc12 Scer\TMN3 Cele\trpp-12 Xtro\trappc12 Mmus\Trappc12 Hsap\TRAPPC12 "viable,fertile,visible" trichogen cell FBgn0069143 mcl(3)Z4617 mcl(3)Z4617 http://flybase.org/reports/FBgn0069143 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z4617 - - 27-Aug-18 DroID_v2018_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0065289 l(2)SH2016 lethal (2) SH2016 http://flybase.org/reports/FBgn0065289 gene - - - "l(2)SH2016, l(2)SH2 2016" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0011595 FTasealpha Farnesyltransferase alpha subunit http://flybase.org/reports/FBgn0011595 - gene - - - FTasealpha - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036415 CG7768 - http://flybase.org/reports/FBgn0036415 protein_coding_gene "peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from electronic annotation with InterPro:IPR002130, InterPro:IPR020892, InterPro:IPR024936" "protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR002130, InterPro:IPR020892, InterPro:IPR024936 protein peptidyl-prolyl isomerization ; GO:0000413 | inferred from electronic annotation with InterPro:IPR002130" - CG7768 "IPR002130:Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain, IPR024936:Cyclophilin-type peptidyl-prolyl cis-trans isomerase, IPR029000:Cyclophilin-like domain, IPR020892:Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site" CG7768 27-Aug-18 DroID_v2018_08 "Drer\ppil6, Drer\ppig, Drer\LOC103911964, Drer\ppiab, Drer\si:ch1073-55a19.2, Drer\ppie, Drer\ppib, Drer\ppifb, Drer\ppih, Drer\ppiaa, Drer\ppifa, Drer\LOC100333141, Drer\ppid, Drer\nktr" "Scer\CPR3, Scer\CPR6, Scer\CPR1, Scer\CPR4" "Cele\cyn-6, Cele\cyn-5, Cele\cyn-1, Cele\cyn-2, Cele\cyn-7, Cele\T22F3.12, Cele\cyn-9, Cele\Y17G9B.4, Cele\cyn-8, Cele\cyn-3, Cele\cyn-11" "Xtro\nktr, Xtro\ranbp2, Xtro\ppia, Xtro\ppib, Xtro\ppil6, Xtro\ppic, Xtro\ppif, Xtro\ppih, Xtro\ppie, Xtro\ppid" "Mmus\Ppig, Mmus\Ppib, Mmus\Ppil6, Mmus\Ppia, Mmus\Nktr, Mmus\Ppic, Mmus\Ppie, Mmus\Ppif, Mmus\Ppid, Mmus\Ranbp2, Mmus\Ppih" "Hsap\RANBP2, Hsap\RGPD1, Hsap\PPIF, Hsap\PPIE, Hsap\NKTR, Hsap\RGPD8, Hsap\RGPD2, Hsap\PPIAL4E, Hsap\PPIAL4G, Hsap\PPIA, Hsap\PPIAL4D, Hsap\PPIL6, Hsap\RGPD5, Hsap\LOC105371242, Hsap\PPIG, Hsap\PPIAL4A, Hsap\RGPD6, Hsap\PPIH, Hsap\RGPD3, Hsap\RGPD4, Hsap\PPIC, Hsap\PPIAL4C, Hsap\PPID, Hsap\PPIB" viable FBgn0002838 ms(3)K81 male sterile (3) K81 http://flybase.org/reports/FBgn0002838 FBgn0039460 protein_coding_gene - telomere capping ; GO:0016233 | inferred from mutant phenotype "nucleus ; GO:0005634 | inferred from direct assay chromosome, telomeric region ; GO:0000781 | inferred from direct assay condensed nuclear chromosome ; GO:0000794 | inferred from direct assay" "K81, ph, ms(3)k81, ms(3)97Dg, CG14251, ms(3)K81, k81, ms(3)[K81]" - CG14251 27-Aug-18 DroID_v2018_08 - - - - - - "mitotic cell cycle defective,paternal effect,lethal,viable,male sterile" chromosome | paternal effect FBgn0039511 CG3330 - http://flybase.org/reports/FBgn0039511 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - "anon-WO0140519.147, CG3330" - CG3330 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0033454 CG1671 - http://flybase.org/reports/FBgn0033454 protein_coding_gene snoRNA binding ; GO:0030515 | inferred from biological aspect of ancestor with PANTHER:PTN000457905 "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000462 | inferred from biological aspect of ancestor with PANTHER:PTN000457905 neurogenesis ; GO:0022008 | inferred from mutant phenotype cellular response to starvation ; GO:0009267 | inferred from expression pattern" small-subunit processome ; GO:0032040 | inferred from biological aspect of ancestor with PANTHER:PTN000457905 Pwp2p-containing subcomplex of 90S preribosome ; GO:0034388 | inferred from biological aspect of ancestor with PANTHER:PTN000457905 CG1671 "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR013934:Small-subunit processome, Utp13, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat" CG1671 27-Aug-18 DroID_v2018_08 "Drer\wdr5, Drer\tbl3" "Scer\UTP13, Scer\SWD3" "Cele\wdr-5.1, Cele\Y53C12B.1" "Xtro\wdr5, Xtro\tbl3" "Mmus\Tbl3, Mmus\Wdr5b, Mmus\Wdr5" "Hsap\TBL3, Hsap\WDR5B, Hsap\WDR5" "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" FBgn0003703 thv thick vein http://flybase.org/reports/FBgn0003703 - gene - - - thv - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,male fertile,female fertile,reduced,visible,recessive,eye color defective,poor,male,body color defective" "wing,wing vein,wing vein L1,wing vein L2,eye,wing hair" FBgn0060776 l(3)S060903 lethal (3) S060903 http://flybase.org/reports/FBgn0060776 gene - - - "0609/03, l(3)S060903" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0259795 loopin-1 loopin-1 http://flybase.org/reports/FBgn0259795 protein_coding_gene "aminopeptidase activity ; GO:0004177 | inferred from electronic annotation with InterPro:IPR000819, InterPro:IPR008283, InterPro:IPR011356 metalloexopeptidase activity ; GO:0008235 | inferred from electronic annotation with InterPro:IPR011356 manganese ion binding ; GO:0030145 | inferred from electronic annotation with InterPro:IPR011356" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000819, InterPro:IPR008283" cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR011356 "loopin-1, CG4750, anon-WO0140519.81, kl3 lp-1, kl3lp1, loopin, S-LAP 6" "IPR000819:Peptidase M17, leucyl aminopeptidase, C-terminal, IPR008283:Peptidase M17, leucyl aminopeptidase, N-terminal, IPR011356:Peptidase M17, leucine aminopeptidase/peptidase B" CG4750 27-Aug-18 DroID_v2018_08 "Drer\rfwd2, Drer\zgc:152830, Drer\npepl1, Drer\lap3" - "Cele\lap-2, Cele\lap-1" "Xtro\lap3, Xtro\rfwd2" "Mmus\Npepl1, Mmus\Rfwd2, Mmus\Lap3" "Hsap\LAP3, Hsap\NPEPL1" FBgn0013396 anon-94DEa anon-94DEa http://flybase.org/reports/FBgn0013396 - gene - - - "anon-94DE, anon-94DEa" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037007 CG5059 - http://flybase.org/reports/FBgn0037007 protein_coding_gene - positive regulation of apoptotic process ; GO:0043065 | inferred from electronic annotation with InterPro:IPR010548 regulation of programmed cell death ; GO:0043067 | inferred from biological aspect of ancestor with PANTHER:PTN001032684 mitochondrial outer membrane permeabilization ; GO:0097345 | inferred from biological aspect of ancestor with PANTHER:PTN001032684 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR010548 nucleus ; GO:0005634 | inferred from direct assay mitochondrial outer membrane ; GO:0005741 | inferred from biological aspect of ancestor with PANTHER:PTN001032684 "CG5059, BNIP3" IPR010548:BNIP3 CG5059 27-Aug-18 DroID_v2018_08 "Drer\bnip3, Drer\bnip3la, Drer\zgc:73226, Drer\bnip4, Drer\bnip3lb" - Cele\dct-1 Xtro\bnip3 "Mmus\Bnip3, Mmus\Bnip3l" "Hsap\BNIP3L, Hsap\BNIP3" viable FBgn0036786 skl sickle http://flybase.org/reports/FBgn0036786 protein_coding_gene - cell death ; GO:0008219 | inferred from mutant phenotype inferred from genetic interaction with rpr cell death ; GO:0008219 | inferred from mutant phenotype inferred from genetic interaction with grim apoptotic process ; GO:0006915 | inferred from direct assay cellular response to ionizing radiation ; GO:0071479 | inferred from direct assay apoptotic process ; GO:0006915 | inferred from genetic interaction with nos apoptotic process ; GO:0006915 | non-traceable author statement programmed cell death involved in cell development ; GO:0010623 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "veto, CG13701, Skl, meph, BcDNA:RE14076, skl" - CG13701 27-Aug-18 DroID_v2018_08 - - - - - - "cell death defective,viable,fertile,increased cell death" "EW3 neuron | prepupal stage,EW3 neuron,eye" FBgn0035770 pst pastrel http://flybase.org/reports/FBgn0035770 protein_coding_gene molecular_function ; GO:0003674 | no biological data available long-term memory ; GO:0007616 | inferred from mutant phenotype protein secretion ; GO:0009306 | inferred from mutant phenotype learning or memory ; GO:0007611 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype lipid particle ; GO:0005811 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "pastrel, CG8588, Dm-65, pst" IPR031962:Domain of unknown function DUF4781 CG8588 27-Aug-18 DroID_v2018_08 - - Cele\F02C12.1 - - - "memory defective,stress response defective" FBgn0004961 l(1)17Ae lethal (1) 17Ae http://flybase.org/reports/FBgn0004961 - gene - - - l(1)17Ae - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0050231 tRNA:Phe-GAA-1-5 transfer RNA:Phenylalanine-GAA 1-5 http://flybase.org/reports/FBgn0050231 tRNA_gene UUC codon-amino acid adaptor activity ; GO:0033402 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033402 cytosol ; GO:0005829 | inferred by curator from GO:0033402 "AE002787.trna47-PheGAA, tRNA:F:GAA:AE002787-b, CR30107, CR30231, chr2R.trna30-PheGAA, tRNA-Phe-GAA-1-5, tRNA:Phe-GAA-1-5, tRNA:CR30231, UUC" - CR30231 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0261605 M(2)34BC Minute (2) 34BC http://flybase.org/reports/FBgn0261605 gene - - - M(2)34BC - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0013507 l(1)U10 lethal (1) U10 http://flybase.org/reports/FBgn0013507 - gene - - - "U-10, l(1)U10" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0011890 tRNA:Lys-CTT-1-5 transfer RNA:Lysine-CTT 1-5 http://flybase.org/reports/FBgn0011890 "FBgn0003795, FBgn0011886, FBgn0050315, FBgn0050515, FBgn0060188" tRNA_gene AAG codon-amino acid adaptor activity ; GO:0033444 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033444 cytosol ; GO:0005829 | inferred by curator from GO:0033444 "35SLys, tRNA[Lys][[2]], AE002769.trna3-LysCTT, tRNA:K2, tRNA:K:CTT:AE002769-a, tRNA:lys2:42Ad, CR30315, CR30515, tRNAlys, chr2R.trna94-LysCTT, tRNA-Lys-CTT-1-5, tRNA:Lys-CTT-1-5, tRNA:K2:42Ad, AAG" - CR30515 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0014850 Eig71Ej Eig71Ej http://flybase.org/reports/FBgn0014850 - protein_coding_gene - salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern autophagic cell death ; GO:0048102 | inferred from expression pattern metamorphosis ; GO:0007552 | inferred from expression pattern defense response to bacterium ; GO:0042742 | inferred from sequence or structural similarity with MGI:MGI:94880 extracellular region ; GO:0005576 | inferred from sequence model "L71, L71-10, CG7588, Eig71Ej" IPR003475:Insect protein of unknown function CG7588 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0267196 lncRNA:CR45636 - http://flybase.org/reports/FBgn0267196 non_protein_coding_gene - - - "CR45636, lincRNA.790" - CR45636 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0014146 dfk distal of forkhead http://flybase.org/reports/FBgn0014146 - gene - - - "dfh, dfk" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0013379 aagp armadillo-associated glycoprotein http://flybase.org/reports/FBgn0013379 - gene - - - aagp - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034443 cer crammer http://flybase.org/reports/FBgn0034443 protein_coding_gene cysteine-type peptidase activity ; GO:0008234 | inferred from electronic annotation with InterPro:IPR013128 cysteine-type endopeptidase inhibitor activity ; GO:0004869 | inferred from direct assay short-term memory ; GO:0007614 | inferred from direct assay inhibition of cysteine-type endopeptidase activity ; GO:0097340 | inferred from direct assay long-term memory ; GO:0007616 | inferred from mutant phenotype endomembrane system ; GO:0012505 | inferred from direct assay lysosome ; GO:0005764 | inferred from sequence model "CG10460, cer, D/CTLA-2, CER" "IPR013201:Cathepsin propeptide inhibitor domain (I29), IPR013128:Peptidase C1A" CG10460 27-Aug-18 DroID_v2018_08 "Drer\ctsc, Drer\ctss1, Drer\si:dkey-239j18.3, Drer\si:dkey-239j18.2, Drer\LOC100536033, Drer\ctsll, Drer\si:dkey-269i1.3, Drer\ctsbb, Drer\ctsba, Drer\ctslb, Drer\wu:fa26c03, Drer\MGC174155, Drer\si:dkey-26g8.4, Drer\LOC100333521, Drer\si:dkey-269i1.4, Drer\cts12, Drer\ctsz, Drer\si:dkey-183k8.2, Drer\ctss2.1, Drer\ctsl.1, Drer\ctsh, Drer\zgc:110239, Drer\zgc:174855, Drer\si:dkey-228a15.1, Drer\si:dkey-267n13.1, Drer\ctss2.2, Drer\zgc:174153, Drer\ctsk, Drer\ctsla, Drer\zgc:103438, Drer\MGC174857" - Cele\cpl-1 "Xtro\ctsc, Xtro\ctsl, Xtro\LOC100498238, Xtro\LOC100490139, Xtro\ctsh, Xtro\ctss, Xtro\ctsz, Xtro\ctsv, Xtro\ctsb" "Mmus\Ctss, Mmus\BC051665, Mmus\Cts6, Mmus\4930486L24Rik, Mmus\Ctsll3, Mmus\Ctsq, Mmus\Cts8, Mmus\Ctsm, Mmus\Ctla2b, Mmus\Ctsh, Mmus\Ctla2a, Mmus\Ctsj, Mmus\Ctsl, Mmus\Ctsz, Mmus\Ctsr, Mmus\Cts7, Mmus\Ctsk, Mmus\Ctsc, Mmus\Cts3, Mmus\Ctsb" "Hsap\CTSH, Hsap\CTSL, Hsap\CTSV, Hsap\CTSS, Hsap\CTSZ, Hsap\CTSC, Hsap\CTSB, Hsap\CTSK" "memory defective,recessive,feeding behavior defective,viable" FBgn0032280 CG17105 - http://flybase.org/reports/FBgn0032280 protein_coding_gene - - - CG17105 - CG17105 27-Aug-18 DroID_v2018_08 - - Cele\nlp-24 - - - viable FBgn0062654 EP3621 EP3621 http://flybase.org/reports/FBgn0062654 gene - - - "EP(3)3621, EP3621" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040674 CG9445 - http://flybase.org/reports/FBgn0040674 protein_coding_gene - mesoderm development ; GO:0007498 | inferred from expression pattern - CG9445 - CG9445 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0065151 l(3)SH066 lethal (3) SH066 http://flybase.org/reports/FBgn0065151 gene - - - "l(3)SH066, l(2)SH3 066" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0263129 Cbl::drk Cbl::drk http://flybase.org/reports/FBgn0263129 engineered_fusion_gene - - - Cbl::drk - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034352 CG17669 - http://flybase.org/reports/FBgn0034352 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG17669 "IPR027974:Domain of unknown function DUF4470, IPR028235:Dynein assembly factor 3, C-terminal domain" CG17669 27-Aug-18 DroID_v2018_08 "Drer\dnaaf3l, Drer\dnaaf3" - - Xtro\dnaaf3 Mmus\Dnaaf3 Hsap\DNAAF3 viable FBgn0085690 CG41559 - http://flybase.org/reports/FBgn0085690 protein_coding_gene - - - CG41559 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0067856 Theseus Theseus http://flybase.org/reports/FBgn0067856 gene G-protein coupled receptor activity ; GO:0004930 | non-traceable author statement G-protein coupled receptor signaling pathway ; GO:0007186 | non-traceable author statement germ cell migration ; GO:0008354 | non-traceable author statement integral component of membrane ; GO:0016021 | inferred by curator from GO:0004930 "theseus, Theseus" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259969 Sfp65A Seminal fluid protein 65A http://flybase.org/reports/FBgn0259969 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "Sfp65A, CG42479" - CG42479 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0086383 BG01533 - http://flybase.org/reports/FBgn0086383 gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - BG01533 - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,smell perception defective" FBgn0053109 CG33109 - http://flybase.org/reports/FBgn0053109 protein_coding_gene - - - "CG9645, CG33109, cg9645" - CG33109 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0022095 l(2)k07219 lethal (2) k07219 http://flybase.org/reports/FBgn0022095 - gene - - - l(2)k07219 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0037330 mRpL44 mitochondrial ribosomal protein L44 http://flybase.org/reports/FBgn0037330 protein_coding_gene ribonuclease III activity ; GO:0004525 | inferred from electronic annotation with InterPro:IPR000999 structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:Q9H9J2 RNA processing ; GO:0006396 | inferred from electronic annotation with InterPro:IPR000999 mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial translation ; GO:0032543 | inferred by curator from GO:0005762 neurogenesis ; GO:0022008 | inferred from mutant phenotype mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with UniProtKB:Q9H9J2 "MRP-L44, CG2109, mRpL44" IPR000999:Ribonuclease III domain CG2109 27-Aug-18 DroID_v2018_08 Drer\mrpl44 Scer\MRPL3 Cele\F02A9.4 Xtro\mrpl44 Mmus\Mrpl44 Hsap\MRPL44 "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0033971 CG10209 - http://flybase.org/reports/FBgn0033971 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR004210 apoptotic process ; GO:0006915 | inferred from electronic annotation with InterPro:IPR026753 nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR026753 CG10209 "IPR004210:BESS motif, IPR026753:Nuclear apoptosis-inducing factor 1, IPR028002:Myb/SANT-like DNA-binding domain" CG10209 27-Aug-18 DroID_v2018_08 "Drer\zgc:153990, Drer\zgc:113149, Drer\si:ch211-261d7.3, Drer\naif1" - - - Mmus\Naif1 Hsap\NAIF1 lethal FBgn0264265 lncRNA:CR43765 - http://flybase.org/reports/FBgn0264265 non_protein_coding_gene - - - "CR43765, lincRNA.231" - CR43765 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035150 Rev1 Rev1 http://flybase.org/reports/FBgn0035150 protein_coding_gene "damaged DNA binding ; GO:0003684 | inferred from electronic annotation with InterPro:IPR012112, InterPro:IPR017961 deoxycytidyl transferase activity ; GO:0017125 | non-traceable author statement deoxycytidyl transferase activity ; GO:0017125 | inferred from sequence or structural similarity with SGD:S000005873" error-prone translesion synthesis ; GO:0042276 | inferred from electronic annotation with InterPro:IPR012112 regulation of double-strand break repair via homologous recombination ; GO:0010569 | inferred from mutant phenotype translesion synthesis ; GO:0019985 | non-traceable author statement translesion synthesis ; GO:0019985 | inferred from sequence or structural similarity with SGD:S000005873 replication fork ; GO:0005657 | inferred from sequence or structural similarity with SGD:S000005873 "Rev1, DmREV1, CG12189, AAF47401, drev1, DmRev1, dREV1, REV1, dRev1, rev1" "IPR017961:DNA polymerase, Y-family, little finger domain, IPR001126:UmuC domain, IPR001357:BRCT domain, IPR012112:DNA repair protein, Rev1, IPR031991:DNA repair protein Rev1, C-terminal" CG12189 27-Aug-18 DroID_v2018_08 Drer\rev1 Scer\REV1 Cele\rev-1 Xtro\rev1 Mmus\Rev1 Hsap\REV1 "radiation sensitive,viable" FBgn0020814 l(3)L3999 lethal (3) L3999 http://flybase.org/reports/FBgn0020814 - gene - - - l(3)L3999 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0027334 l(1)G0004 lethal (1) G0004 http://flybase.org/reports/FBgn0027334 FBgn0031105 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR004088 neurogenesis ; GO:0022008 | inferred from mutant phenotype nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000981817 nucleolus ; GO:0005730 | inferred from sequence or structural similarity with UniProtKB:Q9NRX1 "CG11738, l(1)G0004, l(G0004)" "IPR004088:K Homology domain, type 1, IPR004087:K Homology domain" CG11738 27-Aug-18 DroID_v2018_08 Drer\pno1 Scer\PNO1 Cele\Y53C12B.2 Xtro\pno1 Mmus\Pno1 Hsap\PNO1 "lethal - all die before end of larval stage,some die during larval stage,lethal,recessive,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0024842 per::Dpse\per per::Dpse\per http://flybase.org/reports/FBgn0024842 - engineered_fusion_gene - - - per::Dpse\per - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004019 wobA wobbly A http://flybase.org/reports/FBgn0004019 - gene - - - wobA - - 27-Aug-18 DroID_v2018_08 - - - - - - uncoordinated FBgn0051471 tRNA:Thr-AGT-1-7 transfer RNA:Threonine-AGT 1-7 http://flybase.org/reports/FBgn0051471 tRNA_gene ACU codon-amino acid adaptor activity ; GO:0033437 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033437 cytosol ; GO:0005829 | inferred by curator from GO:0033437 "AE002708.trna22-ThrAGT, tRNA:T:AGT:AE002708-b, CR31471, tRNA[[Thr]], chr3R.trna28-ThrAGT, tRNA-Thr-AGT-1-7, tRNA:Thr-AGT-1-7, tRNA:CR31471, ACU" - CR31471 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035687 Prdm13 - http://flybase.org/reports/FBgn0035687 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - CG13296 "IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG13296 27-Aug-18 DroID_v2018_08 "Drer\zgc:173619, Drer\prdm13, Drer\zbtb12.2" - Cele\fezf-1 - "Mmus\Prdm13, Mmus\Zbtb12" "Hsap\PRDM13, Hsap\ZNF366, Hsap\ZBTB12" "viable,visible" trichogen cell FBgn0265017 lncRNA:CR43751 - http://flybase.org/reports/FBgn0265017 non_protein_coding_gene - - - "CR43751, CG43751, CG15383" - CR43751 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0058209 CG40209 - http://flybase.org/reports/FBgn0058209 protein_coding_gene - - - CG40209 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0011431 l(3)j11B2 lethal (3) j11B2 http://flybase.org/reports/FBgn0011431 FBgn0024524 gene - - - "l(3)j3E5, l(3)j11B2" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0038427 ema endosomal maturation defective http://flybase.org/reports/FBgn0038427 protein_coding_gene Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab39 endosome to lysosome transport ; GO:0008333 | inferred from mutant phenotype endosomal transport ; GO:0016197 | inferred from genetic interaction withFB:FBgn0261241 integral component of membrane ; GO:0016021 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay late endosome ; GO:0005770 | inferred from direct assay late endosome ; GO:0005770 | colocalizes_with inferred from direct assay "ema, CG12753, Ema" IPR019155:Uncharacterised protein family FPL CG12753 27-Aug-18 DroID_v2018_08 Drer\clec16a - Cele\gop-1 Xtro\clec16a Mmus\Clec16a Hsap\CLEC16A "neuroanatomy defective,recessive,lethal - all die before end of P-stage,some die during P-stage,viable" "terminal bouton,endosome,terminal boutonExel7330),neuromuscular junctionExel7330)" FBgn0035336 CG9004 - http://flybase.org/reports/FBgn0035336 protein_coding_gene RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000427685 neurogenesis ; GO:0022008 | inferred from mutant phenotype ribosomal small subunit biogenesis ; GO:0042274 | inferred from biological aspect of ancestor with PANTHER:PTN000427762 nucleolus ; GO:0005730 | inferred from sequence or structural similarity with UniProtKB:Q5C9Z4 nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000427762 CG9004 "IPR003890:MIF4G-like, type 3, IPR003891:Initiation factor eIF-4 gamma, MA3, IPR016024:Armadillo-type fold" CG9004 27-Aug-18 DroID_v2018_08 Drer\nom1 Scer\SGD1 Cele\Y52B11A.10 Xtro\nom1 Mmus\Nom1 Hsap\NOM1 "lethal,neuroanatomy defective,viable,visible" "ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0259960 CG42470 - http://flybase.org/reports/FBgn0259960 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42470 - CG42470 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033918 CG8531 - http://flybase.org/reports/FBgn0033918 protein_coding_gene ATPase activator activity ; GO:0001671 | inferred from sequence or structural similarity with SGD:S000004080 protein import into mitochondrial matrix ; GO:0030150 | inferred from sequence or structural similarity with SGD:S000004080 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with SGD:S000004080 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000004080 CG8531 "IPR001623:DnaJ domain, IPR024586:DnaJ-like protein C11, C-terminal" CG8531 27-Aug-18 DroID_v2018_08 Drer\dnajc11 "Scer\SCJ1, Scer\JJJ1, Scer\APJ1, Scer\ERJ5, Scer\XDJ1" Cele\dnj-9 Xtro\dnajc11 Mmus\Dnajc11 Hsap\DNAJC11 "viable,fertile" "wing,posterior compartment" FBgn0262432 mir-8 mir-8 stem loop http://flybase.org/reports/FBgn0262432 miRNA_gene - positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype gene silencing by miRNA ; GO:0035195 | inferred from direct assay Wnt signaling pathway ; GO:0016055 | inferred from mutant phenotype neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype female pigmentation ; GO:0048095 | inferred from mutant phenotype positive regulation of eclosion ; GO:0045805 | inferred from mutant phenotype negative regulation of neurogenesis ; GO:0050768 | inferred from mutant phenotype glial cell growth ; GO:0042065 | inferred from mutant phenotype glial cell development ; GO:0021782 | inferred from mutant phenotype neuroblast development ; GO:0014019 | inferred from mutant phenotype negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from genetic interaction with spi positive regulation of synaptic growth at neuromuscular junction ; GO:0045887 | inferred from mutant phenotype subsynaptic reticulum organization ; GO:1990255 | inferred from mutant phenotype imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype - "miR-8, dme-mir-8, mir-8, 8, MIR-8, CR42988, CR33018, 8 mir, dme-miR-8, MiR-8, miR8, CR33562, mir-8*, mir-8S, mir8S, dme-miR-8-3p" - CR42988 27-Aug-18 DroID_v2018_08 - - - - - - embryonic stage -- adult stage FBgn0060491 l(3)S110006b lethal (3) S110006b http://flybase.org/reports/FBgn0060491 gene - - - "1100/06, l(3)S110006b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0051102 CG31102 - http://flybase.org/reports/FBgn0051102 protein_coding_gene - - - "CG10634, CG31102" "IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain, IPR015897:CHK kinase-like" CG31102 27-Aug-18 DroID_v2018_08 Drer\LOC100150280 - "Cele\F59B1.8, Cele\C29F7.2, Cele\F59B1.10, Cele\dhs-27, Cele\C29F7.1, Cele\H06H21.8, Cele\nhr-246" - - - viable DRSC14260 I -0.657362049 7.161830223 0.170485258 0.442561105 -0.065256733 0.448166557 FBgn0063415 l(3)3450-H lethal (3) 3450-H http://flybase.org/reports/FBgn0063415 gene - - - l(3)3450-H - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0053437 5SrRNA:CR33437 5SrRNA:CR33437 http://flybase.org/reports/FBgn0053437 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33437, 5SrRNA:CR33437" - CR33437 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264888 CR44079 - http://flybase.org/reports/FBgn0264888 pseudogene_attribute - - - CR44079 - CR44079 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040321 GNBP3 Gram-negative bacteria binding protein 3 http://flybase.org/reports/FBgn0040321 protein_coding_gene signaling pattern recognition receptor activity ; GO:0008329 | inferred from sequence or structural similarity with GNBP1 beta-glucanase activity ; GO:0052736 | NOT inferred from key residues lipopolysaccharide binding ; GO:0001530 | inferred from direct assay (1->3)-beta-D-glucan binding ; GO:0001872 | inferred from direct assay carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR000757 regulation of innate immune response ; GO:0045088 | inferred from sequence or structural similarity with UniProtKB:Q9NHB0 detection of molecule of fungal origin ; GO:0032491 | inferred from direct assay innate immune response-activating signal transduction ; GO:0002758 | inferred from sequence or structural similarity with GNBP1 response to fungus ; GO:0009620 | non-traceable author statement cell surface ; GO:0009986 | inferred from direct assay extracellular region ; GO:0005576 | inferred from sequence or structural similarity with UniProtKB:Q9NHB0 "Hades, GNBP, DGNBP-3, CG5008, GNBP3, gnbp3, GNBP-3, Gnbp3" "IPR000757:Glycoside hydrolase family 16, IPR013320:Concanavalin A-like lectin/glucanase domain, IPR031756:Beta-1,3-glucan-binding protein, N-terminal" CG5008 27-Aug-18 DroID_v2018_08 - "Scer\CRR1, Scer\CRH1, Scer\UTR2" - - - - "immune response defective,viable" FBgn0001340 l(1)1Bh lethal (1) 1Bh http://flybase.org/reports/FBgn0001340 - gene - - - "l(1)PB, l(1)1Bh" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,polyphasic,lethal - all die before end of pupal stage,recessive,some die during pupal stage,partially lethal - majority die,visible" wing FBgn0032057 CG9287 - http://flybase.org/reports/FBgn0032057 protein_coding_gene - - - CG9287 "IPR029058:Alpha/Beta hydrolase fold, IPR002018:Carboxylesterase, type B" CG9287 27-Aug-18 DroID_v2018_08 "Drer\cell, Drer\ces3, Drer\ces2, Drer\nlgn2a, Drer\si:ch211-93f2.1, Drer\cel.1, Drer\nlgn4b, Drer\nlgn3b, Drer\nlgn3a, Drer\nlgn4a, Drer\nlgn1, Drer\nlgn2b" - "Cele\K07C11.4, Cele\ges-1, Cele\glit-1, Cele\Y71H2AM.13, Cele\T28C12.4, Cele\F07C4.12, Cele\R173.3, Cele\K11G9.2, Cele\F56C11.6, Cele\F15A8.6" "Xtro\ces2, Xtro\nlgn2, Xtro\LOC100494782, Xtro\nlgn3, Xtro\cel, Xtro\ces3, Xtro\nlgn4x" "Mmus\Ces2e, Mmus\Ces2h, Mmus\Tg, Mmus\Ces3b, Mmus\Ces2g, Mmus\Nlgn3, Mmus\Nlgn2, Mmus\Ces2f, Mmus\Ces3a, Mmus\Ces1b, Mmus\Cel, Mmus\Ces1h, Mmus\Ces4a, Mmus\Ces2b, Mmus\Ces1c, Mmus\Ces5a, Mmus\Ces2c, Mmus\Ces2a, Mmus\Ces1g, Mmus\Ces1e, Mmus\Nlgn1, Mmus\Ces1f, Mmus\Ces1d" "Hsap\NLGN4X, Hsap\CES4A, Hsap\CES1, Hsap\NLGN2, Hsap\NLGN4Y, Hsap\TG, Hsap\CEL, Hsap\CES2, Hsap\NLGN1, Hsap\CES5A, Hsap\CES3, Hsap\NLGN3" "viable,fertile" DRSC03186 I 1.589024852 0.594379983 0.476441683 0.342074121 0.391241399 0.64305324 FBgn0001486 l(1)10Af lethal (1) 10Af http://flybase.org/reports/FBgn0001486 - gene - - - "l(1)EM16, l(1)G11, l(1)EF444, l(1)10Af" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage,maternal effect" "ovariole,germline clone,maternal effect" FBgn0034276 Sardh Sarcosine dehydrogenase http://flybase.org/reports/FBgn0034276 protein_coding_gene sarcosine dehydrogenase activity ; GO:0008480 | inferred from biological aspect of ancestor with PANTHER:PTN001014783 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006076, InterPro:IPR023753 sarcosine catabolic process ; GO:1901053 | inferred from mutant phenotype S-adenosylmethionine cycle ; GO:0033353 | inferred from mutant phenotype" mitochondrial matrix ; GO:0005759 | inferred from biological aspect of ancestor with PANTHER:PTN002302636 "CG6385, Sardh, sardh" "IPR006076:FAD dependent oxidoreductase, IPR006222:Glycine cleavage T-protein-like, N-terminal, IPR013977:Glycine cleavage T-protein, C-terminal barrel domain, IPR029043:Glycine cleavage T-protein/YgfZ, C-terminal domain, IPR032503:FAD dependent oxidoreductase, central domain, IPR023753:FAD/NAD(P)-binding domain" CG6385 27-Aug-18 DroID_v2018_08 "Drer\dmgdh, Drer\pdpr, Drer\sardh" Scer\GCV1 Cele\Y37E3.17 "Xtro\pdpr, Xtro\sardh, Xtro\dmgdh" "Mmus\Pdpr, Mmus\Dmgdh, Mmus\Sardh" "Hsap\DMGDH, Hsap\PDPR, Hsap\SARDH" viable FBgn0060691 l(3)S073414 lethal (3) S073414 http://flybase.org/reports/FBgn0060691 gene - - - "0734/14, l(3)S073414" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0037939 CG14718 - http://flybase.org/reports/FBgn0037939 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001876 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity - - "cg14718, CG14718" "IPR000504:RNA recognition motif domain, IPR001876:Zinc finger, RanBP2-type" CG14718 27-Aug-18 DroID_v2018_08 "Drer\ewsr1b, Drer\ewsr1a, Drer\fus, Drer\taf15" - "Cele\fust-1, Cele\Y65B4A.1" "Xtro\ewsr1, Xtro\fus, Xtro\taf15" "Mmus\Taf15, Mmus\Fus, Mmus\Ewsr1" "Hsap\TAF15, Hsap\FUS, Hsap\EWSR1" viable FBgn0266988 lncRNA:CR45439 - http://flybase.org/reports/FBgn0266988 non_protein_coding_gene - - - CR45439 - CR45439 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264514 lncRNA:CR43913 - http://flybase.org/reports/FBgn0264514 non_protein_coding_gene - - - "CR43913, lincRNA.537" - CR43913 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034576 ND-B14.7 NADH dehydrogenase (ubiquinone) B14.7 subunit http://flybase.org/reports/FBgn0034576 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with HGNC:20371 mitochondrial respiratory chain complex I ; GO:0005747 | inferred from biological aspect of ancestor with PANTHER:PTN001085916 "BcDNA:RH51452, CG9350, ND-B14.7" - CG9350 27-Aug-18 DroID_v2018_08 Drer\ndufa11 - - Xtro\ndufa11 Mmus\Ndufa11 Hsap\NDUFA11 "viable,visible" "trichogen cell,mesothoracic tergum" DRSC04544 IE -0.396405947 -2.465681724 -2.716906957 0.192276773 1.489031791 0.538901356 FBgn0267884 CR46172 - http://flybase.org/reports/FBgn0267884 pseudogene_attribute - - - "CR46172, CG12717-related" - CR46172 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0082371 EP2522 EP2522 http://flybase.org/reports/FBgn0082371 gene - - - EP2522 - - 27-Aug-18 DroID_v2018_08 - - - - - - "germline cell,male" FBgn0058330 CG40330 - http://flybase.org/reports/FBgn0058330 protein_coding_gene - - - CG40330 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0017577 Mcm5 Minichromosome maintenance 5 http://flybase.org/reports/FBgn0017577 - protein_coding_gene "chromatin binding ; GO:0003682 | inferred from electronic annotation with InterPro:IPR008048 DNA replication origin binding ; GO:0003688 | inferred from electronic annotation with InterPro:IPR008048 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001208, InterPro:IPR008048, InterPro:IPR018525 3'-5' DNA helicase activity ; GO:0043138 | contributes_to inferred from direct assay" DNA replication initiation ; GO:0006270 | inferred from electronic annotation with InterPro:IPR008048 DNA endoreduplication ; GO:0042023 | inferred from mutant phenotype chromosome condensation ; GO:0030261 | inferred from mutant phenotype meiotic nuclear division ; GO:0007126 | inferred from mutant phenotype resolution of meiotic recombination intermediates ; GO:0000712 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR008048 MCM complex ; GO:0042555 | inferred from electronic annotation with InterPro:IPR008048 "MCM5, mcm5, CG4082, DmMcm5, DmMCM5, PCR4, DmCDC465, DmCDC46, Mcm5, McM5, DmeMCM5" "IPR018525:Mini-chromosome maintenance, conserved site, IPR001208:MCM domain, IPR008048:DNA replication licensing factor Mcm, IPR012340:Nucleic acid-binding, OB-fold, IPR033762:MCM OB domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR027925:MCM N-terminal domain, IPR031327:Mini-chromosome maintenance protein" CG4082 27-Aug-18 DroID_v2018_08 Drer\mcm5 Scer\MCM5 Cele\mcm-5 Xtro\mcm5 Mmus\Mcm5 Hsap\MCM5 "viable,meiotic cell cycle defective,fertile,lethal,recessive,visible" "nuclear chromosome,imaginal disc,trichogen cell" FBgn0267694 lncRNA:CR46030 - http://flybase.org/reports/FBgn0267694 non_protein_coding_gene - - - CR46030 - CR46030 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034356 Pepck2 - http://flybase.org/reports/FBgn0034356 protein_coding_gene GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR008209 phosphoenolpyruvate carboxykinase (GTP) activity ; GO:0004613 | inferred from sequence or structural similarity with UniProtKB:Q16822 gluconeogenesis ; GO:0006094 | inferred from sequence or structural similarity with UniProtKB:Q16822 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q16822 "CG10924, PEPCK, pepck2" "IPR008209:Phosphoenolpyruvate carboxykinase, GTP-utilising, IPR018091:Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site, IPR013035:Phosphoenolpyruvate carboxykinase, C-terminal, IPR008210:Phosphoenolpyruvate carboxykinase, N-terminal" CG10924 27-Aug-18 DroID_v2018_08 "Drer\pck2, Drer\pck1" - "Cele\pck-1, Cele\pck-2, Cele\pck-3" "Xtro\pck1, Xtro\pck2" "Mmus\Pck1, Mmus\Pck2" "Hsap\PCK1, Hsap\PCK2" "viable,fertile" FBgn0002176 l(3)7E103 lethal (3) 7E103 http://flybase.org/reports/FBgn0002176 - gene - - - l(3)7E103 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0265401 EP902 - http://flybase.org/reports/FBgn0265401 gene - - - EP902 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0011622 l(2)10610 lethal (2) 10610 http://flybase.org/reports/FBgn0011622 - gene - - - l(2)10610 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0053246 Ste:CG33246 Ste:CG33246 http://flybase.org/reports/FBgn0053246 protein_coding_gene protein kinase regulator activity ; GO:0019887 | inferred from mutant phenotype regulation of protein serine/threonine phosphatase activity ; GO:0080163 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay protein kinase CK2 complex ; GO:0005956 | inferred from direct assay "CG32605, CG33246, Ste:CG33246" "IPR000704:Casein kinase II, regulatory subunit, IPR016149:Casein kinase II, regulatory subunit, alpha-helical" CG33246 27-Aug-18 DroID_v2018_08 Drer\csnk2b "Scer\CKB1, Scer\CKB2" Cele\kin-10 Xtro\csnk2b Mmus\Csnk2b Hsap\CSNK2B FBgn0014877 Roe1 Roe1 http://flybase.org/reports/FBgn0014877 FBgn0064950 protein_coding_gene chaperone binding ; GO:0051087 | inferred from electronic annotation with InterPro:IPR000740 protein homodimerization activity ; GO:0042803 | inferred from electronic annotation with InterPro:IPR000740 adenyl-nucleotide exchange factor activity ; GO:0000774 | inferred from biological aspect of ancestor with PANTHER:PTN000478264 unfolded protein binding ; GO:0051082 | inferred from sequence or structural similarity with UniProtKB:Q8TAA5 unfolded protein binding ; GO:0051082 | inferred from biological aspect of ancestor with PANTHER:PTN000478264 protein import into mitochondrial matrix ; GO:0030150 | inferred from biological aspect of ancestor with PANTHER:PTN000478265 protein folding ; GO:0006457 | inferred from sequence or structural similarity with UniProtKB:Q8TAA5 protein targeting to mitochondrion ; GO:0006626 | inferred from sequence or structural similarity with UniProtKB:Q8TAA5 neurogenesis ; GO:0022008 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:Q8TAA5 presequence translocase-associated import motor ; GO:0001405 | inferred from biological aspect of ancestor with PANTHER:PTN000478265 "DROE1, droe1, BcDNA:GM03203, Droe1, CG6155, Roe1, cg6155" "IPR000740:GrpE nucleotide exchange factor, IPR009012:GrpE nucleotide exchange factor, head, IPR013805:GrpE nucleotide exchange factor, coiled-coil" CG6155 27-Aug-18 DroID_v2018_08 "Drer\grpel1, Drer\grpel2" Scer\MGE1 Cele\C34C12.8 "Xtro\grpel1, Xtro\grpel2" "Mmus\Grpel2, Mmus\Grpel1" "Hsap\GRPEL2, Hsap\GRPEL1" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0061012 l(3)S026111 lethal (3) S026111 http://flybase.org/reports/FBgn0061012 gene - - - "0261/11, l(3)S026111" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0005176 l(2)Stn lethal of Steinmetz http://flybase.org/reports/FBgn0005176 - gene - - - l(2)Stn - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" "eye,cuticle" FBgn0010190 tu-54e tu-54e http://flybase.org/reports/FBgn0010190 - gene - - - tu-54e - - 27-Aug-18 DroID_v2018_08 - - - - - - melanotic mass phenotype FBgn0034654 eIF3k eukaryotic translation initiation factor 3 subunit k http://flybase.org/reports/FBgn0034654 protein_coding_gene ribosome binding ; GO:0043022 | inferred from electronic annotation with InterPro:IPR016020 translation initiation factor activity ; GO:0003743 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000314720 translation initiation factor activity ; GO:0003743 | contributes_to inferred from sequence or structural similarity with HGNC:24656 regulation of translational initiation ; GO:0006446 | inferred from electronic annotation with InterPro:IPR016020 translational initiation ; GO:0006413 | inferred from sequence or structural similarity with HGNC:24656 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:24656 eukaryotic translation initiation factor 3 complex ; GO:0005852 | inferred from biological aspect of ancestor with PANTHER:PTN000314720 eukaryotic translation initiation factor 3 complex ; GO:0005852 | inferred from sequence or structural similarity with HGNC:24656 "CG10306, eIF3k" "IPR009374:Eukaryotic translation initiation factor 3 subunit K, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR016020:Translation initiation factor 3, subunit 12, N-terminal, eukaryotic, IPR016024:Armadillo-type fold, IPR033464:CSN8/PSMD8/EIF3K" CG10306 27-Aug-18 DroID_v2018_08 Drer\eif3k - Cele\eif-3.K Xtro\eif3k Mmus\Eif3k Hsap\EIF3K FBgn0037110 ORMDL ORMDL http://flybase.org/reports/FBgn0037110 protein_coding_gene - negative regulation of ceramide biosynthetic process ; GO:1900060 | inferred from biological aspect of ancestor with PANTHER:PTN000292374 cellular sphingolipid homeostasis ; GO:0090156 | inferred from biological aspect of ancestor with PANTHER:PTN000292374 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR007203 endoplasmic reticulum membrane ; GO:0005789 | inferred from sequence or structural similarity with UniProtKB:Q9P0S3 SPOTS complex ; GO:0035339 | inferred from biological aspect of ancestor with PANTHER:PTN000292374 cytosol ; GO:0005829 | inferred from direct assay "CG14577, ORMDL" IPR007203:ORMDL family CG14577 27-Aug-18 DroID_v2018_08 "Drer\ormdl1, Drer\ormdl2, Drer\ormdl3" "Scer\ORM1, Scer\ORM2" "Cele\T10C6.10, Cele\F29G9.7" "Xtro\ormdl1, Xtro\ormdl2" "Mmus\Ormdl2, Mmus\Ormdl1, Mmus\Ormdl3" "Hsap\ORMDL3, Hsap\ORMDL1, Hsap\ORMDL2" "viable,fertile" FBgn0001646 l(1)dn26 lethal (1) discs normal 26 http://flybase.org/reports/FBgn0001646 - gene - - - "l(1)d.norm.-26, l(1)dn26" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0005299 mei-I3 meiotic I3 http://flybase.org/reports/FBgn0005299 - gene - - - mei-I3 - - 27-Aug-18 DroID_v2018_08 - - - - - - "meiotic cell cycle defective,male,recessive" "meiosis I,meiosis II" FBgn0003902 Two-b Two bristles http://flybase.org/reports/FBgn0003902 FBgn0004615 gene - - - Two-b - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,viable,good" "postvertical bristle,dorsocentral bristle" FBgn0035542 DOR Diabetes and obesity regulated http://flybase.org/reports/FBgn0035542 protein_coding_gene steroid hormone receptor binding ; GO:0035258 | inferred from physical interaction with EcR ligand-dependent nuclear receptor transcription coactivator activity ; GO:0030374 | inferred from direct assay regulation of autophagy ; GO:0010506 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay autophagosome assembly ; GO:0000045 | inferred from biological aspect of ancestor with PANTHER:PTN001270888 ecdysone receptor-mediated signaling pathway ; GO:0035076 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001270888 autophagosome ; GO:0005776 | inferred from biological aspect of ancestor with PANTHER:PTN001270888 nucleus ; GO:0005634 | inferred by curator from GO:0030374 "CG11347, DOR, dDOR" IPR029431:Tumour protein p53-inducible nuclear protein CG11347 27-Aug-18 DroID_v2018_08 "Drer\tp53inp2, Drer\tp53inp1" - - "Xtro\tp53inp1, Xtro\tp53inp2" "Mmus\Trp53inp1, Mmus\Trp53inp2" "Hsap\TP53INP2, Hsap\TP53INP1" "lethal - all die before end of P-stage,some die during P-stage,lethal - all die before end of pupal stage,some die during pupal stage,viable" "anterior pupal spiracle,salivary gland,autophagic vacuole" FBgn0016010 l(3)63Fd lethal (3) 63Fd http://flybase.org/reports/FBgn0016010 - gene - - - "l(3)SH6, l(3)63Fd" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0010121 l(1)8Ab lethal (1) 8Ab http://flybase.org/reports/FBgn0010121 - gene - - - "HF383, l(1)8Ab" - - 27-Aug-18 DroID_v2018_08 - - - - - - "cell lethal,germline clone,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0051162 tRNA:Ser-GCT-2-4 transfer RNA:Serine-GCT 2-4 http://flybase.org/reports/FBgn0051162 tRNA_gene AGC codon-amino acid adaptor activity ; GO:0033446 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033446 cytosol ; GO:0005829 | inferred by curator from GO:0033446 "tRNA[Ser][[2b]], AE002708.trna39-SerGCT, tRNA:S:GCT:AE002708-d, tRNA:ser, tRNA:S, tRNA:ser2b:94A, tRNA:ser2b, tRNA:S2b, tRNA:S2b:94A, CR31162, tRNA[[Ser]], chr3R.trna45-SerGCT, tRNA-Ser-GCT-2-4, tRNA:Ser-GCT-2-4, tRNA:CR31162, AGC" - CR31162 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0027135 l(3)89ABa lethal (3) 89ABa http://flybase.org/reports/FBgn0027135 - gene - - - l(3)89ABa - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0046326 ms(2)38ABa ms(2)38ABa http://flybase.org/reports/FBgn0046326 gene - - - "ms in 38A/B, ms(2)38ABa" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0052358 tRNA:Leu-CAG-1-2 transfer RNA:Leucine-CAG 1-2 http://flybase.org/reports/FBgn0052358 tRNA_gene CUG codon-amino acid adaptor activity ; GO:0033420 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033420 cytosol ; GO:0005829 | inferred by curator from GO:0033420 "AE002602.trna10-LeuCAG, tRNA:L:CAG:AE002602-f, CR32358, chr3L.trna44-LeuCAG, tRNA-Leu-CAG-1-2, tRNA:Leu-CAG-1-2, tRNA:CR32358, CUG" - CR32358 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266680 lncRNA:CR45170 - http://flybase.org/reports/FBgn0266680 non_protein_coding_gene - - - CR45170 - CR45170 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0003026 ovi ovioculus http://flybase.org/reports/FBgn0003026 - gene - - - ovi - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive,male sterile,viable,male,reduced" "egg,wing" FBgn0001131 gr gracile http://flybase.org/reports/FBgn0001131 - gene - - - gr - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,male sterile,viable,poor" "wing,adult abdomen" FBgn0035692 Sf3b6 Splicing factor 3b subunit 6 http://flybase.org/reports/FBgn0035692 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from biological aspect of ancestor with PANTHER:PTN001765154" U12-type spliceosomal complex ; GO:0005689 | inferred from biological aspect of ancestor with PANTHER:PTN001765154 precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay U2 snRNP ; GO:0005686 | colocalizes_with inferred from direct assay U2-type spliceosomal complex ; GO:0005684 | inferred from biological aspect of ancestor with PANTHER:PTN001765154 "cg13298, CG13298, Sf3b6, SF3B6" "IPR000504:RNA recognition motif domain, IPR034150:SF3B14, RNA recognition motif" CG13298 27-Aug-18 DroID_v2018_08 Drer\sf3b6 Scer\IST3 Cele\C50D2.5 Xtro\sf3b6 Mmus\Sf3b6 Hsap\SF3B6 "visible,lethal,neuroanatomy defective,partially lethal - majority die" "wing,wing vein,ectopic,ganglion mother cell,mesothoracic tergum" DRSC09972 I 6.73025579 1.418457494 1.060828269 0.377725373 -1.187746024 -0.706984776 FBgn0035050 SiaT Sialyltransferase http://flybase.org/reports/FBgn0035050 protein_coding_gene "sialyltransferase activity ; GO:0008373 | inferred from direct assay beta-galactoside alpha-2,6-sialyltransferase activity ; GO:0003835 | inferred from direct assay" neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype protein N-linked glycosylation via asparagine ; GO:0018279 | inferred from biological aspect of ancestor with PANTHER:PTN000346035 oligosaccharide metabolic process ; GO:0009311 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay "D.SiaT, CG4871, dSiaT, DmPST, ST6Gal, DSiaT, D.SialT, DmSialT, SialT, dST6Gal I" IPR001675:Glycosyl transferase family 29 CG4871 27-Aug-18 DroID_v2018_08 "Drer\st8sia6, Drer\st8sia1, Drer\st3gal2, Drer\st6galnac5b, Drer\st3gal5, Drer\st3gal1l2, Drer\st6galnac3, Drer\st3gal3a, Drer\st6gal2b, Drer\st3gal8, Drer\st3gal1l3, Drer\st8sia7.1, Drer\st8sia5, Drer\st6gal1, Drer\st6galnac1.1, Drer\st3gal7, Drer\st3gal1, Drer\st8sia2, Drer\st6galnac, Drer\st6galnac4, Drer\st8sia4, Drer\st6galnac1.2, Drer\st6galnac6, Drer\st6galnac5a, Drer\st3gal4, Drer\st3gal3b, Drer\st8sia3, Drer\st3gal1l, Drer\st8sia7.1p, Drer\LOC100334439, Drer\st6gal2a" - Cele\Y94H6A.10 "Xtro\st6galnac4, Xtro\st3gal2.1, Xtro\st3gal5, Xtro\st6galnac2, Xtro\st6gal2, Xtro\st3gal4, Xtro\st3gal1, Xtro\st8sia4, Xtro\st6galnac5, Xtro\st8sia6, Xtro\st3gal2.2, Xtro\st8sia2, Xtro\st6galnac6, Xtro\st8sia1, Xtro\st6galnac3, Xtro\st8sia3, Xtro\st3gal3, Xtro\st6gal1, Xtro\st3gal6" "Mmus\St6galnac6, Mmus\St8sia2, Mmus\St6gal2, Mmus\St6galnac2, Mmus\St3gal1, Mmus\St6galnac5, Mmus\St6galnac3, Mmus\St8sia1, Mmus\St8sia6, Mmus\St3gal2, Mmus\St3gal4, Mmus\St6galnac4, Mmus\St6galnac1, Mmus\St3gal6, Mmus\St3gal5, Mmus\St8sia5, Mmus\St3gal3, Mmus\St8sia3, Mmus\St8sia4, Mmus\St6gal1" "Hsap\ST3GAL3, Hsap\ST6GALNAC6, Hsap\ST6GALNAC2, Hsap\ST8SIA2, Hsap\ST3GAL6, Hsap\ST8SIA4, Hsap\ST8SIA6, Hsap\ST6GALNAC1, Hsap\ST3GAL1, Hsap\ST6GALNAC4, Hsap\ST6GALNAC3, Hsap\ST6GAL2, Hsap\ST3GAL2, Hsap\ST8SIA5, Hsap\ST6GALNAC5, Hsap\ST8SIA3, Hsap\ST6GAL1, Hsap\ST8SIA1, Hsap\ST3GAL5, Hsap\ST3GAL4" "viable,fertile,short lived,locomotor behavior defective,bang sensitive,paralytic,heat sensitive,neuroanatomy defective,neurophysiology defective,chemical resistant,recessive" "embryonic/larval neuromuscular junction,NMJ bouton" FBgn0015016 Bora-Bora Bora-Bora http://flybase.org/reports/FBgn0015016 - region - - - Bora-Bora - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263616 lncRNA:CR43625 - http://flybase.org/reports/FBgn0263616 non_protein_coding_gene - - - CR43625 - CR43625 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002144 l(2)K335 lethal (2) K335 http://flybase.org/reports/FBgn0002144 - gene - - - l(2)K335 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0037646 CAHbeta Carbonic anhydrase beta http://flybase.org/reports/FBgn0037646 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001765 zinc ion binding ; GO:0008270 | inferred from sequence model carbonate dehydratase activity ; GO:0004089 | inferred from direct assay one-carbon metabolic process ; GO:0006730 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay "DmBCA, CG11967, CAHbeta, Dmel_CG11967, beta-CA" IPR001765:Carbonic anhydrase CG11967 27-Aug-18 DroID_v2018_08 - Scer\NCE103 "Cele\bca-2, Cele\bca-1" - - - "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0051784 CG31784 - http://flybase.org/reports/FBgn0051784 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs05c10, CG31784" IPR025254:Domain of unknown function DUF4201 CG31784 27-Aug-18 DroID_v2018_08 Drer\ccdc96 Scer\SLK19 Cele\T11B7.1 - "Mmus\Ccdc96, Mmus\Spn" "Hsap\SPN, Hsap\CCDC96" "viable,fertile,visible" mesothoracic tergum FBgn0069178 mcl(2)Z3384 mcl(2)Z3384 http://flybase.org/reports/FBgn0069178 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(2)Z3384 - - 27-Aug-18 DroID_v2018_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0036414 nan nanchung http://flybase.org/reports/FBgn0036414 protein_coding_gene cation channel activity ; GO:0005261 | inferred from sequence or structural similarity with pyx calcium channel activity ; GO:0005262 | inferred from sequence or structural similarity calcium channel activity ; GO:0005262 | inferred from biological aspect of ancestor with PANTHER:PTN000832860 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005821 sensory perception of sound ; GO:0007605 | inferred from mutant phenotype response to humidity ; GO:0009270 | inferred from mutant phenotype cation transport ; GO:0006812 | inferred from sequence or structural similarity with pyx detection of mechanical stimulus involved in sensory perception ; GO:0050974 | inferred from mutant phenotype response to auditory stimulus ; GO:0010996 | inferred from direct assay startle response ; GO:0001964 | inferred from mutant phenotype detection of mechanical stimulus involved in sensory perception of touch ; GO:0050976 | inferred from mutant phenotype neuromuscular process controlling posture ; GO:0050884 | inferred from mutant phenotype calcium ion transport ; GO:0006816 | inferred from sequence or structural similarity adult walking behavior ; GO:0007628 | inferred from mutant phenotype negative gravitaxis ; GO:0048060 | inferred from mutant phenotype integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000061616 cation channel complex ; GO:0034703 | inferred from sequence or structural similarity with pyx "TRPV, OCR, CT18317, CG5842, nan, Nan, DmNan, NAN" "IPR002110:Ankyrin repeat, IPR005821:Ion transport domain, IPR020683:Ankyrin repeat-containing domain, IPR024862:Transient receptor potential cation channel subfamily V" CG5842 27-Aug-18 DroID_v2018_08 "Drer\trpv4, Drer\trpv1, Drer\trpv6" Scer\YVC1 "Cele\ocr-2, Cele\ocr-1, Cele\ocr-3, Cele\ocr-4" "Xtro\trpv3, Xtro\trpv2, Xtro\trpv4, Xtro\trpv1" "Mmus\Trpv5, Mmus\Trpv4, Mmus\Trpv6, Mmus\Trpv3, Mmus\Trpv2, Mmus\Trpv1" "Hsap\TRPV6, Hsap\TRPV5, Hsap\TRPV1, Hsap\TRPV2, Hsap\TRPV3, Hsap\TRPV4" "courtship behavior defective,recessive,viable,uncoordinated,auditory perception defective,neurophysiology defective,behavior defective,locomotor behavior defective,gravitaxis defective,lethal" Johnston organ neuron FBgn0029058 l(1)G0435 lethal (1) G0435 http://flybase.org/reports/FBgn0029058 gene - - - l(1)G0435 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0263467 snoRNA:nop5-x16-a - http://flybase.org/reports/FBgn0263467 snoRNA_gene - - - "snoRNA:nop5-x16-a, snoRNA:nop_x16-a, snoCD_05" - CR43582 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0082926 snoRNA:Me28S-U1848 snoRNA:Me28S-U1848 http://flybase.org/reports/FBgn0082926 snoRNA_gene - - - "snoRNA:Me28S-U1848, Me28S-Um1848, Me28s-U1848, CR34535" - CR34535 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001422 l(1)6Df lethal (1) 6Df http://flybase.org/reports/FBgn0001422 - gene - - - l(1)6Df - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0267557 lncRNA:CR45897 - http://flybase.org/reports/FBgn0267557 non_protein_coding_gene - - - CR45897 - CR45897 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0025628 CG4199 - http://flybase.org/reports/FBgn0025628 - protein_coding_gene "2 iron, 2 sulfur cluster binding ; GO:0051537 | inferred from electronic annotation with InterPro:IPR017941 flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR016156 oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR016156, InterPro:IPR017941, InterPro:IPR023753" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR004099, InterPro:IPR016156, InterPro:IPR017941, InterPro:IPR023753" - "CG4199, 143005_at, EG:22E5.5" "IPR023753:FAD/NAD(P)-binding domain, IPR016156:FAD/NAD-linked reductase, dimerisation domain, IPR017941:Rieske [2Fe-2S] iron-sulphur domain" CG4199 27-Aug-18 DroID_v2018_08 "Drer\aifm4, Drer\aifm2, Drer\aifm3, Drer\aifm5" Scer\AIF1 Cele\F20D6.11 "Xtro\aifm3, Xtro\aifm2, Xtro\LOC100498581" Mmus\Aifm3 Hsap\AIFM3 "viable,fertile" FBgn0003991 vss variable size and shape http://flybase.org/reports/FBgn0003991 - gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "vss-1, vss" - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,maternal effect" egg FBgn0067734 l(1)G0463 lethal (1) G0463 http://flybase.org/reports/FBgn0067734 gene - - - l(1)G0463 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0262068 EG56 - http://flybase.org/reports/FBgn0262068 gene - - - EG56 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0266829 lncRNA:CR45291 - http://flybase.org/reports/FBgn0266829 non_protein_coding_gene - - - CR45291 - CR45291 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0082942 snoRNA:Me28S-A982b snoRNA:Me28S-A982b http://flybase.org/reports/FBgn0082942 snoRNA_gene - - - "snoRNA:Me28S-A982b, Me28S-Am982b, CR34528, DmSnR39/59b" - CR34528 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0003716 tkv thickveins http://flybase.org/reports/FBgn0003716 FBgn0010572 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000333, InterPro:IPR000719, InterPro:IPR003605, InterPro:IPR017441 receptor signaling protein serine/threonine kinase activity ; GO:0004702 | inferred from electronic annotation with InterPro:IPR000333 transforming growth factor beta binding ; GO:0050431 | inferred from physical interaction with dpp protein binding ; GO:0005515 | inferred from physical interaction with Dad transforming growth factor beta receptor activity, type I ; GO:0005025 | inferred from genetic interaction with dpp transforming growth factor beta receptor activity, type I ; GO:0005025 | non-traceable author statement transforming growth factor beta receptor activity, type I ; GO:0005025 | inferred from sequence or structural similarity protein kinase activity ; GO:0004672 | non-traceable author statement" "protein phosphorylation ; GO:0006468 |... electronic annotation with InterPro:IPR000719, InterPro:IPR003605, InterPro:IPR008271 <> negative regulation of salivary gland boundary specification ; GO:0045705 | traceable author statement <> imaginal disc-derived wing morphogenesis ; GO:0007476 |... mutant phenotype <> dorsal closure ; GO:0007391 |... mutant phenotype <> spectrosome organization ; GO:0030721 |... mutant phenotype <> imaginal disc-derived wing morphogenesis ; GO:0007476 |... mutant phenotype inferred from genetic interaction with dpp <> compound eye morphogenesis ; GO:0001745 |... mutant phenotype <> open tracheal system development ; GO:0007424 | non-traceable author statement <> transforming growth factor beta receptor signaling pathway ; GO:0007179 |... genetic interaction with dpp inferred from physical interaction with dpp <> anterior/posterior pattern specification, imaginal disc ; GO:0007448 |... mutant phenotype <> regulation of transcription from RNA polymerase II promoter ; GO:0006357 |... mutant phenotype <> protein phosphorylation ; GO:0006468 | non-traceable author statement <> transforming growth factor beta receptor signaling pathway ; GO:0007179 | non-traceable author statement <> regulation of cell differentiation ; GO:0045595 |... mutant phenotype <> neuromuscular synaptic transmission ; GO:0007274 |... mutant phenotype <> dorsal closure ; GO:0007391 | traceable author statement <> regulation of synaptic growth at neuromuscular junction ; GO:0008582 |... genetic interaction with Acsl <> transforming growth factor beta receptor signaling pathway involved in endodermal cell fate specification ; GO:0060799 |... mutant phenotype <> dorsal/ventral pattern formation ; GO:0009953 |... mutant phenotype inferred from genetic interaction with dpp <> heart development ; GO:0007507 | traceable author statement <> cell migration ; GO:0016477 |... mutant phenotype <> wing disc anterior/posterior pattern formation ; GO:0048100 |... mutant phenotype <> germ-line stem cell division ; GO:0042078 |... mutant phenotype <> regulation of imaginal disc growth ; GO:0045570 |... mutant phenotype <> open tracheal system development ; GO:0007424 |... mutant phenotype <> germ cell migration ; GO:0008354 |... mutant phenotype <> chorion-containing eggshell formation ; GO:0007304 |... genetic interaction with sax <> BMP signaling pathway ; GO:0030509 | traceable author statement <> morphogenesis of a branching structure ; GO:0001763 | non-traceable author statement <> positive regulation of synaptic growth at neuromuscular junction ; GO:0045887 |... mutant phenotype <> compound eye morphogenesis ; GO:0001745 | non-traceable author statement <> histoblast morphogenesis ; GO:0007488 |... mutant phenotype <> germ-line stem cell population maintenance ; GO:0030718 |... mutant phenotype <> anterior Malpighian tubule development ; GO:0061327 |... mutant phenotype <> decapentaplegic signaling pathway ; GO:0008101 |... mutant phenotype inferred from genetic interaction with dpp <> genital disc development ; GO:0035215 |... mutant phenotype <> open tracheal system development ; GO:0007424 | traceable author statement <> positive regulation of muscle organ development ; GO:0048636 |... mutant phenotype <> ovarian follicle cell development ; GO:0030707 | traceable author statement <> transforming growth factor beta receptor complex assembly ; GO:0007181 | non-traceable author statement <> cell elongation involved in imaginal disc-derived wing morphogenesis ; GO:0090254 |... mutant phenotype <> regulation of cell-cell adhesion ; GO:0022407 |... mutant phenotype <> negative regulation of gene expression ; GO:0010629 |... direct assay <> positive regulation of growth ; GO:0045927 |... mutant phenotype <> branched duct epithelial cell fate determination, open tracheal system ; GO:0046845 | traceable author statement" plasma membrane ; GO:0005886 | inferred from sequence or structural similarity cytoneme ; GO:0035230 | colocalizes_with inferred from direct assay early endosome ; GO:0005769 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with babo cytosol ; GO:0005829 | inferred from direct assay multivesicular body ; GO:0005771 | inferred from direct assay presynapse ; GO:0098793 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "tkv, Tkv, TKV, CG14026, Brk25D2, Brk25D1, dtfr, Atkv, l(2)04415, str, Brk25D, l(2)25Da, STK-A, Dtfr, Atr25D, tkv1, kv, TKV1, tkva" "IPR000472:Activin types I and II receptor domain, IPR000719:Protein kinase domain, IPR003605:GS domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR000333:Ser/Thr protein kinase, TGFB receptor" CG14026 27-Aug-18 DroID_v2018_08 "Drer\bmpr1ab, Drer\bmpr1bb, Drer\acvrl1, Drer\bmpr1ba, Drer\LOC100331105, Drer\acvr1l, Drer\acvr1ba, Drer\tgfbr1b, Drer\tgfbr1a, Drer\bmpr1aa, Drer\acvr1bb" - "Cele\daf-1, Cele\sma-6" "Xtro\bmpr1b, Xtro\acvr1c, Xtro\brsk1, Xtro\acvr1b, Xtro\bmpr1a, Xtro\tgfbr1, Xtro\acvr1" "Mmus\Acvrl1, Mmus\Tgfbr1, Mmus\Acvr1c, Mmus\Acvr1, Mmus\Bmpr1b, Mmus\Acvr1b, Mmus\Bmpr1a" "Hsap\ACVRL1, Hsap\BMPR1B, Hsap\ACVR1C, Hsap\BMPR1A, Hsap\ACVR1B, Hsap\ACVR1, Hsap\TGFBR1" " embryonic stage | stage 16 , larval stage , embryonic stage , embryonic stage | stage 9 , embryonic stage | stage 1-4 , embryonic stage | syncytial blastoderm , embryonic stage | stage 6 , embryonic stage | stage 6,7 , embryonic stage | stage 13-16 , embryonic stage | early , embryonic stage | stage 7 , embryonic stage | stage 5 , embryonic stage | 0-12hr , embryonic stage | stage 6-9 , embryonic stage | stage 3,4 , embryonic stage | stage >=12 , embryonic stage | stage 11-12 , embryonic stage | stage 11 , embryonic stage | stage 10 , larval stage | third instar , adult stage && oogenesis stage , embryonic stage | stage >12 , embryonic stage | stage 8 , embryonic stage | stage 6-12 , embryonic stage | cellular blastoderm , embryonic stage | stage 12-17 " " gastric caecum

, imaginal disc

, organism

, midgut chamber 4

, morphogenetic furrow

, embryonic/larval proventriculus

, midgut chamber 1

, mesoderm

,

ubiquitous , dorsal mesothoracic disc

, organism | pair rule

, mesoderm | ventral

, posterior embryonic/larval midgut

, eye-antennal disc

, midgut constriction 1

, ectoderm | lateral

, ventral thoracic disc

, ectoderm | dorsal

, embryonic/larval pharynx

,

dorsal ventral gradient , posterior midgut proper primordium

, tracheal pit

, anterior midgut proper primordium

, tracheal primordium

, embryonic/larval hindgut

, dorsal mesothoracic disc | restricted

, nurse cell

, anterior embryonic/larval midgut

, visceral mesoderm

, ventral neurogenic region

, epidermis | dorsal

, centripetally migrating follicle cell

,

pair rule , embryonic/larval midgut

" "visible,dominant,viable,fertile,lethal,recessive,partially,rescuable maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage,neuroanatomy defective,wild-type,semidominant,heat sensitive,germline clone,neurophysiology defective,mitotic cell cycle defective,somatic clone,lethal - all die before end of larval stage,some die during larval stage,cold sensitive,cell lethalcell lethal,partially lethal - majority die,cell autonomous,maternal effect,RU486 conditional,increased cell number,cell non-autonomous,lethal - all die before end of pupal stage,some die during pupal stage,increased cell death,female sterile,cell shape defective,hyperplasia,female limited,sterile,male limited,circadian rhythm defective" "submarginal cell,1st posterior cell,,wing,wing vein,embryonic/first instar larval cuticle,sex comb,ventral thoracic disc,leg,bouton,neuromuscular junction,dorsal appendage,egg operculum,filzkorper,embryonic dorsal epidermis,dorsal triple row,medial triple row,ventral triple row,embryo,eye,wing disc,scutum,embryonic head,abdominal segment,eye disc,embryonic epidermis,peripodial epithelium,wing margin,anterior crossvein,posterior crossvein,cephalopharyngeal skeleton,midgut constriction,gastric caecum,trachea,embryonic/larval dorsal branch 1,embryonic/larval dorsal branch 2,embryonic/larval dorsal branch 3,embryonic/larval dorsal branch 4,embryonic/larval dorsal branch 5,embryonic/larval dorsal branch 6,embryonic/larval dorsal branch 7,embryonic/larval dorsal branch 8,embryonic/larval dorsal branch 9,embryonic/larval dorsal branch 10,ganglionic branch 0,ganglionic branch 1,ganglionic branch 2,ganglionic branch 3,ganglionic branch 4,ganglionic branch 5,ganglionic branch 6,ganglionic branch 7,ganglionic branch 8,ganglionic branch 9,embryonic/larval lateral trunk,embryonic/larval dorsal branch,embryonic/larval trachea,ommatidium,female germline stem cell,male germline stem cell,embryonic/larval tracheal system,stage 13 embryo,stage 14 embryo,stage 15 embryo,amnioserosa,filamentous actin,secondary pigment cell,adult midgut precursor cell,presumptive embryonic/larval peripheral nervous system,ventral nerve cord,adult thorax,genital disc primordium,synapse,t-bar,embryonic/larval dorsal vessel,crystal cell,Malpighian tubule,dorsal closure embryo,morphogenetic furrow,testis,abdominal ventral denticle belt,telson,visceral mesoderm,presumptive embryonic salivary gland,histoblast,histoblast nest,crossvein,air sac primordium |,scutellar bristle,wing blade,abdomen,mesothoracic extracoxal depressor muscle 66,thoracic adult muscle precursor cell,NMJ bouton,adult brain,macrochaeta,sensory mother cell,tsh-Gal4-1,hs.PB,wing cell,btl.PS,dorsal trunk primordium,btl.B123,embryonic/larval neuromuscular junction,egg chamber,tracheocyte,embryonic/larval dorsal trunk,dorsal branch primordium,embryonic/larval muscle system,embryonic/larval visceral branch,tracheal pit,wing pouch,genitalia,analia,wing margin bristle,apoptotic amnioserosa,germline cell,hub cell,pericardial cell,mesoderm,epidermal cell,cell cycle,wing disc |,ovary,cystoblast,2nd posterior cell,dil cell,wing sensillum,wing | prepupal stage,haltere,mesothoracic tergum,retina | pupal stage P6,adherens junction,inter-ommatidial precursor cell,germarium,female germline cell" FBgn0267562 lncRNA:CR45902 - http://flybase.org/reports/FBgn0267562 non_protein_coding_gene - - - CR45902 - CR45902 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267254 CG45690 - http://flybase.org/reports/FBgn0267254 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG45690 - CG45690 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0050377 CG30377 - http://flybase.org/reports/FBgn0050377 protein_coding_gene - copper ion homeostasis ; GO:0055070 | inferred from mutant phenotype - "CG1918, CG14595, CG30377" - CG30377 27-Aug-18 DroID_v2018_08 Drer\cdk2ap2 - - "Xtro\cdk2ap2, Xtro\cdk2ap1" "Mmus\Cdk2ap1, Mmus\Cdk2ap2" "Hsap\CDK2AP2, Hsap\CDK2AP1" "viable,fertile,lethal" FBgn0022128 l(2)k06416 lethal (2) k06416 http://flybase.org/reports/FBgn0022128 - gene - - - l(2)k06416 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0011062 l(1)Q15 lethal (1) Q15 http://flybase.org/reports/FBgn0011062 FBgn0010210 gene - - - l(1)Q15 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0001540 l(1)14DEb lethal (1) 14DEb http://flybase.org/reports/FBgn0001540 - gene - - - "l(1)l, l(1)14DEb" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0062566 Mod(var)E69 Mod(var)E69 http://flybase.org/reports/FBgn0062566 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "E69, Mod(var)E69" - - 27-Aug-18 DroID_v2018_08 - - - - - - "enhancer of variegation,non-enhancer of variegation,non-suppressor of variegation,suppressor of variegation,viable" FBgn0019806 h::sc h::sc http://flybase.org/reports/FBgn0019806 - engineered_fusion_gene - - - h::sc - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031170 ABCA - http://flybase.org/reports/FBgn0031170 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR017871 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from biological aspect of ancestor with PANTHER:PTN000442469 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from sequence or structural similarity with UniProtKB:O94911" transport ; GO:0006810 | inferred from sequence or structural similarity with UniProtKB:O94911 lipid transport ; GO:0006869 | inferred from biological aspect of ancestor with PANTHER:PTN000442469 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with UniProtKB:Q9BZC7 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000442469 CG1718 "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR017871:ABC transporter, conserved site, IPR026082:ABC transporter A, ABCA" CG1718 27-Aug-18 DroID_v2018_08 "Drer\abch1, Drer\abca3b, Drer\abca12, Drer\abca1a, Drer\abca1b, Drer\abca5, Drer\abca2" "Scer\PDR18, Scer\PDR15, Scer\CAF16, Scer\PDR5, Scer\YOL075C, Scer\PDR10, Scer\SNQ2, Scer\PDR11, Scer\AUS1, Scer\PDR12" "Cele\abt-2, Cele\abt-4, Cele\ced-7, Cele\abt-5" "Xtro\abca2, Xtro\abca1, Xtro\abca3, Xtro\abca9, Xtro\abca8, Xtro\abca10, Xtro\abca4" "Mmus\Abca3, Mmus\Abca17, Mmus\Abca15, Mmus\Abca13, Mmus\Abca6, Mmus\Abca4, Mmus\Abca5, Mmus\Abca8b, Mmus\Abca9, Mmus\Abca1, Mmus\Abca7, Mmus\Abca8a, Mmus\Abca12, Mmus\Abca2, Mmus\Abca16, Mmus\Abca14" "Hsap\ABCA6, Hsap\ABCA10, Hsap\ABCA3, Hsap\ABCA7, Hsap\ABCA1, Hsap\ABCA2, Hsap\ABCA8, Hsap\ABCA5, Hsap\ABCA9, Hsap\ABCA4, Hsap\ABCA13, Hsap\ABCA12" viable DRSC20546 K 0.229437717 0.315420842 0.25940021 0.91173629 -0.208019204 -1.509490163 FBgn0013724 Raf::tor phl::tor http://flybase.org/reports/FBgn0013724 - engineered_fusion_gene - - - "raf, sev-raf, phl::tor, Raf::tor" - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,dominant" "ommatidium,photoreceptor cell R7,supernumerary,eye,ectopic,cone cell,photoreceptor cell,abdomen,eye disc,somatic clone" FBgn0039489 CG5880 - http://flybase.org/reports/FBgn0039489 protein_coding_gene protein-cysteine S-palmitoyltransferase activity ; GO:0019706 | inferred from sequence or structural similarity with SGD:S000004236 protein palmitoylation ; GO:0018345 | inferred from sequence or structural similarity with SGD:S000004236 Golgi apparatus ; GO:0005794 | inferred from direct assay CG5880 "IPR001594:Palmitoyltransferase, DHHC domain" CG5880 27-Aug-18 DroID_v2018_08 "Drer\zdhhc16b, Drer\zdhhc16a" "Scer\PFA3, Scer\SWF1" "Cele\dhhc-9, Cele\dhhc-12" Xtro\zdhhc16 Mmus\Zdhhc16 Hsap\ZDHHC16 "lethal,partially lethal - majority die,some die during pupal stage" FBgn0266357 lncRNA:CR45005 - http://flybase.org/reports/FBgn0266357 non_protein_coding_gene - - - CR45005 - CR45005 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260084 2L3179 - http://flybase.org/reports/FBgn0260084 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L3179 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" "embryonic/larval dorsal trunk,somatic clone,dorsal air sac primordium" FBgn0264987 lncRNA:CR44138 - http://flybase.org/reports/FBgn0264987 non_protein_coding_gene - - - CR44138 - CR44138 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0024653 l(2)k08307 lethal (2) k08307 http://flybase.org/reports/FBgn0024653 - gene - - - "83/7, l(2)k08307" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0032089 Rcd-1r Rcd-1 related http://flybase.org/reports/FBgn0032089 protein_coding_gene molecular_function ; GO:0003674 | no biological data available spermatogenesis ; GO:0007283 | inferred from expression pattern negative regulation of translation ; GO:0017148 | inferred from biological aspect of ancestor with PANTHER:PTN000262555 reproductive process ; GO:0022414 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype CCR4-NOT core complex ; GO:0030015 | inferred from biological aspect of ancestor with PANTHER:PTN000262555 cytoplasmic mRNA processing body ; GO:0000932 | inferred from biological aspect of ancestor with PANTHER:PTN000262555 nucleus ; GO:0005634 | inferred from direct assay "CG9573, Drcd-1r, Rcd-1r, Zeus" "IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical" CG9573 27-Aug-18 DroID_v2018_08 Drer\rqcd1 Scer\CAF40 Cele\ntl-9 Xtro\rqcd1 Mmus\Cnot9 Hsap\CNOT9 "male semi-sterile,female fertile,male semi-fertile" testis FBgn0021995 Rs1 Rs1 http://flybase.org/reports/FBgn0021995 FBgn0028477 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR011545 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from sequence or structural similarity with SGD:S000003931 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 RNA secondary structure unwinding ; GO:0010501 | inferred from biological aspect of ancestor with PANTHER:PTN000618218 ribosome biogenesis ; GO:0042254 | non-traceable author statement positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype - "153844_at, DmRH21, cg2173, l(2)k09514, Drs1, CG2173, BcDNA:GM05306, Rs1" "IPR000629:ATP-dependent RNA helicase DEAD-box, conserved site, IPR001650:Helicase, C-terminal, IPR011545:DEAD/DEAH box helicase domain, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR014014:RNA helicase, DEAD-box type, Q motif, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG2173 27-Aug-18 DroID_v2018_08 Drer\ddx27 Scer\DRS1 Cele\ddx-27 Xtro\ddx27 Mmus\Ddx27 Hsap\DDX27 "lethal,recessive,viable,visible" mesothoracic tergum DRSC05945 E -1.395678537 0.720694061 1.543172694 -0.124592027 -0.063330169 -0.169392667 FBgn0024678 l(1)LefEM3 lethal (1) LefEM3 http://flybase.org/reports/FBgn0024678 - gene - - - "EM3, l(1)LefEM3" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265084 CG44195 - http://flybase.org/reports/FBgn0265084 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44195 - CG44195 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267990 lncRNA:CR46257 - http://flybase.org/reports/FBgn0267990 non_protein_coding_gene - - - CR46257 - CR46257 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267722 asRNA:CR46055 - http://flybase.org/reports/FBgn0267722 non_protein_coding_gene - - - CR46055 - CR46055 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0052432 CG32432 - http://flybase.org/reports/FBgn0052432 protein_coding_gene - - - "CG13257, CG13256, FBgn0037032, CG3116, CG32432" "IPR000859:CUB domain, IPR023415:Low-density lipoprotein (LDL) receptor class A, conserved site, IPR002172:Low-density lipoprotein (LDL) receptor class A repeat" CG32432 27-Aug-18 DroID_v2018_08 "Drer\ston2, Drer\ap4m1" - Cele\lev-10 - "Mmus\Ston1, Mmus\Ap4m1, Mmus\Ston2" "Hsap\STON1, Hsap\AP4M1, Hsap\STON2" "viable,fertile" FBgn0260027 CG42495 - http://flybase.org/reports/FBgn0260027 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42495 - CG42495 27-Aug-18 DroID_v2018_08 Drer\LOC100537949 - Cele\F40F8.3 - Mmus\Tmem42 Hsap\TMEM42 FBgn0034770 Obp58d Odorant-binding protein 58d http://flybase.org/reports/FBgn0034770 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 extracellular region ; GO:0005576 | inferred from sequence model "CG13519, Obp58d, DmelObp58d" IPR006170:Pheromone/general odorant binding protein CG13519 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible" trichogen cell FBgn0083966 CG34130 - http://flybase.org/reports/FBgn0083966 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254 molecular_function ; GO:0003674 | no biological data available proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "CG6069, SPH192, CG34130" "IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan" CG34130 27-Aug-18 DroID_v2018_08 "Drer\tmprss9, Drer\zgc:55888, Drer\st14a, Drer\zmp:0000001114" - - - "Mmus\St14, Mmus\Gzma, Mmus\Gzmm, Mmus\Tmprss13" "Hsap\TMPRSS13, Hsap\GZMM, Hsap\ST14, Hsap\GZMA" viable FBgn0033689 CG18342 - http://flybase.org/reports/FBgn0033689 protein_coding_gene - - - CG18342 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002994 olfQ olfactory Q http://flybase.org/reports/FBgn0002994 - gene - - - olfQ - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0015365 biz bizarre http://flybase.org/reports/FBgn0015365 - gene - thermosensory behavior ; GO:0040040 | inferred from mutant phenotype - "SB8, biz" - - 27-Aug-18 DroID_v2018_08 - - - - - - "hypoactive,behavior defective" FBgn0044511 mRpS21 mitochondrial ribosomal protein S21 http://flybase.org/reports/FBgn0044511 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:P82921 translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:P82921 mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:P82921 mitochondrial small ribosomal subunit ; GO:0005763 | traceable author statement "MRP-S21, BcDNA:RE23482, CG32854, MrpS21, mRpS21" IPR001911:Ribosomal protein S21 CG32854 27-Aug-18 DroID_v2018_08 Drer\mrps21 - Cele\mrps-21 Xtro\mrps21 Mmus\Mrps21 Hsap\MRPS21 "viable,visible" trichogen cell DRSC21357 E -0.426059269 0.32651795 0.308568485 -1.556125223 -0.104345499 0.23009066 FBgn0035009 CG16837 - http://flybase.org/reports/FBgn0035009 protein_coding_gene "dynein intermediate chain binding ; GO:0045505 | inferred from biological aspect of ancestor with PANTHER:PTN000081506 ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity" microtubule-based movement ; GO:0007018 | inferred from biological aspect of ancestor with PANTHER:PTN000081506 microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity microtubule associated complex ; GO:0005875 | inferred from direct assay dynein complex ; GO:0030286 | inferred from sequence or structural similarity dynein complex ; GO:0030286 | inferred from biological aspect of ancestor with PANTHER:PTN000081506 CG16837 IPR004942:Roadblock/LAMTOR2 domain CG16837 27-Aug-18 DroID_v2018_08 "Drer\dynlrb1, Drer\si:ch211-147k9.8" - Cele\dyrb-1 "Xtro\dynlrb2, Xtro\dynlrb1" "Mmus\Dynlrb2, Mmus\Dynlrb1" "Hsap\DYNLRB2, Hsap\DYNLRB1" viable DRSC04283 E 0.340083742 -0.00982863 0.106799039 -1.588708857 -0.165432031 0.560633672 FBgn0002991 olfB olfactory B http://flybase.org/reports/FBgn0002991 - gene - - - olfB - - 27-Aug-18 DroID_v2018_08 - - - - - - "fertile,smell perception defective,recessive,heat sensitive,viable" FBgn0030066 CG1885 - http://flybase.org/reports/FBgn0030066 protein_coding_gene uroporphyrinogen-III synthase activity ; GO:0004852 | inferred from biological aspect of ancestor with PANTHER:PTN000273374 uroporphyrinogen III biosynthetic process ; GO:0006780 | inferred from biological aspect of ancestor with PANTHER:PTN000273374 heme biosynthetic process ; GO:0006783 | inferred from biological aspect of ancestor with PANTHER:PTN000273374 - CG1885 "IPR003754:Tetrapyrrole biosynthesis, uroporphyrinogen III synthase" CG1885 27-Aug-18 DroID_v2018_08 Drer\uros Scer\HEM4 - Xtro\uros Mmus\Uros Hsap\UROS FBgn0035829 HP4 Heterochromatin protein 4 http://flybase.org/reports/FBgn0035829 protein_coding_gene - chromatin organization ; GO:0006325 | inferred from mutant phenotype "polytene chromosome ; GO:0005700 | inferred from direct assay polytene chromosome chromocenter ; GO:0005701 | inferred from direct assay nuclear heterochromatin ; GO:0005720 | inferred from direct assay polytene chromosome, telomeric region ; GO:0035012 | inferred from direct assay chromocenter ; GO:0010369 | inferred from direct assay heterochromatin ; GO:0000792 | inferred from direct assay polytene chromosome band ; GO:0005704 | inferred from direct assay nucleolus ; GO:0005730 | inferred from direct assay" "BcDNA:GM01628, CG8044, hip, HP4, Hip" - CG8044 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile,suppressor of variegation,dominant" FBgn0051279 CG31279 - http://flybase.org/reports/FBgn0051279 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG31279 - CG31279 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031053 CG14223 - http://flybase.org/reports/FBgn0031053 protein_coding_gene - - - CG14223 "IPR015943:WD40/YVTN repeat-like-containing domain, IPR029201:Jiraiya" CG14223 27-Aug-18 DroID_v2018_08 - - - - - - DRSC24816 K -0.111555407 -0.194712974 0.089880742 -0.097187759 1.630112523 0.81189103 FBgn0283478 und uninitiated http://flybase.org/reports/FBgn0283478 protein_coding_gene aminopeptidase activity ; GO:0004177 | inferred from electronic annotation with InterPro:IPR002468 metalloexopeptidase activity ; GO:0008235 | inferred from electronic annotation with InterPro:IPR002468 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR002468 - "MAP2, DMAP2, CG4008, und, p67" "IPR000994:Peptidase M24, IPR001714:Peptidase M24, methionine aminopeptidase, IPR002468:Peptidase M24A, methionine aminopeptidase, subfamily 2, IPR011991:Winged helix-turn-helix DNA-binding domain" CG4008 27-Aug-18 DroID_v2018_08 "Drer\metap2a, Drer\metap2b" Scer\MAP2 "Cele\T27A8.3, Cele\map-2, Cele\F53B6.5" Xtro\metap2 Mmus\Metap2 Hsap\METAP2 "partially lethal - majority die,recessive,visible,planar polarity defective,wild-type,viable" "eye,wing,anterior,ommatidium,eye photoreceptor cell,ventral,wing vein L5,trichogen cell" FBgn0041582 tamo tamo http://flybase.org/reports/FBgn0041582 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001876 protein binding ; GO:0005515 | inferred from physical interaction with msl-1 inferred from physical interaction with mbo inferred from physical interaction with dl Ran GTPase binding ; GO:0008536 | inferred from physical interaction with Ran inferred from physical interaction with Ran-like multicellular organism development ; GO:0007275 | inferred from direct assay protein transport ; GO:0015031 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay "CG4057, 60B, tamo" "IPR001876:Zinc finger, RanBP2-type, IPR029746:Protein tamozhennic, IPR018997:PUB domain" CG4057 27-Aug-18 DroID_v2018_08 "Drer\spata2l, Drer\spata2, Drer\si:ch211-189a15.5" - - Xtro\spata2 "Mmus\Spata2l, Mmus\Spata2" "Hsap\SPATA2, Hsap\SPATA2L" "female sterile,lethal,partially,viable" "embryonic dorsal epidermis,filzkorper,denticle belt,egg chamber" FBgn0010278 Ssrp Structure specific recognition protein http://flybase.org/reports/FBgn0010278 FBgn0005644 protein_coding_gene nucleosome binding ; GO:0031491 | inferred from direct assay protein self-association ; GO:0043621 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Trl nucleosomal DNA binding ; GO:0031492 | inferred from direct assay regulation of chromatin assembly or disassembly ; GO:0001672 | inferred from mutant phenotype regulation of DNA binding ; GO:0051101 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype negative regulation of protein phosphorylation ; GO:0001933 | inferred from mutant phenotype positive regulation of actin filament polymerization ; GO:0030838 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype FACT complex ; GO:0035101 | inferred from direct assay FACT complex ; GO:0035101 | traceable author statement nucleolus ; GO:0005730 | inferred from direct assay "ssrp, SSRP1, dSSRP1, SSRP, dSSRP, DssRP, Cf5, CG4817, Ssrp, dSsrp" "IPR013719:Domain of unknown function DUF1747, IPR024954:SSRP1 domain, IPR000969:Structure-specific recognition protein, IPR009071:High mobility group box domain, IPR011993:PH domain-like" CG4817 27-Aug-18 DroID_v2018_08 "Drer\ssrp1b, Drer\ssrp1a" "Scer\NHP6A, Scer\RTT106, Scer\NHP6B, Scer\POB3" "Cele\hmg-4, Cele\hmg-1.2, Cele\hmg-3" Xtro\ssrp1 Mmus\Ssrp1 Hsap\SSRP1 " oogenesis stage && adult stage | female , adult stage && oogenesis stage " " ovary

, nurse cell

" "lethal - all die during pharate adult stage,lethal,neuroanatomy defective,visible,lethal - all die before end of pupal stage,some die during pupal stage" "eye,antenna,head capsule,eye-antennal disc,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC04658 IE -3.67644009 -3.621707834 -1.920941941 -2.251911414 0.210811842 -0.555188344 FBgn0030945 Ing3 "Inhibitor of growth family, member 3" http://flybase.org/reports/FBgn0030945 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001965 histone acetyltransferase activity ; GO:0004402 | contributes_to inferred from direct assay histone exchange ; GO:0043486 | inferred from direct assay histone acetylation ; GO:0016573 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay histone acetyltransferase complex ; GO:0000123 | inferred from physical interaction with pont NuA4 histone acetyltransferase complex ; GO:0035267 | inferred from direct assay "dIng3~, dIng3, CG6632, Ing3, ING3" "IPR001965:Zinc finger, PHD-type, IPR011011:Zinc finger, FYVE/PHD-type, IPR019786:Zinc finger, PHD-type, conserved site, IPR019787:Zinc finger, PHD-finger, IPR024610:Inhibitor of growth protein, N-terminal histone-binding, IPR028651:ING family, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG6632 27-Aug-18 DroID_v2018_08 "Drer\ing2, Drer\taf3, Drer\ing1, Drer\ing5a, Drer\ing5b, Drer\ing3, Drer\ing4" "Scer\YNG1, Scer\YNG2, Scer\PHO23" "Cele\Y43H11AL.1, Cele\ing-3, Cele\lsy-13" "Xtro\ing5, Xtro\ing3, Xtro\taf3, Xtro\ing2, Xtro\ing1" "Mmus\Ing2, Mmus\Taf3, Mmus\Ing5, Mmus\Ing1, Mmus\Ing3, Mmus\Ing4" "Hsap\ING1, Hsap\TAF3, Hsap\ING5, Hsap\ING4, Hsap\ING3, Hsap\ING2" "viable,fertile" DRSC27959 EK -0.20937189 0.121195181 2.591371594 -0.420961652 -1.723706771 -1.52375965 FBgn0065566 l(2)SH0978 lethal (2) SH0978 http://flybase.org/reports/FBgn0065566 gene - - - "l(2)SH0978, l(2)SH2 0978" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0041123 l(2)45Bd lethal (2) 45Bd http://flybase.org/reports/FBgn0041123 gene - - - l(2)45Bd - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0000027 acj3 abnormal chemosensory jump 3 http://flybase.org/reports/FBgn0000027 - gene molecular_function ; GO:0003674 | no biological data available chemosensory jump behavior ; GO:0007636 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available acj3 - - 27-Aug-18 DroID_v2018_08 - - - - - - "chemosensitive behavior defective,recessive" FBgn0004593 Eig71Ef Ecdysone-induced gene 71Ef http://flybase.org/reports/FBgn0004593 - protein_coding_gene - autophagic cell death ; GO:0048102 | inferred from expression pattern defense response to bacterium ; GO:0042742 | inferred from sequence or structural similarity with MGI:MGI:94880 salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern extracellular region ; GO:0005576 | inferred from sequence model "L71, L71-5, V, gene V, gene-V, CG7599, Eig71Ef, EIG71-EF" IPR003475:Insect protein of unknown function CG7599 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259919 Csp::nSyb - http://flybase.org/reports/FBgn0259919 engineered_fusion_gene - - - "Csp::n-syb, Csp::n-Syb, Csp::nSyb" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0052699 LPCAT Lysophosphatidylcholine acyltransferase http://flybase.org/reports/FBgn0052699 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 lysophospholipid acyltransferase activity ; GO:0071617 | inferred from mutant phenotype 1-acylglycerophosphocholine O-acyltransferase activity ; GO:0047184 | inferred from sequence or structural similarity with UniProtKB:Q3TFD2 phospholipid biosynthetic process ; GO:0008654 | inferred from sequence or structural similarity with UniProtKB:Q3TFD2 lipid modification ; GO:0030258 | inferred from mutant phenotype Golgi apparatus ; GO:0005794 | inferred from sequence or structural similarity with UniProtKB:Q3TFD2 lipid particle ; GO:0005811 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with UniProtKB:Q3TFD2 "CG2996, tok-like, CT7882, CG15318, CG18535, LPCAT, CG32699, LPCAT1/2" "IPR002123:Phospholipid/glycerol acyltransferase, IPR011992:EF-hand domain pair, IPR002048:EF-hand domain" CG32699 27-Aug-18 DroID_v2018_08 "Drer\LOC101884921, Drer\lpcat1, Drer\LOC100536112, Drer\lpcat2, Drer\lpcat4" - Cele\acl-8 "Xtro\lpcat4, Xtro\lpcat2, Xtro\lpcat1" "Mmus\Lpcat4, Mmus\Lpcat2, Mmus\Lpcat2b, Mmus\Lpcat1" "Hsap\LPCAT1, Hsap\LPCAT4, Hsap\LPCAT2" "viable,fertile,visible" mesothoracic tergum FBgn0030670 Pis Phosphatidylinositol synthase http://flybase.org/reports/FBgn0030670 protein_coding_gene CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity ; GO:0003881 | inferred from direct assay basement membrane organization ; GO:0071711 | inferred from mutant phenotype phosphatidylinositol biosynthetic process ; GO:0006661 | inferred from biological aspect of ancestor with PANTHER:PTN000394714 phototransduction ; GO:0007602 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR000462 Golgi apparatus ; GO:0005794 | inferred from biological aspect of ancestor with PANTHER:PTN000394714 "anon-WO02059370.38, Pis, dpis, dPIS, CG9245, dPis" "IPR000462:CDP-alcohol phosphatidyltransferase, IPR014387:CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote" CG9245 27-Aug-18 DroID_v2018_08 Drer\cdipt Scer\PIS1 Cele\pisy-1 Xtro\cdipt Mmus\Cdipt Hsap\CDIPT "lethal - all die before end of embryonic stage,some die during embryonic stage,viable,heat sensitive,neurophysiology defective" "eye,somatic clone,eye photoreceptor cell,rhabdomere,rhabdomere, with Pishs.THsapMYC,rhabdomere, with Pis1" FBgn0002704 Me Moire http://flybase.org/reports/FBgn0002704 - gene - - - "Mo, Me" - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,dominant,lethal,recessive,eye color defective" "eye,pigment cell,macrochaeta" FBgn0053433 5SrRNA:CR33433 5SrRNA:CR33433 http://flybase.org/reports/FBgn0053433 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33433, 5SrRNA:CR33433" - CR33433 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031430 CG3528 - http://flybase.org/reports/FBgn0031430 protein_coding_gene - - - CG3528 IPR027887:Protein of unknown function DUF4464 CG3528 27-Aug-18 DroID_v2018_08 Drer\si:ch211-57h10.1 - - - Mmus\1700007G11Rik Hsap\C4orf22 FBgn0263615 lncRNA:CR43624 - http://flybase.org/reports/FBgn0263615 non_protein_coding_gene - - - CR43624 - CR43624 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051463 CG31463 - http://flybase.org/reports/FBgn0051463 protein_coding_gene - - - "CG11673, CG31463" - CG31463 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" FBgn0024625 l(3)63Db lethal (3) 63Db http://flybase.org/reports/FBgn0024625 - gene - - - "c.g.15, l(3)63Db" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0065820 l(2)SH0369 lethal (2) SH0369 http://flybase.org/reports/FBgn0065820 gene - - - "l(2)SH0369, l(2)SH2 0369" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0266675 lncRNA:CR45165 - http://flybase.org/reports/FBgn0266675 non_protein_coding_gene - - - CR45165 - CR45165 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001407 l(1)3Bb lethal (1) 3Bb http://flybase.org/reports/FBgn0001407 - gene - - - "zw-6, l(1)zw6, zw6, ZW-6, l(1)3Bb" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,rescuable maternal effect,partially lethal - majority die,female sterile" tergite FBgn0005379 fs(2)OW207 female sterile (2) OW207 http://flybase.org/reports/FBgn0005379 - gene - - - fs(2)OW207 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085797 CR41540 - http://flybase.org/reports/FBgn0085797 rRNA_gene - - - CR41540 - CR41540 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267935 lncRNA:CR46215 - http://flybase.org/reports/FBgn0267935 non_protein_coding_gene - - - "CR46215, lincRNA.604" - CR46215 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0003699 thl thick legs http://flybase.org/reports/FBgn0003699 - gene - - - thl - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,male fertile,viable,male,reduced,recessive,eye color defective,body color defective" "wing,leg,metathoracic leg,tibia,tarsal segment,pigment cell" FBgn0039427 CG5447 - http://flybase.org/reports/FBgn0039427 protein_coding_gene protein-cysteine S-palmitoyltransferase activity ; GO:0019706 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000327115 peptidyl-L-cysteine S-palmitoylation ; GO:0018230 | inferred from biological aspect of ancestor with PANTHER:PTN000327115 protein targeting to membrane ; GO:0006612 | inferred from biological aspect of ancestor with PANTHER:PTN000327115 protein localization to plasma membrane ; GO:0072659 | inferred from biological aspect of ancestor with PANTHER:PTN000327115 Golgi to plasma membrane protein transport ; GO:0043001 | inferred from sequence or structural similarity with HGNC:24876 intrinsic component of Golgi membrane ; GO:0031228 | inferred from sequence or structural similarity with HGNC:24876 palmitoyltransferase complex ; GO:0002178 | inferred from biological aspect of ancestor with PANTHER:PTN000327115 CG5447 IPR019383:Golgin subfamily A member 7/ERF4 CG5447 27-Aug-18 DroID_v2018_08 "Drer\golga7ba, Drer\golga7, Drer\golga7bb" Scer\SHR5 Cele\Y57G11C.33 "Xtro\golga7, Xtro\golga7b" "Mmus\Golga7b, Mmus\Golga7" "Hsap\GOLGA7, Hsap\GOLGA7B" "viable,fertile" FBgn0064156 mod(Fmr1) modifier of Fmr1 http://flybase.org/reports/FBgn0064156 gene - - - mod(Fmr1) - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0011450 l(3)neo6 lethal (3) neo6 http://flybase.org/reports/FBgn0011450 - gene - - - l(3)neo6 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0263116 5-HT1B 5-hydroxytryptamine (serotonin) receptor 1B http://flybase.org/reports/FBgn0263116 protein_coding_gene G-protein coupled serotonin receptor activity ; GO:0004993 | traceable author statement Gi/o-coupled serotonin receptor activity ; GO:0001586 | non-traceable author statement neurotransmitter receptor activity ; GO:0030594 | inferred from biological aspect of ancestor with PANTHER:PTN000664111 G-protein coupled serotonin receptor activity ; GO:0004993 | inferred from direct assay G-protein coupled serotonin receptor activity ; GO:0004993 | inferred from sequence or structural similarity G-protein coupled amine receptor activity ; GO:0008227 | inferred from sequence or structural similarity serotonin receptor signaling pathway ; GO:0007210 | inferred from direct assay adenylate cyclase-inhibiting serotonin receptor signaling pathway ; GO:0007198 | inferred from direct assay phospholipase C-activating serotonin receptor signaling pathway ; GO:0007208 | traceable author statement adenylate cyclase-inhibiting serotonin receptor signaling pathway ; GO:0007198 | traceable author statement serotonin receptor signaling pathway ; GO:0007210 | inferred from sequence or structural similarity entrainment of circadian clock ; GO:0009649 | inferred from mutant phenotype phospholipase C-activating serotonin receptor signaling pathway ; GO:0007208 | inferred from direct assay "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR017452 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity" "5-HT1B, CG30126, CG15113, Dm5HTdro2B, 5HT-dro2B, 5-HT[[1BDro]], 5-HT-dro2B, DRO2B, 5htdro2b, 5-HT[[dro2B]], 5-HT1BDro, 5HT-dro[[2B]], 5HT-R2B, d5-HT1B, 5HT1B, 5-HT[1B]Dro, 5-HT[[1B]], 5-HT[[1B]]Dro, 5-HT[[1B]]DRO, HT1B, 5HT1b" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG15113 27-Aug-18 DroID_v2018_08 "Drer\or137-3, Drer\htr1fb, Drer\LOC100330650, Drer\htr1ab, Drer\htr1d, Drer\or137-2, Drer\or135-1, Drer\or137-7, Drer\htr1b, Drer\htr5ab, Drer\si:dkeyp-3f10.14, Drer\or132-4, Drer\si:dkey-92k1.9, Drer\or137-8, Drer\or132-3, Drer\si:dkeyp-3f10.12, Drer\or136-1, Drer\or133-1, Drer\si:dkeyp-3f10.11, Drer\htr5aa, Drer\or132-5, Drer\or137-9, Drer\htr1aa, Drer\or132-1, Drer\adra2a, Drer\or134-1, Drer\or137-4, Drer\or132-2, Drer\or137-5, Drer\htr1e, Drer\or137-1, Drer\htr1fa" - "Cele\ser-7, Cele\octr-1, Cele\ser-4, Cele\ser-2" "Xtro\htr1b, Xtro\htr1f, Xtro\htr1a, Xtro\htr5a" "Mmus\Adra2a, Mmus\Htr1b, Mmus\Lpar2, Mmus\Htr1d, Mmus\Htr7, Mmus\Htr5b, Mmus\Htr5a, Mmus\Htr1a, Mmus\Htr1f" "Hsap\ADRA2A, Hsap\HTR1E, Hsap\HTR5A, Hsap\HTR1D, Hsap\HTR7, Hsap\HTR1F, Hsap\HTR1B, Hsap\HTR1A, Hsap\LPAR2" " embryonic stage | stage 16,17 " " bipolar dendrite neuron

, ventral midline

" FBgn0063381 snoRNA:Me28S-G3081a - http://flybase.org/reports/FBgn0063381 snoRNA_gene - - - "U31snoRNA, CR32887, snoRNA:Me28S-G3081a, Me28S-G3081a(U31), snoRNA:U31:54Ea, DmSnR67, Dm_28S.041" - CR32887 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259555 GG01052 - http://flybase.org/reports/FBgn0259555 gene - - - GG01052 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "unguis,leg,mesothoracic tergum,arista,eye,wing margin" FBgn0029936 CG4617 - http://flybase.org/reports/FBgn0029936 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG4617, CC28" IPR009071:High mobility group box domain CG4617 27-Aug-18 DroID_v2018_08 Drer\hmgxb4a "Scer\HMO1, Scer\IXR1" - Xtro\hmgxb4 "Mmus\A530032D15Rik, Mmus\Sp110, Mmus\Hmgxb4" "Hsap\HMGXB4, Hsap\SP140, Hsap\SP140L, Hsap\SP110" "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0003336 scp scooped http://flybase.org/reports/FBgn0003336 - gene - - - scp - - 27-Aug-18 DroID_v2018_08 - - - - - - visible wing FBgn0031723 CG7251 - http://flybase.org/reports/FBgn0031723 protein_coding_gene - - - "bs11h10.y1, anon-WO0140519.103, CG7251" - CG7251 27-Aug-18 DroID_v2018_08 "Drer\LOC103909961, Drer\zgc:153293" - - - Mmus\Ccdc34 Hsap\CCDC34 viable FBgn0036459 CG3349 - http://flybase.org/reports/FBgn0036459 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from sequence model CG3349 - CG3349 27-Aug-18 DroID_v2018_08 Drer\mccc2 Scer\NDC80 - - Mmus\Mccc2 Hsap\MCCC2 viable FBgn0039714 Zip99C Zinc/iron regulated transporter-related protein 99C http://flybase.org/reports/FBgn0039714 protein_coding_gene zinc ion transmembrane transporter activity ; GO:0005385 | inferred from biological aspect of ancestor with PANTHER:PTN000424313 zinc ion transmembrane transporter activity ; GO:0005385 | inferred by curator from GO:0016323 iron ion transmembrane transporter activity ; GO:0005381 | inferred from direct assay zinc II ion transmembrane transport ; GO:0071577 | inferred from biological aspect of ancestor with PANTHER:PTN000424313 multicellular organismal iron ion homeostasis ; GO:0060586 | inferred from mutant phenotype detoxification of zinc ion ; GO:0010312 | inferred from mutant phenotype iron ion transport ; GO:0006826 | inferred from mutant phenotype cellular zinc ion homeostasis ; GO:0006882 | inferred from biological aspect of ancestor with PANTHER:PTN000424313 basolateral plasma membrane ; GO:0016323 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from direct assay "CG7816, dZip99C, dZip13, Zip99C, cg7816, dZIP13" IPR003689:Zinc/iron permease CG7816 27-Aug-18 DroID_v2018_08 Drer\slc39a13 Scer\YKE4 "Cele\C14H10.1, Cele\hke-4.1, Cele\hke-4.2" Xtro\slc39a13 "Mmus\Slc39a7, Mmus\Slc39a13" "Hsap\SLC39A13, Hsap\SLC39A7" viable FBgn0265961 lncRNA:CR44748 - http://flybase.org/reports/FBgn0265961 non_protein_coding_gene - - - CR44748 - CR44748 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065978 iab-7E.s iab-7E.s http://flybase.org/reports/FBgn0065978 gene - - - "7E-s, iab-7E.s" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265368 lncRNA:CR44309 - http://flybase.org/reports/FBgn0265368 non_protein_coding_gene - - - "CR44309, lincRNA.24" - CR44309 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002381 l(3)93Ca lethal (3) 93Ca http://flybase.org/reports/FBgn0002381 - gene - - - "er6, l(3)er6, l(3)93Ca" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0030679 CG8206 - http://flybase.org/reports/FBgn0030679 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007853 chaperone binding ; GO:0051087 | inferred from biological aspect of ancestor with PANTHER:PTN000467874 protein folding ; GO:0006457 | inferred from biological aspect of ancestor with PANTHER:PTN000467874 protein stabilization ; GO:0050821 | inferred from biological aspect of ancestor with PANTHER:PTN000467874 protein import into mitochondrial matrix ; GO:0030150 | inferred from biological aspect of ancestor with PANTHER:PTN000467874 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000467874 CG8206 "IPR007853:Zinc finger, DNL-type, IPR024158:Mitochondrial import protein TIM15" CG8206 27-Aug-18 DroID_v2018_08 "Drer\card9, Drer\card11, Drer\dnlz, Drer\card14" Scer\ZIM17 Cele\F53A3.7 "Xtro\card9, Xtro\card14, Xtro\dnlz" "Mmus\Card10, Mmus\Card9, Mmus\Card14, Mmus\Card11, Mmus\Dnlz" "Hsap\CARD9, Hsap\CARD10, Hsap\CARD14, Hsap\DNLZ" viable FBgn0053434 5SrRNA:CR33434 5SrRNA:CR33434 http://flybase.org/reports/FBgn0053434 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33434, 5SrRNA:CR33434" - CR33434 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259624 B0621 - http://flybase.org/reports/FBgn0259624 gene - - - B0621 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible wing FBgn0083270 E(smoDN)2640 Enhancer of smoDN 2640 http://flybase.org/reports/FBgn0083270 gene - - - E(smoDN)2640 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033935 Sin1 SAPK-interacting protein 1 http://flybase.org/reports/FBgn0033935 protein_coding_gene "phosphatidylinositol-4,5-bisphosphate binding ; GO:0005546 | inferred from biological aspect of ancestor with PANTHER:PTN001410677 protein kinase binding ; GO:0019901 | inferred from sequence or structural similarity with UniProtKB:Q9BPZ7" stress-activated protein kinase signaling cascade ; GO:0031098 | inferred from biological aspect of ancestor with PANTHER:PTN001410677 establishment or maintenance of actin cytoskeleton polarity ; GO:0030950 | inferred from biological aspect of ancestor with PANTHER:PTN001410677 regulation of protein phosphorylation ; GO:0001932 | inferred from mutant phenotype TORC2 signaling ; GO:0038203 | inferred from biological aspect of ancestor with PANTHER:PTN001410677 dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype stress granule assembly ; GO:0034063 | inferred from mutant phenotype synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype inferred from genetic interaction with Rheb "plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN001410677 TORC2 complex ; GO:0031932 | inferred from biological aspect of ancestor with PANTHER:PTN001410677 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001410677 TORC2 complex ; GO:0031932 | inferred from sequence or structural similarity with HGNC:18752,PomBase:SPAPYUG7.02c" "Sin1, CG10105, dSin1, sin1" "IPR008828:TORC2 component Sin1/Avo1, IPR032679:Sin1, N-terminal, IPR031313:SAPK-interacting protein 1, Pleckstrin-homology domain, IPR031567:Sin1, middle CRIM domain" CG10105 27-Aug-18 DroID_v2018_08 Drer\mapkap1 Scer\AVO1 Cele\sinh-1 Xtro\mapkap1 Mmus\Mapkap1 Hsap\MAPKAP1 "viable,fertile,neuroanatomy defective,cell autonomous,somatic clone,small body" "class IV dendritic arborizing neuron,cell autonomous,somatic clone,dendrite | cell autonomous | somatic clone,ventral multidendritic neuron vdaB,abdominal anterior ventral multidendritic neuron vdaa,dorsal multidendritic neuron ddaC,embryonic/larval neuromuscular junction,wing" FBgn0051992 gw gawky http://flybase.org/reports/FBgn0051992 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:A1Z7K9 inferred from physical interaction with UniProtKB:A8DY81 inferred from physical interaction with UniProtKB:E1JHY7 inferred from physical interaction with UniProtKB:Q7K126 inferred from physical interaction with UniProtKB:Q8IMX1 inferred from physical interaction with UniProtKB:Q94547 inferred from physical interaction with UniProtKB:Q95RR8 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q32KD4 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P21187 "miRNA mediated inhibition of translation ; GO:0035278 | inferred from electronic annotation with InterPro:IPR033503 gene silencing by miRNA ; GO:0035195 | inferred from mutant phenotype mRNA catabolic process ; GO:0006402 | inferred from mutant phenotype regulation of protein localization ; GO:0032880 | inferred from mutant phenotype embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from direct assay nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ; GO:0000184 | NOT inferred from mutant phenotype locomotor rhythm ; GO:0045475 | inferred from mutant phenotype" cytoplasmic mRNA processing body ; GO:0000932 | inferred from direct assay "CG31992, CG9905, anon-EST:Posey205, CG11484, gw, GW182, dGW182, Gw, GW, gw182, GQ182, Gw182" "IPR019486:Argonaute hook domain, IPR015940:Ubiquitin-associated domain, IPR000504:RNA recognition motif domain, IPR026805:GW182, middle domain, IPR009060:UBA-like, IPR033503:Protein Gawky" CG31992 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-46g23.1, Drer\tnrc6c1, Drer\tnrc6c2, Drer\tnrc6b, Drer\si:dkey-217f16.6" "Scer\UBX6, Scer\UBX7" - "Xtro\tnrc6b, Xtro\tnrc6c" "Mmus\Tnrc6a, Mmus\Tnrc6b, Mmus\Tnrc6c" "Hsap\TNRC6B, Hsap\TNRC6C, Hsap\TNRC6A, Hsap\ADSL" "viable,locomotor rhythm defective,visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC17135 IK 0.665496524 2.6419268 0.618447345 -1.189217022 1.748463007 1.393845439 FBgn0260108 2L3047 - http://flybase.org/reports/FBgn0260108 gene - "terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - 2L3047 - - 27-Aug-18 DroID_v2018_08 - - - - - - "terminal tracheal cell,somatic clone,embryonic/larval tracheal system" FBgn0085302 CG34273 - http://flybase.org/reports/FBgn0085302 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34273 - CG34273 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0003541 St(SD) Stabilizer of Segregation Distorter http://flybase.org/reports/FBgn0003541 - gene - - - "St(SD), St-SD" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260990 yata yata http://flybase.org/reports/FBgn0260990 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719 protein kinase activity ; GO:0004672 | NOT inferred from key residues protein phosphorylation ; GO:0006468 | NOT inferred from key residues - "CG1973, yata, Yata" "IPR000719:Protein kinase domain, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold, IPR011009:Protein kinase-like domain" CG1973 27-Aug-18 DroID_v2018_08 "Drer\scyl1, Drer\scyl3" Scer\CEX1 Cele\W07G4.3 "Xtro\scyl1, Xtro\scyl3" "Mmus\Scyl1, Mmus\Scyl3" "Hsap\SCYL1, Hsap\SCYL3" FBgn0260095 2L3244 - http://flybase.org/reports/FBgn0260095 gene - "terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - 2L3244 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" "terminal tracheal cell,somatic clone,embryonic/larval tracheal system" FBgn0001462 l(1)7Ec lethal (1) 7Ec http://flybase.org/reports/FBgn0001462 - gene - - - l(1)7Ec - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0038002 CG12256 - http://flybase.org/reports/FBgn0038002 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP133, CG12256" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR018114:Serine proteases, trypsin family, histidine active site, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG12256 27-Aug-18 DroID_v2018_08 Drer\st14b - - - Mmus\Ctrc Hsap\CTRC "partially lethal - majority die,some die during pupal stage,viable" FBgn0264372 asRNA:CR43824 - http://flybase.org/reports/FBgn0264372 non_protein_coding_gene - - - CR43824 - CR43824 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0086257 caps::trn - http://flybase.org/reports/FBgn0086257 engineered_fusion_gene - - - caps::trn - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266027 asRNA:TS15 long noncoding RNA: testis-specific 15 http://flybase.org/reports/FBgn0266027 non_protein_coding_gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype - "lncRNA:TS15, CR44792" - CR44792 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264482 lncRNA:CR43890 - http://flybase.org/reports/FBgn0264482 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43890, CR43890" - CR43890 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0016804 l(1)K6 lethal (1) K6 http://flybase.org/reports/FBgn0016804 - gene - - - "l(1)K6, K6" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0053978 CG33978 - http://flybase.org/reports/FBgn0053978 protein_coding_gene "extracellular matrix structural constituent ; GO:0005201 | inferred from electronic annotation with InterPro:IPR011398 calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097 molecular_function ; GO:0003674 | no biological data available" biological_process ; GO:0008150 | no biological data available proteinaceous extracellular matrix ; GO:0005578 | inferred from electronic annotation with InterPro:IPR011398 cellular_component ; GO:0005575 | no biological data available "CG33978, FBgn0053978" "IPR011398:Fibrillin, IPR000742:EGF-like domain, IPR018097:EGF-like calcium-binding, conserved site, IPR000152:EGF-type aspartate/asparagine hydroxylation site, IPR001881:EGF-like calcium-binding domain, IPR013032:EGF-like, conserved site, IPR031866:Domain of unknown function DUF4758" CG33978 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263412 lncRNA:CR43458 - http://flybase.org/reports/FBgn0263412 non_protein_coding_gene - - - "CR43458, lincRNA.913" - CR43458 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0084894 Su(dpp)YE31 Su(dpp)YE31 http://flybase.org/reports/FBgn0084894 gene - - - Su(dpp)YE31 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "embryonic dorsal epidermis,amnioserosa" FBgn0003187 qua quail http://flybase.org/reports/FBgn0003187 "FBgn0000942, FBgn0044556" protein_coding_gene actin binding ; GO:0003779 | inferred from sequence or structural similarity with Gel inferred from sequence or structural similarity with HGNC:12690 inferred from direct assay inferred from mutant phenotype actin binding ; GO:0003779 | inferred from sequence or structural similarity calcium ion binding ; GO:0005509 | inferred from sequence or structural similarity with HGNC:12690 cytoskeleton organization ; GO:0007010 | inferred from electronic annotation with InterPro:IPR003128 actin filament organization ; GO:0007015 | traceable author statement imaginal disc-derived wing hair organization ; GO:0035317 | inferred from mutant phenotype ovarian nurse cell to oocyte transport ; GO:0007300 | inferred from mutant phenotype actin filament ; GO:0005884 | colocalizes_with inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG6433, anon-WO0140519.71, fs(2)A12, qua, Qua" "IPR003128:Villin headpiece, IPR007122:Villin/Gelsolin, IPR007123:Gelsolin-like domain, IPR029006:ADF-H/Gelsolin-like domain" CG6433 27-Aug-18 DroID_v2018_08 "Drer\gsnb, Drer\scinla, Drer\capga, Drer\gsna, Drer\avil, Drer\scinlb, Drer\capgb, Drer\scin, Drer\vil1, Drer\vill" - Cele\gsnl-1 "Xtro\vill, Xtro\capg, Xtro\scin, Xtro\vil1, Xtro\avil, Xtro\gsn" "Mmus\Gsn, Mmus\Scin, Mmus\Vill, Mmus\Avil, Mmus\Capg, Mmus\Vil1" "Hsap\AVIL, Hsap\SCIN, Hsap\CAPG, Hsap\GSN, Hsap\VIL1, Hsap\VILL" " adult stage | female , adult stage && oogenesis stage , embryonic stage | 0-4 hr , pupal stage , spermatogenesis && adult stage " " ovary

, nurse cell

, testis

, oocyte

" adult stage && oogenesis stage " nurse cell

, oocyte

, ring canal

" "female sterile,recessive,viable,fertile,mitotic cell cycle defective,wild-type,heat sensitive" "nurse cell,egg,egg chamber,nurse follicle cell,oocyte,nurse cell ring canal,actin filament & egg chamber,dorsal appendage,female reproductive system,spindle,nurse cell & actin filament,ovary,wing hair" FBgn0000170 bef beta lobes fused http://flybase.org/reports/FBgn0000170 - gene - - - "bef[BG17b], bef" - - 27-Aug-18 DroID_v2018_08 - - - - - - mushroom body beta-lobe FBgn0267002 unc-104 uncoordinated-104 http://flybase.org/reports/FBgn0267002 protein_coding_gene "microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR001752 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001752, InterPro:IPR019821 ATPase activity ; GO:0016887 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 microtubule motor activity ; GO:0003777 | inferred from biological aspect of ancestor with PANTHER:PTN000648413" synaptic vesicle maturation ; GO:0016188 | inferred from mutant phenotype negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype larval locomotory behavior ; GO:0008345 | inferred from mutant phenotype filopodium assembly ; GO:0046847 | inferred from mutant phenotype regulation of synapse assembly ; GO:0051963 | inferred from mutant phenotype positive regulation of insulin secretion ; GO:0032024 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype anterograde axonal transport ; GO:0008089 | inferred from mutant phenotype axo-dendritic transport ; GO:0008088 | inferred from mutant phenotype synaptic vesicle transport ; GO:0048489 | inferred from mutant phenotype regulation of locomotion ; GO:0040012 | inferred from mutant phenotype anterograde synaptic vesicle transport ; GO:0048490 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | inferred from mutant phenotype neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype regulation of dendrite morphogenesis ; GO:0048814 | inferred from mutant phenotype vesicle transport along microtubule ; GO:0047496 | inferred from mutant phenotype axon ; GO:0030424 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from mutant phenotype dendrite ; GO:0030425 | inferred from direct assay kinesin complex ; GO:0005871 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 "unc-104, KIF1A, bris, imac, Unc-104, CG8566, unc104, KIF1A/1B, DUnc-104, DmDUnc104, KIF 1B, DUNC104, DmKlp53D, Klp53D, DmCG8566, Dunc104, Unc104, Imac" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR000253:Forkhead-associated (FHA) domain, IPR001752:Kinesin motor domain, IPR001849:Pleckstrin homology domain, IPR008984:SMAD/FHA domain, IPR011993:PH domain-like, IPR019821:Kinesin motor domain, conserved site, IPR022140:Kinesin-like KIF1-type, IPR022164:Kinesin-like, IPR032405:Kinesin-associated" CG8566 27-Aug-18 DroID_v2018_08 "Drer\kif16ba, Drer\stard9, Drer\ap2b1, Drer\kif1c, Drer\kif1ab, Drer\si:ch73-375g18.1, Drer\kif1b, Drer\kif14, Drer\kif1aa, Drer\kif13ba, Drer\kif16bb, Drer\si:rp71-84d9.2, Drer\kif13bb, Drer\kif13a" "Scer\KIP2, Scer\KIP1, Scer\CIN8" "Cele\unc-104, Cele\klp-6, Cele\klp-4" "Xtro\kif1a, Xtro\kif16b, Xtro\kif1c, Xtro\kif14, Xtro\kif13b, Xtro\kif1b" "Mmus\Kif16b, Mmus\Kif1c, Mmus\Kif14, Mmus\Gm1305, Mmus\Stard9, Mmus\Kif1b, Mmus\Kif13a, Mmus\Kif1a, Mmus\Kif13b" "Hsap\KIF13A, Hsap\KIF1C, Hsap\KIF1B, Hsap\KIF14, Hsap\KIF16B, Hsap\KIF13B, Hsap\KIF1A, Hsap\STARD9" FBgn0040238 Best1 Bestrophin 1 http://flybase.org/reports/FBgn0040238 protein_coding_gene volume-sensitive chloride channel activity ; GO:0072320 | inferred from direct assay intracellular calcium activated chloride channel activity ; GO:0005229 | inferred from mutant phenotype volume-sensitive chloride channel activity ; GO:0072320 | inferred from mutant phenotype chloride channel activity ; GO:0005254 | inferred from direct assay cell volume homeostasis ; GO:0006884 | inferred from direct assay cellular water homeostasis ; GO:0009992 | inferred from direct assay chloride transport ; GO:0006821 | inferred from direct assay cell volume homeostasis ; GO:0006884 | inferred from mutant phenotype integral component of plasma membrane ; GO:0005887 | inferred from direct assay "best, CG6264, dmBest1, dbest1, Dbest, anon-WO0118547.380, Best1, dBest1" "IPR000615:Bestrophin, IPR021134:Bestrophin/UPF0187" CG6264 27-Aug-18 DroID_v2018_08 "Drer\best2, Drer\best1, Drer\best4" - "Cele\best-3, Cele\best-17, Cele\best-6, Cele\sma-10, Cele\C09B9.85, Cele\best-2, Cele\best-12, Cele\best-10, Cele\best-24, Cele\best-14, Cele\best-20, Cele\best-4, Cele\best-21, Cele\best-11, Cele\best-16, Cele\best-8, Cele\best-9, Cele\best-23, Cele\best-5, Cele\best-13, Cele\best-25, Cele\best-19, Cele\best-26, Cele\best-15, Cele\best-18, Cele\best-22, Cele\best-7, Cele\best-1" "Xtro\best1, Xtro\best3, Xtro\best4, Xtro\best2" "Mmus\Best1, Mmus\Best3, Mmus\Best2" "Hsap\BEST4, Hsap\BEST2, Hsap\BEST3, Hsap\BEST1" "viable,fertile" FBgn0083014 snoRNA:Psi18S-996 snoRNA:Psi18S-996 http://flybase.org/reports/FBgn0083014 snoRNA_gene - - - "snoRNA:Psi18S-996, psi18s-996, Psi 18S-996, CR34630, chr3L:245309..245488" - CR34630 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031209 Ir21a Ionotropic receptor 21a http://flybase.org/reports/FBgn0031209 protein_coding_gene ionotropic glutamate receptor activity ; GO:0004970 | inferred from electronic annotation with InterPro:IPR001320 ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus involved in sensory perception ; GO:0050907 | inferred from expression pattern membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001320 integral component of membrane ; GO:0016021 | inferred from sequence model "CT8983, Ir21a, IR21a, CG2657, DmelIR21a, ir21a" IPR001320:Ionotropic glutamate receptor CG2657 27-Aug-18 DroID_v2018_08 "Drer\grid1a, Drer\grid1b, Drer\LOC100537813" - Cele\W02A2.5 - "Mmus\Grik4, Mmus\Grid1" Hsap\GRID1 "partially lethal - majority die,some die during pupal stage,viable,fertile" FBgn0065804 l(2)SH0398 lethal (2) SH0398 http://flybase.org/reports/FBgn0065804 gene - - - "l(2)SH0398, l(2)SH2 0398" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0044495 DTD45.11 DTD45.11 http://flybase.org/reports/FBgn0044495 gene - - - DTD45.11 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0265960 lncRNA:CR44747 - http://flybase.org/reports/FBgn0265960 non_protein_coding_gene - - - "lincRNA.24, CR44747" - CR44747 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0046711 GIIIA GIIIA http://flybase.org/reports/FBgn0046711 gene phospholipase A2 activity ; GO:0004623 | non-traceable author statement - extracellular region ; GO:0005576 | non-traceable author statement "dGIIIA, GIIIA" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000117 arm armadillo http://flybase.org/reports/FBgn0000117 "FBgn0029069, FBgn0040191, FBgn0045040" protein_coding_gene "signal transducer activity ; GO:0004871 | inferred from electronic annotation with InterPro:IPR013284 protein binding ; GO:0005515 | inferred from physical interaction with ssp protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P22265 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P46150 inferred from physical interaction with UniProtKB:Q24564 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P91943 protein binding ; GO:0005515 | inferred from physical interaction with Axn protein phosphatase binding ; GO:0019903 | inferred from biological aspect of ancestor with PANTHER:PTN001153077 kinase binding ; GO:0019900 | inferred from physical interaction with Hipk transcription coactivator activity ; GO:0003713 | inferred from direct assay RNA polymerase II transcription coactivator activity ; GO:0001105 | contributes_to inferred from physical interaction with lgs inferred from physical interaction with pygo protein complex binding ; GO:0032403 | inferred from physical interaction with Exo70, Sec10 transcription factor binding ; GO:0008134 | inferred from direct assay alpha-catenin binding ; GO:0045294 | inferred from biological aspect of ancestor with PANTHER:PTN001153077 cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with Apc2 inferred from physical interaction with Mer protein binding ; GO:0005515 | inferred from physical interaction with Apc2" "wing disc morphogenesis ; GO:0007472 | inferred from mutant phenotype branch fusion, open tracheal system ; GO:0035147 | inferred from mutant phenotype ventral furrow formation ; GO:0007370 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype imaginal disc-derived wing expansion ; GO:0048526 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype delamination ; GO:0060232 | inferred from mutant phenotype cell adhesion ; GO:0007155 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype cytoskeletal anchoring at plasma membrane ; GO:0007016 | inferred from sequence or structural similarity dorsal closure ; GO:0007391 | inferred from genetic interaction with ena protein localization to adherens junction ; GO:0071896 | inferred from mutant phenotype cuticle pattern formation ; GO:0035017 | inferred from mutant phenotype negative regulation of heart induction by canonical Wnt signaling pathway ; GO:0003136 | inferred from mutant phenotype neuroblast development ; GO:0014019 | inferred from mutant phenotype heart formation ; GO:0060914 | inferred from mutant phenotype single organismal cell-cell adhesion ; GO:0016337 | inferred from mutant phenotype heart development ; GO:0007507 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype Wnt signaling pathway ; GO:0016055 | inferred from mutant phenotype cell morphogenesis ; GO:0000902 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay protein localization to plasma membrane ; GO:0072659 | inferred from mutant phenotype zonula adherens assembly ; GO:0045186 | inferred from mutant phenotype nervous system development ; GO:0007399 | inferred from mutant phenotype epithelial cell type specification, open tracheal system ; GO:0035153 | inferred from mutant phenotype long-term memory ; GO:0007616 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype establishment or maintenance of cell polarity ; GO:0007163 | non-traceable author statement somatic stem cell population maintenance ; GO:0035019 | inferred from mutant phenotype compound eye retinal cell programmed cell death ; GO:0046667 | inferred from mutant phenotype branching morphogenesis of an epithelial tube ; GO:0048754 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype chitin-based larval cuticle pattern formation ; GO:0035293 | inferred from mutant phenotype ovarian follicle cell development ; GO:0030707 | traceable author statement cell fate determination ; GO:0001709 | inferred from mutant phenotype photoreceptor cell differentiation ; GO:0046530 | inferred from mutant phenotype epithelium development ; GO:0060429 | inferred from mutant phenotype" apical plasma membrane ; GO:0016324 | inferred from direct assay adherens junction ; GO:0005912 | inferred from direct assay axon ; GO:0030424 | inferred from direct assay catenin complex ; GO:0016342 | inferred from sequence or structural similarity cytoplasm ; GO:0005737 | inferred from direct assay catenin complex ; GO:0016342 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay adherens junction ; GO:0005912 | non-traceable author statement endocytic vesicle ; GO:0030139 | inferred from direct assay apicolateral plasma membrane ; GO:0016327 | traceable author statement spot adherens junction ; GO:0005914 | non-traceable author statement zonula adherens ; GO:0005915 | inferred from direct assay apicolateral plasma membrane ; GO:0016327 | "Arm, arm, beta-cat, CG11579, t12687 ALR Dm, ARM, EG:86E4.6, l(1)G0410, l(1)G0192, l(1)G0234, l(1)arm, l(1)2Bv, beta-cat-arm, beta-Cat, betacat, Dm Arm, beta-catenin/Arm, bgr;-Cat, beta-catenin" "IPR000225:Armadillo, IPR011989:Armadillo-like helical, IPR013284:Beta-catenin, IPR016024:Armadillo-type fold" CG11579 27-Aug-18 DroID_v2018_08 "Drer\ctnnd2a, Drer\ctnnd2b, Drer\armc3, Drer\ctnnb2, Drer\uckl1a, Drer\armc7, Drer\uckl1b, Drer\ctnnb1, Drer\arvcfb, Drer\si:ch211-243j20.2, Drer\jupb, Drer\pkp4, Drer\armc4, Drer\uprt, Drer\jupa" "Scer\FUR1, Scer\VAC8, Scer\URK1" "Cele\wrm-1, Cele\jac-1, Cele\bar-1, Cele\hmp-2" "Xtro\uprt, Xtro\jup, Xtro\armc3, Xtro\armc4, Xtro\ctnnb1" "Mmus\Ctnnd2, Mmus\Uckl1, Mmus\Armc3, Mmus\Armc4, Mmus\Armc7, Mmus\Ctnnb1, Mmus\Uprt, Mmus\Jup, Mmus\Arvcf, Mmus\Pkp4" "Hsap\ARMC3, Hsap\ARVCF, Hsap\ARMC7, Hsap\RAC1, Hsap\UPRT, Hsap\PKP4, Hsap\CTNND2, Hsap\JUP, Hsap\UCKL1, Hsap\CTNNB1" " larval stage , embryonic stage , oogenesis stage && adult stage | female , embryonic stage | stage >12 , embryonic stage | stage 13-14 , embryonic stage | stage 9 , embryonic stage | stage 13-16 , embryonic stage | late , embryonic stage | stage 13 , larval stage | third instar , embryonic stage | stage 17 , embryonic stage | embryonic cycle 14 , embryonic stage | late && larval stage , adult stage " " embryonic/larval salivary gland

, embryonic central nervous system

, follicle cell

, tracheal system

, peripheral nervous system

, gonad | restricted

, eye-antennal disc

, ventral midline

, proctodeum

, sense organ

, midline glial cell

, embryonic/larval foregut

, imaginal disc

, optic lobe

, labral segment

, larval anus

, ventral nerve cord

, gonad | restricted & anterior

, motor neuron &&of intersegmental nerve

, stomodeum

, mesoderm

, embryonic/larval hindgut

, antennal segment

, supraesophageal ganglion

, Malpighian tubule

, tracheal pit

, oocyte

, longitudinal connective

, neuron

, proventriculus

, embryonic/larval digestive system

, ventral nerve cord commissure

, larval brain

, embryonic/larval posterior spiracle

, embryonic peripheral nervous system

, motor neuron &&of segmental nerve

, larval muscle system

, nurse cell

, posterior embryonic/larval midgut

, head

" "viable,fertile,visible,partially lethal - majority die,lethal,lethal - all die before end of embryonic stage,segment polarity phenotype,heat sensitive,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage,recessive,male,female,germline clone,planar polarity defective,cell non-autonomous,somatic clone,cell autonomous,cell polarity defective,cell migration defective,cell shape defective,wild-type,increased cell death,size defective,mitotic cell cycle defective,neuroanatomy defective,memory defective,RU486 conditional,hyperplasia" "wing margin,wing,alula,abdominal sternite 2,abdominal sternite 3,abdominal sternite 4,abdominal sternite 5,abdominal sternite 6,dorsal row,ventral row,tarsal segment,interommatidial bristle,ectopic,somatic clone,abdominal 1 ventral denticle belt,abdominal 2 ventral denticle belt,abdominal 3 ventral denticle belt,abdominal 4 ventral denticle belt,abdominal 5 ventral denticle belt,abdominal 6 ventral denticle belt,abdominal 7 ventral denticle belt,embryonic head,dorsal closure embryo,embryo,segment,tracheal branch primordium,embryonic/larval dorsal trunk,embryonic/larval lateral trunk,RP2 motor neuron,presumptive embryonic/larval central nervous system,longitudinal connective,commissure,embryonic epidermis,embryonic/first instar larval cuticle,follicle stem cell,embryonic/larval tracheal system,abdominal ventral denticle belt,denticle,dorsal,follicle cell,imaginal disc,gonad,oocyte,ovariole,germline clone,egg,nurse cell & nucleus | germ-line clone,egg chamber,nurse cell,nurse cell ring canal,ventral,ovary,embryonic gnathal segment,embryonic segment,cell autonomous,cardial valve,precursor,embryonic dorsal epidermis,embryonic ventral epidermis,embryonic optic lobe primordium,midgut constriction 2,tracheal metamere,embryonic/larval ganglionic branch,embryonic/larval dorsal branch,embryonic/larval dorsal vessel,denticle belt,stomodeal invagination,pleurum,adult cuticle & abdomen | somatic clone,ommatidium,eye,embryonic Malpighian tubule,maternal effect,contractile ring | somatic clone,midbody | somatic clone,female germline stem cell,germline cell,epithelial cell,cytoskeleton | somatic clone,embryonic/larval dorsal branch 10,spiracular branch 10,MP1 neuron,pCC neuron,dMP2 neuron,vMP2 neuron,embryonic ventral nervous system,nurse cell & nucleus,cytoskeleton,actin filament,nurse cell & actin filament,oocyte & actin filament,border follicle cell,dorsal trunk primordium,posterior spiracle primordium,embryonic leading edge cell,syncytial blastoderm embryo,nucleus | embryonic stage 4 | germline clone,spot adherens junction,actin cytoskeleton | embryonic stage | maternal effect,zonula adherens,embryonic/larval cuticle,adherens junction,ventral furrow,embryonic neuroblast,eye photoreceptor cell,spindle | cleavage stage | maternal effect,cell non-autonomous,pigment cell,dorsal margin photoreceptor,retina,heart primordium,adherens junction | germline clone,salivary gland,dorsal mesothoracic disc & peripodial epithelium | somatic clone | cell autonomousë±Tub84B.PL,wing hinge primordium,embryonic/first instar larval cuticle & denticleda.G32,wing margin bristle,wing vein,wing sensillum,crossvein,wing disc,lymph gland derived hemocyte | third instar larval stage,macrochaeta,embryonic/first instar larval cuticle & denticle | ectopicda.G32,morphogenetic furrow,antennal disc,T1 beard,wing hinge,anterior compartment,sensory mother cell & dorsal mesothoracic disc | ectopicsd-SG29.1,embryonic/first instar larval cuticle & denticle beltda.G32,embryonic/larval visceral branch,tracheal fusion cell,supernumerary,terminal tracheal cell,direct flight muscle,denticle row 1,interfollicle cell,heat sensitive,midgut constriction 1,abdominal ventral acute muscle 1 founder cell,abdominal ventral acute muscle 2 founder cell,abdominal ventral acute muscle 3 founder cell,dorsal hair,dorsal denticle,dorsal thick hair,dorsal fine hair,pleural membrane,abdominal sternite bristle,sternite,wing hair,testis,dorsal cluster neuron | adult stage,medulla | adult stage,eye disc,posterior,extended germ band embryo,mesothoracic tergum,adult heart,male genitalia,epithelium,female germline cyst,photoreceptor cell,genital disc,nucleus,embryonic/larval salivary gland,wing & macrochaetaC-765,wing & macrochaeta | ectopicC-765" FBgn0050099 CG30099 - http://flybase.org/reports/FBgn0050099 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG7750, CG30099" - CG30099 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0032477 CG5287 - http://flybase.org/reports/FBgn0032477 protein_coding_gene phospho-N-acetylmuramoyl-pentapeptide-transferase activity ; GO:0008963 | inferred from electronic annotation with InterPro:IPR000715 UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity ; GO:0003975 | inferred from biological aspect of ancestor with PANTHER:PTN000060284 dolichyl diphosphate biosynthetic process ; GO:0006489 | inferred from biological aspect of ancestor with PANTHER:PTN000060284 protein N-linked glycosylation ; GO:0006487 | inferred from biological aspect of ancestor with PANTHER:PTN000060284 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000060284 endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN000060284 "CG5287, dAlg7" "IPR033895:UDP-GlcNAc-dolichyl-phosphate GlcNAc phosphotransferase, IPR000715:Glycosyl transferase, family 4" CG5287 27-Aug-18 DroID_v2018_08 Drer\dpagt1 Scer\ALG7 "Cele\D1005.2, Cele\algn-7" Xtro\dpagt1 Mmus\Dpagt1 Hsap\DPAGT1 FBgn0015405 l(1)11Fc lethal (1) 11Fc http://flybase.org/reports/FBgn0015405 - gene - - - l(1)11Fc - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,semidominant,cold sensitive" FBgn0038058 CG5608 - http://flybase.org/reports/FBgn0038058 protein_coding_gene - regulation of lipid kinase activity ; GO:0043550 | inferred from electronic annotation with InterPro:IPR026825 lateral inhibition ; GO:0046331 | inferred from mutant phenotype PAS complex ; GO:0070772 | inferred from electronic annotation with InterPro:IPR026825 "CG5608, Vac14" "IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold, IPR032878:Vacuole morphology and inheritance protein 14, Fab1-binding region, IPR026825:Vacuole morphology and inheritance protein 14, IPR021841:Vacuolar protein 14 C-terminal Fig4-binding domain" CG5608 27-Aug-18 DroID_v2018_08 Drer\vac14 Scer\VAC14 Cele\vacl-14 Xtro\vac14 Mmus\Vac14 Hsap\VAC14 "viable,fertile,visible" "chaeta,supernumerary,wing" DRSC15841 K 0.163739503 0.097698181 0.201557391 0.226853992 1.873373894 -0.169285038 FBgn0043069 MESK4 Misexpression suppressor of KSR 4 http://flybase.org/reports/FBgn0043069 protein_coding_gene molecular_function ; GO:0003674 | no biological data available positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with ksr inferred from genetic interaction with Ras85D cellular_component ; GO:0005575 | no biological data available "CG31447, BcDNA:LD15753, MESK4" "IPR032675:Leucine-rich repeat domain, L domain-like" CG31447 27-Aug-18 DroID_v2018_08 "Drer\LOC100331330, Drer\c13h10orf11" - Cele\T19D7.6 Xtro\c10orf11 Mmus\1700112E06Rik Hsap\C10orf11 viable FBgn0053283 CR33283 - http://flybase.org/reports/FBgn0053283 pseudogene_attribute - - - "CG33283, CR33283" - CR33283 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0029903 pod1 pod1 http://flybase.org/reports/FBgn0029903 protein_coding_gene "microtubule binding ; GO:0008017 | inferred from direct assay actin filament binding ; GO:0051015 | inferred from direct assay protein binding, bridging ; GO:0030674 | inferred from direct assay actin binding ; GO:0003779 | inferred from sequence or structural similarity" AMPA glutamate receptor clustering ; GO:0097113 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype actin cytoskeleton reorganization ; GO:0031532 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from electronic annotation with InterPro:IPR027331 actin filament ; GO:0005884 | colocalizes_with inferred from direct assay neuromuscular junction ; GO:0031594 | inferred from direct assay cytoplasmic microtubule ; GO:0005881 | colocalizes_with inferred from direct assay growth cone ; GO:0030426 | inferred from direct assay "CG4532, Dpod1, BEST:LD37601, BcDNA:LD08951, pod1, dmPod, coronin, POD-1, Pod1, pod-1" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain, IPR015505:Coronin, IPR001680:WD40 repeat, IPR019775:WD40 repeat, conserved site, IPR027331:Coronin 7, IPR011042:Six-bladed beta-propeller, TolB-like, IPR015048:Domain of unknown function DUF1899, IPR024977:Anaphase-promoting complex subunit 4, WD40 domain" CG4532 27-Aug-18 DroID_v2018_08 "Drer\coro7, Drer\LOC100537938" Scer\CRN1 Cele\pod-1 Xtro\coro7 Mmus\Coro7 "Hsap\CORO7-PAM16, Hsap\CORO7" "viable,fertile,cell shape defective" "intersegmental nerve,segmental nerve,ventral nerve cord,longitudinal connective,commissure" FBgn0032075 Tsp29Fb Tetraspanin 29Fb http://flybase.org/reports/FBgn0032075 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence model integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 "CG9496, Dm.Tsp29Fb, anon-EST:ParkEST130, Tsp29Fb" "IPR018499:Tetraspanin/Peripherin, IPR000048:IQ motif, EF-hand binding site, IPR000301:Tetraspanin, IPR008952:Tetraspanin, EC2 domain" CG9496 27-Aug-18 DroID_v2018_08 "Drer\tspan18a, Drer\upk1a, Drer\cd63, Drer\tspan9b, Drer\tspan9a, Drer\tspan7, Drer\tspan35, Drer\tspan18b, Drer\tspan34, Drer\tspan4b, Drer\tspan4a, Drer\tspan7b, Drer\zgc:64051, Drer\tspan37" - "Cele\tsp-8, Cele\tsp-11, Cele\tsp-13, Cele\tsp-6, Cele\tsp-19, Cele\tsp-5, Cele\tsp-7, Cele\tsp-10, Cele\tsp-4" "Xtro\cd63, Xtro\tspan6" "Mmus\Tspan9, Mmus\Tspan7, Mmus\Upk1a, Mmus\Tspan8, Mmus\Tspan18, Mmus\Tspan1, Mmus\Cd53, Mmus\Cd63, Mmus\Upk1b, Mmus\Tspan4, Mmus\Tspan6" "Hsap\CD63, Hsap\TSPAN8, Hsap\TSPAN6, Hsap\TSPAN18, Hsap\TSPAN4, Hsap\CD53, Hsap\TSPAN1, Hsap\TSPAN9, Hsap\TSPAN16, Hsap\UPK1A, Hsap\UPK1B, Hsap\TSPAN7" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0002137 l(2)K234 lethal (2) K234 http://flybase.org/reports/FBgn0002137 - gene - - - l(2)K234 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0033872 CG6329 - http://flybase.org/reports/FBgn0033872 protein_coding_gene - - - CG6329 - CG6329 27-Aug-18 DroID_v2018_08 - - "Cele\K11H12.6, Cele\F35C5.11, Cele\C15H9.9, Cele\K11H12.7" - - - viable FBgn0036110 Cpr67Fb Cuticular protein 67Fb http://flybase.org/reports/FBgn0036110 protein_coding_gene structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 chitin-based cuticle development ; GO:0040003 | inferred from sequence model multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr67Fb, CG18348, DmelCpr67Fb" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG18348 27-Aug-18 DroID_v2018_08 Drer\LOC100003040 - "Cele\sdz-30, Cele\math-34, Cele\F44F1.4" - "Mmus\H2-K1, Mmus\2410137M14Rik" - viable FBgn0001549 l(1)16Fc lethal (1) 16Fc http://flybase.org/reports/FBgn0001549 - gene - - - "ME-III, l(1)16Fc" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,maternal effect,uncoordinated,somatic clone,neurophysiology defective,recessive,behavior defective,lethal - all die before end of larval stage,dominant,non-rescuable maternal effect,some die during larval stage" "wing,leg" FBgn0052568 CG32568 - http://flybase.org/reports/FBgn0052568 protein_coding_gene protein phosphatase regulator activity ; GO:0019888 | inferred from electronic annotation with InterPro:IPR002554 signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR002554 protein phosphatase type 2A complex ; GO:0000159 | inferred from electronic annotation with InterPro:IPR002554 "CG4724, CG32568" "IPR002554:Protein phosphatase 2A, regulatory B subunit, B56, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold" CG32568 27-Aug-18 DroID_v2018_08 "Drer\ppp2r5ca, Drer\ppp2r5a, Drer\ppp2r5ea, Drer\ppp2r5eb, Drer\ppp2r5b, Drer\ppp2r5d" Scer\RTS1 "Cele\pptr-2, Cele\pptr-1" "Xtro\ppp2r5c, Xtro\ppp2r5b, Xtro\ppp2r5a, Xtro\ppp2r5e" "Mmus\Ppp2r5e, Mmus\Ppp2r5d, Mmus\Ppp2r5a, Mmus\Ppp2r5c, Mmus\Ppp2r5b" "Hsap\PPP2R5E, Hsap\PPP2R5D, Hsap\PPP2R5C, Hsap\PPP2R5B, Hsap\PPP2R5A" viable FBgn0016120 ATPsynD "ATP synthase, subunit D" http://flybase.org/reports/FBgn0016120 - protein_coding_gene "proton-transporting ATP synthase activity, rotational mechanism ; GO:0046933 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000294648 proton-transporting ATP synthase activity, rotational mechanism ; GO:0046933 | contributes_to inferred from sequence or structural similarity with SGD:S000001499" determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype ATP synthesis coupled proton transport ; GO:0015986 | inferred from sequence or structural similarity with SGD:S000001499 response to oxidative stress ; GO:0006979 | inferred from mutant phenotype ATP synthesis coupled proton transport ; GO:0015986 | inferred from biological aspect of ancestor with PANTHER:PTN000294648 ATP metabolic process ; GO:0046034 | inferred from mutant phenotype negative regulation of TOR signaling ; GO:0032007 | inferred from mutant phenotype negative regulation of ERK1 and ERK2 cascade ; GO:0070373 | inferred from mutant phenotype proton transport ; GO:0015992 | inferred from sequence or structural similarity with UniProtKB:O75947 regulation of mitochondrial membrane potential ; GO:0051881 | inferred from mutant phenotype "mitochondrial proton-transporting ATP synthase, stator stalk ; GO:0000274 | inferred from biological aspect of ancestor with PANTHER:PTN000294648 lipid particle ; GO:0005811 | inferred from direct assay mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) ; GO:0000276 | inferred from sequence or structural similarity with UniProtKB:O75947 mitochondrion ; GO:0005739 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay" "CG6030, ATPsyn-delta, ATPsyn-D, ATPsyn-d, ATPQ, ATPsynD, ATP syn-d" "IPR008689:ATP synthase, F0 complex, subunit D, mitochondrial" CG6030 27-Aug-18 DroID_v2018_08 Drer\atp5h Scer\ATP7 Cele\atp-5 Xtro\atp5h Mmus\Atp5h Hsap\ATP5H "lethal,visible,recessive,somatic clone" "eye,somatic clone,eye disc" FBgn0005224 l(3)ET26 lethal Elaine Tasaka 26 http://flybase.org/reports/FBgn0005224 - gene - - - l(3)ET26 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,cold sensitive" FBgn0037583 CG9684 - http://flybase.org/reports/FBgn0037583 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from sequence model with Pfam:PF01753 "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013" precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay CG9684 "IPR002999:Tudor domain, IPR002893:Zinc finger, MYND-type" CG9684 27-Aug-18 DroID_v2018_08 "Drer\smyd1b, Drer\smyd2b, Drer\smyd3, Drer\smyd1a, Drer\smyd2a" - "Cele\set-30, Cele\set-10, Cele\set-18" Xtro\smyd1 "Mmus\Smyd3, Mmus\Smyd2, Mmus\Smyd1" "Hsap\SMYD3, Hsap\SMYD1, Hsap\SMYD2" "viable,fertile" FBgn0040531 CG11741 - http://flybase.org/reports/FBgn0040531 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG11741 - CG11741 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001693 l(1)ESHS14 lethal (1) ESHS14 http://flybase.org/reports/FBgn0001693 - gene - - - "2/16B/1, l(1)ESHS14" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0005715 l(1)TK119 lethal (1) TK119 http://flybase.org/reports/FBgn0005715 - gene - - - "l119, l(1)TK119" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0010730 l(3)00836 lethal (3) 00836 http://flybase.org/reports/FBgn0010730 - gene - - - l(3)00836 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0016755 Toki Toki http://flybase.org/reports/FBgn0016755 - gene - - - Toki - - 27-Aug-18 DroID_v2018_08 - - - - - - "behavior defective,semidominant" FBgn0004575 Syn Synapsin http://flybase.org/reports/FBgn0004575 - protein_coding_gene - neurotransmitter secretion ; GO:0007269 | inferred from electronic annotation with InterPro:IPR001359 male courtship behavior ; GO:0008049 | inferred from mutant phenotype associative learning ; GO:0008306 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype terminal button organization ; GO:0072553 | inferred from mutant phenotype memory ; GO:0007613 | inferred from mutant phenotype synaptic vesicle exocytosis ; GO:0016079 | inferred from sequence or structural similarity response to heat ; GO:0009408 | inferred from mutant phenotype synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype optomotor response ; GO:0071632 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype synaptic vesicle ; GO:0008021 | inferred from electronic annotation with InterPro:IPR001359 terminal bouton ; GO:0043195 | inferred from direct assay "syn, CG3985, SYN2, SYN1, Dsyn-1, Syn, SYN" "IPR001359:Synapsin, IPR016185:Pre-ATP-grasp domain, IPR020897:Synapsin, pre-ATP-grasp domain, IPR020898:Synapsin, ATP-binding domain" CG3985 27-Aug-18 DroID_v2018_08 "Drer\syn3, Drer\syn2a, Drer\syn2b, Drer\syn1" - Cele\snn-1 "Xtro\syn2, Xtro\syn3" "Mmus\Syn2, Mmus\Syn3, Mmus\Syn1" "Hsap\SYN2, Hsap\SYN3, Hsap\SYN1" "viable,fertile,learning defective,short lived,locomotor behavior defective,optomotor response defective,jump response defective,chemical resistant,memory defective,courtship behavior defective,male" FBgn0002913 mwi misheld wings http://flybase.org/reports/FBgn0002913 - gene - - - mwi - - 27-Aug-18 DroID_v2018_08 - - - - - - "male fertile,viable,good,male,female,reduced,female fertile,visible,recessive" "wing,eye" FBgn0034706 CG11275 - http://flybase.org/reports/FBgn0034706 protein_coding_gene ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 regulation of proteolysis ; GO:0030162 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 SCF ubiquitin ligase complex ; GO:0019005 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000698511 "i188, CG11275" "IPR000210:BTB/POZ domain, IPR011333:SKP1/BTB/POZ domain" CG11275 27-Aug-18 DroID_v2018_08 "Drer\kbtbd4, Drer\klhl11, Drer\spopla, Drer\spop, Drer\spoplb" Scer\YIL001W "Cele\hpo-9, Cele\bath-40, Cele\bath-43, Cele\bath-42" - "Mmus\Kbtbd4, Mmus\Spop, Mmus\Gm4858, Mmus\Tdpoz1, Mmus\Gm10696, Mmus\Tdpoz5, Mmus\Klhl11, Mmus\Tdpoz3, Mmus\Tdpoz4, Mmus\Gm9125, Mmus\Tdpoz2, Mmus\Spopl" "Hsap\KBTBD4, Hsap\SPOPL, Hsap\KLHL11, Hsap\SPOP" DRSC04095 E 0.020832688 0.2044938 -1.748534365 0.048734281 0.331738649 0.094925004 FBgn0029838 CG4666 - http://flybase.org/reports/FBgn0029838 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG4666 IPR029069:HotDog domain CG4666 27-Aug-18 DroID_v2018_08 "Drer\si:ch73-52e5.1, Drer\si:ch73-52e5.2" Scer\YBR096W - Xtro\them6 Mmus\Them6 Hsap\THEM6 viable FBgn0021874 Nle Notchless http://flybase.org/reports/FBgn0021874 FBgn0042663 protein_coding_gene Notch binding ; GO:0005112 | traceable author statement Notch signaling pathway ; GO:0007219 | traceable author statement ribosomal large subunit assembly ; GO:0000027 | inferred from biological aspect of ancestor with PANTHER:PTN000457354 nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000457354 ribosome ; GO:0005840 | inferred from biological aspect of ancestor with PANTHER:PTN000457354 "l(2)k13714, anon-WO0026364, CG2863, Nle" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain, IPR001632:G-protein, beta subunit, IPR001680:WD40 repeat, IPR012972:NLE, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat" CG2863 27-Aug-18 DroID_v2018_08 Drer\nle1 Scer\RSA4 "Cele\H24G06.1, Cele\W07E6.2, Cele\dyci-1" Xtro\nle1 Mmus\Nle1 Hsap\NLE1 "lethal,recessive,viable,male sterile,wild-type,partially lethal - majority die,visible" "microchaeta,trichogen cell,mesothoracic tergum,wing hair,supernumerary" FBgn0024654 l(2)k08139 lethal (2) k08139 http://flybase.org/reports/FBgn0024654 - gene - - - "81/39, l(2)k08139" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" imaginal disc FBgn0027617 CG5808 - http://flybase.org/reports/FBgn0027617 - protein_coding_gene "peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from electronic annotation with InterPro:IPR002130, InterPro:IPR024936 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity" "protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR002130, InterPro:IPR024936 protein peptidyl-prolyl isomerization ; GO:0000413 | inferred from electronic annotation with InterPro:IPR002130 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 neurogenesis ; GO:0022008 | inferred from mutant phenotype" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay "BcDNA:GH01073, UKL, cg5808, CG5808" "IPR000504:RNA recognition motif domain, IPR002130:Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain, IPR024936:Cyclophilin-type peptidyl-prolyl cis-trans isomerase, IPR029000:Cyclophilin-like domain" CG5808 27-Aug-18 DroID_v2018_08 Drer\ppil4 "Scer\CPR5, Scer\CPR2, Scer\CWC27" Cele\sig-7 Xtro\ppil4 "Mmus\Rbm7, Mmus\Ppil4, Mmus\Gm3376, Mmus\Rbmy" "Hsap\RBMY1E, Hsap\SNRNP35, Hsap\PPIL4, Hsap\RBMY1B, Hsap\RBMY1D, Hsap\RBMY1A1" "visible,lethal,neuroanatomy defective,partially lethal - majority die,some die during pupal stage" "adult thorax,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0015959 l(2)35Fg lethal (2) 35Fg http://flybase.org/reports/FBgn0015959 - gene - spermatid differentiation ; GO:0048515 | inferred from mutant phenotype - l(2)35Fg - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,male sterile" FBgn0015925 csul capsuleen http://flybase.org/reports/FBgn0015925 FBgn0028723 protein_coding_gene protein-arginine omega-N symmetric methyltransferase activity ; GO:0035243 | inferred from mutant phenotype histone-arginine N-methyltransferase activity ; GO:0008469 | inferred from biological aspect of ancestor with PANTHER:PTN000077429 protein-arginine N-methyltransferase activity ; GO:0016274 | inferred from mutant phenotype protein methyltransferase activity ; GO:0008276 | inferred from mutant phenotype "peptidyl-arginine methylation ; GO:0018216 | inferred from mutant phenotype pole plasm assembly ; GO:0007315 | inferred from mutant phenotype growth ; GO:0040007 | inferred from mutant phenotype peptidyl-arginine methylation, to symmetrical-dimethyl arginine ; GO:0019918 | inferred from biological aspect of ancestor with PANTHER:PTN000077429 transcription, DNA-templated ; GO:0006351 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from biological aspect of ancestor with PANTHER:PTN000077429 intracellular mRNA localization ; GO:0008298 | inferred from mutant phenotype P granule organization ; GO:0030719 | inferred from mutant phenotype pole plasm protein localization ; GO:0007318 | inferred from mutant phenotype ecdysone receptor-mediated signaling pathway ; GO:0035076 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000077429 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000077429 nucleus ; GO:0005634 | inferred from direct assay "csul, DART5, JBP1, CG3730, dart5, dPRMT5, PRMT5, dprmt5, Dart5, Csul" "IPR007857:Protein arginine N-methyltransferase PRMT5, IPR025799:Protein arginine N-methyltransferase, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG3730 27-Aug-18 DroID_v2018_08 "Drer\prmt5, Drer\carm1" Scer\HSL7 Cele\prmt-5 Xtro\prmt5 Mmus\Prmt5 Hsap\PRMT5 "viable,male sterile,grandchildless,fertile,female sterile,recessive" "pole cell,testis,spermatozoon,spermatid,spermatid cyst,embryonic abdominal segment,maternal effect" FBgn0263766 asRNA:CR43683 - http://flybase.org/reports/FBgn0263766 non_protein_coding_gene - - - CR43683 - CR43683 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040828 CG13306 - http://flybase.org/reports/FBgn0040828 protein_coding_gene - - - CG13306 - CG13306 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0038300 Mau2 Mau2 sister chromatid cohesion factor http://flybase.org/reports/FBgn0038300 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Nipped-B double-stranded DNA binding ; GO:0003690 | inferred from biological aspect of ancestor with PANTHER:PTN000483609 axon guidance ; GO:0007411 | inferred from sequence or structural similarity with UniProtKB:O17581 maintenance of mitotic sister chromatid cohesion ; GO:0034088 | inferred from sequence or structural similarity with HGNC:29140 maintenance of mitotic sister chromatid cohesion ; GO:0034088 | inferred from sequence or structural similarity with UniProtKB:Q9Y6X3 maintenance of mitotic sister chromatid cohesion ; GO:0034088 | inferred from biological aspect of ancestor with PANTHER:PTN000483609 nucleoplasm ; GO:0005654 | inferred from sequence or structural similarity with UniProtKB:Q9Y6X3 SMC loading complex ; GO:0032116 | inferred from biological aspect of ancestor with PANTHER:PTN000483609 nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q9Y6X3 chromatin ; GO:0000785 | inferred from sequence or structural similarity with UniProtKB:Q9Y6X3 SMC loading complex ; GO:0032116 | inferred from sequence or structural similarity with UniProtKB:Q9Y6X3 chromatin ; GO:0000785 | inferred from biological aspect of ancestor with PANTHER:PTN000483609 "Mau-2, FBgn0038300, MAU-2, Mau2, MAU2, CG4203, mau-2" "IPR019440:Chromatid cohesion factor MAU2, IPR011990:Tetratricopeptide-like helical domain" CG4203 27-Aug-18 DroID_v2018_08 Drer\mau2 - Cele\mau-2 Xtro\mau2 Mmus\Mau2 Hsap\MAU2 FBgn0069183 mcl(2)Z0218 mcl(2)Z0218 http://flybase.org/reports/FBgn0069183 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(2)Z0218 - - 27-Aug-18 DroID_v2018_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0016820 l(1)L7 lethal (1) L7 http://flybase.org/reports/FBgn0016820 - gene - - - "l(1)L7, L7" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0266635 asRNA:CR45142 - http://flybase.org/reports/FBgn0266635 non_protein_coding_gene - - - CR45142 - CR45142 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0011190 l(1)296-15 lethal (1) 296-15 http://flybase.org/reports/FBgn0011190 FBgn0010201 gene - - - "296-15, l(1)296-15" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0065925 l(2)SH0147 lethal (2) SH0147 http://flybase.org/reports/FBgn0065925 gene - - - "l(2)SH0147, l(2)SH2 0147" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0036305 CG10984 - http://flybase.org/reports/FBgn0036305 protein_coding_gene actin filament binding ; GO:0051015 | inferred from biological aspect of ancestor with PANTHER:PTN001192625 actin filament bundle assembly ; GO:0051017 | inferred from biological aspect of ancestor with PANTHER:PTN001192625 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001192625 nucleoplasm ; GO:0005654 | inferred from direct assay filamentous actin ; GO:0031941 | colocalizes_with inferred from biological aspect of ancestor with PANTHER:PTN001192625 CG10984 - CG10984 27-Aug-18 DroID_v2018_08 "Drer\espnlb, Drer\espn, Drer\espnla, Drer\ankrd11, Drer\ankrd12" Scer\HOS4 "Cele\K02B12.5, Cele\ipla-2, Cele\ipla-3" Xtro\ankrd12 "Mmus\Espnl, Mmus\Ankrd11, Mmus\Ankrd12, Mmus\Espn" "Hsap\ESPNL, Hsap\ESPN, Hsap\ANKRD11, Hsap\ANKRD12" "viable,fertile,partially lethal - majority die,some die during pupal stage" DRSC09817 I -0.837062389 1.53646434 -0.521230289 0.725690648 0.257855167 0.649275555 FBgn0011949 tRNA:Arg-TCG-3-2 transfer RNA:Arginine-TCG 3-2 http://flybase.org/reports/FBgn0011949 "FBgn0011947, FBgn0052620, FBgn0060081" tRNA_gene CGA codon-amino acid adaptor activity ; GO:0033431 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033431 cytosol ; GO:0005829 | inferred by curator from GO:0033431 "tRNA-Arg, tRNA[arg], AE002593.trna5-ArgTCG, tRNA:R1, tRNA:arg1, tRNA:R:TCG:AE002593-c, CR32620, tRNA:arg12Eb, chrX.trna9-ArgTCG, tRNA-Arg-TCG-3-2, tRNA:Arg-TCG-3-2, tRNA:R:12Eb, CGA" - CR32620 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0014935 anon-92Ea anon-92Ea http://flybase.org/reports/FBgn0014935 - gene - - - anon-92Ea - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051355 CG31355 - http://flybase.org/reports/FBgn0051355 protein_coding_gene - - - CG31355 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004425 LysB Lysozyme B http://flybase.org/reports/FBgn0004425 FBgn0002575 protein_coding_gene lysozyme activity ; GO:0003796 | inferred from electronic annotation with InterPro:IPR000974 lysozyme activity ; GO:0003796 | inferred from sequence or structural similarity - - "LysB, lysB, CG1179, Lys B" "IPR000974:Glycoside hydrolase, family 22, lysozyme, IPR001916:Glycoside hydrolase, family 22, IPR019799:Glycoside hydrolase, family 22, conserved site, IPR023346:Lysozyme-like domain" CG1179 27-Aug-18 DroID_v2018_08 "Drer\LOC100536671, Drer\lyz, Drer\LOC100334363" - - Xtro\MGC89221 "Mmus\Lyz2, Mmus\Lyzl1, Mmus\Lalba, Mmus\Spaca1, Mmus\Spaca7, Mmus\Spaca5, Mmus\Lyzl6, Mmus\Lyz1, Mmus\1700016D06Rik, Mmus\Lyzl4, Mmus\9530003J23Rik, Mmus\Spaca3, Mmus\Spaca4" "Hsap\SPACA5, Hsap\SPACA1, Hsap\LALBA, Hsap\SPACA3, Hsap\SPACA4, Hsap\SPACA7, Hsap\LYZL1, Hsap\LYZL4, Hsap\LYZ, Hsap\LYZL6, Hsap\SPACA5B, Hsap\LYZL2" " adult stage , larval stage && adult stage , larval stage " " adult midgut

, embryonic/larval midgut

" FBgn0002260 l(3)68Fe lethal (3) 68Fe http://flybase.org/reports/FBgn0002260 - gene - - - "rsg22, l(3)rsg22, l(3)68Fe" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0003648 Su(z)7 Suppressor of zeste 7 http://flybase.org/reports/FBgn0003648 - gene - - - Su(z)7 - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,reduced" FBgn0267411 CG45764 - http://flybase.org/reports/FBgn0267411 protein_coding_gene - - - "CG45764, Mst77Y" - CG45764 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032624 CG6304 - http://flybase.org/reports/FBgn0032624 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon-WO0140519.248, CG6304" "IPR009818:Ataxin-2, C-terminal" CG6304 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085831 CR42201 - http://flybase.org/reports/FBgn0085831 pseudogene_attribute - - - CR42201 - CR42201 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260317 GSd225 - http://flybase.org/reports/FBgn0260317 gene - - - GSd225 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0001626 l(1)dn3 lethal (1) discs normal 3 http://flybase.org/reports/FBgn0001626 - gene - - - "l(1)d.norm.-3, l(1)dn3" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0054021 CG34021 - http://flybase.org/reports/FBgn0054021 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BP1044, CG34021" - CG34021 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002330 l(3)87Ab lethal (3) 87Ab http://flybase.org/reports/FBgn0002330 - gene - - - "ck9, l(3)ck9, l(3)87Ab" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage,partially lethal - majority die" FBgn0015889 anon-75Ca anon-75Ca http://flybase.org/reports/FBgn0015889 - gene - - - anon-75Ca - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032086 CG17906 - http://flybase.org/reports/FBgn0032086 protein_coding_gene - - - CG17906 - CG17906 27-Aug-18 DroID_v2018_08 - - "Cele\C46E10.2, Cele\srd-56" - - - viable FBgn0265603 AP-2mu::stnB - http://flybase.org/reports/FBgn0265603 engineered_fusion_gene - - - "AP-2mu::stnB, STNB-AP50, STNB-mu2" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0014351 ms(2)HB54 ms(2)HB54 http://flybase.org/reports/FBgn0014351 - gene - - - ms(2)HB54 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0023063 l(1)2Dj lethal (1) 2Dj http://flybase.org/reports/FBgn0023063 - gene - - - "B3/52.19, 800F24, 800D22, l(1)2Dj" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0028575 pp20 pp20 http://flybase.org/reports/FBgn0028575 gene - - - pp20 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035768 CG14834 - http://flybase.org/reports/FBgn0035768 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CT34650, CG14834" - CG14834 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0065441 l(2)SH1458 lethal (2) SH1458 http://flybase.org/reports/FBgn0065441 gene - - - l(2)SH1458 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0011377 l(3)j5B2 lethal (3) j5B2 http://flybase.org/reports/FBgn0011377 - gene - - - l(3)j5B2 - - 27-Aug-18 DroID_v2018_08 - - - - - - partially lethal - majority die FBgn0043991 Su(rst)D63 Su(rst)D63 http://flybase.org/reports/FBgn0043991 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "D63, Su(rst)D63" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266282 jnj java no jive http://flybase.org/reports/FBgn0266282 protein_coding_gene SUMO transferase activity ; GO:0019789 | contributes_to inferred from sequence or structural similarity with SGD:S000004375 damaged DNA binding ; GO:0003684 | inferred from sequence or structural similarity with SGD:S000004375 double-strand break repair via homologous recombination ; GO:0000724 | inferred from electronic annotation with InterPro:IPR027132 response to caffeine ; GO:0031000 | inferred from mutant phenotype DNA repair ; GO:0006281 | inferred from sequence or structural similarity with SGD:S000004375 cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000004375 germinal vesicle ; GO:0042585 | inferred from direct assay Smc5-Smc6 complex ; GO:0030915 | inferred from sequence or structural similarity with SGD:S000004375 "CG5524, AAF56254, jnj, huc95E, Smc6, huc[95D-E], huc[95E], huc[95DE], Huc-95DE, SMC6, smc6" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR027132:Structural maintenance of chromosomes protein 6, IPR003395:RecF/RecN/SMC, N-terminal" CG5524 27-Aug-18 DroID_v2018_08 "Drer\msrb3, Drer\si:dkey-119f1.1, Drer\smc6, Drer\msrb1b, Drer\msrb2" Scer\SMC6 "Cele\smc-5, Cele\smc-6, Cele\F44E2.6, Cele\C23H4.6" "Xtro\msrb2, Xtro\LOC100496941, Xtro\smc6, Xtro\smc6" "Mmus\Msrb2, Mmus\Msrb3, Mmus\Smc6, Mmus\Msrb1" "Hsap\MSRB2, Hsap\SMC6, Hsap\MSRB3" FBgn0034655 CG10307 - http://flybase.org/reports/FBgn0034655 protein_coding_gene - - - "CT28947, CG10307" "IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like, IPR003591:Leucine-rich repeat, typical subtype" CG10307 27-Aug-18 DroID_v2018_08 "Drer\lrrc47, Drer\si:dkey-1h4.4" - Cele\Y54E10A.6 Xtro\lrrc47 "Mmus\Lrrc2, Mmus\Lrrc39, Mmus\Lrrc10b, Mmus\Lrrd1" "Hsap\LRRC10, Hsap\LRRD1, Hsap\LRRC47, Hsap\LRRC39, Hsap\LRRC10B" viable DRSC04057 I 1.55075864 0.879384006 0.111249523 -0.498188965 0.764813819 -0.414527188 FBgn0267633 lncRNA:CR45971 - http://flybase.org/reports/FBgn0267633 non_protein_coding_gene - - - CR45971 - CR45971 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0066323 val valiet http://flybase.org/reports/FBgn0066323 gene molecular_function ; GO:0003674 | no biological data available learning or memory ; GO:0007611 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available val - - 27-Aug-18 DroID_v2018_08 - - - - - - "memory defective,chemical sensitive,neurophysiology defective" FBgn0011054 l(1)Q7 lethal (1) Q7 http://flybase.org/reports/FBgn0011054 FBgn0010210 gene - - - l(1)Q7 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0031803 ppk14 pickpocket 14 http://flybase.org/reports/FBgn0031803 protein_coding_gene sodium channel activity ; GO:0005272 | inferred from sequence or structural similarity with MGI:MGI:101782 sodium ion transport ; GO:0006814 | inferred from sequence or structural similarity with MGI:MGI:101782 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with MGI:MGI:101782 "PPK14, CG9501, ppk14" "IPR001873:Epithelial sodium channel, IPR020903:Epithelial sodium channel, conserved site" CG9501 27-Aug-18 DroID_v2018_08 "Drer\asic1b, Drer\asic4b, Drer\asic1c, Drer\asic4a, Drer\asic2, Drer\asic1a" - "Cele\delm-1, Cele\egas-1, Cele\egas-4, Cele\mec-4, Cele\unc-105, Cele\acd-4, Cele\egas-3, Cele\egas-2, Cele\del-8, Cele\unc-8, Cele\acd-5, Cele\mec-10, Cele\del-10, Cele\flr-1, Cele\delm-2, Cele\del-7, Cele\del-4, Cele\asic-1, Cele\del-1, Cele\degt-1, Cele\acd-1, Cele\asic-2, Cele\acd-2, Cele\deg-1" "Xtro\asic4, Xtro\scnn1d, Xtro\scnn1g, Xtro\scnn1b, Xtro\scnn1a, Xtro\asic5, Xtro\asic1" "Mmus\Asic2, Mmus\Scnn1b, Mmus\Asic3, Mmus\Asic4, Mmus\Scnn1g, Mmus\Asic1, Mmus\Asic5, Mmus\Scnn1a" "Hsap\ASIC4, Hsap\ASIC3, Hsap\ASIC5, Hsap\SCNN1D, Hsap\SCNN1B, Hsap\SCNN1A, Hsap\ASIC2, Hsap\SCNN1G, Hsap\ASIC1" viable FBgn0015342 anon-84Aa anon-84Aa http://flybase.org/reports/FBgn0015342 - gene - - - anon-84Aa - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259104 dar5 dendritic arbor reduction 5 http://flybase.org/reports/FBgn0259104 gene - positive regulation of dendrite morphogenesis ; GO:0050775 | inferred from mutant phenotype - dar5 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0070003 BG01564 BG01564 http://flybase.org/reports/FBgn0070003 gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - BG01564 - - 27-Aug-18 DroID_v2018_08 - - - - - - "stress response defective,viable,smell perception defective" FBgn0065661 l(2)SH0713 lethal (2) SH0713 http://flybase.org/reports/FBgn0065661 gene - - - "l(2)SH0713, l(2)SH2 0713" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0052091 CG32091 - http://flybase.org/reports/FBgn0052091 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR017871 sterol-transporting ATPase activity ; GO:0034041 | inferred from biological aspect of ancestor with PANTHER:PTN001059382 cholesterol transporter activity ; GO:0017127 | inferred from biological aspect of ancestor with PANTHER:PTN001059382" - integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000443108 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000443108 "CG7346, CG14136, CG32091" "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR013525:ABC-2 type transporter, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR017871:ABC transporter, conserved site" CG32091 27-Aug-18 DroID_v2018_08 "Drer\abcg4a, Drer\abcg4b, Drer\abcg1" "Scer\YOL075C, Scer\ADP1" "Cele\wht-2, Cele\wht-6, Cele\abch-1" - "Mmus\Abcg1, Mmus\Abcg5, Mmus\Abcg4" "Hsap\ABCG1, Hsap\ABCG4, Hsap\ABCG5" "viable,fertile" FBgn0041595 l(2)SK1 lethal (2) SK1 http://flybase.org/reports/FBgn0041595 gene - - - l(2)SK1 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0000704 fltJ flight defective J http://flybase.org/reports/FBgn0000704 - gene - - - fltJ - - 27-Aug-18 DroID_v2018_08 - - - - - - flight defective FBgn0038508 CG5866 - http://flybase.org/reports/FBgn0038508 protein_coding_gene - - - CG5866 - CG5866 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC15900 K -0.038468962 -0.736576263 -0.392729477 -0.0490764 1.512516356 0.905920438 FBgn0259184 CG42288 - http://flybase.org/reports/FBgn0259184 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of membrane ; GO:0016021 | inferred from sequence model "CG13353, CG42288" - CG42288 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0029755 Sas10 Something about silencing 10 http://flybase.org/reports/FBgn0029755 protein_coding_gene - "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000462 | inferred from biological aspect of ancestor with PANTHER:PTN000326128 neurogenesis ; GO:0022008 | inferred from mutant phenotype" small-subunit processome ; GO:0032040 | inferred from biological aspect of ancestor with PANTHER:PTN000326128 nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000326128 "sas-10, dSAS10, CG4202, l(1)G0106, Sas10, sas10" "IPR007146:Sas10/Utp3/C1D, IPR018972:Sas10 C-terminal domain" CG4202 27-Aug-18 DroID_v2018_08 Drer\utp3 Scer\SAS10 Cele\T01B7.5 Xtro\utp3 Mmus\Utp3 Hsap\UTP3 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective,partially lethal - majority die,visible,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum,trichogen cell" FBgn0085330 CG34301 - http://flybase.org/reports/FBgn0085330 protein_coding_gene - - - CG34301 - CG34301 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0061020 l(3)S025266 lethal (3) S025266 http://flybase.org/reports/FBgn0061020 gene - - - "0252/66, l(3)S025266" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0034224 insb insensible http://flybase.org/reports/FBgn0034224 protein_coding_gene molecular_function ; GO:0003674 | no biological data available negative regulation of Notch signaling pathway ; GO:0045746 | inferred from genetic interaction with H nucleus ; GO:0005634 | inferred from direct assay "CG6520, insb" - CG6520 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing,macrochaeta" DRSC24404 K -0.385707856 0.006611337 0.490970354 0.514074723 2.713528397 1.767185721 FBgn0037606 CG8032 - http://flybase.org/reports/FBgn0037606 protein_coding_gene "oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR002937, InterPro:IPR023753" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR002937, InterPro:IPR023753" - CG8032 "IPR002937:Amine oxidase, IPR023753:FAD/NAD(P)-binding domain" CG8032 27-Aug-18 DroID_v2018_08 "Drer\smox, Drer\si:dkey-275b16.2, Drer\zgc:66484, Drer\kdm1a, Drer\paox1" Scer\FMS1 "Cele\amx-1, Cele\hpo-15, Cele\spr-5, Cele\amx-3" "Xtro\paox, Xtro\smox, Xtro\kdm1b, Xtro\kdm1a, Xtro\LOC100145496" "Mmus\Paox, Mmus\Smox, Mmus\Kdm1a" "Hsap\KDM1A, Hsap\SMOX, Hsap\PAOX, Hsap\KDM1B" viable FBgn0051480 tRNA:Thr-CGT-1-1 transfer RNA:Threonine-CGT 1-1 http://flybase.org/reports/FBgn0051480 tRNA_gene ACG codon-amino acid adaptor activity ; GO:0033440 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033440 cytosol ; GO:0005829 | inferred by curator from GO:0033440 "AE002708.trna23-ThrCGT, tRNA[Thr][[4]], tRNA[Thr][[3]], tRNA:T3:93AB, tRNA:thr4:93A, tRNA:T4:93A, tRNA:T:CGT:AE002708-a, CR31480, tRNA[[Thr]], chr3R.trna29-ThrCGT, tRNA-Thr-CGT-1-1, tRNA:Thr-CGT-1-1, tRNA:CR31480, ACG" - CR31480 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085380 CG34351 - http://flybase.org/reports/FBgn0085380 protein_coding_gene - - - "CG34351, CG11928, CG15633, ORE-3" IPR026512:RGS7BP/RGS9BP family CG34351 27-Aug-18 DroID_v2018_08 "Drer\rgs7bpa, Drer\si:ch73-167i17.6, Drer\zgc:109913, Drer\rgs7bpb" - Cele\rsbp-1 "Xtro\rgs7bp, Xtro\rgs9bp" "Mmus\Rgs9bp, Mmus\Rgs7bp" "Hsap\RGS7BP, Hsap\RGS9BP" viable FBgn0030666 CG12708 - http://flybase.org/reports/FBgn0030666 protein_coding_gene - - - CG12708 IPR032057:Protein of unknown function DUF4799 CG12708 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" FBgn0031302 CG14340 - http://flybase.org/reports/FBgn0031302 protein_coding_gene - vesicle-mediated transport ; GO:0016192 | inferred from electronic annotation with InterPro:IPR010989 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR010989 CG14340 "IPR010989:SNARE, IPR026512:RGS7BP/RGS9BP family" CG14340 27-Aug-18 DroID_v2018_08 "Drer\rgs7bpb, Drer\si:ch73-167i17.6, Drer\zgc:109913, Drer\rgs7bpa" - Cele\rsbp-1 Xtro\rgs7bp "Mmus\Rgs7bp, Mmus\Rgs9bp" "Hsap\RGS9BP, Hsap\RGS7BP" FBgn0015957 l(1)6Fd lethal (1) 6Fd http://flybase.org/reports/FBgn0015957 - gene - - - "l, l(1)6Fd" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263236 SP1029 SP1029 http://flybase.org/reports/FBgn0263236 protein_coding_gene metalloaminopeptidase activity ; GO:0070006 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 peptide binding ; GO:0042277 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 peptide catabolic process ; GO:0043171 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 lateral inhibition ; GO:0046331 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 "SP1029, CG11956, ptl, ptls" "IPR001930:Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR014782:Peptidase M1, membrane alanine aminopeptidase, N-terminal, IPR024571:ERAP1-like C-terminal domain, IPR034016:Aminopeptidase N-type" CG11956 27-Aug-18 DroID_v2018_08 "Drer\lnpep, Drer\erap1b, Drer\enpep, Drer\si:ch211-149p5.1, Drer\si:ch211-276a23.5, Drer\npepps, Drer\erap1a, Drer\si:ch211-198g19.1, Drer\anpepb, Drer\erap2, Drer\anpepa, Drer\si:ch211-106j24.1" "Scer\APE2, Scer\TMA108, Scer\AAP1" "Cele\T07F10.1, Cele\R03G8.6, Cele\VB0395L.1, Cele\pam-1, Cele\T12E12.6, Cele\AC3.5, Cele\mnp-1, Cele\T16G12.1, Cele\F49B2.6, Cele\R03G8.4, Cele\Y53F4B.20, Cele\Y42A5A.1, Cele\Y67D8C.9" "Xtro\lvrn, Xtro\enpep, Xtro\lnpep, Xtro\npepps, Xtro\anpep, Xtro\erap1" "Mmus\Anpep, Mmus\Enpep, Mmus\Npepps, Mmus\Erap1, Mmus\Trhde, Mmus\Lvrn, Mmus\Lnpep" "Hsap\ANPEP, Hsap\ENPEP, Hsap\NPEPPS, Hsap\ERAP2, Hsap\LVRN, Hsap\ERAP1, Hsap\LNPEP, Hsap\TRHDE" FBgn0027172 l(2)B1 lethal (2) B1 http://flybase.org/reports/FBgn0027172 - gene - - - l(2)B1 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0002334 l(3)87Bb lethal (3) 87Bb http://flybase.org/reports/FBgn0002334 - gene - - - "ck14, l(3)ck14, l(3)87Bb" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0034936 CG2970 - http://flybase.org/reports/FBgn0034936 protein_coding_gene - - membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001972 "CG2970, SD03319p" "IPR001107:Band 7 domain, IPR001972:Stomatin family, IPR032435:Band 7, C-terminal extension" CG2970 27-Aug-18 DroID_v2018_08 "Drer\zgc:112408, Drer\stom, Drer\stoml2, Drer\stoml3b, Drer\stoml3a" - "Cele\mec-2, Cele\stl-1, Cele\sto-2, Cele\sto-1" Xtro\stoml2 "Mmus\Stom, Mmus\Stoml2, Mmus\Stoml3" "Hsap\STOML3, Hsap\STOM, Hsap\STOML2" "viable,fertile,visible" "trichogen cell,mesothoracic tergum" FBgn0028579 phtf phtf http://flybase.org/reports/FBgn0028579 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence model protein dimerization activity ; GO:0046983 | inferred from sequence model" regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence model nucleus ; GO:0005634 | inferred from sequence model "phtf, CG3268, d-phtf, BcDNA.GH08636, BcDNA:GH08636" "IPR021980:Transcription factor homeodomain, male germ-cell" CG3268 27-Aug-18 DroID_v2018_08 "Drer\zgc:175264, Drer\phtf2" - "Cele\sri-73, Cele\sri-48, Cele\sri-45, Cele\sri-30, Cele\sri-29, Cele\sri-24, Cele\sri-54, Cele\sri-43, Cele\sri-67, Cele\sri-46, Cele\sri-66, Cele\T10D4.14, Cele\sri-42, Cele\sri-31, Cele\sri-53, Cele\sri-70, Cele\sri-77, Cele\sri-60, Cele\sri-74, Cele\sri-65, Cele\sri-51, Cele\sri-50, Cele\sri-33, Cele\sri-28, Cele\sri-69" Xtro\phtf2 "Mmus\Phtf1, Mmus\Phtf2" "Hsap\PHTF1, Hsap\PHTF2" adult stage male germline stem cell

viable FBgn0003950 unc uncoordinated http://flybase.org/reports/FBgn0003950 FBgn0031160 protein_coding_gene - non-motile cilium assembly ; GO:1905515 | inferred from mutant phenotype sensory perception of sound ; GO:0007605 | inferred from mutant phenotype locomotory behavior ; GO:0007626 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype ciliary basal body ; GO:0036064 | inferred from direct assay ciliary transition zone ; GO:0035869 | inferred from direct assay centriole ; GO:0005814 | inferred from direct assay "lLV7, W5, 5, 4, 3, CG1501, l(1)6-3-212, l(1)19Ef, unc, UNC, Unc" IPR006594:LIS1 homology motif CG1501 27-Aug-18 DroID_v2018_08 - - "Cele\F54A3.2, Cele\T08D2.8" - - - "viable,fertile,touch sensitivity defective,recessive,behavior defective,somatic clone,lethal,auditory perception defective,uncoordinated,neurophysiology defective,locomotor behavior defective,touch perception defective" "elongation stage spermatid,spermatid axoneme,elongation stage spermatid & nucleus,olfactory neuron & cilium,scolopidial cilium,spermatocyte & centriole,wing,leg,macrochaeta,adult antennal nerve" FBgn0058457 CR40457 5.8SrRNA:CR40457 http://flybase.org/reports/FBgn0058457 rRNA_gene - - - "CR40457, 5.8SrRNA:CR40457" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265822 lncRNA:CR44611 - http://flybase.org/reports/FBgn0265822 non_protein_coding_gene - - - CR44611 - CR44611 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0083264 E(smoDN)529 Enhancer of smoDN 529 http://flybase.org/reports/FBgn0083264 gene - - - E(smoDN)529 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0043380 EP787 EP787 http://flybase.org/reports/FBgn0043380 gene - - - "EP(2)0787, EP0787, EP787" - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "scutellar bristle,tormogen cell" FBgn0036211 CG5946 - http://flybase.org/reports/FBgn0036211 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN000452136 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001433, InterPro:IPR001709, InterPro:IPR001834, InterPro:IPR017927, InterPro:IPR017938 inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype" endomembrane system ; GO:0012505 | inferred from direct assay CG5946 "IPR001433:Oxidoreductase FAD/NAD(P)-binding, IPR001709:Flavoprotein pyridine nucleotide cytochrome reductase, IPR001834:NADH:cytochrome b5 reductase (CBR), IPR008333:Oxidoreductase, FAD-binding domain, IPR017927:Ferredoxin reductase-type FAD-binding domain, IPR017938:Riboflavin synthase-like beta-barrel" CG5946 27-Aug-18 DroID_v2018_08 "Drer\cyb5r2, Drer\cyb5r1, Drer\cyb5r4, Drer\oxnad1, Drer\cyb5r3" "Scer\AIM33, Scer\PGA3, Scer\MCR1, Scer\CYC2, Scer\CBR1" "Cele\T05H4.4, Cele\hpo-19" "Xtro\cyb5r4, Xtro\cyb5r2, Xtro\cyb5r3, Xtro\oxnad1, Xtro\cyb5r1" "Mmus\Cyb5r2, Mmus\Cyb5rl, Mmus\Cyb5r3, Mmus\Oxnad1, Mmus\Cyb5r4, Mmus\Cyb5r1" "Hsap\CYB5R3, Hsap\CYB5R1, Hsap\CYB5R2, Hsap\CYB5R4, Hsap\CYB5RL, Hsap\OXNAD1" "behavior defective,recessive,viable,visible" "embryonic/larval hemocyte | third instar larval stage,trichogen cell" FBgn0032172 CG5850 - http://flybase.org/reports/FBgn0032172 protein_coding_gene transporter activity ; GO:0005215 | inferred from biological aspect of ancestor with PANTHER:PTN000603211 transport ; GO:0006810 | inferred from biological aspect of ancestor with PANTHER:PTN000603211 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000603211 CG5850 IPR005178:Organic solute transporter subunit alpha/Transmembrane protein 184 CG5850 27-Aug-18 DroID_v2018_08 "Drer\tmem184a, Drer\si:dkey-217f16.5, Drer\tmem184ba, Drer\tmem184c, Drer\tmem184bb" Scer\YKR051W Cele\F40E10.6 "Xtro\tmem184c, Xtro\tmem184b, Xtro\tmem184a" "Mmus\Tmem184a, Mmus\Tmem184c, Mmus\Tmem184b" "Hsap\TMEM184C, Hsap\TMEM184A, Hsap\TMEM184B" "viable,fertile" FBgn0032729 L2HGDH L-2-hydroxyglutarate dehydrogenase http://flybase.org/reports/FBgn0032729 protein_coding_gene "oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR006076, InterPro:IPR023753" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006076, InterPro:IPR023753" lipid particle ; GO:0005811 | inferred from direct assay "L2HGDH, CG10639, dL2HGDH" "IPR006076:FAD dependent oxidoreductase, IPR023753:FAD/NAD(P)-binding domain" CG10639 27-Aug-18 DroID_v2018_08 Drer\l2hgdh - Cele\Y45G12B.3 Xtro\l2hgdh Mmus\L2hgdh Hsap\L2HGDH "viable,fertile" FBgn0265443 lncRNA:CR44343 - http://flybase.org/reports/FBgn0265443 non_protein_coding_gene - - - "CR44343, lincRNA.301" - CR44343 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0020794 oo oculus obscurus http://flybase.org/reports/FBgn0020794 - gene - - - oo - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0022740 HLH54F HLH54F http://flybase.org/reports/FBgn0022740 FBgn0020923 protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with da RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from sequence or structural similarity with MGI:MGI:1202715" visceral muscle development ; GO:0007522 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from sequence or structural similarity with MGI:MGI:1202715 inferred from sequence or structural similarity with MGI:MGI:1333884 "bHLH54F, HLH102C, CG5005, HLH54F, bHLHa9, HLH54F-Dm" "IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG5005 27-Aug-18 DroID_v2018_08 "Drer\tcf24, Drer\hand2, Drer\tal1, Drer\tcf15, Drer\tcf23, Drer\tcf21, Drer\tal2, Drer\figla, Drer\mespab, Drer\mespba, Drer\nhlh2, Drer\msgn1, Drer\scxa, Drer\si:ch211-246m6.4, Drer\ascl1a, Drer\ptf1a, Drer\lyl1, Drer\msc, Drer\ascl1b, Drer\scxb, Drer\mespaa" - "Cele\ngn-1, Cele\hlh-10, Cele\cnd-1" "Xtro\nhlh1, Xtro\scx, Xtro\lyl1, Xtro\hand1, Xtro\tcf15, Xtro\ascl2, Xtro\msc, Xtro\tcf21, Xtro\hand2, Xtro\figla, Xtro\mespb, Xtro\ptf1a, Xtro\msgn1, Xtro\mespa, Xtro\ascl3, Xtro\tal1" "Mmus\Tcf23, Mmus\Tal2, Mmus\Ferd3l, Mmus\Lyl1, Mmus\Hand1, Mmus\Msgn1, Mmus\Tcf15, Mmus\Nhlh1, Mmus\Ascl4, Mmus\Nhlh2, Mmus\Msc, Mmus\Scx, Mmus\Tcf24, Mmus\Mesp2, Mmus\Ascl1, Mmus\Figla, Mmus\Ascl5, Mmus\Ptf1a, Mmus\Ascl3, Mmus\Tal1, Mmus\Tcf21, Mmus\Hand2, Mmus\Mesp1" "Hsap\HAND2, Hsap\TCF24, Hsap\TCF23, Hsap\LYL1, Hsap\TCF15, Hsap\TCF21, Hsap\SCX, Hsap\PTF1A, Hsap\ASCL1, Hsap\NHLH2, Hsap\MESP1, Hsap\ASCL5, Hsap\FIGLA, Hsap\MSGN1, Hsap\NHLH1, Hsap\MESP2, Hsap\MSC, Hsap\TAL2, Hsap\ASCL3, Hsap\TAL1, Hsap\ASCL4, Hsap\HAND1" embryonic stage " somatic mesoderm | restricted

, visceral mesoderm | precursor

, visceral mesoderm

" "partially lethal - majority die,increased cell death,lethal,viable,visible" "longitudinal muscle,longitudinal visceral muscle primordium,longitudinal visceral muscle fiber,midgut muscle,cardioblast,embryonic somatic muscle,mesothoracic tergum" FBgn0051158 Efa6 Exchange factor for Arf 6 http://flybase.org/reports/FBgn0051158 protein_coding_gene ARF guanyl-nucleotide exchange factor activity ; GO:0005086 | inferred from electronic annotation with InterPro:IPR000904 phospholipid binding ; GO:0005543 | inferred from electronic annotation with InterPro:IPR001605 regulation of ARF protein signal transduction ; GO:0032012 | inferred from electronic annotation with InterPro:IPR000904 adult chitin-containing cuticle pigmentation ; GO:0048085 | inferred from mutant phenotype regulation of ARF protein signal transduction ; GO:0032012 | inferred by curator from GO:0005086 adherens junction ; GO:0005912 | colocalizes_with inferred from direct assay "EFA6, CG6941, CG18185, CG31158, Efa6, dPsd, dEfa6" "IPR000904:Sec7 domain, IPR001605:Pleckstrin homology domain, spectrin-type, IPR001849:Pleckstrin homology domain, IPR011993:PH domain-like, IPR023394:Sec7 domain, alpha orthogonal bundle, IPR032675:Leucine-rich repeat domain, L domain-like, IPR011990:Tetratricopeptide-like helical domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR011989:Armadillo-like helical, IPR001478:PDZ domain" CG31158 27-Aug-18 DroID_v2018_08 "Drer\psd3l, Drer\psd2, Drer\LOC101886286, Drer\si:ch211-150i13.1" "Scer\BOI2, Scer\GEA2, Scer\GEA1, Scer\SYT1" Cele\efa-6 "Xtro\psd4, Xtro\psd3" "Mmus\Psd3, Mmus\Psd, Mmus\Psd2, Mmus\Psd4" "Hsap\PSD3, Hsap\PSD2, Hsap\PSD4, Hsap\PSD" "viable,fertile" FBgn0033592 CG13215 - http://flybase.org/reports/FBgn0033592 protein_coding_gene - - - CG13215 - CG13215 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC06337 E -0.22054764 0.872038881 1.702989349 0.66404377 -0.096001721 -0.428687673 FBgn0030805 wus wurst http://flybase.org/reports/FBgn0030805 protein_coding_gene - "liquid clearance, open tracheal system ; GO:0035002 | inferred from mutant phenotype regulation of tube length, open tracheal system ; GO:0035159 | inferred from mutant phenotype endocytosis ; GO:0006897 | inferred from mutant phenotype extracellular matrix organization ; GO:0030198 | inferred from mutant phenotype" early endosome ; GO:0005769 | inferred from direct assay cytoplasmic vesicle ; GO:0031410 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "CG9089, l(1)G0162, wus" "IPR001623:DnaJ domain, IPR007829:TM2 domain" CG9089 27-Aug-18 DroID_v2018_08 "Drer\dnajb1b, Drer\dnajc22, Drer\dnajc18, Drer\dnajb4, Drer\dnajb1a, Drer\dnajb5, Drer\dnajb2, Drer\dnajb9a, Drer\dnajb12a, Drer\dnajb12b, Drer\dnajc9, Drer\dnajb14" "Scer\SIS1, Scer\HLJ1" "Cele\dnj-23, Cele\ZK858.5" "Xtro\dnajc22, Xtro\dnajb12, Xtro\dnajb1, Xtro\dnajb4, Xtro\dnajb2, Xtro\dnajb5, Xtro\dnajc18, Xtro\dnajb13, Xtro\dnajb6, Xtro\dnajb14, Xtro\dnajb9" "Mmus\Dnajb8, Mmus\Dnajb13, Mmus\Dnajc21, Mmus\Dnajb4, Mmus\Dnajc9, Mmus\Dnajb3, Mmus\Dnajb5, Mmus\Dnajb1, Mmus\Dnajb2, Mmus\Dnajc22, Mmus\Dnajb6, Mmus\Dnajc18, Mmus\Dnajb12, Mmus\Dnajb9, Mmus\Dnajb14, Mmus\Dnajb7" "Hsap\DNAJC18, Hsap\DNAJC9, Hsap\DNAJB1, Hsap\DNAJC22, Hsap\DNAJB4, Hsap\DNAJB12, Hsap\DNAJB14, Hsap\DNAJB8, Hsap\DNAJB5, Hsap\DNAJB7, Hsap\DNAJB13, Hsap\DNAJB2, Hsap\DNAJB9, Hsap\DNAJB6" "lethal - all die before end of embryonic stage,some die during embryonic stage,recessive,lethal" "embryonic/larval tracheal system,temperature conditional,presumptive embryonic/larval tracheal system,apical plasma membrane & embryonic tracheal system" FBgn0030717 CG8931 - http://flybase.org/reports/FBgn0030717 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG8931 "IPR018108:Mitochondrial substrate/solute carrier, IPR023395:Mitochondrial carrier domain" CG8931 27-Aug-18 DroID_v2018_08 Drer\slc25a46 - Cele\slc-25A46 "Xtro\slc25a19, Xtro\slc25a46" Mmus\Slc25a46 Hsap\SLC25A46 "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0052351 S-Lap2 Sperm-Leucylaminopeptidase 2 http://flybase.org/reports/FBgn0052351 protein_coding_gene "metalloexopeptidase activity ; GO:0008235 | inferred from electronic annotation with InterPro:IPR011356 manganese ion binding ; GO:0030145 | inferred from electronic annotation with InterPro:IPR011356 aminopeptidase activity ; GO:0004177 | inferred from electronic annotation with InterPro:IPR000819, InterPro:IPR008283, InterPro:IPR011356" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000819, InterPro:IPR008283" cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR011356 "BcDNA:LP03301, anon-WO0140519.85, Lap CG32351, CG32351, S-Lap2, S-LAP 2" "IPR000819:Peptidase M17, leucyl aminopeptidase, C-terminal, IPR008283:Peptidase M17, leucyl aminopeptidase, N-terminal, IPR011356:Peptidase M17, leucine aminopeptidase/peptidase B" CG32351 27-Aug-18 DroID_v2018_08 "Drer\rfwd2, Drer\zgc:152830, Drer\npepl1, Drer\lap3" - "Cele\lap-2, Cele\lap-1" "Xtro\lap3, Xtro\rfwd2" "Mmus\Lap3, Mmus\Rfwd2, Mmus\Npepl1" "Hsap\NPEPL1, Hsap\LAP3" viable FBgn0263400 CG43446 - http://flybase.org/reports/FBgn0263400 protein_coding_gene - - - CG43446 "IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR011011:Zinc finger, FYVE/PHD-type" CG43446 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266623 asRNA:CR45130 - http://flybase.org/reports/FBgn0266623 non_protein_coding_gene - - - CR45130 - CR45130 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0043977 Su(tor)321-16-5 Su(tor)321-16-5 http://flybase.org/reports/FBgn0043977 gene - - - "321-16-5, Su(tor)321-16-5" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051679 Tengl3 Testis EndoG-Like 3 http://flybase.org/reports/FBgn0051679 protein_coding_gene "hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR020821 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR020821 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR020821" apoptotic DNA fragmentation ; GO:0006309 | inferred from biological aspect of ancestor with PANTHER:PTN000359601 - "CG17006, Tengl3, CG31679" "IPR001604:DNA/RNA non-specific endonuclease, IPR020821:Extracellular Endonuclease, subunit A" CG31679 27-Aug-18 DroID_v2018_08 "Drer\endog, Drer\LOC103910196, Drer\LOC100333474" Scer\NUC1 Cele\cps-6 "Xtro\exog, Xtro\endog" "Mmus\Endog, Mmus\Exog" "Hsap\ENDOG, Hsap\EXOG" "viable,fertile" FBgn0284253 LeuRS Leucyl-tRNA synthetase http://flybase.org/reports/FBgn0284253 protein_coding_gene "aminoacyl-tRNA editing activity ; GO:0002161 | inferred from electronic annotation with InterPro:IPR009008 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001412, InterPro:IPR002300, InterPro:IPR004493, InterPro:IPR009080, InterPro:IPR015413 leucine-tRNA ligase activity ; GO:0004823 | inferred from biological aspect of ancestor with PANTHER:PTN000236210 valine-tRNA ligase activity ; GO:0004832 | inferred from biological aspect of ancestor with PANTHER:PTN000236067 leucine-tRNA ligase activity ; GO:0004823 | traceable author statement" leucyl-tRNA aminoacylation ; GO:0006429 | traceable author statement wound healing ; GO:0042060 | inferred from mutant phenotype valyl-tRNA aminoacylation ; GO:0006438 | inferred from biological aspect of ancestor with PANTHER:PTN000236067 leucyl-tRNA aminoacylation ; GO:0006429 | inferred from biological aspect of ancestor with PANTHER:PTN000236210 neurogenesis ; GO:0022008 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR004493 aminoacyl-tRNA synthetase multienzyme complex ; GO:0017101 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay cytoplasm ; GO:0005737 | traceable author statement "CG33123, LeuRS, CG3229, anon-EST:Posey266, l(2)SH0501, l(2)SH2 0501" "IPR001412:Aminoacyl-tRNA synthetase, class I, conserved site, IPR002300:Aminoacyl-tRNA synthetase, class Ia, IPR004493:Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic, IPR009008:Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain, IPR009080:Aminoacyl-tRNA synthetase, class Ia, anticodon-binding, IPR013155:Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold, IPR015413:Methionyl/Leucyl tRNA synthetase" CG33123 27-Aug-18 DroID_v2018_08 "Drer\LOC100535691, Drer\larsb" Scer\CDC60 Cele\lars-1 Xtro\lars Mmus\Lars Hsap\LARS "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0000633 CG17716 faint sausage http://flybase.org/reports/FBgn0000633 FBgn0010603 protein_coding_gene - head involution ; GO:0008258 | inferred from mutant phenotype morphogenesis of an epithelium ; GO:0002009 | traceable author statement cardioblast cell fate determination ; GO:0007510 | inferred from mutant phenotype Malpighian tubule morphogenesis ; GO:0007443 | inferred from mutant phenotype salivary gland morphogenesis ; GO:0007435 | traceable author statement morphogenesis of an epithelium ; GO:0002009 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype foregut morphogenesis ; GO:0007440 | inferred from mutant phenotype maintenance of polarity of embryonic epithelium ; GO:0042250 | traceable author statement salivary gland development ; GO:0007431 | inferred from mutant phenotype - "CT39263, l(2)5488, l(2)05488, CG17716, fas" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold" CG17716 27-Aug-18 DroID_v2018_08 "Drer\alcamb, Drer\alcama, Drer\bcam" - - - - - "viable,fertile,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" "interface glial cell,aCC neuron,pCC neuron,MP1 neuron,dMP2 neuron,vMP2 neuron,Malpighian tubule primordium,Malpighian tubule,presumptive embryonic/larval digestive system,embryonic/larval foregut,embryonic/larval proventriculus,midgut constriction,embryonic head,dorsal closure embryo,embryonic epidermis,embryonic/larval salivary gland,embryonic/larval posterior spiracle,adult salivary gland primordium,cardioblast,embryonic/larval pericardial cell,external sensory organ,trichogen cell,tormogen cell,eo neuron,ventral nerve cord,ventral nerve cord commissure,ventral midline,embryonic/first instar larval cuticle,embryonic/larval esophagus,keyhole structure,embryonic/larval hindgut" FBgn0015789 Rab10 Rab10 http://flybase.org/reports/FBgn0015789 - protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579, InterPro:IPR005225 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity" Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 vesicle-mediated transport ; GO:0016192 | inferred from mutant phenotype protein secretion ; GO:0009306 | inferred from biological aspect of ancestor with PANTHER:PTN000635132 growth of a germarium-derived egg chamber ; GO:0007295 | inferred from mutant phenotype vesicle docking involved in exocytosis ; GO:0006904 | inferred from biological aspect of ancestor with PANTHER:PTN000635132 cellular response to insulin stimulus ; GO:0032869 | inferred from biological aspect of ancestor with PANTHER:PTN000756399 vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 lateral inhibition ; GO:0046331 | inferred from mutant phenotype basal protein localization ; GO:0045175 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from biological aspect of ancestor with PANTHER:PTN000756399 vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 cell trailing edge ; GO:0031254 | inferred from direct assay synapse ; GO:0045202 | inferred from direct assay recycling endosome ; GO:0055037 | inferred from direct assay insulin-responsive compartment ; GO:0032593 | inferred from biological aspect of ancestor with PANTHER:PTN000756399 neuronal cell body ; GO:0043025 | inferred from direct assay basal part of cell ; GO:0045178 | inferred from direct assay "AAF50924, DmRab10, rab10, CG17060, DRab10, DRAB10, Rab-r10, Rab10, O15971" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG17060 27-Aug-18 DroID_v2018_08 "Drer\zgc:162879, Drer\rab44, Drer\LOC100535415, Drer\rab40c, Drer\rab40b, Drer\rab1aa, Drer\rab8b, Drer\rab8a, Drer\rab1ab, Drer\rab12, Drer\rasef, Drer\rab13, Drer\rab35b, Drer\rab15, Drer\zgc:171927, Drer\rab10, Drer\si:dkey-16l2.16" Scer\SEC4 "Cele\K02E10.1, Cele\rab-8, Cele\rab-10, Cele\rab-1, Cele\rab-35" "Xtro\rab44, Xtro\rasef, Xtro\LOC100135070, Xtro\rab13, Xtro\rab8b, Xtro\rab15, Xtro\rab1a, Xtro\rasef, Xtro\rab28, Xtro\rab35, Xtro\rab12, Xtro\rab10, Xtro\rab40b, Xtro\rab8a, Xtro\rab35" "Mmus\Rab40b, Mmus\Rab8a, Mmus\Rab13, Mmus\Rab8b, Mmus\Rab12, Mmus\Rab28, Mmus\Rab44, Mmus\Rab15, Mmus\Rab35, Mmus\Rab40c, Mmus\Rab1b, Mmus\Rasef, Mmus\Rab1a, Mmus\Rab10" "Hsap\RAB35, Hsap\RAB40A, Hsap\RAB15, Hsap\RAB12, Hsap\RAB40C, Hsap\RAB8B, Hsap\RAB40B, Hsap\RASEF, Hsap\RAB40AL, Hsap\RAB1B, Hsap\RAB1A, Hsap\RAB8A, Hsap\RAB13, Hsap\RAB28, Hsap\RAB10" "visible,body color defective,partially lethal - majority die,some die during pupal stage,viable" "chaeta,supernumerary,mesothoracic tergum,egg" FBgn0065843 l(2)SH0321 lethal (2) SH0321 http://flybase.org/reports/FBgn0065843 gene - - - "l(2)SH0321, l(2)SH2 0321" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0040780 Atg10 Autophagy-related 10 http://flybase.org/reports/FBgn0040780 protein_coding_gene Atg12 transferase activity ; GO:0019777 | inferred from sequence or structural similarity with SGD:S000003965 macroautophagy ; GO:0016236 | inferred from sequence or structural similarity with SGD:S000003965 cellular protein modification process ; GO:0006464 | inferred from sequence or structural similarity with SGD:S000003965 cellular_component ; GO:0005575 | no biological data available "CG12821, Atg10, ATG10" IPR007135:Autophagy-related protein 3 CG12821 27-Aug-18 DroID_v2018_08 Drer\atg10 - "Cele\atg-10, Cele\D2085.7, Cele\atg-3" - Mmus\Atg10 Hsap\ATG10 FBgn0027957 l(3)S148011a lethal (3) S148011a http://flybase.org/reports/FBgn0027957 gene - - - "1480/11, l(3)S148011, l(3)S148011a" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0265049 lncRNA:CR44164 - http://flybase.org/reports/FBgn0265049 non_protein_coding_gene - - - CR44164 - CR44164 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000538 eb extra bristles http://flybase.org/reports/FBgn0000538 - gene - - - eb - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive" "macrochaeta & scutum,scutellar bristle" FBgn0262623 CG43147 - http://flybase.org/reports/FBgn0262623 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43147, lincRNA.541" - CG43147 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0050213 CR30213 - http://flybase.org/reports/FBgn0050213 non_protein_coding_gene - - - "CR30139, CR30136, CR30213" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262293 mir-2490 mir-2490 stem loop http://flybase.org/reports/FBgn0262293 miRNA_gene - - - "mir-2490, CR43000, dme-mir-2490" - CR43000 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0040832 CG8012 - http://flybase.org/reports/FBgn0040832 protein_coding_gene - - - "BcDNA:GH26995, CG8012" - CG8012 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0002304 l(3)84Cb lethal (3) 84Cb http://flybase.org/reports/FBgn0002304 - gene - - - l(3)84Cb - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0027962 l(3)S145710a lethal (3) S145710a http://flybase.org/reports/FBgn0027962 gene - - - "1067/10, 0479/06, l(3)S106710a, l(3)S145710, l(3)S145710a" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0050421 Usp15-31 Ubiquitin specific protease 15/31 http://flybase.org/reports/FBgn0050421 protein_coding_gene thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from sequence or structural similarity with HGNC:20060 ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from electronic annotation with InterPro:IPR018200 protein deubiquitination ; GO:0016579 | inferred from sequence or structural similarity with HGNC:20060 cellular_component ; GO:0005575 | no biological data available "CG30421, CG9189, CG3872, Usp15-31, Usp15, Usp31, USP43, Q9W117" "IPR001394:Peptidase C19, ubiquitin carboxyl-terminal hydrolase, IPR018200:Ubiquitin specific protease, conserved site, IPR028889:Ubiquitin specific protease domain" CG30421 27-Aug-18 DroID_v2018_08 "Drer\usp33, Drer\usp43b, Drer\usp32, Drer\usp31, Drer\usp11, Drer\usp43a, Drer\usp4, Drer\usp20, Drer\usp19" Scer\UBP12 - "Xtro\usp15, Xtro\usp4, Xtro\usp32, Xtro\usp19, Xtro\usp31, Xtro\usp20, Xtro\usp33" "Mmus\Usp4, Mmus\Usp19, Mmus\Usp20, Mmus\Usp15, Mmus\Usp31, Mmus\Usp33, Mmus\Usp11, Mmus\Usp43, Mmus\Usp32" "Hsap\USP15, Hsap\USP32, Hsap\USP31, Hsap\USP43, Hsap\USP20, Hsap\USP4, Hsap\USP6, Hsap\USP11, Hsap\USP19" "viable,locomotor behavior defective" FBgn0001196 His2A Histone H2A http://flybase.org/reports/FBgn0001196 - protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR002119, InterPro:IPR007125 protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072" larval somatic muscle development ; GO:0007526 | inferred from mutant phenotype chromosome ; GO:0005694 | inferred from direct assay nucleosome ; GO:0000786 | traceable author statement nucleus ; GO:0005634 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay polytene chromosome band ; GO:0005704 | inferred from direct assay nucleosome ; GO:0000786 | inferred from electronic annotation with InterPro:IPR002119 "H2A, HisC, H2A1, H2a, H2A.1, His2a, DmeH2a, H2[[A]], His2A, histone, his, hist, dH2A, dH2a" "IPR009072:Histone-fold, IPR007125:Histone H2A/H2B/H3, IPR002119:Histone H2A, IPR032458:Histone H2A conserved site, IPR032454:Histone H2A, C-terminal domain" - 27-Aug-18 DroID_v2018_08 - - - - - - " adult stage , egg stage | fertilized egg " " spermatozoon

, spermatid | early

, male pronucleus

, spermatid | late

, female pronucleus

" lethal embryonic/larval somatic muscle FBgn0035795 CG16998 - http://flybase.org/reports/FBgn0035795 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "SP104, CG16998" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site" CG16998 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-78l4.10, Drer\LOC558805, Drer\si:dkey-21e2.13, Drer\si:dkey-78l4.4, Drer\si:ch211-165b19.9" - Cele\try-1 "Xtro\cfd, Xtro\prtn3, Xtro\gzmh, Xtro\gzma" "Mmus\Gzmm, Mmus\Prss57" "Hsap\CMA1, Hsap\PRSS57, Hsap\GZMM" viable FBgn0039733 CG11504 - http://flybase.org/reports/FBgn0039733 protein_coding_gene - - - CG11504 IPR006578:MADF domain CG11504 27-Aug-18 DroID_v2018_08 "Drer\zgc:152938, Drer\LOC100330838, Drer\si:ch211-207i20.3" - "Cele\madf-5, Cele\madf-8, Cele\madf-2, Cele\madf-4, Cele\madf-10, Cele\madf-9, Cele\madf-3" - - - viable FBgn0060637 l(3)S084308b lethal (3) S084308b http://flybase.org/reports/FBgn0060637 gene - - - "0843/08, l(3)S084308b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0266043 lncRNA:CR44808 - http://flybase.org/reports/FBgn0266043 non_protein_coding_gene - - - CR44808 - CR44808 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262027 CR42838 - http://flybase.org/reports/FBgn0262027 pseudogene_attribute - - - CR42838 - CR42838 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002508 l(3)SG69 lethal (3) SG69 http://flybase.org/reports/FBgn0002508 - gene - - - l(3)SG69 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0003393 shl shorter legs http://flybase.org/reports/FBgn0003393 - gene - - - shl - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,male fertile,reduced,viable,male" leg FBgn0039357 CG4743 - http://flybase.org/reports/FBgn0039357 protein_coding_gene S-adenosyl-L-methionine transmembrane transporter activity ; GO:0000095 | inferred from sequence or structural similarity with UniProtKB:Q70HW3 S-adenosyl-L-methionine transmembrane transporter activity ; GO:0000095 | inferred from biological aspect of ancestor with PANTHER:PTN000756630 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR002067 S-adenosyl-L-methionine transport ; GO:0015805 | inferred from sequence or structural similarity with UniProtKB:Q70HW3 mitochondrial transport ; GO:0006839 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with UniProtKB:Q70HW3 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN002377827 CG4743 "IPR002067:Mitochondrial carrier protein, IPR018108:Mitochondrial substrate/solute carrier, IPR023395:Mitochondrial carrier domain" CG4743 27-Aug-18 DroID_v2018_08 Drer\slc25a26 "Scer\PET8, Scer\MME1" "Cele\slc-25A26, Cele\F55G1.5" Xtro\slc25a26 Mmus\Slc25a26 Hsap\SLC25A26 "viable,fertile" DRSC15636 K 0.281880371 -0.23979025 -0.289919907 -0.325801128 -1.988401405 -0.81444552 FBgn0002423 l(3)F19 lethal (3) F19 http://flybase.org/reports/FBgn0002423 - gene - - - "l(3)19, l(3)F19" - - 27-Aug-18 DroID_v2018_08 - - - - - - "cell lethalcell lethal,somatic clone,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0259725 CG42379 - http://flybase.org/reports/FBgn0259725 protein_coding_gene - - - "CG42379, Dromel_CG9865_FBtr0071680_uorf2, CG9865(uORF2)" - CG42379 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034141 CG8311 - http://flybase.org/reports/FBgn0034141 protein_coding_gene dolichol kinase activity ; GO:0004168 | inferred from biological aspect of ancestor with PANTHER:PTN000324722 dolichol kinase activity ; GO:0004168 | inferred from sequence or structural similarity with SGD:S000004615 dolichyl monophosphate biosynthetic process ; GO:0043048 | inferred from biological aspect of ancestor with PANTHER:PTN000324722 protein glycosylation ; GO:0006486 | inferred from biological aspect of ancestor with PANTHER:PTN000324722 integral component of endoplasmic reticulum membrane ; GO:0030176 | inferred from biological aspect of ancestor with PANTHER:PTN000324722 CG8311 IPR032974:Polyprenol kinase family CG8311 27-Aug-18 DroID_v2018_08 Drer\dolk "Scer\SEC59, Scer\DGK1" "Cele\srh-167, Cele\Y56A3A.36" Xtro\dolk Mmus\Dolk Hsap\DOLK viable FBgn0032791 CG18094 - http://flybase.org/reports/FBgn0032791 protein_coding_gene "hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR000086, InterPro:IPR015797" - - "CG10048, CG18094" IPR015797:NUDIX hydrolase domain-like CG18094 27-Aug-18 DroID_v2018_08 Drer\nudt19 - Cele\ndx-7 Xtro\nudt19 Mmus\Nudt19 Hsap\NUDT19 FBgn0012018 tRNA:Tyr-GTA-3-1 transfer RNA:Tyrosine-GTA 3-1 http://flybase.org/reports/FBgn0012018 "FBgn0012014, FBgn0051905" tRNA_gene - - - "Tyr-tRNA, tRNA-Tyr, tRNA:tyr1:28C, tRNA[Tyr][[1gamma]], tRNA:Y, CR31905, tRNA[Tyr], tRNA:TyrGUA, tRNA:Tyr-GTA-3-1, tRNA:Y1:28C, tRNA-Und-NNN-1-1" - CR31905 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004764 l(3)89Da lethal (3) 89Da http://flybase.org/reports/FBgn0004764 - gene - - - l(3)89Da - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0266011 lncRNA:CR44784 - http://flybase.org/reports/FBgn0266011 non_protein_coding_gene - - - CR44784 - CR44784 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0013939 E(sina)4 Enhancer of seven in absentia 4 http://flybase.org/reports/FBgn0013939 - gene - - - E(sina)4 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" "photoreceptor cell R7,secondary pigment cell" FBgn0265373 CG44314 - http://flybase.org/reports/FBgn0265373 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44314 - CG44314 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264078 Flo2 Flotillin 2 http://flybase.org/reports/FBgn0264078 protein_coding_gene structural molecule activity ; GO:0005198 | non-traceable author statement cell adhesion ; GO:0007155 | non-traceable author statement melanotic encapsulation of foreign target ; GO:0035011 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay flotillin complex ; GO:0016600 | non-traceable author statement plasma membrane ; GO:0005886 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "CG32593, FLO2, CG14409, CG11547, FLO[Dm]-2, DmFlo2, reggie-1, Flo-2, Flo2, flo2, Flo, mdcds_54791" "IPR001107:Band 7 domain, IPR027705:Flotillin family, IPR031905:Flotillin, C-terminal domain" CG32593 27-Aug-18 DroID_v2018_08 "Drer\flot1a, Drer\flot2a, Drer\flot1b, Drer\flot2b" - - "Xtro\flot1, Xtro\flot2" "Mmus\Flot2, Mmus\Flot1" "Hsap\FLOT1, Hsap\FLOT2" FBgn0085782 CR41101 - http://flybase.org/reports/FBgn0085782 non_protein_coding_gene - - - CR41101 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0013460 fs(3)302 fs(3)302 http://flybase.org/reports/FBgn0013460 - gene - - - fs(3)302 - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive,female sterile,male sterile" FBgn0020348 anon-46Fa anon-46Fa http://flybase.org/reports/FBgn0020348 - gene - - - "6H8, anon-46Fa" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0069932 CG41119 - http://flybase.org/reports/FBgn0069932 protein_coding_gene - - - CG41119 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0283428 lncRNA:CR46271 - http://flybase.org/reports/FBgn0283428 non_protein_coding_gene - - - CR46271 - CR46271 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060913 l(3)S042805b lethal (3) S042805b http://flybase.org/reports/FBgn0060913 gene - - - "0428/05, l(3)S042805b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0058374 CG40374 - http://flybase.org/reports/FBgn0058374 protein_coding_gene - - - CG40374 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030006 CG17982 - http://flybase.org/reports/FBgn0030006 protein_coding_gene - - - CG17982 - CG17982 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0003156 pt platinum http://flybase.org/reports/FBgn0003156 - gene - - - "l(1)VA70, pa, fs(1)M47, l(1)7Fb, pt" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,female sterile,rescuable maternal effect,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,visible,male sterile,male,poor,body color defective" "egg,macrochaeta" FBgn0263934 esn espinas http://flybase.org/reports/FBgn0263934 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781, InterPro:IPR010442" dendrite self-avoidance ; GO:0070593 | inferred from mutant phenotype - "CG43722, esn, CG12833, CG12835, Dm_2R:11728" "IPR010442:PET domain, IPR001781:Zinc finger, LIM-type, IPR033725:LIM1 prickle, IPR033727:LIM3 prickle, IPR033723:PET prickle, IPR033726:LIM2 prickle" CG43722 27-Aug-18 DroID_v2018_08 "Drer\znf185, Drer\fhl1b, Drer\lmo7a, Drer\fhl2b, Drer\fhl3b, Drer\tes, Drer\limd2, Drer\prickle3, Drer\prickle2b, Drer\limch1a, Drer\prickle1a, Drer\fhl3a, Drer\fhl2a, Drer\limch1b, Drer\lmo7b, Drer\prickle2a, Drer\fhl1a, Drer\prickle1b" "Scer\RGA2, Scer\RGA1, Scer\LRG1" "Cele\tes-1, Cele\lim-9, Cele\prkl-1" "Xtro\fhl2, Xtro\lmo7, Xtro\prickle1, Xtro\lmcd1, Xtro\prickle2, Xtro\fhl3, Xtro\tes, Xtro\scel, Xtro\fhl1, Xtro\limch1, Xtro\fhl5" "Mmus\Lmcd1, Mmus\Fhl2, Mmus\Tes, Mmus\Prickle3, Mmus\Prickle1, Mmus\Limd2, Mmus\Zfp185, Mmus\Lmo7, Mmus\Fhl1, Mmus\Fhl3, Mmus\Prickle2, Mmus\Prickle4, Mmus\Fhl5, Mmus\Fhl4, Mmus\Gm4907" "Hsap\LMCD1, Hsap\PRICKLE4, Hsap\FHL5, Hsap\PRICKLE1, Hsap\FHL3, Hsap\FHL1, Hsap\LIMD2, Hsap\PRICKLE2, Hsap\TES, Hsap\ZNF185, Hsap\LMO7, Hsap\FHL2, Hsap\PRICKLE3" FBgn0002802 ms(1)19Fa male sterile (1) 19Fa http://flybase.org/reports/FBgn0002802 - gene - - - "ms(1)D, ms(1)19Fa" - - 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,recessive" FBgn0025503 l(3)73Ak lethal (3) 73Ak http://flybase.org/reports/FBgn0025503 - gene - - - l(3)73Ak - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0051697 CG31697 - http://flybase.org/reports/FBgn0051697 protein_coding_gene - - - "CG10355, CG31697" - CG31697 27-Aug-18 DroID_v2018_08 "Drer\cept1b, Drer\cept1a, Drer\chpt1, Drer\si:ch211-197l9.4" "Scer\EPT1, Scer\CPT1" - "Xtro\cept1, Xtro\ept1, Xtro\chpt1" "Mmus\Chpt1, Mmus\Selenoi, Mmus\Cept1" "Hsap\SELENOI, Hsap\CEPT1, Hsap\CHPT1" viable FBgn0060665 l(3)S080707a lethal (3) S080707a http://flybase.org/reports/FBgn0060665 gene - - - "0807/07, l(3)S080707a" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal" FBgn0024542 Neos Neosin http://flybase.org/reports/FBgn0024542 FBgn0027902 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011" precatalytic spliceosome ; GO:0071011 | inferred from direct assay "CG8614, BcDNA:HL05936, l(3)L2249, BcDNA.HL05936, Neos" "IPR000504:RNA recognition motif domain, IPR004154:Anticodon-binding" CG8614 27-Aug-18 DroID_v2018_08 "Drer\raly, Drer\ncoa5, Drer\si:ch211-216l23.2, Drer\nup98" Scer\NUP145 "Cele\col-17, Cele\ztf-4" "Xtro\nup98, Xtro\LOC100145527, Xtro\ncoa5" "Mmus\Ncoa5, Mmus\Nup98" "Hsap\NCOA5, Hsap\NUP98, Hsap\RALY" "lethal,recessive,viable" DRSC11235 I 2.321832856 1.378441246 0.627364268 0.071544028 -0.693101126 -1.086718639 FBgn0065209 l(2)SH2263 lethal (2) SH2263 http://flybase.org/reports/FBgn0065209 gene - - - "l(2)SH2263, l(2)SH2 2263" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0016866 l(2)39ADd lethal (2) 39ADd http://flybase.org/reports/FBgn0016866 - gene - - - "H221, l(2)39ADd" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0035057 CG3880 - http://flybase.org/reports/FBgn0035057 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG3880 "IPR011992:EF-hand domain pair, IPR026828:Suppressor APC domain-containing protein 1/2" CG3880 27-Aug-18 DroID_v2018_08 Drer\sapcd2 - Cele\T01B6.1 - "Mmus\Sapcd1, Mmus\Sapcd2" "Hsap\SAPCD2, Hsap\SAPCD1" viable FBgn0082994 snoRNA:Psi28S-1837c snoRNA:Psi28S-1837c http://flybase.org/reports/FBgn0082994 snoRNA_gene - - - "snoRNA:Psi28S-1837c, Psi28S-1837c, psi28S-1837c, CR34638" - CR34638 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0023545 PIG-K Phosphatidylinositol glycan anchor biosynthesis class K http://flybase.org/reports/FBgn0023545 - protein_coding_gene peptidase activity ; GO:0008233 | inferred from electronic annotation with InterPro:IPR001096 GPI-anchor transamidase activity ; GO:0003923 | inferred from sequence or structural similarity with UniProtKB:Q92643 GPI-anchor transamidase activity ; GO:0003923 | inferred from biological aspect of ancestor with PANTHER:PTN000243120 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001096 attachment of GPI anchor to protein ; GO:0016255 | inferred from biological aspect of ancestor with PANTHER:PTN000243120 protein localization to cell surface ; GO:0034394 | inferred from biological aspect of ancestor with PANTHER:PTN000243120 GPI-anchor transamidase complex ; GO:0042765 | inferred from sequence or structural similarity with UniProtKB:Q92643 GPI-anchor transamidase complex ; GO:0042765 | inferred from biological aspect of ancestor with PANTHER:PTN000243120 "EG:133E12.3, cg4406, PIG-K, CG4406" "IPR001096:Peptidase C13, legumain, IPR028361:GPI-anchor transamidase" CG4406 27-Aug-18 DroID_v2018_08 Drer\pigk Scer\GPI8 Cele\hpo-4 Xtro\pigk Mmus\Pigk Hsap\PIGK FBgn0002602 M(2)44C Minute (2) 44C http://flybase.org/reports/FBgn0002602 - gene - - - "M(2)38b, M(2)44C" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0011033 l(3)s2681 lethal (3) s2681 http://flybase.org/reports/FBgn0011033 - gene - - - l(3)s2681 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0051155 Rpb7 Rpb7 http://flybase.org/reports/FBgn0051155 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR003029 protein binding ; GO:0005515 | inferred from physical interaction with Rpb4 DNA-directed RNA polymerase activity ; GO:0003899 | inferred from sequence or structural similarity with HGNC:9194 inferred from sequence or structural similarity with SGD:S000002812 transcription from RNA polymerase II promoter ; GO:0006366 | inferred from sequence or structural similarity with HGNC:9194 inferred from sequence or structural similarity with SGD:S000002812 "DNA-directed RNA polymerase II, core complex ; GO:0005665 | inferred from physical interaction with Rpb4 DNA-directed RNA polymerase II, core complex ; GO:0005665 | inferred from sequence or structural similarity with HGNC:9194 inferred from sequence or structural similarity with SGD:S000002812" "dRpb7, RPB7, CG6572, CG31155, Rpb7" "IPR003029:S1 domain, IPR005576:RNA polymerase Rpb7, N-terminal, IPR012340:Nucleic acid-binding, OB-fold" CG31155 27-Aug-18 DroID_v2018_08 Drer\polr2gl Scer\RPB7 Cele\rpb-7 Xtro\polr2g Mmus\Polr2g Hsap\POLR2G "viable,fertile,lethal" DRSC16068 IEK 2.650413799 3.198140773 -1.997283187 -2.38056349 2.423196075 1.066874048 FBgn0038641 CG7708 - http://flybase.org/reports/FBgn0038641 protein_coding_gene choline transmembrane transporter activity ; GO:0015220 | inferred from sequence or structural similarity with UniProtKB:Q9GZV3 choline binding ; GO:0033265 | inferred from biological aspect of ancestor with PANTHER:PTN001721680 amino acid transmembrane transporter activity ; GO:0015171 | inferred from sequence or structural similarity with Eaat1 choline:sodium symporter activity ; GO:0005307 | inferred from biological aspect of ancestor with PANTHER:PTN001721680 acetylcholine biosynthetic process ; GO:0008292 | inferred from sequence or structural similarity with UniProtKB:Q9GZV3 choline transport ; GO:0015871 | inferred from biological aspect of ancestor with PANTHER:PTN001721680 acetylcholine biosynthetic process ; GO:0008292 | inferred from biological aspect of ancestor with PANTHER:PTN001721680 amino acid transmembrane transport ; GO:0003333 | inferred from sequence or structural similarity with Eaat1 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with UniProtKB:Q9GZV3 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000213391 "CG7708, dSLC5A15" IPR001734:Sodium/solute symporter CG7708 27-Aug-18 DroID_v2018_08 "Drer\LOC799259, Drer\slc5a7a" Scer\DUR3 Cele\cho-1 Xtro\slc5a7 Mmus\Slc5a7 Hsap\SLC5A7 viable FBgn0030003 CG2116 - http://flybase.org/reports/FBgn0030003 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype - CG2116 IPR013087:Zinc finger C2H2-type CG2116 27-Aug-18 DroID_v2018_08 "Drer\znf668, Drer\zgc:162948, Drer\znf142, Drer\im:7147486" Scer\RME1 "Cele\fezf-1, Cele\M03D4.4, Cele\sdz-12, Cele\eor-1, Cele\hinf-1" Xtro\znf668 "Mmus\Zfp574, Mmus\Zfp142, Mmus\Zfp668" "Hsap\ZNF215, Hsap\ZIK1, Hsap\ZNF212, Hsap\ZNF713, Hsap\ZNF75A, Hsap\ZNF746, Hsap\ZNF398, Hsap\ZNF777, Hsap\ZNF574, Hsap\ZNF705E, Hsap\ZNF587B, Hsap\ZNF705B, Hsap\ZNF705D, Hsap\ZNF763, Hsap\ZNF705G, Hsap\ZNF282, Hsap\ZNF668, Hsap\ZNF705A, Hsap\ZNF142, Hsap\ZNF552" "neuroanatomy defective,viable" "dorsal multidendritic neuron ddaC,ventral multidendritic neuron vdaB,abdominal ventral multidendritic neuron v'dap" FBgn0011284 RpS4 Ribosomal protein S4 http://flybase.org/reports/FBgn0011284 FBgn0025296 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR002942 structural constituent of ribosome ; GO:0003735 | inferred from direct assay structural constituent of ribosome ; GO:0003735 | traceable author statement translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR000876 centrosome organization ; GO:0051297 | inferred from mutant phenotype cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 centrosome duplication ; GO:0051298 | inferred from mutant phenotype cytoplasmic translation ; GO:0002181 | traceable author statement cytosolic ribosome ; GO:0022626 | inferred from direct assay ribosome ; GO:0005840 | inferred from direct assay cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement "SX4, rpS4, RPS4, anon-EST:Posey270, CG11276, RpS4, Rp S4" "IPR018199:Ribosomal protein S4e, N-terminal, conserved site, IPR000876:Ribosomal protein S4e, IPR002942:RNA-binding S4 domain, IPR005824:KOW, IPR013843:Ribosomal protein S4e, N-terminal, IPR013845:Ribosomal protein S4e, central region, IPR032277:40S ribosomal protein S4, C-terminal domain" CG11276 27-Aug-18 DroID_v2018_08 Drer\rps4x "Scer\RPS4A, Scer\RPS4B" Cele\rps-4 Xtro\rps4x Mmus\Rps4x "Hsap\RPS4Y2, Hsap\RPS4X, Hsap\RPS4Y1" "lethal - all die before end of pupal stage,some die during pupal stage" DRSC11272 EK -0.82511944 -0.274034651 0.15711297 -3.774973909 1.255007503 3.195982836 FBgn0001493 l(1)10Bg lethal (1) 10Bg http://flybase.org/reports/FBgn0001493 - gene - - - "10Bg, l(1)GLM20, l(1)G20, l(1)10Bg" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage,maternal effect,lethal" "ovariole,germline clone,egg,egg chamber,maternal effect,macrochaeta" FBgn0014930 CG2846 - http://flybase.org/reports/FBgn0014930 - protein_coding_gene riboflavin kinase activity ; GO:0008531 | inferred from sequence or structural similarity with SGD:S000002644 "riboflavin biosynthetic process ; GO:0009231 | inferred from electronic annotation with InterPro:IPR015865, InterPro:IPR023465 FMN biosynthetic process ; GO:0009398 | inferred from sequence or structural similarity with SGD:S000002644" cellular_component ; GO:0005575 | no biological data available "C, anon-84Ea, CG2846" "IPR023465:Riboflavin kinase domain, IPR023468:Riboflavin kinase, IPR015865:Riboflavin kinase domain, bacterial/eukaryotic" CG2846 27-Aug-18 DroID_v2018_08 Drer\rfk Scer\FMN1 Cele\R10H10.6 Xtro\rfk Mmus\Rfk Hsap\RFK DRSC15454 I 1.514014056 0.622911737 0.207042151 0.017693266 0.653123358 -0.238126751 FBgn0034071 CG8405 - http://flybase.org/reports/FBgn0034071 protein_coding_gene - "wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap" - "CG8405, R5_2R:11947059..11948303" IPR019144:Membralin CG8405 27-Aug-18 DroID_v2018_08 Drer\tmem259 - Cele\Y59C2A.2 Xtro\tmem259 Mmus\Tmem259 Hsap\TMEM259 viable FBgn0265675 lncRNA:CR44482 - http://flybase.org/reports/FBgn0265675 non_protein_coding_gene - - - CR44482 - CR44482 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266830 lncRNA:CR45292 - http://flybase.org/reports/FBgn0266830 non_protein_coding_gene - - - CR45292 - CR45292 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002128 l(2)K201 lethal (2) K201 http://flybase.org/reports/FBgn0002128 - gene - - - l(2)K201 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0060469 l(3)S112803 lethal (3) S112803 http://flybase.org/reports/FBgn0060469 gene - - - "1128/03, l(3)S112803" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0261635 CG42718 - http://flybase.org/reports/FBgn0261635 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42718 - CG42718 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0050332 CG30332 - http://flybase.org/reports/FBgn0050332 protein_coding_gene - - - "BcDNA:AT17896, CG30332" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0016636 E(gl)3D Enhancer of glass 3D http://flybase.org/reports/FBgn0016636 - gene - - - E(gl)3D - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" presumptive embryonic/larval central nervous system FBgn0039244 CG11069 - http://flybase.org/reports/FBgn0039244 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439 sterol-transporting ATPase activity ; GO:0034041 | inferred from biological aspect of ancestor with PANTHER:PTN001059382 cholesterol transporter activity ; GO:0017127 | inferred from biological aspect of ancestor with PANTHER:PTN001059382 - integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000443108 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000443108 CG11069 "IPR003439:ABC transporter-like, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG11069 27-Aug-18 DroID_v2018_08 "Drer\abcg8, Drer\abcg4a, Drer\abcg5, Drer\abcg4b, Drer\abcg2b, Drer\abcg2a, Drer\abcg1" "Scer\PDR12, Scer\ADP1, Scer\PDR11, Scer\ARB1, Scer\AUS1, Scer\PDR10, Scer\YOL075C" "Cele\wht-6, Cele\abch-1, Cele\wht-2" "Xtro\abcg5, Xtro\abcg8" "Mmus\Abcg8, Mmus\Abcg5, Mmus\Abcg4, Mmus\Abcg3, Mmus\Abcg1, Mmus\Abcg2" "Hsap\ABCG4, Hsap\ABCG1, Hsap\ABCG8, Hsap\ABCG5" FBgn0267501 18SrRNA:CR45841 18S ribosomal RNA:CR45841 http://flybase.org/reports/FBgn0267501 rRNA_gene - - - "18SrRNA:CR45841, CR45841" - CR45841 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039270 PQBP1 Poly-glutamine tract binding protein 1 http://flybase.org/reports/FBgn0039270 protein_coding_gene - "microvillus organization ; GO:0032528 | inferred from mutant phenotype rhabdomere development ; GO:0042052 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 positive regulation of translation ; GO:0045727 | inferred from direct assay" rough endoplasmic reticulum ; GO:0005791 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay "PQBP1, dPQBP1, CG11820, PQBP-1, dPQBP-1" IPR001202:WW domain CG11820 27-Aug-18 DroID_v2018_08 Drer\pqbp1 - "Cele\pqbp-1.2, Cele\pqbp-1.1" - "Mmus\Pqbp1, Mmus\Leo1" Hsap\PQBP1 "viable,fertile,short lived,semidominant,learning defective" DRSC14393 K -1.180289559 -0.355972979 -0.891118449 0.475330872 3.004068797 0.371146393 FBgn0267561 lncRNA:CR45901 - http://flybase.org/reports/FBgn0267561 non_protein_coding_gene - - - CR45901 - CR45901 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0053733 snmRNA:430g snmRNA:430:CR33733 http://flybase.org/reports/FBgn0053733 non_protein_coding_gene - - - "CR33733, snmRNA:430:CR33733" - CR33733 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060551 l(3)S098202b lethal (3) S098202b http://flybase.org/reports/FBgn0060551 gene - - - "0982/02, l(3)S098202b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0085317 CG34288 - http://flybase.org/reports/FBgn0085317 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34288 - CG34288 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0022305 l(1)L35.1 lethal (1) L35.1 http://flybase.org/reports/FBgn0022305 - gene - - - "L35.1, l(1)L35.1" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0034761 CG4250 - http://flybase.org/reports/FBgn0034761 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CT13934, BcDNA:RH52355, CG4250" IPR006629:LPS-induced tumour necrosis factor alpha factor CG4250 27-Aug-18 DroID_v2018_08 "Drer\litaf, Drer\si:dkeyp-75b4.8, Drer\si:ch211-202h22.8, Drer\cdip1, Drer\si:ch211-202h22.9, Drer\si:ch211-202h22.7, Drer\si:ch211-157c3.4" - "Cele\Y87G2A.19, Cele\B0348.2, Cele\F36G3.3, Cele\Y40H7A.11, Cele\Y87G2A.18, Cele\Y37D8A.6, Cele\Y22D7AL.15, Cele\Y37D8A.26, Cele\F16F9.1, Cele\C08E8.1, Cele\Y37D8A.8, Cele\B0348.1" Xtro\litaf "Mmus\Cdip1, Mmus\Litaf" "Hsap\LITAF, Hsap\CDIP1" viable DRSC04455 K 0.909645007 0.028037528 0.751082044 0.047464076 2.021868905 1.167696855 FBgn0000034 AcpK Accessory gland protein K http://flybase.org/reports/FBgn0000034 - gene - - - AcpK - - 27-Aug-18 DroID_v2018_08 - - - - - - electrophoretic variant FBgn0259307 EP-179 - http://flybase.org/reports/FBgn0259307 gene - - - EP-179 - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,lethal" "wing,chaeta" FBgn0052074 CG32074 - http://flybase.org/reports/FBgn0052074 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32074 - CG32074 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,some die during pupal stage,viable" DRSC22246 E 0.166899979 -0.004013923 1.536377871 0.445635472 -0.428984842 -1.022940209 FBgn0063643 CE3-3 CE3-3 http://flybase.org/reports/FBgn0063643 gene - - - CE3-3 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0014977 l(1)BP l(1)Brand and Perrimon http://flybase.org/reports/FBgn0014977 - gene - - - l(1)BP - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0020336 anon-65Bb anon-65Bb http://flybase.org/reports/FBgn0020336 - gene - - - "y, anon-65Bb" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266834 lncRNA:CR45296 - http://flybase.org/reports/FBgn0266834 non_protein_coding_gene - - - CR45296 - CR45296 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0011573 Cdc37 Cdc37 http://flybase.org/reports/FBgn0011573 FBgn0004640 protein_coding_gene protein kinase binding ; GO:0019901 | inferred from electronic annotation with InterPro:IPR013855 protein tyrosine kinase activator activity ; GO:0030296 | non-traceable author statement heat shock protein binding ; GO:0031072 | inferred from biological aspect of ancestor with PANTHER:PTN000980613 unfolded protein binding ; GO:0051082 | inferred from biological aspect of ancestor with PANTHER:PTN000980613 chaperone binding ; GO:0051087 | inferred from biological aspect of ancestor with PANTHER:PTN000980613 chaperone binding ; GO:0051087 | non-traceable author statement intracellular signal transduction ; GO:0035556 | non-traceable author statement protein folding ; GO:0006457 | inferred from biological aspect of ancestor with PANTHER:PTN000980613 positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with Ras85D positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from genetic interaction with Ras85D protein stabilization ; GO:0050821 | inferred from biological aspect of ancestor with PANTHER:PTN000980613 neurogenesis ; GO:0022008 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:Q16543 "cdc37, DROCPDR, CPDR-2, CPDR-1, E(sev)3B, CG12019, Cdc37" "IPR004918:Cdc37, IPR013855:Cdc37, N-terminal domain, IPR013873:Cdc37, C-terminal, IPR013874:Cdc37, Hsp90 binding" CG12019 27-Aug-18 DroID_v2018_08 "Drer\cdc37, Drer\cdc37l1" Scer\CDC37 "Cele\K07E8.6, Cele\cdc-37" "Xtro\cdc37l1, Xtro\cdc37" "Mmus\Cdc37l1, Mmus\Cdc37" "Hsap\CDC37, Hsap\CDC37L1" " embryonic stage | early , larval stage | third instar , embryonic stage | late " eye-antennal disc

"cell polarity defective,somatic clone,lethal - all die before end of second instar larval stage,some die during second instar larval stage,wild-type,lethal,recessive,meiotic cell cycle defective,cytokinesis defective,lethal - all die before end of larval stage,some die during larval stage,mitotic cell cycle defective,increased cell size,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "rhabdomere,somatic clone,eye photoreceptor cell,ommatidium,rhabdomere, with Df(3L)MY10,adult abdomen,spermatid,spindle,anaphase & condensed nuclear chromosome,actomyosin contractile ring,nucleus,mitosis & nuclear chromosome,embryonic/larval neuroblast,ganglion mother cell" DRSC08648 K 1.321519302 -0.414487054 0.296851587 0.138160272 -0.27233522 2.459577781 FBgn0015984 l(2)PC4-M lethal (2) PC4-M http://flybase.org/reports/FBgn0015984 - gene - - - "l(2)PC4-E, l(2)PC4-M" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0030260 CG1537 - http://flybase.org/reports/FBgn0030260 protein_coding_gene - - - "BcDNA:GH02938, CG1537" - CG1537 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0052702 Cubn Cubilin http://flybase.org/reports/FBgn0052702 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097" renal protein absorption ; GO:0097017 | inferred from mutant phenotype nephrocyte filtration ; GO:0097206 | inferred from mutant phenotype - "tok-like, CT7882, CG2996, CG32702, Cubn, dCubn" "IPR000152:EGF-type aspartate/asparagine hydroxylation site, IPR000742:EGF-like domain, IPR000859:CUB domain, IPR001881:EGF-like calcium-binding domain, IPR013032:EGF-like, conserved site, IPR009030:Growth factor receptor cysteine-rich domain, IPR018097:EGF-like calcium-binding, conserved site" CG32702 27-Aug-18 DroID_v2018_08 "Drer\tll1, Drer\mep1a.1, Drer\pcolce2b, Drer\he1a, Drer\LOC100003133, Drer\LOC797085, Drer\bmp1a, Drer\mep1b, Drer\c6ast4, Drer\tnfaip6, Drer\csmd2, Drer\he1b, Drer\pcolce2a, Drer\nrp1a, Drer\npsn, Drer\c6ast3, Drer\he2, Drer\bmp1b, Drer\nrp1b, Drer\c6ast1, Drer\mep1a.2, Drer\si:ch73-40a17.3, Drer\nrp2b, Drer\cubn" - "Cele\ZC116.3, Cele\nas-12, Cele\nas-7, Cele\nas-39, Cele\nas-13, Cele\nas-6, Cele\nas-14, Cele\nas-4, Cele\nas-15, Cele\nas-2, Cele\Y19D10A.6, Cele\nas-8, Cele\nas-1" "Xtro\tll1, Xtro\bmp1, Xtro\mep1b, Xtro\accs, Xtro\mep1a, Xtro\svep1, Xtro\tnfaip6, Xtro\LOC100489456, Xtro\LOC100492324, Xtro\uvs.2, Xtro\tll2, Xtro\cubn" "Mmus\Tll2, Mmus\Csmd1, Mmus\Adgrg6, Mmus\Bmp1, Mmus\Astl, Mmus\Tnfaip6, Mmus\Nrp2, Mmus\Pcolce, Mmus\Tll1, Mmus\Csmd2, Mmus\Csmd3, Mmus\Mep1b, Mmus\Svep1, Mmus\Nrp1, Mmus\Pcolce2, Mmus\Mep1a, Mmus\Cubn" "Hsap\CUBN, Hsap\NRP2, Hsap\NRP1, Hsap\MEP1B, Hsap\MEP1A, Hsap\TLL1, Hsap\SCUBE1, Hsap\ADGRG6, Hsap\BMP1, Hsap\PCOLCE, Hsap\CR1, Hsap\CSMD2, Hsap\CSMD3, Hsap\SVEP1, Hsap\TNFAIP6, Hsap\SCUBE2, Hsap\PCOLCE2, Hsap\CSMD1, Hsap\ASTL, Hsap\TLL2" "viable,chemical sensitive" embryonic/larval pericardial cell FBgn0002238 l(3)68Be lethal (3) 68Be http://flybase.org/reports/FBgn0002238 FBgn0002232 gene - - - "l(3)C28, C, l(3)C, l(3)68Be" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,heat sensitive" FBgn0030587 CG9522 - http://flybase.org/reports/FBgn0030587 protein_coding_gene "oxidoreductase activity, acting on CH-OH group of donors ; GO:0016614 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR007867, InterPro:IPR012132 flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR012132 oxidoreductase activity ; GO:0016491 | inferred from sequence or structural similarity with Eo" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR007867, InterPro:IPR012132, InterPro:IPR023753 ecdysteroid metabolic process ; GO:0045455 | inferred from sequence or structural similarity with Eo inferred from genomic context with Eo" - "CG9522, Dm GMCiota1" "IPR000172:Glucose-methanol-choline oxidoreductase, N-terminal, IPR007867:Glucose-methanol-choline oxidoreductase, C-terminal, IPR012132:Glucose-methanol-choline oxidoreductase, IPR023753:FAD/NAD(P)-binding domain" CG9522 27-Aug-18 DroID_v2018_08 Drer\chdh - Cele\C34C6.4 - Mmus\Chdh Hsap\CHDH viable FBgn0040365 CG14628 - http://flybase.org/reports/FBgn0040365 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity - - "EG:BACR42I17.12, cg14628, CG14628" IPR000504:RNA recognition motif domain CG14628 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-216l23.2, Drer\ncoa5" - - "Xtro\LOC100145527, Xtro\ncoa5" Mmus\Ncoa5 - viable FBgn0267817 lncRNA:CR46142 - http://flybase.org/reports/FBgn0267817 non_protein_coding_gene - - - CR46142 - CR46142 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0003943 Ubi-p63E Ubiquitin-63E http://flybase.org/reports/FBgn0003943 - protein_coding_gene protein tag ; GO:0031386 | inferred from sequence or structural similarity with SGD:S000003962 male meiosis I ; GO:0007141 | inferred from mutant phenotype larval midgut cell programmed cell death ; GO:0035096 | inferred from mutant phenotype ubiquitin homeostasis ; GO:0010992 | inferred from mutant phenotype protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with SGD:S000003962 autophagy ; GO:0006914 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype spermatid differentiation ; GO:0048515 | inferred from mutant phenotype microtubule associated complex ; GO:0005875 | inferred from direct assay "Ub, ubi63E, DmUb, CG11624, Ubi63E, Ubi-p, Ubp, Ubip, Ubi-p63E, Ubiq, Ubi63p, ubi, ubi-p63E, Ubi-P63e, DmUbi-p63E, Ubip63E, magn, UB, Ub-p63E" "IPR000626:Ubiquitin domain, IPR019954:Ubiquitin conserved site, IPR019956:Ubiquitin, IPR029071:Ubiquitin-related domain" CG11624 27-Aug-18 DroID_v2018_08 "Drer\zgc:56596, Drer\zfand4, Drer\faub, Drer\ubc, Drer\uba52, Drer\si:ch211-202a12.4, Drer\ubb, Drer\kxd1, Drer\isg15, Drer\faua, Drer\nedd8, Drer\nedd8l" Scer\UBI4 "Cele\F52C6.3, Cele\ubq-1, Cele\F52C6.2, Cele\ned-8, Cele\ubq-2, Cele\kxd-1" "Xtro\fau, Xtro\nedd8, Xtro\rps27a, Xtro\uba52, Xtro\kxd1, Xtro\ubl4a, Xtro\zfand4, Xtro\LOC100485835, Xtro\ubc" "Mmus\Oasl1, Mmus\Fau, Mmus\Oas1a, Mmus\Ubc, Mmus\Oas3, Mmus\Oas2, Mmus\Ubl4a, Mmus\Rps27a, Mmus\Zfand4, Mmus\Oasl2, Mmus\Nedd8, Mmus\Oas1g, Mmus\Ubl4b, Mmus\Ubd, Mmus\Isg15, Mmus\Ubb" "Hsap\OAS2, Hsap\UBD, Hsap\OASL, Hsap\UBC, Hsap\ZFAND4, Hsap\OAS1, Hsap\UBA52, Hsap\UBL4B, Hsap\OAS3, Hsap\RPS27A, Hsap\UBL4A, Hsap\UBB, Hsap\ISG15, Hsap\NEDD8" " embryonic stage -- adult stage , embryonic stage && larval stage && pupal stage "

"increased cell death,viable,fertile,male sterile,meiotic cell cycle defective,male limited,female fertile,cell autonomous,somatic clone" "testis,spermatocyte,cell autonomous,somatic clone" DRSC08703 IEK -2.616524024 -5.089831517 -0.197005128 -7.250994117 -7.566134038 -5.573509512 FBgn0036227 CG17826 - http://flybase.org/reports/FBgn0036227 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG17826 IPR002557:Chitin binding domain CG17826 27-Aug-18 DroID_v2018_08 Drer\thbd - "Cele\W03F11.1, Cele\R02F2.4, Cele\cbd-1, Cele\cpg-2" - - Hsap\MATN2 viable FBgn0243516 Vrp1 Verprolin 1 http://flybase.org/reports/FBgn0243516 protein_coding_gene actin filament binding ; GO:0051015 | inferred from direct assay regulation of cell shape ; GO:0008360 | inferred from mutant phenotype visceral muscle development ; GO:0007522 | inferred from mutant phenotype regulation of actin filament polymerization ; GO:0030833 | inferred from mutant phenotype positive regulation of actin filament polymerization ; GO:0030838 | inferred from direct assay myoblast fusion ; GO:0007520 | inferred from mutant phenotype spermatid development ; GO:0007286 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype actin filament organization ; GO:0007015 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay filopodium tip ; GO:0032433 | inferred from direct assay "wip, CG13503, Vrp1, sltr, D-WIP, solas, Dm_Vrp1, dWIP, vrp1, WIP, vrp, Sltr, DWIP" IPR003124:WH2 domain CG13503 27-Aug-18 DroID_v2018_08 "Drer\wipf1a, Drer\wipf2b, Drer\wipf1b, Drer\wipf2a, Drer\sb:cb649" Scer\VRP1 Cele\wip-1 "Xtro\wipf1, Xtro\wipf2" "Mmus\Wipf1, Mmus\Wipf2, Mmus\Wipf3" "Hsap\WIPF1, Hsap\WIPF2, Hsap\WIPF3" DRSC04148 I 0.547844328 -1.546639217 -1.340155535 -0.557923259 0.103537673 -0.36560665 FBgn0004806 fs(2)ltoRV64 female sterile (2) ltoRV64 http://flybase.org/reports/FBgn0004806 - gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(2)ltoRV64 - - 27-Aug-18 DroID_v2018_08 - - - - - - female sterile FBgn0016024 l(3)89Bm lethal (3) 89Bm http://flybase.org/reports/FBgn0016024 - gene - - - l(3)89Bm - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0261508 CG42656 - http://flybase.org/reports/FBgn0261508 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42656, DMG8-chr3R.6.013" - CG42656 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036008 CG3408 - http://flybase.org/reports/FBgn0036008 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "CT11439, CG3408" "IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like" CG3408 27-Aug-18 DroID_v2018_08 "Drer\lrrc59, Drer\lrrc18a, Drer\lrrc18b" - Cele\F56A8.3 "Xtro\lrrc59, Xtro\lrrc18" Mmus\Lrrc59 "Hsap\LRRC18, Hsap\LRRC59" viable FBgn0265811 asRNA:CR44600 - http://flybase.org/reports/FBgn0265811 non_protein_coding_gene - - - CR44600 - CR44600 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0019688 l(3)96Aa lethal (3) 96Aa http://flybase.org/reports/FBgn0019688 - gene - - - "291.5, l(3)96Aa" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,heat sensitive,some die during larval stage" FBgn0028017 l(3)S105307 lethal (3) S105307 http://flybase.org/reports/FBgn0028017 gene - - - "1053/07, l(3)S105307" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0264701 lncRNA:CR43970 - http://flybase.org/reports/FBgn0264701 non_protein_coding_gene - - - CR43970 - CR43970 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0061472 3R-I256 3R-I256 http://flybase.org/reports/FBgn0061472 gene - - - 3R-I256 - - 27-Aug-18 DroID_v2018_08 - - - - - - "neuron,somatic clone" FBgn0030109 CG12121 - http://flybase.org/reports/FBgn0030109 protein_coding_gene - - integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR009637 CG12121 IPR009637:Lung seven transmembrane receptor-like CG12121 27-Aug-18 DroID_v2018_08 "Drer\gpr107, Drer\LOC556363" - Cele\C15H9.5 Xtro\gpr107 "Mmus\Gpr107, Mmus\Gpr108" "Hsap\GPR107, Hsap\GPR108" FBgn0260576 MENE-WW14 - http://flybase.org/reports/FBgn0260576 gene - - - MENE-WW14 - - 27-Aug-18 DroID_v2018_08 - - - - - - "eye disc,somatic clone" FBgn0032101 CG9586 - http://flybase.org/reports/FBgn0032101 protein_coding_gene - - - CG9586 - CG9586 27-Aug-18 DroID_v2018_08 Drer\ccdc43 - - Xtro\ccdc43 Mmus\Ccdc43 Hsap\CCDC43 viable FBgn0054005 CG34005 - http://flybase.org/reports/FBgn0054005 protein_coding_gene - - - "BP1019, CG34005" IPR007931:Protein of unknown function DUF725 CG34005 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0261846 CG42778 - http://flybase.org/reports/FBgn0261846 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42778, lincRNA.767" - CG42778 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040375 CG13760 - http://flybase.org/reports/FBgn0040375 protein_coding_gene - - - "EG:BACR25B3.6, CG13760" IPR018616:Guanylyl cyclase CG13760 27-Aug-18 DroID_v2018_08 Drer\gucd1 - - Xtro\gucd1 Mmus\Gucd1 Hsap\GUCD1 "viable,visible" mesothoracic tergum FBgn0010217 ATPsynbeta "ATP synthase, beta subunit" http://flybase.org/reports/FBgn0010217 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000194, InterPro:IPR020003 proton-transporting ATP synthase activity, rotational mechanism ; GO:0046933 | contributes_to inferred from sequence or structural similarity with SGD:S000003882 proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from sequence or structural similarity with SGD:S000003882" regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype ATP synthesis coupled proton transport ; GO:0015986 | inferred from sequence or structural similarity with SGD:S000003882 proton transport ; GO:0015992 | inferred from sequence or structural similarity with UniProtKB:P06576 "lipid particle ; GO:0005811 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) ; GO:0000275 | inferred from sequence or structural similarity with UniProtKB:P06576" "ATP-syn-B, ATP, ATPsyn-b, CG11154, ATPsyn b, beta-ATPase, ATPB, ATPsyn-beta, ATPase beta, ATP-synbeta, ATPsyn-&bgr, ATPasebeta, ATP syn-beta, Comp V beta, ATPsynbeta, ATPase-beta, ATP-B, ATP-syn-beta" "IPR000194:ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain, IPR003593:AAA+ ATPase domain, IPR004100:ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain, IPR005722:ATP synthase, F1 complex, beta subunit, IPR024034:ATPase, F1/V1 complex, beta/alpha subunit, C-terminal, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR020003:ATPase, alpha/beta subunit, nucleotide-binding domain, active site" CG11154 27-Aug-18 DroID_v2018_08 "Drer\zgc:163069, Drer\atp5b" "Scer\ATP4, Scer\ATP2" "Cele\asb-2, Cele\atp-2, Cele\asb-1" Xtro\atp5b "Mmus\Atp5b, Mmus\Atp5f1" "Hsap\ATP5B, Hsap\ATP5F1" "lethal - all die before end of pupal stage,heat sensitive,some die during pupal stage,viable,female sterile,RU486 conditional,short lived,female,visible,partially lethal - majority die" "wing,adult thorax,chaeta" DRSC17194 K -0.919309664 0.132514835 -0.378673279 -0.049979443 1.08050153 2.743133277 FBgn0014941 anon-98Db anon-98Db http://flybase.org/reports/FBgn0014941 - gene - - - anon-98Db - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0069325 X-156-10 X-156-10 http://flybase.org/reports/FBgn0069325 gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available X-156-10 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0032934 CG8679 - http://flybase.org/reports/FBgn0032934 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG8679, dLEM3" "IPR002110:Ankyrin repeat, IPR003887:LEM domain, IPR011015:LEM/LEM-like domain, IPR020683:Ankyrin repeat-containing domain" CG8679 27-Aug-18 DroID_v2018_08 "Drer\zgc:85936, Drer\si:ch211-272n13.3" - "Cele\F44E5.15, Cele\lem-3, Cele\K07D4.2" Xtro\ankle1 "Mmus\Ankrd26, Mmus\Ankrd36, Mmus\4932414N04Rik, Mmus\Ankle1, Mmus\Ankrd7, Mmus\Ccdc144b, Mmus\4921524L21Rik" "Hsap\ANKLE1, Hsap\ANKRD62, Hsap\ANKRD20A4, Hsap\ANKRD20A1, Hsap\ANKRD30A, Hsap\ANKRD20A3, Hsap\ANKRD18B, Hsap\ANKRD26, Hsap\ANKRD20A2, Hsap\ANKRD18A, Hsap\ANKRD30B" viable FBgn0085578 CG41252 - http://flybase.org/reports/FBgn0085578 protein_coding_gene - - - CG41252 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001848 l(1)ts4975 lethal (1) ts4975 http://flybase.org/reports/FBgn0001848 - gene - - - l(1)ts4975 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,heat sensitive" FBgn0016815 l(1)L18 lethal (1) L18 http://flybase.org/reports/FBgn0016815 - gene - - - "l(1)L18, L18" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0033973 HPS1 Hermansky-Pudlak Syndrome 1 http://flybase.org/reports/FBgn0033973 protein_coding_gene molecular_function ; GO:0003674 | no biological data available phagocytosis ; GO:0006909 | inferred from mutant phenotype negative regulation of gene silencing by RNA ; GO:0060967 | inferred from mutant phenotype BLOC-3 complex ; GO:0031085 | inferred from sequence or structural similarity with HGNC:5163 BLOC-3 complex ; GO:0031085 | inferred from direct assay "CG12855, HPS1, dHPS1, HPS, NP_610997" IPR026053:Hermansky-Pudlak syndrome 1 protein CG12855 27-Aug-18 DroID_v2018_08 Drer\hps1 - "Cele\K04F1.9, Cele\E02H9.9, Cele\Y18H1A.8" - Mmus\Hps1 Hsap\HPS1 viable FBgn0032489 CG15480 - http://flybase.org/reports/FBgn0032489 protein_coding_gene - - - CG15480 - CG15480 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible" mesothoracic tergum DRSC02490 K -0.236220433 0.176035602 0.442982596 0.092155641 -0.699332014 -1.574464581 FBgn0035593 CG4603 - http://flybase.org/reports/FBgn0035593 protein_coding_gene thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from biological aspect of ancestor with PANTHER:PTN000329911 thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from sequence or structural similarity with HGNC:25035 protein deubiquitination ; GO:0016579 | inferred from biological aspect of ancestor with PANTHER:PTN000329911 endoplasmic reticulum unfolded protein response ; GO:0030968 | inferred from biological aspect of ancestor with PANTHER:PTN000329911 protein deubiquitination ; GO:0016579 | inferred from sequence or structural similarity with HGNC:25035 ER-associated ubiquitin-dependent protein catabolic process ; GO:0030433 | inferred from biological aspect of ancestor with PANTHER:PTN000329911 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000329911 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000329911 "CG4603, dYOD1, Q9VRJ9" "IPR003323:OTU domain, IPR029071:Ubiquitin-related domain" CG4603 27-Aug-18 DroID_v2018_08 Drer\yod1 Scer\OTU1 - Xtro\yod1 Mmus\Yod1 Hsap\YOD1 "viable,fertile,locomotor behavior defective" FBgn0036992 CG11796 - http://flybase.org/reports/FBgn0036992 protein_coding_gene 4-hydroxyphenylpyruvate dioxygenase activity ; GO:0003868 | inferred from biological aspect of ancestor with PANTHER:PTN000238554 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005956 tyrosine catabolic process ; GO:0006572 | inferred from biological aspect of ancestor with PANTHER:PTN000238554 endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN002279033 Golgi membrane ; GO:0000139 | inferred from biological aspect of ancestor with PANTHER:PTN002279033 CG11796 "IPR004360:Glyoxalase/fosfomycin resistance/dioxygenase domain, IPR005956:4-hydroxyphenylpyruvate dioxygenase, IPR029068:Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase" CG11796 27-Aug-18 DroID_v2018_08 "Drer\hip1, Drer\hpda, Drer\hpdb, Drer\hip1rb, Drer\hip1r" - "Cele\C31H2.4, Cele\Y18D10A.22, Cele\hpd-1" "Xtro\hip1r, Xtro\hpd, Xtro\hip1, Xtro\hpdl, Xtro\hpd" "Mmus\Hpd, Mmus\Hpdl, Mmus\Hip1r, Mmus\Hip1" "Hsap\HIP1R, Hsap\HIP1, Hsap\HPDL, Hsap\HPD" viable FBgn0015602 BEAF-32 Boundary element-associated factor of 32kD http://flybase.org/reports/FBgn0015602 FBgn0013752 protein_coding_gene DNA binding ; GO:0003677 | inferred from direct assay chromatin insulator sequence binding ; GO:0043035 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with dwg regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from direct assay chromatin organization ; GO:0006325 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype histone H3-K9 methylation ; GO:0051567 | inferred from direct assay polytene chromosome interband ; GO:0005705 | inferred from direct assay nuclear chromatin ; GO:0000790 | colocalizes_with inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "BEAF-32, Beaf-32, BEAF32B, BEAF32A, BEAF32, BEAF-32A, BEAF, CG10159, BEAF-32B, bs04c01.y1, beaf, BEAF32b, Beaf32" "IPR003656:Zinc finger, BED-type, IPR004210:BESS motif, IPR013087:Zinc finger C2H2-type" CG10159 27-Aug-18 DroID_v2018_08 - - - - - - "visible,increased cell death,viable,fertile,lethal,partially,enhancer of variegation,suppressor of variegation,poor,male fertile,female sterile,recessive,maternal effect,dominant,developmental rate defective,large body,lethal - all die before end of larval stage,some die during third instar larval stage" "ommatidium,interommatidial bristle,rhabdomereGMR.PS,eye disc,eye,polytene chromosome | third instar larval stageAB1,polytene chromosome | third instar larval stage34B,X chromosome | male,egg chamber,nurse cell,supernumerary,embryonic/larval fat body,polytene chromosome,imaginal disc,embryonic/larval central nervous system" FBgn0028211 l(3)S011001c lethal (3) S011001c http://flybase.org/reports/FBgn0028211 gene - - - "0110/01, l(3)S011001, l(3)S011001c" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0039195 CG17782 - http://flybase.org/reports/FBgn0039195 protein_coding_gene - - - CG17782 IPR006631:Protein of unknown function DM4/12 CG17782 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0023513 CG14803 - http://flybase.org/reports/FBgn0023513 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available replication fork processing ; GO:0031297 | inferred from sequence or structural similarity with HGNC:21475 double-strand break repair via homologous recombination ; GO:0000724 | inferred from sequence or structural similarity with HGNC:21475 nuclear replication fork ; GO:0043596 | inferred from sequence or structural similarity with HGNC:21475 "EG:63B12.9, CG14803" "IPR016024:Armadillo-type fold, IPR029424:MMS22-like, C-terminal, IPR029425:Protein MMS22-like, N-terminal" CG14803 27-Aug-18 DroID_v2018_08 Drer\mms22l - Cele\fbxa-190 Xtro\mms22l Mmus\Mms22l Hsap\MMS22L viable FBgn0267898 CR46186 - http://flybase.org/reports/FBgn0267898 pseudogene_attribute - - - CR46186 - CR46186 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263233 robls54B roadblock similar 54B http://flybase.org/reports/FBgn0263233 protein_coding_gene dynein intermediate chain binding ; GO:0045505 | inferred from biological aspect of ancestor with PANTHER:PTN000081506 microtubule-based movement ; GO:0007018 | inferred from biological aspect of ancestor with PANTHER:PTN000081506 dynein complex ; GO:0030286 | inferred from biological aspect of ancestor with PANTHER:PTN000081506 "CG34192, HDC06929, gene 3, GENE 3, robls54B" IPR004942:Roadblock/LAMTOR2 domain CG34192 27-Aug-18 DroID_v2018_08 "Drer\dynlrb1, Drer\si:ch211-147k9.8" - Cele\dyrb-1 "Xtro\dynlrb2, Xtro\dynlrb1" "Mmus\Dynlrb1, Mmus\Dynlrb2" "Hsap\DYNLRB1, Hsap\DYNLRB2" FBgn0028147 l(3)S045230 lethal (3) S045230 http://flybase.org/reports/FBgn0028147 gene - - - "0452/30, l(3)S045230" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0011616 l(1)I33f3-2 lethal (1) I33f3-2 http://flybase.org/reports/FBgn0011616 FBgn0010206 gene - - - "l(1)33f3, l(1)I33f3-2" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0266971 lncRNA:CR45422 - http://flybase.org/reports/FBgn0266971 non_protein_coding_gene - - - CR45422 - CR45422 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0016992 ms(3)1199A ms(3)1199A http://flybase.org/reports/FBgn0016992 - gene - - - ms(3)1199A - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034793 asrij asrij http://flybase.org/reports/FBgn0034793 protein_coding_gene - regulation of JAK-STAT cascade ; GO:0046425 | inferred from mutant phenotype lymph gland development ; GO:0048542 | inferred from mutant phenotype larval lymph gland hemopoiesis ; GO:0035167 | inferred from mutant phenotype embryonic hemopoiesis ; GO:0035162 | inferred from expression pattern inferred from mutant phenotype cytoplasmic vesicle ; GO:0031410 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay lysosome ; GO:0005764 | inferred from direct assay recycling endosome ; GO:0055037 | inferred from direct assay early endosome ; GO:0005769 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model "Dmasrij, CG13533, asrij, arj, Asrij, FBgn 34793" IPR009764:Ovarian carcinoma immunoreactive antigen CG13533 27-Aug-18 DroID_v2018_08 "Drer\ociad2, Drer\LOC553528, Drer\ociad1" - - "Xtro\ociad2, Xtro\ociad1" "Mmus\Ociad1, Mmus\Ociad2" "Hsap\OCIAD2, Hsap\OCIAD1" "developmental rate defective,viable,fertile,mitotic cell cycle defective" "secondary lobe of embryonic/larval lymph gland,ectopic | third instar larval stage,plasmatocyte,ectopic,embryonic/larval hemocyte,medullary zone of lymph gland primary lobe" DRSC04175 E -0.547016561 -0.662511057 -1.547508917 0.615120558 -0.020152039 -0.898850601 FBgn0030975 SdhBL "Succinate dehydrogenase, subunit B (iron-sulfur)-like" http://flybase.org/reports/FBgn0030975 protein_coding_gene "oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR004489 electron carrier activity ; GO:0009055 | inferred from electronic annotation with InterPro:IPR001041, InterPro:IPR025192 2 iron, 2 sulfur cluster binding ; GO:0051537 | inferred from electronic annotation with InterPro:IPR006058" "tricarboxylic acid cycle ; GO:0006099 | inferred from electronic annotation with InterPro:IPR004489 aerobic respiration ; GO:0009060 | inferred from biological aspect of ancestor with PANTHER:PTN000229864 respiratory electron transport chain ; GO:0022904 | inferred from biological aspect of ancestor with PANTHER:PTN000229864 mitochondrial electron transport, succinate to ubiquinone ; GO:0006121 | inferred from sequence or structural similarity with SdhB" mitochondrial membrane ; GO:0031966 | inferred from biological aspect of ancestor with PANTHER:PTN000229867 "CG7349, DHSB, SdhBL" "IPR025192:Succinate dehydogenase/fumarate reductase N-terminal, IPR001041:2Fe-2S ferredoxin-type iron-sulfur binding domain, IPR004489:Succinate dehydrogenase/fumarate reductase iron-sulphur protein, IPR006058:2Fe-2S ferredoxin, iron-sulphur binding site, IPR009051:Alpha-helical ferredoxin, IPR012675:Beta-grasp domain, IPR017896:4Fe-4S ferredoxin-type, iron-sulphur binding domain, IPR017900:4Fe-4S ferredoxin, iron-sulphur binding, conserved site" CG7349 27-Aug-18 DroID_v2018_08 Drer\sdhb Scer\SDH2 Cele\sdhb-1 Xtro\sdhb Mmus\Sdhb Hsap\SDHB FBgn0066355 l(3)51 lethal (3) 51 http://flybase.org/reports/FBgn0066355 gene - - - l(3)51 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0267766 asRNA:CR46097 - http://flybase.org/reports/FBgn0267766 non_protein_coding_gene - - - CR46097 - CR46097 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085452 CG34423 - http://flybase.org/reports/FBgn0085452 protein_coding_gene ATPase inhibitor activity ; GO:0042030 | inferred from biological aspect of ancestor with PANTHER:PTN000601270 ATPase binding ; GO:0051117 | inferred from biological aspect of ancestor with PANTHER:PTN000601270 negative regulation of ATPase activity ; GO:0032780 | inferred from biological aspect of ancestor with PANTHER:PTN000601270 heme biosynthetic process ; GO:0006783 | inferred from biological aspect of ancestor with PANTHER:PTN000601270 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000601269 "CG34423, anon-WO0118547.139, CG11079" IPR007648:Mitochondrial ATPase inhibitor CG34423 27-Aug-18 DroID_v2018_08 "Drer\atpif1b, Drer\atpif1a" - "Cele\mai-2, Cele\mai-1" Xtro\atpif1 Mmus\Atpif1 Hsap\ATPIF1 FBgn0036584 CG13054 - http://flybase.org/reports/FBgn0036584 protein_coding_gene - - - CG13054 IPR032050:Domain of unknown function DUF4797 CG13054 27-Aug-18 DroID_v2018_08 - - - - - - DRSC29594 K -0.640629146 -0.691996366 0.287765517 -0.32164358 1.72270192 0.714228883 FBgn0030038 CG1440 - http://flybase.org/reports/FBgn0030038 protein_coding_gene cysteine-type endopeptidase activity ; GO:0004197 | inferred from electronic annotation with InterPro:IPR004134 cysteine-type peptidase activity ; GO:0008234 | inferred from biological aspect of ancestor with PANTHER:PTN001621808 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR004134 response to toxic substance ; GO:0009636 | inferred from biological aspect of ancestor with PANTHER:PTN001621808 homocysteine catabolic process ; GO:0043418 | inferred from biological aspect of ancestor with PANTHER:PTN001621808 cytosol ; GO:0005829 | inferred from direct assay CG1440 "IPR000169:Cysteine peptidase, cysteine active site, IPR004134:Peptidase C1B, bleomycin hydrolase" CG1440 27-Aug-18 DroID_v2018_08 Drer\blmh Scer\LAP3 - Xtro\blmh Mmus\Blmh Hsap\BLMH viable FBgn0051004 mesh mesh http://flybase.org/reports/FBgn0051004 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VW87 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:O46101 cell-matrix adhesion ; GO:0007160 | inferred from electronic annotation with InterPro:IPR003886 smooth septate junction assembly ; GO:0090528 | inferred from mutant phenotype smooth septate junction ; GO:0005920 | inferred from direct assay "CG31004, CG15560, CT5150, CG12074, anon-WO0140519.233, mesh, Mesh" "IPR000436:Sushi/SCR/CCP domain, IPR001846:von Willebrand factor, type D domain, IPR003886:NIDO domain, IPR005533:AMOP domain, IPR014756:Immunoglobulin E-set, IPR013783:Immunoglobulin-like fold" CG31004 27-Aug-18 DroID_v2018_08 "Drer\LOC101882496, Drer\im:7156467, Drer\tecta, Drer\LOC100148750, Drer\sned1, Drer\si:ch73-329n5.6, Drer\adgrf6, Drer\si:ch73-105b23.6, Drer\zgc:112964" - "Cele\K03H1.5, Cele\R09E10.5, Cele\F54D1.6" Xtro\tecta.1 "Mmus\Adgrl4, Mmus\Sned1, Mmus\Susd2, Mmus\Tecta" "Hsap\MUC4, Hsap\SUSD2, Hsap\SNED1, Hsap\TECTA" "lethal,lethal - all die before end of first instar larval stage,some die during first instar larval stage,partially lethal - majority die,some die during pupal stage" "smooth septate junction | first instar larval stageExel6218),embryonic/larval midgut" FBgn0051494 tRNA:Gly-TCC-1-1 transfer RNA:Glycine-TCC 1-1 http://flybase.org/reports/FBgn0051494 tRNA_gene GGA codon-amino acid adaptor activity ; GO:0033463 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033463 cytosol ; GO:0005829 | inferred by curator from GO:0033463 "AE002699.trna11-GlyTCC, tRNA[Gly][[GGA]], tRNA:gly:84C, tRNA:G:84C, tRNA:G:TCC:AE002699-b, CR31494, chr3R.trna4-GlyTCC, tRNA-Gly-TCC-1-1, tRNA:Gly-TCC-1-1, tRNA:CR31494, GGA" - CR31494 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039078 CG4374 - http://flybase.org/reports/FBgn0039078 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - CG4374 IPR013087:Zinc finger C2H2-type CG4374 27-Aug-18 DroID_v2018_08 - Scer\AZF1 - - Mmus\Zfp770 Hsap\ZNF770 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0264750 CG44008 - http://flybase.org/reports/FBgn0264750 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from sequence model negative regulation of peptidase activity ; GO:0010466 | inferred from sequence model multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "CG31758, CG44008, CG42325" IPR002350:Kazal domain CG44008 27-Aug-18 DroID_v2018_08 "Drer\tmeff2a, Drer\tmeff1b, Drer\si:dkey-203a12.7, Drer\tmeff2b" - Cele\ZK813.6 Xtro\tmeff1 "Mmus\Tmeff2, Mmus\Tmeff1" "Hsap\TMEFF2, Hsap\TMEFF1" FBgn0085532 CG40894 - http://flybase.org/reports/FBgn0085532 protein_coding_gene - - - CG40894 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005301 mot-32l mottled 32l http://flybase.org/reports/FBgn0005301 - gene - - - mot-32l - - 27-Aug-18 DroID_v2018_08 - - - - - - "eye color defective,female,temperature conditional" "pigment cell,temperature conditional" FBgn0025583 IM2 Immune induced molecule 2 http://flybase.org/reports/FBgn0025583 "FBgn0034332, FBgn0044675, FBgn0047046" protein_coding_gene - defense response ; GO:0006952 | non-traceable author statement response to bacterium ; GO:0009617 | inferred from expression pattern defense response ; GO:0006952 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay extracellular region ; GO:0005576 | non-traceable author statement "DIM2, Im2, CG18106, BcDNA:RH08291, anon-WO0140519.2, IM2, DIM-2, DIM 2" IPR013172:Immune-induced protein Dim CG18106 27-Aug-18 DroID_v2018_08 - - - - - - adult stage viable FBgn0034473 Or56a Odorant receptor 56a http://flybase.org/reports/FBgn0034473 protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from direct assay odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 "56a, DOR59, CG12501, 56E.1, Or56a" "IPR004117:Olfactory receptor, insect" CG12501 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0267241 lncRNA:CR45681 - http://flybase.org/reports/FBgn0267241 non_protein_coding_gene - - - CR45681 - CR45681 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262430 mir-9c mir-9c stem loop http://flybase.org/reports/FBgn0262430 miRNA_gene - germ cell development ; GO:0007281 | inferred from mutant phenotype - "miR-9c, mir-9c, dme-mir-9c, 9c, MIR-9, CR42985, CR33564, miR-9, mir-9C, mir-9, MiR-9c, dme-miR-9c-5p, dme-miR-9c" - CR42985 27-Aug-18 DroID_v2018_08 - - - - - - embryonic stage -- adult stage "lethal,visible" "eye,wing,wing margin,wing margin bristle,germline cell,maternal effect" FBgn0024499 Acprep1 Accessory gland protein rep1 http://flybase.org/reports/FBgn0024499 - gene - - - "Acp rep1, Acprep1" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259458 EP-654a - http://flybase.org/reports/FBgn0259458 gene - - - EP-654a - - 27-Aug-18 DroID_v2018_08 - - - - - - visible wing FBgn0030598 CG9503 - http://flybase.org/reports/FBgn0030598 protein_coding_gene "flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR012132 oxidoreductase activity, acting on CH-OH group of donors ; GO:0016614 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR007867, InterPro:IPR012132 oxidoreductase activity ; GO:0016491 | inferred from sequence or structural similarity with Eo" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR007867, InterPro:IPR012132, InterPro:IPR023753 ecdysteroid metabolic process ; GO:0045455 | inferred from sequence or structural similarity with Eo inferred from genomic context with Eo" - "CG9503, Dm GMCalpha1" "IPR000172:Glucose-methanol-choline oxidoreductase, N-terminal, IPR007867:Glucose-methanol-choline oxidoreductase, C-terminal, IPR012132:Glucose-methanol-choline oxidoreductase, IPR023753:FAD/NAD(P)-binding domain" CG9503 27-Aug-18 DroID_v2018_08 Drer\chdh - Cele\C34C6.4 - Mmus\Chdh Hsap\CHDH FBgn0008647 S63 S63 http://flybase.org/reports/FBgn0008647 - gene - - - "S 63, S63" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0044099 E(rst)C6 E(rst)C6 http://flybase.org/reports/FBgn0044099 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "C6, E(rst)C6" - - 27-Aug-18 DroID_v2018_08 - - - - - - viable eye FBgn0025920 l(3)78Ae lethal (3) 78Ae http://flybase.org/reports/FBgn0025920 - gene - - - l(3)78Ae - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0002786 mot-36e mottled 36e http://flybase.org/reports/FBgn0002786 - gene - - - mot-36e - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,visible,eye color defective" "pigment cell,wing,wing vein,posterior crossvein,macrochaeta,microchaeta" FBgn0039735 Nph Nucleophosmin http://flybase.org/reports/FBgn0039735 protein_coding_gene histone binding ; GO:0042393 | inferred from direct assay chromatin remodeling ; GO:0006338 | inferred from direct assay sperm chromatin decondensation ; GO:0035041 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG7911, Nph" "IPR004301:Nucleoplasmin family, IPR024057:Nucleoplasmin core domain" CG7911 27-Aug-18 DroID_v2018_08 "Drer\npm2a, Drer\npm2b, Drer\npm1a, Drer\npm1b" - - "Xtro\npm1, Xtro\npm2, Xtro\npm3" "Mmus\Npm2, Mmus\Npm1, Mmus\Npm3" "Hsap\NPM3, Hsap\NPM2, Hsap\NPM1" FBgn0000092 CG2650 - http://flybase.org/reports/FBgn0000092 - protein_coding_gene - circadian rhythm ; GO:0007623 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from sequence or structural similarity with to "anon-3B1.2, EG:155E2.1, 0.9, 0.9 gene, CG2650" IPR010562:Haemolymph juvenile hormone binding CG2650 27-Aug-18 DroID_v2018_08 - - - - - - " adult stage , pupal stage " " epidermis

, epidermis

{ 0 per* } " viable FBgn0014350 ms(2)HB40 ms(2)HB40 http://flybase.org/reports/FBgn0014350 - gene - - - ms(2)HB40 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0041737 l(3)63Ef lethal (3) 63Ef http://flybase.org/reports/FBgn0041737 gene - - - "group I, l(3)63Ef" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0264006 dysc dyschronic http://flybase.org/reports/FBgn0264006 protein_coding_gene molecular_function ; GO:0003674 | no biological data available sensory perception of light stimulus ; GO:0050953 | inferred from electronic annotation with InterPro:IPR033028 sensory perception of sound ; GO:0007605 | inferred from electronic annotation with InterPro:IPR033028 regulation of synaptic growth at neuromuscular junction ; GO:0008582 | inferred from mutant phenotype rhabdomere development ; GO:0042052 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | inferred from mutant phenotype muscle cell cellular homeostasis ; GO:0046716 | inferred from mutant phenotype inferred from genetic interaction with Dg inferred from genetic interaction with Dys positive regulation of ion transmembrane transporter activity ; GO:0032414 | inferred from mutant phenotype negative regulation of neuromuscular synaptic transmission ; GO:1900074 | inferred from mutant phenotype photoreceptor cell axon guidance ; GO:0072499 | inferred from mutant phenotype synapse ; GO:0045202 | inferred from direct assay "CG34400, CG32132, CG17368, CG8760, anon-AE003536.1, CG32131, Dm_3L:69335, dysc, CG43749" "IPR033028:Whirlin, IPR001478:PDZ domain" CG43749 27-Aug-18 DroID_v2018_08 "Drer\pard3bb, Drer\pdzd7a, Drer\il16, Drer\grip2b, Drer\grid2ipa, Drer\dfnb31a, Drer\si:dkey-92i15.4, Drer\lnx1, Drer\slc9a3r1, Drer\dfnb31b, Drer\dlg5a, Drer\inadl, Drer\pdzd7b, Drer\grip1" - "Cele\dlg-1, Cele\ZK849.1" "Xtro\grip1, Xtro\dlg5, Xtro\dfnb31, Xtro\grid2ip, Xtro\pdzd7, Xtro\grip2, Xtro\lnx1" "Mmus\Patj, Mmus\Dlg5, Mmus\Grip1, Mmus\Mpdz, Mmus\Whrn, Mmus\Grasp, Mmus\Grid2ip, Mmus\Pdzd7, Mmus\Pdzd11, Mmus\Pdzd2, Mmus\Ush1c, Mmus\Lnx1, Mmus\Pdzph1, Mmus\Il16, Mmus\Grip2" "Hsap\WHRN, Hsap\IL16, Hsap\GRIP1, Hsap\PARD3B, Hsap\PDZD2, Hsap\FRMPD2, Hsap\GRASP, Hsap\DLG5, Hsap\MPDZ, Hsap\USH1C, Hsap\PDZD7, Hsap\PATJ, Hsap\LNX1, Hsap\GRID2IP" FBgn0003543 stu small tumoroid http://flybase.org/reports/FBgn0003543 - gene - - - stu - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,male,poor,male fertile,visible,melanotic mass phenotype" melanotic mass FBgn0260760 CG42558 - http://flybase.org/reports/FBgn0260760 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG7866, CG42558" - CG42558 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034650 NC2alpha Negative Cofactor 2alpha http://flybase.org/reports/FBgn0034650 protein_coding_gene "protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 transcription factor binding ; GO:0008134 | inferred from physical interaction with NC2β protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VJQ5 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly ; GO:0001075 | contributes_to inferred from physical interaction with NC2β" "positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from direct assay" nucleus ; GO:0005634 | inferred by curator from GO:0001075 "dDrap1, Drap1, dDrap1/dNC2a, dDrap, dNC2, CG10318, NC2alpha, NC2, Nc2alpha" "IPR003958:Transcription factor CBF/NF-Y/archaeal histone domain, IPR009072:Histone-fold" CG10318 27-Aug-18 DroID_v2018_08 "Drer\LOC100535468, Drer\drap1" Scer\BUR6 Cele\drap-1 Xtro\drap1 Mmus\Drap1 Hsap\DRAP1 "viable,visible" mesothoracic tergum FBgn0050471 CG30471 - http://flybase.org/reports/FBgn0050471 protein_coding_gene "transferase activity, transferring acyl groups other than amino-acyl groups ; GO:0016747 | inferred from electronic annotation with InterPro:IPR002656" - - "CG8185, CG30471" "IPR002656:Acyltransferase 3, IPR006621:Nose resistant-to-fluoxetine protein, N-terminal" CG30471 27-Aug-18 DroID_v2018_08 Drer\oacyl - "Cele\oac-7, Cele\oac-53, Cele\oac-32, Cele\oac-31, Cele\oac-46, Cele\oac-20, Cele\oac-9, Cele\oac-54, Cele\oac-6, Cele\oac-55, Cele\oac-14, Cele\ndg-4, Cele\oac-50, Cele\oac-39, Cele\nrf-6, Cele\oac-5, Cele\oac-3, Cele\rhy-1" - Mmus\Oacyl - viable FBgn0260606 2L1540 - http://flybase.org/reports/FBgn0260606 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L1540 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0263022 CG43317 - http://flybase.org/reports/FBgn0263022 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43317, CG14876" - CG43317 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036997 CG5955 - http://flybase.org/reports/FBgn0036997 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR001509 coenzyme binding ; GO:0050662 | inferred from electronic annotation with InterPro:IPR001509 - - CG5955 "IPR001509:NAD-dependent epimerase/dehydratase, IPR016040:NAD(P)-binding domain" CG5955 27-Aug-18 DroID_v2018_08 "Drer\tdh, Drer\tdh2" - Cele\F08F3.4 Xtro\LOC101730350 Mmus\Tdh Hsap\TGDS "viable,body color defective" mesothoracic tergum FBgn0019687 l(3)LG12 lethal (3) LG12 http://flybase.org/reports/FBgn0019687 - gene - - - l(3)LG12 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0030390 CG15731 - http://flybase.org/reports/FBgn0030390 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15731 IPR031903:Domain of unknown function DUF4766 CG15731 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" FBgn0027290 l(1)G0161 lethal (1) G0161 http://flybase.org/reports/FBgn0027290 - gene - - - l(1)G0161 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,female,recessive" FBgn0267065 lncRNA:CR45509 - http://flybase.org/reports/FBgn0267065 non_protein_coding_gene - - - CR45509 - CR45509 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0043846 412\ORF4 412 element ORF4 http://flybase.org/reports/FBgn0043846 transposable_element_gene - - - "412\ORF4, ORF4" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085494 Mst77Y-16Psi Male-specific pseudogene 77Y 16 http://flybase.org/reports/FBgn0085494 pseudogene_attribute - - - "Mst77Y-16Psi, CG40530" - CR40530 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039630 CG11843 - http://flybase.org/reports/FBgn0039630 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP43, CG11843" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG11843 27-Aug-18 DroID_v2018_08 Drer\masp2 - "Cele\try-3, Cele\try-1, Cele\svh-1" - "Mmus\Plat, Mmus\Plau, Mmus\Habp2, Mmus\Prss12, Mmus\F12, Mmus\Hgfac" - "viable,fertile" FBgn0027935 vu vesuvio http://flybase.org/reports/FBgn0027935 gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available vu - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266309 lncRNA:CR44974 - http://flybase.org/reports/FBgn0266309 non_protein_coding_gene - - - CR44974 - CR44974 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005514 l(2)25Ea lethal (2) 25Ea http://flybase.org/reports/FBgn0005514 - gene - - - "jf25, l(2)gdh-11, l(2)jf25, l(2)gdh11, l(2)25Ea" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0033551 CG7222 - http://flybase.org/reports/FBgn0033551 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG7222 IPR008580:PPPDE putative peptidase domain CG7222 27-Aug-18 DroID_v2018_08 "Drer\desi1a, Drer\desi2, Drer\LOC794838, Drer\desi1b" - Cele\F36D4.5 "Xtro\desi1, Xtro\desi2" "Mmus\Desi2, Mmus\Desi1" "Hsap\DESI2, Hsap\DESI1" "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0015975 l(2)PC4-A lethal (2) PC4-A http://flybase.org/reports/FBgn0015975 - gene - - - l(2)PC4-A - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0039958 CG12567 - http://flybase.org/reports/FBgn0039958 protein_coding_gene 8-oxo-dGDP phosphatase activity ; GO:0044715 | inferred from biological aspect of ancestor with PANTHER:PTN000341541 - - CG12567 "IPR000086:NUDIX hydrolase domain, IPR015797:NUDIX hydrolase domain-like, IPR031804:Domain of unknown function DUF4743" CG12567 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-6n6.2, Drer\tpk1" "Scer\THI80, Scer\YJR142W" Cele\tpk-1 - Mmus\Tpk1 Hsap\TPK1 FBgn0028180 l(3)S024535b lethal (3) S024535b http://flybase.org/reports/FBgn0028180 gene - - - "88A, 0245/35, l(3)S024535, l(3)S024535b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0030041 CG12116 - http://flybase.org/reports/FBgn0030041 protein_coding_gene - - - "CG12116, 144701_at" "IPR016040:NAD(P)-binding domain, IPR002347:Short-chain dehydrogenase/reductase SDR" CG12116 27-Aug-18 DroID_v2018_08 "Drer\spra, Drer\sprb" "Scer\YIR035C, Scer\IRC24" "Cele\C01G12.5, Cele\F02C12.2" - Mmus\Spr Hsap\SPR viable FBgn0051516 CG31516 - http://flybase.org/reports/FBgn0051516 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE68446, CG31516" IPR031941:Domain of unknown function DUF4773 CG31516 27-Aug-18 DroID_v2018_08 - - Cele\C09D4.2 - - - viable FBgn0046325 ms(2)38DEa ms(2)38DEa http://flybase.org/reports/FBgn0046325 gene - - - "ms in 38D/E, ms(2)38DEa" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060871 l(3)S047003 lethal (3) S047003 http://flybase.org/reports/FBgn0060871 gene - - - "0470/03, l(3)S047003" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0027181 l(2)60A-M lethal (2) 60A-M http://flybase.org/reports/FBgn0027181 - gene - - - l(2)60A-M - - 27-Aug-18 DroID_v2018_08 - - - - - - "wild-type,lethal,recessive" FBgn0005006 dfi deformed eye http://flybase.org/reports/FBgn0005006 - gene - - - dfi - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,viable,male,poor,female sterile,recessive" eye FBgn0034634 CG10494 - http://flybase.org/reports/FBgn0034634 protein_coding_gene - - - CG10494 - CG10494 27-Aug-18 DroID_v2018_08 Drer\zgc:113263 - - - Mmus\Msantd2 Hsap\MSANTD2 "partially lethal - majority die,some die during pupal stage" FBgn0069127 mei(3)M20 mei(3)M20 http://flybase.org/reports/FBgn0069127 gene - male meiosis chromosome segregation ; GO:0007060 | inferred from mutant phenotype - mei(3)M20 - - 27-Aug-18 DroID_v2018_08 - - - - - - "meiotic cell cycle defective,male,recessive,female semi-sterile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" FBgn0265884 lncRNA:CR44673 - http://flybase.org/reports/FBgn0265884 non_protein_coding_gene - - - CR44673 - CR44673 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265868 lncRNA:CR44657 - http://flybase.org/reports/FBgn0265868 non_protein_coding_gene - - - "lincRNA.993, CR44657" - CR44657 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030278 CG15200 - http://flybase.org/reports/FBgn0030278 protein_coding_gene - sperm competition ; GO:0046692 | inferred from mutant phenotype - CG15200 - CG15200 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0039197 CG17780 - http://flybase.org/reports/FBgn0039197 protein_coding_gene - - - "CG17780, BcDNA:RE41041" IPR006631:Protein of unknown function DM4/12 CG17780 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0025123 su(RpII140[Z36])S5 su(RpII140[Z36])S5 http://flybase.org/reports/FBgn0025123 - gene - - - "Z36[S5], su(RpII140[Z36])S5" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263289 scrib scribbled http://flybase.org/reports/FBgn0263289 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with gukh "signal transduction ; GO:0007165 |... biological aspect of ancestor with PANTHER:PTN002351852 <> cell fate commitment involved in pattern specification ; GO:0060581 |... mutant phenotype <> regulation of synapse structure or activity ; GO:0050803 |... mutant phenotype <> cell proliferation ; GO:0008283 |... mutant phenotype <> compound eye development ; GO:0048749 |... mutant phenotype <> olfactory behavior ; GO:0042048 |... mutant phenotype <> cell fate specification ; GO:0001708 |... mutant phenotype <> negative regulation of epithelial cell proliferation ; GO:0050680 |... mutant phenotype <> dorsal closure ; GO:0007391 | traceable author statement <> establishment or maintenance of epithelial cell apical/basal polarity ; GO:0045197 | non-traceable author statement <> Malpighian tubule development ; GO:0072002 |... mutant phenotype <> dorsal closure ; GO:0007391 |... mutant phenotype <> memory ; GO:0007613 |... mutant phenotype <> establishment of ommatidial planar polarity ; GO:0042067 |... mutant phenotype <> cell morphogenesis ; GO:0000902 |... mutant phenotype <> regulation of epidermal growth factor receptor signaling pathway ; GO:0042058 |... mutant phenotype <> establishment of imaginal disc-derived wing hair orientation ; GO:0001737 |... mutant phenotype <> negative regulation of cell proliferation ; GO:0008285 |... mutant phenotype <> wing disc morphogenesis ; GO:0007472 |... mutant phenotype <> zonula adherens assembly ; GO:0045186 |... mutant phenotype <> septate junction assembly ; GO:0019991 |... mutant phenotype <> regulation of endocytosis ; GO:0030100 |... mutant phenotype <> asymmetric protein localization ; GO:0008105 |... mutant phenotype <> regulation of Notch signaling pathway ; GO:0008593 |... mutant phenotype <> establishment of epithelial cell apical/basal polarity ; GO:0045198 |... mutant phenotype <> morphogenesis of larval imaginal disc epithelium ; GO:0016335 |... mutant phenotype <> stem cell differentiation ; GO:0048863 |... mutant phenotype <> establishment or maintenance of polarity of follicular epithelium ; GO:0016334 |... mutant phenotype <> negative regulation of imaginal disc growth ; GO:0045571 |... mutant phenotype <> R3/R4 cell fate commitment ; GO:0007464 |... mutant phenotype <> establishment or maintenance of epithelial cell apical/basal polarity ; GO:0045197 | traceable author statement <> maintenance of epithelial cell apical/basal polarity ; GO:0045199 |... biological aspect of ancestor with PANTHER:PTN002352077 <> morphogenesis of embryonic epithelium ; GO:0016331 | traceable author statement <> establishment or maintenance of polarity of larval imaginal disc epithelium ; GO:0016336 |... mutant phenotype <> establishment or maintenance of apical/basal cell polarity ; GO:0035088 |... mutant phenotype <> establishment or maintenance of polarity of embryonic epithelium ; GO:0016332 | traceable author statement <> stem cell proliferation ; GO:0072089 |... mutant phenotype <> morphogenesis of follicular epithelium ; GO:0016333 |... mutant phenotype <> regulation of cell cycle ; GO:0051726 | non-traceable author statement <> asymmetric protein localization ; GO:0008105 | traceable author statement <> negative regulation of cell proliferation ; GO:0008285 | traceable author statement <> morphogenesis of a polarized epithelium ; GO:0001738 | traceable author statement <> anterior/posterior axis specification, follicular epithelium ; GO:0030714 |... mutant phenotype <> negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 |... mutant phenotype <> pole plasm protein localization ; GO:0007318 |... mutant phenotype <> ovarian follicle cell development ; GO:0030707 |... mutant phenotype <> regulation of JAK-STAT cascade ; GO:0046425 |... mutant phenotype" basolateral plasma membrane ; GO:0016323 | inferred from direct assay septate junction ; GO:0005918 | inferred from direct assay basolateral plasma membrane ; GO:0016323 | traceable author statement septate junction ; GO:0005918 | traceable author statement septate junction ; GO:0005918 | non-traceable author statement neuromuscular junction ; GO:0031594 | inferred from direct assay apicolateral plasma membrane ; GO:0016327 | inferred from direct assay fusome ; GO:0045169 | inferred from direct assay lateral plasma membrane ; GO:0016328 | inferred from direct assay "scrib, Scrib, CG43398, scrb, CG5462, CG42614, smi97B, ird15, SCR, CT17324, ird, vart, l(3)673, l(3)j7B3, l(3)S042405, 0424/05, l(3)c00119, Scrb, Scb, MENE (3R)-F, CG5467, CG31082" "IPR032675:Leucine-rich repeat domain, L domain-like, IPR001478:PDZ domain, IPR001611:Leucine-rich repeat, IPR015943:WD40/YVTN repeat-like-containing domain, IPR003591:Leucine-rich repeat, typical subtype" CG43398 27-Aug-18 DroID_v2018_08 "Drer\scrib, Drer\lrrc1" - "Cele\magi-1, Cele\Y42G9A.3, Cele\let-413" "Xtro\scrib, Xtro\lrrc1" "Mmus\Scrib, Mmus\Lrrd1, Mmus\Lrrc1, Mmus\Lrch4, Mmus\Tjp1" "Hsap\SCRIB, Hsap\LRRC1, Hsap\TJP1, Hsap\LRRD1, Hsap\LRCH4" " adult stage | female , adult stage , pupal stage , adult stage | male , larval stage | female , larval stage | male , embryonic stage | 0-24hr , embryonic stage | 0-6hr , larval stage , embryonic stage | 9-22hr , embryonic stage | late " " antennal segment 3

, antennal segment 2

, maxillary palpus

, adult brain | restricted

, organism

, Johnston's organ

" " embryonic stage | stage 16,17 , embryonic stage | stage 15,16 , embryonic stage | late , embryonic stage | 0-12hr , embryonic stage | mid-late , embryonic stage | early , adult stage , embryonic stage | mid , embryonic stage | stage 16-17 , embryonic stage | 12-24hr " " ventral nerve cord commissure

, pole cell

, cell body

, ventral nerve cord

, ventral midline

, embryonic sensory system

, embryonic peripheral nervous system

,

ubiquitous , protocerebrum

, neuroblast

, neuron

, longitudinal connective

, antenna

, embryonic central nervous system

, maxillary palpus

, gonad

, adult brain | restricted

" FBgn0265381 lncRNA:CR44322 - http://flybase.org/reports/FBgn0265381 non_protein_coding_gene - - - CR44322 - CR44322 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266769 lncRNA:CR45234 - http://flybase.org/reports/FBgn0266769 non_protein_coding_gene - - - "CR45234, lincRNA.599" - CR45234 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0042164 CG18844 - http://flybase.org/reports/FBgn0042164 protein_coding_gene - - - CG18844 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039386 CG5948 - http://flybase.org/reports/FBgn0039386 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000000113 copper ion binding ; GO:0005507 | inferred from biological aspect of ancestor with PANTHER:PTN000000113 superoxide dismutase activity ; GO:0004784 | inferred from biological aspect of ancestor with PANTHER:PTN000000113 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001424 removal of superoxide radicals ; GO:0019430 | inferred from biological aspect of ancestor with PANTHER:PTN000000113 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000000114 CG5948 "IPR001424:Superoxide dismutase, copper/zinc binding domain" CG5948 27-Aug-18 DroID_v2018_08 "Drer\sod1, Drer\sod3a" Scer\SOD1 "Cele\sod-4, Cele\sod-1, Cele\sod-5" "Xtro\sod1, Xtro\sod3" "Mmus\Sod1, Mmus\Sod3" "Hsap\SOD1, Hsap\SOD3" FBgn0051955 CG31955 - http://flybase.org/reports/FBgn0051955 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available CG31955 - CG31955 27-Aug-18 DroID_v2018_08 Drer\chtf18 Scer\CTF18 - Xtro\chtf18 Mmus\Chtf18 Hsap\CHTF18 viable FBgn0025931 hip57 hb-interacting protein 57 http://flybase.org/reports/FBgn0025931 - gene - - - hip57 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266873 lncRNA:CR45334 - http://flybase.org/reports/FBgn0266873 non_protein_coding_gene - - - CR45334 - CR45334 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260808 EP3-1199 - http://flybase.org/reports/FBgn0260808 gene - - - EP3-1199 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264375 lncRNA:CR43827 - http://flybase.org/reports/FBgn0264375 non_protein_coding_gene - - - CR43827 - CR43827 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037128 CG14572 - http://flybase.org/reports/FBgn0037128 protein_coding_gene - - - CG14572 IPR032011:Domain of unknown function DUF4794 CG14572 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0265785 CG44574 - http://flybase.org/reports/FBgn0265785 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44574 - CG44574 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035069 CG3611 - http://flybase.org/reports/FBgn0035069 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT12780, CG3611" - CG3611 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0053181 CG33181 - http://flybase.org/reports/FBgn0053181 protein_coding_gene cation transmembrane transporter activity ; GO:0008324 | inferred from electronic annotation with InterPro:IPR006667 cation transport ; GO:0006812 | inferred from electronic annotation with InterPro:IPR006667 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN001045280 - "CG1521, CG33181, CG32714" "IPR006667:SLC41 divalent cation transporters, integral membrane domain" CG33181 27-Aug-18 DroID_v2018_08 "Drer\slc41a2b, Drer\LOC564564, Drer\slc41a2a, Drer\slc41a1" - "Cele\ZK1053.6, Cele\ZK185.2, Cele\K07H8.2" "Xtro\slc41a2, Xtro\slc41a3" "Mmus\Slc41a3, Mmus\Slc41a2, Mmus\Slc41a1" "Hsap\SLC41A3, Hsap\SLC41A1, Hsap\SLC41A2" viable FBgn0266732 asRNA:CR45205 - http://flybase.org/reports/FBgn0266732 non_protein_coding_gene - - - CR45205 - CR45205 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031518 CG3277 - http://flybase.org/reports/FBgn0031518 protein_coding_gene "protein tyrosine kinase activity ; GO:0004713 | inferred from electronic annotation with InterPro:IPR020635 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 protein tyrosine kinase activity ; GO:0004713 | non-traceable author statement" "protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR001245, InterPro:IPR008266, InterPro:IPR020635 protein phosphorylation ; GO:0006468 | non-traceable author statement" cellular_component ; GO:0005575 | no biological data available CG3277 "IPR000719:Protein kinase domain, IPR008266:Tyrosine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR020635:Tyrosine-protein kinase, catalytic domain, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain" CG3277 27-Aug-18 DroID_v2018_08 "Drer\si:ch73-206d17.1, Drer\fgfr3, Drer\fgfrl1a, Drer\kdr, Drer\si:dkey-14o18.6, Drer\kita, Drer\tie1, Drer\pdgfrl, Drer\flt4, Drer\si:ch211-167j9.5, Drer\tada2b, Drer\csf1ra, Drer\styk1, Drer\fgfr1a, Drer\flt3, Drer\ret, Drer\kitb, Drer\tek, Drer\kdrl, Drer\csf1rb, Drer\pdgfra, Drer\pdgfrb, Drer\fgfr2, Drer\fgfr4, Drer\LOC569566, Drer\flt1, Drer\fgfrl1b" - "Cele\egl-15, Cele\kin-9, Cele\F09G2.1, Cele\ver-4, Cele\R151.1, Cele\F09A5.2, Cele\C24G6.2" "Xtro\fgfr1, Xtro\pdgfra, Xtro\fgfr3, Xtro\pdgfrl.2, Xtro\flt1, Xtro\csf1r, Xtro\tie1, Xtro\kdr, Xtro\fgfr4, Xtro\fgfrl1, Xtro\tada2b, Xtro\pdgfrl, Xtro\fgfr2, Xtro\styk1, Xtro\tek, Xtro\flt4, Xtro\ret" "Mmus\Tie1, Mmus\Fgfr1, Mmus\Fgfr4, Mmus\Tek, Mmus\Kdr, Mmus\Pdgfrb, Mmus\Fgfr2, Mmus\Flt4, Mmus\Flt3, Mmus\Tada2b, Mmus\Styk1, Mmus\Fgfr3, Mmus\Ret, Mmus\Kit, Mmus\Pdgfrl, Mmus\Csf1r, Mmus\Pdgfra, Mmus\Flt1, Mmus\Fgfrl1" "Hsap\FLT1, Hsap\FLT4, Hsap\KIT, Hsap\RET, Hsap\PDGFRL, Hsap\PDGFRB, Hsap\FGFR1, Hsap\TIE1, Hsap\TEK, Hsap\FGFR2, Hsap\FGFR4, Hsap\PDGFRA, Hsap\FGFR3, Hsap\FGFRL1, Hsap\TADA2B, Hsap\CSF1R, Hsap\KDR, Hsap\FLT3, Hsap\STYK1" viable FBgn0030749 AnxB11 Annexin B11 http://flybase.org/reports/FBgn0030749 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001464, InterPro:IPR018252, InterPro:IPR018502 actin binding ; GO:0003779 | inferred from sequence or structural similarity calcium-dependent phospholipid binding ; GO:0005544 | inferred from sequence or structural similarity with AnxB10" cell adhesion ; GO:0007155 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "Anxb11, CG9968, BcDNA:GH16395, AnxB11, annexin, ANXB11" "IPR001464:Annexin, IPR018252:Annexin repeat, conserved site, IPR018502:Annexin repeat" CG9968 27-Aug-18 DroID_v2018_08 "Drer\anxa4, Drer\anxa1a, Drer\anxa3a, Drer\anxa3b, Drer\anxa5a, Drer\anxa11b, Drer\LOC103908630, Drer\anxa11a, Drer\anxa13l, Drer\zgc:110283, Drer\anxa6, Drer\anxa2a, Drer\anxa5b, Drer\prnprs3, Drer\anxa13, Drer\anxa1b, Drer\zgc:101785, Drer\anxa1c, Drer\anxa2b" - "Cele\nex-4, Cele\nex-2, Cele\nex-1, Cele\nex-3" "Xtro\anxa1, Xtro\anxa7, Xtro\anxa6, Xtro\anxa8, Xtro\anxa13, Xtro\anxa2, Xtro\anxa4, Xtro\anxa11, Xtro\anxa5, Xtro\anxa3" "Mmus\Anxa8, Mmus\Anxa1, Mmus\Anxa10, Mmus\Anxa9, Mmus\Anxa11, Mmus\Anxa3, Mmus\Anxa4, Mmus\Anxa7, Mmus\Anxa6, Mmus\Anxa2, Mmus\Anxa5" "Hsap\ANXA2, Hsap\ANXA4, Hsap\ANXA13, Hsap\ANXA6, Hsap\ANXA7, Hsap\ANXA3, Hsap\ANXA11, Hsap\ANXA9, Hsap\ANXA1, Hsap\ANXA8, Hsap\ANXA8L1, Hsap\ANXA10, Hsap\ANXA5" "lethal,viable" FBgn0001382 l(1)2Bn lethal (1) 2Bn http://flybase.org/reports/FBgn0001382 - gene - - - l(1)2Bn - - 27-Aug-18 DroID_v2018_08 - - - - - - "cell lethal,germline clone,lethal - all die before end of larval stage,recessive,some die during larval stage,lethal" FBgn0031837 DIP-iota Dpr-interacting protein iota http://flybase.org/reports/FBgn0031837 protein_coding_gene - synapse organization ; GO:0050808 | inferred from expression pattern integral component of plasma membrane ; GO:0005887 | inferred from sequence model "CT31597, CG11320, 11320, DIP-iota" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set" CG11320 27-Aug-18 DroID_v2018_08 "Drer\vsig8a, Drer\kirrel3a, Drer\lrit3a, Drer\esama, Drer\zgc:110372, Drer\lrit1a, Drer\cxadr, Drer\zgc:153073, Drer\sdk1b, Drer\gpa33, Drer\pigrl4.2, Drer\cxcr3.1, Drer\igsf11, Drer\jam3a, Drer\ush2a, Drer\kirrelb, Drer\vsig8b, Drer\jam3b, Drer\kirrela, Drer\lsamp, Drer\esamb, Drer\jam2a, Drer\LOC100151468, Drer\si:dkey-250k15.10, Drer\ncam1b, Drer\f11r.1, Drer\f11r.2, Drer\mxra8b, Drer\paplna, Drer\lrit1b, Drer\si:ch1073-459j12.1, Drer\LOC565947, Drer\dscama, Drer\si:dkey-65b12.12, Drer\si:zfos-1011f11.1, Drer\kirrel3b, Drer\sdk1a, Drer\igsf9bb, Drer\si:ch211-215e19.3, Drer\igsf9a, Drer\itgb4, Drer\negr1, Drer\mxra8a, Drer\opcml, Drer\kirrel3l, Drer\jam2b, Drer\si:ch211-9d9.7, Drer\ntm, Drer\lrit3b" - "Cele\rig-5, Cele\igcm-1, Cele\zig-5" "Xtro\lsamp, Xtro\pecam1, Xtro\papln, Xtro\fcrl3, Xtro\negr1, Xtro\kirrel2, Xtro\ntm, Xtro\igsf9b, Xtro\lrit3, Xtro\LOC100486104" "Mmus\Gpa33, Mmus\Negr1, Mmus\Lrit1, Mmus\Hepacam2, Mmus\Ptprq, Mmus\Papln, Mmus\Vsig1, Mmus\Jam3, Mmus\Fcer1a, Mmus\Vsig8, Mmus\Fcgr4, Mmus\Lrit3, Mmus\Esam, Mmus\Fcgr1, Mmus\Lsamp, Mmus\Pira11, Mmus\Ntm, Mmus\Igsf11, Mmus\Fcgr3, Mmus\Vsig2, Mmus\Cxadr, Mmus\Kirrel, Mmus\Gm1123, Mmus\Kirrel2, Mmus\Igsf5, Mmus\Fcrla, Mmus\Sdk1, Mmus\Igsf9b, Mmus\Fcrlb, Mmus\Kirrel3, Mmus\Opcml, Mmus\Jam2, Mmus\Iglon5, Mmus\Mxra8, Mmus\Fcgr2b, Mmus\Vsir, Mmus\F11r, Mmus\Clmp" "Hsap\IGLON5, Hsap\FCRL4, Hsap\VSIG1, Hsap\MXRA8, Hsap\IGSF5, Hsap\LRIT1, Hsap\FCGR3B, Hsap\FCGR1B, Hsap\KIRREL2, Hsap\LSAMP, Hsap\GPA33, Hsap\FCGR2B, Hsap\NTM, Hsap\SDK1, Hsap\KIRREL, Hsap\VSIG8, Hsap\JAM3, Hsap\PAPLN, Hsap\FCER1A, Hsap\ESAM, Hsap\LOC107987462, Hsap\IGSF11, Hsap\CLMP, Hsap\USH2A, Hsap\PECAM1, Hsap\C1orf204, Hsap\LILRA4, Hsap\C10orf54, Hsap\IGSF9B, Hsap\JAM2, Hsap\FCRLB, Hsap\F11R, Hsap\FCGR2A, Hsap\OPCML, Hsap\FCRLA, Hsap\FCGR3A, Hsap\FCGR1A, Hsap\CXADR, Hsap\LRIT3, Hsap\VSIG2, Hsap\NEGR1, Hsap\KIRREL3, Hsap\LILRB5, Hsap\FCRL6" viable FBgn0027121 l(?)A135 lethal (?) A135 http://flybase.org/reports/FBgn0027121 - gene - - - l(?)A135 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0031295 CG4375 - http://flybase.org/reports/FBgn0031295 protein_coding_gene - - - "BcDNA:AT13819, CG4375" - CG4375 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0267481 asRNA:CR45831 - http://flybase.org/reports/FBgn0267481 non_protein_coding_gene - - - CR45831 - CR45831 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0014875 Pt8 Protein 8 http://flybase.org/reports/FBgn0014875 - gene - - - Pt8 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0053418 5SrRNA:CR33418 5SrRNA:CR33418 http://flybase.org/reports/FBgn0053418 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33418, 5SrRNA:CR33418" - CR33418 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0011863 tRNA:Gly-GCC-1-5 transfer RNA:Glycine-GCC 1-5 http://flybase.org/reports/FBgn0011863 "FBgn0003778, FBgn0051978, FBgn0060219" tRNA_gene GGC codon-amino acid adaptor activity ; GO:0033462 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033462 cytosol ; GO:0005829 | inferred by curator from GO:0033462 "BG:DS04641.4, AE002690.trna18-GlyGCC, tRNA:G:GCC:AE002690-f, CR31978, tRNA:gly3:35Bb, tRNA[Gly-GCC], chr2L.trna27-GlyGCC, tRNA-Gly-GCC-1-5, tRNA:Gly-GCC-1-5, tRNA:G3:35Bb, GGC" - CR31978 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065939 l(2)SH0117 lethal (2) SH0117 http://flybase.org/reports/FBgn0065939 gene - - - "l(2)SH0117, l(2)SH2 0117" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0019670 mor(1)9 mortality gene (1)9 http://flybase.org/reports/FBgn0019670 - gene - - - mor(1)9 - - 27-Aug-18 DroID_v2018_08 - - - - - - short lived FBgn0259287 EP-787 - http://flybase.org/reports/FBgn0259287 gene - - - EP-787 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible wing FBgn0040984 CG4440 - http://flybase.org/reports/FBgn0040984 protein_coding_gene - - - "BcDNA:RE16123, CG4440" - CG4440 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC28042 K -0.218650732 0.803158428 0.08515672 -0.358683665 0.631598165 -2.240635291 FBgn0004811 fs(2)ltoPP43 female sterile (2) ltoPP43 http://flybase.org/reports/FBgn0004811 "FBgn0026579, FBgn0032823" protein_coding_gene - regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype chorion-containing eggshell formation ; GO:0007304 | inferred from mutant phenotype - "CG10528, l(2)38Ac, LD12957, BEST:LD12957, fs(2)ltoPP43" IPR013883:Transcription factor Iwr1 CG10528 27-Aug-18 DroID_v2018_08 Drer\slc7a6os Scer\IWR1 Cele\W01G7.4 Xtro\slc7a6os Mmus\Slc7a6os Hsap\SLC7A6OS "viable,fertile,lethal,recessive,visible,wild-type,long lived,female sterile" "eye,trichogen cell,mesothoracic tergum" FBgn0267469 lncRNA:CR45819 - http://flybase.org/reports/FBgn0267469 non_protein_coding_gene - - - CR45819 - CR45819 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259925 p150 - http://flybase.org/reports/FBgn0259925 protein_coding_gene - - - p150 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0067659 sbg strindberg http://flybase.org/reports/FBgn0067659 gene molecular_function ; GO:0003674 | no biological data available pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available sbg - - 27-Aug-18 DroID_v2018_08 - - - - - - female sterile FBgn0267425 asRNA:CR45778 - http://flybase.org/reports/FBgn0267425 non_protein_coding_gene - - - "CR45778, Mgn99994" - CR45778 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0026384 Or59a Odorant receptor 59a http://flybase.org/reports/FBgn0026384 - protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 olfactory receptor activity ; GO:0004984 | non-traceable author statement olfactory receptor activity ; GO:0004984 | inferred from sequence or structural similarity with Or85e odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from mutant phenotype sensory perception of smell ; GO:0007608 | non-traceable author statement sensory perception of smell ; GO:0007608 | inferred from sequence or structural similarity with Or85e integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 integral component of membrane ; GO:0016021 | inferred from sequence model integral component of membrane ; GO:0016021 | non-traceable author statement dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a "59a, DOR46, CG9820, AN6, 59D.1, dor46, DOR59D.1, Or59D.1, Or46, Or59a" "IPR004117:Olfactory receptor, insect" CG9820 27-Aug-18 DroID_v2018_08 - - - - - - adult stage sensory neuron &&of antennal segment 3

smell perception defective FBgn0033942 Cpr51A Cuticular protein 51A http://flybase.org/reports/FBgn0033942 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model multicellular organism reproduction ; GO:0032504 | inferred from expression pattern chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular space ; GO:0005615 | inferred from direct assay extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr51A, CG10112" IPR000618:Insect cuticle protein CG10112 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0003511 Sry-beta Serendipity beta http://flybase.org/reports/FBgn0003511 - protein_coding_gene DNA binding ; GO:0003677 | inferred from direct assay - nucleus ; GO:0005634 | inferred from direct assay polytene chromosome interband ; GO:0005705 | inferred from direct assay "srybeta, sry beta, sry, Sry-beta, sryb, sry-b, Srybeta, sry-beta, CG7938, ser" IPR013087:Zinc finger C2H2-type CG7938 27-Aug-18 DroID_v2018_08 "Drer\znf1078, Drer\si:dkeyp-113d7.1, Drer\znf1136, Drer\znf1070, Drer\drl, Drer\si:dkey-261j4.5, Drer\si:dkey-261j4.4, Drer\si:dkey-253d23.8, Drer\LOC108183935, Drer\zgc:174646, Drer\zgc:113209, Drer\LOC100537687, Drer\znf1051, Drer\znf1041, Drer\zgc:171551, Drer\znf1069, Drer\zgc:173714, Drer\si:ch73-367f21.6, Drer\znf1007, Drer\si:dkey-237m9.1, Drer\si:dkey-261j4.3, Drer\LOC100151333, Drer\znf1059, Drer\im:7141269" Scer\ZAP1 "Cele\klu-1, Cele\Y37E11B.1, Cele\sdz-12" - "Mmus\Zfp930, Mmus\Zfp873, Mmus\Zfp7, Mmus\Gm6710, Mmus\Zfp712, Mmus\Zfp157, Mmus\Zfp182, Mmus\Zbtb41, Mmus\Zfp26, Mmus\Zfp266, Mmus\Zfp37, Mmus\Zkscan8, Mmus\Zfp846, Mmus\Zfp661, Mmus\Zfp2, Mmus\Zkscan7, Mmus\Zfp689" "Hsap\ZNF717, Hsap\ZFP37, Hsap\ZNF689, Hsap\ZNF121, Hsap\ZNF510, Hsap\ZNF470, Hsap\ZNF808, Hsap\ZNF577, Hsap\ZNF561, Hsap\ZNF658, Hsap\ZNF576, Hsap\ZNF506, Hsap\ZFP69B, Hsap\ZNF555, Hsap\ZNF582, Hsap\ZNF679, Hsap\ZNF599, Hsap\ZNF2, Hsap\ZNF449, Hsap\ZBTB41, Hsap\ZNF300, Hsap\ZFP28, Hsap\ZNF630, Hsap\ZNF420, Hsap\ZNF70, Hsap\ZNF30, Hsap\ZNF182, Hsap\ZFP2, Hsap\ZNF268, Hsap\ZKSCAN7, Hsap\GZF1" embryonic stage -- adult stage "partially lethal - majority die,some die during pupal stage" FBgn0264419 FCO-D - http://flybase.org/reports/FBgn0264419 gene - - - FCO-D - - 27-Aug-18 DroID_v2018_08 - - - - - - "follicle cell,somatic clone" FBgn0060347 l(3)S143206 lethal (3) S143206 http://flybase.org/reports/FBgn0060347 gene - - - "1432/06, l(3)S143206" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0065635 l(2)SH0770 lethal (2) SH0770 http://flybase.org/reports/FBgn0065635 gene - - - "l(2)SH0770, l(2)SH2 0770" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0267479 asRNA:CR45829 - http://flybase.org/reports/FBgn0267479 non_protein_coding_gene - - - CR45829 - CR45829 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0261556 CG42674 - http://flybase.org/reports/FBgn0261556 protein_coding_gene Rho guanyl-nucleotide exchange factor activity ; GO:0005089 | inferred from sequence or structural similarity with RhoGEF2 imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype positive regulation of Rho protein signal transduction ; GO:0035025 | inferred from sequence or structural similarity with RhoGEF2 cell adhesion ; GO:0007155 | inferred from mutant phenotype regulation of cell shape ; GO:0008360 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG7323, CG42674, CG13812, CG32223, CG42348, CG13811" "IPR011993:PH domain-like, IPR000219:Dbl homology (DH) domain" CG42674 27-Aug-18 DroID_v2018_08 "Drer\plekhg6, Drer\plekhg7, Drer\plekhg5a, Drer\plekhg5b" - Cele\rhgf-2 "Xtro\plekhg7, Xtro\plekhg5" "Mmus\Arhgef15, Mmus\Plekhg5, Mmus\Arhgef5, Mmus\Plekhg6, Mmus\Arhgef26" "Hsap\PLEKHG6, Hsap\PLEKHG5, Hsap\PLEKHG7" DRSC29701 K -0.325217914 0.709144588 -0.223212133 0.24194284 1.769260906 0.753322761 FBgn0085599 CG41284 - http://flybase.org/reports/FBgn0085599 protein_coding_gene - - - CG41284 "IPR004302:Cellulose/chitin-binding protein, N-terminal" CG41284 27-Aug-18 DroID_v2018_08 - - - - Mmus\Defb46 - FBgn0028279 l(1)G0419 lethal (1) G0419 http://flybase.org/reports/FBgn0028279 gene - - - l(1)G0419 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,melanotic mass phenotype,recessive" melanotic mass FBgn0065593 l(2)SH0896 lethal (2) SH0896 http://flybase.org/reports/FBgn0065593 gene - - - "l(2)SH0896, l(2)SH2 0896" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0038153 Ir87a Ionotropic receptor 87a http://flybase.org/reports/FBgn0038153 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "Ir87a, DmelIR87a, CG14376, IR87a" IPR001638:Solute-binding protein family 3/N-terminal domain of MltF CG14376 27-Aug-18 DroID_v2018_08 "Drer\LOC100537813, Drer\grid1b, Drer\grid1a" - Cele\glr-8 - "Mmus\Grik4, Mmus\Grid1" "Hsap\GRID1, Hsap\GRIK3" FBgn0054001 CG34001 - http://flybase.org/reports/FBgn0054001 protein_coding_gene molecular_function ; GO:0003674 | no biological data available mitotic sister chromatid cohesion ; GO:0007064 | inferred from biological aspect of ancestor with PANTHER:PTN002006636 Ctf18 RFC-like complex ; GO:0031390 | inferred from biological aspect of ancestor with PANTHER:PTN002006636 microtubule associated complex ; GO:0005875 | inferred from direct assay "BP1041, CG34001" IPR018607:Chromosome transmission fidelity protein 8 CG34001 27-Aug-18 DroID_v2018_08 Drer\chtf8 Scer\CTF8 Cele\T22C1.4 Xtro\chtf8 Mmus\Chtf8 Hsap\CHTF8 FBgn0270924 zf30C zinc finger protein 30C http://flybase.org/reports/FBgn0270924 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 neuron development ; GO:0048666 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "CG3998, zf30C, l(2)k02506, clone 1.52, anon-EST:Liang-1.52, Zf30c, zf30c, Zn30C, C282, Zf30C" "IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG3998 27-Aug-18 DroID_v2018_08 Drer\si:dkey-208k4.2 "Scer\PZF1, Scer\AZF1" "Cele\mep-1, Cele\eor-1, Cele\pzf-1" - "Mmus\Zfp658, Mmus\Gm14124, Mmus\Zfp780b, Mmus\Zfp974, Mmus\Zfp62" "Hsap\ZBTB24, Hsap\ZNF780B" DRSC03641 I -0.618223147 -1.88228469 -1.255933617 1.201817881 -0.564299946 -0.416789385 FBgn0029681 CG15239 - http://flybase.org/reports/FBgn0029681 protein_coding_gene - - - CG15239 IPR031941:Domain of unknown function DUF4773 CG15239 27-Aug-18 DroID_v2018_08 - - Cele\C09D4.2 - - - DRSC17972 IE 1.669979836 3.148961189 2.900650034 0.31237846 -0.541279407 0.611735101 FBgn0053262 CG33262 - http://flybase.org/reports/FBgn0053262 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33262 IPR006631:Protein of unknown function DM4/12 CG33262 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC22893 E 0.304340266 0.131397568 0.453693319 -1.573998141 -0.393832035 0.219280077 FBgn0035674 CG13295 - http://flybase.org/reports/FBgn0035674 protein_coding_gene - - - CG13295 "IPR027986:T-cell activation inhibitor, mitochondrial, IPR027989:Domain of unknown function DUF4461, IPR028031:Domain of unknown function DUF4460" CG13295 27-Aug-18 DroID_v2018_08 Drer\tcaim - Cele\C35B8.3 Xtro\tcaim Mmus\Tcaim Hsap\TCAIM "viable,fertile" FBgn0016647 ER3-5 ER3-5 http://flybase.org/reports/FBgn0016647 - gene - - - ER3-5 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0266194 J29 - http://flybase.org/reports/FBgn0266194 gene - - - J29 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032149 CG4036 - http://flybase.org/reports/FBgn0032149 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR005123 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005123 demethylation ; GO:0070988 | inferred from electronic annotation with InterPro:IPR032857 larval lymph gland hemopoiesis ; GO:0035167 | inferred from mutant phenotype - CG4036 "IPR027450:Alpha-ketoglutarate-dependent dioxygenase AlkB-like, IPR032857:Alpha-ketoglutarate-dependent dioxygenase alkB homologue 4, IPR005123:Oxoglutarate/iron-dependent dioxygenase" CG4036 27-Aug-18 DroID_v2018_08 Drer\alkbh4 - Cele\F09F7.7 "Xtro\apex1, Xtro\alkbh4" "Mmus\Apex1, Mmus\Alkbh4" "Hsap\APEX1, Hsap\ALKBH4" viable FBgn0034295 CG10911 - http://flybase.org/reports/FBgn0034295 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon-WO0140519.211, CG10911" IPR007931:Protein of unknown function DUF725 CG10911 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0013229 E(var)181 E(var)181 http://flybase.org/reports/FBgn0013229 - gene - - - E(var)181 - - 27-Aug-18 DroID_v2018_08 - - - - - - "enhancer of variegation,dominant" FBgn0010180 tu(2)59h tu(2)59h http://flybase.org/reports/FBgn0010180 - gene - - - tu(2)59h - - 27-Aug-18 DroID_v2018_08 - - - - - - melanotic mass phenotype FBgn0002356 l(3)87Ec lethal (3) 87Ec http://flybase.org/reports/FBgn0002356 - gene - - - "c9a, C9a, l(3)C9a, l(3)c9a, l(3)87Ec" - - 27-Aug-18 DroID_v2018_08 - - - - - - "non-enhancer of variegation,non-suppressor of variegation,lethal,recessive" FBgn0035761 RhoGEF4 Rho guanine nucleotide exchange factor 4 http://flybase.org/reports/FBgn0035761 protein_coding_gene Rho guanyl-nucleotide exchange factor activity ; GO:0005089 | inferred from direct assay positive regulation of stress fiber assembly ; GO:0051496 | inferred from direct assay positive regulation of Rho protein signal transduction ; GO:0035025 | inferred from direct assay regulation of cell shape ; GO:0008360 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG8606, RhoGEF4, DRhoGEF4, RhoGEF" "IPR000219:Dbl homology (DH) domain, IPR001849:Pleckstrin homology domain, IPR011993:PH domain-like" CG8606 27-Aug-18 DroID_v2018_08 "Drer\net1, Drer\fgd1, Drer\arhgef39, Drer\fgd4a, Drer\LOC793364, Drer\fgd" "Scer\ROM2, Scer\FUS2, Scer\CDC24, Scer\ROM1" "Cele\exc-5, Cele\tag-52" "Xtro\fgd4, Xtro\spata13, Xtro\arhgef39" "Mmus\Arhgef38, Mmus\Arhgef4, Mmus\Fgd2, Mmus\Fgd4, Mmus\Fgd1, Mmus\Arhgef39, Mmus\Spata13, Mmus\Fgd3" "Hsap\FGD1, Hsap\FGD6, Hsap\ARHGEF39, Hsap\SPATA13, Hsap\FGD3, Hsap\ARHGEF38, Hsap\FGD4, Hsap\FGD2" "viable,fertile" FBgn0058265 CG40265 - http://flybase.org/reports/FBgn0058265 protein_coding_gene - - - CG40265 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040795 CG13038 - http://flybase.org/reports/FBgn0040795 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13038 - CG13038 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0024698 Cpsf160 Cleavage and polyadenylation specificity factor 160 http://flybase.org/reports/FBgn0024698 "FBgn0024812, FBgn0033941, FBgn0062164" protein_coding_gene mRNA binding ; GO:0003729 | inferred from biological aspect of ancestor with PANTHER:PTN000068525 myosin binding ; GO:0017022 | inferred from physical interaction with Myo10A mRNA 3'-UTR binding ; GO:0003730 | inferred from sequence or structural similarity with UniProtKB:Q10570 mRNA cleavage ; GO:0006379 | inferred from biological aspect of ancestor with PANTHER:PTN000068525 mRNA cleavage ; GO:0006379 | inferred from sequence or structural similarity with UniProtKB:Q10570 mRNA polyadenylation ; GO:0006378 | inferred from biological aspect of ancestor with PANTHER:PTN000068525 neurogenesis ; GO:0022008 | inferred from mutant phenotype mRNA polyadenylation ; GO:0006378 | inferred from sequence or structural similarity with UniProtKB:Q10570 mRNA cleavage and polyadenylation specificity factor complex ; GO:0005847 | inferred from sequence or structural similarity with UniProtKB:Q10570 mRNA cleavage and polyadenylation specificity factor complex ; GO:0005847 | inferred from biological aspect of ancestor with PANTHER:PTN000068526 "CG10110, Cpsf, dCPSF-160, CPSF, anon-WO0118547.217, Cpsf160, CPSF160, cpsf, CPSF-160" "IPR004871:Cleavage/polyadenylation specificity factor, A subunit, C-terminal, IPR015943:WD40/YVTN repeat-like-containing domain" CG10110 27-Aug-18 DroID_v2018_08 Drer\cpsf1 Scer\CFT1 Cele\cpsf-1 Xtro\cpsf1 Mmus\Cpsf1 Hsap\CPSF1 " embryonic stage--pupal stage , adult stage | male , adult stage | female " "lethal,recessive,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "hypostomal sclerite,embryonic/first instar larval cuticle,embryonic/larval neuroblast,ganglion mother cell" FBgn0024595 ziplock ziplock http://flybase.org/reports/FBgn0024595 - gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available ziplock - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0029989 CG15333 - http://flybase.org/reports/FBgn0029989 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG18293, CG15333" IPR006610:Domain of unknown function DM7 CG15333 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC18153 K 0.743692422 0.563382824 -0.14482529 0.387112552 0.732416646 2.723764001 FBgn0052181 CG32181 - http://flybase.org/reports/FBgn0052181 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT19257, CG32181" - CG32181 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0040668 CG17409 - http://flybase.org/reports/FBgn0040668 protein_coding_gene - - - CG17409 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004770 l(3)89Ei lethal (3) 89Ei http://flybase.org/reports/FBgn0004770 - gene - - - l(3)89Ei - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0020248 stet stem cell tumor http://flybase.org/reports/FBgn0020248 "FBgn0035221, FBgn0035223, FBgn0041725, FBgn0053166" protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN000532910 "protein processing ; GO:0016485 | inferred from biological aspect of ancestor with PANTHER:PTN000532910 male germ-line stem cell population maintenance ; GO:0036098 | inferred from genetic interaction with UniProtKB:A1YK24,UniProtKB:B8A421,UniProtKB:Q9VCH5" integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN001117493 "CG12083, Rho2, Brho, Rho-2, brho, rho-2, CG12504, CG33166, stet, B-Rho, rho2" "IPR002610:Peptidase S54, rhomboid, IPR011992:EF-hand domain pair, IPR017213:Peptidase S54, rhomboid, metazoan, IPR002048:EF-hand domain, IPR022764:Peptidase S54, rhomboid domain" CG33166 27-Aug-18 DroID_v2018_08 "Drer\rhbdl3, Drer\rhbdl2, Drer\rhbdl1" - "Cele\rom-1, Cele\rom-2" "Xtro\LOC101732375, Xtro\rhbdl2" "Mmus\Rhbdl1, Mmus\Rhbdl2, Mmus\Rhbdl3" "Hsap\RHBDL3, Hsap\RHBDL1, Hsap\RHBDL2" "viable,female sterile,recessive,fertile,male sterile" "testis,germline clone,germarium,spectrosome | supernumerary,spectrosome | germline clone | supernumerary,male germline stem cell,male germline cell,hub cell,cyst cell,female germline stem cell,egg chamber,ovariole,ovarian sheath cell,wing vein,ectopic,chorion,dorsal appendage,wing" DRSC08283 IE -0.839401677 1.538255786 1.685114917 -0.897983874 -0.044453521 -0.212339295 FBgn0010042 GstD6 Glutathione S transferase D6 http://flybase.org/reports/FBgn0010042 FBgn0038025 protein_coding_gene glutathione transferase activity ; GO:0004364 | inferred from direct assay glutathione metabolic process ; GO:0006749 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with RGD:70952 "DmGSTD6, DmGST25, Gst, GST, gstD25, GstD25, CG4423, GstD6, GSTD6, DmGstd6, gstd6" "IPR004045:Glutathione S-transferase, N-terminal, IPR004046:Glutathione S-transferase, C-terminal, IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold" CG4423 27-Aug-18 DroID_v2018_08 "Drer\gstr, Drer\gstt1b, Drer\gstt2, Drer\gstt1a, Drer\vars, Drer\mars, Drer\eef1e1, Drer\eef1g" "Scer\GTT1, Scer\GTT2, Scer\TEF4, Scer\YGR201C, Scer\CAM1, Scer\URE2" "Cele\gst-35, Cele\gst-34" "Xtro\gstt1, Xtro\eef1g, Xtro\eef1e1" "Mmus\Gstt4, Mmus\Vars, Mmus\Mars, Mmus\Eef1g, Mmus\Gstt2, Mmus\Gstt1, Mmus\Gstt3, Mmus\Eef1e1" "Hsap\GSTT1, Hsap\MARS, Hsap\GSTT2, Hsap\EEF1E1, Hsap\GSTT2B, Hsap\EEF1G, Hsap\VARS" adult stage viable FBgn0262610 CG43136 - http://flybase.org/reports/FBgn0262610 protein_coding_gene - - - "CG43136, chrX_5747778_5748511.0" IPR032145:Protein of unknown function DUF4818 CG43136 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032144 CG17633 - http://flybase.org/reports/FBgn0032144 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000834 metallocarboxypeptidase activity ; GO:0004181 | inferred from sequence or structural similarity with HGNC:2297 metallocarboxypeptidase activity ; GO:0004181 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000834, InterPro:IPR003146 neurogenesis ; GO:0022008 | inferred from mutant phenotype" extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 extracellular space ; GO:0005615 | inferred from sequence or structural similarity with UniProtKB:P15085 CG17633 "IPR000834:Peptidase M14, carboxypeptidase A, IPR009020:Protease propeptides/proteinase inhibitor I9, IPR034223:Insect gut carboxypeptidase-like, carboxypeptidase domain, IPR003146:Carboxypeptidase, activation peptide" CG17633 27-Aug-18 DroID_v2018_08 "Drer\cpo, Drer\cpa6, Drer\cpa1, Drer\cpa2, Drer\cpa4, Drer\cpb1, Drer\cpa5, Drer\cpb2" Scer\ECM14 "Cele\T06A4.1, Cele\T06A4.3, Cele\Y18H1A.9, Cele\Y47G6A.19, Cele\ZC434.9, Cele\W01A8.6, Cele\Y59C2A.1, Cele\suro-1, Cele\F02D8.4" "Xtro\cpo, Xtro\cpa1, Xtro\LOC100487462, Xtro\cpb1, Xtro\cpa3, Xtro\cpb2" "Mmus\Cpa5, Mmus\Cpb1, Mmus\Cpa1, Mmus\Cpa4, Mmus\Cpb2, Mmus\Cpa6, Mmus\Cpa3, Mmus\Cpa2" "Hsap\CPB1, Hsap\CPB2, Hsap\CPA5, Hsap\CPA4, Hsap\CPO, Hsap\CPA1, Hsap\CPA2, Hsap\CPA3, Hsap\CPA6" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0029857 wuho wuho http://flybase.org/reports/FBgn0029857 protein_coding_gene tRNA (guanine-N7-)-methyltransferase activity ; GO:0008176 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000418221 RNA (guanine-N7)-methylation ; GO:0036265 | inferred from electronic annotation with InterPro:IPR028884 spermatogenesis ; GO:0007283 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype female germ cell nucleus ; GO:0001674 | inferred from direct assay cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000418221 tRNA methyltransferase complex ; GO:0043527 | inferred from biological aspect of ancestor with PANTHER:PTN000418221 male germ cell nucleus ; GO:0001673 | inferred from direct assay "wuho, CG15897, wh" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR028884:tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit, Trm82" CG15897 27-Aug-18 DroID_v2018_08 Drer\wdr4 Scer\TRM82 Cele\Y102E9.2 - Mmus\Wdr4 Hsap\WDR4 "male sterile,female semi-sterile,viable" "ovariole,egg chamber,spermatozoon,mitochondrion & testis,spermatid cyst" FBgn0261920 EndoA::Hsap\TRIP10 - http://flybase.org/reports/FBgn0261920 engineered_fusion_gene - - - "endoA::Hsap\TRIP10, EndoA::Hsap\TRIP10" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266410 CG45050 - http://flybase.org/reports/FBgn0266410 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000058, InterPro:IPR002653 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR002653 molecular_function ; GO:0003674 | no biological data available" biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43674, CG45050, CG33936, anon-EST:fe1B11, anon-EST:fe2G11, drn, CG33188, BcDNA:RE70963, CG33937, CG33187, CG16750, CG16751, CG3393, anon-85Da, CG30492" "IPR000058:Zinc finger, AN1-type, IPR002653:Zinc finger, A20-type" CG45050 27-Aug-18 DroID_v2018_08 "Drer\zgc:77486, Drer\rabgef1, Drer\zfand4, Drer\rabgef1l, Drer\zfand6, Drer\zfand3, Drer\zfand5b, Drer\zfand5a" - "Cele\F22D6.2, Cele\F56F3.4" "Xtro\rabgef1, Xtro\zfand5, Xtro\zfand4, Xtro\zfand6, Xtro\zfand3" "Mmus\Zfand6, Mmus\Zfand5, Mmus\Zfand3, Mmus\Rabgef1, Mmus\Zfand4" "Hsap\ZFAND3, Hsap\RABGEF1, Hsap\ZFAND4, Hsap\ZFAND6, Hsap\ZFAND5" FBgn0050383 CG30383 - http://flybase.org/reports/FBgn0050383 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available CG30383 - CG30383 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" FBgn0265612 lncRNA:CR44430 - http://flybase.org/reports/FBgn0265612 non_protein_coding_gene - - - CR44430 - CR44430 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265857 lncRNA:CR44646 - http://flybase.org/reports/FBgn0265857 non_protein_coding_gene - - - CR44646 - CR44646 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000599 E(var)26A Enhancer of variegation 26A http://flybase.org/reports/FBgn0000599 - gene - - - "E-var(2)1, E(var)162, E(var)26A" - - 27-Aug-18 DroID_v2018_08 - - - - - - "enhancer of variegation,dominant" FBgn0014218 l(2)31Da lethal (2) 31Da http://flybase.org/reports/FBgn0014218 - gene - - - l(2)31Da - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0036908 TORIP Torsin interacting protein http://flybase.org/reports/FBgn0036908 protein_coding_gene - - - "CG14103, dLAP1, TORIP, LAP1" - CG14103 27-Aug-18 DroID_v2018_08 Drer\si:dkeyp-82a1.6 - - - "Mmus\Tor1aip2, Mmus\Tor1aip1" "Hsap\TOR1AIP1, Hsap\TOR1AIP2" "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0260286 GSd066 - http://flybase.org/reports/FBgn0260286 gene - - - GSd066 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0259656 B1523 - http://flybase.org/reports/FBgn0259656 gene - - - B1523 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0030801 Rcp Receptor component protein http://flybase.org/reports/FBgn0030801 protein_coding_gene nucleotide binding ; GO:0000166 | inferred from electronic annotation with InterPro:IPR010997 RNA polymerase III activity ; GO:0001056 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000399700 positive regulation of G-protein coupled receptor protein signaling pathway ; GO:0045745 | inferred from direct assay transcription initiation from RNA polymerase III promoter ; GO:0006384 | inferred from biological aspect of ancestor with PANTHER:PTN000399700 neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype DNA-directed RNA polymerase III complex ; GO:0005666 | inferred from biological aspect of ancestor with PANTHER:PTN000399700 "CG4875, Rcp, dRCP" "IPR006590:RNA polymerase II, Rpb4, core, IPR010997:HRDC-like, IPR005574:RNA polymerase II, Rpb4" CG4875 27-Aug-18 DroID_v2018_08 Drer\crcp Scer\RPC17 Cele\M106.7 Xtro\crcp "Mmus\Polr2d, Mmus\Crcp" "Hsap\POLR2D, Hsap\CRCP, Hsap\ASL" "visible,partially lethal - majority die,some die during pupal stage,lethal - all die before end of pupal stage" mesothoracic tergum FBgn0037842 CG6567 - http://flybase.org/reports/FBgn0037842 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from biological aspect of ancestor with PANTHER:PTN001639375 palmitoyl-(protein) hydrolase activity ; GO:0008474 | inferred from biological aspect of ancestor with PANTHER:PTN001639375 protein depalmitoylation ; GO:0002084 | inferred from biological aspect of ancestor with PANTHER:PTN001639375 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001639375 CG6567 "IPR003140:Phospholipase/carboxylesterase/thioesterase, IPR029058:Alpha/Beta hydrolase fold" CG6567 27-Aug-18 DroID_v2018_08 "Drer\lyplal1, Drer\lypla2" Scer\YLR118C Cele\F01D5.8 "Xtro\lyplal1, Xtro\lypla1, Xtro\lypla2" "Mmus\Lypla1, Mmus\Lyplal1, Mmus\Lypla2" "Hsap\LYPLAL1, Hsap\LYPLA2, Hsap\LYPLA1" "viable,fertile" FBgn0060631 l(3)S085505 lethal (3) S085505 http://flybase.org/reports/FBgn0060631 gene - - - "0855/05, l(3)S085505" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0001658 l(1)ds12 lethal (1) discs small 12 http://flybase.org/reports/FBgn0001658 - gene - - - "l(1)1-45, l(1)ds12" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" "imaginal disc,ring gland" FBgn0065707 l(2)SH0610 lethal (2) SH0610 http://flybase.org/reports/FBgn0065707 gene - - - "l(2)SH0610, l(2)SH2 0610" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0039667 CG2010 - http://flybase.org/reports/FBgn0039667 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model "CG2010, FBXL3" "IPR001810:F-box domain, IPR032675:Leucine-rich repeat domain, L domain-like" CG2010 27-Aug-18 DroID_v2018_08 Drer\si:ch211-214j8.12 - Cele\T28B4.1 - - - FBgn0031635 tank tank http://flybase.org/reports/FBgn0031635 protein_coding_gene - macroautophagy ; GO:0016236 | inferred from biological aspect of ancestor with PANTHER:PTN000483471 apoptotic process ; GO:0006915 | inferred from biological aspect of ancestor with PANTHER:PTN000483472 positive regulation of response to ethanol ; GO:1901418 | inferred from mutant phenotype endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000483471 "CG15626, tank" IPR009890:Etoposide-induced 2.4 CG15626 27-Aug-18 DroID_v2018_08 Drer\ei24 - Cele\epg-4 Xtro\ei24 Mmus\Ei24 Hsap\EI24 "chemical resistant,partially lethal - majority die,some die during pupal stage,lethal" FBgn0013257 E(var)3118 E(var)3118 http://flybase.org/reports/FBgn0013257 - gene - - - E(var)3118 - - 27-Aug-18 DroID_v2018_08 - - - - - - "enhancer of variegation,dominant" FBgn0024866 l(3)04679 lethal (3) 04679 http://flybase.org/reports/FBgn0024866 - gene - - - "4679, l(3)04679" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0011229 pto pistachio http://flybase.org/reports/FBgn0011229 - gene molecular_function ; GO:0003674 | no biological data available spermatid development ; GO:0007286 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available pto - - 27-Aug-18 DroID_v2018_08 - - - - - - male semi-sterile FBgn0060336 l(3)S144607a lethal (3) S144607a http://flybase.org/reports/FBgn0060336 gene - - - "1446/07, l(3)S144607a" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0040950 Muc26B Mucin 26B http://flybase.org/reports/FBgn0040950 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 extracellular matrix structural constituent ; GO:0005201 | inferred from sequence model chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 extracellular matrix ; GO:0031012 | inferred from sequence model "BcDNA:RE30702, Muc26B, CG13990" IPR002557:Chitin binding domain CG13990 27-Aug-18 DroID_v2018_08 - - Cele\Y5H2A.4 - - Hsap\KRTAP10-4 viable DRSC02322 E -0.818958477 0.202858201 1.850548973 0.333261046 0.470494197 -0.84474961 FBgn0005353 su(B)2 suppressor of Bar on 2 http://flybase.org/reports/FBgn0005353 - gene - - - su(B)2 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0028358 l(1)G0151 lethal (1) G0151 http://flybase.org/reports/FBgn0028358 gene - - - l(1)G0151 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" chaeta FBgn0002889 mus203 mutagen-sensitive 203 http://flybase.org/reports/FBgn0002889 - gene - - - mus203 - - 27-Aug-18 DroID_v2018_08 - - - - - - "chemical sensitive,recessive,radiation sensitive" FBgn0011160 l(1)Q238 lethal (1) Q238 http://flybase.org/reports/FBgn0011160 FBgn0010210 gene - - - l(1)Q238 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0265659 lncRNA:CR44466 - http://flybase.org/reports/FBgn0265659 non_protein_coding_gene - - - "lincRNA.328, CR44466" - CR44466 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0052785 tRNA:Gln-CTG-2-1 transfer RNA:Glutamine-CTG 2-1 http://flybase.org/reports/FBgn0052785 tRNA_gene CAG codon-amino acid adaptor activity ; GO:0033428 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033428 cytosol ; GO:0005829 | inferred by curator from GO:0033428 "AE002566.trna1-GlnCTG, tRNA:Q:CTG:AE002566, CR32785, chrX.trna1-GlnCTG, tRNA:Gln-CTG-2-1, tRNA:CR32785, tRNA-Gln-CTG-2-1, CAG" - CR32785 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033204 CG2065 - http://flybase.org/reports/FBgn0033204 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN000673029 - - CG2065 "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain" CG2065 27-Aug-18 DroID_v2018_08 "Drer\cbr1, Drer\si:ch211-107o10.3, Drer\rdh12l, Drer\dhrs13l1, Drer\dhrsx, Drer\si:ch211-165b10.3, Drer\si:dkey-23o4.6, Drer\ascc1, Drer\si:dkey-94e7.2, Drer\si:dkey-174n20.1, Drer\rdh14b, Drer\zgc:112332, Drer\flj13639, Drer\zgc:153441, Drer\dhrs13a.2, Drer\dhrs13a.3, Drer\dhrs13a.1, Drer\si:dkey-73n8.3, Drer\zgc:64106, Drer\rdh12, Drer\rdh14a, Drer\dhrs12, Drer\cbr1l" "Scer\ENV9, Scer\GPI11, Scer\YNL181W, Scer\YKL107W" "Cele\E04F6.15, Cele\DC2.5, Cele\K10H10.6, Cele\C27D8.4, Cele\dhs-22" "Xtro\rdh11, Xtro\ascc1, Xtro\dhrsx, Xtro\dhrs12, Xtro\rdh14, Xtro\dhrs13, Xtro\rdh13" "Mmus\Cbr1, Mmus\1700003E16Rik, Mmus\Ascc1, Mmus\Wwox, Mmus\Rdh11, Mmus\Dhrs13, Mmus\Rdh14, Mmus\Dhrsx, Mmus\Rdh13, Mmus\Rdh12, Mmus\Cbr3" "Hsap\RDH14, Hsap\DHRS13, Hsap\CBR3, Hsap\OSTC, Hsap\RDH11, Hsap\DHRS12, Hsap\CBR1, Hsap\C2orf81, Hsap\DHRSX, Hsap\RDH12, Hsap\RDH13" viable DRSC21328 K 0.274157004 0.931060458 -0.21244034 0.435516919 1.524758674 -1.117257957 FBgn0260107 2L2806 - http://flybase.org/reports/FBgn0260107 gene - "terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - 2L2806 - - 27-Aug-18 DroID_v2018_08 - - - - - - "terminal tracheal cell,somatic clone,embryonic/larval tracheal system" FBgn0265105 asRNA:CR44207 - http://flybase.org/reports/FBgn0265105 non_protein_coding_gene - - - CR44207 - CR44207 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002187 l(3)62Da lethal (3) 62Da http://flybase.org/reports/FBgn0002187 - gene - - - "dre10, l(3)Da, l(3)dre10, l(3)62Da" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0029172 Fad2 Fad2 http://flybase.org/reports/FBgn0029172 protein_coding_gene "oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water ; GO:0016717 | inferred from electronic annotation with InterPro:IPR015876" oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR015876 lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR005804 mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype courtship behavior ; GO:0007619 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype pheromone metabolic process ; GO:0042810 | inferred from mutant phenotype - "fad2, CG7923, fad, Fad2, desatF, desatF-alpha" "IPR001522:Fatty acid desaturase type 1, conserved site, IPR005804:Fatty acid desaturase domain, IPR015876:Acyl-CoA desaturase" CG7923 27-Aug-18 DroID_v2018_08 "Drer\scdb, Drer\scd" Scer\OLE1 "Cele\fat-5, Cele\fat-7, Cele\fat-6" Xtro\scd "Mmus\Scd2, Mmus\Scd4, Mmus\Scd1, Mmus\Scd3" "Hsap\SCD5, Hsap\SCD" "viable,visible,courtship behavior defective,mating defective" "trichogen cell,supernumerary,tormogen cell" DRSC11165 EK -0.152125597 -1.494320768 0.558777411 -2.763099657 -3.609312831 -2.579902426 FBgn0043550 Tsp68C Tetraspanin 68C http://flybase.org/reports/FBgn0043550 protein_coding_gene molecular_function ; GO:0003674 | no biological data available hemopoiesis ; GO:0030097 | inferred from genetic interaction with ytr lateral inhibition ; GO:0046331 | inferred from mutant phenotype cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 trans-Golgi network ; GO:0005802 | inferred from direct assay perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "Dm.Tsp68C, CG32136, Tsp68C, Tsp68c" "IPR018499:Tetraspanin/Peripherin, IPR008952:Tetraspanin, EC2 domain" CG32136 27-Aug-18 DroID_v2018_08 - - - Xtro\cd151 - Hsap\TSPAN11 "viable,fertile,visible" "chaeta,supernumerary,trichogen cell,tormogen cell,lamellocyte,embryonic/larval hemocyte" FBgn0031116 CG1695 - http://flybase.org/reports/FBgn0031116 protein_coding_gene Rab GTPase binding ; GO:0017137 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 GTPase activator activity ; GO:0005096 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with Evi5 intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 regulation of GTPase activity ; GO:0043087 | inferred from sequence or structural similarity with Evi5 activation of GTPase activity ; GO:0090630 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 regulation of vesicle fusion ; GO:0031338 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 intracellular ; GO:0005622 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 endomembrane system ; GO:0012505 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 CG1695 "IPR000195:Rab-GTPase-TBC domain, IPR004012:RUN domain" CG1695 27-Aug-18 DroID_v2018_08 "Drer\sgsm1b, Drer\sgsm2, Drer\sgsm1a" Scer\GYP7 Cele\tbc-8 "Xtro\sgsm2, Xtro\sgsm1" "Mmus\Sgsm1, Mmus\Sgsm2" "Hsap\SGSM2, Hsap\SGSM1" viable FBgn0023009 l(3)S101804 lethal (3) S101804 http://flybase.org/reports/FBgn0023009 - gene - - - "1018/04, l(3)S101804" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0034841 CG13541 - http://flybase.org/reports/FBgn0034841 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13541 - CG13541 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0036217 CG5906 - http://flybase.org/reports/FBgn0036217 protein_coding_gene - - integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR007248 "BcDNA:AT16953, CG5906" IPR007248:Mpv17/PMP22 CG5906 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-120k19.1, Drer\mpv17l2, Drer\pxmp2, Drer\mpv17" "Scer\YOR292C, Scer\SYM1" Cele\ZK470.1 "Xtro\mpv17l2, Xtro\pxmp2" "Mmus\Pxmp2, Mmus\Mpv17, Mmus\Mpv17l2, Mmus\Mpv17l" "Hsap\MPV17L, Hsap\PXMP2, Hsap\MPV17L2, Hsap\MPV17" viable FBgn0016730 Rst(2)chl Resistant to chlorpyrifos http://flybase.org/reports/FBgn0016730 - gene - - - Rst(2)chl - - 27-Aug-18 DroID_v2018_08 - - - - - - chemical resistant FBgn0016070 smg smaug http://flybase.org/reports/FBgn0016070 FBgn0010432 protein_coding_gene "RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR015327 translation repressor activity ; GO:0030371 | inferred from direct assay mRNA 3'-UTR binding ; GO:0003730 | traceable author statement mRNA binding ; GO:0003729 | traceable author statement translation repressor activity ; GO:0030371 | traceable author statement translation repressor activity, nucleic acid binding ; GO:0000900 | traceable author statement myosin binding ; GO:0017022 | inferred from physical interaction with Myo10A" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR015327 negative regulation of translation ; GO:0017148 | traceable author statement nuclear-transcribed mRNA poly(A) tail shortening ; GO:0000289 | inferred from mutant phenotype establishment of RNA localization ; GO:0051236 | inferred from mutant phenotype positive regulation of nuclear-transcribed mRNA poly(A) tail shortening ; GO:0060213 | inferred from mutant phenotype regulation of mRNA stability ; GO:0043488 | inferred from mutant phenotype negative regulation of translation ; GO:0017148 | inferred from direct assay" cytoplasmic mRNA processing body ; GO:0000932 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "SMG, CG5263, Smg, D69, anonD69, anon-D69, smg, Smaug, SmG, smaug" "IPR001660:Sterile alpha motif domain, IPR013761:Sterile alpha motif/pointed domain, IPR015327:Smaug, pseudo-HEAT analogous topology, IPR016024:Armadillo-type fold" CG5263 27-Aug-18 DroID_v2018_08 "Drer\samd4a, Drer\zcchc14" Scer\VTS1 Cele\ZC190.4 "Xtro\samd4b, Xtro\samd4a" "Mmus\Samd4b, Mmus\Samd4, Mmus\Zcchc14" "Hsap\SAMD4A, Hsap\SAMD4B, Hsap\ZCCHC14" "viable,fertile,wild-type,lethal - all die before end of embryonic stage,maternal effect,recessive,some die during embryonic stage,neuroanatomy defective" "syncytial blastoderm embryo,maternal effect,cycle 11 embryo,class IV dendritic arborizing neuron,ovary,class IV dendritic arborizing neuron | third instar larval stage" DRSC28033 K 0.573015392 0.231406075 0.31387203 -0.17976781 -2.340000303 0.592201943 FBgn0052190 NUCB1 NUCB1 http://flybase.org/reports/FBgn0052190 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR011330 carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR011330 defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype multicellular organism reproduction ; GO:0032504 | inferred from expression pattern Golgi apparatus ; GO:0005794 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay "CG5587, nucb1, CG32190, NUCB1, NucB1" "IPR018247:EF-Hand 1, calcium-binding site, IPR011992:EF-hand domain pair, IPR011330:Glycoside hydrolase/deacetylase, beta/alpha-barrel" CG32190 27-Aug-18 DroID_v2018_08 "Drer\nucb1, Drer\nucb2b, Drer\nucb2a" Scer\SSP120 Cele\nucb-1 "Xtro\nucb1, Xtro\nucb2" "Mmus\Nucb2, Mmus\Nucb1" "Hsap\GOLGA6L1, Hsap\NUCB1, Hsap\NUCB2" " embryonic stage | stage >=11 , embryonic stage | early " " embryonic/larval salivary gland

,

ubiquitous " embryonic stage embryonic/larval salivary gland

"viable,fertile" FBgn0264956 lncRNA:CR44125 - http://flybase.org/reports/FBgn0264956 non_protein_coding_gene - - - "lincRNA.250, CR44125" - CR44125 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065981 iab-5PRE iab-5 Polycomb group response element http://flybase.org/reports/FBgn0065981 regulatory_region - - - iab-5PRE - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0011956 tRNA:Arg-ACG-1-3 transfer RNA:Arginine-ACG 1-3 http://flybase.org/reports/FBgn0011956 "FBgn0003757, FBgn0011947, FBgn0050314, FBgn0060089" tRNA_gene CGU codon-amino acid adaptor activity ; GO:0033429 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033429 cytosol ; GO:0005829 | inferred by curator from GO:0033429 "tRNA Arg, tRNA[arg], tRNA[Arg][[2]], tRNA[Arg], AE002769.trna16-ArgACG, tRNA:R1, tRNA:arg1, tRNA:R:ACG:AE002769-d, tRNA:arg2:42Ab, CR30314, chr2R.trna8-ArgACG, tRNA-Arg-ACG-1-3, tRNA:Arg-ACG-1-3, tRNA:R2:42Ab, CGU" - CR30314 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262784 lncRNA:roX1::Dpse\roX1 - http://flybase.org/reports/FBgn0262784 engineered_fusion_gene - - - roX1::Dpse\roX1 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0062615 Mod(var)1259 Mod(var)1259 http://flybase.org/reports/FBgn0062615 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1259, Mod(var)1259" - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation,dominant" FBgn0069148 mcl(3)Z3808 mcl(3)Z3808 http://flybase.org/reports/FBgn0069148 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z3808 - - 27-Aug-18 DroID_v2018_08 - - - - - - male fertile FBgn0003245 r(alphaGPDH) regulator of alpha GPDH http://flybase.org/reports/FBgn0003245 - gene - - - "m[alpha-GPDH], r[3-55.4], m(GPDH), r(alphaGPDH)" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033702 CG8854 - http://flybase.org/reports/FBgn0033702 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG8854 - CG8854 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0029051 l(1)G0458 lethal (1) G0458 http://flybase.org/reports/FBgn0029051 gene - - - l(1)G0458 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0005488 l(1)ts1901 lethal (1) ts1901 http://flybase.org/reports/FBgn0005488 - gene - - - l(1)ts1901 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,heat sensitive" FBgn0014264 l(2)k04301a lethal (2) k04301a http://flybase.org/reports/FBgn0014264 - gene molecular_function ; GO:0003674 | no biological data available imaginal disc growth ; GO:0007446 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "l(2)k00202, l(2)43/1, l(2)k04301, l(2)k04301a" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,hyperplasia,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval brain,prothoracic leg disc,mesothoracic leg disc,metathoracic leg disc" FBgn0263583 lncRNA:CR43608 - http://flybase.org/reports/FBgn0263583 non_protein_coding_gene - - - CR43608 - CR43608 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031205 CG12474 - http://flybase.org/reports/FBgn0031205 protein_coding_gene - - - CG12474 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0019789 l(1)14 lethal (1) 14 http://flybase.org/reports/FBgn0019789 - gene - - - l(1)14 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0038753 CG4459 - http://flybase.org/reports/FBgn0038753 protein_coding_gene organic anion transmembrane transporter activity ; GO:0008514 | inferred from biological aspect of ancestor with PANTHER:PTN001936837 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000756324 CG4459 "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG4459 27-Aug-18 DroID_v2018_08 "Drer\oatx, Drer\sv2, Drer\slc22a13, Drer\slc22a17, Drer\slc22a7b.2, Drer\slc22a31, Drer\zmp:0000001102, Drer\slc22a7b.3, Drer\slc22a23, Drer\slc22a16, Drer\slc22a5, Drer\LOC100334012, Drer\LOC101884074, Drer\slc22a15, Drer\slc22a7b.1, Drer\slc22a6l, Drer\zgc:175176, Drer\slc22a21" "Scer\QDR2, Scer\QDR3, Scer\AQR1, Scer\FLR1, Scer\TPO1, Scer\YHK8, Scer\TPO2, Scer\TPO3, Scer\DTR1, Scer\QDR1" "Cele\F45E10.2, Cele\B0252.3, Cele\K05F1.6, Cele\oct-2, Cele\Y82E9BR.16" Xtro\slc22a6 "Mmus\Slc22a23, Mmus\Slc22a16, Mmus\Slc22a6, Mmus\Svop, Mmus\Slc22a14, Mmus\Slc22a17, Mmus\Slc22a29, Mmus\Slc22a19, Mmus\Slc22a26, Mmus\Slc22a2, Mmus\Slc22a8, Mmus\Slc22a27, Mmus\Slc22a28, Mmus\Slc22a4, Mmus\Slc22a7, Mmus\Slc22a30, Mmus\Slc22a22, Mmus\Slc22a15, Mmus\Sv2c, Mmus\Slc22a20" "Hsap\SV2B, Hsap\SV2C, Hsap\SLC22A12, Hsap\SLC22A11, Hsap\SLC22A10, Hsap\SLC22A24, Hsap\SLC22A2, Hsap\SLC22A15, Hsap\SLC22A25, Hsap\SVOP, Hsap\SLC22A8, Hsap\SLC22A17, Hsap\SLC22A1, Hsap\SLC22A31, Hsap\SLC22A9, Hsap\SLC22A23, Hsap\SLC22A6, Hsap\SLC22A7, Hsap\SLC22A16" viable FBgn0054010 Glyat - http://flybase.org/reports/FBgn0054010 protein_coding_gene N-acetyltransferase activity ; GO:0008080 | inferred from electronic annotation with InterPro:IPR000182 molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BP1022, CG34010" "IPR013653:FR47-like, IPR000182:GNAT domain, IPR016181:Acyl-CoA N-acyltransferase" CG34010 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-76k16.6, Drer\si:ch73-106k19.2, Drer\si:dkey-76k16.5" - Cele\ZK185.3 - "Mmus\Glyatl3, Mmus\Gm4952, Mmus\Glyat, Mmus\Keg1" "Hsap\GLYAT, Hsap\GLYATL1, Hsap\GLYATL3, Hsap\GLYATL2" FBgn0065322 l(2)SH1914 lethal (2) SH1914 http://flybase.org/reports/FBgn0065322 gene - - - "l(2)SH1914, l(2)SH2 1914" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0036254 CG5645 - http://flybase.org/reports/FBgn0036254 protein_coding_gene - "endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000447 | inferred from biological aspect of ancestor with PANTHER:PTN000375561" 90S preribosome ; GO:0030686 | inferred from biological aspect of ancestor with PANTHER:PTN000375561 nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000375561 CG5645 "IPR018034:KRR1 interacting protein 1, IPR024626:Kri1-like, C-terminal" CG5645 27-Aug-18 DroID_v2018_08 Drer\kri1 Scer\KRI1 Cele\F54C9.9 Xtro\kri1 Mmus\Kri1 Hsap\KRI1 "lethal,partially lethal - majority die,visible" trichogen cell DRSC10532 E -0.411041561 -0.150875183 -1.683113587 -0.077360627 -0.258991891 0.017162955 FBgn0265611 asRNA:CR44429 - http://flybase.org/reports/FBgn0265611 non_protein_coding_gene - - - CR44429 - CR44429 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0044085 E(rst)H122 E(rst)H122 http://flybase.org/reports/FBgn0044085 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "H122, E(rst)H122" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0021884 l(2)k13403 lethal (2) k13403 http://flybase.org/reports/FBgn0021884 - gene - - - l(2)k13403 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0023133 WppJ White prepupal locus J http://flybase.org/reports/FBgn0023133 - gene - - - "38, 23, 11, WppJ" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0013938 E(sina)3 Enhancer of seven in absentia 3 http://flybase.org/reports/FBgn0013938 - gene - - - E(sina)3 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" photoreceptor cell R7 FBgn0033548 CG7637 - http://flybase.org/reports/FBgn0033548 protein_coding_gene telomerase RNA binding ; GO:0070034 | inferred from biological aspect of ancestor with PANTHER:PTN000329686 box H/ACA snoRNA binding ; GO:0034513 | inferred from biological aspect of ancestor with PANTHER:PTN000329686 snRNA pseudouridine synthesis ; GO:0031120 | inferred from biological aspect of ancestor with PANTHER:PTN000329686 positive regulation of telomerase RNA localization to Cajal body ; GO:1904874 | inferred from biological aspect of ancestor with PANTHER:PTN000329686 telomere maintenance via telomerase ; GO:0007004 | inferred from biological aspect of ancestor with PANTHER:PTN000329686 rRNA pseudouridine synthesis ; GO:0031118 | inferred from biological aspect of ancestor with PANTHER:PTN000329686 cellular response to starvation ; GO:0009267 | inferred from expression pattern box H/ACA scaRNP complex ; GO:0072589 | inferred from biological aspect of ancestor with PANTHER:PTN000329686 box H/ACA telomerase RNP complex ; GO:0090661 | inferred from biological aspect of ancestor with PANTHER:PTN000329686 box H/ACA snoRNP complex ; GO:0031429 | inferred from biological aspect of ancestor with PANTHER:PTN000329686 CG7637 "IPR007264:H/ACA ribonucleoprotein complex, subunit Nop10" CG7637 27-Aug-18 DroID_v2018_08 Drer\nop10 Scer\NOP10 Cele\nola-3 Xtro\nop10 Mmus\Nop10 Hsap\NOP10 "viable,visible" "mesothoracic tergum,trichogen cell" FBgn0033158 CG12164 - http://flybase.org/reports/FBgn0033158 protein_coding_gene - - - CG12164 "IPR009078:Ferritin-like superfamily, IPR032134:Protein of unknown function DUF4816" CG12164 27-Aug-18 DroID_v2018_08 - Scer\DDR48 Cele\D1086.9 - Mmus\Sbsn - viable FBgn0015822 T-A7.1 T-A7.1 http://flybase.org/reports/FBgn0015822 - gene - - - T-A7.1 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0024639 l(2)k13217 lethal (2) k13217 http://flybase.org/reports/FBgn0024639 - gene - - - "132/17, l(2)k13217" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0039857 RpL6 Ribosomal protein L6 http://flybase.org/reports/FBgn0039857 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from direct assay structural constituent of ribosome ; GO:0003735 | traceable author statement "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR000915, InterPro:IPR005568 cytoplasmic translation ; GO:0002181 | traceable author statement centrosome duplication ; GO:0051298 | inferred from mutant phenotype ribosomal large subunit assembly ; GO:0000027 | inferred from biological aspect of ancestor with PANTHER:PTN000076315 cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 centrosome organization ; GO:0051297 | inferred from mutant phenotype" ribosome ; GO:0005840 | inferred from direct assay cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement cytosolic ribosome ; GO:0022626 | inferred from direct assay "CG11522, RpL6, Rp L6, RPL6, rpl6" "IPR000915:60S ribosomal protein L6E, IPR005568:Ribosomal protein L6, N-terminal, IPR008991:Translation protein SH3-like domain, IPR014722:Ribosomal protein L2 domain 2" CG11522 27-Aug-18 DroID_v2018_08 Drer\rpl6 "Scer\RPL6A, Scer\RPL6B" Cele\rpl-6 Xtro\rpl6 Mmus\Rpl6 Hsap\RPL6 DRSC14323 IEK 4.084981903 -1.009584704 2.967252844 -3.457939169 0.733726893 4.0728822 FBgn0005189 l(2)S45 lethal of Seto 45 http://flybase.org/reports/FBgn0005189 - gene - - - l(2)S45 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" leg FBgn0062684 EP1555 EP1555 http://flybase.org/reports/FBgn0062684 gene - - - "EP(X)1555, EP1555" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262279 mir-983-2 mir-983-2 stem loop http://flybase.org/reports/FBgn0262279 miRNA_gene - - - "mir-983-2, miR-983-2, 983-2, CR42986, miR-983" - CR42986 27-Aug-18 DroID_v2018_08 - - - - - - "visible,lethal" wing FBgn0032096 Or30a Odorant receptor 30a http://flybase.org/reports/FBgn0032096 protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 "30a, DOR56, 30A.1, CG13106, Or30a" "IPR004117:Olfactory receptor, insect" CG13106 27-Aug-18 DroID_v2018_08 - - - - - - "smell perception defective,viable" FBgn0033400 CG2063 - http://flybase.org/reports/FBgn0033400 protein_coding_gene - "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR012479 neurogenesis ; GO:0022008 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013" precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay CG2063 IPR012479:SAP30-binding protein CG2063 27-Aug-18 DroID_v2018_08 Drer\sap30bp - Cele\Y67D2.7 Xtro\sap30bp Mmus\Sap30bp Hsap\SAP30BP "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC06811 K 0.074324906 1.070768493 -0.041174307 0.753273232 -1.502907091 -1.19622964 FBgn0263998 Ack-like Activated Cdc42 kinase-like http://flybase.org/reports/FBgn0263998 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 protein tyrosine kinase activity ; GO:0004713 | inferred from sequence or structural similarity receptor binding ; GO:0005102 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 protein tyrosine kinase activity ; GO:0004713 | non-traceable author statement non-membrane spanning protein tyrosine kinase activity ; GO:0004715 | inferred from biological aspect of ancestor with PANTHER:PTN000700357" regulation of cell proliferation ; GO:0042127 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 cell differentiation ; GO:0030154 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 protein phosphorylation ; GO:0006468 | non-traceable author statement autophagic cell death ; GO:0048102 | inferred from expression pattern protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern cell migration ; GO:0016477 | inferred from biological aspect of ancestor with PANTHER:PTN001231165 transmembrane receptor protein tyrosine kinase signaling pathway ; GO:0007169 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 peptidyl-tyrosine autophosphorylation ; GO:0038083 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 innate immune response ; GO:0045087 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 extrinsic component of cytoplasmic side of plasma membrane ; GO:0031234 | inferred from biological aspect of ancestor with PANTHER:PTN000700357 "PR2, CG43741, CG3969, DPR2, PR2/ACK, DmHD-11, DRODPR2, dACK, Rp2, HD-11, CG33007, Ack-like" "IPR011511:Variant SH3 domain, IPR017441:Protein kinase, ATP binding site, IPR011009:Protein kinase-like domain, IPR001452:SH3 domain, IPR000719:Protein kinase domain, IPR000095:CRIB domain, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain, IPR008266:Tyrosine-protein kinase, active site, IPR020635:Tyrosine-protein kinase, catalytic domain" CG43741 27-Aug-18 DroID_v2018_08 "Drer\syk, Drer\zap70, Drer\LOC100148041, Drer\tnk2b" - "Cele\ark-1, Cele\kin-32" "Xtro\syk, Xtro\zap70, Xtro\tnk2" "Mmus\Tnk1, Mmus\Tnk2, Mmus\Zap70, Mmus\Syk" "Hsap\TNK2, Hsap\SYK, Hsap\ZAP70, Hsap\TNK1" FBgn0045841 betaTub56D::betaTub85D betaTub56D::betaTub85D http://flybase.org/reports/FBgn0045841 engineered_fusion_gene - - - betaTub56D::betaTub85D - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0061078 l(3)S014917b lethal (3) S014917b http://flybase.org/reports/FBgn0061078 gene - - - "0149/17, l(3)S014917b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0001456 l(1)7Dj lethal (1) 7Dj http://flybase.org/reports/FBgn0001456 - gene - - - l(1)7Dj - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0013689 mt:tRNA:Ala-TGC mitochondrial transfer RNA:Alanine-TGC http://flybase.org/reports/FBgn0013689 FBgn0002867 tRNA_gene - - - "CR34077, Dm mt tRNA[Ala], mtdbD00006302, mt:tRNA:Ala-TGC, mt:tRNA:A, tRNA[Ala]" - CR34077 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065099 snRNA:7SK small nuclear RNA 7SK http://flybase.org/reports/FBgn0065099 snRNA_gene - - - "snmRNA:331, CR33925, Dm-331, d7SK, snRNA:7SK, snmRNA:331-RA, 7SK snRNA, 7SK RNA, 7SK, chr3R:3300517..3300757" - CR33925 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037020 Pex14 Peroxin 14 http://flybase.org/reports/FBgn0037020 protein_coding_gene receptor binding ; GO:0005102 | inferred from biological aspect of ancestor with PANTHER:PTN000551635 "protein import into peroxisome matrix, docking ; GO:0016560 | inferred from biological aspect of ancestor with PANTHER:PTN000551635 protein targeting to peroxisome ; GO:0006625 | inferred from sequence or structural similarity with HGNC:8856,SGD:S000003121 peroxisome organization ; GO:0007031 | inferred from mutant phenotype" "peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:8856 peroxisomal membrane ; GO:0005778 | inferred from sequence or structural similarity with HGNC:8856,SGD:S000003121 peroxisomal importomer complex ; GO:1990429 | inferred from biological aspect of ancestor with PANTHER:PTN000551635 peroxisomal membrane ; GO:0005778 | inferred from biological aspect of ancestor with PANTHER:PTN000551635" "CG4289, Pex14, DmelPex14, PEX14" "IPR025655:Peroxisomal membrane protein 14, IPR006785:Peroxisome membrane anchor protein Pex14p, N-terminal" CG4289 27-Aug-18 DroID_v2018_08 Drer\pex14 Scer\PEX14 Cele\prx-14 Xtro\pex14 Mmus\Pex14 Hsap\PEX14 viable FBgn0036988 CG5262 - http://flybase.org/reports/FBgn0036988 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon-WO0118547.347, CG5262" "IPR013057:Amino acid transporter, transmembrane domain" CG5262 27-Aug-18 DroID_v2018_08 Drer\tmem104 - Cele\C03A3.2 Xtro\tmem104 Mmus\Tmem104 Hsap\TMEM104 viable FBgn0037235 CG1103 - http://flybase.org/reports/FBgn0037235 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG1103, anon-WO0118547.152" IPR026748:Clarin CG1103 27-Aug-18 DroID_v2018_08 "Drer\clrn1, Drer\clrn2, Drer\clrn3" - Cele\Y67D8C.22 - "Mmus\Clrn3, Mmus\Clrn1, Mmus\Clrn2" "Hsap\CLRN3, Hsap\CLRN1, Hsap\CLRN2" DRSC24616 K -2.193477536 0.118010086 FBgn0044381 anon-5.9 anon-5.9 http://flybase.org/reports/FBgn0044381 repeat_region - - - anon-5.9 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264462 lncRNA:CR43870 - http://flybase.org/reports/FBgn0264462 non_protein_coding_gene - - - CR43870 - CR43870 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264256 naz nazgul http://flybase.org/reports/FBgn0264256 protein_coding_gene - - cytoplasm ; GO:0005737 | inferred from direct assay "Naz, naz" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0062661 EP3223 EP3223 http://flybase.org/reports/FBgn0062661 gene - - - "EP(3)3223, EP3223" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0083259 E(smoDN)871 Enhancer of smoDN 871 http://flybase.org/reports/FBgn0083259 gene - - - E(smoDN)871 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0053364 5SrRNA:CR33364 5SrRNA:CR33364 http://flybase.org/reports/FBgn0053364 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33364, 5SrRNA:CR33364" - CR33364 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0285944 para Shudderer http://flybase.org/reports/FBgn0003402 - gene - - - "Shudderer, Shu" - - 27-Aug-18 DroID_v2018_08 - - - - - - "uncoordinated,gravitaxis defective" FBgn0286203 stw laccase 2 http://flybase.org/reports/FBgn0259247 protein_coding_gene "copper ion binding ; GO:0005507 | inferred from electronic annotation with InterPro:IPR002355, InterPro:IPR011706, InterPro:IPR011707 ferroxidase activity ; GO:0004322 | inferred from biological aspect of ancestor with PANTHER:PTN001709969 iron ion transmembrane transporter activity ; GO:0005381 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001709969" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001117, InterPro:IPR011706 chitin-based cuticle development ; GO:0040003 | inferred from mutant phenotype iron ion transport ; GO:0006826 | inferred from biological aspect of ancestor with PANTHER:PTN001709969 iron assimilation by reduction and transport ; GO:0033215 | inferred from biological aspect of ancestor with PANTHER:PTN001709969" high-affinity iron permease complex ; GO:0033573 | inferred from biological aspect of ancestor with PANTHER:PTN001709969 "laccase2, CG42345, CG10408, CG10398, CG30437, CG32838, MCO2" "IPR001117:Multicopper oxidase, type 1, IPR002355:Multicopper oxidase, copper-binding site, IPR008972:Cupredoxin, IPR011706:Multicopper oxidase, type 2, IPR011707:Multicopper oxidase, type 3, IPR033138:Multicopper oxidases, conserved site" CG42345 27-Aug-18 DroID_v2018_08 "Drer\hephl1b, Drer\cp" "Scer\GMC1, Scer\FET3, Scer\FET5" Cele\F21D5.3 Xtro\hephl1 "Mmus\Hephl1, Mmus\Cp, Mmus\Heph" "Hsap\HEPH, Hsap\CP, Hsap\HEPHL1" DRSC26018 K -0.480722888 0.331649162 0.434171433 0.428054987 2.307090213 0.508630512 FBgn0266158 lncRNA:CR44864 - http://flybase.org/reports/FBgn0266158 non_protein_coding_gene - - - CR44864 - CR44864 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0083300 E(smoDN)1823 Enhancer of smoDN 1823 http://flybase.org/reports/FBgn0083300 gene - - - E(smoDN)1823 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036819 Dysb Dysbindin http://flybase.org/reports/FBgn0036819 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Snapin inferred from physical interaction with Blos4 "regulation of synaptic plasticity ; GO:0048167 | inferred from mutant phenotype mating behavior, sex discrimination ; GO:0048047 | inferred from mutant phenotype regulation of synapse organization ; GO:0050807 | inferred from genetic interaction with Blos1 olfactory learning ; GO:0008355 | inferred from mutant phenotype long-term memory ; GO:0007616 | inferred from mutant phenotype eye pigment granule organization ; GO:0008057 | inferred from mutant phenotype short-term memory ; GO:0007614 | inferred from mutant phenotype positive regulation of synaptic transmission, glutamatergic ; GO:0051968 | inferred from mutant phenotype adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype negative regulation of dopamine metabolic process ; GO:0045963 | inferred from direct assay inferred from genetic interaction with e regulation of neuromuscular synaptic transmission ; GO:1900073 | inferred from mutant phenotype" neuromuscular junction of somatic muscle ; GO:0098527 | inferred from direct assay BLOC-1 complex ; GO:0031083 | inferred from sequence or structural similarity with HGNC:17328 synaptic vesicle ; GO:0008021 | inferred from direct assay "Dysb, dysb, CG6856, Ddysb, NP_649064" IPR007531:Dysbindin CG6856 27-Aug-18 DroID_v2018_08 "Drer\si:ch1073-174d20.1, Drer\dtnbp1a, Drer\dtnbp1b, Drer\si:ch211-253b8.5" - Cele\dsbn-1 "Xtro\dbndd1, Xtro\dtnbp1" "Mmus\Dbndd2, Mmus\Dtnbp1, Mmus\Dbndd1" "Hsap\DBNDD2, Hsap\DBNDD1, Hsap\DTNBP1" "neurophysiology defective,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage,courtship behavior defective,eye color defective,viable,visible,memory defective,recessive,locomotor behavior defective" "embryonic/larval neuromuscular junction | larval stage,trichogen cell,embryonic/larval neuromuscular junction" FBgn0053543 CG33543 - http://flybase.org/reports/FBgn0053543 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - - "CG15355, CG15354, CT35364, CT35363, CG33543, 33543" "IPR003598:Immunoglobulin subtype 2, IPR003961:Fibronectin type III, IPR013098:Immunoglobulin I-set, IPR013783:Immunoglobulin-like fold, IPR007110:Immunoglobulin-like domain, IPR003599:Immunoglobulin subtype, IPR013151:Immunoglobulin" CG33543 27-Aug-18 DroID_v2018_08 "Drer\opcml, Drer\ntm, Drer\zgc:110372, Drer\cep41" - - "Xtro\icam5, Xtro\negr1, Xtro\ntm, Xtro\lsamp" "Mmus\Cep41, Mmus\Opcml, Mmus\Lsamp, Mmus\Speg, Mmus\Iglon5, Mmus\Ntm" "Hsap\OPCML, Hsap\CEP41, Hsap\LSAMP, Hsap\NTM, Hsap\IGLON5" viable FBgn0039551 Or98a Odorant receptor 98a http://flybase.org/reports/FBgn0039551 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | inferred from direct assay detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a integral component of membrane ; GO:0016021 | inferred from direct assay "98a, CG5540, DOR110, 98B.1, Or98a, Or98A, DmOr98a" "IPR004117:Olfactory receptor, insect" CG5540 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0038268 CG3631 - http://flybase.org/reports/FBgn0038268 protein_coding_gene protein kinase activity ; GO:0004672 | inferred from sequence or structural similarity with fj protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with fj endoplasmic reticulum ; GO:0005783 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay CG3631 "IPR009581:FAM20, C-terminal, IPR024869:FAM20" CG3631 27-Aug-18 DroID_v2018_08 "Drer\fam20cb, Drer\fam20b, Drer\samd7, Drer\fam20a, Drer\fam20cl, Drer\fam20ca" - Cele\H03A11.1 "Xtro\samd7, Xtro\fam20a, Xtro\fam20c, Xtro\fam20b" "Mmus\Fam20c, Mmus\Fam20a, Mmus\Samd7, Mmus\Fam20b" "Hsap\FAM20B, Hsap\SAMD7, Hsap\FAM20A, Hsap\FAM20C" "viable,fertile" FBgn0053017 CG33017 - http://flybase.org/reports/FBgn0053017 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG15703, CG15702, CG33017" IPR006578:MADF domain CG33017 27-Aug-18 DroID_v2018_08 - - - - Mmus\Gpatch8 Hsap\GPATCH8 viable FBgn0003641 su(w[h]) suppressor of white-honey http://flybase.org/reports/FBgn0003641 - gene - - - su(w[h]) - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0028156 l(3)S042228 lethal (3) S042228 http://flybase.org/reports/FBgn0028156 gene - - - "0422/28, l(3)S042228" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0265177 CG44242 - http://flybase.org/reports/FBgn0265177 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG44242, CG8446" "IPR020373:Ribosomal protein S36, mitochondrial" CG44242 27-Aug-18 DroID_v2018_08 - Scer\AIM22 Cele\gip-2 - Mmus\Lipt1 Hsap\LIPT1 "viable,fertile" FBgn0005165 l(2)G559 lethal (2) G559 http://flybase.org/reports/FBgn0005165 - gene - - - l(2)G559 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0050211 tRNA:Trp-CCA-1-2 transfer RNA:Tryptophan-CCA 1-2 http://flybase.org/reports/FBgn0050211 tRNA_gene UGG codon-amino acid adaptor activity ; GO:0033416 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033416 cytosol ; GO:0005829 | inferred by curator from GO:0033416 "AE002787.trna1-TrpCCA, tRNA:W:CCA:AE002787-a, CR30146, CR30211, chr2R.trna59-TrpCCA, tRNA-Trp-CCA-1-2, tRNA:Trp-CCA-1-2, tRNA:CR30211, UGG" - CR30211 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266142 lncRNA:CR44848 - http://flybase.org/reports/FBgn0266142 non_protein_coding_gene - - - CR44848 - CR44848 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0025121 su(RpII140[Z36])S7 su(RpII140[Z36])S7 http://flybase.org/reports/FBgn0025121 - gene - - - "Z36[S7], su(RpII140[Z36])S7" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034324 CG18538 - http://flybase.org/reports/FBgn0034324 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG18538 IPR010512:Protein of unknown function DUF1091 CG18538 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0264874 asRNA:CR44065 - http://flybase.org/reports/FBgn0264874 non_protein_coding_gene - - - CR44065 - CR44065 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0016816 l(1)L19 lethal (1) L19 http://flybase.org/reports/FBgn0016816 - gene - - - "l(1)L19, L19" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0004149 l(2)57Ac lethal (2) 57Ac http://flybase.org/reports/FBgn0004149 - gene - - - l(2)57Ac - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0065891 l(2)SH0218 lethal (2) SH0218 http://flybase.org/reports/FBgn0065891 gene - - - "l(2)SH0218, l(2)SH2 0218" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0085289 CG34260 - http://flybase.org/reports/FBgn0085289 protein_coding_gene - - - CG34260 "IPR014756:Immunoglobulin E-set, IPR010512:Protein of unknown function DUF1091" CG34260 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0013540 l(2)ry51 lethal (2) ry51 http://flybase.org/reports/FBgn0013540 - gene - - - "l(2)51, l(2)ry51" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0029030 l(2)R99 lethal (2) R99 http://flybase.org/reports/FBgn0029030 gene - - - "R99, l(2)R99" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0260747 Chchd2 - http://flybase.org/reports/FBgn0260747 protein_coding_gene - mitochondrion organization ; GO:0007005 | inferred from biological aspect of ancestor with PANTHER:PTN000338319 nucleoplasm ; GO:0005654 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000338319 "BcDNA:RE73921, CG5010, anon-15Dd" - CG5010 27-Aug-18 DroID_v2018_08 "Drer\chchd2, Drer\chchd10" Scer\MIX17 Cele\har-1 "Xtro\gpat3, Xtro\dnajb4, Xtro\chchd10" "Mmus\Gm13202, Mmus\Chchd2, Mmus\Chchd10" "Hsap\CHCHD2, Hsap\CHCHD10" FBgn0264820 CR44028 - http://flybase.org/reports/FBgn0264820 pseudogene_attribute - - - CR44028 - CR44028 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0019970 Indf Indifferent http://flybase.org/reports/FBgn0019970 - gene - - - Indf - - 27-Aug-18 DroID_v2018_08 - - - - - - "smell perception defective,dominant,recessive,viable,semidominant" FBgn0036685 CG6664 - http://flybase.org/reports/FBgn0036685 protein_coding_gene molecular_function ; GO:0003674 | no biological data available establishment of meiotic spindle orientation ; GO:0051296 | inferred from sequence or structural similarity with WB:WBGene00002994 spindle pole ; GO:0000922 | inferred from sequence or structural similarity with WB:WBGene00002994 condensed chromosome ; GO:0000793 | inferred from sequence or structural similarity with WB:WBGene00002994 CG6664 IPR019152:Protein of unknown function DUF2046 CG6664 27-Aug-18 DroID_v2018_08 "Drer\ccdc6b, Drer\lrrc45, Drer\ccdc6a" - Cele\T09B9.4 "Xtro\ccdc157, Xtro\ccdc6" Mmus\Ccdc6 "Hsap\GOLGA6L10, Hsap\GOLGA8J, Hsap\GOLGA8N, Hsap\CCDC6, Hsap\GOLGA8A, Hsap\LOC100132202, Hsap\GOLGA8K, Hsap\GOLGA6L9, Hsap\GOLGA6L2, Hsap\GOLGA8O, Hsap\GOLGA8M, Hsap\GOLGA6L22, Hsap\GOLGA6L1, Hsap\GOLGA6L3, Hsap\GOLGA8B, Hsap\GOLGA8H, Hsap\LOC645202, Hsap\GOLGA6L4" viable FBgn0263954 BG01004 - http://flybase.org/reports/FBgn0263954 gene - - - BG01004 - - 27-Aug-18 DroID_v2018_08 - - - - - - "long lived,male limited,starvation stress response defective,temperature response defective" FBgn0014045 Su(tor)2-187-1 Su(tor)2-187-1 http://flybase.org/reports/FBgn0014045 - gene - - - Su(tor)2-187-1 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,maternal effect,recessive" FBgn0016644 ER3-2 ER3-2 http://flybase.org/reports/FBgn0016644 - gene - - - ER3-2 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0260117 2L1629 - http://flybase.org/reports/FBgn0260117 gene - - - 2L1629 - - 27-Aug-18 DroID_v2018_08 - - - - - - "terminal tracheal cell,somatic clone,embryonic/larval tracheal system" FBgn0265687 lncRNA:CR44494 - http://flybase.org/reports/FBgn0265687 non_protein_coding_gene - - - "lincRNA.112, CR44494" - CR44494 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0067331 2D5 2D5 http://flybase.org/reports/FBgn0067331 gene molecular_function ; GO:0003674 | no biological data available imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available 2D5 - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,somatic clone,viable" "wing vein,somatic clone" FBgn0052845 CG32845 - http://flybase.org/reports/FBgn0052845 protein_coding_gene isomerase activity ; GO:0016853 | inferred from electronic annotation with InterPro:IPR000297 - - CG32845 "IPR000297:Peptidyl-prolyl cis-trans isomerase, PpiC-type, IPR001202:WW domain, IPR023058:Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site" CG32845 27-Aug-18 DroID_v2018_08 Drer\pin1 Scer\ESS1 "Cele\Y40B1A.2, Cele\pinn-1" Xtro\pin1 "Mmus\Pin1rt1, Mmus\Pin1" Hsap\PIN1 FBgn0084326 Su(dpp)YE28 Su(dpp)YE28 http://flybase.org/reports/FBgn0084326 gene - - - Su(dpp)YE28 - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,female sterile" FBgn0022033 l(2)k08708 lethal (2) k08708 http://flybase.org/reports/FBgn0022033 - gene - - - l(2)k08708 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0267632 asRNA:CR45970 - http://flybase.org/reports/FBgn0267632 non_protein_coding_gene - - - CR45970 - CR45970 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0010272 Sry-rDM17 Sry-related DM17 http://flybase.org/reports/FBgn0010272 - gene DNA binding ; GO:0003677 | inferred from sequence or structural similarity - nucleus ; GO:0005634 | inferred from sequence or structural similarity "DM17, Sry-rDM17" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085769 CR40728 - http://flybase.org/reports/FBgn0085769 rRNA_gene - - - CR40728 - CR40728 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259315 C143 - http://flybase.org/reports/FBgn0259315 gene - - - C143 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing hair,wing vein,wing,chaeta" FBgn0034509 Obp57c Odorant-binding protein 57c http://flybase.org/reports/FBgn0034509 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush odorant binding ; GO:0005549 | inferred from sequence or structural similarity with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 transport ; GO:0006810 | non-traceable author statement sensory perception of smell ; GO:0007608 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 extracellular region ; GO:0005576 | inferred from sequence model extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 "CG13421, Obp57a, 57c, BcDNA:RH68952, Obp57c, DmelObp57c, obp57c" IPR006170:Pheromone/general odorant binding protein CG13421 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0040647 CG10987 - http://flybase.org/reports/FBgn0040647 protein_coding_gene - - - CG10987 - - 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0262272 mir-1002 mir-1002 stem loop http://flybase.org/reports/FBgn0262272 miRNA_gene - - - "mir-1002, 1002, miR-1002, CR42979, dme-miR-1002-5p" - CR42979 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0263468 snoRNA:SC35-a - http://flybase.org/reports/FBgn0263468 snoRNA_gene - - - "snoRNA:SC35-a, snoHACA_01" - CR43583 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0010334 X81 X81 http://flybase.org/reports/FBgn0010334 - gene - - - X81 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264348 lncRNA:CR43804 - http://flybase.org/reports/FBgn0264348 non_protein_coding_gene - - - CR43804 - CR43804 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265633 lncRNA:CR44440 - http://flybase.org/reports/FBgn0265633 non_protein_coding_gene - - - "CR44440, lincRNA.918" - CR44440 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266046 lncRNA:CR44811 - http://flybase.org/reports/FBgn0266046 non_protein_coding_gene - - - CR44811 - CR44811 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065746 l(2)SH0516 lethal (2) SH0516 http://flybase.org/reports/FBgn0065746 gene - - - "l(2)SH0516, l(2)SH2 0516" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0028427 Ilk Integrin linked kinase http://flybase.org/reports/FBgn0028427 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719 signal transducer activity ; GO:0004871 | inferred from biological aspect of ancestor with PANTHER:PTN000584058 protein kinase activity ; GO:0004672 | NOT inferred from key residues protein kinase activity ; GO:0004672 | non-traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with wech muscle attachment ; GO:0016203 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | NOT inferred from key residues cell-matrix adhesion ; GO:0007160 | inferred from mutant phenotype integrin-mediated signaling pathway ; GO:0007229 | inferred from biological aspect of ancestor with PANTHER:PTN001510364 substrate adhesion-dependent cell spreading ; GO:0034446 | inferred from biological aspect of ancestor with PANTHER:PTN001510364 cytoskeletal anchoring at plasma membrane ; GO:0007016 | inferred from sequence or structural similarity protein phosphorylation ; GO:0006468 | non-traceable author statement cell adhesion ; GO:0007155 | traceable author statement apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000584061 focal adhesion ; GO:0005925 | inferred from direct assay focal adhesion ; GO:0005925 | inferred from sequence or structural similarity stress fiber ; GO:0001725 | colocalizes_with inferred from biological aspect of ancestor with PANTHER:PTN001510364 "ILK, ilk, CG10504, CT29478, DmILK, l(3)78Ca, Ilk" "IPR000719:Protein kinase domain, IPR002110:Ankyrin repeat, IPR011009:Protein kinase-like domain, IPR020683:Ankyrin repeat-containing domain, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain" CG10504 27-Aug-18 DroID_v2018_08 Drer\ilk Scer\YGL242C "Cele\pat-4, Cele\F57B9.8, Cele\ZK622.1, Cele\kin-26" Xtro\ilk Mmus\Ilk Hsap\ILK "wild-type,lethal,visible,recessive,somatic clone,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of first instar larval stage,viable" "embryonic/larval somatic muscle,wing,somatic clone,muscle fiber,heat sensitive" FBgn0085732 CR40190 - http://flybase.org/reports/FBgn0085732 pseudogene_attribute - - - CR40190 - CR40190 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0026637 l(2)k13910 lethal (2) k13910 http://flybase.org/reports/FBgn0026637 - gene - - - l(2)k13910 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038678 mRpL55 mitochondrial ribosomal protein L55 http://flybase.org/reports/FBgn0038678 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:P0C2B8 structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with protein_id:BAB28535 mitochondrial translation ; GO:0032543 | traceable author statement translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:P0C2B8 mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with UniProtKB:P0C2B8 mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with protein_id:BAB28535 mitochondrion ; GO:0005739 | inferred from direct assay "tmb, CG14283, MRP-L55, BcDNA:RH10246, mRpL55" "IPR018615:Ribosomal protein L55, mitochondrial" CG14283 27-Aug-18 DroID_v2018_08 Drer\zgc:171480 - Cele\mrpl-55 - Mmus\Mrpl55 Hsap\MRPL55 "developmental rate defective,female sterile,germline clone,cell lethal,somatic clone,lethal - all die before end of first instar larval stage,some die during first instar larval stage,lethal,viable,fertile,visible" "actin filament | somatic cloneGMR.PU, cdiR47,trichogen cell" FBgn0264434 lncRNA:CR43852 - http://flybase.org/reports/FBgn0264434 non_protein_coding_gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype - CR43852 - CR43852 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0061196 CG15468 - http://flybase.org/reports/FBgn0061196 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG15468, SIP3" IPR031883:Protein of unknown function DUF4763 CG15468 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC18051 K -0.296428581 0.483790754 -0.315684127 0.350809764 2.246247079 1.091342566 FBgn0069327 X-146-21 X-146-21 http://flybase.org/reports/FBgn0069327 gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available X-146-21 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,germline clone,maternal effect,recessive,some die during embryonic stage" "embryonic head,germline clone,maternal effect,embryonic segment" FBgn0019986 Glt::Nrt Glt::Nrt http://flybase.org/reports/FBgn0019986 - engineered_fusion_gene - - - Glt::Nrt - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0025836 RhoGAP1A Rho GTPase activating protein at 1A http://flybase.org/reports/FBgn0025836 FBgn0026442 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from biological aspect of ancestor with PANTHER:PTN001142599 Rho guanyl-nucleotide exchange factor activity ; GO:0005089 | inferred from sequence or structural similarity with RhoGEF4 positive regulation of Rho protein signal transduction ; GO:0035025 | inferred from sequence or structural similarity with RhoGEF4 positive regulation of GTPase activity ; GO:0043547 | inferred from biological aspect of ancestor with PANTHER:PTN001142599 Golgi organization ; GO:0007030 | inferred from mutant phenotype negative regulation of cell size ; GO:0045792 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN001142599 "CG40494, EG:23E12.2, CG17960, EG:23E12.5, CG17617, BCR, CG40453, RhoGAP1A, rhoGAP1A, RhoGAP" "IPR000198:Rho GTPase-activating protein domain, IPR000219:Dbl homology (DH) domain, IPR001849:Pleckstrin homology domain, IPR008936:Rho GTPase activation protein, IPR000008:C2 domain, IPR011993:PH domain-like" CG40494 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-33c9.6, Drer\arhgap9, Drer\arhgap33, Drer\arhgap21b, Drer\si:ch211-253h3.1, Drer\arhgap23a, Drer\arhgap12a, Drer\arhgap31, Drer\bcr, Drer\arhgap32a, Drer\arhgap10, Drer\arhgap29a, Drer\arhgap27l, Drer\arhgap32b, Drer\arhgap15, Drer\chn2, Drer\si:dkey-91m11.5, Drer\LOC560371" "Scer\RGA1, Scer\BEM2, Scer\BEM3, Scer\RGD1, Scer\RGA2" "Cele\rrc-1, Cele\exc-5, Cele\spv-1, Cele\chin-1, Cele\tag-325, Cele\T04C9.1, Cele\rga-1, Cele\pac-1" "Xtro\arhgap26, Xtro\arhgap27, Xtro\bcr, Xtro\arhgap21, Xtro\abr" "Mmus\Arhgap9, Mmus\Arhgap33, Mmus\Chn2, Mmus\Bcr, Mmus\Abr, Mmus\Arhgap26, Mmus\Arhgap32, Mmus\Arhgap42, Mmus\Arhgap31, Mmus\Arhgap15, Mmus\Arhgap29, Mmus\Arhgap23, Mmus\Chn1, Mmus\Arhgap10, Mmus\Arhgap21, Mmus\Arhgap27" "Hsap\CHN1, Hsap\ARHGAP31, Hsap\ARHGAP42, Hsap\ARHGAP32, Hsap\ARHGAP9, Hsap\ABR, Hsap\ARHGAP23, Hsap\ARHGAP27, Hsap\ARHGAP26, Hsap\ARHGAP21, Hsap\ARHGAP33, Hsap\BCR, Hsap\ARHGAP29, Hsap\CHN2, Hsap\ARHGAP15, Hsap\ARHGAP10" viable FBgn0005216 l(3)ET7 lethal Elaine Tasaka 7 http://flybase.org/reports/FBgn0005216 - gene - - - l(3)ET7 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,cold sensitive,heat sensitive,male sterile" FBgn0058115 CG40115 - http://flybase.org/reports/FBgn0058115 protein_coding_gene - - - CG40115 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0058241 CG40241 - http://flybase.org/reports/FBgn0058241 protein_coding_gene - - - CG40241 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0045855 e(Pi3K92E)gamma e(Pi3K92E)gamma http://flybase.org/reports/FBgn0045855 gene - - - "gamma, e(Pi3K92E)gamma" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002255 l(3)68Eg lethal (3) 68Eg http://flybase.org/reports/FBgn0002255 - gene - - - "rsg17, l(3)rsg17, l(3)68Eg" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0037482 CG10055 - http://flybase.org/reports/FBgn0037482 protein_coding_gene unfolded protein binding ; GO:0051082 | inferred from biological aspect of ancestor with PANTHER:PTN000311574 box H/ACA snoRNP assembly ; GO:0000493 | inferred from biological aspect of ancestor with PANTHER:PTN000311574 ribonucleoprotein complex assembly ; GO:0022618 | inferred from sequence or structural similarity with UniProtKB:Q6PI26 nucleoplasm ; GO:0005654 | inferred from biological aspect of ancestor with PANTHER:PTN000311574 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000311574 "RE52393, CG10055" "IPR007009:SHQ1 protein, IPR015943:WD40/YVTN repeat-like-containing domain" CG10055 27-Aug-18 DroID_v2018_08 Drer\shq1 Scer\SHQ1 Cele\Y48A5A.1 Xtro\shq1 Mmus\Shq1 Hsap\SHQ1 viable FBgn0033374 CG13741 - http://flybase.org/reports/FBgn0033374 protein_coding_gene - - - "CG30346, CG13741" - CG13741 27-Aug-18 DroID_v2018_08 - - - - - - "visible,planar polarity defective,partially lethal - majority die,some die during pupal stage,female sterile" trichogen cell DRSC06412 K 0.335951901 0.588919752 0.262231959 0.200083419 3.851150831 1.058683071 FBgn0003272 rp rotated penis http://flybase.org/reports/FBgn0003272 - gene - - - rp - - 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,small body" "tergite,eye,leg,abdomen,male genitalia" FBgn0004091 l(2)60Cc lethal (2) 60Cc http://flybase.org/reports/FBgn0004091 - gene - - - l(2)60Cc - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005361 sx sexcombless http://flybase.org/reports/FBgn0005361 - gene - - - sx - - 27-Aug-18 DroID_v2018_08 - - - - - - male sterile "genitalia,clasper,penis,sex comb,macrochaeta,vulva,gonopod thorn bristle,anal plate,ovary,testis,metatarsus" FBgn0267768 asRNA:CR46099 - http://flybase.org/reports/FBgn0267768 non_protein_coding_gene - - - CR46099 - CR46099 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005135 l(1)Y107 lethal (1) Y107 http://flybase.org/reports/FBgn0005135 - gene - - - l(1)Y107 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" macrochaeta FBgn0001377 l(1)2Bh lethal (1) 2Bh http://flybase.org/reports/FBgn0001377 - gene - - - "HM40, l(1)HM40, l(1)2Bh" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0086066 snoRNA:Me5.8S-G74 - http://flybase.org/reports/FBgn0086066 snoRNA_gene - - - "snoRNA:Me5.8S-G74, Me5.8S-Gm74, Me5.8S-G74, CR34695" - CR34695 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033467 CG15863 - http://flybase.org/reports/FBgn0033467 protein_coding_gene - - - CG15863 IPR030482:p53 and DNA damage-regulated protein 1 CG15863 27-Aug-18 DroID_v2018_08 Drer\pdrg1 - Cele\T07D4.5 Xtro\pdrg1 Mmus\Pdrg1 Hsap\PDRG1 FBgn0085407 Pvf3 PDGF- and VEGF-related factor 3 http://flybase.org/reports/FBgn0085407 protein_coding_gene growth factor activity ; GO:0008083 | inferred from electronic annotation with InterPro:IPR000072 vascular endothelial growth factor receptor binding ; GO:0005172 | inferred from sequence or structural similarity with HGNC:12680 "hemocyte migration ; GO:0035099 | traceable author statement synaptic target recognition ; GO:0008039 | inferred from mutant phenotype hemocyte migration ; GO:0035099 | inferred from genetic interaction with Pvf2 salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype hemocyte migration ; GO:0035099 | inferred from expression pattern inferred from genetic interaction with Pvf1, Pvf2 vascular endothelial growth factor receptor signaling pathway ; GO:0048010 | inferred from sequence or structural similarity with HGNC:12680" membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR000072 "pvf3, CG34378, CG13783, PVF, CG4492, VEGF, PVFs, VEGF27Ca, CG13782, CG13781, Vegf27Ca, DmVEGF-3, CG31629, Pvf3, PVF3, Pvf" "IPR000072:PDGF/VEGF domain, IPR029034:Cystine-knot cytokine" CG34378 27-Aug-18 DroID_v2018_08 - - - - - - " embryonic stage | stage 9-11 , embryonic stage | stage 11-13 , embryonic stage | stage 9-15 " " posterior ectoderm

restricted , Malpighian tubule

, embryonic hindgut

, embryonic foregut

, ventral nerve cord

" """DRSC02284, DRSC02286"" " IK FBgn0014911 anon-4Fe anon-4Fe http://flybase.org/reports/FBgn0014911 - gene - - - anon-4Fe - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267725 asRNA:CR46058 - http://flybase.org/reports/FBgn0267725 non_protein_coding_gene - - - CR46058 - CR46058 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260113 2L3807 - http://flybase.org/reports/FBgn0260113 gene - - - 2L3807 - - 27-Aug-18 DroID_v2018_08 - - - - - - "terminal tracheal cell,somatic clone,embryonic/larval tracheal system" FBgn0053290 CG33290 - http://flybase.org/reports/FBgn0053290 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33290 - CG33290 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0034441 CG10081 - http://flybase.org/reports/FBgn0034441 protein_coding_gene - - - CG10081 IPR007484:Peptidase M28 CG10081 27-Aug-18 DroID_v2018_08 Drer\LOC100330918 "Scer\APE3, Scer\VPS70, Scer\PFF1, Scer\YDR415C" "Cele\B0495.7, Cele\C44B7.11" Xtro\ermp1 Mmus\Ermp1 Hsap\ERMP1 viable FBgn0027148 l(3)71CDb lethal (3) 71CDb http://flybase.org/reports/FBgn0027148 - gene - - - l(3)71CDb - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0014358 ms(3)HB665 ms(3)HB665 http://flybase.org/reports/FBgn0014358 - gene - - - ms(3)HB665 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005472 l(1)ts875 lethal (1) ts875 http://flybase.org/reports/FBgn0005472 - gene - - - l(1)ts875 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,heat sensitive" FBgn0011196 l(1)302-11 lethal (1) 302-11 http://flybase.org/reports/FBgn0011196 FBgn0010202 gene - - - "302-11, l(1)302-11" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0260815 EY10546 - http://flybase.org/reports/FBgn0260815 gene - - - EY10546 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030793 CG9125 - http://flybase.org/reports/FBgn0030793 protein_coding_gene 5'-3' exonuclease activity ; GO:0008409 | inferred from sequence or structural similarity with MGI:MGI:1890444 mRNA catabolic process ; GO:0006402 | inferred from sequence or structural similarity with MGI:MGI:1890444 nucleus ; GO:0005634 | inferred from sequence or structural similarity with MGI:MGI:1890444 "CG32566, CG9125, dRai1, Rai1" IPR013961:RAI1-like CG9125 27-Aug-18 DroID_v2018_08 Drer\dxo "Scer\DXO1, Scer\RAI1" "Cele\Y47H10A.4, Cele\M01G12.9, Cele\M01G12.14, Cele\F07H5.10, Cele\eol-1, Cele\Y47H10A.3, Cele\Y47H10A.5, Cele\C37H5.14, Cele\M01G12.7, Cele\dom-3" Xtro\dxo Mmus\Dxo Hsap\DXO FBgn0031142 r-cup ryder cup http://flybase.org/reports/FBgn0031142 protein_coding_gene - - - "CG10998, r-cup" IPR011990:Tetratricopeptide-like helical domain CG10998 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0004426 LysC Lysozyme C http://flybase.org/reports/FBgn0004426 FBgn0002575 pseudogene_attribute lysozyme activity ; GO:0003796 | inferred from electronic annotation with InterPro:IPR000974 - - "LysC, lysC, CG9111, CR9111, Lys C" "IPR000974:Glycoside hydrolase, family 22, lysozyme, IPR001916:Glycoside hydrolase, family 22, IPR019799:Glycoside hydrolase, family 22, conserved site, IPR023346:Lysozyme-like domain" CR9111 27-Aug-18 DroID_v2018_08 - - - - - - " adult stage , larval stage && adult stage , larval stage " " adult midgut

, embryonic/larval midgut

" FBgn0265576 CG44403 - http://flybase.org/reports/FBgn0265576 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44403 - CG44403 27-Aug-18 DroID_v2018_08 - - - Xtro\lbhd1 Mmus\1810009A15Rik Hsap\LBHD1 FBgn0003195 r(ADH) regulator of ADH http://flybase.org/reports/FBgn0003195 - gene - - - "r[26-43], r(ADH)" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266433 CG45063 - http://flybase.org/reports/FBgn0266433 protein_coding_gene nucleotide binding ; GO:0000166 | inferred from electronic annotation with InterPro:IPR008250 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR008250 - - "CG45063, CG3701" "IPR008250:P-type ATPase, A domain, IPR004014:Cation-transporting P-type ATPase, N-terminal" CG45063 27-Aug-18 DroID_v2018_08 "Drer\atp1a1a.1, Drer\atp1a3a, Drer\atp1a1b, Drer\atp2a3, Drer\atp1a1a.5, Drer\atp1a1a.3, Drer\si:dkey-28b4.8, Drer\atp2a2a, Drer\atp1a3b, Drer\atp2a1, Drer\atp2a2b, Drer\atp1a1a.4, Drer\atp1a2a, Drer\atp2a1l, Drer\atp1a1a.2" "Scer\PMA1, Scer\PMR1" "Cele\catp-3, Cele\sca-1, Cele\eat-6" "Xtro\atp12a, Xtro\atp1a3, Xtro\atp4a, Xtro\atp1a2, Xtro\atp1a1" "Mmus\Atp1a4, Mmus\Atp12a, Mmus\Atp2a1, Mmus\Atp4a, Mmus\Atp1a2, Mmus\Atp2a2, Mmus\Atp1a3, Mmus\Atp1a1, Mmus\Atp2a3" "Hsap\ATP1A2, Hsap\ATP4A, Hsap\ATP12A, Hsap\ATP1A3, Hsap\ATP1A4, Hsap\ATP1A1, Hsap\ATP2A1, Hsap\ATP2A2, Hsap\ATP2A3" FBgn0004933 a(2)48 abnormal abdomen (2) 48 http://flybase.org/reports/FBgn0004933 - gene - - - a(2)48 - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive,viable,good,fertile,maternal effect,wild-type" "tergite,sternite,adult abdomen" FBgn0053271 CG33271 - http://flybase.org/reports/FBgn0053271 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG6100, CG14139, CG32084, CG33271" - CG33271 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035471 Sc2 Sc2 http://flybase.org/reports/FBgn0035471 protein_coding_gene "oxidoreductase activity, acting on the CH-CH group of donors ; GO:0016627 | inferred from electronic annotation with InterPro:IPR001104 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN002238075" very long-chain fatty acid biosynthetic process ; GO:0042761 | inferred from biological aspect of ancestor with PANTHER:PTN000059180 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR001104 cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR001104 endomembrane system ; GO:0012505 | inferred from direct assay "dSc2, l(3)05634, l(3)63Eb, l(3)SH4, CG10849, Sc2, Ter[CG10849], SC2" "IPR001104:3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal, IPR000626:Ubiquitin domain, IPR029071:Ubiquitin-related domain" CG10849 27-Aug-18 DroID_v2018_08 "Drer\tecrl2b, Drer\tecrb, Drer\tecrl2a, Drer\tecra" Scer\TSC13 "Cele\art-1, Cele\F19H6.4" "Xtro\fam19a5, Xtro\tecr" "Mmus\Tecrl, Mmus\Tecr" "Hsap\TECRL, Hsap\TECR" "viable,lethal - all die before end of larval stage,some die during larval stage,lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0259665 B1350 - http://flybase.org/reports/FBgn0259665 gene - - - B1350 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "leg,tarsal segment" FBgn0005586 Rab3 Rab3 http://flybase.org/reports/FBgn0005586 - protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579, InterPro:IPR005225 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11" maintenance of presynaptic active zone structure ; GO:0048790 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | non-traceable author statement regulation of short-term neuronal synaptic plasticity ; GO:0048172 | inferred from sequence or structural similarity with UniProtKB:P63011 regulation of synaptic vesicle fusion to presynaptic membrane ; GO:0031630 | inferred from sequence or structural similarity with UniProtKB:P63011 vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 neurotransmitter secretion ; GO:0007269 | non-traceable author statement Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 cytoskeletal matrix organization at active zone ; GO:0048789 | inferred from mutant phenotype synaptic vesicle ; GO:0008021 | non-traceable author statement synapse ; GO:0045202 | inferred from direct assay presynaptic active zone ; GO:0048786 | inferred from direct assay synaptic vesicle ; GO:0008021 | inferred from direct assay presynaptic active zone ; GO:0048786 | colocalizes_with inferred from direct assay vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 synaptic vesicle ; GO:0008021 | colocalizes_with inferred from direct assay "DRab3, dm-Rab3, AAF58762, DmRab3, drab3, rab3, Rab3A, Drab3, DRAB3, CG7576, Rab3, P25228" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG7576 27-Aug-18 DroID_v2018_08 "Drer\rab3c, Drer\rab3db, Drer\rab3ab, Drer\rab3da, Drer\rab3aa, Drer\rab3b" "Scer\YHR022C, Scer\SEC4, Scer\YPT1" "Cele\rab-3, Cele\prmt-4" "Xtro\rab3d, Xtro\rab3c, Xtro\rab3b, Xtro\rab3a" "Mmus\Rab3a, Mmus\Rab3c, Mmus\Rab3b, Mmus\Rab3d" "Hsap\RAB3B, Hsap\RAB3D, Hsap\RAB3C, Hsap\RAB3A" " embryonic stage | stage >=13 , embryonic stage -- adult stage , adult stage " " antenno-maxillary complex

, embryonic central nervous system

, cell body &&of adult brain

" "neuroanatomy defective,neurophysiology defective,viable,fertile" "t-bar,neuromuscular junctionED2076)" FBgn0024560 l(3)L5340 lethal (3) L5340 http://flybase.org/reports/FBgn0024560 - gene - - - l(3)L5340 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0085339 CG34310 - http://flybase.org/reports/FBgn0085339 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34310 - CG34310 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0067102 GlcT Ceramide glucosyltransferase http://flybase.org/reports/FBgn0067102 protein_coding_gene ceramide glucosyltransferase activity ; GO:0008120 | inferred from direct assay glucosylceramide biosynthetic process ; GO:0006679 | inferred from biological aspect of ancestor with PANTHER:PTN000296098 negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype Golgi membrane ; GO:0000139 | inferred from direct assay endoplasmic reticulum membrane ; GO:0005789 | inferred from direct assay "DGlcT-1, CG6437, GlcT-1, GlcT, GlcT1, dGlcCerT" "IPR029044:Nucleotide-diphospho-sugar transferases, IPR025993:Ceramide glucosyltransferase" CG6437 27-Aug-18 DroID_v2018_08 Drer\ugcg - "Cele\cgt-2, Cele\cgt-3, Cele\T06C12.12, Cele\cgt-1" Xtro\ugcg Mmus\Ugcg Hsap\UGCG "increased cell death,visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0065321 l(2)SH1916 lethal (2) SH1916 http://flybase.org/reports/FBgn0065321 gene - - - "l(2)SH1916, l(2)SH2 1916" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0263484 snoRNA:Pi4KIIalpha-a - http://flybase.org/reports/FBgn0263484 snoRNA_gene - - - "snoRNA:Pi4KIIalpha-a, snoRNA:Pl4KIIalpha-a" - CR43599 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0058044 CG40044 - http://flybase.org/reports/FBgn0058044 protein_coding_gene - - - CG40044 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264351 lncRNA:CR43807 - http://flybase.org/reports/FBgn0264351 non_protein_coding_gene - - - CR43807 - CR43807 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266759 shg::Rnor\Cd2::alpha-Cat - http://flybase.org/reports/FBgn0266759 engineered_fusion_gene - - - shg::Rnor\CD2::alpha-Cat - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039943 CG17168 - http://flybase.org/reports/FBgn0039943 protein_coding_gene mRNA binding ; GO:0003729 | inferred from biological aspect of ancestor with PANTHER:PTN002359305 RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:30587 production of miRNAs involved in gene silencing by miRNA ; GO:0035196 | inferred from biological aspect of ancestor with PANTHER:PTN001152383 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000592573 CG17168 "IPR000253:Forkhead-associated (FHA) domain, IPR008984:SMAD/FHA domain" CG17168 27-Aug-18 DroID_v2018_08 Drer\snip1 Scer\PML1 Cele\C32E8.5 Xtro\snip1 Mmus\Snip1 Hsap\SNIP1 DRSC20904 K -0.571545314 0.498556612 -1.031827048 0.103853398 -2.895701975 -1.729738696 FBgn0036028 CG16717 - http://flybase.org/reports/FBgn0036028 protein_coding_gene hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR004843 - - CG16717 "IPR024201:Calcineurin-like phosphoesterase, IPR004843:Calcineurin-like phosphoesterase domain, ApaH type, IPR029052:Metallo-dependent phosphatase-like" CG16717 27-Aug-18 DroID_v2018_08 "Drer\mpped2, Drer\mpped1, Drer\mpped2a" - "Cele\T07D4.2, Cele\C25E10.12, Cele\K07C11.7" Xtro\mpped2 "Mmus\Mpped2, Mmus\Mpped1" "Hsap\MPPED1, Hsap\MPPED2" viable FBgn0262947 CG43266 - http://flybase.org/reports/FBgn0262947 protein_coding_gene - - - CG43266 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004641 E(sev)3D Enhancer of sevenless 3D http://flybase.org/reports/FBgn0004641 - gene - - - "H214, E(sev)3D" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0001359 l(1)1EFh lethal (1) 1EFh http://flybase.org/reports/FBgn0001359 - gene - - - "l(1)BA8, l(1)1EFh" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0266753 lncRNA:CR45226 - http://flybase.org/reports/FBgn0266753 non_protein_coding_gene - - - CR45226 - CR45226 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065941 l(2)SH0115 lethal (2) SH0115 http://flybase.org/reports/FBgn0065941 gene - - - "l(2)SH0115, l(2)SH2 0115" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0019663 ply paisley http://flybase.org/reports/FBgn0019663 - gene - - - ply - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive,cold sensitive" wing hair FBgn0028623 l(2)05095a lethal (2) 05095a http://flybase.org/reports/FBgn0028623 gene - - - "l(2)05095, l(2)05095a" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0014860 Lcch2 Ligand-gated chloride channel homolog 2 http://flybase.org/reports/FBgn0014860 - gene - - - "LCCH2, Lcch2" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267638 lncRNA:CR45976 - http://flybase.org/reports/FBgn0267638 non_protein_coding_gene - - - CR45976 - CR45976 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0017429 CG5989 - http://flybase.org/reports/FBgn0017429 - protein_coding_gene ribosome binding ; GO:0043022 | inferred from electronic annotation with InterPro:IPR033122 cellular metal ion homeostasis ; GO:0006875 | inferred from biological aspect of ancestor with PANTHER:PTN000360953 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000360956 "anon-66Db, CG5989" "IPR011685:LETM1-like, IPR003100:PAZ domain, IPR033122:Letm1 ribosome-binding domain" CG5989 27-Aug-18 DroID_v2018_08 Drer\letmd1 "Scer\MDM38, Scer\YLH47" Cele\F30F8.9 Xtro\letmd1 Mmus\Letmd1 Hsap\LETMD1 viable FBgn0065423 l(2)SH1519 lethal (2) SH1519 http://flybase.org/reports/FBgn0065423 gene - - - "l(2)SH1519, l(2)SH2 1519" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0051665 wry weary http://flybase.org/reports/FBgn0051665 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097 Notch binding ; GO:0005112 | inferred from physical interaction with N" heart process ; GO:0003015 | inferred from mutant phenotype Notch signaling pathway ; GO:0007219 | inferred from mutant phenotype cell surface ; GO:0009986 | inferred from direct assay "CT35769, CG15621, CG12704, wry, CG31665" "IPR000152:EGF-type aspartate/asparagine hydroxylation site, IPR000742:EGF-like domain, IPR001881:EGF-like calcium-binding domain, IPR013032:EGF-like, conserved site, IPR009030:Growth factor receptor cysteine-rich domain, IPR018097:EGF-like calcium-binding, conserved site" CG31665 27-Aug-18 DroID_v2018_08 "Drer\dner, Drer\si:dkey-163f14.6" - - Xtro\dner "Mmus\Dner, Mmus\Dll3" "Hsap\NOTCH2NL, Hsap\DLL3, Hsap\DNER" viable "adult heart,heat sensitive" DRSC00456 K 0.223670984 0.796397097 0.082206128 0.636242073 -0.640880008 -1.553549396 FBgn0000510 Dt Detached http://flybase.org/reports/FBgn0000510 - gene - - - Dt - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036484 Pex3 Peroxin 3 http://flybase.org/reports/FBgn0036484 protein_coding_gene - peroxisome organization ; GO:0007031 | inferred from mutant phenotype fatty acid elongation ; GO:0030497 | inferred from mutant phenotype peroxisome organization ; GO:0007031 | inferred from sequence or structural similarity with HGNC:8858 positive regulation of ceramide biosynthetic process ; GO:2000304 | inferred from mutant phenotype integral component of peroxisomal membrane ; GO:0005779 | inferred from electronic annotation with InterPro:IPR006966 peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:8858 "CG6859, pex3, Pex3, DmelPex3, PEX3" IPR006966:Peroxin-3 CG6859 27-Aug-18 DroID_v2018_08 "Drer\pex3, Drer\runx1" Scer\PEX3 "Cele\rnt-1, Cele\prx-3" "Xtro\pex3, Xtro\runx3" Mmus\Pex3 "Hsap\PEX3, Hsap\RUNX3" "viable,lethal - all die before end of larval stage,recessive,some die during larval stage" peroxisome DRSC10731 K -0.061623959 -0.277858694 0.260979855 1.005999907 2.022460592 0.286486407 FBgn0084764 EP3123 EP3123 http://flybase.org/reports/FBgn0084764 gene - - - EP3123 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036177 CG33268 - http://flybase.org/reports/FBgn0036177 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG14138, CG33268" - CG33268 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265536 asRNA:CR44386 - http://flybase.org/reports/FBgn0265536 non_protein_coding_gene - - - "CR44386, lincRNA.331" - CR44386 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036348 CG17687 - http://flybase.org/reports/FBgn0036348 protein_coding_gene - - - CG17687 "IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG17687 27-Aug-18 DroID_v2018_08 Drer\cfap43 Scer\SMC2 - - Mmus\Cfap43 Hsap\CFAP43 FBgn0036872 CG12519 - http://flybase.org/reports/FBgn0036872 protein_coding_gene - - - CG12519 - CG12519 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0029874 CG3342 - http://flybase.org/reports/FBgn0029874 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG3342 - CG3342 27-Aug-18 DroID_v2018_08 - - - - - Hsap\FKBP15 "viable,fertile" FBgn0005241 l(3)R88 lethal of Roberts 88 http://flybase.org/reports/FBgn0005241 - gene - - - "l(3)B88, l(3)R88" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,polyphasic,recessive" FBgn0003221 rdp reduplicated http://flybase.org/reports/FBgn0003221 - gene - - - rdp - - 27-Aug-18 DroID_v2018_08 - - - - - - "leg,cold sensitive" FBgn0267778 asRNA:CR46109 - http://flybase.org/reports/FBgn0267778 non_protein_coding_gene - - - CR46109 - CR46109 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040352 CG14416 - http://flybase.org/reports/FBgn0040352 protein_coding_gene - - - "EG:BACR43E12.7, CG14416" - CG14416 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065129 l(3)SH134 lethal (3) SH134 http://flybase.org/reports/FBgn0065129 gene - - - "l(3)SH134, l(2)SH3 134" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0267532 asRNA:CR45872 - http://flybase.org/reports/FBgn0267532 non_protein_coding_gene - - - CR45872 - CR45872 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0022815 E(faf)E1051 Enhancer of faf E1051 http://flybase.org/reports/FBgn0022815 - gene - - - E(faf)E1051 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0022380 Pt-10A Adult protein-10A http://flybase.org/reports/FBgn0022380 - gene - - - Pt-10A - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065222 l(2)SH2226 lethal (2) SH2226 http://flybase.org/reports/FBgn0065222 gene - - - "l(2)SH2226, l(2)SH2 2226" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0016764 anon-17Ca anon-17Ca http://flybase.org/reports/FBgn0016764 - gene - - - "C1, anon-17Ca" - - 27-Aug-18 DroID_v2018_08 - - - - - - embryonic stage -- adult stage FBgn0023170 RpL39 Ribosomal protein L39 http://flybase.org/reports/FBgn0023170 FBgn0047027 protein_coding_gene "structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR000077, InterPro:IPR020083 RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000463054 structural constituent of ribosome ; GO:0003735 | traceable author statement" "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR000077, InterPro:IPR020083 cytoplasmic translation ; GO:0002181 | traceable author statement" "ribosome ; GO:0005840 | inferred from electronic annotation with InterPro:IPR000077, InterPro:IPR020083 cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement" "RpL46, L39, RPl46, Rp46, rp46, anon-EST:Posey16, CG3997, BcDNA:RH27094, RpL39" "IPR020083:Ribosomal protein L39e, conserved site, IPR000077:Ribosomal protein L39e, IPR023626:Ribosomal protein L39e domain" CG3997 27-Aug-18 DroID_v2018_08 Drer\rpl39 Scer\RPL39 Cele\rpl-39 Xtro\rpl39 "Mmus\Rpl39l, Mmus\Rpl39" "Hsap\RPL39, Hsap\RPL39L" " embryonic stage , embryonic stage -- adult stage "

ubiquitous "lethal - all die before end of pupal stage,some die during pupal stage" DRSC04651 IEK -2.2505861 -2.415181306 3.139503081 -4.523638653 2.810435677 2.640578618 FBgn0010241 Mdr50 Multi drug resistance 50 http://flybase.org/reports/FBgn0010241 "FBtr0087537, FBpp0086666" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR011527, InterPro:IPR017871 xenobiotic-transporting ATPase activity ; GO:0008559 | inferred from sequence or structural similarity with UniProtKB:Q00748 efflux transmembrane transporter activity ; GO:0015562 | inferred from sequence or structural similarity with UniProtKB:Q00748" transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011527 response to toxic substance ; GO:0009636 | inferred from expression pattern xenobiotic transport ; GO:0042908 | inferred from sequence or structural similarity with UniProtKB:Q00748 renal tubular secretion ; GO:0097254 | inferred from expression pattern ATP-binding cassette (ABC) transporter complex ; GO:0043190 | inferred from sequence or structural similarity with UniProtKB:Q00748 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with UniProtKB:Q00748 "CG8523, MDR50, Dm3, Dm2, Mdr50, mdr50" "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR011527:ABC transporter type 1, transmembrane domain, IPR017871:ABC transporter, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG8523 27-Aug-18 DroID_v2018_08 "Drer\abcb4, Drer\abcb11a, Drer\abcb9, Drer\abcb3l1, Drer\abcb5, Drer\abcb10, Drer\abcb11b, Drer\abcb8" Scer\STE6 "Cele\haf-3, Cele\haf-2, Cele\haf-4, Cele\haf-9, Cele\pgp-1, Cele\pgp-2, Cele\pgp-11, Cele\pgp-10, Cele\pgp-3, Cele\haf-1, Cele\pgp-6, Cele\haf-6, Cele\haf-8, Cele\pgp-9, Cele\pgp-7, Cele\pgp-5, Cele\pgp-14, Cele\haf-7, Cele\pgp-13, Cele\pgp-8, Cele\pgp-12, Cele\pgp-4" "Xtro\LOC100496268, Xtro\LOC100494740, Xtro\abcb8" "Mmus\Abcb5, Mmus\Abcb9, Mmus\Abcb8, Mmus\Abcb11, Mmus\Abcb10, Mmus\Abcb1a, Mmus\Abcb1b, Mmus\Abcb4" "Hsap\ABCB10, Hsap\ABCB11, Hsap\ABCB1, Hsap\ABCB8, Hsap\ABCB5, Hsap\ABCB4" adult stage DRSC07467 IE 1.981677106 0.106965008 2.428400612 0.396501141 -0.250017016 0.060573317 FBgn0002908 mus311 mutagen-sensitive 311 http://flybase.org/reports/FBgn0002908 - gene - - - mus311 - - 27-Aug-18 DroID_v2018_08 - - - - - - "chemical sensitive,recessive,female sterile,DNA repair defective" FBgn0266836 lncRNA:CR45298 - http://flybase.org/reports/FBgn0266836 non_protein_coding_gene - - - CR45298 - CR45298 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264430 lncRNA:CR43848 - http://flybase.org/reports/FBgn0264430 non_protein_coding_gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype - CR43848 - CR43848 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060553 l(3)S097613b lethal (3) S097613b http://flybase.org/reports/FBgn0060553 gene - - - "0976/13, l(3)S097613b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0260309 GSd411 - http://flybase.org/reports/FBgn0260309 gene - - - GSd411 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,neuroanatomy defective" ventral nerve cord FBgn0000876 fs(1)M74 female sterile (1) M74 http://flybase.org/reports/FBgn0000876 - gene - - - fs(1)M74 - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive,lethal,maternal effect" FBgn0261931 CG42797 - http://flybase.org/reports/FBgn0261931 protein_coding_gene ubiquitin protein ligase activity ; GO:0061630 | inferred from sequence or structural similarity with Nedd4 protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with Nedd4 cellular_component ; GO:0005575 | no biological data available "CG3099, CG42797, CG3003, BT058014.1" "IPR001202:WW domain, IPR000569:HECT domain" CG42797 27-Aug-18 DroID_v2018_08 "Drer\hecw1b, Drer\LOC100334952, Drer\LOC100534749, Drer\yap1, Drer\itcha, Drer\bag3, Drer\wwtr1, Drer\hecw2a, Drer\nedd4a, Drer\smurf2, Drer\LOC103909734, Drer\nedd4l, Drer\hecw2b, Drer\smurf1, Drer\wwp2" "Scer\RSP5, Scer\TOM1" Cele\hecw-1 "Xtro\bag3, Xtro\itch, Xtro\hecw1, Xtro\smurf1, Xtro\wwp2, Xtro\nedd4, Xtro\nedd4l" "Mmus\Yap1, Mmus\Bag3, Mmus\Hecw2, Mmus\Smurf2, Mmus\Gas7, Mmus\Nedd4l, Mmus\Smurf1, Mmus\Nedd4, Mmus\Hecw1, Mmus\Wwp1, Mmus\Itch, Mmus\Wwp2" "Hsap\HECW2, Hsap\NEDD4, Hsap\SMURF2, Hsap\GAS7, Hsap\WWP2, Hsap\HECW1, Hsap\WWP1, Hsap\SMURF1, Hsap\BAG3, Hsap\ITCH, Hsap\YAP1, Hsap\NEDD4L" FBgn0261274 Ero1L Endoplasmic reticulum oxidoreductin-1-like http://flybase.org/reports/FBgn0261274 protein_coding_gene "oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor ; GO:0016671 | inferred from electronic annotation with InterPro:IPR007266 protein disulfide oxidoreductase activity ; GO:0015035 | inferred from biological aspect of ancestor with PANTHER:PTN000289179 protein disulfide isomerase activity ; GO:0003756 | inferred from biological aspect of ancestor with PANTHER:PTN000289179 oxidoreductase activity ; GO:0016491 | inferred from sequence or structural similarity with UniProtKB:Q96HE7" oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR007266 protein folding in endoplasmic reticulum ; GO:0034975 | inferred from biological aspect of ancestor with PANTHER:PTN000289179 chaperone mediated protein folding requiring cofactor ; GO:0051085 | inferred from sequence or structural similarity with UniProtKB:Q96HE7 cellular protein modification process ; GO:0006464 | inferred from biological aspect of ancestor with PANTHER:PTN000289179 endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN000289179 endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with UniProtKB:Q96HE7 "kiga, ERO1-L, CG1333, Ero1L, l(3)SH22, l(3)64Ag, Ero1l, ero1L" IPR007266:Endoplasmic reticulum oxidoreductin 1 CG1333 27-Aug-18 DroID_v2018_08 "Drer\ero1a, Drer\ero1b" Scer\ERO1 Cele\ero-1 "Xtro\ero1a, Xtro\ero1b" "Mmus\Ero1l, Mmus\Ero1lb" "Hsap\ERO1B, Hsap\ERO1A" FBgn0033894 CG13352 - http://flybase.org/reports/FBgn0033894 protein_coding_gene - - - CG13352 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035585 ATPsynCF6L "ATP synthase, coupling factor 6-like" http://flybase.org/reports/FBgn0035585 protein_coding_gene hydrogen ion transmembrane transporter activity ; GO:0015078 | inferred from electronic annotation with InterPro:IPR008387 ATPase activity ; GO:0016887 | contributes_to inferred from sequence or structural similarity with HGNC:847 ATP synthesis coupled proton transport ; GO:0015986 | inferred from electronic annotation with InterPro:IPR008387 ATP metabolic process ; GO:0046034 | inferred from sequence or structural similarity with RGD:621376 "mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) ; GO:0000276 | inferred from sequence or structural similarity with RGD:621376" "CG12027, ATPR, ATPsynCF6L" "IPR008387:ATP synthase-coupling factor 6, mitochondrial" CG12027 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-22n8.3, Drer\si:ch211-140m22.7, Drer\atp5j" - Cele\atp-4 Xtro\atp5j Mmus\Atp5j Hsap\ATP5J DRSC08232 I 1.950521044 0.614457678 0.223087393 0.220130787 0.276438355 -0.33536531 FBgn0051803 CG31803 - http://flybase.org/reports/FBgn0051803 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cilium movement involved in cell motility ; GO:0060294 | inferred from biological aspect of ancestor with PANTHER:PTN000498841 axoneme assembly ; GO:0035082 | inferred from biological aspect of ancestor with PANTHER:PTN000498841 motile cilium assembly ; GO:0044458 | inferred from biological aspect of ancestor with PANTHER:PTN000498841 cellular_component ; GO:0005575 | no biological data available "BcDNA:AT29119, CG31803" - CG31803 27-Aug-18 DroID_v2018_08 Drer\rsph9 - - Xtro\rsph9 Mmus\Rsph9 Hsap\RSPH9 partially lethal - majority die FBgn0263523 mir-4972 mir-4972 stem loop http://flybase.org/reports/FBgn0263523 miRNA_gene - - - "mir-4972, dme-mir-4972, CR43508" - CR43508 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266989 lncRNA:CR45440 - http://flybase.org/reports/FBgn0266989 non_protein_coding_gene - - - CR45440 - CR45440 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265076 lncRNA:CR44187 - http://flybase.org/reports/FBgn0265076 non_protein_coding_gene - - - CR44187 - CR44187 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0052167 CG32167 - http://flybase.org/reports/FBgn0052167 protein_coding_gene - - - CG32167 - - 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0040133 l(2)22Af lethal (2) 22Af http://flybase.org/reports/FBgn0040133 gene - - - "T, l(2)22Af" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0005405 l(1)10Ch lethal (1) 10Ch http://flybase.org/reports/FBgn0005405 - gene - - - "l(1)JC35, l(1)10Ch" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0036498 CG13455 - http://flybase.org/reports/FBgn0036498 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13455 - CG13455 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" FBgn0026876 CG11403 - http://flybase.org/reports/FBgn0026876 - protein_coding_gene "ATP-dependent DNA helicase activity ; GO:0004003 | inferred from electronic annotation with InterPro:IPR006554, InterPro:IPR010614 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR006555, InterPro:IPR010614, InterPro:IPR014013 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR010614 helicase activity ; GO:0004386 | inferred from sequence or structural similarity" nucleobase-containing compound metabolic process ; GO:0006139 | inferred from electronic annotation with InterPro:IPR006555 - "EG:33C11.2, cg11403, CG11403" "IPR006555:ATP-dependent helicase, C-terminal, IPR013020:DNA helicase (DNA repair), Rad3 type, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR014013:Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type, IPR010614:DEAD2, IPR006554:Helicase-like, DEXD box c2 type" CG11403 27-Aug-18 DroID_v2018_08 Drer\ddx11 Scer\CHL1 Cele\chl-1 Xtro\ddx11 Mmus\Ddx11 Hsap\DDX11 "viable,fertile" FBgn0027183 l(2)60A-K lethal (2) 60A-K http://flybase.org/reports/FBgn0027183 - gene - - - l(2)60A-K - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0026162 tRNA:Lys-TTT-2-1 transfer RNA:Lysine-TTT 2-1 http://flybase.org/reports/FBgn0026162 "FBgn0003793, FBgn0011901, FBgn0051490, FBgn0060174" tRNA_gene AAA codon-amino acid adaptor activity ; GO:0033443 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033443 cytosol ; GO:0005829 | inferred by curator from GO:0033443 "CR31490, lys5:84ABd, AE002699.trna8-LysTTT, tRNA:K:TTT:AE002699-c, tRNA:K5, BG:DS00276.4, chr3R.trna2-LysTTT, tRNA-Lys-TTT-2-1, tRNA:Lys-TTT-2-1, tRNA:K5:84ABd, AAA" - CR31490 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037912 sea scheggia http://flybase.org/reports/FBgn0037912 protein_coding_gene citrate transmembrane transporter activity ; GO:0015137 | inferred from biological aspect of ancestor with PANTHER:PTN001182669 mitochondrial citrate transport ; GO:0006843 | inferred from mutant phenotype citrate transport ; GO:0015746 | inferred from direct assay mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000640552 Nebenkern ; GO:0016006 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 "CG31305, anon-WO0140519.12, sea, CG6782, SLC25A1, l(3)EP3364, DmCIC, Sea" "IPR018108:Mitochondrial substrate/solute carrier, IPR023395:Mitochondrial carrier domain" CG6782 27-Aug-18 DroID_v2018_08 "Drer\slc25a1b, Drer\si:dkey-178e17.1, Drer\slc25a1a" "Scer\SFC1, Scer\CTP1, Scer\YHM2, Scer\YFR045W" "Cele\K11H3.3, Cele\Y37B11A.3" Xtro\slc25a1 Mmus\Slc25a1 Hsap\SLC25A1 "mitotic cell cycle defective,lethal,viable" "condensed chromosome,embryonic/larval neuroblast,condensed chromosomeMx-1)" FBgn0004750 l(3)89Bc lethal (3) 89Bc http://flybase.org/reports/FBgn0004750 - gene - - - l(3)89Bc - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0033019 CG10395 - http://flybase.org/reports/FBgn0033019 protein_coding_gene - "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR029523 chromatin remodeling ; GO:0006338 | inferred from electronic annotation with InterPro:IPR029523" "Ino80 complex ; GO:0031011 | inferred from electronic annotation with InterPro:IPR006880, InterPro:IPR029523" "CG10395, mdcds_12730" "IPR007529:Zinc finger, HIT-type, IPR029523:INO80 complex, subunit Ies2, IPR006880:INO80 complex subunit B-like conserved region" CG10395 27-Aug-18 DroID_v2018_08 Drer\ino80b Scer\IES2 - Xtro\ino80b Mmus\Ino80b "Hsap\INO80B, Hsap\WBP1" "viable,body color defective" mesothoracic tergum FBgn0011866 tRNA:Gly-GCC-2-1 transfer RNA:Glycine-GCC 2-1 http://flybase.org/reports/FBgn0011866 "FBgn0003779, FBgn0051980, FBgn0060222" tRNA_gene GGC codon-amino acid adaptor activity ; GO:0033462 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033462 cytosol ; GO:0005829 | inferred by curator from GO:0033462 "BG:DS04641.7, AE002690.trna15-GlyGCC, tRNA:G:GCC:AE002690-c, CR31980, tRNA:gly3:35Be, tRNA[Gly-GCC], chr2L.trna24-GlyGCC, tRNA-Gly-GCC-2-1, tRNA:Gly-GCC-2-1, tRNA:G3:35Be, GGC" - CR31980 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0066348 l(3)99DEg lethal (3) 99DEg http://flybase.org/reports/FBgn0066348 gene - - - l(3)99DEg - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0263497 lncRNA:CR43486 - http://flybase.org/reports/FBgn0263497 non_protein_coding_gene - - - "CR43486, lincRNA.695" - CR43486 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259831 CG34309 - http://flybase.org/reports/FBgn0259831 protein_coding_gene - - - "CG34309, CG14378, Dm_3R:49679, Dm_3R:49681" - CG34309 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0010013 Canp Ca[2+]-activated neutral protease http://flybase.org/reports/FBgn0010013 - gene calcium-dependent cysteine-type endopeptidase activity ; GO:0004198 | inferred from direct assay - - "CANP, nCAPII, Ca-TPase, Canp" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051776 CG31776 - http://flybase.org/reports/FBgn0051776 protein_coding_gene polypeptide N-acetylgalactosaminyltransferase activity ; GO:0004653 | inferred from sequence or structural similarity with UniProtKB:Q6WV20 oligosaccharide biosynthetic process ; GO:0009312 | inferred from sequence or structural similarity with UniProtKB:Q6WV20 - "CG8845a, CG8845, CG31776, dppGalNAcT10" "IPR000772:Ricin B, lectin domain, IPR001173:Glycosyltransferase 2-like, IPR029044:Nucleotide-diphospho-sugar transferases" CG31776 27-Aug-18 DroID_v2018_08 "Drer\galnt18b, Drer\galnt7, Drer\galnt16, Drer\poc1bl, Drer\LOC101886587, Drer\galnt12, Drer\LOC100334784, Drer\wbscr17, Drer\galnt3, Drer\galnt2, Drer\galnt8a.1, Drer\LOC568645, Drer\LOC100535692, Drer\LOC101882942, Drer\galnt11, Drer\si:ch211-15e22.3, Drer\galnt9, Drer\galnt6, Drer\galnt8b, Drer\galnt13, Drer\galnt1, Drer\galnt10, Drer\LOC103910015, Drer\galnt14" - "Cele\gly-9, Cele\gly-7, Cele\gly-11, Cele\gly-10, Cele\gly-3" "Xtro\galnt6.1, Xtro\galnt1, Xtro\galnt12, Xtro\galnt9, Xtro\galnt7, Xtro\galnt2, Xtro\galnt4, Xtro\galnt15, Xtro\galnt16, Xtro\galnt13, Xtro\galnt14, Xtro\wbscr17, Xtro\galnt10" "Mmus\Galntl5, Mmus\Wbscr17, Mmus\Galntl6, Mmus\Galnt16, Mmus\Galnt13, Mmus\Galnt18, Mmus\Galnt2, Mmus\Galnt12, Mmus\Galnt14, Mmus\Galnt5, Mmus\Galnt9, Mmus\Galnt4, Mmus\Galnt10, Mmus\Galnt15, Mmus\Galnt3, Mmus\Galnt11, Mmus\Galnt6, Mmus\Galnt1, Mmus\Galnt7" "Hsap\GALNT16, Hsap\GALNT4, Hsap\GALNT11, Hsap\GALNT7, Hsap\GALNT13, Hsap\GALNT5, Hsap\GALNT3, Hsap\GALNT18, Hsap\GALNT10, Hsap\GALNT9, Hsap\GALNT6, Hsap\GALNT15, Hsap\GALNT2, Hsap\GALNTL5, Hsap\GALNT8, Hsap\GALNT14, Hsap\GALNTL6, Hsap\WBSCR17, Hsap\GALNT12, Hsap\POC1B-GALNT4, Hsap\GALNT1" viable FBgn0032670 CG5783 - http://flybase.org/reports/FBgn0032670 protein_coding_gene N-acetyltransferase activity ; GO:0008080 | inferred from electronic annotation with InterPro:IPR000182 - - CG5783 "IPR000182:GNAT domain, IPR016181:Acyl-CoA N-acyltransferase, IPR013653:FR47-like" CG5783 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-76k16.5, Drer\si:dkey-76k16.6, Drer\si:ch73-106k19.2" Scer\TEM1 "Cele\ZK185.3, Cele\gip-1, Cele\let-756" - "Mmus\Keg1, Mmus\Glyatl3, Mmus\Glyat, Mmus\Rin1, Mmus\Gm4952" "Hsap\GLYAT, Hsap\RIN1, Hsap\GLYATL3, Hsap\TSC1, Hsap\GLYATL1, Hsap\GLYATL2" viable FBgn0053911 CG33911 - http://flybase.org/reports/FBgn0053911 protein_coding_gene - - - "BG:DS07295.4, DS07295.4, CG33911" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266277 asRNA:CR44962 - http://flybase.org/reports/FBgn0266277 non_protein_coding_gene - - - CR44962 - CR44962 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039765 mRpS18C mitochondrial ribosomal protein S18C http://flybase.org/reports/FBgn0039765 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:Q9Y3D5 mitochondrial translation ; GO:0032543 | traceable author statement translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:Q9Y3D5 mitochondrial small ribosomal subunit ; GO:0005763 | traceable author statement cytosolic small ribosomal subunit ; GO:0022627 | inferred from biological aspect of ancestor with PANTHER:PTN000336666 mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:Q9Y3D5 "mRpS18a, CG9688, MRP-S18-(1), mRpS18C" IPR001648:Ribosomal protein S18 CG9688 27-Aug-18 DroID_v2018_08 "Drer\mrps18b, Drer\mrps18c, Drer\mrps18a" Scer\RSM18 "Cele\T14B4.2, Cele\iglr-2" Xtro\mrps18c "Mmus\Mrps18a, Mmus\Mrps18c" "Hsap\MRPS18C, Hsap\MRPS18A" "viable,visible" trichogen cell FBgn0264725 CG43993 - http://flybase.org/reports/FBgn0264725 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43993 - CG43993 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265424 lncRNA:TS14 long noncoding RNA: testis-specific 14 http://flybase.org/reports/FBgn0265424 non_protein_coding_gene - - - "lncRNA:TS14, CR44336" - CR44336 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001761 l(1)M16 lethal (1) M16 http://flybase.org/reports/FBgn0001761 - gene - - - l(1)M16 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0259525 GG01477 - http://flybase.org/reports/FBgn0259525 gene - - - GG01477 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "anterior crossvein,wing vein L3,tarsal segment" FBgn0028186 l(3)S023941c lethal (3) S023941c http://flybase.org/reports/FBgn0028186 gene - - - "0239/41, l(3)S023941, l(3)S023941c" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0011919 tRNA:Met-CAT-1-5 transfer RNA:Methionine-CAT 1-5 http://flybase.org/reports/FBgn0011919 "FBgn0051310, FBgn0060141" tRNA_gene AUG codon-amino acid adaptor activity ; GO:0033436 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033436 cytosol ; GO:0005829 | inferred by curator from GO:0033436 "Met-2, AE002699.trna7-MetCAT, tRNA:M:CAT:AE002699, CR31310, tRNA:met2:83F, tRNA[[e]][Met], chr3R.trna80-MetCAT, tRNA-Met[CAU], tRNA-Met-CAT-1-5, tRNA:Met-CAT-1-5, tRNA:M2:83F" - CR31310 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065261 l(2)SH2086 lethal (2) SH2086 http://flybase.org/reports/FBgn0065261 gene - - - "l(2)SH2086, l(2)SH2 2086" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0265915 asRNA:CR44704 - http://flybase.org/reports/FBgn0265915 non_protein_coding_gene - - - CR44704 - CR44704 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035611 CG13285 - http://flybase.org/reports/FBgn0035611 protein_coding_gene - - - "CG13285, FBgn0035611" - CG13285 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0259417 C926 - http://flybase.org/reports/FBgn0259417 gene - - - C926 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible wing vein FBgn0065286 l(2)SH2021 lethal (2) SH2021 http://flybase.org/reports/FBgn0065286 gene - - - "l(2)SH2021, l(2)SH2 2021" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0045050 fs(1)250 female sterile (1) 250 http://flybase.org/reports/FBgn0045050 gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(1)250 - - 27-Aug-18 DroID_v2018_08 - - - - - - female sterile "ovary,egg" FBgn0267676 asRNA:CR46012 - http://flybase.org/reports/FBgn0267676 non_protein_coding_gene - - - CR46012 - CR46012 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260766 CG42564 - http://flybase.org/reports/FBgn0260766 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern defense response to Gram-negative bacterium ; GO:0050829 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence model extracellular space ; GO:0005615 | inferred from direct assay extracellular region ; GO:0005576 | inferred from sequence model "CG42564, CG10284" "IPR014044:CAP domain, IPR001283:Cysteine-rich secretory protein, allergen V5/Tpx-1-related" CG42564 27-Aug-18 DroID_v2018_08 "Drer\crispld1a, Drer\r3hdml, Drer\crispld2, Drer\pi15a, Drer\glipr1b, Drer\crispld1b, Drer\glipr2l, Drer\glipr2, Drer\pi15b, Drer\LOC100536500" "Scer\PRY3, Scer\PRY2, Scer\PRY1" "Cele\scl-6, Cele\scl-1, Cele\scl-10, Cele\scl-23, Cele\scl-20, Cele\vap-2" "Xtro\MGC108118, Xtro\crisp1, Xtro\crispld2, Xtro\crisp2, Xtro\crisp3, Xtro\glipr2, Xtro\r3hdml" "Mmus\Crispld1, Mmus\Glipr1l2, Mmus\Clec18a, Mmus\Pi15, Mmus\Crisp2, Mmus\Crisp3, Mmus\Glipr1, Mmus\Crisp4, Mmus\Glipr1l1, Mmus\R3hdml, Mmus\Crisp1, Mmus\Crispld2, Mmus\Pi16, Mmus\Glipr2" "Hsap\GLIPR1, Hsap\PI15, Hsap\CRISP1, Hsap\CRISPLD1, Hsap\PI16, Hsap\CRISP2, Hsap\CLEC18C, Hsap\GLIPR1L2, Hsap\CRISPLD2, Hsap\R3HDML, Hsap\CLEC18A, Hsap\GLIPR1L1, Hsap\GLIPR2, Hsap\CLEC18B" viable FBgn0262904 asRNA:CR43259 - http://flybase.org/reports/FBgn0262904 non_protein_coding_gene - - - CR43259 - CR43259 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040679 CG11373 - http://flybase.org/reports/FBgn0040679 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG11373 - CG11373 27-Aug-18 DroID_v2018_08 - - - - - - "viable,body color defective" mesothoracic tergum FBgn0052625 CG32625 - http://flybase.org/reports/FBgn0052625 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32625 "IPR022776:TRM13/UPF0224 family, U11-48K-like CHHC zinc finger domain" CG32625 27-Aug-18 DroID_v2018_08 "Drer\zgc:56699, Drer\LOC100535654" - Cele\T06A10.3 Xtro\LOC100145274 "Mmus\BC048502, Mmus\Zfp850, Mmus\Gtsf1l, Mmus\Gtsf1" "Hsap\GTSF1, Hsap\GTSF1L" "viable,fertile" FBgn0065421 l(2)SH1522 lethal (2) SH1522 http://flybase.org/reports/FBgn0065421 gene - - - "l(2)SH1522, l(2)SH2 1522" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0082629 S(CycE[JP])2.9 S(CycE[JP])2.9 http://flybase.org/reports/FBgn0082629 gene - - - S(CycE[JP])2.9 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0040136 l(1)G0498 lethal (1) G0498 http://flybase.org/reports/FBgn0040136 gene - - - l(1)G0498 - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,male,female,lethal,recessive" FBgn0037702 CG8176 - http://flybase.org/reports/FBgn0037702 protein_coding_gene phospholipid binding ; GO:0005543 | inferred from sequence model AP-2 adaptor complex binding ; GO:0035612 | inferred from sequence or structural similarity with HGNC:29002 clathrin-dependent endocytosis ; GO:0072583 | inferred from sequence or structural similarity with HGNC:29002 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with HGNC:29002 clathrin-coated pit ; GO:0005905 | inferred from sequence or structural similarity with HGNC:29002 cytoplasm ; GO:0005737 | inferred from direct assay "CG31123, CG8176, FCHo2, FCHo" "IPR001060:FCH domain, IPR018808:Muniscin C-terminal, IPR028565:Mu homology domain, IPR027267:Arfaptin homology (AH) domain/BAR domain, IPR031160:F-BAR domain" CG8176 27-Aug-18 DroID_v2018_08 "Drer\pstpip2, Drer\sgip1a, Drer\pstpip1b, Drer\fcho1, Drer\gas7a, Drer\fcho2, Drer\pstpip1a, Drer\gas7b, Drer\sgip1b" "Scer\RGD2, Scer\HOF1" Cele\fcho-1 "Xtro\sgip1, Xtro\fcho1, Xtro\fcho2" "Mmus\Fcho2, Mmus\Pstpip2, Mmus\Gas7, Mmus\Sgip1, Mmus\Pstpip1, Mmus\Fcho1" "Hsap\PSTPIP2, Hsap\SGIP1, Hsap\FCHO2, Hsap\GAS7, Hsap\FCHO1, Hsap\PSTPIP1" "viable,fertile,visible" tormogen cell FBgn0035942 ValRS-m "Valyl-tRNA synthetase, mitochondrial" http://flybase.org/reports/FBgn0035942 protein_coding_gene "valine-tRNA ligase activity ; GO:0004832 | inferred from electronic annotation with InterPro:IPR002303 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001412, InterPro:IPR002300, InterPro:IPR002303, InterPro:IPR009080 aminoacyl-tRNA editing activity ; GO:0002161 | inferred from electronic annotation with InterPro:IPR009008 valine-tRNA ligase activity ; GO:0004832 | traceable author statement" valyl-tRNA aminoacylation ; GO:0006438 | inferred from electronic annotation with InterPro:IPR002303 valyl-tRNA aminoacylation ; GO:0006438 | traceable author statement mitochondrion ; GO:0005739 | traceable author statement "CG5660, ValRS-m" "IPR001412:Aminoacyl-tRNA synthetase, class I, conserved site, IPR002300:Aminoacyl-tRNA synthetase, class Ia, IPR002303:Valine-tRNA ligase, IPR009008:Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain, IPR009080:Aminoacyl-tRNA synthetase, class Ia, anticodon-binding, IPR013155:Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold, IPR033705:Valyl tRNA synthetase, anticodon-binding domain" CG5660 27-Aug-18 DroID_v2018_08 "Drer\vars, Drer\vars2" Scer\VAS1 "Cele\vars-1, Cele\glp-4" Xtro\vars2 "Mmus\Vars, Mmus\Vars2" "Hsap\VARS, Hsap\VARS2" "viable,visible" trichogen cell FBgn0011569 can cannonball http://flybase.org/reports/FBgn0011569 FBgn0036079 protein_coding_gene - spermatid differentiation ; GO:0048515 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:11539 inferred from sequence or structural similarity with HGNC:17304 inferred from sequence or structural similarity with SGD:S000000402 regulation of gene expression ; GO:0010468 | inferred from mutant phenotype spermatid development ; GO:0007286 | inferred from mutant phenotype male meiosis I ; GO:0007141 | inferred from mutant phenotype spermatid development ; GO:0007286 | traceable author statement meiotic nuclear division ; GO:0007126 | traceable author statement nucleolus ; GO:0005730 | inferred from direct assay male germ cell nucleus ; GO:0001673 | inferred from direct assay transcription factor TFIID complex ; GO:0005669 | inferred from sequence or structural similarity with HGNC:11539 inferred from sequence or structural similarity with HGNC:17304 inferred from sequence or structural similarity with SGD:S000000402 "dTAF5L, dTAF[[II]]80, dmTAF5b, TAF5L, CG6577, can, Can, Taf5L, WSB-1" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR007582:TFIID subunit TAF5, NTD2 domain, IPR017986:WD40-repeat-containing domain, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat" CG6577 27-Aug-18 DroID_v2018_08 "Drer\taf5l, Drer\taf5" Scer\TAF5 Cele\taf-5 "Xtro\taf5l, Xtro\taf5" "Mmus\Taf5, Mmus\Wdr38, Mmus\Taf5l" "Hsap\TAF5, Hsap\TAF5L" "male sterile,recessive,meiotic cell cycle defective,viable" "testis,spermatocyte" FBgn0260764 CG42562 - http://flybase.org/reports/FBgn0260764 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG14481, CG42562" - CG42562 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0259531 B2005 - http://flybase.org/reports/FBgn0259531 gene - - - B2005 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "leg,tarsal segment,tibia,arista" FBgn0052121 CG32121 - http://flybase.org/reports/FBgn0052121 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001135004 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001135004 CG32121 "IPR000210:BTB/POZ domain, IPR011333:SKP1/BTB/POZ domain, IPR013087:Zinc finger C2H2-type" CG32121 27-Aug-18 DroID_v2018_08 - - - - Mmus\Zbtb3 "Hsap\ZBTB12, Hsap\ZBTB24, Hsap\ZBTB9, Hsap\ZBTB49, Hsap\ZNF131" lethal FBgn0028883 CG4959 - http://flybase.org/reports/FBgn0028883 protein_coding_gene - - - "bs04e09.y1, BG:DS04095.3, BcDNA:GH21762, CG4959" - - 27-Aug-18 DroID_v2018_08 - - - - - - DRSC01938 K 0.787960895 0.540336643 -0.685209612 0.114267074 1.8736043 0.595796613 FBgn0030904 upd2 unpaired 2 http://flybase.org/reports/FBgn0030904 protein_coding_gene cytokine activity ; GO:0005125 | inferred from direct assay embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from electronic annotation with InterPro:IPR031901 intestinal epithelial structure maintenance ; GO:0060729 | inferred from mutant phenotype positive regulation of JAK-STAT cascade ; GO:0046427 | inferred from mutant phenotype positive regulation of JAK-STAT cascade ; GO:0046427 | inferred from direct assay inferred from genetic interaction with hop inferred from genetic interaction with Stat92E inferred from genetic interaction with Socs36E inferred from genetic interaction with dome inferred from genetic interaction with Ptp61F segment specification ; GO:0007379 | inferred from mutant phenotype positive regulation of JAK-STAT cascade ; GO:0046427 | inferred from direct assay positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype paracrine signaling ; GO:0038001 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay "Upd2, upd2, CG5988, cg5988, UPD2, Upd2/Leptin, Upd-like, upd, unpaired 2" IPR031901:Unpaired protein CG5988 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile,immune response defective,recessive,small body,decreased cell number,decreased cell size" "wing,embryonic/larval oenocyte" FBgn0266118 suffix\ORF - http://flybase.org/reports/FBgn0266118 transposable_element_gene - - - suffix\ORF - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0027084 LysRS Lysyl-tRNA synthetase http://flybase.org/reports/FBgn0027084 FBgn0030143 protein_coding_gene "lysine-tRNA ligase activity ; GO:0004824 | inferred from electronic annotation with InterPro:IPR002313, InterPro:IPR018149 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002313, InterPro:IPR004364, InterPro:IPR018149, InterPro:IPR018150 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR004365 lysine-tRNA ligase activity ; GO:0004824 | traceable author statement" "lysyl-tRNA aminoacylation ; GO:0006430 | inferred from electronic annotation with InterPro:IPR002313, InterPro:IPR018149 lysyl-tRNA aminoacylation ; GO:0006430 | traceable author statement" cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR018149 cytoplasm ; GO:0005737 | traceable author statement aminoacyl-tRNA synthetase multienzyme complex ; GO:0017101 | inferred from direct assay mitochondrion ; GO:0005739 | traceable author statement microtubule associated complex ; GO:0005875 | inferred from direct assay "LysRS, KRS, CG12141, Aats-lys" "IPR002313:Lysine-tRNA ligase, class II, IPR004364:Aminoacyl-tRNA synthetase, class II (D/K/N), IPR004365:OB-fold nucleic acid binding domain, AA-tRNA synthetase-type, IPR006195:Aminoacyl-tRNA synthetase, class II, IPR012340:Nucleic acid-binding, OB-fold, IPR018149:Lysyl-tRNA synthetase, class II, C-terminal, IPR034762:Bacterial/eukaryotic lysine-tRNA ligase, class II" CG12141 27-Aug-18 DroID_v2018_08 Drer\kars "Scer\KRS1, Scer\MSK1" Cele\kars-1 Xtro\kars Mmus\Kars Hsap\KARS embryonic stage "

ubiquitous , embryonic/larval salivary gland

" FBgn0266625 asRNA:CR45132 - http://flybase.org/reports/FBgn0266625 non_protein_coding_gene - - - CR45132 - CR45132 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0061103 l(3)S008702 lethal (3) S008702 http://flybase.org/reports/FBgn0061103 gene - - - "1004/09, 0947/13, 0737/04, 0680/02, 0087/02, l(3)S073704b, l(3)S094713, l(3)S100409b, l(3)S068002b, l(3)S008702b, l(3)S008702" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0083298 E(smoDN)1835 Enhancer of smoDN 1835 http://flybase.org/reports/FBgn0083298 gene - - - E(smoDN)1835 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001261 inaB inactivation no afterpotential B http://flybase.org/reports/FBgn0001261 - gene - - - inaB - - 27-Aug-18 DroID_v2018_08 - - - - - - "neurophysiology defective,visual behavior defective" "photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6" FBgn0014194 hyl hyl http://flybase.org/reports/FBgn0014194 - gene - - - hyl - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085702 CG41576 - http://flybase.org/reports/FBgn0085702 protein_coding_gene - - - CG41576 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0050418 nord nord http://flybase.org/reports/FBgn0050418 protein_coding_gene molecular_function ; GO:0003674 | no biological data available olfactory learning ; GO:0008355 | inferred from mutant phenotype learning or memory ; GO:0007611 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG3372, CG13574, CG30418, nord, E3272" "IPR003961:Fibronectin type III, IPR019326:Protein of unknown function DUF2369, IPR013783:Immunoglobulin-like fold" CG30418 27-Aug-18 DroID_v2018_08 "Drer\ndnfl, Drer\ndnf" - Cele\ndnf-1 Xtro\ndnf Mmus\Ndnf Hsap\NDNF "learning defective,memory defective,viable" FBgn0041130 l(2)45Af lethal (2) 45Af http://flybase.org/reports/FBgn0041130 gene - - - l(2)45Af - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0004096 l(2)60Dd lethal (2) 60Dd http://flybase.org/reports/FBgn0004096 - gene - - - l(2)60Dd - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0060462 l(3)S115510a lethal (3) S115510a http://flybase.org/reports/FBgn0060462 gene - - - l(3)S115510a - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0267965 lncRNA:CR46245 - http://flybase.org/reports/FBgn0267965 non_protein_coding_gene - - - "CR46245, Dm_X:36005" - CR46245 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0069445 E(br)444 E(br)444 http://flybase.org/reports/FBgn0069445 gene - - - E(br)444 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,visible,semidominant" leg FBgn0003191 ra rase http://flybase.org/reports/FBgn0003191 - gene - - - ra - - 27-Aug-18 DroID_v2018_08 - - - - - - viable "head bristle,scutellar bristle,macrochaeta,microchaeta,thorax,head" FBgn0034506 CG13870 - http://flybase.org/reports/FBgn0034506 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13870 - CG13870 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0039437 TwdlL TweedleL http://flybase.org/reports/FBgn0039437 protein_coding_gene structural constituent of chitin-based cuticle ; GO:0005214 | inferred from sequence or structural similarity with TwdlD chitin-based cuticle development ; GO:0040003 | inferred from sequence or structural similarity with TwdlD body morphogenesis ; GO:0010171 | inferred from sequence or structural similarity with TwdlD proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity with TwdlD "TwdlL, CG6447, TwdIL" IPR004145:Domain of unknown function DUF243 CG6447 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0022313 l(1)H22.1 lethal (1) H22.1 http://flybase.org/reports/FBgn0022313 - gene - - - "H22.1, l(1)H22.1" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0040742 CG15606 - http://flybase.org/reports/FBgn0040742 protein_coding_gene - - - CG15606 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031331 CG5440 - http://flybase.org/reports/FBgn0031331 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:12478 protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with HGNC:12478 cellular_component ; GO:0005575 | no biological data available CG5440 "IPR000608:Ubiquitin-conjugating enzyme E2, IPR016135:Ubiquitin-conjugating enzyme/RWD-like, IPR023313:Ubiquitin-conjugating enzyme, active site" CG5440 27-Aug-18 DroID_v2018_08 "Drer\ube2e1, Drer\ube2d3, Drer\ube2d1b, Drer\ube2d4, Drer\ube2d2, Drer\ube2t, Drer\ube2d1a, Drer\ube2e2, Drer\ube2e3, Drer\ube2na, Drer\ube2nb" "Scer\UBC4, Scer\PEX4, Scer\UBC13, Scer\UBC5" - "Xtro\ube2e3, Xtro\ube2d1, Xtro\ube2n, Xtro\ube2d4, Xtro\ube2d3, Xtro\ube2e1, Xtro\ube2e2" "Mmus\Ube2dnl2, Mmus\Ube2d1, Mmus\Ube2n, Mmus\Ube2d3, Mmus\Ube2d2b, Mmus\Ube2dnl1, Mmus\Ube2e3, Mmus\Ube2e1, Mmus\Ube2e2, Mmus\Ube2t" "Hsap\UBE2D4, Hsap\UBE2N, Hsap\UBE2E3, Hsap\UBE2D3, Hsap\UBE2D2, Hsap\UBE2E1, Hsap\UBE2D1, Hsap\UBE2Q2L, Hsap\UBE2E2, Hsap\UBE2T, Hsap\UBE2NL" FBgn0003277 RpII215 RNA polymerase II 215kD subunit http://flybase.org/reports/FBgn0003277 "FBgn0001616, FBgn0026704" protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR000684, InterPro:IPR000722, InterPro:IPR006592, InterPro:IPR007066, InterPro:IPR007073, InterPro:IPR007075, InterPro:IPR007080, InterPro:IPR007081, InterPro:IPR007083 RNA polymerase II activity ; GO:0001055 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000453465 DNA-directed RNA polymerase activity ; GO:0003899 | inferred from direct assay" mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs transcription from RNA polymerase II promoter ; GO:0006366 | inferred from sequence or structural similarity with HGNC:9187 inferred from sequence or structural similarity with SGD:S000002299 "polytene chromosome puff ; GO:0005703 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay DNA-directed RNA polymerase II, core complex ; GO:0005665 | inferred from sequence or structural similarity with HGNC:9187 inferred from sequence or structural similarity with SGD:S000002299 DNA-directed RNA polymerase II, core complex ; GO:0005665 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay" "Pol II, Pol II CTD, RNApol, CTD, Pol IIa, Pol IIo[ser2], Pol IIo[ser5], PolII, Rpb1, pol II, RNAP, RNAPII, 8WG16, RNAP II, H5, polII, dRPB1, RNA Pol II, POL, RNA pol II, CG1554, RNA polII, l(1)G0040, II, RPB1, RNAP II LS, RNApolII, RNA PolII, Ubl, Rpll215, 5, l(1)L5, L5, l(1)DF912, RpII, l(1)DC912, l(1)10Ca, RpII215, Pol IIo, RNAPII0, RNA pol IIo, Pol II[ser2], PolIIo, RNA PolI 215, Pol II0[ser5], Pol II0[ser2], Pol-IIa, RNA Pol II CTD, dRpb1, Pol IIo[Ser2], RPII215, RNApol2, Pol II Ser5P, IIo, Pol II Ser5p, rpII1, PolIIo[ser2], PolIIo[ser5], PolIIa, alphaPol IIo[ser2], RNA-PolII, Ser5-P Pol II, Poll II, Pol-II, RNA-Pol" "IPR000684:RNA polymerase II, heptapeptide repeat, eukaryotic, IPR000722:RNA polymerase, alpha subunit, IPR006592:RNA polymerase, N-terminal, IPR007066:RNA polymerase Rpb1, domain 3, IPR007073:RNA polymerase Rpb1, domain 7, IPR007075:RNA polymerase Rpb1, domain 6, IPR007080:RNA polymerase Rpb1, domain 1, IPR007081:RNA polymerase Rpb1, domain 5, IPR007083:RNA polymerase Rpb1, domain 4" CG1554 27-Aug-18 DroID_v2018_08 "Drer\polr2a, Drer\ubxn7, Drer\polr3a" "Scer\RPO21, Scer\RPO31" "Cele\ama-1, Cele\rpc-1" "Xtro\ubxn7, Xtro\polr3a" "Mmus\Polr3a, Mmus\Polr2a, Mmus\Ubxn7" "Hsap\UBXN7, Hsap\POLR2A, Hsap\SLC35G6, Hsap\POLR3A" "lethal,recessive,heat sensitive,viable,visible,dominant,fertile,lethal - all die before end of embryonic stage,some die during embryonic stage,chemical resistant,female sterile,cold sensitive,lethal - all die before end of larval stage,some die during larval stage,male fertile,partially,cell lethal,germline clone,male sterile,cell lethalcell lethal,somatic clone,lethal - all die before end of pupal stage,some die during pupal stage" "capitellum,ovariole,germline clone,oocyte,prothoracic tarsal segment 2,male,haltere" DRSC20280 EK -0.264436424 0.311638996 1.50902253 -2.929978114 1.809341559 5.322892763 FBgn0028243 l(3)S000721 lethal (3) S000721 http://flybase.org/reports/FBgn0028243 gene - - - "0007/21, l(3)S000721" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0000077 amx almondex http://flybase.org/reports/FBgn0000077 FBgn0028503 protein_coding_gene - mesoderm development ; GO:0007498 | inferred from mutant phenotype positive regulation of Notch signaling pathway ; GO:0045747 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype ectoderm development ; GO:0007398 | traceable author statement ectodermal cell fate determination ; GO:0001713 | inferred from mutant phenotype Notch receptor processing ; GO:0007220 | inferred from genetic interaction with N spanning component of plasma membrane ; GO:0044214 | inferred from sequence model "fs(1)amx, CG12127, BcDNA:GH02974, amx" IPR007829:TM2 domain CG12127 27-Aug-18 DroID_v2018_08 Drer\tm2d3 - "Cele\Y66D12A.21, Cele\C41D11.9" Xtro\tm2d3 "Mmus\Tm2d3, Mmus\Tm2d1" "Hsap\TM2D3, Hsap\TM2D1" "viable,fertile,lethal - all die before end of embryonic stage,neurogenic phenotype,some die during embryonic stage,visible,recessive,lethal,rescuable maternal effect,female sterile,maternal effect,lethal - all die before end of pupal stage,some die during pupal stage" "eye,epidermis,nervous system,ommatidium,thorax,rescuable maternal effect,ectoderm,embryonic epidermis,sensory mother cell,neuroblast,maternal effect,supernumerary" FBgn0000236 bu bulging http://flybase.org/reports/FBgn0000236 - gene - - - bu - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive,partially lethal - majority die" eye FBgn0020235 ATPsyngamma "ATP synthase, gamma subunit" http://flybase.org/reports/FBgn0020235 - protein_coding_gene "proton-transporting ATP synthase activity, rotational mechanism ; GO:0046933 | contributes_to inferred from sequence or structural similarity with SGD:S000000243" proton transport ; GO:0015992 | inferred from sequence or structural similarity with UniProtKB:P36542 ATP synthesis coupled proton transport ; GO:0015986 | inferred from sequence or structural similarity with SGD:S000000243 phagocytosis ; GO:0006909 | inferred from mutant phenotype "lipid particle ; GO:0005811 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) ; GO:0000275 | inferred from sequence or structural similarity with UniProtKB:P36542" "ATPsyn-gamma, CG7610, ATPsyn-gam, ATPG_DROME, ATPG, ATPsyngamma, ATP-syn-gamma" "IPR000131:ATP synthase, F1 complex, gamma subunit, IPR023632:ATP synthase, F1 complex, gamma subunit conserved site" CG7610 27-Aug-18 DroID_v2018_08 "Drer\taf3, Drer\atp5c1" Scer\ATP3 "Cele\Y69A2AR.18, Cele\taf-3" "Xtro\taf3, Xtro\atp5c1" "Mmus\Taf3, Mmus\Atp5c1" Hsap\ATP5C1 "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum DRSC14094 K -0.302446263 -0.192940616 -0.880534713 -1.005323255 1.829306441 1.573020866 FBgn0065703 l(2)SH0619 lethal (2) SH0619 http://flybase.org/reports/FBgn0065703 gene - - - "l(2)SH0619, l(2)SH2 0619" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0029606 CG14052 - http://flybase.org/reports/FBgn0029606 protein_coding_gene - - - CG14052 - CG14052 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" DRSC17907 I 2.181155943 -0.960851091 1.260429562 0.326207364 -0.084858147 0.354267025 FBgn0265756 lncRNA:CR44563 - http://flybase.org/reports/FBgn0265756 non_protein_coding_gene - - - "CR44563, lincRNA.588" - CR44563 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0023198 JmY Ju-myoY http://flybase.org/reports/FBgn0023198 - gene - - - "Jm Y, Y, JmY" - - 27-Aug-18 DroID_v2018_08 - - - - - - aging defective FBgn0085466 CG34437 - http://flybase.org/reports/FBgn0085466 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314" - "CG34437, CG16918, SPH201" "IPR001314:Peptidase S1A, chymotrypsin family, IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan" CG34437 27-Aug-18 DroID_v2018_08 - - "Cele\try-3, Cele\svh-1" - - "Hsap\PRTN3, Hsap\MASP1" FBgn0060455 l(3)S118608 lethal (3) S118608 http://flybase.org/reports/FBgn0060455 gene - - - "1186/08, l(3)S118608" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0040337 CG3021 - http://flybase.org/reports/FBgn0040337 protein_coding_gene sulfurtransferase activity ; GO:0016783 | inferred from electronic annotation with InterPro:IPR023382 tRNA wobble position uridine thiolation ; GO:0002143 | inferred from biological aspect of ancestor with PANTHER:PTN000232426 mitochondrial tRNA thio-modification ; GO:0070903 | inferred from biological aspect of ancestor with PANTHER:PTN000232429 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000232429 "EG:BACR7A4.8, anon-1Ed, E, CG3021" "IPR004506:tRNA-specific 2-thiouridylase, IPR023382:Adenine nucleotide alpha hydrolase-like domains, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold" CG3021 27-Aug-18 DroID_v2018_08 Drer\trmu Scer\SLM3 Cele\mttu-1 Xtro\trmu Mmus\Trmu Hsap\TRMU viable FBgn0003580 Su(sph) Suppressor of sparse hairs http://flybase.org/reports/FBgn0003580 - gene - - - "Su-x4, Su(sph)" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0015978 l(2)PC4-D lethal (2) PC4-D http://flybase.org/reports/FBgn0015978 - gene - - - l(2)PC4-D - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0026639 l(2)k10613 lethal (2) k10613 http://flybase.org/reports/FBgn0026639 - gene - - - l(2)k10613 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036652 CG13032 - http://flybase.org/reports/FBgn0036652 protein_coding_gene - - - CG13032 - CG13032 27-Aug-18 DroID_v2018_08 Drer\ccdc13 - - Xtro\ccdc13 Mmus\Ccdc13 Hsap\CCDC13 viable FBgn0040648 CG11666 - http://flybase.org/reports/FBgn0040648 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG11666 - CG11666 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0067348 l(3)95Ed lethal (3) 95Ed http://flybase.org/reports/FBgn0067348 gene - - - l(3)95Ed - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" "eye,somatic clone,wing margin,macrochaeta" FBgn0028578 pjc-16 pjc-16 http://flybase.org/reports/FBgn0028578 gene - - - pjc-16 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0050110 CG30110 - http://flybase.org/reports/FBgn0050110 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs09e07, CG30110" - CG30110 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC05686 I -1.529531705 -0.53450013 0.009128057 -0.174505015 -0.286136893 -0.310439807 FBgn0065362 l(2)SH1742 lethal (2) SH1742 http://flybase.org/reports/FBgn0065362 gene - - - "l(2)SH1742, l(2)SH2 1742" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0026679 IntS4 Integrator 4 http://flybase.org/reports/FBgn0026679 FBgn0030047 protein_coding_gene molecular_function ; GO:0003674 | no biological data available snRNA processing ; GO:0016180 | inferred from mutant phenotype snRNA processing ; GO:0016180 | inferred from sequence or structural similarity with HGNC:25048 neurogenesis ; GO:0022008 | inferred from mutant phenotype snRNA 3'-end processing ; GO:0034472 | inferred from direct assay integrator complex ; GO:0032039 | inferred from sequence or structural similarity with HGNC:25048 integrator complex ; GO:0032039 | inferred from biological aspect of ancestor with PANTHER:PTN000468509 "CG12113, IntS4, Int4, l(1)G0095" "IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical" CG12113 27-Aug-18 DroID_v2018_08 Drer\ints4 - Cele\W04A4.5 Xtro\ints4 Mmus\Ints4 Hsap\INTS4 "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0267464 asRNA:CR45814 - http://flybase.org/reports/FBgn0267464 non_protein_coding_gene - - - CR45814 - CR45814 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004663 ms(1)10A male sterile (1) 10A http://flybase.org/reports/FBgn0004663 "FBgn0002798, FBgn0002811" gene - - - "ms(1)BP6, ms(1)10A" - - 27-Aug-18 DroID_v2018_08 - - - - - - male sterile axoneme FBgn0003723 tonomacrochaetae tonomacrochaetae http://flybase.org/reports/FBgn0003723 - gene - - - "tmc, tonomacrochaetae" - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile,visible,recessive" "macrochaeta,adult abdomen" FBgn0267622 asRNA:CR45960 - http://flybase.org/reports/FBgn0267622 non_protein_coding_gene - - - CR45960 - CR45960 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264661 small-potatoes small potatoes http://flybase.org/reports/FBgn0264661 gene - "trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - small-potatoes - - 27-Aug-18 DroID_v2018_08 - - - - - - "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone,embryonic/larval dorsal trunk" FBgn0035996 CG3448 - http://flybase.org/reports/FBgn0035996 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR010585, InterPro:IPR014751" "DNA recombination ; GO:0006310 | inferred from electronic annotation with InterPro:IPR010585, InterPro:IPR014751 double-strand break repair ; GO:0006302 | inferred from electronic annotation with InterPro:IPR010585, InterPro:IPR014751" nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR010585 CG3448 IPR010585:DNA repair protein XRCC4 CG3448 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0015547 srg semirough http://flybase.org/reports/FBgn0015547 - gene - - - srg - - 27-Aug-18 DroID_v2018_08 - - - - - - visible eye FBgn0005729 l(1)TK205 lethal (1) TK205 http://flybase.org/reports/FBgn0005729 - gene - - - "l205, l(1)TK205" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0037181 CG11370 - http://flybase.org/reports/FBgn0037181 protein_coding_gene - - - CG11370 - CG11370 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" FBgn0259841 Su(Ste):CR42410 Su(Ste):CR42410 http://flybase.org/reports/FBgn0259841 non_protein_coding_gene - - - "Su(Ste):CR42410, CR42410" - CR42410 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001945 l(2)26Cf lethal (2) 26Cf http://flybase.org/reports/FBgn0001945 - gene - - - "l(2)gdh-13, l(2)26Cf" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0003420 slc slim chaetae http://flybase.org/reports/FBgn0003420 - gene - - - "l(1)3Ea, slc" - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile,visible" "macrochaeta,wing" FBgn0259457 EP-111 - http://flybase.org/reports/FBgn0259457 gene - - - EP-111 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing vein,wing,chaeta" FBgn0264342 CG43798 - http://flybase.org/reports/FBgn0264342 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43798, lincRNA.43" - CG43798 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0083011 snoRNA:Psi28S-1135b snoRNA:Psi28S-1135b http://flybase.org/reports/FBgn0083011 snoRNA_gene - - - "snoRNA:Psi28S-1135b, Psi28S-1135b, psi28S-1135b, CR34605" - CR34605 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000582 eq equational producer http://flybase.org/reports/FBgn0000582 - gene - - - eq - - 27-Aug-18 DroID_v2018_08 - - - - - - "meiotic cell cycle defective,male" FBgn0029980 CG10778 - http://flybase.org/reports/FBgn0029980 protein_coding_gene polyprenyltransferase activity ; GO:0002094 | inferred from biological aspect of ancestor with PANTHER:PTN000033324 phagocytosis ; GO:0006909 | inferred from mutant phenotype polyprenol biosynthetic process ; GO:0016094 | inferred from biological aspect of ancestor with PANTHER:PTN000033324 - CG10778 "IPR001441:Decaprenyl diphosphate synthase-like, IPR018520:Di-trans-poly-cis-decaprenylcistransferase-like, conserved site" CG10778 27-Aug-18 DroID_v2018_08 Drer\dhdds "Scer\RER2, Scer\SRT1" Cele\T01G1.4 Xtro\dhdds Mmus\Dhdds Hsap\DHDDS "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0003184 qf quetas finas http://flybase.org/reports/FBgn0003184 - gene - - - qf - - 27-Aug-18 DroID_v2018_08 - - - - - - "semi-sterile,viable" "microchaeta,macrochaeta" FBgn0039158 CG6182 - http://flybase.org/reports/FBgn0039158 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with Evi5 regulation of GTPase activity ; GO:0043087 | inferred from sequence or structural similarity with Evi5 - "BcDNA:LD17019, CG6182" IPR000195:Rab-GTPase-TBC domain CG6182 27-Aug-18 DroID_v2018_08 Drer\tbc1d7 - - Xtro\tbc1d7 Mmus\Tbc1d7 "Hsap\TBC1D7, Hsap\TBC1D7-LOC100130357" "viable,fertile" FBgn0031034 CG14205 - http://flybase.org/reports/FBgn0031034 protein_coding_gene "transferase activity, transferring acyl groups other than amino-acyl groups ; GO:0016747 | inferred from electronic annotation with InterPro:IPR002656" - - CG14205 "IPR002656:Acyltransferase 3, IPR006621:Nose resistant-to-fluoxetine protein, N-terminal" CG14205 27-Aug-18 DroID_v2018_08 Drer\oacyl - "Cele\oac-50, Cele\oac-14, Cele\oac-7, Cele\oac-20, Cele\oac-5, Cele\oac-9, Cele\oac-53, Cele\oac-46, Cele\oac-3, Cele\oac-31, Cele\nrf-6, Cele\oac-54, Cele\oac-32, Cele\oac-6, Cele\ndg-4, Cele\rhy-1, Cele\oac-55, Cele\oac-39" Xtro\LOC101732251 Mmus\Oacyl - viable FBgn0262358 CG43056 - http://flybase.org/reports/FBgn0262358 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43056 - CG43056 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032771 CG17349 - http://flybase.org/reports/FBgn0032771 protein_coding_gene G-protein coupled receptor binding ; GO:0001664 | inferred from sequence or structural similarity with HGNC:19152 negative regulation of cell death ; GO:0060548 | inferred from sequence or structural similarity with HGNC:19152 cytosol ; GO:0005829 | inferred from sequence or structural similarity with HGNC:19152 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:19152 "anon-WO0140519.204, CG17349" "IPR016024:Armadillo-type fold, IPR019399:Parkin co-regulated protein, IPR011989:Armadillo-like helical" CG17349 27-Aug-18 DroID_v2018_08 Drer\pacrg - Cele\E04F6.2 "Xtro\pacrgl, Xtro\pacrg" "Mmus\Pacrg, Mmus\Pacrgl" "Hsap\PACRGL, Hsap\PACRG" viable FBgn0019765 l(1)56 lethal (1) 56 http://flybase.org/reports/FBgn0019765 - gene - - - l(1)56 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0002875 Mu(f[3N]) Mutator of forked-3N http://flybase.org/reports/FBgn0002875 - gene - - - Mu(f[3N]) - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035110 thoc7 thoc7 http://flybase.org/reports/FBgn0035110 protein_coding_gene - mRNA processing ; GO:0006397 | inferred from electronic annotation with InterPro:IPR008501 mRNA export from nucleus in response to heat stress ; GO:0031990 | inferred by curator from GO:0000347 mRNA export from nucleus ; GO:0006406 | inferred from biological aspect of ancestor with PANTHER:PTN000381981 cell proliferation ; GO:0008283 | inferred from mutant phenotype response to heat ; GO:0009408 | inferred from mutant phenotype "THO complex part of transcription export complex ; GO:0000445 | inferred from biological aspect of ancestor with PANTHER:PTN000381981 THO complex ; GO:0000347 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay transcription export complex ; GO:0000346 | inferred from sequence or structural similarity with HGNC:29874 protein complex ; GO:0043234 | inferred from physical interaction with thoc5, Hpr1 chromosome, telomeric region ; GO:0000781 | inferred from biological aspect of ancestor with PANTHER:PTN000381981" "THOC7, CG17143, thoc7, Thoc7" IPR008501:THO complex subunit 7/Mft1 CG17143 27-Aug-18 DroID_v2018_08 Drer\thoc7 - Cele\B0513.2 Xtro\thoc7 Mmus\Thoc7 Hsap\THOC7 "viable,female fertile" FBgn0266155 lncRNA:CR44861 - http://flybase.org/reports/FBgn0266155 non_protein_coding_gene - - - CR44861 - CR44861 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0027843 CAH2 Carbonic anhydrase 2 http://flybase.org/reports/FBgn0027843 FBgn0036261 protein_coding_gene carbonate dehydratase activity ; GO:0004089 | inferred from direct assay one-carbon metabolic process ; GO:0006730 | inferred from direct assay intrinsic component of external side of plasma membrane ; GO:0031233 | inferred from sequence model "CG6906, CT21171, CAH2" "IPR001148:Alpha carbonic anhydrase, IPR023561:Carbonic anhydrase, alpha-class" CG6906 27-Aug-18 DroID_v2018_08 "Drer\ca4a, Drer\ca9, Drer\ca8, Drer\zgc:153760, Drer\si:ch211-173d10.4, Drer\ca6, Drer\car15, Drer\ca2, Drer\cahz, Drer\ca10a, Drer\ca12, Drer\ca15c, Drer\ca4b, Drer\ca7, Drer\ca10b, Drer\ca14, Drer\ca4c, Drer\ca15a, Drer\ca16b, Drer\ca5a, Drer\ptprga, Drer\ca15b" - "Cele\cah-3, Cele\cah-5, Cele\cah-6, Cele\cah-4" "Xtro\ca12, Xtro\ca7, Xtro\ca8, Xtro\ca10, Xtro\ca11, Xtro\ca2, Xtro\ca1, Xtro\ca3, Xtro\LOC779564, Xtro\ca4, Xtro\ca14, Xtro\ca5b, Xtro\ca6" "Mmus\Car10, Mmus\Car1, Mmus\Car5b, Mmus\Car2, Mmus\Car12, Mmus\Car4, Mmus\Car8, Mmus\Car11, Mmus\Car3, Mmus\Car6, Mmus\Car7, Mmus\Car13, Mmus\Car9, Mmus\Car15, Mmus\Ptprg, Mmus\Car14, Mmus\Car5a" "Hsap\CA9, Hsap\CA10, Hsap\CA1, Hsap\CA11, Hsap\CA5B, Hsap\CA12, Hsap\CA4, Hsap\CA2, Hsap\CA6, Hsap\CA7, Hsap\PTPRG, Hsap\CA3, Hsap\CA14, Hsap\CA5A, Hsap\CA8, Hsap\CA13" viable FBgn0001621 l(1)dh1 lethal (1) discs heterogeneous 1 http://flybase.org/reports/FBgn0001621 - gene - - - "l(1)d.het.-1, l(1)dh1" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" ventral thoracic disc FBgn0001245 hypoG hypoactive G http://flybase.org/reports/FBgn0001245 - gene - - - hypoG - - 27-Aug-18 DroID_v2018_08 - - - - - - "hypoactive,optomotor response defective,locomotor behavior defective,flight defective" FBgn0037082 CG5664 - http://flybase.org/reports/FBgn0037082 protein_coding_gene - - - CG5664 - CG5664 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0032020 strat stratum http://flybase.org/reports/FBgn0032020 protein_coding_gene guanyl-nucleotide exchange factor activity ; GO:0005085 | inferred from biological aspect of ancestor with PANTHER:PTN000328285 zinc ion binding ; GO:0008270 | inferred from sequence or structural similarity with UniProtKB:P47224 zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000328285 small GTPase mediated signal transduction ; GO:0007264 | inferred from electronic annotation with InterPro:IPR007515 post-Golgi vesicle-mediated transport ; GO:0006892 | inferred from biological aspect of ancestor with PANTHER:PTN000328285 membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN000328285 membrane ; GO:0016020 | inferred from sequence or structural similarity with SGD:S000006221 cytosol ; GO:0005829 | inferred from sequence or structural similarity with SGD:S000006221 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000328285 "BcDNA:RE45155, CG7787, Strat, strat" "IPR007515:Mss4, IPR011057:Mss4-like" CG7787 27-Aug-18 DroID_v2018_08 "Drer\rabif, Drer\lyplal1" Scer\DSS4 "Cele\mdt-9, Cele\ZK970.8" Xtro\rabif Mmus\Rabif Hsap\RABIF "partially lethal - majority die,some die during pupal stage" FBgn0015950 hsk helter-skelter http://flybase.org/reports/FBgn0015950 - gene - - - hsk - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,female sterile" embryonic/larval brain FBgn0028045 l(3)S097001 lethal (3) S097001 http://flybase.org/reports/FBgn0028045 gene - - - "1087/09, 1450/06, 0970/01, l(3)S108709, l(3)S097001" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die" FBgn0069149 mcl(3)Z3426 mcl(3)Z3426 http://flybase.org/reports/FBgn0069149 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z3426 - - 27-Aug-18 DroID_v2018_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0033712 mIF3 mitochondrial translation initiation factor 3 http://flybase.org/reports/FBgn0033712 protein_coding_gene "ribosomal small subunit binding ; GO:0043024 | inferred from sequence or structural similarity with UniProtKB:Q9H2K0 translation factor activity, RNA binding ; GO:0008135 | inferred from sequence or structural similarity with UniProtKB:Q9H2K0 translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity with SGD:S000003667" ribosome disassembly ; GO:0032790 | inferred from sequence or structural similarity with UniProtKB:Q9H2K0 mitochondrial translational initiation ; GO:0070124 | inferred from sequence or structural similarity with UniProtKB:Q9H2K0 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with SGD:S000003667 mitochondrion ; GO:0005739 | traceable author statement "CG13163, mIF3" "IPR001288:Translation initiation factor 3, IPR019815:Translation initiation factor 3, C-terminal" CG13163 27-Aug-18 DroID_v2018_08 Drer\mtif3 - - - Mmus\Mtif3 Hsap\MTIF3 viable FBgn0028611 l(2)W14 lethal (2) W14 http://flybase.org/reports/FBgn0028611 gene - - - "l(2R)W14, l(2)W14" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0053736 snmRNA:430j snmRNA:430:CR33736 http://flybase.org/reports/FBgn0053736 non_protein_coding_gene - - - "CR33736, snmRNA:430:CR33736" - CR33736 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263240 Coop Corepressor of Pangolin http://flybase.org/reports/FBgn0263240 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR004210 transcription factor binding ; GO:0008134 | inferred from physical interaction with pan RNA polymerase II transcription corepressor activity ; GO:0001106 | inferred from direct assay negative regulation of Wnt signaling pathway ; GO:0030178 | inferred from direct assay negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay transcription factor complex ; GO:0005667 | inferred from physical interaction with pan nucleus ; GO:0005634 | inferred from direct assay "CG1621, Coop, coop" "IPR004210:BESS motif, IPR006578:MADF domain" CG1621 27-Aug-18 DroID_v2018_08 "Drer\zgc:152938, Drer\si:ch211-207i20.3, Drer\LOC100330838" - "Cele\madf-10, Cele\madf-4, Cele\madf-8, Cele\madf-9, Cele\madf-3, Cele\madf-2, Cele\madf-5" - - - FBgn0001255 ImpE3 Ecdysone-inducible gene E3 http://flybase.org/reports/FBgn0001255 "FBgn0037542, FBgn0040525" protein_coding_gene - imaginal disc eversion ; GO:0007561 | traceable author statement plasma membrane ; GO:0005886 | inferred from sequence or structural similarity extrinsic component of membrane ; GO:0019898 | traceable author statement "CG2723, CG11046, Imp-E3, IMP-E3, ImpE3" - CG2723 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" DRSC16716 IE 1.217114555 2.211865468 -0.711556829 1.843291439 0.066562464 0.954554432 FBgn0069441 E(zip)18-5 E(zip)18-5 http://flybase.org/reports/FBgn0069441 gene - - - "18-5, E(zip)18-5" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0260283 GSd322 - http://flybase.org/reports/FBgn0260283 gene - - - GSd322 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0033990 CG10265 - http://flybase.org/reports/FBgn0033990 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available "CG30474, CG10265" - CG10265 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC05986 E -0.442621924 -0.052328941 0.469293004 1.514876172 -0.362199737 -0.51456077 FBgn0020369 Rpt6 Regulatory particle triple-A ATPase 6 http://flybase.org/reports/FBgn0020369 FBgn0023422 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959, InterPro:IPR003960 TBP-class protein binding ; GO:0017025 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 ATPase activity ; GO:0016887 | inferred from sequence model proteasome-activating ATPase activity ; GO:0036402 | inferred from biological aspect of ancestor with PANTHER:PTN000553036" proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from mutant phenotype ER-associated ubiquitin-dependent protein catabolic process ; GO:0030433 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred by curator from GO:0005838 cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ; GO:0045899 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 "proteasome regulatory particle, base subcomplex ; GO:0008540 | inferred from sequence or structural similarity with SGD:S000003016 proteasome regulatory particle ; GO:0005838 | inferred from sequence or structural similarity with HGNC:9552 inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay proteasome regulatory particle ; GO:0005838 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay proteasome regulatory particle, base subcomplex ; GO:0008540 | inferred from direct assay nuclear proteasome complex ; GO:0031595 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 cytosolic proteasome complex ; GO:0031597 | inferred from biological aspect of ancestor with PANTHER:PTN000553036" "p42C, dRpt6, Dm_Rpt6a, DUG, pros45, sug1, sug-1, Ug, Dug, CG1489, Rpt6, 1489, PRS8_DROME, S8, Pros45" "IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR003960:ATPase, AAA-type, conserved site, IPR005937:26S proteasome subunit P45, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG1489 27-Aug-18 DroID_v2018_08 "Drer\psmc5, Drer\psmc6, Drer\wdr12, Drer\psmc2" Scer\RPT6 "Cele\rpt-4, Cele\C10G11.8, Cele\rpt-6, Cele\F56F11.4" "Xtro\psmc6, Xtro\psmc2, Xtro\wdr12, Xtro\psmc5" "Mmus\Wdr12, Mmus\Psmc2, Mmus\Psmc6, Mmus\Psmc5" "Hsap\PSMC6, Hsap\WDR12, Hsap\PSMC2, Hsap\PSMC5" " embryonic stage | stage 13 , embryonic stage | stage 16 , adult stage | male , embryonic stage--pupal stage , larval stage | first instar , embryonic stage | early , adult stage | female , embryonic stage " " posterior midgut proper primordium

, embryonic central nervous system

, anterior midgut proper primordium

, larval nervous system

,

ubiquitous , pole cell | stage 5-8

" embryonic stage -- adult stage "viable,fertile,lethal,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0069419 JJF106 JJF106 http://flybase.org/reports/FBgn0069419 gene - - - JJF106 - - 27-Aug-18 DroID_v2018_08 - - - - - - stress response defective FBgn0031333 CG5561 - http://flybase.org/reports/FBgn0031333 protein_coding_gene phosphatase activity ; GO:0016791 | inferred from biological aspect of ancestor with PANTHER:PTN000431248 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR006439 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000431248 CG5561 "IPR023198:Phosphoglycolate phosphatase, domain 2, IPR006439:HAD hydrolase, subfamily IA, IPR023214:HAD-like domain" CG5561 27-Aug-18 DroID_v2018_08 Drer\pudp "Scer\YKL033W-A, Scer\GPP1, Scer\DOG2, Scer\GPP2, Scer\DOG1" Cele\R151.10 Xtro\pudp Mmus\Hdhd1a Hsap\PUDP "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0004528 l(4)102ABe lethal (4) 102ABe http://flybase.org/reports/FBgn0004528 - gene - - - "l(4)18, l(4)35, l(4)102ABe" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,some die during immature adult stage" FBgn0267569 asRNA:CR45909 - http://flybase.org/reports/FBgn0267569 non_protein_coding_gene - - - CR45909 - CR45909 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000519 dwf dwarfoid http://flybase.org/reports/FBgn0000519 - gene - - - dwf - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,viable,reduced,male fertile,female fertile,female sterile,recessive,poor" "adult abdomen,adult thorax" FBgn0029513 Abd-B-PTS Abdominal B promoter targeting sequence http://flybase.org/reports/FBgn0029513 regulatory_region - - - "PTS-7, PTS, Abd-B-PTS" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0003259 Rm2 Ring magnifier on 2 http://flybase.org/reports/FBgn0003259 - gene - - - Rm2 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032372 CG4988 - http://flybase.org/reports/FBgn0032372 protein_coding_gene "carbohydrate binding ; GO:0030246 | inferred from electronic annotation with InterPro:IPR011013, InterPro:IPR014718 aldose 1-epimerase activity ; GO:0004034 | inferred from biological aspect of ancestor with PANTHER:PTN000009552" galactose catabolic process via UDP-galactose ; GO:0033499 | inferred from biological aspect of ancestor with PANTHER:PTN000009552 glucose metabolic process ; GO:0006006 | inferred from biological aspect of ancestor with PANTHER:PTN000009552 - CG4988 "IPR008183:Aldose 1-/Glucose-6-phosphate 1-epimerase, IPR011013:Galactose mutarotase-like domain, IPR014718:Glycoside hydrolase-type carbohydrate-binding, IPR015443:Aldose 1-epimerase" CG4988 27-Aug-18 DroID_v2018_08 "Drer\galm, Drer\lfng, Drer\rfng, Drer\mfng" "Scer\GAL10, Scer\YNR071C, Scer\YHR210C" "Cele\Y19D10A.16, Cele\C01B4.6" "Xtro\galm, Xtro\rfng, Xtro\lfng" "Mmus\Galm, Mmus\Lfng, Mmus\Mfng, Mmus\Rfng" "Hsap\LFNG, Hsap\GALM, Hsap\MFNG, Hsap\RFNG" FBgn0033880 CG6553 - http://flybase.org/reports/FBgn0033880 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - CG6553 "IPR000436:Sushi/SCR/CCP domain, IPR002172:Low-density lipoprotein (LDL) receptor class A repeat, IPR023415:Low-density lipoprotein (LDL) receptor class A, conserved site" CG6553 27-Aug-18 DroID_v2018_08 "Drer\ldlra, Drer\scospondin, Drer\lrp3, Drer\lrp8, Drer\lrp12, Drer\lrp1bb, Drer\lrp1ba, Drer\lrp10, Drer\LOC100536757, Drer\ldlrad3, Drer\si:dkey-258f14.3, Drer\sorl1, Drer\lrp1ab" "Scer\APM3, Scer\APM2, Scer\APM1" "Cele\rme-2, Cele\F32E10.8, Cele\M03E7.4, Cele\F09B12.5" "Xtro\lrp12, Xtro\lrp2, Xtro\sorl1, Xtro\lrp4, Xtro\lrp10, Xtro\lrp1" "Mmus\Lrp4, Mmus\Ldlrad1, Mmus\Cd320, Mmus\Lrp10, Mmus\Lrp1b, Mmus\LOC102637808, Mmus\Lrp3, Mmus\Lrp1, Mmus\Lrp2, Mmus\Sspo, Mmus\Lrp12, Mmus\Sorl1" "Hsap\LRP3, Hsap\LRP1, Hsap\LRP4, Hsap\LRP5L, Hsap\SORL1, Hsap\CD320, Hsap\LDLRAD1, Hsap\LRP1B, Hsap\LRP10, Hsap\LRP12, Hsap\LRP2" viable FBgn0040268 Top3alpha Topoisomerase 3alpha http://flybase.org/reports/FBgn0040268 protein_coding_gene "DNA topoisomerase type I activity ; GO:0003917 | inferred from electronic annotation with InterPro:IPR000380, InterPro:IPR023406 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR000380, InterPro:IPR003601, InterPro:IPR003602, InterPro:IPR013497, InterPro:IPR013498 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001878, InterPro:IPR010666 DNA topoisomerase activity ; GO:0003916 | inferred from direct assay" "DNA topological change ; GO:0006265 | inferred from electronic annotation with InterPro:IPR000380, InterPro:IPR003601, InterPro:IPR003602, InterPro:IPR013497, InterPro:IPR013498 mitochondrial genome maintenance ; GO:0000002 | inferred from mutant phenotype developmental growth ; GO:0048589 | inferred from mutant phenotype tissue regeneration ; GO:0042246 | inferred from mutant phenotype double-strand break repair via homologous recombination ; GO:0000724 | inferred from mutant phenotype" chromosome ; GO:0005694 | inferred from electronic annotation with InterPro:IPR013498 mitochondrion ; GO:0005739 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "DmTop3alpha, Top3a, dTopoIIIa, CG10123, Top3alpha, Topo IIIalpha, top3alpha, topo IIIalpha" "IPR000380:DNA topoisomerase, type IA, IPR003601:DNA topoisomerase, type IA, domain 2, IPR003602:DNA topoisomerase, type IA, DNA-binding domain, IPR006171:TOPRIM domain, IPR013497:DNA topoisomerase, type IA, central, IPR013498:DNA topoisomerase, type IA, zn finger, IPR023405:DNA topoisomerase, type IA, core domain, IPR023406:DNA topoisomerase, type IA, active site, IPR034144:DNA topoisomerase 3-like, TOPRIM domain, IPR013825:DNA topoisomerase, type IA, central region, subdomain 2, IPR010666:Zinc finger, GRF-type" CG10123 27-Aug-18 DroID_v2018_08 Drer\top3a Scer\TOP3 Cele\top-3 "Xtro\top3b, Xtro\top3a" "Mmus\Top3b, Mmus\Top3a" "Hsap\TOP3B, Hsap\TOP3A" "visible,conditional,size defective,female sterile,male sterile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,developmental rate defective,lethal - all die before end of prepupal stage,recessive,some die during prepupal stage,viable,lethal,melanotic necrosis" "eye,conditional,egg,maternal effect,testis,sperm individualization complex, with Top3ë±54,imaginal disc,sperm individualization complex, with Top3ë±M1L.TAvicGFP-EYFP,melanotic mass" FBgn0032362 spz4 spatzle 4 http://flybase.org/reports/FBgn0032362 protein_coding_gene Toll binding ; GO:0005121 | inferred from sequence or structural similarity with spz Toll signaling pathway ; GO:0008063 | inferred from sequence or structural similarity with spz extracellular region ; GO:0005576 | inferred from sequence or structural similarity with spz "CG14928, Spz4, spz4, CT34755" "IPR029034:Cystine-knot cytokine, IPR032104:Spaetzle" CG14928 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC02410 IE 1.088307464 1.509271305 2.088802389 -1.519118626 0.195574073 0.08780924 FBgn0085756 CR40613 - http://flybase.org/reports/FBgn0085756 rRNA_gene - - - CR40613 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267939 lncRNA:CR46219 - http://flybase.org/reports/FBgn0267939 non_protein_coding_gene - - - "CR46219, lincRNA.903" - CR46219 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259282 C37 - http://flybase.org/reports/FBgn0259282 gene - - - C37 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing,wing margin,chaeta" FBgn0063781 accord2\gag accord2 element gag http://flybase.org/reports/FBgn0063781 transposable_element_gene - - - "qbert\gag, accord2\gag" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005104 gusC gustatory C http://flybase.org/reports/FBgn0005104 - gene molecular_function ; GO:0003674 | no biological data available larval feeding behavior ; GO:0030536 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available gusC - - 27-Aug-18 DroID_v2018_08 - - - - - - taste perception defective FBgn0266384 asRNA:CR45026 - http://flybase.org/reports/FBgn0266384 non_protein_coding_gene - - - CR45026 - CR45026 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260103 2L0372 - http://flybase.org/reports/FBgn0260103 gene - "lumen formation, open tracheal system ; GO:0035149 | inferred from mutant phenotype" - 2L0372 - - 27-Aug-18 DroID_v2018_08 - - - - - - "embryonic/larval dorsal trunk,somatic clone" FBgn0051346 CG31346 - http://flybase.org/reports/FBgn0051346 protein_coding_gene - - - CG31346 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065410 l(2)SH1570 lethal (2) SH1570 http://flybase.org/reports/FBgn0065410 gene - - - "l(2)SH1570, l(2)SH2 1570" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0086170 nkd::Hsap\NKD2 - http://flybase.org/reports/FBgn0086170 engineered_fusion_gene - - - nkd::Hsap\NKD2 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0086210 su(comp)3L-2 - http://flybase.org/reports/FBgn0086210 gene - - - su(comp)3L-2 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038541 TyrRII Tyramine receptor II http://flybase.org/reports/FBgn0038541 protein_coding_gene G-protein coupled amine receptor activity ; GO:0008227 | inferred from sequence or structural similarity G-protein coupled amine receptor activity ; GO:0008227 | inferred from direct assay G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity tyramine signaling pathway ; GO:0071928 | inferred from direct assay cellular response to amine stimulus ; GO:0071418 | inferred from direct assay adenylate cyclase-activating dopamine receptor signaling pathway ; GO:0007191 | inferred from biological aspect of ancestor with PANTHER:PTN000665343 phospholipase C-activating dopamine receptor signaling pathway ; GO:0060158 | inferred from biological aspect of ancestor with PANTHER:PTN000665343 learning ; GO:0007612 | inferred from biological aspect of ancestor with PANTHER:PTN000665343 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway ; GO:0007193 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "DmCG16766, anon-WO0170980.125, anon-WO0170980.124, TyrRII, CG16766" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG16766 27-Aug-18 DroID_v2018_08 "Drer\drd7, Drer\drd4b, Drer\drd6b, Drer\drd1b, Drer\LOC563567, Drer\drd2a, Drer\hrh2b, Drer\drd2l, Drer\si:dkey-247m21.3, Drer\drd3, Drer\htr4, Drer\LOC567498, Drer\drd4-rs, Drer\drd2b, Drer\drd4a, Drer\drd1a" - Cele\tyra-3 "Xtro\htr4, Xtro\drd2" "Mmus\Drd4, Mmus\Htr4, Mmus\Adra1d, Mmus\Ptger4, Mmus\Drd5, Mmus\Drd1, Mmus\Drd3, Mmus\Drd2, Mmus\Hrh2" "Hsap\DRD4, Hsap\ADRA1D, Hsap\DRD1, Hsap\HTR4, Hsap\HRH2, Hsap\PTGER4, Hsap\DRD2, Hsap\DRD5, Hsap\DRD3" FBgn0010014 CanB Calcineurin B http://flybase.org/reports/FBgn0010014 "FBgn0004466, FBgn0029757, FBgn0047037" protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 calcium-dependent protein serine/threonine phosphatase regulator activity ; GO:0008597 | inferred from sequence or structural similarity calmodulin binding ; GO:0005516 | inferred from sequence or structural similarity calcium ion binding ; GO:0005509 | inferred from sequence or structural similarity positive regulation of NFAT protein import into nucleus ; GO:0051533 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from direct assay neurotransmitter secretion ; GO:0007269 | non-traceable author statement vesicle-mediated transport ; GO:0016192 | non-traceable author statement protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype calcineurin complex ; GO:0005955 | inferred from sequence or structural similarity synaptic vesicle ; GO:0008021 | non-traceable author statement "Calcineurin B, canB-4F, CNB, dCnB1, BcDNA:RH11383, Can, CG4209, CanB, CnB, CaNB" "IPR002048:EF-hand domain, IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site" CG4209 27-Aug-18 DroID_v2018_08 "Drer\chp1, Drer\LOC100536377, Drer\tescb, Drer\chp2, Drer\wdr92, Drer\ppp3r1b, Drer\tesca, Drer\ppp3r1a" Scer\CNB1 Cele\cnb-1 "Xtro\chp1, Xtro\wdr92, Xtro\ppp3r1, Xtro\cib1" "Mmus\Chp1, Mmus\Chp2, Mmus\Ppp3r2, Mmus\Tescl, Mmus\Cib1, Mmus\Tesc, Mmus\Wdr92, Mmus\Ppp3r1, Mmus\Cib4" "Hsap\CIB1, Hsap\CHP2, Hsap\PPP3R1, Hsap\CIB4, Hsap\WDR92, Hsap\TESC, Hsap\CHP1, Hsap\PPP3R2" embryonic stage "viable,fertile,wild-type,sleep defective,locomotor behavior defective" FBgn0267992 lncRNA:CR46259 - http://flybase.org/reports/FBgn0267992 non_protein_coding_gene - - - CR46259 - CR46259 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038448 CG12783 - http://flybase.org/reports/FBgn0038448 protein_coding_gene substrate-specific transmembrane transporter activity ; GO:0022891 | inferred from biological aspect of ancestor with PANTHER:PTN000756324 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005828 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000756324 CG12783 "IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG12783 27-Aug-18 DroID_v2018_08 "Drer\slc22a13, Drer\LOC101884074, Drer\slc22a7b.1, Drer\LOC100334012, Drer\slc22a6l, Drer\slc22a7b.2, Drer\svopa, Drer\slc22a21, Drer\slc22a7b.3, Drer\sv2, Drer\sv2ba, Drer\sv2bb, Drer\svopl, Drer\sv2c, Drer\slc22a5, Drer\sv2a, Drer\zgc:175176, Drer\zmp:0000001102, Drer\svopb, Drer\oatx" "Scer\FLR1, Scer\TPO1, Scer\QDR3, Scer\TPO3, Scer\DTR1, Scer\QDR2, Scer\AQR1, Scer\QDR1, Scer\YHK8, Scer\TPO2" Cele\svop-1 "Xtro\sv2b, Xtro\slc22a6" "Mmus\Slc22a28, Mmus\Slc22a2, Mmus\Sv2c, Mmus\Svop, Mmus\Slc22a20, Mmus\Slc22a23, Mmus\Slc22a6, Mmus\Sv2a, Mmus\Slc22a22, Mmus\Slc22a19, Mmus\Slc22a30, Mmus\Slc22a7, Mmus\Slc22a29, Mmus\Sv2b, Mmus\Svopl, Mmus\Slc22a8, Mmus\Slc22a27, Mmus\Slc22a16, Mmus\Slc22a4, Mmus\Slc22a26, Mmus\Slc22a14" "Hsap\SVOPL, Hsap\SV2C, Hsap\SLC22A2, Hsap\SLC22A25, Hsap\SLC22A11, Hsap\SLC22A23, Hsap\SLC22A9, Hsap\SVOP, Hsap\SLC22A10, Hsap\SLC22A24, Hsap\SLC22A8, Hsap\SV2A, Hsap\SLC22A7, Hsap\SLC22A6, Hsap\SLC22A12, Hsap\SLC22A1, Hsap\SV2B" "viable,fertile" FBgn0024871 l(2)k09033 lethal (2) k09033 http://flybase.org/reports/FBgn0024871 - gene - - - l(2)k09033 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0024722 Su(var)57D58D Su(var)57D58D http://flybase.org/reports/FBgn0024722 - gene - - - Su(var)57D58D - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267971 Ir52e Ionotropic receptor 52e http://flybase.org/reports/FBgn0267971 protein_coding_gene - - - "Ir52e, IR52e" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033609 Fbl6 F-box and leucine-rich repeat protein 6 http://flybase.org/reports/FBgn0033609 protein_coding_gene SAM domain binding ; GO:0032093 | inferred from physical interaction with aop ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model regulation of protein stability ; GO:0031647 | inferred from direct assay positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:2000060 | inferred from direct assay SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model nucleoplasm ; GO:0005654 | inferred from sequence or structural similarity with HGNC:13603 "Fbl6, CG13213, FBXL6, fbl6" "IPR001810:F-box domain, IPR001611:Leucine-rich repeat, IPR032675:Leucine-rich repeat domain, L domain-like, IPR006553:Leucine-rich repeat, cysteine-containing subtype" CG13213 27-Aug-18 DroID_v2018_08 "Drer\fbxl15, Drer\kdm2aa, Drer\kdm2ab, Drer\zgc:158376, Drer\fbxl6, Drer\si:dkey-192l18.9, Drer\fbxl17, Drer\fbxl4" Scer\GRR1 - "Xtro\fbxl12, Xtro\kdm2b, Xtro\fbxl4, Xtro\fbxl19" "Mmus\Fbxl17, Mmus\Lrrc29, Mmus\Kdm2b, Mmus\Fbxl21, Mmus\Fbxl6, Mmus\Fbxl19, Mmus\Fbxl4, Mmus\Kdm2a" "Hsap\FBXL19, Hsap\LRRC29, Hsap\KDM2A, Hsap\FBXL4, Hsap\KDM2B, Hsap\FBXL17, Hsap\FBXL6" "visible,partially lethal - majority die,some die during pupal stage,viable,fertile" "trichogen cell,mesothoracic tergum" DRSC06335 I -1.556861459 0.621255344 0.942042203 0.1390746 -0.582396972 0.65945824 FBgn0061161 l(1)7Bg lethal (1) 7Bg http://flybase.org/reports/FBgn0061161 gene - - - l(1)7Bg - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0020318 anon-86Fa anon-86Fa http://flybase.org/reports/FBgn0020318 - gene - - - "1D10, anon-86Fa" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000029 AcpB Accessory gland protein B http://flybase.org/reports/FBgn0000029 - gene - - - AcpB - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000945 fs(2)A15 female sterile (2) A15 http://flybase.org/reports/FBgn0000945 - gene - - - fs(2)A15 - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive" "ovary,oocyte" FBgn0040353 CG14417 - http://flybase.org/reports/FBgn0040353 protein_coding_gene - - - "EG:BACR43E12.6, CG14417" - CG14417 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0000767 fs(1)A1024 female sterile (1) A1024 http://flybase.org/reports/FBgn0000767 - gene - - - fs(1)A1024 - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive,lethal - all die before end of pupal stage,rescuable maternal effect,some die during pupal stage" wing FBgn0034730 ppk12 pickpocket 12 http://flybase.org/reports/FBgn0034730 protein_coding_gene sodium channel activity ; GO:0005272 | inferred from sequence or structural similarity with MGI:MGI:101782 sodium ion transport ; GO:0006814 | inferred from sequence or structural similarity with MGI:MGI:101782 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with MGI:MGI:101782 "CG10972, PPK12, ppk12" IPR001873:Epithelial sodium channel CG10972 27-Aug-18 DroID_v2018_08 "Drer\smarcd3b, Drer\asic4b, Drer\asic4a, Drer\asic1b, Drer\asic1a, Drer\smarcd3a, Drer\asic2, Drer\asic1c, Drer\smarcd1" "Scer\RSC6, Scer\SNF12" "Cele\asic-2, Cele\acd-1, Cele\delm-1, Cele\acd-4, Cele\acd-3, Cele\flr-1, Cele\acd-2, Cele\delm-2, Cele\ham-3, Cele\mec-10, Cele\del-7, Cele\asic-1, Cele\del-4, Cele\swsn-2.2, Cele\acd-5, Cele\del-8, Cele\del-6" "Xtro\scnn1b, Xtro\scnn1g, Xtro\scnn1a, Xtro\asic1, Xtro\scnn1d, Xtro\asic5, Xtro\asic4" "Mmus\Asic1, Mmus\Scnn1a, Mmus\Asic4, Mmus\Scnn1b, Mmus\Asic3, Mmus\Scnn1g, Mmus\Asic5, Mmus\Smarcd3, Mmus\Smarcd1, Mmus\Smarcd2, Mmus\Asic2" "Hsap\ASIC3, Hsap\ASIC1, Hsap\SMARCD2, Hsap\ASIC5, Hsap\SMARCD1, Hsap\ASIC2, Hsap\SCNN1A, Hsap\ASIC4, Hsap\SCNN1B, Hsap\SCNN1G, Hsap\SMARCD3, Hsap\SCNN1D" viable DRSC04086 I -0.497343513 -1.795308451 -0.956148973 0.645294904 0.25377 -0.702192321 FBgn0067751 l(1)G0189 lethal (1) G0189 http://flybase.org/reports/FBgn0067751 gene - - - l(1)G0189 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0083009 snoRNA:Psi28S-1135d snoRNA:Psi28S-1135d http://flybase.org/reports/FBgn0083009 snoRNA_gene - - - "snoRNA:Psi28S-1135d, Psi28S-1135d, psi28S-1135d, CR34603" - CR34603 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0019798 l(1)07 lethal (1) 07 http://flybase.org/reports/FBgn0019798 - gene - - - l(1)07 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0015263 Mst23Ea Male-specific transcript 23Ea http://flybase.org/reports/FBgn0015263 - gene - - - Mst23Ea - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0083085 kur kur http://flybase.org/reports/FBgn0083085 gene - - - "kurzkern, kur" - - 27-Aug-18 DroID_v2018_08 - - - - - - "nucleus | gastrula stage,nucleus | blastoderm stage" FBgn0267759 lncRNA:CR46090 - http://flybase.org/reports/FBgn0267759 non_protein_coding_gene - - - CR46090 - CR46090 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038414 CG6901 - http://flybase.org/reports/FBgn0038414 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from electronic annotation with InterPro:IPR005828 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005828 sensory perception of pain ; GO:0019233 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005828 CG6901 "IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG6901 27-Aug-18 DroID_v2018_08 "Drer\slc2a6, Drer\slc2a10, Drer\slc2a13b, Drer\slc2a8, Drer\LOC101882338, Drer\slc2a12" "Scer\GEX2, Scer\SNF3, Scer\HXT5, Scer\GEX1, Scer\ATR1, Scer\GAL2, Scer\ENB1, Scer\YMR279C, Scer\HXT2, Scer\ITR1, Scer\HXT13, Scer\MAL11, Scer\SGE1, Scer\YDR387C, Scer\YFL040W, Scer\VBA1, Scer\MAL31, Scer\RGT2, Scer\HXT15, Scer\HXT11, Scer\HXT1, Scer\HXT17, Scer\HXT3, Scer\HXT4, Scer\HXT9, Scer\MPH3, Scer\AZR1, Scer\HXT8, Scer\HXT14, Scer\VBA5, Scer\YDL199C, Scer\VBA2, Scer\HXT6, Scer\HXT16, Scer\HXT10, Scer\VBA4, Scer\MPH2, Scer\HXT7, Scer\VBA3, Scer\STL1, Scer\ITR2" "Cele\hmit-1.2, Cele\fgt-1" "Xtro\slc2a8, Xtro\slc2a12, Xtro\slc2a6, Xtro\slc2a10" "Mmus\Slc2a10, Mmus\Slc2a13, Mmus\Slc2a6, Mmus\Slc2a12, Mmus\Slc2a8" "Hsap\SLC2A12, Hsap\SLC2A8, Hsap\SLC2A10, Hsap\SLC2A13, Hsap\SLC2A6" viable FBgn0267642 lncRNA:CR45980 - http://flybase.org/reports/FBgn0267642 non_protein_coding_gene - - - CR45980 - CR45980 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0043981 Su(rst)G67 Su(rst)G67 http://flybase.org/reports/FBgn0043981 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "G67, Su(rst)G67" - - 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0039056 CenB1A Centaurin beta 1A http://flybase.org/reports/FBgn0039056 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from electronic annotation with InterPro:IPR001164 GTPase activator activity ; GO:0005096 | inferred from sequence model phospholipid binding ; GO:0005543 | inferred from sequence or structural similarity with HGNC:16922 regulation of GTPase activity ; GO:0043087 | inferred from sequence model cell morphogenesis ; GO:0000902 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from sequence or structural similarity with HGNC:16469 "CenB1A, CG6742, Cen1ba, cenB1A, ACAP" "IPR001164:Arf GTPase activating protein, IPR001849:Pleckstrin homology domain, IPR002110:Ankyrin repeat, IPR011993:PH domain-like, IPR027267:Arfaptin homology (AH) domain/BAR domain, IPR020683:Ankyrin repeat-containing domain" CG6742 27-Aug-18 DroID_v2018_08 "Drer\agap1, Drer\appl1, Drer\acap3a, Drer\asap1b, Drer\acap1, Drer\asap2b, Drer\acap2, Drer\asap2a, Drer\acap3b, Drer\appl2, Drer\zgc:162872, Drer\si:ch211-168b3.1, Drer\unm_sa1614" "Scer\AGE1, Scer\AGE2" "Cele\cnt-2, Cele\cnt-1" "Xtro\asap2, Xtro\acap1, Xtro\acap3, Xtro\appl2, Xtro\asap1, Xtro\appl1, Xtro\acap2" "Mmus\Appl1, Mmus\9030624G23Rik, Mmus\Agap3, Mmus\Asap2, Mmus\Acap1, Mmus\Appl2, Mmus\Asap1, Mmus\Acap2, Mmus\Agap1, Mmus\Asap3, Mmus\Acap3" "Hsap\AGAP1, Hsap\ACAP2, Hsap\ACAP3, Hsap\AGAP3, Hsap\ASAP3, Hsap\APPL1, Hsap\APPL2, Hsap\ACAP1, Hsap\ASAP2, Hsap\ASAP1" "viable,visible" trichogen cell FBgn0266596 asRNA:CR45121 - http://flybase.org/reports/FBgn0266596 non_protein_coding_gene - - - CR45121 - CR45121 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060497 l(3)S107705b lethal (3) S107705b http://flybase.org/reports/FBgn0060497 gene - - - "1077/05, l(3)S107705b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0083091 fermata fermata http://flybase.org/reports/FBgn0083091 gene - meiosis I cytokinesis ; GO:0007110 | inferred from mutant phenotype meiosis II cytokinesis ; GO:0007111 | inferred from mutant phenotype - "fermata, fer" - - 27-Aug-18 DroID_v2018_08 - - - - - - "meiotic cell cycle defective,male,recessive,cytokinesis defective,mitotic cell cycle defective" "spermatid & nucleus | supernumerary,Nebenkern" FBgn0002405 l(3)99Df lethal (3) 99Df http://flybase.org/reports/FBgn0002405 - gene - - - l(3)99Df - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0028263 l(2)56Da lethal (2) 56Da http://flybase.org/reports/FBgn0028263 gene - - - l(2)56Da - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0011445 l(3)neo1 lethal (3) neo1 http://flybase.org/reports/FBgn0011445 - gene - - - l(3)neo1 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0036372 Abp1 Actin binding protein 1 http://flybase.org/reports/FBgn0036372 protein_coding_gene "phosphatidylinositol-3,4,5-trisphosphate binding ; GO:0005547 | inferred from direct assay actin filament binding ; GO:0051015 | inferred from direct assay actin binding ; GO:0003779 | inferred by curator from GO:0005856 actin binding ; GO:0003779 | inferred from sequence or structural similarity phosphatidylinositol-4,5-bisphosphate binding ; GO:0005546 | inferred from direct assay phosphatidylserine binding ; GO:0001786 | inferred from direct assay" chaeta development ; GO:0022416 | inferred from mutant phenotype positive regulation of synaptic growth at neuromuscular junction ; GO:0045887 | inferred from mutant phenotype cell migration ; GO:0016477 | NOT inferred from direct assay terminal button organization ; GO:0072553 | inferred from mutant phenotype actin filament ; GO:0005884 | colocalizes_with inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay neuromuscular junction ; GO:0031594 | inferred from direct assay type Ib terminal bouton ; GO:0061176 | inferred from direct assay type Is terminal bouton ; GO:0061177 | inferred from direct assay growth cone ; GO:0030426 | inferred from direct assay cortical actin cytoskeleton ; GO:0030864 | colocalizes_with inferred from direct assay cytoskeleton ; GO:0005856 | inferred from direct assay axon ; GO:0030424 | inferred from direct assay "CG10083, Abp1, abp1" "IPR001452:SH3 domain, IPR002108:Actin-depolymerising factor homology domain, IPR029006:ADF-H/Gelsolin-like domain" CG10083 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-40c11.2, Drer\dbnlb, Drer\lasp1, Drer\dbnla, Drer\dbn1, Drer\lima1a, Drer\cotl1" Scer\ABP1 "Cele\F42H10.3, Cele\dbn-1" "Xtro\dbnl, Xtro\dbn1" "Mmus\Lasp1, Mmus\Dbnl, Mmus\Dbn1" "Hsap\DBN1, Hsap\LASP1, Hsap\DBNL" "viable,fertile" "microchaeta,dorsocentral bristle" FBgn0028376 gut-X gut-X http://flybase.org/reports/FBgn0028376 gene - - - gut-X - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0083918 CTTbp CTT DNA binding protein http://flybase.org/reports/FBgn0083918 gene - - - CTTbp - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260754 CG42552 - http://flybase.org/reports/FBgn0260754 protein_coding_gene - - - "CG42552, mdcds_30721" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085755 CR40611 - http://flybase.org/reports/FBgn0085755 rRNA_gene - - - CR40611 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0261532 cdm cadmus http://flybase.org/reports/FBgn0261532 protein_coding_gene Ran GTPase binding ; GO:0008536 | inferred from electronic annotation with InterPro:IPR001494 protein transporter activity ; GO:0008565 | inferred from biological aspect of ancestor with PANTHER:PTN000270925 nuclear localization sequence binding ; GO:0008139 | inferred from biological aspect of ancestor with PANTHER:PTN000270925 protein import into nucleus ; GO:0006606 | inferred from biological aspect of ancestor with PANTHER:PTN000270925 neuron-neuron synaptic transmission ; GO:0007270 | inferred from mutant phenotype phototaxis ; GO:0042331 | inferred from mutant phenotype modulation of synaptic transmission ; GO:0050804 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000270925 nuclear membrane ; GO:0031965 | inferred from biological aspect of ancestor with PANTHER:PTN000270925 "3R23, CG7212, cdm, imp13, sd-5, CG 7212, Imp13" "IPR001494:Importin-beta, N-terminal domain, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold, IPR013598:Exportin-1/Importin-beta-like" CG7212 27-Aug-18 DroID_v2018_08 "Drer\si:ch73-182a11.2, Drer\ipo13" "Scer\MTR10, Scer\KAP122" Cele\T16G12.6 Xtro\ipo13 Mmus\Ipo13 Hsap\IPO13 FBgn0022809 E(faf)bE184 Enhancer of faf bE184 http://flybase.org/reports/FBgn0022809 - gene - - - E(faf)bE184 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "eye,wing" FBgn0035949 CG13314 - http://flybase.org/reports/FBgn0035949 protein_coding_gene - - - CG13314 - CG13314 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0041739 l(2)EL3 lethal (2) EL3 http://flybase.org/reports/FBgn0041739 gene - - - l(2)EL3 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0000496 drw droopy wings http://flybase.org/reports/FBgn0000496 - gene - - - "dr, drw" - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive,viable,male,reduced,male sterile,body color defective" "wing,adult cuticle & abdomen,microchaeta,trichome" FBgn0003930 snRNA:U4:39B small nuclear RNA U4 at 39B http://flybase.org/reports/FBgn0003930 "FBgn0003929, FBgn0021997, FBgn0051625" snRNA_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity" U4 snRNP ; GO:0005687 | inferred from sequence or structural similarity "U4:39B, U4, U4-39B, U4-2, K3, l(2)k09410, dU4, snRNA:U4, U4snRNA39B, CR31625, U4snRNA, snRNA:U4:39B, U4 snRNA, U4:39B snRNA, chr2L:21202607..21202764, U4-snRNA" - CR31625 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0065844 l(2)SH0320 lethal (2) SH0320 http://flybase.org/reports/FBgn0065844 gene - - - "l(2)SH0320, l(2)SH2 0320" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0060705 l(3)S070806c lethal (3) S070806c http://flybase.org/reports/FBgn0060705 gene - - - "0708/06, l(3)S070806c" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0039474 CG6283 - http://flybase.org/reports/FBgn0039474 protein_coding_gene phosphatidylcholine 1-acylhydrolase activity ; GO:0008970 | inferred from electronic annotation with InterPro:IPR002334 lipase activity ; GO:0016298 | inferred from sequence or structural similarity with MGI:MGI:96820 lipid catabolic process ; GO:0016042 | inferred from sequence or structural similarity with MGI:MGI:96820 cellular_component ; GO:0005575 | no biological data available "CG6283, DmelL3" "IPR000734:Triacylglycerol lipase family, IPR002334:Vespid venom allergen phospholipase A1, IPR013818:Lipase/vitellogenin, IPR033906:Lipase, N-terminal, IPR029058:Alpha/Beta hydrolase fold" CG6283 27-Aug-18 DroID_v2018_08 "Drer\LOC101884800, Drer\LOC100331214, Drer\lipib, Drer\pla1a, Drer\lpl, Drer\lipg, Drer\lipca, Drer\lipia" - - "Xtro\lipg, Xtro\lpl" "Mmus\Pla1a, Mmus\Pnliprp2, Mmus\Lipg, Mmus\Lipi, Mmus\Pnlip, Mmus\Pnliprp1, Mmus\Lipc, Mmus\Liph, Mmus\Lpl" "Hsap\LIPH, Hsap\LIPG, Hsap\LIPC, Hsap\PNLIP, Hsap\LPL, Hsap\LIPI, Hsap\PLA1A, Hsap\PNLIPRP2, Hsap\PNLIPRP3, Hsap\PNLIPRP1" "visible,partially lethal - majority die,some die during pupal stage" trichogen cell FBgn0004481 l(1)air6 lethal aberrant immune response 6 http://flybase.org/reports/FBgn0004481 - gene - - - "air6, l(1)air[6], l(1)air6" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,melanotic mass phenotype" "embryonic/larval brain,embryonic/larval hindgut,melanotic mass,embryonic/larval proventriculus,foregut imaginal ring,embryonic/larval lymph gland" FBgn0034199 Gbp1 Growth-blocking peptide 1 http://flybase.org/reports/FBgn0034199 protein_coding_gene cytokine activity ; GO:0005125 | inferred from mutant phenotype response to wounding ; GO:0009611 | inferred from mutant phenotype peptidoglycan recognition protein signaling pathway ; GO:0061057 | inferred from genetic interaction with imd inositol phosphate metabolic process ; GO:0043647 | inferred from direct assay positive regulation of homotypic cell-cell adhesion ; GO:0034112 | inferred from direct assay cellular response to amino acid stimulus ; GO:0071230 | inferred from mutant phenotype positive regulation of peptide hormone secretion ; GO:0090277 | inferred from mutant phenotype positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway ; GO:0051482 | inferred from direct assay positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype negative regulation of growth ; GO:0045926 | inferred from mutant phenotype antimicrobial peptide production ; GO:0002775 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred by curator from GO:0005125 "Gbp, CG15917, GBP, Gbp1, gbp1" - CG15917 27-Aug-18 DroID_v2018_08 - - - - - - "developmental rate defective,immune response defective,stress response defective,viable" FBgn0267456 asRNA:CR45806 - http://flybase.org/reports/FBgn0267456 non_protein_coding_gene - - - CR45806 - CR45806 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0052280 CG32280 - http://flybase.org/reports/FBgn0052280 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:GM08588, CG32280" IPR006629:LPS-induced tumour necrosis factor alpha factor CG32280 27-Aug-18 DroID_v2018_08 "Drer\si:dkeyp-75b4.8, Drer\si:ch211-202h22.9, Drer\cdip1, Drer\si:ch211-202h22.7, Drer\si:ch211-157c3.4, Drer\ubald1a, Drer\si:ch211-202h22.8, Drer\litaf" - "Cele\Y37D8A.6, Cele\Y87G2A.19, Cele\F36G3.3, Cele\B0348.1, Cele\C08E8.1, Cele\Y87G2A.18, Cele\Y37D8A.26, Cele\B0348.2, Cele\F16F9.1, Cele\Y37D8A.8, Cele\Y40H7A.11, Cele\Y22D7AL.15" "Xtro\cdip1, Xtro\litaf" "Mmus\Litaf, Mmus\Cdip1" "Hsap\LITAF, Hsap\CDIP1" "viable,fertile" FBgn0260023 veguero veguero http://flybase.org/reports/FBgn0260023 gene - - - veguero - - 27-Aug-18 DroID_v2018_08 - - - - - - chorion | germline clone FBgn0031377 CG15356 - http://flybase.org/reports/FBgn0031377 protein_coding_gene - "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR033482" nucleus ; GO:0005634 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay Sin3-type complex ; GO:0070822 | inferred from direct assay "CG15356, EMSY" "IPR005491:ENT domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR033482:BRCA2-interacting transcriptional repressor EMSY" CG15356 27-Aug-18 DroID_v2018_08 Drer\emsy - - Xtro\emsy Mmus\Emsy Hsap\EMSY FBgn0000694 flrdR flight reduced R http://flybase.org/reports/FBgn0000694 - gene - - - "flrd-R, flrdR" - - 27-Aug-18 DroID_v2018_08 - - - - - - "hypoactive,flight defective" FBgn0052252 asRNA:CR32252 - http://flybase.org/reports/FBgn0052252 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG32252, BcDNA:AT23419, CR32252" - CR32252 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0259857 Su(Ste):CR42426 Su(Ste):CR42426 http://flybase.org/reports/FBgn0259857 non_protein_coding_gene - - - "Su(Ste):CR42426, CR42426" - CR42426 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0003017 ot outheld http://flybase.org/reports/FBgn0003017 - gene - - - "l(1)19Ab, ot" - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive,male sterile,viable,male,reduced,lethal" "wing,ocellar bristle,microchaeta,microchaeta & adult thorax" FBgn0038872 Nelf-A Negative elongation factor A http://flybase.org/reports/FBgn0038872 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with UniProtKB:P92204 negative regulation of transcription from RNA polymerase II promoter during mitosis ; GO:0007070 | inferred from sequence or structural similarity with UniProtKB:P92204 negative regulation of transcription elongation from RNA polymerase II promoter ; GO:0034244 | inferred from direct assay NELF complex ; GO:0032021 | inferred from physical interaction with TH1 transcriptional repressor complex ; GO:0017053 | inferred from sequence or structural similarity with UniProtKB:P92204 nucleus ; GO:0005634 | inferred from direct assay "BcDNA:SD07139, CG5874, Nelf-A, NELF, NELF-A" - CG5874 27-Aug-18 DroID_v2018_08 Drer\nelfa - - Xtro\nelfa Mmus\Nelfa Hsap\NELFA "small body,lethal - all die before end of embryonic stage,germline clone,maternal effect,some die during embryonic stage,lethal" FBgn0032082 CG18088 - http://flybase.org/reports/FBgn0032082 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR017849, InterPro:IPR017850" "metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR017849, InterPro:IPR017850 sensory perception of pain ; GO:0019233 | inferred from mutant phenotype" - "CG18088, gi7297472, gi21430616" "IPR004245:Protein of unknown function DUF229, IPR017850:Alkaline-phosphatase-like, core domain, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha" CG18088 27-Aug-18 DroID_v2018_08 - - "Cele\K03A11.4, Cele\F07C3.3, Cele\M03F8.5, Cele\F32G8.2, Cele\F32D8.2, Cele\T07G12.3, Cele\Y38A10A.2, Cele\T23E1.1, Cele\Y73F8A.35, Cele\R03G8.3, Cele\R03G8.1, Cele\F10C2.3, Cele\F15H10.7, Cele\Y41E3.1" - - - viable FBgn0030868 CG12986 - http://flybase.org/reports/FBgn0030868 protein_coding_gene - - - CG12986 - CG12986 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible,planar polarity defective" trichogen cell FBgn0069339 UY1844 UY1844 http://flybase.org/reports/FBgn0069339 gene - - - UY1844 - - 27-Aug-18 DroID_v2018_08 - - - - - - neuroanatomy defective "mushroom body & axon7B,Kenyon cell" FBgn0262991 asRNA:CR43299 - http://flybase.org/reports/FBgn0262991 non_protein_coding_gene - - - CR43299 - CR43299 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0052672 Atg8a Autophagy-related 8a http://flybase.org/reports/FBgn0052672 protein_coding_gene protein kinase binding ; GO:0019901 | inferred from physical interaction with Atg1 protein tag ; GO:0031386 | inferred from sequence or structural similarity with SGD:S000000174 autophagy ; GO:0006914 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from genetic interaction with daw macroautophagy ; GO:0016236 | inferred from expression pattern regulation of protein ubiquitination ; GO:0031396 | inferred from mutant phenotype regulation of autophagy ; GO:0010506 | inferred from mutant phenotype larval midgut cell programmed cell death ; GO:0035096 | inferred from mutant phenotype autolysosome ; GO:0044754 | inferred from direct assay autophagosome lumen ; GO:0034423 | inferred from direct assay autophagosome ; GO:0005776 | inferred from direct assay amphisome ; GO:0044753 | inferred from direct assay "Atg8a, ATG8a, CG32672, CG1534, BcDNA:LD05816, atg8, atg8a, ATG8, LC3, Atg8/LC3, DrAtg8a, Atg8A, Atg8, atg8A, LC3/Atg8, ATG8/LC3, DmAtg8a, dAtg8a" "IPR004241:Autophagy protein Atg8 ubiquitin-like, IPR029071:Ubiquitin-related domain" CG32672 27-Aug-18 DroID_v2018_08 "Drer\gabarapa, Drer\gabarapl2, Drer\map1lc3b, Drer\zgc:92606, Drer\map1lc3c, Drer\map1lc3a, Drer\map1lc3cl, Drer\gabarapb" Scer\ATG8 "Cele\lgg-3, Cele\lgg-1" "Xtro\map1lc3a, Xtro\gabarapl2, Xtro\gabarapl1, Xtro\map1lc3b, Xtro\map1lc3c" "Mmus\Gabarapl2, Mmus\Map1lc3b, Mmus\Gabarapl1, Mmus\Map1lc3a, Mmus\Gabarap" "Hsap\GABARAP, Hsap\MAP1LC3C, Hsap\MAP1LC3A, Hsap\MAP1LC3B2, Hsap\GABARAPL1, Hsap\GABARAPL2, Hsap\MAP1LC3B" "long lived,memory defective,recessive,short lived,male,melanotic mass phenotype,decreased cell death,viable" "embryonic/larval fat body,somatic clone | third instar larval stage,fat body,embryonic/larval salivary gland" FBgn0267780 lncRNA:CR46111 - http://flybase.org/reports/FBgn0267780 non_protein_coding_gene - - - CR46111 - CR46111 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263949 BG00767 - http://flybase.org/reports/FBgn0263949 gene - - - BG00767 - - 27-Aug-18 DroID_v2018_08 - - - - - - "long lived,starvation stress response defective,temperature response defective,gravitaxis defective,male limited" FBgn0029798 CG4078 - http://flybase.org/reports/FBgn0029798 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR010614 ATP-dependent DNA helicase activity ; GO:0004003 | inferred from sequence or structural similarity with UniProtKB:Q9NZ71 ATP binding ; GO:0005524 | inferred from sequence or structural similarity with UniProtKB:Q9NZ71 telomere maintenance ; GO:0000723 | inferred from electronic annotation with InterPro:IPR030845 DNA replication ; GO:0006260 | inferred from electronic annotation with InterPro:IPR030845 regulation of double-strand break repair via homologous recombination ; GO:0010569 | inferred from sequence or structural similarity with UniProtKB:Q9NZ71 nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q0VGM9 CG4078 "IPR006555:ATP-dependent helicase, C-terminal, IPR013020:DNA helicase (DNA repair), Rad3 type, IPR014013:Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type, IPR030845:Regulator of telomere elongation helicase 1, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR010614:DEAD2, IPR006554:Helicase-like, DEXD box c2 type" CG4078 27-Aug-18 DroID_v2018_08 "Drer\rtel1, Drer\brip1" Scer\CHL1 "Cele\dog-1, Cele\rtel-1" Xtro\brip1 "Mmus\Rtel1, Mmus\Brip1" "Hsap\RTEL1, Hsap\LOC102725121, Hsap\BRIP1" "viable,visible" trichogen cell FBgn0259959 Sfp26Ac Seminal fluid protein 26Ac http://flybase.org/reports/FBgn0259959 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "Sfp26Ac, CG42469" - CG42469 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031722 CG14011 - http://flybase.org/reports/FBgn0031722 protein_coding_gene - lateral inhibition ; GO:0046331 | inferred from mutant phenotype - CG14011 - CG14011 27-Aug-18 DroID_v2018_08 "Drer\LOC103909961, Drer\zgc:153293" - Cele\T12A2.3 - Mmus\Ccdc34 Hsap\CCDC34 "visible,body color defective,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" FBgn0005263 l(3)SG83 lethal (3) SG83 http://flybase.org/reports/FBgn0005263 - gene - - - l(3)SG83 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0052971 CG32971 - http://flybase.org/reports/FBgn0052971 protein_coding_gene RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from electronic annotation with InterPro:IPR009332 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from electronic annotation with InterPro:IPR009332 mediator complex ; GO:0016592 | inferred from biological aspect of ancestor with PANTHER:PTN000277332 CG32971 IPR009332:Mediator of RNA polymerase II transcription subunit 22 CG32971 27-Aug-18 DroID_v2018_08 Drer\med22 - Cele\mdt-22 Xtro\med22 Mmus\Med22 Hsap\MED22 viable FBgn0037853 CG14696 - http://flybase.org/reports/FBgn0037853 protein_coding_gene - - - CG14696 "IPR011021:Arrestin-like, N-terminal, IPR011022:Arrestin C-terminal-like domain, IPR014756:Immunoglobulin E-set" CG14696 27-Aug-18 DroID_v2018_08 "Drer\zgc:110353, Drer\arrdc1b, Drer\arrdc1a, Drer\arrdc3b, Drer\arrdc3a, Drer\txnipa, Drer\LOC799768, Drer\arrdc2, Drer\zgc:110626, Drer\txnipb, Drer\si:ch211-130m23.2" "Scer\CSR2, Scer\RIM8, Scer\ROD1, Scer\ROG3, Scer\LDB19, Scer\ECM21, Scer\ALY1, Scer\ALY2, Scer\ART5" "Cele\arrd-11, Cele\arrd-15, Cele\arrd-3, Cele\arrd-27, Cele\arrd-12, Cele\arrd-22, Cele\arrd-24, Cele\arrd-1, Cele\arrd-5, Cele\arrd-2, Cele\arrd-14, Cele\arrd-13, Cele\rnh-1.2, Cele\arrd-18, Cele\arrd-6, Cele\arrd-25, Cele\arrd-8, Cele\arrd-16, Cele\arrd-7, Cele\arrd-4, Cele\arrd-19, Cele\arrd-23, Cele\arrd-9" "Xtro\txnip, Xtro\arrdc2, Xtro\arrdc3, Xtro\arrdc4" "Mmus\Arrdc4, Mmus\Arrdc2, Mmus\Arrdc5, Mmus\Txnip, Mmus\Arrdc3, Mmus\Arrdc1" "Hsap\ARRDC1, Hsap\ARRDC5, Hsap\ARRDC3, Hsap\TXNIP, Hsap\ARRDC4, Hsap\ARRDC2" viable FBgn0265039 lncRNA:CR44156 - http://flybase.org/reports/FBgn0265039 non_protein_coding_gene - - - CR44156 - CR44156 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0261640 CR42723 - http://flybase.org/reports/FBgn0261640 pseudogene_attribute - - - CR42723 - CR42723 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001839 l(1)ts1082 lethal (1) ts1082 http://flybase.org/reports/FBgn0001839 - gene - - - l(1)ts1082 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,heat sensitive" FBgn0265986 lncRNA:CR44765 - http://flybase.org/reports/FBgn0265986 non_protein_coding_gene - - - CR44765 - CR44765 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037017 CG4074 - http://flybase.org/reports/FBgn0037017 protein_coding_gene protein transporter activity ; GO:0008565 | inferred from biological aspect of ancestor with PANTHER:PTN000260563 protein transporter activity ; GO:0008565 | contributes_to inferred from sequence or structural similarity with SGD:S000003589 "intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000260563 retrograde transport, endosome to Golgi ; GO:0042147 | inferred from sequence or structural similarity with SGD:S000003589" "endosome ; GO:0005768 | inferred from sequence or structural similarity with SGD:S000003589 endosome ; GO:0005768 | inferred from biological aspect of ancestor with PANTHER:PTN000260563 retromer, cargo-selective complex ; GO:0030906 | inferred from sequence or structural similarity with SGD:S000003589" "CG4074, DmDSCR3, DSCR3" IPR028934:Vacuolar protein sorting protein 26 related CG4074 27-Aug-18 DroID_v2018_08 Drer\dscr3 Scer\PEP8 - Xtro\dscr3 Mmus\Dscr3 Hsap\DSCR3 "viable,fertile" FBgn0032404 RpL7-like Ribosomal protein L7-like http://flybase.org/reports/FBgn0032404 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement "neurogenesis ; GO:0022008 | inferred from mutant phenotype maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000463 | inferred from biological aspect of ancestor with PANTHER:PTN000897517 cytoplasmic translation ; GO:0002181 | traceable author statement" cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement "RpL7-like, CG5317" "IPR005998:Ribosomal protein L7, eukaryotic, IPR016082:Ribosomal protein L30, ferredoxin-like fold domain" CG5317 27-Aug-18 DroID_v2018_08 "Drer\rpl7l1, Drer\rpl7" "Scer\RPL7B, Scer\RPL7A, Scer\RLP7" Cele\rpl-7 Xtro\rpl7 "Mmus\Rpl7l1, Mmus\Rpl7, Mmus\Npsr1" "Hsap\NPSR1, Hsap\RPL7L1, Hsap\RPL7" "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell,embryonic/larval salivary gland" FBgn0264311 l(2)k14501 - http://flybase.org/reports/FBgn0264311 gene - - - l(2)k14501 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0005288 mei-1946 meiotic 1946 http://flybase.org/reports/FBgn0005288 - gene - - - "1946, mei-1946" - - 27-Aug-18 DroID_v2018_08 - - - - - - "meiotic cell cycle defective,recessive" meiosis & nuclear chromosome FBgn0005251 l(3)R350 lethal of Roberts 350 http://flybase.org/reports/FBgn0005251 - gene - - - "l(3)350, l(3)R350" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,polyphasic,recessive" FBgn0037205 BoYb Brother of Yb http://flybase.org/reports/FBgn0037205 protein_coding_gene - "negative regulation of transposition, RNA-mediated ; GO:0010526 | inferred from mutant phenotype germ-line stem cell division ; GO:0042078 | inferred from biological aspect of ancestor with PANTHER:PTN001476977" Yb body ; GO:0070725 | inferred from direct assay "CG11133, BoYb" "IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR014014:RNA helicase, DEAD-box type, Q motif" CG11133 27-Aug-18 DroID_v2018_08 "Drer\ddx59, Drer\ddx21, Drer\ddx5, Drer\LOC556764, Drer\tdrd12" "Scer\DBP2, Scer\DBP3" - "Xtro\ddx59, Xtro\gpr149, Xtro\ddx17, Xtro\ddx21, Xtro\ddx5" "Mmus\Ddx17, Mmus\Ddx5, Mmus\Ddx21, Mmus\Tdrd12, Mmus\Ddx50, Mmus\Gpr149, Mmus\Ddx59" "Hsap\DDX50, Hsap\DDX21, Hsap\DDX17, Hsap\TDRD12, Hsap\DDX5, Hsap\GPR149, Hsap\DDX59" "female semi-sterile,female fertile" FBgn0032465 CG12404 - http://flybase.org/reports/FBgn0032465 protein_coding_gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR006977 CG12404 IPR006977:Yip1 domain CG12404 27-Aug-18 DroID_v2018_08 "Drer\yipf5, Drer\zgc:123321" Scer\YIP1 Cele\F32D8.14 Xtro\yipf5 "Mmus\Yipf7, Mmus\Yipf5" "Hsap\YIPF5, Hsap\YIPF7" lethal FBgn0265763 lncRNA:CR44570 - http://flybase.org/reports/FBgn0265763 non_protein_coding_gene - - - CR44570 - CR44570 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260268 GSd450 - http://flybase.org/reports/FBgn0260268 gene - - - GSd450 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,neuroanatomy defective" "ventral nerve cord,longitudinal connective,intersegmental nerve,segmental nerve" FBgn0044001 Su(rst)C379 Su(rst)C379 http://flybase.org/reports/FBgn0044001 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "C379, Su(rst)C379" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040466 Dlip2 Dorsal interacting protein 2 http://flybase.org/reports/FBgn0040466 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR006612 protein binding ; GO:0005515 | inferred from physical interaction with dl protein binding ; GO:0005515 | inferred from physical interaction with Sep1 inferred from physical interaction with Sep2 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "DIP2, dmDIP2, dip2, sip4, CG9771, Dlip2, Dip2" "IPR006612:Zinc finger, C2CH-type" CG9771 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" embryonic/larval hemocyte | third instar larval stage FBgn0060900 l(3)S044205b lethal (3) S044205b http://flybase.org/reports/FBgn0060900 gene - - - "0442/05, l(3)S044205b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0085291 CR34262 - http://flybase.org/reports/FBgn0085291 pseudogene_attribute - - - CR34262 - CR34262 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0024268 acd(2)5D10 auditory courtship defective 5D10 http://flybase.org/reports/FBgn0024268 - gene molecular_function ; GO:0003674 | no biological data available auditory behavior ; GO:0031223 | inferred from mutant phenotype male courtship behavior ; GO:0008049 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "5D10, acd(2)5D10" - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,auditory perception defective,touch sensitivity defective" FBgn0040100 lectin-24Fb lectin-24Fb http://flybase.org/reports/FBgn0040100 gene galactose binding ; GO:0005534 | inferred from sequence or structural similarity - - "AC004373b, AC 004373B, lectin-24Fb" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033789 CG13324 - http://flybase.org/reports/FBgn0033789 protein_coding_gene - - - CG13324 IPR031734:Transcription activator MBF2 CG13324 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0085748 CR40573 - http://flybase.org/reports/FBgn0085748 rRNA_gene - - - CR40573 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000837 fs(1)M21 female sterile (1) M21 http://flybase.org/reports/FBgn0000837 - gene - - - fs(1)M21 - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive,lethal,rescuable maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage" egg FBgn0264672 Eogt EGF-domain O-GlcNAc transferase http://flybase.org/reports/FBgn0264672 protein_coding_gene protein O-GlcNAc transferase activity ; GO:0097363 | inferred from mutant phenotype protein N-acetylglucosaminyltransferase activity ; GO:0016262 | inferred from direct assay protein O-GlcNAc transferase activity ; GO:0097363 | inferred from direct assay metabolic process ; GO:0008152 | inferred from direct assay protein O-linked glycosylation ; GO:0006493 | inferred from mutant phenotype larval chitin-based cuticle development ; GO:0008363 | inferred from mutant phenotype protein O-GlcNAcylation via threonine ; GO:0097370 | inferred from mutant phenotype protein O-linked glycosylation ; GO:0006493 | inferred from direct assay endoplasmic reticulum lumen ; GO:0005788 | inferred from direct assay "Eogt, eogt, CG9867" IPR007657:Glycosyltransferase 61 CG9867 27-Aug-18 DroID_v2018_08 "Drer\eogt, Drer\pomgnt2" - Cele\H12D21.10 "Xtro\eogt, Xtro\pomgnt2" "Mmus\Eogt, Mmus\Pomgnt2" "Hsap\EOGT, Hsap\POMGNT2" FBgn0054056 CG34056 - http://flybase.org/reports/FBgn0054056 protein_coding_gene "glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity ; GO:0016263 | inferred from biological aspect of ancestor with PANTHER:PTN000547277 beta-1,3-galactosyltransferase activity ; GO:0048531 | inferred from direct assay" "protein glycosylation ; GO:0006486 | inferred from direct assay O-glycan processing, core 1 ; GO:0016267 | inferred from biological aspect of ancestor with PANTHER:PTN000547277" membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR003378 cellular_component ; GO:0005575 | no biological data available "CG13904, CG34056, CG13904-1, dC1GalT6" IPR003378:Fringe-like CG34056 27-Aug-18 DroID_v2018_08 "Drer\c1galt1a, Drer\c1galt1c1, Drer\LOC564281, Drer\si:dkey-202e17.1, Drer\c1galt1b" - "Cele\T09E11.6, Cele\E03H4.3, Cele\F56H6.1, Cele\T09E11.12, Cele\Y38C1AB.1, Cele\W09D10.5, Cele\C02H6.1, Cele\C38H2.2, Cele\F37A4.3, Cele\Y38C1AB.5, Cele\bus-4, Cele\C17A2.3, Cele\C16D9.6" "Xtro\c1galt1, Xtro\LOC100496837" "Mmus\C1galt1c1, Mmus\C1galt1" "Hsap\C1GALT1C1, Hsap\C1GALT1" viable DRSC08374 K -1.091978318 -0.12304542 -0.725386361 -0.103073032 1.689179205 -0.025373903 FBgn0010580 l(2)04535b lethal (2) 04535b http://flybase.org/reports/FBgn0010580 - gene - - - "l(2)04535, l(2)04535b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0043998 Su(rst)C478 Su(rst)C478 http://flybase.org/reports/FBgn0043998 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "C478, Su(rst)C478" - - 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0005297 mei-B meiotic B http://flybase.org/reports/FBgn0005297 - gene - - - mei-B - - 27-Aug-18 DroID_v2018_08 - - - - - - "meiotic cell cycle defective,female,recessive,fertile,poor" FBgn0020606 anon-34Da anon-34Da http://flybase.org/reports/FBgn0020606 - gene - - - "cDNA 7, anon-34Da" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259826 ifm(2)RS10 indirect flight muscle (2) RS10 http://flybase.org/reports/FBgn0259826 gene - adult somatic muscle development ; GO:0007527 | inferred from mutant phenotype - ifm(2)RS10 - - 27-Aug-18 DroID_v2018_08 - - - - - - viable indirect flight muscle FBgn0002208 l(3)67BDf lethal (3) 67BDf http://flybase.org/reports/FBgn0002208 - gene - - - l(3)67BDf - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0034598 CG4266 - http://flybase.org/reports/FBgn0034598 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity - - "CG4266, cg4266" "IPR000504:RNA recognition motif domain, IPR006569:CID domain, IPR006903:RNA polymerase II-binding domain, IPR008942:ENTH/VHS" CG4266 27-Aug-18 DroID_v2018_08 "Drer\scaf8, Drer\scaf4b, Drer\scaf4a" Scer\NRD1 Cele\nrd-1 "Xtro\scaf4, Xtro\scaf8" "Mmus\Scaf8, Mmus\Scaf4" "Hsap\SCAF8, Hsap\SCAF4" "visible,body color defective,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" FBgn0260282 GSd478 - http://flybase.org/reports/FBgn0260282 gene - - - GSd478 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0023069 l(1)20Ah lethal (1) 20Ah http://flybase.org/reports/FBgn0023069 - gene - - - "A2/25, l(1)20Ah" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0265803 asRNA:CR44592 - http://flybase.org/reports/FBgn0265803 non_protein_coding_gene - - - "CR44592, Mgn00375" - CR44592 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0044375 anon-AE003825.1 anon-AE003825.1 http://flybase.org/reports/FBgn0044375 gene - - - anon-AE003825.1 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031050 Arp10 Actin-related protein 10 http://flybase.org/reports/FBgn0031050 protein_coding_gene structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity microtubule-based movement ; GO:0007018 | inferred from direct assay cytoskeleton organization ; GO:0007010 | inferred from sequence or structural similarity dynactin complex ; GO:0005869 | inferred from sequence or structural similarity with MGI:MGI:1891654 actin filament ; GO:0005884 | inferred from sequence or structural similarity "CG12235, ARP11, Arp11, Arp10" "IPR004000:Actin family, IPR027127:Actin-related protein 10" CG12235 27-Aug-18 DroID_v2018_08 "Drer\actb1, Drer\si:ch211-241j12.3, Drer\acta2, Drer\actr10, Drer\zgc:86725, Drer\actc1b, Drer\actr1, Drer\ankrd52b, Drer\acta1b, Drer\actc1a, Drer\acta1a, Drer\zgc:86709, Drer\actb2, Drer\si:ch73-187m15.4" "Scer\ACT1, Scer\ARP9, Scer\ARP1, Scer\ARP10" Cele\arp-11 "Xtro\acta2, Xtro\act3, Xtro\actr1a, Xtro\actb, Xtro\actr10, Xtro\actg1, Xtro\actc1, Xtro\ankrd52, Xtro\acta1" "Mmus\Actr10, Mmus\Acta1, Mmus\Actbl2, Mmus\Actl10, Mmus\Acta2, Mmus\Actl9, Mmus\Actrt2, Mmus\Actg2, Mmus\Actl7b, Mmus\Actl7a, Mmus\Actl11, Mmus\Actr1a, Mmus\Actr1b, Mmus\Actrt1, Mmus\Actb, Mmus\Actg1, Mmus\Actc1, Mmus\Actrt3" "Hsap\ACTBL2, Hsap\ACTG1, Hsap\ACTR1A, Hsap\ACTRT1, Hsap\ACTL8, Hsap\POTEJ, Hsap\ACTL7B, Hsap\ACTC1, Hsap\POTEE, Hsap\ACTR10, Hsap\ACTG2, Hsap\ACTL9, Hsap\ACTL7A, Hsap\ACTRT3, Hsap\ACTRT2, Hsap\ACTA1, Hsap\POTEF, Hsap\ACTA2, Hsap\ACTL10, Hsap\ACTB, Hsap\ACTR1B, Hsap\POTEI" "lethal,recessive,partially lethal - majority die,visible" mesothoracic tergum FBgn0042160 CG18837 - http://flybase.org/reports/FBgn0042160 protein_coding_gene - - - CG18837 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0021795 Tapdelta Translocon-associated protein delta http://flybase.org/reports/FBgn0021795 "FBgn0027912, FBgn0064943" protein_coding_gene signal sequence binding ; GO:0005048 | inferred from sequence or structural similarity protein retention in ER lumen ; GO:0006621 | inferred from sequence or structural similarity "endoplasmic reticulum ; GO:0005783 | inferred from electronic annotation with InterPro:IPR008855 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR008855 lipid particle ; GO:0005811 | inferred from direct assay signal recognition particle, endoplasmic reticulum targeting ; GO:0005786 | inferred from sequence or structural similarity endomembrane system ; GO:0012505 | inferred from direct assay" "TRAPdelta, l(2)k17005, Tapdelta, CG9035, BcDNA:GM12291" IPR008855:Translocon-associated CG9035 27-Aug-18 DroID_v2018_08 Drer\ssr4 - Cele\trap-4 Xtro\ssr4 Mmus\Ssr4 Hsap\SSR4 "lethal,recessive,viable" embryonic/larval salivary gland FBgn0264905 lncRNA:CR44096 - http://flybase.org/reports/FBgn0264905 non_protein_coding_gene - - - "CR44096, lincRNA.827" - CR44096 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0070013 BG01228 BG01228 http://flybase.org/reports/FBgn0070013 gene - - - BG01228 - - 27-Aug-18 DroID_v2018_08 - - - - - - stress response defective FBgn0033820 CG4716 - http://flybase.org/reports/FBgn0033820 protein_coding_gene methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity ; GO:0004486 | non-traceable author statement - - "gh18008, BEST:GH18008, CG4716, GH16, Dmel_CG4716" - CG4716 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0028078 l(3)S086405 lethal (3) S086405 http://flybase.org/reports/FBgn0028078 gene - - - "0864/05, l(3)S086405" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0013542 l(2)A1-2-12 lethal (2) A1-2-12 http://flybase.org/reports/FBgn0013542 - gene - - - l(2)A1-2-12 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0053831 His1:CG33831 His1:CG33831 http://flybase.org/reports/FBgn0053831 protein_coding_gene chromatin DNA binding ; GO:0031490 | inferred from sequence or structural similarity with UniProtKB:P07305 "nucleosome assembly ; GO:0006334 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819" "nucleosome ; GO:0000786 | inferred from electronic annotation with InterPro:IPR005818, InterPro:IPR005819 nuclear chromatin ; GO:0000790 | inferred from sequence or structural similarity with UniProtKB:P07305" "CG33831, His1:CG33831" "IPR011991:Winged helix-turn-helix DNA-binding domain, IPR005819:Histone H5, IPR005818:Linker histone H1/H5, domain H15" CG33831 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-108k21.10, Drer\h1f0, Drer\si:ch211-113a14.24, Drer\zgc:110425, Drer\h1fx, Drer\si:ch1073-159d7.7, Drer\zgc:110216, Drer\histh1l, Drer\si:ch73-36p18.1, Drer\zgc:153405, Drer\zgc:163061, Drer\si:dkey-108k21.14, Drer\h1m, Drer\si:dkey-108k21.21, Drer\si:dkey-261m9.12" Scer\HHO1 "Cele\hil-3, Cele\hil-6, Cele\hil-4, Cele\his-24, Cele\hil-1, Cele\hil-5, Cele\hil-2" - "Mmus\H1fnt, Mmus\Hils1, Mmus\Hist1h1e, Mmus\Hist1h1c, Mmus\H1foo, Mmus\Hist1h1d, Mmus\H1fx, Mmus\Hist1h1b, Mmus\Hist1h1t, Mmus\Hist1h1a" "Hsap\HIST1H1T, Hsap\H1FX, Hsap\H1F0, Hsap\HIST1H1A, Hsap\HIST1H1B, Hsap\H1FNT, Hsap\HIST1H1E, Hsap\HIST1H1C, Hsap\HIST1H1D, Hsap\H1FOO" FBgn0060760 l(3)S063319 lethal (3) S063319 http://flybase.org/reports/FBgn0060760 gene - - - "0633/19, l(3)S063319" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0029147 NtR NtR http://flybase.org/reports/FBgn0029147 protein_coding_gene extracellular ligand-gated ion channel activity ; GO:0005230 | inferred from electronic annotation with InterPro:IPR006202 ion transport ; GO:0006811 | inferred from electronic annotation with InterPro:IPR006201 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR006201 "DNtR, CG6698, anon-WO0138359.3, NtR" "IPR006201:Neurotransmitter-gated ion-channel, IPR006202:Neurotransmitter-gated ion-channel ligand-binding domain, IPR022041:Farnesoic acid O-methyl transferase" CG6698 27-Aug-18 DroID_v2018_08 "Drer\chrne, Drer\chrna2a, Drer\si:ch211-39a7.1, Drer\htr3a, Drer\si:ch211-256e16.4, Drer\LOC101882451, Drer\chrna2b, Drer\chrna9, Drer\chrnb3b, Drer\chrnd, Drer\chrna6, Drer\chrna10a, Drer\chrna7, Drer\chrng, Drer\chrnb2l, Drer\chrna3, Drer\chrnb3a, Drer\chrnb1l, Drer\chrna5, Drer\chrna1, Drer\LOC798522, Drer\htr3b, Drer\chrnb4, Drer\chrna4b, Drer\chrnb1, Drer\chrnb2b" - "Cele\acr-19, Cele\acr-15, Cele\eat-2, Cele\acr-16, Cele\acr-14, Cele\W10G11.17, Cele\acr-11, Cele\acr-10, Cele\acr-7, Cele\acr-9, Cele\acr-25" "Xtro\chrnb3, Xtro\chrna1, Xtro\chrnd, Xtro\chrng, Xtro\chrna2, Xtro\chrna9, Xtro\chrna1.2, Xtro\chrna5, Xtro\chrna7, Xtro\chrne, Xtro\chrnb2, Xtro\chrna6" "Mmus\Chrnb1, Mmus\Chrna9, Mmus\Htr3a, Mmus\Chrng, Mmus\Chrna2, Mmus\Chrnd, Mmus\Chrnb3, Mmus\Chrnb4, Mmus\Chrna7, Mmus\Htr3b, Mmus\Chrna5, Mmus\Chrna3, Mmus\Chrna10, Mmus\Chrna6, Mmus\Chrne, Mmus\Chrna1, Mmus\Chrna4, Mmus\Chrnb2" "Hsap\CHRNA6, Hsap\CHRNB2, Hsap\CHRNA7, Hsap\CHRNA5, Hsap\CHRNB3, Hsap\HTR3E, Hsap\HTR3C, Hsap\CHRNA9, Hsap\HTR3B, Hsap\CHRNA4, Hsap\CHRNA2, Hsap\CHRNA3, Hsap\CHRNB1, Hsap\HTR3A, Hsap\CHRNA1, Hsap\HTR3D, Hsap\CHRNA10, Hsap\CHRFAM7A, Hsap\CHRND, Hsap\CHRNG, Hsap\CHRNB4, Hsap\CHRNE" viable FBgn0265455 CG44355 - http://flybase.org/reports/FBgn0265455 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44355 - CG44355 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0083268 E(smoDN)391 Enhancer of smoDN 391 http://flybase.org/reports/FBgn0083268 gene - - - E(smoDN)391 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037845 CG14694 - http://flybase.org/reports/FBgn0037845 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000841430 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000841430 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002666 CG14694 "IPR002666:Reduced folate carrier, IPR020846:Major facilitator superfamily domain" CG14694 27-Aug-18 DroID_v2018_08 "Drer\slc19a1, Drer\slc19a3b, Drer\slc19a2, Drer\slc19a3a" - "Cele\folt-2, Cele\folt-3, Cele\folt-1" "Xtro\slc19a1, Xtro\slc19a2" "Mmus\Slc19a2, Mmus\Slc19a3, Mmus\Slc19a1" "Hsap\SLC19A3, Hsap\C2orf83, Hsap\SLC19A2, Hsap\SLC19A1" viable FBgn0065308 l(2)SH1963 lethal (2) SH1963 http://flybase.org/reports/FBgn0065308 gene - - - "l(2)SH1963, l(2)SH2 1963" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0044072 E(rst)J76 E(rst)J76 http://flybase.org/reports/FBgn0044072 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "J76, E(rst)J76" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0069988 BG02063 BG02063 http://flybase.org/reports/FBgn0069988 gene - - - BG02063 - - 27-Aug-18 DroID_v2018_08 - - - - - - stress response defective FBgn0011365 l(3)j4B9 lethal (3) j4B9 http://flybase.org/reports/FBgn0011365 - gene - - - l(3)j4B9 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0030844 ppk23 pickpocket 23 http://flybase.org/reports/FBgn0030844 protein_coding_gene sodium channel activity ; GO:0005272 | inferred from sequence or structural similarity with MGI:MGI:101782 sodium ion transport ; GO:0006814 | inferred from sequence or structural similarity with MGI:MGI:101782 male courtship behavior ; GO:0008049 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype response to pheromone ; GO:0019236 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with MGI:MGI:101782 "PPK23, CG8527, ppk23, Ppk23" IPR001873:Epithelial sodium channel CG8527 27-Aug-18 DroID_v2018_08 "Drer\asic1a, Drer\asic1b, Drer\asic1c, Drer\asic4b, Drer\asic2, Drer\asic4a" - "Cele\del-7, Cele\acd-1, Cele\acd-3, Cele\flr-1, Cele\delm-1, Cele\acd-2, Cele\acd-5, Cele\acd-4, Cele\delm-2" "Xtro\asic5, Xtro\scnn1b, Xtro\scnn1g, Xtro\asic1, Xtro\asic4, Xtro\scnn1d, Xtro\scnn1a" "Mmus\Asic4, Mmus\Scnn1g, Mmus\Asic2, Mmus\Asic1, Mmus\Asic5, Mmus\Asic3, Mmus\Scnn1a, Mmus\Scnn1b" "Hsap\SCNN1B, Hsap\SCNN1D, Hsap\ASIC1, Hsap\ASIC3, Hsap\SCNN1G, Hsap\ASIC5, Hsap\ASIC4, Hsap\ASIC2, Hsap\SCNN1A" "courtship behavior defective,male,behavior defective,recessive,mating behavior defective,viable,fertile" FBgn0052496 CR32496 - http://flybase.org/reports/FBgn0052496 pseudogene_attribute - - - "CG32496, CR32496, FBpp0074273" - CR32496 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036075 CG8065 - http://flybase.org/reports/FBgn0036075 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG8065 IPR031883:Protein of unknown function DUF4763 CG8065 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0027373 RevIII-7b RevIII-7b http://flybase.org/reports/FBgn0027373 - gene - - - RevIII-7b - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266227 lncRNA:CR44922 - http://flybase.org/reports/FBgn0266227 non_protein_coding_gene - - - "CR44922, lincRNA.670" - CR44922 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263239 dar1 dendritic arbor reduction 1 http://flybase.org/reports/FBgn0263239 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with MGI:MGI:1338056 sequence-specific DNA binding ; GO:0043565 | inferred from direct assay" positive regulation of dendrite morphogenesis ; GO:0050775 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity with MGI:MGI:1338056 positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype positive regulation of dendrite extension ; GO:1903861 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype negative regulation of microtubule depolymerization ; GO:0007026 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "Dar1, CG12029, dar1, l(3)SH5, l(3)63Ed" "IPR013087:Zinc finger C2H2-type, IPR011990:Tetratricopeptide-like helical domain" CG12029 27-Aug-18 DroID_v2018_08 "Drer\klf13, Drer\klf17, Drer\klf1, Drer\klf5a, Drer\klf11a, Drer\klf2a, Drer\klf7a, Drer\klf11b, Drer\klf6a, Drer\sp5l, Drer\klf7b, Drer\sp3b, Drer\sp1, Drer\klf2b, Drer\zgc:153115, Drer\klf5b, Drer\klf8, Drer\klf4, Drer\klf9, Drer\klf5l, Drer\klf12b, Drer\klf12a, Drer\klf6b, Drer\sp3a" "Scer\FZF1, Scer\AZF1, Scer\COM2, Scer\CRZ1, Scer\SWI5, Scer\ACE2" "Cele\sptf-2, Cele\klf-3, Cele\klf-1, Cele\hbl-1, Cele\klf-2" "Xtro\klf4, Xtro\klf7, Xtro\klf2, Xtro\klf3, Xtro\znf534, Xtro\klf11, Xtro\klf13, Xtro\klf9, Xtro\klf8, Xtro\sp1, Xtro\klf12, Xtro\klf5, Xtro\klf10, Xtro\klf17, Xtro\sp5" "Mmus\Klf16, Mmus\Klf9, Mmus\Klf14, Mmus\Klf6, Mmus\Klf8, Mmus\Klf10, Mmus\Klf7, Mmus\Sp5, Mmus\Klf1, Mmus\Klf13, Mmus\Klf4, Mmus\Klf2, Mmus\Klf3, Mmus\Sp3, Mmus\Klf12, Mmus\Klf11, Mmus\Klf5, Mmus\Sp1" "Hsap\KLF1, Hsap\KLF16, Hsap\KLF2, Hsap\SP5, Hsap\KLF10, Hsap\SP1, Hsap\ZNF316, Hsap\KLF14, Hsap\KLF4, Hsap\SP3, Hsap\ZNF853, Hsap\KLF9, Hsap\KLF3, Hsap\KLF7, Hsap\KLF13, Hsap\KLF6, Hsap\KLF5, Hsap\KLF8, Hsap\KLF12" FBgn0039303 CG11857 - http://flybase.org/reports/FBgn0039303 protein_coding_gene - "retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | inferred from biological aspect of ancestor with PANTHER:PTN000078466" integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR004932 CG11857 "IPR004932:Retrieval of early ER protein Rer1, IPR020846:Major facilitator superfamily domain" CG11857 27-Aug-18 DroID_v2018_08 Drer\rer1 Scer\RER1 Cele\rer-1 Xtro\rer1 Mmus\Rer1 Hsap\RER1 viable DRSC14411 E 0.044100295 0.33729703 2.119432512 -0.146064842 0.015953727 0.090314885 FBgn0260742 CG12213 - http://flybase.org/reports/FBgn0260742 protein_coding_gene molecular_function ; GO:0003674 | no biological data available positive regulation of JAK-STAT cascade ; GO:0046427 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG12213, 87A7-9/3, anon-87Ab" - CG12213 27-Aug-18 DroID_v2018_08 Drer\golim4b - - - Mmus\Rnf214 Hsap\RNF214 FBgn0262898 lncRNA:CR43253 - http://flybase.org/reports/FBgn0262898 non_protein_coding_gene - - - "CG43253, CR43253, lincRNA.596" - CR43253 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030347 CG15739 - http://flybase.org/reports/FBgn0030347 protein_coding_gene phosphoprotein phosphatase activity ; GO:0004721 | inferred from sequence or structural similarity with SGD:S000002395 alkaline phosphatase activity ; GO:0004035 | inferred from sequence or structural similarity with SGD:S000002395 phosphatase activity ; GO:0016791 | inferred from direct assay dephosphorylation ; GO:0016311 | inferred from direct assay protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with SGD:S000002395 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000445812 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000002395 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000002395 "CG15739, Phos15739, FPPase, 17945012" "IPR006357:HAD-superfamily hydrolase, subfamily IIA, IPR023214:HAD-like domain" CG15739 27-Aug-18 DroID_v2018_08 "Drer\nipsnap1, Drer\gbas, Drer\pdxp, Drer\lhpp, Drer\pgp" Scer\PHO13 "Cele\K02D10.1, Cele\C53A3.2, Cele\C13C4.4, Cele\F44E7.2, Cele\C45E5.1, Cele\K09H11.7" Xtro\nipsnap1 "Mmus\Gbas, Mmus\Nipsnap1, Mmus\Pgp, Mmus\Lhpp, Mmus\Pdxp" "Hsap\LHPP, Hsap\PDXP, Hsap\PGP, Hsap\NIPSNAP1, Hsap\GBAS" "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0039642 CG11882 - http://flybase.org/reports/FBgn0039642 protein_coding_gene - - - CG11882 IPR028043:Protein of unknown function DUF4506 CG11882 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0259272 C800 - http://flybase.org/reports/FBgn0259272 gene - - - C800 - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,lethal" wing FBgn0278597 lncRNA:CR46267 - http://flybase.org/reports/FBgn0278597 non_protein_coding_gene - - - CR46267 - CR46267 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0027627 qed qed http://flybase.org/reports/FBgn0027627 - gene - - - qed - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "eye,ventral,maxillary palpus" FBgn0267057 asRNA:CR45501 - http://flybase.org/reports/FBgn0267057 non_protein_coding_gene - - - CR45501 - CR45501 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0042695 Nuk Nuk http://flybase.org/reports/FBgn0042695 gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "Dnuk, Nuk" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0027203 l(1)G0423 lethal (1) G0423 http://flybase.org/reports/FBgn0027203 - gene - - - l(1)G0423 - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0028912 tRNA:Pro-AGG-1-2 transfer RNA:Proline-AGG 1-2 http://flybase.org/reports/FBgn0028912 tRNA_gene CCU codon-amino acid adaptor activity ; GO:0033421 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033421 cytosol ; GO:0005829 | inferred by curator from GO:0033421 "BG:DS01486.2, tRNA:pro, AE002690.trna11-ProAGG, tRNA:P:AGG:AE002690-b, CR31983, chr2L.trna20-ProAGG, tRNA-Pro-AGG-1-2, tRNA:Pro-AGG-1-2, tRNA:P:35Ba, CCU" - CR31983 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0058346 CG40346 - http://flybase.org/reports/FBgn0058346 protein_coding_gene - - - CG40346 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0011233 tho thousand points of light http://flybase.org/reports/FBgn0011233 - gene - spermatid development ; GO:0007286 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype - "tho86E, ms(3)04112, tho" - - 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,recessive,partially lethal - majority die" "spermatozoon,spermatid & nucleus,primary spermatocyte cyst,spermatid" FBgn0264358 lncRNA:CR43810 - http://flybase.org/reports/FBgn0264358 non_protein_coding_gene - - - CR43810 - CR43810 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000096 ants antennas http://flybase.org/reports/FBgn0000096 - gene - - - "ants, Ants" - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,good,visible,recessive" antenna FBgn0013755 Bro Brother http://flybase.org/reports/FBgn0013755 - protein_coding_gene protein heterodimerization activity ; GO:0046982 | traceable author statement transcription factor binding ; GO:0008134 | traceable author statement transcription coactivator activity ; GO:0003713 | inferred from direct assay compound eye development ; GO:0048749 | traceable author statement regulation of transcription from RNA polymerase II promoter ; GO:0006357 | traceable author statement regulation of hemocyte proliferation ; GO:0035206 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "bro, rpbeta1, CG7960, Bro" "IPR003417:Core binding factor, beta subunit" CG7960 27-Aug-18 DroID_v2018_08 Drer\cbfb - Cele\bro-1 Xtro\cbfb Mmus\Cbfb Hsap\CBFB embryonic stage

ubiquitous "viable,fertile" embryonic/first instar larval cuticle FBgn0000957 fs(2)E4 female sterile (2) E4 http://flybase.org/reports/FBgn0000957 - gene - - - "fs2.4, fs(2)E4" - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive" "female reproductive system,egg" FBgn0264518 lncRNA:CR43917 - http://flybase.org/reports/FBgn0264518 non_protein_coding_gene - - - "CR43917, lincRNA.429" - CR43917 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0021777 md1 muscle disorganised 1 http://flybase.org/reports/FBgn0021777 - gene - - - md1 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0061435 CG30270 - http://flybase.org/reports/FBgn0061435 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT30770, CG30270" IPR031931:Protein of unknown function DUF4768 CG30270 27-Aug-18 DroID_v2018_08 "Drer\hexb, Drer\hexa" - - Xtro\hexb "Mmus\Hexb, Mmus\Hexa" "Hsap\HEXB, Hsap\HEXA" DRSC22890 I 1.190272924 -1.629845329 0.23415512 -0.059303735 0.134884508 -0.039804856 FBgn0035427 ckd cracked http://flybase.org/reports/FBgn0035427 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "ckd, EP(2)3139, EP(3)0714, EP714, EP3139, BcDNA:RH52423, CG14959, CKD" IPR002557:Chitin binding domain CG14959 27-Aug-18 DroID_v2018_08 - - Cele\Y56A3A.6 - - - "viable,fertile,visible" eye FBgn0027976 l(3)S139308b lethal (3) S139308b http://flybase.org/reports/FBgn0027976 gene - - - "1393/08, l(3)S139308, l(3)S139308b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0083992 Mkp MAP kinase-specific phosphatase http://flybase.org/reports/FBgn0083992 protein_coding_gene protein tyrosine phosphatase activity ; GO:0004725 | inferred from electronic annotation with InterPro:IPR016130 phosphoprotein phosphatase activity ; GO:0004721 | inferred from direct assay MAP kinase tyrosine/serine/threonine phosphatase activity ; GO:0017017 | inferred from sequence or structural similarity with HGNC:3072 protein dephosphorylation ; GO:0006470 | inferred from direct assay cellular_component ; GO:0005575 | no biological data available "CG34099, CG7042, DMKP, Mkp, MKP, mkp" "IPR000340:Dual specificity phosphatase, catalytic domain, IPR000387:Tyrosine specific protein phosphatases domain, IPR016130:Protein-tyrosine phosphatase, active site, IPR020422:Dual specificity protein phosphatase domain, IPR024950:Dual specificity phosphatase, IPR029021:Protein-tyrosine phosphatase-like" CG34099 27-Aug-18 DroID_v2018_08 "Drer\zgc:153044, Drer\dusp10, Drer\ssh1a, Drer\dusp7, Drer\dusp19b, Drer\dusp27, Drer\si:dkey-175m17.7, Drer\dusp8a, Drer\dusp3b, Drer\dusp3a, Drer\si:ch211-121a2.2, Drer\dusp5, Drer\si:ch1073-184j22.2, Drer\styxl1, Drer\dusp22a, Drer\si:ch211-223p8.8, Drer\si:ch211-195b15.8, Drer\dusp19a, Drer\dusp16, Drer\ssh2a, Drer\dusp8b, Drer\dupd1, Drer\dusp22b, Drer\dusp12, Drer\dusp14, Drer\dusp13a, Drer\dusp6, Drer\styx, Drer\si:ch211-203d1.3, Drer\dusp2, Drer\ssh1b, Drer\ssh2b, Drer\dusp4, Drer\zgc:153981, Drer\dusp1" "Scer\YVH1, Scer\PPS1, Scer\SDP1, Scer\MSG5" "Cele\lip-1, Cele\Y54F10BM.13, Cele\F26A3.4, Cele\C24F3.2, Cele\C04F12.8, Cele\F13D11.3, Cele\C16A3.2" "Xtro\dusp4, Xtro\dusp6, Xtro\dusp26, Xtro\styxl1, Xtro\dusp18, Xtro\ssh1, Xtro\dusp19, Xtro\dusp12, Xtro\dusp10, Xtro\dusp1, Xtro\ssh2, Xtro\epm2a, Xtro\dusp5, Xtro\dusp22a, Xtro\styx, Xtro\dusp22, Xtro\dupd1, Xtro\dusp9" "Mmus\Dusp9, Mmus\Dusp12, Mmus\Dusp5, Mmus\Dusp19, Mmus\Dusp2, Mmus\Dusp10, Mmus\Styxl1, Mmus\Dusp22, Mmus\Dusp1, Mmus\Dusp6, Mmus\Dusp21, Mmus\Dusp13, Mmus\Ssh3, Mmus\Dupd1, Mmus\Dusp14, Mmus\Styx, Mmus\Dusp26, Mmus\Dusp7, Mmus\Dusp18, Mmus\Epm2a, Mmus\Ssh1, Mmus\Dusp16, Mmus\Dusp15, Mmus\Dusp8, Mmus\Dusp4, Mmus\Ssh2, Mmus\Dusp27, Mmus\Dusp3" "Hsap\EPM2A, Hsap\STYXL1, Hsap\STYX, Hsap\SSH3, Hsap\SSH1, Hsap\DUSP19, Hsap\SSH2, Hsap\DUSP13, Hsap\DUSP9, Hsap\DUSP6, Hsap\DUSP4, Hsap\DUSP27, Hsap\DUSP22, Hsap\DUSP5, Hsap\DUSP8, Hsap\DUPD1, Hsap\DUSP1, Hsap\DUSP18, Hsap\DUSP21, Hsap\DUSP12, Hsap\DUSP10, Hsap\DUSP16, Hsap\DUSP7, Hsap\DUSP2, Hsap\DUSP15, Hsap\DUSP3, Hsap\DUSP26" "viable,fertile" FBgn0037744 CG8417 - http://flybase.org/reports/FBgn0037744 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001250 mannose-6-phosphate isomerase activity ; GO:0004476 | inferred from biological aspect of ancestor with PANTHER:PTN000034017 carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR001250 GDP-mannose biosynthetic process ; GO:0009298 | inferred from biological aspect of ancestor with PANTHER:PTN000034017 protein glycosylation ; GO:0006486 | inferred from biological aspect of ancestor with PANTHER:PTN000034017 cell wall mannoprotein biosynthetic process ; GO:0000032 | inferred from biological aspect of ancestor with PANTHER:PTN000034017 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000034017 CG8417 "IPR001250:Mannose-6-phosphate isomerase, type I, IPR011051:RmlC-like cupin domain, IPR018050:Phosphomannose isomerase, type I, conserved site, IPR014710:RmlC-like jelly roll fold, IPR016305:Mannose-6-phosphate isomerase" CG8417 27-Aug-18 DroID_v2018_08 Drer\mpi Scer\PMI40 "Cele\C05C8.7, Cele\ZK632.4" Xtro\mpi Mmus\Mpi Hsap\MPI "viable,fertile" DRSC16417 K 0.032044333 -0.721649006 -0.376776952 0.478878772 0.204585862 -1.539098019 FBgn0085472 CG34443 - http://flybase.org/reports/FBgn0085472 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG34443, CG30070" IPR006631:Protein of unknown function DM4/12 CG34443 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0041605 cpx complexin http://flybase.org/reports/FBgn0041605 protein_coding_gene syntaxin binding ; GO:0019905 | inferred from electronic annotation with InterPro:IPR008849 neurotransmitter transporter activity ; GO:0005326 | inferred from sequence or structural similarity with UniProtKB:P63040 neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype synaptic vesicle exocytosis ; GO:0016079 | inferred from mutant phenotype synaptic vesicle exocytosis ; GO:0016079 | inferred from sequence or structural similarity regulation of neurotransmitter secretion ; GO:0046928 | inferred from mutant phenotype synaptic vesicle exocytosis ; GO:0016079 | inferred from sequence or structural similarity with UniProtKB:P63040 modulation of synaptic transmission ; GO:0050804 | inferred from mutant phenotype synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype neuromuscular junction ; GO:0031594 | inferred from direct assay terminal bouton ; GO:0043195 | inferred from direct assay membrane ; GO:0016020 | inferred from sequence or structural similarity with UniProtKB:Q8R1B5 presynaptic active zone ; GO:0048786 | inferred from direct assay membrane ; GO:0016020 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "CG32490, BcDNA:HL04936, BcDNA:RH31085, BcDNA:RH26459, BcDNA:GH27718, cpx, Cpx, dmCplx, DmCpx, CPX" IPR008849:Synaphin CG32490 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-81a5.8, Drer\cplx3a, Drer\cplx2l, Drer\cplx4c, Drer\cplx2, Drer\cplx4b, Drer\LOC563082, Drer\cplx3b, Drer\cplx4a" - "Cele\cpx-2, Cele\cpx-1" "Xtro\cplx2, Xtro\cplx1" "Mmus\Cplx2, Mmus\Cplx3, Mmus\Cplx1, Mmus\Cplx4" "Hsap\CPLX1, Hsap\CPLX3, Hsap\CPLX2, Hsap\CPLX4" "partially lethal,uncoordinated,neurophysiology defective,viable,fertile,heat sensitive,visible,partially lethal - majority die,some die during pupal stage,locomotor behavior defective,sterile,wild-type" "embryonic/larval neuromuscular junction | third instar larval stage,adult neuromuscular junction,embryonic/larval neuromuscular junction,mesothoracic tergum" FBgn0266687 lncRNA:CR45177 - http://flybase.org/reports/FBgn0266687 non_protein_coding_gene - - - CR45177 - CR45177 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038233 HtrA2 HTRA2-related serine protease http://flybase.org/reports/FBgn0038233 protein_coding_gene peptidase activity ; GO:0008233 | inferred from direct assay serine-type endopeptidase activity ; GO:0004252 | inferred from mutant phenotype serine-type endopeptidase activity ; GO:0004252 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q24306 protein binding ; GO:0005515 | inferred from physical interaction with rho-7 regulation of apoptotic process ; GO:0042981 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype ectopic germ cell programmed cell death ; GO:0035234 | inferred from mutant phenotype positive regulation of cysteine-type endopeptidase activity ; GO:2001056 | inferred from direct assay mitochondrion organization ; GO:0007005 | inferred from mutant phenotype positive regulation of apoptotic process ; GO:0043065 | inferred from mutant phenotype mitochondrial intermembrane space ; GO:0005758 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay Nebenkern ; GO:0016006 | inferred from direct assay "CG8464, HtrA2, DmHtrA2, HtrA2/Omi, Omi, dOmi, domi, htrA2, omi, htrA2/omi" "IPR001478:PDZ domain, IPR001940:Peptidase S1C, IPR009003:Peptidase S1, PA clan" CG8464 27-Aug-18 DroID_v2018_08 "Drer\LOC797799, Drer\zgc:174193, Drer\LOC560917, Drer\LOC100003308, Drer\si:dkey-33c12.2, Drer\si:busm1-sl7.7, Drer\LOC799006, Drer\htra3a, Drer\LOC100000024, Drer\si:dkey-84o3.2, Drer\LOC793110, Drer\LOC100331049, Drer\si:dkey-19p15.4, Drer\si:dkey-84o3.7, Drer\si:dkey-112g5.16, Drer\htra1a, Drer\htra4, Drer\LOC793521, Drer\nagk, Drer\zgc:173425, Drer\htra1b, Drer\LOC100149563, Drer\htra3b, Drer\si:dkey-33c12.10, Drer\si:dkey-84o3.3" Scer\NMA111 Cele\C52A11.3 "Xtro\htra1, Xtro\tysnd1, Xtro\htra4, Xtro\nagk" "Mmus\Htra4, Mmus\Htra3, Mmus\Tysnd1, Mmus\Nagk, Mmus\Htra2, Mmus\Htra1" "Hsap\HTRA1, Hsap\NAGK, Hsap\HTRA2, Hsap\HTRA3, Hsap\HTRA4, Hsap\TYSND1" "viable,fertile,radiation resistant,chemical resistant,visible,heat sensitive,male sterile,partially lethal - majority die,male fertile,decreased cell death,female fertile,dominant,flightless,locomotor behavior defective,short lived,chemical sensitive" "eye | pupal stage,eye,heat sensitive,indirect flight muscle,spermatid cyst,investment coneED5644),male germline cell,spermatogonial cyst,mitochondrion & indirect flight muscle,spermatozoon" FBgn0005116 l(1)ff lethal (1) formalin food http://flybase.org/reports/FBgn0005116 - gene - - - "Lff11, l(1)ff" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" "embryonic/larval pharynx,embryonic brain,embryonic segment,embryonic/first instar larval cuticle,dorsal" FBgn0067911 GS(2)A096 GS(2)A096 http://flybase.org/reports/FBgn0067911 gene - - - GS(2)A096 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal "ventral nerve cord commissure,longitudinal connective,RP1 motor neuron,lateral longitudinal fascicle" FBgn0036161 CG7551 - http://flybase.org/reports/FBgn0036161 protein_coding_gene ketohexokinase activity ; GO:0004454 | inferred from sequence or structural similarity with HGNC:6315 fructokinase activity ; GO:0008865 | inferred from sequence or structural similarity with HGNC:6315 fructose metabolic process ; GO:0006000 | inferred from electronic annotation with InterPro:IPR034093 carbohydrate phosphorylation ; GO:0046835 | inferred from sequence or structural similarity with HGNC:6315 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:6315 "BcDNA:AT07524, CG7551" "IPR011611:Carbohydrate kinase PfkB, IPR034093:Ketohexokinase, IPR029056:Ribokinase-like" CG7551 27-Aug-18 DroID_v2018_08 Drer\khk - "Cele\R07H5.8, Cele\grl-29, Cele\grl-5, Cele\grl-18, Cele\grl-26, Cele\grl-31, Cele\grl-27, Cele\grl-30, Cele\grl-3, Cele\grl-28, Cele\grl-21, Cele\grl-15, Cele\grl-20, Cele\grl-6" Xtro\khk Mmus\Khk Hsap\KHK FBgn0040544 CG14700 - http://flybase.org/reports/FBgn0040544 protein_coding_gene - - - CG14700 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0050223 tRNA:His-GTG-1-5 transfer RNA:Histidine-GTG 1-5 http://flybase.org/reports/FBgn0050223 tRNA_gene CAC codon-amino acid adaptor activity ; GO:0033426 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033426 cytosol ; GO:0005829 | inferred by curator from GO:0033426 "AE002787.trna9-HisGTG, tRNA:H:GTG:AE002787-a, tRNA:CR30223, CR30223, tRNA:his:56E, tRNA[His], chr2R.trna67-HisGTG, tRNA-His-GTG-1-5, tRNA:His-GTG-1-5, tRNA:H:56E, CAC" - CR30223 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039058 VhaAC39-2 Vacuolar H[+] ATPase AC39 subunit 2 http://flybase.org/reports/FBgn0039058 protein_coding_gene "proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from sequence or structural similarity with SGD:S000004439" "ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from electronic annotation with InterPro:IPR016727 ATP hydrolysis coupled proton transport ; GO:0015991 | inferred by curator from GO:0033176,GO:0046961 terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" "proton-transporting V-type ATPase, V0 domain ; GO:0033179 | inferred from electronic annotation with InterPro:IPR016727 proton-transporting V-type ATPase complex ; GO:0033176 | inferred from sequence or structural similarity withFB:FBgn0028665" "anon-WO0118547.227, VhaAC39-2, vhaAC39-2, CG4624, V0d" "IPR002843:ATPase, V0 complex, c/d subunit, IPR016727:ATPase, V0 complex, subunit d" CG4624 27-Aug-18 DroID_v2018_08 Drer\atp6v0d1 Scer\VMA6 Cele\vha-16 "Xtro\atp6v0d2, Xtro\atp6v0d1" "Mmus\Atp6v0d2, Mmus\Atp6v0d1" "Hsap\ATP6V0D1, Hsap\ATP6V0D2" viable FBgn0035023 ITP Ion transport peptide http://flybase.org/reports/FBgn0035023 protein_coding_gene "neuropeptide hormone activity ; GO:0005184 | inferred from electronic annotation with InterPro:IPR001166, InterPro:IPR018251 hormone activity ; GO:0005179 | non-traceable author statement neuropeptide hormone activity ; GO:0005184 | non-traceable author statement" circadian sleep/wake cycle ; GO:0042745 | inferred from genetic interaction with Pdf neuropeptide signaling pathway ; GO:0007218 | inferred from expression pattern neuropeptide signaling pathway ; GO:0007218 | non-traceable author statement locomotor rhythm ; GO:0045475 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype circadian rhythm ; GO:0007623 | inferred from expression pattern "extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR001166, InterPro:IPR018251 extracellular space ; GO:0005615 | inferred from sequence model" "CG13586, CHH-like, BcDNA:SD05282, chgh, ITP, DrmITP, DrmITPL1, DrmITPL2, itp, Drm-ITP, Itp" "IPR018251:Crustacean neurohormone, conserved site, IPR001166:Arthropod neurohormone, IPR031098:Arthropod neurohormone/Alpha-latrotoxin associated low molecular weight protein" CG13586 27-Aug-18 DroID_v2018_08 - - "Cele\C05E11.6, Cele\ZC168.2" - - - "viable,visible" "chaeta,supernumerary,trichogen cell" FBgn0267246 asRNA:CR45686 - http://flybase.org/reports/FBgn0267246 non_protein_coding_gene - - - CR45686 - CR45686 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065435 l(2)SH1473 lethal (2) SH1473 http://flybase.org/reports/FBgn0065435 gene - - - "l(2)SH1473, l(2)SH2 1473" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0051814 CG31814 - http://flybase.org/reports/FBgn0051814 protein_coding_gene - - integral component of plasma membrane ; GO:0005887 | inferred from sequence model "BG:DS08249.1, CG31814, 31814" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set" CG31814 27-Aug-18 DroID_v2018_08 "Drer\zgc:172120, Drer\cxcr3.1, Drer\f11r.2, Drer\jam3b, Drer\jam2b, Drer\igsf11, Drer\LOC100151468, Drer\negr1, Drer\si:zfos-1011f11.1, Drer\si:dkey-65b12.12, Drer\lsamp, Drer\vsig8a, Drer\zgc:153911, Drer\ntm, Drer\LOC797620, Drer\jam2a, Drer\zgc:162154, Drer\si:dkey-250k15.10, Drer\zgc:123297, Drer\jam3a, Drer\sc:d0835, Drer\zgc:153073, Drer\si:ch211-9d9.7, Drer\esama, Drer\cxadr, Drer\si:ch211-215e19.3, Drer\zgc:110372, Drer\mxra8b, Drer\vsig8b, Drer\f11r.1, Drer\mxra8a, Drer\opcml, Drer\gpa33, Drer\pigrl4.2, Drer\esamb" - Cele\rig-5 "Xtro\cd276, Xtro\negr1, Xtro\lsamp, Xtro\btn2a2, Xtro\vtcn1, Xtro\ntm" "Mmus\Btnl10, Mmus\Skint1, Mmus\Vtcn1, Mmus\Skint8, Mmus\Igsf5, Mmus\Negr1, Mmus\Cxadr, Mmus\Igsf11, Mmus\Mxra8, Mmus\Esam, Mmus\Iglon5, Mmus\Btnl9, Mmus\Btn2a2, Mmus\Gm1123, Mmus\Skint4, Mmus\Jam3, Mmus\F11r, Mmus\Gpa33, Mmus\Vsig1, Mmus\Skint2, Mmus\Ermap, Mmus\Jam2, Mmus\Pdcd1lg2, Mmus\Vsir, Mmus\Btnl2, Mmus\Clmp, Mmus\Ntm, Mmus\Vsig2, Mmus\Hepacam2, Mmus\Lsamp, Mmus\Opcml, Mmus\Vsig8, Mmus\Skint3, Mmus\Cd276, Mmus\Btn1a1" "Hsap\BTNL2, Hsap\BTN2A2, Hsap\MXRA8, Hsap\BTNL3, Hsap\C10orf54, Hsap\BTNL8, Hsap\F11R, Hsap\VSIG8, Hsap\CXADR, Hsap\CLMP, Hsap\ESAM, Hsap\BTN1A1, Hsap\VSIG2, Hsap\VSIG1, Hsap\LOC102723996, Hsap\VTCN1, Hsap\JAM3, Hsap\OPCML, Hsap\NTM, Hsap\BTN3A1, Hsap\BTN3A3, Hsap\JAM2, Hsap\BTNL9, Hsap\C1orf204, Hsap\LSAMP, Hsap\IGSF11, Hsap\CD276, Hsap\GPA33, Hsap\IGSF5, Hsap\IGLON5, Hsap\BTN3A2, Hsap\CD80, Hsap\ERMAP, Hsap\NEGR1" DRSC01336 IE -2.922077319 -3.235320525 -2.025887636 1.589330465 -0.457304138 1.153801896 FBgn0038460 CG18622 - http://flybase.org/reports/FBgn0038460 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RH18149, CG18622" - CG18622 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0027791 O-fut2 O-fucosyltransferase 2 http://flybase.org/reports/FBgn0027791 - protein_coding_gene peptide-O-fucosyltransferase activity ; GO:0046922 | traceable author statement peptide-O-fucosyltransferase activity ; GO:0046922 | inferred from direct assay "embryo development ; GO:0009790 | non-traceable author statement regulation of transcription, DNA-templated ; GO:0006355 | non-traceable author statement O-glycan processing ; GO:0016266 | traceable author statement O-glycan processing ; GO:0016266 | inferred from direct assay" endoplasmic reticulum ; GO:0005783 | inferred from direct assay Golgi apparatus ; GO:0005794 | inferred from direct assay "O-FUT2, CG14789, EG:BACN32G11.6, O-fut2, O-fut, Ofut2, OFut2" IPR019378:GDP-fucose protein O-fucosyltransferase CG14789 27-Aug-18 DroID_v2018_08 Drer\pofut2 - Cele\pad-2 Xtro\pofut2 Mmus\Pofut2 Hsap\POFUT2 "viable,fertile" FBgn0031068 Alr Augmenter of liver regeneration http://flybase.org/reports/FBgn0031068 protein_coding_gene protein disulfide oxidoreductase activity ; GO:0015035 | inferred from biological aspect of ancestor with PANTHER:PTN000291228 flavin-linked sulfhydryl oxidase activity ; GO:0016971 | inferred from biological aspect of ancestor with PANTHER:PTN000291228 flavin adenine dinucleotide binding ; GO:0050660 | inferred from biological aspect of ancestor with PANTHER:PTN000291228 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR017905 regulation of cell cycle ; GO:0051726 | inferred from direct assay tissue regeneration ; GO:0042246 | inferred from expression pattern inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000291228 "alr, Alr, CG12534" IPR017905:ERV/ALR sulfhydryl oxidase domain CG12534 27-Aug-18 DroID_v2018_08 Drer\gfer "Scer\ERV2, Scer\ERV1" Cele\F56C11.3 Xtro\gfer Mmus\Gfer Hsap\GFER "lethal - all die before end of larval stage,recessive,some die during third instar larval stage" imaginal disc FBgn0266622 asRNA:CR45129 - http://flybase.org/reports/FBgn0266622 non_protein_coding_gene - - - CR45129 - CR45129 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002455 mcd microdiscs http://flybase.org/reports/FBgn0002455 FBgn0004707 gene - - - "l(3)1602, l(3)ds11, l(3)SG8, mcd" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" "imaginal disc,eye-antennal disc,ventral thoracic disc,haltere disc,genital disc" FBgn0005367 Vc Vortice http://flybase.org/reports/FBgn0005367 - gene - - - Vc - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0031545 CG3213 - http://flybase.org/reports/FBgn0031545 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - "bs30c03.y1, CG3213" - CG3213 27-Aug-18 DroID_v2018_08 Drer\odf2a - - Xtro\odf2 Mmus\Odf2 Hsap\ODF2 "viable,visible" "trichogen cell,mesothoracic tergum" DRSC00576 IEK 1.658188609 0.394044859 1.857874755 1.53639671 2.666516006 3.669221064 FBgn0032051 CG13097 - http://flybase.org/reports/FBgn0032051 protein_coding_gene - maturation of SSU-rRNA ; GO:0030490 | inferred from biological aspect of ancestor with PANTHER:PTN000424645 cellular response to starvation ; GO:0009267 | inferred from expression pattern small nucleolar ribonucleoprotein complex ; GO:0005732 | inferred from electronic annotation with InterPro:IPR012173 small-subunit processome ; GO:0032040 | inferred from biological aspect of ancestor with PANTHER:PTN000424645 Mpp10 complex ; GO:0034457 | inferred from biological aspect of ancestor with PANTHER:PTN000424645 CG13097 "IPR012173:U3 small nucleolar ribonucleoprotein complex, subunit Mpp10" CG13097 27-Aug-18 DroID_v2018_08 Drer\mphosph10 Scer\MPP10 Cele\Y75B8A.7 Xtro\mphosph10 Mmus\Mphosph10 Hsap\MPHOSPH10 "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0085306 CG34277 - http://flybase.org/reports/FBgn0085306 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34277 - CG34277 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0058329 CG40329 - http://flybase.org/reports/FBgn0058329 protein_coding_gene - - - CG40329 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0019782 l(1)24 lethal (1) 24 http://flybase.org/reports/FBgn0019782 - gene - - - l(1)24 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0021770 nori-1 nori-1 http://flybase.org/reports/FBgn0021770 - gene - - - nori-1 - - 27-Aug-18 DroID_v2018_08 - - - - - - "paralytic,heat sensitive" FBgn0010901 l(3)06743 lethal (3) 06743 http://flybase.org/reports/FBgn0010901 - gene - - - l(3)06743 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0083314 E(smoDN)1333 Enhancer of smoDN 1333 http://flybase.org/reports/FBgn0083314 gene - - - E(smoDN)1333 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051902 Spn28Da Serpin 28Da http://flybase.org/reports/FBgn0051902 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from biological aspect of ancestor with PANTHER:PTN000156122 negative regulation of proteolysis ; GO:0045861 | inferred from sequence model multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000156122 "CG12318, Spn28Da, CG31902" "IPR000215:Serpin family, IPR023795:Serpin, conserved site, IPR023796:Serpin domain" CG31902 27-Aug-18 DroID_v2018_08 "Drer\si:ch1073-416d2.3, Drer\si:ch211-186e20.7, Drer\serpine1, Drer\serpina7, Drer\serpina10a, Drer\zgc:174259, Drer\serpinb1, Drer\serpine3, Drer\serpinb14, Drer\serpina1l, Drer\serpinh1b, Drer\serpinc1, Drer\serpinb1l4, Drer\serpind1, Drer\serpini1, Drer\serpine2, Drer\serpinb1l2, Drer\serpinb1l1, Drer\serpinh1a, Drer\serpinb1l3, Drer\serpinh2, Drer\zgc:173729" - "Cele\srp-7, Cele\srp-2, Cele\srp-3, Cele\srp-6, Cele\srp-8, Cele\srp-1" "Xtro\serpina10, Xtro\serpina3k, Xtro\serpine1, Xtro\serpinb4, Xtro\serpina3, Xtro\serpina1, Xtro\serpini2, Xtro\serpinb11, Xtro\serpinb6, Xtro\serpinb1, Xtro\serpind1, Xtro\serpine2, Xtro\serpinc1, Xtro\serpini1, Xtro\serpina3m, Xtro\serpinb5" "Mmus\Serpina10, Mmus\Serpinb2, Mmus\Serpinb3b, Mmus\Serpine1, Mmus\Serpini2, Mmus\Serpinb7, Mmus\Serpine2, Mmus\Serpina12, Mmus\Serpina3k, Mmus\Serpinb6d, Mmus\Serpind1, Mmus\Serpini1, Mmus\Serpinb6a, Mmus\Serpinb1c, Mmus\Serpina1e, Mmus\Serpinb9g, Mmus\Serpina16, Mmus\Serpinb9d, Mmus\Serpinb3d, Mmus\Serpinb9c, Mmus\Serpina6, Mmus\Gm11397, Mmus\Serpina5, Mmus\Serpine3, Mmus\Serpina7, Mmus\Serpina3j, Mmus\Serpinb6e, Mmus\Serpina3n, Mmus\Serpinb9f, Mmus\Serpinb3a, Mmus\Serpinb12, Mmus\Serpina1c, Mmus\Serpinc1, Mmus\Serpinb1a, Mmus\Serpinb8, Mmus\Serpina11, Mmus\Serpinb6c, Mmus\Serpinb6b, Mmus\Serpina9, Mmus\Serpinb9, Mmus\Serpina3g, Mmus\Serpinb1b, Mmus\Serpina1d, Mmus\Serpinb11, Mmus\Serpinb9b, Mmus\Serpinh1, Mmus\Serpinb5, Mmus\Serpinb3c, Mmus\Serpina3f, Mmus\Serpinb9e, Mmus\Serpina1a, Mmus\Serpina3a, Mmus\Serpinb13, Mmus\Serpina3c, Mmus\Serpinb10, Mmus\Serping1, Mmus\Serpina3i" "Hsap\SERPINB2, Hsap\SERPINA11, Hsap\SERPINA3, Hsap\SERPINA1, Hsap\SERPINC1, Hsap\SERPINA9, Hsap\SERPINB13, Hsap\SERPINB11, Hsap\SERPINB4, Hsap\SERPINA12, Hsap\SERPINA7, Hsap\SERPINI1, Hsap\SERPINB1, Hsap\SERPINE3, Hsap\SERPINB8, Hsap\SERPINA10, Hsap\SERPINA6, Hsap\SERPINB9, Hsap\SERPINE2, Hsap\HMSD, Hsap\SERPINA5, Hsap\SERPINB5, Hsap\SERPINB10, Hsap\SERPINH1, Hsap\SERPINB7, Hsap\SERPINB6, Hsap\SERPINI2, Hsap\SERPING1, Hsap\SERPINB3, Hsap\SERPINB12, Hsap\SERPINA4, Hsap\SERPIND1, Hsap\SERPINE1" FBgn0264715 lncRNA:CR43983 - http://flybase.org/reports/FBgn0264715 non_protein_coding_gene - - - CR43983 - CR43983 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0261507 CG42655 - http://flybase.org/reports/FBgn0261507 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42655 - CG42655 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0050052 Obp49a Odorant-binding protein 49a http://flybase.org/reports/FBgn0050052 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 extracellular region ; GO:0005576 | inferred from sequence model "Obp49a, CG30052, CG8769, BcDNA:GH25962, DmelObp49a, Obp49A, obp49a" IPR006170:Pheromone/general odorant binding protein CG30052 27-Aug-18 DroID_v2018_08 - - - - - - "chemosensitive behavior defective,viable,visible" "trichogen cell,mesothoracic tergum" FBgn0262607 CG43133 - http://flybase.org/reports/FBgn0262607 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43133 - CG43133 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0069992 BG01891 BG01891 http://flybase.org/reports/FBgn0069992 gene - - - BG01891 - - 27-Aug-18 DroID_v2018_08 - - - - - - stress response defective FBgn0023181 Orc4 Origin recognition complex subunit 4 http://flybase.org/reports/FBgn0023181 - protein_coding_gene DNA replication origin binding ; GO:0003688 | inferred from biological aspect of ancestor with PANTHER:PTN000250139 DNA replication initiation ; GO:0006270 | inferred from direct assay nuclear origin of replication recognition complex ; GO:0005664 | inferred from direct assay "rDmORC, ORC4, orc4, ORC, DmORC4, CG2917, Orc4, dmOrc4" "IPR003593:AAA+ ATPase domain, IPR016527:Origin recognition complex subunit 4, IPR032705:Origin recognition complex subunit 4, C-terminal, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG2917 27-Aug-18 DroID_v2018_08 Drer\orc4 Scer\ORC4 - Xtro\orc4 Mmus\Orc4 Hsap\ORC4 embryonic stage && larval stage "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0015928 dfc defaced http://flybase.org/reports/FBgn0015928 - gene - - - dfc - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,heat sensitive" "mouth hooks,lateral process,dorsal bridge" FBgn0267577 lncRNA:CR45917 - http://flybase.org/reports/FBgn0267577 non_protein_coding_gene - - - "CR45917, pri-mir-92b" - CR45917 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032422 atilla atilla http://flybase.org/reports/FBgn0032422 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG6579, atilla" - CG6579 27-Aug-18 DroID_v2018_08 - - "Cele\C15H9.9, Cele\K11H12.7, Cele\K11H12.6" - - - "viable,fertile" FBgn0000627 Eyl Eyeluf http://flybase.org/reports/FBgn0000627 - gene - - - Eyl - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "eye,antenna" FBgn0035155 RabX6 RabX6 http://flybase.org/reports/FBgn0035155 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR005225 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11" lipid particle organization ; GO:0034389 | inferred from biological aspect of ancestor with PANTHER:PTN000756441 vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 neuronal cell body ; GO:0043025 | inferred from direct assay "RabX6, CG12015, DmRabX6, rabx6, rabX6" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG12015 27-Aug-18 DroID_v2018_08 "Drer\rab2a, Drer\rab18a, Drer\LOC100330257, Drer\dnajc27, Drer\rab18b" Scer\YPT7 Cele\rab-18 "Xtro\rab2a, Xtro\rab39a, Xtro\rab2b, Xtro\dnajc27" "Mmus\Rab2b, Mmus\Rab18, Mmus\Dnajc27, Mmus\Rab2a, Mmus\Agap1, Mmus\Rab42" "Hsap\RAB18, Hsap\AGAP1, Hsap\AGAP4, Hsap\RAB2B, Hsap\RAB2A, Hsap\DNAJC27" "partially lethal - majority die,some die during pupal stage" FBgn0030944 CG6617 - http://flybase.org/reports/FBgn0030944 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon-EST:Posey180, CG6617" "IPR024964:CTLH/CRA C-terminal to LisH motif domain, IPR006594:LIS1 homology motif, IPR006595:CTLH, C-terminal LisH motif, IPR013144:CRA domain" CG6617 27-Aug-18 DroID_v2018_08 "Drer\gid8b, Drer\gid8a" Scer\GID8 Cele\tag-304 Xtro\gid8 Mmus\Gid8 Hsap\GID8 FBgn0060433 l(3)S125414b lethal (3) S125414b http://flybase.org/reports/FBgn0060433 gene - - - "1254/14, l(3)S125414b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0265993 lncRNA:CR44768 - http://flybase.org/reports/FBgn0265993 non_protein_coding_gene - - - "CR44768, lincRNA.186" - CR44768 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001747 l(1)HM19 lethal (1) HM19 http://flybase.org/reports/FBgn0001747 - gene - - - l(1)HM19 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,cold sensitive" FBgn0025809 Paf-AHalpha Platelet-activating factor acetylhydrolase alpha http://flybase.org/reports/FBgn0025809 - protein_coding_gene 1-alkyl-2-acetylglycerophosphocholine esterase activity ; GO:0003847 | NOT inferred from direct assay - - "AAC83820, PAFAHalpha, CG8962, Paf-AHalpha, Dmaalpha[[PAFAH]]" IPR013830:SGNH hydrolase-type esterase domain CG8962 27-Aug-18 DroID_v2018_08 "Drer\ice1, Drer\pafah1b3, Drer\pafah1b2" - - "Xtro\pafah1b2, Xtro\pafah1b3" "Mmus\Ice1, Mmus\Pafah1b3, Mmus\Pafah1b2" "Hsap\PAFAH1B2, Hsap\PAFAH1B3, Hsap\ICE1" viable FBgn0003877 tu(2)48j tumor(2)48j http://flybase.org/reports/FBgn0003877 - gene - - - "tu-48j, tu(2)48j" - - 27-Aug-18 DroID_v2018_08 - - - - - - melanotic mass phenotype FBgn0028407 Drep3 DNA fragmentation factor-related protein 3 http://flybase.org/reports/FBgn0028407 protein_coding_gene - regulation of apoptotic process ; GO:0042981 | inferred from biological aspect of ancestor with PANTHER:PTN000959605 neurogenesis ; GO:0022008 | inferred from mutant phenotype intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR003508 "drep3, BcDNA:AT08574, CG13187, CG8364, Drep-3, Drep3, DREP-3, Rep3, drep-3" IPR003508:CIDE-N domain CG8364 27-Aug-18 DroID_v2018_08 "Drer\cidec, Drer\dffa, Drer\cidea, Drer\cideb" - - "Xtro\cidea, Xtro\cidec, Xtro\cideb" "Mmus\Cideb, Mmus\Cidec, Mmus\Cidea, Mmus\Dffa" "Hsap\CIDEB, Hsap\CIDEA, Hsap\CIDEC, Hsap\DFFA" "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0261629 CG42712 - http://flybase.org/reports/FBgn0261629 protein_coding_gene - - - CG42712 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0029893 CG14442 - http://flybase.org/reports/FBgn0029893 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR023753 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR023753 sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - CG14442 "IPR015943:WD40/YVTN repeat-like-containing domain, IPR023753:FAD/NAD(P)-binding domain" CG14442 27-Aug-18 DroID_v2018_08 - - Cele\C05D11.13 Xtro\znf821 Mmus\Zfp821 Hsap\ZNF821 "viable,fertile,visible" mesothoracic tergum FBgn0013434 btd::Mmmm\Sp1 btd::Mmmm\Sp1 http://flybase.org/reports/FBgn0013434 - engineered_fusion_gene - - - "btd::mammal\Sp1, btd::Mmmm\Sp1" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265799 lncRNA:CR44588 - http://flybase.org/reports/FBgn0265799 non_protein_coding_gene - - - CR44588 - CR44588 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0069417 JJF137 JJF137 http://flybase.org/reports/FBgn0069417 gene - - - JJF137 - - 27-Aug-18 DroID_v2018_08 - - - - - - stress response defective FBgn0264392 lncRNA:CR43840 - http://flybase.org/reports/FBgn0264392 non_protein_coding_gene - - - CR43840 - CR43840 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0045865 blood\ORF1 blood element ORF1 http://flybase.org/reports/FBgn0045865 transposable_element_gene - - - blood\ORF1 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0013244 E(var)261 E(var)261 http://flybase.org/reports/FBgn0013244 - gene - - - E(var)261 - - 27-Aug-18 DroID_v2018_08 - - - - - - "enhancer of variegation,dominant" FBgn0010188 tu-36e tu-36e http://flybase.org/reports/FBgn0010188 - gene - - - tu-36e - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030896 CG12612 - http://flybase.org/reports/FBgn0030896 protein_coding_gene - - - CG12612 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085333 CG34304 - http://flybase.org/reports/FBgn0085333 protein_coding_gene - - - CG34304 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262611 CG43137 - http://flybase.org/reports/FBgn0262611 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43137, lincRNA.952" - CG43137 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0069056 CG33226 - http://flybase.org/reports/FBgn0069056 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" cellular_component ; GO:0005575 | no biological data available "SP37, SPH37, CG10450, CG33226" "IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR001314:Peptidase S1A, chymotrypsin family, IPR033116:Serine proteases, trypsin family, serine active site" CG33226 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-165b19.9, Drer\cfd, Drer\ovch1, Drer\si:ch211-165b19.8, Drer\zgc:165423, Drer\si:dkey-16l2.17, Drer\gzm3, Drer\LOC100004427, Drer\zgc:163079, Drer\gzmk, Drer\si:ch211-165b19.5, Drer\zgc:92313, Drer\si:dkey-21e2.15, Drer\LOC558805, Drer\si:dkeyp-93a5.3, Drer\si:dkey-21e2.7, Drer\gzma, Drer\si:dkey-21e2.12" - "Cele\try-1, Cele\try-3, Cele\try-6" - "Mmus\Mcpt4, Mmus\Ctsg, Mmus\Gzmb, Mmus\Mcpt9, Mmus\Mcpt8, Mmus\Mcpt1, Mmus\Klk9, Mmus\Klk6, Mmus\Gzmc, Mmus\Gzmg, Mmus\Gzmf, Mmus\Cma1, Mmus\Gzme, Mmus\Gzmd, Mmus\Cma2, Mmus\Klk15" "Hsap\MASP1, Hsap\CMA1, Hsap\GZMB, Hsap\KLK15, Hsap\CTSG, Hsap\GZMH, Hsap\KLK9" FBgn0062691 EP1350 EP1350 http://flybase.org/reports/FBgn0062691 gene - - - "EP(X)1350, EP1350" - - 27-Aug-18 DroID_v2018_08 - - - - - - visible eye FBgn0260452 CG13984 - http://flybase.org/reports/FBgn0260452 protein_coding_gene - - - CG13984 - CG13984 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0062689 EP1388 EP1388 http://flybase.org/reports/FBgn0062689 gene - - - "EP(X)1388, EP1388" - - 27-Aug-18 DroID_v2018_08 - - - - - - spermatogonium FBgn0262543 lncRNA:CR43097 - http://flybase.org/reports/FBgn0262543 non_protein_coding_gene - - - "CG43097, CR43097" - CR43097 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0014865 Mtk Metchnikowin http://flybase.org/reports/FBgn0014865 FBgn0061385 protein_coding_gene - defense response to fungus ; GO:0050832 | traceable author statement response to bacterium ; GO:0009617 | inferred from direct assay defense response to Gram-positive bacterium ; GO:0050830 | inferred from direct assay defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype antibacterial humoral response ; GO:0019731 | inferred from expression pattern defense response ; GO:0006952 | inferred from direct assay antifungal humoral response ; GO:0019732 | traceable author statement antifungal humoral response ; GO:0019732 | inferred from expression pattern response to bacterium ; GO:0009617 | inferred from expression pattern defense response to fungus ; GO:0050832 | inferred from direct assay defense response to Gram-positive bacterium ; GO:0050830 | traceable author statement extracellular region ; GO:0005576 | inferred from direct assay "Mtk, Metch, METCH, metch, Metc, CG8175, mtk, metk, DIM 17, BcDNA:RH07954" IPR012513:Metchnikowin CG8175 27-Aug-18 DroID_v2018_08 - - - - - - embryonic stage | 6-24 hr viable FBgn0038706 CG3517 - http://flybase.org/reports/FBgn0038706 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG3517 - CG3517 27-Aug-18 DroID_v2018_08 - - - - - - "visible,body color defective,lethal - all die before end of pupal stage,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0005197 l(3)36d24 lethal (3) 36d24 http://flybase.org/reports/FBgn0005197 - gene - - - l(3)36d24 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0028887 CG3491 - http://flybase.org/reports/FBgn0028887 protein_coding_gene - "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR026741" - "BG:DS03323.1, CG3491" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR026937:Strawberry notch, helicase C domain, IPR026741:Protein strawberry notch" CG3491 27-Aug-18 DroID_v2018_08 "Drer\si:ch73-63e15.2, Drer\sbno1, Drer\sbno2a" - Cele\let-765 Xtro\sbno2 "Mmus\Sbno1, Mmus\Sbno2" "Hsap\SBNO1, Hsap\SBNO2" viable FBgn0262000 CG42818 - http://flybase.org/reports/FBgn0262000 protein_coding_gene - - - "CG42818, DS07473.1A, BG:DS07473.1, CG12455" - CG42818 27-Aug-18 DroID_v2018_08 "Drer\cacna2d1a, Drer\cacna2d4a, Drer\cacna2d3, Drer\cacna2d2b, Drer\cacna2d4b, Drer\cachd1" - - "Xtro\cacna2d2, Xtro\cacna2d4, Xtro\cachd1, Xtro\cacna2d1" "Mmus\Cacna2d2, Mmus\Cacna2d3, Mmus\Cacna2d1, Mmus\Cacna2d4, Mmus\Cachd1" "Hsap\CACHD1, Hsap\CACNA2D3, Hsap\CACNA2D2, Hsap\CACNA2D4, Hsap\CACNA2D1" FBgn0263556 mir-4940 mir-4940 stem loop http://flybase.org/reports/FBgn0263556 miRNA_gene - - - "mir-4940, dme-mir-4940, CR43541" - CR43541 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0028647 CG11902 - http://flybase.org/reports/FBgn0028647 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 "anon-96CDa, CG11902" "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG11902 27-Aug-18 DroID_v2018_08 "Drer\znf574, Drer\znf1035, Drer\znf1007, Drer\si:ch211-216l23.1, Drer\znf1004, Drer\znf366, Drer\si:dkey-253d23.2, Drer\znf710b, Drer\znf1010, Drer\si:ch211-261d7.6, Drer\si:ch211-266d19.4, Drer\znf407, Drer\zgc:66448, Drer\si:dkey-30k6.5, Drer\znf710a, Drer\znf142, Drer\znf983" - Cele\Y48G8AL.10 "Xtro\znf142, Xtro\znf423, Xtro\znf91" "Mmus\Zfp423, Mmus\Zfp62, Mmus\Zfp710, Mmus\Gm14124, Mmus\Zfp366, Mmus\Zfp521, Mmus\Zfp236, Mmus\Zfp142, Mmus\Zfp865, Mmus\Zfp729a, Mmus\Zfp619, Mmus\Zfp646" "Hsap\ZNF521, Hsap\ZNF423, Hsap\ZNF808, Hsap\ZFP62, Hsap\ZNF197, Hsap\ZNF710, Hsap\ZNF226, Hsap\ZNF850, Hsap\ZNF836, Hsap\ZNF845, Hsap\ZNF366, Hsap\ZNF407, Hsap\ZNF236, Hsap\ZNF780B, Hsap\ZNF99, Hsap\ZNF462, Hsap\ZNF624, Hsap\ZNF91, Hsap\ZNF585A, Hsap\ZNF729, Hsap\ZNF208, Hsap\ZNF646, Hsap\ZNF721" viable FBgn0001157 gustE gustatory-defective E http://flybase.org/reports/FBgn0001157 - gene - - - gustE - - 27-Aug-18 DroID_v2018_08 - - - - - - "taste perception defective,recessive" taste bristle FBgn0060666 l(3)S080503 lethal (3) S080503 http://flybase.org/reports/FBgn0060666 gene - - - "0805/03, l(3)S080503" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0265365 lncRNA:CR44306 - http://flybase.org/reports/FBgn0265365 non_protein_coding_gene - - - CR44306 - CR44306 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065644 l(2)SH0753 lethal (2) SH0753 http://flybase.org/reports/FBgn0065644 gene - - - "l(2)SH0753, l(2)SH2 0753" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0010112 fs(1)de4 female sterile (1) defective eggs 4 http://flybase.org/reports/FBgn0010112 - gene - - - "de4, fs(1)de4" - - 27-Aug-18 DroID_v2018_08 - - - - - - female sterile "endochorion,dorsal appendage,chorion" FBgn0035333 CG1317 - http://flybase.org/reports/FBgn0035333 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR011016 ubiquitin protein ligase activity involved in ERAD pathway ; GO:1904264 | inferred from biological aspect of ancestor with PANTHER:PTN000322018 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:30550 zinc ion binding ; GO:0008270 | inferred from sequence model protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with HGNC:30550 ER-associated ubiquitin-dependent protein catabolic process ; GO:0030433 | inferred from biological aspect of ancestor with PANTHER:PTN000322018 integral component of endoplasmic reticulum membrane ; GO:0030176 | inferred from biological aspect of ancestor with PANTHER:PTN000322018 integral component of endoplasmic reticulum membrane ; GO:0030176 | inferred from sequence or structural similarity with HGNC:30550 CG1317 "IPR011016:Zinc finger, RING-CH-type, IPR011990:Tetratricopeptide-like helical domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG1317 27-Aug-18 DroID_v2018_08 "Drer\march2, Drer\zgc:158785, Drer\march6, Drer\march4, Drer\zgc:153256, Drer\march11, Drer\march9, Drer\march7, Drer\march8" Scer\SSM4 "Cele\marc-5, Cele\marc-1, Cele\marc-6" "Xtro\march2, Xtro\march7, Xtro\march3, Xtro\march6, Xtro\march1, Xtro\march8, Xtro\march4, Xtro\march11, Xtro\march9" "Mmus\March1, Mmus\March9, Mmus\March11, Mmus\March3, Mmus\March10, Mmus\March6, Mmus\March8, Mmus\March2, Mmus\March4" "Hsap\MARCH1, Hsap\MARCH2, Hsap\MARCH9, Hsap\MARCH6, Hsap\MARCH4, Hsap\MARCH10, Hsap\MARCH8, Hsap\MARCH7, Hsap\MARCH11, Hsap\MARCH3" "viable,fertile" FBgn0265634 lncRNA:CR44441 - http://flybase.org/reports/FBgn0265634 non_protein_coding_gene - - - "CR44441, lincRNA.S8353" - CR44441 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002415 l(3)DTS2 lethal (3) DTS2 http://flybase.org/reports/FBgn0002415 - gene - - - "DTS-2, l(3)DTS2" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,dominant,heat sensitive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0039938 Sox102F Sox102F http://flybase.org/reports/FBgn0039938 protein_coding_gene - positive regulation of heart contraction ; GO:0045823 | inferred from mutant phenotype - "CG11153, Sox D, SOXD, SOX102D, SoxD, Sox102D, Sox102F" IPR009071:High mobility group box domain CG11153 27-Aug-18 DroID_v2018_08 "Drer\sox6, Drer\sox5" Scer\ROX1 Cele\egl-13 "Xtro\sox13, Xtro\sox6, Xtro\sox5" "Mmus\Sox6, Mmus\Sox13, Mmus\Sox5" "Hsap\SOX6, Hsap\SOX5, Hsap\SOX13" "visible,viable" "adult heart,myofibrilhow-24B,wing,wing vein L2,wing vein L3,ectopic,eye" FBgn0013245 E(var)27 E(var)27 http://flybase.org/reports/FBgn0013245 - gene - - - E(var)27 - - 27-Aug-18 DroID_v2018_08 - - - - - - "enhancer of variegation,dominant" FBgn0000185 bie bientot http://flybase.org/reports/FBgn0000185 - gene - - - bie - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive,visible,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage,maternal effect" "stage 5 embryo,embryonic/first instar larval cuticle,tergite" FBgn0032899 CG9338 - http://flybase.org/reports/FBgn0032899 protein_coding_gene - - - "BcDNA:GH07967, CG9338" - CG9338 27-Aug-18 DroID_v2018_08 - - "Cele\C15H9.9, Cele\K11H12.7, Cele\F35C5.11, Cele\K11H12.6" - - - viable DRSC24503 K -0.326292227 0.258428317 -0.185042133 -0.249631514 -0.100595605 -1.67004944 FBgn0002148 l(2)K534 lethal (2) K534 http://flybase.org/reports/FBgn0002148 - gene - - - l(2)K534 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0025128 su(RpII140[Z36])S19 su(RpII140[Z36])S19 http://flybase.org/reports/FBgn0025128 - gene - - - "Z36[S19], su(RpII140[Z36])S19" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267174 lncRNA:CR45614 - http://flybase.org/reports/FBgn0267174 non_protein_coding_gene - - - CR45614 - CR45614 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0024576 l(3)rK344 lethal (3) rK344 http://flybase.org/reports/FBgn0024576 - gene - - - l(3)rK344 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0061049 l(3)S023434b lethal (3) S023434b http://flybase.org/reports/FBgn0061049 gene - - - "0234/34, l(3)S023434b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0022239 l(2)k02505 lethal (2) k02505 http://flybase.org/reports/FBgn0022239 - gene - - - l(2)k02505 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0035830 CG8209 - http://flybase.org/reports/FBgn0035830 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "anon-WO0172774.138, CG8209" "IPR015940:Ubiquitin-associated domain, IPR001012:UBX domain, IPR009060:UBA-like, IPR013087:Zinc finger C2H2-type, IPR029071:Ubiquitin-related domain" CG8209 27-Aug-18 DroID_v2018_08 "Drer\si:ch73-173p19.1, Drer\ubxn1" "Scer\UBX7, Scer\UBX6" "Cele\ubxn-4, Cele\ubxn-1" "Xtro\ubxn1, Xtro\ubxn4" "Mmus\Ubxn1, Mmus\Ubxn4" "Hsap\UBXN4, Hsap\UBXN1" "viable,fertile" FBgn0062580 Mod(var)26 Mod(var)26 http://flybase.org/reports/FBgn0062580 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "26, Mod(var)26" - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation" FBgn0051342 CG31342 - http://flybase.org/reports/FBgn0051342 protein_coding_gene - - - "CG7472, CG18551, CG31342" IPR011993:PH domain-like CG31342 27-Aug-18 DroID_v2018_08 "Drer\sdcbp, Drer\sdcbp2" - - Xtro\sdcbp "Mmus\Sdcbp2, Mmus\Sdcbp" "Hsap\SDCBP, Hsap\SDCBP2" FBgn0028185 l(3)S024020a lethal (3) S024020a http://flybase.org/reports/FBgn0028185 gene - - - "0240/20, l(3)S024020, l(3)S024020a" - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,lethal,recessive" FBgn0002830 ms(2)E9 male sterile (2) E9 http://flybase.org/reports/FBgn0002830 - gene - - - "ms2.9, ms(2)2.9, ms(2)E9" - - 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,recessive" FBgn0060478 l(3)S111116b lethal (3) S111116b http://flybase.org/reports/FBgn0060478 gene - - - "1111/16, l(3)S111116b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0038643 CG14300 - http://flybase.org/reports/FBgn0038643 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 molecular_function ; GO:0003674 | no biological data available chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 biological_process ; GO:0008150 | no biological data available extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 cellular_component ; GO:0005575 | no biological data available CG14300 IPR002557:Chitin binding domain CG14300 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible" trichogen cell FBgn0036942 CG7328 - http://flybase.org/reports/FBgn0036942 protein_coding_gene fructokinase activity ; GO:0008865 | inferred from sequence or structural similarity with HGNC:6315 ketohexokinase activity ; GO:0004454 | inferred from sequence or structural similarity with HGNC:6315 fructose metabolic process ; GO:0006000 | inferred from electronic annotation with InterPro:IPR034093 carbohydrate phosphorylation ; GO:0046835 | inferred from sequence or structural similarity with HGNC:6315 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:6315 CG7328 "IPR002173:Carbohydrate/puine kinase, PfkB, conserved site, IPR011611:Carbohydrate kinase PfkB, IPR034093:Ketohexokinase, IPR029056:Ribokinase-like" CG7328 27-Aug-18 DroID_v2018_08 Drer\khk Scer\RBK1 "Cele\grl-3, Cele\grl-29, Cele\grl-31, Cele\grl-5, Cele\grl-27, Cele\grl-21, Cele\grl-28, Cele\grl-15, Cele\grl-30, Cele\R07H5.8, Cele\grl-20, Cele\grl-26, Cele\grl-18, Cele\grl-6" Xtro\khk Mmus\Khk Hsap\KHK viable DRSC10812 K 0.606226763 0.042808107 -1.140026465 0.332921219 -0.024964772 2.220670415 FBgn0015496 l(3)65ACf lethal (3) 65ACf http://flybase.org/reports/FBgn0015496 - gene - - - "VI, l(3)65ACf, l(3)k65ACf" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0000010 aa anarista http://flybase.org/reports/FBgn0000010 - gene - - - "al-b, aa" - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive" "arista,wing" FBgn0050413 CG30413 - http://flybase.org/reports/FBgn0050413 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG30413 IPR031734:Transcription activator MBF2 CG30413 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0033090 CG15909 - http://flybase.org/reports/FBgn0033090 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15909 - CG15909 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0016990 ms(3)1342A ms(3)1342A http://flybase.org/reports/FBgn0016990 - gene - - - ms(3)1342A - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0019788 l(1)15 lethal (1) 15 http://flybase.org/reports/FBgn0019788 - gene - - - l(1)15 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0033225 TTLL12 - http://flybase.org/reports/FBgn0033225 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR013815 catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR013815 cellular protein modification process ; GO:0006464 | inferred from electronic annotation with InterPro:IPR004344 - CG1550 "IPR004344:Tubulin-tyrosine ligase/Tubulin polyglutamylase, IPR013815:ATP-grasp fold, subdomain 1, IPR027749:Tubulin--tyrosine ligase-like protein 12" CG1550 27-Aug-18 DroID_v2018_08 Drer\ttll12 - Cele\ttll-12 Xtro\ttll12 Mmus\Ttll12 Hsap\TTLL12 viable FBgn0004928 l(3)mbn2 lethal (3) malignant blood neoplasm 2 http://flybase.org/reports/FBgn0004928 - gene - - - "l(3)mbn-2, l(3)mbn2" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0020582 anon-59Cc anon-59Cc http://flybase.org/reports/FBgn0020582 - gene - - - anon-59Cc - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0053435 5SrRNA:CR33435 5SrRNA:CR33435 http://flybase.org/reports/FBgn0053435 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33435, 5SrRNA:CR33435" - CR33435 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0016058 rtg rotated genitalia http://flybase.org/reports/FBgn0016058 - gene - - - rtg - - 27-Aug-18 DroID_v2018_08 - - - - - - visible genitalia FBgn0264605 CG43954 - http://flybase.org/reports/FBgn0264605 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of membrane ; GO:0016021 | inferred from sequence model CG43954 - CG43954 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265493 BG01887 - http://flybase.org/reports/FBgn0265493 gene - - - BG01887 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262227 mir-991 mir-991 stem loop http://flybase.org/reports/FBgn0262227 miRNA_gene - - - "dme-mir-991, mir-991, CR42934, miR-991" - CR42934 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0052485 CG32485 - http://flybase.org/reports/FBgn0052485 protein_coding_gene Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab2 - Golgi apparatus ; GO:0005794 | inferred from direct assay "CG2159, CG32485" "IPR001251:CRAL-TRIO lipid binding domain, IPR011074:CRAL/TRIO, N-terminal domain" CG32485 27-Aug-18 DroID_v2018_08 Drer\mospd2 "Scer\PDR17, Scer\PDR16, Scer\CSR1" "Cele\T03F7.7, Cele\hpo-28, Cele\C34C12.6" - Mmus\Mospd2 Hsap\MOSPD2 viable FBgn0259918 inaF-B inaF-B http://flybase.org/reports/FBgn0259918 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with trp calcium channel regulator activity ; GO:0005246 | inferred from mutant phenotype response to light stimulus ; GO:0009416 | inferred from mutant phenotype regulation of membrane potential in photoreceptor cell ; GO:0016057 | inferred from mutant phenotype rhabdomere ; GO:0016028 | inferred from direct assay inaD signaling complex ; GO:0016027 | inferred from physical interaction with inaD inferred from physical interaction with trp rhabdomere membrane ; GO:0033583 | inferred from direct assay "inaF-B, CG42447, inaF, INAF, InaF, INAF-B" "IPR029162:TRP-interacting helix, InaF motif" CG42447 27-Aug-18 DroID_v2018_08 - - - - - - neurophysiology defective photoreceptor cell FBgn0262908 sax::Agam\sax - http://flybase.org/reports/FBgn0262908 engineered_fusion_gene - - - sax::Agam\sax - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001434 l(1)7Ad lethal (1) 7Ad http://flybase.org/reports/FBgn0001434 - gene - - - "l(1)jnR4, jnR4, l(1)7Ad" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" "genitalia,male,wing,wing disc,mesothoracic leg disc" FBgn0035247 metl methyltransferase-like http://flybase.org/reports/FBgn0035247 protein_coding_gene S-adenosylmethionine-dependent methyltransferase activity ; GO:0008757 | inferred from sequence or structural similarity with EMBL:BC006985 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon-EST:Posey109, CG13929, metl" "IPR029063:S-adenosyl-L-methionine-dependent methyltransferase, IPR026113:Methyltransferase-like" CG13929 27-Aug-18 DroID_v2018_08 "Drer\mettl6, Drer\mettl8, Drer\mettl2a" Scer\ABP140 "Cele\ZK1058.5, Cele\metl-2" "Xtro\mettl2b, Xtro\mettl6" "Mmus\Mettl2, Mmus\Mettl6, Mmus\Mettl8" "Hsap\METTL2A, Hsap\METTL2B, Hsap\METTL8, Hsap\METTL6" "wild-type,viable" FBgn0051438 CheB93b Chemosensory protein B 93b http://flybase.org/reports/FBgn0051438 protein_coding_gene lipid binding ; GO:0008289 | inferred from sequence alignment with HGNC:14537 detection of pheromone ; GO:0043695 | inferred from expression pattern sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with CheB42a extracellular region ; GO:0005576 | inferred from sequence model extracellular space ; GO:0005615 | inferred from sequence or structural similarity with CheB42a "CG31438, CheB93b" "IPR006601:Uncharacterised protein family DM11, Drosophila melanogaster" CG31438 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0062442 Cisd2 CDGSH iron sulfur domain 2 http://flybase.org/reports/FBgn0062442 protein_coding_gene "2 iron, 2 sulfur cluster binding ; GO:0051537 | inferred from electronic annotation with InterPro:IPR006622, InterPro:IPR018967, InterPro:IPR019610 molecular_function ; GO:0003674 | no biological data available" biological_process ; GO:0008150 | no biological data available "intracellular membrane-bounded organelle ; GO:0043231 | inferred from electronic annotation with InterPro:IPR006622, InterPro:IPR018967, InterPro:IPR019610 cellular_component ; GO:0005575 | no biological data available" "BcDNA:RE49709, CG1458, MitoNEET, Cisd2, cisd2, dWFS2" "IPR018967:Iron sulphur-containing domain, CDGSH-type, IPR019610:Iron sulphur domain-containing, mitoNEET, N-terminal" CG1458 27-Aug-18 DroID_v2018_08 "Drer\zgc:110843, Drer\cisd2, Drer\cisd1" - Cele\cisd-1 "Xtro\cisd2, Xtro\cisd1" "Mmus\Cisd1, Mmus\Cisd2" "Hsap\CISD2, Hsap\CISD1" viable FBgn0266210 lncRNA:CR44905 - http://flybase.org/reports/FBgn0266210 non_protein_coding_gene - - - CR44905 - CR44905 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0041756 eth-as314 eth-as314 http://flybase.org/reports/FBgn0041756 gene - - - "eth[as]314, eth-as314" - - 27-Aug-18 DroID_v2018_08 - - - - - - "chemical sensitive,recessive" FBgn0028391 anon-50ABc anon-50ABc http://flybase.org/reports/FBgn0028391 gene - - - "C, anon-50ABc" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0027182 l(2)60A-L lethal (2) 60A-L http://flybase.org/reports/FBgn0027182 - gene - - - l(2)60A-L - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0053178 CG33178 - http://flybase.org/reports/FBgn0053178 protein_coding_gene glutathione transferase activity ; GO:0004364 | inferred from sequence or structural similarity with MGI:MGI:1913850 glutathione metabolic process ; GO:0006749 | inferred from sequence or structural similarity with MGI:MGI:1913850 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with MGI:MGI:1913850 "CG5579, BcDNA:RH14671, CG33178" "IPR001129:Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein, IPR023352:Membrane associated eicosanoid/glutathione metabolism-like domain" CG33178 27-Aug-18 DroID_v2018_08 "Drer\mgst1.1, Drer\mgst1.2, Drer\ptges" - - "Xtro\mgst1, Xtro\ptges" "Mmus\Ptges, Mmus\Mgst1" "Hsap\PTGES, Hsap\MGST1" viable FBgn0266619 asRNA:CR45126 - http://flybase.org/reports/FBgn0266619 non_protein_coding_gene - - - CR45126 - CR45126 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264678 lncRNA:CR43963 - http://flybase.org/reports/FBgn0264678 non_protein_coding_gene - - - CR43963 - CR43963 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065647 l(2)SH0749 lethal (2) SH0749 http://flybase.org/reports/FBgn0065647 gene - - - "l(2)SH0749, l(2)SH2 0749" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0261574 kug kugelei http://flybase.org/reports/FBgn0261574 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR002126, InterPro:IPR015919, InterPro:IPR018097 cell adhesion molecule binding ; GO:0050839 | inferred from sequence or structural similarity calcium ion binding ; GO:0005509 | inferred from sequence model receptor activity ; GO:0004872 | inferred from sequence or structural similarity" homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from electronic annotation with InterPro:IPR002126 hindgut morphogenesis ; GO:0007442 | inferred from mutant phenotype epithelium development ; GO:0060429 | inferred from mutant phenotype cell-cell adhesion mediated by cadherin ; GO:0044331 | inferred from sequence model defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype establishment of planar polarity of follicular epithelium ; GO:0042247 | inferred from mutant phenotype calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0016339 | inferred from sequence or structural similarity germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype growth of a germarium-derived egg chamber ; GO:0007295 | inferred from mutant phenotype foregut morphogenesis ; GO:0007440 | inferred from mutant phenotype positive regulation of innate immune response ; GO:0045089 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype salivary gland development ; GO:0007431 | inferred from mutant phenotype negative regulation of imaginal disc growth ; GO:0045571 | traceable author statement homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from sequence or structural similarity open tracheal system development ; GO:0007424 | inferred from mutant phenotype establishment or maintenance of actin cytoskeleton polarity ; GO:0030950 | inferred from mutant phenotype integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity basal plasma membrane ; GO:0009925 | inferred from direct assay focal adhesion ; GO:0005925 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "fat2, RE-A, kug, ftl, CG7749, DCad76E, Cad76E, CT23445, Ftl, kugel" "IPR018097:EGF-like calcium-binding, conserved site, IPR000152:EGF-type aspartate/asparagine hydroxylation site, IPR000742:EGF-like domain, IPR001791:Laminin G domain, IPR001881:EGF-like calcium-binding domain, IPR002126:Cadherin, IPR013032:EGF-like, conserved site, IPR015919:Cadherin-like, IPR020894:Cadherin conserved site, IPR013320:Concanavalin A-like lectin/glucanase domain" CG7749 27-Aug-18 DroID_v2018_08 "Drer\dchs1b, Drer\si:dkey-22o22.2, Drer\si:ch211-186j3.6, Drer\fat2, Drer\dchs1a, Drer\cdh23, Drer\fat1a, Drer\dchs2, Drer\fat3a, Drer\fat1b, Drer\LOC568600" - "Cele\cdh-1, Cele\fmi-1, Cele\cdh-4, Cele\hmr-1" "Xtro\fat1, Xtro\fat4, Xtro\dchs2" "Mmus\Fat4, Mmus\Fat2, Mmus\Fat3, Mmus\Cdh23, Mmus\Dchs1, Mmus\Fat1" "Hsap\CDH23, Hsap\DLK2, Hsap\FAT3, Hsap\FAT1, Hsap\FAT2, Hsap\DCHS2, Hsap\FAT4, Hsap\DCHS1" FBgn0265790 lncRNA:CR44579 - http://flybase.org/reports/FBgn0265790 non_protein_coding_gene - - - CR44579 - CR44579 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051513 CG31513 - http://flybase.org/reports/FBgn0051513 protein_coding_gene - - - CG31513 - - 27-Aug-18 DroID_v2018_08 - - - - - - DRSC23522 K -0.00125279 -0.285870801 -0.528721533 0.850536889 1.842946422 -0.650106921 FBgn0060948 l(3)S037901 lethal (3) S037901 http://flybase.org/reports/FBgn0060948 gene - - - "0379/01, l(3)S037901" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0036198 crim crimpled http://flybase.org/reports/FBgn0036198 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "liquid clearance, open tracheal system ; GO:0035002 | inferred from mutant phenotype septate junction assembly ; GO:0019991 | inferred from mutant phenotype regulation of tube size, open tracheal system ; GO:0035151 | inferred from mutant phenotype" septate junction ; GO:0005918 | inferred from direct assay "CG6038, crim, Crim" - CG6038 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible" "embryonic/larval dorsal trunk,trichogen cell" FBgn0001770 l(1)M41 lethal (1) M41 http://flybase.org/reports/FBgn0001770 - gene - - - l(1)M41 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0260605 2L1561 - http://flybase.org/reports/FBgn0260605 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L1561 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0024361 Tsp2A Tetraspanin 2A http://flybase.org/reports/FBgn0024361 - protein_coding_gene "protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q0KHY3,UniProtKB:Q9VW87" establishment of endothelial intestinal barrier ; GO:0090557 | inferred from mutant phenotype establishment of endothelial barrier ; GO:0061028 | inferred from mutant phenotype cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 smooth septate junction assembly ; GO:0090528 | inferred from mutant phenotype apicolateral plasma membrane ; GO:0016327 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 smooth septate junction ; GO:0005920 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "EG:8D8.7, CG11415, D8.7, Dm.Tsp2A, Tsp2A, tsp2A" "IPR018499:Tetraspanin/Peripherin, IPR000301:Tetraspanin, IPR008952:Tetraspanin, EC2 domain" CG11415 27-Aug-18 DroID_v2018_08 "Drer\tspan12, Drer\tspan11, Drer\cd151l" - Cele\tsp-20 Xtro\tspan2 "Mmus\Tspan11, Mmus\Tspan12, Mmus\Cd151" "Hsap\TSPAN12, Hsap\CD151, Hsap\TSPAN11" FBgn0263457 asRNA:CR43480 - http://flybase.org/reports/FBgn0263457 non_protein_coding_gene - - - CR43480 - CR43480 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030060 CG2004 - http://flybase.org/reports/FBgn0030060 protein_coding_gene - - - CG2004 "IPR015897:CHK kinase-like, IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain" CG2004 27-Aug-18 DroID_v2018_08 - - "Cele\T16G1.3, Cele\F49C12.7, Cele\H37A05.2, Cele\C29F7.2, Cele\H06H21.8, Cele\nhr-246, Cele\E02C12.10, Cele\F59B1.8, Cele\C29F7.1, Cele\E02C12.6, Cele\E02C12.9, Cele\E02C12.8, Cele\F59B1.10, Cele\dhs-27, Cele\Y45G12C.4, Cele\F56A4.5" - - - viable FBgn0263627 asRNA:CR43636 - http://flybase.org/reports/FBgn0263627 non_protein_coding_gene - - - CR43636 - CR43636 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000211 bra breakage during anaphase http://flybase.org/reports/FBgn0000211 - gene - - - bra - - 27-Aug-18 DroID_v2018_08 - - - - - - mitotic cell cycle defective FBgn0002915 mc-44A mc-44A http://flybase.org/reports/FBgn0002915 - gene - - - "Myc, Dmmyc, Dmc, mc-44A" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032894 CG14402 - http://flybase.org/reports/FBgn0032894 protein_coding_gene - - - "BcDNA:AT08210, CG14402" - CG14402 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC02386 I 1.739232661 -0.122428543 0.540751925 -0.371056164 0.056215841 0.608063791 FBgn0082968 snoRNA:Psi28S-3316e snoRNA:Psi28S-3316e http://flybase.org/reports/FBgn0082968 snoRNA_gene - - - "snoRNA:Psi28S-3316e, Psi28S-3316e, psi28S-3316e, CR34554" - CR34554 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0010793 l(3)03077 lethal (3) 03077 http://flybase.org/reports/FBgn0010793 - gene - - - l(3)03077 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0011090 l(1)Q50 lethal (1) Q50 http://flybase.org/reports/FBgn0011090 FBgn0010210 gene - - - l(1)Q50 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0267269 lncRNA:TS11 long noncoding RNA: testis-specific 11 http://flybase.org/reports/FBgn0267269 non_protein_coding_gene - - - "CR45705, lncRNA:TS11, lncRNA:TS19, lncRNA:TS21" - CR45705 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051673 CG31673 - http://flybase.org/reports/FBgn0051673 protein_coding_gene "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor ; GO:0016616 | inferred from electronic annotation with InterPro:IPR006139 NAD binding ; GO:0051287 | inferred from electronic annotation with InterPro:IPR006139, InterPro:IPR006140" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006139, InterPro:IPR006140" - "CG9332, BcDNA:LD14730, CG31673, CCG31673" "IPR006139:D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain, IPR006140:D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain, IPR016040:NAD(P)-binding domain, IPR029753:D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site" CG31673 27-Aug-18 DroID_v2018_08 "Drer\zgc:136493, Drer\mthfd2, Drer\grhpra, Drer\grhprb, Drer\mthfd2l" "Scer\SER3, Scer\YGL185C, Scer\YPL113C, Scer\SER33, Scer\FDH1, Scer\GOR1" - "Xtro\grhpr.2, Xtro\mthfd2l, Xtro\grhpr.1, Xtro\mthfd2" "Mmus\Grhpr, Mmus\Mthfd2l, Mmus\Mthfd2" "Hsap\GRHPR, Hsap\MTHFD2, Hsap\MTHFD2L" viable FBgn0001464 l(1)7Ee lethal (1) 7Ee http://flybase.org/reports/FBgn0001464 - gene - - - l(1)7Ee - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0260569 MENE-MM15 - http://flybase.org/reports/FBgn0260569 gene - - - MENE-MM15 - - 27-Aug-18 DroID_v2018_08 - - - - - - "hyperplasia,somatic clone" "eye disc,somatic clone" FBgn0005310 ms(1)RD33 male sterile (1) RD33 http://flybase.org/reports/FBgn0005310 - gene - - - ms(1)RD33 - - 27-Aug-18 DroID_v2018_08 - - - - - - male sterile "spermatocyte,spermatid" FBgn0083065 rpn rantanplan http://flybase.org/reports/FBgn0083065 gene - - - rpn - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0070005 BG01526 BG01526 http://flybase.org/reports/FBgn0070005 gene - - - BG01526 - - 27-Aug-18 DroID_v2018_08 - - - - - - stress response defective FBgn0260088 2L0028 - http://flybase.org/reports/FBgn0260088 gene - - - 2L0028 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" "embryonic/larval dorsal trunk,somatic clone" FBgn0002545 lf little fly http://flybase.org/reports/FBgn0002545 - gene - - - "12, lT2-14a, lN5, l152, 9, l(1)19Ee, lf" - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,reduced,fertile,visible,lethal,recessive" adult abdomen FBgn0046650 anon-38D.15 anon-38D.15 http://flybase.org/reports/FBgn0046650 gene - - - "38D.15, anon-38D.15" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005031 E(M99E) Enhancer of Minute(3)99E http://flybase.org/reports/FBgn0005031 - gene - - - "E(M3g), E(M99E)" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259344 C478 - http://flybase.org/reports/FBgn0259344 gene - - - C478 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing vein,wing,chaeta" FBgn0051427 CR31427 - http://flybase.org/reports/FBgn0051427 pseudogene_attribute metallopeptidase activity ; GO:0008237 | inferred from electronic annotation with InterPro:IPR014782 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR014782 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001930 - "CG11955, CG31427, CR31427" "IPR001930:Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR014782:Peptidase M1, membrane alanine aminopeptidase, N-terminal" CR31427 27-Aug-18 DroID_v2018_08 "Drer\erap2, Drer\enpep, Drer\si:ch211-149p5.1, Drer\erap1b, Drer\lnpep, Drer\npepps, Drer\si:ch211-276a23.5, Drer\si:ch211-198g19.1, Drer\anpepb, Drer\si:ch211-106j24.1, Drer\anpepa, Drer\erap1a" "Scer\APE2, Scer\AAP1, Scer\TMA108" "Cele\T07F10.1, Cele\Y53F4B.20, Cele\AC3.5, Cele\T12E12.6, Cele\R03G8.6, Cele\pam-1, Cele\Y67D8C.9, Cele\Y42A5A.1, Cele\VB0395L.1, Cele\F49B2.6, Cele\T16G12.1, Cele\R03G8.4, Cele\mnp-1" "Xtro\erap1, Xtro\npepps, Xtro\lnpep, Xtro\lvrn, Xtro\anpep, Xtro\enpep" "Mmus\Anpep, Mmus\Lnpep, Mmus\Lvrn, Mmus\Enpep, Mmus\Trhde, Mmus\Npepps, Mmus\Erap1" "Hsap\TRHDE, Hsap\NPEPPS, Hsap\LNPEP, Hsap\LVRN, Hsap\ANPEP, Hsap\ERAP1, Hsap\ENPEP, Hsap\ERAP2" DRSC22675 K -0.077291304 0.39392392 -0.016155036 0.298486407 1.87596726 -0.184063301 FBgn0013700 mt:tRNA:Met-CAT mitochondrial transfer RNA:Methionine-CAT http://flybase.org/reports/FBgn0013700 FBgn0002867 tRNA_gene - - - "CR34062, tRNA[Met], tRNA[f-met], tRNA-Met, mtdbD00006294, mt:tRNA:Met-CAT, mt:tRNA:M" - CR34062 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0003558 Su(er) Suppressor of erupt http://flybase.org/reports/FBgn0003558 - gene - - - Su(er) - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060550 l(3)S098502 lethal (3) S098502 http://flybase.org/reports/FBgn0060550 gene - - - "0985/02, l(3)S098502" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0266242 lncRNA:CR44937 - http://flybase.org/reports/FBgn0266242 non_protein_coding_gene - - - "CR44937, lincRNA.733" - CR44937 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0029508 Tsp42Ea Tetraspanin 42Ea http://flybase.org/reports/FBgn0029508 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from sequence model "CG18817, Q9U3V4, CG3364, CG18742, Dm.Tsp42Ea, GH05668, BcDNA:GH05668, BcDNA:GM15292, Tsp42Ea" "IPR018499:Tetraspanin/Peripherin, IPR000301:Tetraspanin, IPR008952:Tetraspanin, EC2 domain" CG18817 27-Aug-18 DroID_v2018_08 Drer\cd63 - "Cele\tsp-1, Cele\tsp-3, Cele\tsp-7, Cele\tsp-14, Cele\tsp-2" Xtro\cd63 Mmus\Cd63 Hsap\CD63 FBgn0005037 Est-9 Esterase 9 http://flybase.org/reports/FBgn0005037 - gene - - - "EST-9, EST9, Est9, Est-9" - - 27-Aug-18 DroID_v2018_08 - - - - - - electrophoretic variant FBgn0005018 dk dark on 3 http://flybase.org/reports/FBgn0005018 - gene - - - dk - - 27-Aug-18 DroID_v2018_08 - - - - - - eye color defective pigment cell FBgn0263034 CG43329 - http://flybase.org/reports/FBgn0263034 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43329, CG12377" - CG43329 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0061035 l(3)S023941a lethal (3) S023941a http://flybase.org/reports/FBgn0061035 gene - - - "0239/41, l(3)S023941a" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0003987 vnl venula http://flybase.org/reports/FBgn0003987 - gene - - - vnl - - 27-Aug-18 DroID_v2018_08 - - - - - - wing vein FBgn0000607 E(w[a]) Enhancer of white-apricot http://flybase.org/reports/FBgn0000607 - gene - - - E(w[a]) - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage,female sterile" FBgn0000881 fs(1)M79 female sterile (1) M79 http://flybase.org/reports/FBgn0000881 - gene - - - fs(1)M79 - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive,lethal,maternal effect" FBgn0032798 CG10132 - http://flybase.org/reports/FBgn0032798 protein_coding_gene - - microtubule associated complex ; GO:0005875 | inferred from direct assay CG10132 "IPR001680:WD40 repeat, IPR007111:NACHT nucleoside triphosphatase, IPR011047:Quinoprotein alcohol dehydrogenase-like superfamily, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR019775:WD40 repeat, conserved site" CG10132 27-Aug-18 DroID_v2018_08 - - Cele\T05C3.2 - Mmus\Ttc41 Hsap\NWD1 viable FBgn0259604 B1514 - http://flybase.org/reports/FBgn0259604 gene - - - B1514 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible wing FBgn0067897 IM7 Immune induced molecule 7 http://flybase.org/reports/FBgn0067897 gene - defense response ; GO:0006952 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay "DIM 7, IM7" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265707 lncRNA:CR44514 - http://flybase.org/reports/FBgn0265707 non_protein_coding_gene - - - "incRNA.404, CR44514, lincRNA.404" - CR44514 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0015492 l(3)65ACb lethal (3) 65ACb http://flybase.org/reports/FBgn0015492 - gene - - - "II, l(3)65ACb" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0032414 CG17211 - http://flybase.org/reports/FBgn0032414 protein_coding_gene integrin binding ; GO:0005178 | inferred from sequence or structural similarity with tnc epithelial tube morphogenesis ; GO:0060562 | inferred from sequence or structural similarity with tnc extracellular matrix ; GO:0031012 | inferred from sequence or structural similarity with tnc CG17211 IPR001007:VWFC domain CG17211 27-Aug-18 DroID_v2018_08 "Drer\scaf11, Drer\scaf1, Drer\phrf1" Scer\BMT6 - - "Mmus\Scaf11, Mmus\Scaf1, Mmus\Phrf1" "Hsap\SCAF1, Hsap\PHRF1, Hsap\SCAF11" FBgn0002682 mat(2)twg maternal effect twisted gastrulation http://flybase.org/reports/FBgn0002682 - gene - - - mat(2)twg - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002295 l(3)80Ff lethal (3) 80Ff http://flybase.org/reports/FBgn0002295 - gene - - - "l4B, l(3)Lh4B, l(3)80Ff, 80Ff" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0001500 l(1)10Cc lethal (1) 10Cc http://flybase.org/reports/FBgn0001500 - gene - - - "L20, HA10, HA-10, l(1)L20, l(1)10Cc" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,cell lethal,germline clone,lethal - all die before end of larval stage,some die during larval stage" FBgn0004744 l(3)85Fa lethal (3) 85Fa http://flybase.org/reports/FBgn0004744 - gene - - - l(3)85Fa - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0053255 CR33255 - http://flybase.org/reports/FBgn0053255 pseudogene_attribute - - - "CG33255, CR33255" - CR33255 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265370 lncRNA:CR44311 - http://flybase.org/reports/FBgn0265370 non_protein_coding_gene - - - "CR44311, lincRNA.26" - CR44311 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065636 l(2)SH0769 lethal (2) SH0769 http://flybase.org/reports/FBgn0065636 gene - - - "l(2)SH0769, l(2)SH2 0769" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0001937 l(2)25Fc lethal (2) 25Fc http://flybase.org/reports/FBgn0001937 - gene - - - "l(2)gdh-15, l(2)25Fc" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0263469 snoRNA:SC35-b - http://flybase.org/reports/FBgn0263469 snoRNA_gene - - - snoRNA:SC35-b - CR43584 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002273 l(3)70Aa lethal (3) 70Aa http://flybase.org/reports/FBgn0002273 - gene - - - "l(3)ZF1, l(3)70Aa" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0013269 Fkbp39 FK506-binding protein 1 http://flybase.org/reports/FBgn0013269 - protein_coding_gene peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from electronic annotation with InterPro:IPR026257 juvenile hormone response element binding ; GO:0070594 | inferred from direct assay FK506 binding ; GO:0005528 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Chd64 histone peptidyl-prolyl isomerization ; GO:0000412 | inferred from electronic annotation with InterPro:IPR026257 negative regulation of macroautophagy ; GO:0016242 | inferred from mutant phenotype negative regulation of autophagy ; GO:0010507 | inferred from mutant phenotype juvenile hormone mediated signaling pathway ; GO:0035626 | inferred from mutant phenotype nucleolus ; GO:0005730 | inferred from electronic annotation with InterPro:IPR026257 microtubule associated complex ; GO:0005875 | inferred from direct assay heterochromatin ; GO:0000792 | inferred from direct assay "IFK506-bp1, CG6226, FK506bp1, FKBP39, FKbp39, FK506-bp1" "IPR001179:FKBP-type peptidyl-prolyl cis-trans isomerase domain, IPR023566:Peptidyl-prolyl cis-trans isomerase, FKBP-type, IPR026257:FK506-binding protein" CG6226 27-Aug-18 DroID_v2018_08 "Drer\fkbp1ab, Drer\fkbp11, Drer\fkbp1b, Drer\fkbp9, Drer\fkbp10b, Drer\fkbp14, Drer\fkbp1aa, Drer\fkbp2, Drer\fkbp7, Drer\fkbp10a, Drer\si:ch73-199g24.2, Drer\si:ch211-208h16.4" "Scer\FPR4, Scer\FPR3" "Cele\fkb-3, Cele\fkb-2, Cele\fkb-5, Cele\fkb-4" "Xtro\fkbp14, Xtro\fkbp7, Xtro\fkbp3, Xtro\fkbp1b, Xtro\fkbp9, Xtro\fkbp15, Xtro\fkbp10" "Mmus\Fkbp3, Mmus\Fkbp2, Mmus\Fkbp11, Mmus\Fkbp14, Mmus\Fkbp1a, Mmus\Fkbp15, Mmus\Fkbp1b, Mmus\Fkbp10, Mmus\Fkbp7, Mmus\Fkbp9" "Hsap\FKBP15, Hsap\FKBP7, Hsap\FKBP11, Hsap\FKBP9, Hsap\FKBP10, Hsap\FKBP1B, Hsap\FKBP2, Hsap\FKBP3, Hsap\FKBP14" " embryonic stage -- adult stage , adult stage && oogenesis stage , adult stage " " ovary

,

ubiquitous " "visible,partially lethal - majority die,some die during pupal stage,viable,fertile" "embryonic/larval fat body,somatic clone,trichogen cell,mesothoracic tergum" DRSC16667 EK 1.201663215 0.791282378 1.69799848 -0.397210135 2.584880987 0.550019966 FBgn0069912 CR40474 - http://flybase.org/reports/FBgn0069912 non_protein_coding_gene - - - CR40474 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005191 l(2)S51 lethal of Seto 51 http://flybase.org/reports/FBgn0005191 - gene - - - l(2)S51 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of prepupal stage,some die during prepupal stage,recessive" FBgn0020932 Est-B Est-B http://flybase.org/reports/FBgn0020932 - gene - - - Est-B - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000023 acclinal-wing acclinal wing http://flybase.org/reports/FBgn0000023 - gene - - - "acc, acclinal-wing" - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive,viable,good,fertile,flightless" wing FBgn0041129 l(2)45Ag lethal (2) 45Ag http://flybase.org/reports/FBgn0041129 gene - - - l(2)45Ag - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0259710 CG42364 - http://flybase.org/reports/FBgn0259710 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG15675, CG42364" - CG42364 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0052212 CG32212 - http://flybase.org/reports/FBgn0052212 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32212 - CG32212 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060980 l(3)S028401 lethal (3) S028401 http://flybase.org/reports/FBgn0060980 gene - - - "0284/01, l(3)S028401" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0001828 l(1)TS56 lethal (1) TS56 http://flybase.org/reports/FBgn0001828 - gene - - - "l(1)TS-56, l(1)TS56" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" "embryonic/larval tracheal system,embryonic segment" FBgn0025616 CG13359 - http://flybase.org/reports/FBgn0025616 - protein_coding_gene - - - "EG:34F3.9, CG13359" "IPR032675:Leucine-rich repeat domain, L domain-like" CG13359 27-Aug-18 DroID_v2018_08 - Scer\MSC1 "Cele\dur-1, Cele\lea-1" - - Hsap\EFCAB13 viable FBgn0031940 CG7214 - http://flybase.org/reports/FBgn0031940 protein_coding_gene - positive regulation of NFAT protein import into nucleus ; GO:0051533 | inferred from mutant phenotype - CG7214 IPR031874:Adult cuticle protein 1 CG7214 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" DRSC03028 IEK 1.479609521 -2.499599158 1.555861842 1.444557231 1.885904257 0.032893018 FBgn0015766 Msr-110 Msr-110 http://flybase.org/reports/FBgn0015766 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of membrane ; GO:0016021 | inferred from sequence model "CG10596, Msr-110" IPR022207:Genetic suppressor element-like CG10596 27-Aug-18 DroID_v2018_08 - - - - - - " embryonic stage | stage 11 , embryonic stage | stage 11 | late , embryonic stage | 12-18 hr , embryonic stage | stage 11 | early , larval stage " " embryonic/larval pharynx

, inclusive hindgut primordium

, median tooth

, posterior spiracle primordium

, anal pad | presumptive

, stomodeum

, antenno-maxillary complex | presumptive

, imaginal disc

, epidermis

" viable FBgn0037412 Osi4 Osiris 4 http://flybase.org/reports/FBgn0037412 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of plasma membrane ; GO:0005887 | inferred from sequence model "Osi4, CG10303" IPR012464:Protein of unknown function DUF1676 CG10303 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0023530 CG3740 - http://flybase.org/reports/FBgn0023530 - protein_coding_gene - neuromuscular process ; GO:0050905 | inferred from genetic interaction with CG11671 - "EG:171E4.4, CG3740" IPR033369:Protein C19orf12 homologue CG3740 27-Aug-18 DroID_v2018_08 "Drer\zgc:101715, Drer\si:ch211-260e23.7, Drer\zgc:112052, Drer\si:ch211-260e23.8" - - Xtro\c19orf12 Mmus\1600014C10Rik Hsap\C19orf12 viable FBgn0058317 CG40317 - http://flybase.org/reports/FBgn0058317 protein_coding_gene - - - CG40317 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266781 lncRNA:CR45246 - http://flybase.org/reports/FBgn0266781 non_protein_coding_gene - - - CR45246 - CR45246 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262017 CG42830 - http://flybase.org/reports/FBgn0262017 protein_coding_gene transcription cofactor activity ; GO:0003712 | inferred from sequence or structural similarity with akirin positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from sequence or structural similarity with akirin nucleus ; GO:0005634 | inferred from sequence or structural similarity with akirin "CG7527, CG42830, anon-AE003656.1" IPR024132:Akirin CG42830 27-Aug-18 DroID_v2018_08 "Drer\akirin1, Drer\akirin2" - Cele\akir-1 "Xtro\akirin2, Xtro\akirin1" "Mmus\Akirin1, Mmus\Akirin2" "Hsap\AKIRIN1, Hsap\AKIRIN2" FBgn0028013 l(3)S108310a lethal (3) S108310a http://flybase.org/reports/FBgn0028013 gene - - - "1083/10, l(3)S108310, l(3)S108310a" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0022216 l(2)k03610 lethal (2) k03610 http://flybase.org/reports/FBgn0022216 - gene - - - l(2)k03610 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0016897 l(3)64Cg lethal (3) 64Cg http://flybase.org/reports/FBgn0016897 - gene - - - l(3)64Cg - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0036138 CG14143 - http://flybase.org/reports/FBgn0036138 protein_coding_gene - - - "CG14143, chr3L_11128040_11128584.0" - CG14143 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065513 l(2)SH1164 lethal (2) SH1164 http://flybase.org/reports/FBgn0065513 gene - - - "l(2)SH1164, l(2)SH2 1164" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0004133 blow blown fuse http://flybase.org/reports/FBgn0004133 - protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with rols mesoderm development ; GO:0007498 | inferred from expression pattern myoblast fusion ; GO:0007520 | traceable author statement myoblast fusion ; GO:0007520 | inferred from mutant phenotype actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype podosome ; GO:0002102 | colocalizes_with inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay cytoplasm ; GO:0005737 | non-traceable author statement "CG1363, l(2)43Eb, Blow, blow" "IPR001849:Pleckstrin homology domain, IPR011993:PH domain-like" CG1363 27-Aug-18 DroID_v2018_08 "Drer\zgc:92360, Drer\adap2" "Scer\GTS1, Scer\AGE2" "Cele\git-1, Cele\F59A2.5" - "Mmus\Adap1, Mmus\Adap2" "Hsap\CA3, Hsap\ADAP2, Hsap\ADAP1" " embryonic stage | stage 11-14 , embryonic stage | stage 10 " " embryonic myoblast

, mesoderm | restricted & segmentally repeated

" embryonic stage | stage 11-14 embryonic myoblast

"lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,recessive,viable" "embryonic myoblast,A1-7 dorsal acute muscle 1,myoblast,somatic muscle primordium,embryonic/larval somatic muscle,presumptive embryonic/larval muscle system,fusion competent cell" FBgn0001611 l(1)dd3 lethal (1) discs degenerate 3 http://flybase.org/reports/FBgn0001611 - gene - - - "d.deg.-3, l(1)d deg-3, l(1)d.deg.-3, l(1)d.deg.3, l(1)dd3" - - 27-Aug-18 DroID_v2018_08 - - - - - - "mitotic cell cycle defective,cell lethal,germline clone,lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal - all die before end of larval stage,some die during larval stage" "cell cycle,imaginal disc,cell autonomous,somatic clone,embryonic/larval brain,embryonic/larval optic lobe,foregut imaginal ring,embryonic/larval salivary gland,gonad,male" FBgn0260016 bha bahia http://flybase.org/reports/FBgn0260016 gene - - - bha - - 27-Aug-18 DroID_v2018_08 - - - - - - viable "chorion,dorsal appendage,chorion | germline clone" FBgn0262888 asRNA:CR43243 - http://flybase.org/reports/FBgn0262888 non_protein_coding_gene - - - "CG43243, CR43243" - CR43243 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0063382 snoRNA:U29:54Ed snoRNA:U29:54Ed http://flybase.org/reports/FBgn0063382 snoRNA_gene - - - "U29snoRNA, CR32895, snoRNA:U29:54Ed, DmSnR71b" - CR32895 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0016784 anon-91Ab anon-91Ab http://flybase.org/reports/FBgn0016784 - gene - - - anon-91Ab - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031023 CG14200 - http://flybase.org/reports/FBgn0031023 protein_coding_gene - - - CG14200 IPR000313:PWWP domain CG14200 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262185 mir-995 mir-995 stem loop http://flybase.org/reports/FBgn0262185 miRNA_gene - - - "mir-995, miR-995, miR-20072, 995, CR42892, dme-miR-995" - CR42892 27-Aug-18 DroID_v2018_08 - - - - - - "visible,lethal" "eye,male,wing,wing margin,1st posterior cell" FBgn0002062 l(2)40Fg lethal (2) 40Fg http://flybase.org/reports/FBgn0002062 - gene - - - "40Fg, l(2Lh)Fg, GroupVI, l(2L)D', l(2)40Fg" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0262363 CG43061 - http://flybase.org/reports/FBgn0262363 protein_coding_gene molecular_function ; GO:0003674 | no biological data available pathogenesis ; GO:0009405 | inferred from electronic annotation with InterPro:IPR012624 biological_process ; GO:0008150 | no biological data available extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR012624 cellular_component ; GO:0005575 | no biological data available CG43061 IPR012624:Conotoxin I-superfamily CG43061 27-Aug-18 DroID_v2018_08 - - - - "Mmus\Clpsl2, Mmus\Clps" "Hsap\CLPSL1, Hsap\CLPS" FBgn0037051 CG10565 - http://flybase.org/reports/FBgn0037051 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR009057 - - CG10565 "IPR001005:SANT/Myb domain, IPR001623:DnaJ domain, IPR009057:Homeobox domain-like, IPR017877:Myb-like domain, IPR032003:Ribosome-associated complex head domain" CG10565 27-Aug-18 DroID_v2018_08 "Drer\vwa9, Drer\dnajc2" Scer\ZUO1 Cele\dnj-11 "Xtro\vwa9, Xtro\dnajc2" "Mmus\Vwa9, Mmus\Dnajc2" "Hsap\DNAJB4, Hsap\DNAJC2" "viable,visible" trichogen cell DRSC11620 I 0.590226745 -2.394098507 0.608748108 0.037200972 -0.255469366 -0.102439536 FBgn0263838 lncRNA:CR43700 - http://flybase.org/reports/FBgn0263838 non_protein_coding_gene - - - CR43700 - CR43700 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031893 MICU1 Mitochondrial calcium uptake 1 http://flybase.org/reports/FBgn0031893 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 anesthesia-resistant memory ; GO:0007615 | inferred from mutant phenotype positive regulation of mitochondrial calcium ion concentration ; GO:0051561 | inferred from sequence or structural similarity with UniProtKB:Q9BPX6 medium-term memory ; GO:0072375 | inferred from mutant phenotype calcium ion transmembrane import into mitochondrion ; GO:0036444 | inferred from mutant phenotype - "CG4495, MICU1" "IPR002048:EF-hand domain, IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site" CG4495 27-Aug-18 DroID_v2018_08 "Drer\micu3a, Drer\micu1, Drer\micu3b, Drer\micu2" - Cele\micu-1 "Xtro\micu2, Xtro\micu1" "Mmus\Micu1, Mmus\Micu3, Mmus\Micu2" "Hsap\MICU1, Hsap\MICU3, Hsap\MICU2" "partially lethal - majority die,some die during pupal stage" DRSC02752 K 0.112096133 -0.310052943 -0.312297822 -0.507856105 1.961459342 -1.07381608 FBgn0011111 l(1)Q72 lethal (1) Q72 http://flybase.org/reports/FBgn0011111 FBgn0010210 gene - - - l(1)Q72 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0085241 CG34212 - http://flybase.org/reports/FBgn0085241 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34212 - CG34212 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085689 CG41558 - http://flybase.org/reports/FBgn0085689 protein_coding_gene - - - CG41558 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0086207 E(ls)3 - http://flybase.org/reports/FBgn0086207 gene - - - E(ls)3 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0010240 Lcch3 Ligand-gated chloride channel homolog 3 http://flybase.org/reports/FBgn0010240 - protein_coding_gene GABA-A receptor activity ; GO:0004890 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000435002 GABA-gated chloride ion channel activity ; GO:0022851 | inferred from direct assay "ion transport ; GO:0006811 | inferred from electronic annotation with InterPro:IPR002289, InterPro:IPR006028, InterPro:IPR006029, InterPro:IPR006201" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR006028, InterPro:IPR006201 plasma membrane ; GO:0005886 | inferred from direct assay GABA-A receptor complex ; GO:1902711 | inferred from biological aspect of ancestor with PANTHER:PTN000435002" "DmGA_b, DmGABAbeta, LCCH3, CG17336, Lcch3, CT38330" "IPR018000:Neurotransmitter-gated ion-channel, conserved site, IPR002289:Gamma-aminobutyric-acid A receptor, beta subunit, IPR006028:Gamma-aminobutyric acid A receptor/Glycine receptor alpha, IPR006029:Neurotransmitter-gated ion-channel transmembrane domain, IPR006201:Neurotransmitter-gated ion-channel, IPR006202:Neurotransmitter-gated ion-channel ligand-binding domain" CG17336 27-Aug-18 DroID_v2018_08 "Drer\gabra6a, Drer\gabrp, Drer\gabrb4, Drer\LOC100330554, Drer\gabrz, Drer\glra2, Drer\glra4b, Drer\si:dkey-155h10.3, Drer\glrba, Drer\gabrr1, Drer\glra4a, Drer\LOC561083, Drer\gabrb2, Drer\glrbb, Drer\gabra1, Drer\si:dkey-52k1.6, Drer\gabra6b, Drer\gabra5, Drer\gabrr2b, Drer\LOC562831, Drer\gabrd, Drer\glra3, Drer\LOC100001259, Drer\zgc:110204, Drer\gabrg2, Drer\gabrr3a, Drer\gabrr2a, Drer\gabrb1, Drer\gabrb3" - "Cele\lgc-41, Cele\glc-2, Cele\mod-1, Cele\lgc-37, Cele\gab-1, Cele\lgc-38, Cele\avr-15, Cele\glc-3, Cele\lgc-44, Cele\lgc-36, Cele\lgc-40, Cele\unc-49, Cele\glc-4, Cele\lgc-42, Cele\lgc-39, Cele\ggr-1, Cele\avr-14" "Xtro\gabra2, Xtro\gabrr3, Xtro\gabra6, Xtro\gabrg2, Xtro\glrb, Xtro\gabrb2, Xtro\LOC100490720, Xtro\glra3, Xtro\gabrb3, Xtro\gabrd, Xtro\gabrp, Xtro\glra2, Xtro\glra1, Xtro\gabra5" "Mmus\Glra3, Mmus\Gabrp, Mmus\Gabrg1, Mmus\Gabrb2, Mmus\Gabre, Mmus\Gabra3, Mmus\Gabra2, Mmus\Gabrg2, Mmus\Gabra1, Mmus\Glrb, Mmus\Gabrd, Mmus\Gabrr1, Mmus\Gabra5, Mmus\Glra1, Mmus\Gabrb1, Mmus\Glra4, Mmus\Gabrb3, Mmus\Gabrg3, Mmus\Gabrr3, Mmus\Gabrq, Mmus\Glra2, Mmus\Gabra6, Mmus\Gabrr2" "Hsap\GABRG3, Hsap\GABRG2, Hsap\GABRR1, Hsap\GABRP, Hsap\GLRA3, Hsap\GABRA5, Hsap\GABRB3, Hsap\GABRA2, Hsap\GABRE, Hsap\GLRB, Hsap\GLRA1, Hsap\GABRA6, Hsap\GABRG1, Hsap\GABRA1, Hsap\GABRA4, Hsap\GLRA2, Hsap\GABRR2, Hsap\GABRR3, Hsap\GABRB1, Hsap\GLRA4, Hsap\GABRQ, Hsap\GABRD, Hsap\GABRB2" viable FBgn0035789 mthl6 methuselah-like 6 http://flybase.org/reports/FBgn0035789 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity with mth cell surface receptor signaling pathway ; GO:0007166 | inferred from electronic annotation with InterPro:IPR017981 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with mth determination of adult lifespan ; GO:0008340 | inferred from sequence or structural similarity with UniProtKB:O97148 response to starvation ; GO:0042594 | inferred from sequence or structural similarity with UniProtKB:O97148 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with mth "CG16992, anon-WO0170980.128, anon-WO0170980.127, mthl6" "IPR017981:GPCR, family 2-like, IPR010596:Methuselah, N-terminal domain, IPR000832:GPCR, family 2, secretin-like, IPR022343:GCR1-cAMP receptor, IPR023311:Methuselah ectodomain, domain 2" CG16992 27-Aug-18 DroID_v2018_08 "Drer\adgrf11, Drer\adgrg6" - Cele\lat-2 Xtro\gpr157 Mmus\Adgre1 - viable FBgn0263561 mir-4984 mir-4984 stem loop http://flybase.org/reports/FBgn0263561 miRNA_gene - - - "mir-4984, dme-mir-4984, CR43546" - CR43546 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051266 CG31266 - http://flybase.org/reports/FBgn0051266 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314" - "SPH146, CG5240, CG31266" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan" CG31266 27-Aug-18 DroID_v2018_08 "Drer\try, Drer\zgc:171509, Drer\prss59.2, Drer\zmp:0000001088" - Cele\svh-1 - "Mmus\Klk14, Mmus\Klk7, Mmus\Prss54, Mmus\Prss1, Mmus\Prss3, Mmus\Klk1b21, Mmus\Prss55, Mmus\Cfd" "Hsap\KLK14, Hsap\PRSS3, Hsap\CFD, Hsap\KLK7" viable FBgn0028018 l(3)S104913b lethal (3) S104913b http://flybase.org/reports/FBgn0028018 gene - - - "1049/13, l(3)S104913, l(3)S104913b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,some die during immature adult stage" FBgn0038796 eIF3g2 eukaryotic translation initiation factor 3 subunit g2 http://flybase.org/reports/FBgn0038796 protein_coding_gene mRNA binding ; GO:0003729 | inferred from sequence or structural similarity translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity translation initiation factor activity ; GO:0003743 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000039396 translational initiation ; GO:0006413 | inferred from sequence or structural similarity regulation of cell cycle ; GO:0051726 | inferred from direct assay eukaryotic translation initiation factor 3 complex ; GO:0005852 | inferred from biological aspect of ancestor with PANTHER:PTN000039396 eukaryotic translation initiation factor 3 complex ; GO:0005852 | inferred from sequence or structural similarity "eIF3-S4, cg10881, CG10881, eIF3g2, eIF3gb" "IPR000504:RNA recognition motif domain, IPR017334:Eukaryotic translation initiation factor 3 subunit G, IPR024675:Eukaryotic translation initiation factor 3 subunit G, N-terminal, IPR034240:eIF3G, RNA recognition motif" CG10881 27-Aug-18 DroID_v2018_08 Drer\eif3g Scer\TIF35 Cele\eif-3.G Xtro\eif3g Mmus\Eif3g Hsap\EIF3G lethal DRSC28960 K -0.231662238 -0.036076986 0.322971999 0.975098108 1.819966063 0.16050251 FBgn0011221 goul goulash http://flybase.org/reports/FBgn0011221 - gene - spermatid development ; GO:0007286 | inferred from mutant phenotype - goul - - 27-Aug-18 DroID_v2018_08 - - - - - - male sterile FBgn0019821 eZ6 eZ6 http://flybase.org/reports/FBgn0019821 - gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with N cellular_component ; GO:0005575 | no biological data available eZ6 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0025382 Rab27 Rab27 http://flybase.org/reports/FBgn0025382 - protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579, InterPro:IPR005225 protein binding ; GO:0005515 | inferred from physical interaction with Rph GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11" melanosome transport ; GO:0032402 | inferred from biological aspect of ancestor with PANTHER:PTN001178482 sleep ; GO:0030431 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 positive regulation of exocytosis ; GO:0045921 | inferred from biological aspect of ancestor with PANTHER:PTN001178482 exosomal secretion ; GO:1990182 | inferred from mutant phenotype Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 synaptic vesicle ; GO:0008021 | inferred from direct assay melanosome ; GO:0042470 | inferred from biological aspect of ancestor with PANTHER:PTN001178482 synapse ; GO:0045202 | inferred from direct assay secretory granule ; GO:0030141 | inferred from biological aspect of ancestor with PANTHER:PTN001178482 "dm-Rab27, AAF45635, AAF45634, EG:80H7.4, DmRab27, CG14791, Rab27, rab27, 18543235, O76901" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG14791 27-Aug-18 DroID_v2018_08 "Drer\rab27b, Drer\rab27a" "Scer\YPT1, Scer\SEC4" Cele\aex-6 "Xtro\rab27a, Xtro\rab27b" "Mmus\Rab27a, Mmus\Rab27b" "Hsap\RAB27B, Hsap\RAB27A" "viable,fertile,sleep defective" FBgn0038039 CG5196 - http://flybase.org/reports/FBgn0038039 protein_coding_gene protein-cysteine S-palmitoyltransferase activity ; GO:0019706 | inferred from sequence or structural similarity with SGD:S000004236 protein palmitoylation ; GO:0018345 | inferred from sequence or structural similarity with SGD:S000004236 Golgi organization ; GO:0007030 | inferred from mutant phenotype endoplasmic reticulum ; GO:0005783 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay CG5196 "IPR001594:Palmitoyltransferase, DHHC domain" CG5196 27-Aug-18 DroID_v2018_08 Drer\zdhhc6 "Scer\PFA3, Scer\SWF1, Scer\ERF2, Scer\PFA4" "Cele\dhhc-6, Cele\dhhc-5" Xtro\zdhhc6 Mmus\Zdhhc6 Hsap\ZDHHC6 viable FBgn0004936 ABO-2R Abnormal Oocyte on 2R http://flybase.org/reports/FBgn0004936 - region - - - "ABO, ABO-2R" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259963 Sfp33A2 Seminal fluid protein 33A2 http://flybase.org/reports/FBgn0259963 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "Sfp33A2, CG42473" - CG42473 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002665 mat(2)ea-B maternal effect early arrest B http://flybase.org/reports/FBgn0002665 - gene - - - "mat(2)earlyPG44, mat(2)ea-B" - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage" FBgn0029001 ms(3)08724 ms(3)08724 http://flybase.org/reports/FBgn0029001 gene - - - "P1732, ms(3)08724" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262533 CR43087 - http://flybase.org/reports/FBgn0262533 pseudogene_attribute - - - CR43087 - CR43087 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267825 L Lobe http://flybase.org/reports/FBgn0267825 protein_coding_gene - negative regulation of programmed cell death ; GO:0043069 | inferred from mutant phenotype eye-antennal disc development ; GO:0035214 | inferred from mutant phenotype negative regulation of Wnt signaling pathway ; GO:0030178 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype negative regulation of JNK cascade ; GO:0046329 | inferred from mutant phenotype regulation of imaginal disc growth ; GO:0045570 | inferred from mutant phenotype cytoplasm ; GO:0005737 | non-traceable author statement cytosol ; GO:0005829 | inferred from direct assay "L, fee" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000269 ccb central complex broad http://flybase.org/reports/FBgn0000269 - gene - central complex development ; GO:0048036 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype - ccb - - 27-Aug-18 DroID_v2018_08 - - - - - - "learning defective,recessive,behavior defective,memory defective" "ellipsoid body,supernumerary,adult central complex,fan-shaped body,protocerebral bridge" FBgn0265472 Apc::Apc2 - http://flybase.org/reports/FBgn0265472 engineered_fusion_gene - - - Apc::Apc2 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263355 CG31688 - http://flybase.org/reports/FBgn0263355 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG31688, CG11019, 38C.52, 38C.49, CG18597, CG11017, CG11016, CG31688-PA" IPR001602:Uncharacterised protein family UPF0047 CG31688 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266008 lncRNA:CR44781 - http://flybase.org/reports/FBgn0266008 non_protein_coding_gene - - - CR44781 - CR44781 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0020858 fj-s four-jointed-similis http://flybase.org/reports/FBgn0020858 - gene - - - fj-s - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267120 lncRNA:CR45560 - http://flybase.org/reports/FBgn0267120 non_protein_coding_gene - - - CR45560 - CR45560 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0024509 Sec13 Secretory 13 http://flybase.org/reports/FBgn0024509 "FBgn0025715, FBgn0027897" protein_coding_gene structural molecule activity ; GO:0005198 | inferred from sequence or structural similarity with SGD:S000004198 chromatin binding ; GO:0003682 | inferred from direct assay inferred from mutant phenotype SMAD protein import into nucleus ; GO:0007184 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype ecdysone-mediated polytene chromosome puffing ; GO:0035077 | inferred from direct assay larval chitin-based cuticle development ; GO:0008363 | inferred from mutant phenotype chitin-based larval cuticle pattern formation ; GO:0035293 | inferred from mutant phenotype negative regulation of gene expression ; GO:0010629 | inferred from direct assay COPII-coated vesicle budding ; GO:0090114 | inferred from sequence or structural similarity with SGD:S000004198 NLS-bearing protein import into nucleus ; GO:0006607 | NOT inferred from mutant phenotype positive regulation of transcription initiation from RNA polymerase II promoter ; GO:0060261 | inferred from mutant phenotype cellular response to heat ; GO:0034605 | inferred from mutant phenotype chromatin ; GO:0000785 | inferred from direct assay inferred from mutant phenotype nucleoplasm ; GO:0005654 | inferred from direct assay polytene chromosome puff ; GO:0005703 | inferred from direct assay GATOR2 complex ; GO:0061700 | traceable author statement COPII vesicle coat ; GO:0030127 | inferred from sequence or structural similarity with SGD:S000004198 nuclear pore outer ring ; GO:0031080 | inferred from sequence or structural similarity with HGNC:10697 Seh1-associated complex ; GO:0035859 | inferred from direct assay Seh1-associated complex ; GO:0035859 | inferred from sequence or structural similarity with SGD:S000004198 "Dsec13, l(3)01031, CK00043, CG6773, BcDNA:LD03471, BEST:CK00043, SEC13, Sec13, sec13" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain, IPR001680:WD40 repeat" CG6773 27-Aug-18 DroID_v2018_08 Drer\sec13 Scer\SEC13 Cele\npp-20 Xtro\sec13 Mmus\Sec13 Hsap\SEC13 "lethal,recessive" FBgn0024623 l(4)102Ca lethal (4) 102Ca http://flybase.org/reports/FBgn0024623 - gene - - - l(4)102Ca - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0060929 l(3)S042016b lethal (3) S042016b http://flybase.org/reports/FBgn0060929 gene - - - "0420/16, l(3)S042016b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0265870 lncRNA:CR44659 - http://flybase.org/reports/FBgn0265870 non_protein_coding_gene - - - CR44659 - CR44659 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0026727 chs chaos http://flybase.org/reports/FBgn0026727 - gene - - - chs - - 27-Aug-18 DroID_v2018_08 - - - - - - "presumptive embryonic/larval central nervous system,commissure,longitudinal connective" FBgn0036470 EAChm Enhancer of Acetyltransferase Chameau http://flybase.org/reports/FBgn0036470 protein_coding_gene histone acetyltransferase regulator activity ; GO:0035034 | inferred from direct assay "regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype histone H3 acetylation ; GO:0043966 | inferred from direct assay" - "BcDNA:RE10167, CG13463, EAChm" - CG13463 27-Aug-18 DroID_v2018_08 - - - - - - "viable,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0011048 l(1)Q1 lethal (1) Q1 http://flybase.org/reports/FBgn0011048 FBgn0010210 gene - - - l(1)Q1 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0050197 CG30197 - http://flybase.org/reports/FBgn0050197 protein_coding_gene peptidase inhibitor activity ; GO:0030414 | inferred from electronic annotation with InterPro:IPR008197 biological_process ; GO:0008150 | no biological data available extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR008197 "BcDNA:RE05231, CG30197" IPR008197:WAP-type 'four-disulfide core' domain CG30197 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0004038 yea4 yeast 4 http://flybase.org/reports/FBgn0004038 - gene - - - yea4 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0003335 Scn Scutenick http://flybase.org/reports/FBgn0003335 - gene - - - Scn - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,visible,dominant" "scutellar bristle,ocellus,macrochaeta,eye,cold sensitive,scutellum" FBgn0036230 CG11570 - http://flybase.org/reports/FBgn0036230 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "CG11570, mlncRNA68E3" IPR002557:Chitin binding domain CG11570 27-Aug-18 DroID_v2018_08 - - Cele\dct-9 - - - "viable,fertile" FBgn0026161 tiz tiziano http://flybase.org/reports/FBgn0026161 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available tiz - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038315 CG14866 - http://flybase.org/reports/FBgn0038315 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from sequence or structural similarity with Lectin-galC1 - - CG14866 "IPR001304:C-type lectin-like, IPR016186:C-type lectin-like/link domain, IPR016187:C-type lectin fold" CG14866 27-Aug-18 DroID_v2018_08 "Drer\LOC101884413, Drer\si:ch73-361h17.1, Drer\si:ch73-111e15.1, Drer\si:dkey-61f9.1, Drer\zmp:0000000924, Drer\si:ch211-232p21.6, Drer\si:ch73-343l4.8, Drer\cd209, Drer\si:ch211-170d8.5, Drer\si:dkey-187i8.2, Drer\si:ch73-86n18.1, Drer\LOC101884526, Drer\si:ch73-343l4.2, Drer\LOC100331140, Drer\illr1, Drer\si:ch211-214k5.3, Drer\zgc:174904, Drer\LOC100007376, Drer\LOC101886537, Drer\si:dkey-61f9.2, Drer\illr3, Drer\si:ch211-133n4.7, Drer\si:ch73-122g19.1, Drer\si:ch211-283g2.3, Drer\illr4, Drer\illr2, Drer\zmp:0000000937" - "Cele\clec-185, Cele\clec-160, Cele\clec-198, Cele\clec-149, Cele\C25G4.17, Cele\clec-78, Cele\clec-184, Cele\clec-202, Cele\clec-199" - "Mmus\Cd209b, Mmus\Clec4a1, Mmus\Clec4b2, Mmus\Mgl2, Mmus\Clec4n, Mmus\Asgr1, Mmus\Cd209d, Mmus\Cd207, Mmus\Cd209e, Mmus\Clec4b1, Mmus\Cd209a, Mmus\Clec4d, Mmus\Clec4a2, Mmus\Asgr2, Mmus\Clec4g, Mmus\Fcer2a, Mmus\Clec4a3, Mmus\Clec10a, Mmus\Clec4e, Mmus\Cd209f, Mmus\Cd209g, Mmus\Clec4f, Mmus\Cd209c, Mmus\Clec4a4" "Hsap\CLEC10A, Hsap\CD207, Hsap\CLEC4M, Hsap\CLEC6A, Hsap\CD209, Hsap\CLEC4E, Hsap\CLEC4A, Hsap\CLEC9A, Hsap\ASGR2, Hsap\CLEC17A, Hsap\CLEC4G, Hsap\CLEC4F, Hsap\CLEC4D, Hsap\CLEC4C, Hsap\ASGR1, Hsap\FCER2" viable FBgn0030995 CG7914 - http://flybase.org/reports/FBgn0030995 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN000452136 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001834, InterPro:IPR017927, InterPro:IPR017938" - CG7914 "IPR001834:NADH:cytochrome b5 reductase (CBR), IPR008333:Oxidoreductase, FAD-binding domain, IPR017927:Ferredoxin reductase-type FAD-binding domain, IPR017938:Riboflavin synthase-like beta-barrel" CG7914 27-Aug-18 DroID_v2018_08 "Drer\cyb5r3, Drer\cyb5r1, Drer\cyb5r2, Drer\cyb5r4, Drer\oxnad1" "Scer\CYC2, Scer\AIM33, Scer\MCR1, Scer\PGA3, Scer\CBR1" - "Xtro\cyb5r4, Xtro\cyb5r1, Xtro\oxnad1, Xtro\cyb5r2, Xtro\cyb5r3" "Mmus\Cyb5rl, Mmus\Cyb5r3, Mmus\Cyb5r1, Mmus\Cyb5r4, Mmus\Oxnad1, Mmus\Cyb5r2" "Hsap\CYB5R4, Hsap\CYB5RL, Hsap\OXNAD1, Hsap\CYB5R2, Hsap\CYB5R1, Hsap\CYB5R3" viable FBgn0033558 CG12344 - http://flybase.org/reports/FBgn0033558 protein_coding_gene extracellular ligand-gated ion channel activity ; GO:0005230 | inferred from electronic annotation with InterPro:IPR006202 chloride channel activity ; GO:0005254 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001055382 "ion transport ; GO:0006811 | inferred from electronic annotation with InterPro:IPR006028, InterPro:IPR006029, InterPro:IPR006201" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR006028, InterPro:IPR006201" "CG12344, Lcch-47C, CT23391" "IPR006028:Gamma-aminobutyric acid A receptor/Glycine receptor alpha, IPR006029:Neurotransmitter-gated ion-channel transmembrane domain, IPR006201:Neurotransmitter-gated ion-channel, IPR006202:Neurotransmitter-gated ion-channel ligand-binding domain, IPR018000:Neurotransmitter-gated ion-channel, conserved site" CG12344 27-Aug-18 DroID_v2018_08 "Drer\glra4b, Drer\glrba, Drer\glra1, Drer\glra4a, Drer\glrbb, Drer\glra2, Drer\glra3" - "Cele\lgc-38, Cele\lgc-49, Cele\unc-49" "Xtro\glra2, Xtro\glrb, Xtro\glra1, Xtro\glra3" "Mmus\Glra4, Mmus\Glrb, Mmus\Glra2, Mmus\Glra1, Mmus\Glra3" "Hsap\GLRA4, Hsap\GLRA1, Hsap\GLRA2, Hsap\GLRA3, Hsap\GLRB" "viable,fertile" FBgn0036410 CG8100 - http://flybase.org/reports/FBgn0036410 protein_coding_gene - - - "CG8100, lincRNA.S5087" "IPR005203:Hemocyanin, C-terminal, IPR005204:Hemocyanin, N-terminal, IPR013788:Hemocyanin/hexamerin, IPR014756:Immunoglobulin E-set, IPR008922:Uncharacterised domain, di-copper centre" CG8100 27-Aug-18 DroID_v2018_08 - - "Cele\C49A9.3, Cele\F58F9.4, Cele\C49A9.2" - - - viable FBgn0035641 CG5568 - http://flybase.org/reports/FBgn0035641 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR000873 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR000873 - CG5568 "IPR000873:AMP-dependent synthetase/ligase, IPR025110:AMP-binding enzyme C-terminal domain" CG5568 27-Aug-18 DroID_v2018_08 "Drer\acsf3, Drer\acsbg1" Scer\PCS60 "Cele\acs-6, Cele\acs-9, Cele\mec-18, Cele\C25G6.3, Cele\C32E8.6, Cele\acs-10, Cele\acs-7, Cele\acs-14" Xtro\acsf3 "Mmus\Acss2, Mmus\Acsbg1, Mmus\Acsf3" "Hsap\ACSBG1, Hsap\ACSS2, Hsap\ACSF3" lethal FBgn0260246 GSd210 - http://flybase.org/reports/FBgn0260246 gene - - - GSd210 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,neuroanatomy defective" "ventral nerve cord,longitudinal connective" FBgn0028132 l(3)S051022a lethal (3) S051022a http://flybase.org/reports/FBgn0028132 gene - - - "0510/22, l(3)S051022, l(3)S051022a" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0000396 cv-b crossveinless b http://flybase.org/reports/FBgn0000396 - gene - - - cv-b - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive" "anterior crossvein,posterior crossvein" FBgn0036848 CG10424 - http://flybase.org/reports/FBgn0036848 protein_coding_gene ADP-dependent NAD(P)H-hydrate dehydratase activity ; GO:0052855 | inferred from electronic annotation with InterPro:IPR000631 - - CG10424 "IPR000631:ATP-dependent (S)-NAD(P)H-hydrate dehydratase, IPR017953:Carbohydrate kinase, predicted, conserved site, IPR029056:Ribokinase-like" CG10424 27-Aug-18 DroID_v2018_08 Drer\carkd Scer\YKL151C Cele\R107.2 Xtro\carkd Mmus\Naxd Hsap\NAXD "viable,fertile" FBgn0259720 CG42374 - http://flybase.org/reports/FBgn0259720 protein_coding_gene - DNA repair ; GO:0006281 | inferred from electronic annotation with InterPro:IPR031821 SOSS complex ; GO:0070876 | inferred from electronic annotation with InterPro:IPR031821 "CG42374, Dromel_CG9666_FBtr0074991_uORF" IPR031821:SOSS complex subunit C CG42374 27-Aug-18 DroID_v2018_08 Drer\inip - - Xtro\inip Mmus\Inip Hsap\INIP FBgn0027500 spd-2 spindle defective 2 http://flybase.org/reports/FBgn0027500 FBgn0014928 protein_coding_gene adenosine-diphosphatase activity ; GO:0043262 | inferred from biological aspect of ancestor with PANTHER:PTN000989736 centrosome organization ; GO:0051297 | inferred from mutant phenotype sperm aster formation ; GO:0035044 | inferred from mutant phenotype astral microtubule organization ; GO:0030953 | inferred from mutant phenotype centriole ; GO:0005814 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay pericentriolar material ; GO:0000242 | inferred from direct assay "SPD2, BcDNA:LD24702, anon-73Ba, Spd-2, CG17286, spd-2, D-SPD2, DSPD-2, SPD-2, DSpd-2, D-Spd2, CG17286-PA, spd2, Dspd-2, DSpd2, Spd2, dSpd2, Cep192, Dspd2, CEP192" IPR013783:Immunoglobulin-like fold CG17286 27-Aug-18 DroID_v2018_08 "Drer\nudt9, Drer\si:rp71-15i12.1" - Cele\ndx-6 - "Mmus\Nudt9, Mmus\Cep192" "Hsap\CEP192, Hsap\NUDT9" "lethal,maternal effect,male sterile,viable,lethal - all die before end of embryonic stage,non-rescuable maternal effect,recessive,some die during embryonic stage,female sterile,uncoordinated" "centriole | ectopic,spermatocyte,onion stage spermatid,aster,spermatid,spermatozoon,asterst-j7),centrosomest-j7),primary spermatocyte" FBgn0001045 fs(3)HO127 female sterile (3) HO127 http://flybase.org/reports/FBgn0001045 - gene - - - "fs(3)127A, fs(3)HO127" - - 27-Aug-18 DroID_v2018_08 - - - - - - female sterile oocyte FBgn0031130 CG15452 - http://flybase.org/reports/FBgn0031130 protein_coding_gene - - - CG15452 - CG15452 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" FBgn0065304 l(2)SH1975 lethal (2) SH1975 http://flybase.org/reports/FBgn0065304 gene - - - "l(2)SH1975, l(2)SH2 1975" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0065094 snmRNA:419 small non-messenger RNA 419 http://flybase.org/reports/FBgn0065094 non_protein_coding_gene - - - "Dm-419, CR33917, snmRNA:419" - CR33917 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032450 CG5776 - http://flybase.org/reports/FBgn0032450 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959, InterPro:IPR003960" - - CG5776 "IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR003960:ATPase, AAA-type, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR029067:CDC48 domain 2-like" CG5776 27-Aug-18 DroID_v2018_08 "Drer\spata5l1, Drer\zgc:136908, Drer\vcp, Drer\spata5" "Scer\CDC48, Scer\AFG2" "Cele\cdc-48.2, Cele\cdc-48.1, Cele\cdc-48.3" "Xtro\mecp2, Xtro\vcp, Xtro\spata5" "Mmus\Spata5, Mmus\Vcp" "Hsap\SPATA5L1, Hsap\SPATA5, Hsap\ATAD2B, Hsap\VCP" "viable,visible" trichogen cell FBgn0035228 CG12091 - http://flybase.org/reports/FBgn0035228 protein_coding_gene phosphoprotein phosphatase activity ; GO:0004721 | inferred from sequence or structural similarity with SGD:S000001118 protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity with SGD:S000001118 protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence model protein dephosphorylation ; GO:0006470 | inferred by curator from GO:0004722 protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity with SGD:S000001118 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with SGD:S000001118 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000268440 CG12091 IPR001932:PPM-type phosphatase domain CG12091 27-Aug-18 DroID_v2018_08 "Drer\pptc7a, Drer\pptc7b" Scer\PTC7 Cele\W09D10.4 Xtro\pptc7 Mmus\Pptc7 Hsap\PPTC7 viable FBgn0028894 GMF Glia maturation factor http://flybase.org/reports/FBgn0028894 protein_coding_gene actin binding ; GO:0003779 | inferred from electronic annotation with InterPro:IPR002108 Arp2/3 complex binding ; GO:0071933 | inferred from electronic annotation with InterPro:IPR011171 actin binding ; GO:0003779 | inferred from sequence or structural similarity "negative regulation of Arp2/3 complex-mediated actin nucleation ; GO:0034316 | inferred from direct assay inferred from genetic interaction with Arpc5, flr actin filament debranching ; GO:0071846 | inferred from direct assay regulation of actin filament polymerization ; GO:0030833 | inferred from mutant phenotype regulation of cell projection organization ; GO:0031344 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype" perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay lamellipodium ; GO:0030027 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cell periphery ; GO:0071944 | inferred from direct assay "DS02740.9, BG:DS02740.9, BcDNA:SD03793, GMF, CG5869, dGMF, gmf" "IPR002108:Actin-depolymerising factor homology domain, IPR011171:Glia maturation factor, IPR029006:ADF-H/Gelsolin-like domain" CG5869 27-Aug-18 DroID_v2018_08 "Drer\gmfg, Drer\gmfb" Scer\AIM7 Cele\Y50D7A.10 "Xtro\gmfb, Xtro\gmfg" "Mmus\Gmfg, Mmus\Gmfb" "Hsap\GMFG, Hsap\GMFB" viable FBgn0005480 l(1)ts1137 lethal (1) ts1137 http://flybase.org/reports/FBgn0005480 - gene - - - l(1)ts1137 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,heat sensitive" FBgn0065428 l(2)SH1504 lethal (2) SH1504 http://flybase.org/reports/FBgn0065428 gene - - - "l(2)SH1504, l(2)SH2 1504" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0001743 l(1)HM13 lethal (1) HM13 http://flybase.org/reports/FBgn0001743 - gene - - - l(1)HM13 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,cold sensitive,female sterile" FBgn0005084 fs(2)OW808 female sterile (2) OW808 http://flybase.org/reports/FBgn0005084 - gene - - - fs(2)OW808 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0050071 CG30071 - http://flybase.org/reports/FBgn0050071 protein_coding_gene - - - CG30071 - - 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC22029 E 0.68798794 0.156759211 1.402462133 1.586225263 0.353631181 0.660610817 FBgn0011169 l(1)291-3 lethal (1) 291-3 http://flybase.org/reports/FBgn0011169 FBgn0010199 gene - - - "291-3, l(1)291-3" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0051546 CG31546 - http://flybase.org/reports/FBgn0051546 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR020904 - - "CG2907, anon-WO0140519.189, CG31546" "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain, IPR020904:Short-chain dehydrogenase/reductase, conserved site" CG31546 27-Aug-18 DroID_v2018_08 "Drer\dhrs1, Drer\zgc:113054, Drer\elovl8b, Drer\pecr, Drer\zgc:101858, Drer\elovl7a, Drer\hsd17b14, Drer\elovl2, Drer\decr1, Drer\elovl1b, Drer\hsdl2, Drer\hsd17b8, Drer\elovl5, Drer\decr2, Drer\cbr4, Drer\dhrs7, Drer\elovl1a, Drer\elovl7b, Drer\elovl8a, Drer\elovl4a, Drer\bdh2, Drer\elovl4b" "Scer\SPS19, Scer\IRC24, Scer\OAR1, Scer\YIR035C" "Cele\F26D2.15, Cele\F28H7.2, Cele\C06E4.3, Cele\Y47G6A.21, Cele\C33E10.10, Cele\ZK829.1, Cele\dhs-23, Cele\Y47G6A.22, Cele\F25D1.5, Cele\dhs-11, Cele\dhs-25, Cele\dhs-14" "Xtro\pecr, Xtro\decr1, Xtro\hsdl2, Xtro\elovl7, Xtro\cbr4, Xtro\MGC79752, Xtro\hsd17b14, Xtro\elovl5, Xtro\decr2, Xtro\dhrs7, Xtro\hsd17b8, Xtro\elovl1, Xtro\MGC147226, Xtro\elovl2, Xtro\dhrs4" "Mmus\Hsd17b14, Mmus\Elovl4, Mmus\Elovl7, Mmus\Hsdl2, Mmus\Dhrs2, Mmus\Decr2, Mmus\Cbr4, Mmus\Dhrs7, Mmus\Bdh2, Mmus\Elovl2, Mmus\Dhrs1, Mmus\Decr1, Mmus\Pecr, Mmus\Elovl5, Mmus\H2-Ke6, Mmus\Dhrs4" "Hsap\ELOVL7, Hsap\DHRS4, Hsap\HSDL2, Hsap\DHRS7, Hsap\DHRS4L2, Hsap\CBR4, Hsap\DHRS2, Hsap\ELOVL4, Hsap\ELOVL2, Hsap\HSD17B8, Hsap\DECR2, Hsap\BDH2, Hsap\HSD17B14, Hsap\DHRS1, Hsap\ELOVL5, Hsap\ELOVL1, Hsap\DECR1, Hsap\PECR" viable FBgn0001639 l(1)dn19 lethal (1) discs normal 19 http://flybase.org/reports/FBgn0001639 - gene - - - "l(1)d.norm.-19, l(1)dn19" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0263880 l(3)A38 - http://flybase.org/reports/FBgn0263880 gene - - - l(3)A38 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,decreased cell number,somatic clone" "embryonic/larval brain,somatic clone" FBgn0036191 Sugb Sugar baby http://flybase.org/reports/FBgn0036191 protein_coding_gene - determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype - "CG7334, Sugb, Sug, sug" "IPR024989:Major facilitator superfamily associated domain, IPR020846:Major facilitator superfamily domain" CG7334 27-Aug-18 DroID_v2018_08 "Drer\mfsd6a, Drer\mfsd6b, Drer\mfsd6l" "Scer\TCM62, Scer\SLA1, Scer\GDS1, Scer\SEC72, Scer\GDH2, Scer\GCR2, Scer\YHR140W" "Cele\F09F3.5, Cele\R13A5.9, Cele\skpo-1" "Xtro\mfsd6l, Xtro\mfsd6" "Mmus\Ptgs2, Mmus\Mfsd6l, Mmus\Mfsd6" "Hsap\SCN10A, Hsap\MFSD6, Hsap\PTGS2, Hsap\MFSD6L" "viable,fertile,long lived" FBgn0052199 CG32199 - http://flybase.org/reports/FBgn0052199 protein_coding_gene "procollagen-proline 4-dioxygenase activity ; GO:0004656 | inferred from electronic annotation with InterPro:IPR013547 L-ascorbic acid binding ; GO:0031418 | inferred from electronic annotation with InterPro:IPR006620 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen ; GO:0016702 | inferred from electronic annotation with InterPro:IPR013547 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR006620" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005123, InterPro:IPR006620, InterPro:IPR013547" endoplasmic reticulum ; GO:0005783 | inferred from electronic annotation with InterPro:IPR013547 "CG13382, CG32199" "IPR011990:Tetratricopeptide-like helical domain, IPR006620:Prolyl 4-hydroxylase, alpha subunit, IPR013547:Prolyl 4-hydroxylase alpha-subunit, N-terminal, IPR005123:Oxoglutarate/iron-dependent dioxygenase" CG32199 27-Aug-18 DroID_v2018_08 "Drer\p4ha1b, Drer\p4ha1a, Drer\p4htm, Drer\p4ha3, Drer\zgc:152670, Drer\zgc:158254, Drer\p4ha2" - "Cele\C14E2.4, Cele\phy-3, Cele\phy-4, Cele\phy-2, Cele\Y43F8B.19" "Xtro\p4ha2, Xtro\p4ha1, Xtro\p4ha3" "Mmus\P4ha2, Mmus\P4htm, Mmus\P4ha3, Mmus\P4ha1" "Hsap\P4HA1, Hsap\P4HA2, Hsap\P4HA3, Hsap\P4HTM" viable FBgn0265850 lncRNA:CR44639 - http://flybase.org/reports/FBgn0265850 non_protein_coding_gene - - - CR44639 - CR44639 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036665 CG13024 - http://flybase.org/reports/FBgn0036665 protein_coding_gene - - - "BcDNA:RH61817, CG13024" - CG13024 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0032437 CR17024 - http://flybase.org/reports/FBgn0032437 pseudogene_attribute - - - "CG17024, CR17024" - CR17024 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032377 CG14937 - http://flybase.org/reports/FBgn0032377 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model "CG14937, FBXO17" "IPR001810:F-box domain, IPR032675:Leucine-rich repeat domain, L domain-like" CG14937 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0015767 Mst302 Male-specific transcript 302 http://flybase.org/reports/FBgn0015767 - gene - - - Mst302 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0022255 l(2)k01103 lethal (2) k01103 http://flybase.org/reports/FBgn0022255 - gene - - - l(2)k01103 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0051409 CG31409 - http://flybase.org/reports/FBgn0051409 protein_coding_gene - - - CG31409 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035737 Cpr65Ec Cuticular protein 65Ec http://flybase.org/reports/FBgn0035737 protein_coding_gene structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr65Ec, CG8634, DmelCpr65Ec" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG8634 27-Aug-18 DroID_v2018_08 Drer\LOC100003040 - "Cele\sdz-30, Cele\math-34, Cele\F44F1.4" - "Mmus\H2-K1, Mmus\2410137M14Rik" - FBgn0014119 anon-96Fd anon-96Fd http://flybase.org/reports/FBgn0014119 - gene - - - anon-96Fd - - 27-Aug-18 DroID_v2018_08 - - - - - - " larval stage , adult stage " " eye-antennal disc

, adult head

" FBgn0264436 lncRNA:CR43854 - http://flybase.org/reports/FBgn0264436 non_protein_coding_gene - - - CR43854 - CR43854 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002160 l(2)Sp1 lethal (2) Sp1 http://flybase.org/reports/FBgn0002160 - gene - - - l(2)Sp1 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0265075 lncRNA:CR44186 - http://flybase.org/reports/FBgn0265075 non_protein_coding_gene - - - CR44186 - CR44186 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0010458 l(2)00231 lethal (2) 00231 http://flybase.org/reports/FBgn0010458 - gene - - - l(2)00231 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0266408 lncRNA:CR45048 - http://flybase.org/reports/FBgn0266408 non_protein_coding_gene - - - CR45048 - CR45048 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0058219 CG40219 - http://flybase.org/reports/FBgn0058219 protein_coding_gene - - - CG40219 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060710 l(3)S070209b lethal (3) S070209b http://flybase.org/reports/FBgn0060710 gene - - - "0702/09, l(3)S070209b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0028101 l(3)S072613a lethal (3) S072613a http://flybase.org/reports/FBgn0028101 gene - - - "l(3)S072613, 0726/13, l(3)S072613a" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0003330 Sce Sex combs extra http://flybase.org/reports/FBgn0003330 FBgn0020911 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence or structural similarity with HGNC:10061 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q24434 zinc ion binding ; GO:0008270 | inferred from sequence model chromatin silencing ; GO:0006342 | inferred from direct assay ovarian follicle cell stalk formation ; GO:0030713 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype germarium-derived female germ-line cyst encapsulation ; GO:0030708 | inferred from mutant phenotype histone H2A monoubiquitination ; GO:0035518 | inferred from mutant phenotype sex comb development ; GO:0045498 | inferred from direct assay multicellular organism development ; GO:0007275 | inferred from direct assay ventral cord development ; GO:0007419 | inferred from mutant phenotype "condensed chromosome, centromeric region ; GO:0000779 | NOT inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay PRC1 complex ; GO:0035102 | inferred from direct assay PRC1 complex ; GO:0035102 | traceable author statement PcG protein complex ; GO:0031519 | inferred from direct assay nuclear chromatin ; GO:0000790 | inferred from direct assay nuclear envelope ; GO:0005635 | inferred from direct assay nucleolus ; GO:0005730 | inferred from direct assay" "dRING1, dRing, RING1, dRING, DRING, Ring, Rnf2, Dring, Ding, CG5595, Sce, SCE, RING, Ring/Sce, dring, dRing1, Sce/dRing, sce, RING/Sce" "IPR001841:Zinc finger, RING-type, IPR017907:Zinc finger, RING-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR032443:RAWUL domain" CG5595 27-Aug-18 DroID_v2018_08 "Drer\rnf2, Drer\lnx2b, Drer\lnx1" - "Cele\B0432.13, Cele\spat-3" "Xtro\rnf2, Xtro\traip, Xtro\ring1" "Mmus\Pcgf3, Mmus\Brca1, Mmus\Traip, Mmus\Rnf2, Mmus\Ring1" "Hsap\RNF2, Hsap\RING1, Hsap\PCGF3, Hsap\BRCA1" "lethal - all die before end of pupal stage,some die during pupal stage,suppressor of variegation,dominant,lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,decreased cell number,somatic clone,mitotic cell cycle defective,tumorigenic,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,partially lethal - majority die" "adult thorax,Fell hairs,ectopic,abdominal 4 ventral denticle belt,denticle belt,embryonic abdominal segment,rescuable maternal effect,embryonic abdominal segment 8,embryonic head,stage 14 embryo,embryonic thoracic segment,larval abdominal segment 7,larval abdominal segment 1,germline clone,larval abdominal segment 2,larval abdominal segment 3,larval abdominal segment 4,larval abdominal segment 5,larval abdominal segment 6,larval prothoracic segment,larval mesothoracic segment,larval metathoracic segment,Keilin's organ,Kolbchen,egg chamber,somatic clone,germarium region 3,interfollicle cell,cell non-autonomous,neuroblast,embryonic/larval tracheal system,eye disc,mesothoracic ventral denticle belt,metathoracic ventral denticle belt,prothoracic ventral denticle belt,wing,mesothoracic tergum" FBgn0024968 FebpN ftz enhancer binding protein N http://flybase.org/reports/FBgn0024968 - gene DNA binding ; GO:0003677 | inferred from direct assay biological_process ; GO:0008150 | no biological data available nucleus ; GO:0005634 | inferred from direct assay FebpN - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0020871 anon-Q177 anon-Q177 http://flybase.org/reports/FBgn0020871 - gene - - - "2-Q177, anon-Q177" - - 27-Aug-18 DroID_v2018_08 - - - - - - "fertile,chemical sensitive,recessive" FBgn0035558 CG11357 - http://flybase.org/reports/FBgn0035558 protein_coding_gene "galactosyltransferase activity ; GO:0008378 | inferred from electronic annotation with InterPro:IPR002659 transferase activity, transferring glycosyl groups ; GO:0016757 | inferred from sequence or structural similarity with EMBL:Y15062" protein glycosylation ; GO:0006486 | inferred from electronic annotation with InterPro:IPR002659 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002659 "BcDNA:GM04393, CG11357, dbeta3GnT, GalT2" "IPR002659:Glycosyl transferase, family 31" CG11357 27-Aug-18 DroID_v2018_08 "Drer\zgc:194551, Drer\zgc:194330, Drer\b3gnt7, Drer\b3gnt9, Drer\si:dkey-160o24.3, Drer\b3gnt3, Drer\LOC100535930, Drer\si:ch211-126g16.11, Drer\b3gnt2b, Drer\b3gnt2a, Drer\b3galt1a, Drer\b3gnt2l, Drer\b3galt4, Drer\LOC565422, Drer\b3gnt7l, Drer\si:dkey-175m17.6, Drer\zgc:86586, Drer\b3gnt5a, Drer\b3galnt2, Drer\b3gnt5b, Drer\b3galt2, Drer\si:ch211-126g16.10, Drer\b3galt1b" - "Cele\C54C8.3, Cele\T15D6.5, Cele\bus-17, Cele\C47F8.5, Cele\F48F7.3, Cele\T09F5.1, Cele\B0024.15, Cele\bre-2, Cele\C47F8.3, Cele\F14B6.6, Cele\T09E11.10, Cele\B0024.3, Cele\E03H4.11, Cele\F14B6.4, Cele\bre-5, Cele\C47F8.6" "Xtro\LOC100485652, Xtro\b3gnt3, Xtro\b3gnt5, Xtro\b3gnt4, Xtro\b3gnt2, Xtro\LOC100489278, Xtro\LOC100489267, Xtro\b3galt4, Xtro\LOC100494668, Xtro\b3galt1, Xtro\b3galt2, Xtro\LOC100487553, Xtro\LOC101732799, Xtro\b3galnt2, Xtro\LOC100486246, Xtro\LOC100494986, Xtro\LOC100493833, Xtro\b3gnt6, Xtro\b3gnt3" "Mmus\B3gnt6, Mmus\B3galt1, Mmus\B3galnt1, Mmus\B3gnt8, Mmus\B3galt2, Mmus\B3galnt2, Mmus\B3gnt7, Mmus\B3galt5, Mmus\B3gnt2, Mmus\B3gnt3, Mmus\B3gnt5, Mmus\B3gnt9, Mmus\B3galt4, Mmus\B3gnt4" "Hsap\B3GNT5, Hsap\B3GALT5, Hsap\B3GNT2, Hsap\B3GNT4, Hsap\B3GNT9, Hsap\B3GALT1, Hsap\B3GALNT1, Hsap\B3GNT6, Hsap\B3GALT4, Hsap\B3GALT2, Hsap\B3GNT3, Hsap\B3GALNT2, Hsap\B3GNT8, Hsap\B3GNT7" "learning defective,viable,fertile" FBgn0013673 mt:ATPase8 mitochondrial ATPase subunit 8 http://flybase.org/reports/FBgn0013673 FBgn0002867 protein_coding_gene hydrogen ion transmembrane transporter activity ; GO:0015078 | inferred from electronic annotation with InterPro:IPR001421 ATP synthesis coupled proton transport ; GO:0015986 | inferred from electronic annotation with InterPro:IPR001421 "mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) ; GO:0000276 | inferred from electronic annotation with InterPro:IPR001421" "CG34072, ATPase8, URF6L, mt:ATPase8, ATP8, atp8, Atp8ase" "IPR001421:ATP synthase protein 8, metazoa" CG34072 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0013574 l(3)82Fb lethal (3) 82Fb http://flybase.org/reports/FBgn0013574 - gene - - - l(3)82Fb - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive,lethal" "adult abdomen,adult head" FBgn0002380 l(3)93Bb lethal (3) 93Bb http://flybase.org/reports/FBgn0002380 - gene - - - "er4, l(3)er4, l(3)93Bb" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" wing FBgn0025423 Dl::Nrg Dl::Nrg http://flybase.org/reports/FBgn0025423 - engineered_fusion_gene - - - Dl::Nrg - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing vein,wing vein L3,wing blade" FBgn0265818 lncRNA:CR44607 - http://flybase.org/reports/FBgn0265818 non_protein_coding_gene - - - "lincRNA.15, CR44607" - CR44607 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037781 Fancl Fancl http://flybase.org/reports/FBgn0037781 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:20748 DNA repair ; GO:0006281 | inferred from mutant phenotype protein monoubiquitination ; GO:0006513 | inferred from mutant phenotype Fanconi anaemia nuclear complex ; GO:0043240 | inferred from electronic annotation with InterPro:IPR026848 cellular_component ; GO:0005575 | no biological data available "FANCL, CG12812, Fancl, FAL" "IPR019162:Fanconi anemia complex, subunit FancL, WD-repeat containing domain, IPR026848:E3 ubiquitin-protein ligase FANCL, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR026850:FANCL C-terminal domain" CG12812 27-Aug-18 DroID_v2018_08 Drer\fancl - "Cele\C09E7.8, Cele\E03H4.2" Xtro\fancl Mmus\Fancl Hsap\FANCL "visible,chemical conditional,chemical sensitive,viable" "eye,chemical conditional" DRSC14550 I -1.698582147 0.119800945 0.642479834 0.614919858 -0.255532089 1.083039591 FBgn0002664 mat(2)ea-A maternal effect early arrest A http://flybase.org/reports/FBgn0002664 - gene - - - "mat(2)earlyPB28, mat(2)ea-A" - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage" FBgn0031319 CG4896 - http://flybase.org/reports/FBgn0031319 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001876 RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:9902 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity "regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from sequence or structural similarity with HGNC:9902" nucleoplasm ; GO:0005654 | inferred from sequence or structural similarity with HGNC:9902 "cg4896, CG4896" "IPR000467:G-patch domain, IPR000504:RNA recognition motif domain, IPR001876:Zinc finger, RanBP2-type" CG4896 27-Aug-18 DroID_v2018_08 "Drer\rbm10, Drer\rbm5, Drer\LOC567058, Drer\aggf1" - Cele\T08B2.5 "Xtro\aggf1, Xtro\rbm5" "Mmus\Rbm5, Mmus\Rbm6, Mmus\Rbm10, Mmus\Gpatch2" "Hsap\RBM5, Hsap\RBM10, Hsap\RBM6" "viable,fertile" FBgn0065688 l(2)SH0649 lethal (2) SH0649 http://flybase.org/reports/FBgn0065688 gene - - - l(2)SH0649 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0043853 scaRNA:MeU5-C46 small Cajal body-specific RNA : MeU5-C46 http://flybase.org/reports/FBgn0043853 snoRNA_gene - - Cajal body ; GO:0015030 | inferred from direct assay "U85 scaRNA, CG31504, CR32863, snoRNA:MeU5-C46, MeU5-C46(U85), snoRNA:U85, dU85, U85scaRNA, U85, scaRNA:MeU5-C46, chr3R:3298692..3298881" - CR32863 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265429 CG44341 - http://flybase.org/reports/FBgn0265429 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44341 - CG44341 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263891 l(3)F58 - http://flybase.org/reports/FBgn0263891 gene - - - l(3)F58 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,cell cycle defective,somatic clone" "embryonic/larval brain,somatic clone,embryonic/larval neuroblast" FBgn0028663 VhaM9.7-b Vacuolar H[+] ATPase M9.7 subunit b http://flybase.org/reports/FBgn0028663 protein_coding_gene "proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | contributes_to inferred by curator from GO:0033181 proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from biological aspect of ancestor with PANTHER:PTN000262636 proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | contributes_to inferred from sequence model with Pfam:PF05493 hydrogen ion transmembrane transporter activity ; GO:0015078 | inferred from sequence model with InterPro:IPR008389,InterPro:IPR017385" "ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from electronic annotation with InterPro:IPR008389, InterPro:IPR017385 ATP hydrolysis coupled proton transport ; GO:0015991 | inferred by curator from GO:0033181 ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from sequence model inferred from sequence model with Pfam:PF05493" "proton-transporting V-type ATPase, V0 domain ; GO:0033179 | inferred from electronic annotation with InterPro:IPR008389, InterPro:IPR017385 plasma membrane proton-transporting V-type ATPase complex ; GO:0033181 | inferred from mutant phenotype vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220 | inferred from sequence model vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220 | inferred from sequence or structural similarity" "CG7625, Vha M9.7-2, vhaM9.7-2, vhaM9.2-2, anon-WO0118547.551, VhaM9.7-b, VhaM9.7-2, vhaM9.7-b, ATP6V0M9.7-2" "IPR008389:ATPase, V0 complex, subunit e1/e2, IPR017385:ATPase, V0 complex, subunit e1/e2, metazoa" CG7625 27-Aug-18 DroID_v2018_08 "Drer\pars2, Drer\atp6v0e1, Drer\atpv0e2" Scer\VMA9 Cele\vha-17 "Xtro\atp6v0e1, Xtro\atp6v0e2" "Mmus\Atp6v0e, Mmus\Atp6v0e2, Mmus\Pars2" "Hsap\ATP6V0E2, Hsap\ATP6V0E1" "lethal - all die before end of embryonic stage,some die during embryonic stage,body color defective,partially lethal - majority die,some die during pupal stage" "Malpighian tubule,mesothoracic tergum" FBgn0053120 CG33120 - http://flybase.org/reports/FBgn0053120 protein_coding_gene long-chain-alcohol O-fatty-acyltransferase activity ; GO:0047196 | inferred from biological aspect of ancestor with PANTHER:PTN001270476 diacylglycerol O-acyltransferase activity ; GO:0004144 | inferred from biological aspect of ancestor with PANTHER:PTN001270476 triglyceride biosynthetic process ; GO:0019432 | inferred from biological aspect of ancestor with PANTHER:PTN001270476 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN001270476 "CG10599, CG33120" "IPR009721:O-acyltransferase WSD1, C-terminal" CG33120 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0042094 Adk3 Adenylate kinase 3 http://flybase.org/reports/FBgn0042094 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000850, InterPro:IPR006259 nucleoside triphosphate adenylate kinase activity ; GO:0046899 | inferred from sequence or structural similarity with UniProtKB:P54819 adenylate kinase activity ; GO:0004017 | inferred from direct assay" ADP biosynthetic process ; GO:0006172 | inferred from sequence or structural similarity with UniProtKB:Q9UIJ7 mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:Q9UIJ7 mitochondrion ; GO:0005739 | inferred from direct assay "DAK3, bs12h03.y1, AK3, CG6612, Adk3, Dak3" "IPR000850:Adenylate kinase/UMP-CMP kinase, IPR006259:Adenylate kinase subfamily, IPR007862:Adenylate kinase, active site lid domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR033690:Adenylate kinase, conserved site, IPR028586:Adenylate kinase 3/4, mitochondrial" CG6612 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-199m3.4, Drer\ak8, Drer\ak3, Drer\ak7a, Drer\ak7b, Drer\ak4, Drer\ak2" "Scer\ADK1, Scer\ADK2" Cele\ZK673.2 "Xtro\ak8, Xtro\ak3, Xtro\ak9, Xtro\ak4, Xtro\ak7, Xtro\ak2" "Mmus\Ak7, Mmus\Ak4, Mmus\Ak3, Mmus\Ak2, Mmus\Ak8" "Hsap\AK4, Hsap\AK3, Hsap\AK8, Hsap\AK7, Hsap\AK9, Hsap\AK2" "visible,partially lethal - majority die,some die during pupal stage" trichogen cell DRSC16075 K -0.061362466 -0.066519469 0.642398619 0.525573035 1.125668306 2.045279065 FBgn0036552 CG17028 - http://flybase.org/reports/FBgn0036552 protein_coding_gene inositol monophosphate 1-phosphatase activity ; GO:0008934 | inferred from biological aspect of ancestor with PANTHER:PTN000465134 inositol monophosphate 1-phosphatase activity ; GO:0008934 | non-traceable author statement inositol monophosphate 1-phosphatase activity ; GO:0008934 | inferred from sequence or structural similarity with HGNC:6050 "phosphatidylinositol phosphorylation ; GO:0046854 | inferred from electronic annotation with InterPro:IPR000760, InterPro:IPR020550, InterPro:IPR020552 inositol phosphate dephosphorylation ; GO:0046855 | inferred from biological aspect of ancestor with PANTHER:PTN000465134 inositol metabolic process ; GO:0006020 | inferred from biological aspect of ancestor with PANTHER:PTN000465134 signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000465134 dephosphorylation ; GO:0016311 | non-traceable author statement inositol phosphate dephosphorylation ; GO:0046855 | inferred from sequence or structural similarity with HGNC:6050" cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:6050 "IMP, CG17028" "IPR000760:Inositol monophosphatase-like, IPR033942:Inositol monophosphatase, IPR020550:Inositol monophosphatase, conserved site, IPR020552:Inositol monophosphatase, Lithium-sensitive, IPR020583:Inositol monophosphatase, metal-binding site" CG17028 27-Aug-18 DroID_v2018_08 "Drer\impa1, Drer\impa2" "Scer\INM1, Scer\INM2" Cele\ttx-7 "Xtro\impa1, Xtro\impa2" "Mmus\Impad1, Mmus\Impa1, Mmus\Impa2" "Hsap\IMPA2, Hsap\IMPAD1, Hsap\IMPA1" viable DRSC29850 K 0.345656475 0.83111402 0.29969736 -0.129991268 1.610369987 -0.166102827 FBgn0036224 Rpt4R Regulatory particle triple-A ATPase 4-related http://flybase.org/reports/FBgn0036224 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959, InterPro:IPR003960 TBP-class protein binding ; GO:0017025 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 ATPase activity ; GO:0016887 | inferred from sequence model proteasome-activating ATPase activity ; GO:0036402 | inferred from biological aspect of ancestor with PANTHER:PTN000553036" proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from sequence or structural similarity with Rpt4 ER-associated ubiquitin-dependent protein catabolic process ; GO:0030433 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ; GO:0045899 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 "proteasome regulatory particle, base subcomplex ; GO:0008540 | inferred from sequence or structural similarity with SGD:S000005785 nuclear proteasome complex ; GO:0031595 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 cytosolic proteasome complex ; GO:0031597 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 proteasome regulatory particle, base subcomplex ; GO:0008540 | inferred from biological aspect of ancestor with PANTHER:PTN000553036" "Dm_Rpt4c, DmCG7257, Rpt4R, 7257, CG7257" "IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR003960:ATPase, AAA-type, conserved site, IPR005937:26S proteasome subunit P45, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG7257 27-Aug-18 DroID_v2018_08 "Drer\psmc5, Drer\wdr12, Drer\psmc2, Drer\psmc6" Scer\RPT4 "Cele\rpt-4, Cele\F56F11.4, Cele\rpt-6" "Xtro\wdr12, Xtro\psmc2, Xtro\psmc5, Xtro\psmc6" "Mmus\Psmc5, Mmus\Psmc6, Mmus\Psmc2, Mmus\Wdr12" "Hsap\PSMC6, Hsap\PSMC2, Hsap\WDR12, Hsap\PSMC5" "partially lethal - majority die,some die during pupal stage" FBgn0263408 asRNA:CR43454 - http://flybase.org/reports/FBgn0263408 non_protein_coding_gene - - - CR43454 - CR43454 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0020293 l(1)EH275a lethal (1) EH275a http://flybase.org/reports/FBgn0020293 - gene - - - l(1)EH275a - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0038974 CG5377 - http://flybase.org/reports/FBgn0038974 protein_coding_gene - - - CG5377 "IPR029058:Alpha/Beta hydrolase fold, IPR000073:Alpha/beta hydrolase fold-1" CG5377 27-Aug-18 DroID_v2018_08 Drer\bphl "Scer\IMO32, Scer\LPX1" Cele\K01A2.5 Xtro\bphl Mmus\Bphl Hsap\BPHL viable FBgn0053516 dpr3 defective proboscis extension response 3 http://flybase.org/reports/FBgn0053516 protein_coding_gene molecular_function ; GO:0003674 | no biological data available store-operated calcium entry ; GO:0002115 | inferred from mutant phenotype sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with dpr1 synapse organization ; GO:0050808 | inferred from expression pattern integral component of plasma membrane ; GO:0005887 | inferred from sequence model "CG15381, CG15380, CG15379, Dpr-3, CT35425, CG33516, dpr3, CRACM2, Dpr3" "IPR013783:Immunoglobulin-like fold, IPR013106:Immunoglobulin V-set domain, IPR007110:Immunoglobulin-like domain, IPR003599:Immunoglobulin subtype, IPR003598:Immunoglobulin subtype 2" CG33516 27-Aug-18 DroID_v2018_08 "Drer\itgb4, Drer\lrit3b, Drer\lrit3a, Drer\kirrelb, Drer\ncam1b, Drer\LOC101885444, Drer\si:ch1073-459j12.1, Drer\kirrel3a, Drer\LOC101885725, Drer\lrit1a, Drer\kirrel3l, Drer\kirrel3b, Drer\ush2a, Drer\si:ch211-163c2.2, Drer\sdk1a, Drer\sdk1b, Drer\kirrela, Drer\dscama, Drer\LOC100333196, Drer\paplna, Drer\igsf9a, Drer\igsf9bb, Drer\lrit1b, Drer\si:ch211-264f5.6, Drer\si:dkey-65b12.12" - Cele\zig-8 "Xtro\kirrel2, Xtro\nfasc, Xtro\papln, Xtro\obsl1, Xtro\lrit3, Xtro\igsf9b" "Mmus\Sdk1, Mmus\Kirrel3, Mmus\Lrit1, Mmus\Lrit3, Mmus\Ptprq, Mmus\Igsf9b, Mmus\Kirrel, Mmus\Kirrel2, Mmus\Papln" "Hsap\KIRREL2, Hsap\IGSF9B, Hsap\KIRREL3, Hsap\LRIT3, Hsap\USH2A, Hsap\LRIT1, Hsap\PAPLN, Hsap\SDK1, Hsap\KIRREL" viable FBgn0037815 Rrp46 Rrp46 http://flybase.org/reports/FBgn0037815 protein_coding_gene - "polyadenylation-dependent snoRNA 3'-end processing ; GO:0071051 | inferred from biological aspect of ancestor with PANTHER:PTN000237329 regulation of gene expression ; GO:0010468 | inferred from mutant phenotype rRNA 3'-end processing ; GO:0031125 | inferred from biological aspect of ancestor with PANTHER:PTN000237329 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' ; GO:0034427 | inferred from biological aspect of ancestor with PANTHER:PTN000237329 nuclear mRNA surveillance ; GO:0071028 | inferred from biological aspect of ancestor with PANTHER:PTN000237329 U4 snRNA 3'-end processing ; GO:0034475 | inferred from biological aspect of ancestor with PANTHER:PTN000237329 rRNA catabolic process ; GO:0016075 | inferred from biological aspect of ancestor with PANTHER:PTN000237327" cytoplasm ; GO:0005737 | inferred from direct assay nuclear exosome (RNase complex) ; GO:0000176 | inferred from sequence or structural similarity with SGD:S000003327 inferred from direct assay cytoplasmic exosome (RNase complex) ; GO:0000177 | inferred from biological aspect of ancestor with PANTHER:PTN000237328 exosome (RNase complex) ; GO:0000178 | inferred from direct assay nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000237329 "CG4043, dRrp46, Rrp46, rrp46" "IPR015847:Exoribonuclease, phosphorolytic domain 2, IPR001247:Exoribonuclease, phosphorolytic domain 1, IPR027408:PNPase/RNase PH domain, IPR020568:Ribosomal protein S5 domain 2-type fold" CG4043 27-Aug-18 DroID_v2018_08 Drer\exosc5 Scer\RRP46 Cele\crn-5 Xtro\exosc5 Mmus\Exosc5 Hsap\EXOSC5 "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0015441 l(1)6DEa lethal (1) 6DEa http://flybase.org/reports/FBgn0015441 - gene - - - l(1)6DEa - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0037099 CG7173 - http://flybase.org/reports/FBgn0037099 protein_coding_gene - - - CG7173 "IPR002350:Kazal domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG7173 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0000778 fs(1)A1371 female sterile (1) A1371 http://flybase.org/reports/FBgn0000778 - gene - - - "fs(1)1371, fs(1)A1371" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,maternal effect,female sterile,recessive,heat sensitive,non-rescuable maternal effect" "blastoderm embryo,gastrula embryo" FBgn0015932 dsRNABP6 ds-RNA binding protein 6 http://flybase.org/reports/FBgn0015932 - gene - - - "dsRNABP#6, dsRNABP6" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259335 EP-M89 - http://flybase.org/reports/FBgn0259335 gene - - - EP-M89 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing vein,wing margin,wing,chaeta" FBgn0060338 l(3)S144507a lethal (3) S144507a http://flybase.org/reports/FBgn0060338 gene - - - "1445/07, l(3)S144507a" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0262126 Sec24CD Secretory 24CD http://flybase.org/reports/FBgn0262126 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR006895 "positive regulation of extracellular matrix constituent secretion ; GO:0003331 | inferred from mutant phenotype cell morphogenesis ; GO:0000902 | inferred from mutant phenotype lumen formation, open tracheal system ; GO:0035149 | inferred from mutant phenotype positive regulation of cell-cell adhesion ; GO:0022409 | inferred from mutant phenotype endoplasmic reticulum organization ; GO:0007029 | inferred from mutant phenotype protein secretion ; GO:0009306 | inferred from mutant phenotype chitin-based cuticle development ; GO:0040003 | inferred from mutant phenotype cargo loading into COPII-coated vesicle ; GO:0090110 | inferred from sequence or structural similarity with SGD:S000001371 regulation of cell shape ; GO:0008360 | inferred from mutant phenotype protein localization to cell surface ; GO:0034394 | inferred from mutant phenotype Golgi organization ; GO:0007030 | inferred from mutant phenotype muscle attachment ; GO:0016203 | inferred from mutant phenotype regulation of tube size, open tracheal system ; GO:0035151 | inferred from mutant phenotype protein targeting to plasma membrane ; GO:0072661 | inferred from mutant phenotype basement membrane organization ; GO:0071711 | inferred from mutant phenotype maintenance of cell polarity ; GO:0030011 | inferred from mutant phenotype regulation of tube diameter, open tracheal system ; GO:0035158 | inferred from mutant phenotype positive regulation of cuticle pigmentation ; GO:0048081 | inferred from mutant phenotype" COPII vesicle coat ; GO:0030127 | inferred from sequence or structural similarity with SGD:S000001371 endoplasmic reticulum exit site ; GO:0070971 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay "CG10882, Sec24, Sec24CD, sten, BcDNA:LP05220, FBgn0031408, gho, sfb3, sec24, Sten" "IPR002035:von Willebrand factor, type A, IPR029006:ADF-H/Gelsolin-like domain, IPR006895:Zinc finger, Sec23/Sec24-type, IPR006896:Sec23/Sec24, trunk domain, IPR006900:Sec23/Sec24, helical domain, IPR007123:Gelsolin-like domain, IPR012990:Sec23/Sec24 beta-sandwich" CG10882 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-13n15.2, Drer\sec24c, Drer\sec24d" "Scer\SFB2, Scer\SFB3, Scer\SEC24" Cele\sec-24.1 Xtro\sec24d "Mmus\Sec24d, Mmus\Sec24c" "Hsap\SEC24C, Hsap\SEC24D" FBgn0061500 l(2)44Fp lethal (2) 44Fp http://flybase.org/reports/FBgn0061500 gene - - - "l(2)44Fk, l(2)44Fp" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0267887 CR46175 - http://flybase.org/reports/FBgn0267887 pseudogene_attribute - - - "CR46175, CG12717-related" - CR46175 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262387 mir-190 mir-190 stem loop http://flybase.org/reports/FBgn0262387 miRNA_gene - muscle cell cellular homeostasis ; GO:0046716 | inferred from mutant phenotype - "dme-mir-190, mir-190, miR-190, MIR-190, CR42915, dme-miR-190" - CR42915 27-Aug-18 DroID_v2018_08 - - - - - - "visible,lethal,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of pupal stage,some die during pupal stage,partially lethal - majority die" "eye,wing,wing margin,wing vein,1st posterior cell" FBgn0267760 asRNA:CR46091 - http://flybase.org/reports/FBgn0267760 non_protein_coding_gene - - - CR46091 - CR46091 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0082622 S(CycE[JP])42S33 S(CycE[JP])42S33 http://flybase.org/reports/FBgn0082622 gene - - - "42S33, S(CycE[JP])42S33" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0031820 Daxx Daxx-like protein http://flybase.org/reports/FBgn0031820 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with p53 "response to oxidative stress ; GO:0006979 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from mutant phenotype regulation of apoptotic process ; GO:0042981 | inferred from genetic interaction with p53" - "CG9537, Daxx, DLP" IPR005012:Daxx protein CG9537 27-Aug-18 DroID_v2018_08 Drer\daxx - - Xtro\daxx Mmus\Daxx Hsap\DAXX "viable,short lived,female fertile,reduced,oxidative stress response defective,lethal,visible,increased cell death" "wing,wing disc" FBgn0263389 CG43441 - http://flybase.org/reports/FBgn0263389 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43441 - CG43441 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0083973 dunk disrupted underground network http://flybase.org/reports/FBgn0083973 protein_coding_gene - - - "CG34137, dunk" - CG34137 27-Aug-18 DroID_v2018_08 - - - - - - DRSC36514 K 2.001942348 1.745744674 FBgn0260256 GSd316 - http://flybase.org/reports/FBgn0260256 gene - - - GSd316 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0040978 CG7473 - http://flybase.org/reports/FBgn0040978 protein_coding_gene - - - CG7473 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262782 Mdh1 Malate dehydrogenase 1 http://flybase.org/reports/FBgn0262782 protein_coding_gene L-malate dehydrogenase activity ; GO:0030060 | inferred from direct assay carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR015955 NADH metabolic process ; GO:0006734 | inferred from biological aspect of ancestor with PANTHER:PTN000600336 oxaloacetate metabolic process ; GO:0006107 | inferred from biological aspect of ancestor with PANTHER:PTN000600336 malate metabolic process ; GO:0006108 | inferred from biological aspect of ancestor with PANTHER:PTN000600336 tricarboxylic acid cycle ; GO:0006099 | inferred from biological aspect of ancestor with PANTHER:PTN000600336 lateral inhibition ; GO:0046331 | inferred from mutant phenotype lipid particle ; GO:0005811 | inferred from direct assay cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN001157397 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN001157397 peroxisome ; GO:0005777 | inferred from sequence model "CG5362, Mdh-1, MDH, Mdh, Mdh2, cMdh, MDH-1, sMdh, MdhD, Mdh1, CT17038" "IPR001236:Lactate/malate dehydrogenase, N-terminal, IPR001252:Malate dehydrogenase, active site, IPR001557:L-lactate/malate dehydrogenase, IPR010945:Malate dehydrogenase, type 2, IPR011274:Malate dehydrogenase, NAD-dependent, cytosolic, IPR015955:Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal, IPR016040:NAD(P)-binding domain, IPR022383:Lactate/malate dehydrogenase, C-terminal" CG5362 27-Aug-18 DroID_v2018_08 "Drer\mdh1aa, Drer\mdh1b, Drer\mdh1ab" "Scer\MDH1, Scer\MDH3" Cele\mdh-1 Xtro\mdh1 "Mmus\Mdh1, Mmus\Mdh1b" "Hsap\MDH1B, Hsap\MDH1" FBgn0039099 GILT2 Gamma-interferon-inducible lysosomal thiol reductase 2 http://flybase.org/reports/FBgn0039099 protein_coding_gene "oxidoreductase activity, acting on a sulfur group of donors ; GO:0016667 | inferred from sequence or structural similarity with HGNC:5398 disulfide oxidoreductase activity ; GO:0015036 | inferred from sequence model with Pfam:PF03227" oxidation-reduction process ; GO:0055114 | inferred from sequence or structural similarity with HGNC:5398 oxidation-reduction process ; GO:0055114 | inferred from sequence model with Pfam:PF03227 positive regulation of defense response to bacterium ; GO:1900426 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "anon-EST:Posey120, CG10157, GILT, GILT2" "IPR004911:Gamma interferon inducible lysosomal thiol reductase GILT, IPR012336:Thioredoxin-like fold" CG10157 27-Aug-18 DroID_v2018_08 "Drer\ifi30, Drer\si:dkey-197i20.6" - "Cele\pqn-48, Cele\Y18D10A.2, Cele\R07E5.4, Cele\ZK669.2, Cele\C02D5.2, Cele\ZK669.3, Cele\F37H8.5, Cele\W04A4.3" Xtro\ifi30 Mmus\Ifi30 Hsap\IFI30 "immune response defective,long lived,viable" FBgn0013987 MAPk-Ak2 MAP kinase activated protein-kinase-2 http://flybase.org/reports/FBgn0013987 FBgn0029802 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 calmodulin-dependent protein kinase activity ; GO:0004683 | inferred from biological aspect of ancestor with PANTHER:PTN000681419 protein kinase activity ; GO:0004672 | inferred from sequence or structural similarity protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement calmodulin binding ; GO:0005516 | inferred from biological aspect of ancestor with PANTHER:PTN000681419 signal transducer activity ; GO:0004871 | inferred from biological aspect of ancestor with PANTHER:PTN001553005 calcium-dependent protein serine/threonine kinase activity ; GO:0009931 | inferred from biological aspect of ancestor with PANTHER:PTN000681419" protein autophosphorylation ; GO:0046777 | inferred from biological aspect of ancestor with PANTHER:PTN000681419 protein phosphorylation ; GO:0006468 | non-traceable author statement positive regulation of cell size ; GO:0045793 | inferred from genetic interaction with gig protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with HGNC:6887 peptidyl-serine phosphorylation ; GO:0018105 | inferred from biological aspect of ancestor with PANTHER:PTN000681419 regulation of JNK cascade ; GO:0046328 | inferred from genetic interaction with bsk inferred from genetic interaction with Mkk4 inferred from genetic interaction with Tak1 regulation of cell shape ; GO:0008360 | inferred from mutant phenotype response to salt stress ; GO:0009651 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001553005 cell adhesion ; GO:0007155 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000681419 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:6887 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000681419 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:6887 "MAPKAP, CG3086, DmMAPKAPK-2, MAPk-Ak2, MK2, MAPKAPK-2, dMK2" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR027442:MAP kinase activated protein kinase, C-terminal domain" CG3086 27-Aug-18 DroID_v2018_08 "Drer\mapkapk3, Drer\mapkapk2a, Drer\mapkapk2b, Drer\mapkapk5" "Scer\RCK1, Scer\RCK2" "Cele\mak-2, Cele\mak-1" "Xtro\mapkapk3, Xtro\mapkapk5, Xtro\mapkapk2" "Mmus\Mapkapk5, Mmus\Mapkapk2, Mmus\Mapkapk3" "Hsap\MAPKAPK2, Hsap\MAPKAPK5, Hsap\MAPKAPK3" " embryonic stage -- adult stage , oogenesis stage && adult stage | female , embryonic stage | early " ovary

"viable,partially lethal - majority live,nutrition conditional,melanotic mass phenotype" "embryonic/larval hindgut,posterior,nutrition conditional" FBgn0002045 l(2)37Di lethal (2) 37Di http://flybase.org/reports/FBgn0002045 - gene - - - "E103, l(2)E103, l(2)37Di" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0051021 CG31021 - http://flybase.org/reports/FBgn0051021 protein_coding_gene "oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen ; GO:0016702 | inferred from electronic annotation with InterPro:IPR013547 procollagen-proline 4-dioxygenase activity ; GO:0004656 | inferred from electronic annotation with InterPro:IPR013547" oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR013547 endoplasmic reticulum ; GO:0005783 | inferred from electronic annotation with InterPro:IPR013547 "CG9708, CG31021" "IPR013547:Prolyl 4-hydroxylase alpha-subunit, N-terminal, IPR011990:Tetratricopeptide-like helical domain" CG31021 27-Aug-18 DroID_v2018_08 "Drer\p4ha1b, Drer\zgc:158254, Drer\p4ha1a, Drer\p4htm, Drer\p4ha3, Drer\zgc:152670" - "Cele\phy-4, Cele\phy-2, Cele\dpy-18, Cele\C14E2.4, Cele\Y43F8B.19, Cele\phy-3" "Xtro\p4ha2, Xtro\p4ha3, Xtro\p4ha1" "Mmus\P4ha3, Mmus\P4ha2, Mmus\P4htm, Mmus\P4ha1" "Hsap\P4HA2, Hsap\P4HA3, Hsap\P4HTM, Hsap\P4HA1" viable FBgn0029154 Menl-1 Malic enzyme like-1 http://flybase.org/reports/FBgn0029154 protein_coding_gene "NAD binding ; GO:0051287 | inferred from electronic annotation with InterPro:IPR012302 malate dehydrogenase (decarboxylating) (NAD+) activity ; GO:0004471 | inferred from electronic annotation with InterPro:IPR001891, InterPro:IPR012301, InterPro:IPR012302, InterPro:IPR015884 malate dehydrogenase (decarboxylating) (NADP+) activity ; GO:0004473 | inferred from biological aspect of ancestor with PANTHER:PTN000601052" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001891, InterPro:IPR012301, InterPro:IPR012302, InterPro:IPR015884 pyruvate metabolic process ; GO:0006090 | inferred from biological aspect of ancestor with PANTHER:PTN000601050 malate metabolic process ; GO:0006108 | inferred from biological aspect of ancestor with PANTHER:PTN000601050" mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN001157886 "CG30097, CG7964, Menl-1" "IPR001891:Malic oxidoreductase, IPR012301:Malic enzyme, N-terminal domain, IPR012302:Malic enzyme, NAD-binding, IPR015884:Malic enzyme, conserved site, IPR016040:NAD(P)-binding domain" CG7964 27-Aug-18 DroID_v2018_08 "Drer\me1, Drer\me3, Drer\me2, Drer\LOC101882012" Scer\MAE1 Cele\men-1 "Xtro\me3, Xtro\me2" "Mmus\Me3, Mmus\Me2, Mmus\Me1" "Hsap\ME1, Hsap\ME3, Hsap\ME2" DRSC07470 I 1.812401681 0.496558877 0.116615905 -0.227669372 0.531992361 -1.302536282 FBgn0010831 l(3)04063 lethal (3) 04063 http://flybase.org/reports/FBgn0010831 - gene - - - l(3)04063 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0020842 l(2)BV "Blacksburg, VA" http://flybase.org/reports/FBgn0020842 - gene - - - l(2)BV - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0032585 CG4580 - http://flybase.org/reports/FBgn0032585 protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR018497" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR008753, InterPro:IPR018497" - CG4580 "IPR000718:Peptidase M13, IPR018497:Peptidase M13, C-terminal domain, IPR008753:Peptidase M13, N-terminal domain" CG4580 27-Aug-18 DroID_v2018_08 "Drer\ece2b, Drer\phex, Drer\mmel1, Drer\ece1" - "Cele\nep-13, Cele\nep-3, Cele\nep-8, Cele\nep-23, Cele\nep-9, Cele\nep-19, Cele\nep-24, Cele\nep-21, Cele\nep-26, Cele\nep-5, Cele\nep-20, Cele\nep-10, Cele\nep-7, Cele\nep-6, Cele\nep-18, Cele\nep-12" "Xtro\ecel1, Xtro\ece1, Xtro\ece2, Xtro\mmel1" "Mmus\Ecel1, Mmus\Ece2, Mmus\Ece1, Mmus\Mme, Mmus\Phex, Mmus\Kel, Mmus\Mmel1" "Hsap\KEL, Hsap\ECE1, Hsap\MME, Hsap\ECE2, Hsap\PHEX, Hsap\ECEL1, Hsap\MMEL1" viable FBgn0029649 CG4116 - http://flybase.org/reports/FBgn0029649 protein_coding_gene - - - CG4116 - CG4116 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible" trichogen cell FBgn0025483 l(3)Ax27 lethal (3) Ax27 http://flybase.org/reports/FBgn0025483 - gene - - - "Ax27, l(3)Ax27" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0030684 CG8260 - http://flybase.org/reports/FBgn0030684 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG8260 "IPR011333:SKP1/BTB/POZ domain, IPR000210:BTB/POZ domain, IPR011705:BTB/Kelch-associated, IPR031750:Domain of unknown function DUF4734" CG8260 27-Aug-18 DroID_v2018_08 Drer\klhl41a - Cele\kel-3 - - - "viable,visible" trichogen cell FBgn0000820 fs(1)K1193 female sterile (1) K1193 http://flybase.org/reports/FBgn0000820 - gene - - - fs(1)K1193 - - 27-Aug-18 DroID_v2018_08 - - - - - - female sterile FBgn0023177 Pp4-19C Protein phosphatase 19C http://flybase.org/reports/FBgn0023177 "FBgn0005784, FBgn0031112, FBgn0031113, FBgn0042229, FBgn0052505" protein_coding_gene "hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR004843, InterPro:IPR006186 protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity protein serine/threonine phosphatase activity ; GO:0004722 | non-traceable author statement" microtubule-based process ; GO:0007017 | inferred from mutant phenotype protein dephosphorylation ; GO:0006470 | inferred from sequence or structural similarity mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype regulation of mitotic cell cycle ; GO:0007346 | inferred from mutant phenotype protein dephosphorylation ; GO:0006470 | non-traceable author statement "centrosome ; GO:0005813 | inferred from direct assay chromosome, centromeric region ; GO:0000775 | inferred from physical interaction with Cenp-C protein phosphatase 4 complex ; GO:0030289 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay" "PPP4c, DmPpp4-19C, PP4, CG1459, pp4, PP4 19C, PPX, PpX, CG18339, CG1596, CG32505, Pp4-19C, PP1, PP4C, dPP4, PP4-19C, Ppp4c, PP4c, PP4-19c" "IPR004843:Calcineurin-like phosphoesterase domain, ApaH type, IPR006186:Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase, IPR029052:Metallo-dependent phosphatase-like" CG32505 27-Aug-18 DroID_v2018_08 "Drer\ppp2ca, Drer\ppp4ca, Drer\zgc:56064, Drer\ppp6c, Drer\ppp2cb, Drer\ppp4cb" "Scer\PPH3, Scer\PPH22, Scer\SIT4, Scer\PPG1, Scer\YNL217W, Scer\PPH21" "Cele\pph-4.2, Cele\pph-4.1, Cele\pph-6" "Xtro\ppp6c, Xtro\ppp2cb, Xtro\ppp4c, Xtro\ppp2ca" "Mmus\Ppp2cb, Mmus\Ppp2ca, Mmus\Ppp4c, Mmus\Ppp6c" "Hsap\PPP6C, Hsap\PPP2CB, Hsap\PPP2CA, Hsap\PPP4C" "partially lethal - majority die,maternal effect,recessive,some die during embryonic stage,lethal,neuroanatomy defective,visible,some die during pupal stage,female semi-sterile,female fertile" "centrosome | embryonic stage | maternal effect,microtubule | embryonic stage | maternal effect,mitotic domain,maternal effect,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum,synapse,neuromuscular junction" DRSC21251 I -1.040187241 -3.547631511 -1.103693159 -1.353044199 0.049852253 -0.769667735 FBgn0033128 Tsp42Eg Tetraspanin 42Eg http://flybase.org/reports/FBgn0033128 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from sequence model "CG12142, Dm.Tsp42Eg, BcDNA:GM06962, Tsp42Eg" "IPR018499:Tetraspanin/Peripherin, IPR000301:Tetraspanin, IPR008952:Tetraspanin, EC2 domain" CG12142 27-Aug-18 DroID_v2018_08 "Drer\tspan9b, Drer\tspan9a, Drer\tspan35, Drer\tspan34, Drer\cd63, Drer\tspan4a, Drer\zgc:64051, Drer\tspan4b, Drer\upk1a, Drer\tspan18b, Drer\tspan37, Drer\tspan18a" - "Cele\tsp-6, Cele\tsp-19, Cele\tsp-7, Cele\tsp-5, Cele\tsp-11, Cele\tsp-4, Cele\tsp-8, Cele\tsp-13, Cele\tsp-10" - "Mmus\Upk1a, Mmus\Upk1b, Mmus\Tspan18, Mmus\Tspan1, Mmus\Tspan8, Mmus\Cd63, Mmus\Tspan9, Mmus\Tspan4, Mmus\Cd53" "Hsap\TSPAN16, Hsap\TSPAN9, Hsap\CD53, Hsap\UPK1A, Hsap\TSPAN18, Hsap\TSPAN8, Hsap\TSPAN1, Hsap\TSPAN4, Hsap\UPK1B" "partially lethal - majority die,some die during pupal stage" FBgn0037368 CG1239 - http://flybase.org/reports/FBgn0037368 protein_coding_gene "methyltransferase activity ; GO:0008168 | inferred from electronic annotation with InterPro:IPR010675, InterPro:IPR024160" neurogenesis ; GO:0022008 | inferred from mutant phenotype - "cg1239, CG1239" "IPR010675:RNA methyltransferase bin3, C-terminal, IPR024160:Bin3-type S-adenosyl-L-methionine binding domain, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG1239 27-Aug-18 DroID_v2018_08 "Drer\si, Drer\mepce, Drer\si:ch1073-157b13.1" - Cele\Y17G7B.18 - "Mmus\Bcdin3d, Mmus\Mepce" "Hsap\BCDIN3D, Hsap\MEPCE" "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "ganglion mother cell,mesothoracic tergum" FBgn0065368 l(2)SH1709 lethal (2) SH1709 http://flybase.org/reports/FBgn0065368 gene - - - "l(2)SH1709, l(2)SH2 1709" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0265315 lncRNA:CR44288 - http://flybase.org/reports/FBgn0265315 non_protein_coding_gene - - - CR44288 - CR44288 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030915 CG6179 - http://flybase.org/reports/FBgn0030915 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:17946 ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN000316766 "negative regulation of catalytic activity ; GO:0043086 | inferred from sequence or structural similarity with UniProtKB:Q9Y314 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071013 protein ubiquitination ; GO:0016567 | inferred from biological aspect of ancestor with PANTHER:PTN000316766 negative regulation of nitric-oxide synthase activity ; GO:0051001 | inferred from sequence or structural similarity with UniProtKB:Q9Y314" nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q9Y314 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:Q9Y314 catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "CG6179, NOSIPL" "IPR016818:Nitric oxide synthase-interacting, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR031790:Nitric oxide synthase-interacting protein, zinc-finger" CG6179 27-Aug-18 DroID_v2018_08 Drer\nosip - Cele\R05G6.4 Xtro\nosip Mmus\Nosip Hsap\NOSIP "viable,fertile" FBgn0002271 l(3)69Bc lethal (3) 69Bc http://flybase.org/reports/FBgn0002271 - gene - - - "rsg33, l(3)rsg33, l(3)69Bc" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0052076 Alg10 Alpha 3 glucosyltransferase http://flybase.org/reports/FBgn0052076 protein_coding_gene dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity ; GO:0004583 | inferred from electronic annotation with InterPro:IPR016900 dolichol-linked oligosaccharide biosynthetic process ; GO:0006488 | inferred from electronic annotation with InterPro:IPR016900 endoplasmic reticulum membrane ; GO:0005789 | inferred from electronic annotation with InterPro:IPR016900 "Alg10, CG32076, CG7624, alg10, dAlg10" IPR016900:Alpha-2-glucosyltransferase Alg10 CG32076 27-Aug-18 DroID_v2018_08 Drer\alg10 Scer\DIE2 Cele\tag-179 Xtro\alg10 Mmus\Alg10b "Hsap\ALG10, Hsap\ALG10B" FBgn0039237 CG13640 - http://flybase.org/reports/FBgn0039237 protein_coding_gene - - - "BcDNA:RE70528, CG13640" - CG13640 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" FBgn0030673 CG15601 - http://flybase.org/reports/FBgn0030673 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15601 IPR006578:MADF domain CG15601 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC19670 K -0.05866301 0.335403336 -0.049939983 0.56349732 -0.115180018 1.602430298 FBgn0015682 elav::Dvir\elav elav::Dvir\elav http://flybase.org/reports/FBgn0015682 - engineered_fusion_gene - - - elav::Dvir\elav - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,sterile" FBgn0026666 MagR Magnetic receptor http://flybase.org/reports/FBgn0026666 "FBgn0030677, FBgn0063708" protein_coding_gene iron-sulfur cluster binding ; GO:0051536 | inferred from electronic annotation with InterPro:IPR016092 structural molecule activity ; GO:0005198 | inferred from electronic annotation with InterPro:IPR016092 protein maturation by iron-sulfur cluster transfer ; GO:0097428 | inferred from electronic annotation with InterPro:IPR016092 response to magnetism ; GO:0071000 | inferred from direct assay - "CG8198, BcDNA:AT26381, l(1)G0136, MagR, dMagR" "IPR000361:FeS cluster biogenesis, IPR016092:FeS cluster insertion protein, IPR017870:FeS cluster insertion, C-terminal, conserved site" CG8198 27-Aug-18 DroID_v2018_08 Drer\isca1 Scer\ISA1 Cele\Y39B6A.3 Xtro\isca1 Mmus\Isca1 Hsap\ISCA1 "lethal,recessive,locomotor rhythm defective" DRSC20092 IK -0.358861444 -1.540499237 -0.490274825 0.13959556 2.862034549 -0.133821632 FBgn0050440 CG30440 - http://flybase.org/reports/FBgn0050440 protein_coding_gene Rho guanyl-nucleotide exchange factor activity ; GO:0005089 | inferred from sequence or structural similarity with trio positive regulation of Rho protein signal transduction ; GO:0035025 | inferred from sequence or structural similarity with trio cellular_component ; GO:0005575 | no biological data available "CG10412, CG12183, CG10416, CG30440" "IPR000219:Dbl homology (DH) domain, IPR001331:Guanine-nucleotide dissociation stimulator, CDC24, conserved site, IPR001849:Pleckstrin homology domain, IPR011993:PH domain-like" CG30440 27-Aug-18 DroID_v2018_08 "Drer\arhgef25b, Drer\plekhg4, Drer\LOC559907, Drer\LOC569231, Drer\zgc:158766, Drer\mcf2a, Drer\quo, Drer\mcf2la, Drer\mcf2l2, Drer\arhgef40, Drer\si:dkey-65j6.2, Drer\kalrnb" Scer\CDC24 "Cele\cgef-1, Cele\unc-73" "Xtro\arhgef40, Xtro\kalrn, Xtro\mcf2, Xtro\mcf2l" "Mmus\Arhgef40, Mmus\Mcf2l, Mmus\Mcf2, Mmus\Plekhg4, Mmus\D630003M21Rik" "Hsap\PLEKHG4B, Hsap\MCF2, Hsap\MCF2L2, Hsap\PLEKHG4, Hsap\MCF2L, Hsap\ARHGEF40, Hsap\KALRN" viable FBgn0024675 l(2)k00313 lethal (2) k00313 http://flybase.org/reports/FBgn0024675 - gene - - - "3/13, l(2)k00313" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0039448 TwdlQ TweedleQ http://flybase.org/reports/FBgn0039448 protein_coding_gene structural constituent of chitin-based cuticle ; GO:0005214 | inferred from sequence or structural similarity with TwdlD chitin-based cuticle development ; GO:0040003 | inferred from sequence or structural similarity with TwdlD body morphogenesis ; GO:0010171 | inferred from sequence or structural similarity with TwdlD proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity with TwdlD "TwdlQ, CG14250" IPR004145:Domain of unknown function DUF243 CG14250 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0028046 l(3)S096901b lethal (3) S096901b http://flybase.org/reports/FBgn0028046 gene - - - "0969/01, l(3)S096901, l(3)S096901b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0051496 CG31496 - http://flybase.org/reports/FBgn0051496 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from sequence model "CG14604, CG31496" - CG31496 27-Aug-18 DroID_v2018_08 "Drer\zgc:153681, Drer\nxf1" Scer\MEX67 - Xtro\nxf1 "Mmus\Nxf1, Mmus\Nxf7, Mmus\Nxf2, Mmus\Nxf3" "Hsap\NXF5, Hsap\NXF3, Hsap\NXF1, Hsap\NXF2B, Hsap\NXF2" viable FBgn0027054 CSN4 COP9 signalosome subunit 4 http://flybase.org/reports/FBgn0027054 FBgn0022061 protein_coding_gene NEDD8 activating enzyme activity ; GO:0019781 | inferred from mutant phenotype protein binding ; GO:0005515 | inferred from physical interaction with CSN7 NEDD8-specific protease activity ; GO:0019784 | contributes_to inferred from direct assay transcription regulatory region DNA binding ; GO:0044212 | inferred from direct assay lateral inhibition ; GO:0046331 | inferred from mutant phenotype negative regulation of proteasomal ubiquitin-dependent protein catabolic process ; GO:0032435 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs female germ-line stem cell population maintenance ; GO:0036099 | inferred from mutant phenotype germ cell development ; GO:0007281 | inferred from mutant phenotype protein deneddylation ; GO:0000338 | inferred from mutant phenotype compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from mutant phenotype male germ-line cyst encapsulation ; GO:0048140 | inferred from mutant phenotype protein stabilization ; GO:0050821 | inferred from mutant phenotype COP9 signalosome ; GO:0008180 | inferred from sequence or structural similarity COP9 signalosome ; GO:0008180 | non-traceable author statement cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000091645 COP9 signalosome ; GO:0008180 | inferred from physical interaction with CSN7 COP9 signalosome ; GO:0008180 | inferred from mutant phenotype COP9 signalosome ; GO:0008180 | traceable author statement COP9 signalosome ; GO:0008180 | inferred from direct assay "CSN4, csn4, Dch4, Csn4, DCH4, Cops4, l(2)k08018, CH4, CG8725" "IPR000717:Proteasome component (PCI) domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR011990:Tetratricopeptide-like helical domain" CG8725 27-Aug-18 DroID_v2018_08 Drer\cops4 - Cele\csn-4 Xtro\cops4 Mmus\Cops4 Hsap\COPS4 "lethal,recessive,viable,fertile,female sterile germline-dependent,germline clone,small body,female sterile,chemical sensitive,visible,somatic clone,lethal - all die before end of larval stage,some die during larval stage,partially lethal - majority die,some die during pupal stage" "ovary,germline clone,female germline stem cell,fusome | germline clone,photoreceptor cell,cephalopharyngeal skeleton,trichogen cell,somatic clone,supernumerary,chaeta,mesothoracic tergum" DRSC07350 K 0.884105131 0.660767784 0.84540905 0.454594417 2.89593059 2.872183253 FBgn0025869 C31 C31 http://flybase.org/reports/FBgn0025869 - gene - adult walking behavior ; GO:0007628 | non-traceable author statement - C31 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035909 ergic53 ergic53 http://flybase.org/reports/FBgn0035909 protein_coding_gene - - membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR005052 endomembrane system ; GO:0012505 | inferred from direct assay "l(3)S1760, dergic53, CG6822, dERGIC53, rhea, l(3)s1760, ergic53, ERGIC53" "IPR005052:Legume-like lectin, IPR013320:Concanavalin A-like lectin/glucanase domain" CG6822 27-Aug-18 DroID_v2018_08 Drer\lman1 "Scer\EMP46, Scer\EMP47" Cele\ile-1 "Xtro\lman1, Xtro\cplx3" "Mmus\Lman1, Mmus\Lman1l" "Hsap\LMAN1, Hsap\LMAN1L" "viable,fertile,partially lethal - majority die" FBgn0065132 l(3)SH129 lethal (3) SH129 http://flybase.org/reports/FBgn0065132 gene - - - "l(3)SH129, l(2)SH3 129" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0065729 l(2)SH0556 lethal (2) SH0556 http://flybase.org/reports/FBgn0065729 gene - - - l(2)SH0556 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0267904 CG46192 - http://flybase.org/reports/FBgn0267904 protein_coding_gene - sperm chromatin condensation ; GO:0035092 | inferred from electronic annotation with InterPro:IPR024460 - CG46192 IPR024460:Protamine-like CG46192 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065742 l(2)SH0523 lethal (2) SH0523 http://flybase.org/reports/FBgn0065742 gene - - - "l(2)SH0523, l(2)SH2 0523" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0060848 l(3)S048619a lethal (3) S048619a http://flybase.org/reports/FBgn0060848 gene - - - "0486/19, l(3)S048619a" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0005013 dipp-4 defective in phototaxis plasticity 4 http://flybase.org/reports/FBgn0005013 - gene - - - dipp-4 - - 27-Aug-18 DroID_v2018_08 - - - - - - "neurophysiology defective,visual behavior defective,phototaxis defective" photoreceptor FBgn0028174 l(3)S026420 lethal (3) S026420 http://flybase.org/reports/FBgn0028174 gene - - - "0264/20, l(3)S026420" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0262723 in::mwh - http://flybase.org/reports/FBgn0262723 engineered_fusion_gene - - - in::mwh - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0020364 anon-17Aa anon-17Aa http://flybase.org/reports/FBgn0020364 - gene - - - "1D10, anon-17Aa" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0024141 Bip-p150 Bcd interacting protein p150 http://flybase.org/reports/FBgn0024141 - gene - - - "p150, Bip-p150" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0067104 G5.A G5.A http://flybase.org/reports/FBgn0067104 gene - - - "G5, G5.A" - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,lethal" chaeta FBgn0043984 Su(rst)E304 Su(rst)E304 http://flybase.org/reports/FBgn0043984 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "E304, Su(rst)E304" - - 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0013499 l(1)LB5 lethal (1) LB5 http://flybase.org/reports/FBgn0013499 - gene - - - "LB5, l(1)LB5" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0265652 lncRNA:CR44459 - http://flybase.org/reports/FBgn0265652 non_protein_coding_gene - - - "lincRNA.316, CR44459" - CR44459 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0041769 anon-d35 anon-d35 http://flybase.org/reports/FBgn0041769 gene - - - "d35, anon-d35" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032127 CG13114 - http://flybase.org/reports/FBgn0032127 protein_coding_gene - - chorion ; GO:0042600 | inferred from direct assay CG13114 IPR031806:Protein of unknown function DUF4744 CG13114 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0044399 Scim28 Sensitized chromosome inheritance modifier 28 http://flybase.org/reports/FBgn0044399 gene - female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype - Scim28 - - 27-Aug-18 DroID_v2018_08 - - - - - - "meiotic cell cycle defective,dominant" FBgn0266820 lncRNA:CR45282 - http://flybase.org/reports/FBgn0266820 non_protein_coding_gene - - - CR45282 - CR45282 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035666 Jon65Aii Jonah 65Aii http://flybase.org/reports/FBgn0035666 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "CG6580, Jon65A, SP153, Jon65Aii" "IPR018114:Serine proteases, trypsin family, histidine active site, IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG6580 27-Aug-18 DroID_v2018_08 - - - - "Mmus\C1s1, Mmus\C1s2" - viable FBgn0028408 Drep2 DNA fragmentation factor-related protein 2 http://flybase.org/reports/FBgn0028408 protein_coding_gene nuclease activity ; GO:0004518 | NOT inferred from direct assay neurogenesis ; GO:0022008 | inferred from mutant phenotype negative regulation of neuron death ; GO:1901215 | inferred from genetic interaction with Fmr1 regulation of apoptotic process ; GO:0042981 | inferred from biological aspect of ancestor with PANTHER:PTN000959605 intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR003508 postsynaptic membrane ; GO:0045211 | inferred from direct assay synaptic membrane ; GO:0097060 | inferred from direct assay "drep2, CG1975, anon-WO0118547.168, anon-WO0118547.162, Rep2, Drep-2, Drep2, DREP-2, rep2" IPR003508:CIDE-N domain CG1975 27-Aug-18 DroID_v2018_08 "Drer\cideb, Drer\cidea, Drer\cidec, Drer\dffa" - - "Xtro\cidea, Xtro\cidec" "Mmus\Cideb, Mmus\Cidec, Mmus\Dffa, Mmus\Cidea" "Hsap\CIDEA, Hsap\CIDEC, Hsap\DFFA, Hsap\CIDEB" "viable,fertile,lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" FBgn0262417 mir-316 mir-316 stem loop http://flybase.org/reports/FBgn0262417 miRNA_gene - - - "miR-316, dme-mir-316, mir-316, MIR-316, CR42965, Mir-316, CR33620, dme-miR-316" - CR42965 27-Aug-18 DroID_v2018_08 - - - - - - "visible,viable,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage" "wing,wing margin,wing vein" FBgn0001501 l(1)10Cd lethal (1) 10Cd http://flybase.org/reports/FBgn0001501 - gene - - - l(1)10Cd - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0033308 CG8736 - http://flybase.org/reports/FBgn0033308 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR033778 - - "BcDNA:RH08259, CG8736" IPR033778:Cuticle protein CPCFC CG8736 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0027338 Kap-alpha3 karyopherin alpha3 http://flybase.org/reports/FBgn0027338 "FBgn0024888, FBgn0026235, FBgn0028164" protein_coding_gene protein transporter activity ; GO:0008565 | inferred from biological aspect of ancestor with PANTHER:PTN001153158 nuclear localization sequence binding ; GO:0008139 | inferred from biological aspect of ancestor with PANTHER:PTN001153158 myosin binding ; GO:0017022 | inferred from physical interaction with Myo10A Notch binding ; GO:0005112 | inferred from direct assay mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs positive regulation of NFAT protein import into nucleus ; GO:0051533 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype NLS-bearing protein import into nucleus ; GO:0006607 | inferred from biological aspect of ancestor with PANTHER:PTN001153158 response to UV ; GO:0009411 | inferred from direct assay nuclear pore ; GO:0005643 | inferred from biological aspect of ancestor with PANTHER:PTN001153158 nucleoplasm ; GO:0005654 | inferred from biological aspect of ancestor with PANTHER:PTN001153158 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN001153158 "imp alpha3, Imp alpha-3, imp-alpha3, dKap-alpha3, Kap alpha3, 0335/13, Kap-alpha3, l(3)S033513, imp-a3, CG9423, impalpha3, IMPalpha3, Kpna3, Kapalpha3, Dalpha3, Kap-?3, KAP-ALPHA3, dimpalpha3, Imp-alpha3, alphaKap3, kpn-alpha3, Kpn-alpha3" "IPR000225:Armadillo, IPR002652:Importin-alpha, importin-beta-binding domain, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold, IPR024931:Importin subunit alpha, IPR032413:Atypical Arm repeat" CG9423 27-Aug-18 DroID_v2018_08 "Drer\spag6, Drer\kpna5, Drer\kpna4, Drer\kpna1, Drer\kpna7, Drer\kpna3, Drer\kpna6" Scer\SRP1 "Cele\ima-3, Cele\ima-1" "Xtro\kpna6, Xtro\kpna1, Xtro\kpna4, Xtro\kpna7, Xtro\spag6, Xtro\armc3, Xtro\kpna3, Xtro\kpna2" "Mmus\Kpna3, Mmus\Kpna4, Mmus\Spag6, Mmus\Kpna6, Mmus\Kpna7, Mmus\Kpna1, Mmus\Spag6l, Mmus\Kpna2" "Hsap\KPNA3, Hsap\KPNA5, Hsap\SPAG6, Hsap\KPNA7, Hsap\KPNA1, Hsap\KPNA6, Hsap\KPNA2, Hsap\KPNA4" embryonic stage -- adult stage "viable,fertile,lethal,female,lethal - all die before end of larval stage,some die during larval stage,wild-type,phototaxis defective,somatic clone,visible,heat sensitive,partially lethal - majority die,neuroanatomy defective" "eye,somatic clone,ommatidium,interommatidial bristle,rhabdomere,photoreceptor cell R7,tormogen cell,tergite,mesothoracic tergum" FBgn0085294 CG34265 - http://flybase.org/reports/FBgn0085294 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34265 - CG34265 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000070 Alu Alula http://flybase.org/reports/FBgn0000070 - gene - - - Alu - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,dominant,viable" "alula,wing" FBgn0004228 mex1 midgut expression 1 http://flybase.org/reports/FBgn0004228 - protein_coding_gene - - - "CG7936, mex1" - CG7936 27-Aug-18 DroID_v2018_08 - Scer\ZRG17 - - - Hsap\AP3B1 " embryonic stage | stage 12 , embryonic stage | stage >=12 , embryonic stage | stage >=9 , embryonic stage | stage >=14 , adult stage " " anterior midgut proper primordium

, posterior midgut proper primordium

, embryonic/larval midgut

" "viable,fertile" FBgn0013495 l(1)HA6 lethal (1) HA6 http://flybase.org/reports/FBgn0013495 - gene - - - "HA6, l(1)HA6" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0050390 Sgf29 SAGA-associated factor 29kDa http://flybase.org/reports/FBgn0050390 protein_coding_gene histone acetyltransferase activity ; GO:0004402 | contributes_to inferred from direct assay methylated histone binding ; GO:0035064 | inferred from sequence or structural similarity with HGNC:25156 histone acetylation ; GO:0016573 | inferred from direct assay histone H3 acetylation ; GO:0043966 | inferred from direct assay chromatin remodeling ; GO:0006338 | inferred from direct assay Ada2/Gcn5/Ada3 transcription activator complex ; GO:0005671 | inferred from direct assay SAGA complex ; GO:0000124 | inferred from direct assay Ada2/Gcn5/Ada3 transcription activator complex ; GO:0005671 | inferred from physical interaction with Ada2a nucleus ; GO:0005634 | inferred from direct assay "CG10509, CG30390, dSgf29, Sgf29" IPR010750:SGF29 tudor-like domain CG30390 27-Aug-18 DroID_v2018_08 Drer\sgf29 Scer\SGF29 "Cele\T22B7.4, Cele\Y17G9B.8" Xtro\sgf29 Mmus\Sgf29 Hsap\SGF29 viable FBgn0004054 zen2 zerknullt-related http://flybase.org/reports/FBgn0004054 - protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR017970" - "z2, zpr, CG1048, BG:DS00276.10, zen2" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR020479:Homeobox domain, metazoa" CG1048 27-Aug-18 DroID_v2018_08 "Drer\hoxc3a, Drer\hoxa3a, Drer\mnx1, Drer\gsx1, Drer\hoxb3a, Drer\hoxb6a, Drer\hoxb8b, Drer\hoxb1b, Drer\gsx2, Drer\hoxd4a, Drer\hoxa5a, Drer\hoxc1a, Drer\mnx2a, Drer\hoxa9b, Drer\hoxb2a, Drer\hoxc4a, Drer\hoxc6b, Drer\hoxc6a, Drer\meox2a, Drer\hoxb1a, Drer\gbx2, Drer\hoxb6b, Drer\hoxd3a, Drer\hoxb4a, Drer\hoxc8a, Drer\hoxa4a, Drer\meox2b, Drer\hoxc5a, Drer\hoxa1a, Drer\hoxb7a, Drer\hoxa2b, Drer\pdx1, Drer\hoxb5b, Drer\gbx1, Drer\meox1, Drer\hoxb5a" "Scer\YOX1, Scer\YHP1, Scer\PHO2" "Cele\ceh-12, Cele\ceh-10" "Xtro\hoxc8, Xtro\hoxc3, Xtro\hoxb3, Xtro\hoxd8, Xtro\hoxd3, Xtro\hoxa2, Xtro\mnx1, Xtro\pdx1, Xtro\hoxb8, Xtro\hoxb5, Xtro\hoxc5, Xtro\hoxb2, Xtro\meox2, Xtro\hoxa1, Xtro\gbx2.1, Xtro\hoxb7, Xtro\gsx2, Xtro\hoxb4, Xtro\gsx1, Xtro\hoxd1, Xtro\hoxa5, Xtro\hoxb6, Xtro\hoxc4, Xtro\hoxb1, Xtro\hoxa3, Xtro\gbx2.2" "Mmus\Hoxc6, Mmus\Hoxb2, Mmus\Hoxa3, Mmus\Hoxd1, Mmus\Hoxb6, Mmus\Hoxc8, Mmus\Hoxd4, Mmus\Hoxb7, Mmus\Hoxa4, Mmus\Hoxa6, Mmus\Hoxb4, Mmus\Barx2, Mmus\Meox1, Mmus\Hoxb8, Mmus\Meox2, Mmus\Hoxb3, Mmus\Hoxb5, Mmus\Hoxc4, Mmus\Pdx1, Mmus\Hoxd3, Mmus\Gbx1, Mmus\Hoxb1, Mmus\Hoxa7, Mmus\Hoxc5, Mmus\Gsx1, Mmus\Mnx1, Mmus\Hoxa5, Mmus\Hoxa2, Mmus\Hoxa1, Mmus\Hoxd8, Mmus\Gbx2, Mmus\Gsx2" "Hsap\HOXA4, Hsap\HOXA3, Hsap\HOXD1, Hsap\HOXB4, Hsap\MEOX2, Hsap\HOXB6, Hsap\PDX1, Hsap\HOXD3, Hsap\HOXC4, Hsap\HOXC8, Hsap\HOXA1, Hsap\GBX1, Hsap\HOXC6, Hsap\HOXB5, Hsap\GSX2, Hsap\MNX1, Hsap\HOXA2, Hsap\HOXB3, Hsap\HOXB7, Hsap\HOXC5, Hsap\HOXB1, Hsap\HOXB2, Hsap\HOXB8, Hsap\HOXA7, Hsap\GBX2, Hsap\HOXA5, Hsap\HOXA6, Hsap\HOXD8, Hsap\GSX1, Hsap\HOXD4, Hsap\MEOX1" " embryonic stage | 3.5 hr , embryonic stage | embryonic cycle 14 , embryonic stage | extended germ band , embryonic stage | gastrula , embryonic stage | early , embryonic stage " " dorsal fold

, organism | dorsal & anterior

, amnioserosa

, organism | dorsal

, dorsal ectoderm | restricted

, embryo | dorsal

" lethal FBgn0265643 lncRNA:CR44450 - http://flybase.org/reports/FBgn0265643 non_protein_coding_gene - - - "CR44450, lincRNA.268" - CR44450 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0026368 Sbp6 Su(H)-binding protein 6 http://flybase.org/reports/FBgn0026368 - gene - biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "sbp6, Sbp6" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0019804 ksr::tor ksr::tor http://flybase.org/reports/FBgn0019804 - engineered_fusion_gene - - - ksr::tor - - 27-Aug-18 DroID_v2018_08 - - - - - - "wild-type,visible,dominant" "eye,eye photoreceptor cell,ommatidium,photoreceptor cell R7" FBgn0262472 EP330 - http://flybase.org/reports/FBgn0262472 gene - - - EP330 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001346 l(1)1Ea lethal (1) 1Ea http://flybase.org/reports/FBgn0001346 - gene - - - l(1)1Ea - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage,lethal,recessive,cell lethal,germline clone" FBgn0266862 lncRNA:CR45323 - http://flybase.org/reports/FBgn0266862 non_protein_coding_gene - - - CR45323 - CR45323 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0011204 cue cueball http://flybase.org/reports/FBgn0011204 FBgn0035225 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881 triglyceride homeostasis ; GO:0070328 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype primary spermatocyte growth ; GO:0007285 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from expression pattern inferred from mutant phenotype - "CT5570, CG12086, ms(3)02509, cue" "IPR000033:LDLR class B repeat, IPR000742:EGF-like domain, IPR013032:EGF-like, conserved site, IPR011042:Six-bladed beta-propeller, TolB-like, IPR001881:EGF-like calcium-binding domain" CG12086 27-Aug-18 DroID_v2018_08 "Drer\lrp2a, Drer\lrp1ba, Drer\ldlrad3, Drer\lrp13, Drer\nid2b, Drer\lrp1bb, Drer\lrp1ab" "Scer\APM3, Scer\APM2, Scer\APM1" "Cele\rme-2, Cele\F14B4.1, Cele\lrp-1" - "Mmus\Lrp1b, Mmus\Egf, Mmus\Lrp1, Mmus\Lrp2, Mmus\Ldlrad3" "Hsap\LRP1, Hsap\LDLRAD3, Hsap\EGF, Hsap\LRP1B, Hsap\LRP2, Hsap\LRP5L" "male sterile,recessive,female semi-sterile,viable" "spermatocyte,primary spermatocyte cyst,testis,ovary" FBgn0030577 CG5334 - http://flybase.org/reports/FBgn0030577 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:7112 zinc ion binding ; GO:0008270 | inferred from sequence model protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with HGNC:7112 cellular_component ; GO:0005575 | no biological data available CG5334 "IPR000571:Zinc finger, CCCH-type, IPR001841:Zinc finger, RING-type, IPR017907:Zinc finger, RING-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR018957:Zinc finger, C3HC4 RING-type" CG5334 27-Aug-18 DroID_v2018_08 "Drer\mkrn4, Drer\rnf141, Drer\mkrn2, Drer\mkrn1" Scer\LEE1 "Cele\Y55F3AM.6, Cele\ccch-1" "Xtro\mkrn1, Xtro\mkrn2, Xtro\rnf141, Xtro\mkrn3" "Mmus\Mkrn3, Mmus\Mkrn1, Mmus\Mkrn2, Mmus\Rnf141" "Hsap\MKRN1, Hsap\MKRN2, Hsap\RNF141, Hsap\MKRN3" FBgn0032031 CG13390 - http://flybase.org/reports/FBgn0032031 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR005225, InterPro:IPR006073, InterPro:IPR006169, InterPro:IPR014100, InterPro:IPR031167 magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR014100 GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR014100" - - CG13390 "IPR005225:Small GTP-binding protein domain, IPR006073:GTP binding domain, IPR006169:GTP1/OBG domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR014100:GTP-binding protein Obg/CgtA, IPR031167:OBG-type guanine nucleotide-binding (G) domain" CG13390 27-Aug-18 DroID_v2018_08 "Drer\gtpbp10, Drer\mtg2" "Scer\MTG2, Scer\MSS1" "Cele\C26E6.12, Cele\M01E5.2" "Xtro\gtpbp10, Xtro\mtg2" "Mmus\Gtpbp10, Mmus\Mtg2" "Hsap\GTPBP10, Hsap\MTG2" viable FBgn0086075 snoRNA:Me28S-G3253 - http://flybase.org/reports/FBgn0086075 snoRNA_gene - - - "snoRNA:28S-G3253, 28S-Gm3253, CR34704, snoRNA:Me28S-G3253, Me28S-G3253" - CR34704 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262396 mir-314 mir-314 stem loop http://flybase.org/reports/FBgn0262396 miRNA_gene - - - "dme-mir-314, mir-314, miR-314, CR42933, CR33618, dme-miR-314-5p" - CR42933 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0039003 wfs1 wolfram syndrome 1 http://flybase.org/reports/FBgn0039003 protein_coding_gene - - - "CG4917, wfs1" IPR026209:Wolframin family CG4917 27-Aug-18 DroID_v2018_08 "Drer\wfs1a, Drer\wfs1b" - - Xtro\wfs1 Mmus\Wfs1 Hsap\WFS1 "viable,fertile" DRSC15676 K -0.271374309 0.719126685 -0.050197093 0.042517314 2.625593023 0.835816879 FBgn0036608 CG13040 - http://flybase.org/reports/FBgn0036608 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13040 IPR007614:Retinin-like protein CG13040 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0062528 l(3)88EFd lethal (3) 88EFd http://flybase.org/reports/FBgn0062528 gene - - - l(3)88EFd - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0000587 E(S) Enhancer of Star http://flybase.org/reports/FBgn0000587 - gene - - - E(S) - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive" eye FBgn0259286 C575 - http://flybase.org/reports/FBgn0259286 gene - - - C575 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible wing FBgn0053222 CR33222 - http://flybase.org/reports/FBgn0053222 pseudogene_attribute - - - "CG33222, CR11386, CR33222" - CR33222 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039925 Kif3C Kinesin family member 3C http://flybase.org/reports/FBgn0039925 protein_coding_gene "microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR001752 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001752, InterPro:IPR019821 ATP-dependent microtubule motor activity, minus-end-directed ; GO:0008569 | non-traceable author statement microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity ATPase activity ; GO:0016887 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 microtubule motor activity ; GO:0003777 | inferred from biological aspect of ancestor with PANTHER:PTN000648413" neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity microtubule-based movement ; GO:0007018 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 kinesin complex ; GO:0005871 | inferred from sequence or structural similarity kinesin complex ; GO:0005871 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 "CG17461, DmKIF3C, KIF3C, CG17459, Kif3C, Kif3c, KIF3Cdm, DmKif3C, KIF 3C, CP38609, KIF 24, KIF17" "IPR001752:Kinesin motor domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR019821:Kinesin motor domain, conserved site" CG17461 27-Aug-18 DroID_v2018_08 "Drer\LOC100333558, Drer\kif3b, Drer\kif17, Drer\kif26aa, Drer\LOC100331925, Drer\si:dkey-86l18.8, Drer\kif3cb, Drer\kif26bb, Drer\kif26ba, Drer\kifc1, Drer\kif3a, Drer\kif15" "Scer\CIN8, Scer\KAR3, Scer\KIP1" "Cele\klp-11, Cele\osm-3, Cele\klp-20" "Xtro\kif3a, Xtro\kif3b, Xtro\kif9, Xtro\kif3c, Xtro\kif26a, Xtro\kif15" "Mmus\Kif9, Mmus\Kif3c, Mmus\Kif26b, Mmus\Kifc1, Mmus\Gm1305, Mmus\Kif26a, Mmus\Kifc5b, Mmus\Kif6, Mmus\Kif12, Mmus\Kif3b, Mmus\Kif17, Mmus\Kif15, Mmus\Kif3a" "Hsap\KIF17, Hsap\KIFC1, Hsap\KIF26A, Hsap\KIF15, Hsap\KIF3C, Hsap\KIF9, Hsap\KIF26B, Hsap\KIF3A, Hsap\KIF3B, Hsap\KIF6, Hsap\KIF12" viable FBgn0001230 Hsp68 Heat shock protein 68 http://flybase.org/reports/FBgn0001230 - protein_coding_gene unfolded protein binding ; GO:0051082 | inferred from sequence or structural similarity with UniProtKB:P38646 neurogenesis ; GO:0022008 | inferred from mutant phenotype response to starvation ; GO:0042594 | inferred from mutant phenotype protein folding ; GO:0006457 | inferred from sequence or structural similarity with UniProtKB:P38646 determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:P38646 lipid particle ; GO:0005811 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay "hsp68, Hsp-68, HSP68, 68, CG5436, Hsp68, HSP68_DROME, DmHsp68" "IPR018181:Heat shock protein 70, conserved site, IPR013126:Heat shock protein 70 family, IPR029048:Heat shock protein 70kD, C-terminal domain, IPR029047:Heat shock protein 70kD, peptide-binding domain" CG5436 27-Aug-18 DroID_v2018_08 "Drer\hspa13, Drer\hspa5, Drer\hsp70.2, Drer\si:dkey-4p15.3, Drer\hsp70.1, Drer\hspa12b, Drer\hspa14, Drer\hspa8, Drer\hsc70, Drer\si:ch211-199o1.2, Drer\nckap1, Drer\hspa12a, Drer\hsp70l" "Scer\SSA1, Scer\SSB2, Scer\SSA4, Scer\SSA2, Scer\SSA3, Scer\KAR2, Scer\SSQ1, Scer\SSB1, Scer\SSZ1" "Cele\F11F1.1, Cele\hsp-4, Cele\hsp-3, Cele\F44E5.4, Cele\gex-3, Cele\hsp-70, Cele\F44E5.5, Cele\hsp-1" "Xtro\hspa1l, Xtro\hspa2, Xtro\hsp70, Xtro\hspa8, Xtro\hspa5, Xtro\hspa1b, Xtro\hspa14, Xtro\nckap1, Xtro\hspa1a, Xtro\hspa13, Xtro\hspa12b, Xtro\nckap1l" "Mmus\Hspa1b, Mmus\Hspa14, Mmus\Hspa12b, Mmus\Hspa1a, Mmus\Hspa2, Mmus\Hspa13, Mmus\Hspa1l, Mmus\Hspa12a, Mmus\Nckap1l, Mmus\Hspa8, Mmus\Hspa5, Mmus\Nckap1" "Hsap\HSPA8, Hsap\HSPA5, Hsap\HSPA12B, Hsap\HSPA6, Hsap\NCKAP1L, Hsap\NCKAP1, Hsap\HSPA12A, Hsap\HSPA1L, Hsap\HSPA13, Hsap\HSPA1B, Hsap\HSPA1A, Hsap\HSPA2, Hsap\HSPA14" "chemical resistant,long lived,starvation stress response defective,body color defective,partially lethal - majority die,some die during pupal stage,lethal,neuroanatomy defective" "mesothoracic tergum,embryonic/larval neuroblast,ganglion mother cell" FBgn0045497 Gr22e Gustatory receptor 22e http://flybase.org/reports/FBgn0045497 protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 taste receptor activity ; GO:0008527 | non-traceable author statement sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of taste ; GO:0050909 | non-traceable author statement response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 integral component of membrane ; GO:0016021 | non-traceable author statement neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 "Gr2940.1, CG31936, Gr22e, GR22e" IPR013604:7TM chemoreceptor CG31936 27-Aug-18 DroID_v2018_08 - - "Cele\gur-3, Cele\lite-1" - - - viable DRSC20912 IE 1.536077611 0.764820933 -4.568871423 1.353590474 -0.063108385 0.452981509 FBgn0259666 B0729 - http://flybase.org/reports/FBgn0259666 gene - - - B0729 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible wing FBgn0267489 PRY polycystine-related-Y http://flybase.org/reports/FBgn0267489 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR000203 cellular_component ; GO:0005575 | no biological data available "CG40930, PRY, CG41367, CG42619, CG45787" "IPR000203:GPS motif, IPR001024:PLAT/LH2 domain, IPR002859:PKD/REJ-like domain" CG45787 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031632 CG15628 - http://flybase.org/reports/FBgn0031632 protein_coding_gene N-acetyltransferase activity ; GO:0008080 | inferred from electronic annotation with InterPro:IPR000182 - - "anon-WO02059370.23, CG15628" "IPR000182:GNAT domain, IPR016181:Acyl-CoA N-acyltransferase, IPR013653:FR47-like" CG15628 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-76k16.6, Drer\si:dkey-76k16.5, Drer\si:ch73-106k19.2" - Cele\ZK185.3 - - Hsap\GLYATL3 "viable,fertile,body color defective" mesothoracic tergum DRSC00256 K 0.266786191 1.84930585 FBgn0026080 Tip60 Tat interactive protein 60kDa http://flybase.org/reports/FBgn0026080 - protein_coding_gene histone acetyltransferase activity ; GO:0004402 | inferred from mutant phenotype histone acetyltransferase activity ; GO:0004402 | inferred from direct assay "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR002717 regulation of synaptic plasticity ; GO:0048167 | inferred from direct assay histone H4 acetylation ; GO:0043967 | inferred from mutant phenotype histone exchange ; GO:0043486 | inferred from direct assay cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype regulation of gene expression ; GO:0010468 | inferred from mutant phenotype regulation of terminal button organization ; GO:2000331 | inferred from direct assay nervous system development ; GO:0007399 | inferred from mutant phenotype negative regulation of neuron apoptotic process ; GO:0043524 | inferred from mutant phenotype histone acetylation ; GO:0016573 | inferred from direct assay" polytene chromosome interband ; GO:0005705 | inferred from direct assay NuA4 histone acetyltransferase complex ; GO:0035267 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay histone acetyltransferase complex ; GO:0000123 | inferred from physical interaction with pont "CG6121, dTip60, dmHAG405, EG0007.7, DmEG0007.7, EG:EG0007.7, Tip60, dTIP60, Dmel/TIP60, Dmel\TIP60, 6121, TIP60, TIP-60" "IPR000953:Chromo/chromo shadow domain, IPR002717:Histone acetyltransferase domain, MYST-type, IPR016181:Acyl-CoA N-acyltransferase, IPR016197:Chromo domain-like, IPR025995:RNA binding activity-knot of a chromodomain" CG6121 27-Aug-18 DroID_v2018_08 "Drer\kat8, Drer\kat5b, Drer\kat7a, Drer\kat7b, Drer\kat6a, Drer\kat6b, Drer\kat5a" "Scer\SAS2, Scer\SAS3, Scer\ESA1" "Cele\mys-2, Cele\mys-1, Cele\lsy-12, Cele\mys-4" "Xtro\kat5, Xtro\kat7, Xtro\kat8, Xtro\trim69.1, Xtro\xnf7" "Mmus\Kat6b, Mmus\Kat5, Mmus\Kat8, Mmus\Kat7, Mmus\Kat6a" "Hsap\KAT5, Hsap\KAT8, Hsap\KAT6A, Hsap\KAT7, Hsap\KAT6B" "locomotor behavior defective,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,lethal,majority die during third instar larval stage,increased mortality during development,partially lethal - majority die,increased cell death,viable,heat sensitive,visible,fertile,partially,cytokinesis defective,cell lethal" "terminal bouton,type I bouton,ectopic,type Ib terminal bouton | ectopic,terminal boutonMef2.247,type Ib terminal bouton | ectopicMef2.247,type Is terminal boutonMef2.247,embryonic/larval brain | third instar larval stage,wing,wing vein,wing disc,trichogen cell" DRSC18661 E -0.55123146 -0.745855978 2.891373343 -2.462615533 0.773167995 -0.238591028 FBgn0083286 E(smoDN)2117 Enhancer of smoDN 2117 http://flybase.org/reports/FBgn0083286 gene - - - E(smoDN)2117 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001794 l(1)Mb26 lethal (1) Mb26 http://flybase.org/reports/FBgn0001794 - gene - - - l(1)Mb26 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" FBgn0261707 asRNA:CR42743 - http://flybase.org/reports/FBgn0261707 non_protein_coding_gene - - - CR42743 - CR42743 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0010414 SerT Serotonin transporter http://flybase.org/reports/FBgn0010414 FBgn0011835 protein_coding_gene monoamine transmembrane transporter activity ; GO:0008504 | inferred from direct assay serotonin transmembrane transporter activity ; GO:0015222 | inferred from direct assay cation channel activity ; GO:0005261 | inferred from direct assay dopamine:sodium symporter activity ; GO:0005330 | inferred from biological aspect of ancestor with PANTHER:PTN000746001 serotonin uptake ; GO:0051610 | inferred from direct assay dopamine uptake involved in synaptic transmission ; GO:0051583 | inferred from biological aspect of ancestor with PANTHER:PTN000746001 serotonin transport ; GO:0006837 | inferred from direct assay monoamine transport ; GO:0015844 | inferred from direct assay phagocytosis ; GO:0006909 | inferred from mutant phenotype axon ; GO:0030424 | inferred from direct assay axon terminus ; GO:0043679 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with HGNC:11050 "dSERT, SERT, dSerT, dSERT1, dSert, Sert, CG4545, SerT, DmSERT, DmSerT, dsert, serT, dmSERT" IPR000175:Sodium:neurotransmitter symporter CG4545 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-132b12.1, Drer\slc6a13l, Drer\slc6a1a, Drer\slc6a6a, Drer\slc6a2, Drer\slc6a13, Drer\slc6a13, Drer\slc6a19a.1, Drer\slc6a1b, Drer\slc6a19b, Drer\slc6a1l, Drer\slc6a19a.2, Drer\si:ch211-132b12.6, Drer\slc6a4a, Drer\slc6a11a, Drer\slc6a4b, Drer\slc6a5, Drer\si:ch211-132b12.2, Drer\slc6a14, Drer\slc6a15, Drer\slc6a8, Drer\slc6a16b, Drer\si:ch211-117c9.5, Drer\slc6a17, Drer\slc6a18, Drer\slc6a6b, Drer\slc6a9, Drer\slc6a16a, Drer\zgc:158225" - "Cele\mod-5, Cele\snf-6, Cele\dat-1, Cele\snf-3, Cele\snf-10, Cele\snf-11" "Xtro\slc6a17, Xtro\slc6a14.2, Xtro\slc6a9, Xtro\slc6a1, Xtro\slc6a8, Xtro\slc6a13, Xtro\slc6a5, Xtro\LOC100127682, Xtro\slc6a3, Xtro\slc6a6, Xtro\slc6a19, Xtro\slc6a15, Xtro\slc6a12, Xtro\slc6a7, Xtro\slc6a4, Xtro\slc6a16, Xtro\slc6a2" "Mmus\Slc6a4, Mmus\Slc6a6, Mmus\Slc6a12, Mmus\Slc6a20a, Mmus\Slc6a19, Mmus\Slc6a18, Mmus\Slc6a2, Mmus\Slc6a21, Mmus\Slc6a9, Mmus\Slc6a5, Mmus\Slc6a8, Mmus\Slc6a20b, Mmus\Slc6a7, Mmus\Slc6a17, Mmus\Slc6a13, Mmus\Slc6a11, Mmus\Slc6a14, Mmus\Slc6a1, Mmus\Slc6a15, Mmus\Slc6a3, Mmus\Slc6a16" "Hsap\SLC6A1, Hsap\SLC6A19, Hsap\SLC6A11, Hsap\SLC6A7, Hsap\SLC6A8, Hsap\SLC6A14, Hsap\SLC6A9, Hsap\SLC6A6, Hsap\SLC6A20, Hsap\SLC6A13, Hsap\SLC6A12, Hsap\SLC6A16, Hsap\SLC6A5, Hsap\SLC6A15, Hsap\SLC6A3, Hsap\SLC6A2, Hsap\SLC6A4, Hsap\SLC6A17, Hsap\SLC6A18" " larval stage , adult stage , embryonic stage | stage 15-17 " " larval central nervous system | restricted

, adult head

, embryonic central nervous system | restricted

" viable DRSC04655 I 0.893348037 -2.124372974 0.535584996 0.760108681 0.314793031 0.662334174 FBgn0038690 CG11703 - http://flybase.org/reports/FBgn0038690 protein_coding_gene - potassium ion transport ; GO:0006813 | inferred from electronic annotation with InterPro:IPR000402 sodium ion transport ; GO:0006814 | inferred from electronic annotation with InterPro:IPR000402 sodium:potassium-exchanging ATPase complex ; GO:0005890 | inferred from electronic annotation with InterPro:IPR000402 "JYbeta2, anon-WO0140519.49, CG11703" IPR000402:Sodium/potassium-transporting ATPase subunit beta CG11703 27-Aug-18 DroID_v2018_08 "Drer\atp1b2a, Drer\atp1b1b, Drer\atp1b2b, Drer\atp1b3b, Drer\atp1b3a, Drer\atp1b4, Drer\atp1b1a" - "Cele\nkb-2, Cele\nkb-1, Cele\nkb-3" "Xtro\atp1b1, Xtro\atp1b3, Xtro\atp1b4, Xtro\atp1b2, Xtro\atp4b" "Mmus\Atp1b1, Mmus\Atp1b3, Mmus\Atp1b2, Mmus\Atp4b, Mmus\Atp1b4" "Hsap\ATP1B1, Hsap\ATP1B4, Hsap\ATP1B3, Hsap\ATP4B, Hsap\ATP1B2" viable FBgn0000688 flrdL flight reduced L http://flybase.org/reports/FBgn0000688 - gene molecular_function ; GO:0003674 | no biological data available flight behavior ; GO:0007629 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available flrdL - - 27-Aug-18 DroID_v2018_08 - - - - - - "hypoactive,flight defective" FBgn0062694 EP1236 EP1236 http://flybase.org/reports/FBgn0062694 gene - - - "EP(2)1236, EP1236" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262606 lncRNA:CR43132 - http://flybase.org/reports/FBgn0262606 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CR43132, CG43132, lincRNA.1005, mdcds_55191" - CR43132 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065433 l(2)SH1482 lethal (2) SH1482 http://flybase.org/reports/FBgn0065433 gene - - - "l(2)SH1482, l(2)SH2 1482" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0001438 l(1)7Bf lethal (1) 7Bf http://flybase.org/reports/FBgn0001438 - gene - - - "l(1)GF320, l(1)7Bf" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0046793 CG32236 - http://flybase.org/reports/FBgn0046793 protein_coding_gene - - - "NEST:bs27g09, BcDNA:GH16763, CG32236" "IPR029000:Cyclophilin-like domain, IPR029488:Hemingway/KIAA1430" CG32236 27-Aug-18 DroID_v2018_08 "Drer\ppifb, Drer\ppiaa, Drer\ppiab, Drer\ppifa" "Scer\CPR3, Scer\CPR1" - "Xtro\ppia, Xtro\ppif" "Mmus\Ranbp2, Mmus\Ppif, Mmus\Ppia" "Hsap\PPIAL4A, Hsap\LOC105371242, Hsap\PPIAL4D, Hsap\PPIAL4E, Hsap\PPIAL4C, Hsap\PPIF, Hsap\RANBP2, Hsap\PPIA, Hsap\PPIAL4G" viable DRSC08117 I 1.54780742 0.302279955 0.014388703 0.000905362 0.9071219 -0.000221745 FBgn0267510 2SrRNA-Psi:CR45850 2S ribosomal RNA pseudogene:CR45850 http://flybase.org/reports/FBgn0267510 pseudogene_attribute - - - "2SrRNA-Psi:CR45850, CR45850" - CR45850 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0027214 l(1)G0332 lethal (1) G0332 http://flybase.org/reports/FBgn0027214 - gene - - - l(1)G0332 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0265677 lncRNA:CR44484 - http://flybase.org/reports/FBgn0265677 non_protein_coding_gene - - - "lincRNA.20, CR44484" - CR44484 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037024 tzn tenzing norgay http://flybase.org/reports/FBgn0037024 protein_coding_gene hydroxyacylglutathione hydrolase activity ; GO:0004416 | inferred from electronic annotation with InterPro:IPR017782 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione ; GO:0019243 | inferred from electronic annotation with InterPro:IPR017782 response to hypoxia ; GO:0001666 | inferred from mutant phenotype microtubule associated complex ; GO:0005875 | inferred from direct assay "CG4365, tzn" "IPR001279:Metallo-beta-lactamase, IPR017782:Hydroxyacylglutathione hydrolase, IPR032282:Hydroxyacylglutathione hydrolase, C-terminal domain" CG4365 27-Aug-18 DroID_v2018_08 "Drer\tmem104, Drer\hagh, Drer\mblac2, Drer\pnkd" "Scer\GLO2, Scer\GLO4" "Cele\Y17G7B.3, Cele\C03A3.2" "Xtro\haghl, Xtro\lactb2, Xtro\mblac2, Xtro\pnkd, Xtro\hagh, Xtro\tmem104" "Mmus\Pnkd, Mmus\Mblac2, Mmus\Tmem104, Mmus\Lactb2, Mmus\Haghl, Mmus\Hagh" "Hsap\HAGHL, Hsap\MBLAC2, Hsap\PNKD, Hsap\HAGH, Hsap\LACTB2, Hsap\TMEM104" viable DRSC11755 I 2.252649256 0.202467921 0.21434577 -0.178385661 0.23953024 -0.245308299 FBgn0002252 l(3)68Ed lethal (3) 68Ed http://flybase.org/reports/FBgn0002252 - gene - - - "rsg14, l(3)rsg14, l(3)68Ed" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0019624 COX5A Cytochrome c oxidase subunit 5A http://flybase.org/reports/FBgn0019624 FBgn0023019 protein_coding_gene cytochrome-c oxidase activity ; GO:0004129 | inferred from sequence or structural similarity with UniProtKB:P20674 cytochrome-c oxidase activity ; GO:0004129 | inferred from biological aspect of ancestor with PANTHER:PTN000367750 "mitochondrial electron transport, cytochrome c to oxygen ; GO:0006123 | inferred from sequence or structural similarity with UniProtKB:P20674 negative regulation of neuroblast proliferation ; GO:0007406 | inferred from mutant phenotype positive regulation of cell cycle ; GO:0045787 | inferred from mutant phenotype mitochondrial electron transport, cytochrome c to oxygen ; GO:0006123 | inferred from biological aspect of ancestor with PANTHER:PTN000367750" mitochondrial respiratory chain complex IV ; GO:0005751 | inferred from sequence or structural similarity with UniProtKB:P20674 lipid particle ; GO:0005811 | inferred from direct assay mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial respiratory chain complex IV ; GO:0005751 | inferred from biological aspect of ancestor with PANTHER:PTN000367750 "COX, Va, CoVa, tend, CG14724, COXA_DROME, cova, COXA, COX5A, Cox5a" "IPR003204:Cytochrome c oxidase, subunit Va/VI" CG14724 27-Aug-18 DroID_v2018_08 "Drer\cox5aa, Drer\cox5ab" Scer\COX6 Cele\cco-2 Xtro\cox5a Mmus\Cox5a Hsap\COX5A "lethal,recessive,mitotic cell cycle defective,somatic clone,increased cell number,visible,body color defective,partially lethal - majority die,some die during pupal stage" "eye,somatic clone,lens,eye disc posterior to the morphogenetic furrow,cone cell,ommatidial precursor cluster,lamellocyte | third instar larval stage,eye disc,trichogen cell,mesothoracic tergum" DRSC16611 IK -1.158527569 -1.69573182 -1.018231422 -0.830830332 1.678435299 0.731583849 FBgn0019668 mwr more wright http://flybase.org/reports/FBgn0019668 - gene molecular_function ; GO:0003674 | no biological data available female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mwr - - 27-Aug-18 DroID_v2018_08 - - - - - - "meiotic cell cycle defective,recessive,lethal,maternal effect,partially" FBgn0041741 l(2)44Fr lethal (2) 44Fr http://flybase.org/reports/FBgn0041741 gene - - - l(2)44Fr - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0032888 CheB38c Chemosensory protein B 38c http://flybase.org/reports/FBgn0032888 protein_coding_gene lipid binding ; GO:0008289 | inferred from sequence alignment with HGNC:14537 detection of pheromone ; GO:0043695 | inferred from expression pattern sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with CheB42a extracellular space ; GO:0005615 | inferred from sequence or structural similarity with CheB42a extracellular region ; GO:0005576 | inferred from sequence model "CG14405, CheB38c" "IPR006601:Uncharacterised protein family DM11, Drosophila melanogaster, IPR010512:Protein of unknown function DUF1091" CG14405 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030812 wcy wacky http://flybase.org/reports/FBgn0030812 protein_coding_gene molecular_function ; GO:0003674 | no biological data available negative regulation of autophagy ; GO:0010507 | inferred from mutant phenotype positive regulation of TORC1 signaling ; GO:1904263 | inferred from mutant phenotype habituation ; GO:0046959 | inferred from mutant phenotype lysosome ; GO:0005764 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "BP1032, CG34014, CG8949, wcy, XE14" IPR001202:WW domain CG8949 27-Aug-18 DroID_v2018_08 "Drer\wacb, Drer\waca" - "Cele\Y40B1A.1, Cele\Y40B1A.2" Xtro\wac Mmus\Wac Hsap\WAC FBgn0028134 l(3)S050407b lethal (3) S050407b http://flybase.org/reports/FBgn0028134 gene - - - "0504/07, l(3)S050407b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0262004 CG42822 - http://flybase.org/reports/FBgn0262004 protein_coding_gene - - - "CG42822, CG34035, BP1011" - CG42822 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0083951 CG34115 - http://flybase.org/reports/FBgn0083951 protein_coding_gene - - - CG34115 - CG34115 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263516 mir-4958 mir-4958 stem loop http://flybase.org/reports/FBgn0263516 miRNA_gene - - - "mir-4958, CR43501, dme-mir-4958" - CR43501 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001380 l(1)2Bl lethal (1) 2Bl http://flybase.org/reports/FBgn0001380 - gene - - - l(1)2Bl - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0040812 CG8750 - http://flybase.org/reports/FBgn0040812 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG8750 - CG8750 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0005522 l(2)52Db lethal (2) 52Db http://flybase.org/reports/FBgn0005522 - gene - - - l(2)52Db - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031453 Bacc Bacchus http://flybase.org/reports/FBgn0031453 protein_coding_gene - inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay "CG9894, clone 2.54, anon-EST:Liang-2.54, Bacc" - CG9894 27-Aug-18 DroID_v2018_08 - - - - - - "chemical resistant,dominant,viable,behavior defective,recessive,partially lethal - majority die,fertile" FBgn0001349 l(1)1Ed lethal (1) 1Ed http://flybase.org/reports/FBgn0001349 - gene - - - l(1)1Ed - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0042213 CG18731 - http://flybase.org/reports/FBgn0042213 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG18731 IPR028227:Uncharacterised protein family UPF0449 CG18731 27-Aug-18 DroID_v2018_08 Drer\si:ch73-238c9.1 - - Xtro\c19orf25 Mmus\2310011J03Rik Hsap\C19orf25 viable DRSC15377 K 0.122779763 1.181857024 -0.310698265 -0.210586874 0.689266881 1.872992678 FBgn0001467 l(1)7Fd lethal (1) 7Fd http://flybase.org/reports/FBgn0001467 - gene - - - "l(1)VA67, l(1)7Fd" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,cell lethal,germline clone" FBgn0266868 lncRNA:CR45329 - http://flybase.org/reports/FBgn0266868 non_protein_coding_gene - - - CR45329 - CR45329 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0011976 tRNA:Ser-CGA-1-2 transfer RNA:Serine-CGA 1-2 http://flybase.org/reports/FBgn0011976 "FBgn0003826, FBgn0011968, FBgn0011973, FBgn0052623, FBgn0060062" tRNA_gene UCG codon-amino acid adaptor activity ; GO:0033408 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033408 cytosol ; GO:0005829 | inferred by curator from GO:0033408 "444-2, Ser-tRNA-4, tRNA-Ser, tRNA[Ser], Ser tRNA[Ser], AE002593.trna3-SerCGA, tRNA:S:CGA:AE002593-b, CR32623, tRNA:ser, tRNA:S, tRNA:ser4, tRNA:S4, tRNA:ser4:12Eb, tRNA[[Ser]], chrX.trna7-SerCGA, tRNA-Ser-CGA-1-2, tRNA:Ser-CGA-1-2, tRNA:S4:12Eb, UCG" - CR32623 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0028540 CG9008 - http://flybase.org/reports/FBgn0028540 protein_coding_gene "isomerase activity ; GO:0016853 | inferred from electronic annotation with InterPro:IPR008183 carbohydrate binding ; GO:0030246 | inferred from electronic annotation with InterPro:IPR011013, InterPro:IPR014718" "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR008183, InterPro:IPR011013, InterPro:IPR014718 Golgi organization ; GO:0007030 | inferred from mutant phenotype lipid particle organization ; GO:0034389 | inferred from mutant phenotype defense response to virus ; GO:0051607 | inferred from mutant phenotype" - "BG:DS00797.2, CG9008" "IPR025532:Glucose-6-phosphate 1-epimerase, IPR008183:Aldose 1-/Glucose-6-phosphate 1-epimerase, IPR011013:Galactose mutarotase-like domain, IPR014718:Glycoside hydrolase-type carbohydrate-binding" CG9008 27-Aug-18 DroID_v2018_08 - Scer\YMR099C - - - - "lethal,visible,body color defective,partially lethal - majority die,some die during pupal stage" "microchaeta & mesothoracic tergumë±Tub84B.PL,trichogen cell,mesothoracic tergum" FBgn0264738 CG43996 - http://flybase.org/reports/FBgn0264738 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43996, CG12433" - CG43996 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0036923 CG17732 - http://flybase.org/reports/FBgn0036923 protein_coding_gene - - - CG17732 - CG17732 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0265210 ninaE::Btau\RHO - http://flybase.org/reports/FBgn0265210 engineered_fusion_gene - - - ninaE::Btau\RHO - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266798 asRNA:CR45260 - http://flybase.org/reports/FBgn0266798 non_protein_coding_gene - - - CR45260 - CR45260 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0062611 Mod(var)1310 Mod(var)1310 http://flybase.org/reports/FBgn0062611 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "1310, Mod(var)1310" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive,suppressor of variegation,non-enhancer of variegation,non-suppressor of variegation" FBgn0016841 l(1)N1 lethal (1) N1 http://flybase.org/reports/FBgn0016841 - gene - - - "l(1)N1, N1" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0032595 CG17996 - http://flybase.org/reports/FBgn0032595 protein_coding_gene copper ion binding ; GO:0005507 | inferred from sequence or structural similarity with SGD:S000001620 mitochondrial respiratory chain complex IV assembly ; GO:0033617 | inferred from sequence or structural similarity with SGD:S000001620 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN001884832 mitochondrial intermembrane space ; GO:0005758 | inferred from sequence or structural similarity with SGD:S000001620 "BcDNA:GM20557, CG17996" IPR013892:Cytochrome c oxidase biogenesis protein Cmc1-like CG17996 27-Aug-18 DroID_v2018_08 Drer\cmc1 Scer\CMC1 Cele\F01F1.2 Xtro\cmc1 Mmus\Cmc1 Hsap\CMC1 FBgn0052268 Drsl6 Drosomycin-like 6 http://flybase.org/reports/FBgn0052268 protein_coding_gene molecular_function ; GO:0003674 | no biological data available defense response to fungus ; GO:0050832 | inferred from sequence or structural similarity with Drs extracellular region ; GO:0005576 | inferred from sequence or structural similarity with Drs inferred from sequence model "Dro6, CG11520, Dro-I, CG10815, CG32268, Drs-lI, Drsl6, dro6" "IPR003614:Knottin, scorpion toxin-like" CG32268 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0267378 sau sauron http://flybase.org/reports/FBgn0267378 protein_coding_gene phosphatidylinositol-4-phosphate binding ; GO:0070273 | inferred from direct assay phosphatidylinositol-3-phosphate binding ; GO:0032266 | inferred from direct assay Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab5 inferred from physical interaction with Rab11 phosphatidic acid binding ; GO:0070300 | inferred from direct assay phosphatidylinositol-4-phosphate binding ; GO:0070273 | inferred from biological aspect of ancestor with PANTHER:PTN000294961 phosphatidylinositol-5-phosphate binding ; GO:0010314 | inferred from direct assay "male meiosis cytokinesis ; GO:0007112 | inferred from mutant phenotype Golgi vesicle budding ; GO:0048194 | inferred from biological aspect of ancestor with PANTHER:PTN000294961 spindle assembly involved in male meiosis ; GO:0007053 | inferred from mutant phenotype retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | inferred from biological aspect of ancestor with PANTHER:PTN000294961 Golgi organization ; GO:0007030 | inferred from biological aspect of ancestor with PANTHER:PTN000294961 actomyosin contractile ring assembly ; GO:0000915 | inferred from mutant phenotype spindle assembly ; GO:0051225 | inferred from mutant phenotype retrograde transport, vesicle recycling within Golgi ; GO:0000301 | inferred from mutant phenotype mitotic spindle assembly ; GO:0090307 | inferred from mutant phenotype cleavage furrow formation ; GO:0036089 | inferred from mutant phenotype Golgi organization ; GO:0007030 | inferred from mutant phenotype smoothened signaling pathway ; GO:0007224 | inferred from mutant phenotype meiosis II cytokinesis ; GO:0007111 | inferred from mutant phenotype mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype Golgi to plasma membrane protein transport ; GO:0043001 | inferred from biological aspect of ancestor with PANTHER:PTN000294961 meiosis I cytokinesis ; GO:0007110 | inferred from mutant phenotype" Golgi apparatus ; GO:0005794 | inferred from direct assay cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000294961 trans-Golgi network ; GO:0005802 | inferred from biological aspect of ancestor with PANTHER:PTN000294961 Golgi cisterna ; GO:0031985 | inferred from sequence or structural similarity with UniProtKB:Q9H4A6 cleavage furrow ; GO:0032154 | inferred from direct assay Golgi cisterna ; GO:0031985 | inferred from biological aspect of ancestor with PANTHER:PTN000294961 "GOLPH3, sau, CG7085, l(2)s5379, rti, BEST:LD28579, BcDNA:LD10657, Rotini" IPR008628:Golgi phosphoprotein 3-like CG7085 27-Aug-18 DroID_v2018_08 "Drer\golph3l, Drer\golph3, Drer\si:dkey-27b3.2" Scer\VPS74 Cele\Y47G6A.18 "Xtro\golph3, Xtro\golph3l" "Mmus\Golph3l, Mmus\Golph3" "Hsap\GOLPH3, Hsap\GOLPH3L" DRSC00694 I 0.424452961 1.969527731 0.931347088 0.324340516 -0.114453286 0.197195454 FBgn0035401 Alg2 - http://flybase.org/reports/FBgn0035401 protein_coding_gene "alpha-1,3-mannosyltransferase activity ; GO:0000033 | inferred from biological aspect of ancestor with PANTHER:PTN000282458" oligosaccharide-lipid intermediate biosynthetic process ; GO:0006490 | inferred from biological aspect of ancestor with PANTHER:PTN001394375 protein glycosylation in endoplasmic reticulum ; GO:0033577 | inferred from biological aspect of ancestor with PANTHER:PTN001394375 endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN001394375 lipid particle ; GO:0005811 | inferred from direct assay endomembrane system ; GO:0012505 | inferred from direct assay "CG1291, Alg2, dAlg2" "IPR001296:Glycosyl transferase, family 1, IPR028098:Glycosyltransferase subfamily 4-like, N-terminal domain" CG1291 27-Aug-18 DroID_v2018_08 Drer\alg2 Scer\ALG2 "Cele\algn-2, Cele\bus-8" Xtro\alg2 Mmus\Alg2 Hsap\ALG2 "lethal,lethal - all die before end of pupal stage,some die during pupal stage" embryonic/larval brain FBgn0034693 CG11073 - http://flybase.org/reports/FBgn0034693 protein_coding_gene - - - CG11073 - CG11073 27-Aug-18 DroID_v2018_08 - - - Xtro\map4 - - "viable,fertile" DRSC04087 K 0.032397861 0.606218717 0.834528238 0.087522026 0.469254622 1.876953573 FBgn0002242 l(3)68Cd lethal (3) 68Cd http://flybase.org/reports/FBgn0002242 - gene - - - "rsg3, l(3)rsg3, l(3)Bl[D], l(3)68Cd" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0032445 CG6153 - http://flybase.org/reports/FBgn0032445 protein_coding_gene - cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000256298 "CG6153, 6153" "IPR010400:PITH domain, IPR008979:Galactose-binding domain-like" CG6153 27-Aug-18 DroID_v2018_08 Drer\pithd1 - Cele\ZK353.9 Xtro\pithd1 Mmus\Pithd1 Hsap\PITHD1 viable FBgn0012011 tRNA:Val-AAC-1-1 transfer RNA:Valine-AAC 1-1 http://flybase.org/reports/FBgn0012011 "FBgn0012007, FBgn0051587, FBgn0060030" tRNA_gene GUU codon-amino acid adaptor activity ; GO:0033449 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033449 cytosol ; GO:0005829 | inferred by curator from GO:0033449 "valine tRNA, tRNA-Val-4, val-tRNA-4, tRNA[Val][[4]], AE002708.trna7-ValAAC, tRNA:V4, tRNA:V:AAC:AE002708-a, CR31587, tRNA:val4:89BC, tRNA[Val-AAC], chr3R.trna13-ValAAC, tRNA:Val-AAC-1-1, tRNA:V4:89BC, tRNA-Val-AAC-1-1, GUU" - CR31587 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004367 mei-41 meiotic 41 http://flybase.org/reports/FBgn0004367 "FBgn0002708, FBgn0002880" protein_coding_gene protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with HGNC:882 protein kinase activity ; GO:0004672 | non-traceable author statement "response to radiation ; GO:0009314 | traceable author statement imaginal disc development ; GO:0007444 | traceable author statement peptidyl-serine phosphorylation ; GO:0018105 | inferred from sequence or structural similarity with HGNC:882 regulation of mitotic nuclear division ; GO:0007088 | inferred from mutant phenotype inferred from genetic interaction with dup cellularization ; GO:0007349 | traceable author statement double-strand break repair via synthesis-dependent strand annealing ; GO:0045003 | inferred from mutant phenotype reciprocal meiotic recombination ; GO:0007131 | inferred from mutant phenotype female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype DNA damage checkpoint ; GO:0000077 | inferred from mutant phenotype response to caffeine ; GO:0031000 | inferred from genetic interaction with MAGE actin filament organization ; GO:0007015 | inferred from mutant phenotype phosphorylation ; GO:0016310 | non-traceable author statement regulation of cell shape ; GO:0008360 | inferred from mutant phenotype telomere maintenance ; GO:0000723 | inferred from genetic interaction with tefu, nbs mitotic DNA replication checkpoint ; GO:0033314 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from mutant phenotype inferred from genetic interaction with nbs DNA damage checkpoint ; GO:0000077 | traceable author statement DNA replication checkpoint ; GO:0000076 | inferred from mutant phenotype double-strand break repair via single-strand annealing ; GO:0045002 | inferred from mutant phenotype oogenesis ; GO:0048477 | traceable author statement oocyte fate determination ; GO:0030716 | inferred from mutant phenotype regulation of syncytial blastoderm mitotic cell cycle ; GO:0007348 | traceable author statement meiotic nuclear division ; GO:0007126 | traceable author statement mitotic cell cycle checkpoint ; GO:0007093 | traceable author statement meiotic DNA double-strand break processing ; GO:0000706 | inferred from direct assay cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype embryonic development via the syncytial blastoderm ; GO:0001700 | traceable author statement chromosome condensation ; GO:0030261 | inferred from genetic interaction with PR-Set7 protein phosphorylation ; GO:0006468 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:882 "mei-41, ATR, CG4252, meiP41, mus104, mei41, mus103, MEI41/FRP1, Mei-41, MEI41, mus-104, mus(1)104, fs(1)M37, mus(1)103, mus-103, atr, mei-195, DmATR, Mei-41/DATR, 4252, Dmmei41" "IPR018936:Phosphatidylinositol 3/4-kinase, conserved site, IPR000403:Phosphatidylinositol 3-/4-kinase, catalytic domain, IPR003151:PIK-related kinase, FAT, IPR003152:FATC domain, IPR011009:Protein kinase-like domain, IPR012993:UME domain, IPR014009:PIK-related kinase, IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical, IPR011990:Tetratricopeptide-like helical domain" CG4252 27-Aug-18 DroID_v2018_08 Drer\atr "Scer\MEC1, Scer\TEL1" "Cele\atl-1, Cele\smg-1, Cele\atm-1" Xtro\atr Mmus\Atr Hsap\ATR oogenesis stage && adult stage | female ovary

"female sterile,partially,chemical sensitive,viable,semidominant,heat sensitive,recessive,radiation sensitive,lethal - all die before end of embryonic stage,some die during embryonic stage,meiotic cell cycle defective,female fertile,wild-type,lethal,rescuable maternal effect,female semi-sterile,maternal effect,DNA repair defective,dominant,mitotic cell cycle defective,radiation resistant,reduced,decreased cell death,increased cell death" "egg,maternal effect,mitotic interphase | embryonic cycle 12 | maternal effect,mitotic interphase | embryonic cycle 13 | maternal effect,blastoderm embryo,cycle 13 embryo,cycle 14 embryo,spindle,neuroblast,presumptive oocyte,mitosis & nuclear chromosome,eye disc,conditional,morphogenetic furrow,metaphase & condensed nuclear chromosome | conditional qualifier,wing disc,SO0000340chromosome | larval stage" FBgn0065102 snmRNA:184 small non-messenger RNA 184 http://flybase.org/reports/FBgn0065102 non_protein_coding_gene - - - "Dm-184, CR33916, snmRNA:184" - CR33916 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0011007 l(3)s1696 lethal (3) s1696 http://flybase.org/reports/FBgn0011007 - gene - - - l(3)s1696 - - 27-Aug-18 DroID_v2018_08 - - - - - - partially lethal - majority die FBgn0037723 SpdS Spermidine Synthase http://flybase.org/reports/FBgn0037723 protein_coding_gene spermidine synthase activity ; GO:0004766 | inferred from biological aspect of ancestor with PANTHER:PTN000900703 spermidine biosynthetic process ; GO:0008295 | inferred from biological aspect of ancestor with PANTHER:PTN000900703 cellular_component ; GO:0005575 | no biological data available "CG8327, SpdS, Spds" "IPR030373:Polyamine biosynthesis domain, conserved site, IPR030374:Polyamine biosynthesis domain, IPR001045:Spermidine/spermine synthases, IPR030668:Spermidine/spermine synthase, eukaryotes, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG8327 27-Aug-18 DroID_v2018_08 "Drer\srm, Drer\sms" "Scer\SPE4, Scer\SPE3" Cele\spds-1 "Xtro\sms, Xtro\srm" "Mmus\Sms, Mmus\Srm" "Hsap\SMS, Hsap\SRM" "long lived,viable" FBgn0058412 CG40412 - http://flybase.org/reports/FBgn0058412 protein_coding_gene - - - CG40412 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0082981 snoRNA:Psi28S-2949 snoRNA:Psi28S-2949 http://flybase.org/reports/FBgn0082981 snoRNA_gene - - - "snoRNA:Psi28S-2949, psi28S-2949, Psi 28S-2949, CR34525, Psi28S-2949" - CR34525 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032648 CG15144 - http://flybase.org/reports/FBgn0032648 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15144 "IPR032840:MAATS1 domain, IPR026720:Protein MAATS1" CG15144 27-Aug-18 DroID_v2018_08 Drer\maats1 - - Xtro\maats1 Mmus\Maats1 Hsap\MAATS1 viable FBgn0267257 lncRNA:CR45693 - http://flybase.org/reports/FBgn0267257 non_protein_coding_gene - - - CR45693 - CR45693 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259388 C545 - http://flybase.org/reports/FBgn0259388 gene - - - C545 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing,wing vein" FBgn0082914 wst wasted http://flybase.org/reports/FBgn0082914 gene - sperm storage ; GO:0046693 | inferred from mutant phenotype sperm entry ; GO:0035037 | inferred from mutant phenotype sperm chromatin decondensation ; GO:0035041 | inferred from mutant phenotype - "wst, wasted" - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,female fertile,male sterile,recessive" male pronucleus FBgn0070022 BG00829 BG00829 http://flybase.org/reports/FBgn0070022 gene - - - BG00829 - - 27-Aug-18 DroID_v2018_08 - - - - - - stress response defective FBgn0037433 CG17919 - http://flybase.org/reports/FBgn0037433 protein_coding_gene anion binding ; GO:0043168 | inferred from sequence or structural similarity with HGNC:8630 response to bacterium ; GO:0009617 | inferred from expression pattern multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay CG17919 "IPR001858:Phosphatidylethanolamine-binding, conserved site, IPR008914:Phosphatidylethanolamine-binding protein" CG17919 27-Aug-18 DroID_v2018_08 "Drer\mrpl38, Drer\pebp1, Drer\pebp4" "Scer\MRPL35, Scer\TFS1, Scer\YLR179C" "Cele\F40A3.3, Cele\Y69E1A.5" "Xtro\pebp4, Xtro\pebp1, Xtro\mrpl38" "Mmus\Pebp1, Mmus\Pebp4, Mmus\Mrpl38, Mmus\Pbp2" "Hsap\PEBP1, Hsap\MRPL38, Hsap\PEBP4" "viable,fertile" DRSC27860 K 0.52523435 -0.239638519 0.773168894 0.257416664 1.889964946 3.35145055 FBgn0031407 CG4270 - http://flybase.org/reports/FBgn0031407 protein_coding_gene - - extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR018244 "BcDNA:AT04879, CG4270" "IPR018244:Allergen V5/Tpx-1-related, conserved site, IPR001283:Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR002413:Ves allergen, IPR014044:CAP domain, IPR034113:Golgi-associated plant pathogenesis-related protein 1, SCP domain" CG4270 27-Aug-18 DroID_v2018_08 "Drer\r3hdml, Drer\pi15b, Drer\pi15a, Drer\LOC100536500, Drer\glipr1b, Drer\glipr2, Drer\crispld2, Drer\crispld1b, Drer\glipr2l, Drer\im:7150988, Drer\crispld1a" "Scer\CDC25, Scer\PRY2, Scer\PRY1, Scer\PRY3" "Cele\D2062.1, Cele\F09B9.5, Cele\C07A4.2, Cele\F57B7.2, Cele\W05B10.4, Cele\scl-19, Cele\C07A4.3, Cele\scl-1" "Xtro\crispld2, Xtro\crisp1, Xtro\r3hdml, Xtro\MGC108118, Xtro\glipr2, Xtro\crisp3, Xtro\crisp2" "Mmus\Ralgds, Mmus\Crisp2, Mmus\Pi15, Mmus\Crisp1, Mmus\Pi16, Mmus\Crispld1, Mmus\Crisp4, Mmus\R3hdml, Mmus\Clec18a, Mmus\Crisp3, Mmus\Glipr1l1, Mmus\Glipr2, Mmus\Glipr1l2, Mmus\Glipr1, Mmus\Crispld2" "Hsap\CLEC18C, Hsap\CRISP1, Hsap\GLIPR1L1, Hsap\CLEC18B, Hsap\RGL4, Hsap\GLIPR2, Hsap\CRISPLD2, Hsap\RALGDS, Hsap\PI16, Hsap\R3HDML, Hsap\PI15, Hsap\CRISPLD1, Hsap\GLIPR1, Hsap\CLEC18A, Hsap\GLIPR1L2, Hsap\CRISP2" "viable,visible" mesothoracic tergum DRSC00648 K 1.13659701 -0.209719651 0.358052422 -0.053894389 0.467995676 1.568416809 FBgn0020826 l(3)03647 lethal (3) 03647 http://flybase.org/reports/FBgn0020826 - gene - - - l(3)03647 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051115 CG31115 - http://flybase.org/reports/FBgn0051115 protein_coding_gene S-methyl-5-thioadenosine phosphorylase activity ; GO:0017061 | inferred from electronic annotation with InterPro:IPR010044 nucleoside metabolic process ; GO:0009116 | inferred from electronic annotation with InterPro:IPR000845 - CG31115 "IPR000845:Nucleoside phosphorylase domain, IPR010044:Methylthioadenosine phosphorylase (MTAP)" CG31115 27-Aug-18 DroID_v2018_08 Drer\mtap Scer\MEU1 Cele\B0228.7 Xtro\mtap Mmus\Mtap Hsap\MTAP viable FBgn0265267 CG18258 - http://flybase.org/reports/FBgn0265267 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from electronic annotation with InterPro:IPR000734 molecular_function ; GO:0003674 | no biological data available lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR033906 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CT41369, CG18258, anon-SAGE:Wang-051" "IPR033906:Lipase, N-terminal, IPR029058:Alpha/Beta hydrolase fold, IPR000734:Triacylglycerol lipase family, IPR013818:Lipase/vitellogenin" CG18258 27-Aug-18 DroID_v2018_08 "Drer\lipca, Drer\lipib, Drer\lipg, Drer\pla1a, Drer\lipia, Drer\lpl, Drer\LOC101884800, Drer\LOC100331214" - - "Xtro\lipg, Xtro\lpl" "Mmus\Pnlip, Mmus\Lipi, Mmus\Lipg, Mmus\Liph, Mmus\Pnliprp1, Mmus\Lipc, Mmus\Pnliprp2, Mmus\Lpl, Mmus\Pla1a" "Hsap\LIPH, Hsap\LIPG, Hsap\PLA1A, Hsap\PNLIPRP2, Hsap\LIPI, Hsap\LIPC, Hsap\LPL, Hsap\PNLIPRP1, Hsap\PNLIPRP3, Hsap\PNLIP" FBgn0002069 AspRS Aspartyl-tRNA synthetase http://flybase.org/reports/FBgn0002069 "FBgn0022204, FBgn0025948" protein_coding_gene "aspartate-tRNA ligase activity ; GO:0004815 | inferred from electronic annotation with InterPro:IPR004523 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002312, InterPro:IPR004364, InterPro:IPR004523, InterPro:IPR018150 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR004365 aspartate-tRNA ligase activity ; GO:0004815 | traceable author statement" aspartyl-tRNA aminoacylation ; GO:0006422 | inferred from electronic annotation with InterPro:IPR004523 aspartyl-tRNA aminoacylation ; GO:0006422 | traceable author statement growth ; GO:0040007 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR004523 cytoplasm ; GO:0005737 | traceable author statement aminoacyl-tRNA synthetase multienzyme complex ; GO:0017101 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay "CG3821, aats-asp, poney, l(2)49Db, l(2)k04508, AspRS, DRS, cDNA1, vr1, l(2)vr1, clone 2.49, anon-EST:Liang-2.49, l(2)v27, Aats-Asp, Aats-asp" "IPR002312:Aspartyl/Asparaginyl-tRNA synthetase, class IIb, IPR004364:Aminoacyl-tRNA synthetase, class II (D/K/N), IPR004365:OB-fold nucleic acid binding domain, AA-tRNA synthetase-type, IPR004523:Aspartate-tRNA synthetase, type 2, IPR006195:Aminoacyl-tRNA synthetase, class II, IPR012340:Nucleic acid-binding, OB-fold" CG3821 27-Aug-18 DroID_v2018_08 Drer\dars Scer\DPS1 Cele\dars-1 Xtro\dars Mmus\Dars Hsap\DARS embryonic stage "

ubiquitous , embryonic/larval salivary gland

" "lethal,recessive,mitotic cell cycle defective,lethal - all die before end of larval stage,some die during larval stage,cell autonomous,decreased cell size,somatic clone,wild-type,non-suppressor of variegation,dominant,lethal - all die before end of pupal stage,some die during pupal stage,neuroanatomy defective" "wing disc,cell autonomous,somatic clone,wing,embryonic/larval neuroblast,ganglion mother cell" FBgn0051051 CG31051 - http://flybase.org/reports/FBgn0051051 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CT3186, CG1540, CG31051" - CG31051 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC15034 E -0.112870161 0.915641129 0.359011628 1.623710019 0.425581888 0.435726266 FBgn0086057 snoRNA:Me28S-G2017 - http://flybase.org/reports/FBgn0086057 snoRNA_gene - - - "snoRNA:Me28S-G2017, Me28S-Gm2017, Me28S-C2017, CR34686" - CR34686 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259474 EP-738 - http://flybase.org/reports/FBgn0259474 gene - - - EP-738 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible wing vein L3 FBgn0263950 BG00817 - http://flybase.org/reports/FBgn0263950 gene - - - BG00817 - - 27-Aug-18 DroID_v2018_08 - - - - - - "long lived,male limited,starvation stress response defective,temperature response defective,female limited,gravitaxis defective" FBgn0026778 Rad1 Radiation insensitive 1 http://flybase.org/reports/FBgn0026778 - protein_coding_gene 3'-5' exonuclease activity ; GO:0008408 | inferred from biological aspect of ancestor with PANTHER:PTN000853143 damaged DNA binding ; GO:0003684 | inferred from biological aspect of ancestor with PANTHER:PTN000093171 DNA repair ; GO:0006281 | inferred from biological aspect of ancestor with PANTHER:PTN000093171 DNA damage checkpoint ; GO:0000077 | inferred from biological aspect of ancestor with PANTHER:PTN000093171 checkpoint clamp complex ; GO:0030896 | inferred from direct assay "Rad1[Dm], CG3240, Rad1, Dromel_CG3240_FBtr0077747_rad1_mORF, rad1, DmRad1" "IPR003011:Cell cycle checkpoint protein, Rad1, IPR003021:Rad1/Rec1/Rad17" CG3240 27-Aug-18 DroID_v2018_08 Drer\rad1 Scer\RAD17 Cele\mrt-2 Xtro\rad1 Mmus\Rad1 Hsap\RAD1 "viable,fertile" FBgn0001720 l(1)ESHS41 lethal (1) ESHS41 http://flybase.org/reports/FBgn0001720 - gene - - - l(1)ESHS41 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0086301 mace mace http://flybase.org/reports/FBgn0086301 gene - filopodium assembly ; GO:0046847 | inferred from mutant phenotype - mace - - 27-Aug-18 DroID_v2018_08 - - - - - - "neuroanatomy defective,lethal,recessive" "dendrite | larval stage,dorsal multidendritic neuron ddaA & filopodium" FBgn0085195 CG34166 - http://flybase.org/reports/FBgn0085195 protein_coding_gene - - - "CG34166, CG15281" - CG34166 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0028195 l(3)S022348 lethal (3) S022348 http://flybase.org/reports/FBgn0028195 gene - - - "0223/48, l(3)S022348" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0035375 Pgant6 polypeptide GalNAc transferase 6 http://flybase.org/reports/FBgn0035375 protein_coding_gene polypeptide N-acetylgalactosaminyltransferase activity ; GO:0004653 | inferred from direct assay oligosaccharide biosynthetic process ; GO:0009312 | inferred from direct assay Golgi stack ; GO:0005795 | non-traceable author statement endoplasmic reticulum ; GO:0005783 | inferred from direct assay "CG2103, pgant6, Pgant6" "IPR000772:Ricin B, lectin domain, IPR001173:Glycosyltransferase 2-like, IPR029044:Nucleotide-diphospho-sugar transferases" CG2103 27-Aug-18 DroID_v2018_08 "Drer\galnt10, Drer\galnt16, Drer\LOC101882942, Drer\galnt6, Drer\galnt12, Drer\LOC100535692, Drer\LOC568645, Drer\galnt2, Drer\galnt9, Drer\galnt18b, Drer\wbscr17, Drer\poc1bl, Drer\LOC103910015, Drer\galnt1, Drer\galnt8b, Drer\si:ch211-15e22.3, Drer\LOC101886587, Drer\galnt3, Drer\galnt7, Drer\LOC100334784, Drer\galnt13, Drer\galnt14, Drer\galnt8a.1, Drer\galnt11" - "Cele\gly-11, Cele\gly-10, Cele\gly-7, Cele\gly-9, Cele\gly-3" "Xtro\wbscr17, Xtro\galnt2, Xtro\galnt15, Xtro\galnt9, Xtro\galnt4, Xtro\galnt16, Xtro\galnt1, Xtro\galnt7, Xtro\galnt13, Xtro\galnt14, Xtro\galnt10, Xtro\galnt6.1, Xtro\galnt12" "Mmus\Galnt3, Mmus\Galnt12, Mmus\Galnt13, Mmus\Galnt15, Mmus\Galnt16, Mmus\Galntl5, Mmus\Galntl6, Mmus\Galnt5, Mmus\Wbscr17, Mmus\Galnt7, Mmus\Galnt18, Mmus\Galnt14, Mmus\Galnt11, Mmus\Galnt4, Mmus\Galnt1, Mmus\Galnt9, Mmus\Galnt6, Mmus\Galnt2, Mmus\Galnt10" "Hsap\GALNT7, Hsap\GALNT18, Hsap\GALNTL5, Hsap\GALNT16, Hsap\GALNT5, Hsap\GALNT14, Hsap\GALNT6, Hsap\GALNT10, Hsap\GALNT11, Hsap\GALNTL6, Hsap\GALNT9, Hsap\GALNT4, Hsap\GALNT1, Hsap\GALNT3, Hsap\GALNT8, Hsap\GALNT15, Hsap\GALNT12, Hsap\GALNT2, Hsap\POC1B-GALNT4, Hsap\GALNT13, Hsap\WBSCR17" "viable,fertile,partially lethal - majority die" DRSC26927 K -0.127862827 -0.704383345 1.214036843 0.174381164 -0.643245135 1.533963867 FBgn0067758 l(1)G0029 lethal (1) G0029 http://flybase.org/reports/FBgn0067758 gene - - - l(1)G0029 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of P-stage,some die during pharate adult stage" FBgn0027655 htt huntingtin http://flybase.org/reports/FBgn0027655 - protein_coding_gene - axo-dendritic transport ; GO:0008088 | inferred from mutant phenotype neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype establishment of mitotic spindle orientation ; GO:0000132 | inferred from mutant phenotype synaptic vesicle transport ; GO:0048489 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay "CG9995, dhtt, HD, Htt, htt, HTT, dHtt, DmHtt" "IPR016024:Armadillo-type fold, IPR024613:Huntingtin, middle-repeat, IPR028426:Huntingtin family, IPR011989:Armadillo-like helical" CG9995 27-Aug-18 DroID_v2018_08 Drer\htt - Cele\F21G4.6 Xtro\htt Mmus\Htt Hsap\HTT "viable,fertile,short lived,visible,progressive,neuroanatomy defective,sleep defective" "axon | larval stageAppl.G1a,embryonic/larval brain,eye,ommatidium,progressive" FBgn0019872 l(3)96Ab lethal (3) 96Ab http://flybase.org/reports/FBgn0019872 - gene - - - "299.1, anon-96Ab, l(3)96Ab" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0264268 lncRNA:CR43768 - http://flybase.org/reports/FBgn0264268 non_protein_coding_gene - - - CR43768 - CR43768 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265529 lncRNA:CR44379 - http://flybase.org/reports/FBgn0265529 non_protein_coding_gene - - - "CR44379, lincRNA.327" - CR44379 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266650 lncRNA:CR45157 - http://flybase.org/reports/FBgn0266650 non_protein_coding_gene - - - CR45157 - CR45157 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0086025 snoRNA:Me28S-A2589c - http://flybase.org/reports/FBgn0086025 snoRNA_gene - - - "snoRNA:Me28S-A2589c, Me28S-Am2589c, CR34654, chr2R:16839179..16839292" - CR34654 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0003229 ref(1)H refractory to sigma H http://flybase.org/reports/FBgn0003229 - gene - - - "Ref(1)H, ref(1)H" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000951 Fs(2)Bil Female sterile (2) Billa http://flybase.org/reports/FBgn0000951 - gene - - - "Billa, Fs(2)Sz2, Fs(2)Bil" - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile germline-dependent,dominant" "dorsal appendage,egg" FBgn0029759 CG12732 - http://flybase.org/reports/FBgn0029759 protein_coding_gene - - - CG12732 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267127 lncRNA:CR45567 - http://flybase.org/reports/FBgn0267127 non_protein_coding_gene - - - CR45567 - CR45567 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0261514 NimA Nimrod A http://flybase.org/reports/FBgn0261514 protein_coding_gene molecular_function ; GO:0003674 | no biological data available phagocytosis ; GO:0006909 | inferred from sequence or structural similarity with drpr negative regulation of Notch signaling pathway ; GO:0045746 | inferred from biological aspect of ancestor with PANTHER:PTN001170207 integral component of membrane ; GO:0016021 | inferred from sequence model "CG31765, j, CT25428, CG8855, BG:DS00180.5, DS00180.5, CG31841, CG42282, NimA, nimA" "IPR000742:EGF-like domain, IPR013032:EGF-like, conserved site, IPR011489:EMI domain" CG42282 27-Aug-18 DroID_v2018_08 "Drer\megf11, Drer\dkk1a, Drer\megf6a, Drer\dkk2, Drer\scarf1, Drer\zgc:158328, Drer\pear1, Drer\LOC101883341, Drer\megf10, Drer\esm1, Drer\tnfaip6, Drer\ccbe1, Drer\megf6b" - Cele\Y64G10A.7 "Xtro\tnfaip6, Xtro\megf11, Xtro\stab2" "Mmus\Tnfaip6, Mmus\Esm1, Mmus\Pear1, Mmus\Stab1, Mmus\Scarf1, Mmus\Dkk2, Mmus\Megf11, Mmus\Megf10, Mmus\Egfem1, Mmus\Megf6, Mmus\Dkk3, Mmus\Dlk1" "Hsap\SCARF2, Hsap\DKK2, Hsap\PEAR1, Hsap\MEGF6, Hsap\TIE1, Hsap\MEGF11, Hsap\DLK1, Hsap\SCARF1, Hsap\TNFAIP6, Hsap\MEGF10" FBgn0063499 GstE10 Glutathione S transferase E10 http://flybase.org/reports/FBgn0063499 protein_coding_gene glutathione transferase activity ; GO:0004364 | inferred from direct assay glutathione metabolic process ; GO:0006749 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with RGD:70952 "CG17522, DmGSTE10, GstE10, GSTE10, gste10" "IPR004045:Glutathione S-transferase, N-terminal, IPR004046:Glutathione S-transferase, C-terminal, IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold" CG17522 27-Aug-18 DroID_v2018_08 "Drer\gstt1b, Drer\gstt1a, Drer\mars, Drer\eef1e1, Drer\gstr, Drer\eef1g, Drer\gstt2, Drer\vars" "Scer\CAM1, Scer\YGR201C, Scer\GTT2, Scer\URE2, Scer\TEF4, Scer\GTT1" "Cele\gst-21, Cele\gst-29" "Xtro\gstt1, Xtro\eef1g, Xtro\eef1e1" "Mmus\Gstt4, Mmus\Eef1e1, Mmus\Eef1g, Mmus\Gstt3, Mmus\Mars, Mmus\Gstt2, Mmus\Vars, Mmus\Gstt1" "Hsap\EEF1E1, Hsap\GSTT1, Hsap\GSTT2, Hsap\EEF1G, Hsap\MARS, Hsap\GSTT2B, Hsap\VARS" viable FBgn0039004 Nup133 Nucleoporin 133kD http://flybase.org/reports/FBgn0039004 protein_coding_gene nucleocytoplasmic transporter activity ; GO:0005487 | inferred from sequence or structural similarity with HGNC:18016 nucleocytoplasmic transporter activity ; GO:0005487 | inferred from biological aspect of ancestor with PANTHER:PTN000334066 structural constituent of nuclear pore ; GO:0017056 | inferred from biological aspect of ancestor with PANTHER:PTN000334066 "chromatin organization ; GO:0006325 | inferred from biological aspect of ancestor with PANTHER:PTN000334066 SMAD protein import into nucleus ; GO:0007184 | NOT inferred from mutant phenotype nuclear pore distribution ; GO:0031081 | inferred from biological aspect of ancestor with PANTHER:PTN000334066 regulation of transcription, DNA-templated ; GO:0006355 | inferred from biological aspect of ancestor with PANTHER:PTN000334066 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery ; GO:0000972 | inferred from biological aspect of ancestor with PANTHER:PTN000334066 protein import into nucleus ; GO:0006606 | inferred from biological aspect of ancestor with PANTHER:PTN000334066 RNA export from nucleus ; GO:0006405 | inferred from biological aspect of ancestor with PANTHER:PTN000334066 mRNA export from nucleus ; GO:0006406 | inferred from sequence or structural similarity with HGNC:18016" condensed chromosome kinetochore ; GO:0000777 | colocalizes_with inferred from biological aspect of ancestor with PANTHER:PTN000334066 nuclear pore outer ring ; GO:0031080 | inferred from sequence or structural similarity with HGNC:18016 nuclear pore outer ring ; GO:0031080 | inferred from biological aspect of ancestor with PANTHER:PTN000334066 "Nup133, CG6958, nup133, Nup 133" "IPR007187:Nucleoporin, Nup133/Nup155-like, C-terminal, IPR015943:WD40/YVTN repeat-like-containing domain, IPR014908:Nucleoporin, Nup133/Nup155-like, N-terminal" CG6958 27-Aug-18 DroID_v2018_08 Drer\nup133 Scer\NUP133 Cele\npp-15 Xtro\nup133 Mmus\Nup133 Hsap\NUP133 FBgn0082619 S(CycE[JP])59S18 S(CycE[JP])59S18 http://flybase.org/reports/FBgn0082619 gene - - - "59S18, S(CycE[JP])59S18" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0263109 CG43366 - http://flybase.org/reports/FBgn0263109 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | NOT inferred from key residues biological_process ; GO:0008150 | no biological data available extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000156122 "CG43366, CG12551, CG14470" "IPR000215:Serpin family, IPR023795:Serpin, conserved site, IPR023796:Serpin domain" CG43366 27-Aug-18 DroID_v2018_08 "Drer\zgc:174260, Drer\serpina7, Drer\si:ch211-186e20.7, Drer\zgc:174259, Drer\serpina1, Drer\serpina1l" - - - "Mmus\Serpina3j, Mmus\Serpina3k, Mmus\Serpina3i, Mmus\Serpina3b, Mmus\Serpina11, Mmus\Serpina9, Mmus\Serpina1e, Mmus\Serpina6, Mmus\Serpina1a, Mmus\Serpina3a, Mmus\Serpina1c, Mmus\Serpina1d, Mmus\Serpina3c, Mmus\Serpina16, Mmus\Serpina5, Mmus\Serpina3f, Mmus\Serpina7, Mmus\Serpina3n, Mmus\Serpina3g, Mmus\Serpina12, Mmus\Serpina3m, Mmus\Serpina1f, Mmus\Serpina1b" "Hsap\SERPINA5, Hsap\SERPINA2, Hsap\SERPINA9, Hsap\SERPINA7, Hsap\SERPINA11, Hsap\SERPINA3, Hsap\SERPINA1, Hsap\SERPINA4, Hsap\SERPINA12, Hsap\SERPINA6" DRSC25725 K -0.397217175 0.111318732 0.936519971 0.637256728 1.893891475 -0.476813472 FBgn0259360 EP-614 - http://flybase.org/reports/FBgn0259360 gene - - - EP-614 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible wing FBgn0004507 GlyP Glycogen phosphorylase http://flybase.org/reports/FBgn0004507 "FBgn0027859, FBgn0063790" protein_coding_gene glycogen phosphorylase activity ; GO:0008184 | inferred from direct assay protein homodimerization activity ; GO:0042803 | inferred from direct assay glycogen phosphorylase activity ; GO:0008184 | inferred from mutant phenotype pyridoxal phosphate binding ; GO:0030170 | inferred from direct assay negative regulation of innate immune response ; GO:0045824 | inferred from mutant phenotype flight ; GO:0060361 | inferred from mutant phenotype positive regulation of glycogen catabolic process ; GO:0045819 | inferred from mutant phenotype glycogen catabolic process ; GO:0005980 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype protein complex ; GO:0043234 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000157685 "GlyP, GP, l(2)k07918, Glp1, DGPH, CG7254, BcDNA:LD24485, anon-WO0257455.33, Glyp" "IPR000811:Glycosyl transferase, family 35, IPR011833:Glycogen/starch/alpha-glucan phosphorylase" CG7254 27-Aug-18 DroID_v2018_08 "Drer\pygma, Drer\pygb, Drer\pygl, Drer\pygmb" Scer\GPH1 Cele\T22F3.3 "Xtro\pygl, Xtro\pygm" "Mmus\Pygb, Mmus\Pygm, Mmus\Pygl" "Hsap\PYGM, Hsap\PYGB, Hsap\PYGL" " embryonic stage | 0-2hr , embryonic stage -- adult stage " "long lived,RU486 conditional,viable,reduced" FBgn0060824 l(3)S051701b lethal (3) S051701b http://flybase.org/reports/FBgn0060824 gene - - - "0517/01, l(3)S051701b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0004411 het-rep3 heterochromatic repeat 3 http://flybase.org/reports/FBgn0004411 - repeat_region - - - het-rep3 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051296 CG31296 - http://flybase.org/reports/FBgn0051296 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available extracellular region ; GO:0005576 | inferred from sequence model "NEST:bs01d08, CG31296" "IPR001283:Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR014044:CAP domain, IPR034763:Venom allergen 3, insect" CG31296 27-Aug-18 DroID_v2018_08 "Drer\crispld1a, Drer\pi15a, Drer\r3hdml, Drer\glipr2l, Drer\glipr1b, Drer\crispld1b, Drer\glipr2, Drer\crispld2, Drer\LOC100536500, Drer\pi15b" "Scer\PRY1, Scer\PRY3, Scer\PRY2" "Cele\scl-10, Cele\scl-15, Cele\scl-19, Cele\vap-2, Cele\scl-5, Cele\scl-17, Cele\scl-23, Cele\scl-13, Cele\scl-18, Cele\scl-14, Cele\scl-20, Cele\scl-7, Cele\scl-3, Cele\scl-12, Cele\scl-11, Cele\scl-8, Cele\scl-6, Cele\scl-9, Cele\scl-21, Cele\scl-2, Cele\scl-1" "Xtro\crisp2, Xtro\glipr2, Xtro\crispld2, Xtro\MGC108118, Xtro\crisp3, Xtro\crisp1, Xtro\r3hdml" "Mmus\Crisp1, Mmus\Glipr1, Mmus\Crisp3, Mmus\Clec18a, Mmus\Glipr2, Mmus\Crisp2, Mmus\Pi15, Mmus\Glipr1l1, Mmus\Crispld2, Mmus\Crispld1, Mmus\R3hdml, Mmus\Glipr1l2, Mmus\Crisp4, Mmus\Pi16" "Hsap\CRISP1, Hsap\CRISPLD1, Hsap\CLEC18B, Hsap\CLEC18C, Hsap\PI16, Hsap\GLIPR1L2, Hsap\GLIPR1, Hsap\GLIPR2, Hsap\CRISP2, Hsap\GLIPR1L1, Hsap\CRISPLD2, Hsap\PI15, Hsap\CLEC18A, Hsap\R3HDML" viable FBgn0004061 bip bipolar oocyte http://flybase.org/reports/FBgn0004061 - gene molecular_function ; GO:0003674 | no biological data available oocyte anterior/posterior axis specification ; GO:0007314 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "bip, BiP" - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive" "dorsal appendage,egg chamber,nurse cell,stage S14B oocyte,oocyte" FBgn0002555 lm limited http://flybase.org/reports/FBgn0002555 - gene - - - lm - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,female sterile" "sternite,macrochaeta" FBgn0022963 splinter splinter http://flybase.org/reports/FBgn0022963 - gene - - - splinter - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065354 l(2)SH1775 lethal (2) SH1775 http://flybase.org/reports/FBgn0065354 gene - - - "l(2)SH1775, l(2)SH2 1775" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0033501 CG12911 - http://flybase.org/reports/FBgn0033501 protein_coding_gene - - - CG12911 - CG12911 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" FBgn0037261 CG9775 - http://flybase.org/reports/FBgn0037261 protein_coding_gene - - - CG9775 "IPR025715:Chromatin target of PRMT1 protein, C-terminal" CG9775 27-Aug-18 DroID_v2018_08 Drer\chtopa - - Xtro\chtop Mmus\Chtop Hsap\CHTOP viable DRSC22667 IE 2.748252541 -0.516737251 3.175856949 2.073436003 0.028200923 -0.726305087 FBgn0052023 CG32023 - http://flybase.org/reports/FBgn0052023 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32023 - CG32023 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0025506 l(3)72Fa lethal (3) 72Fa http://flybase.org/reports/FBgn0025506 - gene - - - l(3)72Fa - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of first instar larval stage,some die during first instar larval stage" FBgn0065716 l(2)SH0578 lethal (2) SH0578 http://flybase.org/reports/FBgn0065716 gene - - - "l(2)SH0578, l(2)SH2 0578" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0005048 exr extra venation http://flybase.org/reports/FBgn0005048 - gene - - - exr - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,female sterile,recessive,male fertile,visible" "eye,wing vein,wing" FBgn0024628 l(2)k15306 lethal (2) k15306 http://flybase.org/reports/FBgn0024628 - gene - - - "153/6, l(2)k15306" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" imaginal disc FBgn0267801 lncRNA:CR46126 - http://flybase.org/reports/FBgn0267801 non_protein_coding_gene - - - CR46126 - CR46126 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0013624 l(3)neo15 lethal (3) neo15 http://flybase.org/reports/FBgn0013624 - gene - - - l(3)neo15 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" imaginal disc FBgn0034824 Klp59C Kinesin-like protein at 59C http://flybase.org/reports/FBgn0034824 protein_coding_gene "microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR001752 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001752, InterPro:IPR019821 motor activity ; GO:0003774 | inferred from direct assay microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity ATPase activity ; GO:0016887 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 microtubule motor activity ; GO:0003777 | inferred from biological aspect of ancestor with PANTHER:PTN000648413" microtubule-based movement ; GO:0007018 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity kinesin complex ; GO:0005871 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 kinetochore microtubule ; GO:0005828 | inferred from direct assay kinesin complex ; GO:0005871 | inferred from sequence or structural similarity "KLP59C, DmKLP59C, CG3219, DmKlp59C, DmCG3219, Klp59C, KIF 2B, KIF2A/B/C" "IPR001752:Kinesin motor domain, IPR019821:Kinesin motor domain, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG3219 27-Aug-18 DroID_v2018_08 "Drer\zgc:103670, Drer\kif2c" Scer\KIP3 Cele\klp-7 "Xtro\kif2a, Xtro\kif2c" "Mmus\Kif24, Mmus\Kif2c, Mmus\Kif2b, Mmus\Kif2a" "Hsap\KIF24, Hsap\KIF2A, Hsap\KIF2C, Hsap\KIF2B" "mitotic cell cycle defective,viable" "mitosis & nuclear chromosome,microtubule" FBgn0032494 CG5945 - http://flybase.org/reports/FBgn0032494 protein_coding_gene - - extracellular space ; GO:0005615 | inferred from sequence or structural similarity with to "CT18564, CG5945, cg5945" IPR010562:Haemolymph juvenile hormone binding CG5945 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0265696 lncRNA:CR44503 - http://flybase.org/reports/FBgn0265696 non_protein_coding_gene - - - CR44503 - CR44503 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001943 l(2)26Ad lethal (2) 26Ad http://flybase.org/reports/FBgn0001943 - gene - - - "l(2)gdh-5, l(2)26Ad" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0005747 l(1)TK239 lethal (1) TK239 http://flybase.org/reports/FBgn0005747 - gene - - - "l239, l(1)TK239" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "eye,lamina" FBgn0014253 l(2)DA2 lethal (2) DA2 http://flybase.org/reports/FBgn0014253 - gene - - - "DA2, l(2)DA2" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0036580 PDCD-5 Programmed Cell Death 5 http://flybase.org/reports/FBgn0036580 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR002836 molecular_function ; GO:0003674 | no biological data available defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype programmed cell death ; GO:0012501 | inferred from biological aspect of ancestor with PANTHER:PTN000089997 positive regulation of innate immune response ; GO:0045089 | inferred from mutant phenotype positive regulation of apoptotic process ; GO:0043065 | inferred from sequence or structural similarity with HGNC:8764 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000089996 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000089997 "DMPDCD-5, CG13072, BcDNA:RE17056, PDCD-5, PDCD5" IPR002836:PDCD5-related protein CG13072 27-Aug-18 DroID_v2018_08 Drer\pdcd5 Scer\SDD2 Cele\D2005.3 Xtro\pdcd5 "Mmus\Pdcd5, Mmus\Pdcd5-ps" Hsap\PDCD5 "viable,fertile" DRSC09955 E -0.030048743 -0.079465965 -1.523417301 1.718770224 -0.915957609 -0.348538684 FBgn0014917 anon-72ABa anon-72ABa http://flybase.org/reports/FBgn0014917 - gene - - - anon-72ABa - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0052110 CG32110 - http://flybase.org/reports/FBgn0052110 protein_coding_gene SUMO-specific protease activity ; GO:0016929 | inferred from sequence or structural similarity with SGD:S000005941 protein desumoylation ; GO:0016926 | inferred from sequence or structural similarity with SGD:S000005941 - "anon-AE003540.1, CG32110" "IPR003653:Ulp1 protease family, C-terminal catalytic domain" CG32110 27-Aug-18 DroID_v2018_08 "Drer\senp3b, Drer\senp5, Drer\senp3a, Drer\senp2, Drer\si:dkey-21c19.3" Scer\ULP1 "Cele\ulp-3, Cele\ulp-2, Cele\ulp-1" - "Mmus\Gm5415, Mmus\Senp1, Mmus\AF366264, Mmus\Gm9839, Mmus\4930444G20Rik, Mmus\Senp2, Mmus\Senp3, Mmus\Senp5" "Hsap\SENP5, Hsap\SENP3, Hsap\SENP2, Hsap\SENP1" viable FBgn0053225 CG33225 - http://flybase.org/reports/FBgn0053225 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314" cellular_component ; GO:0005575 | no biological data available CG33225 "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan" CG33225 27-Aug-18 DroID_v2018_08 "Drer\habp2, Drer\tmprss4a, Drer\plat" - "Cele\try-1, Cele\try-3" - "Mmus\Tmprss4, Mmus\Egfbp2, Mmus\Plat, Mmus\Habp2, Mmus\Gzmk" "Hsap\TMPRSS4, Hsap\PLAT, Hsap\GZMK, Hsap\HABP2" FBgn0030823 TTLL1A - http://flybase.org/reports/FBgn0030823 protein_coding_gene - protein polyglutamylation ; GO:0018095 | inferred from electronic annotation with InterPro:IPR027750 - CG8918 "IPR004344:Tubulin-tyrosine ligase/Tubulin polyglutamylase, IPR027750:Tubulin polyglutamylase TTLL1" CG8918 27-Aug-18 DroID_v2018_08 "Drer\ttll9, Drer\ttll10, Drer\ttll5, Drer\ttll1, Drer\ttll2, Drer\ttl" Scer\PBY1 "Cele\ttll-9, Cele\ttll-5" "Xtro\ttll3, Xtro\ttl, Xtro\ttll5, Xtro\ttll1, Xtro\ttll2, Xtro\LOC100158544" "Mmus\Ttll5, Mmus\Ttll8, Mmus\Ttll9, Mmus\Ttll1, Mmus\Ttll2, Mmus\Ttll10, Mmus\Ttll3, Mmus\Ttl" "Hsap\TTLL5, Hsap\TTLL8, Hsap\TTLL3, Hsap\TTLL2, Hsap\TTL, Hsap\TTLL10, Hsap\TTLL9, Hsap\TTLL1, Hsap\ARPC4-TTLL3" viable FBgn0002507 l(3)SG68 lethal (3) SG68 http://flybase.org/reports/FBgn0002507 FBgn0004733 gene - - - "l(3)dsl-2, l(3)dsl2, l(3)A2, SG68, l(3)SG68" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" imaginal disc FBgn0067748 l(1)G0210 lethal (1) G0210 http://flybase.org/reports/FBgn0067748 gene - - - l(1)G0210 - - 27-Aug-18 DroID_v2018_08 - - - - - - male sterile FBgn0002953 nofG no object fixation G http://flybase.org/reports/FBgn0002953 - gene - - - nofG - - 27-Aug-18 DroID_v2018_08 - - - - - - behavior defective eye FBgn0038429 CG14882 - http://flybase.org/reports/FBgn0038429 protein_coding_gene [methionine synthase] reductase activity ; GO:0030586 | inferred from sequence or structural similarity with HGNC:7473 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001433, InterPro:IPR001709, InterPro:IPR003097, InterPro:IPR017927, InterPro:IPR017938, InterPro:IPR023173 methionine biosynthetic process ; GO:0009086 | inferred from sequence or structural similarity with HGNC:7473" - "BcDNA:SD10961, CG14882" "IPR001433:Oxidoreductase FAD/NAD(P)-binding, IPR001709:Flavoprotein pyridine nucleotide cytochrome reductase, IPR003097:FAD-binding, type 1, IPR017927:Ferredoxin reductase-type FAD-binding domain, IPR017938:Riboflavin synthase-like beta-barrel" CG14882 27-Aug-18 DroID_v2018_08 "Drer\mtrr, Drer\porb, Drer\nos2b, Drer\nos1, Drer\pora, Drer\nos2a" "Scer\NCP1, Scer\MET10" Cele\mtrr-1 "Xtro\nos1, Xtro\por, Xtro\mtrr, Xtro\nos2, Xtro\nos3" "Mmus\Nos2, Mmus\Por, Mmus\Mtrr, Mmus\Nos1, Mmus\Nos3" "Hsap\NOS2, Hsap\NOS1, Hsap\POR, Hsap\NOS3, Hsap\MTRR" viable FBgn0038029 GstD11 Glutathione S transferase D11 http://flybase.org/reports/FBgn0038029 protein_coding_gene glutathione transferase activity ; GO:0004364 | inferred from direct assay glutathione metabolic process ; GO:0006749 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with RGD:70952 "BcDNA:RE72392, cg17639, CG17639, DmGSTD11, GstD11, gstd11, GSTD11" "IPR004045:Glutathione S-transferase, N-terminal, IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold" CG17639 27-Aug-18 DroID_v2018_08 "Drer\gstt1a, Drer\vars, Drer\gstr, Drer\eef1g, Drer\eef1e1, Drer\gstt2, Drer\mars, Drer\gstt1b" "Scer\GTT1, Scer\CAM1, Scer\TEF4, Scer\GTT2, Scer\YGR201C, Scer\URE2" Cele\gst-34 "Xtro\eef1e1, Xtro\eef1g, Xtro\gstt1" "Mmus\Gstt4, Mmus\Vars, Mmus\Eef1e1, Mmus\Mars, Mmus\Gstt1, Mmus\Gstt2, Mmus\Eef1g, Mmus\Gstt3" "Hsap\EEF1E1, Hsap\GSTT1, Hsap\MARS, Hsap\GSTT2, Hsap\VARS, Hsap\EEF1G, Hsap\GSTT2B" "viable,fertile" FBgn0260255 GSd226 - http://flybase.org/reports/FBgn0260255 gene - - - GSd226 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,neuroanatomy defective" ventral nerve cord FBgn0039103 CG13819 - http://flybase.org/reports/FBgn0039103 protein_coding_gene - - - CG13819 - - 27-Aug-18 DroID_v2018_08 - - - - - - DRSC14669 I -0.169621679 4.818628291 0.59764478 0.699219966 0.125739588 -0.867770565 FBgn0267351 Topors Topoisomerase I-interacting protein http://flybase.org/reports/FBgn0267351 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 DNA binding ; GO:0003677 | contributes_to inferred from direct assay lamin binding ; GO:0005521 | inferred from direct assay zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin protein ligase activity ; GO:0061630 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P08970 inferred from physical interaction with UniProtKB:Q86B87 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P14003 "protein polyubiquitination ; GO:0000209 | inferred from direct assay centrosome separation ; GO:0051299 | inferred from mutant phenotype meiotic chromosome condensation ; GO:0010032 | inferred from mutant phenotype mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from direct assay male meiosis ; GO:0007140 | inferred from mutant phenotype protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from direct assay male meiosis chromosome segregation ; GO:0007060 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from genetic interaction with UniProtKB:P14003 nuclear membrane organization ; GO:0071763 | inferred from mutant phenotype nucleus organization ; GO:0006997 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay nuclear lamina ; GO:0005652 | inferred from direct assay "CG15104, Topors, dtopors, nbl, dTopors, TOPORS" "IPR001841:Zinc finger, RING-type, IPR017907:Zinc finger, RING-type, conserved site, IPR018957:Zinc finger, C3HC4 RING-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR015943:WD40/YVTN repeat-like-containing domain" CG15104 27-Aug-18 DroID_v2018_08 "Drer\toporsa, Drer\toporsb" - "Cele\C32D5.11, Cele\C32D5.10" Xtro\topors "Mmus\Toporsl, Mmus\Topors" Hsap\TOPORS DRSC06531 I -0.762372109 1.654920577 0.585662723 -1.185527546 0.456563597 0.994001174 FBgn0015760 Map85 Microtubule-associated protein 85 http://flybase.org/reports/FBgn0015760 - gene - - microtubule associated complex ; GO:0005875 | inferred from direct assay "DMAP-85, Map85" - - 27-Aug-18 DroID_v2018_08 - - - - - - embryonic stage&& larval stage&& adult stage " embryonic stage | early , embryonic stage | 10-15hr , larval stage , embryonic stage | late , embryonic stage | 5hr , embryonic stage | mid , embryonic stage | 1-4hr , embryonic stage | 6-9hr " " longitudinal connective

, embryonic central nervous system

, connective

, amnioserosa

" FBgn0005182 l(2)S4 lethal of Seto 4 http://flybase.org/reports/FBgn0005182 - gene - - - l(2)S4 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal "puparium,epidermis" FBgn0085825 CR41619 - http://flybase.org/reports/FBgn0085825 rRNA_gene - - - CR41619 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0024725 Su(var)28D Su(var)28D http://flybase.org/reports/FBgn0024725 - gene - - - Su(var)28D - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005469 l(1)ts340 lethal (1) ts340 http://flybase.org/reports/FBgn0005469 FBgn0001830 gene - - - l(1)ts340 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,heat sensitive" FBgn0051816 CG31816 - http://flybase.org/reports/FBgn0051816 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs19f07, NEST:bs34h07, NEST:bs11b11, CG31816" - CG31816 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC01547 I -0.357568355 -1.569204021 -0.36647446 0.419010155 0.299510954 0.072152828 FBgn0016807 l(1)K9 lethal (1) K9 http://flybase.org/reports/FBgn0016807 - gene - - - "l(1)K9, K9" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0023140 WppC White prepupal locus C http://flybase.org/reports/FBgn0023140 - gene - - - "6, 3, 12, WppC" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263617 lncRNA:CR43626 - http://flybase.org/reports/FBgn0263617 non_protein_coding_gene - - - CR43626 - CR43626 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060847 l(3)S048716b lethal (3) S048716b http://flybase.org/reports/FBgn0060847 gene - - - "0487/16, l(3)S048716b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0025746 l(3)99Fa lethal (3) 99Fa http://flybase.org/reports/FBgn0025746 - gene - - - l(3)99Fa - - 27-Aug-18 DroID_v2018_08 - - - - - - "mitotic cell cycle defective,lethal - all die before end of larval stage,some die during larval stage" FBgn0026222 l(3)03608 lethal (3) 03608 http://flybase.org/reports/FBgn0026222 - gene - - - l(3)03608 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0029523 CR18275 - http://flybase.org/reports/FBgn0029523 pseudogene_attribute - - - "CR18275, CG18275" - CR18275 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,partially lethal - majority die" FBgn0043980 Su(rst)J45 Su(rst)J45 http://flybase.org/reports/FBgn0043980 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "J45, Su(rst)J45" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0008646 E5 E5 http://flybase.org/reports/FBgn0008646 FBgn0038187 protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017970 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR017970" - "CG9930, E5" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR009057:Homeobox domain-like" CG9930 27-Aug-18 DroID_v2018_08 "Drer\vax2, Drer\emx2, Drer\emx1, Drer\vax1, Drer\noto, Drer\emx3" - "Cele\ceh-23, Cele\ceh-2, Cele\ceh-99" "Xtro\emx2, Xtro\emx1.2, Xtro\not, Xtro\vax1" "Mmus\Emx1, Mmus\Vax2, Mmus\Noto, Mmus\Emx2, Mmus\Vax1" "Hsap\HOXA13, Hsap\VAX2, Hsap\NOTO, Hsap\EMX2, Hsap\VAX1, Hsap\EMX1, Hsap\NKX1-1" viable FBgn0033603 Cpr47Ef Cuticular protein 47Ef http://flybase.org/reports/FBgn0033603 protein_coding_gene structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr47Ef, CG13214, DmelCpr47Ef" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG13214 27-Aug-18 DroID_v2018_08 "Drer\zgc:113232, Drer\LOC100003040, Drer\LOC100537277" - "Cele\math-34, Cele\F44F1.4, Cele\sdz-30" Xtro\col9a3 "Mmus\H2-K1, Mmus\2410137M14Rik" - FBgn0032843 CG10730 - http://flybase.org/reports/FBgn0032843 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR017849, InterPro:IPR017850" "metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR017849, InterPro:IPR017850 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern" extracellular space ; GO:0005615 | inferred from direct assay "38B.7, CG10730, gi21430366, gi7298655" "IPR017849:Alkaline phosphatase-like, alpha/beta/alpha, IPR004245:Protein of unknown function DUF229, IPR017850:Alkaline-phosphatase-like, core domain" CG10730 27-Aug-18 DroID_v2018_08 - - "Cele\Y38A10A.2, Cele\Y41E3.1, Cele\R03G8.1, Cele\Y73F8A.35, Cele\R03G8.3, Cele\T07G12.3, Cele\M03F8.5, Cele\F10C2.3, Cele\F15H10.7, Cele\F07C3.3, Cele\K03A11.4, Cele\F32G8.2, Cele\T23E1.1, Cele\F32D8.2" - - - viable FBgn0000458 dis distorted eye http://flybase.org/reports/FBgn0000458 - gene - - - dis - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "eye,macrochaeta,wing,wing vein" FBgn0039071 bb8 big bubble 8 http://flybase.org/reports/FBgn0039071 protein_coding_gene glutamate dehydrogenase (NAD+) activity ; GO:0004352 | inferred from electronic annotation with InterPro:IPR033922 glutamate dehydrogenase [NAD(P)+] activity ; GO:0004353 | inferred from sequence or structural similarity with UniProt:P49448 inferred from sequence or structural similarity with UniProtKB:P00367 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006095, InterPro:IPR006096, InterPro:IPR006097, InterPro:IPR014362 cellular amino acid metabolic process ; GO:0006520 | inferred from electronic annotation with InterPro:IPR006095, InterPro:IPR006096, InterPro:IPR006097 mitochondrion organization ; GO:0007005 | inferred from mutant phenotype glutamate catabolic process to 2-oxoglutarate ; GO:0019551 | inferred from sequence or structural similarity with UniProt:P49448 inferred from sequence or structural similarity with UniProtKB:P00367 spermatogenesis ; GO:0007283 | inferred from mutant phenotype" mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProt:P49448 inferred from sequence or structural similarity with UniProtKB:P00367 "CG4434, bb8" "IPR006095:Glutamate/phenylalanine/leucine/valine dehydrogenase, IPR006096:Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal, IPR006097:Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain, IPR014362:Glutamate dehydrogenase, IPR016040:NAD(P)-binding domain, IPR033922:NAD(P) binding domain of glutamate dehydrogenase, IPR033524:Leu/Phe/Val dehydrogenases active site" CG4434 27-Aug-18 DroID_v2018_08 "Drer\glud1b, Drer\glud1a" "Scer\GDH1, Scer\GDH3" Cele\gdh-1 Xtro\glud1 Mmus\Glud1 "Hsap\GLUD1, Hsap\GLUD2" viable FBgn0266405 lncRNA:CR45045 - http://flybase.org/reports/FBgn0266405 non_protein_coding_gene - - - CR45045 - CR45045 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0027646 l(2)k09017a lethal (2) k09017a http://flybase.org/reports/FBgn0027646 - gene - - - l(2)k09017a - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0034724 babos babos http://flybase.org/reports/FBgn0034724 protein_coding_gene - regulation of dendrite morphogenesis ; GO:0048814 | inferred from mutant phenotype perivitelline space ; GO:0098595 | inferred from direct assay "CT12183, babos, CG3624" "IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR013151:Immunoglobulin" CG3624 27-Aug-18 DroID_v2018_08 "Drer\kirrelb, Drer\kirrel3l, Drer\dscama, Drer\si:ch1073-459j12.1, Drer\lrit3a, Drer\itgb4, Drer\igsf9bb, Drer\paplna, Drer\sdk1a, Drer\kirrel3a, Drer\sdk1b, Drer\igsf9a, Drer\kirrel3b, Drer\lrit1b, Drer\kirrela, Drer\ncam1b, Drer\lrit1a, Drer\ush2a, Drer\lrit3b" - - "Xtro\lrit3, Xtro\igsf9b, Xtro\papln, Xtro\kirrel2" "Mmus\Kirrel3, Mmus\Ptprq, Mmus\Kirrel, Mmus\Lrit1, Mmus\Lrit3, Mmus\Papln, Mmus\Igsf9b, Mmus\Sdk1, Mmus\Kirrel2" "Hsap\KIRREL, Hsap\KIRREL2, Hsap\PAPLN, Hsap\USH2A, Hsap\LRIT1, Hsap\LRIT3, Hsap\SDK1, Hsap\IGSF9B, Hsap\KIRREL3" "neuroanatomy defective,viable,partially lethal - majority die,some die during pupal stage" "embryonic/larval salivary gland,embryonic/larval hemocyte | third instar larval stage,dendrite | third instar larval stage,LNv neuron" FBgn0031952 cdc14 cell division cycle 14 http://flybase.org/reports/FBgn0031952 protein_coding_gene protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | inferred from electronic annotation with InterPro:IPR000340 protein serine/threonine phosphatase activity ; GO:0004722 | inferred from biological aspect of ancestor with PANTHER:PTN000596949 protein tyrosine phosphatase activity ; GO:0004725 | inferred from biological aspect of ancestor with PANTHER:PTN000596945 protein tyrosine phosphatase activity ; GO:0004725 | inferred from sequence or structural similarity with HGNC:1719 protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | non-traceable author statement protein serine/threonine phosphatase activity ; GO:0004722 | inferred from sequence or structural similarity with HGNC:1719 mitotic cell cycle arrest ; GO:0071850 | inferred from biological aspect of ancestor with PANTHER:PTN000596949 peptidyl-tyrosine dephosphorylation ; GO:0035335 | inferred from sequence or structural similarity with HGNC:1719 cilium assembly ; GO:0060271 | inferred from biological aspect of ancestor with PANTHER:PTN000596949 mitotic spindle midzone assembly ; GO:0051256 | inferred from biological aspect of ancestor with PANTHER:PTN000596949 regulation of exit from mitosis ; GO:0007096 | inferred from biological aspect of ancestor with PANTHER:PTN000596949 protein dephosphorylation ; GO:0006470 | non-traceable author statement spindle pole ; GO:0000922 | inferred from biological aspect of ancestor with PANTHER:PTN000596949 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000596947 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000596945 centrosome ; GO:0005813 | inferred from biological aspect of ancestor with PANTHER:PTN000596949 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:1719 mitotic spindle ; GO:0072686 | inferred from biological aspect of ancestor with PANTHER:PTN000596949 "CDC14, cdc14, CG7134, CDC-14, Cdc14" "IPR000387:Tyrosine specific protein phosphatases domain, IPR000340:Dual specificity phosphatase, catalytic domain, IPR016130:Protein-tyrosine phosphatase, active site, IPR029260:Dual specificity/tyrosine protein phosphatase, N-terminal, IPR029021:Protein-tyrosine phosphatase-like, IPR026070:Tyrosine-protein phosphatase CDC14, IPR003595:Protein-tyrosine phosphatase, catalytic, IPR020422:Dual specificity protein phosphatase domain" CG7134 27-Aug-18 DroID_v2018_08 "Drer\cdkn3, Drer\cdc14b, Drer\cdc14aa, Drer\dusp23b, Drer\cdc14ab, Drer\dusp23a, Drer\ptpdc1b, Drer\ptpdc1a" Scer\CDC14 Cele\cdc-14 "Xtro\dusp23, Xtro\cdc14a, Xtro\cdc14b, Xtro\ptpdc1" "Mmus\Dusp23, Mmus\Cdc14a, Mmus\Ptpdc1, Mmus\Cdkn3, Mmus\Cdc14b" "Hsap\CDC14A, Hsap\PTPDC1, Hsap\CDKN3, Hsap\CDC14B, Hsap\DUSP23" "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" embryonic/larval hemocyte | third instar larval stage FBgn0010902 l(3)06803 lethal (3) 06803 http://flybase.org/reports/FBgn0010902 - gene - - - l(3)06803 - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0262592 CG43127 - http://flybase.org/reports/FBgn0262592 protein_coding_gene - - - "CG43127, CG42519, CG34237, CG42520" - CG43127 27-Aug-18 DroID_v2018_08 "Drer\unc93b1, Drer\unc93a" - - "Xtro\unc93a, Xtro\unc93b1" "Mmus\Gm9992, Mmus\Unc93a, Mmus\Unc93b1" "Hsap\UNC93A, Hsap\UNC93B1" FBgn0265866 lncRNA:CR44655 - http://flybase.org/reports/FBgn0265866 non_protein_coding_gene - - - "lincRNA.990, CR44655" - CR44655 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033324 CG14744 - http://flybase.org/reports/FBgn0033324 protein_coding_gene - transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR004837 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR004837 CG14744 IPR004837:Sodium/calcium exchanger membrane region CG14744 27-Aug-18 DroID_v2018_08 "Drer\slc24a4b, Drer\slc8b1" "Scer\ECM27, Scer\YDL206W" "Cele\ncx-7, Cele\ncx-10, Cele\ncx-8, Cele\ncx-9, Cele\ncx-6" Xtro\slc8b1 "Mmus\Slc8b1, Mmus\Slc24a3, Mmus\Slc24a4" "Hsap\SLC24A3, Hsap\SLC8B1, Hsap\SLC24A4" viable FBgn0000970 Fs(2)Etr Female sterile (2) Etre http://flybase.org/reports/FBgn0000970 - gene - - - "Etre, Fs(2)Sz4, Fs(2)Etr" - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile soma-dependent,dominant" "dorsal appendage,egg,chorion" FBgn0033058 CCHa2-R CCHamide-2 receptor http://flybase.org/reports/FBgn0033058 protein_coding_gene neuropeptide receptor activity ; GO:0008188 | inferred from direct assay neuropeptide receptor activity ; GO:0008188 | inferred from sequence model G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence model "anon-WO0131005.23, CG14594, CG14593, CCHa2-R, CCHa2r" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR001556:Bombesin receptor-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG14593 27-Aug-18 DroID_v2018_08 "Drer\ednrab, Drer\gpr37a, Drer\gpr37l1a, Drer\ednrbb, Drer\nmbr, Drer\gpr37b, Drer\ednrba, Drer\si:ch211-119o8.4, Drer\gpr37l1b, Drer\grpr, Drer\ednraa" - Cele\npr-4 "Xtro\grpr, Xtro\gpr37, Xtro\ednrb2, Xtro\brs3, Xtro\ednrb, Xtro\ednra" "Mmus\Ednra, Mmus\Ednrb, Mmus\Brs3, Mmus\Nmbr, Mmus\Gpr37l1, Mmus\Gpr37, Mmus\Grpr" "Hsap\EDNRB, Hsap\GRPR, Hsap\EDNRA, Hsap\BRS3, Hsap\NMBR, Hsap\GPR37L1, Hsap\GPR37" viable DRSC04870 EK -0.398587106 0.732574989 -0.173721557 2.727721214 2.091305807 0.151875494 FBgn0038888 CheB93a Chemosensory protein B 93a http://flybase.org/reports/FBgn0038888 protein_coding_gene lipid binding ; GO:0008289 | inferred from sequence alignment with HGNC:14537 detection of pheromone ; GO:0043695 | inferred from expression pattern sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with CheB42a extracellular space ; GO:0005615 | inferred from sequence or structural similarity with CheB42a extracellular region ; GO:0005576 | inferred from sequence model "CG15503, CheB93a" "IPR006601:Uncharacterised protein family DM11, Drosophila melanogaster" CG15503 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0267159 lncRNA:CR45599 - http://flybase.org/reports/FBgn0267159 non_protein_coding_gene - - - CR45599 - CR45599 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065831 l(2)SH0349 lethal (2) SH0349 http://flybase.org/reports/FBgn0065831 gene - - - "l(2)SH0349, l(2)SH2 0349" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0028664 VhaM9.7-c Vacuolar H[+] ATPase M9.7 subunit c http://flybase.org/reports/FBgn0028664 protein_coding_gene "proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | contributes_to inferred from sequence model proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from biological aspect of ancestor with PANTHER:PTN000262636" "ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from electronic annotation with InterPro:IPR008389, InterPro:IPR017385 ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from sequence model" "proton-transporting V-type ATPase, V0 domain ; GO:0033179 | inferred from electronic annotation with InterPro:IPR008389, InterPro:IPR017385 vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220 | inferred from sequence or structural similarity plasma membrane proton-transporting V-type ATPase complex ; GO:0033181 | inferred from biological aspect of ancestor with PANTHER:PTN000262688 vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220 | inferred from sequence model" "CG11589, vhaM9.7-1, vhaM9.2-1, VhaM9.7-c, vhaM9.7-3, VhaM9.7-1, VhaM9.7-3" "IPR008389:ATPase, V0 complex, subunit e1/e2, IPR017385:ATPase, V0 complex, subunit e1/e2, metazoa" CG11589 27-Aug-18 DroID_v2018_08 "Drer\pars2, Drer\atp6v0e1, Drer\atpv0e2" Scer\VMA9 Cele\vha-17 "Xtro\atp6v0e2, Xtro\atp6v0e1" "Mmus\Atp6v0e, Mmus\Atp6v0e2, Mmus\Pars2" "Hsap\ATP6V0E1, Hsap\ATP6V0E2" "viable,visible" trichogen cell FBgn0260326 GSd243 - http://flybase.org/reports/FBgn0260326 gene - - - GSd243 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,neuroanatomy defective" "ventral nerve cord,longitudinal connective,segmental nerve" FBgn0005334 podH podoptera of Hannah http://flybase.org/reports/FBgn0005334 - gene - - - "pod-H, podH" - - 27-Aug-18 DroID_v2018_08 - - - - - - visible wing FBgn0260506 Pkc53E::Mmus\Rtkn - http://flybase.org/reports/FBgn0260506 engineered_fusion_gene - - - "Pkc53E::Mmus\Rtkn, Rhot-53E" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0084211 W145 W145 http://flybase.org/reports/FBgn0084211 gene - - - W145 - - 27-Aug-18 DroID_v2018_08 - - - - - - eye color defective pigment cell FBgn0026352 Su(SuRaf1)A2-1 Su(SuRaf1)A2-1 http://flybase.org/reports/FBgn0026352 - gene - - - "Su[Su(Raf)1]A2-1, Su(SuRaf1)A2-1" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0001647 l(1)dn27 lethal (1) discs normal 27 http://flybase.org/reports/FBgn0001647 - gene - - - "l(1)d.norm.-27, l(1)dn27" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0032184 CG13135 - http://flybase.org/reports/FBgn0032184 protein_coding_gene - - - CG13135 - CG13135 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0028272 l(1)G0433 lethal (1) G0433 http://flybase.org/reports/FBgn0028272 gene - - - l(1)G0433 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0266084 Fhos Formin homology 2 domain containing http://flybase.org/reports/FBgn0266084 protein_coding_gene actin binding ; GO:0003779 | inferred from sequence or structural similarity "muscle system process ; GO:0003012 | inferred from expression pattern inferred from genetic interaction with Mhc positive regulation of substrate adhesion-dependent cell spreading ; GO:1900026 | inferred from mutant phenotype positive regulation of cell migration ; GO:0030335 | inferred from mutant phenotype muscle cell cellular homeostasis ; GO:0046716 | inferred from mutant phenotype inferred from genetic interaction with Dg inferred from genetic interaction with Dys salivary gland histolysis ; GO:0035070 | inferred from mutant phenotype trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype programmed cell death involved in cell development ; GO:0010623 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype positive regulation of stress fiber assembly ; GO:0051496 | inferred from mutant phenotype inferred from genetic interaction with Rok wound healing, spreading of cells ; GO:0044319 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay "Fhos, jaz, CG32030, l(3)01629, CG42610, CG5797, CG5775, dFHOS, CG32025, desert, knit" "IPR014768:Rho GTPase-binding/formin homology 3 (GBD/FH3) domain, IPR015425:Formin, FH2 domain, IPR014767:Diaphanous autoregulatory (DAD) domain, IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical" CG42610 27-Aug-18 DroID_v2018_08 "Drer\fhod1, Drer\fhod3a, Drer\fhod3b" "Scer\BNI1, Scer\BNR1" Cele\fhod-1 "Xtro\fhod1, Xtro\fhod3" "Mmus\Fhod1, Mmus\Fhod3" "Hsap\FHOD3, Hsap\FHOD1" FBgn0036725 CG18265 - http://flybase.org/reports/FBgn0036725 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - "CG18265, ORE-10" IPR013087:Zinc finger C2H2-type CG18265 27-Aug-18 DroID_v2018_08 Drer\znf800a - Cele\die-1 Xtro\znf800 Mmus\Zfp800 Hsap\ZNF91 "viable,fertile" DRSC10310 K -0.541188368 0.480334065 0.344347236 0.138431369 0.807926603 -1.737453188 FBgn0250755 CG42233 - http://flybase.org/reports/FBgn0250755 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42233, CG11574, CG2112" "IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR019775:WD40 repeat, conserved site" CG42233 27-Aug-18 DroID_v2018_08 Drer\dcaf5 - "Cele\R11D1.1, Cele\adpr-1" - Mmus\Dcaf5 Hsap\DCAF5 FBgn0003512 Sry-delta Serendipity delta http://flybase.org/reports/FBgn0003512 FBgn0014946 protein_coding_gene "DNA binding ; GO:0003677 | inferred from direct assay transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | inferred from direct assay" "bicoid mRNA localization ; GO:0045450 | inferred from mutant phenotype multicellular organism reproduction ; GO:0032504 | inferred from expression pattern anterior/posterior axis specification, embryo ; GO:0008595 | inferred from mutant phenotype inferred from genetic interaction with bcd oogenesis ; GO:0048477 | inferred from genetic interaction with bcd positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay" nucleus ; GO:0005634 | inferred from direct assay polytene chromosome interband ; GO:0005705 | inferred from direct assay "srydelta, sry-delta, sry, EH8, Sry delta, Sry-delta, sry delta, Srydelta, anon-EH8, CG17958" IPR013087:Zinc finger C2H2-type CG17958 27-Aug-18 DroID_v2018_08 "Drer\zgc:171551, Drer\znf1051, Drer\si:dkey-237m9.1, Drer\si:dkey-261j4.4, Drer\im:7141269, Drer\znf1069, Drer\si:dkeyp-113d7.1, Drer\znf1136, Drer\si:dkey-261j4.5, Drer\zgc:113209, Drer\znf1007, Drer\znf1059, Drer\si:ch73-367f21.6, Drer\LOC100537687, Drer\drl, Drer\zgc:173714, Drer\zgc:174646, Drer\LOC100151333, Drer\LOC108183935, Drer\znf1070, Drer\znf1041, Drer\znf1078, Drer\si:dkey-261j4.3" - Cele\sdz-12 - - "Hsap\GZF1, Hsap\ZNF200, Hsap\ZNF449" " adult stage && oogenesis stage | stage >S10B , oogenesis stage | stage , nurse cell

, organism

" " embryonic stage | stage 12-17 , embryonic stage | stage >5 , embryonic stage | stage <5 , adult stage && oogenesis stage , adult stage && oogenesis stage | stage S>12 " " embryonic/larval pharynx

,

, nurse cell

, ventral nerve cord

, supraesophageal ganglion

, oocyte , follicle cell

" "wild-type,lethal,recessive,partially" "testis,embryonic/first instar larval cuticle,embryonic/first instar larval cuticle & thoracic segment,telson,posterior,gonad,male,spermatozoon,cephalopharyngeal skeleton" FBgn0038113 CG11668 - http://flybase.org/reports/FBgn0038113 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP115, CG11668" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG11668 27-Aug-18 DroID_v2018_08 Drer\f10 - "Cele\try-1, Cele\svh-1" - Mmus\F9 "Hsap\F10, Hsap\MASP1, Hsap\PROC, Hsap\F7" viable FBgn0262734 eIF4H1 eukaryotic translation initiation factor 4H1 http://flybase.org/reports/FBgn0262734 protein_coding_gene translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity ribosomal small subunit binding ; GO:0043024 | inferred from biological aspect of ancestor with PANTHER:PTN000579859 RNA strand annealing activity ; GO:0033592 | inferred from biological aspect of ancestor with PANTHER:PTN000579859 translation initiation factor activity ; GO:0003743 | inferred from biological aspect of ancestor with PANTHER:PTN000579859 RNA strand-exchange activity ; GO:0034057 | inferred from biological aspect of ancestor with PANTHER:PTN000579859 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity formation of translation preinitiation complex ; GO:0001731 | inferred from biological aspect of ancestor with PANTHER:PTN000579859 eukaryotic translation initiation factor 4F complex assembly ; GO:0097010 | inferred from biological aspect of ancestor with PANTHER:PTN000579859 translational initiation ; GO:0006413 | inferred from sequence or structural similarity cytoplasmic translation ; GO:0002181 | inferred from biological aspect of ancestor with PANTHER:PTN000579859 eukaryotic translation initiation factor 4F complex ; GO:0016281 | inferred from biological aspect of ancestor with PANTHER:PTN000579859 polysome ; GO:0005844 | inferred from biological aspect of ancestor with PANTHER:PTN000579859 microtubule associated complex ; GO:0005875 | inferred from direct assay cytosol ; GO:0005829 | inferred from sequence or structural similarity "Rbp2, eIF4H, cg4429, CG4429, RRM2, rrm2, anon-EST:fe1B9, MRE9, eIF4H1" "IPR034229:eIF4H, RNA recognition motif, IPR000504:RNA recognition motif domain" CG4429 27-Aug-18 DroID_v2018_08 "Drer\hnrnpabb, Drer\ncoa5, Drer\eif4ba, Drer\raly, Drer\hnrnpd, Drer\zgc:55733, Drer\hnrnpaba, Drer\trnau1apb, Drer\cirbpa, Drer\hnrnpa3, Drer\hnrnpc, Drer\trnau1apa, Drer\srsf10a, Drer\eif4h, Drer\rbm34, Drer\zcrb1, Drer\hnrnpa1b, Drer\wu:fq32h04, Drer\eif4bb, Drer\dazl" "Scer\MRN1, Scer\NAB6, Scer\NOP6, Scer\MUD1, Scer\NGR1, Scer\TIF3, Scer\NOP12, Scer\CWC2, Scer\NAM8" "Cele\H05C05.1, Cele\drr-2" "Xtro\dazl, Xtro\cirbp, Xtro\raly, Xtro\hnrnpa2b1, Xtro\trnau1ap, Xtro\hnrnpdl, Xtro\hnrnpa1, Xtro\hnrnpab, Xtro\eif4b, Xtro\rbm34, Xtro\hnrnpc, Xtro\ralyl, Xtro\hnrnpa3, Xtro\hnrnpd, Xtro\eif4h" "Mmus\Eif4b, Mmus\Hnrnpd, Mmus\Srsf10, Mmus\Zcrb1, Mmus\Slirp, Mmus\Trnau1ap, Mmus\Gm21379, Mmus\Hnrnpab, Mmus\Hnrnpc, Mmus\Hnrnpa1, Mmus\Rbm34, Mmus\Raly, Mmus\Cirbp, Mmus\Eif4h, Mmus\Hnrnpa3, Mmus\Tra2b, Mmus\Boll, Mmus\Dazl, Mmus\Rbm31y, Mmus\Hnrnpa2b1, Mmus\Srsf12" "Hsap\DAZ4, Hsap\SRSF10, Hsap\EIF4B, Hsap\CIRBP, Hsap\RALY, Hsap\DAZ2, Hsap\HNRNPCL1, Hsap\DAZ1, Hsap\DAZ3, Hsap\EIF4H, Hsap\HNRNPD, Hsap\HNRNPA2B1, Hsap\RBM3, Hsap\RBM34, Hsap\HNRNPA1, Hsap\RALYL, Hsap\HNRNPA1L2, Hsap\HNRNPA3, Hsap\DAZL, Hsap\HNRNPAB, Hsap\TRNAU1AP, Hsap\SLIRP, Hsap\HNRNPC, Hsap\BOLL" FBgn0259855 Su(Ste):CR42424 Su(Ste):CR42424 http://flybase.org/reports/FBgn0259855 non_protein_coding_gene - - - "Su(Ste):CR42424, CR42424" - CR42424 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267889 CR46177 - http://flybase.org/reports/FBgn0267889 pseudogene_attribute - - - CR46177 - CR46177 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0017386 l(1)15De lethal (1) 15De http://flybase.org/reports/FBgn0017386 - gene - - - l(1)15De - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0003633 Su(var)327 Suppressor of variegation 327 http://flybase.org/reports/FBgn0003633 - gene - - - "Su(var)327, 327" - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,suppressor of variegation,dominant,non-suppressor of variegation" FBgn0029696 CG15571 - http://flybase.org/reports/FBgn0029696 protein_coding_gene molecular_function ; GO:0003674 | no biological data available eggshell chorion assembly ; GO:0007306 | inferred from expression pattern inferred from genomic context chorion ; GO:0042600 | inferred from genomic context CG15571 - CG15571 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0011153 l(1)Q231 lethal (1) Q231 http://flybase.org/reports/FBgn0011153 FBgn0010210 gene - - - l(1)Q231 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0084515 S16.6 S16.6 http://flybase.org/reports/FBgn0084515 gene - - - S16.6 - - 27-Aug-18 DroID_v2018_08 - - - - - - eye color defective pigment cell FBgn0069202 l(2)46Fb lethal (2) 46Fb http://flybase.org/reports/FBgn0069202 gene - - - "6.6, 15.4, 10.5, B, l(2)46CFl, l(2)46CFg, l(2)46Fb" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,semidominant" FBgn0001878 l(1)YD23a lethal (1) YD23a http://flybase.org/reports/FBgn0001878 - gene - - - "l(1)YD23, l(1)YD23a" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0266514 s-535 - http://flybase.org/reports/FBgn0266514 gene - - - s-535 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0027651 l(2)44A lethal (2) 44A http://flybase.org/reports/FBgn0027651 - gene - - - l(2)44A - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0263316 Mrp4 Multidrug resistance protein 4 http://flybase.org/reports/FBgn0263316 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR011527, InterPro:IPR017871 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from biological aspect of ancestor with PANTHER:PTN000657997" "wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap response to hypoxia ; GO:0001666 | inferred from mutant phenotype response to oxidative stress ; GO:0006979 | inferred from mutant phenotype transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000657997 response to anoxia ; GO:0034059 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype" integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000658000 "Mrp4, CG14709, dMRP4, Dme_CG14709, CK01227, BEST:CK01227, BEST:CK02472, EP3221" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR011527:ABC transporter type 1, transmembrane domain, IPR017871:ABC transporter, conserved site" CG14709 27-Aug-18 DroID_v2018_08 "Drer\abcc4, Drer\abcc6b.2, Drer\abcc3, Drer\abcc1, Drer\abcc5, Drer\abcc13, Drer\abcc12, Drer\abcc9, Drer\abcc8, Drer\abcc2, Drer\abcc6a, Drer\abcc10, Drer\cftr, Drer\LOC100329706" "Scer\NFT1, Scer\STE6, Scer\VMR1, Scer\BPT1, Scer\YKR104W, Scer\YCF1, Scer\YBT1, Scer\YOR1" "Cele\mrp-7, Cele\mrp-2, Cele\mrp-8, Cele\mrp-3, Cele\mrp-5, Cele\mrp-1, Cele\mrp-6, Cele\mrp-4" "Xtro\abcc1, Xtro\abcc4, Xtro\abcc10, Xtro\abcc3, Xtro\abcc6, Xtro\cftr" "Mmus\Abcc12, Mmus\Cftr, Mmus\Abcc9, Mmus\Abcc3, Mmus\Abcc5, Mmus\Abcc2, Mmus\Abcc8, Mmus\Abcc10, Mmus\Abcc1, Mmus\Abcc6, Mmus\Abcc4" "Hsap\ABCC1, Hsap\ABCC6, Hsap\ABCC12, Hsap\ABCC3, Hsap\ABCC5, Hsap\CFTR, Hsap\ABCC4, Hsap\ABCC9, Hsap\ABCC10, Hsap\ABCC8, Hsap\ABCC2, Hsap\ABCC11" FBgn0001162 gustM gustatory-defective M http://flybase.org/reports/FBgn0001162 - gene - - - gustM - - 27-Aug-18 DroID_v2018_08 - - - - - - taste perception defective FBgn0067775 fragile-locus-A fragile locus A http://flybase.org/reports/FBgn0067775 gene molecular_function ; GO:0003674 | no biological data available egg activation ; GO:0007343 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fragile-locus-A - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,maternal effect" FBgn0002454 mdm many discs missing http://flybase.org/reports/FBgn0002454 FBgn0011654 gene - - - "l(3)J16, l(3)SG7, mdm" - - 27-Aug-18 DroID_v2018_08 - - - - - - "some die during larval stage,lethal - all die before end of larval stage,recessive" imaginal disc FBgn0267677 lncRNA:CR46013 - http://flybase.org/reports/FBgn0267677 non_protein_coding_gene - - - CR46013 - CR46013 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0013690 mt:tRNA:Cys-GCA mitochondrial transfer RNA:Cysteine-GCA http://flybase.org/reports/FBgn0013690 FBgn0002867 tRNA_gene - - - "CR34065, tRNAcys, tRNA[Cys], tRNA-Cys, mtdbD00006296, mt:tRNA:Cys-GCA, mt:tRNA:C" - CR34065 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0058112 CG40112 - http://flybase.org/reports/FBgn0058112 protein_coding_gene - - - CG40112 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265933 lncRNA:CR44722 - http://flybase.org/reports/FBgn0265933 non_protein_coding_gene - - - "CR44722, lincRNA.508" - CR44722 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000366 cr-3 cream 3 http://flybase.org/reports/FBgn0000366 - gene - - - cr-3 - - 27-Aug-18 DroID_v2018_08 - - - - - - "eye color defective,recessive" "Malpighian tubule,pigment cell" FBgn0038820 CG4000 - http://flybase.org/reports/FBgn0038820 protein_coding_gene - - - CG4000 - CG4000 27-Aug-18 DroID_v2018_08 Drer\col12a1a - "Cele\col-144, Cele\col-10, Cele\col-107, Cele\col-91" - - - "viable,fertile,visible,body color defective,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,mesothoracic tergum" FBgn0020305 dbe dribble http://flybase.org/reports/FBgn0020305 "FBgn0022118, FBgn0022171, FBgn0024894" protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR004088 "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000462 | inferred from biological aspect of ancestor with PANTHER:PTN000286619 rRNA processing ; GO:0006364 | inferred from mutant phenotype positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype" small-subunit processome ; GO:0032040 | inferred from biological aspect of ancestor with PANTHER:PTN000286619 nucleoplasm ; GO:0005654 | inferred from direct assay nucleolus ; GO:0005730 | inferred from direct assay "l(2)k06708, l(2)k05428, CG4258, dbe, DBE, dribble" "IPR004087:K Homology domain, IPR024166:Ribosomal RNA assembly KRR1, IPR004088:K Homology domain, type 1" CG4258 27-Aug-18 DroID_v2018_08 Drer\krr1 "Scer\PNO1, Scer\KRR1" Cele\C05C8.2 Xtro\krr1 Mmus\Krr1 Hsap\KRR1 "lethal,recessive,cell lethalcell lethal,somatic clone,lethal - all die before end of larval stage,some die during larval stage,visible,partially lethal - majority die,some die during pupal stage" "ovariole,germline clone,mesothoracic tergum" FBgn0053453 CG33453 - http://flybase.org/reports/FBgn0053453 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33453 IPR010512:Protein of unknown function DUF1091 CG33453 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0003708 tipC temperature-induced paralytic C http://flybase.org/reports/FBgn0003708 - gene - - - tipC - - 27-Aug-18 DroID_v2018_08 - - - - - - "paralytic,heat sensitive" FBgn0032378 CycY Cyclin Y http://flybase.org/reports/FBgn0032378 protein_coding_gene protein kinase binding ; GO:0019901 | inferred from electronic annotation with InterPro:IPR012399 regulation of cyclin-dependent protein serine/threonine kinase activity ; GO:0000079 | inferred from electronic annotation with InterPro:IPR012399 developmental growth ; GO:0048589 | inferred from mutant phenotype - "i182, anon-WO0118547.165, Dcyclin Y, CycY, CG14939" "IPR006671:Cyclin, N-terminal, IPR012399:Cyclin Y, IPR013763:Cyclin-like" CG14939 27-Aug-18 DroID_v2018_08 "Drer\ccnyl1, Drer\ccny" "Scer\LAM1, Scer\PHO80, Scer\SIP3" Cele\cyy-1 "Xtro\ccnyl1, Xtro\ccny" "Mmus\Ccnyl1, Mmus\Ccny" "Hsap\AGAP4, Hsap\CCNY, Hsap\CCNYL1" viable FBgn0266915 lncRNA:CR45375 - http://flybase.org/reports/FBgn0266915 non_protein_coding_gene - - - CR45375 - CR45375 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0003051 Pdr Purpleoider http://flybase.org/reports/FBgn0003051 - gene - - - Pdr - - 27-Aug-18 DroID_v2018_08 - - - - - - eye color defective pigment cell FBgn0267352 BG01272 - http://flybase.org/reports/FBgn0267352 gene - - - BG01272 - - 27-Aug-18 DroID_v2018_08 - - - - - - "short lived,male,heat stress response defective,female,starvation stress response defective" macrochaeta FBgn0038125 CG8141 - http://flybase.org/reports/FBgn0038125 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 ubiquitin-like protein conjugating enzyme binding ; GO:0044390 | inferred from biological aspect of ancestor with PANTHER:PTN000267874 ubiquitin protein ligase activity involved in ERAD pathway ; GO:1904264 | inferred from biological aspect of ancestor with PANTHER:PTN000267874 zinc ion binding ; GO:0008270 | inferred from sequence model ER-associated misfolded protein catabolic process ; GO:0071712 | inferred from biological aspect of ancestor with PANTHER:PTN000267874 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN000267874 Derlin-1 retrotranslocation complex ; GO:0036513 | inferred from biological aspect of ancestor with PANTHER:PTN000267874 "BcDNA:AT26376, CG8141" "IPR001841:Zinc finger, RING-type, IPR017907:Zinc finger, RING-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG8141 27-Aug-18 DroID_v2018_08 "Drer\rnf5, Drer\rnf185" Scer\SLX8 Cele\rnf-5 "Xtro\rnf185, Xtro\rnf5" "Mmus\Rnf185, Mmus\Rnf5" "Hsap\RNF185, Hsap\RNF5" viable FBgn0001134 Grd Glycine receptor http://flybase.org/reports/FBgn0001134 - protein_coding_gene GABA-gated chloride ion channel activity ; GO:0022851 | inferred from direct assay extracellular-glycine-gated ion channel activity ; GO:0016933 | inferred from sequence or structural similarity GABA-A receptor activity ; GO:0004890 | inferred from direct assay cation channel activity ; GO:0005261 | inferred from direct assay ligand-gated ion channel activity ; GO:0015276 | inferred from sequence or structural similarity ligand-gated ion channel activity ; GO:0015276 | inferred from direct assay ion transport ; GO:0006811 | inferred from direct assay "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR006028, InterPro:IPR006201 integral component of membrane ; GO:0016021 | traceable author statement plasma membrane ; GO:0005886 | inferred from sequence or structural similarity" "DmGABA(GRD), CG7446, GRD, Grd, CT22917" "IPR018000:Neurotransmitter-gated ion-channel, conserved site, IPR006028:Gamma-aminobutyric acid A receptor/Glycine receptor alpha, IPR006029:Neurotransmitter-gated ion-channel transmembrane domain, IPR006201:Neurotransmitter-gated ion-channel, IPR006202:Neurotransmitter-gated ion-channel ligand-binding domain" CG7446 27-Aug-18 DroID_v2018_08 "Drer\gabrp, Drer\gabrd, Drer\gabrg3, Drer\gabrr2b, Drer\gabrr3a, Drer\gabra3, Drer\glrbb, Drer\gabrb2, Drer\gabra1, Drer\glra3, Drer\si:dkey-155h10.3, Drer\LOC100001259, Drer\gabrb1, Drer\si:dkey-52k1.6, Drer\gabra5, Drer\LOC562831, Drer\gabrr2a, Drer\glra4a, Drer\zgc:110204, Drer\glra4b, Drer\gabrg2, Drer\gabrb3, Drer\gabrr1, Drer\glrba, Drer\LOC100330554, Drer\gabra6a, Drer\glra2, Drer\gabrb4, Drer\gabra6b" - "Cele\avr-14, Cele\ggr-1, Cele\gab-1, Cele\glc-2, Cele\glc-3, Cele\lgc-39, Cele\glc-4, Cele\lgc-44, Cele\lgc-41, Cele\lgc-42, Cele\lgc-38, Cele\lgc-40, Cele\unc-49, Cele\lgc-37, Cele\avr-15, Cele\lgc-36" "Xtro\gabrd, Xtro\gabrb3, Xtro\gabrr3, Xtro\gabra5, Xtro\glra2, Xtro\glrb, Xtro\glra3, Xtro\LOC100490720, Xtro\gabrp, Xtro\gabra6, Xtro\gabra3, Xtro\gabra2, Xtro\gabrg2, Xtro\glra1" "Mmus\Gabrg3, Mmus\Gabra4, Mmus\Glra2, Mmus\Glrb, Mmus\Gabrq, Mmus\Gabra1, Mmus\Gabrr2, Mmus\Gabrr3, Mmus\Gabrb3, Mmus\Gabra3, Mmus\Gabre, Mmus\Gabra2, Mmus\Gabrb1, Mmus\Gabrg1, Mmus\Gabrd, Mmus\Glra1, Mmus\Glra3, Mmus\Gabra5, Mmus\Glra4, Mmus\Gabrb2, Mmus\Gabra6, Mmus\Gabrr1, Mmus\Gabrg2, Mmus\Gabrp" "Hsap\GLRA2, Hsap\GABRA5, Hsap\GABRR1, Hsap\GLRA1, Hsap\GLRA4, Hsap\GABRB2, Hsap\GABRG2, Hsap\GABRB1, Hsap\GABRA3, Hsap\GABRG3, Hsap\GABRA2, Hsap\GABRG1, Hsap\GABRA1, Hsap\GABRD, Hsap\GABRR3, Hsap\GLRA3, Hsap\GLRB, Hsap\GABRE, Hsap\GABRR2, Hsap\GABRQ, Hsap\GABRP, Hsap\GABRB3, Hsap\GABRA4, Hsap\GABRA6" viable FBgn0044377 anon-AE003538.2 anon-AE003538.2 http://flybase.org/reports/FBgn0044377 gene - - - anon-AE003538.2 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040804 CG13453 - http://flybase.org/reports/FBgn0040804 protein_coding_gene - - - CG13453 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260386 mtg mind the gap http://flybase.org/reports/FBgn0260386 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 carbohydrate derivative binding ; GO:0097367 | inferred from direct assay chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 synapse assembly ; GO:0007416 | inferred from direct assay synaptic cleft ; GO:0043083 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay terminal bouton ; GO:0043195 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay "mtg, CG7549, 0849/10, l(3)S084910, l(3)S084910b, Mtg" "IPR002557:Chitin binding domain, IPR011991:Winged helix-turn-helix DNA-binding domain" CG7549 27-Aug-18 DroID_v2018_08 - - Cele\Y56A3A.6 - - - FBgn0036365 cmb combover http://flybase.org/reports/FBgn0036365 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with mwh imaginal disc-derived wing hair organization ; GO:0035317 | inferred from genetic interaction with mwh - "NEST:bs28e06, CG10732, cmb" - CG10732 27-Aug-18 DroID_v2018_08 Drer\pcm1 - - Xtro\pcm1 Mmus\Pcm1 Hsap\PCM1 viable FBgn0030266 CG11122 - http://flybase.org/reports/FBgn0030266 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - microtubule associated complex ; GO:0005875 | inferred from direct assay CG11122 "IPR011989:Armadillo-like helical, IPR013087:Zinc finger C2H2-type, IPR015943:WD40/YVTN repeat-like-containing domain" CG11122 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing vein,eye" FBgn0015517 ms(2)HB223 male sterile (2) HB223 http://flybase.org/reports/FBgn0015517 - gene - - - ms(2)HB223 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032935 Atg18b Autophagy-related 18b http://flybase.org/reports/FBgn0032935 protein_coding_gene - cellular response to oxidative stress ; GO:0034599 | inferred from direct assay - "l(2)k09410, CG8678, Atg18, Atg18-like, Atg18b, ATG18.2" "IPR017986:WD40-repeat-containing domain, IPR001680:WD40 repeat, IPR015943:WD40/YVTN repeat-like-containing domain" CG8678 27-Aug-18 DroID_v2018_08 "Drer\wipi2, Drer\LOC100332293, Drer\wipi1" "Scer\ATG18, Scer\ATG21" Cele\atg-18 Xtro\wipi1 "Mmus\Wipi1, Mmus\Wipi2" "Hsap\WIPI2, Hsap\WIPI1" "viable,lethal,recessive" DRSC03108 I 1.70367988 0.85034156 -0.01982464 0.269956615 0.058478325 -0.228434101 FBgn0267606 asRNA:CR45944 - http://flybase.org/reports/FBgn0267606 non_protein_coding_gene - - - CR45944 - CR45944 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004436 Ubc6 Ubiquitin conjugating enzyme 6 http://flybase.org/reports/FBgn0004436 FBgn0064873 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with SGD:S000003026 ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 p53 binding ; GO:0002039 | inferred from physical interaction with p53 ubiquitin conjugating enzyme activity ; GO:0061631 | inferred by curator from GO:0042787 protein domain specific binding ; GO:0019904 | inferred from physical interaction with UniProtKB:Q8IMZ4 "DNA repair ; GO:0006281 | inferred from genetic interaction with SGD:S000003026 negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype negative regulation of DNA damage response, signal transduction by p53 class mediator ; GO:0043518 | inferred from mutant phenotype negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator ; GO:1902166 | inferred from mutant phenotype endocytic recycling ; GO:0032456 | inferred from mutant phenotype protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from mutant phenotype mitophagy ; GO:0000422 | inferred from mutant phenotype positive regulation of proteasomal ubiquitin-dependent protein catabolic process ; GO:0032436 | inferred from mutant phenotype protein polyubiquitination ; GO:0000209 | inferred from biological aspect of ancestor with PANTHER:PTN000630651 centrosome organization ; GO:0051297 | inferred from mutant phenotype centrosome separation ; GO:0051299 | inferred from mutant phenotype histone ubiquitination ; GO:0016574 | inferred from biological aspect of ancestor with PANTHER:PTN000630651 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from mutant phenotype" HULC complex ; GO:0033503 | inferred from biological aspect of ancestor with PANTHER:PTN000630652 nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 nuclear chromatin ; GO:0000790 | inferred from biological aspect of ancestor with PANTHER:PTN000630652 cytoplasm ; GO:0005737 | inferred from direct assay "RAD6, Rad6, Dhr6, CG2013, BcDNA:RE56673, UbcD6, Rad6a, dRad6, dRAD6, Ubc6, UBC6" "IPR000608:Ubiquitin-conjugating enzyme E2, IPR016135:Ubiquitin-conjugating enzyme/RWD-like, IPR023313:Ubiquitin-conjugating enzyme, active site" CG2013 27-Aug-18 DroID_v2018_08 "Drer\ube2al, Drer\ube2a, Drer\ube2b" Scer\RAD6 Cele\ubc-1 "Xtro\ube2b, Xtro\ube2a" "Mmus\Ube2u, Mmus\Ube2b, Mmus\Ube2a" "Hsap\UBE2A, Hsap\UBE2B, Hsap\UBE2U" "lethal - all die before end of larval stage,recessive,neurophysiology defective,increased cell death,lethal,partially lethal - majority die,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuromuscular junction,mitochondrion | third instar larval stage,wing" DRSC12370 IEK -1.746964077 -1.14141391 -1.544899447 -1.01139816 1.898146923 -0.48485935 FBgn0065561 l(2)SH0991 lethal (2) SH0991 http://flybase.org/reports/FBgn0065561 gene - - - "l(2)SH0991, l(2)SH2 0991" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0029859 CG15892 - http://flybase.org/reports/FBgn0029859 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG32918, CG15892" - CG15892 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" FBgn0060332 l(3)S145613 lethal (3) S145613 http://flybase.org/reports/FBgn0060332 gene - - - "1456/13, l(3)S145613" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0266327 asRNA:CR44992 - http://flybase.org/reports/FBgn0266327 non_protein_coding_gene - - - CR44992 - CR44992 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0046639 anon-38D.6 anon-38D.6 http://flybase.org/reports/FBgn0046639 gene - - - "38D.6, anon-38D.6" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000437 df defective http://flybase.org/reports/FBgn0000437 - gene - - - df - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,partially lethal - majority live" "ocellar bristle,interocellar bristle" FBgn0037632 CCT7 Chaperonin containing TCP1 subunit 7 http://flybase.org/reports/FBgn0037632 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002194, InterPro:IPR002423, InterPro:IPR012720 protein binding involved in protein folding ; GO:0044183 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 unfolded protein binding ; GO:0051082 | inferred from biological aspect of ancestor with PANTHER:PTN000143677" 'de novo' protein folding ; GO:0006458 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 cytoplasmic microtubule organization ; GO:0031122 | inferred from mutant phenotype chaperone-mediated protein folding ; GO:0061077 | inferred from biological aspect of ancestor with PANTHER:PTN000143677 neurogenesis ; GO:0022008 | inferred from mutant phenotype mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from direct assay chaperonin-containing T-complex ; GO:0005832 | inferred from biological aspect of ancestor with PANTHER:PTN000143937 microtubule associated complex ; GO:0005875 | inferred from direct assay "CG8351, tcp-1eta, tcp1eta, Tcp-1-eta1, Tcp-1eta, Cct7, Q9VHL2_DROME, TCP1eta, TCPeta, CCT7, TCP1-eta" "IPR002194:Chaperonin TCP-1, conserved site, IPR002423:Chaperonin Cpn60/TCP-1 family, IPR012720:T-complex protein 1, eta subunit, IPR017998:Chaperone tailless complex polypeptide 1 (TCP-1), IPR027409:GroEL-like apical domain, IPR027413:GroEL-like equatorial domain" CG8351 27-Aug-18 DroID_v2018_08 "Drer\tcp1, Drer\mkks, Drer\cct7, Drer\bbs10" "Scer\CCT7, Scer\TCP1" Cele\cct-7 Xtro\cct7 "Mmus\Cct7, Mmus\Tcp1, Mmus\Mkks, Mmus\Bbs10" "Hsap\MKKS, Hsap\BBS10, Hsap\TCP1, Hsap\CCT7" "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0053505 U3-55K U3 small nuclear riboprotein factor 55K http://flybase.org/reports/FBgn0053505 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:16829 U3 snoRNA binding ; GO:0034511 | inferred from direct assay rRNA processing ; GO:0006364 | inferred from biological aspect of ancestor with PANTHER:PTN000458584 neurogenesis ; GO:0022008 | inferred from mutant phenotype box C/D snoRNP complex ; GO:0031428 | inferred from sequence or structural similarity with HGNC:16829 small-subunit processome ; GO:0032040 | inferred from biological aspect of ancestor with PANTHER:PTN000458584 nucleolus ; GO:0005730 | inferred from sequence or structural similarity with HGNC:16829 "CG10220, U3-55K, CG33505" "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG33505 27-Aug-18 DroID_v2018_08 Drer\rrp9 Scer\RRP9 "Cele\Y54E5B.2, Cele\T02H6.1" Xtro\rrp9 Mmus\Rrp9 Hsap\RRP9 "lethal,neuroanatomy defective,viable,visible" "ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0000838 fs(1)M24 female sterile (1) M24 http://flybase.org/reports/FBgn0000838 - gene - - - fs(1)M24 - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive,lethal,rescuable maternal effect,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "egg,maternal effect" FBgn0031434 insv insensitive http://flybase.org/reports/FBgn0031434 protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q24478 transcription corepressor activity ; GO:0003714 | inferred from physical interaction with Su(H) chromatin insulator sequence binding ; GO:0043035 | inferred from direct assay "negative regulation of Notch signaling pathway ; GO:0045746 | inferred from mutant phenotype inferred from genetic interaction with numb inferred from genetic interaction with N inferred from genetic interaction with Su(H) negative regulation of Notch signaling pathway ; GO:0045746 | inferred from mutant phenotype negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from direct assay" nucleus ; GO:0005634 | inferred from direct assay "CG3227, BcDNA:RE55538, insv, Insv" IPR018379:BEN domain CG3227 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible" "microchaeta,adult abdominal sensillum,tormogen cell,ectopic,trichogen cell,macrochaeta,supernumerary,wing margin" FBgn0010846 l(3)04696 lethal (3) 04696 http://flybase.org/reports/FBgn0010846 - gene - - - "4712, l(3)04696" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0285910 VhaAC39-1 Vacuolar H[+] ATPase AC39 subunit 1 http://flybase.org/reports/FBgn0285910 protein_coding_gene "proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from sequence or structural similarity with SGD_LOCUS:VMA6; SGD:S000004439 proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | contributes_to inferred by curator from GO:0033181" "compound eye pigmentation ; GO:0048072 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype vacuolar acidification ; GO:0007035 | inferred from mutant phenotype regulation of Notch signaling pathway ; GO:0008593 | inferred from mutant phenotype ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from electronic annotation with InterPro:IPR016727 ATP hydrolysis coupled proton transport ; GO:0015991 | inferred by curator from GO:0033181" "vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220 | inferred from sequence or structural similarity with SGD_LOCUS:VMA6; SGD:S000004439 plasma membrane ; GO:0005886 | inferred from direct assay plasma membrane proton-transporting V-type ATPase complex ; GO:0033181 | inferred from mutant phenotype" "cho, VhaAC39-1, CG2934, vhaAC39, anon-EST:GressD5, vhaAC39-1, VhaAC39, Vhaac39, ATP6V0D1, V0d" "IPR002843:ATPase, V0 complex, c/d subunit, IPR016727:ATPase, V0 complex, subunit d" CG2934 27-Aug-18 DroID_v2018_08 Drer\atp6v0d1 Scer\VMA6 Cele\vha-16 "Xtro\atp6v0d1, Xtro\atp6v0d2" "Mmus\Atp6v0d2, Mmus\Atp6v0d1" "Hsap\ATP6V0D2, Hsap\ATP6V0D1" "eye color defective,viable,fertile" "pigment cell,Malpighian tubule" FBgn0259972 Sfp77F Seminal fluid protein 77F http://flybase.org/reports/FBgn0259972 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "Sfp77F, CG42482" - CG42482 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265535 CG44385 - http://flybase.org/reports/FBgn0265535 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44385 - CG44385 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0087002 apolpp apolipophorin http://flybase.org/reports/FBgn0087002 protein_coding_gene heme binding ; GO:0020037 | inferred from direct assay lipid transporter activity ; GO:0005319 | inferred from direct assay fatty acid binding ; GO:0005504 | inferred from direct assay receptor binding ; GO:0005102 | inferred from physical interaction with ptc microtubule binding ; GO:0008017 | inferred from direct assay lipid transporter activity ; GO:0005319 | inferred from mutant phenotype retinol binding ; GO:0019841 | inferred from direct assay lipid transport ; GO:0006869 | inferred from direct assay Wnt signaling pathway ; GO:0016055 | inferred from mutant phenotype smoothened signaling pathway ; GO:0007224 | inferred from mutant phenotype transport ; GO:0006810 | traceable author statement lipid transport ; GO:0006869 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from direct assay endocytic vesicle ; GO:0030139 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay extracellular region ; GO:0005576 | non-traceable author statement lipid particle ; GO:0005811 | inferred from direct assay basal part of cell ; GO:0045178 | inferred from direct assay "RfaBp, RFABG, CG11064, ApoLII, ApoLI, T3, RfaBP, RFBP, DRBP, lipophorin, Lipophorin, Rfabg, Lpp, RFABP, rfabg, ApoL1, ApoL2, Rfabp, apolpp, apoLpp, chr4:1088013..1088173, apoLI, apoLII, apoLPP" "IPR015817:Vitellinogen, open beta-sheet, subdomain 1, IPR015819:Lipid transport protein, beta-sheet shell, IPR001747:Lipid transport protein, N-terminal, IPR001846:von Willebrand factor, type D domain, IPR009454:Lipid transport, open beta-sheet, IPR011030:Vitellinogen, superhelical, IPR015255:Vitellinogen, open beta-sheet, IPR015816:Vitellinogen, beta-sheet N-terminal" CG11064 27-Aug-18 DroID_v2018_08 "Drer\apobb.1, Drer\si:dkey-4c23.3, Drer\vtg1, Drer\vtg2, Drer\vtg6, Drer\vtg3, Drer\vtg4, Drer\apoba, Drer\vtg7" - "Cele\vit-2, Cele\vit-1" "Xtro\vtga2, Xtro\LOC100485054" Mmus\Apob "Hsap\APOB, Hsap\LOC400499" FBgn0263234 Phae1 Phaedra 1 http://flybase.org/reports/FBgn0263234 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "CG16996, Phae1, SP134" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site" CG16996 27-Aug-18 DroID_v2018_08 Drer\zmp:0000001088 - Cele\svh-1 - "Mmus\Klk1b3, Mmus\Prss53, Mmus\Prss36" "Hsap\PRSS36, Hsap\PRSS53" FBgn0266634 asRNA:CR45141 - http://flybase.org/reports/FBgn0266634 non_protein_coding_gene - - - CR45141 - CR45141 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0067861 Sdic1 Sperm-specific dynein intermediate chain 1 http://flybase.org/reports/FBgn0067861 protein_coding_gene molecular_function ; GO:0003674 | no biological data available microtubule-based movement ; GO:0007018 | inferred from electronic annotation with InterPro:IPR025956 cytoplasmic dynein complex ; GO:0005868 | inferred from electronic annotation with InterPro:IPR025956 sperm flagellum ; GO:0036126 | inferred from direct assay "CG9580, Sdic1, Sdic:CG9580" "IPR001680:WD40 repeat, IPR015943:WD40/YVTN repeat-like-containing domain, IPR017986:WD40-repeat-containing domain, IPR025956:Cytoplasmic dynein 1 intermediate chain 1/2" CG9580 27-Aug-18 DroID_v2018_08 "Drer\dync1i2b, Drer\LOC103908626, Drer\dync1i1, Drer\dnai1.1, Drer\dnai2a" "Scer\PFS2, Scer\PAC11" "Cele\dyci-1, Cele\prp-17" "Xtro\dync1i2, Xtro\dync1i1" "Mmus\Dync1i1, Mmus\Dync1i2, Mmus\Wdr63" "Hsap\DYNC1I1, Hsap\WDR60, Hsap\DYNC1I2" FBgn0265682 lncRNA:CR44489 - http://flybase.org/reports/FBgn0265682 non_protein_coding_gene - - - "lincRNA.183, CR44489" - CR44489 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0044385 Scim9 Sensitized chromosome inheritance modifier 9 http://flybase.org/reports/FBgn0044385 gene - female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype sister chromatid cohesion ; GO:0007062 | inferred from mutant phenotype - Scim9 - - 27-Aug-18 DroID_v2018_08 - - - - - - "meiotic cell cycle defective,dominant,partially lethal - majority die,recessive,mitotic cell cycle defective" "mitosis & nuclear chromosome,nuclear chromosome" FBgn0266911 asRNA:CR45371 - http://flybase.org/reports/FBgn0266911 non_protein_coding_gene - - - CR45371 - CR45371 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001433 l(1)air7 lethal aberrant immune response 7 http://flybase.org/reports/FBgn0001433 - gene - - - "air7, l(1)air[7], l(1)jnR3, RC61, jnR3, l(1)7Ac, l(1)air7" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,cell lethal,germline clone" FBgn0030186 CG2962 - http://flybase.org/reports/FBgn0030186 protein_coding_gene - - - CG2962 IPR031903:Domain of unknown function DUF4766 CG2962 27-Aug-18 DroID_v2018_08 Drer\pou2af1 - - - Mmus\Pou2af1 Hsap\POU2AF1 viable FBgn0011199 l(1)304-69 lethal (1) 304-69 http://flybase.org/reports/FBgn0011199 FBgn0010203 gene - - - "304-69, l(1)304-69" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0083299 E(smoDN)1824 Enhancer of smoDN 1824 http://flybase.org/reports/FBgn0083299 gene - - - E(smoDN)1824 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085307 CG34278 - http://flybase.org/reports/FBgn0085307 protein_coding_gene - - - CG34278 - CG34278 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0027332 l(1)G0013 lethal (1) G0013 http://flybase.org/reports/FBgn0027332 - gene - - - l(1)G0013 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0060811 l(3)S054515 lethal (3) S054515 http://flybase.org/reports/FBgn0060811 gene - - - "0545/15, l(3)S054515" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0052391 CG32391 - http://flybase.org/reports/FBgn0052391 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32391 - CG32391 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0003143 pra prawny abdomen http://flybase.org/reports/FBgn0003143 - gene - - - pra - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,viable,poor" "adult thorax,adult abdomen,wing" FBgn0002727 mfd myofibrillar defect http://flybase.org/reports/FBgn0002727 - gene - - - mfd - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0066317 29B70 29B70 http://flybase.org/reports/FBgn0066317 gene molecular_function ; GO:0003674 | no biological data available mushroom body development ; GO:0016319 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available 29B70 - - 27-Aug-18 DroID_v2018_08 - - - - - - "embryonic/larval mushroom body,somatic clone" FBgn0085764 CR40668 - http://flybase.org/reports/FBgn0085764 rRNA_gene - - - CR40668 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005444 l(1)v150 lethal (1) v150 http://flybase.org/reports/FBgn0005444 - gene - - - "l(1)150, l(1)v150" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0022302 l(1)L60.6 lethal (1) L60.6 http://flybase.org/reports/FBgn0022302 - gene - - - "L60.6, l(1)L60.6" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0058370 CG40370 - http://flybase.org/reports/FBgn0058370 protein_coding_gene - - - CG40370 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265690 lncRNA:CR44497 - http://flybase.org/reports/FBgn0265690 non_protein_coding_gene - - - "lincRNA.113, CR44497" - CR44497 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0082592 fiddler-crab fiddler-crab http://flybase.org/reports/FBgn0082592 gene - - - fiddler-crab - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0003748 Treh Trehalase http://flybase.org/reports/FBgn0003748 "FBgn0014436, FBgn0025313, FBgn0034584" protein_coding_gene "alpha,alpha-trehalase activity ; GO:0004555 | inferred from mutant phenotype trehalase activity ; GO:0015927 | inferred from mutant phenotype alpha,alpha-trehalase activity ; GO:0004555 | inferred from direct assay" neuronal stem cell population maintenance ; GO:0097150 | inferred from mutant phenotype trehalose catabolic process ; GO:0005993 | inferred from mutant phenotype trehalose metabolic process ; GO:0005991 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "TRE, 87D3T, Tre, TREH, anon-sts38, anon-EST:Posey159, ESTS:87D3T, CG9364, Treh, DmTre" "IPR018232:Glycoside hydrolase, family 37, conserved site, IPR001661:Glycoside hydrolase, family 37, IPR008928:Six-hairpin glycosidase-like" CG9364 27-Aug-18 DroID_v2018_08 Drer\treh "Scer\NTH2, Scer\NTH1" "Cele\tre-1, Cele\tre-4, Cele\tre-5, Cele\tre-3, Cele\tre-2" Xtro\treh Mmus\Treh Hsap\TREH "viable,fertile,visible,planar polarity defective,lethal - all die before end of pupal stage,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0032523 CG16956 - http://flybase.org/reports/FBgn0032523 protein_coding_gene - - - CG16956 - CG16956 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0082930 snoRNA:Me28S-G2703b snoRNA:Me28S-G2703b http://flybase.org/reports/FBgn0082930 snoRNA_gene - - - "snoRNA:Me28S-G2703b, Me28S-Gm2703b, CR34540" - CR34540 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0026342 Su(tor)2-113-31 Su(tor)2-113-31 http://flybase.org/reports/FBgn0026342 - gene - - - Su(tor)2-113-31 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037504 CG1142 - http://flybase.org/reports/FBgn0037504 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:24013 biological_process ; GO:0008150 | no biological data available nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:24013 CG1142 IPR014810:Fcf2 pre-rRNA processing CG1142 27-Aug-18 DroID_v2018_08 Drer\dnttip2 Scer\FCF2 Cele\Y49F6B.2 - Mmus\Dnttip2 Hsap\DNTTIP2 FBgn0025347 anon-11b anon-11b http://flybase.org/reports/FBgn0025347 - gene - - - anon-11b - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0087014 l(3)61Db-S lethal (3) 61Db of Saito http://flybase.org/reports/FBgn0087014 gene - - - "l(3)61Db-S, l(3)61Db" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0004168 5-HT1A 5-hydroxytryptamine (serotonin) receptor 1A http://flybase.org/reports/FBgn0004168 - protein_coding_gene G-protein coupled serotonin receptor activity ; GO:0004993 | traceable author statement Gi/o-coupled serotonin receptor activity ; GO:0001586 | non-traceable author statement G-protein coupled amine receptor activity ; GO:0008227 | inferred from sequence or structural similarity neurotransmitter receptor activity ; GO:0030594 | inferred from biological aspect of ancestor with PANTHER:PTN000664111 G-protein coupled serotonin receptor activity ; GO:0004993 | inferred from direct assay G-protein coupled serotonin receptor activity ; GO:0004993 | inferred from sequence or structural similarity "phospholipase C-activating serotonin receptor signaling pathway ; GO:0007208 | inferred from direct assay male courtship behavior ; GO:0008049 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype anesthesia-resistant memory ; GO:0007615 | inferred from direct assay adenylate cyclase-inhibiting serotonin receptor signaling pathway ; GO:0007198 | inferred from direct assay adenylate cyclase-inhibiting serotonin receptor signaling pathway ; GO:0007198 | traceable author statement serotonin receptor signaling pathway ; GO:0007210 | inferred from direct assay serotonin receptor signaling pathway ; GO:0007210 | inferred from sequence or structural similarity phospholipase C-activating serotonin receptor signaling pathway ; GO:0007208 | traceable author statement regulation of circadian sleep/wake cycle, sleep ; GO:0045187 | inferred from mutant phenotype" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR017452 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity" "CG16720, 5HT[[1ADro]], Dm5HTdro2A, 5HT-dro2A, 5-HT[[1ADro]], 5-HT-dro2A, DRO2A, 5htdro2a, 5-HT1ADro, 5HT1A, 5HT-drp[[2A]], 5HT-R2A, 5-HT1A, d5-HT1A, 5-HT[1A]Dro, 5-HT[[1A]], 5-HT[[1A]]DRO, HT1A, 5HT1a" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG16720 27-Aug-18 DroID_v2018_08 "Drer\or137-1, Drer\or137-5, Drer\si:dkeyp-3f10.11, Drer\htr5ab, Drer\or133-1, Drer\or137-8, Drer\or132-2, Drer\or137-2, Drer\or132-4, Drer\or132-3, Drer\or137-4, Drer\or137-3, Drer\or135-1, Drer\htr1d, Drer\or134-1, Drer\or132-5, Drer\htr1fb, Drer\htr1aa, Drer\si:dkeyp-3f10.12, Drer\si:dkeyp-3f10.14, Drer\htr1fa, Drer\htr5aa, Drer\si:dkey-92k1.9, Drer\htr1ab, Drer\or137-9, Drer\htr1e, Drer\or136-1, Drer\or132-1, Drer\or137-7, Drer\htr1b" - Cele\ser-4 "Xtro\htr5a, Xtro\htr1f, Xtro\htr1a" "Mmus\Htr5b, Mmus\Htr1d, Mmus\Htr1f, Mmus\Htr1a, Mmus\Htr1b, Mmus\Htr5a" "Hsap\HTR1F, Hsap\HTR1D, Hsap\HTR5A, Hsap\HTR1B, Hsap\HTR1E, Hsap\HTR1A" " embryonic stage | stage 16-17 , embryonic stage | stage 16,17 " " ventral midline

, embryonic central nervous system

, VUM neuron

" "starvation stress response defective,short lived,cold stress response defective,behavior defective,heat stress response defective,memory defective" FBgn0058045 CG40045 - http://flybase.org/reports/FBgn0058045 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:12482 ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with HGNC:12482 protein polyubiquitination ; GO:0000209 | inferred from biological aspect of ancestor with PANTHER:PTN000629793 ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from biological aspect of ancestor with PANTHER:PTN000629793 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 "BcDNA:RE63412, CG40045" "IPR000608:Ubiquitin-conjugating enzyme E2, IPR016135:Ubiquitin-conjugating enzyme/RWD-like, IPR023313:Ubiquitin-conjugating enzyme, active site" CG40045 27-Aug-18 DroID_v2018_08 "Drer\cdc34b, Drer\ube2r2, Drer\ube2g1b, Drer\ube2g1a, Drer\ube2g2, Drer\cdc34a" "Scer\CDC34, Scer\UBC7" "Cele\ubc-7, Cele\ubc-14" "Xtro\ube2g2, Xtro\ube2r2, Xtro\ube2g1, Xtro\cdc34" "Mmus\Ube2r2, Mmus\Ube2g1, Mmus\Ube2g2, Mmus\Cdc34" "Hsap\UBE2R2, Hsap\UBE2G1, Hsap\UBE2G2, Hsap\CDC34" DRSC21232 K -0.034833707 0.168078986 0.215030145 0.277643187 0.371501906 2.233570939 FBgn0261839 pre-mod(mdg4)-Y - http://flybase.org/reports/FBgn0261839 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "pre-mod(mdg4)-Y, CG42771, RY" "IPR007588:Zinc finger, FLYWCH-type" CG42771 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0050155 tRNA:Trp-CCA-1-1 transfer RNA:Tryptophan-CCA 1-1 http://flybase.org/reports/FBgn0050155 tRNA_gene UGG codon-amino acid adaptor activity ; GO:0033416 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033416 cytosol ; GO:0005829 | inferred by curator from GO:0033416 "AE002787.trna60-TrpCCA, tRNA:W:CCA:AE002787-c, CR30155, chr2R.trna44-TrpCCA, tRNA-Trp-CCA-1-1, tRNA:Trp-CCA-1-1, tRNA:CR30155, UGG" - CR30155 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034986 mRpS17 mitochondrial ribosomal protein S17 http://flybase.org/reports/FBgn0034986 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:Q9Y2R5 structural constituent of ribosome ; GO:0003735 | traceable author statement mitochondrial translation ; GO:0032543 | inferred from sequence or structural similarity with UniProtKB:Q9Y2R5 translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:Q9Y2R5 mitochondrial translation ; GO:0032543 | traceable author statement mitochondrial small ribosomal subunit ; GO:0005763 | traceable author statement mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with UniProtKB:Q9Y2R5 "MRP-S17, CG4326, mRpS17" "IPR012340:Nucleic acid-binding, OB-fold, IPR000266:Ribosomal protein S17/S11" CG4326 27-Aug-18 DroID_v2018_08 Drer\mrps17 - Cele\mrps-17 Xtro\mrps17 Mmus\Mrps17 Hsap\MRPS17 viable DRSC04463 E -1.234529304 0.007542804 -1.769462037 0.157535672 0.1234868 0.917702378 FBgn0043527 anon-AE003814.3 anon-AE003814.3 http://flybase.org/reports/FBgn0043527 gene - - - anon-AE003814.3 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0015302 Su(SD)3A Suppressor of SD 3A http://flybase.org/reports/FBgn0015302 - gene - - - Su(SD)3A - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0261452 scaRNA:MeU2-G25 small Cajal body-specific RNA : MeU2-G25 http://flybase.org/reports/FBgn0261452 snoRNA_gene - - Cajal body ; GO:0015030 | inferred from direct assay "mgU2-25, scaRNA:mask-a, scaRNA:mgU2-25, scaRNA:MeU2-G25" - CR43569 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0011642 Zyx Zyxin http://flybase.org/reports/FBgn0011642 "FBgn0047225, FBgn0052018" protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781 protein binding ; GO:0005515 | inferred from physical interaction with ena "cell adhesion ; GO:0007155 | inferred from sequence or structural similarity with HGNC:13200 terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype positive regulation of imaginal disc growth ; GO:0045572 | inferred from mutant phenotype liquid clearance, open tracheal system ; GO:0035002 | inferred from mutant phenotype chitin-based cuticle sclerotization ; GO:0007593 | inferred from mutant phenotype hippo signaling ; GO:0035329 | inferred from mutant phenotype imaginal disc-derived wing expansion ; GO:0048526 | inferred from mutant phenotype positive regulation of organ growth ; GO:0046622 | inferred from mutant phenotype positive regulation of eclosion ; GO:0045805 | inferred from mutant phenotype" cytoskeleton ; GO:0005856 | inferred from sequence or structural similarity stress fiber ; GO:0001725 | inferred from direct assay cell-cell junction ; GO:0005911 | inferred from sequence or structural similarity with HGNC:13200 focal adhesion ; GO:0005925 | inferred from sequence or structural similarity with HGNC:13200 subapical complex ; GO:0035003 | inferred from direct assay "CG32018, BcDNA:LD06023, zyx102, zyxin, ZYX102, lim, Zyxin, Zyx102, DmLIM-1, Lim102EF, DLim-1, Zyx102EF, Zyx, zyx" "IPR001781:Zinc finger, LIM-type" CG32018 27-Aug-18 DroID_v2018_08 "Drer\trip6, Drer\limd1b, Drer\ajuba, Drer\wtip, Drer\lpp, Drer\fblim1, Drer\zyx, Drer\limd1a" Scer\LRG1 Cele\zyx-1 Xtro\lpp "Mmus\Limd1, Mmus\Trip6, Mmus\Wtip, Mmus\Zyx, Mmus\Fblim1, Mmus\Lpp, Mmus\Ajuba" "Hsap\ZYX, Hsap\TRIP6, Hsap\WTIP, Hsap\LPP, Hsap\FBLIM1, Hsap\LIMD1, Hsap\AJUBA" "viable,locomotor behavior defective,eclosion defective,lethal - all die before end of P-stage,some die during pharate adult stage,fertile,size defective" "wing,adult abdomen,adult cuticle,adult trachea,tracheole,crossvein,ectopic" FBgn0033307 CG14752 - http://flybase.org/reports/FBgn0033307 protein_coding_gene - - - CG14752 - CG14752 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0051395 CG31395 - http://flybase.org/reports/FBgn0051395 protein_coding_gene - - - CG31395 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040690 CG13899 - http://flybase.org/reports/FBgn0040690 protein_coding_gene - - - CG13899 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0015025 CkIIalpha-i1 CKII-alpha subunit interactor-1 http://flybase.org/reports/FBgn0015025 - protein_coding_gene "nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 protein kinase binding ; GO:0019901 | inferred from physical interaction with CkIIα RNA polymerase II transcription factor activity, sequence-specific DNA binding ; GO:0000981 | inferred from biological aspect of ancestor with PANTHER:PTN000003381" transcription from RNA polymerase II promoter ; GO:0006366 | inferred from electronic annotation with InterPro:IPR027755 nucleus ; GO:0005634 | inferred from sequence model nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000003381 "CKIIalpha-I1, CkIIalpha-i1, CG6215, dCKIIalpha-i1, ZFP47, DmA35, CKIIalpha-iI" "IPR013087:Zinc finger C2H2-type, IPR027755:Transcription factor Ovo-like, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR027775:C2H2- zinc finger protein family subset" CG6215 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-229b18.3, Drer\si:dkey-66i24.9, Drer\zbtb11, Drer\znf131, Drer\si:dkey-17e16.13, Drer\zgc:171929, Drer\ovol1" Scer\RPN4 "Cele\Y5F2A.4, Cele\M03D4.4, Cele\ztf-2, Cele\Y111B2A.10, Cele\lin-48, Cele\Y55F3AM.14" Xtro\zbtb11 "Mmus\Zfp131, Mmus\Ovol1, Mmus\Rest, Mmus\Zfp770, Mmus\Rpl24, Mmus\Ovol3, Mmus\Ovol2" "Hsap\OVOL3, Hsap\ZNF131, Hsap\OVOL2, Hsap\ZNF770, Hsap\REST, Hsap\ZBTB11, Hsap\OVOL1" viable FBgn0264474 lncRNA:CR43882 - http://flybase.org/reports/FBgn0264474 non_protein_coding_gene - - - CR43882 - CR43882 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259699 CG42353 - http://flybase.org/reports/FBgn0259699 protein_coding_gene - - - "CG42353, CG9216" - CG42353 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" FBgn0031549 Spindly Spindly http://flybase.org/reports/FBgn0031549 protein_coding_gene protein phosphatase 1 binding ; GO:0008157 | inferred from physical interaction with flw inferred from physical interaction with Pp1-13C inferred from physical interaction with Pp1α-96A inferred from physical interaction with Pp1-87B regulation of mitotic metaphase/anaphase transition ; GO:0030071 | inferred from mutant phenotype microtubule ; GO:0005874 | inferred from direct assay kinetochore ; GO:0000776 | inferred from direct assay "CG15415, Spindly" - CG15415 27-Aug-18 DroID_v2018_08 Drer\zgc:171223 - - Xtro\spdl1 Mmus\Spdl1 Hsap\SPDL1 DRSC00430 IE -0.053291631 -2.131649703 1.474836741 -4.287608382 -0.04942602 -0.959051599 FBgn0015931 dsRNABP5 ds-RNA binding protein 5 http://flybase.org/reports/FBgn0015931 - gene - - - "dsRNABP#5, dsRNABP5" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262575 CG43115 - http://flybase.org/reports/FBgn0262575 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43115 IPR032145:Protein of unknown function DUF4818 CG43115 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0022090 l(2)k07312b lethal (2) k07312b http://flybase.org/reports/FBgn0022090 - gene - - - l(2)k07312b - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0266435 CG45065 - http://flybase.org/reports/FBgn0266435 protein_coding_gene "flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR012132 oxidoreductase activity, acting on CH-OH group of donors ; GO:0016614 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR007867, InterPro:IPR012132 oxidoreductase activity ; GO:0016491 | inferred from sequence or structural similarity with Eo" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000172, InterPro:IPR007867, InterPro:IPR012132, InterPro:IPR023753 ecdysteroid metabolic process ; GO:0045455 | inferred from sequence or structural similarity with Eo inferred from genomic context with Eo" cellular_component ; GO:0005575 | no biological data available "CG45065, CG9517, Dm GMCepsilon1" "IPR012132:Glucose-methanol-choline oxidoreductase, IPR007867:Glucose-methanol-choline oxidoreductase, C-terminal, IPR000172:Glucose-methanol-choline oxidoreductase, N-terminal, IPR023753:FAD/NAD(P)-binding domain" CG45065 27-Aug-18 DroID_v2018_08 Drer\chdh - Cele\C34C6.4 - Mmus\Chdh Hsap\CHDH viable FBgn0062708 EP1020 EP1020 http://flybase.org/reports/FBgn0062708 gene - - - "EP(2)1020, EP1020" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031564 CG2816 - http://flybase.org/reports/FBgn0031564 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 - - CG2816 "IPR002223:Pancreatic trypsin inhibitor Kunitz domain, IPR020901:Proteinase inhibitor I2, Kunitz, conserved site" CG2816 27-Aug-18 DroID_v2018_08 "Drer\tfpia, Drer\tfpi2, Drer\spint2, Drer\col6a4a, Drer\spint1a, Drer\spint1b, Drer\ambp, Drer\si:dkeyp-73b11.8, Drer\si:dkey-117n7.5" - "Cele\mec-9, Cele\mec-1, Cele\T21D12.7" "Xtro\spint2, Xtro\ambp, Xtro\tfpi2, Xtro\spint1" "Mmus\Wfdc6a, Mmus\Spint3, Mmus\Wfdc8, Mmus\Tfpi, Mmus\Spint4, Mmus\Wfdc6b, Mmus\Eppin, Mmus\Spint5, Mmus\Ambp, Mmus\Tfpi2, Mmus\Spint2, Mmus\Spint1" "Hsap\TFPI, Hsap\WFIKKN1, Hsap\WFDC6, Hsap\SPINT3, Hsap\SPINT2, Hsap\SPINT4, Hsap\WFDC8, Hsap\AMBP, Hsap\EPPIN-WFDC6, Hsap\SPINT1, Hsap\TFPI2" viable FBgn0051721 Trim9 Tripartite motif containing 9 http://flybase.org/reports/FBgn0051721 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000315, InterPro:IPR001841 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:16288 zinc ion binding ; GO:0008270 | inferred from sequence model" axonogenesis ; GO:0007409 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from sequence or structural similarity with HGNC:16288 netrin-activated signaling pathway ; GO:0038007 | inferred from genetic interaction with fra inferred from physical interaction with fra inferred from physical interaction with pico axon midline choice point recognition ; GO:0016199 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype "intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR000315, InterPro:IPR003649 cellular_component ; GO:0005575 | no biological data available" "CG31721, CG6256, CG13145, Trim9, Asap, asap, dTrim9" "IPR013320:Concanavalin A-like lectin/glucanase domain, IPR000315:B-box-type zinc finger, IPR001841:Zinc finger, RING-type, IPR001870:B30.2/SPRY domain, IPR003649:B-box, C-terminal, IPR003877:SPRY domain, IPR003961:Fibronectin type III, IPR017903:COS domain, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013783:Immunoglobulin-like fold" CG31721 27-Aug-18 DroID_v2018_08 "Drer\btr06, Drer\trim35-24, Drer\fsd1l, Drer\trim8b, Drer\ftr82, Drer\trim35-36, Drer\trim62, Drer\trim35-13, Drer\trim35-25, Drer\trim35-28, Drer\trim35-39, Drer\LOC558300, Drer\zgc:172170, Drer\zgc:92594, Drer\trim101, Drer\trim55a, Drer\btr22, Drer\trim3b, Drer\trim59, Drer\trim35-19, Drer\trim13, Drer\trim35-23, Drer\ftr56, Drer\ftr73, Drer\trim35-31, Drer\trim65, Drer\btr12, Drer\trim35-10, Drer\trim35-29, Drer\trim63a, Drer\si:ch211-12p12.2, Drer\mid2, Drer\trim9, Drer\trim35-3, Drer\trim35-21, Drer\trim63b, Drer\trim46b, Drer\trim109, Drer\ftr83, Drer\btr09, Drer\ftr41, Drer\ftr14, Drer\trim35-35, Drer\ftr24, Drer\ftr84, Drer\si:ch73-106l15.2, Drer\ftr43, Drer\trim35-34, Drer\fsd1, Drer\trim47, Drer\trim46a, Drer\ftr72, Drer\si:ch211-175l6.2, Drer\si:ch211-276c2.4, Drer\cmya5, Drer\btr20, Drer\trim8a, Drer\trim54, Drer\trim25, Drer\trim67, Drer\si:ch73-166o21.1, Drer\trim35-22, Drer\LOC100006839, Drer\ftr70, Drer\btr33, Drer\trim3a, Drer\trim55b, Drer\trim2a, Drer\trim36, Drer\mid1, Drer\zgc:173581, Drer\si:dkey-46i9.6, Drer\si:ch211-216p19.6, Drer\bty, Drer\trim35-20, Drer\btr29, Drer\zgc:136302" - Cele\madd-2 "Xtro\trim55, Xtro\trim9, Xtro\fsd1l, Xtro\trim13, Xtro\trim67, Xtro\mid1, Xtro\trim36, Xtro\trim63" "Mmus\Trim12c, Mmus\Trim9, Mmus\Trim54, Mmus\Trim8, Mmus\Trim69, Mmus\Trim50, Mmus\Mid2, Mmus\Trim17, Mmus\Trim14, Mmus\Trim80, Mmus\Trim67, Mmus\Trim75, Mmus\Trim42, Mmus\Trim36, Mmus\Trim16, Mmus\Trim59, Mmus\Trim13, Mmus\Trim38, Mmus\Fsd2, Mmus\Fsd1l, Mmus\Trim3, Mmus\Trim55, Mmus\Mid1, Mmus\Trim43b, Mmus\Trim43c, Mmus\Trim30a, Mmus\Trim25, Mmus\Trim2, Mmus\Trim56, Mmus\Trim62, Mmus\Trim31, Mmus\Trim46, Mmus\Trim43a, Mmus\Fsd1, Mmus\Trim63" "Hsap\TRIM14, Hsap\TRIM3, Hsap\TRIM62, Hsap\TRIM13, Hsap\FSD1, Hsap\TRIM5, Hsap\TRIM22, Hsap\MID2, Hsap\TRIM56, Hsap\TRIM31, Hsap\TRIM50, Hsap\TRIM38, Hsap\TRIM63, Hsap\FSD2, Hsap\TRIM2, Hsap\TRIM54, Hsap\TRIM10, Hsap\TRIM59, Hsap\FSD1L, Hsap\TRIM55, Hsap\TRIM27, Hsap\TRIM46, Hsap\TRIM8, Hsap\TRIM69, Hsap\TRIM60, Hsap\TRIM42, Hsap\TRIM67, Hsap\TRIM9, Hsap\MID1, Hsap\TRIM17, Hsap\TRIM25, Hsap\TRIM36" "neuroanatomy defective,viable,fertile,locomotor behavior defective,somatic clone,lethal,visible" "ventral nerve cord commissure,class IV dendritic arborizing neuron,wing,dopaminergic neuron,midline crossing tract,ventral multidendritic neuron vdaB,dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa,somatic clone | third instar larval stage,ectopic,ganglion mother cell,trichogen cell" DRSC02242 E 0.144096503 -0.063856244 -1.89865789 0.494458012 -0.111217673 -0.770306922 FBgn0016925 run::Hsap\RUNX1 run::Hsap\RUNX1 http://flybase.org/reports/FBgn0016925 - engineered_fusion_gene - - - "run::Hsap\AML1, run::Hsap\RUNX1, run::Hsap\CBFA2" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0026377 RalBp-like Retinal-binding protein like http://flybase.org/reports/FBgn0026377 - gene retinoid binding ; GO:0005501 | inferred from sequence or structural similarity - cytoplasm ; GO:0005737 | inferred from direct assay RalBp-like - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0063397 Stalker2\ORF2 Stalker2 element ORF2 http://flybase.org/reports/FBgn0063397 transposable_element_gene - - - "rom\ORF2, Stalker2\ORF2" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085427 CG34398 - http://flybase.org/reports/FBgn0085427 protein_coding_gene - - - "CG34398, CG15867, CG9487" - CG34398 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible" "anterior crossvein,wing" FBgn0261995 CG42813 - http://flybase.org/reports/FBgn0261995 protein_coding_gene "hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides ; GO:0016818 | inferred from electronic annotation with InterPro:IPR004385 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR004385" - - "CG42813, Nudix, CG31063, CG6001" "IPR015797:NUDIX hydrolase domain-like, IPR004385:Nucleoside diphosphate pyrophosphatase, IPR000086:NUDIX hydrolase domain" CG42813 27-Aug-18 DroID_v2018_08 "Drer\nudt5, Drer\nudt14" Scer\YSA1 "Cele\ndx-2, Cele\C50F4.16" Xtro\nudt5 "Mmus\Nudt5, Mmus\Nudt14" "Hsap\NUDT14, Hsap\NUDT5" FBgn0035734 CG14823 - http://flybase.org/reports/FBgn0035734 protein_coding_gene lysozyme activity ; GO:0003796 | inferred from electronic annotation with InterPro:IPR008597 - - CG14823 IPR008597:Destabilase CG14823 27-Aug-18 DroID_v2018_08 - - "Cele\ilys-1, Cele\ilys-2, Cele\ilys-5, Cele\ilys-4, Cele\ilys-3, Cele\ilys-6" - - - FBgn0040045 CR12460 - http://flybase.org/reports/FBgn0040045 pseudogene_attribute - - - "CG40051, CG12460, CR12460" - CR12460 27-Aug-18 DroID_v2018_08 - - - - - - DRSC20970 I 2.040637879 1.564803824 0.689333008 1.191313271 0.460100374 0.36200166 FBgn0265448 lncRNA:CR44348 - http://flybase.org/reports/FBgn0265448 non_protein_coding_gene - - - CR44348 - CR44348 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031683 CG4230 - http://flybase.org/reports/FBgn0031683 protein_coding_gene - - - CG4230 - CG4230 27-Aug-18 DroID_v2018_08 Drer\hax1 - - - Mmus\Hax1 Hsap\HAX1 viable FBgn0051563 CG31563 - http://flybase.org/reports/FBgn0051563 protein_coding_gene - - - CG31563 - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,lethal - all die before end of pupal stage,some die during pupal stage" DRSC21338 K -1.382546749 1.27048122 -0.867556727 -0.129577522 -0.757207174 -1.692280197 FBgn0039083 CG10177 - http://flybase.org/reports/FBgn0039083 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719 protein serine/threonine kinase activity ; GO:0004674 | inferred from biological aspect of ancestor with PANTHER:PTN000680267 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement protein phosphorylation ; GO:0006468 | non-traceable author statement regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype signal transduction involved in mitotic DNA damage checkpoint ; GO:1902402 | inferred from biological aspect of ancestor with PANTHER:PTN002389494 Golgi organization ; GO:0007030 | inferred from mutant phenotype peptidyl-threonine phosphorylation ; GO:0018107 | inferred from biological aspect of ancestor with PANTHER:PTN000680267 peptidyl-serine phosphorylation ; GO:0018105 | inferred from biological aspect of ancestor with PANTHER:PTN000680267 mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from biological aspect of ancestor with PANTHER:PTN002389494 negative regulation of cell size ; GO:0045792 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN002389494 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN002389494 CG10177 "IPR000719:Protein kinase domain, IPR003533:Doublecortin domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain" CG10177 27-Aug-18 DroID_v2018_08 "Drer\LOC100334396, Drer\trioa, Drer\camk1a, Drer\mylk4a, Drer\mylk3, Drer\triob, Drer\camk1b, Drer\dapk1, Drer\zgc:153952, Drer\si:ch211-27e6.1, Drer\chek1, Drer\stk17a, Drer\LOC101886687, Drer\mylk4b, Drer\camkva, Drer\uhmk1, Drer\camkvb, Drer\dapk3, Drer\capsla, Drer\camkvl, Drer\spegb, Drer\dclk2a, Drer\si:dkey-240h12.4, Drer\capslb, Drer\stk17b, Drer\dapk2a, Drer\dapk2b, Drer\camk1gb, Drer\camk4, Drer\camk1db, Drer\si:ch73-60h1.1, Drer\pskh1, Drer\camk1da, Drer\stk33, Drer\pnck, Drer\camk1ga, Drer\ttnb" "Scer\RCK2, Scer\TDA1, Scer\RCK1, Scer\CMK2, Scer\CMK1, Scer\MEK1, Scer\IRE1, Scer\IKS1, Scer\CHK1" "Cele\zyg-8, Cele\R02C2.1, Cele\zyg-1, Cele\T07F12.4" "Xtro\caps, Xtro\trio, Xtro\stk17a, Xtro\dapk3, Xtro\pskh1, Xtro\dclk2, Xtro\dapk1, Xtro\camk4, Xtro\mylk4, Xtro\pnck, Xtro\kalrn, Xtro\mylk3, Xtro\dcx, Xtro\camk1g, Xtro\pskh2, Xtro\camk1d, Xtro\capsl, Xtro\camkv, Xtro\dapk2, Xtro\camk1, Xtro\stk33" "Mmus\Mylk2, Mmus\Stk17b, Mmus\Camk4, Mmus\Dclk1, Mmus\Caps2, Mmus\Camk1g, Mmus\Obscn, Mmus\Speg, Mmus\Camk1, Mmus\Dapk1, Mmus\Capsl, Mmus\Stk33, Mmus\Dclk2, Mmus\Pnck, Mmus\Mylk4, Mmus\Pskh1, Mmus\Camk1d, Mmus\Trio, Mmus\Dapk3, Mmus\Uhmk1, Mmus\Dapk2, Mmus\Camkv, Mmus\Mylk3, Mmus\Dcx" "Hsap\DCLK1, Hsap\DAPK2, Hsap\OBSCN, Hsap\DAPK1, Hsap\MYLK3, Hsap\MYLK2, Hsap\CAMK1, Hsap\SPEG, Hsap\CAPS2, Hsap\DAPK3, Hsap\DCLK2, Hsap\CAPS, Hsap\STK17A, Hsap\UHMK1, Hsap\CAPSL, Hsap\CAMK1D, Hsap\PNCK, Hsap\CAMKV, Hsap\MYLK4, Hsap\STK17B, Hsap\PSKH2, Hsap\CAMK4, Hsap\STK33, Hsap\CAMK1G, Hsap\DCX, Hsap\TRIO, Hsap\PSKH1" "viable,visible" "trichogen cell,mesothoracic tergum" FBgn0003298 rud ruddle http://flybase.org/reports/FBgn0003298 - gene - - - rud - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,good,fertile,visible,recessive,eye color defective" pigment cell FBgn0065402 l(2)SH1602 lethal (2) SH1602 http://flybase.org/reports/FBgn0065402 gene - - - "l(2)SH1602, l(2)SH2 1602" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0082909 60-16 60-16 http://flybase.org/reports/FBgn0082909 gene - - - 60-16 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0023114 anon-10At anon-10At http://flybase.org/reports/FBgn0023114 - gene - - - "13, anon-10At" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0028126 l(3)S057809a lethal (3) S057809a http://flybase.org/reports/FBgn0028126 gene - - - "0578/09, l(3)S057809, l(3)S057809a, l(3)s057809" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0085528 CG40862 - http://flybase.org/reports/FBgn0085528 protein_coding_gene - - - CG40862 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259664 B0751 - http://flybase.org/reports/FBgn0259664 gene - - - B0751 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "submarginal cell,wing" FBgn0085834 CR42217 - http://flybase.org/reports/FBgn0085834 non_protein_coding_gene - - - CR42217 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259320 EP-M - http://flybase.org/reports/FBgn0259320 gene - - - EP-M - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing vein,wing margin" FBgn0016767 anon-17Cd anon-17Cd http://flybase.org/reports/FBgn0016767 - gene - - - "C4, anon-17Cd" - - 27-Aug-18 DroID_v2018_08 - - - - - - " adult stage | female , embryonic stage | early " FBgn0044115 E(rst)C14 E(rst)C14 http://flybase.org/reports/FBgn0044115 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "C14, E(rst)C14" - - 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0259366 EP-634.2 - http://flybase.org/reports/FBgn0259366 gene - - - EP-634.2 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing hair,wing margin,wing vein,chaeta" FBgn0002516 l(3)Sp10 lethal (3) Sp10 http://flybase.org/reports/FBgn0002516 - gene - - - l(3)Sp10 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0259373 EP-284 - http://flybase.org/reports/FBgn0259373 gene - - - EP-284 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing vein,wing" FBgn0036594 CG13047 - http://flybase.org/reports/FBgn0036594 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - CG13047 - CG13047 27-Aug-18 DroID_v2018_08 - - Cele\T06E4.12 - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0011993 tRNA:Thr-AGT-1-5 transfer RNA:Threonine-AGT 1-5 http://flybase.org/reports/FBgn0011993 "FBgn0003833, FBgn0051589, FBgn0060045" tRNA_gene ACU codon-amino acid adaptor activity ; GO:0033437 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033437 cytosol ; GO:0005829 | inferred by curator from GO:0033437 "AE002708.trna49-ThrAGT, tRNA:T:AGT:AE002708-d, tRNA:thr:90Ca, CR31589, tRNA[[Thr]], chr3R.trna55-ThrAGT, tRNA-Thr-AGT-1-5, tRNA:Thr-AGT-1-5, tRNA:T:90Ca, ACU" - CR31589 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065489 l(2)SH1238 lethal (2) SH1238 http://flybase.org/reports/FBgn0065489 gene - - - "l(2)SH1238, l(2)SH2 1238" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0039451 CG6420 - http://flybase.org/reports/FBgn0039451 protein_coding_gene molecular_function ; GO:0003674 | no biological data available protein deubiquitination ; GO:0016579 | inferred from biological aspect of ancestor with PANTHER:PTN000364080 cellular_component ; GO:0005575 | no biological data available CG6420 "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG6420 27-Aug-18 DroID_v2018_08 "Drer\zmp:0000000529, Drer\wdr20" - Cele\wdr-20 Xtro\wdr20 "Mmus\Wdr20, Mmus\Dmwd, Mmus\Wdr20rt" "Hsap\WDR20, Hsap\DMWD" "viable,fertile" DRSC16035 K -0.39426711 0.241122906 -0.656145642 0.678835876 2.117854079 0.720366585 FBgn0012041 Atn Allatotropin http://flybase.org/reports/FBgn0012041 - gene hormone activity ; GO:0005179 | non-traceable author statement - - Atn - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051211 CG31211 - http://flybase.org/reports/FBgn0051211 protein_coding_gene - - - "CG14732, CG18546, cDNA, anon-WO03070958.3, CG31211" IPR031937:PNN-interacting serine/arginine-rich protein CG31211 27-Aug-18 DroID_v2018_08 Drer\pnisr - Cele\rsy-1 Xtro\pnisr Mmus\Pnisr Hsap\PNISR viable FBgn0030475 CG15748 - http://flybase.org/reports/FBgn0030475 protein_coding_gene - - - CG15748 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001446 l(1)7Ch lethal (1) 7Ch http://flybase.org/reports/FBgn0001446 - gene - - - l(1)7Ch - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0267508 28SrRNA-Psi:CR45848 28S ribosomal RNA pseudogene:CR45848 http://flybase.org/reports/FBgn0267508 pseudogene_attribute - - - "28SrRNA-Psi:CR45848, CR45848" - CR45848 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0082959 snoRNA:Psi28S-3405b snoRNA:Psi28S-3405b http://flybase.org/reports/FBgn0082959 snoRNA_gene - - - "snoRNA:Psi28S-3405b, psi28s-3405b, CR34620" - CR34620 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0052250 PMP34 Peroxisomal Membrane Protein 34 http://flybase.org/reports/FBgn0052250 protein_coding_gene FMN transmembrane transporter activity ; GO:0044610 | inferred from biological aspect of ancestor with PANTHER:PTN001942724 AMP transmembrane transporter activity ; GO:0080122 | inferred from biological aspect of ancestor with PANTHER:PTN001942724 ATP transmembrane transporter activity ; GO:0005347 | inferred from biological aspect of ancestor with PANTHER:PTN001942724 FAD transmembrane transporter activity ; GO:0015230 | inferred from biological aspect of ancestor with PANTHER:PTN001942724 NAD transporter activity ; GO:0051724 | inferred from biological aspect of ancestor with PANTHER:PTN001942724 coenzyme A transmembrane transporter activity ; GO:0015228 | inferred from biological aspect of ancestor with PANTHER:PTN001942724 ADP transmembrane transporter activity ; GO:0015217 | inferred from biological aspect of ancestor with PANTHER:PTN001942724 mitochondrial transport ; GO:0006839 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 nucleoside transport ; GO:0015858 | inferred from biological aspect of ancestor with PANTHER:PTN001942724 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 peroxisomal membrane ; GO:0005778 | inferred from sequence or structural similarity with HGNC:10987 integral component of peroxisomal membrane ; GO:0005779 | inferred from biological aspect of ancestor with PANTHER:PTN001942724 "CG1326, BcDNA:RE36975, PMP34, dPMP34, CG32250" "IPR018108:Mitochondrial substrate/solute carrier, IPR023395:Mitochondrial carrier domain" CG32250 27-Aug-18 DroID_v2018_08 "Drer\LOC566378, Drer\slc25a17" "Scer\YEA6, Scer\ANT1, Scer\YIA6" - Xtro\slc25a17 Mmus\Slc25a17 Hsap\SLC25A17 viable FBgn0001189 hfw halfway http://flybase.org/reports/FBgn0001189 FBgn0023532 protein_coding_gene molecular_function ; GO:0003674 | no biological data available response to ecdysone ; GO:0035075 | inferred from mutant phenotype intracellular signal transduction ; GO:0035556 | inferred from mutant phenotype pupariation ; GO:0035073 | inferred from mutant phenotype - "swi, CG3095, EG:171E4.2, SWI, CT10406, l(1)nfw, l(1)2Bf, hfw" "IPR032675:Leucine-rich repeat domain, L domain-like, IPR001611:Leucine-rich repeat" CG3095 27-Aug-18 DroID_v2018_08 "Drer\aspn, Drer\si:ch211-237i5.4" - "Cele\lron-2, Cele\slt-1, Cele\lron-1" "Xtro\vasn, Xtro\islr2" "Mmus\Aspn, Mmus\Islr2" Hsap\ISLR2 "viable,reduced,visible,recessive,lethal,male,lethal - all die before end of pupal stage,some die during pupal stage" "wing,adult abdomen" FBgn0024860 l(3)96Bb lethal (3) 96Bb http://flybase.org/reports/FBgn0024860 - gene - - - l(3)96Bb - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0034643 CG10321 - http://flybase.org/reports/FBgn0034643 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 DNA binding ; GO:0003677 | inferred from direct assay - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG10321 "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type" CG10321 27-Aug-18 DroID_v2018_08 "Drer\znf827, Drer\znf513, Drer\zbtb40" Scer\AZF1 Cele\klf-3 Xtro\zbtb40 "Mmus\Zfp827, Mmus\Zbtb40, Mmus\Zfp513" "Hsap\ZBTB40, Hsap\ZNF841, Hsap\ZNF836, Hsap\ZNF827, Hsap\ZNF513, Hsap\OSR2" viable FBgn0021811 l(2)k16525 lethal (2) k16525 http://flybase.org/reports/FBgn0021811 - gene - - - l(2)k16525 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0039210 CG13625 - http://flybase.org/reports/FBgn0039210 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:28199 "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071013" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "anon-WO0118547.376, CG13625" IPR018609:Bud13 CG13625 27-Aug-18 DroID_v2018_08 "Drer\si:dkeyp-69c1.6, Drer\casc3" Scer\BUD13 Cele\R08D7.1 "Xtro\bud13, Xtro\casc3" "Mmus\Bud13, Mmus\Casc3" "Hsap\BUD13, Hsap\CASC3" FBgn0005172 l(2)G583 lethal (2) G583 http://flybase.org/reports/FBgn0005172 - gene - - - l(2)G583 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0037018 CG4042 - http://flybase.org/reports/FBgn0037018 protein_coding_gene - - - CG4042 "IPR032675:Leucine-rich repeat domain, L domain-like" CG4042 27-Aug-18 DroID_v2018_08 Drer\si:ch1073-228b5.2 - "Cele\Y53G8AR.8, Cele\C05C8.1" "Xtro\atp5s, Xtro\atp5sl" "Mmus\Atp5sl, Mmus\Atp5s" "Hsap\ATP5SL, Hsap\ATP5S" viable FBgn0032312 CG14071 - http://flybase.org/reports/FBgn0032312 protein_coding_gene molecular_function ; GO:0003674 | no biological data available regulation of cell cycle ; GO:0051726 | inferred from direct assay cellular_component ; GO:0005575 | no biological data available CG14071 - CG14071 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0069242 eca eclair http://flybase.org/reports/FBgn0069242 protein_coding_gene transporter activity ; GO:0005215 | inferred from sequence model positive regulation of Wnt protein secretion ; GO:0061357 | inferred from mutant phenotype lipid particle organization ; GO:0034389 | inferred from mutant phenotype Golgi vesicle transport ; GO:0048193 | inferred from sequence model Golgi organization ; GO:0007030 | inferred from mutant phenotype ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from mutant phenotype positive regulation of protein exit from endoplasmic reticulum ; GO:0070863 | inferred from mutant phenotype positive regulation of canonical Wnt signaling pathway ; GO:0090263 | inferred from mutant phenotype dorsal/ventral pattern formation ; GO:0009953 | inferred from mutant phenotype regulation of post-mating oviposition ; GO:0048042 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype reproduction ; GO:0000003 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR009038 integral component of membrane ; GO:0016021 | inferred from sequence model endomembrane system ; GO:0012505 | inferred from direct assay "CG33104, CG9443, eca, ECA, p24, Eca" "IPR009038:GOLD domain, IPR015720:TMP21-related" CG33104 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-255i20.3, Drer\tmed9, Drer\tmed4" "Scer\ERP5, Scer\ERP1, Scer\ERP6" "Cele\T08D2.1, Cele\Y60A3A.9" "Xtro\tmed4, Xtro\tmed9" "Mmus\Tmed9, Mmus\Tmed11, Mmus\Tmed4" "Hsap\TMED9, Hsap\TMED4" "behavior defective,recessive,viable,fertile,lethal,maternal effect,female sterile,male semi-sterile,germline clone,partially lethal - majority die,non-rescuable maternal effect,female semi-sterile" "embryonic/first instar larval cuticle,dorsal,germline clone,wing vein,ectopic,wing margin,somatic clone" FBgn0000501 dsp dispersed http://flybase.org/reports/FBgn0000501 - gene molecular_function ; GO:0003674 | no biological data available Malpighian tubule morphogenesis ; GO:0007443 | inferred from mutant phenotype embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "dsp, Dsp" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" Malpighian tubule FBgn0259611 B0613 - http://flybase.org/reports/FBgn0259611 gene - - - B0613 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "anterior crossvein,wing vein L3,wing" FBgn0036599 CG13044 - http://flybase.org/reports/FBgn0036599 protein_coding_gene - - - CG13044 IPR007614:Retinin-like protein CG13044 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0011235 cuc cuckold http://flybase.org/reports/FBgn0011235 "FBgn0010534, FBgn0011243" gene - mating ; GO:0007618 | inferred from mutant phenotype male courtship behavior ; GO:0008049 | inferred from mutant phenotype - "l(2)03264, l(2)10607, ms(2)05158, ms(2)27CD, ms(2)06491, cuc" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,male sterile,behavior defective,partially lethal - majority die" FBgn0024191 sip1 septin interacting protein 1 http://flybase.org/reports/FBgn0024191 FBgn0027543 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR022783 ATP-dependent RNA helicase activity ; GO:0004004 | contributes_to inferred from sequence or structural similarity with SGD:S000004416 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P40797 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR022783 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 spliceosomal complex disassembly ; GO:0000390 | inferred from biological aspect of ancestor with PANTHER:PTN000596045" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay U2-type post-mRNA release spliceosomal complex ; GO:0071008 | inferred from biological aspect of ancestor with PANTHER:PTN000596045 spliceosomal complex ; GO:0005681 | inferred from sequence or structural similarity with UniProtKB:Q9UBB9 precatalytic spliceosome ; GO:0071011 | inferred from direct assay "GH11690, CG7238, BcDNA:GH11690, sip1, Sip1" "IPR000467:G-patch domain, IPR024933:Septin and tuftelin interacting protein, IPR022159:Tuftelin interacting protein, N-terminal domain, IPR022783:GC-rich sequence DNA-binding factor domain" CG7238 27-Aug-18 DroID_v2018_08 Drer\tfip11 Scer\SPP382 Cele\stip-1 Xtro\tfip11 "Mmus\Tfip11, Mmus\Lime1" "Hsap\LIME1, Hsap\TFIP11" "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0085557 CG41026 - http://flybase.org/reports/FBgn0085557 protein_coding_gene - - - CG41026 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0067654 sd-14 sd-14 http://flybase.org/reports/FBgn0067654 gene - neuron-neuron synaptic transmission ; GO:0007270 | inferred from mutant phenotype phototaxis ; GO:0042331 | inferred from mutant phenotype - sd-14 - - 27-Aug-18 DroID_v2018_08 - - - - - - "neurophysiology defective,somatic clone,phototaxis defective,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0025561 anon-36Ab anon-36Ab http://flybase.org/reports/FBgn0025561 - gene - - - "cDNA II, anon-36Ab" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260242 ssar single-strand annealing reducer http://flybase.org/reports/FBgn0260242 gene - double-strand break repair via single-strand annealing ; GO:0045002 | inferred from mutant phenotype - ssar - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065346 l(2)SH1816 lethal (2) SH1816 http://flybase.org/reports/FBgn0065346 gene - - - "l(2)SH1816, l(2)SH2 1816" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0265805 lncRNA:CR44594 - http://flybase.org/reports/FBgn0265805 non_protein_coding_gene - - - CR44594 - CR44594 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065455 l(2)SH1391 lethal (2) SH1391 http://flybase.org/reports/FBgn0065455 gene - - - "l(2)SH1391, l(2)SH2 1391" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0085722 CG41615 - http://flybase.org/reports/FBgn0085722 protein_coding_gene - - - CG41615 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0017622 Eig83B Eig83B http://flybase.org/reports/FBgn0017622 - gene - - - "Eig83, Eig83B" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060502 l(3)S105611 lethal (3) S105611 http://flybase.org/reports/FBgn0060502 gene - - - "1056/11, l(3)S105611" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0066328 rijiy rijiy http://flybase.org/reports/FBgn0066328 gene molecular_function ; GO:0003674 | no biological data available learning or memory ; GO:0007611 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "rijiy, rijiy I" - - 27-Aug-18 DroID_v2018_08 - - - - - - "learning defective,memory defective" FBgn0060401 l(3)S131404 lethal (3) S131404 http://flybase.org/reports/FBgn0060401 gene - - - "1314/04, l(3)S131404" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0031128 hydra hydra http://flybase.org/reports/FBgn0031128 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG1338, hydra" "IPR029017:Enolase N-terminal domain-like, IPR022079:Protein of unknown function DUF3629" CG1338 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0033778 Balat - http://flybase.org/reports/FBgn0033778 protein_coding_gene organic anion transmembrane transporter activity ; GO:0008514 | inferred from biological aspect of ancestor with PANTHER:PTN001936837 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005828 response to ethanol ; GO:0045471 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000756324 "CG3790, CT" "IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG3790 27-Aug-18 DroID_v2018_08 "Drer\slc22a23, Drer\sv2c, Drer\slc22a16, Drer\zgc:175176, Drer\slc22a15, Drer\slc22a7b.1, Drer\slc22a4, Drer\slc22a6l, Drer\slc22a7a, Drer\sv2bb, Drer\si:dkey-166k12.1, Drer\sv2a, Drer\nln, Drer\zgc:153639, Drer\slc22a13, Drer\slc22a17, Drer\LOC100334012, Drer\thop1, Drer\slc22a31, Drer\slc22a2, Drer\svopa" "Scer\PRD1, Scer\JEN1, Scer\PHO84, Scer\GIT1" "Cele\oct-2, Cele\oct-1, Cele\B0361.11, Cele\K05F1.6, Cele\Y82E9BR.16, Cele\B0252.3, Cele\ZK550.3, Cele\svop-1, Cele\F45E10.2" "Xtro\sv2b, Xtro\slc22a5, Xtro\slc22a13, Xtro\slc22a15.2, Xtro\slc22a6, Xtro\sv2c, Xtro\svop, Xtro\slc22a4, Xtro\sv2a" "Mmus\Slc22a1, Mmus\Sv2c, Mmus\Slc22a23, Mmus\Slc22a15, Mmus\Slc22a16, Mmus\Slc22a4, Mmus\Slc22a6, Mmus\Slc22a7, Mmus\Svop, Mmus\Slc22a28, Mmus\Slc22a21, Mmus\Slc22a5, Mmus\Slc22a20, Mmus\Slc22a8, Mmus\Slc22a13, Mmus\Slc22a17, Mmus\Slc22a2, Mmus\Sv2b, Mmus\Sv2a, Mmus\Slc22a3, Mmus\Nln, Mmus\Thop1, Mmus\Slc22a12" "Hsap\SLC22A25, Hsap\SV2A, Hsap\NLN, Hsap\THOP1, Hsap\SLC22A20, Hsap\SVOP, Hsap\SLC22A2, Hsap\SLC22A17, Hsap\SLC22A23, Hsap\SLC22A3, Hsap\SV2B, Hsap\SLC22A6, Hsap\SLC22A16, Hsap\SLC22A8, Hsap\SLC22A4, Hsap\SLC22A13, Hsap\SLC22A1, Hsap\SLC22A5, Hsap\SLC22A12, Hsap\SLC22A31, Hsap\SV2C, Hsap\SLC22A15, Hsap\SLC22A7" "viable,fertile" FBgn0036155 CG6163 - http://flybase.org/reports/FBgn0036155 protein_coding_gene - - - CG6163 IPR006578:MADF domain CG6163 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0060838 l(3)S049604 lethal (3) S049604 http://flybase.org/reports/FBgn0060838 gene - - - "0496/04, l(3)S049604" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0015277 Pi3K59F Phosphotidylinositol 3 kinase 59F http://flybase.org/reports/FBgn0015277 - protein_coding_gene "1-phosphatidylinositol-3-kinase activity ; GO:0016303 | inferred from sequence or structural similarity with SGD:S000004230 1-phosphatidylinositol-3-kinase activity ; GO:0016303 | inferred from direct assay phosphatidylinositol-4,5-bisphosphate 3-kinase activity ; GO:0046934 | NOT inferred from direct assay phosphatidylinositol 3-kinase activity ; GO:0035004 | non-traceable author statement 1-phosphatidylinositol-4-phosphate 3-kinase activity ; GO:0035005 | NOT inferred from direct assay" "phosphatidylinositol-mediated signaling ; GO:0048015 | inferred from electronic annotation with InterPro:IPR008290, InterPro:IPR015433 autophagy ; GO:0006914 | inferred from mutant phenotype dsRNA transport ; GO:0033227 | inferred from mutant phenotype autophagy ; GO:0006914 | inferred from mutant phenotype inferred from genetic interaction with Atg6 regulation of autophagy ; GO:0010506 | inferred from mutant phenotype larval midgut cell programmed cell death ; GO:0035096 | inferred from mutant phenotype positive regulation of nurse cell apoptotic process ; GO:0045850 | inferred from mutant phenotype endocytosis ; GO:0006897 | inferred from mutant phenotype phosphatidylinositol phosphorylation ; GO:0046854 | non-traceable author statement cellular response to starvation ; GO:0009267 | inferred from mutant phenotype neuron remodeling ; GO:0016322 | inferred from mutant phenotype phosphatidylinositol phosphorylation ; GO:0046854 | inferred from sequence or structural similarity with SGD:S000004230 phosphatidylinositol phosphorylation ; GO:0046854 | inferred from direct assay" "phosphatidylinositol 3-kinase complex, class III ; GO:0035032 | non-traceable author statement autophagosome membrane ; GO:0000421 | inferred from direct assay early endosome ; GO:0005769 | inferred from direct assay phosphatidylinositol 3-kinase complex, class III, type I ; GO:0034271 | inferred from direct assay" "PI3K, dPI3K, CG5373, PI(3)K, PI3K-59F, PI3K_59F, DmVps34, VPS34, Pi3K59F, Vps34, vps34, PI[[3]]K, Pi3K_59F, dVps34/PI3K59F, dVps34" "IPR018936:Phosphatidylinositol 3/4-kinase, conserved site, IPR000403:Phosphatidylinositol 3-/4-kinase, catalytic domain, IPR001263:Phosphoinositide 3-kinase, accessory (PIK) domain, IPR002420:Phosphatidylinositol 3-kinase, C2 domain, IPR008290:Phosphatidylinositol 3-kinase, Vps34 type, IPR011009:Protein kinase-like domain, IPR015433:Phosphatidylinositol kinase, IPR016024:Armadillo-type fold, IPR000008:C2 domain" CG5373 27-Aug-18 DroID_v2018_08 Drer\pik3c3 Scer\VPS34 Cele\vps-34 Xtro\pik3c3 Mmus\Pik3c3 Hsap\PIK3C3 "viable,fertile,lethal,starvation stress response defective" "autophagic vacuole | conditional | somatic clone,lysosome | conditional | somatic clone,embryonic/larval fat body,conditional,somatic clone,garland cell,eye disc,autophagic vacuole | somatic clone,nurse cell,germline clone,somatic clone | third instar larval stage,pre-autophagosomal structure membrane | conditional | somatic clone,embryonic/larval fat body | late third instar larval stage" DRSC04640 K -0.456494315 -0.055820369 0.033462154 0.123662986 0.505035764 1.581710572 FBgn0004535 l(4)102ABg lethal (4) 102ABg http://flybase.org/reports/FBgn0004535 - gene - - - "l(4)24, l(4)102ABg" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,lethal,recessive" FBgn0259348 C603 - http://flybase.org/reports/FBgn0259348 gene - - - C603 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing hair,wing,wing vein,chaeta" FBgn0030966 Suox - http://flybase.org/reports/FBgn0030966 protein_coding_gene molybdenum ion binding ; GO:0030151 | inferred from electronic annotation with InterPro:IPR005066 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR018506 sulfite oxidase activity ; GO:0008482 | inferred from sequence or structural similarity with UniProtKB:P51687 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005066, InterPro:IPR008335 nitrate assimilation ; GO:0042128 | inferred from electronic annotation with InterPro:IPR000572 sulfur compound metabolic process ; GO:0006790 | inferred from sequence or structural similarity with UniProtKB:P51687" mitochondrial intermembrane space ; GO:0005758 | inferred from sequence or structural similarity with UniProtKB:P51687 CG7280 "IPR000572:Oxidoreductase, molybdopterin-binding domain, IPR001199:Cytochrome b5-like heme/steroid binding domain, IPR005066:Moybdenum cofactor oxidoreductase, dimerisation, IPR008335:Eukaryotic molybdopterin oxidoreductase, IPR018506:Cytochrome b5, heme-binding site, IPR014756:Immunoglobulin E-set" CG7280 27-Aug-18 DroID_v2018_08 Drer\suox - Cele\suox-1 Xtro\suox Mmus\Suox Hsap\SUOX viable FBgn0010769 l(3)02104 lethal (3) 02104 http://flybase.org/reports/FBgn0010769 - gene - - - l(3)02104 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0035639 kri krishah http://flybase.org/reports/FBgn0035639 protein_coding_gene uracil phosphoribosyltransferase activity ; GO:0004845 | inferred from direct assay uridine kinase activity ; GO:0004849 | inferred from biological aspect of ancestor with PANTHER:PTN000032154 pyrimidine nucleobase metabolic process ; GO:0006206 | inferred from biological aspect of ancestor with PANTHER:PTN000032154 pyrimidine nucleoside salvage ; GO:0043097 | inferred from biological aspect of ancestor with PANTHER:PTN000032154 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000032154 "anon-EST:Posey275, kri, uprt, CG5537" "IPR029057:Phosphoribosyltransferase-like, IPR000836:Phosphoribosyltransferase domain" CG5537 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-243j20.2, Drer\ctnnb2, Drer\uck2b, Drer\jupb, Drer\uckl1a, Drer\ctnnb1, Drer\jupa, Drer\uckl1b, Drer\uck1, Drer\uprt, Drer\uck2a" "Scer\URK1, Scer\FUR1" "Cele\C47B2.2, Cele\F19B6.1" "Xtro\uprt, Xtro\uck2, Xtro\ctnnb1, Xtro\uck1, Xtro\jup" "Mmus\Uckl1, Mmus\Jup, Mmus\Uck1, Mmus\Uck2, Mmus\Ctnnb1, Mmus\Uprt" "Hsap\UCK1, Hsap\UPRT, Hsap\CTNNB1, Hsap\UCK2, Hsap\JUP, Hsap\UCKL1" viable DRSC10515 I 1.571681505 -0.069839514 0.52852737 0.138679518 -0.12533288 0.765727549 FBgn0010811 l(3)03691 lethal (3) 03691 http://flybase.org/reports/FBgn0010811 - gene - - - l(3)03691 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0061011 l(3)S026203b lethal (3) S026203b http://flybase.org/reports/FBgn0061011 gene - - - "0262/03, l(3)S026203b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0060373 l(3)S136708 lethal (3) S136708 http://flybase.org/reports/FBgn0060373 gene - - - "1367/08, l(3)S136708" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0038789 Ir92a Ionotropic receptor 92a http://flybase.org/reports/FBgn0038789 protein_coding_gene ionotropic glutamate receptor activity ; GO:0004970 | inferred from electronic annotation with InterPro:IPR001320 extracellular ammonia-gated ion channel activity ; GO:0036081 | inferred from direct assay olfactory receptor activity ; GO:0004984 | inferred from direct assay detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from direct assay cellular response to ammonia ; GO:1903718 | inferred from direct assay detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from mutant phenotype positive regulation of calcium-mediated signaling ; GO:0050850 | inferred from direct assay cellular response to amine stimulus ; GO:0071418 | inferred from direct assay membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001320 integral component of membrane ; GO:0016021 | inferred from sequence model "Ir92a, CG15685, IR92a, DmelIR92a" IPR001320:Ionotropic glutamate receptor CG15685 27-Aug-18 DroID_v2018_08 - - "Cele\glr-7, Cele\glr-3" - - Hsap\GRID2 "viable,smell perception defective" sensillum coeloconicum of antennal segment 3 FBgn0033431 CG1827 - http://flybase.org/reports/FBgn0033431 protein_coding_gene N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity ; GO:0003948 | inferred from sequence or structural similarity with UniProtKB:P20933 protein deglycosylation ; GO:0006517 | inferred from sequence or structural similarity with UniProtKB:P20933 lysosome ; GO:0005764 | inferred from sequence or structural similarity with UniProtKB:P20933 "CG1827, cg1827" "IPR000246:Peptidase T2, asparaginase 2, IPR029055:Nucleophile aminohydrolases, N-terminal" CG1827 27-Aug-18 DroID_v2018_08 "Drer\aga, Drer\zgc:153169" - Cele\R04B3.2 Xtro\aga Mmus\Aga Hsap\AGA viable FBgn0065495 l(2)SH1224 lethal (2) SH1224 http://flybase.org/reports/FBgn0065495 gene - - - "l(2)SH1224, l(2)SH2 1224" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0053642 CG33642 - http://flybase.org/reports/FBgn0053642 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33642 IPR010512:Protein of unknown function DUF1091 CG33642 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0003357 Jon99Ciii Jonah 99Ciii http://flybase.org/reports/FBgn0003357 "FBgn0001288, FBgn0011833, FBgn0051362" protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" "proteolysis ; GO:0006508 | inferred from sequence model proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - "Ser99Db, 99Calpha, Jon99Cbeta, Jon99Calpha, Jon99Cbetaiii, Jon99Calphaii, SP143, CG15519, SER2, Ser5, Ser2, Jon99C1, Jon99C2, Jon99C, CG31362, JonC, Jon99B, Jon99Ciii" "IPR018114:Serine proteases, trypsin family, histidine active site, IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG31362 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002848 msg missing http://flybase.org/reports/FBgn0002848 - gene - - - "ms, msg" - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,female sterile,male fertile,poor" macrochaeta FBgn0000798 fs(1)de9 female sterile (1) defective eggs 9 http://flybase.org/reports/FBgn0000798 - gene - - - "de9, fs(1)de9" - - 27-Aug-18 DroID_v2018_08 - - - - - - female sterile "endochorion,dorsal appendage,chorion" FBgn0004097 l(2)60De lethal (2) 60De http://flybase.org/reports/FBgn0004097 - gene - - - l(2)60De - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,visible" FBgn0026740 anon-64Ca anon-64Ca http://flybase.org/reports/FBgn0026740 - gene - - - "gene b, anon-64Ca" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0011043 l(1)Stark-b lethal (1) of Stark b http://flybase.org/reports/FBgn0011043 FBgn0010212 gene - - - "l(1)Stark-b, l(1)Sb" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0260047 33AC1 - http://flybase.org/reports/FBgn0260047 gene - - - 33AC1 - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,somatic clone" "wing,somatic clone" FBgn0065204 l(2)SH2285 lethal (2) SH2285 http://flybase.org/reports/FBgn0065204 gene - - - "l(2)SH2285, l(2)SH2 2285" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0034883 Eglp2 Entomoglyceroporin 2 http://flybase.org/reports/FBgn0034883 protein_coding_gene water channel activity ; GO:0015250 | inferred from biological aspect of ancestor with PANTHER:PTN000440615 channel activity ; GO:0015267 | inferred from sequence or structural similarity with Drip ion transmembrane transport ; GO:0034220 | inferred from biological aspect of ancestor with PANTHER:PTN000440615 renal system process ; GO:0003014 | inferred from expression pattern transmembrane transport ; GO:0055085 | inferred from sequence or structural similarity with Drip integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with Drip integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000440615 "CG17664, Aqp17664, Eglp2, Eglp 2" "IPR000425:Major intrinsic protein, IPR034294:Aquaporin transporter, IPR022357:Major intrinsic protein, conserved site, IPR023271:Aquaporin-like" CG17664 27-Aug-18 DroID_v2018_08 "Drer\aqp7, Drer\aqp9b, Drer\mipa, Drer\mipb, Drer\aqp1a.1, Drer\aqp8a.1, Drer\aqp1a.2, Drer\aqp10a, Drer\aqp3a, Drer\aqp8a.2, Drer\aqp4, Drer\aqp8b" "Scer\AQY1, Scer\AQY2, Scer\YFL054C, Scer\FPS1, Scer\YLL053C" "Cele\aqp-2, Cele\aqp-4, Cele\aqp-7, Cele\aqp-6, Cele\aqp-5, Cele\aqp-8, Cele\aqp-12, Cele\aqp-3" "Xtro\LOC100216133, Xtro\mip, Xtro\aqp2, Xtro\aqp5" "Mmus\Aqp3, Mmus\Aqp5, Mmus\Aqp4, Mmus\Aqp1, Mmus\Aqp2, Mmus\Aqp8, Mmus\Mip, Mmus\Aqp7, Mmus\Aqp6, Mmus\Aqp9" "Hsap\AQP10, Hsap\MIP, Hsap\AQP4, Hsap\AQP8, Hsap\AQP3, Hsap\AQP2, Hsap\AQP1, Hsap\AQP6, Hsap\AQP9, Hsap\AQP7, Hsap\AQP5" "viable,visible,lethal" trichogen cell FBgn0262189 mir-2500 mir-2500 stem loop http://flybase.org/reports/FBgn0262189 miRNA_gene - - - "dme-mir-2500, mir-2500, CR42896, miR-2500" - CR42896 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0014848 Eig71Eh Eig71Eh http://flybase.org/reports/FBgn0014848 - protein_coding_gene - defense response to bacterium ; GO:0042742 | inferred from sequence or structural similarity with MGI:MGI:94880 metamorphosis ; GO:0007552 | inferred from expression pattern extracellular region ; GO:0005576 | inferred from sequence model "L71, CG7594, L71-8, Eig71Eh, EIG71-H" IPR003475:Insect protein of unknown function CG7594 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0001294 jyx jaunty-x http://flybase.org/reports/FBgn0001294 - gene - - - jyx - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,reduced,visible" FBgn0266247 lncRNA:CR44942 - http://flybase.org/reports/FBgn0266247 non_protein_coding_gene - - - "CR44942, lincRNA.759" - CR44942 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259653 B0538 - http://flybase.org/reports/FBgn0259653 gene - - - B0538 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing,wing sensillum,ectopic,wing margin bristle,leg,distal" FBgn0025490 l(3)82EFa lethal (3) 82EFa http://flybase.org/reports/FBgn0025490 - gene - - - l(3)82EFa - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0035871 BI-1 Bax Inhibitor-1 http://flybase.org/reports/FBgn0035871 protein_coding_gene endoribonuclease inhibitor activity ; GO:0060698 | inferred from sequence or structural similarity with UniProtKB:P55061 negative regulation of apoptotic process ; GO:0043066 | inferred from electronic annotation with InterPro:IPR006213 negative regulation of cell death ; GO:0060548 | inferred from direct assay negative regulation of endoribonuclease activity ; GO:0060702 | inferred from direct assay negative regulation of autophagy ; GO:0010507 | inferred from mutant phenotype negative regulation of endoplasmic reticulum unfolded protein response ; GO:1900102 | inferred from sequence or structural similarity with HGNC:11723 cellular response to starvation ; GO:0009267 | inferred from mutant phenotype negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response ; GO:1904721 | inferred from direct assay salivary gland cell autophagic cell death ; GO:0035071 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR006213 integral component of membrane ; GO:0016021 | inferred from sequence model protein complex ; GO:0043234 | inferred from sequence or structural similarity with HGNC:11723 "CG7188, d-BI-1, dTmbim6, BI-1, dBI-1" "IPR006213:Bax inhibitor 1, conserved site, IPR006214:Bax inhibitor 1-related" CG7188 27-Aug-18 DroID_v2018_08 Drer\tegt - Cele\K11H12.8 Xtro\tmbim6 Mmus\Tmbim6 Hsap\TMBIM6 "viable,fertile,starvation stress response defective,long lived,nutrition conditional,short lived,chemical conditional" "embryonic/larval salivary gland | pupal stage,lysosome | nutrition conditionalda.G32,fat body,nutrition conditional,autophagic vacuole | nutrition conditionalda.G32" FBgn0053408 5SrRNA:CR33408 5SrRNA:CR33408 http://flybase.org/reports/FBgn0053408 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33408, 5SrRNA:CR33408" - CR33408 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0041589 l(3)S136802 lethal (3) S136802 http://flybase.org/reports/FBgn0041589 gene - - - "1368.02, l(3)S136802" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" presumptive embryonic/larval nervous system FBgn0028973 yew yew http://flybase.org/reports/FBgn0028973 gene - dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype - yew - - 27-Aug-18 DroID_v2018_08 - - - - - - "dendrite | dorsal | embryonic stage,presumptive embryonic/larval peripheral nervous system,dorsal" FBgn0051948 CG31948 - http://flybase.org/reports/FBgn0051948 protein_coding_gene - - - "CG9966, CG31948" "IPR000626:Ubiquitin domain, IPR029071:Ubiquitin-related domain, IPR031961:Domain of unknown function DUF4780" CG31948 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0037184 CG14450 - http://flybase.org/reports/FBgn0037184 protein_coding_gene - - - CG14450 - CG14450 27-Aug-18 DroID_v2018_08 Drer\tefm - - Xtro\tefm Mmus\Tefm Hsap\TEFM FBgn0069407 JJF230 JJF230 http://flybase.org/reports/FBgn0069407 gene - - - JJF230 - - 27-Aug-18 DroID_v2018_08 - - - - - - stress response defective FBgn0044474 EP1493 EP1493 http://flybase.org/reports/FBgn0044474 gene - - - EP1493 - - 27-Aug-18 DroID_v2018_08 - - - - - - neuroanatomy defective "intersegmental nerve,anterior fascicle & synapse" FBgn0261256 wiser wings scalloped-eyes rough http://flybase.org/reports/FBgn0261256 gene - - - wiser - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,heat sensitive,short lived,female sterile,locomotor behavior defective,visible" "wing,metathoracic tarsal segment,adult abdomen,metathoracic leg,ovary,eye" FBgn0052709 CG32709 - http://flybase.org/reports/FBgn0052709 protein_coding_gene - - - "BcDNA:HL05735, CG32709" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039527 CG5639 - http://flybase.org/reports/FBgn0039527 protein_coding_gene "serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223, InterPro:IPR004094" - extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR008197 "CT17816, CG5639" "IPR000716:Thyroglobulin type-1, IPR002223:Pancreatic trypsin inhibitor Kunitz domain, IPR004094:Antistasin-like domain, IPR006150:Cysteine-rich repeat, IPR008197:WAP-type 'four-disulfide core' domain, IPR011061:Hirudin/antistatin, IPR003645:Follistatin-like, N-terminal, IPR028150:Lustrin, cysteine-rich repeated domain" CG5639 27-Aug-18 DroID_v2018_08 "Drer\tnr, Drer\fgb, Drer\zgc:158328, Drer\fgl2b, Drer\wfdc2, Drer\scube1, Drer\zgc:171687, Drer\tnw, Drer\fga, Drer\LOC100007488, Drer\crb2b, Drer\sned1, Drer\dpy19l1l, Drer\LOC100535882, Drer\si:ch211-287a12.9, Drer\si:zfos-2330d3.3, Drer\adgrl4, Drer\si:ch1073-110a20.3, Drer\si:ch211-157b11.8, Drer\fgg, Drer\angptl1a, Drer\tnxba, Drer\svep1, Drer\jag1b, Drer\si:ch73-173h19.3, Drer\angpt1, Drer\si:ch1073-110a20.2, Drer\tnc, Drer\angptl6, Drer\jag2a, Drer\si:zfos-2330d3.1, Drer\ltbp3, Drer\crb2a, Drer\angptl5, Drer\adgrf6, Drer\LOC100332841, Drer\angptl2b, Drer\matn3a, Drer\fibcd1, Drer\fbln7, Drer\LOC562634, Drer\col28a1a, Drer\angptl4, Drer\megf6b, Drer\angpt4, Drer\angptl2a, Drer\efemp1, Drer\angptl3, Drer\zmp:0000000846, Drer\fgl2a, Drer\wu:fj11g02, Drer\si:zfos-2330d3.6, Drer\jag1a, Drer\col28a1a, Drer\jag2b, Drer\dlb, Drer\angpt2b, Drer\si:zfos-2330d3.8, Drer\fbln1, Drer\si:ch211-203k16.3, Drer\scube3, Drer\si:ch1073-110a20.1, Drer\zgc:194887" - "Cele\Y69H2.10, Cele\Y43C5A.2, Cele\ensh-1, Cele\T15B7.1, Cele\C08G9.2, Cele\Y26D4A.12, Cele\W05B2.2, Cele\ZC504.1, Cele\Y69H2.3, Cele\K10D3.4" "Xtro\fcn3, Xtro\fcn1, Xtro\angptl3, Xtro\crb2, Xtro\angptl2, Xtro\svep1, Xtro\fibcd1, Xtro\LOC100497330, Xtro\angptl4, Xtro\f12, Xtro\tnr, Xtro\fgl1, Xtro\col14a1, Xtro\notch1, Xtro\angptl5, Xtro\fgb, Xtro\angpt1, Xtro\jag1, Xtro\fbn1, Xtro\fgl2, Xtro\tnc, Xtro\angpt4, Xtro\ltbp4, Xtro\tnxb, Xtro\tnn, Xtro\matn4, Xtro\hgfac, Xtro\fcn2, Xtro\fga, Xtro\LOC100491105, Xtro\LOC100488177, Xtro\mfap4, Xtro\fgg, Xtro\nell1" "Mmus\Fgl1, Mmus\Fcnb, Mmus\Wfdc17, Mmus\Fcna, Mmus\Dlk2, Mmus\Angpt2, Mmus\Svep1, Mmus\Angptl6, Mmus\Scube3, Mmus\Wfdc15a, Mmus\Wfdc9, Mmus\Wfdc10, Mmus\Angptl2, Mmus\Mfap4, Mmus\Angpt1, Mmus\Wfdc5, Mmus\Tdgf1, Mmus\Jag2, Mmus\Wap, Mmus\Angptl3, Mmus\Sned1, Mmus\Jag1, Mmus\Dll4, Mmus\Wfdc18, Mmus\Fbln7, Mmus\Fgg, Mmus\Tnc, Mmus\Wfdc2, Mmus\Dll3, Mmus\Wfdc11, Mmus\Tnxb, Mmus\Angptl4, Mmus\Col28a1, Mmus\Fgb, Mmus\Tnr, Mmus\Ltbp1, Mmus\Tnn, Mmus\Angptl7, Mmus\Fibcd1, Mmus\Slpi, Mmus\Hgfac, Mmus\Fga, Mmus\Egfl7, Mmus\Dlk1, Mmus\Hmcn2, Mmus\Wfdc16, Mmus\Vwce, Mmus\Angptl1, Mmus\Wfdc15b, Mmus\Vwde, Mmus\Ltbp4, Mmus\Wfdc13, Mmus\Wfdc12, Mmus\Wfdc21, Mmus\Megf6, Mmus\Col22a1, Mmus\Crb2, Mmus\Fbn1, Mmus\Scube2, Mmus\Angpt4, Mmus\Fgl2, Mmus\Matn3, Mmus\Cfc1, Mmus\Vwa1, Mmus\Habp2, Mmus\F12" "Hsap\TDGF1, Hsap\TNR, Hsap\FGL2, Hsap\MATN3, Hsap\ANGPTL3, Hsap\JAG1, Hsap\LOC100996717, Hsap\NOTCH2NL, Hsap\TNXB, Hsap\WFDC11, Hsap\DLK1, Hsap\FGA, Hsap\WFDC10B, Hsap\PI3, Hsap\CRB2, Hsap\SCUBE2, Hsap\FBLN7, Hsap\WFDC5, Hsap\FGG, Hsap\EYS, Hsap\WFDC13, Hsap\WFDC9, Hsap\EGFL7, Hsap\ANGPT4, Hsap\FCN3, Hsap\FGL1, Hsap\ANGPTL2, Hsap\ANGPTL5, Hsap\COL22A1, Hsap\CFC1B, Hsap\TNC, Hsap\WFDC12, Hsap\ANGPTL1, Hsap\ANGPTL4, Hsap\FCN2, Hsap\TG, Hsap\ANGPTL6, Hsap\DLL3, Hsap\VWA1, Hsap\SLPI, Hsap\JAG2, Hsap\FGB, Hsap\SNED1, Hsap\WFDC10A, Hsap\ANGPT2, Hsap\COL14A1, Hsap\ANGPT1, Hsap\VWCE, Hsap\TNN, Hsap\DLK2, Hsap\LTBP1, Hsap\SCUBE3, Hsap\WFDC2, Hsap\DLL4, Hsap\HGFAC, Hsap\F12, Hsap\SVEP1, Hsap\HABP2, Hsap\ANGPTL7, Hsap\FIBCD1, Hsap\CFC1" lethal FBgn0263241 Mocs1 Molybdenum cofactor synthesis 1 http://flybase.org/reports/FBgn0263241 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR000385, InterPro:IPR006638, InterPro:IPR007197, InterPro:IPR013785 4 iron, 4 sulfur cluster binding ; GO:0051539 | inferred from electronic annotation with InterPro:IPR000385, InterPro:IPR010505 metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR000385, InterPro:IPR013483" Mo-molybdopterin cofactor biosynthetic process ; GO:0006777 | inferred from sequence or structural similarity with UniProtKB:Q9NZB8 molybdopterin synthase complex ; GO:0019008 | inferred from electronic annotation with InterPro:IPR010505 "Mocs1, Mosc1A+Mosc1B, mocsI, CG7858, CG33048, Mocs1B, Mocs1A-B, Mocs1A, MocsI, MOCS1A, MOCS1B, lxd, MOCSI" "IPR000385:MoaA/nifB/pqqE, iron-sulphur binding, conserved site, IPR002820:Molybdopterin cofactor biosynthesis C (MoaC) domain, IPR006638:Elongator protein 3/MiaB/NifB, IPR007197:Radical SAM, IPR010505:Molybdenum cofactor synthesis C-terminal, IPR013483:Molybdenum cofactor biosynthesis protein A, IPR013785:Aldolase-type TIM barrel, IPR023045:Molybdenum cofactor biosynthesis C, IPR034481:Main SPASM domain-containing" CG33048 27-Aug-18 DroID_v2018_08 Drer\mocs1 - "Cele\F49H6.5, Cele\F49E2.1" Xtro\mocs1 Mmus\Mocs1 Hsap\MOCS1 FBgn0062533 ff3 ff3 http://flybase.org/reports/FBgn0062533 gene - - - ff3 - - 27-Aug-18 DroID_v2018_08 - - - - - - "mitotic cell cycle defective,meiotic cell cycle defective,male" "mitotic cell cycle,mitotic anaphase,mitotic telophase,cell cycle,nuclear chromosome" FBgn0000003 7SLRNA:CR32864 Signal recognition particle 7SL RNA CR32864 http://flybase.org/reports/FBgn0000003 - non_protein_coding_gene - SRP-dependent cotranslational protein targeting to membrane ; GO:0006614 | inferred from sequence or structural similarity "signal recognition particle, endoplasmic reticulum targeting ; GO:0005786 | inferred from sequence or structural similarity" "7SL RNA, CR32864, 7SLRNA:CR32864, 7SLRNA" - CR32864 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032754 CG10700 - http://flybase.org/reports/FBgn0032754 protein_coding_gene "oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR016156, InterPro:IPR017941, InterPro:IPR023753 2 iron, 2 sulfur cluster binding ; GO:0051537 | inferred from electronic annotation with InterPro:IPR017941 flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR016156" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR004099, InterPro:IPR016156, InterPro:IPR017941, InterPro:IPR023753 execution phase of apoptosis ; GO:0097194 | inferred from sequence or structural similarity with UniProtKB:Q96NN9" - CG10700 "IPR023753:FAD/NAD(P)-binding domain, IPR016156:FAD/NAD-linked reductase, dimerisation domain, IPR017941:Rieske [2Fe-2S] iron-sulphur domain" CG10700 27-Aug-18 DroID_v2018_08 "Drer\aifm3, Drer\aifm4, Drer\aifm2, Drer\aifm5" Scer\AIF1 Cele\F20D6.11 "Xtro\aifm3, Xtro\LOC100498581, Xtro\aifm2" Mmus\Aifm3 Hsap\AIFM3 FBgn0267221 lncRNA:CR45661 - http://flybase.org/reports/FBgn0267221 non_protein_coding_gene - - - CR45661 - CR45661 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040269 T:SS-wg Signal sequence of wg http://flybase.org/reports/FBgn0040269 engineered_tag - - - "T:SS-wg, T:wg" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0283649 elgi early girl http://flybase.org/reports/FBgn0283649 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841, InterPro:IPR013323 acid-amino acid ligase activity ; GO:0016881 | inferred from electronic annotation with InterPro:IPR015036 protein tag ; GO:0031386 | inferred from electronic annotation with InterPro:IPR015036 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:18401 myosin binding ; GO:0017022 | inferred from physical interaction with Myo10A zinc ion binding ; GO:0008270 | inferred from sequence model" protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with HGNC:18401 regulation of meiotic cell cycle ; GO:0051445 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG17033, elgi, dNrdp1, Nrdp1" "IPR001841:Zinc finger, RING-type, IPR008974:TRAF-like, IPR015036:USP8 interacting, IPR017907:Zinc finger, RING-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG17033 27-Aug-18 DroID_v2018_08 "Drer\rnf151, Drer\rnf41" - "Cele\trf-1, Cele\B0432.13" Xtro\rnf41 "Mmus\Rnf151, Mmus\Rnf41" "Hsap\RNF41, Hsap\TRAIP, Hsap\RNF151" "partially lethal - majority die,visible" "mesothoracic tergum,oocyte" DRSC10242 K -0.14044362 0.160000067 -0.497540236 0.464587119 2.217056269 0.745057763 FBgn0267417 CG45770 - http://flybase.org/reports/FBgn0267417 protein_coding_gene - - - "CG45770, Mst77Y" - CG45770 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267812 asRNA:CR46137 - http://flybase.org/reports/FBgn0267812 non_protein_coding_gene - - - CR46137 - CR46137 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005587 anon-alaA anon-alaA http://flybase.org/reports/FBgn0005587 FBgn0004553 repeat_region - - - "ALA-A, ala-A, ALA-repeat, anon-alaA" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085563 CG41233 - http://flybase.org/reports/FBgn0085563 protein_coding_gene - - - CG41233 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264349 lncRNA:CR43805 - http://flybase.org/reports/FBgn0264349 non_protein_coding_gene - - - CR43805 - CR43805 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036860 CG14086 - http://flybase.org/reports/FBgn0036860 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - CG14086 IPR032055:Transmembrane protein 72 CG14086 27-Aug-18 DroID_v2018_08 Drer\tmem72 - - - Mmus\Tmem72 Hsap\TMEM72 viable FBgn0053388 5SrRNA:CR33388 5SrRNA:CR33388 http://flybase.org/reports/FBgn0053388 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33388, 5SrRNA:CR33388" - CR33388 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038901 Burs Bursicon http://flybase.org/reports/FBgn0038901 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with UniProtKB:Q9VJS7 neuropeptide hormone activity ; GO:0005184 | contributes_to inferred by curator from GO:0031395 neuropeptide receptor binding ; GO:0071855 | contributes_to inferred from physical interaction with rk hormone activity ; GO:0005179 | inferred from mutant phenotype neuropeptide hormone activity ; GO:0005184 | contributes_to inferred from direct assay intestinal stem cell homeostasis ; GO:0036335 | inferred from mutant phenotype cuticle pigmentation ; GO:0048067 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype chitin-based cuticle sclerotization ; GO:0007593 | inferred from mutant phenotype border follicle cell delamination ; GO:0030709 | inferred from mutant phenotype bursicon neuropeptide hormone complex ; GO:0031395 | inferred from physical interaction with Pburs terminal bouton ; GO:0043195 | inferred from direct assay extracellular region ; GO:0005576 | inferred from direct assay bursicon neuropeptide hormone complex ; GO:0031395 | inferred from direct assay "CG13419, bursalpha, frl, Bursalpha, burs-alpha, BURS, Burs-alpha, burs, burs alpha, Burs, Burs alpha, Bur alpha" "IPR006207:Cystine knot, C-terminal, IPR029034:Cystine-knot cytokine, IPR004133:DAN" CG13419 27-Aug-18 DroID_v2018_08 - - - - Mmus\Muc5b - "viable,visible,recessive,lethal - all die before end of P-stage,some die during pharate adult stage" "wing,adult cuticle,adult abdomen,posterior scutellar bristle,adult thorax" FBgn0263086 CG43354 - http://flybase.org/reports/FBgn0263086 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43354, lincRNA.182" - CG43354 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0003989 vr varnished http://flybase.org/reports/FBgn0003989 - gene - - - vr - - 27-Aug-18 DroID_v2018_08 - - - - - - female sterile "eye,ommatidium" FBgn0267958 lncRNA:CR46238 - http://flybase.org/reports/FBgn0267958 non_protein_coding_gene - - - "CR46238, lincRNA.760" - CR46238 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0011077 l(1)Q31 lethal (1) Q31 http://flybase.org/reports/FBgn0011077 FBgn0010210 gene - - - l(1)Q31 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0013341 Su(var)25F26B Su(var)25F26B http://flybase.org/reports/FBgn0013341 - gene - - - Su(var)25F26B - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002200 l(3)67Ad lethal (3) 67Ad http://flybase.org/reports/FBgn0002200 - gene - - - l(3)67Ad - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0266967 lncRNA:CR45418 - http://flybase.org/reports/FBgn0266967 non_protein_coding_gene - - - CR45418 - CR45418 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0016821 l(1)L8 lethal (1) L8 http://flybase.org/reports/FBgn0016821 - gene - - - "l(1)L8, L8" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0003429 slo slowpoke http://flybase.org/reports/FBgn0003429 FBgn0046797 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Slob large conductance calcium-activated potassium channel activity ; GO:0060072 | inferred from biological aspect of ancestor with PANTHER:PTN000002875 calcium-activated potassium channel activity ; GO:0015269 | inferred from direct assay calcium-activated potassium channel activity ; GO:0015269 | non-traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P12370 voltage-gated potassium channel activity ; GO:0005249 | inferred from biological aspect of ancestor with PANTHER:PTN000002873 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8MR31 "transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005821 circadian rhythm ; GO:0007623 | inferred from mutant phenotype potassium ion transport ; GO:0006813 | inferred from direct assay circadian behavior ; GO:0048512 | inferred from mutant phenotype male courtship behavior, veined wing generated song production ; GO:0045433 | inferred from mutant phenotype potassium ion transport ; GO:0006813 | non-traceable author statement male courtship behavior, veined wing generated song production ; GO:0045433 | non-traceable author statement response to drug ; GO:0042493 | inferred from mutant phenotype regulation of synaptic growth at neuromuscular junction ; GO:0008582 | inferred from mutant phenotype negative regulation of neuromuscular synaptic transmission ; GO:1900074 | inferred from mutant phenotype locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype" plasma membrane ; GO:0005886 | non-traceable author statement membrane ; GO:0016020 | inferred from direct assay voltage-gated potassium channel complex ; GO:0008076 | inferred from biological aspect of ancestor with PANTHER:PTN000002873 neuron projection ; GO:0043005 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay "dSlo, dslo, Dslo, CG10693, fSlo, BcDNA:GH10751, slo, Slo, Slo1, dSlo1" "IPR003929:Potassium channel, BK, alpha subunit, IPR005821:Ion transport domain, IPR016040:NAD(P)-binding domain, IPR024939:Calcium-activated potassium channel Slo-1, IPR028325:Voltage-gated potassium channel" CG10693 27-Aug-18 DroID_v2018_08 "Drer\kcnma1a, Drer\kcnma1b" - Cele\slo-1 Xtro\kcnma1 "Mmus\Kcnu1, Mmus\Kcnma1" "Hsap\KCNU1, Hsap\KCNMA1" adult stage adult head

"flight defective,viable,fertile,chemosensitive behavior defective,neurophysiology defective,chemical sensitive,circadian rhythm defective,recessive,behavior defective,chemical resistant,neuroanatomy defective,courtship behavior defective,male,heat sensitive,lethal" "antennal basiconic sensillum ab12,adult olfactory receptor neuron ab11a,indirect flight muscle,neuron,NMJ bouton,supernumerary,neuromuscular junction,muscle fiber,heat sensitive,neuromuscular junction | heat sensitive" FBgn0024688 aos::vn argos::vn http://flybase.org/reports/FBgn0024688 - engineered_fusion_gene - - - "gil::vn, argos::vn, aos::vn" - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing vein,eye,ommatidium,anterior crossvein,wing,ectopic,posterior" FBgn0037410 Osi2 Osiris 2 http://flybase.org/reports/FBgn0037410 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of plasma membrane ; GO:0005887 | inferred from sequence model "Osi2, CG1148" IPR012464:Protein of unknown function DUF1676 CG1148 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" FBgn0037186 CG11241 - http://flybase.org/reports/FBgn0037186 protein_coding_gene alanine-glyoxylate transaminase activity ; GO:0008453 | inferred from biological aspect of ancestor with PANTHER:PTN000241036 identical protein binding ; GO:0042802 | inferred from biological aspect of ancestor with PANTHER:PTN000241033 pyridoxal phosphate binding ; GO:0030170 | inferred from biological aspect of ancestor with PANTHER:PTN000241033 - mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000241036 CG11241 "IPR005814:Aminotransferase class-III, IPR015421:Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015424:Pyridoxal phosphate-dependent transferase, IPR015422:Pyridoxal phosphate-dependent transferase, subdomain 2" CG11241 27-Aug-18 DroID_v2018_08 Drer\agxt2 Scer\ARG8 Cele\T09B4.8 Xtro\agxt2 Mmus\Agxt2 Hsap\AGXT2 FBgn0036815 HipHop HP1-HOAP-interacting protein http://flybase.org/reports/FBgn0036815 protein_coding_gene - CENP-A containing nucleosome assembly ; GO:0034080 | inferred from genetic interaction with Chrac-14 neurogenesis ; GO:0022008 | inferred from mutant phenotype protection from non-homologous end joining at telomere ; GO:0031848 | inferred from direct assay "chromosome, telomeric region ; GO:0000781 | inferred from direct assay" "CG6874, BcDNA:RE10558, hiphop, HipHop, l(3)neo26, HIPHOP, Hiphop" - CG6874 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of first instar larval stage,recessive,some die during first instar larval stage,lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0033280 CG12126 - http://flybase.org/reports/FBgn0033280 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT16918, CG12126" - CG12126 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0027112 mei-P8 mei-P8 http://flybase.org/reports/FBgn0027112 - gene - - - mei-P8 - - 27-Aug-18 DroID_v2018_08 - - - - - - meiotic cell cycle defective FBgn0266147 lncRNA:CR44853 - http://flybase.org/reports/FBgn0266147 non_protein_coding_gene - - - CR44853 - CR44853 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002477 l(3)SG32 lethal (3) SG32 http://flybase.org/reports/FBgn0002477 - gene - - - "l(3)C21L, l(3)SG32" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0067787 anon-i118 anon-i118 http://flybase.org/reports/FBgn0067787 gene - - - "i118, anon-i118" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0053767 CG33767 - http://flybase.org/reports/FBgn0053767 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG14458, CG33767" IPR010512:Protein of unknown function DUF1091 CG33767 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0024734 PRL-1 PRL-1 phosphatase http://flybase.org/reports/FBgn0024734 "FBgn0027875, FBgn0062445" protein_coding_gene protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | inferred from electronic annotation with InterPro:IPR000340 protein tyrosine phosphatase activity ; GO:0004725 | inferred from sequence or structural similarity with RGD:61970 prenylated protein tyrosine phosphatase activity ; GO:0004727 | inferred from sequence or structural similarity protein tyrosine phosphatase activity ; GO:0004725 | inferred from biological aspect of ancestor with PANTHER:PTN000596945 protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | non-traceable author statement protein dephosphorylation ; GO:0006470 | non-traceable author statement peptidyl-tyrosine dephosphorylation ; GO:0035335 | inferred from sequence or structural similarity with RGD:61970 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000596947 cytoplasm ; GO:0005737 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "PRL, CG4993, BG:DS07473.3, BcDNA:RE40268, PRL-1, PrL-1, dPRL-1, PRL1" "IPR000387:Tyrosine specific protein phosphatases domain, IPR029021:Protein-tyrosine phosphatase-like, IPR000340:Dual specificity phosphatase, catalytic domain" CG4993 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-251p5.5, Drer\ptp4a1, Drer\ptp4a2b, Drer\ptp4a2a, Drer\ptp4a3" - Cele\T19D2.2 "Xtro\ptp4a3, Xtro\ptp4a1, Xtro\ptp4a2" "Mmus\Ptp4a1, Mmus\Ptp4a2, Mmus\Ptp4a3" "Hsap\PTP4A2, Hsap\PTP4A3, Hsap\PTP4A1" "viable,fertile,size defective,somatic clone,hypoplasia,lethal - all die before end of larval stage,majority die during first instar larval stage,wild-type,partially lethal - majority die,recessive" "wing,eye,somatic clone,head capsule,wing disc" DRSC27332 IK 3.596079543 0.235626341 0.769394229 0.342403053 0.316581321 1.766985396 FBgn0067360 l(2)NC83 lethal (2) NC83 http://flybase.org/reports/FBgn0067360 gene - - - "NC83, l(2)NC83" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0070036 3R-69-15 3R-69-15 http://flybase.org/reports/FBgn0070036 gene molecular_function ; GO:0003674 | no biological data available oocyte dorsal/ventral axis specification ; GO:0007310 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available 3R-69-15 - - 27-Aug-18 DroID_v2018_08 - - - - - - "egg,germline clone,maternal effect,dorsal appendage,non-rescuable maternal effect" FBgn0067060 P307 P307 http://flybase.org/reports/FBgn0067060 gene - - - P307 - - 27-Aug-18 DroID_v2018_08 - - - - - - neurophysiology defective FBgn0013636 l(4)ry1 lethal (4) ry1 http://flybase.org/reports/FBgn0013636 - gene - - - "l(4)1, l(4)ry1" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0045971 PdL75A3 PdL75A3 http://flybase.org/reports/FBgn0045971 gene - - - PdL75A3 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0265178 CG44243 - http://flybase.org/reports/FBgn0265178 protein_coding_gene lipoyltransferase activity ; GO:0017118 | inferred from sequence or structural similarity with UniProtKB:Q9HKT1 lipoate-protein ligase activity ; GO:0016979 | inferred from biological aspect of ancestor with PANTHER:PTN000285675 protein lipoylation ; GO:0009249 | inferred from biological aspect of ancestor with PANTHER:PTN000285675 protein lipoylation ; GO:0009249 | inferred from sequence or structural similarity with UniProtKB:Q9HKT1 cellular_component ; GO:0005575 | no biological data available "CG44243, CG8446" "IPR004143:Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain, IPR004562:Lipoyltransferase/lipoate-protein ligase" CG44243 27-Aug-18 DroID_v2018_08 "Drer\lipt1, Drer\mrps36" Scer\AIM22 Cele\C45G3.3 "Xtro\mrps36, Xtro\lipt1" "Mmus\Lipt1, Mmus\Mrps36" Hsap\LIPT1 FBgn0060978 l(3)S028705b lethal (3) S028705b http://flybase.org/reports/FBgn0060978 gene - - - "0287/05, l(3)S028705b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0065281 l(2)SH2031 lethal (2) SH2031 http://flybase.org/reports/FBgn0065281 gene - - - "l(2)SH2031, l(2)SH2 2031" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0265733 lncRNA:CR44540 - http://flybase.org/reports/FBgn0265733 non_protein_coding_gene - - - CR44540 - CR44540 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035470 Ccz1 "Caffeine, calcium, zinc sensitivity 1" http://flybase.org/reports/FBgn0035470 protein_coding_gene Rab guanyl-nucleotide exchange factor activity ; GO:0017112 | contributes_to inferred from sequence or structural similarity with SGD:S000000335 endosome to lysosome transport via multivesicular body sorting pathway ; GO:0032510 | inferred from direct assay vesicle-mediated transport ; GO:0016192 | inferred from biological aspect of ancestor with PANTHER:PTN000316458 positive regulation of GTPase activity ; GO:0043547 | inferred from sequence or structural similarity with SGD:S000000335 autophagy ; GO:0006914 | inferred from sequence or structural similarity with SGD:S000000335 vesicle ; GO:0031982 | inferred from biological aspect of ancestor with PANTHER:PTN000316458 Mon1-Ccz1 complex ; GO:0035658 | inferred from sequence or structural similarity with SGD:S000000335 cytosol ; GO:0005829 | inferred from direct assay "CG14980, Ccz1, Dccz1, C7orf28B, NP_647835" "IPR013176:Protein of unknown function DUF1712, fungi" CG14980 27-Aug-18 DroID_v2018_08 Drer\ccz1 - Cele\ccz-1 Xtro\ccz1b Mmus\Ccz1 "Hsap\CCZ1B, Hsap\CCZ1" "viable,fertile" endosomeptc-559.1 FBgn0029685 CG2938 - http://flybase.org/reports/FBgn0029685 protein_coding_gene - lateral inhibition ; GO:0046331 | inferred from mutant phenotype - CG2938 IPR012419:Cas1p 10 TM acyl transferase domain CG2938 27-Aug-18 DroID_v2018_08 Drer\casd1 - - Xtro\casd1 Mmus\Casd1 Hsap\CASD1 "viable,visible,body color defective" "chaeta,mesothoracic tergum" FBgn0037751 topi matotopetli http://flybase.org/reports/FBgn0037751 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 protein binding ; GO:0005515 | inferred from physical interaction with wuc protein binding ; GO:0005515 | inferred from physical interaction with comr positive regulation of transcription involved in meiotic cell cycle ; GO:0051039 | inferred from mutant phenotype male meiosis ; GO:0007140 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype nuclear chromatin ; GO:0000790 | inferred from direct assay "CG8484, topi, Topi" IPR013087:Zinc finger C2H2-type CG8484 27-Aug-18 DroID_v2018_08 "Drer\LOC100330167, Drer\si:dkey-208k4.2, Drer\si:dkey-56e3.3" Scer\PZF1 "Cele\Y55F3AM.14, Cele\mep-1, Cele\Y111B2A.10, Cele\pzf-1, Cele\spr-4, Cele\hinf-1" - Mmus\Zfp688 "Hsap\ZNF543, Hsap\ZBTB24, Hsap\ZNF331, Hsap\ZNF785" "meiotic cell cycle defective,male,male sterile,viable,female fertile" "spermatid,secondary spermatocyte,nuclear chromosome & primary spermatocyte,primary spermatocyte & nuclear chromosome,primary spermatocyte & nuclear chromosomeby10)" FBgn0022312 l(1)H30.1 lethal (1) H30.1 http://flybase.org/reports/FBgn0022312 - gene - - - "H30.1, l(1)H30.1" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0029897 RpL17 Ribosomal protein L17 http://flybase.org/reports/FBgn0029897 protein_coding_gene "structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR001063, InterPro:IPR005721, InterPro:IPR018260 structural constituent of ribosome ; GO:0003735 | traceable author statement" "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR001063, InterPro:IPR005721, InterPro:IPR018260 centrosome duplication ; GO:0051298 | inferred from mutant phenotype cytoplasmic translation ; GO:0002181 | traceable author statement" large ribosomal subunit ; GO:0015934 | inferred from electronic annotation with InterPro:IPR005721 cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement "CG3203, anon-EST:Posey276, RpL17, Rpl17" "IPR018260:Ribosomal protein L22/L17, conserved site, IPR001063:Ribosomal protein L22/L17, IPR005721:Ribosomal protein L22/L17, eukaryotic/archaeal" CG3203 27-Aug-18 DroID_v2018_08 Drer\rpl17 "Scer\RPL17A, Scer\RPL17B" "Cele\rpl-17, Cele\sir-2.4" "Xtro\rpl17, Xtro\sirt6" "Mmus\Sirt6, Mmus\Rpl17" "Hsap\SIRT6, Hsap\RPL17-C18orf32, Hsap\C18orf32, Hsap\RPL17" "viable,fertile,lethal" DRSC18293 IEK -1.788815557 -1.577283294 -0.596978383 -4.520636137 1.872277332 2.38221562 FBgn0028119 l(3)S061207 lethal (3) S061207 http://flybase.org/reports/FBgn0028119 gene - - - "1226/12, 0671/10, 0612/07, l(3)S122612a, l(3)S061207" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0085788 CR41504 - http://flybase.org/reports/FBgn0085788 pseudogene_attribute - - - CR41504 - CR41504 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005390 fs(1)M3 female sterile (1) M3 http://flybase.org/reports/FBgn0005390 "FBgn0000816, FBgn0004681, FBgn0029829" protein_coding_gene - chorion-containing eggshell formation ; GO:0007304 | inferred from mutant phenotype vitelline membrane formation involved in chorion-containing eggshell formation ; GO:0007305 | inferred from mutant phenotype terminal region determination ; GO:0007362 | inferred from mutant phenotype extracellular region ; GO:0005576 | inferred from sequence or structural similarity external side of plasma membrane ; GO:0009897 | inferred from direct assay "fs(1)ph, fs(1)polehole, fs(1)phl, fs(1)pole hole, fs(1)K646, Fs(1)K646, CG4790, fs(1)M3" IPR015943:WD40/YVTN repeat-like-containing domain CG4790 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,maternal effect,viable" "vitelline membrane,egg,cephalopharyngeal skeleton,maternal effect,head,anterior,telson,abdominal segment 8,ventral furrow,abdominal segment 5,abdominal segment 6,abdominal segment 7,abdominal segment 9,abdominal segment 10,labrum,ocular segment,cephalic furrow,terminalia,embryo,posterior,embryonic abdominal segment 8" FBgn0052277 CG32277 - http://flybase.org/reports/FBgn0052277 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "SP183, CG11531, CG32277" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site" CG32277 27-Aug-18 DroID_v2018_08 - - "Cele\try-1, Cele\svh-1" - Mmus\Klk10 "Hsap\CELA2A, Hsap\KLK10" FBgn0085400 side-V - http://flybase.org/reports/FBgn0085400 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - "CG34371, CG13548, CT32921, CT32922, CG13547, CG13546, CG30188, 34371" "IPR013162:CD80-like, immunoglobulin C2-set, IPR007110:Immunoglobulin-like domain, IPR003961:Fibronectin type III, IPR003599:Immunoglobulin subtype, IPR003598:Immunoglobulin subtype 2, IPR013783:Immunoglobulin-like fold, IPR013106:Immunoglobulin V-set domain" CG34371 27-Aug-18 DroID_v2018_08 Drer\nphs1 - - Xtro\nphs1 Mmus\Nphs1 "Hsap\NPHS1, Hsap\MERTK, Hsap\PSG1" viable FBgn0027132 l(3)B5-1 lethal (3) B5-1 http://flybase.org/reports/FBgn0027132 - gene - - - l(3)B5-1 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0265980 lncRNA:CR44759 - http://flybase.org/reports/FBgn0265980 non_protein_coding_gene - - - "lincRNA.374, CR44759" - CR44759 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060937 l(3)S040708b lethal (3) S040708b http://flybase.org/reports/FBgn0060937 gene - - - "0407/08, l(3)S040708b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0041144 l(1)1Bm lethal (1) 1Bm http://flybase.org/reports/FBgn0041144 gene - - - l(1)1Bm - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0040007 RpL38 Ribosomal protein L38 http://flybase.org/reports/FBgn0040007 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement structural constituent of ribosome ; GO:0003735 | inferred from direct assay translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR002675 cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 cytoplasmic translation ; GO:0002181 | traceable author statement cytosolic ribosome ; GO:0022626 | inferred from direct assay cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement ribosome ; GO:0005840 | inferred from direct assay "CG18001, E-2b, l(2)41Af, M(2)41A, 41Ag, 41Af, CG40278, l(2)EMS45-72, GroupIV, l(2R)A', M(2)S2, l(2)41Ag, M(2)S3, l(2)EMS4-72, l(2)41Ai, BcDNA:RE42506, RpL38, Rp L38" IPR002675:Ribosomal protein L38e CG18001 27-Aug-18 DroID_v2018_08 "Drer\rpl38, Drer\nr2c2ap" Scer\RPL38 Cele\rpl-38 "Xtro\nr2c2ap, Xtro\rpl38" "Mmus\Nr2c2ap, Mmus\Rpl38" "Hsap\RPL38, Hsap\NR2C2AP" "lethal,developmental rate defective,Minute,dominant,partially,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,increased cell size,decreased cell number,recessive" "prothoracic gland,chaeta,wing vein,ectopic,wing,wing hair,wing margin" DRSC07818 IE -2.199442934 -1.515981937 -0.263835024 -4.066607364 0.843777269 1.449596649 FBgn0053679 CG33679 - http://flybase.org/reports/FBgn0053679 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BP1003, CG33679" IPR010512:Protein of unknown function DUF1091 CG33679 27-Aug-18 DroID_v2018_08 - - Cele\K12H4.7 - - - FBgn0065894 l(2)SH0213 lethal (2) SH0213 http://flybase.org/reports/FBgn0065894 gene - - - "l(2)SH0213, l(2)SH2 0213" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0035186 CG13912 - http://flybase.org/reports/FBgn0035186 protein_coding_gene - - - CG13912 - CG13912 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0053480 CG33480 - http://flybase.org/reports/FBgn0053480 protein_coding_gene - - - CG33480 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033304 Cyp6a13 Cyp6a13 http://flybase.org/reports/FBgn0033304 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN001209891" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 defense response to bacterium ; GO:0042742 | inferred from mutant phenotype" - "CG2397, cyp6a13, Cyp6a13, 6a13" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG2397 27-Aug-18 DroID_v2018_08 "Drer\tbxas1, Drer\cyp51, Drer\cyp3c2, Drer\cyp3c1, Drer\cyp3c3, Drer\cyp3c4, Drer\cyp3a65" Scer\ERG11 "Cele\cyp-25A6, Cele\cyp-25A4, Cele\cyp-13A12, Cele\cyp-13B1, Cele\cyp-25A2, Cele\cyp-44A1, Cele\cyp-13A6, Cele\cyp-35B1, Cele\cyp-13A2, Cele\cyp-13A1, Cele\cyp-25A3, Cele\cyp-13A10, Cele\cyp-13B2, Cele\cyp-25A1, Cele\cyp-13A8, Cele\cyp-13A4, Cele\cyp-13A11, Cele\cyp-13A7, Cele\cyp-13A5, Cele\cyp-43A1, Cele\cyp-13A3" "Xtro\LOC100494419, Xtro\cyp3a5, Xtro\tbxas1, Xtro\cyp3a4" "Mmus\Cyp3a13, Mmus\Cyp3a16, Mmus\Cyp3a41a, Mmus\Cyp3a25, Mmus\Cyp3a57, Mmus\Cyp3a59, Mmus\Cyp3a44, Mmus\Cyp3a11, Mmus\Cyp3a41b, Mmus\Cyp51, Mmus\Tbxas1" "Hsap\CYP3A7-CYP3A51P, Hsap\TBXAS1, Hsap\CYP3A43, Hsap\CYP3A5, Hsap\CYP3A7, Hsap\CYP3A4" "viable,fertile" FBgn0051708 DIP-zeta Dpr-interacting protein zeta http://flybase.org/reports/FBgn0051708 protein_coding_gene - synapse organization ; GO:0050808 | inferred from expression pattern integral component of plasma membrane ; GO:0005887 | inferred from sequence model "CT32338, CT32337, CG13105, CG13104, CG13103, CG31708, DIP-zeta, 31708" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set" CG31708 27-Aug-18 DroID_v2018_08 "Drer\kirrelb, Drer\f11r.2, Drer\LOC100151468, Drer\mxra8a, Drer\esamb, Drer\dscama, Drer\vsig8a, Drer\cd4-2, Drer\ncam1b, Drer\cd4-1, Drer\jam3a, Drer\negr1, Drer\jam3b, Drer\si:ch1073-459j12.1, Drer\si:ch211-215e19.3, Drer\itgb4, Drer\kirrel3a, Drer\igsf9a, Drer\lrit3b, Drer\f11r.1, Drer\si:dkey-250k15.10, Drer\zgc:110372, Drer\lrit1b, Drer\jam2b, Drer\ush2a, Drer\jam2a, Drer\esama, Drer\cxadr, Drer\pigrl4.2, Drer\kirrel3l, Drer\lrit1a, Drer\lrit3a, Drer\zgc:153073, Drer\gpa33, Drer\si:ch211-9d9.7, Drer\paplna, Drer\ntm, Drer\kirrela, Drer\sdk1b, Drer\sdk1a, Drer\cxcr3.1, Drer\si:dkey-65b12.12, Drer\kirrel3b, Drer\vsig8b, Drer\opcml, Drer\igsf11, Drer\si:zfos-1011f11.1, Drer\igsf9bb, Drer\mxra8b" - "Cele\zig-1, Cele\zig-11, Cele\zig-7, Cele\rig-5" "Xtro\lsamp, Xtro\igsf9b, Xtro\lrit3, Xtro\ntm, Xtro\kirrel2, Xtro\papln, Xtro\negr1" "Mmus\Igsf5, Mmus\Lrit3, Mmus\Kirrel2, Mmus\Jam2, Mmus\F11r, Mmus\Lsamp, Mmus\Ntm, Mmus\Ptprq, Mmus\Jam3, Mmus\Vsig2, Mmus\Negr1, Mmus\Gpa33, Mmus\Vsir, Mmus\Gm1123, Mmus\Hepacam2, Mmus\Igsf11, Mmus\Vsig1, Mmus\Papln, Mmus\Clmp, Mmus\Kirrel, Mmus\Sdk1, Mmus\Esam, Mmus\Mxra8, Mmus\Vsig8, Mmus\Igsf9b, Mmus\Opcml, Mmus\Cxadr, Mmus\Iglon5, Mmus\Kirrel3, Mmus\Lrit1" "Hsap\VSIG2, Hsap\ESAM, Hsap\VSIG1, Hsap\KIRREL2, Hsap\CLMP, Hsap\CXADR, Hsap\PAPLN, Hsap\KIRREL3, Hsap\C1orf204, Hsap\KIRREL, Hsap\USH2A, Hsap\LRIT1, Hsap\IGLON5, Hsap\F11R, Hsap\JAM3, Hsap\VSIG8, Hsap\JAM2, Hsap\LRIT3, Hsap\SDK1, Hsap\IGSF5, Hsap\OPCML, Hsap\IGSF9B, Hsap\LSAMP, Hsap\IGSF11, Hsap\MXRA8, Hsap\C10orf54, Hsap\NEGR1, Hsap\GPA33, Hsap\NTM" "lethal - all die before end of pupal stage,some die during pupal stage" DRSC02204 IE 1.129054264 -2.455230506 1.574180181 1.700076426 0.178792256 -0.648791747 FBgn0039311 CG10513 - http://flybase.org/reports/FBgn0039311 protein_coding_gene - - - "CT29500, CG10513" "IPR015897:CHK kinase-like, IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain" CG10513 27-Aug-18 DroID_v2018_08 - - "Cele\dhs-27, Cele\H06H21.8, Cele\F56A4.5, Cele\E02C12.10, Cele\E02C12.8, Cele\C18B10.6, Cele\F59B1.10, Cele\C29F7.2, Cele\Y45G12C.4, Cele\nhr-246, Cele\E02C12.9, Cele\F58B4.5, Cele\C29F7.1, Cele\H37A05.2, Cele\E02C12.6" - - - viable FBgn0265050 asRNA:CR44165 - http://flybase.org/reports/FBgn0265050 non_protein_coding_gene - - - CR44165 - CR44165 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0043474 micropia\pol micropia element pol http://flybase.org/reports/FBgn0043474 transposable_element_gene - - - micropia\pol - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266959 lncRNA:CR45410 - http://flybase.org/reports/FBgn0266959 non_protein_coding_gene - - - CR45410 - CR45410 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033893 CG18371 - http://flybase.org/reports/FBgn0033893 protein_coding_gene acylphosphatase activity ; GO:0003998 | inferred from biological aspect of ancestor with PANTHER:PTN000003030 - - CG18371 "IPR001792:Acylphosphatase-like domain, IPR017968:Acylphosphatase, conserved site, IPR020456:Acylphosphatase" CG18371 27-Aug-18 DroID_v2018_08 "Drer\acyp2, Drer\acyp1" - - "Xtro\acyp2, Xtro\acyp1" "Mmus\Acyp2, Mmus\Acyp1" "Hsap\ACYP1, Hsap\ACYP2" viable FBgn0010025 E(Dl)F10 Enhancer of Delta F10 http://flybase.org/reports/FBgn0010025 - gene - - - E(Dl)F10 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0022029 l(2)k01209 lethal (2) k01209 http://flybase.org/reports/FBgn0022029 "FBgn0022251, FBgn0034213" protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR006083 uridine kinase activity ; GO:0004849 | inferred from sequence or structural similarity with SGD:S000005295 uridine kinase activity ; GO:0004849 | inferred from biological aspect of ancestor with PANTHER:PTN000032154 pyrimidine nucleoside salvage ; GO:0043097 | inferred from biological aspect of ancestor with PANTHER:PTN000032154 pyrimidine-containing compound salvage ; GO:0008655 | inferred from sequence or structural similarity with SGD:S000005295 pyrimidine nucleobase metabolic process ; GO:0006206 | inferred from biological aspect of ancestor with PANTHER:PTN000032154 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000005295 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000005295 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000032154 "CG4798, l(2)k08901, l(2)k01209, l(2)K01209" "IPR000764:Uridine kinase-like, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR029057:Phosphoribosyltransferase-like, IPR006083:Phosphoribulokinase/uridine kinase, IPR000836:Phosphoribosyltransferase domain" CG4798 27-Aug-18 DroID_v2018_08 "Drer\jupa, Drer\ctnnb2, Drer\uckl1a, Drer\uprt, Drer\jupb, Drer\uck1, Drer\si:ch211-243j20.2, Drer\uck2b, Drer\uck2a, Drer\uckl1b, Drer\ctnnb1" "Scer\FUR1, Scer\NRK1, Scer\URK1" "Cele\C47B2.2, Cele\F19B6.1" "Xtro\ctnnb1, Xtro\jup, Xtro\uck1, Xtro\uck2, Xtro\uckl1, Xtro\uprt" "Mmus\Uck1, Mmus\Jup, Mmus\Uckl1, Mmus\Ctnnb1, Mmus\Uprt, Mmus\Uck2" "Hsap\UCKL1, Hsap\UCK1, Hsap\UPRT, Hsap\JUP, Hsap\UCK2, Hsap\CTNNB1" "lethal,recessive,viable,fertile" FBgn0263883 l(3)G34 - http://flybase.org/reports/FBgn0263883 gene - - - l(3)G34 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,mitotic cell cycle defective,somatic clone" "embryonic/larval brain,somatic clone,embryonic/larval neuroblast" FBgn0053220 CG33220 - http://flybase.org/reports/FBgn0053220 protein_coding_gene - - - CG33220 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0024582 l(3)rO220 lethal (3) rO220 http://flybase.org/reports/FBgn0024582 - gene - - - l(3)rO220 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0033828 CG17048 - http://flybase.org/reports/FBgn0033828 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG17048 "IPR001841:Zinc finger, RING-type, IPR017907:Zinc finger, RING-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG17048 27-Aug-18 DroID_v2018_08 - - "Cele\T02C1.1, Cele\K09F6.7, Cele\nhl-1, Cele\T24D1.3" - Mmus\Bfar Hsap\BFAR viable FBgn0262421 mir-13b-2 mir-13b-2 stem loop http://flybase.org/reports/FBgn0262421 miRNA_gene - - - "miR-13b-2, mir-13b, mir-13b-2, dme-mir-13b-2, Dme-miR-13b, 13b-1/2, CR42972, miR-13b, miR-13, CR33079, miR-13B, miR-13-b2, dme-mir-13b, dme-miR-13b, dme-miR-13b-2" - CR42972 27-Aug-18 DroID_v2018_08 - - - - - - embryonic stage -- adult stage viable FBgn0085337 CG34308 - http://flybase.org/reports/FBgn0085337 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin-like protein conjugating enzyme binding ; GO:0044390 | inferred from biological aspect of ancestor with PANTHER:PTN000267874 ubiquitin protein ligase activity involved in ERAD pathway ; GO:1904264 | inferred from biological aspect of ancestor with PANTHER:PTN000267874 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN000267874 ER-associated misfolded protein catabolic process ; GO:0071712 | inferred from biological aspect of ancestor with PANTHER:PTN000267874 Derlin-1 retrotranslocation complex ; GO:0036513 | inferred from biological aspect of ancestor with PANTHER:PTN000267874 CG34308 "IPR001841:Zinc finger, RING-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR017907:Zinc finger, RING-type, conserved site" CG34308 27-Aug-18 DroID_v2018_08 "Drer\rnf185, Drer\rnf5, Drer\timeless" Scer\TOF1 Cele\rnf-5 Xtro\timeless "Mmus\Rnf185, Mmus\Rnf5, Mmus\Timeless" "Hsap\TIMELESS, Hsap\RNF5, Hsap\RNF185" FBgn0262943 lncRNA:CR43262 - http://flybase.org/reports/FBgn0262943 non_protein_coding_gene - - - CR43262 - CR43262 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0027790 GV1 GV1 http://flybase.org/reports/FBgn0027790 "FBgn0035278, FBgn0061378" protein_coding_gene DNA binding ; GO:0003677 | inferred from direct assay biological_process ; GO:0008150 | no biological data available nuclear membrane ; GO:0031965 | colocalizes_with inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "DIP1, CG12023, BcDNA:RH49123, GV1" - CG12023 27-Aug-18 DroID_v2018_08 - - - - - - embryonic stage -- adult stage organism

embryonic stage organism

viable FBgn0266149 lncRNA:CR44855 - http://flybase.org/reports/FBgn0266149 non_protein_coding_gene - - - CR44855 - CR44855 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060413 l(3)S129803 lethal (3) S129803 http://flybase.org/reports/FBgn0060413 gene - - - "1298/03, l(3)S129803" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0264302 CG43780 - http://flybase.org/reports/FBgn0264302 protein_coding_gene - - - "CG43780, CG8600" - CG43780 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" FBgn0036949 CG7290 - http://flybase.org/reports/FBgn0036949 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG7290 IPR002557:Chitin binding domain CG7290 27-Aug-18 DroID_v2018_08 Drer\thbd - "Cele\R02F2.4, Cele\cpg-2, Cele\C39D10.7, Cele\cpg-1" - - Hsap\MATN2 viable FBgn0013632 l(3)neo51 lethal (3) neo51 http://flybase.org/reports/FBgn0013632 - gene - - - l(3)neo51 - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,lethal,recessive" FBgn0031677 CG14036 - http://flybase.org/reports/FBgn0031677 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 copper ion homeostasis ; GO:0055070 | inferred from mutant phenotype - CG14036 "IPR013087:Zinc finger C2H2-type, IPR022776:TRM13/UPF0224 family, U11-48K-like CHHC zinc finger domain" CG14036 27-Aug-18 DroID_v2018_08 "Drer\zgc:56699, Drer\LOC100535654" - Cele\T06A10.3 "Xtro\gtsf1, Xtro\LOC100145274" "Mmus\BC048502, Mmus\Gtsf1l, Mmus\Gtsf1, Mmus\Zfp850" "Hsap\GTSF1L, Hsap\GTSF1" viable FBgn0065864 l(2)SH0267 lethal (2) SH0267 http://flybase.org/reports/FBgn0065864 gene - - - l(2)SH0267 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0003473 sph sparse hairs http://flybase.org/reports/FBgn0003473 - gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "l(1)x-4, l(1)sph, x-4, R-9-5, 4P1, l(1)R-9-5, X-4, l(1)X-4, lX4, l4P1, 30, 27, 26, 18, l(1)S1, l(1)7-96, l(1)20Ea, sph" - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive,heat sensitive,lethal,cell lethal,germline clone,lethal - all die before end of larval stage,some die during larval stage" "adult thorax & microchaeta,eye,wing,adult thorax & microchaeta | conditional ts,heat sensitive,ovariole,germline clone,egg" FBgn0002103 l(2)57Dd lethal (2) 57Dd http://flybase.org/reports/FBgn0002103 - gene - - - l(2)57Dd - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0032805 CG10337 - http://flybase.org/reports/FBgn0032805 protein_coding_gene - - - CG10337 IPR006593:Cytochrome b561/ferric reductase transmembrane CG10337 27-Aug-18 DroID_v2018_08 "Drer\cyb561d1, Drer\cyb561d2" - - - "Mmus\Cyb561d1, Mmus\Cyb561d2" "Hsap\CYB561D1, Hsap\CYB561D2" viable FBgn0027930 MP1 Melanization Protease 1 http://flybase.org/reports/FBgn0027930 - protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR006604, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 melanization defense response ; GO:0035006 | inferred from mutant phenotype proteolysis ; GO:0006508 | inferred from sequence model response to fungus ; GO:0009620 | inferred from expression pattern" - "CG1102, SP25, proPO-AE, BEST:GH02921, MP1" "IPR018114:Serine proteases, trypsin family, histidine active site, IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR022700:Proteinase, regulatory CLIP domain, IPR033116:Serine proteases, trypsin family, serine active site" CG1102 27-Aug-18 DroID_v2018_08 - - "Cele\try-1, Cele\svh-1" - Mmus\C2 - "developmental rate defective,melanotic mass phenotype,lethal - all die before end of larval stage,some die during larval stage,lethal,wound healing defective,viable" "melanotic mass | larval stage,melanotic mass | P-stage,melanotic mass | adult stage" FBgn0083022 snoRNA:Psi18S-640e snoRNA:Psi18S-640e http://flybase.org/reports/FBgn0083022 snoRNA_gene - - - "snoRNA:Psi18S-640e, psi18s-640e, CR34581" - CR34581 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0028952 Kebab Kinetochore and EB1 associated basic protein http://flybase.org/reports/FBgn0028952 protein_coding_gene kinetochore binding ; GO:0043515 | inferred from direct assay microtubule binding ; GO:0008017 | inferred from direct assay biological_process ; GO:0008150 | no biological data available condensed chromosome kinetochore ; GO:0000777 | colocalizes_with inferred from direct assay spindle microtubule ; GO:0005876 | colocalizes_with inferred from direct assay perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay "n(2)k09932, BEST:LD15963, CG4248, Kebab, kebab, keb, CG31672" - CG31672 27-Aug-18 DroID_v2018_08 - - Cele\unc-95 - - Hsap\RHOA "viable,fertile" FBgn0259863 Su(Ste):CR42432 Su(Ste):CR42432 http://flybase.org/reports/FBgn0259863 non_protein_coding_gene - - - "Su(Ste):CR42432, CR42432" - CR42432 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051659 CG31659 - http://flybase.org/reports/FBgn0051659 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "CG16933, CG31659" "IPR012674:Calycin, IPR022271:Lipocalin, ApoD type" CG31659 27-Aug-18 DroID_v2018_08 "Drer\apoda.1, Drer\apoda.2, Drer\apodb" - Cele\lpr-4 - Mmus\Apod Hsap\APOD viable FBgn0003626 Su(var)314 Suppressor of variegation 314 http://flybase.org/reports/FBgn0003626 - gene - - - Su(var)314 - - 27-Aug-18 DroID_v2018_08 - - - - - - "suppressor of variegation,dominant,viable" FBgn0030657 cerv cervantes http://flybase.org/reports/FBgn0030657 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR004181 SUMO transferase activity ; GO:0019789 | contributes_to inferred from sequence or structural similarity with SGD:S000000745 double-strand break repair via homologous recombination ; GO:0000724 | inferred from electronic annotation with InterPro:IPR026846 DNA repair ; GO:0006281 | inferred from sequence or structural similarity with SGD:S000000745 Smc5-Smc6 complex ; GO:0030915 | inferred from sequence or structural similarity with SGD:S000000745 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000000745 "cerv, CG15645, Cerv" "IPR004181:Zinc finger, MIZ-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR026846:E3 SUMO-protein ligase Nse2 (Mms21)" CG15645 27-Aug-18 DroID_v2018_08 Drer\nsmce2 Scer\MMS21 Cele\ZK1248.11 - Mmus\Nsmce2 Hsap\NSMCE2 viable FBgn0036576 CG5151 - http://flybase.org/reports/FBgn0036576 protein_coding_gene - - - CG5151 - CG5151 27-Aug-18 DroID_v2018_08 Drer\ldlrad4b - - - Mmus\Ldlrad4 Hsap\LDLRAD4 "viable,fertile" FBgn0016855 l(1)N36 lethal (1) N36 http://flybase.org/reports/FBgn0016855 - gene - - - "l(1)N36, N36" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0027505 Rab3-GAP Rab3 GTPase activating protein http://flybase.org/reports/FBgn0027505 - protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from sequence or structural similarity with UniProtKB:Q5U1Z0 Rab guanyl-nucleotide exchange factor activity ; GO:0017112 | inferred from biological aspect of ancestor with PANTHER:PTN000279859 enzyme regulator activity ; GO:0030234 | inferred from sequence or structural similarity with UniProtKB:Q5U1Z0 intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000279859 regulation of synaptic activity ; GO:0060025 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype regulation of GTPase activity ; GO:0043087 | inferred from biological aspect of ancestor with PANTHER:PTN000279859 neurotransmitter secretion ; GO:0007269 | non-traceable author statement vesicle-mediated transport ; GO:0016192 | non-traceable author statement regulation of GTPase activity ; GO:0043087 | inferred from sequence or structural similarity with UniProtKB:Q5U1Z0 synaptic vesicle ; GO:0008021 | non-traceable author statement "BcDNA:LD23336, CG7061, rab3-GAP, Rab3-GAP" "IPR032839:Rab3-GAP regulatory subunit, N-terminal, IPR029257:Rab3GAP regulatory subunit, C-terminal, IPR026059:Rab3-GAP regulatory subunit" CG7061 27-Aug-18 DroID_v2018_08 Drer\rab3gap2 - Cele\rbg-2 Xtro\rab3gap2 Mmus\Rab3gap2 Hsap\RAB3GAP2 "neurophysiology defective,chemical sensitive,cell migration defective,viable" border follicle cell FBgn0037981 Spt3 Spt3 http://flybase.org/reports/FBgn0037981 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 histone acetyltransferase activity ; GO:0004402 | contributes_to inferred from direct assay histone H3 acetylation ; GO:0043966 | inferred from direct assay transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:11466 inferred from sequence or structural similarity with SGD:S000002800 SAGA complex ; GO:0000124 | inferred from direct assay histone acetyltransferase complex ; GO:0000123 | inferred from sequence or structural similarity with HGNC:11466 inferred from sequence or structural similarity with SGD:S000002800 nucleus ; GO:0005634 | inferred from direct assay transcription factor TFIID complex ; GO:0005669 | inferred from sequence or structural similarity with HGNC:11466 inferred from sequence or structural similarity with SGD:S000002800 "dSpt3, TFIID, SPT3, CG3169, Spt3" "IPR003195:Transcription initiation factor IID, subunit 13, IPR009072:Histone-fold" CG3169 27-Aug-18 DroID_v2018_08 Drer\supt3h "Scer\TAF13, Scer\SPT3" Cele\taf-13 "Xtro\supt3h, Xtro\taf13" "Mmus\Taf13, Mmus\Supt3" "Hsap\TAF13, Hsap\SUPT3H" viable FBgn0005742 l(1)TK234 lethal (1) TK234 http://flybase.org/reports/FBgn0005742 - gene - - - "l234, l(1)TK234" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" eye FBgn0267533 asRNA:CR45873 - http://flybase.org/reports/FBgn0267533 non_protein_coding_gene - - - CR45873 - CR45873 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033069 eIF3f2 eukaryotic translation initiation factor 3 subunit f2 http://flybase.org/reports/FBgn0033069 protein_coding_gene translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity translation initiation factor activity ; GO:0003743 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000056988 translation initiation factor binding ; GO:0031369 | inferred from biological aspect of ancestor with PANTHER:PTN000056988 thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from sequence or structural similarity with HGNC:3275 protein deubiquitination ; GO:0016579 | inferred from sequence or structural similarity with HGNC:3275 translational initiation ; GO:0006413 | inferred from sequence or structural similarity translational initiation ; GO:0006413 | inferred from biological aspect of ancestor with PANTHER:PTN000056988 "eukaryotic translation initiation factor 3 complex, eIF3m ; GO:0071541 | inferred from biological aspect of ancestor with PANTHER:PTN000056988 eukaryotic translation initiation factor 3 complex ; GO:0005852 | inferred from sequence or structural similarity" "eIF3-S5, CG8335, eIF3f, eIF3f2" "IPR000555:JAB1/MPN/MOV34 metalloenzyme domain, IPR024969:Rpn11/EIF3F, C-terminal, IPR027531:Eukaryotic translation initiation factor 3 subunit F" CG8335 27-Aug-18 DroID_v2018_08 Drer\eif3f Scer\RPN8 Cele\eif-3.F Xtro\eif3f Mmus\Eif3f Hsap\EIF3F viable FBgn0040124 l(2)23CDd lethal (2) 23CDd http://flybase.org/reports/FBgn0040124 gene - - - l(2)23CDd - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0000883 fs(1)M81 female sterile (1) M81 http://flybase.org/reports/FBgn0000883 - gene - - - fs(1)M81 - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive,lethal,maternal effect" FBgn0264262 lncRNA:CR43762 - http://flybase.org/reports/FBgn0264262 non_protein_coding_gene - - - CR43762 - CR43762 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033682 CG18344 - http://flybase.org/reports/FBgn0033682 protein_coding_gene - - - CG18344 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0003588 Su(var)2-8 Suppressor of variegation 2-8 http://flybase.org/reports/FBgn0003588 - gene - - - "Su-var(2)8, Su-var, Su2, Su(var)2-8" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,suppressor of variegation,dominant" FBgn0004164 fs(2)sun female sterile (2) supernova http://flybase.org/reports/FBgn0004164 - gene - - - "sun, fs(2)sun" - - 27-Aug-18 DroID_v2018_08 - - - - - - female sterile FBgn0015036 Cyp4ae1 Cytochrome P450-4ae1 http://flybase.org/reports/FBgn0015036 FBgn0014088 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "Cypae1, 4ae1, EG:152A3.6, CG10755, CYP4E4, P450, P-450, TcD20, I, anon-2Ea, Cyp4e4, Cyp4ae1" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG10755 27-Aug-18 DroID_v2018_08 "Drer\cyp19a1a, Drer\cyp46a1.2, Drer\cyp19a1b, Drer\cyp4t8, Drer\cyp46a1.1, Drer\cyp20a1, Drer\cyp3c1, Drer\cyp46a1.4, Drer\cyp46a1.3, Drer\cyp4f3, Drer\cyp3c4, Drer\LOC100329425, Drer\cyp4v8, Drer\cyp26b1, Drer\cyp3c3, Drer\cyp3c2, Drer\cyp26a1, Drer\cyp4v7, Drer\cyp3a65, Drer\cyp26c1" "Scer\DIT2, Scer\ERG5" "Cele\cyp-32B1, Cele\cyp-37B1, Cele\cyp-13A1, Cele\cyp-29A4, Cele\cyp-37A1, Cele\cyp-25A4, Cele\cyp-13A10, Cele\cyp-13A12, Cele\cyp-25A2, Cele\cyp-13A11, Cele\cyp-29A3, Cele\cyp-13A3, Cele\cyp-13A8, Cele\cyp-13A5, Cele\cyp-13A7, Cele\cyp-31A5, Cele\cyp-13A4, Cele\cyp-25A3, Cele\cyp-42A1, Cele\cyp-25A1, Cele\cyp-29A2, Cele\cyp-31A3, Cele\cyp-31A2, Cele\cyp-32A1" "Xtro\cyp26b1, Xtro\LOC100488227, Xtro\mgc108213, Xtro\cyp4b1, Xtro\cyp20a1, Xtro\cyp26a1, Xtro\LOC100487918, Xtro\cyp4v2, Xtro\cyp26c1, Xtro\cyp4b1.2, Xtro\cyp4f2, Xtro\cyp19a1, Xtro\cyp4f22, Xtro\cyp2j2" "Mmus\Cyp4a14, Mmus\Cyp4f37, Mmus\Cyp4a10, Mmus\Cyp4f14, Mmus\Cyp4b1, Mmus\Cyp3a57, Mmus\Cyp4f39, Mmus\Cyp4f40, Mmus\Cyp20a1, Mmus\Cyp4v3, Mmus\Cyp4a12a, Mmus\Cyp3a41b, Mmus\Cyp3a11, Mmus\Cyp4a31, Mmus\Cyp4f15, Mmus\Cyp4f16, Mmus\Cyp3a41a, Mmus\Cyp3a13, Mmus\Cyp3a25, Mmus\Cyp26b1, Mmus\Cyp4a32, Mmus\Cyp3a59, Mmus\Cyp26c1, Mmus\Cyp19a1, Mmus\Cyp4f18, Mmus\Cyp3a16, Mmus\Cyp46a1, Mmus\Cyp26a1, Mmus\Cyp4a12b, Mmus\Cyp4a29, Mmus\Cyp3a44, Mmus\Cyp4f13, Mmus\Cyp4f17, Mmus\Cyp4x1, Mmus\Cyp4a30b" "Hsap\CYP4Z1, Hsap\CYP4V2, Hsap\CYP3A4, Hsap\CYP4F11, Hsap\CYP4F2, Hsap\CYP26B1, Hsap\CYP26C1, Hsap\CYP20A1, Hsap\CYP4F8, Hsap\CYP4F22, Hsap\CYP26A1, Hsap\CYP4F12, Hsap\CYP4X1, Hsap\CYP46A1, Hsap\CYP4F3, Hsap\CYP4B1, Hsap\CYP3A43, Hsap\CYP4A11, Hsap\CYP3A5, Hsap\CYP3A7, Hsap\CYP19A1, Hsap\CYP4A22" viable FBgn0040211 hgo "homogentisate 1,2-dioxygenase" http://flybase.org/reports/FBgn0040211 protein_coding_gene "homogentisate 1,2-dioxygenase activity ; GO:0004411 | inferred from electronic annotation with InterPro:IPR005708" oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005708 L-phenylalanine catabolic process ; GO:0006559 | inferred from electronic annotation with InterPro:IPR005708 tyrosine metabolic process ; GO:0006570 | inferred from electronic annotation with InterPro:IPR005708 - "CG4779, hgo" "IPR005708:Homogentisate 1,2-dioxygenase, IPR011051:RmlC-like cupin domain, IPR014710:RmlC-like jelly roll fold" CG4779 27-Aug-18 DroID_v2018_08 Drer\hgd - Cele\hgo-1 Xtro\hgd Mmus\Hgd Hsap\HGD viable FBgn0038157 CG12538 - http://flybase.org/reports/FBgn0038157 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12538 - CG12538 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC14527 E 0.046437574 0.110228914 -0.08017396 2.479050407 0.728833408 0.372081463 FBgn0085190 CG34161 - http://flybase.org/reports/FBgn0085190 protein_coding_gene acylphosphatase activity ; GO:0003998 | inferred from biological aspect of ancestor with PANTHER:PTN000003030 - - CG34161 "IPR017968:Acylphosphatase, conserved site, IPR001792:Acylphosphatase-like domain, IPR020456:Acylphosphatase" CG34161 27-Aug-18 DroID_v2018_08 "Drer\acyp1, Drer\acyp2" - - "Xtro\acyp1, Xtro\acyp2" "Mmus\Acyp2, Mmus\Acyp1" "Hsap\ACYP1, Hsap\ACYP2" FBgn0069111 mus219 mutagen-sensitive 219 http://flybase.org/reports/FBgn0069111 gene - - - mus219 - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,chemical sensitive" FBgn0085244 CG34215 - http://flybase.org/reports/FBgn0085244 protein_coding_gene - defense response to virus ; GO:0051607 | inferred from biological aspect of ancestor with PANTHER:PTN002219240 - CG34215 IPR029277:Single domain Von Willebrand factor type C domain CG34215 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000641 fc faulty chaetae http://flybase.org/reports/FBgn0000641 - gene - - - fc - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,viable,fertile,recessive" "macrochaeta,scutellar bristle" FBgn0261728 EC666 - http://flybase.org/reports/FBgn0261728 gene - - - EC666 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,some die during third instar larval stage" FBgn0030132 CG12067 - http://flybase.org/reports/FBgn0030132 protein_coding_gene - - - CG12067 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0023474 alm almond http://flybase.org/reports/FBgn0023474 - gene - - - alm - - 27-Aug-18 DroID_v2018_08 - - - - - - visible pigment cell FBgn0039740 ZIPIC Zinc-finger protein interacting with CP190 http://flybase.org/reports/FBgn0039740 protein_coding_gene chromatin binding ; GO:0003682 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with Cp190 sequence-specific DNA binding ; GO:0043565 | inferred from direct assay DNA binding ; GO:0003677 | inferred from direct assay chromatin insulator sequence binding ; GO:0043035 | inferred from direct assay "regulation of transcription, DNA-templated ; GO:0006355 | inferred from direct assay" polytene chromosome ; GO:0005700 | inferred from direct assay "ZIPIC, CG7928" "IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG7928 27-Aug-18 DroID_v2018_08 - Scer\AZF1 Cele\Y55F3AM.14 "Xtro\prdm15, Xtro\znf654" Mmus\Zfp654 "Hsap\ZNF654, Hsap\CTCFL" "partially lethal - majority die,some die during pupal stage" FBgn0266689 lncRNA:CR45179 - http://flybase.org/reports/FBgn0266689 non_protein_coding_gene - - - CR45179 - CR45179 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262149 lncRNA:CR42875 - http://flybase.org/reports/FBgn0262149 non_protein_coding_gene - - - CR42875 - CR42875 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0250850 rig rigor mortis http://flybase.org/reports/FBgn0250850 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P16375 inferred from physical interaction with UniProtKB:P20153 inferred from physical interaction with UniProtKB:P31396 inferred from physical interaction with UniProtKB:P34021 inferred from physical interaction with UniProtKB:Q05192 "molting cycle, chitin-based cuticle ; GO:0007591 | inferred from mutant phenotype adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype flight behavior ; GO:0007629 | inferred from mutant phenotype epithelium development ; GO:0060429 | inferred from mutant phenotype response to ecdysone ; GO:0035075 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype spliceosomal snRNP assembly ; GO:0000387 | inferred from sequence or structural similarity with UniProtKB:Q8TEQ6" nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay cytoplasmic U snRNP body ; GO:0071254 | inferred from direct assay SMN complex ; GO:0032797 | inferred from genetic interaction with Gem3 "Rig, CG30149, l(2)05056, CG13440, CG11171, rig, anon-SAGE:Wang-132, Gem5" "IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR019775:WD40 repeat, conserved site, IPR024977:Anaphase-promoting complex subunit 4, WD40 domain" CG30149 27-Aug-18 DroID_v2018_08 "Drer\grwd1, Drer\gemin5" "Scer\RRB1, Scer\WTM1, Scer\WTM2, Scer\UME1" Cele\Y54H5A.1 Xtro\gemin5 "Mmus\Gemin5, Mmus\Grwd1" "Hsap\GEMIN5, Hsap\GRWD1" FBgn0259402 EP-501 - http://flybase.org/reports/FBgn0259402 gene - - - EP-501 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible wing vein FBgn0066359 l(2)199 lethal (2) 199 http://flybase.org/reports/FBgn0066359 gene - - - l(2)199 - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0047351 CG31468 - http://flybase.org/reports/FBgn0047351 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs18e02, NEST:bs21c04, NEST:bs34b06, NEST:bs12h04, BcDNA:AT08725, CG31468, Tes37" IPR010736:Sperm-tail PG-rich repeat CG31468 27-Aug-18 DroID_v2018_08 "Drer\odf3l2, Drer\zgc:110183" - - - "Mmus\Odf3l1, Mmus\Odf3l2" "Hsap\ODF3L2, Hsap\ODF3L1" viable FBgn0041233 Gr59e Gustatory receptor 59e http://flybase.org/reports/FBgn0041233 protein_coding_gene taste receptor activity ; GO:0008527 | non-traceable author statement sensory perception of taste ; GO:0050909 | inferred from electronic annotation with InterPro:IPR013604 detection of chemical stimulus involved in sensory perception of taste ; GO:0050912 | non-traceable author statement integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 integral component of membrane ; GO:0016021 | non-traceable author statement "Gr59E2, CG15872, 59E2, 59E.2, GR59E.2, CG33151, Gr59e, GR59e, Gr59E" IPR013604:7TM chemoreceptor CG33151 27-Aug-18 DroID_v2018_08 "Drer\asic1a, Drer\asic1c, Drer\asic4a, Drer\asic4b, Drer\asic1b, Drer\asic2" - "Cele\srt-26, Cele\srt-30, Cele\srt-53, Cele\srt-27, Cele\srt-28" "Xtro\scnn1d, Xtro\scnn1a, Xtro\asic4, Xtro\scnn1g, Xtro\asic1, Xtro\asic5, Xtro\scnn1b" "Mmus\Scnn1b, Mmus\Asic5, Mmus\Scnn1a, Mmus\Asic4, Mmus\Scnn1g, Mmus\Asic3, Mmus\Asic2, Mmus\Asic1" "Hsap\ASIC5, Hsap\ASIC2, Hsap\SCNN1G, Hsap\ASIC4, Hsap\ASIC1, Hsap\ASIC3, Hsap\SCNN1A, Hsap\SCNN1B, Hsap\SCNN1D" viable FBgn0022109 l(2)k07001 lethal (2) k07001 http://flybase.org/reports/FBgn0022109 - gene - - - l(2)k07001 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0086296 bleb bleb http://flybase.org/reports/FBgn0086296 gene - dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype - bleb - - 27-Aug-18 DroID_v2018_08 - - - - - - "neuroanatomy defective,lethal,recessive" dendrite | larval stage FBgn0044061 GTD74-198 GTD74-198 http://flybase.org/reports/FBgn0044061 gene - - - GTD74-198 - - 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0023054 l(1)3ABb lethal (1) 3ABb http://flybase.org/reports/FBgn0023054 - gene - - - "1200C6, l(1)3ABb" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0266343 so::Optix - http://flybase.org/reports/FBgn0266343 engineered_fusion_gene - - - so::Optix - - 27-Aug-18 DroID_v2018_08 - - - - - - "eye,ectopic" FBgn0283501 lncRNA:CR46115 - http://flybase.org/reports/FBgn0283501 non_protein_coding_gene - - - "CR46115, CR45992" - CR46115 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037275 CG14655 - http://flybase.org/reports/FBgn0037275 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - CG14655 "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG14655 27-Aug-18 DroID_v2018_08 "Drer\znf281a, Drer\bcl6b, Drer\LOC100537687, Drer\bcl6a, Drer\prdm13, Drer\bcl6ab" "Scer\YPR015C, Scer\CMR3" "Cele\zag-1, Cele\ztf-30, Cele\ztf-16, Cele\Y55F3AM.14" "Xtro\znf142, Xtro\bcl6" "Mmus\Bcl6, Mmus\Ikzf5, Mmus\Prdm13, Mmus\Bcl6b" "Hsap\BCL6B, Hsap\BCL6, Hsap\PRDM13, Hsap\ZBTB16, Hsap\ZNF81, Hsap\TIGD1, Hsap\IKZF5" viable FBgn0028637 ifm(2)RU5 indirect flight muscle (2) RU5 http://flybase.org/reports/FBgn0028637 gene molecular_function ; GO:0003674 | no biological data available muscle organ development ; GO:0007517 | inferred from mutant phenotype polytene chromosome puff ; GO:0005703 | inferred from direct assay ifm(2)RU5 - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive,flight defective,sterile,viable" "indirect flight muscle,indirect flight muscle & myofibril,wing,dorsal medial muscle" FBgn0011133 l(1)Q208 lethal (1) Q208 http://flybase.org/reports/FBgn0011133 FBgn0010210 gene - - - l(1)Q208 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0265198 lncRNA:CR44258 - http://flybase.org/reports/FBgn0265198 non_protein_coding_gene - - - CR44258 - CR44258 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0013656 ms(2)neo1 male sterile (2) neo1 http://flybase.org/reports/FBgn0013656 - gene - - - ms(2)neo1 - - 27-Aug-18 DroID_v2018_08 - - - - - - male sterile FBgn0264716 lncRNA:CR43984 - http://flybase.org/reports/FBgn0264716 non_protein_coding_gene - - - CR43984 - CR43984 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065153 l(3)SH064 lethal (3) SH064 http://flybase.org/reports/FBgn0065153 gene - - - "l(3)SH064, l(2)SH3 064" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0000983 fs(2)HO308 female sterile (2) HO308 http://flybase.org/reports/FBgn0000983 - gene - - - "fs(2)308A, fs(2)HO308" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005416 l(1)adl5 lethal (1) adl5 http://flybase.org/reports/FBgn0005416 - gene - - - "l(1)adl-5, l(1)adl5" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,heat sensitive,short lived" FBgn0039051 CG17109 - http://flybase.org/reports/FBgn0039051 protein_coding_gene aminoacylase activity ; GO:0004046 | inferred from electronic annotation with InterPro:IPR010159 cellular amino acid metabolic process ; GO:0006520 | inferred from electronic annotation with InterPro:IPR010159 cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR010159 CG17109 "IPR002933:Peptidase M20, IPR010159:N-acyl-L-amino-acid amidohydrolase, IPR011650:Peptidase M20, dimerisation domain" CG17109 27-Aug-18 DroID_v2018_08 "Drer\acy1, Drer\LOC100001620, Drer\pm20d1.2, Drer\pm20d1.1" Scer\CPS1 "Cele\C06A6.4, Cele\C10C5.4, Cele\C10C5.3, Cele\C10C5.5" "Xtro\acy1.1, Xtro\pm20d1" "Mmus\Pm20d1, Mmus\Acy1, Mmus\Cndp1" "Hsap\PM20D1, Hsap\CNDP1, Hsap\ACY1, Hsap\ABHD14A, Hsap\ABHD14A-ACY1" "partially lethal - majority die,some die during pupal stage,viable" FBgn0031054 Ssu72 Ssu72 CTD phosphatase http://flybase.org/reports/FBgn0031054 protein_coding_gene CTD phosphatase activity ; GO:0008420 | inferred from direct assay phosphatase activity ; GO:0016791 | inferred from direct assay termination of RNA polymerase II transcription ; GO:0006369 | inferred from biological aspect of ancestor with PANTHER:PTN000463875 mRNA polyadenylation ; GO:0006378 | inferred from biological aspect of ancestor with PANTHER:PTN000463875 protein dephosphorylation ; GO:0006470 | inferred from direct assay dephosphorylation of RNA polymerase II C-terminal domain ; GO:0070940 | inferred from direct assay mRNA 3'-end processing ; GO:0031124 | inferred from sequence or structural similarity with SGD:S000005166 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000005166 mRNA cleavage and polyadenylation specificity factor complex ; GO:0005847 | inferred from biological aspect of ancestor with PANTHER:PTN000463875 "BEST:CK01830, CG14216, Ssu72, dSsu72" IPR006811:RNA polymerase II subunit A CG14216 27-Aug-18 DroID_v2018_08 Drer\ssu72 Scer\SSU72 Cele\ssup-72 Xtro\ssu72 Mmus\Ssu72 Hsap\SSU72 "viable,visible,lethal,recessive" trichogen cell FBgn0001709 l(1)ESHS30 lethal (1) ESHS30 http://flybase.org/reports/FBgn0001709 - gene - - - l(1)ESHS30 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0086168 E(var)2-1 Enhancer of variegation 2-1 http://flybase.org/reports/FBgn0086168 gene - - - E(var)2-1 - - 27-Aug-18 DroID_v2018_08 - - - - - - "enhancer of variegation,dominant" FBgn0083036 snoRNA:Psi18S-525c snoRNA:Psi18S-525c http://flybase.org/reports/FBgn0083036 snoRNA_gene - - - "snoRNA:Psi18S-525c, psi18S-525c, CR34573" - CR34573 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038602 CG7126 - http://flybase.org/reports/FBgn0038602 protein_coding_gene - - - CG7126 - CG7126 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0277428 l(3)psg29 - http://flybase.org/reports/FBgn0277428 gene - - - "l(3)psg29, psg29" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030242 sofe sister of feo http://flybase.org/reports/FBgn0030242 protein_coding_gene microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR007145 signal transducer activity ; GO:0004871 | inferred from electronic annotation with InterPro:IPR015898 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR015898 microtubule cytoskeleton organization ; GO:0000226 | inferred from electronic annotation with InterPro:IPR007145 cytokinesis ; GO:0000910 | inferred from electronic annotation with InterPro:IPR007145 heterotrimeric G-protein complex ; GO:0005834 | inferred from electronic annotation with InterPro:IPR015898 "CG1655, sofe" "IPR007145:Microtubule-associated protein, MAP65/Ase1/PRC1, IPR015898:G-protein gamma-like domain" CG1655 27-Aug-18 DroID_v2018_08 "Drer\zgc:86764, Drer\prc1a, Drer\prc1b" Scer\ASE1 Cele\spd-1 "Xtro\prc1.2, Xtro\jakmip3, Xtro\prc1" Mmus\Prc1 Hsap\PRC1 "viable,fertile" FBgn0262631 lncRNA:CR43148 - http://flybase.org/reports/FBgn0262631 non_protein_coding_gene - - - CR43148 - CR43148 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0050122 CG30122 - http://flybase.org/reports/FBgn0050122 protein_coding_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011" precatalytic spliceosome ; GO:0071011 | inferred from direct assay "LD11002, CG18610, CG5477, CG30122, SAF-A" "IPR003034:SAP domain, IPR003877:SPRY domain, IPR013320:Concanavalin A-like lectin/glucanase domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR001870:B30.2/SPRY domain" CG30122 27-Aug-18 DroID_v2018_08 "Drer\hnrnpul1l, Drer\hnrnpub, Drer\si:ch211-107m4.1, Drer\hnrnpua, Drer\hnrnpul1" - "Cele\tofu-2, Cele\Y41E3.11, Cele\acin-1" "Xtro\hnrnpul2, Xtro\hnrnpu, Xtro\rnf123, Xtro\hnrnpul1" "Mmus\Hnrnpul2, Mmus\Rnf123, Mmus\Hnrnpu, Mmus\Hnrnpul1" "Hsap\RNF123, Hsap\HNRNPUL1, Hsap\HNRNPU, Hsap\HNRNPUL2" viable FBgn0065908 l(2)SH0185 lethal (2) SH0185 http://flybase.org/reports/FBgn0065908 gene - - - "l(2)SH0185, l(2)SH2 0185" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0039670 CG7567 - http://flybase.org/reports/FBgn0039670 protein_coding_gene - - - "BcDNA:RE47447, CG7567" IPR007931:Protein of unknown function DUF725 CG7567 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible" trichogen cell FBgn0025631 moody moody http://flybase.org/reports/FBgn0025631 FBgn0041254 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from electronic annotation with InterPro:IPR000276 G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR000276 cortical actin cytoskeleton organization ; GO:0030866 | inferred from mutant phenotype establishment of glial blood-brain barrier ; GO:0060857 | inferred from mutant phenotype behavioral response to nicotine ; GO:0035095 | inferred from mutant phenotype septate junction assembly ; GO:0019991 | inferred from mutant phenotype behavioral response to cocaine ; GO:0048148 | inferred from mutant phenotype G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype ventral cord development ; GO:0007419 | inferred from mutant phenotype "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR017452 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity plasma membrane ; GO:0005886 | inferred from direct assay pleated septate junction ; GO:0005919 | inferred from direct assay" "CG4322, 1631, EG:22E5.11, EP1631, moody, Moody" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG4322 27-Aug-18 DroID_v2018_08 "Drer\npy8br, Drer\npy2rl, Drer\prlhr2b, Drer\npy1r, Drer\gpr19, Drer\tmtops2a, Drer\mchr1a, Drer\npy2r, Drer\npy8ar, Drer\mtnr1ba, Drer\mtnr1ab, Drer\gpr88, Drer\prokr1a, Drer\mchr1b, Drer\tmtops2b, Drer\mtnr1c, Drer\prlhr2a, Drer\gpr84, Drer\npy4r, Drer\mtnr1bb, Drer\mtnr1aa, Drer\prokr1b" - "Cele\npr-10, Cele\npr-17, Cele\npr-6" "Xtro\LOC100490436, Xtro\gpr84" "Mmus\Mchr1, Mmus\Npy1r, Mmus\Gpr84, Mmus\Npy6r, Mmus\Npy5r, Mmus\Npy2r, Mmus\Mtnr1b, Mmus\Mtnr1a, Mmus\Npy4r, Mmus\Prokr2, Mmus\Gpr19, Mmus\Prokr1, Mmus\Gpr88, Mmus\Prlhr" "Hsap\MCHR1, Hsap\MTNR1A, Hsap\NPY5R, Hsap\PROKR1, Hsap\PRLHR, Hsap\NPY2R, Hsap\NPY1R, Hsap\GPR88, Hsap\MTNR1B, Hsap\NPY4R, Hsap\GPR84, Hsap\GPR19, Hsap\GPR50, Hsap\PROKR2" "lethal,neuroanatomy defective,behavior defective,viable,chemosensitive behavior defective,partially lethal - majority die,male,recessive,some die during larval stage" "germline cell,ectopic,maternal effect,germline cell | embryonic stage" FBgn0043534 Obp57b Odorant-binding protein 57b http://flybase.org/reports/FBgn0043534 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with UniProtKB:P34174 transport ; GO:0006810 | non-traceable author statement sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush extracellular region ; GO:0005576 | inferred from sequence model "57b, Obp-e, anon-AE003792.2, CG30142, Obp57b, DmelObp57b, obp57b" IPR006170:Pheromone/general odorant binding protein CG30142 27-Aug-18 DroID_v2018_08 - - - - - - DRSC21914 E -0.231921409 -0.137454033 1.047696293 1.768157677 -0.578103034 0.684722944 FBgn0039966 Rab21 Rab21 http://flybase.org/reports/FBgn0039966 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR005225 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11 phosphatidylinositol 3-kinase catalytic subunit binding ; GO:0036313 | inferred from physical interaction with Pi3K68D protein binding ; GO:0005515 | inferred from physical interaction with Sbf" Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 positive regulation of autophagosome maturation ; GO:1901098 | inferred from mutant phenotype cortical actin cytoskeleton organization ; GO:0030866 | inferred from mutant phenotype regulation of endocytosis ; GO:0030100 | inferred from biological aspect of ancestor with PANTHER:PTN000634504 vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 SNARE complex ; GO:0031201 | colocalizes_with inferred from physical interaction with Vamp7 synapse ; GO:0045202 | inferred from direct assay vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 recycling endosome ; GO:0055037 | inferred from direct assay early endosome ; GO:0005769 | inferred from direct assay "CG17515, AAF45341, DmRab21, CG40304, anon-EST:Posey237, Rab21, rab21, Q7PLE8" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG17515 27-Aug-18 DroID_v2018_08 "Drer\zgc:154045, Drer\rab22a, Drer\rab31, Drer\rab5c, Drer\rab5ab" "Scer\YPT10, Scer\VPS21, Scer\YPT52, Scer\YPT53" "Cele\rab-21, Cele\rab-5, Cele\C52B11.5, Cele\C56E6.2" "Xtro\rab5a, Xtro\rab5b, Xtro\rab22a, Xtro\rab21, Xtro\mras, Xtro\rab5c" "Mmus\Rab21, Mmus\Rab22a, Mmus\Rab31, Mmus\Rab5a, Mmus\Rab5b, Mmus\Rab5c" "Hsap\RAB5C, Hsap\RAB5A, Hsap\RAB5B, Hsap\RAB21, Hsap\RAB31, Hsap\RAB22A" macrophage DRSC20968 E 0.320072109 -0.03818283 2.295535153 0.356380935 -0.055804499 0.134998578 FBgn0259571 GG01341 - http://flybase.org/reports/FBgn0259571 gene - - - GG01341 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "leg,unguis,antennal segment,arista,wing margin,macrochaeta,mesothoracic tergum,scutellum" FBgn0003673 tc tiny chaetae http://flybase.org/reports/FBgn0003673 - gene - - - tc - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive,viable,fertile,lethal" macrochaeta FBgn0060437 l(3)S125011 lethal (3) S125011 http://flybase.org/reports/FBgn0060437 gene - - - "1250/11, l(3)S125011" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0014072 TART-element\pol TART-open reading frame 2 http://flybase.org/reports/FBgn0014072 - transposable_element_gene - - - "RT, ORF2, TART-element\ORF2, TART-repeat\ORF2, TART-element\pol, TART ORF2, TART-RT" "IPR000477:Reverse transcriptase domain, IPR005135:Endonuclease/exonuclease/phosphatase" - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004774 l(3)91Cd lethal (3) 91Cd http://flybase.org/reports/FBgn0004774 - gene - - - "l(3)CR3, l(3)91Cd" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0039039 lmd lame duck http://flybase.org/reports/FBgn0039039 protein_coding_gene "nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with UniProt:Q61602 inferred from sequence or structural similarity with UniProtKB:P10070 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay inferred from mutant phenotype" "muscle organ development ; GO:0007517 | inferred from mutant phenotype myoblast fusion ; GO:0007520 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from sequence or structural similarity with UniProt:Q61602 inferred from sequence or structural similarity with UniProtKB:P10070 somatic muscle development ; GO:0007525 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype skeletal muscle tissue development ; GO:0007519 | inferred from mutant phenotype muscle organ development ; GO:0007517 | traceable author statement regulation of hormone levels ; GO:0010817 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "minc, gfl, Lmd, CG4677, K, anon-EST:CL2d4, lmd, LMD" "IPR013087:Zinc finger C2H2-type, IPR011990:Tetratricopeptide-like helical domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG4677 27-Aug-18 DroID_v2018_08 "Drer\klf9, Drer\glis2b, Drer\aaas, Drer\glis3, Drer\LOC100333406, Drer\glis2a" Scer\MIG2 "Cele\tra-1, Cele\M03D4.4" "Xtro\glis3, Xtro\glis2, Xtro\aaas" "Mmus\Glis3, Mmus\Glis1, Mmus\Gli2, Mmus\Gli3, Mmus\Aaas, Mmus\Gli1, Mmus\Glis2" "Hsap\GLI1, Hsap\GLIS1, Hsap\GLI2, Hsap\AAAS, Hsap\GLIS3, Hsap\GLI3, Hsap\GLIS2" embryonic stage | late mesoderm

"lethal,viable,visible" "embryonic somatic muscle,presumptive embryonic/larval muscle system,A1-7 dorsal acute muscle 1,embryonic/larval pericardial cell,supernumerary,muscle founder cell,embryonic myoblast,pharyngeal muscle,embryonic visceral muscle,trichogen cell" FBgn0015463 l(2)37Dk lethal (2) 37Dk http://flybase.org/reports/FBgn0015463 - gene - - - "l(2)E144,M, l(2)37Dk" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0037737 Pnn Pinin http://flybase.org/reports/FBgn0037737 protein_coding_gene - "cell adhesion ; GO:0007155 | inferred from biological aspect of ancestor with PANTHER:PTN000295178 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013" exon-exon junction complex ; GO:0035145 | inferred from biological aspect of ancestor with PANTHER:PTN000295178 cell-cell junction ; GO:0005911 | inferred from biological aspect of ancestor with PANTHER:PTN000295178 precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "CG8383, Pnn, dPnn, FBgn0037737, Pinin" IPR006786:Pinin/SDK/MemA protein CG8383 27-Aug-18 DroID_v2018_08 Drer\pnn - Cele\R186.7 Xtro\pnn Mmus\Pnn Hsap\PNN viable FBgn0260316 GSd479 - http://flybase.org/reports/FBgn0260316 gene - - - GSd479 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0053811 His-Psi:CR33811 His-Psi:CR33811 http://flybase.org/reports/FBgn0053811 pseudogene_attribute - - - "CR33811, His-Psi:CR33811" - CR33811 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0028024 l(3)S103616 lethal (3) S103616 http://flybase.org/reports/FBgn0028024 gene - - - "1036/16, l(3)S103616" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0003369 sg shortened wing http://flybase.org/reports/FBgn0003369 - gene - - - sg - - 27-Aug-18 DroID_v2018_08 - - - - - - "wing,wing vein" FBgn0261363 PPO3 Prophenoloxidase 3 http://flybase.org/reports/FBgn0261363 protein_coding_gene L-DOPA monooxygenase activity ; GO:0036263 | inferred from direct assay dopamine monooxygenase activity ; GO:0036264 | inferred from direct assay dopamine metabolic process ; GO:0042417 | inferred by curator from GO:0036264 melanotic encapsulation of foreign target ; GO:0035011 | inferred from genetic interaction with PPO2 extracellular region ; GO:0005576 | inferred from direct assay "Dox-A3, DmePPO3, CG2952, proPO59, PPO3, Pro-PO3, CG42640, ProPO59" "IPR014756:Immunoglobulin E-set, IPR013788:Hemocyanin/hexamerin, IPR005204:Hemocyanin, N-terminal, IPR000896:Hemocyanin/hexamerin middle domain, IPR008922:Uncharacterised domain, di-copper centre, IPR002227:Tyrosinase copper-binding domain, IPR005203:Hemocyanin, C-terminal" CG42640 27-Aug-18 DroID_v2018_08 Drer\tyrp1a - Cele\srj-53 - - - "melanotic mass phenotype,viable" melanotic mass FBgn0040567 CG12332 - http://flybase.org/reports/FBgn0040567 protein_coding_gene - - - CG12332 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040091 Ugt58Fa Ugt58Fa http://flybase.org/reports/FBgn0040091 protein_coding_gene glucuronosyltransferase activity ; GO:0015020 | inferred from sequence or structural similarity glucuronosyltransferase activity ; GO:0015020 | inferred from biological aspect of ancestor with PANTHER:PTN001376818 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR002213 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000230403 "CG4414, AC 004377A, Ugt58Fa, ugt58Fa" IPR002213:UDP-glucuronosyl/UDP-glucosyltransferase CG4414 27-Aug-18 DroID_v2018_08 "Drer\ugt2a6, Drer\ugt1b4, Drer\ugt5f1, Drer\ugt5g1, Drer\ugt2b6, Drer\ugt8, Drer\ugt1b2, Drer\ugt5c3, Drer\zgc:172315, Drer\ugt5b1, Drer\ugt5a1, Drer\ugt2b1, Drer\ugt5e1, Drer\ugt1b7, Drer\ugt1b3, Drer\ugt2a5, Drer\ugt5g2, Drer\ugt5b3, Drer\ugt1ab, Drer\ugt2b5, Drer\ugt2b3, Drer\ugt5b6, Drer\ugt5a4, Drer\ugt5b2, Drer\ugt5c1, Drer\ugt5c2, Drer\ugt5d1, Drer\ugt2a2, Drer\ugt5a5, Drer\ugt1b5, Drer\ugt5a2" Scer\ATG26 "Cele\ugt-25, Cele\ugt-3, Cele\ugt-30, Cele\ugt-28, Cele\ugt-6, Cele\ugt-9, Cele\ugt-1, Cele\ugt-46, Cele\C55H1.1, Cele\F10D2.8, Cele\ugt-11, Cele\ugt-36, Cele\ugt-5, Cele\ugt-14, Cele\ugt-22, Cele\ugt-47, Cele\ugt-29, Cele\ugt-40, Cele\ugt-55, Cele\ugt-49, Cele\ugt-60, Cele\ugt-2, Cele\H23N18.4, Cele\ugt-27, Cele\ugt-56, Cele\ugt-23, Cele\ugt-13, Cele\ugt-8, Cele\ugt-33, Cele\C03A7.13, Cele\K04A8.10, Cele\ugt-51, Cele\ugt-44, Cele\ugt-37, Cele\ugt-35, Cele\ugt-52, Cele\ugt-32, Cele\ugt-18, Cele\ugt-54, Cele\ugt-34, Cele\Y43D4A.2, Cele\ugt-24, Cele\ugt-43, Cele\ugt-15, Cele\ugt-17, Cele\C03A7.12, Cele\ugt-31, Cele\ugt-39, Cele\ugt-50, Cele\ugt-10, Cele\ugt-12, Cele\ugt-59, Cele\ugt-38, Cele\C23G10.6, Cele\ugt-19, Cele\ugt-16, Cele\ugt-4, Cele\ugt-48, Cele\ugt-53, Cele\ugt-58, Cele\ugt-7, Cele\ugt-41, Cele\ugt-45, Cele\ugt-61, Cele\ugt-21, Cele\ugt-20, Cele\ugt-42, Cele\ugt-26, Cele\ugt-62" "Xtro\ugt1a6, Xtro\ugt8, Xtro\ugt3a2, Xtro\ugt2b4, Xtro\ugt2a1" "Mmus\Ugt2b34, Mmus\Ugt8a, Mmus\Ugt2b36, Mmus\Ugt2b37, Mmus\Ugt3a1, Mmus\Ugt2b35, Mmus\Ugt2b1, Mmus\Ugt2b38, Mmus\Ugt1a9, Mmus\Ugt2a1, Mmus\Ugt1a2, Mmus\Ugt1a7c, Mmus\Ugt1a6b, Mmus\Ugt2b5, Mmus\Ugt1a5, Mmus\Ugt1a1, Mmus\Ugt3a2, Mmus\Ugt2a3" "Hsap\UGT3A2, Hsap\UGT1A7, Hsap\UGT2A3, Hsap\UGT2B15, Hsap\UGT2B4, Hsap\UGT1A9, Hsap\UGT2B11, Hsap\UGT8, Hsap\UGT2B10, Hsap\UGT1A6, Hsap\UGT1A1, Hsap\UGT2B17, Hsap\UGT1A5, Hsap\UGT1A10, Hsap\UGT1A4, Hsap\UGT3A1, Hsap\UGT1A3, Hsap\UGT2B7, Hsap\UGT1A8, Hsap\UGT2B28, Hsap\UGT2A2" viable DRSC04470 K 0.182574293 0.710379522 0.472020452 0.037192778 0.4394413 -1.689647062 FBgn0025163 l(2)38Eb lethal (2) 38Eb http://flybase.org/reports/FBgn0025163 - gene - - - l(2)38Eb - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0031614 CG11934 - http://flybase.org/reports/FBgn0031614 protein_coding_gene - - - CG11934 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037851 CG4664 - http://flybase.org/reports/FBgn0037851 protein_coding_gene - - - CG4664 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002003 l(2)36Bb lethal (2) 36Bb http://flybase.org/reports/FBgn0002003 - gene - - - "l(2L)HT-7, l(2)HT-7, l(2)36Bb" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0023162 Su(mg)1-6 Suppressor of modifier of gypsy 1-6 http://flybase.org/reports/FBgn0023162 - gene - - - Su(mg)1-6 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065532 l(2)SH1106 lethal (2) SH1106 http://flybase.org/reports/FBgn0065532 gene - - - "l(2)SH1106, l(2)SH2 1106" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0037137 Nopp140 Nopp140 http://flybase.org/reports/FBgn0037137 protein_coding_gene - ribosome biogenesis ; GO:0042254 | inferred from mutant phenotype rRNA 2'-O-methylation ; GO:0000451 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype nucleolus ; GO:0005730 | inferred from direct assay "CG7421, DmNopp140, Nopp140, nopp140, Nopp- 140" "IPR007718:SRP40, C-terminal, IPR017859:Treacle-like, Treacher Collins Syndrome" CG7421 27-Aug-18 DroID_v2018_08 Drer\nolc1 "Scer\SRP40, Scer\NSP1" "Cele\dao-5, Cele\cec-8" Xtro\nolc1 Mmus\Nolc1 Hsap\NOLC1 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0265988 mv mauve http://flybase.org/reports/FBgn0265988 protein_coding_gene - negative regulation of autophagosome size ; GO:0045771 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype endomembrane system ; GO:0012505 | inferred from biological aspect of ancestor with PANTHER:PTN000348578 "CG42863, mv, CG11814, CG5691" "IPR011993:PH domain-like, IPR023362:PH-BEACH domain, IPR000409:BEACH domain, IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR019775:WD40 repeat, conserved site" CG42863 27-Aug-18 DroID_v2018_08 "Drer\nbeaa, Drer\nsmaf, Drer\lrba, Drer\nbeal2, Drer\wdfy4, Drer\wdr81, Drer\wdfy3, Drer\nbeab" Scer\BPH1 Cele\lyst-1 "Xtro\wdfy3, Xtro\nsmaf, Xtro\lyst" "Mmus\Nbeal2, Mmus\Nsmaf, Mmus\Wdr81, Mmus\Nbea, Mmus\Wdfy3, Mmus\Lyst, Mmus\Lrba, Mmus\Wdfy4" "Hsap\NBEAL2, Hsap\NSMAF, Hsap\NBEA, Hsap\WDR81, Hsap\LYST, Hsap\WDFY3, Hsap\LRBA, Hsap\WDFY4" FBgn0250840 CG12907 - http://flybase.org/reports/FBgn0250840 protein_coding_gene - - - "CG12907, BcDNA:AT31822, anon-WO0140519.79, anon-SAGE:Wang-109" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034497 Mpcp1 - http://flybase.org/reports/FBgn0034497 protein_coding_gene phosphate ion transmembrane transporter activity ; GO:0015114 | inferred from biological aspect of ancestor with PANTHER:PTN000639943 phosphate ion transmembrane transporter activity ; GO:0015114 | inferred from sequence or structural similarity with UniProtKB:Q00325 mitochondrial transport ; GO:0006839 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 phosphate ion transport ; GO:0006817 | inferred from sequence or structural similarity with UniProtKB:Q00325 mitochondrial envelope ; GO:0005740 | inferred from sequence or structural similarity with UniProtKB:Q00325 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 CG9090 "IPR018108:Mitochondrial substrate/solute carrier, IPR023395:Mitochondrial carrier domain" CG9090 27-Aug-18 DroID_v2018_08 "Drer\slc25a3a, Drer\slc25a3b" "Scer\PIC2, Scer\MIR1" "Cele\F01G4.6, Cele\C33F10.12, Cele\C14C10.1, Cele\T05F1.8" Xtro\slc25a3 Mmus\Slc25a3 Hsap\SLC25A3 viable FBgn0002016 l(2)36Fi lethal (2) 36Fi http://flybase.org/reports/FBgn0002016 - gene - - - "l(2)E105, l(2)36Fi" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0020445 E23 Early gene at 23 http://flybase.org/reports/FBgn0020445 "FBgn0031524, FBgn0031525" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR017871 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from biological aspect of ancestor with PANTHER:PTN000443108" regulation of circadian rhythm ; GO:0042752 | inferred from mutant phenotype regulation of circadian rhythm ; GO:0042752 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000443108 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000443108 "CG15410, CG3327, E23" "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR013525:ABC-2 type transporter, IPR017871:ABC transporter, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG3327 27-Aug-18 DroID_v2018_08 "Drer\abcg5, Drer\abcg2b, Drer\abcg8, Drer\abcg2a, Drer\abcg4a, Drer\abcg1, Drer\abcg4b" "Scer\PDR10, Scer\ADP1, Scer\YOL075C" "Cele\wht-4, Cele\pmp-3" "Xtro\abcg8, Xtro\abcg5" "Mmus\Abcg4, Mmus\Abcd4, Mmus\Abcg3, Mmus\Abcg1, Mmus\Abcg5, Mmus\Abcg2, Mmus\Abcg8" "Hsap\ABCG8, Hsap\ABCG5, Hsap\ABCD4, Hsap\ABCG4, Hsap\ABCG1" "viable,locomotor rhythm defective,lethal,circadian rhythm defective" FBgn0021974 l(2)k09932 lethal (2) k09932 http://flybase.org/reports/FBgn0021974 - gene - - - l(2)k09932 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0003159 CG2841 - http://flybase.org/reports/FBgn0003159 FBgn0029614 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "EG:BACH48C10.5, CG2841, ptr" - CG2841 27-Aug-18 DroID_v2018_08 "Drer\cobll1a, Drer\cobll1b" - - - Mmus\Cobll1 Hsap\COBLL1 viable FBgn0259741 CG42395 - http://flybase.org/reports/FBgn0259741 protein_coding_gene - - - CG42395 IPR006696:Protein of unknown function DUF423 CG42395 27-Aug-18 DroID_v2018_08 "Drer\tmem256, Drer\rps29" - "Cele\Y106G6H.8, Cele\rps-29" "Xtro\rps29, Xtro\tmem256" "Mmus\Tmem256, Mmus\Rps29" "Hsap\RPS29, Hsap\TMEM256" FBgn0027315 l(1)G0090 lethal (1) G0090 http://flybase.org/reports/FBgn0027315 - gene - - - l(1)G0090 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0002161 l(2)Sp2b lethal (2) Sp2b http://flybase.org/reports/FBgn0002161 - gene - - - l(2)Sp2b - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0001991 Ca-alpha1D Ca[2+]-channel protein alpha[[1]] subunit D http://flybase.org/reports/FBgn0001991 FBgn0004881 protein_coding_gene voltage-gated calcium channel activity ; GO:0005245 | inferred from mutant phenotype high voltage-gated calcium channel activity ; GO:0008331 | inferred from biological aspect of ancestor with PANTHER:PTN000004694 voltage-gated calcium channel activity ; GO:0005245 | inferred from sequence or structural similarity voltage-gated calcium channel activity ; GO:0005245 | non-traceable author statement calcium-mediated signaling ; GO:0019722 | inferred from mutant phenotype membrane depolarization during action potential ; GO:0086010 | inferred from biological aspect of ancestor with PANTHER:PTN000004140 muscle contraction ; GO:0006936 | traceable author statement calcium ion transmembrane transport ; GO:0070588 | inferred from mutant phenotype neuron remodeling ; GO:0016322 | inferred from mutant phenotype epithelial fluid transport ; GO:0042045 | inferred from direct assay inferred from expression pattern calcium ion transport ; GO:0006816 | non-traceable author statement voltage-gated calcium channel complex ; GO:0005891 | non-traceable author statement voltage-gated calcium channel complex ; GO:0005891 | inferred from sequence or structural similarity apical plasma membrane ; GO:0016324 | inferred from direct assay basolateral plasma membrane ; GO:0016323 | inferred from direct assay voltage-gated calcium channel complex ; GO:0005891 | inferred from genetic interaction with cac "Ca-alpha1D, CG4894, Dmca1D, DmCa1D, alpha1D, BG:DS02795.1, Ca-a1D, Ca-_1D, Ca-alpha1, l(2)35Fa, DmCa1alpha1, alpha1, DroCa1, l35Fa, Ca-alpha[[1]]D, Caalpha1D, ca-alpha1D, cad, Ca_alpha1D, ca-alpha1d, caID, Ca1D" "IPR002077:Voltage-dependent calcium channel, alpha-1 subunit, IPR005446:Voltage-dependent calcium channel, L-type, alpha-1 subunit, IPR005821:Ion transport domain, IPR014873:Voltage-dependent calcium channel, alpha-1 subunit, IQ domain, IPR031649:Voltage-dependent L-type calcium channel, IQ-associated domain, IPR031688:Voltage-gated calcium channel subunit alpha, C-terminal" CG4894 27-Aug-18 DroID_v2018_08 "Drer\cacna1db, Drer\scn4ab, Drer\cacna1ab, Drer\cacna1c, Drer\cacna1fb, Drer\nalcn, Drer\scn4aa, Drer\cacna1bb, Drer\cacna1aa, Drer\cacna1eb, Drer\cacna1e, Drer\cacna1fa, Drer\scn8ab, Drer\scn1a, Drer\cacna1ba, Drer\cacna1sa, Drer\cacna1da, Drer\scn1lab, Drer\cacna1sb" Scer\CCH1 "Cele\nca-2, Cele\egl-19, Cele\unc-77, Cele\unc-2" "Xtro\scn5a, Xtro\cacna1a, Xtro\cacna1d, Xtro\scn4a, Xtro\cacna1f, Xtro\scn3a, Xtro\cacna1e, Xtro\cacna1s, Xtro\nalcn" "Mmus\Catsper2, Mmus\Scn8a, Mmus\Scn5a, Mmus\Scn3a, Mmus\Cacna1e, Mmus\Scn10a, Mmus\Cacna1a, Mmus\Cacna1b, Mmus\Nalcn, Mmus\Cacna1f, Mmus\Cacna1c, Mmus\Scn9a, Mmus\Scn11a, Mmus\Cacna1d, Mmus\Cacna1s" "Hsap\SCN10A, Hsap\CACNA1F, Hsap\CACNA1S, Hsap\CACNA1A, Hsap\SCN9A, Hsap\CACNA1D, Hsap\CACNA1B, Hsap\CACNA1C, Hsap\SCN8A, Hsap\SCN5A, Hsap\SCN11A, Hsap\SCN3A, Hsap\NALCN, Hsap\CACNA1E" " adult stage , pupal stage | late , embryonic stage | 9-12 hr , embryonic stage " " adult head

, embryonic nervous system

" "lethal,recessive,wild-type,neuroanatomy defective,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of embryonic stage,some die during embryonic stage" "wing,longitudinal connective,abdominal segmental nerve,NMJ bouton,neuromuscular junction,embryonic/larval tracheal system,embryonic/larval midgut,cephalopharyngeal skeleton,embryonic/larval dorsal vessel" FBgn0265380 asRNA:CR44321 - http://flybase.org/reports/FBgn0265380 non_protein_coding_gene - - - CR44321 - CR44321 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036851 CG14082 - http://flybase.org/reports/FBgn0036851 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14082 - CG14082 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0011320 l(3)j2A2 lethal (3) j2A2 http://flybase.org/reports/FBgn0011320 - gene - - - l(3)j2A2 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0025629 CG4045 - http://flybase.org/reports/FBgn0025629 - protein_coding_gene tRNA (guanine-N7-)-methyltransferase activity ; GO:0008176 | contributes_to inferred from sequence or structural similarity with UniProtKB:Q9UBP6 tRNA (guanine-N7-)-methyltransferase activity ; GO:0008176 | inferred from sequence or structural similarity with HGNC:7030 tRNA (guanine-N7-)-methyltransferase activity ; GO:0008176 | inferred from biological aspect of ancestor with PANTHER:PTN000602515 RNA (guanine-N7)-methylation ; GO:0036265 | inferred from biological aspect of ancestor with PANTHER:PTN000602515 RNA (guanine-N7)-methylation ; GO:0036265 | inferred from sequence or structural similarity with HGNC:7030 tRNA modification ; GO:0006400 | inferred from sequence or structural similarity with UniProtKB:Q9UBP6 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:7030 tRNA methyltransferase complex ; GO:0043527 | inferred from biological aspect of ancestor with PANTHER:PTN000602515 "EG:22E5.4, CG4045" "IPR003358:tRNA (guanine-N-7) methyltransferase, Trmb type, IPR025763:tRNA (guanine-N-7) methyltransferase catalytic subunit Trm8, eukaryote, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG4045 27-Aug-18 DroID_v2018_08 Drer\mettl1 Scer\TRM8 Cele\W02B12.10 Xtro\mettl1 Mmus\Mettl1 Hsap\METTL1 viable FBgn0050357 CG30357 - http://flybase.org/reports/FBgn0050357 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT27059, CG30357" "IPR011705:BTB/Kelch-associated, IPR011333:SKP1/BTB/POZ domain, IPR000210:BTB/POZ domain, IPR031750:Domain of unknown function DUF4734" CG30357 27-Aug-18 DroID_v2018_08 Drer\klhl41a - - - - Hsap\KLHL31 viable DRSC22472 K 0.291349218 0.429186405 0.804679199 0.544522233 0.918840742 1.545064759 FBgn0028171 l(3)S027344 lethal (3) S027344 http://flybase.org/reports/FBgn0028171 gene - - - "0273/44, l(3)S027344" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0261238 Alh Alhambra http://flybase.org/reports/FBgn0261238 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001965 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with HGNC:16063 inferred from sequence or structural similarity with HGNC:7138 inferred from mutant phenotype" "instar larval development ; GO:0002168 | inferred from mutant phenotype larval somatic muscle development ; GO:0007526 | inferred from expression pattern inferred from mutant phenotype male courtship behavior, veined wing generated song production ; GO:0045433 | inferred from mutant phenotype haltere development ; GO:0007482 | inferred from genetic interaction with Ubx regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype molting cycle, chitin-based cuticle ; GO:0007591 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:16063 inferred from sequence or structural similarity with HGNC:7138 inferred from direct assay "Alh, stk, Dalf, AF10, l(3)j8C8, l(3)j13A6, CG1070, anon-WO0118547.226, l(3j8C8, dAF10, l(3)j8c8, l(3)r13, l(3)g5, l(3)g2, l(3)84Be" "IPR001965:Zinc finger, PHD-type, IPR011011:Zinc finger, FYVE/PHD-type, IPR019786:Zinc finger, PHD-type, conserved site, IPR019787:Zinc finger, PHD-finger, IPR034732:Extended PHD (ePHD) domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG1070 27-Aug-18 DroID_v2018_08 "Drer\brd1a, Drer\jade3, Drer\brpf3b, Drer\mllt10, Drer\brpf3a, Drer\jade1" "Scer\NTO1, Scer\SNT2, Scer\HKR1" "Cele\zfp-1, Cele\phf-15, Cele\lin-49, Cele\phf-14" "Xtro\brpf3, Xtro\mllt6, Xtro\brd1, Xtro\mllt10, Xtro\jade3, Xtro\jade1" "Mmus\Brpf3, Mmus\Brd1, Mmus\Mllt10, Mmus\Brpf1, Mmus\Mllt6, Mmus\Jade1, Mmus\Jade3" "Hsap\MLLT6, Hsap\JADE3, Hsap\MLLT10, Hsap\BRPF1, Hsap\JADE1, Hsap\BRD1, Hsap\BRPF3" FBgn0045061 fs(1)127 female sterile (1) 127 http://flybase.org/reports/FBgn0045061 gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(1)127 - - 27-Aug-18 DroID_v2018_08 - - - - - - female sterile "oocyte,nurse cell & nucleus" FBgn0054015 CG34015 - http://flybase.org/reports/FBgn0054015 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR011146 molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BP1006, CG34015" IPR011146:HIT-like domain CG34015 27-Aug-18 DroID_v2018_08 "Drer\hint3, Drer\si:dkey-25e12.3" Scer\HNT1 Cele\hint-3 Xtro\hint3 Mmus\Hint3 Hsap\HINT3 FBgn0082168 p160S p160S http://flybase.org/reports/FBgn0082168 gene - - - "p160, p160S" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0025146 ms(3)A1 ms(3)A1 http://flybase.org/reports/FBgn0025146 - gene - - - ms(3)A1 - - 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,recessive" FBgn0031603 CG15432 - http://flybase.org/reports/FBgn0031603 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:24563 biological_process ; GO:0008150 | no biological data available nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000328467 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:24563 nucleoplasm ; GO:0005654 | inferred from sequence or structural similarity with HGNC:24563 "CG15432, cg15432" "IPR013865:Protein of unknown function DUF1754, eukaryotic" CG15432 27-Aug-18 DroID_v2018_08 Drer\fam32a - Cele\K01G5.8 Xtro\fam32a Mmus\Fam32a Hsap\FAM32A "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum DRSC00447 I -0.716213078 2.065140499 -0.397361645 1.424338214 0.637296688 0.106080053 FBgn0002224 l(3)68Ad lethal (3) 68Ad http://flybase.org/reports/FBgn0002224 FBgn0004711 gene - - - "l(3)68Ad', l(3)C117, D, l(3)D, l(3)68Ad" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0267457 asRNA:CR45807 - http://flybase.org/reports/FBgn0267457 non_protein_coding_gene - - - CR45807 - CR45807 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085581 CG41255 - http://flybase.org/reports/FBgn0085581 protein_coding_gene - - - CG41255 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002641 mal maroon-like http://flybase.org/reports/FBgn0002641 - protein_coding_gene molybdenum ion binding ; GO:0030151 | inferred from electronic annotation with InterPro:IPR005302 pyridoxal phosphate binding ; GO:0030170 | inferred from electronic annotation with InterPro:IPR005302 Mo-molybdopterin cofactor sulfurase activity ; GO:0008265 | inferred from sequence or structural similarity with UniProtKB:Q96EN8 Mo-molybdopterin cofactor sulfurase activity ; GO:0008265 | inferred from mutant phenotype Mo-molybdopterin cofactor biosynthetic process ; GO:0006777 | inferred from electronic annotation with InterPro:IPR028886 molybdopterin cofactor metabolic process ; GO:0043545 | inferred from sequence or structural similarity with UniProtKB:Q96EN8 molybdopterin cofactor metabolic process ; GO:0043545 | inferred from mutant phenotype ommochrome biosynthetic process ; GO:0006727 | inferred from mutant phenotype - "ma-l, bz, 5, CG1692, mal, SRF" "IPR000192:Aminotransferase class V domain, IPR005302:Molybdenum cofactor sulfurase, C-terminal, IPR005303:MOSC, N-terminal beta barrel, IPR011037:Pyruvate kinase-like, insert domain, IPR015421:Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015424:Pyridoxal phosphate-dependent transferase, IPR028886:Molybdenum cofactor sulfurase, IPR015422:Pyridoxal phosphate-dependent transferase, subdomain 2" CG1692 27-Aug-18 DroID_v2018_08 Drer\mocos Scer\BNA5 Cele\mocs-1 - Mmus\Mocos Hsap\MOCOS "viable,fertile,eye color defective,male fertile,male,male sterile,chemical sensitive,recessive" "pigment cell,Malpighian tubule" FBgn0037431 CG17917 - http://flybase.org/reports/FBgn0037431 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG17917 "IPR001858:Phosphatidylethanolamine-binding, conserved site, IPR008914:Phosphatidylethanolamine-binding protein" CG17917 27-Aug-18 DroID_v2018_08 "Drer\pebp1, Drer\mrpl38" "Scer\MRPL35, Scer\TFS1, Scer\YLR179C" "Cele\Y69E1A.5, Cele\F40A3.3" "Xtro\mrpl38, Xtro\pebp1, Xtro\pebp4" "Mmus\Pbp2, Mmus\Pebp4, Mmus\Mrpl38, Mmus\Pebp1" "Hsap\PEBP1, Hsap\MRPL38, Hsap\PEBP4" "viable,fertile" FBgn0035434 Drsl5 Drosomycin-like 5 http://flybase.org/reports/FBgn0035434 protein_coding_gene molecular_function ; GO:0003674 | no biological data available defense response to fungus ; GO:0050832 | inferred from direct assay defense response to fungus ; GO:0050832 | inferred from sequence or structural similarity with Drs extracellular region ; GO:0005576 | inferred from sequence or structural similarity with Drs inferred from sequence model "Dro5, CG10812, Dro-G, BcDNA:GH09576, Drs-lG, dro5, Drsl5, dmy5" "IPR003614:Knottin, scorpion toxin-like" CG10812 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0052039 CG32039 - http://flybase.org/reports/FBgn0052039 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BEST:GH02734, BcDNA:RE03722, CG32039" IPR031632:Small VCP/p97-interacting protein CG32039 27-Aug-18 DroID_v2018_08 Drer\si:ch73-147o17.1 - Cele\T28C6.7 - Mmus\Svip Hsap\SVIP viable FBgn0262552 Mod(GMroX1)149 - http://flybase.org/reports/FBgn0262552 gene - - - Mod(GMroX1)149 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266307 asRNA:CR44972 - http://flybase.org/reports/FBgn0266307 non_protein_coding_gene - - - CR44972 - CR44972 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035806 PGRP-SD Peptidoglycan recognition protein SD http://flybase.org/reports/FBgn0035806 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR006619 peptidoglycan binding ; GO:0042834 | inferred from direct assay peptidoglycan binding ; GO:0042834 | inferred from sequence or structural similarity with PGRP-SC1b N-acetylmuramoyl-L-alanine amidase activity ; GO:0008745 | NOT inferred from key residues innate immune response ; GO:0045087 | inferred from electronic annotation with InterPro:IPR017331 peptidoglycan catabolic process ; GO:0009253 | NOT inferred from key residues defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype innate immune response ; GO:0045087 | non-traceable author statement defense response to Gram-positive bacterium ; GO:0050830 | inferred from direct assay inferred from mutant phenotype defense response to Gram-positive bacterium ; GO:0050830 | inferred from mutant phenotype positive regulation of peptidoglycan recognition protein signaling pathway ; GO:0061059 | inferred from mutant phenotype inferred from genetic interaction with PGRP-LC detection of peptidoglycan ; GO:0032499 | inferred from mutant phenotype extracellular region ; GO:0005576 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay "CG7496, PGRP-SD, Dm PGRP-SD, pgrp-sd" "IPR002502:N-acetylmuramoyl-L-alanine amidase domain, IPR006619:Peptidoglycan recognition protein family domain, metazoa/bacteria, IPR015510:Peptidoglycan recognition protein, IPR017331:Peptidoglycan recognition protein, PGRP-S" CG7496 27-Aug-18 DroID_v2018_08 "Drer\pglyrp6, Drer\pglyrp5, Drer\pglyrp2" - - "Xtro\pglyrp1, Xtro\pglyrp2, Xtro\pglyrp1" "Mmus\Pglyrp3, Mmus\Pglyrp4, Mmus\Pglyrp2, Mmus\Pglyrp1" "Hsap\PGLYRP4, Hsap\PGLYRP2, Hsap\PGLYRP3, Hsap\PGLYRP1" "viable,fertile,immune response defective" FBgn0013492 l(1)90 lethal (1) 90 http://flybase.org/reports/FBgn0013492 - gene - - - "l90, l(1)90" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0267719 lncRNA:CR46052 - http://flybase.org/reports/FBgn0267719 non_protein_coding_gene - - - CR46052 - CR46052 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267028 lncRNA:CR45472 - http://flybase.org/reports/FBgn0267028 non_protein_coding_gene - - - "CR45472, CR43790, CR43CR43790786, CR43791" - CR45472 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0029728 CG2861 - http://flybase.org/reports/FBgn0029728 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG2861 - CG2861 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0259382 EP-329 - http://flybase.org/reports/FBgn0259382 gene - - - EP-329 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing,wing vein" FBgn0083995 CG41353 - http://flybase.org/reports/FBgn0083995 protein_coding_gene - - - CG41353 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000109 Aprt Adenine phosphoribosyltransferase http://flybase.org/reports/FBgn0000109 "FBgn0035288, FBgn0063099" protein_coding_gene adenine phosphoribosyltransferase activity ; GO:0003999 | inferred from electronic annotation with InterPro:IPR005764 adenine salvage ; GO:0006168 | inferred from electronic annotation with InterPro:IPR005764 nucleoside metabolic process ; GO:0009116 | inferred from electronic annotation with InterPro:IPR000836 cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR005764 "aprt, CG18315, BcDNA:LP07986, Aprt" "IPR000836:Phosphoribosyltransferase domain, IPR005764:Adenine phosphoribosyl transferase, IPR029057:Phosphoribosyltransferase-like" CG18315 27-Aug-18 DroID_v2018_08 "Drer\zgc:174895, Drer\aprt" "Scer\APT2, Scer\APT1" Cele\T19B4.3 "Xtro\aprt, Xtro\LOC100145149" Mmus\Aprt Hsap\APRT "chemical resistant,long lived,electrophoretic variant,fast,slow,viable" FBgn0032772 CG17350 - http://flybase.org/reports/FBgn0032772 protein_coding_gene - - - CG17350 - CG17350 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" FBgn0030305 Uba5 Ubiquitin activating enzyme 5 http://flybase.org/reports/FBgn0030305 protein_coding_gene UFM1 activating enzyme activity ; GO:0071566 | inferred from sequence or structural similarity with HGNC:23230 protein ufmylation ; GO:0071569 | inferred from sequence or structural similarity with HGNC:23230 locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype synapse organization ; GO:0050808 | inferred from mutant phenotype molybdopterin synthase complex ; GO:0019008 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:23230 "CG1749, dMoaD, MoeB, Uba5, dUBA5" "IPR000594:THIF-type NAD/FAD binding fold, IPR029752:D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1" CG1749 27-Aug-18 DroID_v2018_08 Drer\uba5 Scer\UBA4 Cele\uba-5 Xtro\uba5 Mmus\Uba5 Hsap\UBA5 "lethal,some die during pupal stage,viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0259317 C17 - http://flybase.org/reports/FBgn0259317 gene - - - C17 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible wing vein FBgn0024900 anon-a5 anon-a5 http://flybase.org/reports/FBgn0024900 - repeat_region - - - "a5, anon-a5" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001715 l(1)ESHS36 lethal (1) ESHS36 http://flybase.org/reports/FBgn0001715 - gene - - - l(1)ESHS36 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0016126 CaMKI Calcium/calmodulin-dependent protein kinase I http://flybase.org/reports/FBgn0016126 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 calmodulin-dependent protein kinase activity ; GO:0004683 | inferred from biological aspect of ancestor with PANTHER:PTN001218105 calmodulin-dependent protein kinase activity ; GO:0004683 | inferred from sequence or structural similarity calmodulin binding ; GO:0005516 | traceable author statement protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement" peptidyl-threonine phosphorylation ; GO:0018107 | inferred from biological aspect of ancestor with PANTHER:PTN000680267 intracellular signal transduction ; GO:0035556 | inferred from biological aspect of ancestor with PANTHER:PTN000680267 protein phosphorylation ; GO:0006468 | non-traceable author statement protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity peptidyl-serine phosphorylation ; GO:0018105 | inferred from biological aspect of ancestor with PANTHER:PTN000680267 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from sequence or structural similarity intracellular ; GO:0005622 | inferred from biological aspect of ancestor with PANTHER:PTN000680267 "caMKI, Calcium/calmodulin-dependent protein kinase, CamKI, CG1495, camKI, dCKI, CaMKI, CaMK1, CamK1" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR020636:Calcium/calmodulin-dependent/calcium-dependent protein kinase" CG1495 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-27e6.1, Drer\spegb, Drer\stk33, Drer\camk2b, Drer\mylk4b, Drer\stk17b, Drer\camkvb, Drer\dapk2a, Drer\si:dkey-240h12.4, Drer\camk1ga, Drer\dapk2b, Drer\capslb, Drer\camk1a, Drer\uhmk1, Drer\triob, Drer\camk2a, Drer\pskh1, Drer\camk1db, Drer\mylk4a, Drer\camk2d1, Drer\camk1gb, Drer\trioa, Drer\ttnb, Drer\camk1b, Drer\camk1da, Drer\camkvl, Drer\camk4, Drer\camk2g2, Drer\camkva, Drer\zgc:153952, Drer\capsla, Drer\camk2g1, Drer\stk17a, Drer\camk2d2, Drer\pnck, Drer\si:ch73-60h1.1, Drer\dapk3, Drer\dapk1, Drer\camk2b1, Drer\mylk3" "Scer\IKS1, Scer\DUN1, Scer\CMK1, Scer\CMK2, Scer\TDA1, Scer\RCK1, Scer\RCK2, Scer\MEK1, Scer\PRR1" "Cele\R06A10.4, Cele\cmk-1" "Xtro\pskh1, Xtro\capsl, Xtro\pnck, Xtro\camk1, Xtro\caps, Xtro\kalrn, Xtro\camk4, Xtro\camkv, Xtro\stk33, Xtro\dapk3, Xtro\camk1d, Xtro\trio, Xtro\mylk4, Xtro\dapk2, Xtro\camk1g, Xtro\mylk3, Xtro\dapk1, Xtro\pskh2, Xtro\stk17a, Xtro\dclk2" "Mmus\Camk1d, Mmus\Mylk3, Mmus\Dclk2, Mmus\Obscn, Mmus\Stk33, Mmus\Mylk4, Mmus\Pnck, Mmus\Trio, Mmus\Dapk1, Mmus\Speg, Mmus\Dapk2, Mmus\Stk17b, Mmus\Camk1g, Mmus\Mylk2, Mmus\Dclk1, Mmus\Camkv, Mmus\Dapk3, Mmus\Camk2g, Mmus\Camk2a, Mmus\Capsl, Mmus\Camk1, Mmus\Caps2, Mmus\Pskh1, Mmus\Camk2b, Mmus\Camk4, Mmus\Uhmk1" "Hsap\PNCK, Hsap\MYLK4, Hsap\DAPK1, Hsap\CAPSL, Hsap\DAPK2, Hsap\CAMK4, Hsap\CAPS, Hsap\STK17B, Hsap\CAMK2A, Hsap\CAMK1D, Hsap\PSKH2, Hsap\DCLK1, Hsap\CAMK1, Hsap\UHMK1, Hsap\OBSCN, Hsap\TRIO, Hsap\STK17A, Hsap\CAPS2, Hsap\CAMK2D, Hsap\CAMK2G, Hsap\CAMK1G, Hsap\DAPK3, Hsap\CAMK2B, Hsap\MYLK2, Hsap\SPEG, Hsap\MYLK3, Hsap\PSKH1, Hsap\STK33, Hsap\CAMKV" " adult stage , pupal stage&&larval stage&&adult stage " eye

"viable,fertile" FBgn0084036 CG41476 - http://flybase.org/reports/FBgn0084036 protein_coding_gene - - - CG41476 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260623 2L3328 - http://flybase.org/reports/FBgn0260623 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L3328 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0261526 NT1 Neurotrophin 1 http://flybase.org/reports/FBgn0261526 protein_coding_gene growth factor activity ; GO:0008083 | inferred from mutant phenotype Toll binding ; GO:0005121 | inferred from sequence or structural similarity with spz motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype regulation of cell death ; GO:0010941 | inferred from direct assay Toll signaling pathway ; GO:0008063 | inferred from sequence or structural similarity with spz central nervous system formation ; GO:0021556 | inferred from mutant phenotype regulation of neuronal synaptic plasticity in response to neurotrophin ; GO:0031637 | inferred from mutant phenotype nervous system development ; GO:0007399 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype extracellular region ; GO:0005576 | inferred from sequence or structural similarity with spz "NT1, dNT1, Spz2, CG18318, DNT1, CT30097, spz2, CG42576, CG32242, CG32244, Spz-2" "IPR029034:Cystine-knot cytokine, IPR032104:Spaetzle" CG42576 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0028620 l(2)10565a lethal (2) 10565a http://flybase.org/reports/FBgn0028620 gene - - - "l(2)10565, l(2)10565a" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0262516 Trpml "Transient receptor potential cation channel, mucolipin" http://flybase.org/reports/FBgn0262516 protein_coding_gene "calcium channel activity ; GO:0005262 | inferred from sequence or structural similarity cation channel activity ; GO:0005261 | inferred from sequence or structural similarity with pyx cation channel activity ; GO:0005261 | inferred from direct assay intracellular ligand-gated ion channel activity ; GO:0005217 | inferred from direct assay phosphatidylinositol-3,5-bisphosphate binding ; GO:0080025 | inferred from direct assay" lateral inhibition ; GO:0046331 | inferred from mutant phenotype autophagosome maturation ; GO:0097352 | inferred from mutant phenotype negative regulation of growth of symbiont in host ; GO:0044130 | inferred from mutant phenotype calcium ion transport ; GO:0006816 | inferred from sequence or structural similarity cellular calcium ion homeostasis ; GO:0006874 | inferred from mutant phenotype autophagy ; GO:0006914 | inferred from mutant phenotype positive regulation of TOR signaling ; GO:0032008 | inferred from mutant phenotype cation transport ; GO:0006812 | inferred from sequence or structural similarity with pyx positive regulation of synaptic growth at neuromuscular junction ; GO:0045887 | inferred from mutant phenotype cation transport ; GO:0006812 | inferred from direct assay lysosome ; GO:0005764 | inferred from direct assay late endosome membrane ; GO:0031902 | inferred from direct assay lysosomal membrane ; GO:0005765 | inferred from direct assay cation channel complex ; GO:0034703 | inferred from sequence or structural similarity with pyx late endosome ; GO:0005770 | inferred from direct assay endolysosome membrane ; GO:0036020 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "trpml, CT25240, CG8743, l(3)76BDi, DmTRPML, TRPML, Trpml" "IPR013122:Polycystin cation channel, PKD1/PKD2" CG8743 27-Aug-18 DroID_v2018_08 "Drer\mcoln1a, Drer\mcoln3b, Drer\mcoln3a, Drer\mcoln2, Drer\mcoln1b" - Cele\cup-5 "Xtro\mcoln2, Xtro\LOC101734792, Xtro\mcoln3, Xtro\mcoln1" "Mmus\Mcoln3, Mmus\Mcoln2, Mmus\Mcoln1" "Hsap\MCOLN1, Hsap\MCOLN2, Hsap\MCOLN3" DRSC11032 I -1.633237991 -0.323258828 0.189626555 -0.17759202 0.022775855 -0.333471541 FBgn0044345 scratch-like2 scratch-like2 http://flybase.org/reports/FBgn0044345 gene - - - scratch-like2 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051528 CG31528 - http://flybase.org/reports/FBgn0051528 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BEST:GH26112, BcDNA:GH26112, CG31528" "IPR000626:Ubiquitin domain, IPR015940:Ubiquitin-associated domain, IPR015496:Ubiquilin, IPR029071:Ubiquitin-related domain, IPR009060:UBA-like" CG31528 27-Aug-18 DroID_v2018_08 Drer\ubqln4 Scer\DSK2 "Cele\F49C12.9, Cele\ubql-1" "Xtro\ubqln1, Xtro\ubqln4" "Mmus\4931431F19Rik, Mmus\Ubqln2, Mmus\Ubqln1, Mmus\Ubqlnl, Mmus\Ubqln4, Mmus\Ubqln3" "Hsap\UBQLN1, Hsap\UBQLN4, Hsap\UBQLN2, Hsap\UBQLN3, Hsap\UBQLNL" viable FBgn0000490 dpp decapentaplegic http://flybase.org/reports/FBgn0000490 FBgn0010065 protein_coding_gene "growth factor activity ; GO:0008083 | inferred from electronic annotation with InterPro:IPR001111, InterPro:IPR001839, InterPro:IPR017948 transforming growth factor beta receptor binding ; GO:0005160 | non-traceable author statement morphogen activity ; GO:0016015 | non-traceable author statement collagen binding ; GO:0005518 | inferred from direct assay transforming growth factor beta receptor binding ; GO:0005160 | inferred from biological aspect of ancestor with PANTHER:PTN000218063 cytokine activity ; GO:0005125 | inferred from biological aspect of ancestor with PANTHER:PTN000218063 protein homodimerization activity ; GO:0042803 | inferred from physical interaction with UniProtKB:P07713 heparin binding ; GO:0008201 | inferred from direct assay morphogen activity ; GO:0016015 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with dally protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with UniProtKB:P54631" "anterior Malpighian tubule=0061327; hindgut morphogenesis=0007442; cell shape=0008360; apoptotic process=0042981;germ cell=0007281; genital disc=0035215; female germ-line stem cell population maintenance=0036099; cardioblast differentiation=0010002; negative .. salivary gland boundary specification=0045705; cell fate specification=0001708; amnioserosa formation=0007378; wing disc pattern formation=0035222; zygotic specification of dorsal/ventral axis=0007352; imaginal disc pattern formation=0007447; negative .. gene expression=0010629 | inferred from expression pattern open tracheal system=0007424; spectrosome organization=0030721; wing disc pattern formation=0035222; with UniProtKB:P27091 heart=0007507; imaginal disc=0007444; dorsal closure=000739; hindgut morphogenesis=0048619; wing disc proximal/distal pattern formation=0007473; genital disc sexually dimorphic=0035263; imaginal disc pattern formation=0007447; germ-line stem cell division=0042078; progression of morphogenetic furrow involved in compound eye morphogenesis=0007458; labial disc=0035217; branched duct epithelial cell fate determination, open tracheal system=0046845; heart=0007507; BMP signaling pathway involved in Malpighian tubule cell chemotaxis=0061353; genital disc anterior/posterior pattern formation=0035224 | inferred from expression pattern dorsal/ventral axis specification=0009950; ovarian follicle cell=0030707; dorsal closure=0007391; imaginal disc-derived wing vein morphogenesis=0008586; chorion-containing eggshell formation=0007304; hemocyte=0007516; anterior/posterior pattern specification, imaginal disc=0007448; zygotic specification of dorsal/ventral axis=0007352; leg disc proximal/distal pattern formation=0007479; SMAD protein signal transduction=0060395; cell differentiation=0045595; mesoderm=0007498; dorsal appendage formation=0046843; eye-antennal disc morphogenesis=0007455; larval lymph gland hemocyte differentiation=0035168; dorsal closure=0007391 | with bsk cell fate determination=0001709; stem cell population maintenance=0019827; BMP signaling pathway=0030509; nurse cell apoptotic process=0045476; compound eye morphogenesis=0001745; imaginal disc-derived wing vein specification=0007474; cell fate specification=0001708; dorsal closure, leading edge cell fate determination=0007393; epithelial cell migration, open tracheal system=0007427; imaginal disc-derived wing vein specification=0007474; hindgut morphogenesis=0007442; maternal specification of dorsal/ventral axis, oocyte, soma encoded=0007313; open tracheal system=0007424; Malpighian tubule morphogenesis=0007443; pathway-restricted SMAD protein phosphorylation=0010862; germ-line stem cell population maintenance=0030718; imaginal disc growth=0007446; foregut morphogenesis=0007440;organ growth=0046620; germ cell migration=0008354; leg disc proximal/distal pattern formation=0007479; mesoderm=0007498; cell proliferation=0042127; imaginal disc-derived wing morphogenesis=0007476; ectoderm=0007398; germ-line stem cell division=0042078; fusion cell fate specification=0035156; male germ-line stem cell population maintenance=0036098; transforming growth factor beta receptor signaling pathway=0007179; muscle organ=0048636; .. MAPK cascade=0043408; cell proliferation=0008285; pericardial nephrocyte differentiation=0061320; lymph gland=0048542; gene expression=0010629; dorsal/ventral axis specification=0009950; amnioserosa formation=0007378; tube diameter, open tracheal system=0035158; BMP signaling pathway=0030509; anterior/posterior axis specification=0009948" cytoneme ; GO:0035230 | colocalizes_with inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay intracellular ; GO:0005622 | inferred from direct assay endosome ; GO:0005768 | colocalizes_with inferred from direct assay "dpp, Dpp, BMP, DPP, TGF-beta, TGFbeta, Dm-DPP, TGF-b, CG9885, l(2)k17036, l(2)10638, l(2)22Fa, shv, M(2)LS1, ho, blk, Tg, M(2)23AB, Hin-d, DPP-C, TGF-betagr;/SMAD" "IPR001111:TGF-beta, propeptide, IPR001839:Transforming growth factor-beta, C-terminal, IPR015615:Transforming growth factor-beta-related, IPR017948:Transforming growth factor beta, conserved site, IPR029034:Cystine-knot cytokine" CG9885 27-Aug-18 DroID_v2018_08 "Drer\gdf11, Drer\gdf2, Drer\gdf6a, Drer\gdf9, Drer\bmp6, Drer\amh, Drer\mstna, Drer\bmp8a, Drer\ndr2, Drer\inhbab, Drer\bmp16, Drer\bmp2b, Drer\lft1, Drer\inhbb, Drer\bmp2a, Drer\gdf10a, Drer\tgfb2l, Drer\bmp7b, Drer\bmp3, Drer\gdf7, Drer\bmp15, Drer\lft2, Drer\tgfb3, Drer\inha, Drer\bmp10, Drer\spaw, Drer\mstnb, Drer\bmp4, Drer\tgfb1b, Drer\gdf6b, Drer\gdf5, Drer\bmp7a, Drer\gdf3, Drer\bmp10l, Drer\tgfb1a, Drer\ndr1, Drer\admp, Drer\gdf10b, Drer\inhbaa, Drer\tgfb2, Drer\LOC100329520" - "Cele\daf-7, Cele\dbl-1, Cele\unc-129, Cele\tig-2" "Xtro\bmp6, Xtro\gdf11.1, Xtro\bmp15, Xtro\nodal5, Xtro\admp, Xtro\gdf7, Xtro\bmp8, Xtro\lefty, Xtro\bmp2, Xtro\nodal, Xtro\nodal, Xtro\bmp3, Xtro\bmp7.2, Xtro\gdf5, Xtro\bmp10, Xtro\nodal1, Xtro\gdf3, Xtro\nodal6, Xtro\inhbc.1, Xtro\bmp5, Xtro\mstn.1, Xtro\tgfb1, Xtro\gdf10, Xtro\gdf1, Xtro\inha, Xtro\tgfb2, Xtro\bmp7.1, Xtro\bmp4, Xtro\gdf2, Xtro\gdf9" "Mmus\Mstn, Mmus\Gdf7, Mmus\Bmp8b, Mmus\Inhbe, Mmus\Gdf9, Mmus\Inhbc, Mmus\Bmp4, Mmus\Gdf15, Mmus\Bmp6, Mmus\Lefty2, Mmus\Bmp2, Mmus\Lefty1, Mmus\Gdf3, Mmus\Gdf6, Mmus\Bmp5, Mmus\Inha, Mmus\Gdf2, Mmus\Amh, Mmus\Tgfb2, Mmus\Inhbb, Mmus\Gdf11, Mmus\Nodal, Mmus\Tgfb1, Mmus\Bmp10, Mmus\Bmp15, Mmus\Gdf1, Mmus\Bmp3, Mmus\Bmp7, Mmus\Tgfb3, Mmus\Gdf5, Mmus\Gdf10, Mmus\Inhba, Mmus\Bmp8a" "Hsap\INHA, Hsap\BMP2, Hsap\GDF9, Hsap\INHBC, Hsap\GDF1, Hsap\LEFTY2, Hsap\MSTN, Hsap\BMP8A, Hsap\GDF5, Hsap\AMH, Hsap\LEFTY1, Hsap\GDF7, Hsap\NODAL, Hsap\BMP3, Hsap\GDF11, Hsap\BMP4, Hsap\BMP5, Hsap\GDF15, Hsap\GDF2, Hsap\TGFB3, Hsap\BMP10, Hsap\TGFB1, Hsap\BMP6, Hsap\BMP15, Hsap\GDF6, Hsap\BMP8B, Hsap\INHBA, Hsap\GDF10, Hsap\BMP7, Hsap\INHBE, Hsap\TGFB2, Hsap\GDF3, Hsap\INHBB" " larval stage | third instar , embryonic stage | cellular blastoderm , embryonic stage | stage 14 , embryonic stage | stage 13 , embryonic stage , embryonic stage | mid-late , prepupal stage , embryonic stage | stage 11-17 , larval stage | first instar , pupal stage | >=18-20 hr , embryonic stage | stage 11 , prepupal stage | 6-9 hr , embryonic stage | mid &late , embryonic stage | stage 12 , embryonic stage | stage 13-16 , larval stage " " ventral thoracic disc | restricted

, dorsal ectoderm anlage

, dorsal mesothoracic disc | restricted

, male genital disc | restricted

, embryonic/larval esophagus

, embryonic brain

, visceral mesoderm &&of parasegment 8--12

, ventral mesothoracic disc | resticted

, parasegment 7

{ + abd-AM1 } , midgut constriction 3

, female genital disc | restricted

, midgut constriction 2

, imaginal disc primordium

, wing vein | primordium

, eye-antennal disc | restricted

, midgut

{ v dpps21/dpps4 } , parasegment 7 visceral mesoderm

{ - Ubx1 } , thoracic segment

, dorsal mesothoracic disc | restriced

, procephalic segment

, foregut

{ + abd-AM1 } , larval labral segment sense organ

, visceral mesoderm &&of parasegment 7

, larval brain | restricted

, gastric caecum

, dorsal mesothoracic disc | anterior/posterior compartment boundary

, embryonic/larval hindgut

, embryonic/larval foregut

{ - dpps21/dpps4 } , visceral mesoderm &&of parasegment 7--12

, embryonic/larval pharynx

" " embryonic stage | stage 14-17 , larval stage | third instar , embryonic stage | mid-late , embryonic stage | stage 16-17 , embryonic stage | stage 12 " " midgut constriction 2

, morphogenetic furrow

, parasegment 3,8..12 visceral mesoderm

{ + Ubxhs.PU, Ubx-, abd-A- } , parasegment 7 &&of endoderm

, visceral mesoderm &&of parasegment 2--12

, parasegment 7 &&of visceral mesoderm

, visceral mesoderm &&of parasegment 7

, eye disc | ubiquitous

, parasegment 6..7 visceral mesoderm

{ + Ubxhs.PU } , dorsal mesothoracic disc | ubiquitous

, parasegment 3,6..7 visceral mesoderm

{ - Ubx6.28 } , parasegment 3..7 visceral mesoderm

{ + abd-AMX1 } , parasegment 3,6..12 visceral mesoderm

{ $ Ubx-, abd-A- } , ventral thoracic disc | ubiquitous

, dorsal mesothoracic disc | anterior posterior gradient

" "visible,recessive,lethal,some die during embryonic stage,dominant,short lived,RU486 conditional,circadian rhythm defective,heat sensitive,viable,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of embryonic stage,wild-type,increased cell death,somatic clone,partially lethal - majority die,size defective,reduced,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of P-stage,some die during pharate adult stage,female fertile,increased cell number,immune response defective,conditional,homeotic,tumorigenic,female sterile,hyperplasia,decreased cell number" ",embryonic/first instar larval cuticle,wing vein,wing,unguis,leg,eye,antenna,medulla neuropil,ommatidium,embryonic dorsal epidermis,cephalopharyngeal skeleton,filzkorper,embryonic thorax,embryonic head,head,antennal disc,ventral thoracic disc,spermatogonium,ventral nerve cord commissure,longitudinal connective,frons,retina,morphogenetic furrow,eye-antennal disc,male genitalia,penis,gonopod thorn bristle,gonopod long bristle,dorsal appendage,mesothoracic extracoxal depressor muscle 66,submarginal cell,1st posterior cell,cephalic furrow,amnioserosa,vibrissae,maxillary palpus,rostral membrane,gena,adult head,sternite,clasper,female gonopod,follicle cell,tergite,embryonic epidermis,dil cell,crossvein,wing cell,anterior crossvein,dpphr4,germarium,female germline stem cell,embryonic abdomen,abdominal segment,chorion,egg operculum,egg,micropyle,embryonic head epidermis,embryonic optic lobe primordium,wing disc,cardial valve,alula,female analia,male terminalia,capitellum,tibia,femur,sex comb,arista,fourth segment of antenna,fifth segment of antenna,taste bristle,genital disc,imaginal disc,egg chamber,macrochaeta,microchaeta,scutum,anal plate,lateral plate,head capsule,haltere,crystal cell,posterior crossvein,embryonic gnathal segment,cardiogenic mesoderm,embryonic/larval lymph gland,cardioblast,embryonic optic lobe,mitotic domain 1,mitotic domain 3,mitotic domain 5,embryonic hindgut,embryonic large intestine,extended germ band embryo,cuticle,Bolwig organ,corpus cardiacum primordium,embryo,larval head,gastric caecum,embryonic/larval midgut,scutellar bristle,third segment of antenna,dorsal hair,tegula,supraalar bristle,secondary pigment cell,tertiary pigment cell,interommatidial bristle,wing margin bristle,embryonic anal pad,maxillary palp sense organ,antennal sense organ,gastric caecum primordium,midgut constriction,embryonic dorsal pouch primordium,male analia,pseudotrachea,dpphr56,germline cell,hub cell,genital disc primordium,labellum,scutellum,embryonic/larval cuticle,embryonic/larval foregut,embryonic/larval pericardial cell,mesoderm,embryonic/larval heart,hemocyte,plasmatocyte,lamellocyte,A1-7 dorsal oblique muscle 1,haltere disc,sensillum campaniformium of dorsal radius,sensillum campaniformium of proximal ventral radius,prescutum,vulva,dorsal double row,ventral double row,dorsal triple row,medial triple row,ventral triple row,terminalia,tracheocyte,embryonic/larval dorsal trunk,embryonic/larval lateral trunk,eye disc,wing hair,germarium cap cell,stem cell fusome,male germline stem cell,primary spermatocyte,tracheal branch primordium,embryonic/larval tracheal system,germline cyst,oocyte,interfollicle cell,presumptive embryonic/larval tracheal system,embryonic/larval dorsal branch,embryonic anterior Malpighian tubule,zen.Kr.PF,twi.PGa,fat body/gonad primordium,epidermis,spermatocyte,primary gonial cell,spermatid,testis,wing disc |,embryonic/larval visceral branch,tracheal tip cell |,btl.PS,spiracular chamber,midgut,GMR.PF,subretinal glial cell,dorsal mesothoracic disc primordium,prothoracic leg,mesothoracic leg,metathoracic leg,dpp.blk1,visual primordium,labral segment,ovary,female germline cell,adult midgut precursor cell" DRSC00118 I 0.328255955 2.378687749 -0.31386119 0.123479339 -0.259937839 -0.103012015 FBgn0020182 Ddc::ftz Ddc::ftz http://flybase.org/reports/FBgn0020182 - engineered_fusion_gene - - - Ddc::ftz - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0019639 ApI Apurinic/apyrimidinic endonuclease I http://flybase.org/reports/FBgn0019639 - gene DNA-(apurinic or apyrimidinic site) lyase activity ; GO:0003906 | inferred from direct assay DNA repair ; GO:0006281 | inferred from direct assay - ApI - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0069069 20-51 20-51 http://flybase.org/reports/FBgn0069069 gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available 20-51 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,female sterile,germline clone" FBgn0266500 s-200 - http://flybase.org/reports/FBgn0266500 gene - - - s-200 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040026 CG17653 - http://flybase.org/reports/FBgn0040026 protein_coding_gene - - - CG17653 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000625 eyg eyegone http://flybase.org/reports/FBgn0000625 FBgn0011647 protein_coding_gene "RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | non-traceable author statement" compound eye development ; GO:0048749 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from direct assay eye-antennal disc development ; GO:0035214 | inferred from mutant phenotype eye development ; GO:0001654 | inferred from mutant phenotype salivary gland morphogenesis ; GO:0007435 | traceable author statement antennal development ; GO:0007469 | inferred from mutant phenotype notum development ; GO:0007477 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "lun, Bk27, BK27, CG10488, eyg, Eyg, EYG" "IPR017970:Homeobox, conserved site, IPR001356:Homeobox domain, IPR001523:Paired domain, IPR009057:Homeobox domain-like, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR011990:Tetratricopeptide-like helical domain" CG10488 27-Aug-18 DroID_v2018_08 "Drer\pax3a, Drer\mxtx2, Drer\mxtx1, Drer\pax3b, Drer\mixl1, Drer\pax6b, Drer\pax4, Drer\pax7b" - Cele\eyg-1 "Xtro\bix1.1, Xtro\sia1, Xtro\mixer, Xtro\pax7, Xtro\pax6, Xtro\mix1, Xtro\pax3" "Mmus\Pax3, Mmus\Pax4, Mmus\Mixl1, Mmus\Cphx1, Mmus\Duxbl1, Mmus\Duxbl2, Mmus\Pax7, Mmus\Duxbl3, Mmus\Pax6, Mmus\Cphx3" "Hsap\PAX3, Hsap\DUX4, Hsap\PAX6, Hsap\PAX7, Hsap\DUXA, Hsap\MIXL1, Hsap\PAX4" " embryonic stage , larval stage | third instar , embryonic stage | stage >=11 , larval stage | second instar-- L | third instar " " adult eye primordium

, ventral thoracic disc | restricted

, dorsal mesothoracic disc | restricted

, salivary gland body primordium

, eye disc

, embryonic head | restricted

, eye disc | dorsal && morphogenetic furrow | anterior to

, eye disc | anterior

, antennal disc | central

, embryonic/larval posterior spiracle | vicinity of

, epidermis | segmentally repeated

" larval stage | third instar dorsal mesothoracic disc | restricted

"lethal,recessive,cell growth defective,somatic clone,lethal - all die before end of pupal stage,visible,some die during pupal stage,viable,fertile,lethal - all die before end of P-stage,some die during pharate adult stage,semidominant,partially lethal - majority die,increased cell death,planar polarity defective,hyperplasia" "thorax,eye disc,eye-antennal disc,head,cell non-autonomous,somatic clone,eye,retina,adult head,adult thorax,dorsocentral bristle,mesothoracic tergum,microchaeta,embryonic/larval salivary gland duct,salivary gland imaginal ring,photoreceptor cell,ectopic,ventral,eye | pharate adult stage,thorax | pharate adult stage,supernumerary,wing disc,head | pharate adult stage,scutum,scutellum,macrochaeta,macrochaeta & scutumMS248,macrochaeta & scutum455.2,macrochaeta & scutumush-MD751,macrochaeta & scutumpnr-MD237,macrochaeta & scutumMD-638,wing,adult cuticle,proximal,heat sensitive,trichogen cell" FBgn0037251 CG9804 - http://flybase.org/reports/FBgn0037251 protein_coding_gene "octanoyltransferase activity ; GO:0016415 | inferred from electronic annotation with InterPro:IPR000544, InterPro:IPR020605 lipoyl(octanoyl) transferase activity ; GO:0033819 | inferred from sequence or structural similarity with UniProtKB:Q9SXP7" "lipoate biosynthetic process ; GO:0009107 | inferred from electronic annotation with InterPro:IPR000544, InterPro:IPR020605 protein lipoylation ; GO:0009249 | inferred from sequence or structural similarity with UniProtKB:Q9SXP7" "cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR000544, InterPro:IPR020605" CG9804 "IPR000544:Octanoyltransferase, IPR004143:Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain, IPR020605:Octanoyltransferase, conserved site" CG9804 27-Aug-18 DroID_v2018_08 Drer\lipt2 Scer\LIP2 Cele\lpl-1 Xtro\lipt2 Mmus\Lipt2 Hsap\LIPT2 viable FBgn0066122 E(sda)M E(sda)M http://flybase.org/reports/FBgn0066122 gene - - - "E(sda)M, Line M" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065531 l(2)SH1108 lethal (2) SH1108 http://flybase.org/reports/FBgn0065531 gene - - - "l(2)SH1108, l(2)SH2 1108" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0045054 fs(1)217 female sterile (1) 217 http://flybase.org/reports/FBgn0045054 gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(1)217 - - 27-Aug-18 DroID_v2018_08 - - - - - - female sterile "egg chamber,follicle cell" FBgn0037899 RpL24-like Ribosomal protein L24-like http://flybase.org/reports/FBgn0037899 protein_coding_gene structural constituent of ribosome ; GO:0003735 | traceable author statement positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype assembly of large subunit precursor of preribosome ; GO:1902626 | inferred from biological aspect of ancestor with PANTHER:PTN000846433 ribosomal large subunit assembly ; GO:0000027 | inferred from biological aspect of ancestor with PANTHER:PTN000846433 cytoplasmic translation ; GO:0002181 | traceable author statement cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement "RpL24-like, CG6764" "IPR000988:Ribosomal protein L24e-related, IPR011017:TRASH domain, IPR023442:Ribosomal protein L24e, conserved site" CG6764 27-Aug-18 DroID_v2018_08 Drer\rsl24d1 Scer\RLP24 Cele\rpl-24.2 Xtro\rsl24d1 Mmus\Rsl24d1 Hsap\RSL24D1 FBgn0260661 U5-40k - http://flybase.org/reports/FBgn0260661 protein_coding_gene - - - U5-40k - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266844 lncRNA:CR45306 - http://flybase.org/reports/FBgn0266844 non_protein_coding_gene - - - CR45306 - CR45306 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065393 l(2)SH1625 lethal (2) SH1625 http://flybase.org/reports/FBgn0065393 gene - - - "l(2)SH1625, l(2)SH2 1625" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0044472 EP1592 EP1592 http://flybase.org/reports/FBgn0044472 gene - - - EP1592 - - 27-Aug-18 DroID_v2018_08 - - - - - - neuroanatomy defective "intersegmental nerve,anterior fascicle & synapse,anterior fascicle & synapse | supernumerary" FBgn0013999 Op29 Ovary protein-29kD http://flybase.org/reports/FBgn0013999 - gene - - gap junction ; GO:0005921 | inferred from direct assay "Dop29, Op29" - - 27-Aug-18 DroID_v2018_08 - - - - - - oogenesis stage && adult stage | female ovary

FBgn0082375 EP1457 EP1457 http://flybase.org/reports/FBgn0082375 gene - - - EP1457 - - 27-Aug-18 DroID_v2018_08 - - - - - - "germline cell,male" FBgn0264420 FCO-E - http://flybase.org/reports/FBgn0264420 gene - - - FCO-E - - 27-Aug-18 DroID_v2018_08 - - - - - - "increased cell death,somatic clone" "follicle cell,somatic clone" FBgn0035420 CG14967 - http://flybase.org/reports/FBgn0035420 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14967 "IPR019443:FMP27, C-terminal, IPR019441:FMP27, GFWDK domain, IPR019439:FMP27, N-terminal, IPR019409:FMP27, domain of unknown function DUF2405" CG14967 27-Aug-18 DroID_v2018_08 - "Scer\FMP27, Scer\YPR117W" Cele\F31C3.3 Xtro\kiaa0100 Mmus\2610507B11Rik Hsap\KIAA0100 viable FBgn0053738 snmRNA:430l snmRNA:430:CR33738 http://flybase.org/reports/FBgn0053738 non_protein_coding_gene - - - "CR33738, snmRNA:430:CR33738" - CR33738 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0052272 tRNA:Lys-CTT-1-13 transfer RNA:Lysine-CTT 1-13 http://flybase.org/reports/FBgn0052272 tRNA_gene AAG codon-amino acid adaptor activity ; GO:0033444 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033444 cytosol ; GO:0005829 | inferred by curator from GO:0033444 "CR32272, AE002584.trna20-LysCTT, tRNA[Lys][[2]], tRNA:lys2:63B, tRNA:K2:63B, tRNA:K2, tRNA:K:CTT:AE002584-b, chr3L.trna48-LysCTT, tRNA-Lys-CTT-1-13, tRNA:Lys-CTT-1-13, tRNA:CR32272, AAG" - CR32272 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263834 CR43696 - http://flybase.org/reports/FBgn0263834 pseudogene_attribute - - - CR43696 - CR43696 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060841 l(3)S049413b lethal (3) S049413b http://flybase.org/reports/FBgn0060841 gene - - - "0494/13, l(3)S049413b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0036850 Gem2 Gemin2 http://flybase.org/reports/FBgn0036850 protein_coding_gene molecular_function ; GO:0003674 | no biological data available spliceosomal complex assembly ; GO:0000245 | inferred from electronic annotation with InterPro:IPR017364 adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype spliceosomal snRNP assembly ; GO:0000387 | inferred from sequence or structural similarity with UniProtKB:O14893 ribonucleoprotein complex assembly ; GO:0022618 | inferred from direct assay spliceosomal snRNP assembly ; GO:0000387 | inferred from direct assay flight behavior ; GO:0007629 | inferred from mutant phenotype spliceosomal complex ; GO:0005681 | inferred from electronic annotation with InterPro:IPR017364 SmD-containing SMN-Sm protein complex ; GO:0034730 | inferred from direct assay SMN-Gemin2 complex ; GO:0034718 | inferred from direct assay SMN complex ; GO:0032797 | inferred from genetic interaction with Gem3 cytoplasmic U snRNP body ; GO:0071254 | inferred from direct assay "Gem2, CG10419, dGem2" IPR017364:Gem-associated protein 2 CG10419 27-Aug-18 DroID_v2018_08 Drer\gemin2 Scer\YLR053C "Cele\col-122, Cele\smi-1" Xtro\gemin2 Mmus\Gemin2 "Hsap\SMAD4, Hsap\GEMIN2" "lethal,heat sensitive,gravitaxis defective,progressive,flight defective,short lived,partially lethal - majority die,some die during pupal stage" FBgn0034638 CG10433 - http://flybase.org/reports/FBgn0034638 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern defense response ; GO:0006952 | inferred from sequence or structural similarity regulation of female receptivity ; GO:0045924 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence model CG10433 - CG10433 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,viable" FBgn0025131 su(RpII140[Z36])S16 su(RpII140[Z36])S16 http://flybase.org/reports/FBgn0025131 - gene - - - "Z36[S16], su(RpII140[Z36])S16" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0010307 mod(r)2 modulator of rudimentary 2 http://flybase.org/reports/FBgn0010307 - gene - - - mod(r)2 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262694 Su(VGlut)B14 - http://flybase.org/reports/FBgn0262694 gene - - - "Su(VGlut)B14, B14" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0053056 CG33056 - http://flybase.org/reports/FBgn0053056 protein_coding_gene purine nucleoside binding ; GO:0001883 | inferred from sequence or structural similarity with HGNC:21257 purine nucleoside metabolic process ; GO:0042278 | inferred from sequence or structural similarity with HGNC:21257 cellular_component ; GO:0005575 | no biological data available "CG10517, CG33056" IPR002589:Macro domain CG33056 27-Aug-18 DroID_v2018_08 "Drer\zgc:113436, Drer\oard1" Scer\POA1 "Cele\F54G2.2, Cele\fbxb-37, Cele\W08F4.12" - Mmus\Oard1 Hsap\OARD1 "viable,visible" "trichogen cell,supernumerary" FBgn0044076 E(rst)I12 E(rst)I12 http://flybase.org/reports/FBgn0044076 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "I12, E(rst)I12" - - 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0262881 CG43236 - http://flybase.org/reports/FBgn0262881 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43236 - CG43236 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060619 l(3)S088712b lethal (3) S088712b http://flybase.org/reports/FBgn0060619 gene - - - "0887/12, l(3)S088712b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0267268 lncRNA:CR45704 - http://flybase.org/reports/FBgn0267268 non_protein_coding_gene - - - CR45704 - CR45704 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060910 l(3)S042834a lethal (3) S042834a http://flybase.org/reports/FBgn0060910 gene - - - "0428/34, l(3)S042834a" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0002820 ms(2)10R male sterile (2) 10R http://flybase.org/reports/FBgn0002820 - gene - - - ms(2)10R - - 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,recessive,female fertile" "spermatid axoneme,spermatid,spermatid & nucleus,Nebenkern derivative" FBgn0025772 l(3)89Ac lethal (3) 89Ac http://flybase.org/reports/FBgn0025772 - gene - - - l(3)89Ac - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0054000 CG34000 - http://flybase.org/reports/FBgn0054000 protein_coding_gene - - - "BP1067, CG34000" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267728 otk2 off-track2 http://flybase.org/reports/FBgn0267728 protein_coding_gene "coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway ; GO:1904929 | inferred from electronic annotation with InterPro:IPR033592 protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with otk protein homodimerization activity ; GO:0042803 | inferred from physical interaction with otk2 Wnt-protein binding ; GO:0017147 | inferred from physical interaction with Wnt2" Wnt signaling pathway ; GO:0016055 | inferred from electronic annotation with InterPro:IPR033592 convergent extension ; GO:0060026 | inferred from electronic annotation with InterPro:IPR033592 establishment of planar polarity ; GO:0001736 | inferred from electronic annotation with InterPro:IPR033592 imaginal disc-derived male genitalia morphogenesis ; GO:0048803 | inferred from genetic interaction with otk imaginal disc-derived female genitalia morphogenesis ; GO:0048804 | inferred from genetic interaction with otk internal genitalia morphogenesis ; GO:0035260 | inferred from genetic interaction with otk integral component of plasma membrane ; GO:0005887 | inferred from electronic annotation with InterPro:IPR033592 integral component of membrane ; GO:0016021 | inferred from sequence model "otk2, CG8964, CT25760, l(2)SH1639, l(2)SH2 1639" "IPR003598:Immunoglobulin subtype 2, IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold, IPR013098:Immunoglobulin I-set, IPR033592:Inactive tyrosine-protein kinase 7, IPR013106:Immunoglobulin V-set domain" CG8964 27-Aug-18 DroID_v2018_08 "Drer\vwa10.2, Drer\LOC100006752, Drer\LOC101884775, Drer\vwa11, Drer\si:ch73-380l3.2, Drer\zmp:0000001289, Drer\sc:d0284, Drer\si:dkey-14o18.6, Drer\si:ch211-286b5.9, Drer\si:ch211-1f22.3, Drer\LOC100535144, Drer\LOC100148735, Drer\zgc:172106, Drer\vwa7, Drer\spegb, Drer\scospondin, Drer\LOC100333105, Drer\hmcn2, Drer\ttnb, Drer\zgc:171470, Drer\cd22, Drer\LOC100333244, Drer\zmp:0000000971, Drer\si:ch211-171h4.5, Drer\vwa10.1, Drer\ptk7a, Drer\LOC101885775, Drer\ptk7b" - Cele\igcm-4 "Xtro\ceacam8, Xtro\MGC89178, Xtro\hmcn2, Xtro\ptk7" "Mmus\Hmcn2, Mmus\Hmcn1, Mmus\Vwa7, Mmus\Obscn, Mmus\Ptk7" "Hsap\SIGLEC15, Hsap\OBSCN, Hsap\PTK7, Hsap\VWA7, Hsap\HMCN1" FBgn0062646 EP531 EP531 http://flybase.org/reports/FBgn0062646 gene - - - "EP(2)0531, EP531" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038746 Surf6 Surfeit 6 http://flybase.org/reports/FBgn0038746 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from sequence or structural similarity with MGI:MGI:98447 RNA binding ; GO:0003723 | inferred from biological aspect of ancestor with PANTHER:PTN000372642 DNA binding ; GO:0003677 | inferred from biological aspect of ancestor with PANTHER:PTN000372642 ventral cord development ; GO:0007419 | inferred from mutant phenotype ribosomal small subunit biogenesis ; GO:0042274 | inferred from biological aspect of ancestor with PANTHER:PTN000372642 ribosome biogenesis ; GO:0042254 | inferred from sequence or structural similarity with MGI:MGI:98447 ribosomal large subunit biogenesis ; GO:0042273 | inferred from biological aspect of ancestor with PANTHER:PTN000372642 neurogenesis ; GO:0022008 | inferred from mutant phenotype nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000372642 nucleolus ; GO:0005730 | inferred from sequence or structural similarity with MGI:MGI:98447 cytosolic large ribosomal subunit ; GO:0022625 | inferred from biological aspect of ancestor with PANTHER:PTN000372642 "CG4510, Surf6" "IPR007019:Surfeit locus 6, IPR029190:Ribosomal RNA-processing protein 14/surfeit locus protein 6, C-terminal domain" CG4510 27-Aug-18 DroID_v2018_08 Drer\surf6 Scer\RRP14 Cele\ZK546.14 Xtro\surf6 Mmus\Surf6 Hsap\SURF6 "viable,fertile,lethal,neuroanatomy defective,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0011140 l(1)Q216 lethal (1) Q216 http://flybase.org/reports/FBgn0011140 FBgn0010210 gene - - - l(1)Q216 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0005669 e(mr) enhancer of morula http://flybase.org/reports/FBgn0005669 - gene - - - e(mr) - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0024691 fsf fruitless stimulation factor http://flybase.org/reports/FBgn0024691 - gene - - - fsf - - 27-Aug-18 DroID_v2018_08 - - - - - - "courtship behavior defective,male" FBgn0261975 CG42806 - http://flybase.org/reports/FBgn0261975 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42806 - CG42806 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265341 lncRNA:CR44295 - http://flybase.org/reports/FBgn0265341 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG44295, CR44295" - CR44295 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032205 CG4957 - http://flybase.org/reports/FBgn0032205 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000283242 CG4957 "IPR002876:Transcriptional regulator TACO1-like, IPR017856:Integrase, N-terminal zinc-binding domain-like, IPR029072:YebC-like, IPR026564:Transcriptional regulator TACO1-like, domain 3" CG4957 27-Aug-18 DroID_v2018_08 "Drer\LOC100534805, Drer\taco1" Scer\YGR021W Cele\taco-1 Xtro\taco1 Mmus\Taco1 Hsap\TACO1 viable FBgn0025475 prd::Mmus\Pax8 Pax8 http://flybase.org/reports/FBgn0025475 - engineered_fusion_gene - - - prd::Mmus\Pax8 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264794 lncRNA:CR44024 - http://flybase.org/reports/FBgn0264794 non_protein_coding_gene - - - CR44024 - CR44024 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0012001 tRNA:Val-CAC-2-4 transfer RNA:Valine-CAC 2-4 http://flybase.org/reports/FBgn0012001 "FBgn0003853, FBgn0011997, FBgn0051502, FBgn0060026" tRNA_gene GUG codon-amino acid adaptor activity ; GO:0033452 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033452 cytosol ; GO:0005829 | inferred by curator from GO:0033452 "CR31502, valine tRNA, tRNA[Val][[3b]], Val-3b, AE002699.trna1-ValCAC, tRNA:V3b, tRNA:V:CAC:AE002699-a, tRNA:val3b:84Dd, chr3R.trna74-ValCAC, tRNA:Val-CAC-2-4, tRNA:V3b:84Dd, tRNA-Val-CAC-2-4, GUG" - CR31502 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002385 l(3)93Da lethal (3) 93Da http://flybase.org/reports/FBgn0002385 - gene - - - "er1, l(3)er1, l(3)93Da" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,partially" FBgn0052114 CG32114 - http://flybase.org/reports/FBgn0052114 protein_coding_gene - - - CG32114 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033547 CG12935 - http://flybase.org/reports/FBgn0033547 protein_coding_gene - nervous system development ; GO:0007399 | inferred from mutant phenotype - CG12935 IPR026100:Transmembrane protein 223 CG12935 27-Aug-18 DroID_v2018_08 Drer\tmem223 - - Xtro\tmem223 Mmus\Tmem223 Hsap\TMEM223 viable DRSC07025 K -0.768590933 0.27342169 0.519999025 -0.233746873 1.771573807 1.230042146 FBgn0066319 24D1 24D1 http://flybase.org/reports/FBgn0066319 gene - - - 24D1 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0023492 Mst78D Mst78D http://flybase.org/reports/FBgn0023492 - gene - - - Mst78D - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259850 Su(Ste):CR42419 Su(Ste):CR42419 http://flybase.org/reports/FBgn0259850 non_protein_coding_gene - - - "Su(Ste):CR42419, CR42419" - CR42419 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0261974 snoRNA:Or-CD9b - http://flybase.org/reports/FBgn0261974 snoRNA_gene - - nucleoplasm ; GO:0005654 | inferred from direct assay "CR42805, DmOr_cd9b snoRNA, CR34567, snoRNA:Or-CD9b, orphan CD9b, snoRNA:Or-cd9b, CR34101, snmRNA:60Cb, Dmsnm60b, snm60, DmOrC/D_9b, Snm60b" - CR42805 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034827 Klp59D Kinesin-like protein at 59D http://flybase.org/reports/FBgn0034827 protein_coding_gene microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR001752 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001752 microtubule motor activity ; GO:0003777 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity ATPase activity ; GO:0016887 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity sperm axoneme assembly ; GO:0007288 | inferred from mutant phenotype microtubule-based movement ; GO:0007018 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 regulation of motile cilium assembly ; GO:1905503 | inferred from mutant phenotype kinesin complex ; GO:0005871 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 kinesin complex ; GO:0005871 | inferred from sequence or structural similarity "KLP59D, DmKlp59D, CG12192, Klp59D, KIF2A/B/C" "IPR001752:Kinesin motor domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG12192 27-Aug-18 DroID_v2018_08 "Drer\zgc:103670, Drer\kif2c" Scer\KIP3 Cele\klp-7 "Xtro\kif2c, Xtro\kif2a" "Mmus\Kif24, Mmus\Kif2b, Mmus\Kif2c, Mmus\Kif2a" "Hsap\KIF2A, Hsap\KIF2B, Hsap\KIF24, Hsap\KIF2C" viable FBgn0082372 EP2182 EP2182 http://flybase.org/reports/FBgn0082372 gene - - - EP2182 - - 27-Aug-18 DroID_v2018_08 - - - - - - "germline cell,male,embryonic/larval salivary gland" FBgn0265983 lncRNA:CR44762 - http://flybase.org/reports/FBgn0265983 non_protein_coding_gene - - - CR44762 - CR44762 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0028999 nerfin-1 nervous fingers 1 http://flybase.org/reports/FBgn0028999 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from mutant phenotype neuron development ; GO:0048666 | inferred from mutant phenotype - "CG13906, nerfin-1, Nerfin-1, Nerfin, nerfin" "IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG13906 27-Aug-18 DroID_v2018_08 "Drer\insm1b, Drer\insm1a" - Cele\egl-46 Xtro\insm2 "Mmus\Insm1, Mmus\Insm2" "Hsap\INSM2, Hsap\ZNF7, Hsap\ZNF707, Hsap\INSM1" "viable,lethal - all die before end of pupal stage,some die during pupal stage" "longitudinal connective,anterior commissure,posterior commissure,pCC neuron,intermediate longitudinal fascicle,lateral longitudinal fascicle,medial longitudinal fascicle" FBgn0266934 CR45385 - http://flybase.org/reports/FBgn0266934 pseudogene_attribute - - - CR45385 - CR45385 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002240 l(3)68Cb lethal (3) 68Cb http://flybase.org/reports/FBgn0002240 - gene - - - "l(3)C605, l(3)68Cb" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage,recessive,lethal" FBgn0262761 Mst77Y-12 Male-specific transcript 77Y 12 http://flybase.org/reports/FBgn0262761 nuclear_gene molecular_function ; GO:0003674 | no biological data available "spermatogenesis, exchange of chromosomal proteins ; GO:0035093 | inferred from sequence or structural similarity with Mst77F" chromatin ; GO:0000785 | inferred from sequence or structural similarity with Mst77F "Mst77Y-12, Mst77Y-12a" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038001 CG17404 - http://flybase.org/reports/FBgn0038001 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP149, CG17404" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG17404 27-Aug-18 DroID_v2018_08 "Drer\st14b, Drer\prss59.2" - "Cele\svh-1, Cele\try-3" - "Mmus\2210010C04Rik, Mmus\Cfd, Mmus\Ovch2, Mmus\Try5, Mmus\Egfbp2, Mmus\Prss2" "Hsap\PRSS3, Hsap\OVCH1, Hsap\CFD, Hsap\OVCH2, Hsap\KLK6" viable DRSC15234 E 0.076363876 0.484088478 1.428018162 1.882274061 0.161500743 -0.068919954 FBgn0028638 ifm(2)RU4 indirect flight muscle (2) RU4 http://flybase.org/reports/FBgn0028638 gene molecular_function ; GO:0003674 | no biological data available muscle organ development ; GO:0007517 | inferred from mutant phenotype polytene chromosome puff ; GO:0005703 | inferred from direct assay ifm(2)RU4 - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive,flight defective,fertile,viable" "wing,dorsal medial muscle,dorsal medial muscle & myofibril" FBgn0261732 EC2374 - http://flybase.org/reports/FBgn0261732 gene - - - EC2374 - - 27-Aug-18 DroID_v2018_08 - - - - - - "some die during embryonic stage,lethal - all die before end of embryonic stage" FBgn0052945 CG32945 - http://flybase.org/reports/FBgn0052945 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32945 - CG32945 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0044406 Scim21 Sensitized chromosome inheritance modifier 21 http://flybase.org/reports/FBgn0044406 gene - female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype - Scim21 - - 27-Aug-18 DroID_v2018_08 - - - - - - "meiotic cell cycle defective,dominant" FBgn0032974 CG3651 - http://flybase.org/reports/FBgn0032974 protein_coding_gene - - - CG3651 - CG3651 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0027207 l(1)G0394 lethal (1) G0394 http://flybase.org/reports/FBgn0027207 - gene - - - l(1)G0394 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,partially lethal - majority die,recessive" FBgn0013567 l(3)78Ac lethal (3) 78Ac http://flybase.org/reports/FBgn0013567 - gene - - - l(3)78Ac - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0053548 SmydA-8 "SET and MYND domain containing, arthropod-specific, member 8" http://flybase.org/reports/FBgn0053548 protein_coding_gene S-adenosylmethionine-dependent methyltransferase activity ; GO:0008757 | inferred from sequence or structural similarity with SGD:S000001250 histone deacetylase binding ; GO:0042826 | inferred from sequence or structural similarity with Smyd4-2 histone lysine methylation ; GO:0034968 | inferred from sequence or structural similarity with SGD:S000001250 negative regulation of gene expression ; GO:0010629 | inferred from sequence or structural similarity with Smyd4-2 nuclear chromatin ; GO:0000790 | inferred from sequence or structural similarity with SGD:S000001250 "Msta, EG:103B4.4, CG18033, CG32799, EG:103B4.5, CG32800, CG33548, MSTA, SmydA-8, msta" IPR001214:SET domain CG33548 27-Aug-18 DroID_v2018_08 "Drer\smyd2b, Drer\smyd3, Drer\smyd1a, Drer\smyd1b, Drer\smyd4, Drer\smyd2a" "Scer\SET5, Scer\SET6" - "Xtro\smyd4, Xtro\smyd5, Xtro\smyd1" "Mmus\Smyd3, Mmus\Smyd1, Mmus\Smyd2, Mmus\Smyd4, Mmus\Smyd5" "Hsap\SMYD5, Hsap\SMYD4, Hsap\SMYD1, Hsap\SMYD2, Hsap\SMYD3" viable FBgn0267770 asRNA:CR46101 - http://flybase.org/reports/FBgn0267770 non_protein_coding_gene - - - CR46101 - CR46101 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033708 CG8850 - http://flybase.org/reports/FBgn0033708 protein_coding_gene neurotransmitter:sodium symporter activity ; GO:0005328 | inferred from electronic annotation with InterPro:IPR000175 neurotransmitter transporter activity ; GO:0005326 | inferred from sequence or structural similarity with DAT transporter activity ; GO:0005215 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 cation:amino acid symporter activity ; GO:0005416 | inferred from sequence model amino acid transmembrane import ; GO:0044745 | inferred from sequence model neurotransmitter transport ; GO:0006836 | inferred from sequence or structural similarity with DAT transport ; GO:0006810 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 integral component of membrane ; GO:0016021 | inferred from sequence model "CG8850, DmNAT4" IPR000175:Sodium:neurotransmitter symporter CG8850 27-Aug-18 DroID_v2018_08 "Drer\slc6a19b, Drer\si:ch211-132b12.2, Drer\zgc:174946, Drer\si:ch211-132b12.6, Drer\si:ch211-132b12.3, Drer\si:ch211-132b12.1, Drer\slc6a8, Drer\slc6a16b, Drer\slc6a9, Drer\si:ch211-117c9.5, Drer\slc6a5, Drer\slc6a14, Drer\slc6a13l, Drer\slc6a15, Drer\slc6a4b, Drer\zgc:158225, Drer\slc6a1b, Drer\slc6a6b, Drer\slc6a17, Drer\slc6a11a, Drer\slc6a13, Drer\slc6a13, Drer\slc6a4a, Drer\slc6a6a, Drer\slc6a1a, Drer\slc6a18, Drer\slc6a19a.1, Drer\slc6a2, Drer\slc6a16a, Drer\slc6a1l" - "Cele\snf-7, Cele\dat-1, Cele\snf-5, Cele\mod-5, Cele\snf-12, Cele\snf-3, Cele\snf-2, Cele\snf-11, Cele\snf-9, Cele\snf-6" "Xtro\slc6a1, Xtro\slc6a8, Xtro\slc6a3, Xtro\slc6a12, Xtro\slc6a4, Xtro\slc6a17, Xtro\slc6a16, Xtro\slc6a9, Xtro\slc6a14.2, Xtro\slc6a7, Xtro\LOC100127682, Xtro\slc6a19, Xtro\slc6a6, Xtro\slc6a5, Xtro\slc6a2, Xtro\slc6a13, Xtro\slc6a15" "Mmus\Slc6a13, Mmus\Slc6a2, Mmus\Slc6a7, Mmus\Slc6a20a, Mmus\Slc6a6, Mmus\Slc6a4, Mmus\Slc6a3, Mmus\Slc6a5, Mmus\Slc6a14, Mmus\Slc6a8, Mmus\Slc6a19, Mmus\Slc6a1, Mmus\Slc6a12, Mmus\Slc6a11, Mmus\Slc6a9, Mmus\Slc6a15, Mmus\Slc6a18, Mmus\Slc6a17, Mmus\Slc6a20b" "Hsap\SLC6A17, Hsap\SLC6A12, Hsap\SLC6A9, Hsap\SLC6A8, Hsap\SLC6A2, Hsap\SLC6A11, Hsap\SLC6A1, Hsap\SLC6A13, Hsap\SLC6A20, Hsap\SLC6A19, Hsap\SLC6A6, Hsap\SLC6A15, Hsap\SLC6A14, Hsap\SLC6A3, Hsap\SLC6A18, Hsap\SLC6A5, Hsap\SLC6A4" FBgn0063780 accord2\pol accord2 element pol http://flybase.org/reports/FBgn0063780 transposable_element_gene - - - "qbert\pol, accord2\pol" "IPR026523:Paraneoplastic antigen Ma, IPR000477:Reverse transcriptase domain" - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030107 CG15370 - http://flybase.org/reports/FBgn0030107 protein_coding_gene - - - CG15370 - CG15370 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0005436 l(1)v47 lethal (1) v47 http://flybase.org/reports/FBgn0005436 - gene - - - "l(1)47, l(1)v47" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0086718 aga angina http://flybase.org/reports/FBgn0086718 gene - - - aga - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060417 l(3)S129310b lethal (3) S129310b http://flybase.org/reports/FBgn0060417 gene - - - "1293/10, l(3)S129310b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0016947 tilD touch insensitive larva D http://flybase.org/reports/FBgn0016947 - gene - - - tilD - - 27-Aug-18 DroID_v2018_08 - - - - - - "touch sensitivity defective,recessive,behavior defective,visible,somatic clone,paralytic" "macrochaeta,somatic clone,leg" FBgn0017423 anon-70Ca anon-70Ca http://flybase.org/reports/FBgn0017423 - gene - - - "t2, anon-70Ca" - - 27-Aug-18 DroID_v2018_08 - - - - - - " embryonic stage&&larval stage && pupal stage , egg stage | unfertilized egg " unfertilized egg

FBgn0038673 CG14286 - http://flybase.org/reports/FBgn0038673 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG14286, 14286" IPR029274:Protein of unknown function DUF4615 CG14286 27-Aug-18 DroID_v2018_08 Drer\zgc:112185 - - Xtro\c8orf33 Mmus\1110038F14Rik Hsap\C8orf33 "viable,fertile" FBgn0060694 l(3)S073015 lethal (3) S073015 http://flybase.org/reports/FBgn0060694 gene - - - "0730/15, l(3)S073015" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0067866 Mod(Prat:bw)3-9 Mod(Prat:bw)3-9 http://flybase.org/reports/FBgn0067866 gene - - - "Mod-3-9, Mod(Prat:bw)3-9" - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive" FBgn0033698 CG8858 - http://flybase.org/reports/FBgn0033698 protein_coding_gene protein complex scaffold ; GO:0032947 | inferred from electronic annotation with InterPro:IPR024372 molecular_function ; GO:0003674 | no biological data available proteasome assembly ; GO:0043248 | inferred from electronic annotation with InterPro:IPR024372 biological_process ; GO:0008150 | no biological data available nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:P38737 proteasome complex ; GO:0000502 | inferred from sequence or structural similarity with UniProtKB:P38737 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:P38737 CG8858 "IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold, IPR024372:Proteasome component Ecm29" CG8858 27-Aug-18 DroID_v2018_08 Drer\kiaa0368 Scer\ECM29 "Cele\D2045.2, Cele\H04D03.3" Xtro\kiaa0368 Mmus\AI314180 Hsap\KIAA0368 viable FBgn0038235 CG8461 - http://flybase.org/reports/FBgn0038235 protein_coding_gene - "cleavage involved in rRNA processing ; GO:0000469 | inferred from electronic annotation with InterPro:IPR009292 neurogenesis ; GO:0022008 | inferred from mutant phenotype maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ; GO:0000462 | inferred from biological aspect of ancestor with PANTHER:PTN000497661" 90S preribosome ; GO:0030686 | inferred from biological aspect of ancestor with PANTHER:PTN000497661 nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN000497661 CG8461 IPR009292:rRNA biogenesis protein RRP36 CG8461 27-Aug-18 DroID_v2018_08 Drer\rrp36 Scer\RRP36 Cele\T22H9.1 Xtro\klhdc3 Mmus\Rrp36 Hsap\RRP36 "lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0003495 spz spatzle http://flybase.org/reports/FBgn0003495 - protein_coding_gene Toll binding ; GO:0005121 | traceable author statement Toll binding ; GO:0005121 | non-traceable author statement growth factor activity ; GO:0008083 | inferred from mutant phenotype Toll binding ; GO:0005121 | inferred from physical interaction with Tl protein homodimerization activity ; GO:0042803 | inferred from direct assay Toll binding ; GO:0005121 | inferred from genetic interaction with Tl morphogen activity ; GO:0016015 | non-traceable author statement cytokine activity ; GO:0005125 | traceable author statement "innate immune response ; GO:0045087 | inferred from direct assay larval somatic muscle development ; GO:0007526 | inferred from mutant phenotype Toll signaling pathway ; GO:0008063 | inferred from direct assay Toll signaling pathway ; GO:0008063 | traceable author statement defense response to fungus ; GO:0050832 | inferred from mutant phenotype defense response ; GO:0006952 | inferred from mutant phenotype defense response ; GO:0006952 | traceable author statement immune response ; GO:0006955 | traceable author statement positive regulation of antifungal peptide biosynthetic process ; GO:0006967 | inferred from mutant phenotype response to fungus ; GO:0009620 | traceable author statement oocyte dorsal/ventral axis specification ; GO:0007310 | inferred from expression pattern dorsal/ventral axis specification ; GO:0009950 | traceable author statement dorsal/ventral axis specification ; GO:0009950 | inferred from genetic interaction with pip dorsal/ventral axis specification ; GO:0009950 | non-traceable author statement defense response to Gram-positive bacterium ; GO:0050830 | inferred from mutant phenotype motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype maternal specification of dorsal/ventral axis, oocyte, germ-line encoded ; GO:0007311 | traceable author statement innate immune response ; GO:0045087 | non-traceable author statement Toll signaling pathway ; GO:0008063 | non-traceable author statement antifungal humoral response ; GO:0019732 | inferred from mutant phenotype dorsal/ventral pattern formation ; GO:0009953 | inferred from direct assay embryonic axis specification ; GO:0000578 | non-traceable author statement regulation of Toll signaling pathway ; GO:0008592 | inferred from mutant phenotype defense response to Gram-positive bacterium ; GO:0050830 | inferred from direct assay positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria ; GO:0006965 | inferred from mutant phenotype positive regulation of protein complex assembly ; GO:0031334 | inferred from direct assay defense response to Gram-positive bacterium ; GO:0050830 | traceable author statement" extracellular region ; GO:0005576 | traceable author statement extracellular region ; GO:0005576 | inferred from direct assay protein complex ; GO:0043234 | inferred from physical interaction with Tl "Spz, spz, CG6134, mel(3)7, SPZ, Spz1, CT19282" "IPR029034:Cystine-knot cytokine, IPR032104:Spaetzle" CG6134 27-Aug-18 DroID_v2018_08 - - - - - - " oogenesis stage && adult stage | female , embryonic stage | 0-2 hr " ovary

"wild-type,immune response defective,recessive,lethal,maternal effect,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,some die during embryonic stage,dominant,partially lethal,neuroanatomy defective,locomotor rhythm defective,conditional,viable" "embryo,maternal effect,embryonic/first instar larval cuticle,ventral,dorsal,embryonic/larval somatic muscle,ventral furrow,supernumerary,ectopic,lateral,embryonic/larval fat body,embryonic/larval hemocoel" FBgn0003923 snRNA:U2:38ABb small nuclear RNA U2 at 38ABb http://flybase.org/reports/FBgn0003923 FBgn0003919 snRNA_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity" U2 snRNP ; GO:0005686 | inferred from sequence or structural similarity Cajal body ; GO:0015030 | inferred from direct assay "U2:38ABb, U2, dU2, U2 snRNA, U2-38ABb, snRNA[[1]], K6, Dm U2-141B, U2-141B, D.U2-4, 141B, U2 141B, snRNA-U2-141B, snRNA:U2:40AB, snRNA:U2, snRNA2, snRNA1, U2snRNA40AB, CR32878, U2snRNA, snRNA:U2:38ABb, U2:39AB, 38A U2, chr2L:19808533..19808709" - CR32878 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038098 CG7381 - http://flybase.org/reports/FBgn0038098 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CT22687, CG7381" IPR006149:EB domain CG7381 27-Aug-18 DroID_v2018_08 - - "Cele\D1044.7, Cele\pqn-25" - - - viable FBgn0265644 lncRNA:CR44451 - http://flybase.org/reports/FBgn0265644 non_protein_coding_gene - - - "CR44451, lincRNA.275" - CR44451 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039402 Vps2 Vacuolar protein sorting 2 http://flybase.org/reports/FBgn0039402 protein_coding_gene molecular_function ; GO:0003674 | no biological data available vacuolar transport ; GO:0007034 | inferred from electronic annotation with InterPro:IPR005024 endosome transport via multivesicular body sorting pathway ; GO:0032509 | inferred from mutant phenotype endosomal transport ; GO:0016197 | inferred from mutant phenotype ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway ; GO:0043162 | inferred from mutant phenotype regulation of Notch signaling pathway ; GO:0008593 | inferred from mutant phenotype negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from mutant phenotype negative regulation of Notch signaling pathway ; GO:0045746 | inferred from mutant phenotype multivesicular body ; GO:0005771 | colocalizes_with inferred from direct assay early endosome ; GO:0005769 | colocalizes_with inferred from direct assay ESCRT III complex ; GO:0000815 | inferred from sequence or structural similarity with SGD:S000004409 "NEST:bs02f06, Vps2, Did4, vps2, CG14542, dvps2, DmVPS2, Dvps2" IPR005024:Snf7 family CG14542 27-Aug-18 DroID_v2018_08 Drer\bc2 Scer\DID4 Cele\vps-2 Xtro\chmp2a Mmus\Chmp2a Hsap\CHMP2A "lethal,lethal - all die before end of embryonic stage,hypoplasia,somatic clone,hyperplasia,somatic clone - Minute background,increased cell death" "embryonic/larval brain,wing disc,somatic clone,somatic clone - Minute background,haltere disc,ventral thoracic disc,epithelium,epithelial cell,actin cytoskeleton | somatic clone - Minute background | third instar larval stage,nucleus | somatic clone - Minute background | third instar larval stage,eye,egg chamber,plasma membrane | somatic clone" DRSC14886 K 0.243924232 -0.808890626 0.86566227 -0.834529864 -2.064803496 -1.4775397 FBgn0266536 lncRNA:CR45097 - http://flybase.org/reports/FBgn0266536 non_protein_coding_gene - - - CR45097 - CR45097 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065176 l(3)SH010 lethal (3) SH010 http://flybase.org/reports/FBgn0065176 gene - - - "l(3)SH010, l(2)SH3 010" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0005014 dipp-5 defective in phototaxis plasticity 5 http://flybase.org/reports/FBgn0005014 - gene - - - dipp-5 - - 27-Aug-18 DroID_v2018_08 - - - - - - "neurophysiology defective,visual behavior defective,phototaxis defective" FBgn0034901 CG11300 - http://flybase.org/reports/FBgn0034901 protein_coding_gene - - - "BcDNA:LP08443, CG11300" - CG11300 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0020647 KrT95D Krueppel target at 95D http://flybase.org/reports/FBgn0020647 - protein_coding_gene - protein targeting to plasma membrane ; GO:0072661 | inferred from biological aspect of ancestor with PANTHER:PTN000998635 - "CG5405, KrT95D" IPR019381:Phosphofurin acidic cluster sorting protein 1 CG5405 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-126j24.1, Drer\pacs2, Drer\pacs1a" - Cele\tag-232 "Xtro\pacs2, Xtro\pacs1" "Mmus\Pacs2, Mmus\Pacs1" "Hsap\PACS1, Hsap\PACS2" "viable,fertile,partially lethal - majority die,visible" "trichogen cell,mesothoracic tergum" FBgn0052710 CG32710 - http://flybase.org/reports/FBgn0052710 protein_coding_gene - - - CG32710 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0053189 CG33189 - http://flybase.org/reports/FBgn0053189 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33189 - CG33189 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0015282 Rpt2 Regulatory particle triple-A ATPase 2 http://flybase.org/reports/FBgn0015282 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959, InterPro:IPR003960 ATPase activity ; GO:0016887 | inferred from sequence model TBP-class protein binding ; GO:0017025 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 proteasome-activating ATPase activity ; GO:0036402 | inferred from biological aspect of ancestor with PANTHER:PTN000553036" proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from mutant phenotype positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ; GO:0045899 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 ER-associated ubiquitin-dependent protein catabolic process ; GO:0030433 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred by curator from GO:0005838 "proteasome regulatory particle ; GO:0005838 | inferred from direct assay proteasome regulatory particle ; GO:0005838 | inferred from sequence or structural similarity with HGNC:9547 inferred from direct assay nuclear proteasome complex ; GO:0031595 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 cytosolic proteasome complex ; GO:0031597 | inferred from biological aspect of ancestor with PANTHER:PTN000553036 proteasome regulatory particle, base subcomplex ; GO:0008540 | inferred from sequence or structural similarity with SGD:S000002165 proteasome regulatory particle, base subcomplex ; GO:0008540 | inferred from direct assay" "pros26.4, S4, p56, dRpt2, Dm_Rpt2, DmP26S4, P26s4, CG5289, Pros26.4, Dm-S4-1, PSMC1, Rpt2, 5289" "IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR003960:ATPase, AAA-type, conserved site, IPR005937:26S proteasome subunit P45, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG5289 27-Aug-18 DroID_v2018_08 "Drer\psmc1a, Drer\psmc1b" Scer\RPT2 "Cele\C10G11.8, Cele\rpt-2" Xtro\psmc1 Mmus\Psmc1 Hsap\PSMC1 "meiotic cell cycle defective,male limited,lethal" "testis,spermatocyte" DRSC16799 IEK -2.739142906 -5.993688164 -2.727832802 -4.097045764 4.025543552 3.135853425 FBgn0063414 l(3)3450-I lethal (3) 3450-I http://flybase.org/reports/FBgn0063414 gene - - - l(3)3450-I - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0026395 Or23a Odorant receptor 23a http://flybase.org/reports/FBgn0026395 - protein_coding_gene "transmembrane signaling receptor activity ; GO:0004888 | inferred from sequence model olfactory receptor activity ; GO:0004984 | non-traceable author statement olfactory receptor activity ; GO:0004984 | inferred from direct assay odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | non-traceable author statement inferred by curator from GO:0004888,GO:0007608" detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from direct assay sensory perception of smell ; GO:0007608 | non-traceable author statement sensory perception of smell ; GO:0007608 | inferred from expression pattern dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a integral component of membrane ; GO:0016021 | inferred from sequence model integral component of membrane ; GO:0016021 | inferred from direct assay neuronal cell body ; GO:0043025 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 integral component of membrane ; GO:0016021 | non-traceable author statement dendrite ; GO:0030425 | inferred from direct assay "23a, DOR64, DOR64, AN5, CG9880, 23A.1, Dor64, AN5, dor64, DOR23A.1, Or64, Or23A.1, Or23a, or23a" "IPR004117:Olfactory receptor, insect" CG9880 27-Aug-18 DroID_v2018_08 - - - - - - adult stage " sensory neuron &&of maxillary palpus

, sensory neuron &&of antennal segment 3

" FBgn0036496 CG7804 - http://flybase.org/reports/FBgn0036496 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity - - "cg7804, CG7804" IPR000504:RNA recognition motif domain CG7804 27-Aug-18 DroID_v2018_08 "Drer\tardbp, Drer\tardbpl" Scer\DDR48 "Cele\sqd-1, Cele\tdp-1" Xtro\tardbp Mmus\Tardbp Hsap\TARDBP "viable,partially lethal - majority die,some die during pupal stage" FBgn0046636 anon-38D.9 anon-38D.9 http://flybase.org/reports/FBgn0046636 gene - - - "38D.9, anon-38D.9" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0017562 Oef2 oe1 binding factor 2 http://flybase.org/reports/FBgn0017562 - gene DNA binding ; GO:0003677 | inferred from direct assay - nucleus ; GO:0005634 | inferred from direct assay "OEF2, Oef2" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0010564 l(2)04012a lethal (2) 04012a http://flybase.org/reports/FBgn0010564 - gene - - - "l(2)04012, 4012, l(2)04012a" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0001625 l(1)dn2 lethal (1) discs normal 2 http://flybase.org/reports/FBgn0001625 - gene - - - "l(1)d.norm.-2, l(1)dn2" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0039212 Syx18 Syntaxin 18 http://flybase.org/reports/FBgn0039212 protein_coding_gene SNAP receptor activity ; GO:0005484 | inferred from sequence or structural similarity with Syx17 SNAP receptor activity ; GO:0005484 | inferred from sequence or structural similarity SNARE binding ; GO:0000149 | inferred from sequence or structural similarity with Syx17 "retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | inferred from biological aspect of ancestor with PANTHER:PTN000409677 neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from biological aspect of ancestor with PANTHER:PTN000409677 neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype" cell cortex ; GO:0005938 | inferred from direct assay neuromuscular junction ; GO:0031594 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN000409677 SNARE complex ; GO:0031201 | inferred from biological aspect of ancestor with PANTHER:PTN000409677 SNARE complex ; GO:0031201 | inferred from sequence or structural similarity with Syx17 "DmSyx18, Ufe1/Syntaxin 18, Dm Ufe1, CG13626, Syx18, Syx, gtx" "IPR000727:Target SNARE coiled-coil homology domain, IPR019529:SNARE-complex protein Syntaxin-18, N-terminal" CG13626 27-Aug-18 DroID_v2018_08 "Drer\cox5aa, Drer\stx18, Drer\cox5ab" Scer\UFE1 "Cele\syx-18, Cele\cco-2" "Xtro\stx18, Xtro\cox5a" "Mmus\Stx18, Mmus\Cox5a" Hsap\STX18 "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,neuroanatomy defective,neurophysiology defective,lethal - all die before end of second instar larval stage,some die during second instar larval stage,viable,visible,partially lethal - majority die,some die during pupal stage" "NMJ bouton,endomembrane system & embryonic/larval somatic muscle,embryonic/larval somatic muscle,subsynaptic reticulum,neuromuscular junction,embryonic/larval neuromuscular junction,subsynaptic reticulum | ectopicC57,mesothoracic tergum" DRSC14628 I 4.24921079 0.79566397 1.14461768 -0.997504847 -0.23413268 -0.447899628 FBgn0000779 fs(1)A1459 female sterile (1) A1459 http://flybase.org/reports/FBgn0000779 - gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | traceable author statement cellular_component ; GO:0005575 | no biological data available "fs(1)1459, fs(1)M23, fs(1)K499, fs(1)M2, fs(1)A1459" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,maternal effect,female sterile,recessive,heat sensitive,non-rescuable maternal effect" "gastrula embryo,maternal effect,blastoderm embryo" FBgn0028475 Hrd3 HMG-coA reductase degradation 3 http://flybase.org/reports/FBgn0028475 protein_coding_gene - - - "BcDNA:LD23587, HRD3, CG10221, Hrd3" IPR006597:Sel1-like repeat CG10221 27-Aug-18 DroID_v2018_08 "Drer\LOC559843, Drer\sel1l, Drer\lrp2bp, Drer\LOC101886164, Drer\zgc:158257" "Scer\ACK1, Scer\SHC1, Scer\SKT5, Scer\HRD3" Cele\sel-1 "Xtro\lrp2bp, Xtro\sel1l3, Xtro\sel1l" "Mmus\Lrp2bp, Mmus\Sel1l2, Mmus\0610009O20Rik, Mmus\Sel1l3, Mmus\Sel1l" "Hsap\SEL1L3, Hsap\LRP2BP, Hsap\SEL1L2, Hsap\SEL1L, Hsap\KIAA0141" "body color defective,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0004623 Gbeta76C G protein beta-subunit 76C http://flybase.org/reports/FBgn0004623 FBgn0016651 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with Gγ30A phototransduction ; GO:0007602 | inferred from direct assay rhodopsin mediated signaling pathway ; GO:0016056 | inferred from mutant phenotype deactivation of rhodopsin mediated signaling ; GO:0016059 | traceable author statement G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from direct assay phototransduction ; GO:0007602 | inferred from mutant phenotype activation of phospholipase C activity ; GO:0007202 | inferred from mutant phenotype deactivation of rhodopsin mediated signaling ; GO:0016059 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay rhabdomere ; GO:0016028 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay rhabdomere ; GO:0016028 | traceable author statement heterotrimeric G-protein complex ; GO:0005834 | inferred from direct assay "Gbeta76C, Gbe, Gbeta, G[q], Gbetae, DGqbeta, G[[beta]]e, gbe, G[[beta]], Gbeta[[e]], Gqbeta, CG8770, Galpha76C, Gbeta{e}, eye Gbeta, eGbeta, G[[beta76C]], G&bgr76C, Gbeta76c" "IPR017986:WD40-repeat-containing domain, IPR001632:G-protein, beta subunit, IPR001680:WD40 repeat, IPR016346:Guanine nucleotide-binding protein, beta subunit, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat" CG8770 27-Aug-18 DroID_v2018_08 "Drer\gnb1a, Drer\gnb5a, Drer\gnb3a, Drer\gnb3b, Drer\gnb4a, Drer\gnb4b, Drer\gnb5b, Drer\gnb2, Drer\gnb1b" Scer\STE4 "Cele\gpb-2, Cele\gpb-1, Cele\npp-20" "Xtro\gnb5, Xtro\gnb1, Xtro\gnb3, Xtro\gnb4" "Mmus\Gnb3, Mmus\Gnb2, Mmus\Gnb4, Mmus\Gnb1" "Hsap\GNB5, Hsap\GNB4, Hsap\GNB1, Hsap\GNB3, Hsap\GNB2" adult stage " adult head

, eye

" adult stage " eye

, photoreceptor cell

, medulla

, lamina

" "wild-type,neurophysiology defective,viable" photoreceptor cell FBgn0051365 CG31365 - http://flybase.org/reports/FBgn0051365 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 "CG4639, CG31365" "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type" CG31365 27-Aug-18 DroID_v2018_08 "Drer\zbtb24, Drer\zbtb8b, Drer\zbtb46, Drer\mynn, Drer\zbtb16b, Drer\zbtb17, Drer\zbtb18, Drer\hic2, Drer\zbtb16a, Drer\hic1, Drer\zbtb14, Drer\hic1l, Drer\zbtb49, Drer\bcl6ab, Drer\zbtb7a, Drer\zbtb1" Scer\ZAP1 "Cele\unc-98, Cele\klf-3" "Xtro\zbtb49, Xtro\zbtb18, Xtro\gzf1, Xtro\zbtb26, Xtro\zbtb7c, Xtro\hic2, Xtro\znf630, Xtro\zbtb11, Xtro\zbtb3, Xtro\bcl6, Xtro\hic1, Xtro\zbtb7b, Xtro\znf238.2, Xtro\zbtb14, Xtro\zbtb40, Xtro\zbtb8b" "Mmus\Zbtb26, Mmus\Zscan4d, Mmus\Zbtb7b, Mmus\Bcl6b, Mmus\Zfp719, Mmus\Zbtb7c, Mmus\Zbtb46, Mmus\Zbtb17, Mmus\Zscan4c, Mmus\Hic2, Mmus\Bcl6, Mmus\Zfp131, Mmus\Zbtb14, Mmus\Zbtb18, Mmus\Zbtb49, Mmus\Zbtb3, Mmus\Zbtb24, Mmus\Mynn, Mmus\Zfp341, Mmus\Zbtb7a, Mmus\Zbtb42" "Hsap\ZBTB48, Hsap\ZBTB8B, Hsap\HIC2, Hsap\ZBTB17, Hsap\ZBTB18, Hsap\ZBTB3, Hsap\ZBTB16, Hsap\ZBTB7A, Hsap\GZF1, Hsap\ZNF302, Hsap\ZNF341, Hsap\ZBTB43, Hsap\ZBTB42, Hsap\BCL6, Hsap\ZBTB46, Hsap\MYNN, Hsap\ZBTB49, Hsap\ZBTB24, Hsap\ZNF131, Hsap\ZBTB7C, Hsap\ZBTB11, Hsap\ZBTB14, Hsap\ZBTB7B, Hsap\ZBTB5, Hsap\BCL6B, Hsap\ZNF83, Hsap\ZBTB26, Hsap\ZBTB2" viable FBgn0060358 l(3)S140612 lethal (3) S140612 http://flybase.org/reports/FBgn0060358 gene - - - "1406/12, l(3)S140612" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0039681 CG7582 - http://flybase.org/reports/FBgn0039681 protein_coding_gene - - integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR012506 CG7582 IPR012506:YhhN-like CG7582 27-Aug-18 DroID_v2018_08 "Drer\tmem86a, Drer\tmem86b" - Cele\M176.4 Xtro\tmem86a "Mmus\Tmem86a, Mmus\Tmem86b" "Hsap\TMEM86A, Hsap\TMEM86B" viable FBgn0259196 CG42300 - http://flybase.org/reports/FBgn0259196 protein_coding_gene SUMO transferase activity ; GO:0019789 | inferred from electronic annotation with InterPro:IPR026846 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR004181 double-strand break repair via homologous recombination ; GO:0000724 | inferred from electronic annotation with InterPro:IPR026846 Smc5-Smc6 complex ; GO:0030915 | inferred from electronic annotation with InterPro:IPR026846 "CG42300, CG32584, CG18620" "IPR004181:Zinc finger, MIZ-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR026846:E3 SUMO-protein ligase Nse2 (Mms21)" CG42300 27-Aug-18 DroID_v2018_08 Drer\nsmce2 Scer\MMS21 Cele\ZK1248.11 - Mmus\Nsmce2 Hsap\NSMCE2 "viable,visible,fertile" tormogen cell FBgn0030932 Ggt-1 gamma-glutamyl transpeptidase http://flybase.org/reports/FBgn0030932 protein_coding_gene glutathione hydrolase activity ; GO:0036374 | inferred from sequence or structural similarity with HGNC:4250 inferred from direct assay glutathione catabolic process ; GO:0006751 | inferred from electronic annotation with InterPro:IPR000101 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern glutathione metabolic process ; GO:0006749 | inferred from direct assay response to light stimulus ; GO:0009416 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from direct assay "Ggt-1, GGT-1, CG6461" "IPR000101:Gamma-glutamyltranspeptidase, IPR029055:Nucleophile aminohydrolases, N-terminal" CG6461 27-Aug-18 DroID_v2018_08 "Drer\ggt1a, Drer\si:ch73-236c18.3, Drer\ggt5a, Drer\ggt1b, Drer\si:ch73-59p9.2, Drer\si:dkey-222h21.12, Drer\ggt5b, Drer\LOC103909498, Drer\ggt1l2.2" Scer\ECM38 "Cele\C53D5.5, Cele\Y97E10AR.2, Cele\H14N18.4, Cele\T19H12.6, Cele\Y7A9A.1, Cele\T03D8.6" "Xtro\ggt5, Xtro\ggt7, Xtro\ggt1" "Mmus\Ggt1, Mmus\Ggt5, Mmus\Ggt7, Mmus\Ggt6" "Hsap\GGT1, Hsap\GGTLC2, Hsap\GGT2, Hsap\GGT6, Hsap\GGT7, Hsap\GGT5, Hsap\GGTLC1" partially lethal - majority die FBgn0024638 l(2)k13525 lethal (2) k13525 http://flybase.org/reports/FBgn0024638 - gene - - - "135/25, l(2)k13525" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" imaginal disc FBgn0036705 CG13723 - http://flybase.org/reports/FBgn0036705 protein_coding_gene - - - CG13723 - CG13723 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0036317 CG10948 - http://flybase.org/reports/FBgn0036317 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity - - "CT30663, cg10948, CG10948" "IPR000504:RNA recognition motif domain, IPR034140:Ecto-NOX disulfide-thiol exchanger, RNA recognition motif" CG10948 27-Aug-18 DroID_v2018_08 "Drer\enox1, Drer\enox2" - - Xtro\enox1 "Mmus\Enox2, Mmus\Enox1" "Hsap\ENOX2, Hsap\ENOX1" "fertile,viable,lethal,partially lethal - majority die" FBgn0038507 CG5863 - http://flybase.org/reports/FBgn0038507 protein_coding_gene aspartic-type endopeptidase activity ; GO:0004190 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 protein autoprocessing ; GO:0016540 | inferred from electronic annotation with InterPro:IPR033145 proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 protein catabolic process ; GO:0030163 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 - CG5863 "IPR001461:Aspartic peptidase A1 family, IPR001969:Aspartic peptidase, active site, IPR033145:Cathepsin E, IPR021109:Aspartic peptidase domain, IPR033121:Peptidase family A1 domain" CG5863 27-Aug-18 DroID_v2018_08 "Drer\ctsd, Drer\zgc:103530, Drer\nots, Drer\zgc:63831, Drer\ren" "Scer\YPS5, Scer\BAR1, Scer\YPS6, Scer\MKC7, Scer\YPS1, Scer\YGL258W-A, Scer\PEP4, Scer\YPS3, Scer\YPS7" "Cele\asp-9, Cele\asp-18, Cele\asp-12, Cele\asp-1, Cele\asp-13, Cele\asp-4, Cele\asp-10, Cele\asp-19, Cele\asp-8, Cele\asp-14, Cele\asp-17, Cele\asp-6, Cele\asp-3, Cele\asp-15, Cele\asp-7, Cele\asp-16, Cele\asp-5, Cele\asp-2" "Xtro\ren, Xtro\ctse, Xtro\ctsd, Xtro\LOC496913, Xtro\pgc, Xtro\bace1, Xtro\napsa, Xtro\bace2, Xtro\pga4" "Mmus\Bace2, Mmus\Ctsd, Mmus\Bace1, Mmus\Cym, Mmus\Ctse, Mmus\Pgc, Mmus\Ren1, Mmus\Napsa, Mmus\Ren2, Mmus\Pga5" "Hsap\BACE1, Hsap\PGC, Hsap\PGA4, Hsap\REN, Hsap\PGA5, Hsap\NAPSA, Hsap\CTSE, Hsap\CTSD, Hsap\BACE2, Hsap\PGA3" "viable,fertile" FBgn0050237 tRNA:Gln-CTG-1-1 transfer RNA:Glutamine-CTG 1-1 http://flybase.org/reports/FBgn0050237 tRNA_gene CAG codon-amino acid adaptor activity ; GO:0033428 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033428 cytosol ; GO:0005829 | inferred by curator from GO:0033428 "AE002787.trna14-GlnCTG, tRNA:Q:CTG:AE002787, CR30237, chr2R.trna73-GlnCTG, tRNA:Gln-CTG-1-1, tRNA:CR30237, tRNA-Gln-CTG-1-1, CAG" - CR30237 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0261535 l(2)34Fd lethal (2) 34Fd http://flybase.org/reports/FBgn0261535 protein_coding_gene - - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012580 "CG7516, l(2)34Fd, l(2)br15, br15, A4, BG:DS01068.6" "IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR012580:NUC153, IPR017986:WD40-repeat-containing domain" CG7516 27-Aug-18 DroID_v2018_08 Drer\nol10 Scer\ENP2 Cele\nol-10 Xtro\nol10 Mmus\Nol10 Hsap\NOL10 FBgn0003683 term terminus http://flybase.org/reports/FBgn0003683 FBgn0036792 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - "ter, Term, CG4216, Bsg75C, term" IPR013087:Zinc finger C2H2-type CG4216 27-Aug-18 DroID_v2018_08 - Scer\FUS1 "Cele\edc-3, Cele\nhr-45" - Mmus\Aoc1 - FBgn0039833 CG15564 - http://flybase.org/reports/FBgn0039833 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG15564 - CG15564 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0261678 M(2)59B Minute (2) 59B http://flybase.org/reports/FBgn0261678 gene - - - "M(2)59B, RpL23" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034132 S-Lap8 Sperm-Leucylaminopeptidase 8 http://flybase.org/reports/FBgn0034132 protein_coding_gene "aminopeptidase activity ; GO:0004177 | inferred from electronic annotation with InterPro:IPR000819, InterPro:IPR008283, InterPro:IPR011356 metalloexopeptidase activity ; GO:0008235 | inferred from electronic annotation with InterPro:IPR011356 manganese ion binding ; GO:0030145 | inferred from electronic annotation with InterPro:IPR011356" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000819, InterPro:IPR008283" cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR011356 "anon-WO0140519.41, CG4439, S-Lap8, S-LAP 8" "IPR000819:Peptidase M17, leucyl aminopeptidase, C-terminal, IPR008283:Peptidase M17, leucyl aminopeptidase, N-terminal, IPR011356:Peptidase M17, leucine aminopeptidase/peptidase B" CG4439 27-Aug-18 DroID_v2018_08 "Drer\zgc:152830, Drer\rfwd2, Drer\npepl1, Drer\lap3" - "Cele\lap-1, Cele\lap-2" "Xtro\rfwd2, Xtro\lap3" "Mmus\Rfwd2, Mmus\Npepl1, Mmus\Lap3" "Hsap\NPEPL1, Hsap\LAP3" viable DRSC21372 K 0.439770231 0.398592919 0.089189963 -0.980274059 0.904633889 1.558873231 FBgn0032120 CG33298 - http://flybase.org/reports/FBgn0032120 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR006539 magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR006539 phospholipid-translocating ATPase activity ; GO:0004012 | inferred from biological aspect of ancestor with PANTHER:PTN000642368 phospholipid-translocating ATPase activity ; GO:0004012 | inferred from sequence or structural similarity with SGD:S000000024 intracellular protein transport ; GO:0006886 | inferred from genetic interaction with Osbp phospholipid translocation ; GO:0045332 | inferred from sequence or structural similarity with SGD:S000000024 response to endoplasmic reticulum stress ; GO:0034976 | inferred from mutant phenotype Golgi organization ; GO:0007030 | inferred from genetic interaction with Osbp "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR001757, InterPro:IPR006539 integral component of membrane ; GO:0016021 | inferred from sequence model plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000642368" "CG18419, CG13112, CG33298, DmCG33298" "IPR001757:P-type ATPase, IPR006539:P-type ATPase, subfamily IV, IPR008250:P-type ATPase, A domain, IPR018303:P-type ATPase, phosphorylation site, IPR023214:HAD-like domain, IPR023299:P-type ATPase, cytoplasmic domain N, IPR032630:P-type ATPase, C-terminal, IPR032631:P-type ATPase, N-terminal" CG33298 27-Aug-18 DroID_v2018_08 "Drer\atp8b4, Drer\atp8a1, Drer\atp8a2, Drer\atp10b, Drer\atp8b3, Drer\atp8b5b, Drer\atp8b1, Drer\atp11c, Drer\atp10a, Drer\atp11a, Drer\atp10d, Drer\atp8b5a" "Scer\DNF2, Scer\DNF3, Scer\DRS2, Scer\DNF1" "Cele\tat-4, Cele\tat-2, Cele\tat-3" "Xtro\atp8b3, Xtro\atp10a, Xtro\atp11c, Xtro\atp11a, Xtro\atp8b1, Xtro\LOC100490503, Xtro\atp11b, Xtro\atp8b4, Xtro\atp8a1, Xtro\atp10d" "Mmus\Atp8a1, Mmus\Atp10b, Mmus\Atp11a, Mmus\Atp11b, Mmus\Atp11c, Mmus\Atp10d, Mmus\Atp8b3, Mmus\Atp8a2, Mmus\Atp8b2, Mmus\Atp8b4, Mmus\Atp10a, Mmus\Atp8b1, Mmus\Atp8b5" "Hsap\ATP11B, Hsap\ATP10B, Hsap\ATP8A2, Hsap\ATP8B4, Hsap\ATP8B1, Hsap\ATP10A, Hsap\ATP8B3, Hsap\ATP11C, Hsap\ATP10D, Hsap\ATP8A1, Hsap\ATP11A, Hsap\ATP8B2" viable DRSC02672 IK 1.613799992 0.10515359 -0.17819812 0.11138554 1.739709757 0.726226242 FBgn0265958 lncRNA:CR44745 - http://flybase.org/reports/FBgn0265958 non_protein_coding_gene - - - CR44745 - CR44745 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031454 HemK2 - http://flybase.org/reports/FBgn0031454 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR002052 S-adenosylmethionine-dependent methyltransferase activity ; GO:0008757 | inferred from biological aspect of ancestor with PANTHER:PTN000430779 protein methyltransferase activity ; GO:0008276 | inferred from biological aspect of ancestor with PANTHER:PTN000430810 methylation ; GO:0032259 | inferred from electronic annotation with InterPro:IPR002052 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000430779 "CG32951, CG9960, Dromel_CG9960_CG9958_FBtr007773_snapin_mORF, DAMT, damt" "IPR002052:DNA methylase, N-6 adenine-specific, conserved site, IPR004557:Eukaryotic/archaeal PrmC-related, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase, IPR007848:Methyltransferase small domain" CG9960 27-Aug-18 DroID_v2018_08 Drer\n6amt1 "Scer\MTQ1, Scer\MTQ2" Cele\mtq-2 Xtro\n6amt1 "Mmus\Hemk1, Mmus\N6amt1" "Hsap\HEMK1, Hsap\N6AMT1" "lethal - all die before end of pupal stage,some die during pupal stage,neurophysiology defective" FBgn0011485 l(3)neo55 lethal (3) neo55 http://flybase.org/reports/FBgn0011485 - gene - - - l(3)neo55 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0030506 DNAlig4 Ligase4 http://flybase.org/reports/FBgn0030506 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000977, InterPro:IPR012310, InterPro:IPR029710 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR012308, InterPro:IPR029710 protein binding ; GO:0005515 | inferred from physical interaction with XRCC4 DNA ligase (ATP) activity ; GO:0003910 | inferred from biological aspect of ancestor with PANTHER:PTN000048695 DNA ligase (ATP) activity ; GO:0003910 | inferred from sequence or structural similarity with HGNC:6601 inferred from sequence or structural similarity with SGD:S000005531" "DNA biosynthetic process ; GO:0071897 | inferred from electronic annotation with InterPro:IPR000977 DNA recombination ; GO:0006310 | inferred from electronic annotation with InterPro:IPR000977, InterPro:IPR012308, InterPro:IPR012309, InterPro:IPR012310 DNA ligation involved in DNA repair ; GO:0051103 | inferred from biological aspect of ancestor with PANTHER:PTN000048695 telomere maintenance ; GO:0000723 | inferred from genetic interaction with tefu double-strand break repair via nonhomologous end joining ; GO:0006303 | inferred from mutant phenotype nucleotide-excision repair, DNA gap filling ; GO:0006297 | inferred from biological aspect of ancestor with PANTHER:PTN000048698 response to ionizing radiation ; GO:0010212 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000048695 DNA ligase IV complex ; GO:0032807 | inferred from biological aspect of ancestor with PANTHER:PTN000048698 DNA-dependent protein kinase-DNA ligase 4 complex ; GO:0005958 | inferred from biological aspect of ancestor with PANTHER:PTN000825456 "lig4, RE37186, CG12176, Lig4, ligIV, ligaseIV" "IPR000977:DNA ligase, ATP-dependent, IPR001357:BRCT domain, IPR012309:DNA ligase, ATP-dependent, C-terminal, IPR012310:DNA ligase, ATP-dependent, central, IPR012340:Nucleic acid-binding, OB-fold, IPR029710:DNA ligase 4, IPR012308:DNA ligase, ATP-dependent, N-terminal" CG12176 27-Aug-18 DroID_v2018_08 Drer\lig4 Scer\DNL4 "Cele\K07C5.3, Cele\Y73B6BL.14, Cele\lig-4" Xtro\lig4 Mmus\Lig4 Hsap\LIG4 "radiation sensitive,viable,fertile,rescuable maternal effect" FBgn0037177 CG14454 - http://flybase.org/reports/FBgn0037177 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CT34135, BcDNA:RE01153, CG14454" - CG14454 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0050096 CG30096 - http://flybase.org/reports/FBgn0050096 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG30096 - CG30096 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" DRSC21744 K 0.241655209 -0.122638804 -0.138504805 -0.712918551 1.889958821 0.966306003 FBgn0001698 l(1)ESHS19 lethal (1) ESHS19 http://flybase.org/reports/FBgn0001698 - gene - - - l(1)ESHS19 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0267076 asRNA:CR45520 - http://flybase.org/reports/FBgn0267076 non_protein_coding_gene - - - CR45520 - CR45520 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032023 CG14274 - http://flybase.org/reports/FBgn0032023 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - CG14274 - CG14274 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0062574 Mod(var)E1261 Mod(var)E1261 http://flybase.org/reports/FBgn0062574 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "E1261, Mod(var)E1261" - - 27-Aug-18 DroID_v2018_08 - - - - - - "enhancer of variegation,recessive,dominant,non-enhancer of variegation,non-suppressor of variegation,partially lethal - majority die" FBgn0053397 5SrRNA:CR33397 5SrRNA:CR33397 http://flybase.org/reports/FBgn0053397 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33397, 5SrRNA:CR33397" - CR33397 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259995 CG40169 - http://flybase.org/reports/FBgn0259995 protein_coding_gene - - - "anon-38C.20, CG40169, 38C.20" - - 27-Aug-18 DroID_v2018_08 - - - - - - DRSC01766 I -1.530770784 0.787159639 -0.355660539 0.129055649 -1.191664174 -0.781883301 FBgn0030334 Karl Karl http://flybase.org/reports/FBgn0030334 protein_coding_gene molecular_function ; GO:0003674 | no biological data available imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG4139, Karl, karl" IPR012674:Calycin CG4139 27-Aug-18 DroID_v2018_08 "Drer\apoda.1, Drer\apodb, Drer\apoda.2" - Cele\lpr-4 - Mmus\Apod Hsap\APOD viable FBgn0267756 lncRNA:CR46087 - http://flybase.org/reports/FBgn0267756 non_protein_coding_gene - - - "CR46087, lincRNA.874" - CR46087 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0003250 Rh4 Rhodopsin 4 http://flybase.org/reports/FBgn0003250 - protein_coding_gene G-protein coupled photoreceptor activity ; GO:0008020 | inferred from direct assay G-protein coupled photoreceptor activity ; GO:0008020 | inferred from sequence or structural similarity G-protein coupled photoreceptor activity ; GO:0008020 | non-traceable author statement G-protein coupled photoreceptor activity ; GO:0008020 | traceable author statement "visual perception ; GO:0007601 | inferred from electronic annotation with InterPro:IPR000856 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR000856 detection of UV ; GO:0009589 | traceable author statement phototransduction, UV ; GO:0007604 | traceable author statement phototransduction, UV ; GO:0007604 | non-traceable author statement phototransduction, UV ; GO:0007604 | inferred from direct assay G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity phototransduction ; GO:0007602 | non-traceable author statement" "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR000856, InterPro:IPR017452 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity" "Rh4, rh4, CG9668, Rh, FBgn0003250, DMELRH4, Dm Rh4, RH4" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR000856:Opsin RH3/RH4, IPR017452:GPCR, rhodopsin-like, 7TM, IPR027430:Visual pigments (opsins) retinal binding site" CG9668 27-Aug-18 DroID_v2018_08 "Drer\opn4xb, Drer\rgra, Drer\opn1mw3, Drer\opn6b, Drer\opn4xa, Drer\valopb, Drer\rho, Drer\opn4a, Drer\opn6a, Drer\opn1mw1, Drer\tmtops3a, Drer\parapinopsinb, Drer\opn7a, Drer\opn7c, Drer\valopa, Drer\opn3, Drer\parietopsin, Drer\exorh, Drer\rrh, Drer\opn9, Drer\opn1sw1, Drer\opn8b, Drer\opn1lw1, Drer\opn4.1, Drer\opn7b, Drer\opn1sw2, Drer\rhol, Drer\opn7d, Drer\opn4b, Drer\opn8c, Drer\tmtops3b, Drer\tmtopsb, Drer\tmtops2b, Drer\rgrb, Drer\tmtops2a, Drer\opn1mw4, Drer\opn1lw2, Drer\opn5" - "Cele\nmur-3, Cele\sro-1" "Xtro\LOC100485437, Xtro\tmtops.2, Xtro\tmtops, Xtro\LOC100485989, Xtro\LOC100124934, Xtro\rho, Xtro\opn1lw, Xtro\rrh, Xtro\opn1sw, Xtro\opn5" "Mmus\Opn1mw, Mmus\Opn5, Mmus\Rrh, Mmus\Opn1sw, Mmus\Opn4, Mmus\Rgr, Mmus\Rho, Mmus\Opn3" "Hsap\RGR, Hsap\OPN1MW3, Hsap\OPN3, Hsap\RRH, Hsap\OPN4, Hsap\RHO, Hsap\OPN5, Hsap\OPN1MW2, Hsap\OPN1LW, Hsap\OPN1MW, Hsap\OPN1SW" " adult stage , pupal stage | late , larval stage " " eye

, adult head

, Bolwig's organ

, photoreceptor cell R7

" adult stage " photoreceptor cell R1..6

{ 0 ninaE- } , photoreceptor cell R1--6

, photoreceptor cell R7 | presumptive

" "viable,fertile" FBgn0051200 CG31200 - http://flybase.org/reports/FBgn0051200 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254 - "SPH169, CG17837, CG31200" "IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan" CG31200 27-Aug-18 DroID_v2018_08 - - - - - Hsap\PAMR1 viable FBgn0261816 CG42758 - http://flybase.org/reports/FBgn0261816 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42758, CG13479" - CG42758 27-Aug-18 DroID_v2018_08 - - - - - Hsap\KRTAP9-6 FBgn0023062 l(1)2Dk lethal (1) 2Dk http://flybase.org/reports/FBgn0023062 - gene - - - "1200B2, l(1)2Dk" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0002185 l(3)62Bi lethal (3) 62Bi http://flybase.org/reports/FBgn0002185 - gene - - - "dre6, rbd, l(3)dre6, l(3)62Bi" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of P-stage,recessive,heat sensitive,some die during pharate adult stage" FBgn0261436 DhpD Dihydropterin deaminase http://flybase.org/reports/FBgn0261436 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR014311 dihydropterin deaminase activity ; GO:0004153 | inferred from direct assay guanine deaminase activity ; GO:0008892 | inferred from direct assay guanine catabolic process ; GO:0006147 | inferred from electronic annotation with InterPro:IPR014311 dihydropteridine metabolic process ; GO:0051067 | inferred from mutant phenotype guanine metabolic process ; GO:0046098 | inferred from mutant phenotype dihydropteridine metabolic process ; GO:0051067 | inferred from direct assay eye pigment biosynthetic process ; GO:0006726 | inferred from mutant phenotype - "DhpD, CG18143" "IPR006680:Amidohydrolase-related, IPR014311:Guanine deaminase, IPR011059:Metal-dependent hydrolase, composite domain, IPR032466:Metal-dependent hydrolase" CG18143 27-Aug-18 DroID_v2018_08 Drer\gda Scer\GUD1 Cele\cpin-1 Xtro\gda Mmus\Gda Hsap\GDA eye color defective pigment cell FBgn0046648 anon-38D.18 anon-38D.18 http://flybase.org/reports/FBgn0046648 gene - - - "38D.18, anon-38D.18" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265156 lncRNA:CR44225 - http://flybase.org/reports/FBgn0265156 non_protein_coding_gene - - - CR44225 - CR44225 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065374 l(2)SH1685 lethal (2) SH1685 http://flybase.org/reports/FBgn0065374 gene - - - "l(2)SH1685, l(2)SH2 1685" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0265740 lncRNA:CR44547 - http://flybase.org/reports/FBgn0265740 non_protein_coding_gene - - - "CR44547, lincRNA.502" - CR44547 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266949 lncRNA:CR45400 - http://flybase.org/reports/FBgn0266949 non_protein_coding_gene - - - CR45400 - CR45400 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0010896 l(3)06658 lethal (3) 06658 http://flybase.org/reports/FBgn0010896 - gene - - - l(3)06658 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0030984 tgy twiggy http://flybase.org/reports/FBgn0030984 protein_coding_gene glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity ; GO:0016263 | inferred from biological aspect of ancestor with PANTHER:PTN000547277 "O-glycan processing, core 1 ; GO:0016267 | inferred from biological aspect of ancestor with PANTHER:PTN000547277" membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR003378 "CG7440, tgy, dC1GalT5, Tgy" IPR003378:Fringe-like CG7440 27-Aug-18 DroID_v2018_08 "Drer\LOC564281, Drer\si:dkey-202e17.1, Drer\c1galt1a, Drer\c1galt1c1, Drer\c1galt1b" - "Cele\C38H2.2, Cele\bus-4, Cele\T09E11.12, Cele\W09D10.5, Cele\Y38C1AB.5, Cele\F37A4.3, Cele\E03H4.3, Cele\F56H6.1, Cele\C17A2.3, Cele\C02H6.1, Cele\Y38C1AB.1, Cele\C16D9.6" "Xtro\LOC100496837, Xtro\c1galt1" "Mmus\C1galt1c1, Mmus\C1galt1" "Hsap\C1GALT1, Hsap\C1GALT1C1" viable FBgn0005651 Mst59Da Male-specific transcript 59Da http://flybase.org/reports/FBgn0005651 - gene - - - Mst59Da - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0043996 Su(rst)D121 Su(rst)D121 http://flybase.org/reports/FBgn0043996 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "D121, Su(rst)D121" - - 27-Aug-18 DroID_v2018_08 - - - - - - viable eye FBgn0070041 3R-35-29 3R-35-29 http://flybase.org/reports/FBgn0070041 gene molecular_function ; GO:0003674 | no biological data available segment specification ; GO:0007379 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available 3R-35-29 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,germline clone,maternal effect,recessive,some die during embryonic stage" "embryonic head,germline clone,maternal effect,embryonic segment" FBgn0000773 fs(1)A1187 female sterile (1) A1187 http://flybase.org/reports/FBgn0000773 - gene - - - "fs(1)1187, fs(1)A1187" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,non-rescuable maternal effect,heat sensitive,female sterile,recessive,mitotic cell cycle defective" blastoderm embryo FBgn0005300 mei-O81 meiotic from Ostiense 81 http://flybase.org/reports/FBgn0005300 - gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mei-O81 - - 27-Aug-18 DroID_v2018_08 - - - - - - "meiotic cell cycle defective,male,recessive" spermatocyte & nuclear chromosome FBgn0043992 Su(rst)D49 Su(rst)D49 http://flybase.org/reports/FBgn0043992 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "D49, Su(rst)D49" - - 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0028550 Atf3 Activating transcription factor 3 http://flybase.org/reports/FBgn0028550 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR000837, InterPro:IPR004827 protein dimerization activity ; GO:0046983 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with Jra sequence-specific DNA binding ; GO:0043565 | inferred from direct assay" regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from electronic annotation with InterPro:IPR000837 regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype lipid homeostasis ; GO:0055088 | inferred from mutant phenotype nervous system development ; GO:0007399 | inferred from mutant phenotype immune response ; GO:0006955 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay "EG:33C11.1, CG11405, dATF3, ATF3, Atf3, atf3, A3-3, DM11" "IPR000837:AP-1 transcription factor, IPR004827:Basic-leucine zipper domain" CG11405 27-Aug-18 DroID_v2018_08 "Drer\creb5b, Drer\atf2, Drer\fosb, Drer\jdp2a, Drer\fosl2, Drer\atf7b, Drer\batf3, Drer\atf7a, Drer\atf3, Drer\si:ch211-59d15.4, Drer\si:ch211-153j24.3, Drer\jdp2b, Drer\fosl1b, Drer\fosab, Drer\fosaa, Drer\fosl1a, Drer\batf" "Scer\CST6, Scer\ACA1" "Cele\zip-11, Cele\fos-1" "Xtro\creb5, Xtro\atf7, Xtro\atf3, Xtro\atf2, Xtro\fosl1, Xtro\batf, Xtro\fosl2, Xtro\fosb, Xtro\fos" "Mmus\Fosl2, Mmus\Fosb, Mmus\Atf7, Mmus\Batf, Mmus\Atf3, Mmus\Jdp2, Mmus\Fosl1, Mmus\Batf3, Mmus\Batf2, Mmus\Creb5, Mmus\Atf2, Mmus\Fos" "Hsap\JDP2, Hsap\BATF, Hsap\FOSB, Hsap\ATF2, Hsap\FOSL1, Hsap\BATF3, Hsap\ATF3, Hsap\FOSL2, Hsap\FOS, Hsap\BATF2, Hsap\CREB5, Hsap\ATF7" "visible,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of pupal stage,some die during pupal stage,somatic clone,lethal,developmental rate defective,lethal - all die before end of larval stage,some die during larval stage,female fertile,reduced,partially,recessive" "eye,adult cuticle,dorsal,adult abdomen,somatic clone,embryonic/larval fat body,lipid particle" FBgn0058464 CR40464 - http://flybase.org/reports/FBgn0058464 non_protein_coding_gene - - - CR40464 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0044459 EP3373 EP3373 http://flybase.org/reports/FBgn0044459 gene - - - EP3373 - - 27-Aug-18 DroID_v2018_08 - - - - - - neuroanatomy defective "intersegmental nerve,anterior fascicle & synapse | supernumerary" FBgn0052546 tRNA:Pro-CGG-2-1 transfer RNA:Proline-CGG 2-1 http://flybase.org/reports/FBgn0052546 tRNA_gene CCG codon-amino acid adaptor activity ; GO:0033424 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033424 cytosol ; GO:0005829 | inferred by curator from GO:0033424 "AE002593.trna10-ProCGG, tRNA:P:CGG:AE002593, CR32546, chrX.trna14-ProCGG, tRNA-Pro-CGG-2-1, tRNA:Pro-CGG-2-1, tRNA:CR32546, CCG" - CR32546 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260125 2L3574 - http://flybase.org/reports/FBgn0260125 gene - - - 2L3574 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030678 CG11679 - http://flybase.org/reports/FBgn0030678 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG11679 IPR003734:Domain of unknown function DUF155 CG11679 27-Aug-18 DroID_v2018_08 Drer\rmnd1 "Scer\RMD8, Scer\MRX10, Scer\RMD1" Cele\ZK1010.2 Xtro\rmnd1 Mmus\Rmnd1 Hsap\RMND1 "viable,body color defective" mesothoracic tergum FBgn0065253 l(2)SH2113 lethal (2) SH2113 http://flybase.org/reports/FBgn0065253 gene - - - "l(2)SH2113, l(2)SH2 2113" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0020556 lncRNA:bxd bithoraxoid http://flybase.org/reports/FBgn0020556 "FBgn0051273, FBgn0051277" non_protein_coding_gene - "negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from expression pattern" nucleus ; GO:0005634 | inferred from direct assay "CR31277, CR31273, bxd" - CR31273 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0015880 anon-48Ai anon-48Ai http://flybase.org/reports/FBgn0015880 - gene - - - "XI, anon-48Ai" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005541 l(3)72Di lethal (3) 72Di http://flybase.org/reports/FBgn0005541 - gene - - - l(3)72Di - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal organism FBgn0259602 B0911 - http://flybase.org/reports/FBgn0259602 gene - - - B0911 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing vein L3,anterior crossvein,antennal segment,arista,tarsal segment,unguis" FBgn0023111 anon-10Aw anon-10Aw http://flybase.org/reports/FBgn0023111 - gene - - - "16, anon-10Aw" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267052 CR45496 - http://flybase.org/reports/FBgn0267052 pseudogene_attribute - - - CR45496 - CR45496 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0053263 CG33263 - http://flybase.org/reports/FBgn0053263 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "CG14106, CG33263" IPR002557:Chitin binding domain CG33263 27-Aug-18 DroID_v2018_08 - - "Cele\cbd-1, Cele\W03F11.1" - - - FBgn0262959 T:SS-Lcp2 Signal sequence of Lcp2 http://flybase.org/reports/FBgn0262959 engineered_tag - - - "T:SS-Lcp2, T:Lcp2" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035035 Samtor - http://flybase.org/reports/FBgn0035035 protein_coding_gene rRNA (adenine) methyltransferase activity ; GO:0016433 | inferred from biological aspect of ancestor with PANTHER:PTN001842290 - nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN001842290 CG3570 "IPR029063:S-adenosyl-L-methionine-dependent methyltransferase, IPR021867:25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2" CG3570 27-Aug-18 DroID_v2018_08 Drer\zgc:153606 - - Xtro\c7orf60 Mmus\Bmt2 Hsap\BMT2 viable FBgn0267741 CR46072 - http://flybase.org/reports/FBgn0267741 pseudogene_attribute - - - CR46072 - CR46072 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000469 dlmd dorsal longitudinal muscle-defective http://flybase.org/reports/FBgn0000469 - gene - - - dlmd - - 27-Aug-18 DroID_v2018_08 - - - - - - "flight defective,dominant" FBgn0085737 CR40502 - http://flybase.org/reports/FBgn0085737 rRNA_gene - - - CR40502 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0082183 l(4)CB-6471-3 lethal (4) CB-6471-3 http://flybase.org/reports/FBgn0082183 gene - - - l(4)CB-6471-3 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0001413 l(1)3Ec lethal (1) 3Ec http://flybase.org/reports/FBgn0001413 - gene - - - l(1)3Ec - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0039942 CG17163 - http://flybase.org/reports/FBgn0039942 protein_coding_gene - - - CG17163 - CG17163 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0011607 l(1)I33h29 lethal (1) I33h29 http://flybase.org/reports/FBgn0011607 FBgn0010206 gene - - - "l(1)I33b29, l(1)33h29, l(1)I33h29" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0069338 UY2129 UY2129 http://flybase.org/reports/FBgn0069338 gene - - - UY2129 - - 27-Aug-18 DroID_v2018_08 - - - - - - neuroanatomy defective "mushroom body & axon7B,Kenyon cell" FBgn0019968 Khc-73 Kinesin heavy chain 73 http://flybase.org/reports/FBgn0019968 FBgn0025191 protein_coding_gene "microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR001752 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001752, InterPro:IPR019821 microtubule motor activity ; GO:0003777 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 protein homodimerization activity ; GO:0042803 | inferred from direct assay microtubule motor activity ; GO:0003777 | inferred from direct assay microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity ATPase activity ; GO:0016887 | inferred from biological aspect of ancestor with PANTHER:PTN000648413" plus-end-directed vesicle transport along microtubule ; GO:0072383 | inferred from electronic annotation with InterPro:IPR032923 microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity cytoskeleton-dependent intracellular transport ; GO:0030705 | inferred from biological aspect of ancestor with PANTHER:PTN000648522 regulation of synapse structure or activity ; GO:0050803 | inferred from mutant phenotype microtubule-based movement ; GO:0007018 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 establishment of spindle orientation ; GO:0051294 | inferred from mutant phenotype microtubule plus-end ; GO:0035371 | inferred from direct assay early endosome ; GO:0005769 | inferred from direct assay kinesin complex ; GO:0005871 | inferred from sequence or structural similarity kinesin complex ; GO:0005871 | inferred from biological aspect of ancestor with PANTHER:PTN000648413 astral microtubule ; GO:0000235 | colocalizes_with inferred from direct assay "CG8183, DmKlp73, DmKIN73, anon-EST:fe3C9, Khc-73, KLP73, Kinesin-73, Khc73, khc-73, DmKin73, Kin73, KIF 13A, KHC-73, KIF13A/B" "IPR000253:Forkhead-associated (FHA) domain, IPR000938:CAP Gly-rich domain, IPR001752:Kinesin motor domain, IPR008984:SMAD/FHA domain, IPR019821:Kinesin motor domain, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR000008:C2 domain, IPR022140:Kinesin-like KIF1-type, IPR022164:Kinesin-like, IPR032405:Kinesin-associated, IPR032923:Kinesin-like protein KIF13" CG8183 27-Aug-18 DroID_v2018_08 "Drer\kif1aa, Drer\kif16ba, Drer\kif16bb, Drer\kif13a, Drer\stard9, Drer\kif14, Drer\si:rp71-84d9.2, Drer\kif1ab, Drer\kif1c, Drer\kif13bb, Drer\kif1b, Drer\kif13ba" "Scer\KIP2, Scer\KIP1, Scer\CIN8" "Cele\klp-4, Cele\klp-6, Cele\unc-104" "Xtro\kif1c, Xtro\kif16b, Xtro\kif14, Xtro\kif1b, Xtro\kif13b, Xtro\kif1a" "Mmus\Gm1305, Mmus\Kif13b, Mmus\Kif1c, Mmus\Stard9, Mmus\Kif13a, Mmus\Kif16b, Mmus\Kif14, Mmus\Kif1a, Mmus\Kif1b" "Hsap\KIF16B, Hsap\STARD9, Hsap\KIF13A, Hsap\KIF1A, Hsap\KIF1C, Hsap\KIF1B, Hsap\KIF13B, Hsap\KIF14" neurophysiology defective t-bar FBgn0266087 lncRNA:CR44829 - http://flybase.org/reports/FBgn0266087 non_protein_coding_gene - - - CR44829 - CR44829 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036423 CG3919 - http://flybase.org/reports/FBgn0036423 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR004210 - - CG3919 "IPR004210:BESS motif, IPR006578:MADF domain" CG3919 27-Aug-18 DroID_v2018_08 "Drer\LOC100330838, Drer\zgc:152938, Drer\si:ch211-207i20.3" - "Cele\madf-10, Cele\madf-4, Cele\madf-9, Cele\madf-5, Cele\madf-8, Cele\madf-2, Cele\madf-3" - - - viable FBgn0286051 Rexo5 - http://flybase.org/reports/FBgn0035707 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR012337 - - CG8368 "IPR012337:Ribonuclease H-like domain, IPR013520:Exonuclease, RNase T/DNA polymerase III" CG8368 27-Aug-18 DroID_v2018_08 "Drer\zgc:152968, Drer\rexo1, Drer\rexo4, Drer\isg20" "Scer\REX3, Scer\RNH70" Cele\C05C8.5 "Xtro\rexo4, Xtro\LOC100036702, Xtro\rexo1, Xtro\LOC100158551" "Mmus\Rexo1, Mmus\Rexo4, Mmus\Isg20, Mmus\2610020H08Rik" "Hsap\LOC81691, Hsap\LOC101929627, Hsap\REXO4, Hsap\ISG20, Hsap\REXO1" viable FBgn0039915 Gat GABA transporter http://flybase.org/reports/FBgn0039915 protein_coding_gene neurotransmitter:sodium symporter activity ; GO:0005328 | inferred from electronic annotation with InterPro:IPR000175 gamma-aminobutyric acid:sodium symporter activity ; GO:0005332 | inferred from sequence model gamma-aminobutyric acid:sodium symporter activity ; GO:0005332 | inferred from biological aspect of ancestor with PANTHER:PTN000177868 neurotransmitter transport ; GO:0006836 | inferred from electronic annotation with InterPro:IPR000175 chemical synaptic transmission ; GO:0007268 | inferred from biological aspect of ancestor with PANTHER:PTN000177868 cellular response to mechanical stimulus ; GO:0071260 | inferred from direct assay gamma-aminobutyric acid transport ; GO:0015812 | inferred from biological aspect of ancestor with PANTHER:PTN000177868 gamma-aminobutyric acid import ; GO:0051939 | inferred from sequence model plasma membrane ; GO:0005886 | inferred from direct assay glial cell projection ; GO:0097386 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 integral component of membrane ; GO:0016021 | inferred from sequence model neuron projection ; GO:0043005 | inferred from biological aspect of ancestor with PANTHER:PTN000177868 "anon-WO0149848.11, CG1732, CG1732a, DmGAT, CG6218, dGAT, GAT, Gat, gat" IPR000175:Sodium:neurotransmitter symporter CG1732 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-132b12.3, Drer\slc6a1a, Drer\slc6a16b, Drer\slc6a11a, Drer\slc6a19a.2, Drer\slc6a13l, Drer\si:ch211-132b12.6, Drer\slc6a16a, Drer\si:ch211-132b12.2, Drer\slc6a14, Drer\slc6a15, Drer\slc6a4a, Drer\si:ch211-117c9.5, Drer\slc6a4b, Drer\slc6a1b, Drer\slc6a13, Drer\si:ch211-132b12.1, Drer\slc6a5, Drer\zgc:158427, Drer\slc6a13, Drer\slc6a19a.1, Drer\slc6a19b, Drer\slc6a6a, Drer\zgc:158225, Drer\slc6a17, Drer\slc6a8, Drer\slc6a2, Drer\slc6a18, Drer\slc6a9, Drer\slc6a1l, Drer\slc6a6b, Drer\zgc:174946" - "Cele\snf-11, Cele\snf-9, Cele\snf-3, Cele\mod-5, Cele\dat-1, Cele\snf-6" "Xtro\slc6a13, Xtro\slc6a5, Xtro\slc6a15, Xtro\slc6a14.2, Xtro\slc6a3, Xtro\slc6a17, Xtro\slc6a19, Xtro\slc6a2, Xtro\slc6a6, Xtro\slc6a4, Xtro\slc6a12, Xtro\slc6a9, Xtro\slc6a8, Xtro\slc6a7, Xtro\slc6a16, Xtro\LOC100127682, Xtro\slc6a1" "Mmus\Slc6a20b, Mmus\Slc6a12, Mmus\Slc6a2, Mmus\Slc6a3, Mmus\Slc6a15, Mmus\Slc6a20a, Mmus\Slc6a16, Mmus\Slc6a17, Mmus\Slc6a11, Mmus\Slc6a14, Mmus\Slc6a19, Mmus\Slc6a8, Mmus\Slc6a5, Mmus\Slc6a9, Mmus\Slc6a18, Mmus\Slc6a4, Mmus\Slc6a7, Mmus\Slc6a6, Mmus\Slc6a21, Mmus\Slc6a1, Mmus\Slc6a13" "Hsap\SLC6A16, Hsap\SLC6A4, Hsap\SLC6A13, Hsap\SLC6A2, Hsap\SLC6A18, Hsap\SLC6A5, Hsap\SLC6A15, Hsap\SLC6A3, Hsap\SLC6A19, Hsap\SLC6A9, Hsap\SLC6A7, Hsap\SLC6A8, Hsap\SLC6A11, Hsap\SLC6A1, Hsap\SLC6A14, Hsap\SLC6A6, Hsap\SLC6A20, Hsap\SLC6A17, Hsap\SLC6A12" viable FBgn0262104 CG42857 - http://flybase.org/reports/FBgn0262104 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42857, DMG6-MB6.chr3R.10.010" - CG42857 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0053740 snmRNA:430n snmRNA:430:CR33740 http://flybase.org/reports/FBgn0053740 non_protein_coding_gene - - - "CR33740, snmRNA:430:CR33740" - CR33740 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0053977 CG33977 - http://flybase.org/reports/FBgn0053977 protein_coding_gene dolichyl-phosphate beta-D-mannosyltransferase activity ; GO:0004582 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000419487 protein O-linked mannosylation ; GO:0035269 | inferred from biological aspect of ancestor with PANTHER:PTN000419487 GPI anchor biosynthetic process ; GO:0006506 | inferred from biological aspect of ancestor with PANTHER:PTN000419487 GPI anchor biosynthetic process ; GO:0006506 | inferred from sequence or structural similarity with HGNC:3007 endoplasmic reticulum membrane ; GO:0005789 | inferred from biological aspect of ancestor with PANTHER:PTN000419487 endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with HGNC:3007 dolichol-phosphate-mannose synthase complex ; GO:0033185 | inferred from biological aspect of ancestor with PANTHER:PTN000419487 CG33977 IPR013174:Dolichol-phosphate mannosyltransferase subunit 3 CG33977 27-Aug-18 DroID_v2018_08 Drer\dpm3 - "Cele\F49E11.8, Cele\fbxa-76, Cele\C24H12.1, Cele\T27A1.3, Cele\dpm-3" Xtro\dpm3 Mmus\Dpm3 Hsap\DPM3 FBgn0053777 CG33777 - http://flybase.org/reports/FBgn0053777 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33777 IPR010512:Protein of unknown function DUF1091 CG33777 27-Aug-18 DroID_v2018_08 - - Cele\K12H4.7 - - - FBgn0085774 CR40779 - http://flybase.org/reports/FBgn0085774 rRNA_gene - - - CR40779 - CR40779 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0063508 En(tc) Enhancer of terminal conversion http://flybase.org/reports/FBgn0063508 gene - - - En(tc) - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262064 EG165 - http://flybase.org/reports/FBgn0262064 gene - - - EG165 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0065813 l(2)SH0382 lethal (2) SH0382 http://flybase.org/reports/FBgn0065813 gene - - - "l(2)SH0382, l(2)SH2 0382" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0261258 rgn regeneration http://flybase.org/reports/FBgn0261258 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from sequence or structural similarity with Lectin-galC1 tissue regeneration ; GO:0042246 | inferred from expression pattern inferred from mutant phenotype - "l(3)00534, rgn, CG6014, BcDNA:GH11973" "IPR001304:C-type lectin-like, IPR016186:C-type lectin-like/link domain, IPR016187:C-type lectin fold" CG6014 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-28d5.8, Drer\si:ch211-170d8.8, Drer\si:dkey-88n24.9, Drer\si:dkey-81n2.1, Drer\lca5, Drer\si:dkey-28d5.14, Drer\si:dkey-88n24.10, Drer\si:dkey-28d5.13, Drer\si:ch211-282j17.3, Drer\si:dkey-241l7.3, Drer\LOC100000851, Drer\si:ch211-225k7.6, Drer\si:dkey-83f18.10, Drer\si:dkey-83f18.7, Drer\si:ch211-282j17.7, Drer\si:dkey-81n2.2, Drer\si:ch211-272h9.3, Drer\si:ch211-225k7.4, Drer\LOC101882781, Drer\si:dkey-28d5.10, Drer\si:dkey-28d5.12, Drer\si:ch211-63p21.4, Drer\si:ch211-225k7.2, Drer\si:dkey-83f18.3, Drer\si:dkey-88n24.7, Drer\si:dkey-192d15.3, Drer\si:dkey-83f18.9, Drer\si:dkey-241l7.5, Drer\si:dkey-88n24.6, Drer\si:ch73-335d12.2, Drer\si:ch211-193e13.5, Drer\zgc:194252, Drer\si:dkey-28d5.4, Drer\si:ch211-225k7.5, Drer\si:dkey-241l7.6, Drer\si:ch211-282j17.8, Drer\mns1, Drer\si:dkey-83f18.11, Drer\zgc:162060, Drer\si:dkey-26c10.5, Drer\si:ch211-282j17.11, Drer\si:dkey-28d5.9, Drer\si:ch211-282j17.10, Drer\si:dkey-88n24.8, Drer\si:ch211-282j17.1, Drer\si:dkey-83f18.5" - "Cele\clec-52, Cele\clec-22, Cele\clec-24, Cele\clec-53, Cele\clec-196, Cele\clec-25, Cele\clec-146, Cele\clec-51" Xtro\LOC100170489 "Mmus\Klrg1, Mmus\Clec2h, Mmus\Clec12a, Mmus\Klrb1f, Mmus\Klrb1a, Mmus\Reg3g, Mmus\Clec2f, Mmus\Clec7a, Mmus\Klra8, Mmus\Klrb1c, Mmus\Klrg2, Mmus\Clec2d, Mmus\Klra6, Mmus\Reg3d, Mmus\Klra17, Mmus\Clec2j, Mmus\Klrc2, Mmus\Reg4, Mmus\Klri1, Mmus\Klrb1b, Mmus\Clec2l, Mmus\Clec9a, Mmus\Clec1a, Mmus\Reg1, Mmus\Clec2e, Mmus\Klrd1, Mmus\Olr1, Mmus\4922502D21Rik, Mmus\Clec12b, Mmus\Cd69, Mmus\Klra7, Mmus\Reg2, Mmus\Klrc3, Mmus\Klra2, Mmus\Klrb1, Mmus\Klre1, Mmus\Clec5a, Mmus\Klrc1, Mmus\Klra3, Mmus\Klra4, Mmus\Clec2g, Mmus\Klra10, Mmus\Klra9, Mmus\Clec2i, Mmus\Klri2, Mmus\Klra1, Mmus\Gm156, Mmus\Klra5, Mmus\Clec1b, Mmus\Reg3b, Mmus\Klrk1" "Hsap\KLRF1, Hsap\REG3A, Hsap\CLEC9A, Hsap\KLRC1, Hsap\REG1B, Hsap\FCER2, Hsap\CD69, Hsap\REG4, Hsap\CLECL1, Hsap\CLEC1B, Hsap\MRC2, Hsap\COLEC12, Hsap\MRC1, Hsap\KLRF2, Hsap\KLRC4-KLRK1, Hsap\CLEC2L, Hsap\CLEC2D, Hsap\CLEC12B, Hsap\BCAN, Hsap\KLRC3, Hsap\KLRG2, Hsap\KLRD1, Hsap\OLR1, Hsap\CLEC1A, Hsap\CLEC2A, Hsap\KLRB1, Hsap\REG1A, Hsap\NCAN, Hsap\KLRK1, Hsap\KLRC4, Hsap\REG3G, Hsap\CLEC2B, Hsap\KLRG1, Hsap\CLEC12A, Hsap\CLEC5A, Hsap\CLEC7A, Hsap\KLRC2" FBgn0025383 CG14780 - http://flybase.org/reports/FBgn0025383 - protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP95, EG:80H7.3, CG14780" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG14780 27-Aug-18 DroID_v2018_08 "Drer\gzmk, Drer\LOC100004427, Drer\zgc:165423, Drer\zgc:92313, Drer\si:dkeyp-93a5.3, Drer\si:dkey-16l2.17, Drer\gzma, Drer\cfd, Drer\zgc:163079, Drer\si:ch211-165b19.5, Drer\si:ch211-165b19.8, Drer\ovch1, Drer\gzm3, Drer\si:ch211-165b19.9" - "Cele\try-6, Cele\try-1" - "Mmus\Prss2, Mmus\Klk15, Mmus\Klk9" "Hsap\KLK15, Hsap\KLK9" viable FBgn0037610 CG8043 - http://flybase.org/reports/FBgn0037610 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:27302 iron-sulfur cluster assembly ; GO:0016226 | inferred from biological aspect of ancestor with PANTHER:PTN000503456 iron-sulfur cluster assembly ; GO:0016226 | inferred from sequence or structural similarity with SGD:S000003883 mitochondrial matrix ; GO:0005759 | inferred from biological aspect of ancestor with PANTHER:PTN000503457 mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with SGD:S000003883 "CG8043, Iba57" "IPR006222:Glycine cleavage T-protein-like, N-terminal, IPR013977:Glycine cleavage T-protein, C-terminal barrel domain, IPR017703:YgfZ/GcvT conserved site" CG8043 27-Aug-18 DroID_v2018_08 Drer\iba57 Scer\IBA57 Cele\F39H2.3 Xtro\iba57 Mmus\Iba57 Hsap\IBA57 "partially lethal - majority die,some die during pupal stage,locomotor rhythm defective" FBgn0033279 CG2291 - http://flybase.org/reports/FBgn0033279 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT16234, CG2291" - CG2291 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0015359 CG2034 - http://flybase.org/reports/FBgn0015359 - protein_coding_gene - - Elongator holoenzyme complex ; GO:0033588 | inferred from electronic annotation with InterPro:IPR019519 "anon-i1, CG2034" IPR019519:Elongator complex protein 5 CG2034 27-Aug-18 DroID_v2018_08 Drer\elp5 - - - Mmus\Elp5 Hsap\ELP5 viable embryonic/larval hemocyte | third instar larval stage FBgn0052305 CG32305 - http://flybase.org/reports/FBgn0052305 protein_coding_gene guanylate cyclase activity ; GO:0004383 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 "intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR001054, InterPro:IPR018297 signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 cGMP biosynthetic process ; GO:0006182 | inferred from biological aspect of ancestor with PANTHER:PTN000229249" "guanylate cyclase complex, soluble ; GO:0008074 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000228924" "CG8970, AC, CG32305" "IPR001054:Adenylyl cyclase class-3/4/guanylyl cyclase, IPR018297:Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR029787:Nucleotide cyclase" CG32305 27-Aug-18 DroID_v2018_08 "Drer\adcy1a, Drer\adcy7, Drer\adcy5, Drer\adcy6b, Drer\adcy6a, Drer\adcy2a, Drer\adcy1b, Drer\adcy8, Drer\adcy2b, Drer\adcy3a, Drer\si:ch211-132f19.7, Drer\si:dkey-206f10.1" - "Cele\acy-4, Cele\acy-2" "Xtro\dnajc27, Xtro\adcy4, Xtro\adcy7, Xtro\adcy6, Xtro\adcy1" "Mmus\Adcy7, Mmus\Adcy6, Mmus\Adcy8, Mmus\Adcy4, Mmus\Adcy1, Mmus\Adcy2, Mmus\Adcy5, Mmus\Adcy3" "Hsap\ADCY3, Hsap\ADCY5, Hsap\ADCY6, Hsap\ADCY4, Hsap\ADCY7, Hsap\ADCY8, Hsap\ADCY1, Hsap\ADCY2" viable FBgn0002188 l(3)63Aa lethal (3) 63Aa http://flybase.org/reports/FBgn0002188 - gene - - - l(3)63Aa - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0030035 PIG-T Phosphatidylinositol glycan anchor biosynthesis class T http://flybase.org/reports/FBgn0030035 protein_coding_gene GPI-anchor transamidase activity ; GO:0003923 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000311103 attachment of GPI anchor to protein ; GO:0016255 | inferred from sequence or structural similarity with protein_id:BAB60854.1 attachment of GPI anchor to protein ; GO:0016255 | inferred from biological aspect of ancestor with PANTHER:PTN000311103 GPI-anchor transamidase complex ; GO:0042765 | inferred from biological aspect of ancestor with PANTHER:PTN000311103 endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with protein_id:BAB60854.1 "Dm*AAF46367/27-522, CG11190, PIG-T" IPR007245:GPI transamidase component PIG-T CG11190 27-Aug-18 DroID_v2018_08 Drer\pigt Scer\GPI16 Cele\F17C11.7 Xtro\pigt Mmus\Pigt Hsap\PIGT "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0015771 N::tor N::tor http://flybase.org/reports/FBgn0015771 - engineered_fusion_gene - - - N::tor - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "microchaeta,precursor,wing disc" FBgn0030457 CG12096 - http://flybase.org/reports/FBgn0030457 protein_coding_gene - proteasome regulatory particle assembly ; GO:0070682 | inferred from biological aspect of ancestor with PANTHER:PTN000339132 cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype "proteasome regulatory particle, base subcomplex ; GO:0008540 | inferred from biological aspect of ancestor with PANTHER:PTN000339132" "CG12096, 12096, S5b/PSMD5, dS5b, S5b" "IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical, IPR019538:26S proteasome non-ATPase regulatory subunit 5" CG12096 27-Aug-18 DroID_v2018_08 Drer\psmd5 - Cele\F35G12.12 Xtro\psmd5 Mmus\Psmd5 Hsap\PSMD5 "viable,fertile" FBgn0262455 mir-1 mir-1 stem loop http://flybase.org/reports/FBgn0262455 miRNA_gene - "cardiocyte differentiation ; GO:0035051 | inferred from mutant phenotype regulation of Notch signaling pathway ; GO:0008593 | inferred from mutant phenotype gene silencing by miRNA ; GO:0035195 | inferred from direct assay positive regulation of nuclear-transcribed mRNA poly(A) tail shortening ; GO:0060213 | inferred from genetic interaction with Ge-1, me31B muscle cell cellular homeostasis ; GO:0046716 | inferred from mutant phenotype" - "miR-1, mir-1, dme-mir-1, MIR-1, CR43027, dmiR-1, DmiR-1, Mir-1, CR32958, transfrag 8, Mir1, mirR-1, MiR-1, miR1, dme-miR-1-3p, dme-miR-1" - CR43027 27-Aug-18 DroID_v2018_08 - - - - - - embryonic stage -- adult stage FBgn0022983 rdgB::Rnor\Pitpna rdgB::Rnor\PITPNA http://flybase.org/reports/FBgn0022983 - engineered_fusion_gene - - - "rdgB::Rat\PITPNA, rdgB::Rnor\PITPNA" - - 27-Aug-18 DroID_v2018_08 - - - - - - "rhabdomere R5,rhabdomere R6,retina,rhabdomere R1,rhabdomere R2,rhabdomere R3,rhabdomere R4" FBgn0085616 CG41326 - http://flybase.org/reports/FBgn0085616 protein_coding_gene - - - CG41326 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004128 l(2)43Cb lethal (2) 43Cb http://flybase.org/reports/FBgn0004128 FBgn0014246 gene - - - "43Cb, l(2)43Cb" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0052163 CG32163 - http://flybase.org/reports/FBgn0052163 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG32163 "IPR016181:Acyl-CoA N-acyltransferase, IPR031165:Yjdj-type Gcn5-related N-acetyltransferase" CG32163 27-Aug-18 DroID_v2018_08 "Drer\im:6904045, Drer\natd1" - Cele\ZK1098.11 Xtro\natd1 Mmus\Natd1 Hsap\NATD1 viable DRSC21888 EK -1.004865896 0.362191192 3.828094224 0.167604634 -0.16325746 -1.502401665 FBgn0042198 CG16741 - http://flybase.org/reports/FBgn0042198 protein_coding_gene - - - "CG18463, CG16741" - CG16741 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0263210 CR43380 - http://flybase.org/reports/FBgn0263210 pseudogene_attribute - - - CR43380 - CR43380 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0041118 l(2)k077 lethal (2) k077 http://flybase.org/reports/FBgn0041118 gene - - - l(2)k077 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0022291 l(2)04518b lethal (2) 04518b http://flybase.org/reports/FBgn0022291 - gene - - - l(2)04518b - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0267428 CG45781 - http://flybase.org/reports/FBgn0267428 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of plasma membrane ; GO:0005887 | inferred from sequence model "CG45781, CG42644, CG40378, 40378, CG43676" "IPR007110:Immunoglobulin-like domain, IPR003599:Immunoglobulin subtype, IPR013783:Immunoglobulin-like fold, IPR003598:Immunoglobulin subtype 2, IPR013098:Immunoglobulin I-set, IPR013106:Immunoglobulin V-set domain" CG45781 27-Aug-18 DroID_v2018_08 "Drer\pigrl4.2, Drer\mxra8a, Drer\zgc:153073, Drer\negr1, Drer\LOC100151468, Drer\igsf11, Drer\cxadr, Drer\si:zfos-1011f11.1, Drer\opcml, Drer\vsig8a, Drer\si:ch211-9d9.7, Drer\esamb, Drer\jam2b, Drer\mxra8b, Drer\vsig8b, Drer\jam3b, Drer\si:ch211-215e19.3, Drer\f11r.2, Drer\ntm, Drer\si:dkey-65b12.12, Drer\jam2a, Drer\jam3a, Drer\zgc:110372, Drer\cxcr3.1, Drer\lsamp, Drer\si:dkey-250k15.10, Drer\f11r.1, Drer\gpa33, Drer\esama" - Cele\rig-5 "Xtro\ntm, Xtro\negr1, Xtro\lsamp" "Mmus\Cxadr, Mmus\Jam3, Mmus\Igsf11, Mmus\Esam, Mmus\Mxra8, Mmus\Hepacam2, Mmus\F11r, Mmus\Vsig1, Mmus\Jam2, Mmus\Lsamp, Mmus\Gm1123, Mmus\Negr1, Mmus\Clmp, Mmus\Iglon5, Mmus\Ntm, Mmus\Gpa33, Mmus\Vsig2, Mmus\Vsig8, Mmus\Opcml, Mmus\Vsir, Mmus\Igsf5" "Hsap\VSIG8, Hsap\IGSF11, Hsap\MXRA8, Hsap\ESAM, Hsap\F11R, Hsap\LSAMP, Hsap\CLMP, Hsap\VSIG1, Hsap\OPCML, Hsap\CXADR, Hsap\GPA33, Hsap\JAM2, Hsap\NTM, Hsap\JAM3, Hsap\IGLON5, Hsap\NEGR1, Hsap\C10orf54, Hsap\EMB, Hsap\IGSF5, Hsap\C1orf204, Hsap\VSIG2" FBgn0011948 tRNA:Arg-TCG-3-1 transfer RNA:Arginine-TCG 3-1 http://flybase.org/reports/FBgn0011948 "FBgn0011947, FBgn0052622, FBgn0060082" tRNA_gene CGA codon-amino acid adaptor activity ; GO:0033431 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033431 cytosol ; GO:0005829 | inferred by curator from GO:0033431 "tRNA-Arg, tRNA[arg], AE002593.trna4-ArgTCG, tRNA:R1, tRNA:arg1, tRNA:R:TCG:AE002593-b, CR32622, tRNA:arg12Ea, chrX.trna8-ArgTCG, tRNA-Arg-TCG-3-1, tRNA:Arg-TCG-3-1, tRNA:R:12Ea, CGA" - CR32622 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085516 CG40769 - http://flybase.org/reports/FBgn0085516 protein_coding_gene - - - CG40769 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039331 ND-49L NADH dehydrogenase (ubiquinone) 49 kDa subunit-like http://flybase.org/reports/FBgn0039331 protein_coding_gene NAD binding ; GO:0051287 | inferred from electronic annotation with InterPro:IPR001135 quinone binding ; GO:0048038 | inferred from electronic annotation with InterPro:IPR001135 NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:O95299 "mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with UniProtKB:O95299" mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:O95299 "CG111913, CG11913, Q9VBR4_DROME, NUCM, ND-49L" "IPR001135:NADH-quinone oxidoreductase, subunit D, IPR014029:NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site, IPR029014:NiFe hydrogenase-like, IPR022885:NAD(P)H-quinone oxidoreductase subunit D/H" CG11913 27-Aug-18 DroID_v2018_08 Drer\ndufs2 - "Cele\nduf-2.2, Cele\gas-1" Xtro\ndufs2 Mmus\Ndufs2 Hsap\NDUFS2 viable FBgn0051680 CG31680 - http://flybase.org/reports/FBgn0051680 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "BcDNA:AT19802, CG31680" - CG31680 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0050485 CG30485 - http://flybase.org/reports/FBgn0050485 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG13342, CG30485" - CG30485 27-Aug-18 DroID_v2018_08 - - - - Mmus\Akap11 Hsap\AKAP11 viable FBgn0028645 beat-Ib beaten path Ib http://flybase.org/reports/FBgn0028645 protein_coding_gene molecular_function ; GO:0003674 | no biological data available heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0007157 | inferred from sequence or structural similarity with beat-Ic integral component of plasma membrane ; GO:0005887 | inferred from sequence model "beat-B, beat Ib, CT23325, BG:DS00365.4, CG7644, BcDNA:RE51929, beat-Ib, Beat-Ib" "IPR007110:Immunoglobulin-like domain, IPR013783:Immunoglobulin-like fold" CG7644 27-Aug-18 DroID_v2018_08 "Drer\zgc:172106, Drer\f11r.2, Drer\jam2b" - - Xtro\f11r - Hsap\CADM2 "viable,fertile" FBgn0010295 ng3 new glue 3 http://flybase.org/reports/FBgn0010295 FBgn0063122 protein_coding_gene - - - "ng-3, ng, EG:96G10.3, CG10788, BcDNA:LP03924, ng3" - CG10788 27-Aug-18 DroID_v2018_08 - - - - - - larval stage | third instar embryonic/larval salivary gland

viable FBgn0034432 CG7461 - http://flybase.org/reports/FBgn0034432 protein_coding_gene "acyl-CoA dehydrogenase activity ; GO:0003995 | inferred from electronic annotation with InterPro:IPR006089, InterPro:IPR006091 flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR013786" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006089, InterPro:IPR006091, InterPro:IPR009075, InterPro:IPR009100, InterPro:IPR013786" microtubule associated complex ; GO:0005875 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay "CG7461, cg7461" "IPR006089:Acyl-CoA dehydrogenase, conserved site, IPR006091:Acyl-CoA oxidase/dehydrogenase, central domain, IPR009075:Acyl-CoA dehydrogenase/oxidase C-terminal, IPR009100:Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain, IPR013786:Acyl-CoA dehydrogenase/oxidase, N-terminal" CG7461 27-Aug-18 DroID_v2018_08 "Drer\acad8, Drer\acadm, Drer\acad9, Drer\acadvl, Drer\acads" - "Cele\acdh-9, Cele\acdh-7, Cele\acdh-4, Cele\acdh-1, Cele\acdh-8, Cele\acdh-12" "Xtro\acad8, Xtro\acadsb, Xtro\ivd, Xtro\MGC107841, Xtro\acad9, Xtro\acadm, Xtro\acads" "Mmus\Acadm, Mmus\Acad8, Mmus\Acadvl, Mmus\Acad9, Mmus\Acadsb, Mmus\Ivd, Mmus\Acads" "Hsap\ACADSB, Hsap\IVD, Hsap\ACADS, Hsap\ACAD9, Hsap\ACADM, Hsap\ACADVL, Hsap\ACAD8" "viable,fertile" FBgn0267353 BG02514 - http://flybase.org/reports/FBgn0267353 gene - - - BG02514 - - 27-Aug-18 DroID_v2018_08 - - - - - - "short lived,female,male,heat stress response defective,starvation stress response defective,chemosensitive behavior defective" macrochaeta FBgn0264650 littoral littoral http://flybase.org/reports/FBgn0264650 gene - trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype - littoral - - 27-Aug-18 DroID_v2018_08 - - - - - - "terminal tracheal cell,embryonic/larval tracheal system,eye,somatic clone" FBgn0052552 CG32552 - http://flybase.org/reports/FBgn0052552 protein_coding_gene - - - CG32552 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060756 l(3)S063913b lethal (3) S063913b http://flybase.org/reports/FBgn0060756 gene - - - "0639/13, l(3)S063913b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0265725 CG44532 - http://flybase.org/reports/FBgn0265725 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "lincRNA.970, CG44532" - CG44532 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0025744 maz matzerath http://flybase.org/reports/FBgn0025744 - gene - - - maz - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,visible,dominant,viable" "central nervous system,wing vein,ectopic" FBgn0030804 CG13002 - http://flybase.org/reports/FBgn0030804 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13002 "IPR006601:Uncharacterised protein family DM11, Drosophila melanogaster" CG13002 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0261634 CG42717 - http://flybase.org/reports/FBgn0261634 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 - - "CG42717, HDC10387, DMG4-MB6.chr3L.27.007, DMG4-MB6.chr3L.27.007-MIP19202" IPR002223:Pancreatic trypsin inhibitor Kunitz domain CG42717 27-Aug-18 DroID_v2018_08 - - "Cele\bli-5, Cele\C10G8.2" - "Mmus\Wfdc6a, Mmus\Eppin, Mmus\Wfdc6b" "Hsap\EPPIN-WFDC6, Hsap\EPPIN" FBgn0004943 agl angle winglike http://flybase.org/reports/FBgn0004943 - gene - - - agl - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive" wing FBgn0030968 CG7322 - http://flybase.org/reports/FBgn0030968 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR020904 - - CG7322 "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain, IPR020904:Short-chain dehydrogenase/reductase, conserved site" CG7322 27-Aug-18 DroID_v2018_08 "Drer\dcxr, Drer\zgc:101858" "Scer\AYR1, Scer\SPS19, Scer\YIR035C, Scer\IRC24" "Cele\dhs-21, Cele\T25G12.13, Cele\Y47G6A.22" "Xtro\dcxr, Xtro\MGC79752" "Mmus\Cbr2, Mmus\Dcxr" Hsap\DCXR viable FBgn0266842 lncRNA:CR45304 - http://flybase.org/reports/FBgn0266842 non_protein_coding_gene - - - CR45304 - CR45304 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037489 CG1234 - http://flybase.org/reports/FBgn0037489 protein_coding_gene chromatin binding ; GO:0003682 | inferred from biological aspect of ancestor with PANTHER:PTN000374010 - nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000374010 nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q07896 CG1234 "IPR005612:CCAAT-binding factor, IPR011501:Nucleolar complex-associated protein 3, N-terminal, IPR016024:Armadillo-type fold, IPR016903:Nucleolar complex-associated protein 3, IPR011989:Armadillo-like helical" CG1234 27-Aug-18 DroID_v2018_08 Drer\noc3l Scer\NOC3 Cele\C37H5.5 Xtro\noc3l Mmus\Noc3l Hsap\NOC3L "lethal,partially lethal - majority die,visible" mesothoracic tergum FBgn0259748 CG42397 - http://flybase.org/reports/FBgn0259748 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 CG42397 IPR002557:Chitin binding domain CG42397 27-Aug-18 DroID_v2018_08 - - "Cele\cpg-1, Cele\C39D10.7, Cele\R02F2.4, Cele\cpg-2" - - - FBgn0030099 CG12056 - http://flybase.org/reports/FBgn0030099 protein_coding_gene heme binding ; GO:0020037 | inferred from biological aspect of ancestor with PANTHER:PTN000031542 - endomembrane system ; GO:0012505 | inferred from biological aspect of ancestor with PANTHER:PTN000031541 membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN000031541 CG12056 IPR001199:Cytochrome b5-like heme/steroid binding domain CG12056 27-Aug-18 DroID_v2018_08 "Drer\cyb5d2, Drer\nenf" - Cele\tag-131 "Xtro\cyb5d2, Xtro\nenf" "Mmus\Nenf, Mmus\Cyb5d2" "Hsap\NENF, Hsap\CYB5D2" FBgn0004512 Mdr49 Multi drug resistance 49 http://flybase.org/reports/FBgn0004512 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR011527, InterPro:IPR017871 drug transmembrane transporter activity ; GO:0015238 | non-traceable author statement xenobiotic-transporting ATPase activity ; GO:0008559 | inferred from sequence or structural similarity with UniProtKB:Q00748 efflux transmembrane transporter activity ; GO:0015562 | inferred from sequence or structural similarity with UniProtKB:Q00748" transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011527 drug transmembrane transport ; GO:0006855 | non-traceable author statement response to hypoxia ; GO:0001666 | inferred from expression pattern inferred from mutant phenotype response to toxic substance ; GO:0009636 | inferred from expression pattern germ cell migration ; GO:0008354 | inferred from mutant phenotype renal tubular secretion ; GO:0097254 | inferred from expression pattern xenobiotic transport ; GO:0042908 | inferred from sequence or structural similarity with UniProtKB:Q00748 ATP-binding cassette (ABC) transporter complex ; GO:0043190 | inferred from sequence or structural similarity with UniProtKB:Q00748 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with UniProtKB:Q00748 integral component of plasma membrane ; GO:0005887 | non-traceable author statement "Mdr49, CG3879, Mes5, MDR49, MDR5, Dm5, mdr49, mrd49" "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR011527:ABC transporter type 1, transmembrane domain, IPR017871:ABC transporter, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG3879 27-Aug-18 DroID_v2018_08 "Drer\abcb11a, Drer\abcb8, Drer\abcb11b, Drer\abcb4, Drer\abcb3l1, Drer\abcb9, Drer\abcb5, Drer\abcb10" Scer\STE6 "Cele\haf-9, Cele\haf-2, Cele\pgp-7, Cele\haf-4, Cele\pgp-10, Cele\pgp-1, Cele\pgp-6, Cele\pgp-5, Cele\pgp-8, Cele\haf-7, Cele\haf-8, Cele\pgp-2, Cele\pgp-12, Cele\pgp-11, Cele\haf-1, Cele\haf-3, Cele\pgp-9, Cele\pgp-4, Cele\pgp-14, Cele\haf-6, Cele\pgp-13, Cele\pgp-3" "Xtro\LOC100494740, Xtro\abcb8" "Mmus\Abcb1a, Mmus\Abcb5, Mmus\Abcb4, Mmus\Abcb11, Mmus\Abcb1b, Mmus\Abcb10, Mmus\Abcb8, Mmus\Abcb9" "Hsap\ABCB1, Hsap\ABCB8, Hsap\ABCB5, Hsap\ABCB11, Hsap\ABCB10, Hsap\ABCB4" embryonic stage | cellular blastoderm mesoderm anlage

viable "germline cell,pole cell" FBgn0086418 l(3)CHb lethal (3) CHb http://flybase.org/reports/FBgn0086418 gene - - - l(3)CHb - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0020297 jockey\gag jockey gag http://flybase.org/reports/FBgn0020297 - transposable_element_gene - - - jockey\gag IPR006579:Pre-C2HC domain - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262333 mir-963 mir-963 stem loop http://flybase.org/reports/FBgn0262333 miRNA_gene - "regulation of feeding behavior ; GO:0060259 | inferred from genetic interaction with mir-959, mir-960, mir-961, mir-962, mir-964 immune response ; GO:0006955 | inferred from genetic interaction with mir-959, mir-960, mir-961, mir-962, mir-964" - "dme-mir-963, mir-963, CR43040, miR-963" - CR43040 27-Aug-18 DroID_v2018_08 - - - - - - "visible,lethal" wing FBgn0019929 Ser7 Ser7 http://flybase.org/reports/FBgn0019929 FBgn0030154 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type peptidase activity ; GO:0008236 | inferred from sequence or structural similarity serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP3, c-SP3, CG2045, SP#2, SP2, Ser7" "IPR018114:Serine proteases, trypsin family, histidine active site, IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site, IPR022700:Proteinase, regulatory CLIP domain" CG2045 27-Aug-18 DroID_v2018_08 Drer\masp2 - "Cele\svh-1, Cele\try-1" - "Mmus\C1s2, Mmus\Klk1b9, Mmus\C1s1, Mmus\Klk1b1, Mmus\Klk1b5" "Hsap\C1S, Hsap\KLK1" viable FBgn0085679 CG41542 - http://flybase.org/reports/FBgn0085679 protein_coding_gene - - - CG41542 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0052506 CG32506 - http://flybase.org/reports/FBgn0052506 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with Evi5 GTPase activator activity ; GO:0005096 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 Rab GTPase binding ; GO:0017137 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 regulation of vesicle fusion ; GO:0031338 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 regulation of GTPase activity ; GO:0043087 | inferred from sequence or structural similarity with Evi5 intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 activation of GTPase activity ; GO:0090630 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 intracellular ; GO:0005622 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 endomembrane system ; GO:0012505 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 CG32506 "IPR000195:Rab-GTPase-TBC domain, IPR004012:RUN domain" CG32506 27-Aug-18 DroID_v2018_08 "Drer\sgsm1b, Drer\sgsm1a, Drer\sgsm2" Scer\GYP7 Cele\tbc-8 "Xtro\sgsm2, Xtro\sgsm1" "Mmus\Sgsm2, Mmus\Sgsm1" "Hsap\SGSM2, Hsap\SGSM1" "viable,fertile" FBgn0025627 CG4194 - http://flybase.org/reports/FBgn0025627 - protein_coding_gene - - - "EG:22E5.6, CG4194" - CG4194 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266136 Gyc76C Guanylyl cyclase at 76C http://flybase.org/reports/FBgn0266136 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719 guanylate cyclase activity ; GO:0004383 | inferred from direct assay receptor activity ; GO:0004872 | inferred from direct assay semaphorin receptor binding ; GO:0030215 | inferred from physical interaction with PlexA protein kinase activity ; GO:0004672 | NOT inferred from sequence or structural similarity with CG10738 guanylate cyclase activity ; GO:0004383 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 peptide receptor activity ; GO:0001653 | inferred from physical interaction with Nplp1 "protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR001245 motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype larval somatic muscle development ; GO:0007526 | inferred from mutant phenotype axon guidance ; GO:0007411 | inferred from genetic interaction with PlexA response to salt stress ; GO:0009651 | inferred from mutant phenotype cGMP-mediated signaling ; GO:0019934 | inferred from direct assay salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype inferred from genetic interaction with LanB2 extracellular matrix organization ; GO:0030198 | inferred from mutant phenotype regulation of BMP signaling pathway ; GO:0030510 | inferred from mutant phenotype cGMP biosynthetic process ; GO:0006182 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 primary branching, open tracheal system ; GO:0007428 | inferred from mutant phenotype axon midline choice point recognition ; GO:0016199 | inferred from genetic interaction with Sema1a inferred from genetic interaction with PlexA" integral component of plasma membrane ; GO:0005887 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 "CG42636, CG8742, gyc76C, Gyc76C, l(3)76BDl, DrGC-1, GYC 76C, DGC1, drgc, CG32215, l(3)L0090, gim" "IPR029787:Nucleotide cyclase, IPR018297:Adenylyl cyclase class-4/guanylyl cyclase, conserved site, IPR000719:Protein kinase domain, IPR001054:Adenylyl cyclase class-3/4/guanylyl cyclase, IPR001828:Receptor, ligand binding region, IPR011009:Protein kinase-like domain, IPR001245:Serine-threonine/tyrosine-protein kinase, catalytic domain, IPR028082:Periplasmic binding protein-like I" CG42636 27-Aug-18 DroID_v2018_08 "Drer\gucy2g, Drer\npr3, Drer\si:dkey-37g12.1, Drer\si:ch73-139e5.4, Drer\gucy2c, Drer\npr1a, Drer\ints3, Drer\gc2, Drer\gc3, Drer\npr1b, Drer\npr2, Drer\gucy2f" - "Cele\gcy-20, Cele\gcy-21, Cele\gcy-11, Cele\gcy-29, Cele\gcy-4, Cele\gcy-19, Cele\gcy-2, Cele\gcy-12, Cele\gcy-9, Cele\gcy-1, Cele\gcy-6, Cele\gcy-17, Cele\gcy-25, Cele\gcy-14, Cele\Y92H12A.4, Cele\gcy-28, Cele\gcy-7, Cele\gcy-22, Cele\gcy-5, Cele\gcy-8, Cele\gcy-18, Cele\gcy-13, Cele\gcy-27, Cele\gcy-15, Cele\gcy-23, Cele\daf-11, Cele\odr-1, Cele\gcy-3" "Xtro\gucy2d, Xtro\gucy2c, Xtro\gucy2f, Xtro\npr1, Xtro\npr3" "Mmus\Gucy2f, Mmus\Npr1, Mmus\Ints3, Mmus\Gucy2d, Mmus\Gucy2e, Mmus\Gucy2c, Mmus\Npr2, Mmus\Npr3, Mmus\Gucy2g" "Hsap\GUCY2D, Hsap\GUCY2F, Hsap\GUCY2C, Hsap\NPR2, Hsap\NPR3, Hsap\NPR1, Hsap\INTS3" " embryonic stage -- adult stage , adult stage , embryonic stage | late , adult stage && oogenesis stage , embryonic stage | early " " adult midgut

, adult brain

, adult proventriculus

, embryonic/larval somatic muscle

, retina

, larval visceral muscle

, oocyte

, optic lobe

, pupal/adult digestive system

,

ubiquitous " FBgn0039798 CG11313 - http://flybase.org/reports/FBgn0039798 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 hemolymph coagulation ; GO:0042381 | inferred from expression pattern proteolysis ; GO:0006508 | inferred from sequence model" extracellular region ; GO:0005576 | inferred from direct assay "CG11313, SP11, c-SP11" "IPR001314:Peptidase S1A, chymotrypsin family, IPR001254:Serine proteases, trypsin domain, IPR018114:Serine proteases, trypsin family, histidine active site, IPR009003:Peptidase S1, PA clan, IPR022700:Proteinase, regulatory CLIP domain, IPR033116:Serine proteases, trypsin family, serine active site" CG11313 27-Aug-18 DroID_v2018_08 Drer\st14b - "Cele\svh-1, Cele\try-1" - "Mmus\Klk1b1, Mmus\Klk1b5" Hsap\KLK1 FBgn0032394 Hacd1 - http://flybase.org/reports/FBgn0032394 protein_coding_gene enzyme binding ; GO:0019899 | inferred from sequence or structural similarity with HGNC:9639 fatty acid elongation ; GO:0030497 | inferred from sequence or structural similarity with HGNC:9639 endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with HGNC:9639 "CG6746, HADC[CG6746]" "IPR007482:Protein-tyrosine phosphatase-like, PTPLA" CG6746 27-Aug-18 DroID_v2018_08 "Drer\hacd1, Drer\hacd3, Drer\hacd2" Scer\PHS1 Cele\hpo-8 "Xtro\hacd2, Xtro\hacd1" "Mmus\Hacd3, Mmus\Hacd4, Mmus\Hacd1, Mmus\Hacd2" "Hsap\HACD3, Hsap\HACD1, Hsap\HACD4, Hsap\HACD2" lethal FBgn0014870 Psi P-element somatic inhibitor http://flybase.org/reports/FBgn0014870 - protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P17133 mRNA binding ; GO:0003729 | inferred from direct assay "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR015096 regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype negative regulation of mRNA splicing, via spliceosome ; GO:0048025 | inferred from direct assay negative regulation of mRNA splicing, via spliceosome ; GO:0048025 | inferred from mutant phenotype mRNA processing ; GO:0006397 | inferred from direct assay regulation of mRNA splicing, via spliceosome ; GO:0048024 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay U1 snRNP ; GO:0005685 | colocalizes_with inferred from physical interaction with snRNP-U1-70K "PSI, EG:EG0003.2, CG8912, Psi" "IPR004087:K Homology domain, IPR004088:K Homology domain, type 1, IPR015096:Far upstream element-binding protein, C-terminal" CG8912 27-Aug-18 DroID_v2018_08 "Drer\fubp1, Drer\fubp3, Drer\khsrp" - "Cele\M01A10.1, Cele\C12D8.1, Cele\tofu-7, Cele\C36E6.1, Cele\ZK418.9" "Xtro\fubp3, Xtro\fubp1, Xtro\khsrp" "Mmus\Fubp3, Mmus\Khsrp, Mmus\Fubp1" "Hsap\FUBP1, Hsap\FUBP3, Hsap\KHSRP" " embryonic stage | early , embryonic stage -- adult stage , oogenesis stage && adult stage | female , embryonic stage | 2-8 hr " ovary

"wild-type,courtship behavior defective,mating defective,sterile,male,meiotic cell cycle defective,lethal - all die before end of larval stage,recessive,some die during larval stage,viable,visible" "spermatid,onion stage spermatid,testis,trichogen cell" DRSC07519 I -1.171608483 1.756830099 0.162208376 0.304035022 -0.703060183 -0.937862654 FBgn0267303 lncRNA:CR45739 - http://flybase.org/reports/FBgn0267303 non_protein_coding_gene - - - CR45739 - CR45739 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085515 CG40758 - http://flybase.org/reports/FBgn0085515 protein_coding_gene - - - CG40758 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265065 asRNA:CR44176 - http://flybase.org/reports/FBgn0265065 non_protein_coding_gene - - - CR44176 - CR44176 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036337 AdenoK Adenosine Kinase http://flybase.org/reports/FBgn0036337 protein_coding_gene adenosine kinase activity ; GO:0004001 | inferred from biological aspect of ancestor with PANTHER:PTN000062161 adenosine kinase activity ; GO:0004001 | inferred from sequence or structural similarity with MGI:MGI:87930 adenosine salvage ; GO:0006169 | inferred from biological aspect of ancestor with PANTHER:PTN000062161 AMP biosynthetic process ; GO:0006167 | inferred from sequence or structural similarity with MGI:MGI:87930 nucleoplasm ; GO:0005654 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "CG11255, DmAdk2, AdenoK" "IPR001805:Adenosine kinase, IPR002173:Carbohydrate/puine kinase, PfkB, conserved site, IPR011611:Carbohydrate kinase PfkB, IPR029056:Ribokinase-like" CG11255 27-Aug-18 DroID_v2018_08 "Drer\rbm4.2, Drer\zgc:77262, Drer\adkb, Drer\adka" Scer\ADO1 Cele\R07H5.8 Xtro\adk Mmus\Adk Hsap\ADK "viable,fertile,long lived" FBgn0060832 l(3)S050115b lethal (3) S050115b http://flybase.org/reports/FBgn0060832 gene - - - "0501/15, l(3)S050115b, l(3)s050115" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of P-stage,recessive,some die during pharate adult stage" FBgn0014047 Su(tor)2-191 Su(tor)2-191 http://flybase.org/reports/FBgn0014047 - gene - - - Su(tor)2-191 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264520 ff4 - http://flybase.org/reports/FBgn0264520 gene - - - ff4 - - 27-Aug-18 DroID_v2018_08 - - - - - - "meiotic cell cycle defective,male,mitotic cell cycle defective" spermatid FBgn0084352 l(3)S012805 l(3)S012805 http://flybase.org/reports/FBgn0084352 gene - - - l(3)S012805 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0024621 meso2 meso2 http://flybase.org/reports/FBgn0024621 FBgn0024481 gene - - - "Clone2, meso2" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032434 CG5421 - http://flybase.org/reports/FBgn0032434 protein_coding_gene "proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from electronic annotation with InterPro:IPR008388 proton-transporting ATP synthase activity, rotational mechanism ; GO:0046933 | inferred from electronic annotation with InterPro:IPR008388" ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from electronic annotation with InterPro:IPR008388 "proton-transporting V-type ATPase, V1 domain ; GO:0033180 | inferred from electronic annotation with InterPro:IPR008388" CG5421 "IPR008388:ATPase, V1 complex, subunit S1" CG5421 27-Aug-18 DroID_v2018_08 "Drer\atp6ap1la, Drer\atp6ap1a, Drer\atp6ap1lb, Drer\atp6ap1b" - Cele\vha-19 Xtro\atp6ap1.2 "Mmus\Atp6ap1l, Mmus\Atp6ap1" "Hsap\ATP6AP1, Hsap\ATP6AP1L" FBgn0001065 fs(3)T female sterile of Tabriz http://flybase.org/reports/FBgn0001065 - gene - - - fs(3)T - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive,eye color defective" "female reproductive system,pigment cell" FBgn0038861 CG7009 - http://flybase.org/reports/FBgn0038861 protein_coding_gene tRNA methyltransferase activity ; GO:0008175 | inferred from electronic annotation with InterPro:IPR028590 RNA methylation ; GO:0001510 | inferred from electronic annotation with InterPro:IPR015507 tRNA processing ; GO:0008033 | inferred from electronic annotation with InterPro:IPR028590 - CG7009 "IPR002877:Ribosomal RNA methyltransferase FtsJ domain, IPR015507:Ribosomal RNA large subunit methyltransferase E, IPR028590:tRNA (cytidine(32)/guanosine(34)-2-O)-methyltransferase, Trm7, IPR029063:S-adenosyl-L-methionine-dependent methyltransferase" CG7009 27-Aug-18 DroID_v2018_08 Drer\ftsj1 Scer\TRM7 "Cele\Y40D12A.1, Cele\R74.7" Xtro\ftsj1 Mmus\Ftsj1 Hsap\FTSJ1 "viable,fertile" FBgn0083082 l(4)B6-C1 lethal (4) B6-C1 http://flybase.org/reports/FBgn0083082 gene - - - l(4)B6-C1 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0005739 l(1)TK229 lethal (1) TK229 http://flybase.org/reports/FBgn0005739 - gene - - - "l229, l(1)TK229" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" "eye,lamina" FBgn0020294 ko knockout http://flybase.org/reports/FBgn0020294 - protein_coding_gene molecular_function ; GO:0003674 | no biological data available motor neuron axon guidance ; GO:0008045 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG10573, ko" "IPR019391:Storkhead-box protein, winged-helix domain" CG10573 27-Aug-18 DroID_v2018_08 "Drer\stox1, Drer\stox2b, Drer\stox2a" - Cele\ham-1 "Xtro\stox2, Xtro\stox1" "Mmus\Stox1, Mmus\Stox2" "Hsap\STOX1, Hsap\STOX2" "viable,fertile,neuroanatomy defective" "RP5 motor neuron,RP3 motor neuron" FBgn0053428 5SrRNA:CR33428 5SrRNA:CR33428 http://flybase.org/reports/FBgn0053428 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33428, 5SrRNA:CR33428" - CR33428 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266363 CG45011 - http://flybase.org/reports/FBgn0266363 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG45011 IPR002350:Kazal domain CG45011 27-Aug-18 DroID_v2018_08 "Drer\tmeff2b, Drer\tmeff2a, Drer\tmeff1b, Drer\si:dkey-203a12.7" - Cele\ZK813.6 Xtro\tmeff1 "Mmus\Tmeff1, Mmus\Tmeff2" "Hsap\TMEFF1, Hsap\TMEFF2" FBgn0052441 CG32441 - http://flybase.org/reports/FBgn0052441 protein_coding_gene - - ER membrane protein complex ; GO:0072546 | inferred from biological aspect of ancestor with PANTHER:PTN001468346 "CG7783, CG32441" IPR029615:ER membrane protein complex subunit 10 CG32441 27-Aug-18 DroID_v2018_08 Drer\emc10 - Cele\Y43F8C.7 Xtro\emc10 Mmus\Emc10 Hsap\EMC10 "viable,fertile,visible" "trichogen cell,mesothoracic tergum" FBgn0028191 l(3)S022930 lethal (3) S022930 http://flybase.org/reports/FBgn0028191 gene - - - "0229/30, l(3)S022930" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive,lethal" FBgn0065617 l(2)SH0817 lethal (2) SH0817 http://flybase.org/reports/FBgn0065617 gene - - - l(2)SH0817 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0043490 en::onecut en::onecut http://flybase.org/reports/FBgn0043490 engineered_fusion_gene - - - en::onecut - - 27-Aug-18 DroID_v2018_08 - - - - - - "eye,eye photoreceptor cell,retina,optic lobe" FBgn0003698 thiv thickened veins http://flybase.org/reports/FBgn0003698 - gene - - - "thi, thiv" - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive,cold sensitive" FBgn0038735 CG4662 - http://flybase.org/reports/FBgn0038735 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 - - CG4662 "IPR002048:EF-hand domain, IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site" CG4662 27-Aug-18 DroID_v2018_08 "Drer\micu1, Drer\micu2, Drer\micu3a, Drer\micu3b" - Cele\C56A3.6 "Xtro\micu3, Xtro\micu1, Xtro\micu2" "Mmus\Micu3, Mmus\Micu1, Mmus\Micu2" "Hsap\MICU1, Hsap\MICU2, Hsap\MICU3" "viable,fertile" FBgn0005352 su(Cy)r "suppressor of Curly, recessive" http://flybase.org/reports/FBgn0005352 - gene - - - "su(Cy)r, su(Cy)" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0016692 Pas Partial sevenless http://flybase.org/reports/FBgn0016692 - gene molecular_function ; GO:0003674 | no biological data available central nervous system development ; GO:0007417 | inferred from mutant phenotype compound eye photoreceptor development ; GO:0042051 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available Pas - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" "presumptive embryonic/larval central nervous system,rhabdomere" FBgn0045973 PdL72A3 PdL72A3 http://flybase.org/reports/FBgn0045973 gene - - - PdL72A3 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0014090 anon-31Ea anonymous at 31E-a http://flybase.org/reports/FBgn0014090 - gene - - - anon-31Ea - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267136 lncRNA:CR45576 - http://flybase.org/reports/FBgn0267136 non_protein_coding_gene - - - "lincRNA.738, CR45576" - CR45576 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0261592 RpS6 Ribosomal protein S6 http://flybase.org/reports/FBgn0261592 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from direct assay structural constituent of ribosome ; GO:0003735 | traceable author statement "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR001377, InterPro:IPR014401, InterPro:IPR018282 cytoplasmic translation ; GO:0002181 | inferred by curator from GO:0022626 rRNA processing ; GO:0006364 | inferred from biological aspect of ancestor with PANTHER:PTN000161291 cytoplasmic translation ; GO:0002181 | traceable author statement ribosomal small subunit biogenesis ; GO:0042274 | inferred from biological aspect of ancestor with PANTHER:PTN000161291 centrosome duplication ; GO:0051298 | inferred from mutant phenotype immune response ; GO:0006955 | traceable author statement" ribosome ; GO:0005840 | inferred from direct assay cytosolic small ribosomal subunit ; GO:0022627 | traceable author statement cytosolic ribosome ; GO:0022626 | inferred from direct assay "RpS6, CG10944, M(1)7BC, M(1)7C, S6, DS6, air8, rps6, pp30, rpS6, air[8], l(1)air[8], l(1)air8, hen, l(1)hen, anon-WO02059370.61, RPS6, Rps6, (Rp)S6, Rp S6" "IPR018282:Ribosomal protein S6e, conserved site, IPR001377:Ribosomal protein S6e, IPR014401:Ribosomal protein S6, eukaryotic" CG10944 27-Aug-18 DroID_v2018_08 "Drer\rps6, Drer\zgc:112083, Drer\hinfp" "Scer\RPS6A, Scer\RPS6B" "Cele\rps-6, Cele\hinf-1" "Xtro\hinfp, Xtro\rps6" "Mmus\Hinfp, Mmus\Rps6" Hsap\RPS6 embryonic stage -- adult stage DRSC18712 EK -1.315846862 -1.054685785 0.72029246 -3.624350145 1.87134093 4.108212097 FBgn0014896 anon-10Ac anon-10Ac http://flybase.org/reports/FBgn0014896 - gene - - - anon-10Ac - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260311 GSd477 - http://flybase.org/reports/FBgn0260311 gene - - - GSd477 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0028139 l(3)S048301a lethal (3) S048301a http://flybase.org/reports/FBgn0028139 gene - - - "0483/01, l(3)S048301, l(3)S048301a" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0067372 l(2)NC14 lethal (2) NC14 http://flybase.org/reports/FBgn0067372 gene - - - l(2)NC14 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0265878 lncRNA:CR44667 - http://flybase.org/reports/FBgn0265878 non_protein_coding_gene - - - "CR44667, lincRNA.367" - CR44667 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0063384 snoRNA:U29:54Eb snoRNA:U29:54Eb http://flybase.org/reports/FBgn0063384 snoRNA_gene - - - "U29snoRNA, CR32890, snoRNA:U29:54Eb, DmSnR71a" - CR32890 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0015029 CU61 Cible d'Ubx 61 http://flybase.org/reports/FBgn0015029 - gene - - - "61, Cu61, CU61" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002183 dre4 dre4 http://flybase.org/reports/FBgn0002183 FBgn0002182 protein_coding_gene chromatin binding ; GO:0003682 | inferred from direct assay nucleosome binding ; GO:0031491 | inferred from direct assay histone binding ; GO:0042393 | inferred from biological aspect of ancestor with PANTHER:PTN000360139 regulation of chromatin assembly or disassembly ; GO:0001672 | inferred from mutant phenotype DNA replication-independent nucleosome organization ; GO:0034724 | inferred from biological aspect of ancestor with PANTHER:PTN000360139 positive regulation of transcription elongation from RNA polymerase II promoter ; GO:0032968 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype FACT complex ; GO:0035101 | traceable author statement FACT complex ; GO:0035101 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "Spt16, dSPT16, spt16, dspt16, DRE4/dSPT16, l(3)dre4, l(3)62Bg, CG1828, dre4, dSpt16, SPT16, Dre4, DRE4" "IPR000994:Peptidase M24, IPR013719:Domain of unknown function DUF1747, IPR013953:FACT complex subunit Spt16p/Cdc68p, IPR033825:FACT complex subunit SPT16, IPR029149:Creatinase/Aminopeptidase P/Spt16, N-terminal, IPR029148:FACT complex subunit Spt16, N-terminal lobe domain" CG1828 27-Aug-18 DroID_v2018_08 Drer\supt16h Scer\SPT16 "Cele\F55A3.7, Cele\F55A3.3" Xtro\supt16h Mmus\Supt16 Hsap\SUPT16H "lethal,heat sensitive,recessive,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of larval stage,some die during larval stage,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" DRSC08714 I -3.721266813 -1.380521877 -0.547079818 -0.614702853 -1.109159874 0.284282458 FBgn0046665 anon-38C.32 anon-38C.32 http://flybase.org/reports/FBgn0046665 gene - - - "38C.32, anon-38C.32" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002617 M(3)76A Minute (3) 76A http://flybase.org/reports/FBgn0002617 - gene - - - "M(3)S34, M(3)76A" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0022323 l(1)B22.5 lethal (1) B22.5 http://flybase.org/reports/FBgn0022323 - gene - - - "B22.5, l(1)B22.5" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0039703 CG7829 - http://flybase.org/reports/FBgn0039703 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "SP136, CG7829" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site" CG7829 27-Aug-18 DroID_v2018_08 Drer\si:ch211-165b19.8 - "Cele\try-1, Cele\svh-1" - "Mmus\Prss55, Mmus\Cfd, Mmus\Prss53, Mmus\Prss36" "Hsap\PRSS36, Hsap\PRSS53, Hsap\CFD" viable FBgn0085723 CG41616 - http://flybase.org/reports/FBgn0085723 protein_coding_gene - - - CG41616 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264717 lncRNA:CR43985 - http://flybase.org/reports/FBgn0264717 non_protein_coding_gene - - - CR43985 - CR43985 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0011106 l(1)Q67 lethal (1) Q67 http://flybase.org/reports/FBgn0011106 FBgn0010210 gene - - - l(1)Q67 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0042157 CG18834 - http://flybase.org/reports/FBgn0042157 protein_coding_gene - - - CG18834 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065233 l(2)SH2168 lethal (2) SH2168 http://flybase.org/reports/FBgn0065233 gene - - - l(2)SH2168 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0261563 wb wing blister http://flybase.org/reports/FBgn0261563 protein_coding_gene - imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype digestive tract mesoderm development ; GO:0007502 | inferred from mutant phenotype gonad development ; GO:0008406 | inferred from mutant phenotype basal lamina ; GO:0005605 | inferred from sequence or structural similarity basement membrane ; GO:0005604 | inferred from sequence or structural similarity "wb, l(2)br1, A1, l(2)34Fb, l(2)09437, CG15288, BEST:CK02229, BG:DS03792.2, CG32970, CG42677, alpha[[1,2]], CT35236, LM-A/alpha2, BG:DS03792.1, CK02229, DLAM, l34Fb, fus5, LanA1,2, &agr1,2Lan" "IPR000034:Laminin IV, IPR001791:Laminin G domain, IPR002049:Laminin EGF domain, IPR008211:Laminin, N-terminal, IPR013032:EGF-like, conserved site, IPR013320:Concanavalin A-like lectin/glucanase domain, IPR008979:Galactose-binding domain-like, IPR015943:WD40/YVTN repeat-like-containing domain, IPR000742:EGF-like domain" CG42677 27-Aug-18 DroID_v2018_08 "Drer\ntn1b, Drer\lama4, Drer\lama2, Drer\ush2a, Drer\lama1, Drer\lamc3, Drer\lamc1, Drer\lama5, Drer\ntn5, Drer\ntn2" Scer\IMH1 Cele\lam-3 "Xtro\lama2, Xtro\lama3, Xtro\ntn3, Xtro\lama1, Xtro\lama5, Xtro\lamc2, Xtro\lama4, Xtro\lamc1, Xtro\ntn1" "Mmus\Lama4, Mmus\Ush2a, Mmus\Lamc2, Mmus\Lama2, Mmus\Lama3, Mmus\Lamc1, Mmus\Lamc3, Mmus\Ntn1, Mmus\Ntng1, Mmus\Lama1, Mmus\Lama5, Mmus\Ntn3" "Hsap\LAMA4, Hsap\LAMA5, Hsap\NTN1, Hsap\LAMA3, Hsap\LAMC3, Hsap\LAMC2, Hsap\NTNG1, Hsap\NTN3, Hsap\LAMC1, Hsap\USH2A, Hsap\LAMA1, Hsap\LAMA2" " embryonic stage | early , embryonic stage | stage >12 , embryonic stage | stage 14 , embryonic stage -- adult stage , embryonic stage | stage 9-11 , adult stage && oogenesis stage " "

ubiquitous , visceral mesoderm

, alary cell

, muscle attachment site | vicinity of

, oocyte

, nurse cell

" " larval stage | third instar , embryonic stage | stage >14 , embryonic stage | stage 14 , embryonic stage | stage 10 , embryonic stage | stage >=12 " " dorsal mesothoracic disc | restricted

, ventral nerve cord | dorsal

, muscle attachment site

, mesectoderm

, visceral mesoderm

" DRSC23003 K 1.318098992 1.740092199 FBgn0265697 lncRNA:CR44504 - http://flybase.org/reports/FBgn0265697 non_protein_coding_gene - - - "CR44504, pri-mir-6-3_mir-6-2_mir-6-1_mir-5_mir-4_mir-286_mir-3_mir-309" - CR44504 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033631 Sod3 Superoxide dismutase 3 http://flybase.org/reports/FBgn0033631 protein_coding_gene superoxide dismutase activity ; GO:0004784 | inferred from biological aspect of ancestor with PANTHER:PTN000000113 superoxide dismutase activity ; GO:0004784 | inferred from direct assay superoxide dismutase activity ; GO:0004784 | inferred from mutant phenotype copper ion binding ; GO:0005507 | inferred from biological aspect of ancestor with PANTHER:PTN000000113 zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000000113 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001424, InterPro:IPR018152 response to oxidative stress ; GO:0006979 | inferred from mutant phenotype UV protection ; GO:0009650 | inferred from direct assay removal of superoxide radicals ; GO:0019430 | inferred from mutant phenotype removal of superoxide radicals ; GO:0019430 | inferred from biological aspect of ancestor with PANTHER:PTN000000113" extracellular space ; GO:0005615 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000000114 plasma membrane ; GO:0005886 | inferred from direct assay "CG13200, CT25938, Sod3, dSod3, Dmel/CG9027, CG9027, SOD3" "IPR001424:Superoxide dismutase, copper/zinc binding domain, IPR018152:Superoxide dismutase, copper/zinc, binding site" CG9027 27-Aug-18 DroID_v2018_08 "Drer\sod3a, Drer\sod3b, Drer\sod1" "Scer\CCS1, Scer\SOD1" "Cele\sod-4, Cele\sod-5, Cele\sod-1" "Xtro\sod3, Xtro\sod1" "Mmus\Sod1, Mmus\Sod3" "Hsap\SOD3, Hsap\SOD1" "oxidative stress response defective,short lived,viable,body color defective" mesothoracic tergum FBgn0026678 l(1)G0104 lethal (1) G0104 http://flybase.org/reports/FBgn0026678 - gene - - - l(1)G0104 - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0005420 l(1)adl9 lethal (1) adl9 http://flybase.org/reports/FBgn0005420 - gene - - - "l(1)adl-9, l(1)adl9" - - 27-Aug-18 DroID_v2018_08 - - - - - - "short lived,heat sensitive,partially lethal - majority die,lethal" FBgn0032061 CG9314 - http://flybase.org/reports/FBgn0032061 protein_coding_gene heme binding ; GO:0020037 | inferred from biological aspect of ancestor with PANTHER:PTN000157250 catalase activity ; GO:0004096 | inferred from sequence or structural similarity with UniProtKB:P04762 catalase activity ; GO:0004096 | inferred from biological aspect of ancestor with PANTHER:PTN000157250 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR011614, InterPro:IPR018028, InterPro:IPR020835, InterPro:IPR024711 response to hydrogen peroxide ; GO:0042542 | inferred from biological aspect of ancestor with PANTHER:PTN000157250 hydrogen peroxide catabolic process ; GO:0042744 | inferred from biological aspect of ancestor with PANTHER:PTN000157250 response to oxidative stress ; GO:0006979 | inferred from sequence or structural similarity with UniProtKB:P04762" peroxisome ; GO:0005777 | inferred from biological aspect of ancestor with PANTHER:PTN000157252 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000157252 "CT26521, anon-WO0140519.249, CG9314, CatB" "IPR002226:Catalase haem-binding site, IPR011614:Catalase core domain, IPR010582:Catalase immune-responsive domain, IPR018028:Catalase, mono-functional, haem-containing, IPR020835:Catalase-like domain, IPR024711:Catalase, mono-functional, haem-containing, clades 1 and 3" CG9314 27-Aug-18 DroID_v2018_08 Drer\cat "Scer\CTT1, Scer\CTA1" "Cele\ctl-3, Cele\ctl-1, Cele\ctl-2" "Xtro\cat.2, Xtro\cat.1" Mmus\Cat Hsap\CAT "viable,visible" "adult heart,RU486 conditional,trichogen cell" FBgn0065175 l(3)SH016 lethal (3) SH016 http://flybase.org/reports/FBgn0065175 gene - - - "l(3)SH016, l(2)SH3 016" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0037500 CG17944 - http://flybase.org/reports/FBgn0037500 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG17944 - CG17944 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC12572 I 0.753408372 -1.940362737 -0.196981762 0.253008363 0.212101108 0.234536605 FBgn0040509 ACXB ACXB http://flybase.org/reports/FBgn0040509 protein_coding_gene adenylate cyclase activity ; GO:0004016 | inferred from sequence model adenylate cyclase activity ; GO:0004016 | non-traceable author statement guanylate cyclase activity ; GO:0004383 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR001054 spermatogenesis ; GO:0007283 | inferred from expression pattern signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 cGMP biosynthetic process ; GO:0006182 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 "guanylate cyclase complex, soluble ; GO:0008074 | inferred from biological aspect of ancestor with PANTHER:PTN000229249 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000228924 integral component of membrane ; GO:0016021 | inferred from sequence model" "CG17174, AC, DACXB, AC34A, Ac34A, ACXB" "IPR029787:Nucleotide cyclase, IPR001054:Adenylyl cyclase class-3/4/guanylyl cyclase" CG17174 27-Aug-18 DroID_v2018_08 "Drer\adcy1a, Drer\adcy2a, Drer\adcy3a, Drer\adcy7, Drer\adcy2b, Drer\si:dkey-206f10.1, Drer\adcy6a, Drer\adcy1b, Drer\adcy5, Drer\adcy6b, Drer\si:ch211-132f19.7, Drer\adcy8" - "Cele\acy-4, Cele\acy-2" "Xtro\dnajc27, Xtro\adcy6, Xtro\adcy7, Xtro\adcy1, Xtro\adcy4" "Mmus\Adcy5, Mmus\Adcy1, Mmus\Adcy2, Mmus\Adcy3, Mmus\Adcy4, Mmus\Adcy8, Mmus\Adcy7, Mmus\Adcy6" "Hsap\ADCY5, Hsap\ADCY1, Hsap\ADCY7, Hsap\ADCY6, Hsap\ADCY3, Hsap\ADCY4, Hsap\ADCY2, Hsap\ADCY8" " pupal stage , larval stage | late , adult stage | male && spermatogenesis , adult stage | male " " spermatid | early

, spermatocyte

" viable FBgn0028128 l(3)S056113 lethal (3) S056113 http://flybase.org/reports/FBgn0028128 gene - - - "0561/13, l(3)S056113" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0051036 CG31036 - http://flybase.org/reports/FBgn0051036 protein_coding_gene - - cilium ; GO:0005929 | colocalizes_with inferred from direct assay "CG15518, CG15516, CG31036" - CG31036 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0028977 v(2)k06408 v(2)k06408 http://flybase.org/reports/FBgn0028977 gene - - - v(2)k06408 - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive" FBgn0061066 l(3)S020202 lethal (3) S020202 http://flybase.org/reports/FBgn0061066 gene - - - "0202/02, l(3)S020202" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0064237 Idgf5 Imaginal disc growth factor 5 http://flybase.org/reports/FBgn0064237 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR011583 imaginal disc growth factor receptor binding ; GO:0008084 | inferred from direct assay "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR001223, InterPro:IPR013781 chitin-based cuticle development ; GO:0040003 | inferred from mutant phenotype wound healing ; GO:0042060 | inferred from mutant phenotype imaginal disc development ; GO:0007444 | inferred from direct assay" extracellular region ; GO:0005576 | inferred from direct assay extracellular region ; GO:0005576 | non-traceable author statement "CG5154, IDGF-5, IDGF5, Idgf5, IDGF, Cht14, DmIDGF5, idgf5" "IPR001223:Glycoside hydrolase family 18, catalytic domain, IPR011583:Chitinase II, IPR017853:Glycoside hydrolase superfamily, IPR029070:Chitinase insertion domain" CG5154 27-Aug-18 DroID_v2018_08 "Drer\chia.4, Drer\chia.3, Drer\ovgp1, Drer\si:ch211-226m16.2, Drer\chia.6, Drer\chia.5, Drer\chia.2" Scer\CTS2 "Cele\chil-23, Cele\chil-24, Cele\chil-20, Cele\chil-25, Cele\cht-2, Cele\chil-11, Cele\chil-16, Cele\chil-17, Cele\chil-19, Cele\T19H5.6, Cele\chil-5, Cele\chil-15, Cele\lmd-4, Cele\chil-6, Cele\lmd-5, Cele\chil-7, Cele\chil-8, Cele\chil-18, Cele\chil-12, Cele\chil-22, Cele\chil-3, Cele\chil-4, Cele\chil-2, Cele\chil-13" "Xtro\chia, Xtro\LOC548945, Xtro\ctbs, Xtro\chit1" "Mmus\Chil4, Mmus\Ctbs, Mmus\Chit1, Mmus\Chil6, Mmus\Chil3, Mmus\Chil5, Mmus\Ovgp1, Mmus\Chia1, Mmus\Chil1" "Hsap\CHI3L2, Hsap\OVGP1, Hsap\CHIT1, Hsap\CHIA, Hsap\CHI3L1" viable FBgn0030339 Cyp28c1 Cyp28c1 http://flybase.org/reports/FBgn0030339 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 oxidoreductase activity ; GO:0016491 | inferred from biological aspect of ancestor with PANTHER:PTN001209891" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972" - "28c1, CG1895, Cyp28c1" "IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I, IPR017972:Cytochrome P450, conserved site" CG1895 27-Aug-18 DroID_v2018_08 "Drer\cyp3c3, Drer\cyp19a1b, Drer\cyp26b1, Drer\cyp46a1.4, Drer\cyp4f3, Drer\cyp3c2, Drer\cyp26c1, Drer\LOC100329425, Drer\cyp3a65, Drer\cyp4v7, Drer\cyp46a1.1, Drer\cyp46a1.3, Drer\cyp4v8, Drer\cyp19a1a, Drer\cyp26a1, Drer\cyp3c1, Drer\cyp20a1, Drer\tbxas1, Drer\cyp3c4, Drer\cyp46a1.2, Drer\cyp4t8" "Scer\ERG11, Scer\ERG5, Scer\DIT2" "Cele\cyp-25A6, Cele\cyp-13A12, Cele\cyp-25A3, Cele\cyp-13A2, Cele\cyp-13A6, Cele\cyp-13A5, Cele\cyp-13A10, Cele\cyp-13B2, Cele\cyp-13A11, Cele\cyp-13A4, Cele\cyp-44A1, Cele\cyp-25A2, Cele\cyp-13A7, Cele\cyp-25A4, Cele\cyp-13A3, Cele\cyp-13A1, Cele\cyp-43A1, Cele\cyp-13B1, Cele\cyp-25A1, Cele\cyp-13A8" "Xtro\mgc108213, Xtro\cyp3a4, Xtro\cyp19a1, Xtro\cyp4b1, Xtro\LOC100494419, Xtro\cyp4f2, Xtro\cyp4b1.2, Xtro\cyp26c1, Xtro\LOC100488227, Xtro\cyp26b1, Xtro\cyp3a5, Xtro\cyp4v2, Xtro\cyp26a1, Xtro\LOC100487918, Xtro\cyp20a1, Xtro\cyp4f22, Xtro\tbxas1" "Mmus\Cyp4f13, Mmus\Cyp3a13, Mmus\Cyp4f39, Mmus\Cyp4f15, Mmus\Cyp4x1, Mmus\Cyp4f14, Mmus\Tbxas1, Mmus\Cyp46a1, Mmus\Cyp4a12a, Mmus\Cyp26c1, Mmus\Cyp3a44, Mmus\Cyp3a41b, Mmus\Cyp3a59, Mmus\Cyp4a31, Mmus\Cyp19a1, Mmus\Cyp4a14, Mmus\Cyp4f18, Mmus\Cyp4a10, Mmus\Cyp3a25, Mmus\Cyp4a12b, Mmus\Cyp4b1, Mmus\Cyp3a57, Mmus\Cyp4f16, Mmus\Cyp4f17, Mmus\Cyp3a41a, Mmus\Cyp4f40, Mmus\Cyp3a16, Mmus\Cyp4a32, Mmus\Cyp3a11, Mmus\Cyp26a1, Mmus\Cyp4f37, Mmus\Cyp20a1, Mmus\Cyp26b1, Mmus\Cyp4v3" "Hsap\CYP4A22, Hsap\CYP3A5, Hsap\CYP3A4, Hsap\CYP19A1, Hsap\CYP26B1, Hsap\CYP3A7-CYP3A51P, Hsap\CYP4X1, Hsap\CYP4V2, Hsap\CYP46A1, Hsap\CYP4F11, Hsap\CYP26C1, Hsap\CYP3A43, Hsap\CYP20A1, Hsap\CYP4F12, Hsap\TBXAS1, Hsap\CYP4F22, Hsap\CYP4F3, Hsap\CYP4B1, Hsap\CYP4A11, Hsap\CYP4F2, Hsap\CYP4Z1, Hsap\CYP26A1" FBgn0262375 mir-1005 mir-1005 stem loop http://flybase.org/reports/FBgn0262375 miRNA_gene - - - "mir-1005, dme-mir-1005, CR42895, miR-1005" - CR42895 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0036617 Cpr72Ea Cuticular protein 72Ea http://flybase.org/reports/FBgn0036617 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr72Ea, CG4818" IPR000618:Insect cuticle protein CG4818 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" FBgn0026083 tyf twenty-four http://flybase.org/reports/FBgn0026083 FBgn0026082 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Atx2 positive regulation of translation ; GO:0045727 | inferred from direct assay locomotor rhythm ; GO:0045475 | inferred from mutant phenotype defense response to bacterium ; GO:0042742 | inferred from mutant phenotype - "EG:EG0007.4, EG:EG0007.12, tyf, CG4857, CG485, TYF" - CG4857 27-Aug-18 DroID_v2018_08 - - - - - - "circadian behavior defective,locomotor rhythm defective,viable,fertile,recessive,circadian rhythm defective" embryonic/larval hemocyte | third instar larval stage FBgn0019772 l(1)47 lethal (1) 47 http://flybase.org/reports/FBgn0019772 - gene - - - l(1)47 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0085277 CG34248 - http://flybase.org/reports/FBgn0085277 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34248 - CG34248 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0020314 anon-95ABa anon-95ABa http://flybase.org/reports/FBgn0020314 - gene - - - "10A2, anon-95ABa" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0003102 PL(2)sp-S3 Polygenic locus sternopleural S3 http://flybase.org/reports/FBgn0003102 - gene - - - "PL(2)sp[S3], II, PL(2)sp-S3" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039324 CG10553 - http://flybase.org/reports/FBgn0039324 protein_coding_gene - - - "CT29612, CG10553" "IPR011009:Protein kinase-like domain, IPR015897:CHK kinase-like, IPR004119:Protein of unknown function DUF227" CG10553 27-Aug-18 DroID_v2018_08 Drer\LOC100150280 - "Cele\nhr-246, Cele\C29F7.2, Cele\dhs-27, Cele\F59B1.10, Cele\H06H21.8, Cele\C29F7.1, Cele\F59B1.8" - - - viable FBgn0022310 l(1)J67.3 lethal (1) J67.3 http://flybase.org/reports/FBgn0022310 - gene - - - "J67.3, l(1)J67.3" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0034909 CG4797 - http://flybase.org/reports/FBgn0034909 protein_coding_gene sugar:proton symporter activity ; GO:0005351 | inferred from biological aspect of ancestor with PANTHER:PTN000627328 glucose transmembrane transporter activity ; GO:0005355 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 hexose transmembrane transport ; GO:0035428 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 glucose import ; GO:0046323 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005828, InterPro:IPR005829" CG4797 "IPR005829:Sugar transporter, conserved site, IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG4797 27-Aug-18 DroID_v2018_08 "Drer\slc2a12, Drer\slc2a6, Drer\slc2a8, Drer\soat1, Drer\soat2, Drer\slc2a10, Drer\slc2a13b, Drer\LOC101882338" "Scer\HXT11, Scer\HXT14, Scer\ITR1, Scer\YDR387C, Scer\VBA1, Scer\SGE1, Scer\MAL11, Scer\VBA3, Scer\VBA5, Scer\YDL199C, Scer\HXT7, Scer\YMR279C, Scer\HXT6, Scer\HXT3, Scer\HXT8, Scer\SNF3, Scer\MAL31, Scer\GAL2, Scer\HXT16, Scer\VBA4, Scer\ENB1, Scer\AZR1, Scer\GEX1, Scer\HXT4, Scer\HXT5, Scer\YFL040W, Scer\GEX2, Scer\HXT2, Scer\HXT9, Scer\VBA2, Scer\HXT13, Scer\HXT15, Scer\HXT10, Scer\HXT17, Scer\MPH2, Scer\ITR2, Scer\RGT2, Scer\HXT1, Scer\MPH3, Scer\STL1, Scer\ATR1" Cele\mboa-1 "Xtro\slc2a8, Xtro\slc2a10, Xtro\slc2a12, Xtro\soat1, Xtro\slc2a6, Xtro\soat2" "Mmus\Slc2a6, Mmus\Soat1, Mmus\Soat2, Mmus\Slc2a10, Mmus\Slc2a12, Mmus\Slc2a8, Mmus\Slc2a13" "Hsap\SLC2A6, Hsap\SLC2A13, Hsap\SOAT2, Hsap\SLC2A12, Hsap\SLC2A8, Hsap\SLC2A10, Hsap\SOAT1" "viable,fertile,partially lethal - majority die,visible" mesothoracic tergum FBgn0036474 Or71a Odorant receptor 71a http://flybase.org/reports/FBgn0036474 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 "OR71a, Or71c, 71a, DOR14, 71B.1, CG17871, Or71a, or71a" "IPR004117:Olfactory receptor, insect" CG17871 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0019770 l(1)48B lethal (1) 48B http://flybase.org/reports/FBgn0019770 - gene - - - l(1)48B - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0019638 ApII Apurinic/apyrimidinic endonuclease II http://flybase.org/reports/FBgn0019638 - gene DNA-(apurinic or apyrimidinic site) lyase activity ; GO:0003906 | inferred from direct assay DNA repair ; GO:0006281 | inferred from direct assay - ApII - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002647 mapP midgut amylase pattern PMG http://flybase.org/reports/FBgn0002647 - gene - - - "map, map-PMG, mapP" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034243 Ns2 Nucleostemin 2 http://flybase.org/reports/FBgn0034243 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR006073, InterPro:IPR030378 GTPase activity ; GO:0003924 | inferred from direct assay" positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype phagocytosis ; GO:0006909 | inferred from mutant phenotype nucleolus ; GO:0005730 | colocalizes_with inferred from direct assay nucleolus ; GO:0005730 | inferred from direct assay nucleoplasm ; GO:0005654 | colocalizes_with inferred from direct assay "CG6501, ns2, Ngp, dmNS2, NS2, Ngp1, Ns2" "IPR030378:Circularly permuted (CP)-type guanine nucleotide-binding (G) domain, IPR006073:GTP binding domain, IPR012971:Nucleolar GTP-binding protein 2, N-terminal domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR024929:Nucleolar GTP-binding protein 2, IPR023179:GTP-binding protein, orthogonal bundle domain" CG6501 27-Aug-18 DroID_v2018_08 Drer\gnl2 Scer\NOG2 Cele\ngp-1 Xtro\gnl2 Mmus\Gnl2 Hsap\GNL2 "cell lethalcell lethal,recessive,somatic clone,lethal - all die before end of first instar larval stage,some die during first instar larval stage,lethal,visible,long lived" "wing disc,somatic clone,eye" DRSC06993 E -1.237858552 0.866919167 2.358023133 -0.671870781 -0.299468794 1.283393864 FBgn0002645 Map205 Microtubule-associated protein 205 http://flybase.org/reports/FBgn0002645 - protein_coding_gene microtubule binding ; GO:0008017 | inferred from sequence or structural similarity microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype inferred from genetic interaction with polo centrosome organization ; GO:0051297 | inferred from mutant phenotype spindle ; GO:0005819 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity midbody ; GO:0030496 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay "205K MAP, CG1483, MAP4, 205-kDa MAP, MAP205, 205kDa MAP, 205kD MAP, Map205, map205" - CG1483 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" FBgn0002335 l(3)87Bc lethal (3) 87Bc http://flybase.org/reports/FBgn0002335 - gene - - - "ck15, l(3)ck15, l(3)87Bc" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0011892 tRNA:Lys-CTT-1-6 transfer RNA:Lysine-CTT 1-6 http://flybase.org/reports/FBgn0011892 "FBgn0003796, FBgn0011886, FBgn0011900, FBgn0050300, FBgn0060180" tRNA_gene AAG codon-amino acid adaptor activity ; GO:0033444 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033444 cytosol ; GO:0005829 | inferred by curator from GO:0033444 "tRNA[Lys][[2]], AE002778.trna4-LysCTT, tRNA:K2, tRNA:K4, tRNA:K:CTT:AE002778-d, CR30300, tRNA:lys2:42Ea, tRNAlys, chr2R.trna91-LysCTT, tRNA-Lys-CTT-1-6, tRNA:Lys-CTT-1-6, tRNA:K2:42Ea, AAG" - CR30300 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0015828 TfIIEalpha Transcription factor IIEalpha http://flybase.org/reports/FBgn0015828 - protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR017919 positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:4650 inferred from sequence or structural similarity with SGD:S000001511 inferred from sequence or structural similarity with protein_id:CAA70050.2 transcription factor TFIIE complex ; GO:0005673 | inferred from sequence or structural similarity with HGNC:4650 inferred from sequence or structural similarity with SGD:S000001511 inferred from sequence or structural similarity with protein_id:CAA70050.2 transcription factor TFIIE complex ; GO:0005673 | inferred from physical interaction with TfIIEβ nucleus ; GO:0005634 | inferred from direct assay "TFIIE, TFIIEalpha, TFIIE-L, CG10415, dTFIIEL, dTFIIE-L, TfIIE, TfIIEalpha, TfIIEa" "IPR002853:Transcription initiation factor IIE subunit alpha, N-terminal, IPR017919:Transcription factor TFE/TFIIEalpha HTH domain, IPR024550:TFIIEalpha/SarR/Rpc3 HTH domain, IPR011991:Winged helix-turn-helix DNA-binding domain, IPR021600:Transcription factor TFIIE alpha subunit, C-terminal, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG10415 27-Aug-18 DroID_v2018_08 Drer\gtf2e1 Scer\TFA1 Cele\ZK550.4 "Xtro\gtf2e1, Xtro\gtf2e1.2" Mmus\Gtf2e1 Hsap\GTF2E1 lethal FBgn0086052 snoRNA:Me18S-G423 - http://flybase.org/reports/FBgn0086052 snoRNA_gene - - - "snoRNA:Me18S-G423, Me18S-Gm423, CR34681" - CR34681 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060297 p74S p74S http://flybase.org/reports/FBgn0060297 gene SH2 domain binding ; GO:0042169 | inferred from direct assay - - "p74, p74S" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0025733 sca::Hsap\FGB sca::Hsap\FGB http://flybase.org/reports/FBgn0025733 - engineered_fusion_gene - - - sca::Hsap\FGB - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing,wing vein" FBgn0004857 elA elbow A http://flybase.org/reports/FBgn0004857 FBgn0000569 gene - - - "el, elb, elA, el[A]" - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive,viable" "wing,posterior,wing vein L5,haltere,wing vein L4,alula,dorsal row,costal cell,wing vein L1" FBgn0260062 2L3547 - http://flybase.org/reports/FBgn0260062 gene - - - 2L3547 - - 27-Aug-18 DroID_v2018_08 - - - - - - "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0024752 Fs(2)1 Fs(2)1 http://flybase.org/reports/FBgn0024752 - gene - - - Fs(2)1 - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,female sterile germline-dependent,dominant,viable" "egg,dorsal appendage,nurse cell,chorion" FBgn0042148 CG18825 - http://flybase.org/reports/FBgn0042148 protein_coding_gene - - - CG18825 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0011635 l(2)T57h8 lethal (2) T57h8 http://flybase.org/reports/FBgn0011635 FBgn0005177 gene - - - l(2)T57h8 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0033248 Dic3 Dicarboxylate carrier 3 http://flybase.org/reports/FBgn0033248 protein_coding_gene thiosulfate transmembrane transporter activity ; GO:0015117 | inferred from direct assay oxaloacetate transmembrane transporter activity ; GO:0015131 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 malate transmembrane transporter activity ; GO:0015140 | NOT inferred from direct assay succinate transmembrane transporter activity ; GO:0015141 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 inorganic phosphate transmembrane transporter activity ; GO:0005315 | inferred from direct assay antiporter activity ; GO:0015297 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 sulfate transmembrane transporter activity ; GO:0015116 | inferred from direct assay mitochondrial transport ; GO:0006839 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 malate transmembrane transport ; GO:0071423 | NOT inferred from direct assay thiosulfate transport ; GO:0015709 | inferred from direct assay oxaloacetate transport ; GO:0015729 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 phosphate ion transmembrane transport ; GO:0035435 | inferred from direct assay succinate transmembrane transport ; GO:0071422 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 sulfate transport ; GO:0008272 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000756618 mitochondrion ; GO:0005739 | inferred from direct assay "CG11196, Dic3, Dic3p" "IPR002067:Mitochondrial carrier protein, IPR023395:Mitochondrial carrier domain, IPR018108:Mitochondrial substrate/solute carrier" CG11196 27-Aug-18 DroID_v2018_08 "Drer\mrpl12, Drer\si:ch1073-100f3.2, Drer\slc25a10, Drer\ucp2, Drer\slc25a14, Drer\slc25a11" Scer\DIC1 "Cele\ucp-4, Cele\slc-25A10, Cele\mrpl-12" "Xtro\rangrf, Xtro\ucp1, Xtro\slc25a30, Xtro\slc25a10, Xtro\ucp2, Xtro\slc25a27" "Mmus\Mrpl12, Mmus\Ucp2, Mmus\Slc25a27, Mmus\Ucp3, Mmus\Slc25a14, Mmus\Ucp1, Mmus\Slc25a30, Mmus\Slc25a10, Mmus\Slc25a11" "Hsap\UCP2, Hsap\SLC25A14, Hsap\UCP1, Hsap\UCP3, Hsap\SLC25A30, Hsap\MRPL12, Hsap\SLC25A10, Hsap\SLC25A11, Hsap\SLC25A27" "viable,body color defective" mesothoracic tergum FBgn0028012 l(3)S110013 lethal (3) S110013 http://flybase.org/reports/FBgn0028012 gene - - - "1100/13, l(3)S110013" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0032671 JMJD4 - http://flybase.org/reports/FBgn0032671 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG7200 IPR003347:JmjC domain CG7200 27-Aug-18 DroID_v2018_08 "Drer\jmjd8, Drer\jmjd4" - Cele\jmjd-4 "Xtro\jmjd4, Xtro\jmjd8" "Mmus\Jmjd4, Mmus\Jmjd8" "Hsap\JMJD4, Hsap\JMJD8" viable FBgn0259371 C125 - http://flybase.org/reports/FBgn0259371 gene - - - C125 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing hair,supernumerary,wing" FBgn0011619 l(1)K49c-A7 lethal (1) K49c-A7 http://flybase.org/reports/FBgn0011619 - gene - - - l(1)K49c-A7 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0005479 l(1)ts1107 lethal (1) ts1107 http://flybase.org/reports/FBgn0005479 - gene - - - l(1)ts1107 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,heat sensitive" FBgn0035952 CG5280 - http://flybase.org/reports/FBgn0035952 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG5280 IPR007914:Uncharacterised protein family UPF0193 CG5280 27-Aug-18 DroID_v2018_08 Drer\si:dkey-43k4.3 - - Xtro\c4h22orf23 Mmus\1700088E04Rik Hsap\C22orf23 viable FBgn0040215 fs(3)BQ16 fs(3)BQ16 http://flybase.org/reports/FBgn0040215 gene - - - fs(3)BQ16 - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive" FBgn0026562 SPARC "Secreted protein, acidic, cysteine-rich" http://flybase.org/reports/FBgn0026562 FBgn0027691 protein_coding_gene collagen binding ; GO:0005518 | inferred from biological aspect of ancestor with PANTHER:PTN001015480 calcium ion binding ; GO:0005509 | inferred from biological aspect of ancestor with PANTHER:PTN001015480 extracellular matrix binding ; GO:0050840 | inferred from biological aspect of ancestor with PANTHER:PTN001015480 signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR019577 larval fat body development ; GO:0007504 | inferred from mutant phenotype anterior Malpighian tubule development ; GO:0061327 | inferred from mutant phenotype trachea development ; GO:0060438 | inferred from mutant phenotype larval feeding behavior ; GO:0030536 | inferred from mutant phenotype mesoderm development ; GO:0007498 | inferred from expression pattern cell adhesion ; GO:0007155 | inferred from sequence or structural similarity extracellular matrix constituent secretion ; GO:0070278 | inferred from mutant phenotype Malpighian tubule morphogenesis ; GO:0007443 | inferred from mutant phenotype basement membrane assembly ; GO:0070831 | inferred from mutant phenotype proteinaceous extracellular matrix ; GO:0005578 | inferred from electronic annotation with InterPro:IPR019577 extracellular space ; GO:0005615 | colocalizes_with inferred from direct assay proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity "dsparc, BM-40/SPARC, dSPARC, SPARC, CG6378, BM40, CT19876, anon-EST:Posey291, BM-40-SPARC, Sparc, sparc, BM-40 Sparc, dSparc" "IPR001999:Osteonectin-like, conserved site, IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site, IPR019577:SPARC/Testican, calcium-binding domain" CG6378 27-Aug-18 DroID_v2018_08 "Drer\sparcl2, Drer\fstl1b, Drer\sparcl1, Drer\sparc, Drer\fstl4" - Cele\ost-1 Xtro\sparc "Mmus\Fstl5, Mmus\Spock3, Mmus\Spock1, Mmus\Fstl4, Mmus\Fstl1, Mmus\Sparcl1, Mmus\Sparc" "Hsap\FSTL5, Hsap\SPOCK3, Hsap\SPARCL1, Hsap\SPARC, Hsap\SPOCK1, Hsap\SPOCK2, Hsap\FSTL4" "viable,lethal" "embryonic/first instar larval cuticle,presumptive embryonic/larval tracheal system,ventral nerve cord" FBgn0040764 CG13230 - http://flybase.org/reports/FBgn0040764 protein_coding_gene - - - CG13230 - CG13230 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034253 CG10936 - http://flybase.org/reports/FBgn0034253 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - CG10936 IPR000082:SEA domain CG10936 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" FBgn0011869 tRNA:Gly-GCC-1-10 transfer RNA:Glycine-GCC 1-10 http://flybase.org/reports/FBgn0011869 "FBgn0003782, FBgn0050137, FBgn0050214, FBgn0060216" tRNA_gene GGC codon-amino acid adaptor activity ; GO:0033462 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033462 cytosol ; GO:0005829 | inferred by curator from GO:0033462 "AE002787.trna58-GlyGCC, CR30137, tRNA:G:GCC:AE002787-c, CR30214, tRNA:gly3:56EFa, tRNA[Gly-GCC], chr2R.trna42-GlyGCC, tRNA-Gly-GCC-1-10, tRNA:Gly-GCC-1-10, tRNA:G3:56EFa, GGC" - CR30214 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262447 mir-14 mir-14 stem loop http://flybase.org/reports/FBgn0262447 miRNA_gene - "salivary gland cell autophagic cell death ; GO:0035071 | inferred from mutant phenotype negative regulation of programmed cell death ; GO:0043069 | inferred from genetic interaction with Dronc AND inferred from genetic interaction with hid AND inferred from genetic interaction with grim AND inferred from genetic interaction with rpr AND inferred from mutant phenotype regulation of lipid metabolic process ; GO:0019216 | inferred from mutant phenotype response to starvation ; GO:0042594 | inferred from mutant phenotype insulin-like growth factor receptor signaling pathway ; GO:0048009 | inferred from mutant phenotype mRNA catabolic process ; GO:0006402 | inferred from mutant phenotype wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap negative regulation of apoptotic process ; GO:0043066 | traceable author statement regulation of smoothened signaling pathway ; GO:0008589 | inferred from mutant phenotype terminal cell fate specification, open tracheal system ; GO:0035154 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from mutant phenotype" - "miR-14, dme-mir-14, mir-14, 14, MIR-14, CR43013, Mir-14, l(2)k10213, CR33010, mir14, dme-miR-14, miR14" - CR43013 27-Aug-18 DroID_v2018_08 - - - - - - embryonic stage -- adult stage FBgn0001829 l(1)ts120 lethal (1) ts120 http://flybase.org/reports/FBgn0001829 - gene - - - l(1)ts120 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,heat sensitive" FBgn0267301 lncRNA:CR45737 - http://flybase.org/reports/FBgn0267301 non_protein_coding_gene - - - CR45737 - CR45737 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002685 mb minus bar http://flybase.org/reports/FBgn0002685 - gene - - - mb - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive" FBgn0011078 l(1)Q33 lethal (1) Q33 http://flybase.org/reports/FBgn0011078 FBgn0010210 gene - - - l(1)Q33 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0063261 CG31275 - http://flybase.org/reports/FBgn0063261 protein_coding_gene "ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity" microtubule-based movement ; GO:0007018 | inferred from electronic annotation with InterPro:IPR016561 lateral inhibition ; GO:0046331 | inferred from mutant phenotype microtubule-based movement ; GO:0007018 | non-traceable author statement cytoplasmic dynein complex ; GO:0005868 | inferred from electronic annotation with InterPro:IPR016561 dynein complex ; GO:0030286 | inferred from sequence or structural similarity "CG14908, BcDNA:GH08635, CG31275" IPR016561:Dynein light chain roadblock-type 1/2 CG31275 27-Aug-18 DroID_v2018_08 "Drer\dynlrb1, Drer\si:ch211-147k9.8" - Cele\dyrb-1 "Xtro\dynlrb2, Xtro\dynlrb1" "Mmus\Dynlrb1, Mmus\Dynlrb2" "Hsap\DYNLRB1, Hsap\DYNLRB2" "viable,visible" chaeta FBgn0040536 CG12418 - http://flybase.org/reports/FBgn0040536 protein_coding_gene - - - CG12418 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0010461 l(2)00297 lethal (2) 00297 http://flybase.org/reports/FBgn0010461 - gene - - - l(2)00297 - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0011144 l(1)Q220 lethal (1) Q220 http://flybase.org/reports/FBgn0011144 FBgn0010210 gene - - - l(1)Q220 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0264473 lncRNA:CR43881 - http://flybase.org/reports/FBgn0264473 non_protein_coding_gene - - - CR43881 - CR43881 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035850 Atg18a Autophagy-related 18a http://flybase.org/reports/FBgn0035850 protein_coding_gene "phosphatidylinositol-3-phosphate binding ; GO:0032266 | inferred from electronic annotation with InterPro:IPR032911 phosphatidylinositol-3,5-bisphosphate binding ; GO:0080025 | inferred from electronic annotation with InterPro:IPR032911" cellular response to starvation ; GO:0009267 | inferred from mutant phenotype autophagy ; GO:0006914 | inferred from mutant phenotype autophagosome assembly ; GO:0000045 | inferred from mutant phenotype glycophagy ; GO:0061723 | inferred from mutant phenotype negative regulation of phosphatidylinositol 3-kinase signaling ; GO:0014067 | inferred from mutant phenotype regulation of autophagy ; GO:0010506 | inferred from mutant phenotype larval midgut cell programmed cell death ; GO:0035096 | inferred from mutant phenotype larval midgut histolysis ; GO:0035069 | inferred from mutant phenotype defense response to virus ; GO:0051607 | inferred from mutant phenotype regulation of defense response to virus ; GO:0050688 | inferred from mutant phenotype macroautophagy ; GO:0016236 | inferred from mutant phenotype pre-autophagosomal structure ; GO:0000407 | inferred from electronic annotation with InterPro:IPR032911 "ATG18, CG7986, Atg18, atg18, Atg18a, ATG18.1, Atg18A" "IPR017986:WD40-repeat-containing domain, IPR001680:WD40 repeat, IPR015943:WD40/YVTN repeat-like-containing domain, IPR032911:WD repeat domain phosphoinositide-interacting protein 2" CG7986 27-Aug-18 DroID_v2018_08 "Drer\wipi1, Drer\wdr45b, Drer\wipi2, Drer\wdr45, Drer\LOC100332293" "Scer\ATG18, Scer\ATG21, Scer\HSV2" "Cele\atg-18, Cele\epg-6" "Xtro\wipi1, Xtro\wipi2, Xtro\wdr45b" "Mmus\Wdr45, Mmus\Wipi1, Mmus\Wipi2" "Hsap\WIPI1, Hsap\WDR45, Hsap\WDR45B, Hsap\WIPI2" "lethal - all die before end of larval stage,recessive,stress response defective,neuroanatomy defective,decreased cell growth,some die during larval stage,viable,immune response defective" "embryonic/larval midgut,neuromuscular junction,NMJ bouton,embryonic/larval fat body,embryonic/larval salivary gland,somatic clone | third instar larval stage" FBgn0011915 tRNA:Met-CAT-1-1 transfer RNA:Methionine-CAT 1-1 http://flybase.org/reports/FBgn0011915 "FBgn0003807, FBgn0050255, FBgn0060137" tRNA_gene AUG codon-amino acid adaptor activity ; GO:0033436 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033436 cytosol ; GO:0005829 | inferred by curator from GO:0033436 "CR30255, AE002787.trna34-MetCAT, tRNA:M:CAT:AE002787-d, tRNA:met2:48Ba, chr2R.trna16-MetCAT, tRNA-Met[CAU], tRNA-Met-CAT-1-1, tRNA:Met-CAT-1-1, tRNA:M2:48Ba" - CR30255 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0069109 mus315 mutagen-sensitive 315 http://flybase.org/reports/FBgn0069109 gene - - - mus315 - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,chemical sensitive" FBgn0260775 DnaJ-60 DnaJ-like-60 http://flybase.org/reports/FBgn0260775 protein_coding_gene unfolded protein binding ; GO:0051082 | inferred from sequence or structural similarity with ECOGENE:EG10240 protein folding ; GO:0006457 | inferred from sequence or structural similarity with ECOGENE:EG10240 spermatogenesis ; GO:0007283 | inferred from expression pattern membrane ; GO:0016020 | inferred from sequence model "CG42567, DnaJ-60, anon-WO0172774.147, CG12240, DmJ60, DnaJ60" IPR001623:DnaJ domain CG42567 27-Aug-18 DroID_v2018_08 "Drer\dnajc16l, Drer\dnajc4, Drer\dnaja3b, Drer\dnajc24, Drer\dnajc16, Drer\dnaja3a" Scer\MDJ1 "Cele\dnj-4, Cele\dnj-3" "Xtro\dnajc16, Xtro\dnajc4, Xtro\dnajc24" "Mmus\Dnajc24, Mmus\Dnajc16, Mmus\Dnajc4, Mmus\Dnaja3" "Hsap\DNAJA3, Hsap\DNAJC24, Hsap\DNAJC16, Hsap\DNAJC4" FBgn0053415 5SrRNA:CR33415 5SrRNA:CR33415 http://flybase.org/reports/FBgn0053415 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33415, 5SrRNA:CR33415" - CR33415 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001687 l(1)ESHS8 lethal (1) ESHS8 http://flybase.org/reports/FBgn0001687 - gene - - - l(1)ESHS8 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0052596 CG32596 - http://flybase.org/reports/FBgn0052596 protein_coding_gene - - - CG32596 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035986 CG4022 - http://flybase.org/reports/FBgn0035986 protein_coding_gene molecular_function ; GO:0003674 | no biological data available positive regulation of JAK-STAT cascade ; GO:0046427 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available CG4022 "IPR012981:PIH1 domain, IPR011989:Armadillo-like helical" CG4022 27-Aug-18 DroID_v2018_08 Drer\pih1d2 - Cele\F32D8.4 Xtro\pih1d2 Mmus\Pih1d2 Hsap\PIH1D2 "viable,fertile,visible" trichogen cell FBgn0064166 l(3)AP1 lethal (3) AP1 http://flybase.org/reports/FBgn0064166 gene - - - l(3)AP1 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0010331 Sebp344 Secretion enhancer-binding protein 344 http://flybase.org/reports/FBgn0010331 - gene - - - Sebp344 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265932 lncRNA:CR44721 - http://flybase.org/reports/FBgn0265932 non_protein_coding_gene - - - "CR44721, lincRNA.508" - CR44721 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0053251 CG33251 - http://flybase.org/reports/FBgn0053251 protein_coding_gene - - - CG33251 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0023528 CG2924 - http://flybase.org/reports/FBgn0023528 - protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:19248 protein K48-linked ubiquitination ; GO:0070936 | inferred from sequence or structural similarity with HGNC:19248 cellular_component ; GO:0005575 | no biological data available "CG2924, EG:25E8.2, NICE5" "IPR000608:Ubiquitin-conjugating enzyme E2, IPR016135:Ubiquitin-conjugating enzyme/RWD-like" CG2924 27-Aug-18 DroID_v2018_08 "Drer\ube2ql1, Drer\ube2q1, Drer\ube2q2" Scer\CDC34 Cele\ubc-25 "Xtro\ube2q2, Xtro\ube2ql1" "Mmus\Ube2ql1, Mmus\Ube2q2, Mmus\E330021D16Rik, Mmus\Ube2q1" "Hsap\UBE2Q2, Hsap\UBE2Q1, Hsap\UBE2QL1" FBgn0030963 CG7101 - http://flybase.org/reports/FBgn0030963 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - CG7101 "IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG7101 27-Aug-18 DroID_v2018_08 "Drer\zbtb48, Drer\LOC100330321, Drer\gtf3aa, Drer\LOC568955" Scer\PZF1 "Cele\ztf-29, Cele\pqm-1, Cele\F21A9.2, Cele\zag-1, Cele\F10B5.3" "Xtro\znf250, Xtro\zbtb48" Mmus\Gtf3a "Hsap\ZBTB26, Hsap\ZBTB48, Hsap\ZBTB6, Hsap\GTF3A" "viable,fertile" FBgn0001632 l(1)dn11 lethal (1) discs normal 11 http://flybase.org/reports/FBgn0001632 - gene - - - "l(1)d.norm.-11, l(1)dn11" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,some die during larval stage" FBgn0042143 CG18820 - http://flybase.org/reports/FBgn0042143 protein_coding_gene - - - CG18820 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035887 Jon66Cii Jonah 66Cii http://flybase.org/reports/FBgn0035887 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "66C, CG7170, SP165, Jon66C, Jon66Cii, CCG7170" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR033116:Serine proteases, trypsin family, serine active site" CG7170 27-Aug-18 DroID_v2018_08 Drer\masp2 - - - "Mmus\C1s2, Mmus\Cela1, Mmus\C1s1" "Hsap\C1S, Hsap\F9, Hsap\PROC" viable FBgn0263037 CG43332 - http://flybase.org/reports/FBgn0263037 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43332, CG32972, BG:DS01523.2, CG15291" - CG43332 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037354 CG12171 - http://flybase.org/reports/FBgn0037354 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR020904 - - "anon-WO0118547.83, CG12171" "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain, IPR020904:Short-chain dehydrogenase/reductase, conserved site" CG12171 27-Aug-18 DroID_v2018_08 "Drer\decr2, Drer\elovl7a, Drer\elovl5, Drer\hsd17b14, Drer\pecr, Drer\dhrs7, Drer\hsd17b8, Drer\dhrs1, Drer\elovl4a, Drer\elovl8a, Drer\elovl4b, Drer\elovl7b, Drer\elovl1a, Drer\cbr4, Drer\decr1, Drer\elovl8b, Drer\hsdl2, Drer\elovl1b, Drer\zgc:101858, Drer\elovl2, Drer\bdh2, Drer\zgc:113054" "Scer\IRC24, Scer\OAR1, Scer\YIR035C, Scer\SPS19" "Cele\dhs-25, Cele\dhs-9, Cele\Y47G6A.22, Cele\F59E11.2, Cele\dhs-14, Cele\dhs-11, Cele\decr-1.2, Cele\C06E4.3, Cele\F26D2.15, Cele\ZK829.1, Cele\dhs-26, Cele\C33E10.10, Cele\F25D1.5, Cele\F12E12.11, Cele\F28H7.2, Cele\Y47G6A.21, Cele\D1054.8" "Xtro\MGC79752, Xtro\dhrs7, Xtro\elovl1, Xtro\dhrs4, Xtro\cbr4, Xtro\hsdl2, Xtro\elovl5, Xtro\hsd17b14, Xtro\elovl7, Xtro\hsd17b8, Xtro\decr1, Xtro\elovl2, Xtro\pecr, Xtro\MGC147226, Xtro\decr2" "Mmus\Elovl2, Mmus\Dhrs2, Mmus\Elovl7, Mmus\Hsdl2, Mmus\Bdh2, Mmus\Pecr, Mmus\Dhrs1, Mmus\Hsd17b14, Mmus\Elovl5, Mmus\Decr2, Mmus\H2-Ke6, Mmus\Decr1, Mmus\Dhrs7, Mmus\Cbr4, Mmus\Dhrs4, Mmus\Elovl4" "Hsap\DHRS4L2, Hsap\HSDL2, Hsap\ELOVL4, Hsap\ELOVL5, Hsap\PECR, Hsap\HSD17B8, Hsap\DECR2, Hsap\ELOVL7, Hsap\HSD17B14, Hsap\ELOVL2, Hsap\DECR1, Hsap\BDH2, Hsap\CBR4, Hsap\DHRS4, Hsap\DHRS1, Hsap\DHRS2, Hsap\ELOVL1, Hsap\DHRS7" "viable,fertile" FBgn0085232 CG34203 - http://flybase.org/reports/FBgn0085232 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34203 - CG34203 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000438 dfa deformed antennae http://flybase.org/reports/FBgn0000438 - gene - - - dfa - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,female sterile,male fertile,visible" "wing,eye,macrochaeta,antenna,arista,trident" FBgn0036623 CG4729 - http://flybase.org/reports/FBgn0036623 protein_coding_gene "transferase activity, transferring acyl groups ; GO:0016746 | inferred from electronic annotation with InterPro:IPR002123" metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR002123 endomembrane system ; GO:0012505 | inferred from direct assay "CG4729, AGPAT3" "IPR002123:Phospholipid/glycerol acyltransferase, IPR032098:Acyltransferase, C-terminal domain" CG4729 27-Aug-18 DroID_v2018_08 "Drer\lpgat1, Drer\agpat5, Drer\agpat4, Drer\lclat1, Drer\agpat3" "Scer\CST26, Scer\YDR018C" "Cele\bus-18, Cele\acl-11, Cele\acl-8, Cele\acl-9" "Xtro\lclat1, Xtro\agpat5, Xtro\lpgat1, Xtro\agpat4, Xtro\agpat3" "Mmus\Lpgat1, Mmus\Agpat5, Mmus\Agpat3, Mmus\Agpat4, Mmus\Lclat1" "Hsap\AGPAT3, Hsap\LPGAT1, Hsap\AGPAT4, Hsap\AGPAT5, Hsap\LCLAT1" "viable,fertile" FBgn0263479 scaRNA:PsiU2-35.45 small Cajal body-specific RNA : PsiU2-35.45 http://flybase.org/reports/FBgn0263479 snoRNA_gene snRNA pseudouridylation guide activity ; GO:0030565 | inferred from direct assay - Cajal body ; GO:0015030 | inferred from direct assay "scaRNA:PsiU2-35.45, pugU2-35/45, snoRNA:gp210-a" - CR43594 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004783 Ccp84Aa Ccp84Aa http://flybase.org/reports/FBgn0004783 - protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Ccp, cc8, CG2360, BG:DS00004.1, Ccp84Aa, DmelCcp84Aa" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG2360 27-Aug-18 DroID_v2018_08 - - Cele\fbxb-38 - - - viable DRSC12586 K 0.13265466 -0.464154429 0.190789573 0.374079829 1.653664281 -0.886318367 FBgn0004230 l(3)93Bd lethal (3) 93Bd http://flybase.org/reports/FBgn0004230 - gene - - - "l(3)rlr2, rlr2, l(3)93Bd" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0031568 CG10019 - http://flybase.org/reports/FBgn0031568 protein_coding_gene - transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011701 "GH25970, BEST:GH25970, CG10019" "IPR011701:Major facilitator superfamily, IPR015943:WD40/YVTN repeat-like-containing domain, IPR020846:Major facilitator superfamily domain" CG10019 27-Aug-18 DroID_v2018_08 "Drer\slc16a9b, Drer\slc16a9a" "Scer\MCH5, Scer\ESBP6, Scer\MCH4, Scer\MCH2, Scer\ATG22" "Cele\cat-1, Cele\gem-1" Xtro\slc16a9 "Mmus\Slc16a14, Mmus\Slc16a9" "Hsap\SLC16A9, Hsap\SLC16A14" viable FBgn0082631 S(CycE[JP])2.7 S(CycE[JP])2.7 http://flybase.org/reports/FBgn0082631 gene - - - S(CycE[JP])2.7 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0264521 ff19 - http://flybase.org/reports/FBgn0264521 gene - - - ff19 - - 27-Aug-18 DroID_v2018_08 - - - - - - "meiotic cell cycle defective,male" spermatid FBgn0082975 snoRNA:Psi28S-3305b snoRNA:Psi28S-3305b http://flybase.org/reports/FBgn0082975 snoRNA_gene - - - "snoRNA:Psi28S-3305b, psi28s-3305b, CR34622" - CR34622 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033639 CG9003 - http://flybase.org/reports/FBgn0033639 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model response to endoplasmic reticulum stress ; GO:0034976 | inferred from mutant phenotype SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model "CG9003, FBXL2" "IPR001810:F-box domain, IPR006553:Leucine-rich repeat, cysteine-containing subtype, IPR032675:Leucine-rich repeat domain, L domain-like, IPR001611:Leucine-rich repeat" CG9003 27-Aug-18 DroID_v2018_08 "Drer\fbxl2, Drer\fbxl20, Drer\si:ch73-290k24.5, Drer\fbxl13, Drer\fbxl7, Drer\si:dkey-192l18.9" "Scer\RAD7, Scer\GRR1, Scer\AMN1" "Cele\fbxl-1, Cele\F07A11.4, Cele\EEED8.10" Xtro\fbxl20 "Mmus\Fbxl20, Mmus\Fbxl17, Mmus\Fbxl2, Mmus\Fbxl7, Mmus\Fbxl13" "Hsap\FBXL20, Hsap\FBXL7, Hsap\FBXL13, Hsap\FBXL17, Hsap\FBXL2" viable FBgn0259550 GG01430 - http://flybase.org/reports/FBgn0259550 gene - - - GG01430 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing,anterior crossvein,tarsal segment,unguis,leg" FBgn0266183 lncRNA:CR44889 - http://flybase.org/reports/FBgn0266183 non_protein_coding_gene - - - CR44889 - CR44889 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032244 RfC3 Replication factor C subunit 3 http://flybase.org/reports/FBgn0032244 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959 DNA clamp loader activity ; GO:0003689 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000186208 DNA clamp loader activity ; GO:0003689 | contributes_to inferred from sequence or structural similarity with SGD:S000005234 leading strand elongation ; GO:0006272 | inferred from sequence or structural similarity with SGD:S000005234 sister chromatid cohesion ; GO:0007062 | inferred from sequence or structural similarity with SGD:S000005234 lateral inhibition ; GO:0046331 | inferred from mutant phenotype DNA-dependent DNA replication ; GO:0006261 | inferred from biological aspect of ancestor with PANTHER:PTN000186208 neurogenesis ; GO:0022008 | inferred from mutant phenotype DNA replication factor C complex ; GO:0005663 | inferred from sequence or structural similarity with SGD:S000005234 Elg1 RFC-like complex ; GO:0031391 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay DNA replication factor C complex ; GO:0005663 | inferred from biological aspect of ancestor with PANTHER:PTN000186208 "CG5313, RfC3, DRFC, Rfc3, DmRFC3" "IPR003593:AAA+ ATPase domain, IPR003959:ATPase, AAA-type, core, IPR008921:DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal, IPR013748:Replication factor C, C-terminal, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG5313 27-Aug-18 DroID_v2018_08 "Drer\rfc5, Drer\rfc2" "Scer\CTF18, Scer\RFC3" "Cele\rfc-2, Cele\rfc-4, Cele\F44B9.8" "Xtro\rfc4, Xtro\rfc5, Xtro\rfc2" "Mmus\Rfc4, Mmus\Rfc2, Mmus\Rfc5" "Hsap\RFC2, Hsap\RFC5" "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,chaeta,trichogen cell" FBgn0032708 CG15166 - http://flybase.org/reports/FBgn0032708 protein_coding_gene - - - CG15166 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0052205 hpRNA:CR32205 - http://flybase.org/reports/FBgn0052205 pseudogene_attribute - - - "BcDNA:RE73739, CR32205, hp-CR32205" - CR32205 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0016931 smi45E smell impaired 45E http://flybase.org/reports/FBgn0016931 - gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - smi45E - - 27-Aug-18 DroID_v2018_08 - - - - - - "smell perception defective,behavior defective,recessive" FBgn0003258 rm rimy http://flybase.org/reports/FBgn0003258 - gene - - - rm - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile,eye color defective,recessive,visible" "eye,wing" FBgn0022227 l(2)k03110 lethal (2) k03110 http://flybase.org/reports/FBgn0022227 FBgn0022243 gene - - - "l(2)k02203, l(2)k03110" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" imaginal disc FBgn0028269 l(1)G0437 lethal (1) G0437 http://flybase.org/reports/FBgn0028269 gene - - - l(1)G0437 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0022333 f7 f7 http://flybase.org/reports/FBgn0022333 - gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available f7 - - 27-Aug-18 DroID_v2018_08 - - - - - - "meiotic cell cycle defective,cytokinesis defective,male,recessive" "spermatocyte,primary spermatocyte cyst,onion stage spermatid,spermatozoon" FBgn0032115 CG4438 - http://flybase.org/reports/FBgn0032115 protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:14634 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG4438 "IPR019380:Casein kinase substrate, phosphoprotein PP28" CG4438 27-Aug-18 DroID_v2018_08 "Drer\pdap1a, Drer\pdap1b" - - Xtro\pdap1 Mmus\Pdap1 Hsap\PDAP1 viable FBgn0000449 dib disembodied http://flybase.org/reports/FBgn0000449 FBgn0035492 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 ecdysteroid 22-hydroxylase activity ; GO:0042767 | inferred from direct assay electron carrier activity ; GO:0009055 | inferred from sequence or structural similarity" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 midgut development ; GO:0007494 | inferred from mutant phenotype dorsal closure ; GO:0007391 | traceable author statement chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | inferred from mutant phenotype ecdysone biosynthetic process ; GO:0006697 | inferred from direct assay dorsal closure ; GO:0007391 | inferred from mutant phenotype ecdysone biosynthetic process ; GO:0006697 | inferred from mutant phenotype head involution ; GO:0008258 | inferred from mutant phenotype central nervous system development ; GO:0007417 | inferred from mutant phenotype" mitochondrion ; GO:0005739 | inferred from sequence or structural similarity mitochondrion ; GO:0005739 | inferred from direct assay "Cyp302a1, CYP302A1, 302a1, CG12028, l(3)dib, l(3)SH14, l(3)64Ak, dib, Dib, Cyp" "IPR017972:Cytochrome P450, conserved site, IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I" CG12028 27-Aug-18 DroID_v2018_08 "Drer\cyp27b1, Drer\si:dkey-91i10.3, Drer\cyp27c1, Drer\si:ch211-113j14.1, Drer\cyp27a1.4, Drer\zgc:136333, Drer\cyp27a7, Drer\cyp24a1, Drer\cyp11a2, Drer\cyp11c1, Drer\cyp27a1.2" Scer\DIT2 "Cele\cyp-35B3, Cele\cyp-35A5, Cele\cyp-33D1, Cele\cyp-35A3, Cele\cyp-35C1, Cele\cyp-44A1" "Xtro\cyp27b1, Xtro\cyp27a1, Xtro\cyp27c1, Xtro\LOC100145331, Xtro\cyp11a1, Xtro\cyp24a1" "Mmus\Cyp27b1, Mmus\Cyp11b2, Mmus\Cyp11b1, Mmus\Cyp11a1, Mmus\Cyp24a1, Mmus\Cyp27a1" "Hsap\CYP11B1, Hsap\CYP11B2, Hsap\CYP11A1, Hsap\CYP27B1, Hsap\CYP27A1, Hsap\CYP27C1, Hsap\CYP24A1" " embryonic stage | early , oogenesis stage | stage S8-11 && adult stage | female , embryonic stage | extended germ band , larval stage | third instar , embryonic stage | stage 14-17 " "

anterior , follicle cell

, embryonic epidermis

, ring gland && prothoracic segment

, ring gland && embryonic prothoracic segment

, organism | striped & posterior

" "viable,fertile,wild-type,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,lethal,memory defective,RU486 conditional,large body,developmental rate defective" "presumptive embryonic/larval central nervous system,dorsal closure embryo,stage 14 embryo,midgut primordium,hindgut proper primordium,midgut constriction,yolk granule,embryonic/first instar larval cuticle,denticle belt,dorsal hair,cephalopharyngeal skeleton,embryonic ventral epidermis,ventral nerve cord,embryonic/larval midgut,embryonic/larval foregut,embryonic/larval hindgut,commissure,longitudinal connective,glial cell,midline glial cell,ectopic,embryonic head,pupa,mouth hooks" FBgn0000844 fs(1)M31 female sterile (1) M31 http://flybase.org/reports/FBgn0000844 - gene - - - fs(1)M31 - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive,lethal,maternal effect" FBgn0025720 Ate1 Ate1 http://flybase.org/reports/FBgn0025720 FBgn0021941 protein_coding_gene arginyltransferase activity ; GO:0004057 | inferred from biological aspect of ancestor with PANTHER:PTN000482991 protein arginylation ; GO:0016598 | inferred from biological aspect of ancestor with PANTHER:PTN000482991 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000482991 "Ate, CG9204, ATE1, ate1, Dm-Ate1, l(2)k10809, Ate1" "IPR007471:Arginine-tRNA-protein transferase, N-terminal, IPR007472:Arginine-tRNA-protein transferase, C-terminal, IPR017137:Arginine-tRNA-protein transferase 1, eukaryotic, IPR030700:Arginine-tRNA-protein transferase, IPR016181:Acyl-CoA N-acyltransferase" CG9204 27-Aug-18 DroID_v2018_08 Drer\ate1 Scer\ATE1 Cele\K07A1.9 Xtro\ate1 Mmus\Ate1 Hsap\ATE1 "lethal,recessive,viable" FBgn0033544 CG7220 - http://flybase.org/reports/FBgn0033544 protein_coding_gene ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with MGI:MGI:1914049 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN000630458 protein polyubiquitination ; GO:0000209 | inferred from biological aspect of ancestor with PANTHER:PTN000630458 protein monoubiquitination ; GO:0006513 | inferred from sequence or structural similarity with MGI:MGI:1914049 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000629506 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000630458 "BEST:GH28095, BcDNA:GH28095, CG7220, Ube2W" "IPR000608:Ubiquitin-conjugating enzyme E2, IPR016135:Ubiquitin-conjugating enzyme/RWD-like" CG7220 27-Aug-18 DroID_v2018_08 "Drer\ube2w, Drer\impad1, Drer\flj11011l" Scer\UBC4 "Cele\ubc-16, Cele\gpap-1" "Xtro\ube2w, Xtro\impad1" "Mmus\Impad1, Mmus\Ube2w" "Hsap\IMPAD1, Hsap\UBE2W" "lethal,viable" FBgn0033972 Ciao1 Ciao1 http://flybase.org/reports/FBgn0033972 protein_coding_gene molecular_function ; GO:0003674 | no biological data available neurogenesis ; GO:0022008 | inferred from mutant phenotype iron-sulfur cluster assembly ; GO:0016226 | inferred from sequence or structural similarity with UniProtKB:O76071 iron-sulfur cluster assembly ; GO:0016226 | inferred from biological aspect of ancestor with PANTHER:PTN000460364 CIA complex ; GO:0097361 | inferred from biological aspect of ancestor with PANTHER:PTN000460364 "CG12797, Ciao1, CiaO1" "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat, IPR028608:Probable cytosolic iron-sulfur protein assembly protein, CIAO1/Cia1" CG12797 27-Aug-18 DroID_v2018_08 "Drer\nif3l1, Drer\ciao1" Scer\CIA1 Cele\Y18D10A.9 "Xtro\nif3l1, Xtro\ciao1" "Mmus\Ciao1, Mmus\Nif3l1" Hsap\CIAO1 "viable,fertile,lethal,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0034885 Eglp4 Entomoglyceroporin 4 http://flybase.org/reports/FBgn0034885 protein_coding_gene channel activity ; GO:0015267 | inferred from sequence or structural similarity with Drip water channel activity ; GO:0015250 | inferred from biological aspect of ancestor with PANTHER:PTN000440615 transmembrane transport ; GO:0055085 | inferred from sequence or structural similarity with Drip renal system process ; GO:0003014 | inferred from expression pattern ion transmembrane transport ; GO:0034220 | inferred from biological aspect of ancestor with PANTHER:PTN000440615 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with Drip integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000440615 "CG4019, Aqp4019, Eglp4, Eglp 4" "IPR000425:Major intrinsic protein, IPR034294:Aquaporin transporter, IPR022357:Major intrinsic protein, conserved site, IPR023271:Aquaporin-like" CG4019 27-Aug-18 DroID_v2018_08 "Drer\aqp1a.2, Drer\aqp9b, Drer\aqp3a, Drer\aqp8b, Drer\aqp8a.1, Drer\mipb, Drer\mipa, Drer\aqp7, Drer\aqp10a, Drer\aqp8a.2, Drer\aqp1a.1, Drer\aqp4" "Scer\AQY1, Scer\AQY2, Scer\FPS1, Scer\YLL053C, Scer\YFL054C" "Cele\aqp-6, Cele\aqp-5, Cele\aqp-8, Cele\aqp-4, Cele\aqp-7, Cele\aqp-2, Cele\aqp-3" "Xtro\mip, Xtro\LOC100216133, Xtro\aqp5, Xtro\aqp2" "Mmus\Aqp7, Mmus\Aqp8, Mmus\Aqp4, Mmus\Aqp6, Mmus\Aqp3, Mmus\Aqp9, Mmus\Mip, Mmus\Aqp2, Mmus\Aqp5, Mmus\Aqp1" "Hsap\AQP4, Hsap\AQP5, Hsap\AQP9, Hsap\AQP2, Hsap\MIP, Hsap\AQP8, Hsap\AQP10, Hsap\AQP3, Hsap\AQP1, Hsap\AQP6, Hsap\AQP7" "viable,lethal" FBgn0051198 CG31198 - http://flybase.org/reports/FBgn0051198 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 metalloaminopeptidase activity ; GO:0070006 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 peptide binding ; GO:0042277 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 peptide catabolic process ; GO:0043171 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000164249 "CG5845, anon-WO0140519.12, anon-WO0140519.24, CG31198" "IPR024571:ERAP1-like C-terminal domain, IPR001930:Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase, IPR014782:Peptidase M1, membrane alanine aminopeptidase, N-terminal, IPR034016:Aminopeptidase N-type" CG31198 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-198g19.1, Drer\si:ch211-276a23.5, Drer\ctrl, Drer\enpep, Drer\si:ch211-106j24.1, Drer\erap2, Drer\anpepb, Drer\erap1b, Drer\si:ch211-149p5.1, Drer\anpepa, Drer\lnpep, Drer\npepps, Drer\erap1a" "Scer\APE2, Scer\AAP1, Scer\TMA108" "Cele\mnp-1, Cele\T12E12.6, Cele\R03G8.6, Cele\AC3.5, Cele\Y67D8C.9, Cele\VB0395L.1, Cele\Y53F4B.20, Cele\Y42A5A.1, Cele\F49B2.6, Cele\T16G12.1, Cele\pam-1, Cele\T07F10.1, Cele\R03G8.4" "Xtro\erap1, Xtro\npepps, Xtro\lvrn, Xtro\anpep, Xtro\enpep, Xtro\lnpep" "Mmus\Erap1, Mmus\Enpep, Mmus\Lvrn, Mmus\Anpep, Mmus\Lnpep, Mmus\Npepps, Mmus\Trhde, Mmus\Rnpep" "Hsap\TRHDE, Hsap\LVRN, Hsap\ENPEP, Hsap\ANPEP, Hsap\NPEPPS, Hsap\RNPEP, Hsap\ERAP2, Hsap\ERAP1, Hsap\LNPEP" viable FBgn0036622 CG4753 - http://flybase.org/reports/FBgn0036622 protein_coding_gene "transferase activity, transferring acyl groups ; GO:0016746 | inferred from electronic annotation with InterPro:IPR002123" metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR002123 - "CG4753, AGPAT4" "IPR002123:Phospholipid/glycerol acyltransferase, IPR032098:Acyltransferase, C-terminal domain" CG4753 27-Aug-18 DroID_v2018_08 "Drer\agpat3, Drer\lpgat1, Drer\agpat5, Drer\lclat1, Drer\agpat4" "Scer\YDR018C, Scer\CST26" "Cele\acl-11, Cele\acl-8, Cele\acl-9, Cele\bus-18" "Xtro\lclat1, Xtro\lpgat1, Xtro\agpat5, Xtro\agpat3, Xtro\agpat4" "Mmus\Lpgat1, Mmus\Agpat5, Mmus\Agpat3, Mmus\Lclat1, Mmus\Agpat4" "Hsap\LCLAT1, Hsap\LPGAT1, Hsap\AGPAT3, Hsap\AGPAT4, Hsap\AGPAT5" "viable,fertile" FBgn0028981 tRNA:Ser-CGA-1-4 transfer RNA:Serine-CGA 1-4 http://flybase.org/reports/FBgn0028981 tRNA_gene triplet codon-amino acid adaptor activity ; GO:0030533 | non-traceable author statement UCG codon-amino acid adaptor activity ; GO:0033408 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033408 cytosol ; GO:0005829 | inferred by curator from GO:0033408 "CR30224, tRNA(4Ser), EST E, 444-3, tRNA[Ser][[4]], tRNA[Ser], Ser tRNA[Ser], AE002787.trna50-SerCGA, tRNA:S:CGA:AE002787, tRNA:ser, tRNA:S, tRNA:ser4, tRNA:S4, tRNA:S4:64D, tRNA:ser4:64D, tRNA[[Ser]], chr2R.trna33-SerCGA, tRNA-Ser-CGA-1-4, tRNA:Ser-CGA-1-4, tRNA:S4:56D, UCG" - CR30224 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0069065 5SrRNA-Psi 5S ribosomal RNA pseudogene http://flybase.org/reports/FBgn0069065 pseudogene_attribute - - - 5SrRNA-Psi - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267280 CR45716 - http://flybase.org/reports/FBgn0267280 pseudogene_attribute - - - CR45716 - CR45716 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0011769 Fdx1 Ferredoxin 1 http://flybase.org/reports/FBgn0011769 FBgn0062914 protein_coding_gene "electron carrier activity ; GO:0009055 | inferred from sequence or structural similarity with HGNC:3638 2 iron, 2 sulfur cluster binding ; GO:0051537 | inferred from sequence or structural similarity with HGNC:3638" pupariation ; GO:0035073 | inferred from mutant phenotype positive regulation of ecdysteroid biosynthetic process ; GO:0045998 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with HGNC:3638 "CG4205, BcDNA:RH67819, Fdx1, Fdxh" "IPR018298:Adrenodoxin, iron-sulphur binding site, IPR001041:2Fe-2S ferredoxin-type iron-sulfur binding domain, IPR001055:Adrenodoxin, IPR012675:Beta-grasp domain" CG4205 27-Aug-18 DroID_v2018_08 "Drer\fdx1b, Drer\fdx1l, Drer\fdx1, Drer\cox15" "Scer\COX15, Scer\YAH1" "Cele\Y73F8A.27, Cele\cox-15" "Xtro\fdx1l, Xtro\fdx1" "Mmus\Fdx1l, Mmus\Fdx1, Mmus\Cox15" "Hsap\FDX1, Hsap\FDX1L, Hsap\COX15" viable FBgn0052647 CG32647 - http://flybase.org/reports/FBgn0052647 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CT35953, CG15723, CG3794, CG18453, BcDNA:RH40632, CG32647" - CG32647 27-Aug-18 DroID_v2018_08 Drer\dgcr2 - - Xtro\dgcr2 Mmus\Dgcr2 Hsap\DGCR2 "viable,fertile" FBgn0060674 l(3)S077515 lethal (3) S077515 http://flybase.org/reports/FBgn0060674 gene - - - "0775/15, l(3)S077515" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0013491 l(1)8PP9 lethal (1) 8PP9 http://flybase.org/reports/FBgn0013491 - gene - - - l(1)8PP9 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,germline clone,maternal effect" "embryo,germline clone,embryonic/first instar larval cuticle" FBgn0065947 l(2)SH0100 lethal (2) SH0100 http://flybase.org/reports/FBgn0065947 gene - - - "l(2)SH0100, l(2)SH2 0100" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0034058 Pex11 Peroxin 11 http://flybase.org/reports/FBgn0034058 protein_coding_gene - "regulation of peroxisome size ; GO:0044375 | inferred from biological aspect of ancestor with PANTHER:PTN000291586 peroxisome organization ; GO:0007031 | inferred from mutant phenotype peroxisome organization ; GO:0007031 | inferred from sequence or structural similarity with HGNC:8852,HGNC:8853 peroxisome fission ; GO:0016559 | inferred from biological aspect of ancestor with PANTHER:PTN000291586" "integral component of peroxisomal membrane ; GO:0005779 | inferred from electronic annotation with InterPro:IPR008733 peroxisomal membrane ; GO:0005778 | inferred from biological aspect of ancestor with PANTHER:PTN000291586 peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:8852,HGNC:8853" "CG8315, Pex11, DmelPex11, PEX11A, PEX11B" IPR008733:Peroxisomal biogenesis factor 11 CG8315 27-Aug-18 DroID_v2018_08 "Drer\pex11g, Drer\pex11b, Drer\pex11a" Scer\PEX11 Cele\prx-11 "Xtro\pex11b, Xtro\pex11a, Xtro\pex11g" "Mmus\Itga10, Mmus\Pex11b, Mmus\Pex11a, Mmus\Pex11g" "Hsap\PEX11A, Hsap\PEX11G, Hsap\PEX11B" "viable,fertile" FBgn0034103 prim primacord http://flybase.org/reports/FBgn0034103 protein_coding_gene - detection of temperature stimulus involved in sensory perception of pain ; GO:0050965 | inferred from mutant phenotype - "BcDNA:RH57845, prim, CG15704" - CG15704 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038596 CG14312 - http://flybase.org/reports/FBgn0038596 protein_coding_gene - - - CG14312 - CG14312 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0259427 EP-149 - http://flybase.org/reports/FBgn0259427 gene - - - EP-149 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible wing FBgn0065266 l(2)SH2068 lethal (2) SH2068 http://flybase.org/reports/FBgn0065266 gene - - - l(2)SH2068 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0034850 CG9875 - http://flybase.org/reports/FBgn0034850 protein_coding_gene - - - "BcDNA:GH23338, CG9875" - CG9875 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0005231 l(3)R18 lethal of Roberts 18 http://flybase.org/reports/FBgn0005231 - gene - - - "l(3)B18, l(3)R18" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,polyphasic,recessive" FBgn0035543 CG15020 - http://flybase.org/reports/FBgn0035543 protein_coding_gene structural constituent of chitin-based cuticle ; GO:0005214 | inferred from sequence or structural similarity with dy cell morphogenesis ; GO:0000902 | inferred from sequence or structural similarity with dyl integral component of membrane ; GO:0016021 | inferred from sequence model CG15020 IPR001507:Zona pellucida domain CG15020 27-Aug-18 DroID_v2018_08 "Drer\zmp:0000001031, Drer\si:ch211-229d2.5, Drer\zgc:153932, Drer\si:ch211-103f14.3" - "Cele\cut-5, Cele\cutl-5, Cele\cutl-19, Cele\cutl-2, Cele\cutl-8, Cele\cutl-14, Cele\T01D1.8, Cele\cutl-18, Cele\cutl-11, Cele\cutl-24, Cele\F46G11.6, Cele\cutl-9, Cele\cutl-28, Cele\cut-1, Cele\cutl-29, Cele\cutl-15, Cele\cut-4, Cele\cutl-1, Cele\cutl-22, Cele\cutl-16, Cele\cutl-25, Cele\ram-5, Cele\cutl-4, Cele\cutl-13, Cele\cutl-3, Cele\cutl-12, Cele\cutl-7, Cele\cutl-20, Cele\cut-3, Cele\cutl-6, Cele\dpy-1, Cele\cut-6, Cele\cutl-10, Cele\cutl-26" "Xtro\thdl18, Xtro\MGC89178, Xtro\thdl17" - - "viable,fertile" FBgn0265695 lncRNA:CR44502 - http://flybase.org/reports/FBgn0265695 non_protein_coding_gene - - - CR44502 - CR44502 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260743 GC1 Glutamate Carrier 1 http://flybase.org/reports/FBgn0260743 protein_coding_gene high-affinity glutamate transmembrane transporter activity ; GO:0005314 | inferred from direct assay transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR002067 L-glutamate transport ; GO:0015813 | inferred from mutant phenotype mitochondrial transport ; GO:0006839 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 mitochondrial inner membrane ; GO:0005743 | inferred from biological aspect of ancestor with PANTHER:PTN000640304 mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with MGI:MGI:1919053 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000211803 "CG18347, 87A7-9/4, anon-87Ac, DmGC1, GC1" "IPR018108:Mitochondrial substrate/solute carrier, IPR002067:Mitochondrial carrier protein, IPR023395:Mitochondrial carrier domain" CG18347 27-Aug-18 DroID_v2018_08 "Drer\slc25a22, Drer\si:ch73-219d10.1, Drer\slc25a12, Drer\slc25a18, Drer\si:dkey-201c1.2, Drer\zgc:92113" "Scer\GGC1, Scer\AGC1" "Cele\F55G1.5, Cele\F20D1.9, Cele\K02F3.2" "Xtro\slc25a22, Xtro\slc25a13, Xtro\slc25a18, Xtro\slc25a12" "Mmus\Slc25a12, Mmus\Slc25a18, Mmus\Slc25a22, Mmus\Slc25a13" "Hsap\SLC25A13, Hsap\SLC25A12, Hsap\SLC25A18, Hsap\SLC25A22" FBgn0004944 agq atrophie gonadique http://flybase.org/reports/FBgn0004944 - gene - - - agq - - 27-Aug-18 DroID_v2018_08 - - - - - - "grandchildless,heat sensitive" "pole cell,heat sensitive,gonad" FBgn0062560 P42 P42 http://flybase.org/reports/FBgn0062560 gene - - - P42 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262362 CG43060 - http://flybase.org/reports/FBgn0262362 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43060 - CG43060 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039789 CG9717 - http://flybase.org/reports/FBgn0039789 protein_coding_gene secondary active sulfate transmembrane transporter activity ; GO:0008271 | inferred from electronic annotation with InterPro:IPR001902 bicarbonate transmembrane transporter activity ; GO:0015106 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 oxalate transmembrane transporter activity ; GO:0019531 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 chloride channel activity ; GO:0005254 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 anion:anion antiporter activity ; GO:0015301 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 sulfate transmembrane transporter activity ; GO:0015116 | inferred from biological aspect of ancestor with PANTHER:PTN000212031 "sulfate transport ; GO:0008272 | inferred from electronic annotation with InterPro:IPR001902, InterPro:IPR011547 chloride transmembrane transport ; GO:1902476 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 regulation of intracellular pH ; GO:0051453 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 bicarbonate transport ; GO:0015701 | inferred from biological aspect of ancestor with PANTHER:PTN000212047 regulation of membrane potential ; GO:0042391 | inferred from biological aspect of ancestor with PANTHER:PTN000212047" integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000212031 CG9717 "IPR002645:STAS domain, IPR011547:SLC26A/SulP transporter domain, IPR001902:SLC26A/SulP transporter" CG9717 27-Aug-18 DroID_v2018_08 "Drer\slc26a3.2, Drer\slc26a11, Drer\slc26a5, Drer\slc26a6l, Drer\slc26a2, Drer\slc26a4, Drer\slc26a3.1, Drer\si:ch211-117c9.2, Drer\slc26a6, Drer\slc26a1, Drer\slc26a10" "Scer\YGR125W, Scer\SUL2, Scer\SUL1, Scer\YPR003C" "Cele\sulp-7, Cele\sulp-2, Cele\sulp-5, Cele\sulp-1, Cele\sulp-4, Cele\sulp-3, Cele\sulp-6, Cele\sulp-8" "Xtro\slc26a2, Xtro\slc26a7, Xtro\slc26a4, Xtro\slc26a6, Xtro\slc26a10, Xtro\slc26a5, Xtro\slc26a1, Xtro\slc26a11, Xtro\slc26a9" "Mmus\Slc26a2, Mmus\Slc26a10, Mmus\Slc26a7, Mmus\Slc26a5, Mmus\Slc26a1, Mmus\Slc26a4, Mmus\Slc26a3, Mmus\Slc26a11, Mmus\Slc26a8, Mmus\Slc26a6, Mmus\Slc26a9" "Hsap\SLC26A8, Hsap\SLC26A5, Hsap\SLC26A10, Hsap\SLC26A3, Hsap\SLC26A11, Hsap\SLC26A6, Hsap\SLC26A4, Hsap\SLC26A9, Hsap\SLC26A1, Hsap\SLC26A7, Hsap\SLC26A2" viable FBgn0004748 l(3)89Ba lethal (3) 89Ba http://flybase.org/reports/FBgn0004748 - gene - - - l(3)89Ba - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0051353 CG31353 - http://flybase.org/reports/FBgn0051353 protein_coding_gene - - - CG31353 - - 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC23083 K 0.109900945 1.529388491 FBgn0051882 CG31882 - http://flybase.org/reports/FBgn0051882 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "bs35a07.y1, NEST:bs35a07, CG31882" - CG31882 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0267537 lncRNA:CR45877 - http://flybase.org/reports/FBgn0267537 non_protein_coding_gene - - - CR45877 - CR45877 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051337 CG31337 - http://flybase.org/reports/FBgn0051337 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE40816, CG31337" "IPR022700:Proteinase, regulatory CLIP domain" CG31337 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0069226 gl(2L)50-27 gl(2L)50-27 http://flybase.org/reports/FBgn0069226 gene molecular_function ; GO:0003674 | no biological data available anterior/posterior pattern specification ; GO:0009952 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available gl(2L)50-27 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,germline clone,non-rescuable maternal effect,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "embryo,germline clone,maternal effect,posterior" FBgn0031233 Tbc1d15-17 TBC1 domain family member 15/17 http://flybase.org/reports/FBgn0031233 protein_coding_gene Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab5 GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with Evi5 GTPase activator activity ; GO:0005096 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 regulation of GTPase activity ; GO:0043087 | inferred from sequence or structural similarity with Evi5 intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 activation of GTPase activity ; GO:0090630 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 regulation of vesicle fusion ; GO:0031338 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 intracellular ; GO:0005622 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 endomembrane system ; GO:0012505 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 "CG11490, Tbc1d15-17" IPR000195:Rab-GTPase-TBC domain CG11490 27-Aug-18 DroID_v2018_08 "Drer\tbc1d15, Drer\tbc1d17, Drer\si:dkey-238d18.4, Drer\tbc1d25" Scer\GYP7 Cele\tbc-14 "Xtro\tbc1d17, Xtro\tbc1d15" "Mmus\Tbc1d17, Mmus\Tbc1d15, Mmus\Tbc1d25, Mmus\Tbc1d21" "Hsap\TBC1D17, Hsap\TBC1D21, Hsap\TBC1D25, Hsap\TBC1D15" "viable,fertile" FBgn0261552 ps pasilla http://flybase.org/reports/FBgn0261552 protein_coding_gene mRNA binding ; GO:0003729 | inferred from sequence or structural similarity with HGNC:7886 inferred from sequence or structural similarity with HGNC:7887 "mRNA splicing, via spliceosome ; GO:0000398 | inferred from expression pattern" nucleus ; GO:0005634 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "ps, PS, NOVA1, CG42670, CG16765, cg8144, EP(3)3406, l(3)10615, CG16776, BcDNA:RE47781, CG18509, CG8144, CG16777" "IPR004087:K Homology domain, IPR004088:K Homology domain, type 1" CG42670 27-Aug-18 DroID_v2018_08 "Drer\nova2, Drer\nova1" Scer\PBP2 Cele\Y59A8B.10 "Xtro\nova2, Xtro\nova1" "Mmus\Nova2, Mmus\Nova1" "Hsap\NOVA1, Hsap\NOVA2" """DRSC16388, DRSC22989"" " IEK FBgn0264448 asRNA:CR43866 - http://flybase.org/reports/FBgn0264448 non_protein_coding_gene - - - CR43866 - CR43866 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039336 CG4553 - http://flybase.org/reports/FBgn0039336 protein_coding_gene - - - CG4553 IPR010487:Neugrin/Rrg9 CG4553 27-Aug-18 DroID_v2018_08 Drer\ngrn - - - Mmus\Ngrn Hsap\NGRN viable FBgn0082358 HM17 HM17 http://flybase.org/reports/FBgn0082358 gene - - - HM17 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267225 lncRNA:CR45665 - http://flybase.org/reports/FBgn0267225 non_protein_coding_gene - - - CR45665 - CR45665 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0082910 60-15 60-15 http://flybase.org/reports/FBgn0082910 gene - - - 60-15 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0023128 anon-10Aaa anon-10Aaa http://flybase.org/reports/FBgn0023128 - gene - - - "20, anon-10Aaa" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0029825 CG12728 - http://flybase.org/reports/FBgn0029825 protein_coding_gene - double-strand break repair ; GO:0006302 | inferred from electronic annotation with InterPro:IPR015381 nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR015381 "CG12728, XRCC4" IPR015381:XLF family CG12728 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0027644 l(3)CL-R lethal (3) Cell Lethal Right http://flybase.org/reports/FBgn0027644 - gene - - - "CL3R, l(3)CL-R" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0262836 CG43200 - http://flybase.org/reports/FBgn0262836 protein_coding_gene - - - "CG43200, nc_5744.a" - CG43200 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0053358 5SrRNA:CR33358 5SrRNA:CR33358 http://flybase.org/reports/FBgn0053358 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33358, 5SrRNA:CR33358" - CR33358 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000008 a arc http://flybase.org/reports/FBgn0000008 "FBgn0034701, FBgn0034702" protein_coding_gene molecular_function ; GO:0003674 | no biological data available bicellular tight junction assembly ; GO:0070830 | inferred from electronic annotation with InterPro:IPR029906 compound eye development ; GO:0048749 | inferred from mutant phenotype apical plasma membrane ; GO:0016324 | inferred from direct assay adherens junction ; GO:0005912 | inferred from direct assay "a, CG13505, Arc, CG6741, bran" "IPR001478:PDZ domain, IPR029906:FERM and PDZ domain-containing protein 2, IPR015943:WD40/YVTN repeat-like-containing domain" CG6741 27-Aug-18 DroID_v2018_08 "Drer\frmpd2, Drer\cox16, Drer\pdzd2, Drer\synj2bp, Drer\il16" - "Cele\mics-1, Cele\pqn-92, Cele\Y75B8A.28, Cele\Y75B8A.39" - "Mmus\Synj2bp, Mmus\Pdzd2, Mmus\Il16, Mmus\Cox16, Mmus\Synj2bp-cox16" "Hsap\PDZD2, Hsap\SYNJ2BP, Hsap\IL16, Hsap\SYNJ2BP-COX16, Hsap\FRMPD2, Hsap\COX16" " embryonic stage , embryonic stage | stage >=6 , larval stage | third instar , embryonic stage | early , embryonic stage | stage >12 , embryonic stage | stage >=10 " " embryonic/larval salivary gland

, posterior midgut proper primordium

, embryonic/larval foregut

, morphogenetic furrow

,

anterior posterior gradient , embryonic/larval hindgut

, Malpighian tubule

" " embryonic stage , embryonic stage | stage >=6 , embryonic stage | stage >13 , embryonic stage | stage >=10 , larval stage | third instar " " embryonic/larval salivary gland

, posterior midgut proper primordium

, embryonic/larval foregut

, embryonic/larval hindgut

, Malpighian tubule

, morphogenetic furrow

" "lethal,visible,dominant,viable,recessive,wild-type,sterile,lethal - all die before end of pupal stage,some die during pupal stage" "wing,eye,ommatidium,posterior scutellar bristle,macrochaeta,crossvein" FBgn0025498 l(3)73Bf lethal (3) 73Bf http://flybase.org/reports/FBgn0025498 - gene - - - l(3)73Bf - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0065665 l(2)SH0701 lethal (2) SH0701 http://flybase.org/reports/FBgn0065665 gene - - - "l(2)SH0701, l(2)SH2 0701" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0265375 lncRNA:CR44316 - http://flybase.org/reports/FBgn0265375 non_protein_coding_gene - - - "CR44316, lincRNA.291" - CR44316 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034828 CG13545 - http://flybase.org/reports/FBgn0034828 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13545 - CG13545 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,some die during pupal stage" FBgn0002096 l(2)57Cb lethal (2) 57Cb http://flybase.org/reports/FBgn0002096 - gene - - - l(2)57Cb - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0016885 l(2)39DEj lethal (2) 39DEj http://flybase.org/reports/FBgn0016885 - gene - - - "D244, l(2)39DEj" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0001897 l(2)21Fc lethal (2) 21Fc http://flybase.org/reports/FBgn0001897 - gene - - - "l(2)neh-11, l(2)neh11, l(2)21Fc" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0265068 asRNA:CR44179 - http://flybase.org/reports/FBgn0265068 non_protein_coding_gene - - - CR44179 - CR44179 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0052075 CG32075 - http://flybase.org/reports/FBgn0052075 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype - "CG6316, CG32075" IPR007174:Las1-like CG32075 27-Aug-18 DroID_v2018_08 Drer\las1l Scer\LAS1 Cele\Y6B3B.9 - Mmus\Las1l Hsap\LAS1L "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0041635 EM3-1 EM3-1 http://flybase.org/reports/FBgn0041635 gene - - - EM3-1 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085413 CG34384 - http://flybase.org/reports/FBgn0085413 protein_coding_gene NAD+ kinase activity ; GO:0003951 | inferred from electronic annotation with InterPro:IPR017438 diacylglycerol kinase activity ; GO:0004143 | inferred from sequence or structural similarity with HGNC:2854 diacylglycerol kinase activity ; GO:0004143 | inferred from sequence or structural similarity with UniProtKB:Q86XP1 diacylglycerol kinase activity ; GO:0004143 | non-traceable author statement metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR017438 intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR002219 protein oligomerization ; GO:0051259 | inferred from sequence or structural similarity with UniProtKB:Q86XP1 phosphorylation ; GO:0016310 | non-traceable author statement protein kinase C-activating G-protein coupled receptor signaling pathway ; GO:0007205 | inferred from sequence or structural similarity with HGNC:2854 protein kinase C-activating G-protein coupled receptor signaling pathway ; GO:0007205 | inferred from sequence or structural similarity with UniProtKB:Q86XP1 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:Q86XP1 endosome ; GO:0005768 | inferred from sequence or structural similarity with UniProtKB:Q86XP1 "CG34384, CG14462, DGKd, CG9851, CG2667, CG31187, dgkd" "IPR000756:Diacylglycerol kinase, accessory domain, IPR016064:NAD kinase/diacylglycerol kinase-like domain, IPR001206:Diacylglycerol kinase, catalytic domain, IPR001849:Pleckstrin homology domain, IPR011993:PH domain-like, IPR013761:Sterile alpha motif/pointed domain, IPR001660:Sterile alpha motif domain, IPR002219:Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, IPR017438:Inorganic polyphosphate/ATP-NAD kinase, domain 1" CG34384 27-Aug-18 DroID_v2018_08 "Drer\dgkh, Drer\si:dkey-172j4.3" - Cele\dgk-4 Xtro\dgkh "Mmus\Dgkd, Mmus\Dgkh, Mmus\Dgkk" "Hsap\DGKD, Hsap\DGKH, Hsap\DGKK" FBgn0032442 CG15485 - http://flybase.org/reports/FBgn0032442 protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR018497" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000718, InterPro:IPR008753, InterPro:IPR018497" - CG15485 "IPR000718:Peptidase M13, IPR008753:Peptidase M13, N-terminal domain, IPR018497:Peptidase M13, C-terminal domain, IPR024079:Metallopeptidase, catalytic domain" CG15485 27-Aug-18 DroID_v2018_08 "Drer\ece2b, Drer\phex, Drer\mmel1, Drer\ece1" - "Cele\nep-26, Cele\nep-12, Cele\nep-17, Cele\nep-18, Cele\nep-6, Cele\nep-16, Cele\nep-10, Cele\nep-5" "Xtro\ece2, Xtro\ece1, Xtro\ecel1, Xtro\mmel1" "Mmus\Mmel1, Mmus\Mme, Mmus\Ece2, Mmus\Phex, Mmus\Kel, Mmus\Ecel1, Mmus\Ece1" "Hsap\ECE1, Hsap\ECEL1, Hsap\KEL, Hsap\PHEX, Hsap\MMEL1, Hsap\MME, Hsap\ECE2" viable FBgn0037225 TwdlG TweedleG http://flybase.org/reports/FBgn0037225 protein_coding_gene structural constituent of chitin-based cuticle ; GO:0005214 | inferred from sequence or structural similarity with TwdlD chitin-based cuticle development ; GO:0040003 | inferred from sequence or structural similarity with TwdlD body morphogenesis ; GO:0010171 | inferred from sequence or structural similarity with TwdlD proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity with TwdlD "TwdlG, CG14643" IPR004145:Domain of unknown function DUF243 CG14643 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0020371 Tim17b2 Translocase inner membrane 17 http://flybase.org/reports/FBgn0020371 "FBgn0032565, FBgn0065011, FBgn0065023" protein_coding_gene protein channel activity ; GO:0015266 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000050380 P-P-bond-hydrolysis-driven protein transmembrane transporter activity ; GO:0015450 | inferred from sequence or structural similarity with UniProtKB:O60830 protein targeting to mitochondrion ; GO:0006626 | inferred from sequence or structural similarity with UniProtKB:O60830 protein import into mitochondrial matrix ; GO:0030150 | inferred from biological aspect of ancestor with PANTHER:PTN000050380 mitochondrial inner membrane presequence translocase complex ; GO:0005744 | inferred from biological aspect of ancestor with PANTHER:PTN000050380 mitochondrial inner membrane presequence translocase complex ; GO:0005744 | inferred from sequence or structural similarity with UniProtKB:O60830 integral component of mitochondrial inner membrane ; GO:0031305 | inferred from biological aspect of ancestor with PANTHER:PTN000050380 mitochondrial inner membrane presequence translocase complex ; GO:0005744 | inferred from sequence or structural similarity "BG:DS01845.2, dmTim17, BcDNA:AT13511, BcDNA:AT05822, Tim17, CG15257, Tim17b2" IPR003397:Mitochondrial inner membrane translocase subunit Tim17/Tim22/Tim23/peroxisomal protein PMP24 CG15257 27-Aug-18 DroID_v2018_08 "Drer\timm17a, Drer\timm17b" Scer\TIM17 "Cele\D2096.1, Cele\E04A4.5" Xtro\timm17a "Mmus\Timm17a, Mmus\Timm17b" "Hsap\TIMM17B, Hsap\TIMM17A" viable FBgn0010770 ppan peter pan http://flybase.org/reports/FBgn0010770 "FBgn0011392, FBgn0026381" protein_coding_gene rRNA binding ; GO:0019843 | inferred from biological aspect of ancestor with PANTHER:PTN000292112 imaginal disc development ; GO:0007444 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype larval development ; GO:0002164 | inferred from mutant phenotype female gamete generation ; GO:0007292 | inferred from mutant phenotype ribosomal large subunit assembly ; GO:0000027 | inferred from biological aspect of ancestor with PANTHER:PTN000292112 "preribosome, large subunit precursor ; GO:0030687 | inferred from biological aspect of ancestor with PANTHER:PTN000292112" "l(3)02231, l(3)j6B6, CG5786, ppan, Ppan, PPAN" IPR007109:Brix domain CG5786 27-Aug-18 DroID_v2018_08 "Drer\p2ry11, Drer\ppan" "Scer\SSF2, Scer\SSF1" Cele\lpd-6 Xtro\ppan Mmus\Ppan "Hsap\PPAN-P2RY11, Hsap\PPAN, Hsap\P2RY11" " embryonic stage , adult stage && oogenesis stage "

ubiquitous "lethal,polyphasic,recessive,wild-type,visible,increased cell death,neuroanatomy defective,partially lethal - majority die,some die during pupal stage" "eye,somatic clone,adult cuticle,wing margin bristle,egg,nurse cell,oocyte,wing,wing vein,posterior,wing disc,dorsal,wing hair & wing | dorsalBx-MS1096,embryonic/larval neuroblast,ganglion mother cell,mesothoracic tergum" DRSC17030 E 0.012365267 0.429085793 -2.129446907 -0.065422564 -0.421742788 -0.527329521 FBgn0035332 CG13801 - http://flybase.org/reports/FBgn0035332 protein_coding_gene - transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR004680 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR004680 CG13801 IPR004680:Citrate transporter-like domain CG13801 27-Aug-18 DroID_v2018_08 Drer\oca2 - Cele\srh-98 Xtro\oca2 Mmus\Oca2 Hsap\OCA2 FBgn0030850 stas Stasimon http://flybase.org/reports/FBgn0030850 protein_coding_gene - "positive regulation of synaptic transmission, cholinergic ; GO:0032224 | inferred from mutant phenotype" - "CG8408, stas, Tmem41b" "IPR032816:SNARE associated Golgi protein, IPR015943:WD40/YVTN repeat-like-containing domain" CG8408 27-Aug-18 DroID_v2018_08 "Drer\tmem41b, Drer\tmem41aa, Drer\tmem41ab, Drer\tmem64" Scer\TVP38 "Cele\tag-175, Cele\bus-19, Cele\Y71A12C.2" Xtro\tmem41b "Mmus\Tmem41a, Mmus\Tmem64, Mmus\Tmem41b" "Hsap\TMEM64, Hsap\TMEM41A, Hsap\TMEM41B" "viable,neurophysiology defective" "embryonic/larval neuromuscular junction | larval stage,embryonic/larval neuromuscular junction" FBgn0022221 l(2)k03303 lethal (2) k03303 http://flybase.org/reports/FBgn0022221 - gene - - - l(2)k03303 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0260092 2L2769 - http://flybase.org/reports/FBgn0260092 gene - - - 2L2769 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" "embryonic/larval dorsal trunk,somatic clone" FBgn0267582 lncRNA:CR45922 - http://flybase.org/reports/FBgn0267582 non_protein_coding_gene - - - CR45922 - CR45922 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037801 CG3999 - http://flybase.org/reports/FBgn0037801 protein_coding_gene "glycine dehydrogenase (decarboxylating) activity ; GO:0004375 | inferred from electronic annotation with InterPro:IPR003437, InterPro:IPR020581" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR003437, InterPro:IPR020580, InterPro:IPR020581 glycine catabolic process ; GO:0006546 | inferred from electronic annotation with InterPro:IPR020580, InterPro:IPR020581" mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000206533 CG3999 "IPR003437:Glycine dehydrogenase (decarboxylating), IPR015421:Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015424:Pyridoxal phosphate-dependent transferase, IPR020581:Glycine cleavage system P protein, IPR015422:Pyridoxal phosphate-dependent transferase, subdomain 2" CG3999 27-Aug-18 DroID_v2018_08 Drer\gldc Scer\GCV2 Cele\R12C12.1 Xtro\gldc Mmus\Gldc Hsap\GLDC partially lethal - majority die FBgn0003439 smaller-eye smaller eye http://flybase.org/reports/FBgn0003439 - gene - - - "smaller-eye, sme" - - 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,viable,male,reduced,visible,eye color defective" "pigment cell,eye,wing" FBgn0037426 CG18394 - http://flybase.org/reports/FBgn0037426 protein_coding_gene - - - CG18394 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0026339 Su(tor)2-28-23 Su(tor)2-28-23 http://flybase.org/reports/FBgn0026339 - gene - - - Su(tor)2-28-23 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0020593 anon-57Cd anon-57Cd http://flybase.org/reports/FBgn0020593 - gene - - - anon-57Cd - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0050339 CG30339 - http://flybase.org/reports/FBgn0050339 protein_coding_gene transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR001071 transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR001071 intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR001071 "BcDNA:RE54230, CG30339" "IPR001071:Cellular retinaldehyde binding/alpha-tocopherol transport, IPR001251:CRAL-TRIO lipid binding domain, IPR011074:CRAL/TRIO, N-terminal domain" CG30339 27-Aug-18 DroID_v2018_08 "Drer\rlbp1b, Drer\rlbp1a, Drer\sec14l8, Drer\sec14l7, Drer\clvs2, Drer\ttpal, Drer\ttpa" "Scer\SFH5, Scer\YKL091C, Scer\SEC14" - "Xtro\sec14l3, Xtro\ttpal, Xtro\sec14l5, Xtro\clvs1, Xtro\rlbp1, Xtro\mospd2, Xtro\clvs2, Xtro\ttpa, Xtro\sec14l1" "Mmus\Ttpal, Mmus\Clvs2, Mmus\Sec14l5, Mmus\Sec14l2, Mmus\Rlbp1, Mmus\Ttpa, Mmus\Clvs1, Mmus\Sec14l1, Mmus\Sec14l4, Mmus\Sec14l3" "Hsap\CLVS1, Hsap\SEC14L1, Hsap\CLVS2, Hsap\SEC14L5, Hsap\SEC14L4, Hsap\SEC14L6, Hsap\RLBP1, Hsap\SEC14L3, Hsap\SEC14L2, Hsap\TTPA, Hsap\TTPAL" FBgn0004747 l(3)85Fd lethal (3) 85Fd http://flybase.org/reports/FBgn0004747 - gene - - - l(3)85Fd - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0014105 anon-4Cd anon-4Cd http://flybase.org/reports/FBgn0014105 - gene - - - "T8a,b, anon-4Cd" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001668 l(1)EN4 lethal (1) from Eugene Nonautonomous 4 http://flybase.org/reports/FBgn0001668 - gene - - - l(1)EN4 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0084170 Abd-B-PTS6 Abdominal B promoter targeting sequence 6 http://flybase.org/reports/FBgn0084170 regulatory_region - - - "PTS-6, Abd-B-PTS6" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0278603 Scr::Mmus\Hoxa5 - http://flybase.org/reports/FBgn0278603 engineered_fusion_gene - - - Scr::Mmus\Hoxa5 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0003404 Si Ski http://flybase.org/reports/FBgn0003404 - gene - - - Si - - 27-Aug-18 DroID_v2018_08 - - - - - - wild-type FBgn0027603 Ulp1 Ulp1 http://flybase.org/reports/FBgn0027603 - protein_coding_gene SUMO-specific protease activity ; GO:0016929 | inferred from sequence or structural similarity with SGD:S000005941 protein binding ; GO:0005515 | inferred from physical interaction with krz SUMO-specific protease activity ; GO:0016929 | inferred from direct assay endopeptidase activity ; GO:0004175 | inferred from biological aspect of ancestor with PANTHER:PTN000288424 central nervous system projection neuron axonogenesis ; GO:0021952 | inferred from mutant phenotype protein desumoylation ; GO:0016926 | inferred from sequence or structural similarity with SGD:S000005941 negative regulation of inflammatory response ; GO:0050728 | inferred from mutant phenotype negative regulation of Toll signaling pathway ; GO:0045751 | inferred from mutant phenotype cellular response to hypoxia ; GO:0071456 | inferred from mutant phenotype dendritic spine morphogenesis ; GO:0060997 | inferred from mutant phenotype negative regulation of lamellocyte differentiation ; GO:0035204 | inferred from mutant phenotype proteolysis ; GO:0006508 | inferred from direct assay protein desumoylation ; GO:0016926 | inferred from mutant phenotype protein desumoylation ; GO:0016926 | inferred from direct assay nuclear pore ; GO:0005643 | inferred from direct assay nuclear inner membrane ; GO:0005637 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "Ulp1, CG12359, DmUlp1, BcDNA:GH02751, ulp1" "IPR003653:Ulp1 protease family, C-terminal catalytic domain" CG12359 27-Aug-18 DroID_v2018_08 "Drer\eif4a1a, Drer\senp8, Drer\senp3a, Drer\senp5, Drer\senp2, Drer\si:dkey-21c19.3, Drer\senp3b" Scer\ULP1 "Cele\K04F10.7, Cele\ulp-2, Cele\ulp-3, Cele\ulp-1" - "Mmus\Senp8, Mmus\Senp2, Mmus\Senp1, Mmus\4930444G20Rik, Mmus\Gm5415, Mmus\AF366264, Mmus\Senp3, Mmus\Gm9839, Mmus\Senp5" "Hsap\SENP8, Hsap\SENP2, Hsap\SENP1, Hsap\SENP5, Hsap\SENP3" "viable,fertile,male sterile,lethal,recessive,partially lethal - majority die,visible" "denticle belt,mesothoracic tergum" FBgn0003063 anon-Pen68A anon-Pen68A http://flybase.org/reports/FBgn0003063 - gene - - - "GCR-16, pen68A, Pen68A, GCR16, anon-Pen68A" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039157 Myo95E Myosin 95E http://flybase.org/reports/FBgn0039157 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001609 motor activity ; GO:0003774 | inferred from electronic annotation with InterPro:IPR001609, InterPro:IPR010926" determination of left/right symmetry ; GO:0007368 | NOT inferred from mutant phenotype biological_process ; GO:0008150 | no biological data available "myosin complex ; GO:0016459 | inferred from electronic annotation with InterPro:IPR001609, InterPro:IPR010926" "CG5501, Dm95E, 95E, DmAE003746, CG31135, CG31134, Myo95E, myo 95E, Myo5" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR000048:IQ motif, EF-hand binding site, IPR001609:Myosin head, motor domain, IPR010926:Class I myosin tail homology domain" CG5501 27-Aug-18 DroID_v2018_08 "Drer\myo1ea, Drer\si:dkeyp-92c9.3, Drer\si:ch211-94l19.4, Drer\myo1ca, Drer\myo1f, Drer\myo1hb, Drer\myo1ha, Drer\myo1cb, Drer\myo1eb, Drer\myo5c, Drer\myo1b" "Scer\MYO3, Scer\MYO5" "Cele\hum-9, Cele\hum-1, Cele\hum-5" "Xtro\myo1h, Xtro\myo1e.1, Xtro\myo1c, Xtro\myo1f, Xtro\myo1d, Xtro\myo1a" "Mmus\Myo1h, Mmus\Myo1b, Mmus\Myo1e, Mmus\Myo1c, Mmus\Myo1g, Mmus\Myo1f, Mmus\Myo1a, Mmus\Myo1d" "Hsap\MYO1F, Hsap\MYO1D, Hsap\MYO1B, Hsap\MYO1E, Hsap\MYO1H, Hsap\MYO1A, Hsap\MYO1C, Hsap\MYO1G" viable male genitalia FBgn0033710 CG17739 - http://flybase.org/reports/FBgn0033710 protein_coding_gene serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR002223 - - "CT39321, anon-WO0153538.35, CG17739" "IPR000884:Thrombospondin type-1 (TSP1) repeat, IPR002223:Pancreatic trypsin inhibitor Kunitz domain, IPR002861:Reeler domain, IPR009465:Spondin, N-terminal" CG17739 27-Aug-18 DroID_v2018_08 "Drer\spon1a, Drer\spon1b, Drer\thsd7bb, Drer\thsd7ba, Drer\thsd7aa" - Cele\spon-1 "Xtro\thsd7a, Xtro\thsd7b, Xtro\spon1" "Mmus\Thsd7b, Mmus\Reln, Mmus\Spon1, Mmus\Thsd7a, Mmus\Spon2" "Hsap\SPON1, Hsap\RELN, Hsap\THSD7A, Hsap\THSD7B, Hsap\SPON2" viable FBgn0262858 CG43222 - http://flybase.org/reports/FBgn0262858 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43222, DMG4-MB6.chr3R.35.021" - CG43222 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0064162 lin-10 lin-10 http://flybase.org/reports/FBgn0064162 gene - - - "Flin-10, lin-10" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0054034 CG34034 - http://flybase.org/reports/FBgn0054034 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "BP1088, HDC14863, CG34034" - CG34034 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032478 CG5458 - http://flybase.org/reports/FBgn0032478 protein_coding_gene molecular_function ; GO:0003674 | no biological data available axoneme assembly ; GO:0035082 | inferred from sequence or structural similarity with HGNC:12371 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:12371 cytosol ; GO:0005829 | inferred from sequence or structural similarity with HGNC:12371 CG5458 IPR003409:MORN motif CG5458 27-Aug-18 DroID_v2018_08 "Drer\jph3, Drer\als2b, Drer\rsph10b, Drer\rsph1, Drer\jph2, Drer\als2a, Drer\morn4, Drer\jph1b, Drer\jph1a, Drer\si:ch211-146m13.3" - - "Xtro\als2cl, Xtro\morn5, Xtro\rsph10b, Xtro\als2, Xtro\rsph1, Xtro\jph2, Xtro\jph1" "Mmus\Morn5, Mmus\Jph2, Mmus\Jph4, Mmus\Jph3, Mmus\Morn4, Mmus\Jph1, Mmus\Morn3, Mmus\Rsph1, Mmus\Morn1, Mmus\Als2, Mmus\Als2cl" "Hsap\MORN1, Hsap\JPH2, Hsap\JPH4, Hsap\JPH1, Hsap\ALS2CL, Hsap\ALS2, Hsap\MORN5, Hsap\RSPH1, Hsap\RSPH10B, Hsap\MORN4, Hsap\RSPH10B2, Hsap\JPH3, Hsap\MORN3" viable FBgn0003560 Su(f)D "Suppressor of forked, Dominant" http://flybase.org/reports/FBgn0003560 - gene - - - "Su[D]-f, Su(f)D, Su(f)" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,female semi-sterile" macrochaeta FBgn0039480 Cpr97Ea Cuticular protein 97Ea http://flybase.org/reports/FBgn0039480 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr97Ea, CG6131" IPR000618:Insect cuticle protein CG6131 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0040031 CG12061 - http://flybase.org/reports/FBgn0040031 protein_coding_gene "calcium channel activity ; GO:0005262 | inferred from biological aspect of ancestor with PANTHER:PTN000090975 potassium ion binding ; GO:0030955 | inferred from biological aspect of ancestor with PANTHER:PTN000090975 calcium ion binding ; GO:0005509 | inferred from biological aspect of ancestor with PANTHER:PTN000090975 calcium, potassium:sodium antiporter activity ; GO:0008273 | inferred from biological aspect of ancestor with PANTHER:PTN000090975 sodium ion binding ; GO:0031402 | inferred from biological aspect of ancestor with PANTHER:PTN000090975" transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR004837 cellular calcium ion homeostasis ; GO:0006874 | inferred from biological aspect of ancestor with PANTHER:PTN000090975 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000090975 "CG40148, CG12061" "IPR004837:Sodium/calcium exchanger membrane region, IPR004481:Sodium/potassium/calcium exchanger" CG12061 27-Aug-18 DroID_v2018_08 "Drer\slc24a1, Drer\slc24a2, Drer\slc24a3, Drer\si:ch73-335m24.5, Drer\slc24a5, Drer\slc24a4a, Drer\slc24a4b" Scer\YDL206W "Cele\ncx-5, Cele\ncx-4" "Xtro\slc24a3, Xtro\slc24a4, Xtro\slc24a5, Xtro\slc24a2" "Mmus\Slc24a5, Mmus\Slc24a1, Mmus\Slc24a4, Mmus\Slc24a3, Mmus\Slc24a2" "Hsap\SLC24A5, Hsap\SLC24A2, Hsap\SLC24A3, Hsap\SLC24A1, Hsap\SLC24A4" viable FBgn0261627 CG42710 - http://flybase.org/reports/FBgn0261627 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42710, HDC01517" - CG42710 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060681 l(3)S076304 lethal (3) S076304 http://flybase.org/reports/FBgn0060681 gene - - - "0763/04, l(3)S076304" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0031951 r2d2 r2d2 http://flybase.org/reports/FBgn0031951 protein_coding_gene double-stranded RNA binding ; GO:0003725 | inferred from sequence or structural similarity regulation of production of small RNA involved in gene silencing by RNA ; GO:0070920 | inferred from direct assay heterochromatin organization involved in chromatin silencing ; GO:0070868 | inferred from mutant phenotype defense response to virus ; GO:0051607 | inferred from mutant phenotype siRNA loading onto RISC involved in RNA interference ; GO:0035087 | inferred from direct assay ovarian follicle cell stalk formation ; GO:0030713 | inferred from mutant phenotype production of siRNA involved in RNA interference ; GO:0030422 | inferred from direct assay siRNA loading onto RISC involved in RNA interference ; GO:0035087 | traceable author statement production of small RNA involved in gene silencing by RNA ; GO:0070918 | inferred from direct assay RISC complex ; GO:0016442 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "r2d2, R2D2, cg7138, CG7138, R2d2" IPR014720:Double-stranded RNA-binding domain CG7138 27-Aug-18 DroID_v2018_08 "Drer\ilf3a, Drer\adarb1a, Drer\prkra, Drer\ilf3b, Drer\strbp, Drer\adarb1b, Drer\stau2, Drer\tarbp2, Drer\stau1, Drer\adarb2" - "Cele\stau-1, Cele\R11H6.5" "Xtro\tarbp2, Xtro\stau1, Xtro\stau2" "Mmus\Stau1, Mmus\Stau2, Mmus\Adarb1, Mmus\Prkra, Mmus\Strbp, Mmus\Tarbp2, Mmus\Adarb2, Mmus\Ilf3" "Hsap\STAU1, Hsap\STAU2, Hsap\STRBP, Hsap\ILF3, Hsap\TARBP2, Hsap\ADARB1, Hsap\PRKRA, Hsap\ADARB2" "immune response defective,recessive,lethal,maternal effect,suppressor of variegation,dominant,conditional,visible,partially lethal - majority die,some die during pupal stage" "interfollicle cell,follicle cell,egg chamber,somatic clone,trichogen cell" FBgn0045045 fs(1)38 female sterile (1) 38 http://flybase.org/reports/FBgn0045045 gene molecular_function ; GO:0003674 | no biological data available eggshell chorion assembly ; GO:0007306 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(1)38 - - 27-Aug-18 DroID_v2018_08 - - - - - - female sterile "egg,chorion" FBgn0259538 GG01022 - http://flybase.org/reports/FBgn0259538 gene - - - GG01022 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "leg,unguis,tarsal segment,arista" FBgn0065955 l(2)SH0062 lethal (2) SH0062 http://flybase.org/reports/FBgn0065955 gene - - - "l(2)SH0062, l(2)SH2 0062" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0037517 CG10086 - http://flybase.org/reports/FBgn0037517 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG10086 "IPR011021:Arrestin-like, N-terminal, IPR011022:Arrestin C-terminal-like domain, IPR014756:Immunoglobulin E-set" CG10086 27-Aug-18 DroID_v2018_08 "Drer\zgc:110353, Drer\zgc:110626, Drer\arrdc3a, Drer\arrdc1a, Drer\txnipb, Drer\si:ch211-130m23.2, Drer\arrdc1b, Drer\arrdc3b, Drer\LOC799768, Drer\arrdc2, Drer\txnipa" "Scer\ROG3, Scer\LDB19, Scer\RIM8, Scer\ALY2, Scer\ALY1, Scer\ECM21, Scer\ROD1, Scer\ART5, Scer\CSR2" "Cele\arrd-13, Cele\arrd-3, Cele\arrd-9, Cele\arrd-4, Cele\arrd-14, Cele\arrd-1, Cele\arrd-6, Cele\arrd-5, Cele\arrd-15, Cele\arrd-18, Cele\arrd-2, Cele\arrd-11, Cele\arrd-25, Cele\arrd-23, Cele\arrd-8, Cele\rnh-1.2, Cele\arrd-16, Cele\arrd-19, Cele\arrd-27, Cele\arrd-24, Cele\arrd-7, Cele\arrd-22, Cele\arrd-12" "Xtro\arrdc4, Xtro\txnip, Xtro\arrdc3, Xtro\arrdc2" "Mmus\Txnip, Mmus\Arrdc1, Mmus\Arrdc4, Mmus\Arrdc5, Mmus\Arrdc2, Mmus\Arrdc3" "Hsap\ARRDC2, Hsap\ARRDC4, Hsap\ARRDC1, Hsap\TXNIP, Hsap\ARRDC5, Hsap\ARRDC3" viable FBgn0260077 2L0944 - http://flybase.org/reports/FBgn0260077 gene - - - 2L0944 - - 27-Aug-18 DroID_v2018_08 - - - - - - "decreased cell size,somatic clone,lethal,recessive" "embryonic/larval tracheal system,somatic clone" FBgn0058441 CR40441 - http://flybase.org/reports/FBgn0058441 pseudogene_attribute - - - "CR40441, CG40441" - CR40441 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0261538 CG42662 - http://flybase.org/reports/FBgn0261538 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42662 - CG42662 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001260 inaA inactivation no afterpotential A http://flybase.org/reports/FBgn0001260 - gene - - - inaA - - 27-Aug-18 DroID_v2018_08 - - - - - - "neurophysiology defective,visual behavior defective" "photoreceptor cell R1,photoreceptor cell R2,photoreceptor cell R3,photoreceptor cell R4,photoreceptor cell R5,photoreceptor cell R6" FBgn0265547 lncRNA:CR44397 - http://flybase.org/reports/FBgn0265547 non_protein_coding_gene - - - "CR44397, lincRNA.176" - CR44397 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0261873 sdt stardust http://flybase.org/reports/FBgn0261873 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with par-6 guanylate kinase activity ; GO:0004385 | inferred from sequence or structural similarity with MGI:MGI:1927339 establishment of epithelial cell polarity ; GO:0090162 | inferred from electronic annotation with InterPro:IPR031185 bicellular tight junction assembly ; GO:0070830 | inferred from electronic annotation with InterPro:IPR031185 establishment or maintenance of epithelial cell apical/basal polarity ; GO:0045197 | inferred from expression pattern inferred from mutant phenotype inferred from physical interaction with crb zonula adherens assembly ; GO:0045186 | traceable author statement apical protein localization ; GO:0045176 | inferred from mutant phenotype zonula adherens assembly ; GO:0045186 | inferred from mutant phenotype morphogenesis of an epithelium ; GO:0002009 | non-traceable author statement morphogenesis of a polarized epithelium ; GO:0001738 | traceable author statement cell-cell junction assembly ; GO:0007043 | non-traceable author statement establishment or maintenance of polarity of embryonic epithelium ; GO:0016332 | inferred from mutant phenotype photoreceptor cell development ; GO:0042461 | inferred from mutant phenotype chitin-based cuticle development ; GO:0040003 | inferred from mutant phenotype establishment or maintenance of neuroblast polarity ; GO:0045196 | NOT inferred from expression pattern inferred from mutant phenotype morphogenesis of an epithelium ; GO:0002009 | traceable author statement lateral inhibition ; GO:0046331 | inferred from mutant phenotype establishment or maintenance of neuroblast polarity ; GO:0045196 | NOT inferred from mutant phenotype establishment or maintenance of cell polarity ; GO:0007163 | non-traceable author statement apical plasma membrane ; GO:0016324 | non-traceable author statement apical plasma membrane ; GO:0016324 | inferred from direct assay adherens junction ; GO:0005912 | inferred from direct assay apical cortex ; GO:0045179 | inferred from direct assay subapical complex ; GO:0035003 | traceable author statement septate junction ; GO:0005918 | traceable author statement subapical complex ; GO:0035003 | inferred from physical interaction with Patj apical plasma membrane ; GO:0016324 | traceable author statement apicolateral plasma membrane ; GO:0016327 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "CG32717, Sdt, sdt, CG12657, PALS1, Std, CG15341, CG15339, std, anon-EST:fe2E6, l(1)7Ef, CG1617, CG15340, CG12658, CG15342, pal1, Pals1, BP1063, cMAGUK1, cGUK1" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR011990:Tetratricopeptide-like helical domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR014775:L27 domain, C-terminal, IPR011511:Variant SH3 domain, IPR008145:Guanylate kinase/L-type calcium channel beta subunit, IPR008144:Guanylate kinase-like domain, IPR004172:L27 domain, IPR001478:PDZ domain, IPR001452:SH3 domain, IPR020590:Guanylate kinase, conserved site, IPR031185:MAGUK p55 subfamily member 5" CG32717 27-Aug-18 DroID_v2018_08 "Drer\mpp1, Drer\mpp5b, Drer\mpp2a, Drer\mpp5a, Drer\mpp6b, Drer\mpp7a, Drer\mpp3a, Drer\mpp6a, Drer\caska, Drer\mpp4a, Drer\mpp2b, Drer\mpp7b, Drer\mpp3b, Drer\si:ch73-272h16.4, Drer\LOC556594" - "Cele\magu-2, Cele\magu-1, Cele\lin-2" "Xtro\mpp6, Xtro\mpp2, Xtro\mpp7, Xtro\mpp1, Xtro\mpp5, Xtro\cask" "Mmus\Mpp5, Mmus\Cask, Mmus\Mpp7, Mmus\Mpp1, Mmus\Mpp3, Mmus\Mpp4, Mmus\Mpp2, Mmus\Mpp6" "Hsap\MPP1, Hsap\MPP3, Hsap\MPP4, Hsap\MPP2, Hsap\CASK, Hsap\MPP6, Hsap\MPP7, Hsap\MPP5" pupal stage photoreceptor cell stalk | apical

FBgn0000420 dbl dichaete beadex lethal http://flybase.org/reports/FBgn0000420 - gene - - - dbl - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,visible,cold sensitive" wing FBgn0051529 CG31529 - http://flybase.org/reports/FBgn0051529 protein_coding_gene - - - "BcDNA:LD01463, CG31529" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030250 CG15206 - http://flybase.org/reports/FBgn0030250 protein_coding_gene - - - CG15206 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0028519 hll heimdall http://flybase.org/reports/FBgn0028519 protein_coding_gene long-chain fatty acid-CoA ligase activity ; GO:0004467 | inferred from direct assay long-chain fatty acid-CoA ligase activity ; GO:0004467 | inferred from sequence or structural similarity long-chain fatty acid-CoA ligase activity ; GO:0004467 | inferred from sequence or structural similarity with UniProtKB:Q9V3S9 mesoderm development ; GO:0007498 | inferred from expression pattern long-chain fatty acid metabolic process ; GO:0001676 | inferred from sequence or structural similarity with UniProtKB:Q9V3S9 fatty acid metabolic process ; GO:0006631 | inferred from mutant phenotype locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from expression pattern inferred from mutant phenotype neuron cellular homeostasis ; GO:0070050 | inferred from mutant phenotype triglyceride homeostasis ; GO:0070328 | inferred from mutant phenotype - "2a9, BG:DS05899.1, I, anon-EST:CL2a9, CG4500, hll, dbb" IPR000873:AMP-dependent synthetase/ligase CG4500 27-Aug-18 DroID_v2018_08 "Drer\acsl2, Drer\acsl1b, Drer\acsl4a, Drer\acsl1a, Drer\acsl5, Drer\acsl4b, Drer\acsbg2, Drer\acsl3b, Drer\acsbg1, Drer\acsl6" "Scer\FAA1, Scer\FAA4, Scer\FAA3, Scer\FAA2" Cele\acs-5 "Xtro\acsl6, Xtro\acsl4, Xtro\acsbg2, Xtro\acsl5, Xtro\acsbg1, Xtro\acsl1" "Mmus\Acsl3, Mmus\Acsl6, Mmus\1700061G19Rik, Mmus\Acsbg2, Mmus\Acsl1, Mmus\Acsl4, Mmus\Acsl5, Mmus\Acsbg1" "Hsap\ACSL4, Hsap\ACSBG2, Hsap\ACSL6, Hsap\ACSL3, Hsap\ACSBG1, Hsap\ACSL1, Hsap\ACSL5" " embryonic stage | stage 5 , embryonic stage | stage 17 , embryonic stage , embryonic stage | stage >5 " " mesoderm anlage

, embryonic/larval fat body

, ventral furrow

, yolk

, mesoderm

" viable FBgn0061037 l(3)S023844b lethal (3) S023844b http://flybase.org/reports/FBgn0061037 gene - - - "0238/44, l(3)S023844b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0035704 Vps8 Vacuolar protein sorting 8 http://flybase.org/reports/FBgn0035704 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model GTPase binding ; GO:0051020 | inferred from sequence or structural similarity with SGD:S000000002 intracellular protein transport ; GO:0006886 | inferred from electronic annotation with InterPro:IPR000547 vesicle-mediated transport ; GO:0016192 | inferred from electronic annotation with InterPro:IPR000547 endosomal transport ; GO:0016197 | inferred from sequence or structural similarity with SGD:S000000002 CORVET complex ; GO:0033263 | inferred from sequence or structural similarity with SGD:S000000002 "anon-WO0118547.365, CG10144, Vps8" "IPR025941:Vacuolar protein sorting-associated protein 8, central domain, IPR011047:Quinoprotein alcohol dehydrogenase-like superfamily, IPR001841:Zinc finger, RING-type, IPR015943:WD40/YVTN repeat-like-containing domain, IPR000547:Clathrin, heavy chain/VPS, 7-fold repeat, IPR011990:Tetratricopeptide-like helical domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG10144 27-Aug-18 DroID_v2018_08 Drer\vps8 Scer\VPS8 Cele\C42C1.4 Xtro\vps8 Mmus\Vps8 Hsap\VPS8 viable FBgn0262018 CadN2 Cadherin-N2 http://flybase.org/reports/FBgn0262018 protein_coding_gene "calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR000233, InterPro:IPR001881, InterPro:IPR002126, InterPro:IPR015919 calcium ion binding ; GO:0005509 | inferred from sequence model receptor activity ; GO:0004872 | inferred from sequence or structural similarity cell adhesion molecule binding ; GO:0050839 | inferred from sequence or structural similarity" "homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from electronic annotation with InterPro:IPR000233, InterPro:IPR002126 cell-cell adhesion mediated by cadherin ; GO:0044331 | inferred from sequence model R8 cell development ; GO:0045463 | inferred from mutant phenotype ommatidial rotation ; GO:0016318 | inferred from mutant phenotype homophilic cell adhesion via plasma membrane adhesion molecules ; GO:0007156 | inferred from sequence or structural similarity calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules ; GO:0016339 | inferred from sequence or structural similarity axon extension involved in axon guidance ; GO:0048846 | inferred from mutant phenotype R7 cell development ; GO:0045467 | inferred from mutant phenotype" plasma membrane ; GO:0005886 | inferred from electronic annotation with InterPro:IPR020894 integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity "CadN2, cadN2, N-Cad2, NCad2, DmNCad2, CG7527, CT23007, DN-like, DN-Cad2, DNcad2, DN-cad2, CG42829, Ncad2" "IPR000233:Cadherin, cytoplasmic domain, IPR000742:EGF-like domain, IPR001791:Laminin G domain, IPR001881:EGF-like calcium-binding domain, IPR002126:Cadherin, IPR013032:EGF-like, conserved site, IPR015919:Cadherin-like, IPR013320:Concanavalin A-like lectin/glucanase domain, IPR027397:Catenin binding domain, IPR020894:Cadherin conserved site" CG42829 27-Aug-18 DroID_v2018_08 "Drer\pcdh15b, Drer\cdh6, Drer\fat3a, Drer\si:ch211-186j3.6, Drer\pcdh1g30, Drer\pcdh2ab8, Drer\cdh5, Drer\pcdh15a, Drer\pcdh2g1, Drer\pcdh2g8, Drer\pcdh2ab6, Drer\dsc2l, Drer\cdh17, Drer\pcdh1g33, Drer\dchs1a, Drer\pcdh2ab2, Drer\cdh15, Drer\LOC567936, Drer\pcdh2ab11, Drer\fat1b, Drer\pcdh2ab7, Drer\cdh19, Drer\LOC100006797, Drer\fat1a, Drer\cdh26.1, Drer\pcdh1a6, Drer\pcdh2ab9, Drer\cdh8, Drer\cdh10a, Drer\pcdh1gb2, Drer\cdh23, Drer\si:dkey-22o22.2, Drer\pcdh2ab10, Drer\cdh13, Drer\pcdh1g22, Drer\cdh31, Drer\cdh2, Drer\LOC100536351, Drer\dchs1b, Drer\pcdh2ab5, Drer\cdh16, Drer\cdh12a, Drer\pcdh2ab3, Drer\si:dkey-30c15.10, Drer\cdh27, Drer\fat2, Drer\pcdh10a, Drer\cdh1, Drer\cdh4, Drer\pcdh2ab1, Drer\pcdh2aa15, Drer\cdh11, Drer\si:busm1-71b9.3, Drer\cdh7, Drer\pcdh2g3, Drer\LOC100329245, Drer\pcdh1gc5, Drer\pcdh10b, Drer\LOC103909937, Drer\pcdh1g18" - "Cele\cdh-12, Cele\hmr-1, Cele\akir-1, Cele\cdh-7" "Xtro\dchs2, Xtro\fat4, Xtro\fat1" "Mmus\Pcdhb9, Mmus\Pcdh10, Mmus\Cdh12, Mmus\Cdh17, Mmus\Cdh3, Mmus\Cdh24, Mmus\Fat1, Mmus\Pcdhac2, Mmus\Cdh10, Mmus\Dsc3, Mmus\Pcdhb17, Mmus\Cdh8, Mmus\Cdh2, Mmus\Pcdhb7, Mmus\Pcdhb4, Mmus\Cdh16, Mmus\Cdh6, Mmus\Cdh18, Mmus\Dsg2, Mmus\Dchs1, Mmus\Cdh7, Mmus\Pcdhb2, Mmus\Cdhr3, Mmus\Cdh26, Mmus\Pcdhb13, Mmus\Pcdh18, Mmus\Pcdh1, Mmus\Cdh1, Mmus\Fat3, Mmus\Pcdhb8, Mmus\Cdh4, Mmus\Pcdhb15, Mmus\Dsc1, Mmus\Cdh9, Mmus\Cdh13, Mmus\Pcdhb14, Mmus\Cdh22, Mmus\Pcdhb5, Mmus\Cdh15, Mmus\Cdh5, Mmus\Pcdhb16, Mmus\Pcdhb12, Mmus\Cdh20, Mmus\Dsg3, Mmus\Cdh23, Mmus\Dsc2, Mmus\Cdh11, Mmus\Fat2, Mmus\Pcdh17, Mmus\Cdh19, Mmus\Pcdhgc5" "Hsap\CDH10, Hsap\PCDHGB5, Hsap\PCDHGA10, Hsap\PCDHB2, Hsap\PCDHB4, Hsap\CDH12, Hsap\CDH15, Hsap\CDH7, Hsap\PCDHGA4, Hsap\CDH11, Hsap\PCDHA11, Hsap\CDHR3, Hsap\CDH22, Hsap\PCDHA1, Hsap\PCDH10, Hsap\CDH26, Hsap\PCDH18, Hsap\CDH9, Hsap\DSC3, Hsap\AKIRIN2, Hsap\CDH18, Hsap\PCDHB7, Hsap\CDH6, Hsap\CDH8, Hsap\PCDH1, Hsap\PCDHB6, Hsap\PCDHB8, Hsap\PCDH9, Hsap\PCDH17, Hsap\DLK2, Hsap\PCDHGC4, Hsap\AKIRIN1, Hsap\PCDHB13, Hsap\CDH23, Hsap\DSG2, Hsap\CDH4, Hsap\CDH17, Hsap\DSG4, Hsap\CDH5, Hsap\FAT2, Hsap\PCDHGB7, Hsap\CDH19, Hsap\DSG3, Hsap\FAT1, Hsap\PCDHGB1, Hsap\PCDHA3, Hsap\CDH20, Hsap\DSC2, Hsap\PCDHGA2, Hsap\PCDHA2, Hsap\CDH3, Hsap\DSC1, Hsap\CDH1, Hsap\CDH2, Hsap\DCHS1, Hsap\PCDHGC5, Hsap\PCDHGB4, Hsap\DCHS2, Hsap\FAT3, Hsap\PCDHGA12, Hsap\PCDHGA3, Hsap\PCDHA5, Hsap\CDH24, Hsap\FAT4, Hsap\CDH13" "viable,partially lethal - majority die,some die during pupal stage" FBgn0065135 l(3)SH118 lethal (3) SH118 http://flybase.org/reports/FBgn0065135 gene - - - "l(3)SH118, l(2)SH3 118" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0065623 l(2)SH0799 lethal (2) SH0799 http://flybase.org/reports/FBgn0065623 gene - - - "l(2)SH0799, l(2)SH2 0799" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0038961 CG13850 - http://flybase.org/reports/FBgn0038961 protein_coding_gene protein kinase activity ; GO:0004672 | inferred from electronic annotation with InterPro:IPR010622 protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with HGNC:24676 - "GH07286p, CG13850" "IPR010622:FAST kinase leucine-rich, IPR013579:FAST kinase-like protein, subdomain 2, IPR013584:RAP domain" CG13850 27-Aug-18 DroID_v2018_08 "Drer\fastk, Drer\fastkd1, Drer\tbrg4, Drer\fastkd3, Drer\fastkd5, Drer\fastkd2" - "Cele\fbxa-46, Cele\C52E2.5, Cele\B0564.7" "Xtro\fastkd3, Xtro\fastkd5, Xtro\fastkd1, Xtro\tbrg4" "Mmus\Fastkd5, Mmus\Tbrg4, Mmus\Fastk, Mmus\Fastkd2, Mmus\Fastkd1, Mmus\Fastkd3" "Hsap\FASTKD5, Hsap\FASTK, Hsap\FASTKD1, Hsap\TBRG4, Hsap\FASTKD3, Hsap\FASTKD2" viable FBgn0022086 l(2)k07408 lethal (2) k07408 http://flybase.org/reports/FBgn0022086 - gene - - - "l(2)K07408, l(2)k07408" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0004049 yrt yurt http://flybase.org/reports/FBgn0004049 "FBgn0000466, FBgn0002363, FBgn0038155" protein_coding_gene cytoskeletal protein binding ; GO:0008092 | inferred from electronic annotation with InterPro:IPR000798 structural constituent of cytoskeleton ; GO:0005200 | inferred from biological aspect of ancestor with PANTHER:PTN001150527 cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity eye photoreceptor cell development ; GO:0042462 | inferred from mutant phenotype establishment or maintenance of apical/basal cell polarity ; GO:0035088 | inferred from mutant phenotype amnioserosa maintenance ; GO:0046665 | inferred from mutant phenotype germ-band shortening ; GO:0007390 | inferred from mutant phenotype establishment of epithelial cell apical/basal polarity ; GO:0045198 | inferred from genetic interaction with aPKC actomyosin structure organization ; GO:0031032 | inferred from biological aspect of ancestor with PANTHER:PTN001150527 head involution ; GO:0008258 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype extrinsic component of membrane ; GO:0019898 | inferred from electronic annotation with InterPro:IPR000798 cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR000798 zonula adherens ; GO:0005915 | inferred from direct assay cytoskeleton ; GO:0005856 | inferred from biological aspect of ancestor with PANTHER:PTN001150527 septate junction ; GO:0005918 | inferred from direct assay basolateral plasma membrane ; GO:0016323 | inferred from direct assay "yrt, l(3)m112, CG9764, Nbl4, l(3)87Ek, m112, l(3)E19, dlhB, Yrt" "IPR000299:FERM domain, IPR000798:Ezrin/radixin/moesin-like, IPR011993:PH domain-like, IPR014352:FERM/acyl-CoA-binding protein, 3-helical bundle, IPR014847:FERM adjacent (FA), IPR018980:FERM, C-terminal PH-like domain, IPR018979:FERM, N-terminal, IPR019747:FERM conserved site, IPR019748:FERM central domain, IPR019749:Band 4.1 domain, IPR029071:Ubiquitin-related domain" CG9764 27-Aug-18 DroID_v2018_08 "Drer\epb41l4b, Drer\epb41l5" - Cele\frm-2 Xtro\epb41l5 "Mmus\Epb41l5, Mmus\Epb41l4b" "Hsap\EPB41L4B, Hsap\EPB41L5" "lethal,cell polarity defective,germline clone,lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,viable" "macrochaeta,ommatidium,epidermis,germline clone,trachea,embryonic/first instar larval cuticle,eye photoreceptor cell stalk,eye photoreceptor cell,conditional,rhabdomere of eye photoreceptor cell,adherens junction,embryonic head,amnioserosa,embryo,dorsal,posterior,dorsal ridge,embryonic/larval cuticle" FBgn0259369 EP-596 - http://flybase.org/reports/FBgn0259369 gene - - - EP-596 - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,lethal" "wing,wing margin" FBgn0036852 CG14083 - http://flybase.org/reports/FBgn0036852 protein_coding_gene - - - CG14083 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260327 GSd031 - http://flybase.org/reports/FBgn0260327 gene - - - GSd031 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,neuroanatomy defective" ventral nerve cord FBgn0085606 CG41310 - http://flybase.org/reports/FBgn0085606 protein_coding_gene - - - CG41310 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0019797 l(1)08 lethal (1) 08 http://flybase.org/reports/FBgn0019797 - gene - - - l(1)08 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,heat sensitive" FBgn0000700 fltF flight defective F http://flybase.org/reports/FBgn0000700 - gene - - - fltF - - 27-Aug-18 DroID_v2018_08 - - - - - - "jumping defective,flight defective" FBgn0038858 CG5793 - http://flybase.org/reports/FBgn0038858 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR011234 metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR011234 - "CG5793, FBgn0038858" "IPR011234:Fumarylacetoacetase, C-terminal-related" CG5793 27-Aug-18 DroID_v2018_08 "Drer\fahd1, Drer\fahd2a" Scer\FMP41 Cele\fahd-1 "Xtro\fahd2a, Xtro\fahd1" "Mmus\Fahd1, Mmus\Fahd2a" "Hsap\FAHD1, Hsap\FAHD2B, Hsap\FAHD2A" viable FBgn0262875 CG43230 - http://flybase.org/reports/FBgn0262875 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43230 - CG43230 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0028173 l(3)S026430 lethal (3) S026430 http://flybase.org/reports/FBgn0028173 gene - - - "0264/30, l(3)S026430" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0265146 CG44215 - http://flybase.org/reports/FBgn0265146 protein_coding_gene - - - "CR44215, CG44215" - CG44215 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0014242 l(2)32Ac lethal (2) 32Ac http://flybase.org/reports/FBgn0014242 - gene - - - l(2)32Ac - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0002221 l(3)68Aa lethal (3) 68Aa http://flybase.org/reports/FBgn0002221 - gene - - - "l(3)C288, l(3)68Aa" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,partially lethal - majority die,visible,lethal - all die before end of larval stage,some die during larval stage" macrochaeta FBgn0267193 lncRNA:CR45633 - http://flybase.org/reports/FBgn0267193 non_protein_coding_gene - - - CR45633 - CR45633 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037852 Tpc1 Thiamine pyrophosphate carrier protein 1 http://flybase.org/reports/FBgn0037852 protein_coding_gene thiamine pyrophosphate-transporting ATPase activity ; GO:0015619 | inferred from direct assay transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR002067 mitochondrial transport ; GO:0006839 | inferred from genetic interaction with SGD:S000003328 thiamine pyrophosphate transport ; GO:0030974 | inferred from direct assay integral component of mitochondrial inner membrane ; GO:0031305 | inferred from biological aspect of ancestor with PANTHER:PTN000756668 "CG6608, Tpc1, DmTpc1, Q9VGU9" "IPR002067:Mitochondrial carrier protein, IPR018108:Mitochondrial substrate/solute carrier, IPR023395:Mitochondrial carrier domain" CG6608 27-Aug-18 DroID_v2018_08 "Drer\slc25a43, Drer\slc25a19, Drer\slc25a16" "Scer\YPR011C, Scer\LEU5, Scer\TPC1" "Cele\C47E12.2, Cele\F47B8.10, Cele\hpo-12" "Xtro\slc25a43, Xtro\slc25a19, Xtro\slc25a42" "Mmus\Slc25a43, Mmus\Slc25a42, Mmus\Slc25a19, Mmus\Slc25a16" "Hsap\SLC25A43, Hsap\SLC25A16, Hsap\SLC25A42, Hsap\SLC25A19" "visible,viable" wing DRSC15614 I -0.252611386 -2.59170152 -0.350131061 -1.220479227 0.552369677 0.253307087 FBgn0250841 CG17242 - http://flybase.org/reports/FBgn0250841 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern" extracellular space ; GO:0005615 | inferred from direct assay "CG17242, SPH187, anon-SAGE:Wang-110" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan" CG17242 27-Aug-18 DroID_v2018_08 Drer\si:ch211-165b19.9 - Cele\try-1 - "Mmus\Egfbp2, Mmus\Tmprss11a, Mmus\Tmprss11g, Mmus\Klk1b3, Mmus\Tmprss11f, Mmus\Prss53, Mmus\Klk1b8, Mmus\Klk1b9, Mmus\Prss50, Mmus\Klk1b5" "Hsap\CFD, Hsap\PRSS50, Hsap\TMPRSS11F, Hsap\TMPRSS11A, Hsap\PRSS36" FBgn0002057 l(2)40Fa lethal (2) 40Fa http://flybase.org/reports/FBgn0002057 - gene - - - "40Fa, l(2Lh)Fa, 40-18, GroupIX, l(2)EMS56-8, l(2)40Fa" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage,dominant,lethal" eye FBgn0002233 l(3)68Bf lethal (3) 68Bf http://flybase.org/reports/FBgn0002233 - gene - - - "l(3)B76, l(3)K, l(3)68Bf" - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive,lethal,polyphasic" "leg,wing" FBgn0264294 Cyt-b5 Cytochrome b5 http://flybase.org/reports/FBgn0264294 protein_coding_gene heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR018506 regulation of hemocyte proliferation ; GO:0035206 | inferred from mutant phenotype regulation of hemocyte differentiation ; GO:0045610 | inferred from mutant phenotype endomembrane system ; GO:0012505 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay "Cyt-b5, CG2140, CYTB5, l(2)01857, 1857, BcDNA:RE66521, BcDNA:GH02503, CYT-B5, dpld, l(2)k00107" "IPR001199:Cytochrome b5-like heme/steroid binding domain, IPR018506:Cytochrome b5, heme-binding site" CG2140 27-Aug-18 DroID_v2018_08 "Drer\cyb5b, Drer\cyb5a" "Scer\CYB5, Scer\OLE1, Scer\CYB2, Scer\SCS7" "Cele\cytb-5.2, Cele\C25A1.5, Cele\cytb-5.1, Cele\D2023.1" "Xtro\cyb5b, Xtro\cyb5a" "Mmus\Cyb5d1, Mmus\Cyb5a, Mmus\Cyb5b, Mmus\Fa2h" "Hsap\FA2H, Hsap\CYB5B, Hsap\CYB5A" FBgn0082998 snoRNA:Psi28S-1192d snoRNA:Psi28S-1192d http://flybase.org/reports/FBgn0082998 snoRNA_gene - - - "snoRNA:Psi28S-1192d, Psi28S-1192d, psi28S-1192d, CR34594, chrX:16977850..16978043" - CR34594 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040477 cid centromere identifier http://flybase.org/reports/FBgn0040477 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR000164, InterPro:IPR007125 protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 microtubule motor activity ; GO:0003777 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with cal1" mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype positive regulation of chromatin silencing ; GO:0031937 | inferred from genetic interaction with BubR1 kinetochore assembly ; GO:0051382 | inferred from mutant phenotype kinetochore organization ; GO:0051383 | inferred from direct assay mitotic metaphase plate congression ; GO:0007080 | inferred from mutant phenotype chromosome segregation ; GO:0007059 | inferred from mutant phenotype spindle assembly ; GO:0051225 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype "chromosome, centromeric region ; GO:0000775 | inferred from direct assay condensed nuclear chromosome inner kinetochore ; GO:0000941 | inferred from direct assay kinetochore ; GO:0000776 | inferred from direct assay condensed nuclear chromosome, centromeric region ; GO:0000780 | inferred from direct assay nuclear nucleosome ; GO:0000788 | inferred from physical interaction with His2A, His2B, His4 CENP-A containing nucleosome ; GO:0043505 | inferred from direct assay kinetochore ; GO:0000776 |" "CID, Cid, cid, CENP-A, CID/CENP-A, cenH3, cenpA, CENP-A/CID, CENP-A/Cid, CG13329, BcDNA:RE21270, CenpA/CID, CenH3, CenH3[Cid], Cenp-A, Cid[Mel], CenpA, CENPA, CENH3, CenH3[CID]" "IPR000164:Histone H3/CENP-A, IPR007125:Histone H2A/H2B/H3, IPR009072:Histone-fold" CG13329 27-Aug-18 DroID_v2018_08 "Drer\hist2h3c, Drer\zgc:113984, Drer\h3f3b.1, Drer\LOC108190746, Drer\zgc:113983, Drer\h3f3a, Drer\LOC108190747, Drer\zgc:173552, Drer\h3f3c, Drer\h3f3d, Drer\cenpa" "Scer\HHT1, Scer\CSE4, Scer\HHT2" "Cele\ZC155.2, Cele\his-71, Cele\his-73, Cele\hcp-3, Cele\his-69, Cele\cpar-1, Cele\F20D6.9" "Xtro\h3f3b, Xtro\cenpa, Xtro\hist2h3d" "Mmus\H3f3b, Mmus\Hist1h3i, Mmus\H3f3a, Mmus\Hist1h3d, Mmus\Hist1h3f, Mmus\Hist1h3c, Mmus\Hist2h3c1, Mmus\Hist2h3b, Mmus\Hist1h3g, Mmus\Cenpa, Mmus\Hist1h3b, Mmus\Hist1h3h, Mmus\Hist1h3e, Mmus\Hist1h3a, Mmus\Hist2h3c2" "Hsap\HIST1H3B, Hsap\HIST2H3C, Hsap\HIST1H3E, Hsap\CENPA, Hsap\HIST1H3I, Hsap\HIST3H3, Hsap\HIST1H3F, Hsap\H3F3B, Hsap\HIST1H3G, Hsap\HIST1H3J, Hsap\H3F3C, Hsap\HIST2H3D, Hsap\HIST1H3A, Hsap\HIST1H3C, Hsap\H3F3A, Hsap\HIST2H3A, Hsap\HIST1H3H, Hsap\HIST1H3D" " egg stage | fertilized egg , adult stage , embryonic stage " " male pronucleus

, spermatid

, female pronucleus

" "mitotic cell cycle defective,visible,lethal,neuroanatomy defective,partially lethal - majority die,some die during pupal stage,lethal - all die before end of embryonic stage,some die during embryonic stage,cell cycle defective" "condensed nuclear chromosome,metaphase,nucleus,spindle,mitotic cell cycle,mitotic anaphase,anaphase & condensed nuclear chromosome,eye,ommatidium,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum,chromosome,anaphase,telophase,metaphase plate" FBgn0060839 l(3)S049514 lethal (3) S049514 http://flybase.org/reports/FBgn0060839 gene - - - "0495/14, l(3)S049514" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0015850 anon-10Cc anon-10Cc http://flybase.org/reports/FBgn0015850 - gene - - - anon-10Cc - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263943 BG00297 - http://flybase.org/reports/FBgn0263943 gene - - - BG00297 - - 27-Aug-18 DroID_v2018_08 - - - - - - "long lived,male limited,starvation stress response defective,temperature response defective,gravitaxis defective" FBgn0065234 l(2)SH2167 lethal (2) SH2167 http://flybase.org/reports/FBgn0065234 gene - - - "l(2)SH2167, l(2)SH2 2167" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0027343 fz3 frizzled 3 http://flybase.org/reports/FBgn0027343 FBgn0025619 protein_coding_gene transmembrane signaling receptor activity ; GO:0004888 | inferred from electronic annotation with InterPro:IPR017981 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 Wnt-protein binding ; GO:0017147 | inferred from physical interaction with Wnt2 inferred from physical interaction with wg Wnt-activated receptor activity ; GO:0042813 | inferred by curator from GO:0017147 transmembrane signaling receptor activity ; GO:0004888 | inferred from sequence or structural similarity "cell surface receptor signaling pathway ; GO:0007166 | inferred from electronic annotation with InterPro:IPR000539, InterPro:IPR017981 establishment or maintenance of cell polarity ; GO:0007163 | inferred from mutant phenotype G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with fz signal transduction ; GO:0007165 | inferred from sequence or structural similarity" "membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR000539, InterPro:IPR017981 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | non-traceable author statement" "fz3, CG16785, Dfz3, dfz3, DFz3, EG:34F3.6, dFz3, Dm Fz3, Fz3" "IPR017981:GPCR, family 2-like, IPR000539:Frizzled protein, IPR015526:Frizzled/secreted frizzled-related protein, IPR020067:Frizzled domain, IPR000504:RNA recognition motif domain" CG16785 27-Aug-18 DroID_v2018_08 "Drer\fzd5, Drer\fzd8a, Drer\si:cabz01033205.3, Drer\fzd2, Drer\sfrp1b, Drer\sfrp2l, Drer\fzd10, Drer\sfrp5, Drer\sfrp2, Drer\tlc, Drer\corin, Drer\smo, Drer\fzd9a, Drer\fzd8b, Drer\LOC101884738, Drer\fzd3a, Drer\fzd7a, Drer\fzd7b, Drer\frzb, Drer\fzd3b, Drer\fzd9b, Drer\szl, Drer\sfrp1a" - Cele\sfrp-1 "Xtro\fzd7, Xtro\smo, Xtro\fzd9, Xtro\fzd6, Xtro\fzd5, Xtro\fzd3, Xtro\frzb, Xtro\sfrp1, Xtro\fzd10, Xtro\sfrp2, Xtro\sfrpx, Xtro\fzd8, Xtro\cpz, Xtro\mfrp, Xtro\frzb2, Xtro\sfrp5, Xtro\col18a1, Xtro\corin, Xtro\szl, Xtro\fzd4, Xtro\fzd2" "Mmus\Fzd2, Mmus\Sfrp2, Mmus\Sfrp4, Mmus\Mfrp, Mmus\Corin, Mmus\Cpz, Mmus\Fzd3, Mmus\Fzd8, Mmus\Fzd4, Mmus\Fzd6, Mmus\Smo, Mmus\Frzb, Mmus\Sfrp1, Mmus\Fzd9, Mmus\Sfrp5, Mmus\Fzd10, Mmus\Fzd7, Mmus\Fzd1, Mmus\Fzd5" "Hsap\SFRP1, Hsap\CORIN, Hsap\SFRP2, Hsap\FZD4, Hsap\FZD8, Hsap\FZD1, Hsap\SMO, Hsap\MFRP, Hsap\FZD10, Hsap\FZD9, Hsap\CPZ, Hsap\FZD5, Hsap\SFRP4, Hsap\FZD6, Hsap\SFRP5, Hsap\FZD7, Hsap\FRZB, Hsap\FZD2, Hsap\FZD3" larval stage | third instar " dorsal mesothoracic disc | restricted

, ventral thoracic disc | resticted

, eye-antennal disc | resticted

" "viable,fertile" FBgn0005525 l(2)52ACb lethal (2) 52ACb http://flybase.org/reports/FBgn0005525 - gene - - - l(2)52ACb - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036076 CG10427 - http://flybase.org/reports/FBgn0036076 protein_coding_gene - - - CG10427 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0025166 l(2)38EFe lethal (2) 38EFe http://flybase.org/reports/FBgn0025166 - gene - - - l(2)38EFe - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile,lethal,recessive" FBgn0062575 Mod(var)E1178 Mod(var)E1178 http://flybase.org/reports/FBgn0062575 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "E1178, Mod(var)E1178" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,enhancer of variegation,non-enhancer of variegation,non-suppressor of variegation" FBgn0058442 CG40442 - http://flybase.org/reports/FBgn0058442 protein_coding_gene - - - CG40442 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0041167 anon-A6 anon-A6 http://flybase.org/reports/FBgn0041167 gene - - - "A6, anon-A6" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051236 CG31236 - http://flybase.org/reports/FBgn0051236 protein_coding_gene - - - "BcDNA:GM01352, CG31236" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264901 lncRNA:CR44092 - http://flybase.org/reports/FBgn0264901 non_protein_coding_gene - - - CR44092 - CR44092 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0083097 bi::org-1 bi::org-1 http://flybase.org/reports/FBgn0083097 engineered_fusion_gene - - - bi::org-1 - - 27-Aug-18 DroID_v2018_08 - - - - - - "eye,arista,leg,ectopic,ommatidium,microchaeta,interommatidial bristle" FBgn0040102 lectin-24Db lectin-24Db http://flybase.org/reports/FBgn0040102 protein_coding_gene carbohydrate binding ; GO:0030246 | inferred from sequence or structural similarity with Lectin-galC1 mannose binding ; GO:0005537 | inferred from direct assay galactose binding ; GO:0005534 | inferred from sequence or structural similarity fucose binding ; GO:0042806 | inferred from direct assay - - "CG2958, AC004371a, AC 004371A, lectin-24Db" "IPR001304:C-type lectin-like, IPR016186:C-type lectin-like/link domain, IPR016187:C-type lectin fold" CG2958 27-Aug-18 DroID_v2018_08 "Drer\hbl4, Drer\hbl2, Drer\illr1, Drer\hbl3, Drer\zmp:0000000937, Drer\illr3, Drer\LOC101882781, Drer\clec3ba, Drer\colec11, Drer\si:ch73-343l4.8, Drer\clec11a, Drer\si:ch211-125e6.14, Drer\hbl1, Drer\clec3bb" - "Cele\clec-149, Cele\clec-239, Cele\clec-78, Cele\clec-28" "Xtro\colec11, Xtro\clec10a, Xtro\colec10, Xtro\clec3b, Xtro\clec3a" "Mmus\Sftpa1, Mmus\Sftpd, Mmus\Olr1, Mmus\Selp, Mmus\Clec4g, Mmus\Clec4e, Mmus\Clec3b, Mmus\Clec10a, Mmus\Fcer2a, Mmus\Clec12b, Mmus\Klra17, Mmus\Mgl2, Mmus\Clec4a2, Mmus\Cd209b, Mmus\Clec11a, Mmus\Mbl2, Mmus\Clec1b, Mmus\Clec4a1, Mmus\Asgr2, Mmus\Klra9, Mmus\Klra4, Mmus\Clec4f, Mmus\Klra2, Mmus\Colec11, Mmus\Colec10, Mmus\Asgr1, Mmus\Cd207, Mmus\Mbl1, Mmus\Klra10" "Hsap\ASGR1, Hsap\CLEC4E, Hsap\ASGR2, Hsap\CLEC2B, Hsap\PRG3, Hsap\SFTPA2, Hsap\CD72, Hsap\COLEC10, Hsap\FCER2, Hsap\OLR1, Hsap\CLEC1B, Hsap\SFTPD, Hsap\KLRC2, Hsap\CLEC4M, Hsap\SFTPA1, Hsap\CLEC3A, Hsap\MBL2, Hsap\CLEC10A, Hsap\COLEC11, Hsap\CLEC1A, Hsap\CLEC3B, Hsap\CLEC4A, Hsap\CLEC4G, Hsap\CLEC4F, Hsap\CLEC11A" viable FBgn0003873 Tu Turned-up wing http://flybase.org/reports/FBgn0003873 - gene - - - Tu - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,viable" wing FBgn0065892 l(2)SH0217 lethal (2) SH0217 http://flybase.org/reports/FBgn0065892 gene - - - "l(2)SH0217, l(2)SH2 0217" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0061494 l(3)18304 lethal (3) 18304 http://flybase.org/reports/FBgn0061494 gene - - - l(3)18304 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" "embryonic head,germline clone,maternal effect,embryonic thorax,embryonic abdomen,ectopic" FBgn0000761 fs(1)A476 female sterile (1) A476 http://flybase.org/reports/FBgn0000761 - gene - - - fs(1)A476 - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive,lethal - all die before end of embryonic stage,rescuable maternal effect,some die during embryonic stage" FBgn0262544 CG43098 - http://flybase.org/reports/FBgn0262544 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43098, chr3L_3658997_3659727.0" - CG43098 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0014077 anon-10Ba anon-10Ba http://flybase.org/reports/FBgn0014077 - gene - - - "anon-10B, anon-10Ba" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060759 l(3)S063602 lethal (3) S063602 http://flybase.org/reports/FBgn0060759 gene - - - "0636/02, l(3)S063602" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0260817 gkt glaikit http://flybase.org/reports/FBgn0260817 protein_coding_gene double-stranded DNA binding ; GO:0003690 | inferred from biological aspect of ancestor with PANTHER:PTN000275870 3'-tyrosyl-DNA phosphodiesterase activity ; GO:0017005 | inferred from biological aspect of ancestor with PANTHER:PTN000275870 3'-tyrosyl-DNA phosphodiesterase activity ; GO:0017005 | inferred from sequence or structural similarity with UniProtKB:P38319 single-stranded DNA binding ; GO:0003697 | inferred from biological aspect of ancestor with PANTHER:PTN000275870 double-strand break repair ; GO:0006302 | inferred from biological aspect of ancestor with PANTHER:PTN000275870 single strand break repair ; GO:0000012 | inferred from biological aspect of ancestor with PANTHER:PTN000275870 DNA repair ; GO:0006281 | inferred from sequence or structural similarity with UniProtKB:P38319 central nervous system development ; GO:0007417 | inferred from mutant phenotype establishment or maintenance of epithelial cell apical/basal polarity ; GO:0045197 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:P38319 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000275870 "gkt, c22, Tdp1, CG8826, CG8825, anon-23Db, Gkt, TDP1" "IPR010347:Tyrosyl-DNA phosphodiesterase I, IPR019406:Zinc finger, C2H2, APLF-like, IPR027415:Tyrosyl-DNA phosphodiesterase C-terminal domain" CG8825 27-Aug-18 DroID_v2018_08 Drer\tdp1 Scer\TDP1 Cele\F52C12.1 Xtro\tdp1 Mmus\Tdp1 Hsap\TDP1 FBgn0017602 Hrb3 Hrb3 http://flybase.org/reports/FBgn0017602 - gene - - - Hrb3 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265678 lncRNA:CR44485 - http://flybase.org/reports/FBgn0265678 non_protein_coding_gene - - - CR44485 - CR44485 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051939 tRNA:Gln-CTG-2-4 transfer RNA:Glutamine-CTG 2-4 http://flybase.org/reports/FBgn0051939 tRNA_gene CAG codon-amino acid adaptor activity ; GO:0033428 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033428 cytosol ; GO:0005829 | inferred by curator from GO:0033428 "AE002638.trna6-GlnCTG, tRNA:Q:CTG:AE002638-c, CR31939, chr2L.trna39-GlnCTG, tRNA:Gln-CTG-2-4, tRNA:CR31939, tRNA-Gln-CTG-2-4, CAG" - CR31939 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0261877 Z2-2626 - http://flybase.org/reports/FBgn0261877 gene - sleep ; GO:0030431 | inferred from mutant phenotype - Z2-2626 - - 27-Aug-18 DroID_v2018_08 - - - - - - behavior defective FBgn0021792 l(2)k17031 lethal (2) k17031 http://flybase.org/reports/FBgn0021792 - gene - - - "l(2)k17035, l(2)k17031" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0014453 17.6\pol 17.6 element transposase http://flybase.org/reports/FBgn0014453 - transposable_element_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR012337 DNA integration ; GO:0015074 | inferred from electronic annotation with InterPro:IPR001584 - "17.6\T, 17.6\pol, pol" "IPR021109:Aspartic peptidase domain, IPR000477:Reverse transcriptase domain, IPR001584:Integrase, catalytic core, IPR012337:Ribonuclease H-like domain" - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0261708 CR42745 - http://flybase.org/reports/FBgn0261708 non_protein_coding_gene - - - CR42745 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037360 CG2182 - http://flybase.org/reports/FBgn0037360 protein_coding_gene - - cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001006389 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001006389 CG2182 IPR026073:Gametogenetin-binding protein 2 CG2182 27-Aug-18 DroID_v2018_08 Drer\ggnbp2 - - Xtro\ggnbp2 Mmus\Ggnbp2 Hsap\GGNBP2 viable FBgn0020828 l(2)SA104 lethal (2) SA104 http://flybase.org/reports/FBgn0020828 - gene - - - "l(2)SA#104, l(2)SA104" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0026227 l(1)16Fn lethal (1) 16Fn http://flybase.org/reports/FBgn0026227 - gene - - - "HL-IX, l(1)16Fn" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263611 lncRNA:CR43620 - http://flybase.org/reports/FBgn0263611 non_protein_coding_gene - - - CR43620 - CR43620 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032981 CG3635 - http://flybase.org/reports/FBgn0032981 protein_coding_gene "hydrolase activity, acting on ester bonds ; GO:0016788 | inferred from electronic annotation with InterPro:IPR025483" lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR006693 - CG3635 "IPR025483:Lipase, eukaryotic, IPR006693:Partial AB-hydrolase lipase domain, IPR029058:Alpha/Beta hydrolase fold" CG3635 27-Aug-18 DroID_v2018_08 Drer\lipf "Scer\YEH2, Scer\YEH1, Scer\TGL1" "Cele\lipl-8, Cele\lipl-6, Cele\lipl-4, Cele\lipl-7, Cele\lipl-3, Cele\lipl-2, Cele\lipl-1, Cele\lipl-5" Xtro\lipa "Mmus\Lipo3, Mmus\Lipn, Mmus\Lipa, Mmus\Lipm, Mmus\Lipo2, Mmus\Lipo4, Mmus\Lipo1, Mmus\Lipf, Mmus\Lipk" "Hsap\LIPK, Hsap\LIPJ, Hsap\LIPA, Hsap\LIPM, Hsap\LIPN, Hsap\LIPF" "viable,visible,body color defective" "trichogen cell,mesothoracic tergum" FBgn0263545 mir-4963 mir-4963 stem loop http://flybase.org/reports/FBgn0263545 miRNA_gene - - - "mir-4963, dme-mir-4963, CR43530" - CR43530 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262020 CG42831 - http://flybase.org/reports/FBgn0262020 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42831 - CG42831 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035179 CG12038 - http://flybase.org/reports/FBgn0035179 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12038 "IPR029244:FAM69, N-terminal, IPR022049:FAM69, protein-kinase domain" CG12038 27-Aug-18 DroID_v2018_08 "Drer\fam69aa, Drer\fam69b, Drer\fam69c, Drer\fam69ab" - Cele\C53D5.1 "Xtro\fam69a, Xtro\fam69b, Xtro\fam69c" "Mmus\Fam69a, Mmus\Fam69c, Mmus\Fam69b" "Hsap\FAM69C, Hsap\FAM69A, Hsap\FAM69B" FBgn0065278 l(2)SH2044 lethal (2) SH2044 http://flybase.org/reports/FBgn0065278 gene - - - "l(2)SH2044, l(2)SH2 2044" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0020261 pcm pacman http://flybase.org/reports/FBgn0020261 - protein_coding_gene exonuclease activity ; GO:0004527 | inferred from electronic annotation with InterPro:IPR004859 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR004859 "nuclear-transcribed mRNA catabolic process, exonucleolytic, 5'-3' ; GO:0034428 | inferred from mutant phenotype regulation of cytoplasmic mRNA processing body assembly ; GO:0010603 | inferred from mutant phenotype imaginal disc fusion, thorax closure ; GO:0046529 | inferred from mutant phenotype wound healing ; GO:0042060 | inferred from mutant phenotype RNA interference ; GO:0016246 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ; GO:0000184 | inferred from mutant phenotype positive regulation of imaginal disc growth ; GO:0045572 | inferred from mutant phenotype cellular response to starvation ; GO:0009267 | inferred from expression pattern nuclear-transcribed mRNA catabolic process, non-stop decay ; GO:0070481 | inferred from mutant phenotype inferred from genetic interaction with pix" cytoplasm ; GO:0005737 | inferred from direct assay cytoplasmic mRNA processing body ; GO:0000932 | inferred from direct assay "XRN1, CG3291, pcm, XRN1/pcm, Xrn1p, Pcm, Xrn1, DmXrn1" "IPR004859:Putative 5-3 exonuclease, IPR027073:5'-3' exoribonuclease, IPR029060:PIN domain-like" CG3291 27-Aug-18 DroID_v2018_08 "Drer\xrn2, Drer\xrn1" "Scer\RAT1, Scer\XRN1" "Cele\xrn-1, Cele\xrn-2" "Xtro\xrn2, Xtro\xrn1" "Mmus\Xrn2, Mmus\Xrn1" "Hsap\XRN2, Hsap\XRN1" " adult stage && oogenesis stage , adult stage | male , adult stage | female , embryonic stage | 0-8hr , embryonic stage | stage 1-7 " " nurse cell

, oocyte

,

ubiquitous " "visible,partially lethal - majority die,some die during pupal stage,viable,wound healing defective,fertile,reduced,female semi-sterile,recessive,cold sensitive,partially lethal - majority live" "mesothoracic tergum,testis,spermatozoon,egg chamber,wing,cold sensitive,posterior wing margin,metathoracic femur,cytoplasmic mRNA processing body | cold sensitive,pupal thorax,embryonic/first instar larval cuticle,cytoplasmic mRNA processing body | cold sensitiveJA27)" FBgn0028700 RfC38 Replication factor C 38kD subunit http://flybase.org/reports/FBgn0028700 protein_coding_gene DNA clamp loader activity ; GO:0003689 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000186208 DNA clamp loader activity ; GO:0003689 | contributes_to inferred from sequence or structural similarity with SGD:S000000291 leading strand elongation ; GO:0006272 | inferred from sequence or structural similarity with SGD:S000000291 sister chromatid cohesion ; GO:0007062 | inferred from sequence or structural similarity with SGD:S000000291 neurogenesis ; GO:0022008 | inferred from mutant phenotype DNA-dependent DNA replication ; GO:0006261 | inferred from biological aspect of ancestor with PANTHER:PTN000186208 microtubule associated complex ; GO:0005875 | inferred from direct assay DNA replication factor C complex ; GO:0005663 | inferred from sequence or structural similarity with SGD:S000000291 Elg1 RFC-like complex ; GO:0031391 | inferred from direct assay DNA replication factor C complex ; GO:0005663 | inferred from biological aspect of ancestor with PANTHER:PTN000186208 "l(2)rfc38, l(2)k13807, n(2)k13807, Rfc38, CG6258, BcDNA:LD06837, RfC38, DmRFC5" "IPR013748:Replication factor C, C-terminal, IPR003593:AAA+ ATPase domain, IPR008921:DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG6258 27-Aug-18 DroID_v2018_08 Drer\rfc3 Scer\RFC5 Cele\rfc-3 Xtro\rfc3 Mmus\Rfc3 Hsap\RFC3 "lethal,recessive,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell" FBgn0065814 l(2)SH0381 lethal (2) SH0381 http://flybase.org/reports/FBgn0065814 gene - - - "l(2)SH0381, l(2)SH2 0381" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0259965 Sfp35C Seminal fluid protein 35C http://flybase.org/reports/FBgn0259965 protein_coding_gene molecular_function ; GO:0003674 | no biological data available multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "Sfp35C, CG42475" - CG42475 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260278 GSd098 - http://flybase.org/reports/FBgn0260278 gene - - - GSd098 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0035027 CG3511 - http://flybase.org/reports/FBgn0035027 protein_coding_gene "peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from electronic annotation with InterPro:IPR002130, InterPro:IPR024936" "protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR002130, InterPro:IPR024936 protein peptidyl-prolyl isomerization ; GO:0000413 | inferred from electronic annotation with InterPro:IPR002130 biological_process ; GO:0008150 | no biological data available" catalytic step 2 spliceosome ; GO:0071013 | inferred from sequence or structural similarity with HGNC:28954 CG3511 "IPR001680:WD40 repeat, IPR002130:Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR024936:Cyclophilin-type peptidyl-prolyl cis-trans isomerase, IPR029000:Cyclophilin-like domain" CG3511 27-Aug-18 DroID_v2018_08 Drer\ppwd1 "Scer\CPR2, Scer\CPR5" Cele\cyn-15 Xtro\ppwd1 Mmus\Ppwd1 Hsap\PPWD1 "large body,recessive,lethal - all die before end of larval stage,some die during larval stage,viable,visible" mesothoracic tergum FBgn0041624 Or65b Odorant receptor 65b http://flybase.org/reports/FBgn0041624 protein_coding_gene olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 "CG32402, 65b, LU27.1, DOR63, Or65b" "IPR004117:Olfactory receptor, insect" CG32402 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0040347 mus81 mus81 http://flybase.org/reports/FBgn0040347 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR006166, InterPro:IPR020819 3'-flap endonuclease activity ; GO:0048257 | inferred from biological aspect of ancestor with PANTHER:PTN000335543 crossover junction endodeoxyribonuclease activity ; GO:0008821 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000335543" double-strand break repair via break-induced replication ; GO:0000727 | inferred from biological aspect of ancestor with PANTHER:PTN000335543 resolution of meiotic recombination intermediates ; GO:0000712 | inferred from biological aspect of ancestor with PANTHER:PTN000335543 intra-S DNA damage checkpoint ; GO:0031573 | inferred from biological aspect of ancestor with PANTHER:PTN000335543 mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with mei-9 replication fork processing ; GO:0031297 | inferred from biological aspect of ancestor with PANTHER:PTN000335543 DNA repair ; GO:0006281 | inferred from genetic interaction with Blm Holliday junction resolvase complex ; GO:0048476 | inferred from biological aspect of ancestor with PANTHER:PTN000335543 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000335543 "EG:BACR7A4.16, CG3026, mus81, Mus81" "IPR006166:ERCC4 domain, IPR010996:DNA polymerase beta-like, N-terminal domain, IPR011335:Restriction endonuclease type II-like" CG3026 27-Aug-18 DroID_v2018_08 Drer\mus81 Scer\MUS81 "Cele\mus-81, Cele\eme-1" Xtro\mus81 Mmus\Mus81 Hsap\MUS81 "lethal - all die before end of pupal stage,some die during pupal stage,viable,fertile,chemical sensitive" FBgn0263981 asRNA:CR43730 - http://flybase.org/reports/FBgn0263981 non_protein_coding_gene - - - CR43730 - CR43730 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0016927 smi26D smell impaired 26D http://flybase.org/reports/FBgn0016927 - gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - smi26D - - 27-Aug-18 DroID_v2018_08 - - - - - - "smell perception defective,behavior defective,recessive" FBgn0011667 Mst40 Male-specific RNA 40 http://flybase.org/reports/FBgn0011667 "FBgn0045090, FBgn0045255" gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "ORF1, bs35e07.y1, bs18c05.y1, NEST:bs35e07, NEST:bs18c05, Mst40, mst40" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0052554 CG32554 - http://flybase.org/reports/FBgn0052554 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG7871, CG32554" - CG32554 27-Aug-18 DroID_v2018_08 "Drer\cp, Drer\hephl1b" "Scer\FET3, Scer\FET5, Scer\GMC1" - Xtro\hephl1 "Mmus\Hephl1, Mmus\Cp, Mmus\Heph" "Hsap\HEPH, Hsap\CP, Hsap\HEPHL1" FBgn0001004 Fs(2)Ugr Female sterile (2) Ugra http://flybase.org/reports/FBgn0001004 - gene - eggshell chorion assembly ; GO:0007306 | inferred from mutant phenotype vitelline membrane formation involved in chorion-containing eggshell formation ; GO:0007305 | inferred from mutant phenotype - "Fs(2)Ugra, Ugra, fs(2)Ugra, Fs(2)Sz12, Fs(2)Ugr" - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile soma-dependent,dominant,female sterile" "nurse cell,egg,egg chamber,vitelline membrane,inner chorionic layer,endochorion,oocyte & cytoplasm" FBgn0060389 l(3)S133807 lethal (3) S133807 http://flybase.org/reports/FBgn0060389 gene - - - "1338/07, l(3)S133807" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0265897 lncRNA:CR44686 - http://flybase.org/reports/FBgn0265897 non_protein_coding_gene - - - CR44686 - CR44686 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0052459 CG32459 - http://flybase.org/reports/FBgn0052459 protein_coding_gene - - - "CG8220, anon-WO0140519.31, CG32459" - CG32459 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" FBgn0024709 anon-76Ca anon-76Ca http://flybase.org/reports/FBgn0024709 - gene - - - anon-76Ca - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005218 l(3)ET10 lethal Elaine Tasaka 10 http://flybase.org/reports/FBgn0005218 - gene - - - l(3)ET10 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,heat sensitive,visible" tergite FBgn0046646 anon-38D.20 anon-38D.20 http://flybase.org/reports/FBgn0046646 gene - - - "38D.20, anon-38D.20" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0053355 5SrRNA:CR33355 5SrRNA:CR33355 http://flybase.org/reports/FBgn0053355 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33355, 5SrRNA:CR33355" - CR33355 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034554 CG15227 - http://flybase.org/reports/FBgn0034554 protein_coding_gene - - - CG15227 "IPR001148:Alpha carbonic anhydrase, IPR023561:Carbonic anhydrase, alpha-class" CG15227 27-Aug-18 DroID_v2018_08 "Drer\ca6, Drer\ca8, Drer\ca16b, Drer\ca4a, Drer\ca10b, Drer\ca5a, Drer\zgc:153760, Drer\ptprga, Drer\ca9, Drer\ca7, Drer\ca12, Drer\ca4c, Drer\ca4b, Drer\ca14, Drer\car15, Drer\ca2, Drer\ca15b, Drer\ca15a, Drer\ca10a, Drer\ca15c, Drer\cahz" - "Cele\cah-5, Cele\cah-3" "Xtro\ca11, Xtro\ca3, Xtro\ca8, Xtro\ca1, Xtro\ca7, Xtro\ca10, Xtro\ca4, Xtro\LOC779564, Xtro\ca2, Xtro\ca12, Xtro\ca14, Xtro\ca6, Xtro\ca5b" "Mmus\Car1, Mmus\Car9, Mmus\Car3, Mmus\Car8, Mmus\Car2, Mmus\Car5b, Mmus\Car5a, Mmus\Car13, Mmus\Car10, Mmus\Car4, Mmus\Ptprg, Mmus\Car7, Mmus\Car15, Mmus\Car11, Mmus\Car6, Mmus\Car12, Mmus\Car14" "Hsap\CA5B, Hsap\CA11, Hsap\CA13, Hsap\CA2, Hsap\CA7, Hsap\CA12, Hsap\CA5A, Hsap\CA4, Hsap\CA6, Hsap\CA1, Hsap\CA10, Hsap\CA9, Hsap\CA8, Hsap\PTPRG, Hsap\CA3, Hsap\CA14" FBgn0024578 l(3)rL203 lethal (3) rL203 http://flybase.org/reports/FBgn0024578 - gene - - - l(3)rL203 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0065084 snmRNA:763 small non-messenger RNA 763 http://flybase.org/reports/FBgn0065084 non_protein_coding_gene - - - "Dm-763, CR33711, snmRNA:763" - CR33711 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035056 spz6 spatzle 6 http://flybase.org/reports/FBgn0035056 protein_coding_gene Toll binding ; GO:0005121 | inferred from sequence or structural similarity with spz Toll signaling pathway ; GO:0008063 | inferred from sequence or structural similarity with spz extracellular region ; GO:0005576 | inferred from sequence or structural similarity with spz "BcDNA:LP10725, CG9196, Spz6, spz6, CT26280" IPR029034:Cystine-knot cytokine CG9196 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" FBgn0040248 anon-49Db anon-49Db http://flybase.org/reports/FBgn0040248 gene - - - "11A, anon-49Db" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085641 CG41395 - http://flybase.org/reports/FBgn0085641 protein_coding_gene - - - CG41395 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267049 CG45493 - http://flybase.org/reports/FBgn0267049 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG45493 - CG45493 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0067311 CheB38b Chemosensory protein B 38b http://flybase.org/reports/FBgn0067311 protein_coding_gene lipid binding ; GO:0008289 | inferred from sequence alignment with HGNC:14537 detection of pheromone ; GO:0043695 | inferred from expression pattern sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with CheB42a extracellular space ; GO:0005615 | inferred from sequence or structural similarity with CheB42a extracellular region ; GO:0005576 | inferred from sequence model "CG9329, 38E.23, CG33321, CheB38b" "IPR006601:Uncharacterised protein family DM11, Drosophila melanogaster, IPR010512:Protein of unknown function DUF1091" CG33321 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0038054 CG5509 - http://flybase.org/reports/FBgn0038054 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG5509 - CG5509 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0267604 lncRNA:CR45942 - http://flybase.org/reports/FBgn0267604 non_protein_coding_gene - - - CR45942 - CR45942 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0053191 CG33191 - http://flybase.org/reports/FBgn0053191 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BEST:GH01761, BcDNA:GH01761, anon-WO0140519.60, CG33191" - CG33191 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0037227 TwdlV TweedleV http://flybase.org/reports/FBgn0037227 protein_coding_gene structural constituent of chitin-based cuticle ; GO:0005214 | inferred from sequence or structural similarity with TwdlD chitin-based cuticle development ; GO:0040003 | inferred from sequence or structural similarity with TwdlD proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity with TwdlD "TwdlV, CG14640" IPR004145:Domain of unknown function DUF243 CG14640 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037185 CG11367 - http://flybase.org/reports/FBgn0037185 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR015414 cellular_component ; GO:0005575 | no biological data available CG11367 "IPR015414:Transmembrane protein TMEM64, IPR032816:SNARE associated Golgi protein" CG11367 27-Aug-18 DroID_v2018_08 "Drer\tmem41b, Drer\tmem41ab, Drer\tmem41aa, Drer\tmem64" Scer\TVP38 - "Xtro\tmem64, Xtro\tmem41b" "Mmus\Tmem64, Mmus\Tmem41b, Mmus\Tmem41a" "Hsap\TMEM41A, Hsap\TMEM64, Hsap\TMEM41B" "viable,fertile" FBgn0037213 CG12581 - http://flybase.org/reports/FBgn0037213 protein_coding_gene - - - CG12581 "IPR011993:PH domain-like, IPR006020:PTB/PI domain" CG12581 27-Aug-18 DroID_v2018_08 - - Cele\R148.5 - - - "visible,partially lethal - majority die,some die during pupal stage,viable,body color defective" "trichogen cell,chaeta,supernumerary,mesothoracic tergum" FBgn0013799 Deaf1 Deformed epidermal autoregulatory factor-1 http://flybase.org/reports/FBgn0013799 "FBtr0074882, FBpp0074651" protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from sequence model with Pfam:PF01753 sequence-specific DNA binding ; GO:0043565 | inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from direct assay" "regulation of immune response ; GO:0050776 | inferred from direct assay regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from direct assay regulation of multicellular organismal development ; GO:2000026 | inferred from biological aspect of ancestor with PANTHER:PTN000812953 embryo development ending in birth or egg hatching ; GO:0009792 | inferred from mutant phenotype positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from direct assay" nucleus ; GO:0005634 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay "DEAF-1, Deaf-1, CG8567, Deaf1, DEAF1, deaf1, l(3)76BDv" "IPR000770:SAND domain, IPR002893:Zinc finger, MYND-type, IPR010919:SAND domain-like, IPR024119:Transcription factor DEAF-1" CG8567 27-Aug-18 DroID_v2018_08 "Drer\gmeb1, Drer\sp100.3, Drer\si:ch73-302a13.2, Drer\deaf1" - - "Xtro\gmeb2, Xtro\gmeb1" "Mmus\Gmeb2, Mmus\Deaf1, Mmus\Gmeb1" "Hsap\GMEB2, Hsap\DEAF1, Hsap\GMEB1" embryonic stage | early

ubiquitous " embryonic stage , embryonic stage | stage >15 " "

ubiquitous , embryonic nervous system

" "lethal - all die before end of embryonic stage,non-rescuable maternal effect,some die during embryonic stage,lethal - all die before end of pupal stage,recessive,some die during pupal stage,lethal,partially,visible,eye color defective,viable" "embryonic segment,non-rescuable maternal effect,dorsal closure embryo,heat sensitive,extended germ band embryo,wing,wing vein L3,mesothoracic bristle,scutellar bristle,eye,ommatidium,macrochaeta" DRSC22786 E -0.997237593 -0.579331667 -3.031508297 -0.737916073 -0.49978891 0.005221521 FBgn0031266 Sf3b1 Splicing factor 3b subunit 1 http://flybase.org/reports/FBgn0031266 protein_coding_gene mRNA binding ; GO:0003729 | inferred from biological aspect of ancestor with PANTHER:PTN000250426 RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:10768 "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000004901 spliceosomal complex assembly ; GO:0000245 | inferred from biological aspect of ancestor with PANTHER:PTN000250426" U2 snRNP ; GO:0005686 | inferred from sequence or structural similarity with SGD:S000004901 U12-type spliceosomal complex ; GO:0005689 | inferred from biological aspect of ancestor with PANTHER:PTN000250426 U2-type prespliceosome ; GO:0071004 | inferred from biological aspect of ancestor with PANTHER:PTN000250426 U2 snRNP ; GO:0005686 | colocalizes_with inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay "anon-21Cd, CG2807, SF3B, Sf3b1, SF3B1" "IPR011989:Armadillo-like helical, IPR015016:Splicing factor 3B subunit 1, IPR016024:Armadillo-type fold, IPR034085:TOG domain" CG2807 27-Aug-18 DroID_v2018_08 "Drer\asxl2, Drer\sf3b1" Scer\HSH155 Cele\sftb-1 Xtro\sf3b1 Mmus\Sf3b1 Hsap\SF3B1 lethal DRSC00535 IEK -1.485029124 2.2305001 -1.800193323 -4.542704503 -5.848987187 -4.354462971 FBgn0262952 mt:ND4 mitochondrial NADH-ubiquinone oxidoreductase chain 4 http://flybase.org/reports/FBgn0262952 protein_coding_gene NADH dehydrogenase (ubiquinone) activity ; GO:0008137 | inferred from electronic annotation with InterPro:IPR003918 "mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from electronic annotation with InterPro:IPR000260" - "ND4, nd4, CG34085, URF4, mt:ND4, nad4, CK00534, BEST:CK00534" "IPR000260:NADH:ubiquinone oxidoreductase chain 4, N-terminal, IPR001750:NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit, IPR003918:NADH:ubiquinone oxidoreductase" CG34085 27-Aug-18 DroID_v2018_08 Drer\ND4 - Cele\ND4 Xtro\ND4 Mmus\ND4 Hsap\ND4 FBgn0016754 sba six-banded http://flybase.org/reports/FBgn0016754 - protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001739, InterPro:IPR016177 chromatin binding ; GO:0003682 | inferred from biological aspect of ancestor with PANTHER:PTN001441501" - chromocenter ; GO:0010369 | inferred from biological aspect of ancestor with PANTHER:PTN001441501 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001441501 "AAF56201, Dm Sba, CG13598, TF125, F125, Tf125, sba, DMTF125" "IPR001739:Methyl-CpG DNA binding, IPR000313:PWWP domain, IPR016177:DNA-binding domain, IPR015943:WD40/YVTN repeat-like-containing domain" CG13598 27-Aug-18 DroID_v2018_08 Drer\mbd6 - - "Xtro\mbd6, Xtro\mbd5" "Mmus\Mbd6, Mmus\Mbd5, Mmus\Dnmt3a" "Hsap\DNMT3A, Hsap\MBD5, Hsap\MBD6" viable wing vein DRSC13643 IK -2.070235085 -1.41869342 -1.231892304 -1.499617228 -1.699100309 0.903474607 FBgn0035522 CG1273 - http://flybase.org/reports/FBgn0035522 protein_coding_gene - - - "CG1273, 1273" - CG1273 27-Aug-18 DroID_v2018_08 "Drer\fndc1, Drer\abi3bpb" - Cele\F49E10.2 - "Mmus\Abi3bp, Mmus\Fndc1" "Hsap\ABI3BP, Hsap\FNDC1" "viable,fertile" FBgn0263441 asRNA:CR43464 - http://flybase.org/reports/FBgn0263441 non_protein_coding_gene - - - CR43464 - CR43464 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0084776 W220 W220 http://flybase.org/reports/FBgn0084776 gene - - - W220 - - 27-Aug-18 DroID_v2018_08 - - - - - - eye color defective pigment cell FBgn0030870 CG6398 - http://flybase.org/reports/FBgn0030870 protein_coding_gene - establishment of glial blood-brain barrier ; GO:0060857 | NOT inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR004031 apical cortex ; GO:0045179 | inferred from direct assay septate junction ; GO:0005918 | inferred from sequence or structural similarity with sinu CG6398 IPR004031:PMP-22/EMP/MP20/Claudin superfamily CG6398 27-Aug-18 DroID_v2018_08 "Drer\cacng7a, Drer\si:ch211-150g13.3, Drer\zgc:194665, Drer\cacng5b, Drer\cacng5a, Drer\tmem178, Drer\tmem178b, Drer\si:ch211-87j1.4" - Cele\F53B3.5 Xtro\cldnd1 "Mmus\Cacng5, Mmus\Cacng7" "Hsap\CACNG7, Hsap\CACNG5, Hsap\CLDND1" viable FBgn0259860 Su(Ste):CR42429 Su(Ste):CR42429 http://flybase.org/reports/FBgn0259860 non_protein_coding_gene - - - "Su(Ste):CR42429, SuSte{}RR42263, CR42429" - CR42429 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263448 asRNA:CR43471 - http://flybase.org/reports/FBgn0263448 non_protein_coding_gene - - - CR43471 - CR43471 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0024629 l(2)k15211 lethal (2) k15211 http://flybase.org/reports/FBgn0024629 - gene - - - "152/11, l(2)k15211" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0031601 Dim1 Dim1 http://flybase.org/reports/FBgn0031601 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "neurogenesis ; GO:0022008 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000006286 spliceosomal complex assembly ; GO:0000245 | inferred from biological aspect of ancestor with PANTHER:PTN000248409 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011" small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from sequence or structural similarity with SGD:S000006286 U5 snRNP ; GO:0005682 | inferred from biological aspect of ancestor with PANTHER:PTN000248409 U4/U6 x U5 tri-snRNP complex ; GO:0046540 | inferred from biological aspect of ancestor with PANTHER:PTN000248409 precatalytic spliceosome ; GO:0071011 | inferred from direct assay "BcDNA:RE13747, U5-15kD, Dim1, CG3058" "IPR004123:Dim1 family, IPR012336:Thioredoxin-like fold" CG3058 27-Aug-18 DroID_v2018_08 "Drer\txnl4b, Drer\txnl4a" Scer\DIB1 Cele\Y54G2A.75 "Xtro\txnl4a, Xtro\txnl4b" "Mmus\Txnl4a, Mmus\Txnl4b" "Hsap\TXNL4A, Hsap\TXNL4B" "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage,viable,fertile" "embryonic/larval neuroblast,ganglion mother cell" FBgn0010324 Fs1 Female-specific 1 http://flybase.org/reports/FBgn0010324 - gene - - - Fs1 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0043895 im(1)457 im(1)457 http://flybase.org/reports/FBgn0043895 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available im(1)457 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000277 CecA2 Cecropin A2 http://flybase.org/reports/FBgn0000277 - protein_coding_gene - defense response to Gram-negative bacterium ; GO:0050829 | inferred from direct assay defense response to Gram-positive bacterium ; GO:0050830 | inferred from direct assay antibacterial humoral response ; GO:0019731 | inferred from expression pattern AND inferred from sequence or structural similarity humoral immune response ; GO:0006959 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "CecA2, CecA, Cec, CG1367, cecA2, cecA, cec, crpA2, Cec A2" "IPR020400:Cecropin, diptera, IPR000875:Cecropin" CG1367 27-Aug-18 DroID_v2018_08 - - - - - - " pupal stage , adult stage , larval stage " " adult fat body

, embryonic/larval hemocyte

" viable FBgn0040234 c12.2 c12.2 http://flybase.org/reports/FBgn0040234 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011704 ATPase activity ; GO:0016887 | inferred from electronic annotation with InterPro:IPR011704 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG12149, c12.2" "IPR002035:von Willebrand factor, type A, IPR003593:AAA+ ATPase domain, IPR011704:ATPase, dynein-related, AAA domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG12149 27-Aug-18 DroID_v2018_08 Drer\vwa8 Scer\MDN1 Cele\F11C1.5 "Xtro\vwa8, Xtro\mdn1" "Mmus\Mdn1, Mmus\Vwa8" "Hsap\VWA8, Hsap\MDN1" viable FBgn0266204 lncRNA:CR44899 - http://flybase.org/reports/FBgn0266204 non_protein_coding_gene - - - CR44899 - CR44899 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035883 CG13669 - http://flybase.org/reports/FBgn0035883 protein_coding_gene - - - CG13669 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259678 sqa spaghetti-squash activator http://flybase.org/reports/FBgn0259678 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 myosin light chain kinase activity ; GO:0004687 | inferred from biological aspect of ancestor with PANTHER:PTN002389378 protein kinase activity ; GO:0004672 | inferred from genetic interaction with Tsc1 protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from mutant phenotype" peptidyl-threonine phosphorylation ; GO:0018107 | inferred from biological aspect of ancestor with PANTHER:PTN000680267 autophagy ; GO:0006914 | inferred from mutant phenotype regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype actin filament organization ; GO:0007015 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | non-traceable author statement protein phosphorylation ; GO:0006468 | inferred from genetic interaction with Tsc1 regulation of cell shape ; GO:0008360 | inferred from mutant phenotype protein autophosphorylation ; GO:0046777 | inferred from mutant phenotype peptidyl-serine phosphorylation ; GO:0018105 | inferred from biological aspect of ancestor with PANTHER:PTN000680267 positive regulation of TOR signaling ; GO:0032008 | inferred from genetic interaction with Tsc1 intracellular ; GO:0005622 | inferred from biological aspect of ancestor with PANTHER:PTN000680267 "CG1776, CG30004, sqa, CG42347, FBgn0259678" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site, IPR020636:Calcium/calmodulin-dependent/calcium-dependent protein kinase" CG42347 27-Aug-18 DroID_v2018_08 "Drer\zgc:153952, Drer\si:dkey-240h12.4, Drer\phkg2, Drer\capsla, Drer\dscama, Drer\camk4, Drer\camk1a, Drer\uhmk1, Drer\camk1da, Drer\camk1gb, Drer\mylk4b, Drer\ttnb, Drer\pnck, Drer\si:ch211-27e6.1, Drer\mylk2, Drer\triob, Drer\camkva, Drer\pskh1, Drer\camk1b, Drer\stk17a, Drer\mylka, Drer\stk17b, Drer\stk33, Drer\si:ch73-60h1.1, Drer\camkvb, Drer\camk1ga, Drer\mylk3, Drer\phkg1a, Drer\mylkb, Drer\camkvl, Drer\trioa, Drer\dapk3, Drer\mylk4a, Drer\camk1db, Drer\capslb, Drer\dapk2a, Drer\dapk2b, Drer\dapk1, Drer\spegb" "Scer\RCK2, Scer\CMK2, Scer\KIC1, Scer\MEK1, Scer\PRR1, Scer\DUN1, Scer\CMK1, Scer\TDA1, Scer\RCK1, Scer\IKS1" "Cele\Y50D7A.3, Cele\ZC373.4, Cele\par-1, Cele\ZK524.4, Cele\unc-89" "Xtro\dscaml1, Xtro\dclk2, Xtro\capsl, Xtro\mylk, Xtro\dapk2, Xtro\stk17a, Xtro\dapk3, Xtro\pskh1, Xtro\kalrn, Xtro\mylk4, Xtro\dapk1, Xtro\pnck, Xtro\caps, Xtro\dscam, Xtro\phkg1, Xtro\phkg2, Xtro\camkv, Xtro\stk33, Xtro\mylk3, Xtro\trio, Xtro\camk1, Xtro\camk1d, Xtro\camk1g, Xtro\pskh2, Xtro\camk4" "Mmus\Dscam, Mmus\Capsl, Mmus\Phkg1, Mmus\Uhmk1, Mmus\Dapk2, Mmus\Mylk, Mmus\Pnck, Mmus\Caps2, Mmus\Dapk3, Mmus\Pskh1, Mmus\Camk1g, Mmus\Speg, Mmus\Mylk3, Mmus\Phkg2, Mmus\Camk1, Mmus\Dclk1, Mmus\Dapk1, Mmus\Stk17b, Mmus\Dscaml1, Mmus\Camkv, Mmus\Camk4, Mmus\Trio, Mmus\Camk1d, Mmus\Dclk2, Mmus\Snrk, Mmus\Stk33, Mmus\Mylk2, Mmus\Obscn, Mmus\Mylk4" "Hsap\MYLK4, Hsap\CAMK1G, Hsap\PHKG1, Hsap\CAPSL, Hsap\MYLK, Hsap\STK17A, Hsap\PHKG2, Hsap\CAMK1, Hsap\OBSCN, Hsap\CAMK1D, Hsap\CAMKV, Hsap\PSKH2, Hsap\DSCAML1, Hsap\UHMK1, Hsap\DAPK1, Hsap\CAMK4, Hsap\TRIO, Hsap\MYLK3, Hsap\MYLK2, Hsap\CAPS2, Hsap\DAPK3, Hsap\DAPK2, Hsap\ABL1, Hsap\SPEG, Hsap\PNCK, Hsap\DCLK1, Hsap\STK17B, Hsap\PSKH1, Hsap\STK33, Hsap\DSCAM, Hsap\CAPS" FBgn0019954 Nrt::wg Nrt::wg http://flybase.org/reports/FBgn0019954 - engineered_fusion_gene - - - "N-Wg, Nrt::wg" - - 27-Aug-18 DroID_v2018_08 - - - - - - "wing & macrochaetaC-765,macrochaeta,ectopic,denticle belt" FBgn0028038 l(3)S100209 lethal (3) S100209 http://flybase.org/reports/FBgn0028038 gene - - - "1002/09, l(3)S100209" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0011743 Arp53D Actin-related protein 53D http://flybase.org/reports/FBgn0011743 - protein_coding_gene structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity cytoskeleton organization ; GO:0007010 | inferred from sequence or structural similarity actin filament ; GO:0005884 | inferred from sequence or structural similarity "arp53D, CG5409, ARP53D, arp5, Actr53D, Arp53D, Arp_G, ArpG" "IPR020902:Actin/actin-like conserved site, IPR004000:Actin family" CG5409 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-241j12.3, Drer\actr1, Drer\actb2, Drer\zgc:86725, Drer\actc1a, Drer\si:ch73-187m15.4, Drer\acta2, Drer\actb1, Drer\acta1a, Drer\zgc:86709, Drer\acta1b, Drer\ankrd52b, Drer\actc1b, Drer\actr10" "Scer\ARP1, Scer\ARP8, Scer\ARP9, Scer\ACT1" "Cele\act-3, Cele\act-2, Cele\act-1, Cele\act-4" "Xtro\acta1, Xtro\actr1a, Xtro\acta2, Xtro\actc1, Xtro\actr10, Xtro\ankrd52, Xtro\act3, Xtro\actb, Xtro\actg1" "Mmus\Actc1, Mmus\Actb, Mmus\Actrt1, Mmus\Actr1a, Mmus\Actr1b, Mmus\Actrt3, Mmus\Actr10, Mmus\Actg2, Mmus\Acta1, Mmus\Actr8, Mmus\Actbl2, Mmus\Actg1, Mmus\Actl9, Mmus\Actl11, Mmus\Actl7b, Mmus\Actl7a, Mmus\Actrt2, Mmus\Actl10, Mmus\Acta2" "Hsap\POTEJ, Hsap\ACTB, Hsap\POTEE, Hsap\ACTRT1, Hsap\ACTR8, Hsap\ACTRT3, Hsap\ACTL7A, Hsap\ACTL10, Hsap\ACTR1A, Hsap\ACTC1, Hsap\ACTR1B, Hsap\ACTG1, Hsap\ACTG2, Hsap\ACTRT2, Hsap\ACTR10, Hsap\ACTBL2, Hsap\ACTL7B, Hsap\ACTL9, Hsap\ACTA2, Hsap\ACTA1, Hsap\ACTL8, Hsap\POTEI, Hsap\POTEF" " pupal stage , spermatogenesis && adult stage , adult stage | male " testis

viable FBgn0067879 Mod(Prat:bw)2-4 Mod(Prat:bw)2-4 http://flybase.org/reports/FBgn0067879 gene - - - "Mod-2-4, Mod(Prat:bw)2-4" - - 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,recessive" FBgn0042199 CG13713 - http://flybase.org/reports/FBgn0042199 protein_coding_gene - regulation of localization ; GO:0032879 | inferred from sequence or structural similarity with halo - "HL2, CG18465, CG13713" IPR007970:Protein of unknown function DUF733 CG13713 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0038804 CG10877 - http://flybase.org/reports/FBgn0038804 protein_coding_gene catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR003673 - - CG10877 "IPR003673:CoA-transferase family III, IPR023606:CoA-transferase family III domain" CG10877 27-Aug-18 DroID_v2018_08 "Drer\amacr, Drer\sugct" - Cele\C24A3.4 "Xtro\amacr, Xtro\sugct" "Mmus\Amacr, Mmus\Sugct" "Hsap\SUGCT, Hsap\AMACR" viable FBgn0037698 CG16779 - http://flybase.org/reports/FBgn0037698 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN001043031 transcription regulatory region DNA binding ; GO:0044212 | inferred from biological aspect of ancestor with PANTHER:PTN001043031 transcription factor binding ; GO:0008134 | inferred from biological aspect of ancestor with PANTHER:PTN001043031" regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from biological aspect of ancestor with PANTHER:PTN001043031 transcription factor complex ; GO:0005667 | inferred from biological aspect of ancestor with PANTHER:PTN001043031 histone deacetylase complex ; GO:0000118 | inferred from biological aspect of ancestor with PANTHER:PTN000412838 CG16779 "IPR000949:ELM2 domain, IPR001005:SANT/Myb domain, IPR013087:Zinc finger C2H2-type, IPR009057:Homeobox domain-like, IPR017884:SANT domain, IPR011990:Tetratricopeptide-like helical domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG16779 27-Aug-18 DroID_v2018_08 "Drer\LOC100535969, Drer\si:dkey-19b23.10, Drer\elmsan1b, Drer\elmsan1a" - "Cele\Y105C5A.1, Cele\saeg-1, Cele\Y73B3A.13, Cele\F28F8.7" "Xtro\elmsan1, Xtro\trerf1" "Mmus\Elmsan1, Mmus\Zfp541, Mmus\Trerf1" "Hsap\ELMSAN1, Hsap\ZNF541, Hsap\TRERF1" viable DRSC15153 K -0.330473416 -1.147200459 0.047791599 -1.104240657 -1.326210351 -3.034568446 FBgn0262708 ifm(2)RS1 - http://flybase.org/reports/FBgn0262708 gene - flight ; GO:0060361 | inferred from mutant phenotype adult somatic muscle development ; GO:0007527 | inferred from mutant phenotype - ifm(2)RS1 - - 27-Aug-18 DroID_v2018_08 - - - - - - "flightless,recessive" dorsal medial muscle FBgn0036089 CG14151 - http://flybase.org/reports/FBgn0036089 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14151 IPR031720:Protein of unknown function DUF4728 CG14151 27-Aug-18 DroID_v2018_08 - - Cele\sre-55 - - - "viable,body color defective" mesothoracic tergum DRSC10153 E 0.056923002 -1.327908386 2.299723351 -0.242262893 0.933765552 0.178061266 FBgn0031765 CG9109 - http://flybase.org/reports/FBgn0031765 protein_coding_gene "transferase activity, transferring glycosyl groups ; GO:0016757 | inferred from electronic annotation with InterPro:IPR003378" - membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR003378 "CG9109, dC1GalT9" IPR003378:Fringe-like CG9109 27-Aug-18 DroID_v2018_08 "Drer\b3glcta, Drer\b3glctb" - Cele\ZC250.2 Xtro\b3glct Mmus\B3glct Hsap\B3GLCT "lethal,body color defective" mesothoracic tergum FBgn0259465 C495 - http://flybase.org/reports/FBgn0259465 gene - - - C495 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing vein,wing vein L4" FBgn0039296 CG10420 - http://flybase.org/reports/FBgn0039296 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "SRP-dependent cotranslational protein targeting to membrane, translocation ; GO:0006616 | inferred from sequence or structural similarity with UniProtKB:Q08199" endoplasmic reticulum ; GO:0005783 | inferred from sequence or structural similarity with UniProtKB:Q08199 endomembrane system ; GO:0012505 | inferred from direct assay endoplasmic reticulum ; GO:0005783 | inferred from biological aspect of ancestor with PANTHER:PTN001062495 "CG10420, SIL1" "IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold" CG10420 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-195b11.7, Drer\hspbp1" "Scer\SIL1, Scer\FES1" - "Xtro\sil1, Xtro\hspbp1" "Mmus\Sil1, Mmus\Hspbp1" "Hsap\SIL1, Hsap\HSPBP1" viable DRSC14242 E 0.528342786 0.257767637 1.952200948 1.30461057 -0.426873822 0.774138065 FBgn0063419 l(3)3450-D lethal (3) 3450-D http://flybase.org/reports/FBgn0063419 gene - - - l(3)3450-D - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0062652 EP374 EP374 http://flybase.org/reports/FBgn0062652 gene - - - "EP(3)0374, EP374" - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing,scutellum,adult thorax,dorsal" FBgn0034583 CG10527 - http://flybase.org/reports/FBgn0034583 protein_coding_gene farnesoic acid O-methyltransferase activity ; GO:0019010 | NOT inferred from direct assay - cytoplasm ; GO:0005737 | inferred from direct assay "CG10527, FAMeT" "IPR006616:DM9 repeat, IPR024518:Domain of unknown function DUF3421, IPR022041:Farnesoic acid O-methyl transferase" CG10527 27-Aug-18 DroID_v2018_08 - - - - - - "short lived,viable,chemical resistant" FBgn0061080 l(3)S014310b lethal (3) S014310b http://flybase.org/reports/FBgn0061080 gene - - - "0143/10, l(3)S014310b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0003905 ty tiny http://flybase.org/reports/FBgn0003905 - gene - oogenesis ; GO:0048477 | traceable author statement - "l(1)4-103, ty" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,visible,female sterile" "macrochaeta & thorax,eye" FBgn0259753 ms(2)Fra-4 - http://flybase.org/reports/FBgn0259753 gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype chromosome organization ; GO:0051276 | inferred from mutant phenotype - ms(2)Fra-4 - - 27-Aug-18 DroID_v2018_08 - - - - - - male sterile "Y chromosome loop,Nebenkern,spermatid,nucleus & spermatid,spermatozoon" FBgn0045500 Gr22b Gustatory receptor 22b http://flybase.org/reports/FBgn0045500 protein_coding_gene sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 taste receptor activity ; GO:0008527 | inferred from sequence or structural similarity with Gr5a olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 detection of chemical stimulus involved in sensory perception of taste ; GO:0050912 | inferred from sequence or structural similarity with Gr5a response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 integral component of membrane ; GO:0016021 | inferred from sequence model dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 "Gr22bP, Gr2940.4, CR31931, CG31931, Gr22b, GR22b" IPR013604:7TM chemoreceptor CG31931 27-Aug-18 DroID_v2018_08 - - "Cele\gur-3, Cele\lite-1" - - - "partially lethal - majority die,some die during pupal stage" FBgn0267568 asRNA:CR45908 - http://flybase.org/reports/FBgn0267568 non_protein_coding_gene - - - CR45908 - CR45908 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001719 l(1)ESHS40 lethal (1) ESHS40 http://flybase.org/reports/FBgn0001719 - gene - - - l(1)ESHS40 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0031422 PIG-Wa Phosphatidylinositol glycan anchor biosynthesis class W a http://flybase.org/reports/FBgn0031422 protein_coding_gene "transferase activity, transferring acyl groups ; GO:0016746 | inferred from electronic annotation with InterPro:IPR009447" GPI anchor biosynthetic process ; GO:0006506 | inferred from electronic annotation with InterPro:IPR009447 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR009447 "CG9870, PIG-Wa, PIG-W" IPR009447:GWT1 CG9870 27-Aug-18 DroID_v2018_08 Drer\pigw Scer\GWT1 Cele\hpo-20 Xtro\pigw Mmus\Pigw Hsap\PIGW viable FBgn0264995 lncRNA:CR44146 - http://flybase.org/reports/FBgn0264995 non_protein_coding_gene - - - CR44146 - CR44146 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038114 CG11670 - http://flybase.org/reports/FBgn0038114 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "SP27, CG11670" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG11670 27-Aug-18 DroID_v2018_08 - - "Cele\svh-1, Cele\try-3" - - Hsap\MASP1 "viable,fertile" FBgn0261991 CG42809 - http://flybase.org/reports/FBgn0261991 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42809, CG16849" - CG42809 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038251 Hexim Hexamethylene bisacetamide inducible http://flybase.org/reports/FBgn0038251 protein_coding_gene cyclin-dependent protein serine/threonine kinase inhibitor activity ; GO:0004861 | inferred from electronic annotation with InterPro:IPR024872 7SK snRNA binding ; GO:0097322 | inferred from direct assay negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from electronic annotation with InterPro:IPR024872 cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR024872 nucleus ; GO:0005634 | inferred from direct assay "Hexim, dHEXIM, CG3508" IPR024872:HEXIM CG3508 27-Aug-18 DroID_v2018_08 Drer\hexim1 - - Xtro\hexim1 "Mmus\Hexim1, Mmus\Hexim2" "Hsap\HEXIM1, Hsap\HEXIM2" "lethal,visible,lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of second instar larval stage,some die during second instar larval stage,viable,fertile" "leg,wing,eye" FBgn0028870 CG4691 - http://flybase.org/reports/FBgn0028870 protein_coding_gene - - - "BG:DS06874.1, anon-WO0140519.47, CG4691" "IPR006611:Protein of unknown function DUF1431, cysteine-rich, Drosophila" CG4691 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0266283 ddt double double trouble http://flybase.org/reports/FBgn0266283 gene - - - ddt - - 27-Aug-18 DroID_v2018_08 - - - - - - "chemical sensitive,somatic clone,lethal,conditional" "eye,somatic clone,conditional" FBgn0052010 CR32010 - http://flybase.org/reports/FBgn0052010 pseudogene_attribute - - - "CG32010, CR32010" - CR32010 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0016779 anon-77Bc anon-77Bc http://flybase.org/reports/FBgn0016779 - gene - - - "D, anon-77Bc" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004123 l(2)43Bb lethal (2) 43Bb http://flybase.org/reports/FBgn0004123 - gene - - - "43Bb, l(2)04614, l(2)43Bb" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0020269 mspo M-spondin http://flybase.org/reports/FBgn0020269 - protein_coding_gene - regulation of myoblast fusion ; GO:1901739 | inferred from mutant phenotype - "CT28539, CG10145, mspo, Mspo, m-spo" "IPR000884:Thrombospondin type-1 (TSP1) repeat, IPR009465:Spondin, N-terminal" CG10145 27-Aug-18 DroID_v2018_08 "Drer\spon2a, Drer\spon1a, Drer\spon2b, Drer\spon1b" - Cele\spon-1 Xtro\spon2 "Mmus\Spon1, Mmus\Spon2" "Hsap\SPON2, Hsap\SPON1" "viable,fertile" "dorsal acute muscle 1,nucleus | supernumerary,nucleuseve.eme" FBgn0027592 MED15 Mediator complex subunit 15 http://flybase.org/reports/FBgn0027592 - protein_coding_gene RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from sequence or structural similarity RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from sequence or structural similarity with UniProtKB:Q9W0P8 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from electronic annotation with InterPro:IPR019087 ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype transcription from RNA polymerase II promoter ; GO:0006366 | inferred from sequence or structural similarity with UniProtKB:Q9W0P8 transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity mediator complex ; GO:0016592 | inferred from sequence or structural similarity mediator complex ; GO:0016592 | inferred from sequence or structural similarity with UniProtKB:Q9W0P8 "Arc105, Med9/ARC105, dARC105, CG4184, BcDNA:GH03922, MED15, Med15, med15" "IPR019087:Mediator of RNA polymerase II transcription subunit 15, IPR003101:Coactivator CBP, KIX domain" CG4184 27-Aug-18 DroID_v2018_08 Drer\med15 - - Xtro\LOC100493634 Mmus\Med15 Hsap\MED15 "visible,increased cell death,lethal - all die before end of pupal stage,some die during pupal stage" "wing margin,wing,wing vein L2,distal,wing sensillum,ectopic,wing disc" DRSC00267 IK 0.93621912 1.842426673 0.26150271 1.259472352 0.93466722 2.099781538 FBgn0031164 CG1724 - http://flybase.org/reports/FBgn0031164 protein_coding_gene protein channel activity ; GO:0015266 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000050380 P-P-bond-hydrolysis-driven protein transmembrane transporter activity ; GO:0015450 | inferred from sequence or structural similarity with UniProtKB:O60830 protein import into mitochondrial matrix ; GO:0030150 | inferred from biological aspect of ancestor with PANTHER:PTN000050380 protein targeting to mitochondrion ; GO:0006626 | inferred from sequence or structural similarity with UniProtKB:O60830 mitochondrial inner membrane presequence translocase complex ; GO:0005744 | inferred from biological aspect of ancestor with PANTHER:PTN000050380 integral component of mitochondrial inner membrane ; GO:0031305 | inferred from biological aspect of ancestor with PANTHER:PTN000050380 mitochondrial inner membrane presequence translocase complex ; GO:0005744 | inferred from sequence or structural similarity with UniProtKB:O60830 "BcDNA:AT13347, CG1724" IPR003397:Mitochondrial inner membrane translocase subunit Tim17/Tim22/Tim23/peroxisomal protein PMP24 CG1724 27-Aug-18 DroID_v2018_08 "Drer\timm17a, Drer\timm17b" Scer\TIM17 "Cele\E04A4.5, Cele\D2096.1, Cele\C47G2.3" Xtro\timm17a "Mmus\Timm17b, Mmus\Timm17a" "Hsap\TIMM17B, Hsap\TIMM17A" viable FBgn0002135 l(2)K224 lethal (2) K224 http://flybase.org/reports/FBgn0002135 - gene - - - l(2)K224 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0032014 CG7840 - http://flybase.org/reports/FBgn0032014 protein_coding_gene "oxidoreductase activity, acting on the CH-CH group of donors ; GO:0016627 | inferred from electronic annotation with InterPro:IPR001104" dolichol metabolic process ; GO:0019348 | inferred from sequence or structural similarity with UniProtKB:Q9H8P0 polyprenol catabolic process ; GO:0016095 | inferred from sequence or structural similarity with UniProtKB:Q9H8P0 dolichol-linked oligosaccharide biosynthetic process ; GO:0006488 | inferred from sequence or structural similarity with UniProtKB:Q9H8P0 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR001104 cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR001104 "cg7840, CG7840" "IPR001104:3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal" CG7840 27-Aug-18 DroID_v2018_08 Drer\srd5a3 Scer\DFG10 Cele\B0024.13 Xtro\srd5a3 Mmus\Srd5a3 Hsap\SRD5A3 viable FBgn0024251 bbx bobby sox http://flybase.org/reports/FBgn0024251 "FBgn0014083, FBgn0052527, FBtr0077200, FBpp0076899, FBtr0077201, FBpp0076900, FBtr0077202, FBpp0076901" protein_coding_gene - - - "tu2, CG32527, anon-19Fb, CG1414, bbx" IPR009071:High mobility group box domain CG1414 27-Aug-18 DroID_v2018_08 "Drer\cica, Drer\cicb, Drer\sox21b" - - - "Mmus\Cic, Mmus\Bbx" "Hsap\BBX, Hsap\SOX14, Hsap\SOX21" "viable,fertile" embryonic/larval hemocyte | third instar larval stage FBgn0265165 lncRNA:CR44234 - http://flybase.org/reports/FBgn0265165 non_protein_coding_gene - - - "CR44234, lincRNA.762" - CR44234 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262412 mir-1008 mir-1008 stem loop http://flybase.org/reports/FBgn0262412 miRNA_gene - - - "mir-1008, dme-mir-1008, CR42957, miR-1008, dme-miR-1008" - CR42957 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0000020 abt abnormal tergites http://flybase.org/reports/FBgn0000020 - gene - - - abt - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,viable,male,male sterile,partially,recessive,male semi-sterile,body color defective" "adult abdomen & microchaeta,eye,ommatidium,wing,wing vein,tergite,adult abdomen" FBgn0043554 Su(ro[DOM])519 Su(ro[DOM])519 http://flybase.org/reports/FBgn0043554 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with ro cellular_component ; GO:0005575 | no biological data available Su(ro[DOM])519 - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible,dominant" eye FBgn0044049 Ilp4 Insulin-like peptide 4 http://flybase.org/reports/FBgn0044049 protein_coding_gene hormone activity ; GO:0005179 | inferred from electronic annotation with InterPro:IPR016179 insulin receptor binding ; GO:0005158 | inferred from sequence or structural similarity with HGNC:6081 larval feeding behavior ; GO:0030536 | inferred from mutant phenotype insulin receptor signaling pathway ; GO:0008286 | inferred from sequence or structural similarity with HGNC:6081 extracellular space ; GO:0005615 | inferred from sequence or structural similarity with HGNC:6081 "mes3, CG6736, dilp4, dilp, Mes3, anon-EST:CLB3, dilp-4, DILP, Dilp, Dilp 4, Dirlp, DILP4, A, BcDNA:RE27042, Ilp4, Ilp, ilp4, Ilp-4, Dilp4, DILP-4, dILP4" "IPR016179:Insulin-like, IPR022352:Insulin family, IPR022353:Insulin, conserved site" CG6736 27-Aug-18 DroID_v2018_08 "Drer\insl3, Drer\insl5b" - - - Mmus\Insl3 Hsap\INSL3 " embryonic stage | stage >5 , larval stage | third instar , embryonic stage | cellular blastoderm , embryonic stage | stage 12-16 , embryonic stage | stage 2-12 , embryonic stage | stage 5 " " mesoderm

, embryonic/larval midgut

, mesoderm anlage

, anterior midgut proper primordium

" "feeding behavior defective,large body,viable" embryonic/larval neuroblast FBgn0034911 GlyT - http://flybase.org/reports/FBgn0034911 protein_coding_gene neurotransmitter:sodium symporter activity ; GO:0005328 | inferred from electronic annotation with InterPro:IPR000175 neurotransmitter transporter activity ; GO:0005326 | inferred from sequence or structural similarity with DAT glycine:sodium symporter activity ; GO:0015375 | inferred from sequence model transporter activity ; GO:0005215 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 glycine transport ; GO:0015816 | inferred from sequence model neurotransmitter transport ; GO:0006836 | inferred from sequence or structural similarity with DAT transport ; GO:0006810 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 integral component of membrane ; GO:0016021 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 CG5549 IPR000175:Sodium:neurotransmitter symporter CG5549 27-Aug-18 DroID_v2018_08 "Drer\slc6a6b, Drer\slc6a9, Drer\slc6a1a, Drer\slc6a16b, Drer\si:ch211-132b12.1, Drer\slc6a15, Drer\slc6a13, Drer\slc6a8, Drer\si:ch211-132b12.6, Drer\si:ch211-132b12.2, Drer\slc6a4b, Drer\slc6a17, Drer\slc6a1l, Drer\slc6a19a.1, Drer\slc6a2, Drer\slc6a11a, Drer\slc6a19b, Drer\slc6a16a, Drer\si:ch211-117c9.5, Drer\slc6a13, Drer\slc6a6a, Drer\si:ch211-132b12.3, Drer\zgc:174946, Drer\slc6a1b, Drer\slc6a13l, Drer\slc6a4a, Drer\zgc:158225, Drer\slc6a14, Drer\slc6a5, Drer\slc6a18" - "Cele\dat-1, Cele\snf-2, Cele\F56F4.3, Cele\snf-6, Cele\snf-7, Cele\mod-5, Cele\snf-9, Cele\snf-11, Cele\C09E8.1, Cele\snf-3, Cele\snf-5" "Xtro\slc6a13, Xtro\slc6a19, Xtro\slc6a2, Xtro\slc6a6, Xtro\slc6a17, Xtro\slc6a14.2, Xtro\slc6a15, Xtro\slc6a12, Xtro\slc6a8, Xtro\LOC100127682, Xtro\slc6a7, Xtro\slc6a1, Xtro\slc6a5, Xtro\slc6a16, Xtro\slc6a3, Xtro\slc6a4, Xtro\slc6a9" "Mmus\Slc6a1, Mmus\Slc6a4, Mmus\Slc6a8, Mmus\Slc6a13, Mmus\Slc6a2, Mmus\Slc6a14, Mmus\Slc6a11, Mmus\Slc6a6, Mmus\Slc6a7, Mmus\Slc6a5, Mmus\Slc6a9, Mmus\Slc6a15, Mmus\Slc6a20a, Mmus\Slc6a3, Mmus\Slc6a12, Mmus\Slc6a18, Mmus\Slc6a17, Mmus\Slc6a20b, Mmus\Slc6a19" "Hsap\SLC6A18, Hsap\SLC6A19, Hsap\SLC6A3, Hsap\SLC6A1, Hsap\SLC6A8, Hsap\SLC6A9, Hsap\SLC6A4, Hsap\SLC6A12, Hsap\SLC6A11, Hsap\SLC6A15, Hsap\SLC6A2, Hsap\SLC6A17, Hsap\SLC6A13, Hsap\SLC6A7, Hsap\SLC6A6, Hsap\SLC6A20, Hsap\SLC6A5, Hsap\SLC6A14" "viable,visible" trichogen cell FBgn0027136 l(3)88EFa lethal (3) 88EFa http://flybase.org/reports/FBgn0027136 - gene - - - l(3)88EFa - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0020895 Su(osk)G71 Suppressor of oskar G71 http://flybase.org/reports/FBgn0020895 - gene - - - "G71, Su(osk)G71" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0069423 JJF028 JJF028 http://flybase.org/reports/FBgn0069423 gene - - - JJF028 - - 27-Aug-18 DroID_v2018_08 - - - - - - stress response defective FBgn0035358 CG14949 - http://flybase.org/reports/FBgn0035358 protein_coding_gene - - - CG14949 - CG14949 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262025 lncRNA:CR42836 - http://flybase.org/reports/FBgn0262025 non_protein_coding_gene - - - "CR42836, lincRNA.818" - CR42836 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0024998 CG2685 - http://flybase.org/reports/FBgn0024998 - protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:16461 "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 mRNA cis splicing, via spliceosome ; GO:0045292 | inferred from biological aspect of ancestor with PANTHER:PTN000331938" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay "EG:100G10.1, CG2685" IPR019007:WW domain binding protein 11 CG2685 27-Aug-18 DroID_v2018_08 Drer\wbp11 - "Cele\F33H1.3, Cele\C31G12.4" Xtro\wbp11 Mmus\Wbp11 Hsap\WBP11 "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum DRSC18463 E -1.496589167 -0.933106189 1.688498094 -1.846632426 0.961629419 1.147872764 FBgn0063391 snoRNA:U14:30Eb snoRNA:U14:30Eb http://flybase.org/reports/FBgn0063391 snoRNA_gene - - - "Dm-396, U14snoRNA, snoRNA:U14:b, CR32876, snoRNA:U14:30Eb" - CR32876 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001458 l(1)7Dl lethal (1) 7Dl http://flybase.org/reports/FBgn0001458 - gene - - - l(1)7Dl - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage,maternal effect" "ovariole,germline clone,egg,maternal effect" FBgn0082933 snoRNA:Me28S-G1083c snoRNA:Me28S-G1083c http://flybase.org/reports/FBgn0082933 snoRNA_gene rRNA 2'-O-ribose methylation guide activity ; GO:0030562 | inferred from sequence model rRNA 2'-O-methylation ; GO:0000451 | inferred from sequence model nucleolus ; GO:0005730 | inferred from direct assay "snoRNA:Me28S-G1083c, Me28S-Gm1083c, CR34564, DmSnR60, DmSnR60c" - CR34564 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266699 asRNA:CR45189 - http://flybase.org/reports/FBgn0266699 non_protein_coding_gene - - - CR45189 - CR45189 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0029582 CG3729 - http://flybase.org/reports/FBgn0029582 protein_coding_gene - - - CG3729 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040545 CG14702 - http://flybase.org/reports/FBgn0040545 protein_coding_gene - - - CG14702 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0046667 anon-38C.3 anon-38C.3 http://flybase.org/reports/FBgn0046667 gene - - - "38C.3, anon-38C.3" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000143 at arctus oculus http://flybase.org/reports/FBgn0000143 - gene - - - at - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive,viable,good,fertile" eye FBgn0051826 CG31826 - http://flybase.org/reports/FBgn0051826 protein_coding_gene transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR001071 transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR001071 intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR001071 "CG13241, BG:DS09217.6, CG31826" "IPR001071:Cellular retinaldehyde binding/alpha-tocopherol transport, IPR001251:CRAL-TRIO lipid binding domain, IPR011074:CRAL/TRIO, N-terminal domain" CG31826 27-Aug-18 DroID_v2018_08 "Drer\ttpa, Drer\sec14l7, Drer\rlbp1a, Drer\sec14l8, Drer\ttpal, Drer\clvs2" "Scer\SFH5, Scer\SEC14, Scer\YKL091C" - "Xtro\mospd2, Xtro\sec14l5, Xtro\clvs2, Xtro\ttpa, Xtro\rlbp1, Xtro\clvs1, Xtro\ttpal, Xtro\sec14l1, Xtro\sec14l3" "Mmus\Sec14l2, Mmus\Ttpal, Mmus\Sec14l1, Mmus\Sec14l3, Mmus\Rlbp1, Mmus\Sec14l4, Mmus\Ttpa, Mmus\Clvs2, Mmus\Sec14l5, Mmus\Clvs1" "Hsap\RLBP1, Hsap\CLVS1, Hsap\CLVS2, Hsap\TTPAL, Hsap\SEC14L1, Hsap\SEC14L4, Hsap\TTPA, Hsap\SEC14L6, Hsap\SEC14L3, Hsap\SEC14L5, Hsap\SEC14L2" viable FBgn0036827 CG6843 - http://flybase.org/reports/FBgn0036827 protein_coding_gene molecular_function ; GO:0003674 | no biological data available "negative regulation of transcription, DNA-templated ; GO:0045892 | inferred from sequence or structural similarity with HGNC:24217" nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:24217 CG6843 "IPR019339:CBF1-interacting co-repressor CIR, N-terminal domain" CG6843 27-Aug-18 DroID_v2018_08 Drer\rp9 - Cele\cir-1 Xtro\cir1 "Mmus\Cir1, Mmus\Rp9" "Hsap\CIR1, Hsap\RP9" FBgn0264510 lncRNA:CR43909 - http://flybase.org/reports/FBgn0264510 non_protein_coding_gene - - - CR43909 - CR43909 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0045859 csn casanova http://flybase.org/reports/FBgn0045859 gene - - - "ms(3)HB156, csn" - - 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,female fertile,viable,recessive" FBgn0284421 Psn Presenilin http://flybase.org/reports/FBgn0284421 protein_coding_gene "aspartic-type endopeptidase activity ; GO:0004190 | inferred from electronic annotation with InterPro:IPR001108, InterPro:IPR006639 protein homodimerization activity ; GO:0042803 | inferred from physical interaction with Psn" intracellular signal transduction ; GO:0035556 | inferred from electronic annotation with InterPro:IPR001493 protein processing ; GO:0016485 | inferred from electronic annotation with InterPro:IPR001108 Notch signaling pathway ; GO:0007219 | inferred from mutant phenotype Notch receptor processing ; GO:0007220 | inferred from mutant phenotype copper ion import ; GO:0015677 | inferred from mutant phenotype single organismal cell-cell adhesion ; GO:0016337 | inferred from mutant phenotype membrane protein ectodomain proteolysis ; GO:0006509 | traceable author statement regulation of Notch signaling pathway ; GO:0008593 | inferred from mutant phenotype short-term memory ; GO:0007614 | inferred from mutant phenotype lateral inhibition ; GO:0046331 | inferred from mutant phenotype regulation of heart rate ; GO:0002027 | inferred from mutant phenotype Notch receptor processing ; GO:0007220 | traceable author statement neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype associative learning ; GO:0008306 | inferred from mutant phenotype cytoskeleton organization ; GO:0007010 | inferred from mutant phenotype wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from mutant phenotype "recycling endosome ; GO:0055037 | inferred from direct assay apical plasma membrane ; GO:0016324 | inferred from direct assay gamma-secretase complex ; GO:0070765 | inferred from physical interaction with aph-1, nct, pen-2 cytoplasm ; GO:0005737 | inferred from direct assay late endosome ; GO:0005770 | inferred from direct assay cell cortex ; GO:0005938 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from direct assay" "CG18803, Psn, psn, CG5868, PS, DPsn, Dps, PS1, DPS, pres, l(3)77CDb, DmPS, DrosPS, dPsn, PSN, 493/14, 0493/14, l(3)S049314, l(3)S049314a, 0480/15, l(3)S048015a" "IPR001493:Peptidase A22A, presenilin 2, IPR001108:Peptidase A22A, presenilin, IPR006639:Presenilin/signal peptide peptidase" CG18803 27-Aug-18 DroID_v2018_08 "Drer\psen2, Drer\psen1" - "Cele\sel-12, Cele\spe-4, Cele\hop-1" "Xtro\psen2, Xtro\psen1" "Mmus\Psen2, Mmus\Psen1" "Hsap\PSEN1, Hsap\PSEN2" "lethal,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0259186 Ir60c Ionotropic receptor 60c http://flybase.org/reports/FBgn0259186 pseudogene_attribute - - - "CG13582, DmelIR60c, CG42290, Ir60c, IR60c, CR42290" - CR42290 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0015001 iotaTry iotaTrypsin http://flybase.org/reports/FBgn0015001 - protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "143775_at, SP129, CG7754, iotaTry" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG7754 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-165b19.9, Drer\zgc:55888, Drer\si:ch211-165b19.8, Drer\LOC562139, Drer\zgc:112160, Drer\ctrl" - "Cele\svh-1, Cele\try-1" - "Mmus\Prss36, Mmus\Klk14, Mmus\Mcpt8, Mmus\Prss55, Mmus\Prss53" "Hsap\KLK14, Hsap\PRSS53, Hsap\PRSS36, Hsap\GZMB" viable FBgn0085334 CG34305 - http://flybase.org/reports/FBgn0085334 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34305 - CG34305 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0261639 CR42722 - http://flybase.org/reports/FBgn0261639 pseudogene_attribute - - - CR42722 - CR42722 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051390 MED7 Mediator complex subunit 7 http://flybase.org/reports/FBgn0051390 protein_coding_gene RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from sequence or structural similarity protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9W5P1 RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from electronic annotation with InterPro:IPR009244 transcription from RNA polymerase II promoter ; GO:0006366 | inferred by curator from GO:0001104 transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity mediator complex ; GO:0016592 | inferred from biological aspect of ancestor with PANTHER:PTN000484466 mediator complex ; GO:0016592 | inferred from sequence or structural similarity mediator complex ; GO:0016592 | inferred by curator from GO:0001104 core mediator complex ; GO:0070847 | inferred from biological aspect of ancestor with PANTHER:PTN000484466 "Med7, dMED7, dTRAP34, CG6529, CG31390, MED7" "IPR009244:Mediator complex, subunit Med7" CG31390 27-Aug-18 DroID_v2018_08 Drer\med7 Scer\MED7 Cele\let-49 Xtro\med7 Mmus\Med7 Hsap\MED7 "lethal - all die before end of pupal stage,some die during pupal stage" DRSC16059 IEK -2.266768988 1.656760997 -2.911276715 0.498031782 2.355447936 3.348135134 FBgn0000377 crn crooked neck http://flybase.org/reports/FBgn0000377 "FBgn0004044, FBgn0042162" protein_coding_gene RNA binding ; GO:0003723 | inferred from sequence or structural similarity with HGNC:15762 "axon ensheathment ; GO:0008366 | inferred from mutant phenotype regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype centrosome duplication ; GO:0051298 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 oenocyte development ; GO:0007438 | inferred from mutant phenotype Malpighian tubule morphogenesis ; GO:0007443 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype glial cell migration ; GO:0008347 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay mitotic spindle ; GO:0072686 | inferred from direct assay nuclear speck ; GO:0016607 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay nucleus ; GO:0005634 | inferred by curator from GO:0000381 nucleus ; GO:0005634 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay "CG3193, Crn, EG:30B8.1, yok, l30, RC63, l(1)2, l(1)CRN, N10, N5, 62D9.a, crn, CG18842, l(1)crn, l(1)N7, l(1)2Fa" "IPR003107:HAT (Half-A-TPR) repeat, IPR013026:Tetratricopeptide repeat-containing domain, IPR011990:Tetratricopeptide-like helical domain" CG3193 27-Aug-18 DroID_v2018_08 Drer\crnkl1 Scer\CLF1 Cele\M03F8.3 Xtro\crnkl1 Mmus\Crnkl1 Hsap\CRNKL1 " embryonic stage , adult stage | female "

ubiquitous "some die during embryonic stage,recessive,lethal - all die before end of embryonic stage,wild-type,lethal,germline clone,dominant,neuroanatomy defective,cell lethal,viable,lethal - all die before end of pupal stage,some die during pupal stage" "glial cell,embryo,Malpighian tubule,embryonic Malpighian tubule,embryonic/larval neuroblast,ganglion mother cell,embryonic/larval glial cell,peripheral glial cell,embryonic/larval oenocyte precursor" DRSC18184 EK -0.735668429 0.757430033 2.329051917 0.656615062 -1.877734444 0.163732937 FBgn0026713 l(1)G0007 lethal (1) G0007 http://flybase.org/reports/FBgn0026713 "FBgn0026709, FBgn0027309, FBgn0028281, FBgn0029047, FBgn0030546, FBgn0030550, FBgn0040139, FBgn0040178, FBgn0040194, FBgn0044447, FBgn0044450, FBgn0052604" protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002464, InterPro:IPR011545 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR002464, InterPro:IPR011545 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from sequence or structural similarity with SGD:S000001794 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000433338" "inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD:S000001794" spliceosomal complex ; GO:0005681 | inferred from sequence or structural similarity with SGD:S000001794 spliceosomal complex ; GO:0005681 | inferred from biological aspect of ancestor with PANTHER:PTN000433947 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000433338 "l(1)G0476, CG1405, CG32604, cg1405, l(1)G0103, l(1)G0176, l(1)G0491, l(1)G0308, l(1)G0028, l(1)G0416, EP784, EP764, CG1375, l(1)G0007, lethal (1) G0007, Prp16, prp16" "IPR001650:Helicase, C-terminal, IPR002464:DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site, IPR007502:Helicase-associated domain, IPR011709:Domain of unknown function DUF1605, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR011545:DEAD/DEAH box helicase domain" CG32604 27-Aug-18 DroID_v2018_08 "Drer\dhx32a, Drer\dhx38, Drer\zgc:158828, Drer\dhx15, Drer\dhx8, Drer\dhx16, Drer\dhx33, Drer\dhx32b" "Scer\PRP16, Scer\DHR2, Scer\PRP43, Scer\PRP2, Scer\PRP22" "Cele\ddx-35, Cele\let-355, Cele\ddx-15, Cele\mog-5, Cele\mog-1, Cele\mog-4" "Xtro\dhx16, Xtro\dhx15, Xtro\dhx35, Xtro\dhx33, Xtro\dhx38, Xtro\dhx8" "Mmus\Dhx8, Mmus\Dhx16, Mmus\Dhx33, Mmus\Dhx35, Mmus\Dhx38, Mmus\Dhx32, Mmus\Dqx1, Mmus\Dhx15" "Hsap\DHX8, Hsap\DHX32, Hsap\DHX16, Hsap\DHX38, Hsap\DHX33, Hsap\DQX1, Hsap\DHX35, Hsap\DHX15" "behavior defective,recessive,long lived,female limited,starvation stress response defective,temperature response defective,gravitaxis defective,male limited,viable,fertile,lethal,neuroanatomy defective,partially lethal - majority die,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of P-stage,some die during pharate adult stage,lethal - all die before end of embryonic stage,some die during embryonic stage,visible,some die during pupal stage" "macrochaeta,intersegmental nerve,anterior fascicle & synapse,embryonic/larval brain,mesothoracic tergum,trichogen cell" FBgn0005154 l(2)G97 lethal (2) G97 http://flybase.org/reports/FBgn0005154 - gene - - - l(2)G97 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0084016 CG41453 - http://flybase.org/reports/FBgn0084016 protein_coding_gene - - - CG41453 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030946 CG6659 - http://flybase.org/reports/FBgn0030946 protein_coding_gene mannosyltransferase activity ; GO:0000030 | inferred from biological aspect of ancestor with PANTHER:PTN001266774 protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan ; GO:0018406 | inferred from biological aspect of ancestor with PANTHER:PTN001266774 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR018732 nuclear inner membrane ; GO:0005637 | inferred from biological aspect of ancestor with PANTHER:PTN001266774 CG6659 "IPR018732:Dpy-19/Dpy-19-like, IPR030038:C-mannosyltransferase Dpy-19" CG6659 27-Aug-18 DroID_v2018_08 "Drer\dpy19l1l, Drer\dpy19l3" - Cele\dpy-19 "Xtro\dpy19l4, Xtro\dpy19l1" "Mmus\Dpy19l3, Mmus\Dpy19l2, Mmus\Dpy19l4, Mmus\Dpy19l1" "Hsap\DPY19L3, Hsap\DPY19L2, Hsap\DPY19L4, Hsap\DPY19L1" "viable,fertile" FBgn0035763 CG8602 - http://flybase.org/reports/FBgn0035763 protein_coding_gene - transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011701 "anon-WO0118547.382, anon-WO0118547.349, CG8602" "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG8602 27-Aug-18 DroID_v2018_08 "Drer\mfsd1, Drer\im:7160594" - - "Xtro\mfsd1, Xtro\LOC100487982" Mmus\Mfsd1 Hsap\MFSD1 FBgn0016953 tilJ touch insensitive larva J http://flybase.org/reports/FBgn0016953 - gene - - - "line 366, tilJ" - - 27-Aug-18 DroID_v2018_08 - - - - - - "touch sensitivity defective,recessive,behavior defective,uncoordinated" FBgn0044455 EP3561 EP3561 http://flybase.org/reports/FBgn0044455 gene - - - EP3561 - - 27-Aug-18 DroID_v2018_08 - - - - - - neuroanatomy defective "intersegmental nerve,anterior fascicle & synapse | supernumerary" FBgn0037779 CG12811 - http://flybase.org/reports/FBgn0037779 protein_coding_gene - - - CG12811 IPR031993:Domain of unknown function DUF4789 CG12811 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033190 Gpo2 - http://flybase.org/reports/FBgn0033190 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 glycerol-3-phosphate dehydrogenase activity ; GO:0004368 | inferred from sequence or structural similarity with UniProtKB:P43304 "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000447, InterPro:IPR006076, InterPro:IPR023753 glycerol-3-phosphate metabolic process ; GO:0006072 | inferred from electronic annotation with InterPro:IPR000447 glycerol metabolic process ; GO:0006071 | inferred from sequence or structural similarity with UniProtKB:P43304" glycerol-3-phosphate dehydrogenase complex ; GO:0009331 | inferred from electronic annotation with InterPro:IPR000447 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:P43304 "146747_at, CG2137, alpha-GPO, Gpo, GPO, gpo-2, GPO-2" "IPR000447:FAD-dependent glycerol-3-phosphate dehydrogenase, IPR002048:EF-hand domain, IPR006076:FAD dependent oxidoreductase, IPR011992:EF-hand domain pair, IPR031656:Alpha-glycerophosphate oxidase, C-terminal, IPR023753:FAD/NAD(P)-binding domain" CG2137 27-Aug-18 DroID_v2018_08 Drer\gpd2 Scer\GUT2 "Cele\Y50E8A.6, Cele\T25G3.4" Xtro\gpd2 Mmus\Gpd2 Hsap\GPD2 viable FBgn0002558 lop lobula plateless http://flybase.org/reports/FBgn0002558 - gene - - - "N684, lop" - - 27-Aug-18 DroID_v2018_08 - - - - - - neuroanatomy defective lobula plate FBgn0011634 l(2)T57h7 lethal (2) T57h7 http://flybase.org/reports/FBgn0011634 FBgn0005177 gene - - - l(2)T57h7 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0259876 Cap-G Chromosome associated protein G http://flybase.org/reports/FBgn0259876 protein_coding_gene - neurogenesis ; GO:0022008 | inferred from mutant phenotype epithelium development ; GO:0060429 | inferred from mutant phenotype chromosome condensation ; GO:0030261 | inferred from mutant phenotype germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype mitotic chromosome condensation ; GO:0007076 | inferred from mutant phenotype mitotic sister chromatid segregation ; GO:0000070 | inferred from mutant phenotype mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype sister chromatid segregation ; GO:0000819 | inferred from mutant phenotype synaptonemal complex disassembly ; GO:0070194 | inferred from mutant phenotype "chromatin ; GO:0000785 | inferred from direct assay nuclear heterochromatin ; GO:0005720 | colocalizes_with inferred from direct assay chromosome, centromeric region ; GO:0000775 | colocalizes_with inferred from direct assay condensin complex ; GO:0000796 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay condensin complex ; GO:0000796 | inferred from sequence or structural similarity with HGNC:24304 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000373921" "CAP-G, Cap-G, CapG, l(2)49Ff, CG17054, CG30057, CG13327, dcap-g, cap-G, dCAP-G, DCAP-G, CG34438, vr9, vr-9, l(2)vr9, DmCAP-G, dCap-G, cap-g" "IPR016024:Armadillo-type fold, IPR027165:Condensin complex subunit 3, IPR011989:Armadillo-like helical, IPR025977:Nuclear condensin complex subunit 3, C-terminal domain" CG34438 27-Aug-18 DroID_v2018_08 Drer\ncapg Scer\YCG1 - Xtro\ncapg Mmus\Ncapg Hsap\NCAPG DRSC06653 IE 3.254948018 0.570605478 1.724249188 0.641673269 -0.18038739 1.071479412 FBgn0266418 wake wide awake http://flybase.org/reports/FBgn0266418 protein_coding_gene GABA receptor binding ; GO:0050811 | inferred from physical interaction with Rdl "signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR000159 regulation of establishment of bipolar cell polarity ; GO:0061172 | inferred from mutant phenotype asymmetric stem cell division ; GO:0098722 | inferred from mutant phenotype establishment of mitotic spindle orientation ; GO:0000132 | inferred from mutant phenotype positive regulation of circadian sleep/wake cycle, sleep ; GO:0045938 | inferred from mutant phenotype asymmetric neuroblast division ; GO:0055059 | inferred from mutant phenotype" spindle ; GO:0005819 | inferred from direct assay centrosome ; GO:0005813 | inferred from direct assay "ban, wake, CG42686, CG6954, CG45058, CG17622, CG17623" "IPR020683:Ankyrin repeat-containing domain, IPR002110:Ankyrin repeat, IPR013783:Immunoglobulin-like fold, IPR003961:Fibronectin type III, IPR000159:Ras-associating (RA) domain" CG45058 27-Aug-18 DroID_v2018_08 Drer\si:ch211-277e21.2 - Cele\R07E4.1 "Xtro\ankfn1, Xtro\LOC100490407" Mmus\Ankfn1 Hsap\ANKFN1 FBgn0266100 CG44837 - http://flybase.org/reports/FBgn0266100 protein_coding_gene dipeptidase activity ; GO:0016805 | inferred from biological aspect of ancestor with PANTHER:PTN000047764 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR008257 - "CG44837, CG14126, CG34420, CG5917, CG14129" "IPR008257:Renal dipeptidase family, IPR032466:Metal-dependent hydrolase" CG44837 27-Aug-18 DroID_v2018_08 "Drer\dpep1, Drer\dpep2" - - "Xtro\dpep1, Xtro\dpep2" "Mmus\Dpep2, Mmus\Dpep1, Mmus\Dpep3" "Hsap\DPEP2, Hsap\DPEP1, Hsap\DPEP3" DRSC10133 I -0.636539603 -1.534662136 0.855732895 -1.464536939 0.727738114 -0.04722746 FBgn0263401 CG43447 - http://flybase.org/reports/FBgn0263401 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43447, lincRNA.869" - CG43447 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034838 CG12782 - http://flybase.org/reports/FBgn0034838 protein_coding_gene - - - CG12782 "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR019775:WD40 repeat, conserved site" CG12782 27-Aug-18 DroID_v2018_08 Drer\rae1 "Scer\GLE2, Scer\BUB3" Cele\rae-1 Xtro\rae1 Mmus\Rae1 Hsap\RAE1 viable FBgn0022810 E(faf)bE160 Enhancer of faf bE160 http://flybase.org/reports/FBgn0022810 - gene - - - E(faf)bE160 - - 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0264445 lncRNA:CR43863 - http://flybase.org/reports/FBgn0264445 non_protein_coding_gene - - - CR43863 - CR43863 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036993 CG5910 - http://flybase.org/reports/FBgn0036993 protein_coding_gene - - - "CK02563, CG5910" - CG5910 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" FBgn0035121 Tudor-SN Tudor staphylococcal nuclease http://flybase.org/reports/FBgn0035121 protein_coding_gene nuclease activity ; GO:0004518 | inferred from direct assay gene silencing by RNA ; GO:0031047 | inferred from electronic annotation with InterPro:IPR016685 spermatogenesis ; GO:0007283 | inferred from mutant phenotype RNA catabolic process ; GO:0006401 | inferred from biological aspect of ancestor with PANTHER:PTN000266556 negative regulation of transposition ; GO:0010529 | inferred from genetic interaction with piwi nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay lipid particle ; GO:0005811 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay RISC complex ; GO:0016442 | inferred from direct assay "TSN, TSN-1, CG7008, Tudor-SN, tudor-SN, TUDOR-SN, p100, SND1, dP100" "IPR002999:Tudor domain, IPR016071:Staphylococcal nuclease (SNase-like), OB-fold, IPR016685:RNA-induced silencing complex, nuclease component Tudor-SN" CG7008 27-Aug-18 DroID_v2018_08 "Drer\si:dkeyp-93d12.1, Drer\tdrd7a, Drer\stk31, Drer\snd1" Scer\LCL3 Cele\tsn-1 Xtro\snd1 "Mmus\Stk31, Mmus\Snd1, Mmus\Tdrd6" "Hsap\TDRD6, Hsap\SND1, Hsap\TDRD15, Hsap\STK31, Hsap\TDRD5" "viable,fertile" FBgn0037566 mRpL1 mitochondrial ribosomal protein L1 http://flybase.org/reports/FBgn0037566 protein_coding_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with EMBL:AB049632 box H/ACA snoRNA binding ; GO:0034513 | inferred from biological aspect of ancestor with PANTHER:PTN000560394 structural constituent of ribosome ; GO:0003735 | traceable author statement snRNA pseudouridine synthesis ; GO:0031120 | inferred from biological aspect of ancestor with PANTHER:PTN000560394 rRNA pseudouridine synthesis ; GO:0031118 | inferred from biological aspect of ancestor with PANTHER:PTN000560394 mitochondrial translation ; GO:0032543 | traceable author statement maturation of LSU-rRNA ; GO:0000470 | inferred from biological aspect of ancestor with PANTHER:PTN000559990 translation ; GO:0006412 | inferred from sequence or structural similarity with EMBL:AB049632 cleavage involved in rRNA processing ; GO:0000469 | inferred from biological aspect of ancestor with PANTHER:PTN000560394 box H/ACA snoRNP complex ; GO:0031429 | inferred from biological aspect of ancestor with PANTHER:PTN000560394 mitochondrial large ribosomal subunit ; GO:0005762 | traceable author statement mitochondrial large ribosomal subunit ; GO:0005762 | inferred from sequence or structural similarity with EMBL:AB049632 "L1, CG7494, mRpL1" "IPR005879:Ribosomal protein L1, mitochondrial, IPR016095:Ribosomal protein L1, 3-layer alpha/beta-sandwich, IPR028364:Ribosomal protein L1/ribosomal biogenesis protein, IPR023674:Ribosomal protein L1-like" CG7494 27-Aug-18 DroID_v2018_08 Drer\mrpl1 "Scer\NHP2, Scer\PLM2, Scer\MRPL1" Cele\mrpl-1 Xtro\mrpl1 Mmus\Mrpl1 Hsap\MRPL1 "viable,fertile,visible" trichogen cell DRSC16251 I -1.85613842 -0.653112708 -0.926021638 -0.212620155 0.304789144 1.146192678 FBgn0069971 CG40496 - http://flybase.org/reports/FBgn0069971 protein_coding_gene - - - CG40496 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0024358 ES2-1 Enhancer of GMR-sina 2-1 http://flybase.org/reports/FBgn0024358 - gene - - - ES2-1 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036732 Oatp74D Organic anion transporting polypeptide 74D http://flybase.org/reports/FBgn0036732 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from sequence or structural similarity with Oatp58Db active transmembrane transporter activity ; GO:0022804 | inferred from sequence or structural similarity with Oatp58Db organic substance transport ; GO:0071702 | inferred from sequence or structural similarity with Oatp58Db integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity with Oatp58Db intracellular organelle ; GO:0043229 | inferred from direct assay "CG7571, oatp 74D, Oatp74D" "IPR020846:Major facilitator superfamily domain, IPR004156:Organic anion transporter polypeptide OATP, IPR002350:Kazal domain" CG7571 27-Aug-18 DroID_v2018_08 "Drer\slco5a1, Drer\slco1f1, Drer\slco2b1, Drer\slco4a1, Drer\LOC570448, Drer\LOC101883455, Drer\slco1d1, Drer\LOC100334356, Drer\slco1f4, Drer\slco1c1, Drer\slco1f3, Drer\slco3a1, Drer\LOC100536648, Drer\slco1f2, Drer\slco2a1" - "Cele\Y32F6B.1, Cele\F21G4.1, Cele\F47E1.2, Cele\F47E1.4" "Xtro\slco1b3, Xtro\slco3a1, Xtro\slco4c1, Xtro\slco5a1, Xtro\slco2a1, Xtro\slco4a1" "Mmus\Slco2a1, Mmus\Slco1a5, Mmus\Slco2b1, Mmus\Slco4c1, Mmus\Slco1a1, Mmus\Slco1a6, Mmus\Slco1a4, Mmus\Slco4a1, Mmus\Gm5724, Mmus\Slco6d1, Mmus\Slco3a1, Mmus\Slco1b2, Mmus\Slco1c1, Mmus\Gm6614, Mmus\Slco5a1, Mmus\Slco6c1" "Hsap\SLCO5A1, Hsap\SLCO1B7, Hsap\SLCO1B3, Hsap\SLCO2A1, Hsap\SLCO6A1, Hsap\SLCO3A1, Hsap\SLCO1B1, Hsap\SLCO1A2, Hsap\SLCO1C1, Hsap\SLCO2B1, Hsap\SLCO4C1, Hsap\SLCO4A1" "viable,visible" mesothoracic tergum FBgn0011952 tRNA:Arg-TCG-2-1 transfer RNA:Arginine-TCG 2-1 http://flybase.org/reports/FBgn0011952 "FBgn0011947, FBgn0052624, FBgn0060083" tRNA_gene CGA codon-amino acid adaptor activity ; GO:0033431 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033431 cytosol ; GO:0005829 | inferred by curator from GO:0033431 "tRNA-Arg, tRNA[arg], AE002593.trna1-ArgTCG, tRNA:R1, tRNA:arg1, tRNA:R:TCG:AE002593-a, CR32624, tRNA:arg12Ee, chrX.trna5-ArgTCG, tRNA-Arg-TCG-2-1, tRNA:Arg-TCG-2-1, tRNA:R:12Ee, CGA" - CR32624 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037764 CG9459 - http://flybase.org/reports/FBgn0037764 protein_coding_gene fatty acid elongase activity ; GO:0009922 | inferred from sequence or structural similarity with bond fatty acid elongation ; GO:0030497 | inferred from sequence or structural similarity with bond integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002076 cellular_component ; GO:0005575 | no biological data available "CT26804, CG9459" "IPR002076:ELO family, IPR030457:ELO family, conserved site" CG9459 27-Aug-18 DroID_v2018_08 "Drer\elovl4a, Drer\elovl8b, Drer\elovl1a, Drer\elovl5, Drer\elovl7a, Drer\elovl4b, Drer\elovl8a, Drer\elovl2, Drer\elovl1b, Drer\elovl7b" "Scer\ELO2, Scer\ELO1, Scer\ELO3" Cele\elo-9 "Xtro\elovl2, Xtro\elovl1, Xtro\elovl7, Xtro\elovl5" "Mmus\Elovl3, Mmus\Elovl7, Mmus\Elovl5, Mmus\Elovl4, Mmus\Elovl2, Mmus\Elovl1" "Hsap\ELOVL4, Hsap\ELOVL3, Hsap\ELOVL1, Hsap\ELOVL5, Hsap\ELOVL2, Hsap\ELOVL7" viable FBgn0085569 CG41242 - http://flybase.org/reports/FBgn0085569 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG41242 - CG41242 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0052424 CG32424 - http://flybase.org/reports/FBgn0052424 protein_coding_gene - - - CG32424 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037313 CG1161 - http://flybase.org/reports/FBgn0037313 protein_coding_gene - - integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR008853 CG1161 IPR008853:TMEM9 CG1161 27-Aug-18 DroID_v2018_08 "Drer\tmem9, Drer\tmem9b" - Cele\R12C12.6 - "Mmus\Tmem9b, Mmus\Tmem9" "Hsap\TMEM9, Hsap\TMEM9B" lethal FBgn0011653 mas masquerade http://flybase.org/reports/FBgn0011653 - protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues peptidase activity ; GO:0008233 | NOT traceable author statement "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" plasma membrane ; GO:0005886 | inferred from direct assay "SPH79, c-SPH79, CG15002, mas" "IPR018114:Serine proteases, trypsin family, histidine active site, IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan" CG15002 27-Aug-18 DroID_v2018_08 - - Cele\svh-1 Xtro\cfi Mmus\Cfi "Hsap\CFI, Hsap\PLG, Hsap\PRSS21" " embryonic stage--pupal stage , embryonic stage | stage 12-17 , embryonic stage | stage 14-17 , embryonic stage | stage 11-13 " " epidermis

, tracheal system

, ventral midline | restricted

" " embryonic stage , embryonic stage | stage 14-17 " " tracheal system

, embryonic/larval tracheal system

, epidermis

" "smell perception defective,taste perception defective,lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of pupal stage,some die during pupal stage" "lateral transverse muscle,ventral acute muscle,ventral longitudinal muscle,lateral oblique muscle 1,longitudinal connective,commissure,aCC neuron,pCC neuron,peripheral nervous system" FBgn0039359 RpL27 Ribosomal protein L27 http://flybase.org/reports/FBgn0039359 protein_coding_gene "structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR001141, InterPro:IPR018262 structural constituent of ribosome ; GO:0003735 | traceable author statement" "translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR001141, InterPro:IPR018262 centrosome organization ; GO:0051297 | inferred from mutant phenotype cytoplasmic translation ; GO:0002181 | traceable author statement centrosome duplication ; GO:0051298 | inferred from mutant phenotype" "ribosome ; GO:0005840 | inferred from electronic annotation with InterPro:IPR001141, InterPro:IPR018262 cytosolic large ribosomal subunit ; GO:0022625 | traceable author statement" "CG4759, RpL27, RpL27e, RPL27, chr3R:21510055..21510241" "IPR018262:Ribosomal protein L27e, conserved site, IPR001141:Ribosomal protein L27e, IPR005824:KOW, IPR008991:Translation protein SH3-like domain, IPR014722:Ribosomal protein L2 domain 2" CG4759 27-Aug-18 DroID_v2018_08 Drer\rpl27 "Scer\RPL27A, Scer\RPL27B" Cele\rpl-27 Xtro\rpl27 "Mmus\LOC108167922, Mmus\Rpl27" Hsap\RPL27 lethal DRSC15638 EK -1.495305073 -0.258025489 0.356025419 -4.000192804 1.491885399 4.7943074 FBgn0002779 mo micro-oculus http://flybase.org/reports/FBgn0002779 - gene - - - mo - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile,visible,recessive" "eye,wing,wing hair" FBgn0003035 par paralog http://flybase.org/reports/FBgn0003035 - gene molecular_function ; GO:0003674 | no biological data available nuclear migration ; GO:0007097 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "fs(1)A1122[ts], fs(1)A1122, par" - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,maternal effect,recessive,heat sensitive" "ovary,maternal effect,heat sensitive,egg chamber,blastoderm embryo,pole cell,gonad,adult cuticle,wing vein,cleavage nucleus" FBgn0038922 Idh3b - http://flybase.org/reports/FBgn0038922 protein_coding_gene isocitrate dehydrogenase (NAD+) activity ; GO:0004449 | inferred from sequence or structural similarity with UniProtKB:O43837 tricarboxylic acid cycle ; GO:0006099 | inferred from sequence or structural similarity with UniProtKB:O43837 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:O43837 microtubule associated complex ; GO:0005875 | inferred from direct assay "FBgn0038922, CG6439, Idh" "IPR004434:Isocitrate dehydrogenase NAD-dependent, IPR024084:Isopropylmalate dehydrogenase-like domain" CG6439 27-Aug-18 DroID_v2018_08 "Drer\idh3b, Drer\idh3a, Drer\idh3g" Scer\IDH1 "Cele\idha-1, Cele\idhg-2, Cele\idhb-1, Cele\idhg-1" "Xtro\idh3g, Xtro\idh3a, Xtro\idh3b" "Mmus\Idh3g, Mmus\4933405O20Rik, Mmus\Idh3a, Mmus\Idh3b" "Hsap\IDH3A, Hsap\IDH3B, Hsap\IDH3G" "lethal,viable,fertile,partially lethal - majority die" FBgn0011166 l(1)DM-3 lethal (1) DM-3 http://flybase.org/reports/FBgn0011166 FBgn0010204 gene - - - l(1)DM-3 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0082688 E(ftz)1815 E(ftz)1815 http://flybase.org/reports/FBgn0082688 gene - - - "1815, E(ftz)1815" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001194 hir heterochromatic recombination inducer http://flybase.org/reports/FBgn0001194 - gene - - - hir - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259556 B2011 - http://flybase.org/reports/FBgn0259556 gene - - - B2011 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0000899 fs(1)M108 female sterile (1) M108 http://flybase.org/reports/FBgn0000899 - gene - - - fs(1)M108 - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive,lethal,maternal effect" FBgn0001235 hth homothorax http://flybase.org/reports/FBgn0001235 "FBgn0010875, FBgn0011583, FBgn0015762, FBgn0016022, FBgn0025968" protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P40427 transcription factor binding ; GO:0008134 | inferred from physical interaction with exd DNA binding ; GO:0003677 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with exd transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | contributes_to inferred from physical interaction with exd transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding ; GO:0003705 | inferred from direct assay transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from mutant phenotype enhancer binding ; GO:0035326 | inferred from physical interaction with dpp" "regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from mutant phenotype salivary gland boundary specification ; GO:0007432 | traceable author statement salivary gland boundary specification ; GO:0007432 | non-traceable author statement compound eye development ; GO:0048749 | inferred from genetic interaction with L peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype segmentation ; GO:0035282 | inferred from mutant phenotype somatic muscle development ; GO:0007525 | inferred from mutant phenotype specification of segmental identity, antennal segment ; GO:0007383 | inferred from mutant phenotype eye development ; GO:0001654 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype specification of segmental identity, head ; GO:0007380 | inferred from mutant phenotype peripheral nervous system development ; GO:0007422 | non-traceable author statement brain development ; GO:0007420 | inferred from mutant phenotype protein localization to nucleus ; GO:0034504 | inferred from physical interaction with exd head morphogenesis ; GO:0060323 | inferred from mutant phenotype leg disc proximal/distal pattern formation ; GO:0007479 | traceable author statement peripheral nervous system development ; GO:0007422 | traceable author statement haltere morphogenesis ; GO:0048735 | inferred from mutant phenotype imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype regulation of cell fate specification ; GO:0042659 | inferred from mutant phenotype regulation of neuron differentiation ; GO:0045664 | inferred from mutant phenotype proximal/distal pattern formation ; GO:0009954 | traceable author statement Malpighian tubule development ; GO:0072002 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from direct assay compound eye photoreceptor fate commitment ; GO:0001752 | inferred from mutant phenotype protein import into nucleus, translocation ; GO:0000060 | inferred from mutant phenotype specification of animal organ identity ; GO:0010092 | traceable author statement positive regulation of decapentaplegic signaling pathway ; GO:0090098 | inferred from mutant phenotype" transcription factor complex ; GO:0005667 | inferred from physical interaction with abd-A inferred from physical interaction with exd nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay transcription factor complex ; GO:0005667 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay "MEIS1, Hth, Dm-HTH, P53, CG17117, dtl, hth2, hth1, 1422/04, 1323/07, anon-EST:Liang-2.13, clone 2.13, l(3)86Ca, l(3)05745, Meis1, hth, HTH, homothorax" "IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR008422:Homeobox KN domain, IPR032453:Homeobox protein PKNOX/Meis, N-terminal" CG17117 27-Aug-18 DroID_v2018_08 "Drer\irx2a, Drer\meis2b, Drer\pknox1.2, Drer\irx5b, Drer\meis1a, Drer\tgif1, Drer\meis2a, Drer\meis3, Drer\pknox1.1, Drer\irx7, Drer\irx6a, Drer\mkxa, Drer\irx3b, Drer\irx5a, Drer\irx4a, Drer\irx4b, Drer\irx1b, Drer\irx1a, Drer\irx3a, Drer\meis1b, Drer\pknox2" "Scer\TOS8, Scer\HMRA2, Scer\MATALPHA2, Scer\HMLALPHA2, Scer\CUP9" Cele\unc-62 "Xtro\meis1, Xtro\pknox2, Xtro\irx5, Xtro\meis3, Xtro\tgif2, Xtro\mkx, Xtro\meis2, Xtro\irx2, Xtro\irx4, Xtro\irx3, Xtro\irx1, Xtro\tgif1" "Mmus\Pknox2, Mmus\Irx3, Mmus\Meis1, Mmus\Irx4, Mmus\Mkx, Mmus\Meis3, Mmus\Tgif2lx2, Mmus\Tgif1, Mmus\Meis2, Mmus\Tgif2lx1, Mmus\Pknox1, Mmus\Tgif2, Mmus\Irx1, Mmus\Irx5, Mmus\Irx6, Mmus\Irx2" "Hsap\IRX5, Hsap\TGIF2LY, Hsap\IRX1, Hsap\IRX4, Hsap\PKNOX1, Hsap\MEIS1, Hsap\MEIS2, Hsap\IRX3, Hsap\TGIF2LX, Hsap\TGIF2-C20orf24, Hsap\IRX6, Hsap\TGIF1, Hsap\TGIF2, Hsap\MEIS3, Hsap\MKX, Hsap\PKNOX2, Hsap\IRX2" " embryonic stage , larval stage | third instar , larval stage , embryonic stage | mid , embryonic stage | stage 7 , embryonic stage | stage >=15 , embryonic stage | stage >=11 , embryonic stage | stage >=6 , embryonic stage | stage >=13 , embryonic stage | cellular blastoderm , embryonic stage -- adult stage " " embryonic thorax

, embryonic nervous system

, antennal disc

, midgut constriction 1 | posterior to

, ventral thoracic disc

, endoderm | mid

, mesothoracic pleurum | presumptive

, Malpighian tubule

, organism | 10-90% egg length

, gastric caecum | primordium

, embryonic nervous system of thorax

, labral segment

, ectoderm

, peripodial epithelium

, embryonic central nervous system

, wing hinge | presumptive

, visceral mesoderm

, midgut constriction 3 | anterior to

, scutum | presumptive

, dorsal mesothoracic disc

, photoreceptor cell

, embryonic maxillary segment

, eye-antennal disc

, eye disc

, embryonic Malpighian tubule

, embryonic mandibular segment

, ptilinum | presumptive

, head capsule | presumptive

, ocellus | presumptive

" " larval stage | third instar , embryonic stage | stage >=13 , embryonic stage | stage >=11 , embryonic stage | stage >=15 , embryonic stage | stage >=6 , larval stage | second instar , embryonic stage " " ventral thoracic disc

, wing hinge | presumptive

, embryonic central nervous system

, labral segment

, embryonic nervous system of thorax

, dorsal mesothoracic disc

, ectoderm

, embryonic maxillary segment

, ocellus | presumptive

, embryonic Malpighian tubule

, peripodial epithelium

, ptilinum | presumptive

, mesothoracic pleurum | presumptive

, eye disc

, antennal disc

, visceral mesoderm

, embryonic mandibular segment

, head capsule | presumptive

, scutum | presumptive

, photoreceptor cell

, embryonic thorax

" "lethal,recessive,homeotic,partially lethal - majority die,some die during pharate adult stage,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage,neuroanatomy defective,viable,visible,somatic clone,cell autonomous,size defective,dominant,male,planar polarity defective,cell non-autonomous,heat sensitive" "lch5 neuron,leg,ectopic,antenna,peripheral nervous system,sense organ & neuron,cephalopharyngeal skeleton,embryonic head,embryonic segment,abdominal 1 lch5 neuron,abdominal 2 lch5 neuron,abdominal 3 lch5 neuron,abdominal 4 lch5 neuron,abdominal 5 lch5 neuron,abdominal 6 lch5 neuron,abdominal 7 lch5 neuron,abdominal lateral pentascolopidial chordotonal organ lch5,embryonic epidermis,somatic clone,metatarsus,tarsal segment 2,tarsal segment 3,tarsal segment 4,tarsal segment,pretarsus,mesothoracic tibial spur bristle,mesothoracic tibial apical bristle,prothoracic leg,mesothoracic leg,metathoracic leg,eye disc,embryonic/first instar larval cuticle,denticle belt,female genitalia,clasper,adult head,ventral,eye-antennal disc,antennal segment 2 & leg | somatic clone,antennal segment 3 & leg | somatic clone,eye & adult head | ventral,eye,photoreceptor cell,coxa,femur,tibia,motor neuron,glial cell,longitudinal connective,posterior commissure,embryonic ventral nervous system,cell autonomous,bract,wing margin,posterior,alula,wing sclerite,wing hinge,axillary cord,costal vein,wing vein L3,proximal,wing,double row,sensillum campaniformium of dorsal radius,wing margin bristle,scutellar bristle,wing disc,gena,rostral membrane,maxillary palpus,dorsal,embryonic thorax,abdominal segment 1,trochanter,dch3 neuron,embryonic/larval oenocyte precursor,medulla,transmedullary neuron Tm1,medullary intrinsic neuron Mi1,neuroblast NB6-4 of abdomen,neuroblast NB6-4 of thorax,flight muscle,extracoxal depressor muscle,embryonic brain & axon,adult abdominal segment 4,male,adult abdominal segment 5,ommatidium,eye photoreceptor cell,dorsal margin photoreceptor,somatic clone - Minute background,heat sensitive,second segment of antenna,third segment of antenna,presumptive embryonic/larval peripheral nervous system,embryonic/larval lymph gland,abdominal 1 lateral pentascolopidial chordotonal organ lch5,abdominal 2 lateral pentascolopidial chordotonal organ lch5,abdominal 3 lateral pentascolopidial chordotonal organ lch5,abdominal 4 lateral pentascolopidial chordotonal organ lch5,abdominal 5 lateral pentascolopidial chordotonal organ lch5,abdominal 6 lateral pentascolopidial chordotonal organ lch5,abdominal 7 lateral pentascolopidial chordotonal organ lch5,embryonic thorax & denticle | ectopic,photoreceptor cell & eye-antennal disc | ventral,prothoracic ventral denticle belt,mesothoracic ventral denticle belt,metathoracic ventral denticle belt,embryonic abdominal segment 1,prothoracic dorsal triscolopidial chordotonal organ dch3 & neuron,mesothoracic dorsal triscolopidial chordotonal organ dch3 & neuron,metathoracic dorsal triscolopidial chordotonal organ dch3 & neuron,distal,abdominal tergite 2,abdominal tergite 3,abdominal tergite & trichome | male | somatic clone,embryonic prothoracic segment,embryonic mesothoracic segment,embryonic metathoracic segment,pseudotrachea,arista,sex comb,abdominal tergite 5 & trichome | malepnr-MD237,abdominal tergite 6 & trichome | malepnr-MD237,tergite,dorsal margin photoreceptor cell R8,photoreceptor cell R8,dorsal margin photoreceptor cell R7,ventral thoracic disc,morphogenetic furrow,leg sensillum,leg & trichome | somatic clone,unguis,alula & wing sensillumBx-MS1096,scutum,medial,cell non-autonomous,dorsocentral bristle,microchaeta & scutumMS248,antennal disc,head capsule,abdominal tergite 5,abdominal tergite 6,head,wing blade,haltere,retina,photoreceptor cell R7,abdominal segment 2,abdominal segment,Keilin's organ" FBgn0027635 ms(1)266 ms(1)266 http://flybase.org/reports/FBgn0027635 - gene - - - ms(1)266 - - 27-Aug-18 DroID_v2018_08 - - - - - - male sterile spermatid & nucleus FBgn0030796 CG4829 - http://flybase.org/reports/FBgn0030796 protein_coding_gene glutathione hydrolase activity ; GO:0036374 | inferred from electronic annotation with InterPro:IPR000101 glutathione catabolic process ; GO:0006751 | inferred from electronic annotation with InterPro:IPR000101 neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype - CG4829 "IPR000101:Gamma-glutamyltranspeptidase, IPR029055:Nucleophile aminohydrolases, N-terminal" CG4829 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-222h21.12, Drer\si:ch73-59p9.2, Drer\ggt1l2.2, Drer\ggt5a, Drer\ggt5b, Drer\si:ch73-236c18.3, Drer\ggt1a, Drer\ggt1b" Scer\ECM38 "Cele\Y7A9A.1, Cele\Y97E10AR.2, Cele\H14N18.4, Cele\C53D5.5, Cele\T03D8.6, Cele\T19H12.6" "Xtro\ggt7, Xtro\ggt1, Xtro\ggt5" "Mmus\Ggt7, Mmus\Ggt1, Mmus\Ggt5, Mmus\Ggt6" "Hsap\GGT7, Hsap\GGT2, Hsap\GGT5, Hsap\GGTLC1, Hsap\GGTLC2, Hsap\GGT1, Hsap\GGT6" FBgn0086034 snoRNA:Me28S-G2743 - http://flybase.org/reports/FBgn0086034 snoRNA_gene - - - "snoRNA:Me28S-G2743, Me28S-Gm2743, CR34663" - CR34663 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0028150 l(3)S044601 lethal (3) S044601 http://flybase.org/reports/FBgn0028150 gene - - - "0446/01, l(3)S044601" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0004083 Y-seqs Y-chromosome sequences http://flybase.org/reports/FBgn0004083 FBgn0013400 repeat_region - - - "Y95-2, anon-Y95-2, Y-seqs" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037848 Tsp86D Tetraspanin 86D http://flybase.org/reports/FBgn0037848 protein_coding_gene molecular_function ; GO:0003674 | no biological data available border follicle cell migration ; GO:0007298 | inferred from mutant phenotype positive regulation of Notch signaling pathway ; GO:0045747 | inferred from mutant phenotype nervous system development ; GO:0007399 | inferred from mutant phenotype cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "CG4591, Dm.Tsp86D, Tsp86D" "IPR018499:Tetraspanin/Peripherin, IPR018503:Tetraspanin, conserved site, IPR000301:Tetraspanin, IPR008952:Tetraspanin, EC2 domain" CG4591 27-Aug-18 DroID_v2018_08 "Drer\tspan5a, Drer\tspan33a, Drer\rom1b, Drer\prph2b, Drer\zgc:113223, Drer\LOC799194, Drer\zmp:0000000545, Drer\zgc:110329, Drer\tspan5b, Drer\prph2a, Drer\rom1a, Drer\tspan14, Drer\tspan15, Drer\prph2l, Drer\tspan33b" - "Cele\tsp-12, Cele\tsp-20" "Xtro\prph2, Xtro\LOC100489375, Xtro\tspan5, Xtro\tspan33, Xtro\tspan14, Xtro\tspan17, Xtro\tspan15" "Mmus\Tspan14, Mmus\Tspan5, Mmus\Prph2, Mmus\Tspan15, Mmus\Rom1, Mmus\Tspan17, Mmus\Tspan10, Mmus\Tspan33" "Hsap\TSPAN33, Hsap\TSPAN14, Hsap\PRPH2, Hsap\TSPAN5, Hsap\TSPAN10, Hsap\ROM1, Hsap\TSPAN15, Hsap\TSPAN17" viable "sensory mother cell,somatic clone,supernumerary" FBgn0037068 Cpr78Cb Cuticular protein 78Cb http://flybase.org/reports/FBgn0037068 protein_coding_gene structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "anon-EST:ParkEST240, BcDNA:RE38359, Cpr78Cb, CG7663, DmelCpr78Cb" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG7663 27-Aug-18 DroID_v2018_08 Drer\LOC100003040 - "Cele\math-34, Cele\sdz-30, Cele\F44F1.4" - "Mmus\H2-K1, Mmus\2410137M14Rik" - viable FBgn0026357 Su(SuRaf1)10 Su(SuRaf1)10 http://flybase.org/reports/FBgn0026357 - gene - - - "Su[Su(Raf)1]10, Su(SuRaf1)10" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0021805 l(2)k16801 lethal (2) k16801 http://flybase.org/reports/FBgn0021805 - gene - - - l(2)k16801 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0250733 l(3)S006313 lethal (3) S006313 http://flybase.org/reports/FBgn0250733 gene - - - "l(3)S006313, l(3)s006313" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0266459 CG45084 - http://flybase.org/reports/FBgn0266459 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG45084, Dromel_CG4824_FBtr0080804_bicc_uORF" - CG45084 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0023465 anon-56Cc anon-56Cc http://flybase.org/reports/FBgn0023465 - gene - - - anon-56Cc - - 27-Aug-18 DroID_v2018_08 - - - - - - adult stage && oogenesis stage " ovary

, nurse cell

" FBgn0051493 CG31493 - http://flybase.org/reports/FBgn0051493 protein_coding_gene N-acetyltransferase activity ; GO:0008080 | inferred from biological aspect of ancestor with PANTHER:PTN001463139 nitrogen compound metabolic process ; GO:0006807 | inferred from biological aspect of ancestor with PANTHER:PTN001463139 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001463139 "CG2640, CG31493" IPR016181:Acyl-CoA N-acyltransferase CG31493 27-Aug-18 DroID_v2018_08 - - "Cele\anat-1, Cele\T10B5.4" - - - viable FBgn0085308 CG34279 - http://flybase.org/reports/FBgn0085308 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34279 IPR002350:Kazal domain CG34279 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0086909 CG31751 - http://flybase.org/reports/FBgn0086909 protein_coding_gene - - - "ct, CG15164, CG15163, CG31751, anon-ct" "IPR002575:Aminoglycoside phosphotransferase, IPR011009:Protein kinase-like domain" CG31751 27-Aug-18 DroID_v2018_08 "Drer\hykk.2, Drer\hykk.1" - - Xtro\hykk Mmus\Hykk Hsap\HYKK embryonic stage -- adult stage FBgn0265755 lncRNA:CR44562 - http://flybase.org/reports/FBgn0265755 non_protein_coding_gene - - - CR44562 - CR44562 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0026438 Eaat2 Excitatory amino acid transporter 2 http://flybase.org/reports/FBgn0026438 - protein_coding_gene glutamate:sodium symporter activity ; GO:0015501 | inferred from sequence or structural similarity taurine:sodium symporter activity ; GO:0005369 | inferred from direct assay L-aspartate transmembrane transporter activity ; GO:0015183 | inferred from direct assay taurine transport ; GO:0015734 | inferred from direct assay taurine transport ; GO:0015734 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR001991 plasma membrane ; GO:0005886 | inferred from sequence or structural similarity "dEAAT2, EAAT, CG3159, Eaat2, dEaat2" "IPR018107:Sodium:dicarboxylate symporter, conserved site, IPR001991:Sodium:dicarboxylate symporter" CG3159 27-Aug-18 DroID_v2018_08 "Drer\slc1a9, Drer\slc1a7b, Drer\slc1a3b, Drer\slc1a2b, Drer\slc1a7a, Drer\slc1a8a, Drer\slc1a4, Drer\slc1a5, Drer\slc1a6, Drer\slc1a1, Drer\slc1a2a, Drer\slc1a8b, Drer\slc1a3a" - "Cele\glt-1, Cele\glt-7, Cele\glt-4, Cele\glt-6, Cele\glt-3, Cele\glt-5" "Xtro\slc1a3, Xtro\slc1a1, Xtro\slc1a7, Xtro\slc1a4, Xtro\LOC100496635, Xtro\slc1a5, Xtro\slc1a2, Xtro\slc1a6" "Mmus\Slc1a3, Mmus\Slc1a7, Mmus\Slc1a5, Mmus\Slc1a2, Mmus\Slc1a6, Mmus\Slc1a4, Mmus\Slc1a1" "Hsap\SLC1A1, Hsap\SLC1A5, Hsap\SLC1A6, Hsap\SLC1A7, Hsap\SLC1A4, Hsap\SLC1A3, Hsap\SLC1A2" " embryonic stage | stage 15-16 , embryonic stage | stage 17 , adult stage , embryonic stage | stage 16-17 , larval stage | third instar " " Bolwig's organ | presumptive

, interneuron

, midline glial cell

, ocellus

, sense organ & neuron | subset

, larval central nervous system

, adult head

, retina

, ventral nerve cord

,

anterior , glial cell

, CNS glial cell | subset

" "viable,chemosensitive behavior defective" FBgn0259222 CG42322 - http://flybase.org/reports/FBgn0259222 protein_coding_gene - - - "CG42322, CG15690, CG15689, CG15688, CG31203" IPR026505:Solute carrier family 35 member F3/F4 CG42322 27-Aug-18 DroID_v2018_08 "Drer\slc35f3b, Drer\slc35f3a, Drer\slc35f4" - Cele\Y73B6BL.31 "Xtro\slc35f4, Xtro\slc35f3" "Mmus\Slc35f4, Mmus\Slc35f3" "Hsap\SLC35F3, Hsap\SLC35F4" FBgn0031751 CG9016 - http://flybase.org/reports/FBgn0031751 protein_coding_gene - - - "bs24f02.y1, bs20d08.y1, bs36f07.y1, bs29f11.y1, bs29e04.y1, bs28b03.y1, bs27b06.y1, bs25d03.y1, bs22a02.y1, bs21a02.y1, bs19d06.y1, bs18b05.y1, bs16d01.y1, bs16c10.y1, bs14b11.y1, bs13h06.y1, bs10f09.y1, bs10d11.y1, bs09c06.y1, bs07e11.y1, bs05g03.y1, bs03c03.y1, NEST:bs24f02, NEST:bs20d08, BcDNA:AT19175, NEST:bs09a09, NEST:bs36a03, CG9016" - CG9016 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" FBgn0003935 snRNA:U5:34A small nuclear RNA U5 at 34AB http://flybase.org/reports/FBgn0003935 "FBgn0003932, FBgn0051853" snRNA_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity" U5 snRNP ; GO:0005682 | inferred from sequence or structural similarity "U5, U5-34A, snRNA[[3]], K2, dU5, snRNA:U5:34AB, snRNA:U5, snRNA4, snRNA3, U5snRNA34AB, CR31853, U5snRNA, snRNA:U5:34A, U5:34A, U5 snRNA, U5 snRNA 34A, 34B U5" - CR31853 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0004686 mei-I1 meiotic I1 http://flybase.org/reports/FBgn0004686 - gene - - - mei-I1 - - 27-Aug-18 DroID_v2018_08 - - - - - - "meiotic cell cycle defective,male,recessive" "meiosis I,spermatocyte,spermatid" FBgn0016782 anon-8Db anon-8Db http://flybase.org/reports/FBgn0016782 - gene - - - anon-8Db - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030124 CG12667 - http://flybase.org/reports/FBgn0030124 protein_coding_gene - - - CG12667 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263572 mir-4981 mir-4981 stem loop http://flybase.org/reports/FBgn0263572 miRNA_gene - - - "mir-4981, dme-mir-4981, CR43557" - CR43557 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0023446 dre dark red http://flybase.org/reports/FBgn0023446 - gene - - - "dr, dre" - - 27-Aug-18 DroID_v2018_08 - - - - - - visible pigment cell FBgn0001676 l(1)EN13 lethal (1) from Eugene Nonautonomous 13 http://flybase.org/reports/FBgn0001676 - gene - - - l(1)EN13 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0030806 CG13001 - http://flybase.org/reports/FBgn0030806 protein_coding_gene molecular_function ; GO:0003674 | no biological data available nervous system development ; GO:0007399 | inferred from sequence or structural similarity with HGNC:24931 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:24931 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:24931 CG13001 "IPR018482:Zinc finger, C4H2-type" CG13001 27-Aug-18 DroID_v2018_08 Drer\zc4h2 - "Cele\ZK930.2, Cele\vab-23" Xtro\zc4h2 Mmus\Zc4h2 Hsap\ZC4H2 viable FBgn0065595 l(2)SH0892 lethal (2) SH0892 http://flybase.org/reports/FBgn0065595 gene - - - "l(2)SH0892, l(2)SH2 0892" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0065815 l(2)SH0379 lethal (2) SH0379 http://flybase.org/reports/FBgn0065815 gene - - - l(2)SH0379 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0260777 CG42571 - http://flybase.org/reports/FBgn0260777 protein_coding_gene - - - "CG42571, chr3L.16.093a" - CG42571 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0013587 l(3)97Db lethal (3) 97Db http://flybase.org/reports/FBgn0013587 - gene - - - "l(3)155, l(3)97Db" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0045863 blood\sORF blood element sORF http://flybase.org/reports/FBgn0045863 transposable_element_gene - - - blood\sORF - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0029118 ScsbetaG Sucb http://flybase.org/reports/FBgn0029118 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR013815, InterPro:IPR013816 succinate-CoA ligase (GDP-forming) activity ; GO:0004776 | inferred from sequence or structural similarity with UniProtKB:Q96I99" succinyl-CoA metabolic process ; GO:0006104 | inferred from electronic annotation with InterPro:IPR034722 tricarboxylic acid cycle ; GO:0006099 | inferred from sequence or structural similarity with UniProtKB:Q96I99 adult chitin-containing cuticle pigmentation ; GO:0048085 | inferred from mutant phenotype succinate-CoA ligase complex (GDP-forming) ; GO:0045244 | inferred from sequence or structural similarity with UniProtKB:Q96I99 lipid particle ; GO:0005811 | inferred from direct assay "142911_at, sucB, sucb, CG10622, Sucb, G-Sbeta" "IPR005809:Succinate--CoA synthetase, beta subunit, IPR005811:ATP-citrate lyase/succinyl-CoA ligase, IPR013650:ATP-grasp fold, succinyl-CoA synthetase-type, IPR013815:ATP-grasp fold, subdomain 1, IPR016102:Succinyl-CoA synthetase-like, IPR017866:Succinyl-CoA synthetase, beta subunit, conserved site, IPR034722:Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial" CG10622 27-Aug-18 DroID_v2018_08 "Drer\suclg2, Drer\sucla2" Scer\LSC2 "Cele\suca-1, Cele\sucg-1" "Xtro\suclg2, Xtro\sucla2" "Mmus\Sucla2, Mmus\Suclg2" "Hsap\SUCLG2, Hsap\SUCLA2" viable DRSC11294 K 1.405500056 0.080852975 0.703715679 -0.10521442 -0.050090907 1.520624111 FBgn0030930 Pgant7 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 http://flybase.org/reports/FBgn0030930 protein_coding_gene polypeptide N-acetylgalactosaminyltransferase activity ; GO:0004653 | inferred from direct assay oligosaccharide biosynthetic process ; GO:0009312 | inferred from direct assay Golgi stack ; GO:0005795 | non-traceable author statement endomembrane system ; GO:0012505 | inferred from direct assay "pgant7, CG6394, dGalNAc-T2, anon-WO02059370.15, GalNAc-T2, PGANT7" "IPR000772:Ricin B, lectin domain, IPR001173:Glycosyltransferase 2-like, IPR029044:Nucleotide-diphospho-sugar transferases" CG6394 27-Aug-18 DroID_v2018_08 "Drer\galnt16, Drer\galnt11, Drer\galnt3, Drer\galnt10, Drer\LOC103910015, Drer\wbscr17, Drer\LOC100535692, Drer\LOC100334784, Drer\galnt7, Drer\si:ch211-15e22.3, Drer\galnt2, Drer\galnt8a.1, Drer\LOC101882942, Drer\galnt9, Drer\galnt1, Drer\LOC568645, Drer\galnt6, Drer\galnt13, Drer\galnt18b, Drer\galnt14, Drer\galnt8b, Drer\LOC101886587, Drer\poc1bl, Drer\galnt12" - "Cele\gly-7, Cele\gly-11, Cele\gly-9, Cele\gly-3, Cele\gly-10" "Xtro\galnt6.1, Xtro\galnt7, Xtro\galnt15, Xtro\galnt16, Xtro\wbscr17, Xtro\galnt13, Xtro\galnt4, Xtro\galnt10, Xtro\galnt14, Xtro\galnt2, Xtro\galnt9, Xtro\galnt12, Xtro\galnt1" "Mmus\Galnt3, Mmus\Galnt18, Mmus\Galntl6, Mmus\Galnt1, Mmus\Galnt7, Mmus\Galnt12, Mmus\Galnt9, Mmus\Galnt13, Mmus\Galntl5, Mmus\Galnt2, Mmus\Galnt15, Mmus\Galnt16, Mmus\Galnt14, Mmus\Galnt11, Mmus\Galnt5, Mmus\Galnt4, Mmus\Galnt6, Mmus\Wbscr17, Mmus\Galnt10" "Hsap\GALNT15, Hsap\WBSCR17, Hsap\GALNT3, Hsap\GALNT18, Hsap\GALNT6, Hsap\GALNT4, Hsap\GALNT16, Hsap\GALNT5, Hsap\GALNT10, Hsap\GALNT13, Hsap\GALNTL5, Hsap\GALNT2, Hsap\GALNT8, Hsap\GALNT7, Hsap\GALNT1, Hsap\GALNT12, Hsap\GALNTL6, Hsap\POC1B-GALNT4, Hsap\GALNT11, Hsap\GALNT9, Hsap\GALNT14" "viable,fertile,lethal,partially lethal - majority die" FBgn0262899 CG43254 - http://flybase.org/reports/FBgn0262899 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43254, lincRNA.715" - CG43254 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000026 acj2 abnormal chemosensory jump 2 http://flybase.org/reports/FBgn0000026 - gene molecular_function ; GO:0003674 | no biological data available chemosensory jump behavior ; GO:0007636 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available acj2 - - 27-Aug-18 DroID_v2018_08 - - - - - - "chemosensitive behavior defective,recessive" FBgn0040513 kappaB-Ras kappaB-Ras http://flybase.org/reports/FBgn0040513 protein_coding_gene "GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR001806 GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR020849 GTP binding ; GO:0005525 | inferred from sequence model protein binding ; GO:0005515 | inferred from physical interaction with cact GTPase activity ; GO:0003924 | NOT inferred from sequence model" signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR020849 negative regulation of I-kappaB kinase/NF-kappaB signaling ; GO:0043124 | inferred from sequence or structural similarity membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR020849 "dkappaB-Ras, kappaB-Ras, CG1669, BcDNA:RH38596, B7YZS7, Q9V4L4-1" "IPR001806:Small GTPase superfamily, IPR020849:Small GTPase superfamily, Ras type, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG1669 27-Aug-18 DroID_v2018_08 "Drer\LOC100332969, Drer\rap2ab, Drer\rap2b, Drer\nkiras1, Drer\nkiras2, Drer\rap2c" - "Cele\rap-2, Cele\ZK669.5, Cele\kbrl-1, Cele\D1081.4, Cele\rap-3, Cele\Y52B11A.4" "Xtro\nkiras2, Xtro\nkiras1" "Mmus\Rap2b, Mmus\Nkiras2, Mmus\Gm266, Mmus\Nkiras1, Mmus\Rap2a, Mmus\Rap2c" "Hsap\RAP2C, Hsap\NKIRAS2, Hsap\RAP2A, Hsap\RAP2B, Hsap\NKIRAS1" FBgn0260755 CG42553 - http://flybase.org/reports/FBgn0260755 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG13886, CT33419, CG42553" IPR010733:Protein of unknown function DUF1308 CG42553 27-Aug-18 DroID_v2018_08 Drer\zgc:55781 - Cele\F33G12.3 Xtro\c7orf25 Mmus\AW209491 Hsap\C7orf25 FBgn0003590 Su(var)2-3 Suppressor of variegation 2-3 http://flybase.org/reports/FBgn0003590 - gene - - - "Su-var(2)3, Su(var)2-3" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,suppressor of variegation,dominant" FBgn0023436 ifa irregular facet http://flybase.org/reports/FBgn0023436 - gene - - - ifa - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "pigment cell,ommatidium" FBgn0037636 CG9821 - http://flybase.org/reports/FBgn0037636 protein_coding_gene - - nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001034975 "CG31442, anon-WO0118547.424, anon-WO0118547.399, CG9821, Ov29" IPR026780:Proline-rich nuclear receptor coactivator 1/2 CG9821 27-Aug-18 DroID_v2018_08 "Drer\pnrc1, Drer\pnrc2" - - - "Mmus\Pnrc2, Mmus\Pnrc1" "Hsap\PNRC1, Hsap\PNRC2" "lethal,viable,fertile,neuroanatomy defective" "presumptive embryonic/larval peripheral nervous system,ventral nerve cord commissure" DRSC16570 EK -0.611206603 0.813672327 -0.525268671 -3.069052823 2.284551098 1.981705373 FBgn0262099 CG42852 - http://flybase.org/reports/FBgn0262099 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42852, lincRNA.585" - CG42852 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085256 CG34227 - http://flybase.org/reports/FBgn0085256 protein_coding_gene - - extracellular space ; GO:0005615 | inferred from direct assay "CG34227, CG7738" - CG34227 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0266683 lncRNA:CR45173 - http://flybase.org/reports/FBgn0266683 non_protein_coding_gene - - - CR45173 - CR45173 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0025684 MFS18 Major Facilitator Superfamily Transporter 18 http://flybase.org/reports/FBgn0025684 FBgn0031605 protein_coding_gene transmembrane transporter activity ; GO:0022857 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 anion transport ; GO:0006820 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000184222 "CK02623, BEST:CK02623, CG15438, MFS18" "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG15438 27-Aug-18 DroID_v2018_08 "Drer\slc17a9a, Drer\slc17a9b" "Scer\THI73, Scer\YIL166C, Scer\TNA1, Scer\DAL5" "Cele\cima-1, Cele\slc-17.9, Cele\vnut-1" Xtro\slc17a9 Mmus\Slc17a9 Hsap\SLC17A9 viable FBgn0030314 CG11696 - http://flybase.org/reports/FBgn0030314 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 "b, CG11696" "IPR012934:Zinc finger, AD-type, IPR013087:Zinc finger C2H2-type" CG11696 27-Aug-18 DroID_v2018_08 "Drer\znf865, Drer\zgc:153116, Drer\prdm5" - "Cele\klf-3, Cele\klu-1, Cele\Y55F3AM.14" - "Mmus\Zfp212, Mmus\Zfp865, Mmus\Zfp667" "Hsap\ZNF805, Hsap\ZSCAN12, Hsap\ZNF865, Hsap\ZNF667, Hsap\ZNF783, Hsap\ZNF254, Hsap\ZNF671, Hsap\ZNF662, Hsap\PRDM5, Hsap\ZNF212, Hsap\ZNF763" FBgn0085276 CG34247 - http://flybase.org/reports/FBgn0085276 protein_coding_gene - - - CG34247 - CG34247 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051720 mthl15 methuselah-like 15 http://flybase.org/reports/FBgn0051720 protein_coding_gene G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity with mth cell surface receptor signaling pathway ; GO:0007166 | inferred from electronic annotation with InterPro:IPR017981 response to stress ; GO:0006950 | inferred from electronic annotation with InterPro:IPR010596 G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with mth integral component of plasma membrane ; GO:0005887 | inferred from sequence or structural similarity with mth "CG31720, mthl15" "IPR017981:GPCR, family 2-like, IPR023311:Methuselah ectodomain, domain 2, IPR000832:GPCR, family 2, secretin-like, IPR010596:Methuselah, N-terminal domain" CG31720 27-Aug-18 DroID_v2018_08 Drer\adgrf11 - - Xtro\gpr157 Mmus\Adgrb2 - FBgn0038852 HHEX Hematopoietically expressed homeobox http://flybase.org/reports/FBgn0038852 protein_coding_gene "transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding ; GO:0001227 | inferred from biological aspect of ancestor with PANTHER:PTN001963821 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from sequence or structural similarity with MGI:MGI:96086 RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from biological aspect of ancestor with PANTHER:PTN001963821" regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity with MGI:MGI:96086 negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from biological aspect of ancestor with PANTHER:PTN001963821 response to sucrose ; GO:0009744 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype glucose metabolic process ; GO:0006006 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from sequence or structural similarity with MGI:MGI:96086 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN001963821 "CG7056, HHEX, dHHEX" "IPR001356:Homeobox domain, IPR009057:Homeobox domain-like, IPR017970:Homeobox, conserved site, IPR020479:Homeobox domain, metazoa" CG7056 27-Aug-18 DroID_v2018_08 "Drer\hhex, Drer\hmx2, Drer\tlx2, Drer\tlx1, Drer\hmx3b, Drer\hmx4, Drer\LOC100008066, Drer\hmx1" - "Cele\ceh-93, Cele\pha-2, Cele\ceh-51, Cele\ttx-1, Cele\ceh-76, Cele\mls-2" "Xtro\nkx3-1, Xtro\tlx3, Xtro\tlx1, Xtro\tlx2, Xtro\hmx3, Xtro\hmx1, Xtro\hmx2, Xtro\hhex" "Mmus\Tlx2, Mmus\Hmx3, Mmus\Hhex, Mmus\Hmx2, Mmus\Hmx1, Mmus\Nkx2-9, Mmus\Nkx3-1, Mmus\Dbx2, Mmus\Tlx3, Mmus\Tlx1" "Hsap\HHEX, Hsap\HMX3, Hsap\NKX3-1, Hsap\HMX2, Hsap\TLX2, Hsap\TLX1, Hsap\TLX3, Hsap\DBX2, Hsap\ALX3" "lethal,chemical conditional,neuroanatomy defective,visible,partially lethal - majority die,some die during pupal stage,chemical sensitive,male limited,small body,female limited,viable,fertile" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" DRSC16186 E 1.06117676 -0.050501548 3.497706995 -1.716624444 -1.272295111 -0.103251705 FBgn0039470 CG6296 - http://flybase.org/reports/FBgn0039470 protein_coding_gene phosphatidylcholine 1-acylhydrolase activity ; GO:0008970 | inferred from electronic annotation with InterPro:IPR002334 lipase activity ; GO:0016298 | inferred from sequence or structural similarity with MGI:MGI:96820 lipid catabolic process ; GO:0016042 | inferred from sequence or structural similarity with MGI:MGI:96820 cellular_component ; GO:0005575 | no biological data available "CG6296, DmelL7" "IPR000734:Triacylglycerol lipase family, IPR002334:Vespid venom allergen phospholipase A1, IPR013818:Lipase/vitellogenin, IPR033906:Lipase, N-terminal, IPR029058:Alpha/Beta hydrolase fold" CG6296 27-Aug-18 DroID_v2018_08 "Drer\lipca, Drer\lpl, Drer\LOC101884800, Drer\lipib, Drer\LOC100331214, Drer\pla1a, Drer\lipg, Drer\lipia" - - "Xtro\lipg, Xtro\lpl" "Mmus\Lipi, Mmus\Pnliprp1, Mmus\Pnliprp2, Mmus\Lpl, Mmus\Lipg, Mmus\Pla1a, Mmus\Liph, Mmus\Pnlip, Mmus\Lipc" "Hsap\PNLIPRP2, Hsap\PNLIPRP3, Hsap\PLA1A, Hsap\LPL, Hsap\PNLIPRP1, Hsap\PNLIP, Hsap\LIPH, Hsap\LIPC, Hsap\LIPI, Hsap\LIPG" "viable,fertile" FBgn0054024 lncRNA:CR34024 - http://flybase.org/reports/FBgn0054024 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BP1090, HDC15672, CG34024, CR34024" - CR34024 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002285 soba suppressor of bulge and argos http://flybase.org/reports/FBgn0002285 - gene - - - "l(3)std4, l(3)73Aj, soba" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0044518 ifm(2)RU486 indirect flight muscle (2) RU486 http://flybase.org/reports/FBgn0044518 gene - - - "RU486, ifm(2)RU486" - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible,sterile,recessive,flight defective" "wing,indirect flight muscle" FBgn0267526 lncRNA:CR45866 - http://flybase.org/reports/FBgn0267526 non_protein_coding_gene - - - CR45866 - CR45866 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0028590 l(3)L4222a lethal (3) L4222a http://flybase.org/reports/FBgn0028590 gene - - - "l(3)L4222, l(3)L4222a" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0266164 lncRNA:CR44870 - http://flybase.org/reports/FBgn0266164 non_protein_coding_gene - - - CR44870 - CR44870 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0022103 l(2)k07118b lethal (2) k07118b http://flybase.org/reports/FBgn0022103 - gene - - - "l(2)k07118, l(2)k07118b, l(2)k0711b, (2)k07118b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0038492 Mur89F Mucin related 89F http://flybase.org/reports/FBgn0038492 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 extracellular matrix structural constituent ; GO:0005201 | inferred from sequence model chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 extracellular matrix ; GO:0031012 | inferred from sequence model "CT13556, Mur89F, CG4090" IPR002557:Chitin binding domain CG4090 27-Aug-18 DroID_v2018_08 "Drer\chia.2, Drer\ovgp1, Drer\chia.5, Drer\si:ch211-226m16.2" Scer\CTS2 "Cele\cbd-1, Cele\W03F11.1" "Xtro\chit1, Xtro\chia, Xtro\LOC548945, Xtro\ctbs" "Mmus\Ovgp1, Mmus\Chit1, Mmus\Chil1, Mmus\Chil3, Mmus\Ctbs, Mmus\Chil6, Mmus\Chia1, Mmus\Chil4, Mmus\Chil5" "Hsap\CHIA, Hsap\OVGP1, Hsap\CHI3L1, Hsap\CHI3L2, Hsap\CHIT1" viable DRSC15544 I 1.745683474 0.433702246 -0.635136681 -0.055825722 -0.394560534 -0.977250275 FBgn0267579 lncRNA:CR45919 - http://flybase.org/reports/FBgn0267579 non_protein_coding_gene - - - "CR45919, pri-mir-124" - CR45919 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0064153 p124 p124 http://flybase.org/reports/FBgn0064153 gene - - - "P124, p124" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0261814 lncRNA:CR42756 - http://flybase.org/reports/FBgn0261814 non_protein_coding_gene - - - CR42756 - CR42756 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0010866 l(3)05430 lethal (3) 05430 http://flybase.org/reports/FBgn0010866 - gene molecular_function ; GO:0003674 | no biological data available embryonic morphogenesis ; GO:0048598 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available l(3)05430 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,polyphasic,recessive,maternal effect,poor" "embryonic/first instar larval cuticle,maternal effect" FBgn0035816 CG13685 - http://flybase.org/reports/FBgn0035816 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13685 - CG13685 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0025773 l(3)89Ab lethal (3) 89Ab http://flybase.org/reports/FBgn0025773 - gene - - - l(3)89Ab - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005574 l(3)85Ej lethal (3) 85Ej http://flybase.org/reports/FBgn0005574 - gene - - - l(3)85Ej - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0022137 l(2)k06327 lethal (2) k06327 http://flybase.org/reports/FBgn0022137 - gene - - - l(2)k06327 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0005398 pch parched http://flybase.org/reports/FBgn0005398 "FBgn0000050, FBgn0001333, FBgn0003043, FBgn0004645" gene - - - "l(1)1Aa, lEC1, EC1, EC2, l[EC1], l(1)[d], l(1)d, l(1)HF310, l(1)7e, dmd, addB, pch" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,some die during immature adult stage" FBgn0001412 l(1)3Eb lethal (1) 3Eb http://flybase.org/reports/FBgn0001412 - gene - - - "GF332, l(1)3Eb" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" "ovary,germline clone,follicle cell" FBgn0266468 noix - http://flybase.org/reports/FBgn0266468 gene - - - noix - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,cell polarity defective,germline clone" "egg chamber,germline clone,oocyte,centrosome | germline clone" FBgn0025753 l(3)93DFi lethal (3) 93DFi http://flybase.org/reports/FBgn0025753 - gene - - - l(3)93DFi - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0069131 mei(2)yh15 mei(2)yh15 http://flybase.org/reports/FBgn0069131 gene - male meiosis chromosome segregation ; GO:0007060 | inferred from mutant phenotype - mei(2)yh15 - - 27-Aug-18 DroID_v2018_08 - - - - - - "meiotic cell cycle defective,male,recessive,female fertile" FBgn0267782 lncRNA:CR46113 - http://flybase.org/reports/FBgn0267782 non_protein_coding_gene - - - CR46113 - CR46113 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030876 CG6762 - http://flybase.org/reports/FBgn0030876 protein_coding_gene sulfiredoxin activity ; GO:0032542 | inferred from biological aspect of ancestor with PANTHER:PTN002328029 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR016692 cellular response to oxidative stress ; GO:0034599 | inferred from biological aspect of ancestor with PANTHER:PTN002328029 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN002328029 CG6762 "IPR016692:Sulfiredoxin, IPR003115:ParB/Sulfiredoxin" CG6762 27-Aug-18 DroID_v2018_08 Drer\srxn1 Scer\SRX1 - - Mmus\Srxn1 Hsap\SRXN1 viable FBgn0036938 CG14187 - http://flybase.org/reports/FBgn0036938 protein_coding_gene molecular_function ; GO:0003674 | no biological data available chorion-containing eggshell formation ; GO:0007304 | inferred from expression pattern chorion ; GO:0042600 | inferred by curator from GO:0007304 CG14187 - CG14187 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0052418 vito viriato http://flybase.org/reports/FBgn0052418 protein_coding_gene molecular_function ; GO:0003674 | no biological data available positive regulation of imaginal disc growth ; GO:0045572 | inferred from mutant phenotype eye-antennal disc development ; GO:0035214 | inferred from mutant phenotype negative regulation of apoptotic process ; GO:0043066 | inferred from mutant phenotype nucleolus organization ; GO:0007000 | inferred from mutant phenotype positive regulation of cell proliferation ; GO:0008284 | inferred from mutant phenotype positive regulation of cell growth ; GO:0030307 | inferred from mutant phenotype nucleolus ; GO:0005730 | inferred from direct assay "CG10569, vito, CG32418" IPR019186:Nucleolar protein 12 CG32418 27-Aug-18 DroID_v2018_08 "Drer\pkmyt1, Drer\wee2, Drer\wee1, Drer\nol12" "Scer\RRP17, Scer\SWE1" - "Xtro\nol12, Xtro\pkmyt1" "Mmus\Wee2, Mmus\Wee1, Mmus\Pkmyt1, Mmus\Nol12" "Hsap\WEE2, Hsap\WEE1, Hsap\PKMYT1, Hsap\NOL12" "size defective,recessive,developmental rate defective,increased cell death,decreased cell number,somatic clone,decreased cell size,viable,visible" "eye,eye disc,somatic clone | third instar larval stage,embryonic/larval salivary gland,nucleolus | third instar larval stageptc-559.1,trichogen cell" FBgn0038332 CG6136 - http://flybase.org/reports/FBgn0038332 protein_coding_gene "copper ion binding ; GO:0005507 | inferred from electronic annotation with InterPro:IPR005627, InterPro:IPR023648" "copper ion homeostasis ; GO:0055070 | inferred from electronic annotation with InterPro:IPR005627, InterPro:IPR023648 sensory perception of pain ; GO:0019233 | inferred from mutant phenotype" - CG6136 "IPR005627:Copper homeostasis protein CutC, IPR023648:Copper homeostasis CutC domain" CG6136 27-Aug-18 DroID_v2018_08 Drer\cutc - Cele\cutc-1 Xtro\cutc Mmus\Cutc Hsap\CUTC viable FBgn0266895 lncRNA:CR45355 - http://flybase.org/reports/FBgn0266895 non_protein_coding_gene - - - CR45355 - CR45355 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0061003 l(3)S026532 lethal (3) S026532 http://flybase.org/reports/FBgn0061003 gene - - - "0265/32, l(3)S026532" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0002087 l(2)52Ea lethal (2) 52Ea http://flybase.org/reports/FBgn0002087 - gene - - - "KL-32-1, l(2)52Ea" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0060997 l(3)S027114 lethal (3) S027114 http://flybase.org/reports/FBgn0060997 gene - - - "0271/14, l(3)S027114" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0032846 CG10721 - http://flybase.org/reports/FBgn0032846 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR023753 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR023753 - "38B.14, CG10721" IPR023753:FAD/NAD(P)-binding domain CG10721 27-Aug-18 DroID_v2018_08 Drer\ryroxd1 - Cele\C26D10.3 Xtro\pyroxd1 Mmus\Pyroxd1 Hsap\PYROXD1 viable FBgn0033587 CG13218 - http://flybase.org/reports/FBgn0033587 protein_coding_gene - - - CG13218 - CG13218 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0264295 CG43773 - http://flybase.org/reports/FBgn0264295 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43773, CG10039" - CG43773 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0026441 ear ENL/AF9-related http://flybase.org/reports/FBgn0026441 FBgn0038317 protein_coding_gene "transcription factor activity, core RNA polymerase II binding ; GO:0000991 | inferred from sequence or structural similarity with SGD:S000006050" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR005033 transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:7134 inferred from sequence or structural similarity with HGNC:7136 inferred from sequence or structural similarity with SGD:S000005051 inferred from sequence or structural similarity with SGD:S000006050" ELL-EAF complex ; GO:0032783 | inferred from physical interaction with Su(Tpl) inferred from physical interaction with Su(Tpl) inferred from physical interaction with Su(Tpl) inferred from physical interaction with Su(Tpl) transcription factor TFIID complex ; GO:0005669 | inferred from sequence or structural similarity with HGNC:7134 inferred from sequence or structural similarity with HGNC:7136 inferred from sequence or structural similarity with SGD:S000005051 inferred from sequence or structural similarity with SGD:S000006050 transcription factor TFIIF complex ; GO:0005674 | inferred from sequence or structural similarity with HGNC:7134 inferred from sequence or structural similarity with SGD:S000006050 "ENL/AF-9, CG4913, ENL/AF9, dENL/AF9, ear, Ear" IPR005033:YEATS CG4913 27-Aug-18 DroID_v2018_08 "Drer\yeats2, Drer\mllt1a, Drer\yeats4, Drer\mllt1b, Drer\mllt3" "Scer\FYV8, Scer\SAS5, Scer\TAF14, Scer\YAF9" - "Xtro\mllt3, Xtro\mllt1, Xtro\yeats2, Xtro\yeats4" "Mmus\Yeats4, Mmus\Mllt3, Mmus\Yeats2, Mmus\Mllt1" "Hsap\YEATS2, Hsap\MLLT3, Hsap\YEATS4, Hsap\MLLT1" viable DRSC15675 E 1.017548008 0.815218848 2.45208999 1.647138559 -1.044325768 -0.264757704 FBgn0065205 l(2)SH2280 lethal (2) SH2280 http://flybase.org/reports/FBgn0065205 gene - - - "l(2)SH2280, l(2)SH2 2280" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0265821 lncRNA:CR44610 - http://flybase.org/reports/FBgn0265821 non_protein_coding_gene - - - CR44610 - CR44610 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0015000 betaggt-I beta subunit of type I geranylgeranyl transferase http://flybase.org/reports/FBgn0015000 - protein_coding_gene CAAX-protein geranylgeranyltransferase activity ; GO:0004662 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000206684 protein geranylgeranyltransferase activity ; GO:0004661 | inferred from sequence or structural similarity with protein_id:AAA35888.1 inferred from sequence or structural similarity with protein_id:CAA78143.1 neurogenesis ; GO:0022008 | inferred from mutant phenotype protein geranylgeranylation ; GO:0018344 | inferred from biological aspect of ancestor with PANTHER:PTN000206684 positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from genetic interaction with Ras85D embryonic heart tube development ; GO:0035050 | inferred from mutant phenotype positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with Ras85D CAAX-protein geranylgeranyltransferase complex ; GO:0005953 | inferred from biological aspect of ancestor with PANTHER:PTN000206684 "GGT1, beta GGT-I, beta-GGT, betaGGT-I, ggt1, SR2-2, betaggt-I, ggt-1, CG3469, bro3, betaGGTI, ggt-I, betaggt, betaGGT" "IPR001330:PFTB repeat, IPR008930:Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid" CG3469 27-Aug-18 DroID_v2018_08 Drer\pggt1b "Scer\BET2, Scer\CDC43" Cele\Y48E1B.3 Xtro\pggt1b Mmus\Pggt1b Hsap\PGGT1B "lethal,recessive,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic pericardial cell,cardioblast,embryonic/larval neuroblast,ganglion mother cell" FBgn0041099 ppo poco pelo http://flybase.org/reports/FBgn0041099 gene - - - "EP2478, ppo" - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,wild-type,recessive,somatic clone,lethal - all die before end of embryonic stage,some die during embryonic stage" "macrochaeta,microchaeta,thecogen cell,ectopic,tormogen cell,trichogen cell,wing margin,scutellum,wing margin bristle,supernumerary,somatic clone,adult thoracic sensillum" FBgn0001805 l(1)Mc35 lethal (1) Mc35 http://flybase.org/reports/FBgn0001805 - gene - - - l(1)Mc35 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0031045 CG14212 - http://flybase.org/reports/FBgn0031045 protein_coding_gene phosphatase activity ; GO:0016791 | inferred from biological aspect of ancestor with PANTHER:PTN000467154 pyrophosphatase activity ; GO:0016462 | inferred from sequence or structural similarity with HGNC:16815 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG14212, CG14122, 19527979" "IPR006384:Pyridoxal phosphate phosphatase-related, IPR016965:Phosphatase PHOSPHO-type, IPR023214:HAD-like domain" CG14212 27-Aug-18 DroID_v2018_08 "Drer\phospho2, Drer\phospho1" - "Cele\irld-56, Cele\irld-39, Cele\irld-64, Cele\irld-49, Cele\irld-67, Cele\irld-60, Cele\hpa-1, Cele\irld-51" Xtro\phospho2 "Mmus\Phospho1, Mmus\Phospho2" "Hsap\PHOSPHO2, Hsap\PHOSPHO1" "viable,fertile" FBgn0264551 lncRNA:CR43930 - http://flybase.org/reports/FBgn0264551 non_protein_coding_gene - - - CR43930 - CR43930 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002107 l(2)64 lethal (2) 64 http://flybase.org/reports/FBgn0002107 - gene - - - l(2)64 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0082669 GS2143 GS2143 http://flybase.org/reports/FBgn0082669 gene - - - GS2143 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0027514 CG1024 - http://flybase.org/reports/FBgn0027514 - protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 neurogenesis ; GO:0022008 | inferred from mutant phenotype - "BcDNA:LD21969, CG1024" "IPR013087:Zinc finger C2H2-type, IPR022755:Zinc finger, double-stranded RNA binding" CG1024 27-Aug-18 DroID_v2018_08 "Drer\si:dkey-154p10.3, Drer\ctcf" Scer\PZF1 - - "Mmus\Ctcf, Mmus\Ctcfl" "Hsap\CTCFL, Hsap\CTCF" "lethal,neuroanatomy defective,visible,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum" DRSC12496 K 1.282010376 -0.715777293 1.405237754 -1.309526606 -2.017089235 -0.674651051 FBgn0035239 CG18170 - http://flybase.org/reports/FBgn0035239 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG32316, CG18170" "IPR032106:2-oxoglutarate dehydrogenase E1 component, N-terminal domain" CG18170 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265309 lncRNA:CR44282 - http://flybase.org/reports/FBgn0265309 non_protein_coding_gene - - - CR44282 - CR44282 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264785 Hph HIF prolyl hydroxylase http://flybase.org/reports/FBgn0264785 protein_coding_gene "L-ascorbic acid binding ; GO:0031418 | inferred from electronic annotation with InterPro:IPR006620 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR006620 iron ion binding ; GO:0005506 | inferred from sequence model peptidyl-proline 4-dioxygenase activity ; GO:0031545 | inferred from sequence or structural similarity with HGNC:1232,HGNC:14660,HGNC:14661 zinc ion binding ; GO:0008270 | inferred from sequence model with Pfam:PF01753 peptidyl-proline dioxygenase activity ; GO:0031543 | inferred from direct assay" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005123, InterPro:IPR006620 terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype positive regulation of cell growth ; GO:0030307 | inferred from genetic interaction with CycD, Cdk4 positive regulation of cell growth ; GO:0030307 | inferred from mutant phenotype cellular response to hypoxia ; GO:0071456 | inferred from mutant phenotype cellular response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype protein localization ; GO:0008104 | inferred from mutant phenotype peptidyl-proline hydroxylation ; GO:0019511 | inferred from direct assay response to hypoxia ; GO:0001666 | inferred from mutant phenotype trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype peptidyl-proline hydroxylation to 4-hydroxy-L-proline ; GO:0018401 | inferred from sequence or structural similarity with HGNC:1232,HGNC:14660,HGNC:14661 protein export from nucleus ; GO:0006611 | inferred from mutant phenotype" nucleoplasm ; GO:0005654 | inferred from direct assay "Hph, PHD, hph, dPHD, CG44015, CG31543, dPHD2, fga, CG14665, l(3)02255, CG1114, dmHPH, Dm.egl-9, 0303/04, anon-EST:Posey69, l(3)S030304, dHPH, 31543, l(3)82Fe, CG2676, CR31541, fatiga, FgaB" "IPR006620:Prolyl 4-hydroxylase, alpha subunit, IPR005123:Oxoglutarate/iron-dependent dioxygenase, IPR002893:Zinc finger, MYND-type" CG44015 27-Aug-18 DroID_v2018_08 "Drer\egln1a, Drer\taf5, Drer\egln2, Drer\egln1b, Drer\egln3" - Cele\egl-9 "Xtro\taf5l, Xtro\egln3, Xtro\taf5, Xtro\egln1, Xtro\egln2" "Mmus\Egln2, Mmus\Egln1, Mmus\Taf5l, Mmus\Egln3, Mmus\Taf5" "Hsap\EGLN3, Hsap\TAF5, Hsap\EGLN2, Hsap\EGLN1, Hsap\TAF5L" FBgn0064155 oosy out of sync http://flybase.org/reports/FBgn0064155 gene - nuclear axial expansion ; GO:0035191 | inferred from mutant phenotype nuclear cortical migration ; GO:0035192 | inferred from mutant phenotype regulation of preblastoderm mitotic cell cycle ; GO:0007347 | inferred from mutant phenotype - oosy - - 27-Aug-18 DroID_v2018_08 - - - - - - "pole cell,maternal effect,cleavage nucleus,germline clone" FBgn0266535 lncRNA:CR45096 - http://flybase.org/reports/FBgn0266535 non_protein_coding_gene - - - CR45096 - CR45096 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0053902 His2B:CG33902 His2B:CG33902 http://flybase.org/reports/FBgn0053902 protein_coding_gene protein heterodimerization activity ; GO:0046982 | inferred from electronic annotation with InterPro:IPR009072 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 chromatin assembly or disassembly ; GO:0006333 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 nuclear nucleosome ; GO:0000788 | inferred from sequence or structural similarity with SGD_LOCUS:HTB1; SGD:S000002632 "CG33902, His2B:CG33902" "IPR009072:Histone-fold, IPR000558:Histone H2B, IPR007125:Histone H2A/H2B/H3" CG33902 27-Aug-18 DroID_v2018_08 "Drer\LOC100329560, Drer\LOC100329290, Drer\si:ch1073-159d7.13, Drer\hist2h2l, Drer\si:dkey-108k21.27, Drer\si:ch211-113a14.28, Drer\si:ch1073-153i20.3, Drer\zgc:194989, Drer\si:dkey-261m9.19, Drer\ano9a, Drer\si:ch1073-159d7.5, Drer\si:ch211-113a14.29, Drer\si:dkey-23a13.1, Drer\si:ch73-368j24.8, Drer\zgc:173587, Drer\si:dkey-261m9.6, Drer\si:dkey-108k21.11, Drer\si:ch73-36p18.3, Drer\zgc:114046, Drer\zgc:173585, Drer\LOC100334559, Drer\si:ch211-113a14.11, Drer\LOC100334869, Drer\si:dkey-23a13.5, Drer\hist1h2ba, Drer\si:dkey-23a13.16, Drer\zgc:92591" "Scer\HTB2, Scer\HTB1" "Cele\his-20, Cele\his-66, Cele\his-4, Cele\his-8, Cele\his-41, Cele\his-54, Cele\his-15, Cele\his-48, Cele\his-58, Cele\his-22, Cele\his-39, Cele\his-11, Cele\his-29, Cele\his-62, Cele\his-44, Cele\his-34, Cele\his-52" "Xtro\LOC101731959, Xtro\LOC100498647, Xtro\LOC100486870, Xtro\LOC101733171, Xtro\LOC100496445, Xtro\hist1h2bj, Xtro\LOC100487485, Xtro\LOC100495041, Xtro\LOC100496436, Xtro\hist1h2bm, Xtro\LOC101734862, Xtro\LOC101731067, Xtro\LOC100496181, Xtro\LOC100485294, Xtro\LOC101733489, Xtro\LOC100497915, Xtro\hist2h2be, Xtro\LOC100486150, Xtro\hist1h2bk, Xtro\LOC100495578, Xtro\LOC101735164, Xtro\LOC100497082, Xtro\LOC100492632, Xtro\LOC101731852, Xtro\LOC101735218, Xtro\LOC100495396, Xtro\LOC100498072, Xtro\LOC100495415, Xtro\LOC101733828, Xtro\LOC100498329, Xtro\LOC100498553, Xtro\LOC100485134, Xtro\LOC101734494, Xtro\LOC101730940" "Mmus\Hist2h2be, Mmus\Hist1h2bn, Mmus\Hist1h2bh, Mmus\Hist1h2bq, Mmus\Hist1h2bp, Mmus\Hist1h2bf, Mmus\Hist1h2ba, Mmus\Hist1h2bj, Mmus\Hist1h2bk, Mmus\Hist1h2br, Mmus\Hist1h2bb, Mmus\Hist1h2bc, Mmus\Hist3h2ba, Mmus\Hist2h2bb, Mmus\Hist1h2be, Mmus\Hist1h2bm, Mmus\Hist1h2bl, Mmus\H2bfm, Mmus\1700024P04Rik, Mmus\Hist1h2bg" "Hsap\HIST1H2BM, Hsap\H2BFM, Hsap\HIST1H2BA, Hsap\HIST1H2BF, Hsap\HIST3H2BB, Hsap\HIST2H2BE, Hsap\HIST2H2BF, Hsap\HIST1H2BL, Hsap\HIST1H2BG, Hsap\HIST1H2BO, Hsap\HIST1H2BI, Hsap\H2BFWT, Hsap\HIST1H2BC, Hsap\HIST1H2BE, Hsap\HIST1H2BN, Hsap\HIST1H2BD, Hsap\HIST1H2BJ, Hsap\HIST1H2BH, Hsap\HIST1H2BB, Hsap\HIST1H2BK" FBgn0033132 Tsp42Ej Tetraspanin 42Ej http://flybase.org/reports/FBgn0033132 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cellular response to high light intensity ; GO:0071486 | inferred from mutant phenotype endocytosis ; GO:0006897 | inferred from mutant phenotype cell surface receptor signaling pathway ; GO:0007166 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 integral component of membrane ; GO:0016021 | inferred from sequence model lysosome ; GO:0005764 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001060286 "sun, CG12143, Sun, Dm.Tsp42Ej, Tsp42Ej, tsp42ej" "IPR018499:Tetraspanin/Peripherin, IPR008952:Tetraspanin, EC2 domain" CG12143 27-Aug-18 DroID_v2018_08 "Drer\si:ch73-139j3.4, Drer\tspan37" - Cele\tsp-13 Xtro\LOC100145428 - "Hsap\TSPAN19, Hsap\TSPAN16, Hsap\TSPAN6" "viable,fertile,visible" "retina,trichogen cell" FBgn0264524 ff18 - http://flybase.org/reports/FBgn0264524 gene - - - ff18 - - 27-Aug-18 DroID_v2018_08 - - - - - - "meiotic cell cycle defective,male" spermatid FBgn0065655 l(2)SH0723 lethal (2) SH0723 http://flybase.org/reports/FBgn0065655 gene - - - l(2)SH0723 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0016123 Alp4 Alkaline phosphatase 4 http://flybase.org/reports/FBgn0016123 FBgn0010913 protein_coding_gene alkaline phosphatase activity ; GO:0004035 | inferred from sequence or structural similarity with HGNC:439 dephosphorylation ; GO:0016311 | inferred from sequence or structural similarity with HGNC:439 epithelial fluid transport ; GO:0042045 | inferred from mutant phenotype multicellular organism reproduction ; GO:0032504 | inferred from expression pattern nervous system development ; GO:0007399 | inferred from expression pattern extracellular region ; GO:0005576 | inferred from sequence model cell surface ; GO:0009986 | inferred from sequence or structural similarity with HGNC:439 extracellular space ; GO:0005615 | inferred from sequence model "CG1462, pMY51, l(3)07028, aph-4, Aph-4, Alp4" "IPR001952:Alkaline phosphatase, IPR018299:Alkaline phosphatase, active site, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha, IPR017850:Alkaline-phosphatase-like, core domain" CG1462 27-Aug-18 DroID_v2018_08 "Drer\alpi.1, Drer\alpl, Drer\alpi.2, Drer\alp3" Scer\PHO8 - "Xtro\alpi.1, Xtro\alpl" "Mmus\Alpi, Mmus\Alppl2, Mmus\Alpl, Mmus\Akp3" "Hsap\ALPL, Hsap\ALPPL2, Hsap\ALPI, Hsap\ALPP" " adult stage , larval stage && adult stage " " Malpighian tubule

, ellipsoid body

" "viable,partially lethal - majority die,recessive,lethal" adult Malpighian tubule FBgn0267017 lncRNA:CR45461 - http://flybase.org/reports/FBgn0267017 non_protein_coding_gene - - - CR45461 - CR45461 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040109 l(3)tk21 lethal (3) tk21 http://flybase.org/reports/FBgn0040109 gene - - - "tk21, l(3)tk21" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0060897 l(3)S044306 lethal (3) S044306 http://flybase.org/reports/FBgn0060897 gene - - - "0443/06, l(3)S044306" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0261918 EndoA::Hsap\ARFIP2 - http://flybase.org/reports/FBgn0261918 engineered_fusion_gene - - - "endoA::Hsap\ARFIP2, EndoA::Hsap\ARFIP2" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004483 l(1)air10 lethal aberrant immune response 10 http://flybase.org/reports/FBgn0004483 - gene - - - "air10, l(1)air10" - - 27-Aug-18 DroID_v2018_08 - - - - - - "melanotic mass phenotype,lethal - all die before end of larval stage,recessive,some die during larval stage" "embryonic/larval brain,embryonic/larval hindgut,melanotic mass" FBgn0052856 CG32856 - http://flybase.org/reports/FBgn0052856 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR029138 molecular_function ; GO:0003674 | no biological data available" transcription from RNA polymerase II promoter ; GO:0006366 | inferred from electronic annotation with InterPro:IPR029138 transcription initiation from RNA polymerase III promoter ; GO:0006384 | inferred from electronic annotation with InterPro:IPR029138 biological_process ; GO:0008150 | no biological data available nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR029138 cellular_component ; GO:0005575 | no biological data available "BcDNA:GM32296, CG32856" IPR029138:snRNA-activating protein complex subunit 5 CG32856 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040038 klhl10 kelch like family member 10 http://flybase.org/reports/FBgn0040038 protein_coding_gene - sperm individualization ; GO:0007291 | inferred from mutant phenotype activation of cysteine-type endopeptidase activity involved in apoptotic process ; GO:0006919 | inferred from mutant phenotype protein ubiquitination ; GO:0016567 | inferred from mutant phenotype Cul3-RING ubiquitin ligase complex ; GO:0031463 | inferred from physical interaction with Cul3 "anon-WO0140519.152, CG12423, klhl10" "IPR000210:BTB/POZ domain, IPR011705:BTB/Kelch-associated, IPR011333:SKP1/BTB/POZ domain, IPR006652:Kelch repeat type 1, IPR015916:Galactose oxidase, beta-propeller, IPR015915:Kelch-type beta propeller" CG12423 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-253p14.2, Drer\LOC101882758, Drer\klhdc8a, Drer\kbtbd11, Drer\klhdc8b, Drer\klhl10b.1, Drer\klhl10a, Drer\klhl32, Drer\klhl11, Drer\klhl42, Drer\klhl10b.2" - "Cele\C53A5.9, Cele\kel-10, Cele\C53A5.11, Cele\C53A5.6, Cele\spe-26, Cele\F47D12.7" "Xtro\klhl10, Xtro\kbtbd13, Xtro\klhdc8a, Xtro\klhdc8b, Xtro\kbtbd11, Xtro\klhl32" "Mmus\Klhl33, Mmus\Klhl11, Mmus\Klhl42, Mmus\Klhdc8b, Mmus\Klhl32, Mmus\Klhl10, Mmus\Kbtbd13, Mmus\Klhdc8a, Mmus\Klhdc7a, Mmus\Klhdc7b, Mmus\Kbtbd11" "Hsap\KLHL32, Hsap\KLHDC7B, Hsap\KLHL42, Hsap\KLHDC8B, Hsap\KBTBD11, Hsap\KLHL33, Hsap\KBTBD13, Hsap\KLHL10, Hsap\KLHDC7A, Hsap\KLHDC8A, Hsap\KLHL11" "viable,visible,male sterile,recessive" "eye,ommatidium,spermatid" DRSC20925 I 1.728214047 0.063898099 -0.681175424 0.391517731 FBgn0011194 l(1)302-3 lethal (1) 302-3 http://flybase.org/reports/FBgn0011194 FBgn0010202 gene - - - "302-3, l(1)302-3" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0263886 l(3)C26 - http://flybase.org/reports/FBgn0263886 gene - - - l(3)C26 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,cell cycle defective,somatic clone" "embryonic/larval brain,somatic clone,embryonic/larval neuroblast" FBgn0043050 anon-50Ea anon-50Ea http://flybase.org/reports/FBgn0043050 gene - - - "t2, T2, anon-50Ea" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265964 lncRNA:CR44751 - http://flybase.org/reports/FBgn0265964 non_protein_coding_gene - - - CR44751 - CR44751 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260279 GSd496 - http://flybase.org/reports/FBgn0260279 gene - - - GSd496 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve,segmental nerve" FBgn0001171 ha hair bristles http://flybase.org/reports/FBgn0001171 - gene - - - ha - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,male,female,reduced,male fertile,female sterile,recessive,visible" macrochaeta FBgn0005141 l(2)CA6 lethal (2) CA6 http://flybase.org/reports/FBgn0005141 - gene - - - "l(2)br6, l(1)br6, l(2)CA6" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0259979 CG17337 - http://flybase.org/reports/FBgn0259979 protein_coding_gene dipeptidase activity ; GO:0016805 | inferred from electronic annotation with InterPro:IPR017153 metallopeptidase activity ; GO:0008237 | inferred from electronic annotation with InterPro:IPR001261 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001261 extracellular region ; GO:0005576 | inferred from direct assay "CG17337, Y, anon-41Fb, Dm52" "IPR001261:ArgE/DapE/ACY1/CPG2/YscS, conserved site, IPR002933:Peptidase M20, IPR011650:Peptidase M20, dimerisation domain, IPR017153:Cytosolic nonspecific dipeptidase/DUG1" CG17337 27-Aug-18 DroID_v2018_08 "Drer\cndp2, Drer\zgc:114181" "Scer\DUG1, Scer\DUG2" "Cele\pes-9, Cele\Y71H2AM.11" "Xtro\cndp2, Xtro\cndp1, Xtro\darmin" "Mmus\Cndp1, Mmus\Cndp2" "Hsap\CNDP1, Hsap\CNDP2" embryonic stage embryonic/larval digestive system

FBgn0026619 Taz Tafazzin http://flybase.org/reports/FBgn0026619 - protein_coding_gene "phosphatidylcholine:cardiolipin O-linoleoyltransferase activity ; GO:0032577 | inferred from direct assay transferase activity, transferring acyl groups ; GO:0016746 | inferred from direct assay" cardiolipin metabolic process ; GO:0032048 | inferred from direct assay cardiolipin acyl-chain remodeling ; GO:0035965 | inferred from biological aspect of ancestor with PANTHER:PTN000281558 cardiolipin biosynthetic process ; GO:0032049 | inferred from mutant phenotype mitochondrial membrane organization ; GO:0007006 | inferred from direct assay inner mitochondrial membrane organization ; GO:0007007 | inferred from biological aspect of ancestor with PANTHER:PTN000281558 phospholipid metabolic process ; GO:0006644 | inferred by curator from GO:0032577 sperm individualization ; GO:0007291 | inferred from mutant phenotype phospholipid metabolic process ; GO:0006644 | inferred from direct assay mitochondrial membrane ; GO:0031966 | inferred from biological aspect of ancestor with PANTHER:PTN000281558 intrinsic component of membrane ; GO:0031224 | inferred from biological aspect of ancestor with PANTHER:PTN000281557 mitochondrion ; GO:0005739 | inferred from direct assay "CG8766, Taz, tafazzin, dTAZ, TAZ" "IPR000872:Tafazzin, IPR002123:Phospholipid/glycerol acyltransferase" CG8766 27-Aug-18 DroID_v2018_08 Drer\taz Scer\TAZ1 Cele\acl-3 Xtro\taz Mmus\Taz Hsap\TAZ "locomotor behavior defective,male sterile,recessive,viable,body color defective" "indirect flight muscle & mitochondrion,mitochondrial crista,mitochondrion,individualization stage spermatid,spermatid cyst,mesothoracic tergum" FBgn0030467 CG1764 - http://flybase.org/reports/FBgn0030467 protein_coding_gene - - - "CG1764, cg1764" IPR033199:Dimethylarginine dimethylaminohydrolase/arginine deiminase CG1764 27-Aug-18 DroID_v2018_08 "Drer\ddah1, Drer\ddah2" - "Cele\ZK1307.1, Cele\fbxa-11, Cele\T22B7.3" "Xtro\ddah2, Xtro\ddah1" "Mmus\Ddah2, Mmus\Ddah1" "Hsap\DDAH1, Hsap\DDAH2" "viable,fertile" FBgn0065350 l(2)SH1806 lethal (2) SH1806 http://flybase.org/reports/FBgn0065350 gene - - - "l(2)SH1806, l(2)SH2 1806" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0027788 Hey Hairy/E(spl)-related with YRPW motif http://flybase.org/reports/FBgn0027788 FBgn0027789 protein_coding_gene protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with UniProtKB:Q9QUS4 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR003650 negative regulation of Notch signaling pathway ; GO:0045746 | inferred from sequence or structural similarity with UniProtKB:Q9QUS4 neuron fate determination ; GO:0048664 | inferred from mutant phenotype" nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q9QUS4 "Hey, d-hey, CG11194, Hesr-1, dHey, hesr-1, hey, bHLHe44, HEY" "IPR003650:Orange domain, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG11194 27-Aug-18 DroID_v2018_08 "Drer\her9, Drer\her8.2, Drer\heyl, Drer\her8a, Drer\hes6, Drer\helt, Drer\hes2.1, Drer\hey1, Drer\her5, Drer\hey2, Drer\her11, Drer\her1, Drer\bhlhe41, Drer\her6, Drer\bhlhe40, Drer\her13, Drer\hes2.2" Scer\PHO4 Cele\lin-22 "Xtro\hey1, Xtro\bhlhe41, Xtro\hes7.1, Xtro\hes2, Xtro\hes1, Xtro\hes6.1, Xtro\hey2, Xtro\hes4, Xtro\hes7.2, Xtro\bhlhe40" "Mmus\Heyl, Mmus\Bhlhe41, Mmus\Hey2, Mmus\Hes7, Mmus\Helt, Mmus\Bhlhe40, Mmus\Hey1, Mmus\Hes6, Mmus\Hes1, Mmus\Hes2" "Hsap\HEY1, Hsap\HELT, Hsap\HEYL, Hsap\HES6, Hsap\BHLHE41, Hsap\HEY2, Hsap\HES1, Hsap\HES2, Hsap\HES4, Hsap\BHLHE40" "lethal - all die before end of second instar larval stage,some die during embryonic stage,majority die during first instar larval stage,neuroanatomy defective" "RP2 motor neuron,RP2sib neuron,dMP2 neuron,vMP2 neuron" FBgn0265151 lncRNA:CR44220 - http://flybase.org/reports/FBgn0265151 non_protein_coding_gene - - - CR44220 - CR44220 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266322 asRNA:CR44987 - http://flybase.org/reports/FBgn0266322 non_protein_coding_gene - - - CR44987 - CR44987 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0011316 l(3)j1D5 lethal (3) j1D5 http://flybase.org/reports/FBgn0011316 - gene - - - l(3)j1D5 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0262999 CG43307 - http://flybase.org/reports/FBgn0262999 protein_coding_gene - - - "CG43307, lincRNA.52" IPR002350:Kazal domain CG43307 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039151 CG13607 - http://flybase.org/reports/FBgn0039151 protein_coding_gene - - - "CG13607, 150482_at" - CG13607 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060994 l(3)S027318b lethal (3) S027318b http://flybase.org/reports/FBgn0060994 gene - - - "0273/18, l(3)S027318b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0036791 CG7271 - http://flybase.org/reports/FBgn0036791 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - CG7271 IPR013087:Zinc finger C2H2-type CG7271 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0250744 l(3)S139908 lethal (3) S139908 http://flybase.org/reports/FBgn0250744 gene - - - "l(3)S139908, l(3)s139908" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0067358 l(3)4106 lethal (3) 4106 http://flybase.org/reports/FBgn0067358 gene - - - l(3)4106 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0020327 anon-72Da anon-72Da http://flybase.org/reports/FBgn0020327 - gene - - - "5B3, anon-72Da" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034712 CG3264 - http://flybase.org/reports/FBgn0034712 protein_coding_gene alkaline phosphatase activity ; GO:0004035 | inferred from sequence or structural similarity with HGNC:439 dephosphorylation ; GO:0016311 | inferred from sequence or structural similarity with HGNC:439 cell surface ; GO:0009986 | inferred from sequence or structural similarity with HGNC:439 CG3264 "IPR001952:Alkaline phosphatase, IPR018299:Alkaline phosphatase, active site, IPR017849:Alkaline phosphatase-like, alpha/beta/alpha, IPR017850:Alkaline-phosphatase-like, core domain" CG3264 27-Aug-18 DroID_v2018_08 "Drer\alpi.1, Drer\alp3, Drer\alpi.2, Drer\alpl" Scer\PHO8 - "Xtro\alpl, Xtro\alpi.1" "Mmus\Akp3, Mmus\Alpl, Mmus\Alppl2, Mmus\Alpi" "Hsap\ALPL, Hsap\ALPPL2, Hsap\ALPI, Hsap\ALPP" viable FBgn0261864 lzb lazybones http://flybase.org/reports/FBgn0261864 gene - larval foraging behavior ; GO:0035177 | inferred from mutant phenotype - lzb - - 27-Aug-18 DroID_v2018_08 - - - - - - "behavior defective,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0034173 CG9010 - http://flybase.org/reports/FBgn0034173 protein_coding_gene "oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor ; GO:0016620 | inferred from electronic annotation with InterPro:IPR006424, InterPro:IPR020828, InterPro:IPR020829, InterPro:IPR020830, InterPro:IPR020831 NADP binding ; GO:0050661 | inferred from electronic annotation with InterPro:IPR006424 NAD binding ; GO:0051287 | inferred from electronic annotation with InterPro:IPR006424" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006424, InterPro:IPR020828, InterPro:IPR020829, InterPro:IPR020830, InterPro:IPR020831 glucose metabolic process ; GO:0006006 | inferred from electronic annotation with InterPro:IPR006424" - "anon-WO0140519.132, CG9010" "IPR006424:Glyceraldehyde-3-phosphate dehydrogenase, type I, IPR020828:Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain, IPR020829:Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain, IPR020830:Glyceraldehyde 3-phosphate dehydrogenase, active site, IPR020831:Glyceraldehyde/Erythrose phosphate dehydrogenase family, IPR016040:NAD(P)-binding domain" CG9010 27-Aug-18 DroID_v2018_08 "Drer\gapdh, Drer\gapdhs" "Scer\TDH2, Scer\TDH3, Scer\TDH1" "Cele\gpd-4, Cele\gpd-1, Cele\gpd-2, Cele\gpd-3" - "Mmus\Gapdh-ps15, Mmus\Pnmal2, Mmus\Gapdhs, Mmus\Gapdh" "Hsap\GAPDH, Hsap\PNMAL2, Hsap\GAPDHS" viable FBgn0266402 asRNA:CR45042 - http://flybase.org/reports/FBgn0266402 non_protein_coding_gene - - - CR45042 - CR45042 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259647 B0091 - http://flybase.org/reports/FBgn0259647 gene - - - B0091 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible wing FBgn0001029 Fs(3)Bak Female sterile (3) Baksa http://flybase.org/reports/FBgn0001029 - gene molecular_function ; GO:0003674 | no biological data available embryo development ending in birth or egg hatching ; GO:0009792 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "Bak, Fs(3)Baksa, Fs(3)Sz3, Fs(3)Bak" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,dominant,maternal effect,some die during embryonic stage" FBgn0086215 jhu2388 - http://flybase.org/reports/FBgn0086215 gene - - - jhu2388 - - 27-Aug-18 DroID_v2018_08 - - - - - - "presumptive embryonic salivary gland,circular visceral muscle primordium" FBgn0050083 CG30083 - http://flybase.org/reports/FBgn0050083 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" - CG30083 "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG30083 27-Aug-18 DroID_v2018_08 "Drer\tmprss13a, Drer\si:dkey-21e2.15, Drer\si:dkey-21e2.7, Drer\si:ch211-165b19.9, Drer\LOC100331291, Drer\tmprss13b, Drer\si:dkey-21e2.12, Drer\si:ch211-165b19.5, Drer\gzm3" - "Cele\try-1, Cele\try-3" - "Mmus\Gzmg, Mmus\Klk1b5, Mmus\Gzmd, Mmus\Egfbp2, Mmus\Tmprss11c, Mmus\Gzme, Mmus\Mcpt9, Mmus\Mcpt4, Mmus\Ctsg, Mmus\Tmprss11e, Mmus\Mcpt1, Mmus\Cma2, Mmus\Tmprss11b, Mmus\Prss57, Mmus\Prss40, Mmus\Klk6, Mmus\Gzmc, Mmus\Mcpt8, Mmus\Prss39, Mmus\Gzmf, Mmus\Cma1, Mmus\Tmprss11d, Mmus\Gzmb, Mmus\Prss45" "Hsap\TMPRSS11D, Hsap\CTSG, Hsap\PRSS45, Hsap\GZMB, Hsap\TMPRSS11E, Hsap\CMA1, Hsap\GZMH, Hsap\TMPRSS11B, Hsap\PRSS57" viable FBgn0026201 mog mogura http://flybase.org/reports/FBgn0026201 - gene - - - "mgr, mog" - - 27-Aug-18 DroID_v2018_08 - - - - - - "radiation sensitive,visible" eye FBgn0030055 CG12772 - http://flybase.org/reports/FBgn0030055 protein_coding_gene molecular_function ; GO:0003674 | no biological data available negative regulation of autophagy ; GO:0010507 | inferred from sequence or structural similarity with HGNC:28991 early endosome ; GO:0005769 | inferred from sequence or structural similarity with HGNC:28991 "CG12772, FBgn 30055" "IPR025258:Putative zinc-RING and/or ribbon, IPR015943:WD40/YVTN repeat-like-containing domain" CG12772 27-Aug-18 DroID_v2018_08 "Drer\rufy2, Drer\def8, Drer\si:ch211-260b17.6, Drer\rundc3ab, Drer\rundc3aa, Drer\rubcn, Drer\snx29, Drer\rundc3b, Drer\rufy1, Drer\plekhm3" - Cele\Y56A3A.16 "Xtro\rufy1, Xtro\snx29, Xtro\rundc3b, Xtro\rundc3a, Xtro\rufy3, Xtro\plekhm3, Xtro\rufy2" "Mmus\Snx29, Mmus\Rufy3, Mmus\Plekhm3, Mmus\Rufy1, Mmus\Def8, Mmus\Rubcnl, Mmus\Rufy2, Mmus\Rubcn, Mmus\Rundc3b, Mmus\Rundc3a" "Hsap\PLEKHM3, Hsap\RUNDC3B, Hsap\RUFY1, Hsap\DEF8, Hsap\RUFY2, Hsap\SNX29, Hsap\RUFY3, Hsap\RUBCN, Hsap\RUBCNL, Hsap\RUNDC3A" "viable,fertile" FBgn0024620 meso3 meso3 http://flybase.org/reports/FBgn0024620 FBgn0024480 gene - - - "Clone3, meso3" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259111 Ndae1 Na[+]-driven anion exchanger 1 http://flybase.org/reports/FBgn0259111 protein_coding_gene "inorganic anion exchanger activity ; GO:0005452 | inferred from electronic annotation with InterPro:IPR001717, InterPro:IPR003020, InterPro:IPR003024 anion:anion antiporter activity ; GO:0015301 | inferred from direct assay" proton transport ; GO:0015992 | inferred from direct assay regulation of intracellular pH ; GO:0051453 | inferred from biological aspect of ancestor with PANTHER:PTN000894242 sodium ion transport ; GO:0006814 | inferred from direct assay bicarbonate transport ; GO:0015701 | inferred from direct assay anion transport ; GO:0006820 | inferred from direct assay chloride transport ; GO:0006821 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000894242 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "CG4675, Ndae1, CG42253, 153385_at, ndae1, NDAE1, l(2)k10316, Ndae-1, anon-WO0257455.13, CG31906" "IPR003020:Bicarbonate transporter, eukaryotic, IPR003024:Sodium bicarbonate cotransporter, IPR011531:Bicarbonate transporter, C-terminal, IPR013769:Band 3 cytoplasmic domain, IPR016152:Phosphotransferase/anion transporter, IPR001717:Anion exchange protein" CG42253 27-Aug-18 DroID_v2018_08 "Drer\slc4a5, Drer\nek10, Drer\slc4a8, Drer\slc4a4b, Drer\slc4a2b, Drer\LOC557642, Drer\slc4a2a, Drer\slc4a10a, Drer\slc4a1a, Drer\slc4a4a, Drer\si:ch211-48m9.1, Drer\slc4a7, Drer\slc4a11, Drer\slc4a1b, Drer\slc4a3" Scer\BOR1 "Cele\abts-3, Cele\abts-2, Cele\abts-4, Cele\abts-1" "Xtro\slc4a7, Xtro\slc4a10, Xtro\slc4a4, Xtro\slc4a8, Xtro\slc4a3, Xtro\slc4a1, Xtro\slc4a5, Xtro\nek10, Xtro\slc4a11" "Mmus\Slc4a1, Mmus\Slc4a3, Mmus\Nek10, Mmus\Slc4a5, Mmus\Slc4a9, Mmus\Slc4a4, Mmus\Slc4a2, Mmus\Slc4a11, Mmus\Slc4a8, Mmus\Slc4a7, Mmus\Slc4a10" "Hsap\NEK10, Hsap\SLC4A1, Hsap\SLC4A10, Hsap\SLC4A8, Hsap\SLC4A9, Hsap\SLC4A11, Hsap\SLC4A7, Hsap\SLC4A2, Hsap\SLC4A5, Hsap\SLC4A3, Hsap\SLC4A4" FBgn0053732 snmRNA:430f snmRNA:430:CR33732 http://flybase.org/reports/FBgn0053732 non_protein_coding_gene - - - "CR33732, snmRNA:430:CR33732" - CR33732 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000326 clt cricklet http://flybase.org/reports/FBgn0000326 "FBgn0027353, FBgn0034640" protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | non-traceable author statement carboxylic ester hydrolase activity ; GO:0052689 | inferred from biological aspect of ancestor with PANTHER:PTN000168392 male mating behavior ; GO:0060179 | inferred from mutant phenotype imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype - "CG9858, anon-57Fb, clt, Est-R" "IPR002018:Carboxylesterase, type B, IPR019819:Carboxylesterase type B, conserved site, IPR029058:Alpha/Beta hydrolase fold" CG9858 27-Aug-18 DroID_v2018_08 "Drer\ces2, Drer\nlgn4a, Drer\si:ch211-93f2.1, Drer\nlgn2a, Drer\cel.1, Drer\ces3, Drer\nlgn3b, Drer\nlgn2b, Drer\nlgn1, Drer\nlgn4b, Drer\cell, Drer\nlgn3a" - "Cele\C52A10.1, Cele\F56C11.6, Cele\B0238.7, Cele\F13H6.3, Cele\C17H12.4, Cele\T28C12.4, Cele\K07C11.4, Cele\B0238.1, Cele\F15A8.6, Cele\T28C12.5, Cele\K11G9.3, Cele\C01B10.4, Cele\R173.3, Cele\W02B12.4, Cele\C01B10.10, Cele\ges-1, Cele\Y71H2AM.13, Cele\T07H6.1, Cele\T02B5.3, Cele\K11G9.1, Cele\F07C4.12, Cele\K11G9.2" "Xtro\LOC100494782, Xtro\cel, Xtro\ces3, Xtro\nlgn2, Xtro\ces2, Xtro\nlgn3, Xtro\nlgn4x" "Mmus\Ces1d, Mmus\Cel, Mmus\Ces2c, Mmus\Ces1e, Mmus\Ces2f, Mmus\Ces2g, Mmus\Nlgn1, Mmus\Ces1f, Mmus\Ces2a, Mmus\Ces3b, Mmus\Ces1b, Mmus\Ces4a, Mmus\Bche, Mmus\Ces3a, Mmus\Ces1h, Mmus\Ces1g, Mmus\Ces2h, Mmus\Ces2e, Mmus\Ces1c, Mmus\Ces5a, Mmus\Nlgn2, Mmus\Nlgn3, Mmus\Ces2b" "Hsap\CEL, Hsap\CES1, Hsap\CES4A, Hsap\CES5A, Hsap\BCHE, Hsap\NLGN2, Hsap\CES2, Hsap\NLGN1, Hsap\NLGN4Y, Hsap\CES3, Hsap\NLGN4X, Hsap\NLGN3" "stress response defective,mating defective,male,recessive" "oocyte,embryonic/larval fat body" FBgn0040486 BobB Brother of Bearded B http://flybase.org/reports/FBgn0040486 gene protein binding ; GO:0005515 | inferred from physical interaction with neur - - "Bob-B, Bob, BobB" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0052233 CG32233 - http://flybase.org/reports/FBgn0052233 protein_coding_gene - - - CG32233 - - 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0039092 CG16723 - http://flybase.org/reports/FBgn0039092 protein_coding_gene "transferase activity, transferring acyl groups other than amino-acyl groups ; GO:0016747 | inferred from electronic annotation with InterPro:IPR002656" - - CG16723 "IPR002656:Acyltransferase 3, IPR006621:Nose resistant-to-fluoxetine protein, N-terminal" CG16723 27-Aug-18 DroID_v2018_08 Drer\oacyl - "Cele\nrf-6, Cele\oac-9, Cele\oac-55, Cele\ndg-4, Cele\oac-5, Cele\oac-3, Cele\oac-31, Cele\oac-53, Cele\oac-46, Cele\oac-50, Cele\oac-39, Cele\rhy-1, Cele\oac-20, Cele\oac-32, Cele\oac-6, Cele\oac-14, Cele\oac-54, Cele\oac-7" Xtro\LOC101732251 Mmus\Oacyl - "partially lethal - majority die,some die during pupal stage" FBgn0260318 GSd317 - http://flybase.org/reports/FBgn0260318 gene - - - GSd317 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,neuroanatomy defective" "ventral nerve cord,intersegmental nerve,segmental nerve" FBgn0086302 polk polka dot http://flybase.org/reports/FBgn0086302 gene - dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype - polk - - 27-Aug-18 DroID_v2018_08 - - - - - - "neuroanatomy defective,lethal,recessive" dendrite | larval stage FBgn0050372 Asap "ArfGAP with SH3 domain, ankyrin repeat and PH domain" http://flybase.org/reports/FBgn0050372 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from electronic annotation with InterPro:IPR001164 phosphatidylinositol phosphate binding ; GO:1901981 | inferred from sequence or structural similarity with MGI:MGI:1342335 GTPase activator activity ; GO:0005096 | inferred from sequence model regulation of GTPase activity ; GO:0043087 | inferred from sequence model cytoplasm ; GO:0005737 | inferred from direct assay adherens junction ; GO:0005912 | colocalizes_with inferred from direct assay "CG2226, CG14758, CG30372, dAsap, Asap, Asap1, ASAP" "IPR001164:Arf GTPase activating protein, IPR001452:SH3 domain, IPR001849:Pleckstrin homology domain, IPR002110:Ankyrin repeat, IPR011993:PH domain-like, IPR027267:Arfaptin homology (AH) domain/BAR domain, IPR020683:Ankyrin repeat-containing domain" CG30372 27-Aug-18 DroID_v2018_08 "Drer\zgc:162872, Drer\acap3a, Drer\asap1a, Drer\acap3b, Drer\si:ch211-168b3.1, Drer\asap3, Drer\asap1b, Drer\appl1, Drer\asap2a, Drer\asap2b, Drer\appl2, Drer\unm_sa1614" "Scer\AGE1, Scer\AGE2, Scer\GTS1" - "Xtro\acap1, Xtro\asap1, Xtro\acap3, Xtro\appl1, Xtro\arap3, Xtro\appl2, Xtro\acap2, Xtro\asap2" "Mmus\Acap1, Mmus\Asap3, Mmus\Appl2, Mmus\9030624G23Rik, Mmus\Appl1, Mmus\Acap3, Mmus\Asap2, Mmus\Acap2, Mmus\Asap1" "Hsap\ASAP3, Hsap\ACAP2, Hsap\APPL2, Hsap\APPL1, Hsap\ASAP1, Hsap\ACAP1, Hsap\ACAP3, Hsap\ASAP2" viable FBgn0038838 TotB Turandot B http://flybase.org/reports/FBgn0038838 protein_coding_gene - cellular response to UV ; GO:0034644 | inferred from expression pattern response to bacterium ; GO:0009617 | inferred from expression pattern response to heat ; GO:0009408 | inferred from direct assay cellular response to heat ; GO:0034605 | inferred from expression pattern response to UV ; GO:0009411 | inferred from direct assay extracellular space ; GO:0005615 | inferred from sequence or structural similarity with TotA extracellular region ; GO:0005576 | inferred from sequence model "tot, CG5609, BcDNA:LP06769, TotB, Tot B" IPR010825:Stress-inducible humoral factor Turandot CG5609 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264721 lncRNA:CR43989 - http://flybase.org/reports/FBgn0264721 non_protein_coding_gene - - - CR43989 - CR43989 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0010076 Ni-K Nicked of Klein http://flybase.org/reports/FBgn0010076 - gene - - - "Ni-K, Ni" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0084807 1.1.3 1.1.3 http://flybase.org/reports/FBgn0084807 gene - - - 1.1.3 - - 27-Aug-18 DroID_v2018_08 - - - - - - eye color defective pigment cell FBgn0003121 pod podgy http://flybase.org/reports/FBgn0003121 - gene - - - pod - - 27-Aug-18 DroID_v2018_08 - - - - - - mitotic cell cycle defective FBgn0062537 anon-3929 anon-3929 http://flybase.org/reports/FBgn0062537 gene - - - "3929, anon-3929" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0052986 CG32986 - http://flybase.org/reports/FBgn0052986 protein_coding_gene - - - "CG15866, CG32986" - CG32986 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC02509 K 0.532379035 -0.119388262 -0.003069778 0.695146429 2.088412578 0.367085636 FBgn0069150 mcl(3)Z3401 mcl(3)Z3401 http://flybase.org/reports/FBgn0069150 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z3401 - - 27-Aug-18 DroID_v2018_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0030899 Hesr HES-related http://flybase.org/reports/FBgn0030899 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR003650 protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011598 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR003650" - "CG5927, Hesr, Her, bHLHc21" "IPR003650:Orange domain, IPR011598:Myc-type, basic helix-loop-helix (bHLH) domain" CG5927 27-Aug-18 DroID_v2018_08 "Drer\hey1, Drer\hes2.1, Drer\hey2, Drer\her12, Drer\her4.3, Drer\hes6, Drer\her8.2, Drer\bhlhe41, Drer\her4.2, Drer\her15.1, Drer\her15.2, Drer\LOC100149863, Drer\her4.4, Drer\hes2.2, Drer\her2, Drer\her7, Drer\her6, Drer\her5, Drer\her9, Drer\her11, Drer\helt, Drer\her1, Drer\her8a, Drer\bhlhe40, Drer\her13, Drer\heyl, Drer\her3" Scer\PHO4 "Cele\hlh-25, Cele\hlh-27, Cele\lin-22" "Xtro\hey1, Xtro\hes2, Xtro\hes6.1, Xtro\bhlhe40, Xtro\hes1, Xtro\hes4, Xtro\hey2, Xtro\hes7.1, Xtro\hes7.2, Xtro\bhlhe41" "Mmus\Bhlhe41, Mmus\Hes5, Mmus\Hes2, Mmus\Hey2, Mmus\Heyl, Mmus\Hes6, Mmus\Bhlhe40, Mmus\Helt, Mmus\Hes7, Mmus\Hey1, Mmus\Hes3, Mmus\Hes1" "Hsap\HES4, Hsap\BHLHE41, Hsap\HES5, Hsap\HES1, Hsap\HES3, Hsap\HEY1, Hsap\HES6, Hsap\HEYL, Hsap\BHLHE40, Hsap\HELT, Hsap\HEY2, Hsap\HES7, Hsap\HES2" viable FBgn0033770 wuc Wake-up-call http://flybase.org/reports/FBgn0033770 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with aly inferred from physical interaction with comr inferred from physical interaction with topi male meiosis ; GO:0007140 | inferred from direct assay negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype DRM complex ; GO:0070176 | inferred from electronic annotation with InterPro:IPR018737 nuclear chromatin ; GO:0000790 | inferred from direct assay "147114_at, BcDNA:AT27450, wuc, CG12442" IPR018737:Protein LIN52 CG12442 27-Aug-18 DroID_v2018_08 Drer\lin52 - Cele\lin-52 Xtro\lin52 Mmus\Lin52 Hsap\LIN52 viable FBgn0036567 CG13074 - http://flybase.org/reports/FBgn0036567 protein_coding_gene - sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - CG13074 "IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR007110:Immunoglobulin-like domain" CG13074 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0039582 Or98b Odorant receptor 98b http://flybase.org/reports/FBgn0039582 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with Or43b olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 dendrite membrane ; GO:0032590 | inferred from sequence or structural similarity with Or22a integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000474402 "98b, CG1867, DOR121, 98C.1, Or98b, Or98bP, or98b" "IPR004117:Olfactory receptor, insect" CG1867 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0033817 GstE14 Glutathione S transferase E14 http://flybase.org/reports/FBgn0033817 protein_coding_gene glutathione transferase activity ; GO:0004364 | inferred from direct assay ecdysteroid biosynthetic process ; GO:0045456 | inferred from mutant phenotype glutathione metabolic process ; GO:0006749 | inferred from direct assay cholesterol homeostasis ; GO:0042632 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with RGD:70952 "CG4688, GstE14, gste14, GSTE14, nobo" "IPR004045:Glutathione S-transferase, N-terminal, IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold, IPR004046:Glutathione S-transferase, C-terminal" CG4688 27-Aug-18 DroID_v2018_08 "Drer\gstr, Drer\gstt1b, Drer\gstt1a, Drer\eef1e1, Drer\vars, Drer\gstt2, Drer\mars, Drer\eef1g" "Scer\CAM1, Scer\YGR201C, Scer\TEF4, Scer\GTT2, Scer\URE2, Scer\GTT1" "Cele\gst-44, Cele\gst-34, Cele\C02D5.4, Cele\gst-35, Cele\gsto-3, Cele\gsto-2" "Xtro\eef1e1, Xtro\gstt1, Xtro\gsto1, Xtro\eef1g" "Mmus\Gstt4, Mmus\Eef1g, Mmus\Mars, Mmus\Gsto1, Mmus\Eef1e1, Mmus\Gstt2, Mmus\Gstt1, Mmus\Vars, Mmus\Gstt3" "Hsap\EEF1E1, Hsap\GSTT2, Hsap\GSTT2B, Hsap\VARS, Hsap\GSTO2, Hsap\MARS, Hsap\EEF1G, Hsap\GSTO1, Hsap\GSTT1" viable FBgn0043010 Fsn F-box synaptic protein http://flybase.org/reports/FBgn0043010 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model protein binding ; GO:0005515 | inferred from physical interaction with hiw inferred from physical interaction with Rae1 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9NB71 neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype positive regulation of protein catabolic process ; GO:0045732 | inferred from mutant phenotype negative regulation of gene expression ; GO:0010629 | inferred from mutant phenotype SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model cell cortex ; GO:0005938 | inferred from direct assay pole plasm ; GO:0045495 | inferred from direct assay SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay neuromuscular junction ; GO:0031594 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "BEST:GH20696, DFsn, Wals, Fsn, CG4643, FBXO2, dFsn, fsn" "IPR001810:F-box domain, IPR001870:B30.2/SPRY domain, IPR003877:SPRY domain, IPR013320:Concanavalin A-like lectin/glucanase domain" CG4643 27-Aug-18 DroID_v2018_08 "Drer\fbxo45, Drer\spsb3b, Drer\spsb1, Drer\spsb4b, Drer\spsb4a" - "Cele\spsb-1, Cele\fsn-1, Cele\spsb-2" "Xtro\fbxo45, Xtro\spsb1" "Mmus\Spsb2, Mmus\Spsb4, Mmus\Spsb1, Mmus\Fbxo45" "Hsap\SPSB1, Hsap\SPSB2, Hsap\FBXO45, Hsap\SPSB4" "partially lethal - majority live,maternal effect,viable,male sterile,neuroanatomy defective,neurophysiology defective,body color defective" "type I bouton,supernumerary,embryonic/larval neuromuscular junction,pole cell,maternal effect,mesothoracic tergum" FBgn0019674 mor(1)5 mortality gene (1)5 http://flybase.org/reports/FBgn0019674 - gene - - - mor(1)5 - - 27-Aug-18 DroID_v2018_08 - - - - - - short lived FBgn0023137 WppF White prepupal locus F http://flybase.org/reports/FBgn0023137 - gene - - - "8, 15, WppF" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0029820 CG16721 - http://flybase.org/reports/FBgn0029820 protein_coding_gene molecular_function ; GO:0003674 | no biological data available cAMP-mediated signaling ; GO:0019933 | inferred from sequence or structural similarity with SGD:S000002413 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000002413 CG16721 IPR008862:T-complex 11 CG16721 27-Aug-18 DroID_v2018_08 "Drer\tcp11l1, Drer\tcp11l2" Scer\SOK1 Cele\M05D6.2 "Xtro\tcp11l1, Xtro\tcp11l2" "Mmus\Tcp11x2, Mmus\Tcp11, Mmus\Tcp11l1, Mmus\Tcp11l2" "Hsap\TCP11L2, Hsap\TCP11X1, Hsap\TCP11X2, Hsap\TCP11, Hsap\TCP11L1" viable FBgn0061101 l(3)S008831b lethal (3) S008831b http://flybase.org/reports/FBgn0061101 gene - - - "0088/31, l(3)S008831b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0027263 l(1)G0223 lethal (1) G0223 http://flybase.org/reports/FBgn0027263 - gene - - - l(1)G0223 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0001071 Fs(3)Zer Female sterile (3) Zerind http://flybase.org/reports/FBgn0001071 - gene molecular_function ; GO:0003674 | no biological data available meiotic nuclear division ; GO:0007126 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "Zer, Fs(3)Zerind, Fs(3)Sz25, Fs(3)Zer" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,meiotic cell cycle defective" "female pronucleus | maternal effect,pronucleus | maternal effect" FBgn0011104 l(1)Q65 lethal (1) Q65 http://flybase.org/reports/FBgn0011104 FBgn0010210 gene - - - l(1)Q65 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0020243 ziti ziti http://flybase.org/reports/FBgn0020243 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available ziti - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0019637 Atu Another transcription unit http://flybase.org/reports/FBgn0019637 FBgn0011015 protein_coding_gene RNA polymerase II C-terminal domain phosphoserine binding ; GO:1990269 | inferred from biological aspect of ancestor with PANTHER:PTN000567381 histone modification ; GO:0016570 | inferred from electronic annotation with InterPro:IPR007149 positive regulation of transcription elongation from RNA polymerase II promoter ; GO:0032968 | inferred from biological aspect of ancestor with PANTHER:PTN000567381 regulation of hemocyte proliferation ; GO:0035206 | inferred from mutant phenotype Cdc73/Paf1 complex ; GO:0016593 | inferred from electronic annotation with InterPro:IPR007149 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000567381 "atu, l(3)s1938, CG1433, Atu" IPR007149:Leo1-like protein CG1433 27-Aug-18 DroID_v2018_08 Drer\leo1 Scer\LEO1 Cele\leo-1 Xtro\leo1 Mmus\Leo1 Hsap\LEO1 "lethal,recessive,viable,body color defective" mesothoracic tergum FBgn0030196 Psf3 Psf3 http://flybase.org/reports/FBgn0030196 protein_coding_gene 3'-5' DNA helicase activity ; GO:0043138 | contributes_to inferred from direct assay lateral inhibition ; GO:0046331 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype GINS complex ; GO:0000811 | inferred from direct assay "CG2222, Psf3" "IPR010492:GINS complex, subunit Psf3, IPR021151:GINS subunit, domain A" CG2222 27-Aug-18 DroID_v2018_08 Drer\gins3 Scer\PSF3 Cele\psf-3 Xtro\gins3 Mmus\Gins3 Hsap\GINS3 "lethal,neuroanatomy defective,viable,visible" "embryonic/larval neuroblast,ganglion mother cell,chaeta,trichogen cell" FBgn0264002 MsR2 Myosuppressin receptor 2 http://flybase.org/reports/FBgn0264002 protein_coding_gene myosuppressin receptor activity ; GO:0035013 | inferred from direct assay G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity neuropeptide receptor activity ; GO:0008188 | inferred from sequence model myosuppressin receptor activity ; GO:0035013 | inferred from physical interaction with Ms neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence model adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway ; GO:0007193 | inferred from direct assay larval locomotory behavior ; GO:0008345 | inferred from mutant phenotype G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity adult locomotory behavior ; GO:0008344 | inferred from mutant phenotype behavioral defense response ; GO:0002209 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity "DmsR-2, CG43745, CG13802, DmsR, CG13803, DMSR-2, anon-WO0170980.161, anon-WO0170980.160, Dm CG13803, MsR2, DMS-R2, MS-R" "IPR017452:GPCR, rhodopsin-like, 7TM, IPR019427:7TM GPCR, serpentine receptor class w (Srw), IPR000276:G protein-coupled receptor, rhodopsin-like" CG43745 27-Aug-18 DroID_v2018_08 "Drer\gper1, Drer\gpr142" - "Cele\K01A6.6, Cele\Y70C5A.4, Cele\srw-123, Cele\srw-107, Cele\C41G6.16, Cele\srw-35, Cele\srw-24, Cele\srw-44, Cele\srw-130, Cele\srw-31, Cele\srw-98, Cele\dmsr-11, Cele\srw-121, Cele\dmsr-4, Cele\srw-20, Cele\srw-32, Cele\T27C5.10, Cele\dmsr-13, Cele\srw-61, Cele\srw-72, Cele\C09F12.3, Cele\srw-87, Cele\dmsr-2, Cele\srw-134, Cele\srw-141, Cele\srw-10, Cele\srw-14, Cele\T02D1.4, Cele\srw-89, Cele\srw-67, Cele\srw-137, Cele\srw-115, Cele\dmsr-3, Cele\srw-2, Cele\srw-95, Cele\dmsr-15, Cele\dmsr-10, Cele\frpr-13, Cele\srw-60, Cele\dmsr-9, Cele\srw-66, Cele\srw-133, Cele\srw-76, Cele\srw-94, Cele\srw-63, Cele\srw-3, Cele\F38E1.6, Cele\srw-54, Cele\Y75B12B.10, Cele\srw-73, Cele\srw-101, Cele\srw-68, Cele\srw-55, Cele\srw-4, Cele\srw-9, Cele\dmsr-6, Cele\srw-99, Cele\dmsr-1, Cele\srw-33, Cele\srw-40, Cele\T26H8.4, Cele\F09C6.16, Cele\srw-100, Cele\egl-6, Cele\srw-62, Cele\srw-142, Cele\srw-82, Cele\srw-120, Cele\srw-36, Cele\srw-42, Cele\srw-53, Cele\srw-19, Cele\srw-39, Cele\srw-71, Cele\sprr-3, Cele\srw-97, Cele\srw-21, Cele\srw-6, Cele\srw-111, Cele\dmsr-8, Cele\srw-69, Cele\dmsr-14, Cele\srw-108, Cele\srw-90, Cele\dmsr-5, Cele\srw-88, Cele\srw-103, Cele\srw-34, Cele\srw-11, Cele\C47E8.3, Cele\srw-136, Cele\srw-41, Cele\srw-38, Cele\frpr-7, Cele\srw-23, Cele\dmsr-12, Cele\srw-12, Cele\srw-22, Cele\srw-17, Cele\srw-56, Cele\srw-8, Cele\srw-15, Cele\srw-122, Cele\srw-7, Cele\srw-143, Cele\srw-119, Cele\srw-85, Cele\srw-117, Cele\M03F8.7, Cele\srw-16, Cele\srw-26, Cele\srw-75, Cele\srw-1, Cele\srw-139, Cele\srw-29, Cele\srw-51, Cele\dmsr-7, Cele\srw-84, Cele\srw-129, Cele\srw-77, Cele\srw-140, Cele\F13H6.5, Cele\srw-124, Cele\dmsr-16, Cele\C25F9.13, Cele\srw-48, Cele\srw-118, Cele\srw-59, Cele\srw-83, Cele\srw-57, Cele\srw-145, Cele\srw-13, Cele\srw-138, Cele\T26H8.5, Cele\srw-127, Cele\srw-113, Cele\srw-43, Cele\srw-91, Cele\srw-109, Cele\srw-79, Cele\srw-102, Cele\srw-112, Cele\M01G12.6, Cele\srw-144, Cele\srw-30" - "Mmus\Gpr142, Mmus\Gpr139" "Hsap\GPR139, Hsap\GPR142" DRSC22440 E 0.526483414 0.355720274 1.580070182 0.124020341 0.811318223 -0.171148876 FBgn0067673 ninja\pol ninja element pol http://flybase.org/reports/FBgn0067673 transposable_element_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001878 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001878, InterPro:IPR012337" DNA integration ; GO:0015074 | inferred from electronic annotation with InterPro:IPR001584 - ninja\pol "IPR021109:Aspartic peptidase domain, IPR001584:Integrase, catalytic core, IPR008042:Retrotransposon, Pao, IPR012337:Ribonuclease H-like domain, IPR005312:Protein of unknown function DUF1759, IPR001878:Zinc finger, CCHC-type" - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002481 l(3)SG38 lethal (3) SG38 http://flybase.org/reports/FBgn0002481 - gene - - - "l(3)m45, l(3)SG38" - - 27-Aug-18 DroID_v2018_08 - - - - - - "mitotic cell cycle defective,lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" "imaginal disc,cell cycle" FBgn0051008 CG31008 - http://flybase.org/reports/FBgn0051008 protein_coding_gene sequence-specific DNA binding ; GO:0043565 | inferred from sequence or structural similarity with HGNC:21645 mitochondrion organization ; GO:0007005 | inferred from biological aspect of ancestor with PANTHER:PTN000338319 positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from sequence or structural similarity with HGNC:21645 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000338319 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000338319 mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with HGNC:21645 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:21645 "bs08f11.y1, BEST:GH26101, CG31008" IPR010625:CHCH CG31008 27-Aug-18 DroID_v2018_08 "Drer\chchd2, Drer\chchd10" Scer\MIX17 Cele\har-1 "Xtro\gpat3, Xtro\chchd10" "Mmus\Chchd2, Mmus\Chchd10" "Hsap\CHCHD10, Hsap\CHCHD2" viable FBgn0260593 2L2653 - http://flybase.org/reports/FBgn0260593 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L2653 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" "dorsal air sac primordium,somatic clone" FBgn0052285 tRNA:Lys-CTT-1-12 transfer RNA:Lysine-CTT 1-12 http://flybase.org/reports/FBgn0052285 tRNA_gene AAG codon-amino acid adaptor activity ; GO:0033444 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033444 cytosol ; GO:0005829 | inferred by curator from GO:0033444 "CR32285, AE002584.trna17-LysCTT, tRNA[Lys][[2]], tRNA:lys2:63B, tRNA:K2:63B, tRNA:K2, tRNA:K:CTT:AE002584-a, chr3L.trna17-LysCTT, tRNA-Lys-CTT-1-12, tRNA:Lys-CTT-1-12, tRNA:CR32285, AAG" - CR32285 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260228 CG42502 - http://flybase.org/reports/FBgn0260228 protein_coding_gene - - - "CG42502, Dromel_CG10570_FBtr0081122_uORF" - CG42502 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263952 BG00907 - http://flybase.org/reports/FBgn0263952 gene - - - BG00907 - - 27-Aug-18 DroID_v2018_08 - - - - - - "long lived,male limited,starvation stress response defective,temperature response defective,gravitaxis defective" FBgn0004429 LysP Lysozyme P http://flybase.org/reports/FBgn0004429 FBgn0002575 protein_coding_gene lysozyme activity ; GO:0003796 | inferred from electronic annotation with InterPro:IPR000974 lysozyme activity ; GO:0003796 | inferred from sequence or structural similarity - - "LysP, lysP, CG9116" "IPR000974:Glycoside hydrolase, family 22, lysozyme, IPR001916:Glycoside hydrolase, family 22, IPR019799:Glycoside hydrolase, family 22, conserved site, IPR023346:Lysozyme-like domain" CG9116 27-Aug-18 DroID_v2018_08 "Drer\LOC100536671, Drer\lyz, Drer\LOC100334363" - - Xtro\MGC89221 "Mmus\Lalba, Mmus\Spaca5, Mmus\Spaca7, Mmus\Spaca3, Mmus\9530003J23Rik, Mmus\Spaca1, Mmus\Spaca4, Mmus\Lyz1, Mmus\Lyz2, Mmus\Lyzl6, Mmus\Lyzl4, Mmus\1700016D06Rik, Mmus\Lyzl1" "Hsap\LALBA, Hsap\SPACA4, Hsap\SPACA7, Hsap\LYZL6, Hsap\SPACA3, Hsap\LYZL4, Hsap\LYZL1, Hsap\SPACA1, Hsap\LYZ, Hsap\SPACA5, Hsap\SPACA5B, Hsap\LYZL2" adult stage adult salivary gland

viable FBgn0085329 CG34300 - http://flybase.org/reports/FBgn0085329 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34300 - CG34300 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065638 l(2)SH0764 lethal (2) SH0764 http://flybase.org/reports/FBgn0065638 gene - - - "l(2)SH0764, l(2)SH2 0764" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0021998 l(2)k09328 lethal (2) k09328 http://flybase.org/reports/FBgn0021998 - gene - - - l(2)k09328 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0021883 l(2)k13412 lethal (2) k13412 http://flybase.org/reports/FBgn0021883 - gene - - - l(2)k13412 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0038437 Sdhaf3 Succinate dehydrogenase assembly factor 3 http://flybase.org/reports/FBgn0038437 protein_coding_gene - musculoskeletal movement ; GO:0050881 | inferred from mutant phenotype mitochondrial respiratory chain complex II assembly ; GO:0034553 | inferred from biological aspect of ancestor with PANTHER:PTN000320077 regulation of gluconeogenesis ; GO:0006111 | inferred from biological aspect of ancestor with PANTHER:PTN000320077 succinate metabolic process ; GO:0006105 | inferred from mutant phenotype response to oxidative stress ; GO:0006979 | inferred from mutant phenotype response to hyperoxia ; GO:0055093 | inferred from mutant phenotype mitochondrial intermembrane space ; GO:0005758 | inferred from biological aspect of ancestor with PANTHER:PTN000320077 "BcDNA:RE23580, Sdhaf3, CG14898, sdh7, dSdhaf3, Sdh7" IPR008381:ACN9 CG14898 27-Aug-18 DroID_v2018_08 Drer\sdhaf3 Scer\SDH7 Cele\F25H9.7 Xtro\sdhaf3 Mmus\Sdhaf3 Hsap\SDHAF3 viable DRSC15020 K -0.130708578 0.83602864 0.429028768 0.487062194 0.358231109 4.842556114 FBgn0051887 CG31887 - http://flybase.org/reports/FBgn0051887 protein_coding_gene - - - CG31887 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0024525 l(3)j5E7 lethal (3) j5E7 http://flybase.org/reports/FBgn0024525 - gene - - - l(3)j5E7 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0063909 N::Mmus\Notch1 Notch1 http://flybase.org/reports/FBgn0063909 engineered_fusion_gene - - - N::Mmus\Notch1 - - 27-Aug-18 DroID_v2018_08 - - - - - - neuroanatomy defective "dorsal abdominal cluster,presumptive embryonic/larval peripheral nervous system,S2 cell-line" FBgn0040735 CG16836 - http://flybase.org/reports/FBgn0040735 protein_coding_gene - - - CG16836 IPR013172:Immune-induced protein Dim CG16836 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0082376 E(GMR-wIR)A28 Enhancer(GMR-wIR)A28 http://flybase.org/reports/FBgn0082376 gene - - - E(GMR-wIR)A28 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004781 Ccp84Ac Ccp84Ac http://flybase.org/reports/FBgn0004781 - protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "cc6, CG1327, BG:DS00004.3, Ccp84Ac, Ccp, DmelCcp84Ac" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG1327 27-Aug-18 DroID_v2018_08 - - Cele\fbxb-38 - - - "visible,partially lethal - majority die,some die during pupal stage" trichogen cell DRSC12588 K 0.444798667 0.296208733 -0.002042957 0.016943411 1.099519121 -1.759340902 FBgn0036890 CG9368 - http://flybase.org/reports/FBgn0036890 protein_coding_gene - - - "BcDNA:RH51268, CG9368" - CG9368 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC11067 I -0.326665271 1.646061633 -0.168937514 0.147620142 -0.11164128 -0.566697809 FBgn0026168 spnl space-needle http://flybase.org/reports/FBgn0026168 - gene - - - spnl - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0028406 Drep4 DNA fragmentation factor-related protein 4 http://flybase.org/reports/FBgn0028406 protein_coding_gene deoxyribonuclease activity ; GO:0004536 | inferred from biological aspect of ancestor with PANTHER:PTN000990874 apoptotic DNA fragmentation ; GO:0006309 | inferred from electronic annotation with InterPro:IPR015311 apoptotic DNA fragmentation ; GO:0006309 | traceable author statement cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR015311 nuclear chromatin ; GO:0000790 | inferred from biological aspect of ancestor with PANTHER:PTN000990874 "dCAD, CG9414, CAD, drep4, DREP-4, Rep4, Drep4, Drep-4" "IPR003508:CIDE-N domain, IPR015311:Apoptosis, DNA fragmentation factor 40kDa" CG9414 27-Aug-18 DroID_v2018_08 "Drer\impa2, Drer\dffb" "Scer\INM1, Scer\INM2" - "Xtro\dffb, Xtro\impa1" "Mmus\Impa1, Mmus\Dffb" "Hsap\IMPA1, Hsap\DFFB" viable FBgn0267888 CR46176 - http://flybase.org/reports/FBgn0267888 pseudogene_attribute - - - "CR46176, CG12717-related" - CR46176 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0069998 BG01656 BG01656 http://flybase.org/reports/FBgn0069998 gene - - - BG01656 - - 27-Aug-18 DroID_v2018_08 - - - - - - stress response defective FBgn0003922 snRNA:U2:38ABa small nuclear RNA U2 at 38ABa http://flybase.org/reports/FBgn0003922 FBgn0003919 snRNA_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity" U2 snRNP ; GO:0005686 | inferred from sequence or structural similarity Cajal body ; GO:0015030 | inferred from direct assay "U2:38ABa, U2, dU2, U2 snRNA, U2-38ABa, snRNA[[1]], K6, Dm U2-141A, D.U2-3, U2-141A, 141A, snRNA-U2-141A, snRNA:U2:39B, snRNA:U2, snRNA2, snRNA1, U2snRNA39B, CR32882, U2snRNA, snRNA:U2:38ABa, U2:39AB, 38A U2" - CR32882 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260346 GSd497 - http://flybase.org/reports/FBgn0260346 gene - - - GSd497 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,neuroanatomy defective" "ventral nerve cord,longitudinal connective,intersegmental nerve" FBgn0040759 CG13177 - http://flybase.org/reports/FBgn0040759 protein_coding_gene - - - CG13177 - CG13177 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038359 CG5614 - http://flybase.org/reports/FBgn0038359 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG5614 IPR006594:LIS1 homology motif CG5614 27-Aug-18 DroID_v2018_08 Drer\fopnl - - - Mmus\Fopnl Hsap\FOPNL "viable,fertile" FBgn0069240 fz::smo fz::smo http://flybase.org/reports/FBgn0069240 engineered_fusion_gene - - - fz::smo - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing,costal cell,wing vein,ectopic,1st posterior cell" FBgn0014355 lup-2 loop unfolding protein-2 http://flybase.org/reports/FBgn0014355 - gene - sperm axoneme assembly ; GO:0007288 | inferred from mutant phenotype - "ms(3)HB267, lup-2" - - 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,recessive" "Y chromosome loop,spermatid axoneme,axonemal dynein complex,axonemal microtubule | ectopic,axonemal microtubule | supernumerary" FBgn0038662 Mpc1 Mitochondrial pyruvate carrier http://flybase.org/reports/FBgn0038662 protein_coding_gene pyruvate transmembrane transporter activity ; GO:0050833 | inferred from sequence or structural similarity with SGD:S000003048 pyruvate transmembrane transporter activity ; GO:0050833 | inferred from biological aspect of ancestor with PANTHER:PTN000365848 mitochondrial pyruvate transport ; GO:0006850 | inferred from sequence or structural similarity with SGD:S000003048 mitochondrial pyruvate transmembrane transport ; GO:1902361 | inferred from biological aspect of ancestor with PANTHER:PTN000365848 pyruvate metabolic process ; GO:0006090 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from direct assay integral component of mitochondrial inner membrane ; GO:0031305 | inferred from sequence or structural similarity with SGD:S000003048 integral component of mitochondrial inner membrane ; GO:0031305 | inferred from biological aspect of ancestor with PANTHER:PTN000365848 "CG14290, Mpc1, dMPC1" IPR005336:Mitochondrial pyruvate carrier CG14290 27-Aug-18 DroID_v2018_08 Drer\mpc1 Scer\MPC1 Cele\R07E5.13 Xtro\mpc1 Mmus\Mpc1 "Hsap\MPC1, Hsap\MPC1L" "viable,fertile,neuroanatomy defective,lethal,nutrition conditional" neurite | pharate adult stage FBgn0044071 E(rst)K137 E(rst)K137 http://flybase.org/reports/FBgn0044071 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "K137, E(rst)K137" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259453 EP-J63.2 - http://flybase.org/reports/FBgn0259453 gene - - - EP-J63.2 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing vein,wing margin" FBgn0265859 lncRNA:CR44648 - http://flybase.org/reports/FBgn0265859 non_protein_coding_gene - - - CR44648 - CR44648 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034362 CG5323 - http://flybase.org/reports/FBgn0034362 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG5323 "IPR008560:Protein of unknown function DUF842, eukaryotic" CG5323 27-Aug-18 DroID_v2018_08 Drer\fam136a - Cele\ZK637.2 Xtro\fam136a Mmus\Fam136a Hsap\FAM136A viable FBgn0069426 JJF015 JJF015 http://flybase.org/reports/FBgn0069426 gene - - - JJF015 - - 27-Aug-18 DroID_v2018_08 - - - - - - stress response defective FBgn0025763 l(3)89Em lethal (3) 89Em http://flybase.org/reports/FBgn0025763 - gene - - - "l(3)M96, l(3)89Em" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0035797 CG14837 - http://flybase.org/reports/FBgn0035797 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14837 - CG14837 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0016080 xmas-1 xmas-1 http://flybase.org/reports/FBgn0016080 "FBgn0030822, FBgn0052561" protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG8919, xmas, l(1)15Ea, ms3, ms(1)3, m(1)3, CG32561, xmas-1" - CG32561 27-Aug-18 DroID_v2018_08 "Drer\mcm3ap, Drer\si:zfos-452g4.1" Scer\SAC3 - Xtro\mcm3ap "Mmus\Mcm3ap, Mmus\Sac3d1" "Hsap\MCM3AP, Hsap\SAC3D1" "meiotic cell cycle defective,male sterile,viable" FBgn0082988 snoRNA:Psi28S-2442b snoRNA:Psi28S-2442b http://flybase.org/reports/FBgn0082988 snoRNA_gene - - - "snoRNA:Psi28S-2442b, psi28s-2442b, CR34612, chr3R:1424176..1424319" - CR34612 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0003697 thic thickened aristae http://flybase.org/reports/FBgn0003697 - gene molecular_function ; GO:0003674 | no biological data available flight behavior ; GO:0007629 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available thic - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,heat sensitive,eye color defective" "arista,sex comb,eye" FBgn0032636 CG5043 - http://flybase.org/reports/FBgn0032636 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG5043 - CG5043 27-Aug-18 DroID_v2018_08 - - Cele\ceh-44 - - - FBgn0033207 CG12826 - http://flybase.org/reports/FBgn0033207 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12826 - CG12826 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032194 CG4901 - http://flybase.org/reports/FBgn0032194 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002464, InterPro:IPR011545 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR002464, InterPro:IPR011545 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN000433338 helicase activity ; GO:0004386 | inferred from sequence or structural similarity" neurogenesis ; GO:0022008 | inferred from mutant phenotype RNA processing ; GO:0006396 | inferred from biological aspect of ancestor with PANTHER:PTN000433338 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000433338 nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN001053657 "cg4901, CG4901" "IPR001650:Helicase, C-terminal, IPR002464:DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site, IPR007502:Helicase-associated domain, IPR011709:Domain of unknown function DUF1605, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR011545:DEAD/DEAH box helicase domain" CG4901 27-Aug-18 DroID_v2018_08 "Drer\dhx40, Drer\dhx33, Drer\dhx34, Drer\dhx8, Drer\dhx15, Drer\dhx16" "Scer\DHR2, Scer\PRP22" "Cele\mog-4, Cele\mog-5, Cele\let-355, Cele\ddx-15, Cele\mog-1" "Xtro\dhx38, Xtro\dhx40, Xtro\dhx33, Xtro\dhx8, Xtro\dhx16, Xtro\ythdc2, Xtro\dhx15, Xtro\dhx34" "Mmus\Dhx15, Mmus\Dhx34, Mmus\Dhx16, Mmus\Dhx38, Mmus\Dhx33, Mmus\Ythdc2, Mmus\Dhx40, Mmus\Dhx8" "Hsap\DHX8, Hsap\DHX33, Hsap\YTHDC2, Hsap\DHX40, Hsap\DHX15, Hsap\DHX34, Hsap\DHX16, Hsap\DHX38" "lethal,neuroanatomy defective,viable,visible" "ganglion mother cell,trichogen cell,mesothoracic tergum" FBgn0040349 CG3699 - http://flybase.org/reports/FBgn0040349 protein_coding_gene "2,4-dienoyl-CoA reductase (NADPH) activity ; GO:0008670 | inferred from sequence or structural similarity with HGNC:2754" fatty acid beta-oxidation ; GO:0006635 | non-traceable author statement - "CT12411, EG:BACR7A4.14, CG3699" "IPR002347:Short-chain dehydrogenase/reductase SDR, IPR016040:NAD(P)-binding domain, IPR020904:Short-chain dehydrogenase/reductase, conserved site" CG3699 27-Aug-18 DroID_v2018_08 "Drer\pecr, Drer\dhrs7, Drer\decr1, Drer\decr2, Drer\elovl8a, Drer\zgc:101858, Drer\elovl7a, Drer\elovl4a, Drer\elovl4b, Drer\hsdl2, Drer\elovl1b, Drer\hsd17b14, Drer\hsd17b8, Drer\elovl1a, Drer\cbr4, Drer\bdh2, Drer\elovl7b, Drer\dhrs1, Drer\zgc:113054, Drer\elovl8b, Drer\elovl2, Drer\elovl5" "Scer\OAR1, Scer\IRC24, Scer\YIR035C, Scer\SPS19" "Cele\F12E12.11, Cele\T01G6.1, Cele\F28H7.2, Cele\decr-1.2, Cele\R05D8.9, Cele\F02C12.2, Cele\dhs-15, Cele\C06E4.3, Cele\C01G12.5, Cele\Y47G6A.22, Cele\R05D8.7, Cele\C06E4.6, Cele\decr-1.3, Cele\W03F9.9, Cele\D1054.8, Cele\C06B8.3, Cele\Y47G6A.21, Cele\F26D2.15, Cele\dhs-11, Cele\F25D1.5, Cele\ZK829.1, Cele\T01G6.10, Cele\dhs-25, Cele\F12E12.12, Cele\dhs-14" "Xtro\elovl7, Xtro\dhrs4, Xtro\cbr4, Xtro\hsdl2, Xtro\MGC147226, Xtro\elovl2, Xtro\MGC79752, Xtro\elovl5, Xtro\pecr, Xtro\decr1, Xtro\decr2, Xtro\elovl1, Xtro\hsd17b8, Xtro\hsd17b14, Xtro\dhrs7" "Mmus\Dhrs1, Mmus\Dhrs2, Mmus\Hsdl2, Mmus\Pecr, Mmus\H2-Ke6, Mmus\Elovl4, Mmus\Decr2, Mmus\Elovl2, Mmus\Dhrs4, Mmus\Decr1, Mmus\Dhrs7, Mmus\Bdh2, Mmus\Elovl7, Mmus\Elovl5, Mmus\Hsd17b14, Mmus\Cbr4" "Hsap\HSD17B8, Hsap\DHRS2, Hsap\DHRS4, Hsap\ELOVL4, Hsap\DECR2, Hsap\DHRS4L2, Hsap\ELOVL5, Hsap\DHRS1, Hsap\DHRS7, Hsap\ELOVL7, Hsap\DECR1, Hsap\HSDL2, Hsap\NME4, Hsap\ELOVL1, Hsap\CBR4, Hsap\ELOVL2, Hsap\BDH2, Hsap\HSD17B14, Hsap\PECR" viable FBgn0029762 NAAT1 Nutrient Amino Acid Transporter 1 http://flybase.org/reports/FBgn0029762 protein_coding_gene neurotransmitter:sodium symporter activity ; GO:0005328 | inferred from electronic annotation with InterPro:IPR000175 neutral amino acid transmembrane transporter activity ; GO:0015175 | inferred from direct assay cation:amino acid symporter activity ; GO:0005416 | inferred from sequence model L-amino acid transmembrane transporter activity ; GO:0015179 | inferred from direct assay neurotransmitter transporter activity ; GO:0005326 | inferred from sequence or structural similarity with DAT sodium:amino acid symporter activity ; GO:0005283 | inferred from mutant phenotype D-amino acid transmembrane transporter activity ; GO:0042943 | inferred from direct assay neutral amino acid transport ; GO:0015804 | inferred from direct assay neurotransmitter transport ; GO:0006836 | inferred from sequence or structural similarity with DAT D-amino acid transport ; GO:0042940 | inferred from direct assay L-amino acid transport ; GO:0015807 | inferred from direct assay sodium ion transport ; GO:0006814 | inferred from mutant phenotype amino acid transmembrane import ; GO:0044745 | inferred from sequence model integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000177662 integral component of plasma membrane ; GO:0005887 | inferred by curator from GO:0005283 integral component of membrane ; GO:0016021 | inferred from sequence model "anon-WO0149848.3, CG3252, NAAT1, DmNAT1, dmNAT1" IPR000175:Sodium:neurotransmitter symporter CG3252 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-117c9.5, Drer\slc6a9, Drer\slc6a13, Drer\slc6a13l, Drer\slc6a4b, Drer\si:ch211-132b12.1, Drer\si:ch211-132b12.6, Drer\slc6a2, Drer\slc6a4a, Drer\zgc:174946, Drer\slc6a8, Drer\slc6a6b, Drer\slc6a16b, Drer\slc6a13, Drer\slc6a16a, Drer\slc6a1l, Drer\slc6a11a, Drer\si:ch211-132b12.2, Drer\slc6a5, Drer\slc6a15, Drer\zgc:158225, Drer\slc6a19b, Drer\slc6a1a, Drer\slc6a19a.1, Drer\slc6a14, Drer\slc6a17, Drer\slc6a18, Drer\si:ch211-132b12.3, Drer\slc6a6a, Drer\slc6a1b" - "Cele\snf-5, Cele\mod-5, Cele\snf-6, Cele\dat-1, Cele\snf-7, Cele\snf-11, Cele\snf-2, Cele\snf-9, Cele\snf-12, Cele\snf-3" "Xtro\slc6a14.2, Xtro\slc6a6, Xtro\slc6a4, Xtro\slc6a17, Xtro\slc6a9, Xtro\slc6a12, Xtro\slc6a8, Xtro\slc6a16, Xtro\slc6a1, Xtro\slc6a19, Xtro\LOC100127682, Xtro\slc6a2, Xtro\slc6a5, Xtro\slc6a3, Xtro\slc6a13, Xtro\slc6a7, Xtro\slc6a15" "Mmus\Slc6a19, Mmus\Slc6a15, Mmus\Slc6a5, Mmus\Slc6a11, Mmus\Slc6a2, Mmus\Slc6a12, Mmus\Slc6a20a, Mmus\Slc6a3, Mmus\Slc6a18, Mmus\Slc6a6, Mmus\Slc6a7, Mmus\Slc6a14, Mmus\Slc6a8, Mmus\Slc6a4, Mmus\Slc6a9, Mmus\Slc6a13, Mmus\Slc6a1, Mmus\Slc6a17, Mmus\Slc6a20b" "Hsap\SLC6A1, Hsap\SLC6A2, Hsap\SLC6A9, Hsap\SLC6A17, Hsap\SLC6A20, Hsap\SLC6A11, Hsap\SLC6A19, Hsap\SLC6A15, Hsap\SLC6A18, Hsap\SLC6A6, Hsap\SLC6A4, Hsap\SLC6A8, Hsap\SLC6A5, Hsap\SLC6A14, Hsap\SLC6A12, Hsap\SLC6A3, Hsap\SLC6A13" viable FBgn0264998 lncRNA:CR44149 - http://flybase.org/reports/FBgn0264998 non_protein_coding_gene - - - "lincRNA.91, CR44149" - CR44149 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0043872 nompE no mechanoreceptor potential E http://flybase.org/reports/FBgn0043872 gene - sensory perception of sound ; GO:0007605 | inferred from mutant phenotype - nompE - - 27-Aug-18 DroID_v2018_08 - - - - - - "auditory perception defective,recessive,uncoordinated,neurophysiology defective,locomotor behavior defective,behavior defective" "wing,leg,macrochaeta,adult antennal nerve" FBgn0042167 CG18847 - http://flybase.org/reports/FBgn0042167 protein_coding_gene - - - CG18847 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038876 CG5919 - http://flybase.org/reports/FBgn0038876 protein_coding_gene "hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR000086, InterPro:IPR015797 isopentenyl-diphosphate delta-isomerase activity ; GO:0004452 | inferred from sequence or structural similarity with HGNC:5387 isopentenyl-diphosphate delta-isomerase activity ; GO:0004452 | inferred from biological aspect of ancestor with PANTHER:PTN000094419" isoprenoid biosynthetic process ; GO:0008299 | inferred from sequence or structural similarity with HGNC:5387 isopentenyl diphosphate biosynthetic process ; GO:0009240 | inferred from biological aspect of ancestor with PANTHER:PTN000094419 peroxisome ; GO:0005777 | inferred from sequence or structural similarity with HGNC:5387 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000094419 "CG5919, IPPI" "IPR000086:NUDIX hydrolase domain, IPR011876:Isopentenyl-diphosphate delta-isomerase, type 1, IPR015797:NUDIX hydrolase domain-like" CG5919 27-Aug-18 DroID_v2018_08 Drer\idi1 Scer\IDI1 Cele\idi-1 Xtro\idi1 "Mmus\Idi1, Mmus\Gm38481, Mmus\Idi2" "Hsap\IDI2, Hsap\IDI1" "viable,visible" tormogen cell FBgn0026874 CG13358 - http://flybase.org/reports/FBgn0026874 - protein_coding_gene - - - "CG13358, EG:34F3.10" - CG13358 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0052857 CG32857 - http://flybase.org/reports/FBgn0052857 protein_coding_gene iron-sulfur cluster binding ; GO:0051536 | inferred from electronic annotation with InterPro:IPR001075 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001075 molecular_function ; GO:0003674 | no biological data available "iron-sulfur cluster assembly ; GO:0016226 | inferred from electronic annotation with InterPro:IPR001075, InterPro:IPR017065 biological_process ; GO:0008150 | no biological data available" cellular_component ; GO:0005575 | no biological data available CG32857 "IPR000629:ATP-dependent RNA helicase DEAD-box, conserved site, IPR014824:Scaffold protein Nfu/NifU, N-terminal, IPR001075:NIF system FeS cluster assembly, NifU, C-terminal, IPR017065:NFU1 iron-sulfur cluster scaffold homologue" CG32857 27-Aug-18 DroID_v2018_08 "Drer\zgc:110319, Drer\nfu1" Scer\NFU1 Cele\lpd-8 Xtro\nfu1 Mmus\Nfu1 Hsap\NFU1 FBgn0085512 RYa RYamide http://flybase.org/reports/FBgn0085512 protein_coding_gene receptor agonist activity ; GO:0048018 | inferred from physical interaction with RYa-R cell surface receptor signaling pathway ; GO:0007166 | inferred from direct assay negative regulation of feeding behavior ; GO:2000252 | inferred from direct assay "extracellular space ; GO:0005615 | inferred by curator from GO:0007166,GO:0048018 extracellular region ; GO:0005576 | inferred by curator from GO:0007166,GO:0048018" "CG40733, dRYamide, RYa, RYamide" - CG40733 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0025824 HelIII HelIII http://flybase.org/reports/FBgn0025824 - gene helicase activity ; GO:0004386 | inferred from direct assay - - "DHEL III, HelIII" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000270 ccd central complex deranged http://flybase.org/reports/FBgn0000270 - gene - - - ccd - - 27-Aug-18 DroID_v2018_08 - - - - - - "learning defective,recessive,memory defective,locomotor behavior defective" ellipsoid body FBgn0000939 fs(2)A9 female sterile (2) A9 http://flybase.org/reports/FBgn0000939 - gene - - - fs(2)A9 - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive" "female reproductive system,egg,chorion,nucleus | pre-blastoderm stage" FBgn0005388 fs(1)A457 female sterile (1) A457 http://flybase.org/reports/FBgn0005388 "FBgn0000757, FBgn0000772" gene - - - "fs(1)457, fs(1)M22, fs(1)A457" - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive,lethal,non-rescuable maternal effect,maternal effect,mitotic cell cycle defective,lethal - all die before end of embryonic stage,some die during embryonic stage,rescuable maternal effect" "gastrula embryo,blastoderm embryo,rescuable maternal effect,egg,maternal effect" FBgn0039124 tbrd-1 testis-specifically expressed bromodomain containing protein-1 http://flybase.org/reports/FBgn0039124 protein_coding_gene chromatin binding ; GO:0003682 | inferred from direct assay "spermatogenesis ; GO:0007283 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011 spermatid differentiation ; GO:0048515 | inferred from mutant phenotype" precatalytic spliceosome ; GO:0071011 | inferred from direct assay chromosome ; GO:0005694 | inferred from direct assay nuclear body ; GO:0016604 | inferred from direct assay nucleolus ; GO:0005730 | inferred from direct assay "tbrd-1, CG13597, tBRD-1" "IPR001487:Bromodomain, IPR018359:Bromodomain, conserved site" CG13597 27-Aug-18 DroID_v2018_08 "Drer\brd3a, Drer\brdt, Drer\brd3b, Drer\brd4, Drer\brd2b, Drer\brd2a" "Scer\BDF2, Scer\SPT7, Scer\BDF1" "Cele\bet-1, Cele\baz-2, Cele\bet-2, Cele\F59F5.7" "Xtro\brd2, Xtro\brdt, Xtro\pbrm1, Xtro\brd3, Xtro\brd4" "Mmus\Brd2, Mmus\Baz1a, Mmus\Brd3, Mmus\Brdt, Mmus\Brd4, Mmus\Cecr2" "Hsap\BRDT, Hsap\BRD2, Hsap\BAZ1A, Hsap\BRD4, Hsap\BRD3, Hsap\CCDC127, Hsap\CECR2" "male sterile,male fertile,viable" "spermatid,Nebenkern,sperm individualization complex" FBgn0031664 CG8892 - http://flybase.org/reports/FBgn0031664 protein_coding_gene - - - CG8892 "IPR001012:UBX domain, IPR006577:UAS, IPR009060:UBA-like, IPR017346:UBX domain-containing protein 2/7, IPR012336:Thioredoxin-like fold, IPR029071:Ubiquitin-related domain" CG8892 27-Aug-18 DroID_v2018_08 Drer\ubxn7 Scer\UBX5 "Cele\C16C8.9, Cele\T05E12.6, Cele\ZK1037.6" Xtro\ubxn7 Mmus\Ubxn7 Hsap\UBXN7 viable FBgn0050355 CG30355 - http://flybase.org/reports/FBgn0050355 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs23a07, NEST:bs23e07, NEST:bs06e10, NEST:bs04f07, BcDNA:AT24812, NEST:bs10b08, CG30355" - CG30355 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0021785 l(3)02670 lethal (3) 02670 http://flybase.org/reports/FBgn0021785 - gene - - - "l(2)02670, l(3)02670" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0039641 CG14511 - http://flybase.org/reports/FBgn0039641 protein_coding_gene GDP-fucose transmembrane transporter activity ; GO:0005457 | inferred from biological aspect of ancestor with PANTHER:PTN000081450 UDP-xylose transmembrane transporter activity ; GO:0005464 | inferred from biological aspect of ancestor with PANTHER:PTN000081450 UDP-N-acetylglucosamine transmembrane transporter activity ; GO:0005462 | inferred from biological aspect of ancestor with PANTHER:PTN000081450 UDP-N-acetylglucosamine transmembrane transport ; GO:1990569 | inferred from biological aspect of ancestor with PANTHER:PTN000081450 GDP-fucose transport ; GO:0015783 | inferred from biological aspect of ancestor with PANTHER:PTN000081450 integral component of endoplasmic reticulum membrane ; GO:0030176 | inferred from biological aspect of ancestor with PANTHER:PTN000081292 Golgi medial cisterna ; GO:0005797 | inferred from direct assay integral component of Golgi membrane ; GO:0030173 | inferred from biological aspect of ancestor with PANTHER:PTN000081292 CG14511 IPR013657:UAA transporter CG14511 27-Aug-18 DroID_v2018_08 Drer\slc35b4 Scer\YEA4 "Cele\nstp-1, Cele\nstp-2" - Mmus\Slc35b4 Hsap\SLC35B4 viable FBgn0259424 EP-650 - http://flybase.org/reports/FBgn0259424 gene - - - EP-650 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing vein,wing" FBgn0053377 5SrRNA:CR33377 5SrRNA:CR33377 http://flybase.org/reports/FBgn0053377 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33377, 5SrRNA:CR33377" - CR33377 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004407 DNApol-gamma35 DNA polymerase gamma 35kD http://flybase.org/reports/FBgn0004407 "FBgn0000476, FBgn0001962, FBgn0020398, FBgn0053084, FBgn0053650, FBtr0089832, FBpp0088773, FBtr0089833, FBpp0088774" protein_coding_gene DNA-directed DNA polymerase activity ; GO:0003887 | inferred from sequence or structural similarity DNA-directed DNA polymerase activity ; GO:0003887 | inferred from sequence or structural similarity with UniProtKB:Q9UHN1 glycine-tRNA ligase activity ; GO:0004820 | inferred from biological aspect of ancestor with PANTHER:PTN000078674 axonal transport of mitochondrion ; GO:0019896 | inferred from mutant phenotype DNA-dependent DNA replication ; GO:0006261 | inferred from physical interaction with tam mitochondrial DNA replication ; GO:0006264 | traceable author statement glycyl-tRNA aminoacylation ; GO:0006426 | inferred from biological aspect of ancestor with PANTHER:PTN000078674 mitochondrion organization ; GO:0007005 | inferred from mutant phenotype DNA-dependent DNA replication ; GO:0006261 | inferred from sequence or structural similarity with UniProtKB:Q9UHN1 mitochondrial genome maintenance ; GO:0000002 | inferred from mutant phenotype mitochondrial DNA replication ; GO:0006264 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from physical interaction with tam gamma DNA polymerase complex ; GO:0005760 | inferred from physical interaction with tam mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q9UHN1 gamma DNA polymerase complex ; GO:0005760 | inferred from sequence or structural similarity "pol gamma-beta, l(2)34De, polgamma-beta, MtPolB, BG:DS00941.9, polgamma, Polgamma, l(2)br16, DNApol-gamma, br16, CG33084, CG33650, CG8969, DNApol-gamma35, DNA pol-gam.35, DNApol-gamma.35, D-pol gamma-beta, pol gamma35, PolG, Pol gamma, Polg" "IPR004154:Anticodon-binding, IPR027031:Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2" CG33650 27-Aug-18 DroID_v2018_08 "Drer\gars, Drer\polg2" "Scer\GRS1, Scer\GRS2" - "Xtro\polg2, Xtro\gars" "Mmus\Gars, Mmus\Polg2" "Hsap\GARS, Hsap\POLG2" "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage,neuroanatomy defective,locomotor behavior defective" "mitochondrion,embryonic/larval central nervous system,mitochondrionb80c1)" FBgn0025007 E(var)102-1 E(var)102-1 http://flybase.org/reports/FBgn0025007 - gene - - - "E-102/1, E(var)102-1" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002403 l(3)99Dd lethal (3) 99Dd http://flybase.org/reports/FBgn0002403 - gene - - - l(3)99Dd - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0260763 CG42561 - http://flybase.org/reports/FBgn0260763 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG14481, CG42561" - CG42561 27-Aug-18 DroID_v2018_08 - - - - - - DRSC05676 K 0.01097758 -0.362677984 -0.134144017 0.583906239 1.618992325 -0.442379407 FBgn0265810 asRNA:CR44599 - http://flybase.org/reports/FBgn0265810 non_protein_coding_gene - - - CR44599 - CR44599 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0053192 MtnD Metallothionein D http://flybase.org/reports/FBgn0053192 protein_coding_gene metal ion binding ; GO:0046872 | inferred from direct assay response to metal ion ; GO:0010038 | inferred from sequence or structural similarity with MtnE metal ion homeostasis ; GO:0055065 | inferred from mutant phenotype response to metal ion ; GO:0010038 | inferred from direct assay response to copper ion ; GO:0046688 | inferred from direct assay cellular_component ; GO:0005575 | no biological data available "CG33192, MtnD, mtnD" "IPR000966:Metallothionein, family 5, Diptera" CG33192 27-Aug-18 DroID_v2018_08 - - - - - - DRSC22733 K 0.427786275 0.495561886 1.043114874 -0.407423976 -1.582004459 0.296703443 FBgn0004075 ms(2)35Eb male sterile (2) 35Eb http://flybase.org/reports/FBgn0004075 - gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype - ms(2)35Eb - - 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,recessive" FBgn0041719 snRNA:U4:25F snRNA:U4:25F http://flybase.org/reports/FBgn0041719 snRNA_gene - "mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity" U4 snRNP ; GO:0005687 | inferred from sequence or structural similarity "U4, U4-25F, K3, U4-2, dU4, snRNA:U4, CR32998, U4snRNA, snRNA:U4:25F, U4:25F, U4 snRNA, snRNA, U425F, U4-snRNA" - CR32998 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0022045 l(2)k08306 lethal (2) k08306 http://flybase.org/reports/FBgn0022045 - gene - - - l(2)k08306 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0060655 l(3)S082908a lethal (3) S082908a http://flybase.org/reports/FBgn0060655 gene - - - "0829/08, l(3)S082908a" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0051301 CG31301 - http://flybase.org/reports/FBgn0051301 protein_coding_gene "nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000467, InterPro:IPR001374" signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN001043816 nucleolus ; GO:0005730 | inferred from biological aspect of ancestor with PANTHER:PTN001043816 nucleoplasm ; GO:0005654 | inferred from biological aspect of ancestor with PANTHER:PTN001043816 "CG31301, CG12258" "IPR000467:G-patch domain, IPR001374:R3H domain, IPR034071:NF-kappaB-repression factor, R3H domain, IPR021859:XRN-Two Binding Domain, XTBD" CG31301 27-Aug-18 DroID_v2018_08 "Drer\cdkn2aipnl, Drer\nkrf, Drer\cdkn2aip" - Cele\paxt-1 "Xtro\cdkn2aip, Xtro\cdkn2aipnl, Xtro\nkrf" "Mmus\Cdkn2aipnl, Mmus\Nkrf, Mmus\Cdkn2aip" "Hsap\CDKN2AIP, Hsap\NKRF, Hsap\CDKN2AIPNL" "viable,fertile" FBgn0067402 Rst(2)DDT-EMS2 Resistant to DDT on II EMS2 http://flybase.org/reports/FBgn0067402 gene - - - "Rst(2)DDT, Rst(2)DDT-EMS2" - - 27-Aug-18 DroID_v2018_08 - - - - - - chemical resistant FBgn0037894 Ranbp9 Ranbp9 http://flybase.org/reports/FBgn0037894 protein_coding_gene Ran GTPase binding ; GO:0008536 | inferred from electronic annotation with InterPro:IPR001494 intracellular protein transport ; GO:0006886 | inferred from electronic annotation with InterPro:IPR001494 - "CG5252, Ranbp9" "IPR001494:Importin-beta, N-terminal domain, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold" CG5252 27-Aug-18 DroID_v2018_08 Drer\ipo9 Scer\KAP114 Cele\xpo-2 Xtro\ipo9 Mmus\Ipo9 Hsap\IPO9 viable FBgn0266259 CG44954 - http://flybase.org/reports/FBgn0266259 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG44954, lincRNA.900" - CG44954 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033806 FLASH FLICE-associated huge protein http://flybase.org/reports/FBgn0033806 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Lsm11 mRNA 3'-end processing by stem-loop binding and cleavage ; GO:0006398 | inferred from mutant phenotype histone locus body ; GO:0035363 | inferred from direct assay histone pre-mRNA 3'end processing complex ; GO:0071204 | inferred from direct assay "dFLASH, FLASH, CG4616" - CG4616 27-Aug-18 DroID_v2018_08 Drer\casp8ap2 - - - Mmus\Casp8ap2 Hsap\CASP8AP2 "viable,female sterile,female semi-sterile" FBgn0036109 Cpr67Fa2 Cuticular protein 67Fa2 http://flybase.org/reports/FBgn0036109 protein_coding_gene structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "BcDNA:LP01241, CG18349, Cpr67Fa2, DmelCpr67Fa2" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG18349 27-Aug-18 DroID_v2018_08 Drer\LOC100003040 - "Cele\F44F1.4, Cele\sdz-30, Cele\math-34" - "Mmus\2410137M14Rik, Mmus\H2-K1" - FBgn0040753 CG13341 - http://flybase.org/reports/FBgn0040753 protein_coding_gene - - - CG13341 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004993 Cli Clipped wings http://flybase.org/reports/FBgn0004993 - gene - - - Cli - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible,dominant" wing FBgn0060543 l(3)S099102 lethal (3) S099102 http://flybase.org/reports/FBgn0060543 gene - - - "0991/02, l(3)S099102" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0266186 Vamp7 Vesicle-associated membrane protein 7 http://flybase.org/reports/FBgn0266186 protein_coding_gene "SNARE binding ; GO:0000149 | inferred from physical interaction with Snap29, Syx17 syntaxin binding ; GO:0019905 | inferred from sequence or structural similarity with RGD:619747 SNAP receptor activity ; GO:0005484 | inferred from physical interaction with Snap29, Syx17 SNAP receptor activity ; GO:0005484 | inferred by curator from GO:0006906,GO:0019905,GO:0031201" endocytosis ; GO:0006897 | inferred from biological aspect of ancestor with PANTHER:PTN000474284 vesicle fusion ; GO:0006906 | inferred from biological aspect of ancestor with PANTHER:PTN000473885 vesicle fusion ; GO:0006906 | inferred from sequence or structural similarity with RGD:619747 endosome to lysosome transport ; GO:0008333 | inferred from sequence or structural similarity with RGD:619747 autophagosome maturation ; GO:0097352 | inferred from mutant phenotype exocytosis ; GO:0006887 | inferred from biological aspect of ancestor with PANTHER:PTN000473885 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR001388 SNARE complex ; GO:0031201 | inferred from direct assay autolysosome ; GO:0044754 | inferred from direct assay late endosome membrane ; GO:0031902 | inferred from sequence or structural similarity with RGD:619747 SNARE complex ; GO:0031201 | inferred from sequence or structural similarity with RGD:619747 "VAMP7, CG1599, TI-VAMP, Vamp7, dVamp7" "IPR001388:Synaptobrevin, IPR010908:Longin domain, IPR011012:Longin-like domain" CG1599 27-Aug-18 DroID_v2018_08 "Drer\sybl1, Drer\vamp1, Drer\sec22bb, Drer\sec22a, Drer\zgc:92912, Drer\sec22ba, Drer\vamp8, Drer\vamp2, Drer\sec22c" Scer\NYV1 "Cele\snb-1, Cele\vamp-7, Cele\vamp-8, Cele\sec-22" "Xtro\sec22b, Xtro\vamp7, Xtro\vamp2, Xtro\sec22c, Xtro\vamp3, Xtro\vamp1, Xtro\sec22a, Xtro\ykt6, Xtro\vamp4" "Mmus\Sec22a, Mmus\Vamp1, Mmus\Ykt6, Mmus\Vamp3, Mmus\Vamp7, Mmus\Sec22c, Mmus\Vamp2, Mmus\Vamp4, Mmus\Vamp8, Mmus\Sec22b, Mmus\Gm35911" "Hsap\SEC22C, Hsap\VAMP2, Hsap\SEC22B, Hsap\VAMP8, Hsap\YKT6, Hsap\VAMP7, Hsap\VAMP1, Hsap\VAMP3, Hsap\VAMP4" FBgn0047114 CG31142 - http://flybase.org/reports/FBgn0047114 protein_coding_gene - - - "BcDNA:RE39515, CG31142" "IPR019191:Essential protein Yae1, N-terminal" CG31142 27-Aug-18 DroID_v2018_08 Drer\otulina - - Xtro\yae1d1 Mmus\Yae1d1 Hsap\YAE1D1 "viable,visible" trichogen cell FBgn0023218 E(lz)205 E(lz)205 http://flybase.org/reports/FBgn0023218 - gene - - - E(lz)205 - - 27-Aug-18 DroID_v2018_08 - - - - - - wild-type FBgn0267152 lncRNA:CR45592 - http://flybase.org/reports/FBgn0267152 non_protein_coding_gene - - - CR45592 - CR45592 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031520 CG8837 - http://flybase.org/reports/FBgn0031520 protein_coding_gene glucose transmembrane transporter activity ; GO:0005355 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 sugar:proton symporter activity ; GO:0005351 | inferred from biological aspect of ancestor with PANTHER:PTN000627328 glucose import ; GO:0046323 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 hexose transmembrane transport ; GO:0035428 | inferred from biological aspect of ancestor with PANTHER:PTN000756124 "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005828, InterPro:IPR005829" CG8837 "IPR005829:Sugar transporter, conserved site, IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain" CG8837 27-Aug-18 DroID_v2018_08 "Drer\slc2a12, Drer\slc2a10, Drer\LOC101882338, Drer\slc2a8, Drer\slc2a13b, Drer\slc2a6" "Scer\GAL2, Scer\HXT2, Scer\YDR387C, Scer\GEX2, Scer\ITR1, Scer\VBA2, Scer\HXT15, Scer\YFL040W, Scer\AZR1, Scer\ENB1, Scer\HXT9, Scer\MAL11, Scer\HXT3, Scer\GEX1, Scer\HXT7, Scer\HXT5, Scer\STL1, Scer\HXT11, Scer\HXT13, Scer\MPH2, Scer\SGE1, Scer\RGT2, Scer\ITR2, Scer\HXT4, Scer\VBA4, Scer\VBA5, Scer\SNF3, Scer\HXT17, Scer\HXT8, Scer\YDL199C, Scer\MAL31, Scer\VBA3, Scer\HXT14, Scer\MPH3, Scer\YMR279C, Scer\ATR1, Scer\HXT10, Scer\HXT16, Scer\VBA1, Scer\HXT1, Scer\HXT6" Cele\F48E3.2 "Xtro\slc2a8, Xtro\slc2a6, Xtro\slc2a12, Xtro\slc2a10" "Mmus\Slc2a13, Mmus\Slc2a10, Mmus\Slc2a8, Mmus\Slc2a6, Mmus\Slc2a12" "Hsap\SLC2A10, Hsap\SLC2A6, Hsap\SLC2A8, Hsap\SLC2A13, Hsap\SLC2A12" viable FBgn0035645 CG5592 - http://flybase.org/reports/FBgn0035645 protein_coding_gene organic anion transmembrane transporter activity ; GO:0008514 | inferred from biological aspect of ancestor with PANTHER:PTN001936837 "transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005828, InterPro:IPR011701" integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN001175408 CG5592 "IPR005828:Major facilitator, sugar transporter-like, IPR020846:Major facilitator superfamily domain, IPR011701:Major facilitator superfamily" CG5592 27-Aug-18 DroID_v2018_08 "Drer\zgc:175176, Drer\slc22a7b.3, Drer\zmp:0000001102, Drer\oatx, Drer\slc22a6l, Drer\slc22a7b.1, Drer\sv2, Drer\LOC100334012, Drer\slc22a5, Drer\slc22a7b.2, Drer\LOC101884074, Drer\slc22a21, Drer\slc22a13" "Scer\TPO2, Scer\GIT1, Scer\QDR1, Scer\DTR1, Scer\PHO84, Scer\HXT5, Scer\HXT9, Scer\YHK8, Scer\QDR3, Scer\TPO3, Scer\TPO1, Scer\AQR1, Scer\FLR1, Scer\HXT2, Scer\QDR2" "Cele\Y66D12A.13, Cele\C06H5.6, Cele\oct-1, Cele\T22F7.1, Cele\C53B4.1, Cele\Y57G11C.23, Cele\C46C2.2, Cele\ZK892.3, Cele\B0361.11, Cele\B0252.3, Cele\Y51A2D.18" Xtro\slc22a6 "Mmus\Slc22a16, Mmus\Slc22a20, Mmus\Slc22a27, Mmus\Slc22a14, Mmus\Slc22a7, Mmus\Slc22a21, Mmus\Slc22a30, Mmus\Svop, Mmus\Slc22a4, Mmus\Slc22a26, Mmus\Slc22a22, Mmus\Slc22a2, Mmus\Slc22a19, Mmus\Slc22a29, Mmus\Slc22a28, Mmus\Sv2c, Mmus\Slc22a23, Mmus\Slc22a8, Mmus\Slc22a6, Mmus\Slc22a5" "Hsap\SLC22A12, Hsap\SLC22A24, Hsap\SLC22A14, Hsap\SVOP, Hsap\SLC22A1, Hsap\SLC22A2, Hsap\SLC22A10, Hsap\SLC22A23, Hsap\SLC22A8, Hsap\SLC22A7, Hsap\SLC22A11, Hsap\SLC22A13, Hsap\SLC22A4, Hsap\SV2C, Hsap\SLC22A5, Hsap\SLC22A25, Hsap\SLC22A9, Hsap\SV2B, Hsap\SLC22A6" "partially lethal - majority die,some die during pupal stage" FBgn0266523 Nadsyn::Mmus\Ube4b - http://flybase.org/reports/FBgn0266523 engineered_fusion_gene - - - "CG9940::Mmus\Ube4b, Nadsyn::Mmus\Ube4b" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065459 l(2)SH1382 lethal (2) SH1382 http://flybase.org/reports/FBgn0065459 gene - - - "l(2)SH1382, l(2)SH2 1382" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0037004 CG17637 - http://flybase.org/reports/FBgn0037004 protein_coding_gene transporter activity ; GO:0005215 | inferred from biological aspect of ancestor with PANTHER:PTN001921112 transmembrane transport ; GO:0055085 | inferred from biological aspect of ancestor with PANTHER:PTN001921112 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011701 CG17637 "IPR001958:Tetracycline resistance protein TetA/multidrug resistance protein MdtG, IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG17637 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-87m7.2, Drer\LOC557306, Drer\si:ch211-262i1.4, Drer\LOC100002406, Drer\slc46a3, Drer\slc46a1, Drer\zgc:174356, Drer\hiat1b, Drer\si:dkey-5g14.1, Drer\hiat1a" Scer\YJL163C "Cele\F40F9.5, Cele\C46C11.2, Cele\T25D3.4, Cele\Y4C6B.5, Cele\Y71G12B.25" "Xtro\mfsd14b, Xtro\slc46a1, Xtro\mfsd14a" "Mmus\Slc46a2, Mmus\Mfsd14b, Mmus\Slc46a1, Mmus\Slc46a3, Mmus\Mfsd14a" "Hsap\SLC46A1, Hsap\SLC46A2, Hsap\MFSD14B, Hsap\SLC46A3, Hsap\MFSD14A" FBgn0034540 Lrt Leucine-rich tendon-specific protein http://flybase.org/reports/FBgn0034540 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with robo1 negative regulation of muscle cell chemotaxis toward tendon cell ; GO:2001282 | inferred from mutant phenotype Roundabout signaling pathway involved in muscle cell chemotaxis toward tendon cell ; GO:2001283 | inferred from genetic interaction with robo1 protein complex ; GO:0043234 | inferred from physical interaction with robo1 muscle tendon junction ; GO:0005927 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from direct assay "tartan/capricious-like, CT31131, Lrt, CG11136, lrt" "IPR000483:Cysteine-rich flanking region, C-terminal, IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like" CG11136 27-Aug-18 DroID_v2018_08 "Drer\nyx, Drer\flrt1a, Drer\flrt1b, Drer\lrit2, Drer\flrt3, Drer\lrit3b, Drer\lrrc24" Scer\CYR1 "Cele\clec-1, Cele\lron-11" "Xtro\slitrk2, Xtro\slitrk1, Xtro\flrt1, Xtro\LOC100488097, Xtro\flrt3, Xtro\nyx, Xtro\tril" "Mmus\Nyx, Mmus\Flrt1, Mmus\Lrit2, Mmus\Pkd1, Mmus\Flrt3, Mmus\Tril, Mmus\Rtn4rl2, Mmus\Lrrc24, Mmus\Lgi4" "Hsap\LRRC24, Hsap\LRIT2, Hsap\AMIGO2, Hsap\RTN4RL2, Hsap\LRRC70, Hsap\FLRT3, Hsap\PKD1, Hsap\FLRT1, Hsap\NYX" viable "ventral longitudinal muscle,embryonic/larval somatic muscle,A1-7 ventral oblique muscle 4,A1-7 ventral acute muscle 3" DRSC06045 E -0.790561286 0.424615961 -0.107030463 1.665103435 -0.043728304 0.44673536 FBgn0262315 mir-2493 mir-2493 stem loop http://flybase.org/reports/FBgn0262315 miRNA_gene - - - "mir-2493, CR43022, dme-mir-2493, dme-miR-2493-5p" - CR43022 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0034903 sona sol narae http://flybase.org/reports/FBgn0034903 protein_coding_gene metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR001590 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001590 positive regulation of Wnt signaling pathway ; GO:0030177 | inferred from mutant phenotype inferred from genetic interaction with wg imaginal disc-derived appendage development ; GO:0048737 | inferred from mutant phenotype endosome ; GO:0005768 | inferred from direct assay extracellular matrix ; GO:0031012 | inferred from direct assay Golgi-associated vesicle ; GO:0005798 | inferred from direct assay "dimp, Dimp, CG11169, CG9850, sona" "IPR001590:Peptidase M12B, ADAM/reprolysin, IPR024079:Metallopeptidase, catalytic domain, IPR034030:Salivary gland reprolysin domain, IPR011990:Tetratricopeptide-like helical domain" CG9850 27-Aug-18 DroID_v2018_08 "Drer\adamts15a, Drer\LOC100002059, Drer\adamtsl5, Drer\adamts18, Drer\adamtsl3, Drer\adamts8a, Drer\thsd7bb, Drer\adamts13, Drer\adamts12, Drer\adamts6, Drer\adamts2, Drer\adamts7, Drer\adamts1, Drer\adamtsl2, Drer\LOC568792" - Cele\mig-17 "Xtro\adamts18, Xtro\adamts7, Xtro\adamts15, Xtro\adamts16, Xtro\adamts20, Xtro\adamts12, Xtro\adamts6, Xtro\adamts9" "Mmus\Adamts6, Mmus\Adamts13, Mmus\Adamts20, Mmus\Adamts8, Mmus\Thsd7a, Mmus\Adamts1, Mmus\Adamts12, Mmus\Adamts9, Mmus\Adamts4, Mmus\Adamts16, Mmus\Adamts7, Mmus\Thsd4, Mmus\Adamts18, Mmus\Adamtsl4, Mmus\Adamtsl1, Mmus\Sspo, Mmus\Adamts10, Mmus\Adamtsl5, Mmus\Adamts19, Mmus\Adamts5, Mmus\Adamts15, Mmus\Adamts14" "Hsap\ADAMTSL1, Hsap\ADAMTS7, Hsap\ADAMTS16, Hsap\ADAMTSL5, Hsap\ADAMTS19, Hsap\ADAMTS6, Hsap\ADAMTS8, Hsap\ADAMTS12, Hsap\ADAMTS13, Hsap\THSD4, Hsap\ADAMTS15, Hsap\ADAMDEC1, Hsap\ADAMTS18, Hsap\ADAMTS10, Hsap\ADAM17, Hsap\ADAMTSL4, Hsap\ADAMTS20, Hsap\ADAMTS9, Hsap\THSD7B, Hsap\ADAMTS4, Hsap\ADAMTS5, Hsap\ADAMTS17, Hsap\ADAMTS14, Hsap\ADAMTS1" "viable,fertile" DRSC04089 E -0.253965377 0.560930084 1.780878089 0.499976519 -0.495817229 0.746732139 FBgn0263599 l(3)72Ab lethal (3) 72Ab http://flybase.org/reports/FBgn0263599 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011545 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR011545 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from sequence or structural similarity with SGD:S000000974 RNA helicase activity ; GO:0003724 | inferred from sequence or structural similarity "regulation of alternative mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype RNA splicing ; GO:0008380 | inferred from sequence or structural similarity ventral cord development ; GO:0007419 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013 mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with UniProtKB:O75643" catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay nucleus ; GO:0005634 | inferred by curator from GO:0000381 nucleus ; GO:0005634 | inferred from direct assay small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from physical interaction with Prp8 spliceosomal complex ; GO:0005681 | inferred from sequence or structural similarity with UniProtKB:O75643 "brr2, CG5931, l(3)72Ab, ASCC3L1, Brr2, cg5931, clone 1.21, anon-EST:Liang-1.21" "IPR011991:Winged helix-turn-helix DNA-binding domain, IPR001650:Helicase, C-terminal, IPR004179:Sec63 domain, IPR011545:DEAD/DEAH box helicase domain, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR014756:Immunoglobulin E-set, IPR000008:C2 domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG5931 27-Aug-18 DroID_v2018_08 "Drer\ascc3, Drer\snrnp200, Drer\hfm1" "Scer\HFM1, Scer\SLH1, Scer\BRR2" "Cele\dnj-29, Cele\Y54E2A.4, Cele\snrp-200" Xtro\snrnp200 "Mmus\Snrnp200, Mmus\Ascc3, Mmus\Hfm1" "Hsap\HFM1, Hsap\SNRNP200, Hsap\ASCC3" DRSC10559 IE -0.824683325 2.703476299 -2.048692294 -0.893859185 -1.160825837 -0.489464655 FBgn0034345 CG5174 - http://flybase.org/reports/FBgn0034345 protein_coding_gene - - - "BcDNA:RH27395, BcDNA:RE18604, CG5174" IPR007327:Tumour protein D52 CG5174 27-Aug-18 DroID_v2018_08 "Drer\tpd52l2b, Drer\tpd52l2a, Drer\tpd52, Drer\tpd52l1" - Cele\F13E6.1 "Xtro\tpd52, Xtro\tpd52l1" "Mmus\Trpd52l3, Mmus\Tpd52l2, Mmus\Tpd52, Mmus\Tpd52l1" "Hsap\TPD52L3, Hsap\TPD52L2, Hsap\TPD52, Hsap\TPD52L1" "viable,fertile" FBgn0020819 l(3)98Dk lethal (3) 98Dk http://flybase.org/reports/FBgn0020819 - gene - - - "M31, l(3)98Dk" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0069408 JJF178 JJF178 http://flybase.org/reports/FBgn0069408 gene - - - JJF178 - - 27-Aug-18 DroID_v2018_08 - - - - - - stress response defective FBgn0060687 l(3)S074913 lethal (3) S074913 http://flybase.org/reports/FBgn0060687 gene - - - "0749/13, l(3)S074913" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0013610 l(3)E8-3-54 lethal (3) E8-3-54 http://flybase.org/reports/FBgn0013610 - gene - - - l(3)E8-3-54 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0264549 lncRNA:CR43928 - http://flybase.org/reports/FBgn0264549 non_protein_coding_gene - - - CR43928 - CR43928 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060751 l(3)S064912 lethal (3) S064912 http://flybase.org/reports/FBgn0060751 gene - - - "0649/12, l(3)S064912" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0053465 CG33465 - http://flybase.org/reports/FBgn0053465 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314" - "BP1080, CR33465, HDC06631, CG33465" "IPR001314:Peptidase S1A, chymotrypsin family, IPR001254:Serine proteases, trypsin domain, IPR009003:Peptidase S1, PA clan" CG33465 27-Aug-18 DroID_v2018_08 "Drer\masp2, Drer\LOC558805" - Cele\try-3 - - Hsap\PRSS54 FBgn0044324 Chro Chromator http://flybase.org/reports/FBgn0044324 protein_coding_gene "histone binding ; GO:0042393 | inferred from physical interaction with His1 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:A1Z8P9 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VCH5,UniProtKB:Q9VGA4,UniProtKB:Q9VP57" chromosome organization ; GO:0051276 | inferred from mutant phenotype chromosome segregation ; GO:0007059 | inferred from mutant phenotype mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype metaphase plate congression ; GO:0051310 | inferred from mutant phenotype mitotic spindle assembly checkpoint ; GO:0007094 | inferred from mutant phenotype metamorphosis ; GO:0007552 | inferred from mutant phenotype centrosome ; GO:0005813 | inferred from direct assay spindle ; GO:0005819 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay polytene chromosome interband ; GO:0005705 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay "Chriz, Chr, CG10712, anon-EST:fe2E3, Chro, CHRO, Chromator, Chiz, CHRIZ, CHRIZ/CHRO, Chro(Chriz)" "IPR000953:Chromo/chromo shadow domain, IPR016197:Chromo domain-like, IPR023780:Chromo domain, IPR029058:Alpha/Beta hydrolase fold" CG10712 27-Aug-18 DroID_v2018_08 "Drer\cbx3a, Drer\cbx3b" - "Cele\set-31, Cele\hpl-1" - Mmus\Cbx3 Hsap\CBX3 "lethal - all die before end of P-stage,some die during P-stage,lethal - all die before end of embryonic stage,some die during embryonic stage,viable,visible,lethal - all die before end of pupal stage,some die during pupal stage,mitotic cell cycle defective,size defective,lethal - all die before end of larval stage,some die during third instar larval stage" "abdominal temporary eclosion muscle DA,A1-7 dorsal oblique muscle,wing,embryonic/larval neuroblast,imaginal disc,embryonic/larval brain,spindle | third instar larval stage,polytene chromosome" DRSC11630 EK -1.202313509 -1.343129555 -1.505271314 -1.25953784 2.164606305 0.181784419 FBgn0036324 CG12520 - http://flybase.org/reports/FBgn0036324 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model "CG12520, FBgn0036324" "IPR001810:F-box domain, IPR032675:Leucine-rich repeat domain, L domain-like" CG12520 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,some die during pupal stage" FBgn0265730 lncRNA:CR44537 - http://flybase.org/reports/FBgn0265730 non_protein_coding_gene - - - "CR44537, incRNA.408, lincRNA.408" - CR44537 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0050027 CG30027 - http://flybase.org/reports/FBgn0050027 protein_coding_gene - - - CG30027 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264384 lncRNA:CR43836 - http://flybase.org/reports/FBgn0264384 non_protein_coding_gene - - - CR43836 - CR43836 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263539 mir-4978 mir-4978 stem loop http://flybase.org/reports/FBgn0263539 miRNA_gene - - - "mir-4978, dme-mir-4978, CR43524" - CR43524 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264469 asRNA:CR43877 - http://flybase.org/reports/FBgn0264469 non_protein_coding_gene - - - CR43877 - CR43877 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267524 2SrRNA:CR45864 2S ribosomal RNA:CR45864 http://flybase.org/reports/FBgn0267524 rRNA_gene - - - "2SrRNA:CR45864, CR45864" - CR45864 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0022311 l(1)J30.4 lethal (1) J30.4 http://flybase.org/reports/FBgn0022311 - gene - - - "J30.4, l(1)J30.4" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0060926 l(3)S042203b lethal (3) S042203b http://flybase.org/reports/FBgn0060926 gene - - - "0422/03, l(3)S042203b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0020060 E(spl)m8-HLH::h E(spl)::h http://flybase.org/reports/FBgn0020060 - engineered_fusion_gene - - - "E(spl)::h, E(spl)m8-HLH::h" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,female" FBgn0061096 l(3)S009911 lethal (3) S009911 http://flybase.org/reports/FBgn0061096 gene - - - "0099/11, l(3)S009911" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0262509 nrm neuromusculin http://flybase.org/reports/FBgn0262509 protein_coding_gene molecular_function ; GO:0003674 | no biological data available synaptic target recognition ; GO:0008039 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from sequence or structural similarity inferred from direct assay "nrm, CG32458, CG43079, CT16082, CG8779, CG41452, CG4307" "IPR003599:Immunoglobulin subtype, IPR007110:Immunoglobulin-like domain, IPR013106:Immunoglobulin V-set domain, IPR013162:CD80-like, immunoglobulin C2-set, IPR013783:Immunoglobulin-like fold, IPR003598:Immunoglobulin subtype 2" CG43079 27-Aug-18 DroID_v2018_08 Drer\si:dkey-234i14.9 - Cele\egl-15 "Xtro\LOC100498328, Xtro\LOC100497709, Xtro\LOC100216153" "Mmus\Ceacam11, Mmus\Psg27, Mmus\Psg19, Mmus\F830045P16Rik, Mmus\Psg23, Mmus\Btnl2, Mmus\Sirpa, Mmus\Ceacam10, Mmus\Sirpb1a, Mmus\Psg28, Mmus\Psg18, Mmus\Psg26, Mmus\Psg16, Mmus\Ceacam14, Mmus\Psg17, Mmus\Psg21, Mmus\Hepacam, Mmus\Ceacam13, Mmus\Gm5155, Mmus\Ceacam5, Mmus\Ceacam12, Mmus\Ceacam9, Mmus\Psg25, Mmus\Psg29, Mmus\Psg22" "Hsap\SIRPG, Hsap\HEPACAM2, Hsap\CD276, Hsap\SIRPB1, Hsap\SIRPA, Hsap\CRTAM" " embryonic stage | stage >=15 , embryonic stage | stage 9-12 , embryonic stage | stage 9 " " larval muscle system

, embryonic peripheral nervous system

, sensory mother cell

" FBgn0062526 l(3)88EFf lethal (3) 88EFf http://flybase.org/reports/FBgn0062526 gene - - - l(3)88EFf - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0005056 fs(2)OW102 female sterile (2) OW102 http://flybase.org/reports/FBgn0005056 - gene - - - fs(2)OW102 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266261 CG44956 - http://flybase.org/reports/FBgn0266261 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44956 - CG44956 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065083 snmRNA:765 small non-messenger RNA 765 http://flybase.org/reports/FBgn0065083 non_protein_coding_gene - - - "Dm-765, CR33789, snmRNA:765" - CR33789 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004225 l(3)84Fm lethal (3) 84Fm http://flybase.org/reports/FBgn0004225 - gene - - - l(3)84Fm - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0035255 RabX5 RabX5 http://flybase.org/reports/FBgn0035255 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR005225 GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with Rab11" vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with Rab11 Rab protein signal transduction ; GO:0032482 | inferred from sequence or structural similarity with Rab11 vesicle ; GO:0031982 | inferred from sequence or structural similarity with Rab11 synapse ; GO:0045202 | inferred from direct assay "DmRabX5, CG7980, RabX5, rabX5, Q9W0A7" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG7980 27-Aug-18 DroID_v2018_08 "Drer\rab34a, Drer\rab34b, Drer\rpl23a, Drer\rab36" "Scer\TEM1, Scer\RHO4, Scer\RPL25, Scer\YPT6" "Cele\Y71H2AM.12, Cele\C56E6.2" "Xtro\rab34, Xtro\rpl23a, Xtro\rab36" "Mmus\Rpl23a, Mmus\Rab36, Mmus\Rab34" "Hsap\NARR, Hsap\RAB36, Hsap\RAB34, Hsap\RPL23A" "viable,fertile" FBgn0037705 mura murashka http://flybase.org/reports/FBgn0037705 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin protein ligase activity ; GO:0061630 | inferred from biological aspect of ancestor with PANTHER:PTN001021049 ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:18052 long-term memory ; GO:0007616 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with HGNC:18052 learning or memory ; GO:0007611 | inferred from mutant phenotype regulation of response to DNA damage stimulus ; GO:2001020 | inferred from genetic interaction with lok behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN001021049 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:18052 "CG9381, CG9382, mura, Mura" "IPR001841:Zinc finger, RING-type, IPR015943:WD40/YVTN repeat-like-containing domain, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG9381 27-Aug-18 DroID_v2018_08 "Drer\wu:fb39e10, Drer\rnf44, Drer\rnf126, Drer\rnf32, Drer\rnf11a, Drer\zswim2, Drer\si:dkey-51a16.9, Drer\rnf38, Drer\rnf24, Drer\rlim, Drer\rnf165a, Drer\znrf3, Drer\rnf103, Drer\rnf165b, Drer\rnf11b, Drer\rnf130, Drer\rnf6, Drer\rnf215, Drer\si:ch211-81a5.1, Drer\si:ch1073-392o20.1, Drer\rnf150, Drer\rnf115, Drer\pja2, Drer\rnf111, Drer\rnf150a, Drer\zgc:175214" "Scer\ASR1, Scer\YBR062C" "Cele\toe-4, Cele\plr-1" "Xtro\rnf11, Xtro\rlim, Xtro\rnf24, Xtro\rnf181, Xtro\rnf115, Xtro\znrf3, Xtro\rnf149, Xtro\rnf11.2, Xtro\rnf32, Xtro\chmp3, Xtro\rnf44, Xtro\rnf111, Xtro\pja2, Xtro\rnf38, Xtro\rnf126" "Mmus\Rnf24, Mmus\Rnf44, Mmus\Znrf3, Mmus\Rnf43, Mmus\Rnf165, Mmus\Rnf111, Mmus\Rnf126, Mmus\Rnf103, Mmus\Pja2, Mmus\Rnf181, Mmus\Rnf130, Mmus\Rnf150, Mmus\Rnf11, Mmus\4930595M18Rik, Mmus\Rnf38, Mmus\Rnf215, Mmus\Rnf149, Mmus\Pja1, Mmus\Rnf122, Mmus\Rnf115, Mmus\Rlim, Mmus\Rnf32, Mmus\Rnf6, Mmus\Zswim2" "Hsap\ZNRF3, Hsap\RNF43, Hsap\CHMP3, Hsap\RNF6, Hsap\RNF215, Hsap\PJA1, Hsap\RNF130, Hsap\RNF149, Hsap\RNF181, Hsap\RNF150, Hsap\RNF103, Hsap\RNF122, Hsap\RNF11, Hsap\RNF24, Hsap\RNF38, Hsap\PJA2, Hsap\RNF126, Hsap\RNF115, Hsap\RNF44, Hsap\RLIM, Hsap\ZSWIM2, Hsap\RNF111, Hsap\RNF165, Hsap\RNF32" "viable,fertile,learning defective,memory defective,chemical resistant" DRSC23145 K 1.603695716 -0.197794796 FBgn0046880 Obp56b Odorant-binding protein 56b http://flybase.org/reports/FBgn0046880 protein_coding_gene odorant binding ; GO:0005549 | inferred from sequence or structural similarity with lush odorant binding ; GO:0005549 | inferred from sequence or structural similarity with UniProtKB:P34174 odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with lush sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 sensory perception of smell ; GO:0007608 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with UniProtKB:P34174 extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000220814 extracellular region ; GO:0005576 | inferred from sequence model "56b, CG15129, OBP56b, CG30129, Obp56b, DmelObp56b" IPR006170:Pheromone/general odorant binding protein CG30129 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0029079 icln icln http://flybase.org/reports/FBgn0029079 protein_coding_gene - spliceosomal snRNP assembly ; GO:0000387 | inferred from electronic annotation with InterPro:IPR003521 cell volume homeostasis ; GO:0006884 | inferred from electronic annotation with InterPro:IPR003521 chloride transport ; GO:0006821 | inferred from electronic annotation with InterPro:IPR003521 plasma membrane ; GO:0005886 | inferred from electronic annotation with InterPro:IPR003521 pICln-Sm protein complex ; GO:0034715 | inferred from electronic annotation with InterPro:IPR003521 cytosol ; GO:0005829 | inferred from electronic annotation with InterPro:IPR003521 methylosome ; GO:0034709 | inferred from electronic annotation with InterPro:IPR003521 "CG4924, icln, pICln" IPR003521:ICln CG4924 27-Aug-18 DroID_v2018_08 Drer\clns1a Scer\LOT5 "Cele\icln-1, Cele\icl-1" Xtro\clns1a Mmus\Clns1a Hsap\CLNS1A viable FBgn0040041 CG17506 - http://flybase.org/reports/FBgn0040041 protein_coding_gene - - - "CG40223, CG17506" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264708 lncRNA:CR43977 - http://flybase.org/reports/FBgn0264708 non_protein_coding_gene - - - CR43977 - CR43977 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0016900 l(3)72CDb lethal (3) 72CDb http://flybase.org/reports/FBgn0016900 - gene - - - l(3)72CDb - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,viable" FBgn0036998 CG5969 - http://flybase.org/reports/FBgn0036998 protein_coding_gene - vacuolar proton-transporting V-type ATPase complex assembly ; GO:0070072 | inferred from electronic annotation with InterPro:IPR019013 sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - "BcDNA:GM09417, BcDNA:RE53796, CG32426, CG5969" IPR019013:Vacuolar ATPase assembly integral membrane protein Vma21 CG5969 27-Aug-18 DroID_v2018_08 "Drer\qpct, Drer\vma21" Scer\VMA21 "Cele\R07E5.7, Cele\H27A22.1, Cele\pdcd-2" "Xtro\vma21, Xtro\qpct" "Mmus\Qpct, Mmus\Vma21" "Hsap\QPCT, Hsap\QPCTL, Hsap\VMA21" "viable,fertile,visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum FBgn0085202 CG34173 - http://flybase.org/reports/FBgn0085202 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34173 - CG34173 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262979 lncRNA:CR43287 - http://flybase.org/reports/FBgn0262979 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CR43287, CG43287" - CR43287 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0029740 CG12680 - http://flybase.org/reports/FBgn0029740 protein_coding_gene - - - CG12680 - CG12680 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0264395 CG43843 - http://flybase.org/reports/FBgn0264395 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43843, CG15049" - CG43843 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004524 l(4)102EFa lethal (4) 102EFa http://flybase.org/reports/FBgn0004524 - gene - - - "l(4)9, l(4)BU-1, l(4)1-JFC, l(4)102EFa" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of pupal stage,some die during pupal stage" FBgn0002043 l(2)37Dg lethal (2) 37Dg http://flybase.org/reports/FBgn0002043 - gene - - - "l(2)OE39, l(2)37Dg" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0037093 Cdk12 Cyclin-dependent kinase 12 http://flybase.org/reports/FBgn0037093 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441 cyclin-dependent protein serine/threonine kinase activity ; GO:0004693 | inferred from biological aspect of ancestor with PANTHER:PTN000623091 transcription factor binding ; GO:0008134 | inferred from biological aspect of ancestor with PANTHER:PTN000623455 cyclin binding ; GO:0030332 | inferred from biological aspect of ancestor with PANTHER:PTN000623455 cyclin-dependent protein serine/threonine kinase activity ; GO:0004693 | inferred from sequence or structural similarity cyclin binding ; GO:0030332 | inferred from physical interaction with UniProtKB:Q961D1 transcription regulatory region DNA binding ; GO:0044212 | inferred from biological aspect of ancestor with PANTHER:PTN000623455 RNA polymerase II carboxy-terminal domain kinase activity ; GO:0008353 | inferred from sequence or structural similarity with SGD:S000001622 cyclin-dependent protein serine/threonine kinase activity ; GO:0004693 | inferred from sequence or structural similarity with SGD:S000001622 RNA polymerase II carboxy-terminal domain kinase activity ; GO:0008353 | inferred from direct assay" positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with Ras85D protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity phosphorylation of RNA polymerase II C-terminal domain ; GO:0070816 | inferred from direct assay neurogenesis ; GO:0022008 | inferred from mutant phenotype positive regulation of peptide hormone secretion ; GO:0090277 | inferred from mutant phenotype positive regulation of multicellular organism growth ; GO:0040018 | inferred from mutant phenotype positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from genetic interaction with Ras85D protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with SGD:S000001622 phagocytosis ; GO:0006909 | inferred from mutant phenotype phosphorylation of RNA polymerase II C-terminal domain ; GO:0070816 | inferred from biological aspect of ancestor with PANTHER:PTN000623455 transcription elongation from RNA polymerase II promoter ; GO:0006368 | inferred from biological aspect of ancestor with PANTHER:PTN000623455 positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from biological aspect of ancestor with PANTHER:PTN000623455 polytene chromosome puff ; GO:0005703 | inferred from direct assay nuclear chromosome ; GO:0000228 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay cyclin/CDK positive transcription elongation factor complex ; GO:0008024 | inferred from biological aspect of ancestor with PANTHER:PTN000623455 nuclear cyclin-dependent protein kinase holoenzyme complex ; GO:0019908 | inferred from direct assay "AC017581, anon-WO0140519.165, gi24668141, CG7597, cg7597, Cdk12, dCDK12, CDK12" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG7597 27-Aug-18 DroID_v2018_08 "Drer\cdk13, Drer\cdk9, Drer\prpf4bb, Drer\akt3b" "Scer\SGV1, Scer\SNF1, Scer\SWE1, Scer\CTK1, Scer\FPK1" "Cele\cdk-12, Cele\cdk-9" "Xtro\cdk12, Xtro\cdk9, Xtro\prpf4b, Xtro\cdk13" "Mmus\Cdk13, Mmus\Cdk9, Mmus\Cdk12, Mmus\Prpf4b" "Hsap\CDK9, Hsap\CDK12, Hsap\CDK13" "lethal,neuroanatomy defective,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval neuroblast,ganglion mother cell" DRSC11836 I -2.145831887 3.612852403 1.160552934 -0.263228052 -0.605919049 -0.430251493 FBgn0034198 CG11400 - http://flybase.org/reports/FBgn0034198 protein_coding_gene - - - CG11400 - CG11400 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065794 l(2)SH0419 lethal (2) SH0419 http://flybase.org/reports/FBgn0065794 gene - - - "l(2)SH0419, l(2)SH2 0419" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0065184 l(3)06142b lethal (3) 06142b http://flybase.org/reports/FBgn0065184 gene - - - "l(3)06142, l(3)06142b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0036279 Ncc69 sodium chloride cotransporter 69 http://flybase.org/reports/FBgn0036279 protein_coding_gene amino acid transmembrane transporter activity ; GO:0015171 | inferred from sequence or structural similarity with Eaat1 sodium:potassium:chloride symporter activity ; GO:0008511 | inferred from direct assay chloride transport ; GO:0006821 | inferred from direct assay amino acid transmembrane transport ; GO:0003333 | inferred from sequence or structural similarity with Eaat1 potassium ion transport ; GO:0006813 | inferred from mutant phenotype potassium ion transport ; GO:0006813 | inferred from direct assay rubidium ion transport ; GO:0035826 | inferred from direct assay integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR004842 plasma membrane ; GO:0005886 | inferred from direct assay "CG4357, CG43567, CK01027, NCC69, BEST:CK01027, Ncc69, mdcds_25302" "IPR002443:Na/K/Cl co-transporter, IPR004841:Amino acid permease/ SLC12A domain, IPR004842:SLC12A transporter family, IPR018491:SLC12A transporter, C-terminal" CG4357 27-Aug-18 DroID_v2018_08 "Drer\slc12a10.3, Drer\slc12a10.1, Drer\slc12a2, Drer\slc12a10.2, Drer\slc12a8, Drer\slc12a1, Drer\slc12a3" Scer\VHC1 "Cele\nkcc-1, Cele\B0303.11" "Xtro\slc12a2, Xtro\slc12a3, Xtro\slc12a1" "Mmus\Slc12a2, Mmus\Slc12a3, Mmus\Slc12a1, Mmus\Slc12a8" "Hsap\SLC12A1, Hsap\SLC12A8, Hsap\SLC12A2, Hsap\SLC12A3" "viable,neuroanatomy defective,fertile,bang sensitive,paralytic" "abdominal nerve,abdominal nerve | third instar larval stage" DRSC10413 I 1.940446653 1.702325733 0.728097408 1.081331537 -0.191863888 -0.223638111 FBgn0051053 CG31053 - http://flybase.org/reports/FBgn0051053 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model SUMO transferase activity ; GO:0019789 | inferred from biological aspect of ancestor with PANTHER:PTN001099470 synapsis ; GO:0007129 | inferred from biological aspect of ancestor with PANTHER:PTN001099470 protein sumoylation ; GO:0016925 | inferred from biological aspect of ancestor with PANTHER:PTN001099470 synaptonemal complex ; GO:0000795 | inferred from biological aspect of ancestor with PANTHER:PTN001099470 CG31053 "IPR001841:Zinc finger, RING-type, IPR017907:Zinc finger, RING-type, conserved site, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG31053 27-Aug-18 DroID_v2018_08 - Scer\CST9 "Cele\D1081.9, Cele\zhp-3, Cele\F55A12.10, Cele\R06C7.2, Cele\Y39B6A.16" - "Mmus\Rnf212b, Mmus\Rnf212" "Hsap\RNF212B, Hsap\RNF212" viable FBgn0069942 CG41101 - http://flybase.org/reports/FBgn0069942 protein_coding_gene - - - CG41101 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0015782 Pa Puffrmel http://flybase.org/reports/FBgn0015782 - gene - - - Pa - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,dominant" wing FBgn0017444 anon-15Dc anon-15Dc http://flybase.org/reports/FBgn0017444 - gene - - - anon-15Dc - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004035 yea1 yeast 1 http://flybase.org/reports/FBgn0004035 - gene - - - yea1 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002142 l(2)K327 lethal (2) K327 http://flybase.org/reports/FBgn0002142 - gene - - - l(2)K327 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0002769 mit(1)21 mitotic 21 http://flybase.org/reports/FBgn0002769 - gene - - - mit(1)21 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267322 lncRNA:CR45758 - http://flybase.org/reports/FBgn0267322 non_protein_coding_gene - - - CR45758 - CR45758 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265853 lncRNA:CR44642 - http://flybase.org/reports/FBgn0265853 non_protein_coding_gene - - - CR44642 - CR44642 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0022153 l(2)k05819 lethal (2) k05819 http://flybase.org/reports/FBgn0022153 FBgn0044723 protein_coding_gene nucleotide binding ; GO:0000166 | inferred from electronic annotation with InterPro:IPR023299 molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG3054, anon-WO0140519.156, l(2)k05819" "IPR023214:HAD-like domain, IPR023299:P-type ATPase, cytoplasmic domain N, IPR023298:P-type ATPase, transmembrane domain" CG3054 27-Aug-18 DroID_v2018_08 Drer\tmem94 - Cele\D1007.15 Xtro\tmem94 Mmus\Tmem94 Hsap\TMEM94 "lethal,recessive,viable,fertile" FBgn0032373 Vha100-5 Vacuolar H[+] ATPase 100kD subunit 5 http://flybase.org/reports/FBgn0032373 protein_coding_gene "proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from sequence or structural similarity with SGD:S000005796 ATPase binding ; GO:0051117 | inferred from biological aspect of ancestor with PANTHER:PTN000179505 proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from biological aspect of ancestor with PANTHER:PTN000179505" vacuolar proton-transporting V-type ATPase complex assembly ; GO:0070072 | inferred from biological aspect of ancestor with PANTHER:PTN000179505 ATP synthesis coupled proton transport ; GO:0015986 | inferred from biological aspect of ancestor with PANTHER:PTN000179505 ATP hydrolysis coupled proton transport ; GO:0015991 | inferred from sequence or structural similarity with SGD:S000005796 vacuolar acidification ; GO:0007035 | inferred from biological aspect of ancestor with PANTHER:PTN000179505 "vacuolar proton-transporting V-type ATPase complex ; GO:0016471 | inferred from biological aspect of ancestor with PANTHER:PTN000179505 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000907964 vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220 | inferred from sequence or structural similarity with SGD:S000005796" "CG12602, Vha100-5, vha100-5" "IPR002490:V-type ATPase, V0 complex, 116kDa subunit family, IPR026028:ATPase, V0 complex, subunit 116kDa, eukaryotic" CG12602 27-Aug-18 DroID_v2018_08 "Drer\tcirg1b, Drer\si:ch73-173p19.2, Drer\atp6v0a2a, Drer\atp6v0a1a, Drer\atp6v0a1b, Drer\tcirg1a, Drer\atp6v0a2b" "Scer\STV1, Scer\VPH1" "Cele\vha-7, Cele\unc-32, Cele\vha-6, Cele\vha-5" "Xtro\atp6v0a4, Xtro\tcirg1, Xtro\atp6v0a1, Xtro\atp6v0a2" "Mmus\Atp6v0a4, Mmus\Tcirg1, Mmus\Atp6v0a2, Mmus\Atp6v0a1" "Hsap\ATP6V0A2, Hsap\ATP6V0A1, Hsap\ATP6V0A4, Hsap\TCIRG1" "visible,viable" wing DRSC02175 IEK 1.635735752 -1.118750573 -1.286887755 -2.065949073 1.529998519 0.080140718 FBgn0082939 snoRNA:Me28S-C3227b snoRNA:Me28S-C3227b http://flybase.org/reports/FBgn0082939 snoRNA_gene - - - "snoRNA:Me28S-C3227b, Me28S-Cm3227b, CR34534" - CR34534 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0044073 E(rst)J25 E(rst)J25 http://flybase.org/reports/FBgn0044073 gene molecular_function ; GO:0003674 | no biological data available compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with rst cellular_component ; GO:0005575 | no biological data available "J25, E(rst)J25" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267084 asRNA:CR45528 - http://flybase.org/reports/FBgn0267084 non_protein_coding_gene - - - CR45528 - CR45528 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034425 CG11906 - http://flybase.org/reports/FBgn0034425 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - "11906, CG11906" IPR013087:Zinc finger C2H2-type CG11906 27-Aug-18 DroID_v2018_08 "Drer\aga, Drer\im:7147486, Drer\zgc:153169, Drer\znf142" Scer\RME1 - Xtro\aga "Mmus\Aga, Mmus\Zfp574, Mmus\Zfp142" "Hsap\ZNF142, Hsap\AGA, Hsap\ZNF33A, Hsap\ZNF574" "viable,fertile" FBgn0266513 s-523.2 - http://flybase.org/reports/FBgn0266513 gene - - - s-523.2 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034950 Pask PAS kinase http://flybase.org/reports/FBgn0034950 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441 protein kinase activity ; GO:0004672 | non-traceable author statement protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with HGNC:17270" regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with HGNC:17270 protein phosphorylation ; GO:0006468 | non-traceable author statement nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:17270 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with HGNC:17270 "pask, Pask, CG3105" "IPR000014:PAS domain, IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain, IPR017441:Protein kinase, ATP binding site" CG3105 27-Aug-18 DroID_v2018_08 "Drer\pask, Drer\pim3, Drer\LOC108179363, Drer\zgc:66101" "Scer\PSK2, Scer\PSK1" "Cele\kin-33, Cele\prk-2" Xtro\pim3 "Mmus\Sik3, Mmus\Pask, Mmus\Pim1, Mmus\Pim3, Mmus\Pim2" "Hsap\PIM3, Hsap\PASK, Hsap\PIM2, Hsap\SIK3" viable FBgn0262752 Mst77Y-3Psi Male-specific pseudogene 77Y 3 http://flybase.org/reports/FBgn0262752 pseudogene_attribute - - - Mst77Y-3Psi - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0019733 l(1)A13 lethal (1) A13 http://flybase.org/reports/FBgn0019733 - gene - - - l(1)A13 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0010622 DCTN3-p24 "Dynactin 3, p24 subunit" http://flybase.org/reports/FBgn0010622 FBgn0034813 protein_coding_gene - microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity regulation of hemocyte proliferation ; GO:0035206 | inferred from mutant phenotype dynactin complex ; GO:0005869 | inferred from sequence or structural similarity with MGI:MGI:1859251 dynactin complex ; GO:0005869 | inferred from sequence or structural similarity "CG9893, l(2)06496, p24, l(2)06 496, p22/p24, DCTN3, DCTN3-p24, P24" IPR009991:Dynactin subunit p22 CG9893 27-Aug-18 DroID_v2018_08 Drer\dctn3 - - - Mmus\Dctn3 Hsap\DCTN3 "lethal,recessive" FBgn0060461 l(3)S115510b lethal (3) S115510b http://flybase.org/reports/FBgn0060461 gene - - - "1155/10, l(3)S115510b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0052398 CG32398 - http://flybase.org/reports/FBgn0052398 protein_coding_gene - - - CG32398 - - 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0040329 EY3-2 EY3-2 http://flybase.org/reports/FBgn0040329 gene - - - EY3-2 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0000124 Ars-region2 Autonomous replicating sequence region 2 http://flybase.org/reports/FBgn0000124 - region - - - "DmARS-2, Ars-region2, Ars2" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034162 CG6426 - http://flybase.org/reports/FBgn0034162 protein_coding_gene lysozyme activity ; GO:0003796 | inferred from electronic annotation with InterPro:IPR008597 multicellular organism reproduction ; GO:0032504 | inferred from expression pattern extracellular space ; GO:0005615 | inferred from direct assay "l(2)k04810, n(2)k04810, BcDNA:RH01665, CG6426" IPR008597:Destabilase CG6426 27-Aug-18 DroID_v2018_08 - - "Cele\ilys-3, Cele\ilys-4, Cele\ilys-6, Cele\ilys-1, Cele\ilys-5, Cele\ilys-2" - - - "viable,fertile" FBgn0036469 CG18649 - http://flybase.org/reports/FBgn0036469 protein_coding_gene - - - "BcDNA:RE73239, CG18649" - CG18649 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC10334 IK 1.514783743 1.90338617 0.33761691 -0.227576919 -0.502353603 1.602338918 FBgn0035299 CG11815 - http://flybase.org/reports/FBgn0035299 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available mitochondrial respiratory chain complex I ; GO:0005747 | inferred from electronic annotation with InterPro:IPR026193 cellular_component ; GO:0005575 | no biological data available CG11815 IPR026193:NADH-ubiquinone oxidoreductase flavoprotein 3 CG11815 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0038608 WRNexo WRN exonuclease http://flybase.org/reports/FBgn0038608 protein_coding_gene "nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR002562, InterPro:IPR012337 single-stranded DNA 3'-5' exodeoxyribonuclease activity ; GO:0008310 | inferred from direct assay double-stranded DNA 3'-5' exodeoxyribonuclease activity ; GO:0008311 | inferred from direct assay 3'-5' exonuclease activity ; GO:0008408 | inferred from sequence or structural similarity with HGNC:12791 3'-5' exonuclease activity ; GO:0008408 | inferred from mutant phenotype" "replication fork protection ; GO:0048478 | inferred from genetic interaction with spn-A negative regulation of mitotic recombination ; GO:0045950 | inferred from mutant phenotype DNA catabolic process, exonucleolytic ; GO:0000738 | inferred from direct assay DNA catabolic process, exonucleolytic ; GO:0000738 | inferred by curator from GO:0008408" nucleus ; GO:0005634 | inferred from direct assay "WRNexo, CG7670, DmWRNexo" "IPR002562:3'-5' exonuclease domain, IPR012337:Ribonuclease H-like domain" CG7670 27-Aug-18 DroID_v2018_08 "Drer\wrn, Drer\exd2" - Cele\wrn-1 "Xtro\wrn, Xtro\exd2" "Mmus\Exd2, Mmus\Wrn" "Hsap\WRN, Hsap\EXD2" "viable,fertile,female sterile,male fertile,chemical sensitive,partially lethal - majority die,some die during pupal stage" DRSC16278 K 0.267051824 0.122949397 0.463713755 0.412671518 1.965578096 -1.673582142 FBgn0069075 ttf tintenfisch http://flybase.org/reports/FBgn0069075 gene molecular_function ; GO:0003674 | no biological data available "anterior/posterior axis specification, embryo ; GO:0008595 | inferred from mutant phenotype" cellular_component ; GO:0005575 | no biological data available ttf - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,germline clone,non-rescuable maternal effect,recessive" "embryonic thorax,germline clone,maternal effect,embryonic head,embryonic abdominal segment 7,embryonic abdominal segment 8" FBgn0268063 ltl larval translucida http://flybase.org/reports/FBgn0268063 protein_coding_gene - imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from direct assay "ltl, l(3)tr, lincRNA.S4366, CG32372, CG7545, CT15760, F, CG14836, anon-EST:CL1a11" "IPR032675:Leucine-rich repeat domain, L domain-like, IPR026906:Leucine rich repeat 5, IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype" CG32372 27-Aug-18 DroID_v2018_08 "Drer\chadlb, Drer\chadla" - - Xtro\slitrk6 "Mmus\Gp1ba, Mmus\Tlr4" Hsap\TLR4 FBgn0026249 ego early germ cell overproliferation http://flybase.org/reports/FBgn0026249 - gene - - - ego - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035211 CG2211 - http://flybase.org/reports/FBgn0035211 protein_coding_gene - - - "anon-WO0118547.230, CG2211" - CG2211 27-Aug-18 DroID_v2018_08 - - Cele\jmjd-4 - - Hsap\JMJD6 viable FBgn0060369 l(3)S138102 lethal (3) S138102 http://flybase.org/reports/FBgn0060369 gene - - - "1381/02, l(3)S138102" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0083981 RunxA Runt related A http://flybase.org/reports/FBgn0083981 protein_coding_gene "transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from electronic annotation with InterPro:IPR008967, InterPro:IPR012346, InterPro:IPR013524 ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000040 DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR000040, InterPro:IPR012346, InterPro:IPR013524" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR000040, InterPro:IPR008967, InterPro:IPR012346, InterPro:IPR013524 dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype" "nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR000040, InterPro:IPR012346" "CG1379, CG15453, CG34145, RunxA" "IPR000040:Acute myeloid leukemia 1 protein (AML1)/Runt, IPR008967:p53-like transcription factor, DNA-binding, IPR012346:p53/RUNT-type transcription factor, DNA-binding domain, IPR013524:Runt domain" CG34145 27-Aug-18 DroID_v2018_08 "Drer\runx2b, Drer\runx1, Drer\runx3, Drer\runx2a" - Cele\rnt-1 "Xtro\runx3, Xtro\runx2, Xtro\runx1" "Mmus\Runx3, Mmus\Runx1, Mmus\Runx2" "Hsap\RUNX1, Hsap\RUNX3, Hsap\RUNX2" "lethal,neuroanatomy defective" "dorsal multidendritic neuron ddaC,abdominal anterior ventral multidendritic neuron vdaa" FBgn0025141 ms(3)A6 ms(3)A6 http://flybase.org/reports/FBgn0025141 - gene - - - ms(3)A6 - - 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,recessive" FBgn0267738 asRNA:CR46069 - http://flybase.org/reports/FBgn0267738 non_protein_coding_gene - - - "CR46069, Mgn94068" - CR46069 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032175 CG13131 - http://flybase.org/reports/FBgn0032175 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13131 - CG13131 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile" FBgn0259478 EP-336 - http://flybase.org/reports/FBgn0259478 gene - - - EP-336 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing,wing margin,chaeta,ectopic" FBgn0265197 CG44257 - http://flybase.org/reports/FBgn0265197 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44257 - CG44257 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0023085 fcG fcG http://flybase.org/reports/FBgn0023085 - gene - - - fcG - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0083000 snoRNA:Psi28S-1192b snoRNA:Psi28S-1192b http://flybase.org/reports/FBgn0083000 snoRNA_gene - - - "snoRNA:Psi28S-1192b, Psi28S-1192b, psi28S-1192b, CR34596, chrX:16978184..16978371" - CR34596 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001589 l(1)carot6 lethal (1) carot6 http://flybase.org/reports/FBgn0001589 - gene - - - l(1)carot6 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0265610 CG44428 - http://flybase.org/reports/FBgn0265610 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG44428 - CG44428 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032787 CG10195 - http://flybase.org/reports/FBgn0032787 protein_coding_gene "hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR000086, InterPro:IPR015797" - - CG10195 "IPR000086:NUDIX hydrolase domain, IPR015797:NUDIX hydrolase domain-like" CG10195 27-Aug-18 DroID_v2018_08 Drer\nudt19 - Cele\ndx-7 Xtro\nudt19 Mmus\Nudt19 Hsap\NUDT19 "viable,fertile" DRSC02026 I 0.919479269 2.004256654 -0.465537298 0.716693186 -0.803214372 -0.06901763 FBgn0053688 CG33688 - http://flybase.org/reports/FBgn0053688 protein_coding_gene molecular_function ; GO:0003674 | no biological data available lateral inhibition ; GO:0046331 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available CG33688 IPR010512:Protein of unknown function DUF1091 CG33688 27-Aug-18 DroID_v2018_08 - - Cele\K12H4.7 - - - "viable,visible" chaeta FBgn0043848 412\ORF2 412 element ORF2 http://flybase.org/reports/FBgn0043848 transposable_element_gene - - - "412\ORF2, ORF2" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085493 CG40506 - http://flybase.org/reports/FBgn0085493 protein_coding_gene - - - CG40506 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0082636 S(CycE[JP])1S3 S(CycE[JP])1S3 http://flybase.org/reports/FBgn0082636 gene - - - "1S3, S(CycE[JP])1S3" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0014993 l(3)90DEa lethal (3) 90DEa http://flybase.org/reports/FBgn0014993 - gene - - - "l(3)5D4, l(3)90DEa" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0015969 l(2)55Da lethal (2) 55Da http://flybase.org/reports/FBgn0015969 - gene - - - l(2)55Da - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0025782 anon-MMS91 anon-MMS91 http://flybase.org/reports/FBgn0025782 - gene - - - anon-MMS91 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265256 CG44270 - http://flybase.org/reports/FBgn0265256 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG44270, lincRNA.207" - CG44270 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0027509 TBCD tubulin folding cofactor D http://flybase.org/reports/FBgn0027509 - protein_coding_gene beta-tubulin binding ; GO:0048487 | inferred from sequence or structural similarity with HGNC:11581 GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with HGNC:11581 beta-tubulin binding ; GO:0048487 | inferred from biological aspect of ancestor with PANTHER:PTN000291965 GTPase activator activity ; GO:0005096 | inferred from biological aspect of ancestor with PANTHER:PTN000291965 post-chaperonin tubulin folding pathway ; GO:0007023 | inferred from electronic annotation with InterPro:IPR033162 adherens junction assembly ; GO:0034333 | inferred from biological aspect of ancestor with PANTHER:PTN000974682 dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype tubulin complex assembly ; GO:0007021 | inferred from biological aspect of ancestor with PANTHER:PTN000291965 microtubule cytoskeleton organization ; GO:0000226 | inferred from mutant phenotype axonogenesis ; GO:0007409 | inferred from mutant phenotype bicellular tight junction assembly ; GO:0070830 | inferred from biological aspect of ancestor with PANTHER:PTN000974682 microtubule cytoskeleton organization involved in mitosis ; GO:1902850 | inferred from genetic interaction with Arl2 protein folding ; GO:0006457 | inferred from biological aspect of ancestor with PANTHER:PTN000291965 positive regulation of GTPase activity ; GO:0043547 | inferred from sequence or structural similarity with HGNC:11581 establishment or maintenance of neuroblast polarity ; GO:0045196 | inferred from genetic interaction with Arl2 protein folding ; GO:0006457 | inferred from sequence or structural similarity with HGNC:11581 negative regulation of microtubule polymerization ; GO:0031115 | inferred from sequence or structural similarity with HGNC:11581 positive regulation of GTPase activity ; GO:0043547 | inferred from biological aspect of ancestor with PANTHER:PTN000291965 lateral plasma membrane ; GO:0016328 | inferred from biological aspect of ancestor with PANTHER:PTN000974682 adherens junction ; GO:0005912 | inferred from biological aspect of ancestor with PANTHER:PTN000974682 bicellular tight junction ; GO:0005923 | inferred from biological aspect of ancestor with PANTHER:PTN000974682 microtubule ; GO:0005874 | inferred from biological aspect of ancestor with PANTHER:PTN000291965 "CG7261, BcDNA:LD22320, TBCD, tbcd" "IPR016024:Armadillo-type fold, IPR022577:Tubulin-specific chaperone D, C-terminal, IPR011989:Armadillo-like helical, IPR033162:Tubulin-folding cofactor D" CG7261 27-Aug-18 DroID_v2018_08 Drer\tbcd Scer\CIN1 Cele\tbcd-1 Xtro\tbcd Mmus\Tbcd Hsap\TBCD "viable,visible" trichogen cell FBgn0035031 CG13587 - http://flybase.org/reports/FBgn0035031 protein_coding_gene transmembrane signaling receptor activity ; GO:0004888 | inferred from biological aspect of ancestor with PANTHER:PTN000177070 - integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000177070 CG13587 "IPR001304:C-type lectin-like, IPR016186:C-type lectin-like/link domain, IPR016187:C-type lectin fold" CG13587 27-Aug-18 DroID_v2018_08 "Drer\si:dkeyp-94g1.1, Drer\zgc:162060, Drer\si:dkey-28d5.14, Drer\si:dkey-83f18.11, Drer\si:dkey-28d5.3, Drer\si:dkey-81n2.2, Drer\si:ch211-282j17.11, Drer\si:dkey-88n24.9, Drer\si:dkey-88n24.8, Drer\si:dkey-88n24.10, Drer\mrc1a, Drer\mrc2, Drer\si:ch211-282j17.1, Drer\mrc1b, Drer\si:ch211-272h9.3, Drer\si:dkey-11o15.4, Drer\si:ch211-282j17.3, Drer\LOC101886741, Drer\pla2r1, Drer\si:ch211-63p21.4, Drer\si:dkey-28d5.10, Drer\si:dkey-28d5.12, Drer\si:ch211-282j17.10, Drer\si:dkey-88n24.7, Drer\si:dkey-83f18.7, Drer\si:dkey-83f18.15, Drer\si:ch211-225k7.6, Drer\si:dkey-88n24.6, Drer\si:dkey-83f18.3, Drer\si:ch211-225k7.3, Drer\si:dkey-83f18.9, Drer\si:ch211-225k7.2, Drer\si:ch211-282j17.7, Drer\si:dkey-28d5.4, Drer\si:ch211-225k7.4, Drer\si:dkey-83f18.10, Drer\si:ch211-225k7.5, Drer\si:dkey-81n2.1, Drer\si:dkey-28d5.13, Drer\si:ch73-335d12.2, Drer\si:dkey-192d15.3, Drer\ly75, Drer\si:dkey-83f18.5, Drer\si:dkey-28d5.9, Drer\si:ch211-282j17.8, Drer\LOC101885237, Drer\si:dkey-28d5.8" - "Cele\clec-49, Cele\clec-50, Cele\clec-48" - "Mmus\Mrc1, Mmus\Pla2r1, Mmus\Cd302, Mmus\Mrc2, Mmus\Ly75" "Hsap\REG1A, Hsap\CLEC10A, Hsap\MRC1, Hsap\LY75, Hsap\CD302, Hsap\PLA2R1, Hsap\ASGR1, Hsap\MRC2, Hsap\CLEC4M, Hsap\CLEC17A" viable FBgn0267069 lncRNA:CR45513 - http://flybase.org/reports/FBgn0267069 non_protein_coding_gene - - - CR45513 - CR45513 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034570 CG10543 - http://flybase.org/reports/FBgn0034570 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 gravitaxis ; GO:0042332 | inferred from mutant phenotype - CG10543 "IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR015943:WD40/YVTN repeat-like-containing domain, IPR013087:Zinc finger C2H2-type" CG10543 27-Aug-18 DroID_v2018_08 "Drer\LOC100535506, Drer\si:dkeyp-2e4.8, Drer\zgc:174623, Drer\zgc:171422, Drer\si:dkey-253d23.2, Drer\zgc:172128, Drer\zgc:113119, Drer\zgc:113452" Scer\ZAP1 "Cele\let-391, Cele\eor-1, Cele\ztf-23" - - - "gravitaxis defective,viable" FBgn0010470 Fkbp14 FK506-binding protein 14 http://flybase.org/reports/FBgn0010470 "FBgn0027068, FBgn0064945" protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 FK506 binding ; GO:0005528 | inferred from biological aspect of ancestor with PANTHER:PTN000054102 FK506 binding ; GO:0005528 | inferred from sequence or structural similarity peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from sequence or structural similarity peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from biological aspect of ancestor with PANTHER:PTN000054102 chaeta development ; GO:0022416 | inferred from mutant phenotype regulation of Notch signaling pathway ; GO:0008593 | inferred from genetic interaction with Dl inferred from genetic interaction with Psn imaginal disc development ; GO:0007444 | inferred from mutant phenotype muscle cell cellular homeostasis ; GO:0046716 | inferred from mutant phenotype inferred from genetic interaction with Dg chaperone-mediated protein folding ; GO:0061077 | inferred from biological aspect of ancestor with PANTHER:PTN000054102 imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype endoplasmic reticulum ; GO:0005783 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000054102 endomembrane system ; GO:0012505 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay "FKB13, BcDNA.GM07659, l(2)00734, GM07659, CG9847, BcDNA:GM07659, BcDNA:GH08925, Fkbp13, FKBP13, fkbp13, Fkbp14, FKBP14" "IPR018247:EF-Hand 1, calcium-binding site, IPR001179:FKBP-type peptidyl-prolyl cis-trans isomerase domain, IPR002048:EF-hand domain, IPR023566:Peptidyl-prolyl cis-trans isomerase, FKBP-type, IPR011992:EF-hand domain pair" CG9847 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-208h16.4, Drer\fkbp14, Drer\fkbp1ab, Drer\fkbp10a, Drer\fkbp11, Drer\fkbp7, Drer\fkbp2, Drer\fkbp10b, Drer\fkbp1aa, Drer\fkbp1b, Drer\si:ch73-199g24.2, Drer\fkbp9" Scer\FPR2 "Cele\fkb-2, Cele\fkb-3, Cele\fkb-5, Cele\fkb-4, Cele\fkb-7, Cele\fkb-1" "Xtro\fkbp9, Xtro\fkbp15, Xtro\fkbp7, Xtro\fkbp1b, Xtro\fkbp10, Xtro\fkbp14, Xtro\fkbp3" "Mmus\Fkbp3, Mmus\Fkbp9, Mmus\Fkbp2, Mmus\Fkbp1b, Mmus\Fkbp15, Mmus\Fkbp1a, Mmus\Fkbp14, Mmus\Fkbp10, Mmus\Fkbp11, Mmus\Fkbp7" "Hsap\FKBP14, Hsap\FKBP11, Hsap\FKBP2, Hsap\FKBP1B, Hsap\FKBP10, Hsap\FKBP7, Hsap\FKBP5, Hsap\FKBP15, Hsap\FKBP9, Hsap\FKBP3" "lethal - all die before end of P-stage,lethal,female sterile,germline clone,cell lethal,somatic clone,viable,behavior defective,recessive,long lived,male limited,starvation stress response defective,temperature response defective,female limited,gravitaxis defective,fertile,neuroanatomy defective" "mesothoracic bristle,notal microchaeta,wing margin,wing margin bristle,sensory mother cell,wing disc,imaginal disc,synapse" FBgn0263769 lncRNA:CR43686 - http://flybase.org/reports/FBgn0263769 non_protein_coding_gene - - - CR43686 - CR43686 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0021985 l(2)k09837 lethal (2) k09837 http://flybase.org/reports/FBgn0021985 - gene - - - l(2)k09837 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0025797 Su(var)401 Suppressor of variegation 401 http://flybase.org/reports/FBgn0025797 - gene - - - "Su-var(2)401, Su(var)401" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0082945 snoRNA:Me28S-A2634b snoRNA:Me28S-A2634b http://flybase.org/reports/FBgn0082945 snoRNA_gene - - - "snoRNA:Me28S-A2634b, Me28S-Am2634b, CR34635, Me28S-A2634b" - CR34635 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266114 asRNA:CR44840 - http://flybase.org/reports/FBgn0266114 non_protein_coding_gene - - - CR44840 - CR44840 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033294 Mal-A4 Maltase A4 http://flybase.org/reports/FBgn0033294 protein_coding_gene "catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR006047, InterPro:IPR015902" "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR006047, InterPro:IPR006589, InterPro:IPR013781" - "Mal-A4, mal_A4, CG8693, Drome_A4" "IPR006047:Glycosyl hydrolase, family 13, catalytic domain, IPR017853:Glycoside hydrolase superfamily" CG8693 27-Aug-18 DroID_v2018_08 "Drer\slc3a2a, Drer\zgc:158423, Drer\si:dkey-202g17.3, Drer\slc3a2b, Drer\slc3a1" "Scer\IMA4, Scer\IMA1, Scer\IMA5, Scer\IMA2, Scer\MAL12, Scer\IMA3, Scer\MAL32" "Cele\atgp-2, Cele\atgp-1" "Xtro\slc3a2, Xtro\slc3a1" "Mmus\Slc3a2, Mmus\Slc3a1" "Hsap\SLC3A1, Hsap\SLC3A2" viable DRSC07236 K -0.625453206 -0.343737192 0.532224439 -0.705245538 -0.502000565 1.876948051 FBgn0045840 lambdaDsubFC4 lambdaDsubFC4 http://flybase.org/reports/FBgn0045840 gene - - - lambdaDsubFC4 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040987 CG15139 - http://flybase.org/reports/FBgn0040987 protein_coding_gene - - - CG15139 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0086077 snoRNA:Me18S-G962 - http://flybase.org/reports/FBgn0086077 snoRNA_gene - - - "snoRNA:Me18S-G962, Me18S-Gm962, CR34706" - CR34706 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000935 fs(2)A5 female sterile (2) A5 http://flybase.org/reports/FBgn0000935 - gene - - - fs(2)A5 - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive" female reproductive system FBgn0053983 obst-H obstructor-H http://flybase.org/reports/FBgn0053983 protein_coding_gene chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557 chitin binding ; GO:0008061 | inferred from reviewed computational analysis chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557 extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557 "CG17014, CG7973, obst-H, CG7973(short), CG33983, FBgn0036507" IPR002557:Chitin binding domain CG33983 27-Aug-18 DroID_v2018_08 - - "Cele\R02F2.4, Cele\cpg-2, Cele\C39D10.7, Cele\cpg-1" - - - viable FBgn0065182 l(3)SH001 lethal (3) SH001 http://flybase.org/reports/FBgn0065182 gene - - - "l(3)SH001, l(2)SH3 001" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0266589 lncRNA:CR45114 - http://flybase.org/reports/FBgn0266589 non_protein_coding_gene - - - "CR45114, lincRNA.452" - CR45114 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0022075 l(2)k07713 lethal (2) k07713 http://flybase.org/reports/FBgn0022075 - gene - - - l(2)k07713 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0021917 l(2)k11325 lethal (2) k11325 http://flybase.org/reports/FBgn0021917 - gene - - - l(2)k11325 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0069171 mcl(3)Z0589 mcl(3)Z0589 http://flybase.org/reports/FBgn0069171 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z0589 - - 27-Aug-18 DroID_v2018_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0016861 l(1)N9 lethal (1) N9 http://flybase.org/reports/FBgn0016861 - gene - - - "l(1)N9, N9" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0020774 vi vena interrupta http://flybase.org/reports/FBgn0020774 - gene - - - vi - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265888 lncRNA:CR44677 - http://flybase.org/reports/FBgn0265888 non_protein_coding_gene - - - "CR44677, lincRNA.626" - CR44677 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0067045 U12 U12 http://flybase.org/reports/FBgn0067045 gene - - - U12 - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,lethal" chaeta FBgn0004550 l(4)102CDv lethal (4) 102CDv http://flybase.org/reports/FBgn0004550 - gene - - - "l(4)37, l(4)102CDv" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0262709 ifm(2)RS2 - http://flybase.org/reports/FBgn0262709 gene - flight ; GO:0060361 | inferred from mutant phenotype adult somatic muscle development ; GO:0007527 | inferred from mutant phenotype - ifm(2)RS2 - - 27-Aug-18 DroID_v2018_08 - - - - - - "flightless,recessive" dorsal medial muscle FBgn0043375 EP1216b EP1216b http://flybase.org/reports/FBgn0043375 gene - - - EP1216b - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "macrochaeta,ectopic,trichogen cell,tormogen cell" FBgn0067661 pup poulpe http://flybase.org/reports/FBgn0067661 gene molecular_function ; GO:0003674 | no biological data available pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available pup - - 27-Aug-18 DroID_v2018_08 - - - - - - "egg chamber,germline clone" FBgn0058244 CG40244 - http://flybase.org/reports/FBgn0058244 protein_coding_gene - - - CG40244 - - 27-Aug-18 DroID_v2018_08 - - - - - - DRSC21814 IEK 5.560697221 -2.22747849 10.01167853 -0.067034215 -7.683167223 -5.327016062 FBgn0051767 CR31767 - http://flybase.org/reports/FBgn0051767 non_protein_coding_gene - - - CR31767 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060725 l(3)S068016 lethal (3) S068016 http://flybase.org/reports/FBgn0060725 gene - - - "0680/16, l(3)S068016" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0040493 grsm granny smith http://flybase.org/reports/FBgn0040493 protein_coding_gene "aminopeptidase activity ; GO:0004177 | inferred from electronic annotation with InterPro:IPR000819, InterPro:IPR011356 metalloexopeptidase activity ; GO:0008235 | inferred from electronic annotation with InterPro:IPR011356 manganese ion binding ; GO:0030145 | inferred from electronic annotation with InterPro:IPR011356" proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000819 cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR011356 "BcDNA:LD41548, CG7340, l(3)c00064, grsm, granny-smith, granny smith" "IPR000819:Peptidase M17, leucyl aminopeptidase, C-terminal, IPR011356:Peptidase M17, leucine aminopeptidase/peptidase B" CG7340 27-Aug-18 DroID_v2018_08 "Drer\lap3, Drer\zgc:152830, Drer\npepl1" - "Cele\lap-2, Cele\lap-1" "Xtro\lap3, Xtro\npepl1" "Mmus\Lap3, Mmus\Npepl1" "Hsap\LAP3, Hsap\NPEPL1" "lethal,recessive,viable,fertile" FBgn0036159 CG7557 - http://flybase.org/reports/FBgn0036159 protein_coding_gene - - - "anon-WO0140519.44, CG7557" IPR027417:P-loop containing nucleoside triphosphate hydrolase CG7557 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0004069 fs(2)mel3 female sterile (2) maternal effect lethal 3 http://flybase.org/reports/FBgn0004069 - gene - - - "mel 3, fs(2)mel3" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,recessive,some die during embryonic stage" "chorion | maternal effect,dorsal appendage,maternal effect,egg,pole cell,amnioproctodeal invagination,abdominal segment 5,abdominal segment 6,abdominal segment 7,abdominal segment 8,cephalic furrow,abdominal segment 2,abdominal segment 3,abdominal segment 4,embryonic/larval posterior spiracle,filzkorper,embryonic head" FBgn0014924 anon-72ABh anon-72ABh http://flybase.org/reports/FBgn0014924 - gene - - - anon-72ABh - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004441 prd8 paired-like 8 http://flybase.org/reports/FBgn0004441 - gene - - - prd8 - - 27-Aug-18 DroID_v2018_08 - - - - - - " oogenesis stage , embryonic stage | <8-12 hr " FBgn0033677 CG8321 - http://flybase.org/reports/FBgn0033677 protein_coding_gene - - - CG8321 IPR029383:ADP-ribosylation factor-like protein 6-interacting protein 6 CG8321 27-Aug-18 DroID_v2018_08 Drer\arl6ip6 - - - Mmus\Arl6ip6 Hsap\ARL6IP6 "learning defective,viable" FBgn0032104 aust australin http://flybase.org/reports/FBgn0032104 protein_coding_gene DNA binding ; GO:0003677 | inferred from direct assay mitotic sister chromatid segregation ; GO:0000070 | inferred from biological aspect of ancestor with PANTHER:PTN001815752 male meiosis sister chromatid cohesion ; GO:0007065 | inferred from mutant phenotype male meiosis cytokinesis ; GO:0007112 | inferred from mutant phenotype male meiosis chromosome segregation ; GO:0007060 | inferred from mutant phenotype chromosome passenger complex ; GO:0032133 | inferred from direct assay kinetochore ; GO:0000776 | colocalizes_with inferred from direct assay meiotic spindle midzone ; GO:1990385 | colocalizes_with inferred from direct assay "CG17009, aust" IPR018867:Cell division protein borealin CG17009 27-Aug-18 DroID_v2018_08 "Drer\cdca9, Drer\cdca8" - - "Xtro\cdca8, Xtro\cdca9" Mmus\Cdca8 Hsap\CDCA8 "viable,visible,cytokinesis defective,male,meiotic cell cycle defective,male sterile" mesothoracic tergum FBgn0023178 Pdf Pigment-dispersing factor http://flybase.org/reports/FBgn0023178 "FBgn0044602, FBgn0044606, FBgn0047045" protein_coding_gene hormone activity ; GO:0005179 | inferred from electronic annotation with InterPro:IPR009396 neuropeptide hormone activity ; GO:0005184 | non-traceable author statement receptor binding ; GO:0005102 | inferred from physical interaction with UniProtKB:Q9W4Y2 neuropeptide hormone activity ; GO:0005184 | traceable author statement "circadian sleep/wake cycle ; GO:0042745 | inferred from genetic interaction with ITP gravitaxis ; GO:0042332 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | inferred from mutant phenotype neuropeptide signaling pathway ; GO:0007218 | inferred from expression pattern circadian rhythm ; GO:0007623 | traceable author statement neuropeptide signaling pathway ; GO:0007218 | traceable author statement eclosion rhythm ; GO:0008062 | traceable author statement circadian rhythm ; GO:0007623 | inferred from mutant phenotype positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway ; GO:0010579 | inferred from direct assay neuropeptide signaling pathway ; GO:0007218 | inferred from direct assay circadian sleep/wake cycle ; GO:0042745 | inferred from mutant phenotype gravitaxis ; GO:0042332 | inferred from direct assay locomotor rhythm ; GO:0045475 | non-traceable author statement entrainment of circadian clock by photoperiod ; GO:0043153 | inferred from mutant phenotype regulation of circadian sleep/wake cycle ; GO:0042749 | inferred from mutant phenotype mating behavior ; GO:0007617 | inferred from mutant phenotype regulation of locomotor rhythm ; GO:1904059 | inferred from mutant phenotype locomotor rhythm ; GO:0045475 | traceable author statement positive regulation of circadian sleep/wake cycle, wakefulness ; GO:0010841 | inferred from mutant phenotype circadian rhythm ; GO:0007623 | inferred from expression pattern circadian rhythm ; GO:0007623 | non-traceable author statement" extracellular space ; GO:0005615 | inferred from direct assay extracellular region ; GO:0005576 | inferred by curator from GO:0005184 "pdf, PDF, cPDH, PAP, PDH, Drm-PDH, Drm-pdf, Drm-PDF, CG6496, BcDNA:RH08487, anon-WO0140519.3, anon-WO0140519.261, Pdf" IPR009396:Pigment-dispersing hormone CG6496 27-Aug-18 DroID_v2018_08 - - - - - - adult stage adult head

larval stage | third instar " cell body &&of larval lateral neuron

, larval lateral neuron

" "locomotor rhythm defective,mating rhythm defective,mating defective,recessive,circadian rhythm defective,photoperiod response variant,behavior defective,gravitaxis defective,circadian behavior defective,body color defective,partially lethal - majority die,some die during pupal stage" "LNv neuron,LNd neuron,mesothoracic tergum" DRSC16786 K 0.958538982 -0.114084029 -0.66076399 -0.057835684 1.864466002 0.203631205 FBgn0028622 qsm quasimodo http://flybase.org/reports/FBgn0028622 protein_coding_gene - locomotor rhythm ; GO:0045475 | inferred from mutant phenotype cell morphogenesis ; GO:0000902 | inferred from sequence or structural similarity with dyl - "qsm, CG13432, l(2)k009920, EP2356, EP2587, CG13433, l(2)05510, lethal (2) 05510, L(2)05510, QSM" IPR001507:Zona pellucida domain CG13432 27-Aug-18 DroID_v2018_08 - - "Cele\cutl-2, Cele\T01D1.8, Cele\cutl-5, Cele\cut-1, Cele\cutl-14, Cele\cutl-28, Cele\cutl-10, Cele\cut-5, Cele\cutl-20, Cele\cutl-25, Cele\cutl-17, Cele\cutl-9, Cele\cutl-7, Cele\cutl-16, Cele\cutl-6, Cele\cutl-12, Cele\cutl-26, Cele\cutl-15, Cele\F46G11.6, Cele\cutl-1, Cele\cutl-29, Cele\cutl-24, Cele\cut-4, Cele\cutl-8, Cele\cutl-19, Cele\noah-1, Cele\cutl-3, Cele\cutl-13, Cele\cut-3, Cele\cutl-18, Cele\cutl-22, Cele\cutl-11, Cele\cut-6, Cele\dpy-1, Cele\cutl-4, Cele\ram-5" - - - "lethal,recessive,viable,visible,lethal - all die before end of pupal stage,some die during pupal stage,locomotor rhythm defective,neuroanatomy defective" "adult thorax,ommatidium,eye,embryonic/larval salivary gland,dorsocentral bristle,scutellar bristle,trichogen cell,tormogen cell,intersegmental nerve,anterior fascicle & synapse | supernumerary,embryonic/larval central nervous system,wing" DRSC06393 I -0.998993484 -1.853041451 -0.784492151 -0.266703295 0.316416831 0.206354582 FBgn0052405 Cpr65Av Cuticular protein 65Av http://flybase.org/reports/FBgn0052405 protein_coding_gene structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "CG10461, BcDNA:RE31218, Cpr65Av, CG32405, DmelCpr65Av" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG32405 27-Aug-18 DroID_v2018_08 Drer\LOC100003040 - "Cele\math-34, Cele\sdz-30, Cele\F44F1.4" - "Mmus\H2-K1, Mmus\2410137M14Rik" - viable FBgn0011172 l(1)291-9 lethal (1) 291-9 http://flybase.org/reports/FBgn0011172 FBgn0010199 gene - - - "291-9, l(1)291-9" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0085622 CG41336 - http://flybase.org/reports/FBgn0085622 protein_coding_gene - - - CG41336 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034739 CG3927 - http://flybase.org/reports/FBgn0034739 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR004088 RNA binding ; GO:0003723 | inferred from sequence model lateral inhibition ; GO:0046331 | inferred from mutant phenotype nuclear speck ; GO:0016607 | inferred from direct assay "CG3927, cg3927, BcDNA:AT29209" "IPR004087:K Homology domain, IPR004088:K Homology domain, type 1" CG3927 27-Aug-18 DroID_v2018_08 "Drer\khdrbs2, Drer\qkib, Drer\khdrbs1b, Drer\qki2, Drer\khdrbs1a, Drer\khdrbs3, Drer\qkia" Scer\MSL5 "Cele\sfa-1, Cele\K07H8.9, Cele\gld-1, Cele\Y57G11C.36, Cele\asd-2, Cele\B0280.11, Cele\F54D1.1" "Xtro\khdrbs3, Xtro\khdrbs2, Xtro\khdrbs1, Xtro\qki" "Mmus\Qk, Mmus\Khdrbs2, Mmus\Sf1, Mmus\Khdrbs1, Mmus\Khdrbs3" "Hsap\KHDRBS2, Hsap\SF1, Hsap\KHDRBS1, Hsap\QKI, Hsap\KHDRBS3" "male fertile,viable,fertile,visible" "chaeta,trichogen cell,supernumerary,tormogen cell" DRSC04433 K -0.088671866 0.721271406 -0.180078422 -0.129856307 0.808576664 -1.84220885 FBgn0039698 CG7789 - http://flybase.org/reports/FBgn0039698 protein_coding_gene - "phosphatidylinositol phosphorylation ; GO:0046854 | inferred from electronic annotation with InterPro:IPR000760, InterPro:IPR020550" - CG7789 "IPR000760:Inositol monophosphatase-like, IPR020550:Inositol monophosphatase, conserved site, IPR020583:Inositol monophosphatase, metal-binding site" CG7789 27-Aug-18 DroID_v2018_08 "Drer\bpnt1, Drer\si:ch211-160o17.2" - Cele\bpnt-1 "Xtro\inpp1, Xtro\bpnt1" "Mmus\Inpp1, Mmus\Bpnt1" "Hsap\INPP1, Hsap\IMPAD1, Hsap\BPNT1" FBgn0053270 CG33270 - http://flybase.org/reports/FBgn0053270 protein_coding_gene molecular_function ; GO:0003674 | no biological data available lateral inhibition ; GO:0046331 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG6100, CG14139, CG32084, CG33270" - CG33270 27-Aug-18 DroID_v2018_08 - - - - - - "visible,partially lethal - majority die,some die during pupal stage" "chaeta,supernumerary,trichogen cell,mesothoracic tergum" DRSC10584 K 1.879979195 1.062089543 FBgn0058270 CG40270 - http://flybase.org/reports/FBgn0058270 protein_coding_gene - - - CG40270 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264676 lncRNA:CR43961 - http://flybase.org/reports/FBgn0264676 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG43961, CR43961" - CR43961 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266772 lncRNA:CR45237 - http://flybase.org/reports/FBgn0266772 non_protein_coding_gene - - - CR45237 - CR45237 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0028523 CG5888 - http://flybase.org/reports/FBgn0028523 protein_coding_gene - - - "BG:DS02780.1, CT18477, CG5888" "IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like, IPR001611:Leucine-rich repeat" CG5888 27-Aug-18 DroID_v2018_08 "Drer\lrit1b, Drer\LOC100330212, Drer\LOC101882074, Drer\lrit3b, Drer\lrit1a, Drer\lrrc53, Drer\lrit3a, Drer\si:dkey-52j6.3" - "Cele\egg-6, Cele\pan-1, Cele\lron-9" - "Mmus\Lrit1, Mmus\Tril, Mmus\Chadl, Mmus\Lrg1, Mmus\Lrrc26, Mmus\Lrrc52, Mmus\Cpn2, Mmus\Lgr5, Mmus\Lgr6, Mmus\Lrit3" "Hsap\LRIT3, Hsap\LRG1, Hsap\TRIL, Hsap\LGR5, Hsap\LRRC52, Hsap\LRRC26, Hsap\LRIT1, Hsap\CHADL, Hsap\CPN2, Hsap\LGR6" "viable,fertile" FBgn0051262 CG31262 - http://flybase.org/reports/FBgn0051262 protein_coding_gene transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR001734 transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR001734 "membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001734, InterPro:IPR019900" "CG31262, dSLC5A14" IPR001734:Sodium/solute symporter CG31262 27-Aug-18 DroID_v2018_08 "Drer\slc5a8, Drer\slc5a11, Drer\slc5a1, Drer\slc5a3a, Drer\slc5a9, Drer\LOC568338, Drer\si:dkeyp-9d4.5, Drer\slc5a6a, Drer\slc5a5, Drer\slc5a2, Drer\slc5a12, Drer\slc5a8l, Drer\slc5a6b" Scer\DUR3 "Cele\ZK822.5, Cele\F52H2.4" "Xtro\slc5a2, Xtro\slc5a5, Xtro\slc5a11, Xtro\slc5a12, Xtro\slc5a1.1, Xtro\slc5a8, Xtro\slc5a9" "Mmus\Slc5a1, Mmus\Slc5a5, Mmus\Slc5a6, Mmus\Slc5a3, Mmus\Slc5a4a, Mmus\Gm5134, Mmus\Slc5a2, Mmus\Slc5a11, Mmus\Slc5a10, Mmus\Slc5a8, Mmus\Slc5a12, Mmus\Slc5a9, Mmus\Slc5a4b" "Hsap\SLC5A8, Hsap\SLC5A3, Hsap\SLC5A10, Hsap\SLC5A5, Hsap\SLC5A6, Hsap\SLC5A1, Hsap\SLC5A9, Hsap\SLC5A4, Hsap\SLC5A12, Hsap\SLC5A2, Hsap\SLC5A11" DRSC13216 E -1.231515161 0.755300449 2.343924069 0.917808139 -0.487631205 -0.304477817 FBgn0034735 CG4610 - http://flybase.org/reports/FBgn0034735 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR023753 flavin adenine dinucleotide binding ; GO:0050660 | inferred from biological aspect of ancestor with PANTHER:PTN000211371 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR023753 mitochondrial tRNA wobble uridine modification ; GO:0070899 | inferred from biological aspect of ancestor with PANTHER:PTN000211372 tRNA methylation ; GO:0030488 | inferred from biological aspect of ancestor with PANTHER:PTN000211371 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000211372 CG4610 "IPR002218:tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related, IPR004416:tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, IPR020595:MnmG-related, conserved site, IPR026904:GidA associated domain 3, IPR023753:FAD/NAD(P)-binding domain" CG4610 27-Aug-18 DroID_v2018_08 Drer\mto1 Scer\MTO1 Cele\mtcu-2 - Mmus\Mto1 Hsap\MTO1 viable DRSC04477 K -0.943990332 0.139024208 -0.083137501 0.79969315 1.618695336 0.119877691 FBgn0010727 l(3)00720 lethal (3) 00720 http://flybase.org/reports/FBgn0010727 - gene - - - "P720, l(3)00720" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0031869 CG18304 - http://flybase.org/reports/FBgn0031869 protein_coding_gene - regulation of autophagy ; GO:0010506 | inferred from electronic annotation with InterPro:IPR027881 extracellular space ; GO:0005615 | inferred from electronic annotation with InterPro:IPR027881 "CG13774, CG18304" IPR027881:Protein SOGA CG18304 27-Aug-18 DroID_v2018_08 "Drer\soga3, Drer\soga1, Drer\si:ch211-197l9.2, Drer\mtcl1, Drer\soga3b" - Cele\tag-241 "Xtro\soga3, Xtro\soga1" "Mmus\Mtcl1, Mmus\Soga1, Mmus\Soga3" "Hsap\SOGA3, Hsap\SOGA1, Hsap\MTCL1" viable FBgn0033402 Myd88 Myd88 http://flybase.org/reports/FBgn0033402 protein_coding_gene "protein binding ; GO:0005515 | inferred from physical interaction with wek Toll binding ; GO:0005121 | inferred from physical interaction with Tl protein binding ; GO:0005515 | inferred from physical interaction with Fadd phosphatidylinositol-4,5-bisphosphate binding ; GO:0005546 | inferred from mutant phenotype" innate immune response ; GO:0045087 | non-traceable author statement dorsal/ventral pattern formation ; GO:0009953 | inferred from mutant phenotype positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype immune response ; GO:0006955 | traceable author statement Toll signaling pathway ; GO:0008063 | inferred from genetic interaction with tub inferred from genetic interaction with pll defense response to fungus ; GO:0050832 | inferred from mutant phenotype defense response to Gram-positive bacterium ; GO:0050830 | inferred from mutant phenotype positive regulation of antifungal peptide production ; GO:0002804 | inferred from direct assay response to fungus ; GO:0009620 | traceable author statement Toll signaling pathway ; GO:0008063 | traceable author statement antifungal peptide production ; GO:0002781 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay "dMyd88, Kra, MyD88, dMyD88, kra, DMMYD88, DmMyD88, CG2078, LD20892, EP(2)2535, DmMyd88, Myd88, myd88, MYD88, Myd88F, dMYd88" "IPR000157:Toll/interleukin-1 receptor homology (TIR) domain, IPR011029:Death-like domain" CG2078 27-Aug-18 DroID_v2018_08 Drer\myd88 - - Xtro\myd88 Mmus\Myd88 "Hsap\TIRAP, Hsap\MYD88, Hsap\SIGIRR" "immune response defective,recessive,female sterile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,female fertile,viable,lethal,dorsal/ventral axis specification defective,germline clone,non-rescuable maternal effect" "filzkorper,denticle belt,embryonic epidermis,ventral" FBgn0024993 CG2662 - http://flybase.org/reports/FBgn0024993 - protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001965 - - "EG:100G10.6, CG2662, snuts, MAD" "IPR001660:Sterile alpha motif domain, IPR001965:Zinc finger, PHD-type, IPR013761:Sterile alpha motif/pointed domain, IPR019786:Zinc finger, PHD-type, conserved site, IPR019787:Zinc finger, PHD-finger, IPR011011:Zinc finger, FYVE/PHD-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG2662 27-Aug-18 DroID_v2018_08 "Drer\samd1a, Drer\samd1b, Drer\samd13" Scer\SFP1 "Cele\mys-4, Cele\dpff-1" Xtro\samd13 "Mmus\4930503B20Rik, Mmus\Samd1, Mmus\Dpf2" "Hsap\SAMD13, Hsap\SAMD1, Hsap\DPF2, Hsap\THAP10" viable DRSC18468 IK 2.18349238 1.75573769 1.082161342 0.172355973 1.689209517 0.294458768 FBgn0267154 lncRNA:CR45594 - http://flybase.org/reports/FBgn0267154 non_protein_coding_gene - - - CR45594 - CR45594 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037429 Osi19 Osiris 19 http://flybase.org/reports/FBgn0037429 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available integral component of plasma membrane ; GO:0005887 | inferred from sequence model "Osi19, CG15189" IPR012464:Protein of unknown function DUF1676 CG15189 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0029161 slmo slowmo http://flybase.org/reports/FBgn0029161 protein_coding_gene - germarium-derived oocyte differentiation ; GO:0030706 | inferred from mutant phenotype peristalsis ; GO:0030432 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype larval locomotory behavior ; GO:0008345 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from mutant phenotype "CT26166, kisir, CG9131, slmo" IPR006797:PRELI/MSF1 domain CG9131 27-Aug-18 DroID_v2018_08 "Drer\prelid3b, Drer\prelid3a" "Scer\UPS3, Scer\UPS2" Cele\F15D3.6 "Xtro\prelid3a, Xtro\prelid2" "Mmus\Prelid2, Mmus\Slmo1, Mmus\Slmo2" "Hsap\PRELID3A, Hsap\PRELID3B, Hsap\PRELID2" "viable,male sterile,recessive,locomotor behavior defective,lethal - all die before end of larval stage,some die during larval stage,lethal,flight defective,visible" "wing,trichogen cell,mesothoracic tergum" DRSC03143 IEK -1.518622585 -1.072497697 -0.957496416 -2.747169355 1.595478521 0.490373303 FBgn0033154 CG1850 - http://flybase.org/reports/FBgn0033154 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG1850 - CG1850 27-Aug-18 DroID_v2018_08 "Drer\zgc:162964, Drer\acbd3, Drer\tmed8" - Cele\Y41E3.7 - "Mmus\Tmed8, Mmus\Acbd3" "Hsap\TMED8, Hsap\ACBD3" viable FBgn0010062 M(2)34d M(2)34d http://flybase.org/reports/FBgn0010062 - gene - - - M(2)34d - - 27-Aug-18 DroID_v2018_08 - - - - - - visible eye FBgn0065512 l(2)SH1166 lethal (2) SH1166 http://flybase.org/reports/FBgn0065512 gene - - - l(2)SH1166 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0005038 Est-A Esterase A http://flybase.org/reports/FBgn0005038 - gene - - - "Est18, Est-A" - - 27-Aug-18 DroID_v2018_08 - - - - - - electrophoretic variant FBgn0085762 CG40648 - http://flybase.org/reports/FBgn0085762 protein_coding_gene - - - "CG40648, CR40648" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267875 CR46163 - http://flybase.org/reports/FBgn0267875 pseudogene_attribute - - - CR46163 - CR46163 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031947 CG7154 - http://flybase.org/reports/FBgn0031947 protein_coding_gene - neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype - "CG7154, BRD7" "IPR001487:Bromodomain, IPR021900:Protein of unknown function DUF3512" CG7154 27-Aug-18 DroID_v2018_08 "Drer\brd9, Drer\brd7" - Cele\swsn-9 "Xtro\brd9, Xtro\brd7" "Mmus\Brd9, Mmus\Brd7" "Hsap\BRD9, Hsap\BRD7" "visible,partially lethal - majority die,some die during pupal stage" mesothoracic tergum DRSC03017 E -0.697418664 0.719613499 0.226420442 -1.509175214 -0.521056247 1.062154707 FBgn0039038 CG6688 - http://flybase.org/reports/FBgn0039038 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 multicellular organism development ; GO:0007275 | inferred from electronic annotation with InterPro:IPR004162 ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from electronic annotation with InterPro:IPR004162 nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR004162 CG6688 "IPR001478:PDZ domain, IPR001841:Zinc finger, RING-type, IPR004162:E3 ubiquitin-protein ligase SIN-like, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG6688 27-Aug-18 DroID_v2018_08 "Drer\cyhr1, Drer\grip2b, Drer\il16, Drer\dlg5a, Drer\grip1, Drer\slc9a3r1, Drer\grid2ipa, Drer\siah2l, Drer\lnx1, Drer\pdzd7b, Drer\si:dkey-92i15.4, Drer\pard3bb, Drer\siah1, Drer\inadl" - Cele\siah-1 "Xtro\grip2, Xtro\siah1, Xtro\dlg5, Xtro\siah2, Xtro\lnx1, Xtro\grid2ip, Xtro\grip1" "Mmus\Mpdz, Mmus\Pdzd11, Mmus\Ush1c, Mmus\Grip1, Mmus\Pdzd2, Mmus\Patj, Mmus\Siah1a, Mmus\Grasp, Mmus\6330408A02Rik, Mmus\Cyhr1, Mmus\Slc9a3r2, Mmus\Il16, Mmus\Grid2ip, Mmus\Siah3, Mmus\Grip2, Mmus\Siah1b, Mmus\Lnx1, Mmus\Pdzph1, Mmus\Siah2, Mmus\Dlg5" "Hsap\GRID2IP, Hsap\SIAH3, Hsap\FRMPD2, Hsap\C19orf68, Hsap\PARD3B, Hsap\IL16, Hsap\PATJ, Hsap\SLC9A3R2, Hsap\USH1C, Hsap\CYHR1, Hsap\PDZD2, Hsap\GRASP, Hsap\MPDZ, Hsap\SIAH2, Hsap\LNX1, Hsap\SIAH1, Hsap\GRIP1, Hsap\DLG5" "viable,fertile" FBgn0065073 snoRNA:229 snoRNA:229 http://flybase.org/reports/FBgn0065073 snoRNA_gene - - - "Dm-229, snoR229, CR33684, snoRNA:229, DmOr_cd3, SnoR229, chr2R:18581419..18581570" - CR33684 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0029898 CG14439 - http://flybase.org/reports/FBgn0029898 protein_coding_gene - transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011701 CG14439 "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG14439 27-Aug-18 DroID_v2018_08 "Drer\spns2, Drer\spns3, Drer\spns1" - - Xtro\spns1 "Mmus\Spns1, Mmus\Spns3, Mmus\Spns2" "Hsap\SPNS1, Hsap\SPNS2, Hsap\SPNS3" "viable,fertile" FBgn0069416 JJF144 JJF144 http://flybase.org/reports/FBgn0069416 gene - - - JJF144 - - 27-Aug-18 DroID_v2018_08 - - - - - - stress response defective FBgn0260005 wtrw water witch http://flybase.org/reports/FBgn0260005 protein_coding_gene cation channel activity ; GO:0005261 | inferred from sequence or structural similarity with pyx calcium channel activity ; GO:0005262 | inferred from sequence or structural similarity transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005821 sensory perception of sound ; GO:0007605 | inferred from mutant phenotype cation transport ; GO:0006812 | inferred from sequence or structural similarity with pyx calcium ion transport ; GO:0006816 | inferred from sequence or structural similarity response to humidity ; GO:0009270 | inferred from mutant phenotype cation channel complex ; GO:0034703 | inferred from sequence or structural similarity with pyx "CG17817, wtrw, CG31284, 153412_at, CT29234, CG10409, Wtrw, dTRPA3, trpA3" "IPR002110:Ankyrin repeat, IPR005821:Ion transport domain, IPR020683:Ankyrin repeat-containing domain" CG31284 27-Aug-18 DroID_v2018_08 "Drer\trpa1a, Drer\trpa1b" - "Cele\osm-9, Cele\trpa-1" Xtro\trpa1 "Mmus\Trpv1, Mmus\Trpa1" "Hsap\TRPA1, Hsap\TRPV1" FBgn0051952 CG31952 - http://flybase.org/reports/FBgn0051952 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG15413, BcDNA:AT14709, CG31952" - CG31952 27-Aug-18 DroID_v2018_08 - - - - Mmus\Basp1 - "viable,visible" "chaeta,supernumerary" DRSC21997 IK -1.550360148 0.05717731 -1.285798533 -1.056348261 0.418455833 1.683162186 FBgn0061005 l(3)S026437 lethal (3) S026437 http://flybase.org/reports/FBgn0061005 gene - - - "0264/37, l(3)S026437" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0266145 lncRNA:CR44851 - http://flybase.org/reports/FBgn0266145 non_protein_coding_gene - - - CR44851 - CR44851 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000853 fs(1)M43 female sterile (1) M43 http://flybase.org/reports/FBgn0000853 - gene - - - fs(1)M43 - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive,lethal,lethal - all die before end of embryonic stage,maternal effect,heat sensitive,some die during embryonic stage" "egg,maternal effect" FBgn0032303 CG6508 - http://flybase.org/reports/FBgn0032303 protein_coding_gene aspartic-type endopeptidase activity ; GO:0004190 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 protein catabolic process ; GO:0030163 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 proteolysis ; GO:0006508 | inferred from biological aspect of ancestor with PANTHER:PTN000342793 - CG6508 "IPR001461:Aspartic peptidase A1 family, IPR001969:Aspartic peptidase, active site, IPR021109:Aspartic peptidase domain, IPR033121:Peptidase family A1 domain" CG6508 27-Aug-18 DroID_v2018_08 "Drer\zgc:103530, Drer\ren, Drer\nots, Drer\ctsd, Drer\zgc:63831" "Scer\MKC7, Scer\YGL258W-A, Scer\YPS6, Scer\YPS5, Scer\YPS1, Scer\YPS3, Scer\BAR1, Scer\YPS7, Scer\PEP4" "Cele\asp-10, Cele\asp-17, Cele\asp-13, Cele\asp-9, Cele\asp-8, Cele\asp-4, Cele\asp-2, Cele\asp-6, Cele\asp-15, Cele\asp-7, Cele\asp-16, Cele\asp-18, Cele\asp-19, Cele\asp-5, Cele\asp-3, Cele\asp-12, Cele\asp-1" "Xtro\pgc, Xtro\ctse, Xtro\pga4, Xtro\ctsd, Xtro\ren, Xtro\bace1, Xtro\napsa, Xtro\LOC496913, Xtro\bace2" "Mmus\Pgc, Mmus\Ren1, Mmus\Napsa, Mmus\Ctse, Mmus\Cym, Mmus\Ctsd, Mmus\Pga5, Mmus\Bace1, Mmus\Bace2" "Hsap\BACE1, Hsap\PGA3, Hsap\CTSE, Hsap\CTSD, Hsap\PGA5, Hsap\PGC, Hsap\BACE2, Hsap\PGA4, Hsap\NAPSA, Hsap\REN" viable FBgn0010774 Ref1 RNA and export factor binding protein 1 http://flybase.org/reports/FBgn0010774 FBgn0027857 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity transcription coactivator activity ; GO:0003713 | inferred from sequence or structural similarity "mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013" nucleoplasm ; GO:0005654 | inferred from direct assay precatalytic spliceosome ; GO:0071011 | inferred from direct assay transcription export complex ; GO:0000346 | inferred from sequence or structural similarity with HGNC:19071 nucleus ; GO:0005634 | inferred from direct assay nuclear membrane ; GO:0031965 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay "ref1, REF1, CG1101, dmREF1, DmREF1, cg1101, l(3)02267, BcDNA:LD24793, Aly, ALY, Ref1, aly" "IPR025715:Chromatin target of PRMT1 protein, C-terminal, IPR000504:RNA recognition motif domain" CG1101 27-Aug-18 DroID_v2018_08 "Drer\poldip3, Drer\alyref" Scer\YRA1 "Cele\C02B10.4, Cele\Y37E11AL.9, Cele\aly-1, Cele\aly-2, Cele\R06C1.4, Cele\aly-3" "Xtro\poldip3, Xtro\alyref" "Mmus\Alyref2, Mmus\Gm4307, Mmus\Gm4305, Mmus\Gm21312, Mmus\Gm6763, Mmus\Gm4312, Mmus\Gm20765, Mmus\Gm4303, Mmus\Gm4302, Mmus\Gm21293, Mmus\Poldip3, Mmus\Alyref, Mmus\Gm8764, Mmus\Gm4340, Mmus\Gm21304, Mmus\Gm4301" "Hsap\ALYREF, Hsap\POLDIP3, Hsap\CSTF2T"

"lethal,recessive,viable,visible,planar polarity defective,female semi-sterile,female fertile" "trichogen cell,supernumerary" DRSC22387 IE 2.800958662 1.499724054 7.369790215 4.863691565 0.035585267 -0.082481817 FBgn0259830 ifm(2)RS14 indirect flight muscle (2) RS14 http://flybase.org/reports/FBgn0259830 gene - adult somatic muscle development ; GO:0007527 | inferred from mutant phenotype - ifm(2)RS14 - - 27-Aug-18 DroID_v2018_08 - - - - - - viable indirect flight muscle FBgn0001711 l(1)ESHS32 lethal (1) ESHS32 http://flybase.org/reports/FBgn0001711 - gene - - - l(1)ESHS32 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0064193 arbl arborless http://flybase.org/reports/FBgn0064193 gene - - - arbl - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085486 CG34457 - http://flybase.org/reports/FBgn0085486 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG34457, CG5197, SP118" - CG34457 27-Aug-18 DroID_v2018_08 Drer\cfap161 - - Xtro\cfap161 Mmus\Cfap161 Hsap\CFAP161 FBgn0259839 Su(Ste):CR42408 Su(Ste):CR42408 http://flybase.org/reports/FBgn0259839 non_protein_coding_gene - - - "Su(Ste):CR42408, CR42408" - CR42408 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033354 FANCI Fanconi anemia complementation group I http://flybase.org/reports/FBgn0033354 protein_coding_gene DNA polymerase binding ; GO:0070182 | inferred from biological aspect of ancestor with PANTHER:PTN000497925 DNA repair ; GO:0006281 | inferred from electronic annotation with InterPro:IPR026171 mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs - "CG13745, FANCI, fanci" "IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical, IPR029314:FANCI solenoid 4 domain, IPR029315:FANCI solenoid 2 domain, IPR029313:FANCI solenoid 3 domain, IPR029308:FANCI solenoid 1 domain, IPR029312:FANCI helical domain 2, IPR026171:Fanconi anemia group I protein" CG13745 27-Aug-18 DroID_v2018_08 Drer\fanci - Cele\fnci-1 Xtro\polg Mmus\Fanci Hsap\FANCI viable FBgn0034803 CG9849 - http://flybase.org/reports/FBgn0034803 protein_coding_gene - muscle cell fate determination ; GO:0007521 | inferred from mutant phenotype extracellular region ; GO:0005576 | inferred from sequence or structural similarity with UniProtKB:Q9BSG0 CG9849 IPR003137:PA domain CG9849 27-Aug-18 DroID_v2018_08 - - "Cele\ZC506.1, Cele\T07F12.2" Xtro\pradc1 Mmus\Pradc1 Hsap\PRADC1 viable embryonic/larval salivary gland FBgn0051752 CG31752 - http://flybase.org/reports/FBgn0051752 protein_coding_gene - - - "CG10599, CG31752" - CG31752 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC22599 K -0.315661475 0.552585453 0.027950964 -0.70852202 2.693544161 -0.079404907 FBgn0023496 Lip1 Lipase 1 http://flybase.org/reports/FBgn0023496 - protein_coding_gene "hydrolase activity, acting on ester bonds ; GO:0016788 | inferred from electronic annotation with InterPro:IPR025483" lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR006693 digestion ; GO:0007586 | inferred from expression pattern extracellular region ; GO:0005576 | non-traceable author statement "CG7279, lip1, Dmlip1, Lip1, dLip1, Lip, LIP1Dm, dilp1" "IPR025483:Lipase, eukaryotic, IPR006693:Partial AB-hydrolase lipase domain, IPR029058:Alpha/Beta hydrolase fold" CG7279 27-Aug-18 DroID_v2018_08 Drer\lipf "Scer\YEH2, Scer\YEH1, Scer\TGL1" "Cele\lipl-5, Cele\lipl-6, Cele\lipl-1, Cele\lipl-2, Cele\lipl-3, Cele\lipl-7, Cele\lipl-4, Cele\lipl-8" Xtro\lipa "Mmus\Lipo4, Mmus\Lipa, Mmus\Lipf, Mmus\Lipo2, Mmus\Lipm, Mmus\Lipk, Mmus\Lipn, Mmus\Lipo3, Mmus\Lipo1" "Hsap\LIPN, Hsap\LIPJ, Hsap\LIPK, Hsap\LIPF, Hsap\LIPA, Hsap\LIPM" " adult stage | female , larval stage && pupal stage , adult stage | male , embryonic stage | late , embryonic stage | stage >=14 " " embryonic/larval pharynx

, embryonic/larval proventriculus

" "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0262485 CG43075 - http://flybase.org/reports/FBgn0262485 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43075 - CG43075 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0043967 U5E3sis U5E3sis http://flybase.org/reports/FBgn0043967 gene - - - U5E3sis - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0027629 ms(1)RA20 ms(1)RA20 http://flybase.org/reports/FBgn0027629 - gene - - - ms(1)RA20 - - 27-Aug-18 DroID_v2018_08 - - - - - - male sterile spermatocyte FBgn0266770 CR45235 - http://flybase.org/reports/FBgn0266770 non_protein_coding_gene - - - CR45235 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0261987 Pxt Peroxinectin-like http://flybase.org/reports/FBgn0261987 protein_coding_gene heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR010255 peroxidase activity ; GO:0004601 | inferred from sequence or structural similarity with UniProtKB:P82600 peroxidase activity ; GO:0004601 | inferred from biological aspect of ancestor with PANTHER:PTN000158755 prostaglandin-endoperoxide synthase activity ; GO:0004666 | inferred from sequence model oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR010255 response to oxidative stress ; GO:0006979 | inferred from electronic annotation with InterPro:IPR010255 eggshell chorion assembly ; GO:0007306 | inferred from sequence or structural similarity with UniProtKB:P82600 chorion-containing eggshell formation ; GO:0007304 | inferred from mutant phenotype hydrogen peroxide metabolic process ; GO:0042743 | inferred from sequence or structural similarity with UniProtKB:P82600 ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype prostaglandin biosynthetic process ; GO:0001516 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay "pxt, Pxt, Dpxt, CG7660, anon-WO0172774.128, pxd" "IPR029590:Chorion peroxidase, IPR010255:Haem peroxidase, IPR019791:Haem peroxidase, animal" CG7660 27-Aug-18 DroID_v2018_08 "Drer\ptgs1, Drer\tpo, Drer\igsf9bb, Drer\ptgs2b, Drer\ptgs2a" - "Cele\pxn-1, Cele\C46A5.4, Cele\T06D8.10, Cele\K10B4.1, Cele\skpo-3, Cele\mlt-7" "Xtro\ptgs1, Xtro\pxdn, Xtro\ptgs2, Xtro\epx, Xtro\mpo, Xtro\tpo" "Mmus\Lpo, Mmus\Mpo, Mmus\Pxdn, Mmus\Ptgs2, Mmus\Ptgs1, Mmus\Tpo, Mmus\Epx" "Hsap\LPO, Hsap\PTGS2, Hsap\PTGS1, Hsap\PXDNL, Hsap\PXDN, Hsap\MPO, Hsap\EPX, Hsap\TPO" FBgn0085489 CG34460 - http://flybase.org/reports/FBgn0085489 protein_coding_gene molecular_function ; GO:0003674 | no biological data available imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype extracellular space ; GO:0005615 | inferred from sequence model "CG34460, bs26g12.y1, CG6301, bs26g12" IPR029277:Single domain Von Willebrand factor type C domain CG34460 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051506 tRNA:Leu-TAA-1-1 transfer RNA:Leucine-TAA 1-1 http://flybase.org/reports/FBgn0051506 tRNA_gene UUA codon-amino acid adaptor activity ; GO:0033403 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033403 cytosol ; GO:0005829 | inferred by curator from GO:0033403 "AE002708.trna40-LeuTAA, tRNA:L:TAA:AE002708-c, CR31506, chr3R.trna46-LeuTAA, tRNA-Leu-TAA-1-1, tRNA:Leu-TAA-1-1, tRNA:CR31506, UUA" - CR31506 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263513 mir-4953 mir-4953 stem loop http://flybase.org/reports/FBgn0263513 miRNA_gene - - - "mir-4953, CR43616, dme-mir-4953" - CR43616 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265345 lncRNA:CR44299 - http://flybase.org/reports/FBgn0265345 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG44299, CR44299" - CR44299 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265364 lncRNA:CR44305 - http://flybase.org/reports/FBgn0265364 non_protein_coding_gene - - - CR44305 - CR44305 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0082359 HM165 HM165 http://flybase.org/reports/FBgn0082359 gene - - - HM165 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0066114 GlcAT-I GlcAT-I http://flybase.org/reports/FBgn0066114 protein_coding_gene galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity ; GO:0015018 | inferred from direct assay glucuronosyltransferase activity ; GO:0015020 | non-traceable author statement carbohydrate metabolic process ; GO:0005975 | inferred from biological aspect of ancestor with PANTHER:PTN000096174 chondroitin sulfate biosynthetic process ; GO:0030206 | non-traceable author statement proteoglycan biosynthetic process ; GO:0030166 | non-traceable author statement heparan sulfate proteoglycan biosynthetic process ; GO:0015012 | non-traceable author statement chondroitin sulfate metabolic process ; GO:0030204 | inferred from biological aspect of ancestor with PANTHER:PTN000855563 chondroitin sulfate proteoglycan biosynthetic process ; GO:0050650 | inferred from biological aspect of ancestor with PANTHER:PTN000855563 membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR005027 "DmGlcAT-I, CAA21824, DGlcAT-I, RE38067, EG:EG0007.5, CG32775, BcDNA:GH05057, GlcAT-I, GlcAT1, GH05057p, dGlcAT-I" "IPR005027:Glycosyl transferase, family 43, IPR029044:Nucleotide-diphospho-sugar transferases" CG32775 27-Aug-18 DroID_v2018_08 "Drer\b3gat1b, Drer\b3gat2, Drer\b3gat1a, Drer\b3gat3" - "Cele\glct-3, Cele\glct-1, Cele\glct-4, Cele\sqv-8, Cele\glct-6, Cele\glct-2, Cele\glct-5" "Xtro\b3gat1, Xtro\b3gat3, Xtro\b3gat2" "Mmus\B3gat1, Mmus\B3gat3, Mmus\B3gat2" "Hsap\B3GAT2, Hsap\B3GAT3, Hsap\B3GAT1" embryonic stage -- adult stage "viable,fertile" FBgn0060584 l(3)S094405b lethal (3) S094405b http://flybase.org/reports/FBgn0060584 gene - - - "0944/05, l(3)S094405b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0010821 l(3)03847 lethal (3) 03847 http://flybase.org/reports/FBgn0010821 - gene - - - l(3)03847 - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0011959 tRNA:Arg-ACG-1-10 transfer RNA:Arginine-ACG 1-10 http://flybase.org/reports/FBgn0011959 "FBgn0003758, FBgn0011947, FBgn0051581, FBgn0060097" tRNA_gene CGU codon-amino acid adaptor activity ; GO:0033429 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033429 cytosol ; GO:0005829 | inferred by curator from GO:0033429 "tRNA[arg], tRNA[Arg][[2]], AE002708.trna62-ArgACG, tRNA:R1, tRNA:arg1, tRNA:R:ACG:AE002708-a, CR31581, tRNA:arg2:84Fa, chr3R.trna68-ArgACG, tRNA-Arg-ACG-1-10, tRNA:Arg-ACG-1-10, tRNA:R2:84Fa, CGU" - CR31581 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002002 l(2)36Ba lethal (2) 36Ba http://flybase.org/reports/FBgn0002002 FBgn0010489 gene - - - "l(2)HT-4, l(2L)HT-4, l(2)01433, l(2)36Ba" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0053370 5SrRNA:CR33370 5SrRNA:CR33370 http://flybase.org/reports/FBgn0053370 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33370, 5SrRNA:CR33370" - CR33370 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030718 ND-20 NADH dehydrogenase (ubiquinone) 20 kDa subunit http://flybase.org/reports/FBgn0030718 protein_coding_gene "NADH dehydrogenase (ubiquinone) activity ; GO:0008137 | inferred from electronic annotation with InterPro:IPR006138 4 iron, 4 sulfur cluster binding ; GO:0051539 | inferred from electronic annotation with InterPro:IPR006138 quinone binding ; GO:0048038 | inferred from electronic annotation with InterPro:IPR006138 NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:O75251" "mitochondrial respiratory chain complex I assembly ; GO:0032981 | inferred from mutant phenotype regulation of terminal button organization ; GO:2000331 | inferred from mutant phenotype mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with UniProtKB:O75251 determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype response to reactive oxygen species ; GO:0000302 | inferred from mutant phenotype" mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:O75251 "CG9172, 20 kDa, NUKM, ND-20, Dmel_CG9172, PSST" "IPR006137:NADH:ubiquinone oxidoreductase-like, 20kDa subunit, IPR006138:NADH-ubiquinone oxidoreductase, 20 Kd subunit" CG9172 27-Aug-18 DroID_v2018_08 Drer\ndufs7 - Cele\nduf-7 Xtro\ndufs7 Mmus\Ndufs7 Hsap\NDUFS7 "lethal - all die before end of larval stage,some die during larval stage,long lived,female,RU486 conditional,female semi-fertile,stress response defective,viable,visible" "trichogen cell,mesothoracic tergum,adult heart,RU486 conditional" FBgn0020280 laf labial associated factor http://flybase.org/reports/FBgn0020280 "FBgn0015605, FBgn0037285" protein_coding_gene molecular_function ; GO:0003674 | no biological data available - - "C6, CG14660, laf" - CG14660 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0001847 l(1)ts3803 lethal (1) ts3803 http://flybase.org/reports/FBgn0001847 - gene - - - l(1)ts3803 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,heat sensitive,female sterile" FBgn0045053 fs(1)221a female sterile (1) 221a http://flybase.org/reports/FBgn0045053 gene molecular_function ; GO:0003674 | no biological data available oogenesis ; GO:0048477 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available fs(1)221a - - 27-Aug-18 DroID_v2018_08 - - - - - - female sterile "nurse cell & nucleus,nurse cell,follicle cell,border follicle cell" FBgn0260756 CG42554 - http://flybase.org/reports/FBgn0260756 protein_coding_gene molecular_function ; GO:0003674 | no biological data available neurogenesis ; GO:0022008 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG13886, CT33419, CG42554" - CG42554 27-Aug-18 DroID_v2018_08 "Drer\nrbf2b, Drer\nrbf2a, Drer\zgc:55781" - - Xtro\c7orf25 "Mmus\AW209491, Mmus\Nrbf2" "Hsap\C7orf25, Hsap\NRBF2" "lethal,neuroanatomy defective,viable,visible" "ganglion mother cell,mesothoracic tergum" FBgn0004991 chy chunky http://flybase.org/reports/FBgn0004991 - gene - - - chy - - 27-Aug-18 DroID_v2018_08 - - - - - - "wing,adult abdomen" FBgn0010930 l(3)08724 lethal (3) 08724 http://flybase.org/reports/FBgn0010930 - gene - - - l(3)08724 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0083080 luke lucky luke http://flybase.org/reports/FBgn0083080 gene - - - luke - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0069958 CG41059 - http://flybase.org/reports/FBgn0069958 protein_coding_gene - - - CG41059 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051820 CG31820 - http://flybase.org/reports/FBgn0051820 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs36g10, NEST:bs10d03, CG31820" - CG31820 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0004032 wz wizened http://flybase.org/reports/FBgn0004032 - gene - - - wz - - 27-Aug-18 DroID_v2018_08 - - - - - - "sterile,recessive,visible,body color defective" macrochaeta FBgn0044040 Masc29a Masc29a http://flybase.org/reports/FBgn0044040 gene - - - Masc29a - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051862 CG31862 - http://flybase.org/reports/FBgn0051862 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG31862 - CG31862 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0053648 CG33648 - http://flybase.org/reports/FBgn0053648 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG33648 IPR010512:Protein of unknown function DUF1091 CG33648 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263331 lncRNA:CR43412 - http://flybase.org/reports/FBgn0263331 non_protein_coding_gene - - - CR43412 - CR43412 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0086611 Lcp65Ag3 Larval cuticle protein http://flybase.org/reports/FBgn0086611 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Lcp65Ag3, Lcp-g3, g3, CG18779, DmelLcp65Ag3" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG18779 27-Aug-18 DroID_v2018_08 Drer\LOC100003040 - "Cele\math-34, Cele\sdz-30, Cele\F44F1.4" - "Mmus\2410137M14Rik, Mmus\H2-K1" - " larval stage , embryonic stage , pupal stage | 7-13 hr " FBgn0030582 CG14411 - http://flybase.org/reports/FBgn0030582 protein_coding_gene protein tyrosine phosphatase activity ; GO:0004725 | NOT inferred from sequence model phosphatidylinositol-3-phosphatase activity ; GO:0004438 | inferred from sequence or structural similarity with SGD:S000003871 phosphatidylinositol dephosphorylation ; GO:0046856 | inferred from sequence or structural similarity with SGD:S000003871 defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000003871 CG14411 "IPR030564:Myotubularin family, IPR011993:PH domain-like, IPR029021:Protein-tyrosine phosphatase-like, IPR010569:Myotubularin-like phosphatase domain, IPR022587:Myotubularin-related 12-like C-terminal domain" CG14411 27-Aug-18 DroID_v2018_08 "Drer\mtmr8, Drer\sbf1, Drer\mtmr2, Drer\mtmr6, Drer\mtmr12, Drer\zgc:154055, Drer\mtmr11, Drer\mtmr7a, Drer\sbf2, Drer\mtmr7b, Drer\mtmr1b, Drer\mtmr10, Drer\mtmr9, Drer\mtmr1a" Scer\YMR1 "Cele\mtm-5, Cele\mtm-3, Cele\mtm-1, Cele\Y48G1C.10" "Xtro\mtmr10, Xtro\mtmr6, Xtro\mtm1, Xtro\mtmr1, Xtro\asb12.2, Xtro\mtmr2, Xtro\mtmr7, Xtro\mtmr12, Xtro\LOC100216114, Xtro\mtmr9" "Mmus\Mtm1, Mmus\Sbf2, Mmus\Mtmr2, Mmus\Mtmr12, Mmus\Mtmr7, Mmus\Mtmr1, Mmus\Mtmr10, Mmus\Mtmr6, Mmus\Mtmr9, Mmus\Mtmr11, Mmus\Sbf1" "Hsap\MTMR1, Hsap\MTM1, Hsap\SBF2, Hsap\MTMR9, Hsap\MTMR10, Hsap\MTMR7, Hsap\SBF1, Hsap\MTMR2, Hsap\MTMR6, Hsap\MTMR8, Hsap\MTMR11, Hsap\MTMR12" viable FBgn0023202 Hci Hci http://flybase.org/reports/FBgn0023202 - gene - - - "DHCI, Hci" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0028229 l(3)S004624 lethal (3) S004624 http://flybase.org/reports/FBgn0028229 gene - - - "0245/33, 0475/22, l(3)S024533a, l(3)S047522, l(3)S004624" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0264276 Su(Mir)2 - http://flybase.org/reports/FBgn0264276 gene - - - Su(Mir)2 - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,female sterile,lethal" FBgn0267775 lncRNA:CR46106 - http://flybase.org/reports/FBgn0267775 non_protein_coding_gene - - - CR46106 - CR46106 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0069106 mus318 mutagen-sensitive 318 http://flybase.org/reports/FBgn0069106 gene - - - mus318 - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,chemical sensitive" FBgn0060570 l(3)S096003b lethal (3) S096003b http://flybase.org/reports/FBgn0060570 gene - - - "0960/03, l(3)S096003b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0065352 l(2)SH1797 lethal (2) SH1797 http://flybase.org/reports/FBgn0065352 gene - - - "l(2)SH1797, l(2)SH2 1797" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0036390 CG13738 - http://flybase.org/reports/FBgn0036390 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:RE61257, CG13738" - CG13738 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile,lethal - all die before end of pupal stage,some die during pupal stage" DRSC10065 IE 0.413682796 -2.651382887 0.34192245 -1.669579992 -0.781042733 0.202180698 FBgn0263968 nonC no-on-and-no-off transient C http://flybase.org/reports/FBgn0263968 protein_coding_gene protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with UniProtKB:Q96Q15 protein kinase activity ; GO:0004672 | non-traceable author statement "nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ; GO:0000184 | inferred from mutant phenotype nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ; GO:0000184 | inferred from direct assay RNA interference ; GO:0016246 | NOT inferred from mutant phenotype protein autophosphorylation ; GO:0046777 | inferred from sequence or structural similarity with UniProtKB:Q96Q15 gene silencing by miRNA ; GO:0035195 | NOT inferred from mutant phenotype response to stress ; GO:0006950 | inferred from sequence or structural similarity with UniProtKB:Q96Q15 phosphorylation ; GO:0016310 | non-traceable author statement nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ; GO:0000184 | NOT inferred from mutant phenotype neuromuscular synaptic transmission ; GO:0007274 | inferred from direct assay synapse organization ; GO:0050808 | inferred from direct assay synaptic vesicle transport ; GO:0048489 | inferred from direct assay peptidyl-serine phosphorylation ; GO:0018105 | inferred from sequence or structural similarity with UniProtKB:Q96Q15" nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q96Q15 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:Q96Q15 "nonC, smg1, CG32743, rst(1a)cyr, CG4555, CG4549, SMG1, clone 1.24, anon-EST:Liang-1.24, anon-WO0170980.133, Smg1, Smg, dSmg1" "IPR000403:Phosphatidylinositol 3-/4-kinase, catalytic domain, IPR003152:FATC domain, IPR011009:Protein kinase-like domain, IPR014009:PIK-related kinase, IPR016024:Armadillo-type fold, IPR011989:Armadillo-like helical, IPR031559:Serine/threonine-protein kinase SMG1" CG32743 27-Aug-18 DroID_v2018_08 "Drer\smg1, Drer\prkdc" "Scer\TOR1, Scer\TOR2" Cele\smg-1 "Xtro\mtor, Xtro\smg1, Xtro\prkdc" "Mmus\Prkdc, Mmus\Smg1, Mmus\Mtor" "Hsap\BOLA2-SMG1P6, Hsap\BOLA2B, Hsap\BOLA2, Hsap\PRKDC, Hsap\MTOR, Hsap\SMG1" FBgn0061512 frogger\polyprotein frogger element polyprotein http://flybase.org/reports/FBgn0061512 transposable_element_gene - - - frogger\polyprotein "IPR013103:Reverse transcriptase, RNA-dependent DNA polymerase" - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0042110 CG18765 - http://flybase.org/reports/FBgn0042110 protein_coding_gene - - - CG18765 "IPR015897:CHK kinase-like, IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain" CG18765 27-Aug-18 DroID_v2018_08 Drer\LOC100150280 - "Cele\F59B1.10, Cele\F59B1.8, Cele\nhr-246, Cele\C29F7.2" - - - viable FBgn0086038 snoRNA:Me28S-C1237 - http://flybase.org/reports/FBgn0086038 snoRNA_gene - - - "snoRNA:Me28S-C1237, Me28S-Cm1237, CR34667" - CR34667 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259848 Su(Ste):CR42417 Su(Ste):CR42417 http://flybase.org/reports/FBgn0259848 non_protein_coding_gene - - - "Su(Ste):CR42417, CR42417" - CR42417 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0029050 l(1)G0462 lethal (1) G0462 http://flybase.org/reports/FBgn0029050 gene - - - l(1)G0462 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0083976 CG34140 - http://flybase.org/reports/FBgn0083976 protein_coding_gene "RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR001406, InterPro:IPR020094, InterPro:IPR020095, InterPro:IPR020097, InterPro:IPR020103 pseudouridine synthase activity ; GO:0009982 | inferred from biological aspect of ancestor with PANTHER:PTN000124732" tRNA pseudouridine synthesis ; GO:0031119 | inferred from biological aspect of ancestor with PANTHER:PTN000124732 cellular_component ; GO:0005575 | no biological data available "CG7042, CG34140" "IPR020097:Pseudouridine synthase I, TruA, alpha/beta domain, IPR020103:Pseudouridine synthase, catalytic domain, IPR020095:Pseudouridine synthase I, TruA, C-terminal, IPR001406:Pseudouridine synthase I, TruA" CG34140 27-Aug-18 DroID_v2018_08 "Drer\pusl1, Drer\pus3" Scer\DEG1 "Cele\tag-124, Cele\Y73B6BL.29" Xtro\pusl1 "Mmus\Pus3, Mmus\Pusl1" "Hsap\PUSL1, Hsap\PUS3" "viable,fertile" FBgn0034363 CG5327 - http://flybase.org/reports/FBgn0034363 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "NEST:bs33e07, CG5327" "IPR008560:Protein of unknown function DUF842, eukaryotic" CG5327 27-Aug-18 DroID_v2018_08 Drer\fam136a - Cele\ZK637.2 Xtro\fam136a Mmus\Fam136a Hsap\FAM136A viable DRSC06930 K 0.175423074 0.010592763 0.998783334 0.601073732 3.331109329 0.389815284 FBgn0263588 lncRNA:CR43613 - http://flybase.org/reports/FBgn0263588 non_protein_coding_gene - - - "CR43613, lincRNA.892" - CR43613 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0019812 fs(2)R female sterile (2) Ruplekha http://flybase.org/reports/FBgn0019812 - gene - - - fs(2)R - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,viable,female,poor" FBgn0037236 Skp2 S-phase kinase-associated protein 2 http://flybase.org/reports/FBgn0037236 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model regulation of protein stability ; GO:0031647 | inferred from mutant phenotype positive regulation of cell cycle ; GO:0045787 | inferred from mutant phenotype compound eye development ; GO:0048749 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from mutant phenotype mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype endomitotic cell cycle ; GO:0007113 | inferred from mutant phenotype SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | inferred from direct assay "CG9772, 153298_at, Skp2, SKP2, FBXL1, dSkp2, F-box" "IPR001810:F-box domain, IPR032675:Leucine-rich repeat domain, L domain-like, IPR006553:Leucine-rich repeat, cysteine-containing subtype" CG9772 27-Aug-18 DroID_v2018_08 Drer\skp2 Scer\RAD7 "Cele\T28B4.1, Cele\skpt-1" Xtro\skp2 Mmus\Skp2 Hsap\SKP2 "endomitotic cell cycle defective,mitotic cell cycle defective,increased cell death,lethal - all die before end of P-stage,some die during P-stage,viable,visible,decreased cell number,somatic clone" "embryonic/larval salivary gland,embryonic/larval brain,eye disc,wing disc,trichogen cell,wing hair,eye,somatic clone,wing margin,scutellum,mesothoracic tergum,chaeta" FBgn0266788 lncRNA:CR45253 - http://flybase.org/reports/FBgn0266788 non_protein_coding_gene - - - "CR45253, lincRNA.540" - CR45253 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037183 CG14451 - http://flybase.org/reports/FBgn0037183 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - CG14451 IPR013087:Zinc finger C2H2-type CG14451 27-Aug-18 DroID_v2018_08 "Drer\znf366, Drer\atmin" - "Cele\pag-3, Cele\zfp-2" Xtro\atmin "Mmus\Atmin, Mmus\Zfp366" Hsap\ZNF366 viable DRSC11708 I 0.507167396 -2.021058542 -0.557611659 0.372803626 -0.23982946 0.415282259 FBgn0266703 lncRNA:CR45193 - http://flybase.org/reports/FBgn0266703 non_protein_coding_gene - - - "CR45193, lincRNA.793" - CR45193 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264635 cincher cincher http://flybase.org/reports/FBgn0264635 gene - "trachea morphogenesis ; GO:0060439 | inferred from mutant phenotype terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - cincher - - 27-Aug-18 DroID_v2018_08 - - - - - - "embryonic/larval dorsal trunk,embryonic/larval tracheal system,eye,somatic clone" FBgn0040053 CG17674 - http://flybase.org/reports/FBgn0040053 protein_coding_gene - - - CG17674 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0015963 l(2)46DEa lethal (2) 46DEa http://flybase.org/reports/FBgn0015963 - gene - - - "group 5, l(2)46DEa" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0038453 Arl6IP1 ADP-ribosylation factor-like 6 interacting protein 1 http://flybase.org/reports/FBgn0038453 protein_coding_gene - endoplasmic reticulum tubular network membrane organization ; GO:1990809 | inferred from mutant phenotype integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000468827 "CG10326, Arl6IP1" - CG10326 27-Aug-18 DroID_v2018_08 "Drer\arl6ip1, Drer\fam134a" - - Xtro\arl6ip1 "Mmus\Arl6ip1, Mmus\Fam134a" "Hsap\FAM134A, Hsap\ARL6IP1" "viable,fertile" DRSC14231 K 0.423422477 -1.159857152 0.550802758 0.499688451 2.509930766 0.834729044 FBgn0004738 l(3)85De lethal (3) 85De http://flybase.org/reports/FBgn0004738 - gene - - - l(3)85De - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0039984 CG17473 - http://flybase.org/reports/FBgn0039984 protein_coding_gene - - - CG17473 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0022994 ophthalmosa ophthalmosa http://flybase.org/reports/FBgn0022994 - gene - - - "ophthalmosa, opt" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260615 2L3064 - http://flybase.org/reports/FBgn0260615 gene - "epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype" - 2L3064 - - 27-Aug-18 DroID_v2018_08 - - - - - - viable "dorsal air sac primordium,somatic clone" FBgn0265967 lncRNA:CR44754 - http://flybase.org/reports/FBgn0265967 non_protein_coding_gene - - - CR44754 - CR44754 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0053441 5SrRNA:CR33441 5SrRNA:CR33441 http://flybase.org/reports/FBgn0053441 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33441, 5SrRNA:CR33441" - CR33441 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0277427 l(3)psg20 - http://flybase.org/reports/FBgn0277427 gene - - - "l(3)psg20, psg20" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0022266 l(2)k00609 lethal (2) k00609 http://flybase.org/reports/FBgn0022266 - gene - - - l(2)k00609 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0020283 l(3)10532 lethal (3) 10532 http://flybase.org/reports/FBgn0020283 - gene - - - l(3)10532 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0004685 l(1)Mc51 lethal (1) Mc51 http://flybase.org/reports/FBgn0004685 - gene - - - l(1)Mc51 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" "wing,somatic clone,wing hair" FBgn0024307 SS3-1 Suppressor of GMR-sina 3-1 http://flybase.org/reports/FBgn0024307 - gene - - - SS3-1 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0070009 BG01367 BG01367 http://flybase.org/reports/FBgn0070009 gene - - - BG01367 - - 27-Aug-18 DroID_v2018_08 - - - - - - stress response defective FBgn0016829 l(1)MZ16 lethal (1) MZ16 http://flybase.org/reports/FBgn0016829 - gene - - - "l(1)MZ16, M16" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0030162 CG1986 - http://flybase.org/reports/FBgn0030162 protein_coding_gene carboxylic ester hydrolase activity ; GO:0052689 | inferred from electronic annotation with InterPro:IPR000734 lipase activity ; GO:0016298 | inferred from sequence or structural similarity with MGI:MGI:96820 lipid catabolic process ; GO:0016042 | inferred from sequence or structural similarity with MGI:MGI:96820 cellular_component ; GO:0005575 | no biological data available CG1986 "IPR000734:Triacylglycerol lipase family, IPR013818:Lipase/vitellogenin, IPR033906:Lipase, N-terminal, IPR029058:Alpha/Beta hydrolase fold" CG1986 27-Aug-18 DroID_v2018_08 "Drer\lipib, Drer\lipca, Drer\lipg, Drer\LOC100331214, Drer\pla1a, Drer\LOC101884800, Drer\lpl, Drer\lipia" - - "Xtro\lpl, Xtro\lipg" "Mmus\Lpl, Mmus\Pnlip, Mmus\Lipi, Mmus\Lipg, Mmus\Liph, Mmus\Lipc, Mmus\Pla1a, Mmus\Pnliprp1, Mmus\Pnliprp2" "Hsap\PNLIPRP2, Hsap\PLA1A, Hsap\PNLIPRP3, Hsap\LIPC, Hsap\LIPH, Hsap\LPL, Hsap\LIPG, Hsap\PNLIP, Hsap\PNLIPRP1, Hsap\LIPI" FBgn0060850 l(3)S048518 lethal (3) S048518 http://flybase.org/reports/FBgn0060850 gene - - - "0485/18, l(3)S048518" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0040932 CG12650 - http://flybase.org/reports/FBgn0040932 protein_coding_gene - - - CG12650 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036568 ATPsynbetaL "ATP synthase, beta subunit-like" http://flybase.org/reports/FBgn0036568 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000194, InterPro:IPR020003 proton-transporting ATP synthase activity, rotational mechanism ; GO:0046933 | contributes_to inferred from sequence or structural similarity with SGD:S000003882 proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from sequence or structural similarity with SGD:S000003882" ATP synthesis coupled proton transport ; GO:0015986 | inferred from sequence or structural similarity with SGD:S000003882 determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype proton transport ; GO:0015992 | inferred from sequence or structural similarity with UniProtKB:P06576 regulation of proton transport ; GO:0010155 | inferred from mutant phenotype spermatid differentiation ; GO:0048515 | inferred from mutant phenotype "mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) ; GO:0000275 | inferred from sequence or structural similarity with UniProtKB:P06576 lipid particle ; GO:0005811 | inferred from direct assay" "CG5389, ATPB, ATPsynbetaL, ms(3)72Dt" "IPR000194:ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain, IPR003593:AAA+ ATPase domain, IPR004100:ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain, IPR005722:ATP synthase, F1 complex, beta subunit, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR024034:ATPase, F1/V1 complex, beta/alpha subunit, C-terminal, IPR020003:ATPase, alpha/beta subunit, nucleotide-binding domain, active site" CG5389 27-Aug-18 DroID_v2018_08 "Drer\zgc:163069, Drer\atp5b" Scer\ATP2 Cele\atp-2 Xtro\atp5b Mmus\Atp5b Hsap\ATP5B "male sterile,long lived,female,RU486 conditional,female semi-fertile,short lived,calorie restriction conditional,viable,fertile" FBgn0020347 anon-47Ea anon-47Ea http://flybase.org/reports/FBgn0020347 - gene - - - "528, anon-47Ea" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034859 CG3520 - http://flybase.org/reports/FBgn0034859 protein_coding_gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available CG3520 "IPR011989:Armadillo-like helical, IPR022542:Domain of unknown function DUF3730, IPR016024:Armadillo-type fold, IPR021392:Focadhesin" CG3520 27-Aug-18 DroID_v2018_08 Drer\focad - - Xtro\focad Mmus\Focad Hsap\FOCAD "viable,fertile" FBgn0005554 l(3)85Fg lethal (3) 85Fg http://flybase.org/reports/FBgn0005554 - gene - - - l(3)85Fg - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0030815 CG8945 - http://flybase.org/reports/FBgn0030815 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000834 metallocarboxypeptidase activity ; GO:0004181 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000834, InterPro:IPR003146" extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 "CG8945, Cg8945" "IPR000834:Peptidase M14, carboxypeptidase A, IPR009020:Protease propeptides/proteinase inhibitor I9, IPR034223:Insect gut carboxypeptidase-like, carboxypeptidase domain, IPR003146:Carboxypeptidase, activation peptide" CG8945 27-Aug-18 DroID_v2018_08 "Drer\aebp1, Drer\cpa6, Drer\si:ch1073-459j12.1, Drer\cpa2, Drer\cpo, Drer\cpb1, Drer\cpa1, Drer\cpb2, Drer\cpa5, Drer\cpa4" Scer\ECM14 "Cele\F02D8.4, Cele\Y59C2A.1" "Xtro\cpa3, Xtro\cpo, Xtro\cpb1, Xtro\cpb2, Xtro\cpa1" "Mmus\Cpa6, Mmus\Cpb2, Mmus\Cpa2, Mmus\Cpa1, Mmus\Cpa4, Mmus\Cpb1, Mmus\Cpa5, Mmus\Cpa3, Mmus\Cpn1" "Hsap\CPA2, Hsap\CPA3, Hsap\CPA1, Hsap\CPO, Hsap\CPA5, Hsap\CPA4, Hsap\CPNE1, Hsap\CPA6, Hsap\CPB1, Hsap\CPB2" "viable,fertile" FBgn0038046 CG5641 - http://flybase.org/reports/FBgn0038046 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR006116 transferase activity ; GO:0016740 | inferred from electronic annotation with InterPro:IPR006116 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with UniProtKB:Q12905 double-stranded RNA binding ; GO:0003725 | inferred from sequence or structural similarity with UniProtKB:Q12905 "immune response ; GO:0006955 | inferred from electronic annotation with InterPro:IPR006116 positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from sequence or structural similarity with UniProtKB:Q12905 transcription, DNA-templated ; GO:0006351 | inferred from sequence or structural similarity with UniProtKB:Q12905 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013" nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q12905 nucleolus ; GO:0005730 | inferred from sequence or structural similarity with UniProtKB:Q12905 precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay CG5641 "IPR006116:2-5-oligoadenylate synthetase, N-terminal, IPR006561:DZF domain" CG5641 27-Aug-18 DroID_v2018_08 Drer\ilf2 Scer\TAD1 "Cele\R11H6.5, Cele\Y95B8A.8" Xtro\ilf2 Mmus\Ilf2 Hsap\ILF2 viable DRSC15852 E 0.126167555 -0.339090084 -1.603873037 0.347652821 -0.241072059 -0.20936792 FBgn0032421 crok crooked http://flybase.org/reports/FBgn0032421 protein_coding_gene - "regulation of tube size, open tracheal system ; GO:0035151 | inferred from mutant phenotype septate junction assembly ; GO:0019991 | inferred from mutant phenotype" cytoplasm ; GO:0005737 | inferred from direct assay "BcDNA:RE65321, CG17218, crok" - CG17218 27-Aug-18 DroID_v2018_08 - - "Cele\K11H12.6, Cele\K11H12.7, Cele\C15H9.9, Cele\F35C5.11" - - - "lethal,lethal - all die before end of pupal stage,some die during pupal stage" "embryonic/larval dorsal trunk,presumptive embryonic salivary gland,embryonic/larval tracheal system,septate junction" FBgn0002821 ms(2)11R male sterile (2) 11R http://flybase.org/reports/FBgn0002821 - gene - - - ms(2)11R - - 27-Aug-18 DroID_v2018_08 - - - - - - male sterile FBgn0034217 Lhr Lethal hybrid rescue http://flybase.org/reports/FBgn0034217 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR004210 protein binding ; GO:0005515 | inferred from physical interaction with Hmr negative regulation of transposition ; GO:0010529 | inferred from mutant phenotype mitotic sister chromatid segregation ; GO:0000070 | inferred from mutant phenotype regulation of transposition ; GO:0010528 | inferred from mutant phenotype telomere maintenance ; GO:0000723 | inferred from mutant phenotype heterochromatin organization involved in chromatin silencing ; GO:0070868 | inferred from mutant phenotype "chromocenter ; GO:0010369 | inferred from direct assay polytene chromosome, telomeric region ; GO:0035012 | inferred from direct assay heterochromatin ; GO:0000792 | inferred from direct assay chromosome, centromeric region ; GO:0000775 | inferred from direct assay" "CG18468, Lhr, mel-Lhr, HP3, LHR, LHR[[mel]]" IPR004210:BESS motif CG18468 27-Aug-18 DroID_v2018_08 - - - - - - "female semi-sterile,recessive,progressive,viable" FBgn0001784 l(1)M82 lethal (1) M82 http://flybase.org/reports/FBgn0001784 - gene - - - l(1)M82 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" macrochaeta FBgn0263869 lncRNA:CR43716 - http://flybase.org/reports/FBgn0263869 non_protein_coding_gene - - - CR43716 - CR43716 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030317 CG1561 - http://flybase.org/reports/FBgn0030317 protein_coding_gene - - - "e, CG1561" "IPR004119:Protein of unknown function DUF227, IPR011009:Protein kinase-like domain, IPR015897:CHK kinase-like" CG1561 27-Aug-18 DroID_v2018_08 - - "Cele\dhs-27, Cele\H06H21.8, Cele\nhr-246, Cele\F59B1.8, Cele\C29F7.2" - - - partially lethal - majority die FBgn0065373 l(2)SH1692 lethal (2) SH1692 http://flybase.org/reports/FBgn0065373 gene - - - "l(2)SH1692, l(2)SH2 1692" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0001341 Mybbp1A lethal (1) 1Bi http://flybase.org/reports/FBgn0001341 - protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR007015 DNA-directed DNA polymerase activity ; GO:0003887 | inferred from electronic annotation with InterPro:IPR007015 "transcription, DNA-templated ; GO:0006351 | inferred from electronic annotation with InterPro:IPR007015" - "l(1)lBi, EG:115C2.2, CG6189, l(1)Bi, HM-52, HM-419, l(1)1Bi" "IPR007015:DNA polymerase V, IPR011989:Armadillo-like helical, IPR016024:Armadillo-type fold" CG6189 27-Aug-18 DroID_v2018_08 Drer\mybbp1a Scer\POL5 Cele\K04C2.2 - Mmus\Mybbp1a Hsap\MYBBP1A " adult stage , embryonic stage " "wild-type,lethal - all die before end of larval stage,some die during larval stage,lethal,recessive,visible,partially lethal - majority die,lethal - all die before end of pupal stage,some die during pupal stage" macrochaeta FBgn0261679 CG42726 - http://flybase.org/reports/FBgn0261679 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - "CG12258, CG31392, CG42726" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG42726 27-Aug-18 DroID_v2018_08 Drer\zgc:162971 Scer\AZF1 "Cele\C27A2.7, Cele\slr-2" Xtro\LOC100496354 - "Hsap\ZNF44, Hsap\ZNF679" viable FBgn0261565 Lmpt Limpet http://flybase.org/reports/FBgn0261565 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781, InterPro:IPR010442" defense response to fungus ; GO:0050832 | inferred from mutant phenotype - "Lmpt, CG42679, CG11915, CG11914, CG9959, CG11916, CG32171, BcDNA:RE37250, lmpt, CG33256" "IPR001781:Zinc finger, LIM-type, IPR010442:PET domain" CG42679 27-Aug-18 DroID_v2018_08 "Drer\leo1, Drer\fhl2b, Drer\rp1, Drer\fhl2a" Scer\YFR016C Cele\lim-9 "Xtro\leo1, Xtro\fhl2" "Mmus\Fhl2, Mmus\Dmp1, Mmus\Rp1, Mmus\Leo1, Mmus\Ibsp" "Hsap\DMP1, Hsap\FHL2, Hsap\IBSP, Hsap\LEO1, Hsap\RP1" DRSC22921 I 1.762778912 -0.415694471 -0.52595675 -0.322251979 0.200986473 -0.647340685 FBgn0014016 Rbp13 RNA-binding protein 13 http://flybase.org/reports/FBgn0014016 - gene - - - "RBP, Rbp, Rbp13" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004554 Edg91 Ecdysone-dependent gene 91 http://flybase.org/reports/FBgn0004554 - protein_coding_gene structural constituent of pupal chitin-based cuticle ; GO:0008011 | traceable author statement - - "EDG-91, EDG91, CG7539, Edg91" - CG7539 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0013613 l(3)L1042 lethal (3) L1042 http://flybase.org/reports/FBgn0013613 - gene - - - l(3)L1042 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0060781 l(3)S060402 lethal (3) S060402 http://flybase.org/reports/FBgn0060781 gene - - - "0604/02, l(3)S060402" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0069985 BG02201 BG02201 http://flybase.org/reports/FBgn0069985 gene - - - BG02201 - - 27-Aug-18 DroID_v2018_08 - - - - - - stress response defective FBgn0082576 Curled_like Curled like http://flybase.org/reports/FBgn0082576 gene - - - "Curled_like, Cul" - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,dominant" wing FBgn0263465 snoRNA:kis-a - http://flybase.org/reports/FBgn0263465 snoRNA_gene - - - "snoRNA:kis-a, snoCD_02" - CR43580 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266020 lncRNA:CR44785 - http://flybase.org/reports/FBgn0266020 non_protein_coding_gene - - - "CR44785, lincRNA.210" - CR44785 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032448 CG5781 - http://flybase.org/reports/FBgn0032448 protein_coding_gene - - - CG5781 - CG5781 27-Aug-18 DroID_v2018_08 - - Cele\ZK1053.3 - - - viable FBgn0032424 CG17010 - http://flybase.org/reports/FBgn0032424 protein_coding_gene ribokinase activity ; GO:0004747 | inferred from sequence or structural similarity with SGD:S000000632 carbohydrate kinase activity ; GO:0019200 | inferred from biological aspect of ancestor with PANTHER:PTN000061853 D-ribose metabolic process ; GO:0006014 | inferred from sequence or structural similarity with SGD:S000000632 carbohydrate phosphorylation ; GO:0046835 | inferred from biological aspect of ancestor with PANTHER:PTN000061853 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000000632 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000000632 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000061853 CG17010 "IPR002139:Ribokinase/fructokinase, IPR011611:Carbohydrate kinase PfkB, IPR029056:Ribokinase-like, IPR011877:Ribokinase" CG17010 27-Aug-18 DroID_v2018_08 Drer\rbks Scer\RBK1 Cele\F07A11.5 Xtro\rbks Mmus\Rbks Hsap\RBKS FBgn0000222 brw broader wing http://flybase.org/reports/FBgn0000222 - gene - - - brw - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,male,poor,male sterile,visible,recessive" wing FBgn0010890 l(3)06465 lethal (3) 06465 http://flybase.org/reports/FBgn0010890 - gene - - - l(3)06465 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0003653 svs shortened veins http://flybase.org/reports/FBgn0003653 - gene - - - "shv, svs" - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,male fertile,viable,male,reduced,visible" "wing,wing vein,wing vein L4,eye,posterior crossvein" FBgn0029170 TwdlT TweedleT http://flybase.org/reports/FBgn0029170 protein_coding_gene structural constituent of chitin-based cuticle ; GO:0005214 | inferred from sequence or structural similarity with TwdlD body morphogenesis ; GO:0010171 | inferred from sequence or structural similarity with TwdlD chitin-based cuticle development ; GO:0040003 | inferred from sequence or structural similarity with TwdlD proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity with TwdlD "CG5812, GCR(ich), TwdlT" IPR004145:Domain of unknown function DUF243 CG5812 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0014219 l(2)31Db lethal (2) 31Db http://flybase.org/reports/FBgn0014219 - gene - - - l(2)31Db - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0033330 CG8746 - http://flybase.org/reports/FBgn0033330 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG8746 - CG8746 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0038956 CG5379 - http://flybase.org/reports/FBgn0038956 protein_coding_gene carbonate dehydratase activity ; GO:0004089 | inferred from electronic annotation with InterPro:IPR018338 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR018338 one-carbon metabolic process ; GO:0006730 | inferred from electronic annotation with InterPro:IPR018338 - CG5379 "IPR001148:Alpha carbonic anhydrase, IPR018338:Carbonic anhydrase, alpha-class, conserved site, IPR023561:Carbonic anhydrase, alpha-class" CG5379 27-Aug-18 DroID_v2018_08 "Drer\ca14, Drer\ca15c, Drer\ca8, Drer\ca9, Drer\ca2, Drer\ca4b, Drer\ptprga, Drer\ca10b, Drer\zgc:153760, Drer\ca15b, Drer\ca4a, Drer\ca6, Drer\cahz, Drer\ca12, Drer\car15, Drer\ca10a, Drer\ca16b, Drer\ca5a, Drer\si:ch211-173d10.4, Drer\ca15a, Drer\ca7, Drer\ca4c" - "Cele\cah-6, Cele\cah-4, Cele\cah-3, Cele\cah-5" "Xtro\ca7, Xtro\ca10, Xtro\ca11, Xtro\ca4, Xtro\ca3, Xtro\ca5b, Xtro\ca14, Xtro\ca6, Xtro\ca2, Xtro\ca12, Xtro\LOC779564, Xtro\ca1, Xtro\ca8" "Mmus\Car12, Mmus\Ptprg, Mmus\Car6, Mmus\Car8, Mmus\Car13, Mmus\Car15, Mmus\Car5b, Mmus\Car9, Mmus\Car1, Mmus\Car11, Mmus\Car3, Mmus\Car5a, Mmus\Car2, Mmus\Car4, Mmus\Car7, Mmus\Car14, Mmus\Car10" "Hsap\CA5B, Hsap\CA14, Hsap\PTPRG, Hsap\CA9, Hsap\CA13, Hsap\CA2, Hsap\CA3, Hsap\CA10, Hsap\CA5A, Hsap\CA1, Hsap\CA8, Hsap\CA4, Hsap\CA12, Hsap\CA11, Hsap\CA7, Hsap\CA6" viable FBgn0016668 Hrp70 Hrp70 http://flybase.org/reports/FBgn0016668 - gene single-stranded DNA binding ; GO:0003697 | inferred from direct assay biological_process ; GO:0008150 | no biological data available nucleolus ; GO:0005730 | NOT inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "hrp70, Hrp70" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0019690 l(3)69Ai lethal (3) 69Ai http://flybase.org/reports/FBgn0019690 - gene - - - "l(3)69Ab, l(3)69Ai" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0265747 lncRNA:CR44554 - http://flybase.org/reports/FBgn0265747 non_protein_coding_gene - - - "CR44554, lincRNA.531" - CR44554 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0022102 l(2)k07126 lethal (2) k07126 http://flybase.org/reports/FBgn0022102 - gene - - - l(2)k07126 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0053401 5SrRNA:CR33401 5SrRNA:CR33401 http://flybase.org/reports/FBgn0053401 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33401, 5SrRNA:CR33401" - CR33401 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065760 l(2)SH0479 lethal (2) SH0479 http://flybase.org/reports/FBgn0065760 gene - - - "l(2)SH0479, l(2)SH2 0479" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0036150 Ir68a Ionotropic receptor 68a http://flybase.org/reports/FBgn0036150 protein_coding_gene ionotropic glutamate receptor activity ; GO:0004970 | inferred from electronic annotation with InterPro:IPR001320 ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001320 integral component of membrane ; GO:0016021 | inferred from sequence model "Ir68a, CT19410, CG6185, DmelIR68a, IR68a" IPR001320:Ionotropic glutamate receptor CG6185 27-Aug-18 DroID_v2018_08 "Drer\grid2, Drer\grid1b, Drer\LOC100537813, Drer\grid1a" - - - "Mmus\Grik4, Mmus\Grid1" Hsap\GRID1 "viable,fertile" FBgn0260292 GSd436 - http://flybase.org/reports/FBgn0260292 gene - - - GSd436 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0265206 T:Mito-CG9393 Mitochondrial outer membrane targeting sequence of CG9393 http://flybase.org/reports/FBgn0265206 engineered_tag - - - T:Mito-CG9393 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032870 CG2608 - http://flybase.org/reports/FBgn0032870 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001374 - - "38D.26, CG2608" "IPR001374:R3H domain, IPR017330:Sperm-associated antigen 7, IPR034068:Sperm-associated antigen 7, R3H domain" CG2608 27-Aug-18 DroID_v2018_08 Drer\spag7 - - - Mmus\Spag7 Hsap\SPAG7 "viable,visible" "embryonic/larval hemocyte | third instar larval stage,trichogen cell" FBgn0260501 Pkn::Mmus\Rtkn - http://flybase.org/reports/FBgn0260501 engineered_fusion_gene - - - "Pkn::Mmus\Rtkn, Rhot-Pkn" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002354 l(3)87Df lethal (3) 87Df http://flybase.org/reports/FBgn0002354 "FBgn0038112, FBgn0062841" protein_coding_gene molecular_function ; GO:0003674 | no biological data available mitochondrial respiratory chain complex IV assembly ; GO:0033617 | inferred from biological aspect of ancestor with PANTHER:PTN001269069 aerobic respiration ; GO:0009060 | inferred from biological aspect of ancestor with PANTHER:PTN001269069 mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN001269069 "l(3)S12, l(3)s12, S12, CG7620, BcDNA:SD27354, l(3)87Df" "IPR022533:Cox20/FAM36A, IPR023242:FAM36A" CG7620 27-Aug-18 DroID_v2018_08 Drer\cox20 Scer\COX20 - Xtro\cox20 Mmus\Cox20 Hsap\COX20 "viable,fertile,wild-type,lethal,recessive,cold sensitive,female sterile,partially,heat sensitive" macrochaeta FBgn0038438 Der-2 Derlin-2 http://flybase.org/reports/FBgn0038438 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR022764 molecular_function ; GO:0003674 | no biological data available endoplasmic reticulum unfolded protein response ; GO:0030968 | inferred from sequence or structural similarity with HGNC:17943 defense response to bacterium ; GO:0042742 | inferred from mutant phenotype ER-associated ubiquitin-dependent protein catabolic process ; GO:0030433 | inferred from sequence or structural similarity with HGNC:17943 integral component of endoplasmic reticulum membrane ; GO:0030176 | inferred from sequence or structural similarity with HGNC:17943 "DER1, Der-2, CG14899, Cg14899" "IPR007599:Derlin, IPR022764:Peptidase S54, rhomboid domain" CG14899 27-Aug-18 DroID_v2018_08 "Drer\derl2, Drer\derl3, Drer\derl1" "Scer\DER1, Scer\DFM1" "Cele\cup-2, Cele\R151.6" "Xtro\derl2, Xtro\derl1" "Mmus\Derl1, Mmus\Derl3, Mmus\Derl2" "Hsap\DERL3, Hsap\DERL2, Hsap\DERL1" FBgn0069231 gl(2L)260-24 gl(2L)260-24 http://flybase.org/reports/FBgn0069231 gene molecular_function ; GO:0003674 | no biological data available morphogenesis of embryonic epithelium ; GO:0016331 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available gl(2L)260-24 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,germline clone,non-rescuable maternal effect,recessive" "embryonic/first instar larval cuticle,germline clone,maternal effect" FBgn0003362 sesE stress-sensitive E http://flybase.org/reports/FBgn0003362 - gene - - - sesE - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,heat sensitive,paralytic,somatic clone,behavior defective" "leg,somatic clone" FBgn0260401 MED9 Mediator complex subunit 9 http://flybase.org/reports/FBgn0260401 protein_coding_gene RNA polymerase II transcription cofactor activity ; GO:0001104 | inferred from sequence or structural similarity with UniProtKB:Q9VEC1 regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from electronic annotation with InterPro:IPR011425 negative regulation of neuroblast proliferation ; GO:0007406 | inferred from mutant phenotype transcription from RNA polymerase II promoter ; GO:0006366 | inferred from sequence or structural similarity with UniProtKB:Q9VEC1 mediator complex ; GO:0016592 | inferred from sequence or structural similarity with UniProtKB:Q9VEC1 mediator complex ; GO:0016592 | inferred from biological aspect of ancestor with PANTHER:PTN000464837 "MED9, CG5134, CG30112, CG30113, BcDNA:LD07740, BcDNA:RH42446, CG42517, med9, Med9" IPR011425:Mediator of RNA polymerase II transcription subunit 9 CG42517 27-Aug-18 DroID_v2018_08 Drer\si:ch73-105m5.1 - - Xtro\med9 Mmus\Med9 Hsap\MED9 DRSC06917 K -1.291763872 1.456262888 -1.139790733 0.540936479 1.892200088 2.329893108 FBgn0035907 GstO1 Glutathione S transferase O1 http://flybase.org/reports/FBgn0035907 protein_coding_gene "glutathione transferase activity ; GO:0004364 | inferred from direct assay glutathione dehydrogenase (ascorbate) activity ; GO:0045174 | inferred from direct assay pyrimidodiazepine synthase activity ; GO:0004734 | NOT inferred from direct assay transferase activity, transferring sulfur-containing groups ; GO:0016782 | inferred from direct assay" glutathione metabolic process ; GO:0006749 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with RGD:70952 "GstO1, GSTO1, CG6662, DmGSTO1" "IPR004045:Glutathione S-transferase, N-terminal, IPR005442:Glutathione S-transferase, omega-class, IPR010987:Glutathione S-transferase, C-terminal-like, IPR012336:Thioredoxin-like fold" CG6662 27-Aug-18 DroID_v2018_08 "Drer\gsto2, Drer\gsto1" - "Cele\gsto-3, Cele\gsto-1, Cele\C02D5.4, Cele\gst-44, Cele\gsto-2" "Xtro\LOC100498493, Xtro\gsto2, Xtro\gsto1" "Mmus\Gsto2, Mmus\Gsto1" "Hsap\GSTO1, Hsap\GSTO2" viable DRSC10688 I 0.784712297 1.521778987 -0.353827186 0.135821259 0.443717298 0.145578918 FBgn0011679 NssBF Nuclear single stranded DNA-binding factor http://flybase.org/reports/FBgn0011679 - gene single-stranded DNA binding ; GO:0003697 | inferred from direct assay - - NssBF - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262972 lncRNA:CR43283 - http://flybase.org/reports/FBgn0262972 non_protein_coding_gene - - - "CR43283, Dm_3R:37919, lincRNA.752" - CR43283 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0030239 CG17333 - http://flybase.org/reports/FBgn0030239 protein_coding_gene 6-phosphogluconolactonase activity ; GO:0017057 | inferred from biological aspect of ancestor with PANTHER:PTN000114544 "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR005900, InterPro:IPR006148 pentose-phosphate shunt, oxidative branch ; GO:0009051 | inferred from biological aspect of ancestor with PANTHER:PTN000114544" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000114544 "CG17333, Pgls" "IPR005900:6-phosphogluconolactonase, DevB-type, IPR006148:Glucosamine/galactosamine-6-phosphate isomerase" CG17333 27-Aug-18 DroID_v2018_08 "Drer\pgls, Drer\h6pd, Drer\gnpda1" "Scer\SOL3, Scer\SOL1, Scer\SOL4, Scer\SOL2" Cele\Y57G11C.3 "Xtro\h6pd, Xtro\pgls" "Mmus\Pgls, Mmus\H6pd" "Hsap\PGLS, Hsap\H6PD" "viable,fertile" FBgn0051210 CG31210 - http://flybase.org/reports/FBgn0051210 protein_coding_gene - - - "CG31210, CG4836" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040740 CG14494 - http://flybase.org/reports/FBgn0040740 protein_coding_gene - - - CG14494 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0069203 l(2)46Fa lethal (2) 46Fa http://flybase.org/reports/FBgn0069203 gene - - - l(2)46Fa - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0028392 anon-50ABb anon-50ABb http://flybase.org/reports/FBgn0028392 gene - - - "B, anon-50ABb" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065943 l(2)SH0109 lethal (2) SH0109 http://flybase.org/reports/FBgn0065943 gene - - - "l(2)SH0109, l(2)SH2 0109" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0035546 CG11345 - http://flybase.org/reports/FBgn0035546 protein_coding_gene - - - CG11345 - CG11345 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0261841 pre-mod(mdg4)-AD - http://flybase.org/reports/FBgn0261841 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "pre-mod(mdg4)-AD, CG42773, RAD" "IPR007588:Zinc finger, FLYWCH-type" CG42773 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033497 CG12912 - http://flybase.org/reports/FBgn0033497 protein_coding_gene - - - CG12912 - CG12912 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031643 CG3008 - http://flybase.org/reports/FBgn0031643 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000687, InterPro:IPR017406 protein serine/threonine kinase activity ; GO:0004674 | inferred from electronic annotation with InterPro:IPR000687, InterPro:IPR017406 protein kinase activity ; GO:0004672 | inferred from sequence or structural similarity with SGD:S000005645" protein phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with SGD:S000005645 nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD:S000005645 cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD:S000005645 CG3008 "IPR000687:RIO kinase, IPR011009:Protein kinase-like domain, IPR017406:Serine/threonine-protein kinase Rio3" CG3008 27-Aug-18 DroID_v2018_08 Drer\riok3 Scer\RIO1 Cele\riok-3 Xtro\riok3 Mmus\Riok3 Hsap\RIOK3 viable DRSC00560 I 1.853955276 0.044058262 0.205067846 0.01739177 0.082206766 0.184365511 FBgn0263073 GS5246 - http://flybase.org/reports/FBgn0263073 gene - - - GS5246 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000372 cripA crippled A http://flybase.org/reports/FBgn0000372 - gene molecular_function ; GO:0003674 | no biological data available flight behavior ; GO:0007629 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "crpA, cripA" - - 27-Aug-18 DroID_v2018_08 - - - - - - "hypoactive,uncoordinated" FBgn0035070 CG3650 - http://flybase.org/reports/FBgn0035070 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "SP159, CG3650" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site" CG3650 27-Aug-18 DroID_v2018_08 - - "Cele\try-1, Cele\try-5, Cele\svh-1" - Mmus\Gzmk - pupal stage salivary gland

viable FBgn0082936 snoRNA:Me28S-C2645c - http://flybase.org/reports/FBgn0082936 snoRNA_gene - - - "CR34589, snoRNA:Me28S-C2645c, Me28S-Cm2645c, snoRNA:Me28S-Cm2645c, DmSnR64c" - CR34589 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0052728 CR32728 - http://flybase.org/reports/FBgn0052728 non_protein_coding_gene - - - CR32728 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0019847 anon-XVIII anon-XVIII http://flybase.org/reports/FBgn0019847 - gene - - - "XVIII, anon-XVIII" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0013594 l(3)A519.1F3 lethal (3) A519.1F3 http://flybase.org/reports/FBgn0013594 - gene - - - l(3)A519.1F3 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0069244 daltonian daltonian http://flybase.org/reports/FBgn0069244 gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available daltonian - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0086021 snoRNA:MeU6-C68 - http://flybase.org/reports/FBgn0086021 snoRNA_gene - - - "snoRNA:MeU6-C68, MeU6-Cm68, MeU6-C68, CR34650, mgU6-68" - CR34650 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0069079 stoc stocherkahn http://flybase.org/reports/FBgn0069079 gene molecular_function ; GO:0003674 | no biological data available embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available stoc - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive,lethal,germline clone,non-rescuable maternal effect" "dorsal closure embryo,germline clone,non-rescuable maternal effect,maternal effect" FBgn0019985 mGluR metabotropic Glutamate Receptor http://flybase.org/reports/FBgn0019985 - protein_coding_gene group II metabotropic glutamate receptor activity ; GO:0001641 | inferred from direct assay glutamate binding ; GO:0016595 | inferred from direct assay G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity glutamate receptor activity ; GO:0008066 | inferred from sequence or structural similarity cholesterol binding ; GO:0015485 | inferred from direct assay "long-term memory ; GO:0007616 | inferred from mutant phenotype terminal button organization ; GO:0072553 | inferred from mutant phenotype neuromuscular junction development ; GO:0007528 | inferred from mutant phenotype learning ; GO:0007612 | inferred from mutant phenotype short-term memory ; GO:0007614 | inferred from mutant phenotype regulation of synaptic transmission, glutamatergic ; GO:0051966 | inferred from mutant phenotype G-protein coupled glutamate receptor signaling pathway ; GO:0007216 | inferred from direct assay male courtship behavior ; GO:0008049 | inferred from mutant phenotype G-protein coupled glutamate receptor signaling pathway ; GO:0007216 | inferred from sequence or structural similarity" integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity G-protein coupled receptor homodimeric complex ; GO:0038038 | inferred from sequence or structural similarity with HGNC:4593 integral component of plasma membrane ; GO:0005887 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay membrane raft ; GO:0045121 | inferred from direct assay "CAA67993.1_Dr, DmGluAR, DmGluRA, DmGlu-A, DmGluR[[A]], DmGluR, dmGluRA, CG11144, mGluR, DmGlu-RA, Glu-RA, DmGlu[[A]]R, DmGluA, GluR, mGLuR, mGluRA" "IPR017978:GPCR family 3, C-terminal, IPR017979:GPCR, family 3, conserved site, IPR000162:GPCR, family 3, metabotropic glutamate receptor, IPR000337:GPCR, family 3, IPR001828:Receptor, ligand binding region, IPR011500:GPCR, family 3, nine cysteines domain, IPR028082:Periplasmic binding protein-like I" CG11144 27-Aug-18 DroID_v2018_08 "Drer\grm1b, Drer\grm5b, Drer\grm5a, Drer\grm6a, Drer\si:ch1073-155h21.1, Drer\grm8a, Drer\grm2b, Drer\grm6b, Drer\grm3, Drer\grm4, Drer\gprc5c, Drer\tas1r3, Drer\tas1r2.1, Drer\gprc5bb, Drer\grm1a, Drer\grm8b, Drer\tas1r2.2, Drer\grm2a" - "Cele\mgl-3, Cele\mgl-2, Cele\mgl-1" "Xtro\gprc5a, Xtro\grm5, Xtro\gprc5c, Xtro\gprc5c, Xtro\grm3, Xtro\grm4, Xtro\grm7, Xtro\grm1" "Mmus\Vmn2r20, Mmus\Vmn2r102, Mmus\Vmn2r106, Mmus\Vmn2r90, Mmus\Vmn2r108, Mmus\Vmn2r94, Mmus\Vmn2r110, Mmus\Gprc5b, Mmus\Vmn2r109, Mmus\Grm3, Mmus\Vmn2r58, Mmus\Vmn2r92, Mmus\Grm1, Mmus\Grm7, Mmus\Vmn2r100, Mmus\Vmn2r104, Mmus\Grm5, Mmus\Vmn2r21, Mmus\Tas1r1, Mmus\Grm4, Mmus\Vmn2r59, Mmus\Tas1r3, Mmus\Vmn2r60, Mmus\Vmn2r56, Mmus\Vmn2r97, Mmus\Vmn2r105, Mmus\Grm2, Mmus\Vmn2r22, Mmus\Grm6, Mmus\Grm8, Mmus\Gprc5d, Mmus\Vmn2r61, Mmus\Vmn2r98, Mmus\Gprc5a" "Hsap\GRM2, Hsap\GRM3, Hsap\GPRC5C, Hsap\GPRC5D, Hsap\TAS1R3, Hsap\GPRC5B, Hsap\GRM4, Hsap\GRM5, Hsap\GRM7, Hsap\GPRC5A, Hsap\GRM1, Hsap\GRM6, Hsap\TAS1R1, Hsap\GRM8" "viable,neurophysiology defective,neuroanatomy defective,recessive" "type I bouton,bouton,supernumerary" FBgn0039483 CG14259 - http://flybase.org/reports/FBgn0039483 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available extracellular space ; GO:0005615 | inferred from sequence or structural similarity with to CG14259 IPR010562:Haemolymph juvenile hormone binding CG14259 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0265704 lncRNA:CR44511 - http://flybase.org/reports/FBgn0265704 non_protein_coding_gene - - - "lincRNA.396, CR44511" - CR44511 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033913 CG8468 - http://flybase.org/reports/FBgn0033913 protein_coding_gene - transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701 integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR011701 CG8468 "IPR011701:Major facilitator superfamily, IPR020846:Major facilitator superfamily domain" CG8468 27-Aug-18 DroID_v2018_08 "Drer\slc16a4, Drer\slc16a6b, Drer\LOC103911912, Drer\slc16a12b, Drer\slc16a6a, Drer\zgc:114041, Drer\mfsd6b, Drer\si:dkey-246g23.4, Drer\slc16a12a, Drer\slc16a13, Drer\slc16a9b, Drer\slc16a9a" "Scer\MCH2, Scer\MCH4, Scer\ESBP6, Scer\ATG22, Scer\MCH5" "Cele\mct-6, Cele\mct-1, Cele\mct-2, Cele\mct-5, Cele\mct-4, Cele\mct-3" Xtro\slc16a9 "Mmus\Slc16a12, Mmus\Slc16a9, Mmus\Slc16a14, Mmus\Slc16a4, Mmus\Slc16a11, Mmus\Slc16a6, Mmus\Slc16a13" "Hsap\SLC16A13, Hsap\SLC16A9, Hsap\SLC16A11, Hsap\SLC16A4, Hsap\SLC16A14, Hsap\SLC16A6, Hsap\SLC16A12, Hsap\SLC16A8" viable FBgn0003532 stmC stambha C http://flybase.org/reports/FBgn0003532 - gene - - - "stm-C, stmC" - - 27-Aug-18 DroID_v2018_08 - - - - - - "paralytic,recessive,heat sensitive" FBgn0005507 l(2)24EFe lethal (2) 24EFe http://flybase.org/reports/FBgn0005507 - gene - - - "l(2)Gr.V, l(2)24EFe" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0010055 JmX Ju myoX http://flybase.org/reports/FBgn0010055 - gene - - - "Jm X, X, JmX" - - 27-Aug-18 DroID_v2018_08 - - - - - - long lived FBgn0013933 E(Pc)17B E(Pc)17B http://flybase.org/reports/FBgn0013933 - gene - - - "E(Pc)14B, E(Pc)17B" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0058418 CG40418 - http://flybase.org/reports/FBgn0058418 protein_coding_gene - - - CG40418 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0053452 5SrRNA:CR33452 5SrRNA:CR33452 http://flybase.org/reports/FBgn0053452 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33452, 5SrRNA:CR33452" - CR33452 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035929 CG13311 - http://flybase.org/reports/FBgn0035929 protein_coding_gene - - - "BcDNA:RE29808, CG13311" - CG13311 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267064 lncRNA:CR45508 - http://flybase.org/reports/FBgn0267064 non_protein_coding_gene - - - CR45508 - CR45508 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0083290 E(smoDN)2042 Enhancer of smoDN 2042 http://flybase.org/reports/FBgn0083290 gene - - - E(smoDN)2042 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038621 CG10864 - http://flybase.org/reports/FBgn0038621 protein_coding_gene "potassium channel activity ; GO:0005267 | inferred from sequence or structural similarity with Task7, Task6" "potassium ion transmembrane transport ; GO:0071805 | inferred from sequence or structural similarity with Task7, Task6" "integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with Task7, Task6" CG10864 "IPR003280:Two pore domain potassium channel, IPR013099:Potassium channel domain" CG10864 27-Aug-18 DroID_v2018_08 "Drer\kcnk5b, Drer\kcnk10b, Drer\kcnk10a, Drer\kcnk5a, Drer\kcnk1a, Drer\kcnk6, Drer\kcnk7, Drer\kcnk18, Drer\kcnk2a, Drer\kcnk1b" Scer\TOK1 "Cele\twk-24, Cele\twk-48, Cele\twk-39, Cele\twk-28" "Xtro\LOC100486031, Xtro\kcnk1, Xtro\kcnk4, Xtro\kcnk16, Xtro\kcnk5, Xtro\kcnk6, Xtro\kcnk2, Xtro\kcnk7, Xtro\kcnk18, Xtro\kcnk10" "Mmus\Kcnk10, Mmus\Kcnk6, Mmus\Kcnk12, Mmus\Kcnk18, Mmus\Kcnk5, Mmus\Kcnk7, Mmus\Kcnk16, Mmus\Kcnk4, Mmus\Kcnk1, Mmus\Kcnk2" "Hsap\KCNK4, Hsap\KCNK18, Hsap\KCNK5, Hsap\KCNK7, Hsap\KCNK2, Hsap\KCNK10, Hsap\KCNK12, Hsap\KCNK16, Hsap\KCNK17, Hsap\KCNK6, Hsap\KCNK1" viable FBgn0264957 lncRNA:CR44126 - http://flybase.org/reports/FBgn0264957 non_protein_coding_gene - - - "lincRNA.251, CR44126" - CR44126 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0265930 lncRNA:CR44719 - http://flybase.org/reports/FBgn0265930 non_protein_coding_gene - - - CR44719 - CR44719 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267553 lncRNA:CR45893 - http://flybase.org/reports/FBgn0267553 non_protein_coding_gene - - - CR45893 - CR45893 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267522 28SrRNA-Psi:CR45862 28S ribosomal RNA pseudogene:CR45862 http://flybase.org/reports/FBgn0267522 pseudogene_attribute - - - "28SrRNA-Psi:CR45862, CR45862" - CR45862 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259328 C109 - http://flybase.org/reports/FBgn0259328 gene - - - C109 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible wing FBgn0263451 asRNA:CR43474 - http://flybase.org/reports/FBgn0263451 non_protein_coding_gene - - - CR43474 - CR43474 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037753 CG12947 - http://flybase.org/reports/FBgn0037753 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG12947 - CG12947 27-Aug-18 DroID_v2018_08 - - - - Mmus\Wfdc8 Hsap\WFDC8 viable FBgn0267755 lncRNA:CR46086 - http://flybase.org/reports/FBgn0267755 non_protein_coding_gene - - - CR46086 - CR46086 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002038 l(2)37Db lethal (2) 37Db http://flybase.org/reports/FBgn0002038 - gene - - - "E19, l(2)E19, l(2)37Db" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0266823 lncRNA:CR45285 - http://flybase.org/reports/FBgn0266823 non_protein_coding_gene - - - CR45285 - CR45285 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0017373 l(2)C103 lethal (2) C103 http://flybase.org/reports/FBgn0017373 - gene - - - "C103, l(2)C103" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage" macrochaeta FBgn0010556 l(2)03788 lethal (2) 03788 http://flybase.org/reports/FBgn0010556 - gene - - - l(2)03788 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,partially lethal - majority die" FBgn0005311 ms(2)73d male sterile (2) 73d http://flybase.org/reports/FBgn0005311 - gene - - - ms(2)73d - - 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,recessive" spermatid FBgn0002019 l(2)37Ac lethal (2) 37Ac http://flybase.org/reports/FBgn0002019 - gene - - - "37Ac, Ac, l(2)E145, l(2)37Ac" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0259761 dolly-2 double loops of the Y 2 http://flybase.org/reports/FBgn0259761 gene - spermatogenesis ; GO:0007283 | inferred from mutant phenotype chromosome organization ; GO:0051276 | inferred from mutant phenotype - "142-046, dolly-2, ms(3)142-46" - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,male sterile" "Y chromosome loop,spermatozoon" FBgn0011084 l(1)Q42 lethal (1) Q42 http://flybase.org/reports/FBgn0011084 FBgn0010210 gene - - - l(1)Q42 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0003486 spo spook http://flybase.org/reports/FBgn0003486 FBgn0035618 protein_coding_gene "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; GO:0016705 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 heme binding ; GO:0020037 | inferred from sequence model oxidoreductase activity ; GO:0016491 | inferred from sequence model" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401, InterPro:IPR017972 midgut development ; GO:0007494 | inferred from mutant phenotype ecdysone biosynthetic process ; GO:0006697 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype embryonic digestive tract development ; GO:0048566 | inferred from mutant phenotype dorsal closure ; GO:0007391 | inferred from mutant phenotype cuticle development ; GO:0042335 | inferred from mutant phenotype embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype head involution ; GO:0008258 | inferred from mutant phenotype central nervous system development ; GO:0007417 | inferred from mutant phenotype" endoplasmic reticulum ; GO:0005783 | inferred from direct assay "Cyp307a1, CYP307A1-Dm, 307a1, Spo, CG10594, spo, Dmspo, spook, CYP307A1" "IPR017972:Cytochrome P450, conserved site, IPR001128:Cytochrome P450, IPR002401:Cytochrome P450, E-class, group I" CG10594 27-Aug-18 DroID_v2018_08 "Drer\cyp1d1, Drer\cyp2x6, Drer\cyp2x7, Drer\cyp2aa12, Drer\cyp21a2, Drer\cyp2p8, Drer\cyp2k16, Drer\cyp2p6, Drer\cyp2x8, Drer\cyp2k21, Drer\cyp2u1, Drer\cyp2k31, Drer\cyp1b1, Drer\si:zfos-411a11.2, Drer\cyp2aa2, Drer\cyp2p7, Drer\cyp2aa6, Drer\cyp2j20, Drer\cyp2n13, Drer\cyp17a1, Drer\cyp2k18, Drer\cyp2k20, Drer\cyp2x10.2, Drer\cyp2aa1, Drer\cyp2x9, Drer\cyp2x12, Drer\cyp1a, Drer\cyp2k19, Drer\cyp2aa11, Drer\cyp2ad6, Drer\cyp2r1, Drer\cyp17a2, Drer\cyp2aa8, Drer\cyp2k22, Drer\cyp2y3, Drer\cyp2aa4, Drer\cyp2k17, Drer\cyp2k8, Drer\cyp2aa3, Drer\cyp2aa9, Drer\cyp2ad2, Drer\cyp2ae1, Drer\si:dkey-286h2.7, Drer\LOC100148115" - Cele\cyp-14A4 "Xtro\cyp2b6, Xtro\cyp21a2.1, Xtro\LOC100486127, Xtro\cyp2c8.1, Xtro\cyp2d6, Xtro\cyp2g1p, Xtro\LOC100493194, Xtro\cyp1a1, Xtro\cyp2c8.2, Xtro\LOC100036663, Xtro\cyp2u1, Xtro\MGC107969, Xtro\LOC100145323, Xtro\cyp2j2, Xtro\LOC100145541, Xtro\LOC548374, Xtro\cyp2e1, Xtro\cyp2f2, Xtro\cyp2a13, Xtro\LOC100497460, Xtro\LOC100497184, Xtro\LOC100145084, Xtro\cyp2a6, Xtro\LOC100145695, Xtro\cyp1b1, Xtro\cyp1d1, Xtro\cyp2r1, Xtro\MGC69353, Xtro\cyp2w1, Xtro\LOC619584, Xtro\MGC69416, Xtro\cyp17a1" "Mmus\Cyp2b10, Mmus\Cyp2d22, Mmus\Cyp2e1, Mmus\Cyp2d40, Mmus\Cyp2d10, Mmus\Cyp2j11, Mmus\Cyp2c39, Mmus\Cyp2b23, Mmus\Cyp2c66, Mmus\Cyp2b9, Mmus\Cyp2j8, Mmus\Cyp2c50, Mmus\Cyp2j12, Mmus\Cyp2j5, Mmus\Cyp2c55, Mmus\Cyp2b13, Mmus\Cyp2c68, Mmus\Cyp2d34, Mmus\Cyp17a1, Mmus\Cyp1a2, Mmus\Cyp2c54, Mmus\Cyp1a1, Mmus\Cyp21a1, Mmus\Cyp2j13, Mmus\Cyp2u1, Mmus\Cyp2a22, Mmus\Cyp2c67, Mmus\Cyp2a12, Mmus\Cyp2c44, Mmus\Cyp2c37, Mmus\Cyp2c65, Mmus\Cyp2d26, Mmus\Cyp2c70, Mmus\Cyp2r1, Mmus\Cyp2s1, Mmus\Cyp2d11, Mmus\Cyp2d9, Mmus\Cyp2j6, Mmus\Cyp2c40, Mmus\Cyp1b1, Mmus\Cyp2b19, Mmus\Cyp2a5, Mmus\Cyp2j9, Mmus\Cyp2ab1, Mmus\Cyp2c29, Mmus\Cyp2g1, Mmus\Cyp2w1, Mmus\Cyp2a4, Mmus\Cyp2c38, Mmus\Cyp2d12, Mmus\Cyp2f2, Mmus\Cyp2c69, Mmus\Cyp2t4" "Hsap\CYP2F1, Hsap\CYP1A2, Hsap\CYP2C9, Hsap\CYP2A7, Hsap\CYP2W1, Hsap\CYP21A2, Hsap\CYP2U1, Hsap\CYP2C19, Hsap\CYP17A1, Hsap\CYP2R1, Hsap\CYP2E1, Hsap\CYP2A6, Hsap\CYP3A43, Hsap\CYP2S1, Hsap\CYP2C8, Hsap\CYP2A13, Hsap\CYP1B1, Hsap\CYP2C18, Hsap\CYP1A1, Hsap\CYP2D6, Hsap\CYP2B6, Hsap\CYP2J2" "lethal - all die before end of embryonic stage,recessive,some die during embryonic stage,viable,fertile,lethal" "embryonic/larval midgut,presumptive embryonic/larval central nervous system,commissure,embryonic epidermis,presumptive embryonic/larval peripheral nervous system,sensory neuron,cephalopharyngeal skeleton,embryonic/first instar larval cuticle,dorsal closure embryo,embryonic ventral epidermis,ventral nerve cord,embryonic/larval foregut,embryonic/larval hindgut,longitudinal connective,glial cell,midline glial cell,ectopic,midgut primordium,denticle belt,embryonic hindgut" FBgn0263250 CG43393 - http://flybase.org/reports/FBgn0263250 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG43393 - CG43393 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038862 Usp8 Ubiquitin specific protease 8 http://flybase.org/reports/FBgn0038862 protein_coding_gene thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from direct assay ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from electronic annotation with InterPro:IPR018200 positive regulation of canonical Wnt signaling pathway ; GO:0090263 | inferred from mutant phenotype neuron remodeling ; GO:0016322 | inferred from mutant phenotype positive regulation of smoothened signaling pathway ; GO:0045880 | inferred from genetic interaction with smo protein deubiquitination ; GO:0016579 | inferred from mutant phenotype imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay "CT18196, USP8, CG5798, dUBPY, usp8, UBPY, UBPY/USP8, UbpY, Usp8, Ubpy, Q9VDD8, ubpy" "IPR001394:Peptidase C19, ubiquitin carboxyl-terminal hydrolase, IPR001763:Rhodanese-like domain, IPR018200:Ubiquitin specific protease, conserved site, IPR028889:Ubiquitin specific protease domain, IPR015063:USP8 dimerisation domain" CG5798 27-Aug-18 DroID_v2018_08 "Drer\usp2a, Drer\usp32, Drer\usp2b, Drer\usp8, Drer\usp11, Drer\usp4, Drer\usp1, Drer\usp21, Drer\usp43b" "Scer\DOA4, Scer\UBP8, Scer\UBP7, Scer\UBP11, Scer\UBP5, Scer\UBP12" "Cele\usp-3, Cele\cyk-3, Cele\F07A11.4, Cele\H34C03.2, Cele\usp-50, Cele\usp-33" "Xtro\usp21, Xtro\usp8, Xtro\usp2, Xtro\usp15, Xtro\usp37" "Mmus\Usp8, Mmus\Usp22, Mmus\Usp15, Mmus\Usp1, Mmus\Usp32, Mmus\Usp27x, Mmus\Usp26, Mmus\Usp3, Mmus\Usp21, Mmus\Usp29, Mmus\Usp37, Mmus\Usp4, Mmus\Usp43, Mmus\Usp2, Mmus\Usp50, Mmus\Usp11" "Hsap\USP11, Hsap\USP26, Hsap\USP21, Hsap\USP3, Hsap\USP29, Hsap\USP43, Hsap\USP4, Hsap\USP37, Hsap\USP50, Hsap\USP22, Hsap\USP8, Hsap\USP27X, Hsap\USP1, Hsap\USP2, Hsap\USP32" "visible,locomotor rhythm defective,lethal,lethal - all die before end of pupal stage,somatic clone,some die during pupal stage,lethal - all die before end of embryonic stage,some die during embryonic stage,lethal - all die before end of larval stage,some die during larval stage" "wing,wing vein L3,wing margin bristle" FBgn0031613 HP6 Heterochromatin protein 6 http://flybase.org/reports/FBgn0031613 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q95RV2 chromatin binding ; GO:0003682 | inferred from sequence or structural similarity with Su(var)205 female meiotic division ; GO:0007143 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype telomere capping ; GO:0016233 | inferred from mutant phenotype chromosome organization ; GO:0051276 | inferred from sequence or structural similarity with Su(var)205 "heterochromatin ; GO:0000792 | inferred from direct assay chromosome, centromeric region ; GO:0000775 | inferred from direct assay polytene chromosome, telomeric region ; GO:0035012 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay chromatin ; GO:0000785 | inferred from sequence or structural similarity with Su(var)205 nucleolus ; GO:0005730 | inferred from direct assay polytene chromosome chromocenter ; GO:0005701 | inferred from direct assay" "CG15636, HP6, Umbrea, umbrea, UMB, UMBREA" "IPR000953:Chromo/chromo shadow domain, IPR008251:Chromo shadow domain, IPR016197:Chromo domain-like" CG15636 27-Aug-18 DroID_v2018_08 "Drer\cbx1a, Drer\cdyl, Drer\cbx5, Drer\cbx1b, Drer\cbx3b, Drer\cbx3a" - "Cele\hpl-1, Cele\hpl-2, Cele\set-31, Cele\H04D03.6" "Xtro\cbx5, Xtro\cbx1, Xtro\cbx3" "Mmus\Cbx1, Mmus\Cdyl, Mmus\Cbx3, Mmus\Cbx5, Mmus\Mphosph8, Mmus\Cdyl2" "Hsap\CBX5, Hsap\CDY2A, Hsap\CDY1B, Hsap\MPHOSPH8, Hsap\CDY1, Hsap\CBX3, Hsap\CDY2B, Hsap\CDYL, Hsap\CBX1, Hsap\CDYL2" "lethal - all die before end of embryonic stage,some die during embryonic stage,lethal,neuroanatomy defective,viable,visible" "eye,polytene chromosome, telomeric regionG61,embryonic/larval salivary gland,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum,polar body nucleus" FBgn0034705 CG11170 - http://flybase.org/reports/FBgn0034705 protein_coding_gene - regulation of signal transduction ; GO:0009966 | inferred from biological aspect of ancestor with PANTHER:PTN001279849 - "CG11170, CG30279" "IPR022049:FAM69, protein-kinase domain" CG11170 27-Aug-18 DroID_v2018_08 "Drer\si:ch73-147f11.1, Drer\dia1b, Drer\dia1a" - - Xtro\c3orf58 "Mmus\4930578C19Rik, Mmus\1190002N15Rik" "Hsap\CXorf36, Hsap\C3orf58" viable FBgn0084432 Su(dpp)YE12 Su(dpp)YE12 http://flybase.org/reports/FBgn0084432 gene - - - Su(dpp)YE12 - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,male sterile" FBgn0053373 5SrRNA:CR33373 5SrRNA:CR33373 http://flybase.org/reports/FBgn0053373 rRNA_gene structural constituent of ribosome ; GO:0003735 | inferred from sequence model translation ; GO:0006412 | inferred from sequence model cytosolic ribosome ; GO:0022626 | inferred from sequence model "CR33373, 5SrRNA:CR33373" - CR33373 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0025378 CG3795 - http://flybase.org/reports/FBgn0025378 FBgn0063223 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "EG:9D2.4, SP160, BcDNA:GH24985, CG3795" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG3795 27-Aug-18 DroID_v2018_08 "Drer\cfd, Drer\gzma, Drer\si:dkeyp-93a5.3, Drer\si:dkey-16l2.17, Drer\zgc:165423, Drer\zgc:163079, Drer\ovch1, Drer\si:ch211-165b19.5, Drer\si:ch211-165b19.9, Drer\si:ch211-165b19.8, Drer\zgc:92313, Drer\gzmk, Drer\LOC100004427, Drer\gzm3" - "Cele\try-1, Cele\try-6" - "Mmus\Klk15, Mmus\Klk9" "Hsap\KLK9, Hsap\KLK15" viable FBgn0026335 Su(tor)278-22 Su(tor)278-22 http://flybase.org/reports/FBgn0026335 - gene - - - Su(tor)278-22 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266426 Dfd::Scr Dfd::Scr http://flybase.org/reports/FBgn0266426 engineered_fusion_gene - - - "Dfd::Scr, Dfd[Scr]" - - 27-Aug-18 DroID_v2018_08 - - - - - - "embryonic mesothoracic segment,embryonic metathoracic segment,denticle,ectopic,cirri" FBgn0083294 E(smoDN)198 Enhancer of smoDN 198 http://flybase.org/reports/FBgn0083294 gene - - - E(smoDN)198 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0259446 C246 - http://flybase.org/reports/FBgn0259446 gene - - - C246 - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,lethal" "wing,chaeta" FBgn0263734 dco::Hsap\CSNK1E - http://flybase.org/reports/FBgn0263734 engineered_fusion_gene - - - "dco::Hsap\CSNK1E, ckIepsilon-dbt" - - 27-Aug-18 DroID_v2018_08 - - - - - - locomotor rhythm defective FBgn0052238 TTLL1B - http://flybase.org/reports/FBgn0052238 protein_coding_gene - protein polyglutamylation ; GO:0018095 | inferred from electronic annotation with InterPro:IPR027750 - "CG32238, CG7474" "IPR004344:Tubulin-tyrosine ligase/Tubulin polyglutamylase, IPR027750:Tubulin polyglutamylase TTLL1" CG32238 27-Aug-18 DroID_v2018_08 "Drer\ttll1, Drer\ttll2, Drer\ttll9, Drer\ttll5, Drer\ttll10, Drer\ttl" Scer\PBY1 "Cele\ttll-15, Cele\ttll-5, Cele\ttll-9, Cele\ttll-4" "Xtro\ttll2, Xtro\ttll3, Xtro\LOC100158544, Xtro\ttll5, Xtro\ttll1, Xtro\ttl" "Mmus\Ttll2, Mmus\Ttll3, Mmus\Ttll9, Mmus\Ttll10, Mmus\Ttll5, Mmus\Ttl, Mmus\Ttll1, Mmus\Ttll8" "Hsap\TTLL3, Hsap\TTLL5, Hsap\ARPC4-TTLL3, Hsap\TTLL9, Hsap\TTLL10, Hsap\TTLL8, Hsap\TTLL2, Hsap\TTL, Hsap\TTLL1" viable FBgn0265102 Oseg1 Outer segment 1 http://flybase.org/reports/FBgn0265102 protein_coding_gene molecular_function ; GO:0003674 | no biological data available protein localization to cilium ; GO:0061512 | inferred from biological aspect of ancestor with PANTHER:PTN000298746 intraciliary retrograde transport ; GO:0035721 | inferred from mutant phenotype non-motile cilium assembly ; GO:1905515 | inferred from mutant phenotype cilium assembly ; GO:0060271 | inferred from sequence model inferred from expression pattern intraciliary transport particle A ; GO:0030991 | inferred from sequence or structural similarity with HGNC:13556 non-motile cilium ; GO:0097730 | inferred from direct assay intraciliary transport particle A ; GO:0030991 | inferred from biological aspect of ancestor with PANTHER:PTN000298746 "Oseg1, IFT122, mecC, DAF-10, OSEG1, CG7161, oseg1, OSEG, OSM-4, Wdr10" "IPR011990:Tetratricopeptide-like helical domain, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat" CG7161 27-Aug-18 DroID_v2018_08 Drer\ift122 - Cele\daf-10 Xtro\ift122 "Mmus\Wdr19, Mmus\Ift122" "Hsap\IFT122, Hsap\IFT172" FBgn0065416 l(2)SH1541 lethal (2) SH1541 http://flybase.org/reports/FBgn0065416 gene - - - "l(2)SH1541, l(2)SH2 1541" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0266203 lncRNA:CR44898 - http://flybase.org/reports/FBgn0266203 non_protein_coding_gene - - - CR44898 - CR44898 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035016 CG4612 - http://flybase.org/reports/FBgn0035016 protein_coding_gene mRNA binding ; GO:0003729 | inferred from sequence or structural similarity poly(A) binding ; GO:0008143 | inferred from sequence or structural similarity with SGD:S000000967 positive regulation of translation ; GO:0045727 | inferred from direct assay long-term memory ; GO:0007616 | inferred from mutant phenotype - "cg4612, CG4612" IPR000504:RNA recognition motif domain CG4612 27-Aug-18 DroID_v2018_08 "Drer\eif4h, Drer\srsf10a, Drer\cirbpa, Drer\hnrnpaba, Drer\trnau1apb, Drer\trnau1apa, Drer\ncoa5, Drer\zgc:55733, Drer\rbm34, Drer\pabpc1b, Drer\zcrb1, Drer\hnrpdl, Drer\hnrnpa3, Drer\wu:fq32h04, Drer\hnrnpabb, Drer\pabpc1a, Drer\hnrnpd, Drer\hnrnpc, Drer\pabpc1l, Drer\dazl, Drer\hnrnpa1b, Drer\raly, Drer\pabpc4, Drer\eif4ba" "Scer\NGR1, Scer\PRP24, Scer\NOP12, Scer\NOP6, Scer\RIM4, Scer\MUD1, Scer\NSR1, Scer\NAB6, Scer\NAM8, Scer\CWC2, Scer\MRN1, Scer\PAB1" "Cele\K07H8.10, Cele\pab-1, Cele\sart-3, Cele\pab-2, Cele\R05D3.8" "Xtro\dazl, Xtro\hnrnpdl, Xtro\ralyl, Xtro\trnau1ap, Xtro\hnrnpa2b1, Xtro\cirbp, Xtro\pabpc4, Xtro\hnrnpab, Xtro\hnrnpa1, Xtro\pabpc1, Xtro\hnrnpd, Xtro\hnrnpc, Xtro\eif4h, Xtro\pabpc1l, Xtro\raly, Xtro\hnrnpa3, Xtro\eif4b, Xtro\rbm34" "Mmus\Gm21379, Mmus\Trnau1ap, Mmus\Boll, Mmus\Pabpc2, Mmus\Pabpc1, Mmus\Srsf10, Mmus\Hnrnpc, Mmus\Hnrnpa1, Mmus\Rbm34, Mmus\Slirp, Mmus\Hnrnpdl, Mmus\Srsf12, Mmus\Dazl, Mmus\Pabpc1l, Mmus\Cirbp, Mmus\Sart3, Mmus\Pabpc4, Mmus\Hnrnpa3, Mmus\Eif4h, Mmus\Pabpc6, Mmus\Raly, Mmus\Eif4b, Mmus\Rbm31y, Mmus\Hnrnpd, Mmus\Hnrnpab, Mmus\Hnrnpa2b1, Mmus\Tra2b, Mmus\Pabpc5, Mmus\Zcrb1, Mmus\Pabpc4l" "Hsap\DAZ4, Hsap\PABPC1L2A, Hsap\PABPC4L, Hsap\HNRNPA3, Hsap\HNRNPAB, Hsap\PABPC1, Hsap\PABPC1L, Hsap\RBM3, Hsap\DAZ1, Hsap\BOLL, Hsap\EIF4B, Hsap\PABPC5, Hsap\HNRNPA2B1, Hsap\HNRNPC, Hsap\SRSF10, Hsap\RALY, Hsap\HNRNPA1, Hsap\EIF4H, Hsap\CIRBP, Hsap\DAZL, Hsap\HNRNPCL1, Hsap\DAZ2, Hsap\PABPC4, Hsap\SART3, Hsap\RALYL, Hsap\RBM34, Hsap\HNRNPD, Hsap\PABPC1L2B, Hsap\HNRNPA1L2, Hsap\TRNAU1AP, Hsap\DAZ3, Hsap\SLIRP, Hsap\HNRNPDL, Hsap\PABPC3" visible wing FBgn0005146 l(2)DTS9 lethal (2) DTS9 http://flybase.org/reports/FBgn0005146 - gene - - - "DTS-L9, l(2)DTS9" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,dominant,heat sensitive,recessive" FBgn0020844 l(2)21Ba1 lethal (2) 21Ba1 http://flybase.org/reports/FBgn0020844 - gene - - - "21Ba1, l(2)21Ba1" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065940 l(2)SH0116 lethal (2) SH0116 http://flybase.org/reports/FBgn0065940 gene - - - l(2)SH0116 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0083075 ms(3)236 ms(3)236 http://flybase.org/reports/FBgn0083075 gene - - - ms(3)236 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0042147 CG18824 - http://flybase.org/reports/FBgn0042147 protein_coding_gene - - - CG18824 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0027609 morgue "modifier of rpr and grim, ubiquitously expressed" http://flybase.org/reports/FBgn0027609 - protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model K48-linked polyubiquitin binding ; GO:0036435 | inferred from direct assay regulation of retinal cell programmed cell death ; GO:0046668 | non-traceable author statement SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from mutant phenotype positive regulation of compound eye retinal cell apoptotic process ; GO:1901694 | inferred from mutant phenotype inferred from genetic interaction with Diap1 SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | non-traceable author statement "CG15437, BcDNA:GH02435, morgue, Morgue, FBXO18" "IPR000608:Ubiquitin-conjugating enzyme E2, IPR001810:F-box domain, IPR016135:Ubiquitin-conjugating enzyme/RWD-like" CG15437 27-Aug-18 DroID_v2018_08 "Drer\ube2e2, Drer\ube2d3, Drer\ube2t, Drer\ube2d4, Drer\ube2d2, Drer\ube2na, Drer\ube2d2l, Drer\ube2d1a, Drer\ube2e3, Drer\ube2e1, Drer\ube2d1b, Drer\ube2nb" "Scer\UBC13, Scer\UBC5, Scer\UBC4, Scer\PEX4" "Cele\let-70, Cele\uev-2" "Xtro\ube2d4, Xtro\ube2e3, Xtro\ube2e2, Xtro\ube2d1, Xtro\ube2d3, Xtro\ube2e1, Xtro\ube2n" "Mmus\Ube2e1, Mmus\Ube2dnl2, Mmus\Ube2d3, Mmus\Ube2d2b, Mmus\Ube2t, Mmus\Ube2dnl1, Mmus\Ube2n, Mmus\Ube2d1, Mmus\Ube2d2a, Mmus\Ube2e3, Mmus\Ube2e2" "Hsap\UBE2NL, Hsap\UBE2E1, Hsap\UBE2N, Hsap\UBE2D3, Hsap\UBE2T, Hsap\UBE2E3, Hsap\UBE2D2, Hsap\UBE2D1, Hsap\UBE2E2, Hsap\UBE2D4" " embryonic stage -- adult stage , pupal stage--adult stage , pupal stage " " organism

, primary pigment cell

, tertiary pigment cell

, secondary pigment cell

" "viable,hypoactive,visible,decreased cell death,recessive,partially lethal - majority die,melanotic mass phenotype,lethal,some die during third instar larval stage,some die during pupal stage,partially lethal" "anterior pupal spiracle,tergite,midline glial cell,supernumerary,pigment cell,chaeta,leg,melanotic mass,embryonic peripheral glial cell 10,support cell of the dorsal bipolar dendritic cell" DRSC00264 I 0.578050001 -1.543783132 0.284723587 0.115384271 -0.532947828 -0.51377844 FBgn0046709 GIIIC GIIIC http://flybase.org/reports/FBgn0046709 gene phospholipase A2 activity ; GO:0004623 | non-traceable author statement - extracellular region ; GO:0005576 | non-traceable author statement "dGIIIC, GIIIC" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0038504 Sur-8 Sur-8 http://flybase.org/reports/FBgn0038504 protein_coding_gene protein phosphatase regulator activity ; GO:0019888 | inferred from biological aspect of ancestor with PANTHER:PTN002351899 protein phosphatase binding ; GO:0019903 | inferred from biological aspect of ancestor with PANTHER:PTN002351899 positive regulation of ERK1 and ERK2 cascade ; GO:0070374 | inferred from genetic interaction with Ras85D positive regulation of Ras protein signal transduction ; GO:0046579 | inferred from genetic interaction with Ras85D protein phosphatase type 1 complex ; GO:0000164 | inferred from biological aspect of ancestor with PANTHER:PTN001504428 "Sur8, SUR-8, CT17146, CG5407, Sur-8" "IPR001611:Leucine-rich repeat, IPR003591:Leucine-rich repeat, typical subtype, IPR032675:Leucine-rich repeat domain, L domain-like, IPR026906:Leucine rich repeat 5" CG5407 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-106h11.1, Drer\shoc2" Scer\CYR1 "Cele\F43C1.1, Cele\ZK546.2, Cele\soc-2" Xtro\shoc2 "Mmus\Lrrd1, Mmus\Phlpp2, Mmus\Shoc2, Mmus\Phlpp1" "Hsap\PHLPP2, Hsap\SHOC2, Hsap\PHLPP1" viable FBgn0085193 CG34164 - http://flybase.org/reports/FBgn0085193 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34164 - CG34164 27-Aug-18 DroID_v2018_08 "Drer\rpl7l1, Drer\rpl7" "Scer\RLP7, Scer\RPL7B, Scer\RPL7A" - Xtro\rpl7 "Mmus\Npsr1, Mmus\Rpl7, Mmus\Rpl7l1" "Hsap\NPSR1, Hsap\RPL7L1, Hsap\RPL7" FBgn0005751 l(1)TK305 lethal (1) TK305 http://flybase.org/reports/FBgn0005751 - gene - - - "l305, l(1)TK305" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0086907 Cyt-c-d Cytochrome c distal http://flybase.org/reports/FBgn0086907 protein_coding_gene "heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR002327, InterPro:IPR009056 electron carrier activity ; GO:0009055 | inferred from direct assay" "mitochondrial electron transport, cytochrome c to oxygen ; GO:0006123 | inferred from biological aspect of ancestor with PANTHER:PTN000238899 sperm individualization ; GO:0007291 | inferred from mutant phenotype regulation of compound eye retinal cell programmed cell death ; GO:0046669 | inferred from mutant phenotype activation of cysteine-type endopeptidase activity involved in apoptotic process ; GO:0006919 | inferred from mutant phenotype mitochondrial electron transport, ubiquinol to cytochrome c ; GO:0006122 | inferred from biological aspect of ancestor with PANTHER:PTN000238899 oxidative phosphorylation ; GO:0006119 | inferred from sequence or structural similarity with SGD:S000003809" mitochondrial inner membrane ; GO:0005743 | inferred from sequence or structural similarity with SGD:S000003809 mitochondrion ; GO:0005739 | inferred from direct assay cytosol ; GO:0005829 | inferred from direct assay mitochondrial intermembrane space ; GO:0005758 | inferred from biological aspect of ancestor with PANTHER:PTN000238899 "CG13263, cyt-c-d, cytochrome c, bln, Cytc, bs30f07.y1, cyt.c, DC3, CytC1, pDMc02, CytC-1, Cyt-c1, ms(2)04445, Cyt-c-d, Cytc-d, dc3, cyt c-d, cyt c, Cyt c, CytC, Cyt C, CYC, cyt.c-d" "IPR002327:Cytochrome c, class IA/ IB, IPR009056:Cytochrome c-like domain" CG13263 27-Aug-18 DroID_v2018_08 Drer\cycsb "Scer\CYC7, Scer\CYC1" "Cele\cyc-2.2, Cele\cyc-2.1" "Xtro\cyct, Xtro\cycs" "Mmus\Cycs, Mmus\Cyct" Hsap\CYCS " adult stage , larval stage--adult stage " " adult abdomen

, adult thorax

, adult head

" FBgn0002722 m(Est-6) modifier of Esterase 6 http://flybase.org/reports/FBgn0002722 - gene - - - "m-est, M-est, m(Est-6), m(Est6)" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036534 DCP2 Decapping protein 2 http://flybase.org/reports/FBgn0036534 protein_coding_gene RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR007722 manganese ion binding ; GO:0030145 | inferred from electronic annotation with InterPro:IPR007722 m7G(5')pppN diphosphatase activity ; GO:0050072 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VKK1 protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VVI2 "gene silencing by miRNA ; GO:0035195 | inferred from mutant phenotype nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ; GO:0000184 | NOT inferred from mutant phenotype regulation of cytoplasmic mRNA processing body assembly ; GO:0010603 | inferred from mutant phenotype nuclear-transcribed mRNA catabolic process ; GO:0000956 | inferred from mutant phenotype deadenylation-dependent decapping of nuclear-transcribed mRNA ; GO:0000290 | inferred from direct assay" cytoplasmic mRNA processing body ; GO:0000932 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "LD07107, BEST:LD07107, dDcp2, DCP2, CG6169, DCp2p, dcp2, dDcp, dDCP2, Dcp2" "IPR000086:NUDIX hydrolase domain, IPR007722:mRNA decapping protein 2, Box A domain, IPR015797:NUDIX hydrolase domain-like, IPR020084:NUDIX hydrolase, conserved site" CG6169 27-Aug-18 DroID_v2018_08 Drer\dcp2 Scer\DCP2 Cele\dcap-2 Xtro\dcp2 Mmus\Dcp2 Hsap\DCP2 "lethal - all die before end of pupal stage,some die during pupal stage,lethal - all die before end of second instar larval stage,lethal" cytoplasmic mRNA processing body | germline clone DRSC10597 EK -0.508309891 -0.117026778 -2.84195425 -3.90546502 2.911549358 2.172683374 FBgn0032731 Swip-1 Swiprosin-1 http://flybase.org/reports/FBgn0032731 protein_coding_gene calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048 mesoderm development ; GO:0007498 | inferred from expression pattern plasma membrane ; GO:0005886 | inferred from direct assay muscle tendon junction ; GO:0005927 | inferred from direct assay "CG10641, Swip-1, DSwip-1, EFhd2, efhd2, efhd" "IPR002048:EF-hand domain, IPR011992:EF-hand domain pair, IPR018247:EF-Hand 1, calcium-binding site" CG10641 27-Aug-18 DroID_v2018_08 "Drer\efhd2, Drer\efhd1" - Cele\efhd-1 "Xtro\efhd2, Xtro\efhd1" "Mmus\Efhd2, Mmus\Efhd1" "Hsap\EFHD2, Hsap\EFHD1" "visible,partially lethal - majority die,some die during pharate adult stage,viable,fertile" mesothoracic tergum FBgn0011165 l(1)DM-2 lethal (1) DM-2 http://flybase.org/reports/FBgn0011165 FBgn0010204 gene - - - l(1)DM-2 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0262077 JC09 - http://flybase.org/reports/FBgn0262077 gene - response to anesthetic ; GO:0072347 | inferred from mutant phenotype - JC09 - - 27-Aug-18 DroID_v2018_08 - - - - - - "chemical sensitive,recessive" FBgn0000724 fr fringed http://flybase.org/reports/FBgn0000724 - gene - - - fr - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,heat sensitive,viable,reduced,female semi-sterile,female sterile,poor,male sterile" "wing,dorsal row,ventral row,adult abdomen,eye,macrochaeta" FBgn0028249 l(3)93Bj lethal (3) 93Bj http://flybase.org/reports/FBgn0028249 gene - - - l(3)93Bj - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0039420 CG6154 - http://flybase.org/reports/FBgn0039420 protein_coding_gene dipeptidase activity ; GO:0016805 | inferred from biological aspect of ancestor with PANTHER:PTN000047764 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR008257 - CG6154 "IPR008257:Renal dipeptidase family, IPR032466:Metal-dependent hydrolase" CG6154 27-Aug-18 DroID_v2018_08 "Drer\dpep1, Drer\dpep2" - Cele\math-31 "Xtro\dpep1, Xtro\dpep2" "Mmus\Dpep3, Mmus\Dpep2, Mmus\Dpep1" "Hsap\DPEP1, Hsap\DPEP3, Hsap\DPEP2" viable FBgn0085552 CG41010 - http://flybase.org/reports/FBgn0085552 protein_coding_gene - - - CG41010 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263747 CG43672 - http://flybase.org/reports/FBgn0263747 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from biological aspect of ancestor with PANTHER:PTN000442469 ATPase activity, coupled to transmembrane movement of substances ; GO:0042626 | inferred from sequence or structural similarity with UniProtKB:O94911" lipid transport ; GO:0006869 | inferred from biological aspect of ancestor with PANTHER:PTN000442469 transport ; GO:0006810 | inferred from sequence or structural similarity with UniProtKB:O94911 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with UniProtKB:Q9BZC7 intracellular membrane-bounded organelle ; GO:0043231 | inferred from biological aspect of ancestor with PANTHER:PTN000442469 "CG43672, CG8473, CG33173" "IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR026082:ABC transporter A, ABCA" CG43672 27-Aug-18 DroID_v2018_08 "Drer\abca3b, Drer\abca12, Drer\abca1b, Drer\abca5, Drer\abch1, Drer\abca1a, Drer\abca2" - "Cele\abt-2, Cele\abt-1" "Xtro\abca9, Xtro\abca8, Xtro\abca1, Xtro\abca10, Xtro\abca4, Xtro\abca2, Xtro\abca3" "Mmus\Abca13, Mmus\Abca5, Mmus\Abca9, Mmus\Abca8b, Mmus\Abca8a, Mmus\Abca16, Mmus\Abca1, Mmus\Abca2, Mmus\Abca12, Mmus\Abca3, Mmus\Abca17, Mmus\Abca4, Mmus\Abca7, Mmus\Abca14, Mmus\Abca15, Mmus\Abca6" "Hsap\ABCA9, Hsap\ABCA4, Hsap\ABCA1, Hsap\ABCA13, Hsap\ABCA10, Hsap\ABCA8, Hsap\ABCA2, Hsap\ABCA6, Hsap\ABCA3, Hsap\ABCA5, Hsap\ABCA7, Hsap\ABCA12" "partially lethal - majority die,some die during pupal stage,viable,visible" "chaeta,supernumerary" FBgn0032748 CG10492 - http://flybase.org/reports/FBgn0032748 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001878 nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001878 - - "TuB1, TU37B1, B1, anon-37B-1, CG10492" "IPR001878:Zinc finger, CCHC-type" CG10492 27-Aug-18 DroID_v2018_08 "Drer\zcchc14, Drer\zcchc2" - Cele\gls-1 Xtro\zcchc2 "Mmus\Zcchc2, Mmus\Zcchc14" "Hsap\ZCCHC14, Hsap\ZCCHC2" "viable,fertile,visible,body color defective,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0038575 CG7208 - http://flybase.org/reports/FBgn0038575 protein_coding_gene - - - "CG7208, CG 7208" IPR031961:Domain of unknown function DUF4780 CG7208 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0028916 CG33090 - http://flybase.org/reports/FBgn0028916 protein_coding_gene beta-glucosidase activity ; GO:0008422 | inferred from sequence or structural similarity with UniProtKB:Q9HCG7 glycoside catabolic process ; GO:0016139 | inferred from sequence or structural similarity with UniProtKB:Q9HCG7 bile acid metabolic process ; GO:0008206 | inferred from sequence or structural similarity with UniProtKB:Q9HCG7 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with UniProtKB:Q9HCG7 "BG:DS01068.2, CG7469, CG31837, CG15287, CG33090" "IPR008928:Six-hairpin glycosidase-like, IPR024462:Glycosyl-hydrolase family 116, N-terminal, IPR006775:Glycosyl-hydrolase family 116, catalytic region" CG33090 27-Aug-18 DroID_v2018_08 Drer\gba2 - "Cele\hpo-13, Cele\R08F11.1" Xtro\gba2 Mmus\Gba2 Hsap\GBA2 "viable,fertile,male" FBgn0041736 l(3)63Eg lethal (3) 63Eg http://flybase.org/reports/FBgn0041736 gene - - - "group III, l(3)63Eg" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0037703 JHDM2 JmjC domain-containing histone demethylase 2 http://flybase.org/reports/FBgn0037703 protein_coding_gene chromatin DNA binding ; GO:0031490 | inferred from biological aspect of ancestor with PANTHER:PTN000284569 histone demethylase activity (H3-K9 specific) ; GO:0032454 | inferred from mutant phenotype transcription regulatory region sequence-specific DNA binding ; GO:0000976 | inferred from biological aspect of ancestor with PANTHER:PTN000284569 histone demethylase activity ; GO:0032452 | inferred from sequence model histone demethylation ; GO:0016577 | inferred from sequence model histone H3-K9 demethylation ; GO:0033169 | inferred from mutant phenotype positive regulation of chromatin silencing ; GO:0031937 | inferred from mutant phenotype regulation of response to DNA damage stimulus ; GO:2001020 | inferred from genetic interaction with lok nucleus ; GO:0005634 | inferred from sequence model nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000284569 chromatin ; GO:0000785 | inferred from direct assay "CG31123, CG8165, JHDM2" IPR003347:JmjC domain CG8165 27-Aug-18 DroID_v2018_08 "Drer\kdm3b, Drer\jmjd1cb, Drer\jmjd1ca" - "Cele\R10E8.3, Cele\C05C12.5, Cele\C01B9.1, Cele\fbxa-134, Cele\F57G4.1, Cele\R10E8.2" "Xtro\jmjd1c, Xtro\kdm3b, Xtro\kdm3a" "Mmus\Kdm3a, Mmus\Kdm3b, Mmus\Jmjd1c, Mmus\Hr" "Hsap\KDM3A, Hsap\KDM3B, Hsap\JMJD1C, Hsap\HR" "viable,fertile" FBgn0000287 salr spalt-related http://flybase.org/reports/FBgn0000287 - protein_coding_gene "transcription regulatory region DNA binding ; GO:0044212 | inferred from biological aspect of ancestor with PANTHER:PTN000579295 RNA polymerase II regulatory region sequence-specific DNA binding ; GO:0000977 | inferred from sequence or structural similarity with WB:WBGene00004773 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from biological aspect of ancestor with PANTHER:PTN000579295 sequence-specific DNA binding ; GO:0043565 | inferred from biological aspect of ancestor with PANTHER:PTN000579295" "regulation of transcription, DNA-templated ; GO:0006355 | inferred from biological aspect of ancestor with PANTHER:PTN000579295 antennal joint development ; GO:0048098 | inferred from mutant phenotype imaginal disc-derived wing vein morphogenesis ; GO:0008586 | traceable author statement signal transduction ; GO:0007165 | inferred from biological aspect of ancestor with PANTHER:PTN000579295 male genitalia development ; GO:0030539 | inferred from mutant phenotype sensory perception of sound ; GO:0007605 | inferred from mutant phenotype sensory organ development ; GO:0007423 | inferred from mutant phenotype negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from sequence or structural similarity with WB:WBGene00004773 sensory perception of sound ; GO:0007605 | inferred from genetic interaction with salm neurogenesis ; GO:0022008 | inferred from mutant phenotype male gonad development ; GO:0008584 | inferred from mutant phenotype transcription from RNA polymerase II promoter ; GO:0006366 | inferred from biological aspect of ancestor with PANTHER:PTN000579295" nucleus ; GO:0005634 | inferred from sequence or structural similarity with WB:WBGene00004773 nucleus ; GO:0005634 | inferred from direct assay "spalt, sal, Spalt, sal-r, Sal-r, salR, 32F, Cf3, CG4881, salr, Salr" IPR013087:Zinc finger C2H2-type CG4881 27-Aug-18 DroID_v2018_08 "Drer\znf1004, Drer\sall3b, Drer\znf219, Drer\znf526, Drer\znf217, Drer\rreb1a, Drer\znf536, Drer\sall3a, Drer\sall2, Drer\si:ch211-212k18.5, Drer\sall1a, Drer\znf516, Drer\sall4, Drer\rreb1b, Drer\znf983, Drer\si:ch211-202h22.10, Drer\znf1010, Drer\LOC100537687, Drer\si:ch211-266d19.4" - "Cele\sem-4, Cele\Y48G8AL.10" "Xtro\znf568, Xtro\znf236, Xtro\sall3, Xtro\sall2, Xtro\znf208, Xtro\sall1, Xtro\sall4" "Mmus\Rbak, Mmus\Zfp235, Mmus\Zfp236, Mmus\Zfp458, Mmus\Sall1, Mmus\Zfp229, Mmus\Zfp74, Mmus\Zfp560, Mmus\Zfp182, Mmus\Rreb1, Mmus\Gm14432, Mmus\Sall2, Mmus\Zfp808, Mmus\Zfp27, Mmus\Zfp334, Mmus\Zfp217, Mmus\Zfp619, Mmus\Zfp536, Mmus\Zfp62, Mmus\Gm14124, Mmus\Zfp26, Mmus\Zfp516, Mmus\Zfp219, Mmus\Sall3, Mmus\Zfp709, Mmus\Sall4" "Hsap\ZNF268, Hsap\SALL4, Hsap\ZNF433, Hsap\ZNF585B, Hsap\SALL3, Hsap\ZNF775, Hsap\ZNF721, Hsap\ZNF699, Hsap\ZNF709, Hsap\ZNF717, Hsap\ZNF160, Hsap\ZNF536, Hsap\SALL2, Hsap\ZNF236, Hsap\ZNF227, Hsap\ZNF761, Hsap\ZNF234, Hsap\ZNF135, Hsap\ZNF226, Hsap\ZNF251, Hsap\ZNF107, Hsap\ZNF443, Hsap\ZNF182, Hsap\ZNF91, Hsap\ZFP62, Hsap\ZNF229, Hsap\ZNF516, Hsap\ZNF850, Hsap\ZNF217, Hsap\ZNF585A, Hsap\ZNF836, Hsap\HKR1, Hsap\RREB1, Hsap\ZNF235, Hsap\ZNF574, Hsap\SALL1, Hsap\ZNF337, Hsap\ZNF845, Hsap\ZNF219" " embryonic stage -- adult stage , larval stage | third instar " dorsal mesothoracic disc | restricted

" embryonic stage | stage 16 , embryonic stage | late , larval stage , larval stage | third instar " " embryonic/larval posterior spiracle

, embryonic central nervous system

, larval central nervous system

, dorsal mesothoracic disc | dorsal comparment & medial

, imaginal disc

, dorsal mesothoracic disc | restricted

" "visible,lethal,neuroanatomy defective,partially lethal - majority die,some die during pupal stage" "macrochaeta,ectopic,anterior dorsocentral bristle,anterior postalar bristle,precursor,posterior postalar bristle,anterior notopleural bristle,posterior notopleural bristle,dorsocentral bristle,notopleural bristle,postalar bristle,wing vein L2,wing vein L5,posterior dorsocentral bristle,posterior scutellar bristle,adult thorax & macrochaetaBx-MS1096,embryonic/larval neuroblast,ganglion mother cell,trichogen cell,mesothoracic tergum,wing vein,wing" FBgn0002891 mus205 mutagen-sensitive 205 http://flybase.org/reports/FBgn0002891 FBgn0033223 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR006134 nucleotide binding ; GO:0000166 | inferred from electronic annotation with InterPro:IPR006134, InterPro:IPR006172, InterPro:IPR017964 3'-5' exonuclease activity ; GO:0008408 | NOT inferred from direct assay DNA-directed DNA polymerase activity ; GO:0003887 | inferred from direct assay" translesion synthesis ; GO:0019985 | non-traceable author statement double-strand break repair via homologous recombination ; GO:0000724 | inferred from mutant phenotype error-prone translesion synthesis ; GO:0042276 | inferred from biological aspect of ancestor with PANTHER:PTN000035411 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000035347 zeta DNA polymerase complex ; GO:0016035 | inferred from biological aspect of ancestor with PANTHER:PTN000035411 "154926_at, Dmpolzeta, CG1925, AAF59191, DmREV3, DhRev3, mus 205, mus-205, mus(2)205, mus205, Mus205, rev3" "IPR017964:DNA-directed DNA polymerase, family B, conserved site, IPR025687:C4-type zinc-finger of DNA polymerase delta, IPR006134:DNA-directed DNA polymerase, family B, multifunctional domain, IPR006172:DNA-directed DNA polymerase, family B, IPR012337:Ribonuclease H-like domain, IPR006133:DNA-directed DNA polymerase, family B, exonuclease domain, IPR023211:DNA polymerase, palm domain" CG1925 27-Aug-18 DroID_v2018_08 "Drer\pold1, Drer\si:ch211-134n22.1, Drer\si:dkey-114c15.7, Drer\rev3l" Scer\REV3 Cele\Y37B11A.2 "Xtro\pold1, Xtro\rev3l" "Mmus\Rev3l, Mmus\C77370, Mmus\Pold1" "Hsap\REV3L, Hsap\KIAA2022, Hsap\POLD1" "chemical sensitive,radiation sensitive,DNA repair defective,recessive,viable,radiation resistant,fertile,maternal effect,female fertile,reduced" FBgn0014202 l(1)16Fi lethal (1) 16Fi http://flybase.org/reports/FBgn0014202 - gene - - - l(1)16Fi - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,polyphasic,recessive" FBgn0004026 wtl weltlike http://flybase.org/reports/FBgn0004026 - gene - - - wtl - - 27-Aug-18 DroID_v2018_08 - - - - - - female sterile "eye,arista,wing" FBgn0082343 HM515 HM515 http://flybase.org/reports/FBgn0082343 gene - - - HM515 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0023507 D2hgdh D-2-hydroxyglutaric acid dehydrogenase http://flybase.org/reports/FBgn0023507 - protein_coding_gene FAD binding ; GO:0071949 | inferred from biological aspect of ancestor with PANTHER:PTN001714811 (R)-2-hydroxyglutarate dehydrogenase activity ; GO:0051990 | inferred from mutant phenotype D-lactate dehydrogenase (cytochrome) activity ; GO:0004458 | inferred from biological aspect of ancestor with PANTHER:PTN001714811 lactate oxidation ; GO:0019516 | inferred from biological aspect of ancestor with PANTHER:PTN001714811 respiratory electron transport chain ; GO:0022904 | inferred from biological aspect of ancestor with PANTHER:PTN001714811 oxidation-reduction process ; GO:0055114 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from biological aspect of ancestor with PANTHER:PTN000202300 "EG87B1, EG:87B1.3, CG3835, D2hgdh, D2HGDH" "IPR004113:FAD-linked oxidase, C-terminal, IPR006094:FAD linked oxidase, N-terminal, IPR016164:FAD-linked oxidase-like, C-terminal, IPR016166:FAD-binding, type 2, IPR016167:FAD-binding, type 2, subdomain 1, IPR016169:CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2, IPR016171:Vanillyl-alcohol oxidase, C-terminal subdomain 2" CG3835 27-Aug-18 DroID_v2018_08 Drer\d2hgdh "Scer\DLD1, Scer\DLD3, Scer\DLD2" Cele\F54D5.12 Xtro\d2hgdh "Mmus\Ldhd, Mmus\D2hgdh" "Hsap\D2HGDH, Hsap\LDHD" "partially lethal - majority die,some die during pupal stage" FBgn0065710 l(2)SH0598 lethal (2) SH0598 http://flybase.org/reports/FBgn0065710 gene - - - "l(2)SH0598, l(2)SH2 0598" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0035791 CG8539 - http://flybase.org/reports/FBgn0035791 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000834 metallocarboxypeptidase activity ; GO:0004181 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000834 extracellular space ; GO:0005615 | inferred from biological aspect of ancestor with PANTHER:PTN000194073 CG8539 "IPR000834:Peptidase M14, carboxypeptidase A, IPR034223:Insect gut carboxypeptidase-like, carboxypeptidase domain" CG8539 27-Aug-18 DroID_v2018_08 "Drer\cpo, Drer\cpa4, Drer\cpa6, Drer\cpb2, Drer\cpa2, Drer\cpa5, Drer\cpb1, Drer\cpa1" Scer\ECM14 "Cele\suro-1, Cele\W01A8.6, Cele\T06A4.3, Cele\Y47G6A.19, Cele\T06A4.1, Cele\F02D8.4, Cele\Y18H1A.9, Cele\Y59C2A.1, Cele\ZC434.9" "Xtro\cpo, Xtro\cpa1, Xtro\cpb2, Xtro\cpb1, Xtro\cpa3" "Mmus\Cpa3, Mmus\Cpa1, Mmus\Cpa5, Mmus\Cpa2, Mmus\Cpa6, Mmus\Cpb1, Mmus\Cpb2, Mmus\Cpa4" "Hsap\CPA6, Hsap\CPO, Hsap\CPA5, Hsap\CPB1, Hsap\CPA1, Hsap\CPA2, Hsap\CPA4, Hsap\CPA3, Hsap\CPB2" FBgn0061482 rover\pol rover element pol http://flybase.org/reports/FBgn0061482 transposable_element_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR012337 DNA integration ; GO:0015074 | inferred from electronic annotation with InterPro:IPR001584 - rover\pol "IPR021109:Aspartic peptidase domain, IPR000477:Reverse transcriptase domain, IPR001584:Integrase, catalytic core, IPR012337:Ribonuclease H-like domain" - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0069086 sah sahnehaeubchen http://flybase.org/reports/FBgn0069086 gene molecular_function ; GO:0003674 | no biological data available oocyte dorsal/ventral axis specification ; GO:0007310 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available sah - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,germline clone,non-rescuable maternal effect,recessive,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" chorion | germline clone | maternal effect FBgn0001057 Fs(3)Kev Female sterile (3) Keve http://flybase.org/reports/FBgn0001057 - gene - - - "Fs(3)Keve, Fs(3)Sz16, Fs(3)Kev" - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,dominant,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" FBgn0266943 lncRNA:CR45394 - http://flybase.org/reports/FBgn0266943 non_protein_coding_gene - - - CR45394 - CR45394 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260770 CG42568 - http://flybase.org/reports/FBgn0260770 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG42568, CG13571, CG12240" - CG42568 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0062696 EP1191 EP1191 http://flybase.org/reports/FBgn0062696 gene - - - "EP(3)1191, EP1191" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031857 LUBEL Linear Ubiquitin E3 ligase http://flybase.org/reports/FBgn0031857 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841, InterPro:IPR001876 K63-linked polyubiquitin binding ; GO:0070530 | inferred from direct assay K48-linked polyubiquitin binding ; GO:0036435 | inferred from direct assay ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:16031 ubiquitin protein ligase activity ; GO:0061630 | inferred from direct assay linear polyubiquitin binding ; GO:1990450 | inferred from direct assay zinc ion binding ; GO:0008270 | inferred from sequence model" protein polyubiquitination ; GO:0000209 | inferred from sequence or structural similarity with HGNC:16031 protein linear polyubiquitination ; GO:0097039 | inferred from direct assay heat acclimation ; GO:0010286 | inferred from mutant phenotype LUBAC complex ; GO:0071797 | inferred from electronic annotation with InterPro:IPR026254 cellular_component ; GO:0005575 | no biological data available "AAF52435.2, LUBEL, CG11321" "IPR001876:Zinc finger, RanBP2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR026254:E3 ubiquitin-protein ligase RNF31, IPR001841:Zinc finger, RING-type, IPR002867:IBR domain, IPR032065:E3 ubiquitin-protein ligase RNF31, UB-associated-like domain" CG11321 27-Aug-18 DroID_v2018_08 "Drer\LOC100334178, Drer\si:dkey-181m9.8, Drer\rnf216" - - "Xtro\rnf31, Xtro\rnf216" "Mmus\Rnf216, Mmus\Rnf31" "Hsap\RNF31, Hsap\RNF216" viable FBgn0266707 lncRNA:CR45197 - http://flybase.org/reports/FBgn0266707 non_protein_coding_gene - - - CR45197 - CR45197 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266213 lncRNA:CR44908 - http://flybase.org/reports/FBgn0266213 non_protein_coding_gene - - - CR44908 - CR44908 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085495 CG40534 - http://flybase.org/reports/FBgn0085495 protein_coding_gene - - - CG40534 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004772 l(3)91Ca lethal (3) 91Ca http://flybase.org/reports/FBgn0004772 - gene - - - "l(3)CR1, l(3)91Ca" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0024222 IKKbeta I-kappaB kinase beta http://flybase.org/reports/FBgn0024222 "FBgn0028725, FBgn0028726, FBgn0029099, FBgn0029160" protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719 protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9GYV5 protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity IkappaB kinase activity ; GO:0008384 | inferred from direct assay IkappaB kinase activity ; GO:0008384 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000540281 protein kinase activity ; GO:0004672 | non-traceable author statement protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q03017 regulation of innate immune response ; GO:0045088 | inferred from mutant phenotype positive regulation of defense response to virus by host ; GO:0002230 | inferred from mutant phenotype positive regulation of antibacterial peptide biosynthetic process ; GO:0006963 | inferred from mutant phenotype positive regulation of NF-kappaB transcription factor activity ; GO:0051092 | inferred from biological aspect of ancestor with PANTHER:PTN000540281 positive regulation of antibacterial peptide biosynthetic process ; GO:0006963 | inferred from direct assay positive regulation of antibacterial peptide biosynthetic process ; GO:0006963 | non-traceable author statement protein phosphorylation ; GO:0006468 | non-traceable author statement protein catabolic process ; GO:0030163 | inferred from direct assay I-kappaB phosphorylation ; GO:0007252 | inferred from direct assay peptidyl-serine phosphorylation ; GO:0018105 | inferred from direct assay antibacterial humoral response ; GO:0019731 | inferred from mutant phenotype Toll signaling pathway ; GO:0008063 | traceable author statement positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from biological aspect of ancestor with PANTHER:PTN000540281 anatomical structure morphogenesis ; GO:0009653 | inferred from biological aspect of ancestor with PANTHER:PTN000540281 defense response to virus ; GO:0051607 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype tumor necrosis factor-mediated signaling pathway ; GO:0033209 | inferred from biological aspect of ancestor with PANTHER:PTN000540281 peptidoglycan recognition protein signaling pathway ; GO:0061057 | inferred from mutant phenotype IkappaB kinase complex ; GO:0008385 | inferred from biological aspect of ancestor with PANTHER:PTN000540281 cytoplasm ; GO:0005737 | inferred from direct assay "ird, dIKK-beta, IKK, IKK-beta, dIKK, IKKB, DmIKKb, DmIkkbeta, dmIKKbeta, ird5/DmIkk[beta], DmIKKbeta, CG4201, DmIKK, Dmikkbeta, DmIKKBeta, dLak, Ird-5, Ik, ikk, LRK, DLAK, DIK, anon-89Bd, Lak, IK, dIKKbeta, IKKbeta, IKKb, Ird5, ird5, IRD-5, IRD5, Ikkbeta, Dmikkb, ird-5, Ikkb, ird[5]" "IPR000719:Protein kinase domain, IPR008271:Serine/threonine-protein kinase, active site, IPR011009:Protein kinase-like domain" CG4201 27-Aug-18 DroID_v2018_08 "Drer\chuk, Drer\ikbke, Drer\ikbkb, Drer\tbk1" - - "Xtro\LOC101732839, Xtro\chuk, Xtro\ikbkb, Xtro\tbk1" "Mmus\Ikbke, Mmus\Tbk1, Mmus\Ikbkb, Mmus\Chuk" "Hsap\IKBKB, Hsap\IKBKE, Hsap\CHUK, Hsap\ERLIN1, Hsap\TBK1" embryonic stage -- adult stage "immune response defective,viable,fertile,recessive,partially lethal - majority die" FBgn0000981 fs(2)HO294 female sterile (2) HO294 http://flybase.org/reports/FBgn0000981 - gene - - - "fs(2)294A, fs(2)HO294" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005083 fs(2)OW807 female sterile (2) OW807 http://flybase.org/reports/FBgn0005083 - gene - - - fs(2)OW807 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005057 fs(2)OW103 female sterile (2) OW103 http://flybase.org/reports/FBgn0005057 - gene - - - fs(2)OW103 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0086519 Cpr47Eg Cuticular protein 47Eg http://flybase.org/reports/FBgn0086519 protein_coding_gene structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model structural constituent of cuticle ; GO:0042302 | inferred from biological aspect of ancestor with PANTHER:PTN000822475 chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Lcp2a, BcDNA:RE09259, CG9070, Cpr47Eg, Cpr47eg" "IPR000618:Insect cuticle protein, IPR031305:Casein alpha/beta, conserved site" CG9070 27-Aug-18 DroID_v2018_08 Drer\LOC100003040 - "Cele\math-34, Cele\F44F1.4, Cele\sdz-30" - "Mmus\H2-K1, Mmus\2410137M14Rik" - viable FBgn0033442 CG1690 - http://flybase.org/reports/FBgn0033442 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG1690 - CG1690 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC06636 I 1.675317898 1.408913124 -0.268452981 1.010431759 0.164064832 0.337068218 FBgn0043852 vizhichai vizhichai http://flybase.org/reports/FBgn0043852 gene - - - vizhichai - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031115 CG11710 - http://flybase.org/reports/FBgn0031115 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR009349 transcription coactivator activity ; GO:0003713 | inferred from biological aspect of ancestor with PANTHER:PTN000311349 "positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from biological aspect of ancestor with PANTHER:PTN000311349" nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000311349 CG11710 "IPR009349:Zinc finger, C2HC5-type, IPR007374:ASCH domain, IPR015947:PUA-like domain" CG11710 27-Aug-18 DroID_v2018_08 Drer\trip4 Scer\YKR023W Cele\asc-1 Xtro\trip4 Mmus\Trip4 Hsap\TRIP4 "viable,fertile" FBgn0038279 Sdr Secreted decoy of InR http://flybase.org/reports/FBgn0038279 protein_coding_gene ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR006211 transmembrane receptor protein tyrosine kinase activity ; GO:0004714 | inferred from electronic annotation with InterPro:IPR006211 insulin-like growth factor binding ; GO:0005520 | inferred from physical interaction with Ilp3 transmembrane receptor protein tyrosine kinase signaling pathway ; GO:0007169 | inferred from electronic annotation with InterPro:IPR006211 protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR006211 negative regulation of multicellular organism growth ; GO:0040015 | inferred from mutant phenotype response to starvation ; GO:0042594 | inferred from mutant phenotype membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR006211 extracellular space ; GO:0005615 | inferred from direct assay "Sdr, CG3837" "IPR000494:Receptor L-domain, IPR006211:Furin-like cysteine-rich domain, IPR003961:Fibronectin type III, IPR032675:Leucine-rich repeat domain, L domain-like, IPR013783:Immunoglobulin-like fold" CG3837 27-Aug-18 DroID_v2018_08 "Drer\LOC100329589, Drer\ephb6, Drer\epha7, Drer\epha2b, Drer\epha6, Drer\epha5, Drer\ephb3, Drer\igf1rb, Drer\epha4l, Drer\epha8, Drer\epha2a, Drer\ek1, Drer\ephb4b, Drer\ephb2b, Drer\ephb4a, Drer\ephb2a, Drer\insra, Drer\epha4b, Drer\igf1ra, Drer\insrb, Drer\ephb3a, Drer\epha4a" - "Cele\vab-1, Cele\daf-2, Cele\ddr-2, Cele\rol-3, Cele\F09A5.2" "Xtro\igf1r, Xtro\insrr, Xtro\insr" "Mmus\Epha8, Mmus\Epha6, Mmus\Epha3, Mmus\Ephb1, Mmus\Epha7, Mmus\Igf1r, Mmus\Insr, Mmus\Epha10, Mmus\Epha1, Mmus\Epha5, Mmus\Ephb3, Mmus\Ros1, Mmus\Ephb2, Mmus\Ephb4, Mmus\Insrr, Mmus\Epha4, Mmus\Epha2" "Hsap\EPHB4, Hsap\EPHA4, Hsap\INSR, Hsap\INSRR, Hsap\EPHA10, Hsap\EPHA3, Hsap\EPHA5, Hsap\EPHB3, Hsap\EPHB2, Hsap\EPHA6, Hsap\EPHA7, Hsap\EPHA1, Hsap\IGF1R, Hsap\ROS1, Hsap\EPHA2, Hsap\EPHB1, Hsap\EPHA8" "large body,size defective,decreased cell size,viable,increased cell size,increased cell number,visible" "trichogen cell,mesothoracic tergum" FBgn0050267 asRNA:CR30267 - http://flybase.org/reports/FBgn0050267 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT28638, CG30267, CR30267" - CR30267 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0033867 Cpr50Ca Cuticular protein 50Ca http://flybase.org/reports/FBgn0033867 protein_coding_gene structural constituent of cuticle ; GO:0042302 | inferred from electronic annotation with InterPro:IPR000618 structural constituent of chitin-based larval cuticle ; GO:0008010 | inferred from sequence model chitin-based cuticle development ; GO:0040003 | inferred from sequence model extracellular matrix ; GO:0031012 | inferred from sequence model "Cpr50Ca, CG13338" "IPR000618:Insect cuticle protein, IPR031311:Chitin-binding type R&R consensus" CG13338 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0263562 mir-4948 mir-4948 stem loop http://flybase.org/reports/FBgn0263562 miRNA_gene - - - "mir-4948, dme-mir-4948, CR43547" - CR43547 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0011099 l(1)Q59 lethal (1) Q59 http://flybase.org/reports/FBgn0011099 FBgn0010210 gene - - - l(1)Q59 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0003305 raised-wing raised wing http://flybase.org/reports/FBgn0003305 - gene - - - "rw, raised-wing" - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,reduced" wing FBgn0022321 l(1)B6.1 lethal (1) B6.1 http://flybase.org/reports/FBgn0022321 - gene - - - "B6.1, l(1)B6.1" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0032793 CG10189 - http://flybase.org/reports/FBgn0032793 protein_coding_gene tRNA binding ; GO:0000049 | inferred from electronic annotation with InterPro:IPR019407 sulfurtransferase activity ; GO:0016783 | inferred from biological aspect of ancestor with PANTHER:PTN000466898 tRNA thio-modification ; GO:0034227 | inferred from sequence or structural similarity with UniProtKB:P53923 tRNA wobble uridine modification ; GO:0002098 | inferred from sequence or structural similarity with UniProtKB:P53923 tRNA wobble position uridine thiolation ; GO:0002143 | inferred from biological aspect of ancestor with PANTHER:PTN000466898 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000466898 cytosol ; GO:0005829 | inferred from sequence or structural similarity with UniProtKB:P53923 "i180, i199, CG10189" "IPR019407:Cytoplasmic tRNA 2-thiolation protein 2, IPR014729:Rossmann-like alpha/beta/alpha sandwich fold" CG10189 27-Aug-18 DroID_v2018_08 Drer\ctu2 "Scer\NCS6, Scer\NCS2" Cele\tut-2 Xtro\ctu2 "Mmus\Ctu2, Mmus\Ctu1" "Hsap\CTU1, Hsap\CTU2" "viable,fertile" FBgn0000001 4.5SRNA 4.5SRNA http://flybase.org/reports/FBgn0000001 - non_protein_coding_gene - - - 4.5SRNA - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0025683 CG3164 - http://flybase.org/reports/FBgn0025683 FBgn0031221 protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR017871 cholesterol transporter activity ; GO:0017127 | inferred from biological aspect of ancestor with PANTHER:PTN001059382 sterol-transporting ATPase activity ; GO:0034041 | inferred from biological aspect of ancestor with PANTHER:PTN001059382" - integral component of membrane ; GO:0016021 | inferred from biological aspect of ancestor with PANTHER:PTN000443108 plasma membrane ; GO:0005886 | inferred from biological aspect of ancestor with PANTHER:PTN000443108 "CK02656, BEST:CK02656, CG3164" "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR013525:ABC-2 type transporter, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR017871:ABC transporter, conserved site" CG3164 27-Aug-18 DroID_v2018_08 "Drer\abcg8, Drer\abcg4b, Drer\abcg4a, Drer\abcg2c, Drer\abcg5, Drer\abcg1, Drer\abcg2b, Drer\abcg2a" "Scer\YOL075C, Scer\SNQ2, Scer\PDR10, Scer\PDR15, Scer\ADP1, Scer\PDR18" "Cele\wht-3, Cele\wht-7, Cele\wht-8, Cele\wht-4, Cele\wht-6, Cele\wht-1, Cele\abch-1" "Xtro\abcg5, Xtro\abcg8" "Mmus\Abcg3, Mmus\Abcg1, Mmus\Abcg2, Mmus\Abcg5, Mmus\Abcg8, Mmus\Abcg4" "Hsap\ABCG4, Hsap\ABCG5, Hsap\ABCG8, Hsap\ABCG2, Hsap\ABCG1" "viable,partially lethal - majority die" FBgn0039199 CG13615 - http://flybase.org/reports/FBgn0039199 protein_coding_gene - - - CG13615 IPR006631:Protein of unknown function DM4/12 CG13615 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC24018 K -0.438474938 -0.297190115 -0.408138967 -0.275194658 2.451486296 -0.102750772 FBgn0002878 mus101 mutagen-sensitive 101 http://flybase.org/reports/FBgn0002878 FBgn0030515 protein_coding_gene - mitotic DNA replication checkpoint ; GO:0033314 | inferred from mutant phenotype mitotic nuclear division ; GO:0007067 | traceable author statement oogenesis ; GO:0048477 | traceable author statement mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from mutant phenotype inferred from genetic interaction with nbs DNA replication initiation ; GO:0006270 | inferred from biological aspect of ancestor with PANTHER:PTN000339409 - "DmMus101, anon-WO0148202.1, fs(1)K451, mus 101, mus(1)101, mus-101, CG11156, mus101, Mus101, TOPBP1" IPR001357:BRCT domain CG11156 27-Aug-18 DroID_v2018_08 "Drer\ect2, Drer\topbp1" Scer\DPB11 "Cele\ect-2, Cele\mus-101" "Xtro\ect2, Xtro\topbp1, Xtro\slf1" "Mmus\Ect2, Mmus\Slf1, Mmus\Topbp1" "Hsap\SLF1, Hsap\ECT2, Hsap\TOPBP1" embryonic stage | 0-4 hr "chemical sensitive,radiation sensitive,DNA repair defective,wild-type,lethal,recessive,female sterile,partially,heat sensitive,lethal - all die before end of larval stage,some die during larval stage,female sterile germline-dependent,viable" "imaginal disc,mitosis & nuclear chromosome,heterochromatin,chromatin" FBgn0001054 Fs(3)Kar Female sterile (3) Kartal http://flybase.org/reports/FBgn0001054 - gene molecular_function ; GO:0003674 | no biological data available embryonic cleavage ; GO:0040016 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "Kar, Fs(3)Kartal, Fs(3)Sz27, Fs(3)Kar" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "cleavage stage embryo,maternal effect" FBgn0016737 SR3-7 SR3-7 http://flybase.org/reports/FBgn0016737 - gene - - - SR3-7 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0265160 lncRNA:CR44229 - http://flybase.org/reports/FBgn0265160 non_protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG44229, CR44229" - CR44229 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060970 l(3)SzB90Co lethal (3) SzB90Co http://flybase.org/reports/FBgn0060970 gene - - - "0297/01, l(3)S029701b, l(3)SzB90Co" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0263829 CG34334 - http://flybase.org/reports/FBgn0263829 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 mRNA binding ; GO:0003729 | inferred from sequence or structural similarity - - "CG34334, cg9561, CG9561" "IPR000504:RNA recognition motif domain, IPR034201:RNPS1, RNA recognition motif" CG34334 27-Aug-18 DroID_v2018_08 "Drer\srsf2b, Drer\pabpn1l, Drer\pabpn1, Drer\rnps1, Drer\srsf2a, Drer\LOC103909923" Scer\SGN1 "Cele\rnp-5, Cele\rsp-4" "Xtro\srsf2, Xtro\pabpn1, Xtro\rnps1, Xtro\pabpn1l" "Mmus\Pnn, Mmus\Pabpn1l, Mmus\Rnps1, Mmus\Srsf2, Mmus\Pabpn1, Mmus\Bcl2l2" "Hsap\RNPS1, Hsap\SRSF2, Hsap\BCL2L2, Hsap\BCL2L2-PABPN1, Hsap\PABPN1, Hsap\PABPN1L" FBgn0027630 ms(1)66 ms(1)66 http://flybase.org/reports/FBgn0027630 - gene - - - ms(1)66 - - 27-Aug-18 DroID_v2018_08 - - - - - - male sterile meiosis I FBgn0032803 CG13082 - http://flybase.org/reports/FBgn0032803 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG13082 - CG13082 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile,visible" trichogen cell FBgn0065900 l(2)SH0201 lethal (2) SH0201 http://flybase.org/reports/FBgn0065900 gene - - - l(2)SH0201 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0002390 l(3)93Dg lethal (3) 93Dg http://flybase.org/reports/FBgn0002390 - gene - - - "er13, l(3)er13, l(3)93Dg" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0067778 els ellsworth http://flybase.org/reports/FBgn0067778 gene molecular_function ; GO:0003674 | no biological data available bicoid mRNA localization ; GO:0045450 | inferred from mutant phenotype pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available els - - 27-Aug-18 DroID_v2018_08 - - - - - - female sterile "nurse cell,germline clone,oocyte,egg,embryonic head" FBgn0051017 PH4alphaNE3 prolyl-4-hydroxylase-alpha NE3 http://flybase.org/reports/FBgn0051017 protein_coding_gene "procollagen-proline 4-dioxygenase activity ; GO:0004656 | inferred from electronic annotation with InterPro:IPR013547 L-ascorbic acid binding ; GO:0031418 | inferred from electronic annotation with InterPro:IPR006620 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen ; GO:0016702 | inferred from electronic annotation with InterPro:IPR013547 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR006620" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005123, InterPro:IPR006620, InterPro:IPR013547" endoplasmic reticulum ; GO:0005783 | inferred from electronic annotation with InterPro:IPR013547 "CG9708, CG31017, PH4alphaNE3" "IPR005123:Oxoglutarate/iron-dependent dioxygenase, IPR006620:Prolyl 4-hydroxylase, alpha subunit, IPR013547:Prolyl 4-hydroxylase alpha-subunit, N-terminal" CG31017 27-Aug-18 DroID_v2018_08 "Drer\zgc:158254, Drer\p4htm, Drer\p4ha2, Drer\p4ha1a, Drer\zgc:152670, Drer\p4ha1b, Drer\p4ha3" - "Cele\phy-4, Cele\Y43F8B.19, Cele\phy-2, Cele\phy-3, Cele\C14E2.4" "Xtro\p4ha2, Xtro\p4ha1, Xtro\p4ha3" "Mmus\P4ha3, Mmus\P4htm, Mmus\P4ha2, Mmus\P4ha1" "Hsap\P4HA2, Hsap\P4HA3, Hsap\P4HA1, Hsap\P4HTM" viable FBgn0001542 l(1)14Ea lethal (1) 14Ea http://flybase.org/reports/FBgn0001542 - gene - - - "l(1)k22a, k22a, l(1)14Ea" - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0030088 Arfrp1 ADP-ribosylation factor related protein 1 http://flybase.org/reports/FBgn0030088 protein_coding_gene "GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR005225, InterPro:IPR006689, InterPro:IPR024156" small GTPase mediated signal transduction ; GO:0007264 | inferred from electronic annotation with InterPro:IPR024156 biological_process ; GO:0008150 | no biological data available intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR024156 cellular_component ; GO:0005575 | no biological data available "CG7039, Q9W389, Arp1, Arfrp1, ARFRP1, ARP" "IPR005225:Small GTP-binding protein domain, IPR006689:Small GTPase superfamily, ARF/SAR type, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR024156:Small GTPase superfamily, ARF type" CG7039 27-Aug-18 DroID_v2018_08 "Drer\arfrp1, Drer\arl13b" Scer\ARL3 Cele\Y54E10BR.2 "Xtro\eral1, Xtro\arfrp1" "Mmus\Arl13b, Mmus\Arfrp1" "Hsap\ARL13B, Hsap\ARFRP1" "lethal,viable,visible" "embryonic/larval brain,trichogen cell" DRSC18417 K -0.099003464 -0.10536053 -0.472733818 -1.35336419 0.352440365 1.628296447 FBgn0265745 lncRNA:CR44552 - http://flybase.org/reports/FBgn0265745 non_protein_coding_gene - - - CR44552 - CR44552 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0024862 l(3)09402 lethal (3) 09402 http://flybase.org/reports/FBgn0024862 - gene - - - "9402, l(3)09402" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0051308 CG31308 - http://flybase.org/reports/FBgn0051308 protein_coding_gene - - - CG31308 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0025839 ND-B14.5A NADH dehydrogenase (ubiquinone) B14.5 A subunit http://flybase.org/reports/FBgn0025839 "FBgn0014087, FBgn0047059" protein_coding_gene NADH dehydrogenase (ubiquinone) activity ; GO:0008137 | inferred from electronic annotation with InterPro:IPR009947 NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:O95182 "mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from biological aspect of ancestor with PANTHER:PTN000968153 mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with UniProtKB:O95182" mitochondrial respiratory chain complex I ; GO:0005747 | inferred from biological aspect of ancestor with PANTHER:PTN000968153 mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:O95182 "anon-2Db, 152A3.7, EG:152A3.7, RNAA, anon-2D, BcDNA:RE75088, CG3621, N4AM, ND-B14.5A" IPR009947:NADH:ubiquinone oxidoreductase subunit B14.5a CG3621 27-Aug-18 DroID_v2018_08 Drer\ndufa7 - Cele\F45H10.3 - Mmus\Ndufa7 Hsap\NDUFA7 FBgn0035077 CG9083 - http://flybase.org/reports/FBgn0035077 protein_coding_gene - - - CG9083 - CG9083 27-Aug-18 DroID_v2018_08 - Scer\RNQ1 - - - - FBgn0040247 anon-57Ba anon-57Ba http://flybase.org/reports/FBgn0040247 gene - - - anon-57Ba - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0263443 asRNA:CR43466 - http://flybase.org/reports/FBgn0263443 non_protein_coding_gene - - - CR43466 - CR43466 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267046 CG45490 - http://flybase.org/reports/FBgn0267046 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG45490 - CG45490 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001527 l(1)11Ec lethal (1) 11Ec http://flybase.org/reports/FBgn0001527 - gene - - - l(1)11Ec - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" FBgn0050274 CG30274 - http://flybase.org/reports/FBgn0050274 protein_coding_gene "kinase activity ; GO:0016301 | inferred from electronic annotation with InterPro:IPR022413, InterPro:IPR022414" - - "CG13529, CG30274" "IPR000749:ATP:guanido phosphotransferase, IPR014746:Glutamine synthetase/guanido kinase, catalytic domain, IPR022413:ATP:guanido phosphotransferase, N-terminal, IPR022414:ATP:guanido phosphotransferase, catalytic domain" CG30274 27-Aug-18 DroID_v2018_08 "Drer\ckbb, Drer\ckmt2b, Drer\ckma, Drer\ckmb, Drer\ckba, Drer\zgc:172076, Drer\ckmt1, Drer\ckmt2a" - "Cele\ZC434.8, Cele\F32B5.1, Cele\F11G11.13, Cele\F46H5.3, Cele\argk-1, Cele\W10C8.5" "Xtro\ckb, Xtro\ckm, Xtro\ckmt1b" "Mmus\Ckmt2, Mmus\Ckmt1, Mmus\Ckm, Mmus\Ckb" "Hsap\CKM, Hsap\CKMT1A, Hsap\CKMT1B, Hsap\CKMT2, Hsap\CKB" viable FBgn0010123 l(1)EN7 lethal (1) from Eugene Nonautonomous 7 http://flybase.org/reports/FBgn0010123 - gene - - - l(1)EN7 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,recessive,some die during pupal stage" fat body FBgn0015913 big bendless interacting gene product http://flybase.org/reports/FBgn0015913 - gene - - - big - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0028844 CG15283 - http://flybase.org/reports/FBgn0028844 protein_coding_gene - regulation of establishment of planar polarity ; GO:0090175 | inferred from mutant phenotype - "DS08340.1, BG:DS08340.1, CG15283" IPR012875:Protein of unknown function DUF1674 CG15283 27-Aug-18 DroID_v2018_08 Drer\sdhaf4 Scer\SDH8 Cele\W02D3.12 Xtro\sdhaf4 Mmus\Sdhaf4 Hsap\SDHAF4 "viable,planar polarity defective" "wing hair,ommatidium" FBgn0039101 CG16710 - http://flybase.org/reports/FBgn0039101 protein_coding_gene "serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" - "CG16710, SP16" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG16710 27-Aug-18 DroID_v2018_08 "Drer\f9a, Drer\masp2, Drer\f10" - "Cele\svh-1, Cele\try-1" Xtro\f2 "Mmus\Klk1b9, Mmus\F10, Mmus\Klk1b5, Mmus\F9" "Hsap\F2, Hsap\MASP1" "viable,visible" trichogen cell FBgn0066304 Rpp20 Rpp20 http://flybase.org/reports/FBgn0066304 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR002775 protein binding ; GO:0005515 | inferred from physical interaction with SA-2 ribonuclease P activity ; GO:0004526 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001433784 "RNA phosphodiester bond hydrolysis, endonucleolytic ; GO:0090502 | inferred from biological aspect of ancestor with PANTHER:PTN001433784 tRNA processing ; GO:0008033 | inferred from biological aspect of ancestor with PANTHER:PTN001433784" cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay mitochondrial ribonuclease P complex ; GO:0030678 | non-traceable author statement ribonuclease P complex ; GO:0030677 | non-traceable author statement "dRpp20, CG12533, CG32530, CG33931, BcDNA:RE70209, CG32530-ORFA, Rpp20" "IPR002775:DNA/RNA-binding protein Alba-like, IPR014612:Ribonucleases P/MRP protein subunit Rpp20" CG33931 27-Aug-18 DroID_v2018_08 Drer\pop7 - Cele\Y62E10A.2 - Mmus\Pop7 Hsap\POP7 DRSC19467 I -0.252305484 1.617374953 0.031056917 -0.890437835 -0.378523315 -0.463887417 FBgn0031834 CG13766 - http://flybase.org/reports/FBgn0031834 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from sequence model SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ; GO:0031146 | inferred from sequence model SCF ubiquitin ligase complex ; GO:0019005 | inferred from sequence model "CG13766, FBXO16" "IPR032675:Leucine-rich repeat domain, L domain-like" CG13766 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0265905 lncRNA:CR44694 - http://flybase.org/reports/FBgn0265905 non_protein_coding_gene - - - CR44694 - CR44694 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0264324 spg sponge http://flybase.org/reports/FBgn0264324 protein_coding_gene Rho guanyl-nucleotide exchange factor activity ; GO:0005089 | inferred from sequence or structural similarity with mbc small GTPase mediated signal transduction ; GO:0007264 | inferred from electronic annotation with InterPro:IPR026791 central nervous system development ; GO:0007417 | inferred from mutant phenotype R7 cell differentiation ; GO:0045466 | inferred from mutant phenotype activation of GTPase activity ; GO:0090630 | inferred from sequence or structural similarity with mbc cytoplasm ; GO:0005737 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "CG31048, spg, mat(3)6, mat3(6), CG14530, CG11754, Dm Dock4, Spg" "IPR027357:DHR-2 domain, IPR027007:DHR-1 domain, IPR026791:Dedicator of cytokinesis, IPR031057:DOCK1 homologue, IPR011989:Armadillo-like helical, IPR001452:SH3 domain, IPR010703:Dedicator of cytokinesis, C-terminal, IPR032376:Dedicator of cytokinesis, N-terminal domain" CG31048 27-Aug-18 DroID_v2018_08 "Drer\dock5, Drer\dock4b, Drer\dock1, Drer\dock3, Drer\si:dkey-81e3.1" Scer\DCK1 Cele\ced-5 "Xtro\dock2, Xtro\dock4, Xtro\dock1, Xtro\dock3" "Mmus\Dock4, Mmus\Dock5, Mmus\Dock3, Mmus\Dock1, Mmus\Dock2" "Hsap\DOCK2, Hsap\DOCK3, Hsap\DOCK1, Hsap\DOCK4, Hsap\DOCK5" DRSC14373 K 0.514689583 -0.029580176 -0.674992531 -0.268635216 1.278231026 1.870291905 FBgn0034931 CG2812 - http://flybase.org/reports/FBgn0034931 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG2812 "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain" CG2812 27-Aug-18 DroID_v2018_08 "Drer\wdr47a, Drer\wdr47b" Scer\STE4 Cele\nmtn-1 Xtro\wdr47 Mmus\Wdr47 Hsap\WDR47 DRSC04319 E 0.110972793 -0.660044717 1.312456419 -2.172168795 -0.325159383 0.517171597 FBgn0053493 CG33493 - http://flybase.org/reports/FBgn0053493 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG6463, CG33493" - CG33493 27-Aug-18 DroID_v2018_08 Drer\ndufa5 - - Xtro\ndufa5 Mmus\Ndufa5 Hsap\NDUFA5 DRSC10642 K 0.787123651 0.548234082 -0.009949425 0.956559679 0.383486706 1.65407862 FBgn0039067 wda will decrease acetylation http://flybase.org/reports/FBgn0039067 protein_coding_gene histone acetyltransferase activity ; GO:0004402 | contributes_to inferred from direct assay histone H3 acetylation ; GO:0043966 | inferred from direct assay positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype histone H3-K9 acetylation ; GO:0043970 | inferred from mutant phenotype SAGA complex ; GO:0000124 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "Wda, wda, CG4448, WFA, WDA" "IPR001680:WD40 repeat, IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR019775:WD40 repeat, conserved site, IPR020472:G-protein beta WD-40 repeat, IPR007582:TFIID subunit TAF5, NTD2 domain" CG4448 27-Aug-18 DroID_v2018_08 "Drer\egln1a, Drer\taf5, Drer\taf5l, Drer\egln1b, Drer\egln3, Drer\egln2" Scer\TAF5 Cele\taf-5 "Xtro\egln3, Xtro\egln2, Xtro\egln1, Xtro\taf5, Xtro\taf5l" "Mmus\Egln1, Mmus\Taf5, Mmus\Egln2, Mmus\Taf5l, Mmus\Wdr38, Mmus\Egln3" "Hsap\EGLN1, Hsap\EGLN2, Hsap\EGLN3, Hsap\TAF5L, Hsap\TAF5" "lethal - all die before end of second instar larval stage,some die during second instar larval stage,viable,visible" trichogen cell DRSC15579 IE 1.694845856 0.932294183 0.097777079 1.661479182 0.21828886 0.372780212 FBgn0050326 tRNA:Val-AAC-2-2 transfer RNA:Valine-AAC 2-2 http://flybase.org/reports/FBgn0050326 tRNA_gene GUU codon-amino acid adaptor activity ; GO:0033449 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033449 cytosol ; GO:0005829 | inferred by curator from GO:0033449 "CR30326, AE002787.trna52-ValAAC, valine tRNA, tRNA[Val][[4]], tRNA:val4:56D, tRNA:V4:56D, tRNA:V:AAC:AE002787-b, CR30226, tRNA[Val-AAC], chr2R.trna35-ValAAC, tRNA:Val-AAC-2-2, tRNA:CR30326, tRNA-Val-AAC-2-2, GUU" - CR30326 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0058096 CG40096 - http://flybase.org/reports/FBgn0058096 protein_coding_gene - - - CG40096 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0027622 297\pol 297 element pol http://flybase.org/reports/FBgn0027622 - transposable_element_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR012337 aspartic-type endopeptidase activity ; GO:0004190 | inferred from electronic annotation with InterPro:IPR001969 proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001969 DNA integration ; GO:0015074 | inferred from electronic annotation with InterPro:IPR001584 - "297\pol, pol" "IPR021109:Aspartic peptidase domain, IPR000477:Reverse transcriptase domain, IPR001584:Integrase, catalytic core, IPR001969:Aspartic peptidase, active site, IPR012337:Ribonuclease H-like domain" - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035213 CG2199 - http://flybase.org/reports/FBgn0035213 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - "CG2199, FBpp0072605" "IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG2199 27-Aug-18 DroID_v2018_08 "Drer\im:7147486, Drer\znf142" Scer\RME1 - - "Mmus\Zfp142, Mmus\Zfp574" "Hsap\ZNF574, Hsap\ZNF142, Hsap\TP63" "viable,visible" trichogen cell FBgn0013526 l(2)23AB4 lethal (2) 23AB4 http://flybase.org/reports/FBgn0013526 - gene - - - "l(2)23Af, l(2)23AB4" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0259463 C442 - http://flybase.org/reports/FBgn0259463 gene - - - C442 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing vein,wing,chaeta" FBgn0040370 CG13375 - http://flybase.org/reports/FBgn0040370 protein_coding_gene "GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR001806 GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR005225, InterPro:IPR020849" signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR020849 biological_process ; GO:0008150 | no biological data available membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR020849 cellular_component ; GO:0005575 | no biological data available "EG:BACR37P7.8, CG13375" "IPR001806:Small GTPase superfamily, IPR005225:Small GTP-binding protein domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR020849:Small GTPase superfamily, Ras type" CG13375 27-Aug-18 DroID_v2018_08 "Drer\diras1b, Drer\kras, Drer\diras2, Drer\si:dkey-27j5.5, Drer\gem, Drer\zgc:171704, Drer\diras1a, Drer\ralab, Drer\hrasb, Drer\rasl12, Drer\rrad, Drer\rergla, Drer\rasl11b, Drer\rsg1, Drer\zgc:153845, Drer\hrasa, Drer\zgc:110699, Drer\LOC100332969, Drer\rit1, Drer\zgc:152698, Drer\ralba, Drer\mras, Drer\si:dkeyp-59c12.1, Drer\rerglb, Drer\ralbb, Drer\rhebl1, Drer\rap1ab, Drer\rap1aa, Drer\rap2c, Drer\ralaa, Drer\rem2, Drer\rasd1, Drer\rras2, Drer\zgc:64022, Drer\rap2ab, Drer\rasl10a, Drer\rheb, Drer\si:ch73-116o1.2, Drer\rap2b, Drer\rem1, Drer\rasl11a, Drer\rras, Drer\nras, Drer\zgc:114118" "Scer\RAS1, Scer\RAS2, Scer\RSR1, Scer\RHB1" "Cele\ssr-2, Cele\D1081.4" "Xtro\gem, Xtro\diras2, Xtro\kras, Xtro\rem2, Xtro\rap2b, Xtro\rasd1, Xtro\LOC733456, Xtro\rem1, Xtro\rasl10a, Xtro\rap2a, Xtro\rap2c, Xtro\rit1, Xtro\rhebl1, Xtro\nras, Xtro\ras-dva, Xtro\rerg, Xtro\diras1, Xtro\rala, Xtro\rergl, Xtro\rasd2, Xtro\rheb, Xtro\hras, Xtro\rsg1, Xtro\rrad, Xtro\ralb, Xtro\rap1b, Xtro\rap1a, Xtro\diras3, Xtro\rasl11b" "Mmus\Rap1a, Mmus\Diras2, Mmus\Rap1b, Mmus\Gem, Mmus\Rasl10a, Mmus\Rheb, Mmus\Rrad, Mmus\Rasl12, Mmus\Gm266, Mmus\Eras, Mmus\Rasd2, Mmus\Mras, Mmus\Rergl, Mmus\Rasd1, Mmus\Rem2, Mmus\Rerg, Mmus\Rhebl1, Mmus\Rras, Mmus\Rasl11b, Mmus\Rap2c, Mmus\Rit2, Mmus\Rsg1, Mmus\Ralb, Mmus\Rem1, Mmus\Hras, Mmus\Diras1, Mmus\Nras, Mmus\Rasl11a, Mmus\Rasl10b, Mmus\Rit1, Mmus\Rap2a, Mmus\Rap2b, Mmus\Rras2, Mmus\Rala, Mmus\Kras" "Hsap\RHEBL1, Hsap\KRAS, Hsap\DIRAS1, Hsap\RERGL, Hsap\MRAS, Hsap\RRAS, Hsap\DIRAS2, Hsap\DIRAS3, Hsap\RRAD, Hsap\RAP2B, Hsap\RASL10B, Hsap\RASD2, Hsap\RASL12, Hsap\RAP2A, Hsap\RAP1A, Hsap\RASL11A, Hsap\RIT2, Hsap\RASL11B, Hsap\RHEB, Hsap\REM2, Hsap\HRAS, Hsap\RERG, Hsap\GEM, Hsap\NRAS, Hsap\RALB, Hsap\RALA, Hsap\RRAS2, Hsap\REM1, Hsap\RIT1, Hsap\RASD1, Hsap\RASL10A, Hsap\RAP1B, Hsap\RAP2C, Hsap\RSG1, Hsap\ERAS" viable FBgn0004513 Mdr65 Multi drug resistance 65 http://flybase.org/reports/FBgn0004513 - protein_coding_gene "ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003439, InterPro:IPR011527, InterPro:IPR017871 efflux transmembrane transporter activity ; GO:0015562 | inferred from direct assay xenobiotic-transporting ATPase activity ; GO:0008559 | inferred from direct assay" transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011527 establishment of glial blood-brain barrier ; GO:0060857 | inferred from direct assay renal tubular secretion ; GO:0097254 | inferred from expression pattern response to toxic substance ; GO:0009636 | inferred from expression pattern xenobiotic transport ; GO:0042908 | inferred from direct assay ATP-binding cassette (ABC) transporter complex ; GO:0043190 | inferred from direct assay pleated septate junction ; GO:0005919 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay "Mdr65A, CG10181, Mdr65, mdr65, MDR65, P-gp, P-glycoprotein" "IPR003439:ABC transporter-like, IPR003593:AAA+ ATPase domain, IPR011527:ABC transporter type 1, transmembrane domain, IPR017871:ABC transporter, conserved site, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG10181 27-Aug-18 DroID_v2018_08 "Drer\abcb4, Drer\abcb8, Drer\abcb3l1, Drer\abcb11a, Drer\abcb11b, Drer\abcb10, Drer\abcb9, Drer\abcb5" Scer\STE6 "Cele\pgp-5, Cele\haf-4, Cele\haf-8, Cele\haf-1, Cele\pgp-7, Cele\pgp-9, Cele\haf-6, Cele\pgp-1, Cele\pgp-4, Cele\haf-2, Cele\pgp-10, Cele\haf-3, Cele\pgp-8, Cele\pgp-6, Cele\pgp-14, Cele\pgp-12, Cele\pgp-3, Cele\pgp-2, Cele\haf-7, Cele\pgp-13, Cele\pgp-11, Cele\haf-9" "Xtro\abcb8, Xtro\LOC100494740" "Mmus\Abcb9, Mmus\Abcb11, Mmus\Abcb1a, Mmus\Abcb10, Mmus\Abcb4, Mmus\Abcb5, Mmus\Abcb8, Mmus\Abcb1b" "Hsap\ABCB11, Hsap\ABCB4, Hsap\ABCB8, Hsap\ABCB5, Hsap\ABCB1, Hsap\ABCB10" viable FBgn0036531 CG6244 - http://flybase.org/reports/FBgn0036531 protein_coding_gene RNA polymerase II core binding ; GO:0000993 | inferred from biological aspect of ancestor with PANTHER:PTN000468320 transcription elongation from RNA polymerase II promoter ; GO:0006368 | inferred from biological aspect of ancestor with PANTHER:PTN000468320 chromatin-mediated maintenance of transcription ; GO:0048096 | inferred from biological aspect of ancestor with PANTHER:PTN000468320 transcription elongation factor complex ; GO:0008023 | inferred from biological aspect of ancestor with PANTHER:PTN000468320 CG6244 IPR007808:Transcription elongation factor 1 CG6244 27-Aug-18 DroID_v2018_08 Drer\elof1 Scer\ELF1 Cele\Y54G11A.11 Xtro\elof1 "Mmus\Elof1, Mmus\Gm36718" Hsap\ELOF1 FBgn0030907 CG15058 - http://flybase.org/reports/FBgn0030907 protein_coding_gene - - - CG15058 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0029100 anon-89Bc anon-89Bc http://flybase.org/reports/FBgn0029100 gene - - - anon-89Bc - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065734 l(2)SH0545 lethal (2) SH0545 http://flybase.org/reports/FBgn0065734 gene - - - "l(2)SH0545, l(2)SH2 0545" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0014880 Sry-beta::Sry-delta Sry-beta::Sry-delta http://flybase.org/reports/FBgn0014880 - engineered_fusion_gene - - - Sry-beta::Sry-delta - - 27-Aug-18 DroID_v2018_08 - - - - - - female sterile FBgn0058139 CG40139 - http://flybase.org/reports/FBgn0058139 protein_coding_gene - - - CG40139 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032554 CG15278 - http://flybase.org/reports/FBgn0032554 protein_coding_gene - - - "bs32h08.y1, NEST:bs32h08, CG15278" - CG15278 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0037252 CG14650 - http://flybase.org/reports/FBgn0037252 protein_coding_gene - - - CG14650 "IPR001623:DnaJ domain, IPR032843:Cleavage inducing molecular chaperone, Jiv" CG14650 27-Aug-18 DroID_v2018_08 Drer\dnajc14 Scer\HLJ1 Cele\dnj-5 Xtro\dnajc14 Mmus\Dnajc14 Hsap\DNAJC14 viable FBgn0263084 HP1Lcsd Heterochromatin Protein 1L chromoshadow domain http://flybase.org/reports/FBgn0263084 protein_coding_gene chromatin binding ; GO:0003682 | inferred from sequence or structural similarity with Su(var)205 chromosome organization ; GO:0051276 | inferred from sequence or structural similarity with Su(var)205 nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR008251 chromatin ; GO:0000785 | inferred from sequence or structural similarity with Su(var)205 "HP1Lcsd, lincRNA.384, CG43352" "IPR016197:Chromo domain-like, IPR008251:Chromo shadow domain" CG43352 27-Aug-18 DroID_v2018_08 "Drer\cbx5, Drer\cbx1b, Drer\cbx1a" - - - "Mmus\Cbx5, Mmus\Cbx1" "Hsap\CBX1, Hsap\CBX5" FBgn0260320 GSd404 - http://flybase.org/reports/FBgn0260320 gene - - - GSd404 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,neuroanatomy defective" "intersegmental nerve,segmental nerve" FBgn0031644 CG15625 - http://flybase.org/reports/FBgn0031644 protein_coding_gene - - - CG15625 "IPR001660:Sterile alpha motif domain, IPR013761:Sterile alpha motif/pointed domain" CG15625 27-Aug-18 DroID_v2018_08 - - - - Mmus\Samd15 Hsap\SAMD15 "viable,fertile" FBgn0264912 lncRNA:CR44103 - http://flybase.org/reports/FBgn0264912 non_protein_coding_gene - - - "CR44103, lincRNA.679" - CR44103 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0027262 l(1)G0228 lethal (1) G0228 http://flybase.org/reports/FBgn0027262 - gene - - - l(1)G0228 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" adult abdomen FBgn0020857 fs(2)261404 female sterile(2)261404 http://flybase.org/reports/FBgn0020857 - gene - - - "fs(2)A, fs(2)261404" - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive" FBgn0260800 l(2)GSG317 - http://flybase.org/reports/FBgn0260800 gene - - - l(2)GSG317 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0034671 CG13494 - http://flybase.org/reports/FBgn0034671 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:AT17606, CG13494" - CG13494 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible" trichogen cell FBgn0040322 GNBP2 Gram-negative bacteria binding protein 2 http://flybase.org/reports/FBgn0040322 protein_coding_gene (1->3)-beta-D-glucan binding ; GO:0001872 | inferred from direct assay lipopolysaccharide binding ; GO:0001530 | inferred from direct assay signaling pattern recognition receptor activity ; GO:0008329 | inferred from sequence or structural similarity with GNBP1 beta-glucanase activity ; GO:0052736 | NOT inferred from key residues carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR000757 regulation of innate immune response ; GO:0045088 | inferred from sequence or structural similarity with UniProtKB:Q9NHB0 innate immune response-activating signal transduction ; GO:0002758 | inferred from sequence or structural similarity with GNBP1 extracellular region ; GO:0005576 | inferred from sequence or structural similarity with UniProtKB:Q9NHB0 proteasome complex ; GO:0000502 | colocalizes_with inferred from direct assay "GNBP, DGNBP-2, CG4144, GNBP2, gnbp2" "IPR000757:Glycoside hydrolase family 16, IPR013320:Concanavalin A-like lectin/glucanase domain, IPR031756:Beta-1,3-glucan-binding protein, N-terminal" CG4144 27-Aug-18 DroID_v2018_08 - "Scer\CRR1, Scer\UTR2, Scer\CRH1" Cele\Y53H1B.4 - - - viable FBgn0063904 Neurodegeneration-7 Neurodegeneration 7 http://flybase.org/reports/FBgn0063904 gene - - - "ND8, ND7, Neurodegeneration-7" - - 27-Aug-18 DroID_v2018_08 - - - - - - "paralytic,dominant" "central nervous system,brain" FBgn0053245 Ste:CG33245 Ste:CG33245 http://flybase.org/reports/FBgn0053245 protein_coding_gene protein kinase regulator activity ; GO:0019887 | inferred from mutant phenotype regulation of protein serine/threonine phosphatase activity ; GO:0080163 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay protein kinase CK2 complex ; GO:0005956 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG32605, CG33245, Ste:CG33245" "IPR016149:Casein kinase II, regulatory subunit, alpha-helical, IPR000704:Casein kinase II, regulatory subunit" CG33245 27-Aug-18 DroID_v2018_08 Drer\csnk2b "Scer\CKB2, Scer\CKB1" Cele\kin-10 Xtro\csnk2b Mmus\Csnk2b Hsap\CSNK2B FBgn0000840 fs(1)M27 female sterile (1) M27 http://flybase.org/reports/FBgn0000840 - gene - - - fs(1)M27 - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive,lethal,rescuable maternal effect,lethal - all die before end of embryonic stage,some die during embryonic stage" egg FBgn0260025 fonseca fonseca http://flybase.org/reports/FBgn0260025 gene - - - fonseca - - 27-Aug-18 DroID_v2018_08 - - - - - - chorion | germline clone FBgn0028889 tRNA:Leu-TAA-3-1 transfer RNA:Leucine-TAA 3-1 http://flybase.org/reports/FBgn0028889 tRNA_gene UUA codon-amino acid adaptor activity ; GO:0033403 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033403 cytosol ; GO:0005829 | inferred by curator from GO:0033403 "DtL[b], BG:DS03192.1, tRNA:leu, AE002690.trna13-LeuTAA, tRNA:L:TAA:AE002690, CR31831, tRNA[Leu], tRNA[LEU], chr2L.trna22-LeuTAA, tRNA-Leu-TAA-3-1, tRNA:Leu-TAA-3-1, tRNA:L:35C, UUA" - CR31831 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0000144 Attenuated Attenuated http://flybase.org/reports/FBgn0000144 - gene - - - "Attenuated, At" - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,male fertile,female fertile,visible,dominant,good,fertile" wing FBgn0040230 dbo diablo http://flybase.org/reports/FBgn0040230 protein_coding_gene ubiquitin-protein transferase activity ; GO:0004842 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN001973695 actin binding ; GO:0003779 | inferred from sequence or structural similarity protein homodimerization activity ; GO:0042803 | inferred from direct assay neuron projection morphogenesis ; GO:0048812 | inferred from mutant phenotype negative regulation of synaptic growth at neuromuscular junction ; GO:0045886 | inferred from mutant phenotype cell growth ; GO:0016049 | inferred from mutant phenotype regulation of synapse organization ; GO:0050807 | inferred from mutant phenotype Cul3-RING ubiquitin ligase complex ; GO:0031463 | inferred from biological aspect of ancestor with PANTHER:PTN001973695 "Dm.DBO, DIABLO, Smac, CG6224, dbo, Dbo, henji" "IPR000210:BTB/POZ domain, IPR006652:Kelch repeat type 1, IPR011705:BTB/Kelch-associated, IPR011333:SKP1/BTB/POZ domain, IPR017096:BTB-kelch protein, IPR011043:Galactose oxidase/kelch, beta-propeller, IPR015915:Kelch-type beta propeller" CG6224 27-Aug-18 DroID_v2018_08 "Drer\klhl17, Drer\klhl20, Drer\klhl2, Drer\klhl18, Drer\klhl12, Drer\klhl5, Drer\klhl3" - "Cele\R12E2.1, Cele\kel-1, Cele\kel-3" "Xtro\klhl17, Xtro\klhl20, Xtro\klhl4, Xtro\klhl12, Xtro\klhl5" "Mmus\Klhl5, Mmus\Klhl1, Mmus\Klhl12, Mmus\Klhl2, Mmus\Klhl17, Mmus\Klhl20, Mmus\Klhl3, Mmus\Klhl4, Mmus\Klhl18" "Hsap\KLHL17, Hsap\KLHL5, Hsap\KLHL4, Hsap\KLHL3, Hsap\KLHL1, Hsap\KLHL12, Hsap\KLHL18, Hsap\KLHL20, Hsap\KLHL2" "planar polarity defective,viable,fertile" wing hair FBgn0030100 CG12106 - http://flybase.org/reports/FBgn0030100 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BcDNA:GH03263, CG12106" IPR017920:COMM domain CG12106 27-Aug-18 DroID_v2018_08 Drer\commd3 - Cele\B0281.4 - Mmus\Commd3 Hsap\COMMD3 "viable,planar polarity defective" FBgn0015417 l(1)16ACa lethal (1) 16ACa http://flybase.org/reports/FBgn0015417 - gene - - - l(1)16ACa - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0014208 l(1)9-38-1 lethal (1) 9-38-1 http://flybase.org/reports/FBgn0014208 - gene - - - "l(1)14Cc, l(1)9-38-1" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0260363 GSd248 - http://flybase.org/reports/FBgn0260363 gene - - - GSd248 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,neuroanatomy defective" ventral nerve cord FBgn0020290 l(2)M167 lethal (2) M167 http://flybase.org/reports/FBgn0020290 - gene - - - l(2)M167 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,dominant,heat sensitive,recessive" FBgn0266808 lncRNA:CR45270 - http://flybase.org/reports/FBgn0266808 non_protein_coding_gene - - - CR45270 - CR45270 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0051333 tRNA:Thr-CGT-1-3 transfer RNA:Threonine-CGT 1-3 http://flybase.org/reports/FBgn0051333 tRNA_gene ACG codon-amino acid adaptor activity ; GO:0033440 | inferred from sequence model translation ; GO:0006412 | inferred by curator from GO:0033440 cytosol ; GO:0005829 | inferred by curator from GO:0033440 "AE002708.trna25-ThrCGT, tRNA[Thr][[4]], tRNA[Thr][[3]], tRNA:T3:93AB, tRNA:thr4:93A, tRNA:T4:93A, tRNA:T:CGT:AE002708-c, CR31333, tRNA[[Thr]], chr3R.trna31-ThrCGT, tRNA-Thr-CGT-1-3, tRNA:Thr-CGT-1-3, tRNA:CR31333, ACG" - CR31333 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0017610 Grt Glucose repressible transcripts http://flybase.org/reports/FBgn0017610 - gene - - - Grt - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0040646 CG14580 - http://flybase.org/reports/FBgn0040646 protein_coding_gene - - - CG14580 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0024237 fl338 fl338 http://flybase.org/reports/FBgn0024237 - gene molecular_function ; GO:0003674 | no biological data available - cellular_component ; GO:0005575 | no biological data available fl338 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,female,dosage compensation defective" FBgn0259187 Ir60d Ionotropic receptor 60d http://flybase.org/reports/FBgn0259187 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "CG13582, DmelIR60d, CG42291, Ir60d, IR60d" - CG42291 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005097 Fs(2)Y12 Female sterile (2) Y12 http://flybase.org/reports/FBgn0005097 - gene - - - "fs(2)Y12, Fs(2)Y12" - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,semidominant" egg FBgn0261880 Taf Tripped-and-fell http://flybase.org/reports/FBgn0261880 gene - - - Taf - - 27-Aug-18 DroID_v2018_08 - - - - - - "paralytic,dominant,heat sensitive,neurophysiology defective,viable" FBgn0265189 sud1 sudestada1 http://flybase.org/reports/FBgn0265189 protein_coding_gene "L-ascorbic acid binding ; GO:0031418 | inferred from electronic annotation with InterPro:IPR006620, InterPro:IPR019601 iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR006620, InterPro:IPR019601 L-ascorbic acid binding ; GO:0031418 | inferred from sequence model with InterPro:IPR006620,InterPro:IPR019601 peptidyl-proline dioxygenase activity ; GO:0031543 | inferred from direct assay" "oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005123, InterPro:IPR006620, InterPro:IPR019601 regulation of translation ; GO:0006417 | inferred from mutant phenotype oxidation-reduction process ; GO:0055114 | inferred from sequence model with InterPro:IPR005123,InterPro:IPR006620,InterPro:IPR019601 regulation of translational termination ; GO:0006449 | inferred from biological aspect of ancestor with PANTHER:PTN000251752 peptidyl-proline hydroxylation ; GO:0019511 | inferred from mutant phenotype protein hydroxylation ; GO:0018126 | inferred from direct assay" cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay "CG44254, CG18761, CG31120, sud1" "IPR019601:Oxoglutarate/iron-dependent oxygenase, C-terminal degradation domain, IPR006620:Prolyl 4-hydroxylase, alpha subunit, IPR005123:Oxoglutarate/iron-dependent dioxygenase" CG44254 27-Aug-18 DroID_v2018_08 Drer\ogfod1 "Scer\TPA1, Scer\GPI17" "Cele\hpo-5, Cele\C17G10.1" Xtro\ogfod1 "Mmus\Pigs, Mmus\Ogfod1" "Hsap\OGFOD1, Hsap\PIGS" "visible,body color defective,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" FBgn0065080 snoRNA:Me18S-A1374 - http://flybase.org/reports/FBgn0065080 snoRNA_gene - - - "Dm-122, snoR122, CR33634, snoRNA:Me18S-A1374, Me18S-A1374(snoR122), snoRNA:122" - CR33634 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0011074 l(1)Q27 lethal (1) Q27 http://flybase.org/reports/FBgn0011074 FBgn0010210 gene - - - l(1)Q27 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0065371 l(2)SH1701 lethal (2) SH1701 http://flybase.org/reports/FBgn0065371 gene - - - "l(2)SH1701, l(2)SH2 1701" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0031961 CG7102 - http://flybase.org/reports/FBgn0031961 protein_coding_gene ubiquitin protein ligase binding ; GO:0031625 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 protein ubiquitination involved in ubiquitin-dependent protein catabolic process ; GO:0042787 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 regulation of proteolysis ; GO:0030162 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 proteasome-mediated ubiquitin-dependent protein catabolic process ; GO:0043161 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 spliceosomal snRNP assembly ; GO:0000387 | inferred from sequence or structural similarity with HGNC:11161 catalytic step 2 spliceosome ; GO:0071013 | inferred from sequence or structural similarity with HGNC:11161 SCF ubiquitin ligase complex ; GO:0019005 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000698504 "CG17973, CG7102" "IPR000210:BTB/POZ domain, IPR006571:TLDc domain, IPR011705:BTB/Kelch-associated, IPR011333:SKP1/BTB/POZ domain" CG7102 27-Aug-18 DroID_v2018_08 - Scer\YIL001W - "Xtro\btbd9, Xtro\btbd19" Mmus\Btbd9 "Hsap\BTBD19, Hsap\BTBD9" viable DRSC03007 K -0.330952588 -0.370821336 -0.482054164 -0.382802781 -1.888000227 -0.290695145 FBgn0039028 CG13840 - http://flybase.org/reports/FBgn0039028 protein_coding_gene - - - CG13840 - CG13840 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0028398 Taf10 TBP-associated factor 10 http://flybase.org/reports/FBgn0028398 protein_coding_gene "transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly ; GO:0001075 | contributes_to inferred from direct assay" transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from direct assay transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC:11543 inferred from sequence or structural similarity with SGD:S000002574 transcription factor TFIID complex ; GO:0005669 | inferred from sequence or structural similarity with HGNC:11543 inferred from sequence or structural similarity with SGD:S000002574 histone acetyltransferase complex ; GO:0000123 | inferred from sequence or structural similarity with HGNC:11543 inferred from sequence or structural similarity with SGD:S000002574 nucleus ; GO:0005634 | inferred from direct assay transcription factor TFIID complex ; GO:0005669 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "dTAF[[II]]24, TAF[[II]]24, dmTAF10, dmTaf10, TAF, taf24, TFIID, TAF[[II]], TAF10, CG2859, dtafII24, dTAFII24, TafII24, Taf24, BcDNA:RE73934, Taf10, dTAF10" "IPR003923:Transcription initiation factor TFIID, 23-30kDa subunit" CG2859 27-Aug-18 DroID_v2018_08 Drer\taf10 Scer\TAF10 Cele\taf-10 Xtro\taf10 Mmus\Taf10 Hsap\TAF10 "planar polarity defective,partially lethal - majority die,some die during pupal stage" DRSC30091 K 0.664342779 1.806765162 FBgn0029819 Usp30 Ubiquitin specific protease 30 http://flybase.org/reports/FBgn0029819 protein_coding_gene thiol-dependent ubiquitin-specific protease activity ; GO:0004843 | inferred from sequence or structural similarity with MGI:MGI:2144157 ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from electronic annotation with InterPro:IPR018200 protein K11-linked deubiquitination ; GO:0035871 | inferred from sequence or structural similarity with UniProtKB:Q70CQ3 protein K6-linked deubiquitination ; GO:0044313 | inferred from sequence or structural similarity with UniProtKB:Q70CQ3 protein deubiquitination ; GO:0016579 | inferred from sequence or structural similarity with MGI:MGI:2144157 response to paraquat ; GO:1901562 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "CG3016, dUSP30, Usp30, USP30, Q9W462" "IPR001394:Peptidase C19, ubiquitin carboxyl-terminal hydrolase, IPR018200:Ubiquitin specific protease, conserved site, IPR028889:Ubiquitin specific protease domain" CG3016 27-Aug-18 DroID_v2018_08 "Drer\usp3, Drer\usp49, Drer\usp44, Drer\usp30, Drer\LOC100537262" "Scer\UBP16, Scer\UBP1, Scer\UBP8" Cele\Y67D2.2 "Xtro\usp30, Xtro\usp22, Xtro\usp3, Xtro\usp44, Xtro\usp49" "Mmus\Usp30, Mmus\Usp3, Mmus\Usp44, Mmus\Usp22, Mmus\Usp49, Mmus\Usp27x, Mmus\Usp51" "Hsap\USP30, Hsap\USP22, Hsap\USP51, Hsap\USP49, Hsap\USP44, Hsap\USP3" "locomotor behavior defective,short lived,viable" FBgn0005685 cob cobblestone http://flybase.org/reports/FBgn0005685 - gene - compound eye development ; GO:0048749 | inferred from mutant phenotype - cob - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive" "eye,ommatidium,eye photoreceptor cell" FBgn0014185 gyn-2 gyn-2 http://flybase.org/reports/FBgn0014185 - gene - - - gyn-2 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267555 asRNA:CR45895 - http://flybase.org/reports/FBgn0267555 non_protein_coding_gene - - - CR45895 - CR45895 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267006 lncRNA:CR45450 - http://flybase.org/reports/FBgn0267006 non_protein_coding_gene - - - CR45450 - CR45450 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260098 2L2218 - http://flybase.org/reports/FBgn0260098 gene - "terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype" - 2L2218 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" "terminal tracheal cell,somatic clone,embryonic/larval tracheal system" FBgn0005192 l(2)S55 lethal of Seto 55 http://flybase.org/reports/FBgn0005192 - gene - - - l(2)S55 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of pupal stage,some die during pupal stage" FBgn0060992 l(3)S027342b lethal (3) S027342b http://flybase.org/reports/FBgn0060992 gene - - - "0273/42, l(3)S027342b" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0014869 Pglym78 Phosphoglyceromutase http://flybase.org/reports/FBgn0014869 - protein_coding_gene "2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity ; GO:0046538 | inferred from biological aspect of ancestor with PANTHER:PTN000231842" regulation of glucose metabolic process ; GO:0010906 | inferred from mutant phenotype glycolytic process ; GO:0006096 | inferred from biological aspect of ancestor with PANTHER:PTN000231842 regulation of pentose-phosphate shunt ; GO:0043456 | inferred from biological aspect of ancestor with PANTHER:PTN000231842 myoblast fusion ; GO:0007520 | inferred from mutant phenotype somatic muscle development ; GO:0007525 | inferred from mutant phenotype gluconeogenesis ; GO:0006094 | inferred from biological aspect of ancestor with PANTHER:PTN000231842 Z disc ; GO:0030018 | inferred from direct assay cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000231842 M band ; GO:0031430 | inferred from direct assay "PGAM, Pglym, CG1721, Pglym78, PGLYM, pglym78" "IPR001345:Phosphoglycerate/bisphosphoglycerate mutase, active site, IPR005952:Phosphoglycerate mutase 1, IPR013078:Histidine phosphatase superfamily, clade-1, IPR029033:Histidine phosphatase superfamily" CG1721 27-Aug-18 DroID_v2018_08 "Drer\pgam1b, Drer\bpgm, Drer\pgam2, Drer\pgam1a, Drer\tigara" "Scer\GPM1, Scer\GPM2, Scer\GPM3" - "Xtro\pgam1, Xtro\bpgm, Xtro\pgam2" "Mmus\Bpgm, Mmus\Pgam2, Mmus\Pgam1" "Hsap\BPGM, Hsap\PGAM1, Hsap\PGAM2, Hsap\PGAM4" "embryonic/larval somatic muscle,embryonic myoblast,segment border muscle,A1-7 dorsal acute muscle 1" FBgn0011646 Low Lightener of white http://flybase.org/reports/FBgn0011646 - gene - - - Low - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,suppressor of variegation,dominant" pigment cell FBgn0019810 ftz::RpP1 ftz::RpP1 http://flybase.org/reports/FBgn0019810 - engineered_fusion_gene - - - "ftz::RpA-70, ftz::RpP1" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0013595 l(3)A6-3-56 lethal (3) A6-3-56 http://flybase.org/reports/FBgn0013595 - gene - - - l(3)A6-3-56 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0028411 Nxt1 NTF2-related export protein 1 http://flybase.org/reports/FBgn0028411 protein_coding_gene - negative regulation of innate immune response ; GO:0045824 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype cellular response to starvation ; GO:0009267 | inferred from expression pattern poly(A)+ mRNA export from nucleus ; GO:0016973 | inferred from mutant phenotype nucleoplasm ; GO:0005654 | inferred from direct assay nuclear envelope ; GO:0005635 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "p15, Nxt, dmP15, dNxt, DmNXT1, dmNXT1, nxt1, CG12752, Nxt1, dmNXT" "IPR018222:Nuclear transport factor 2, eukaryote, IPR002075:Nuclear transport factor 2, IPR032710:NTF2-like domain" CG12752 27-Aug-18 DroID_v2018_08 Drer\nxt2 "Scer\MTR2, Scer\NTF2" Cele\nxt-1 Xtro\nxt2 "Mmus\Nxt1, Mmus\Nxt2" "Hsap\NXT1, Hsap\NXT2" "visible,partially lethal - majority die,some die during pupal stage,lethal - all die before end of pupal stage" mesothoracic tergum DRSC04630 I 2.127790577 -0.39622592 -0.673188721 1.417723194 0.176290143 0.803750775 FBgn0023034 l(2)46Ei lethal (2) 46Ei http://flybase.org/reports/FBgn0023034 - gene - - - "S, l(2)46Ei" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,lethal - all die before end of larval stage,some die during larval stage" FBgn0261111 BHD Birt-Hogg-Dube http://flybase.org/reports/FBgn0261111 protein_coding_gene guanyl-nucleotide exchange factor activity ; GO:0005085 | inferred from electronic annotation with InterPro:IPR032035 molecular_function ; GO:0003674 | no biological data available germ-line stem cell population maintenance ; GO:0030718 | inferred from mutant phenotype negative regulation of RNA polymerase I regulatory region sequence-specific DNA binding ; GO:1901840 | inferred from direct assay negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter ; GO:1901837 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay nucleolus ; GO:0005730 | inferred from direct assay "DBHD, BHD, CG8616, CT25610, dFLCN" "IPR021713:Folliculin, IPR032035:Folliculin, C-terminal" CG8616 27-Aug-18 DroID_v2018_08 Drer\flcn Scer\LST7 Cele\flcn-1 Xtro\flcn Mmus\Flcn Hsap\FLCN FBgn0035976 PGRP-LC Peptidoglycan recognition protein LC http://flybase.org/reports/FBgn0035976 protein_coding_gene "zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001965, InterPro:IPR006619 protein dimerization activity ; GO:0046983 | inferred from direct assay peptidoglycan receptor activity ; GO:0016019 | non-traceable author statement N-acetylmuramoyl-L-alanine amidase activity ; GO:0008745 | NOT inferred from key residues signaling pattern recognition receptor activity ; GO:0008329 | traceable author statement peptidoglycan receptor activity ; GO:0016019 | traceable author statement peptidoglycan receptor activity ; GO:0016019 | inferred from mutant phenotype peptidoglycan binding ; GO:0042834 | inferred from sequence or structural similarity with UniProtKB:O76537 peptidoglycan binding ; GO:0042834 | inferred from sequence or structural similarity with PGRP-SC1b peptidoglycan binding ; GO:0042834 | non-traceable author statement peptidoglycan binding ; GO:0042834 | traceable author statement peptidoglycan binding ; GO:0042834 | inferred from direct assay protein binding ; GO:0005515 | inferred from physical interaction with pirk protein dimerization activity ; GO:0046983 | non-traceable author statement" defense response to Gram-negative bacterium ; GO:0050829 | inferred from direct assay positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria ; GO:0006964 | inferred from mutant phenotype positive regulation of antibacterial peptide biosynthetic process ; GO:0006963 | traceable author statement regulation of humoral immune response ; GO:0002920 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | traceable author statement immune response ; GO:0006955 | inferred from mutant phenotype defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype peptidoglycan recognition protein signaling pathway ; GO:0061057 | inferred from mutant phenotype peptidoglycan catabolic process ; GO:0009253 | NOT inferred from key residues antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype innate immune response ; GO:0045087 | traceable author statement positive regulation of antibacterial peptide biosynthetic process ; GO:0006963 | inferred from mutant phenotype phagocytosis ; GO:0006909 | traceable author statement positive regulation of peptidoglycan recognition protein signaling pathway ; GO:0061059 | inferred from genetic interaction with PGRP-SD defense response to virus ; GO:0051607 | inferred from mutant phenotype innate immune response ; GO:0045087 | non-traceable author statement regulation of synaptic plasticity ; GO:0048167 | inferred from mutant phenotype immune response ; GO:0006955 | inferred from sequence or structural similarity with UniProtKB:O76537 response to bacterium ; GO:0009617 | inferred from mutant phenotype peptidoglycan recognition protein signaling pathway ; GO:0061057 | inferred from direct assay regulation of melanization defense response ; GO:0035007 | inferred from mutant phenotype peptidoglycan recognition protein signaling pathway ; GO:0061057 | inferred from genetic interaction with imd antibacterial humoral response ; GO:0019731 | inferred from mutant phenotype cytoplasm ; GO:0005737 | inferred from direct assay integral component of membrane ; GO:0016021 | traceable author statement integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred from direct assay integral component of membrane ; GO:0016021 | non-traceable author statement presynapse ; GO:0098793 | inferred from direct assay apicolateral plasma membrane ; GO:0016327 | inferred from direct assay spanning component of plasma membrane ; GO:0044214 | inferred from sequence model plasma membrane ; GO:0005886 | inferred from direct assay "pgrp-lc, CG4432, ird7, PGRP-LCx, PGRP-LCa, tot, PGRP-LC, (PGRP)-LC, Dm PGRP-LC, PGRPLC, Pgrp-LC, pgrp lc" "IPR002502:N-acetylmuramoyl-L-alanine amidase domain, IPR006619:Peptidoglycan recognition protein family domain, metazoa/bacteria, IPR015510:Peptidoglycan recognition protein, IPR001965:Zinc finger, PHD-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR011011:Zinc finger, FYVE/PHD-type, IPR019787:Zinc finger, PHD-finger" CG4432 27-Aug-18 DroID_v2018_08 "Drer\pglyrp2, Drer\pglyrp5, Drer\pglyrp6" - - "Xtro\pglyrp2, Xtro\pglyrp1, Xtro\pglyrp1" "Mmus\Pglyrp1, Mmus\Pglyrp4, Mmus\Pglyrp3, Mmus\Pglyrp2" "Hsap\PGLYRP4, Hsap\PGLYRP3, Hsap\PGLYRP1, Hsap\PGLYRP2" "immune response defective,visible,short lived,conditional,viable,recessive,fertile,lethal,melanotic mass phenotype" wing FBgn0084374 E-3a Enhancer on chromosome 3-complementation group a http://flybase.org/reports/FBgn0084374 gene - - - E-3a - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing,haltere" FBgn0039094 CG10184 - http://flybase.org/reports/FBgn0039094 protein_coding_gene L-allo-threonine aldolase activity ; GO:0008732 | inferred from biological aspect of ancestor with PANTHER:PTN000033149 glycine biosynthetic process ; GO:0006545 | inferred from biological aspect of ancestor with PANTHER:PTN000033149 threonine catabolic process ; GO:0006567 | inferred from biological aspect of ancestor with PANTHER:PTN000033149 cytosol ; GO:0005829 | inferred from biological aspect of ancestor with PANTHER:PTN000033149 CG10184 "IPR001597:Aromatic amino acid beta-eliminating lyase/threonine aldolase, IPR023603:Threonine aldolase, IPR015421:Pyridoxal phosphate-dependent transferase, major region, subdomain 1, IPR015422:Pyridoxal phosphate-dependent transferase, subdomain 2, IPR015424:Pyridoxal phosphate-dependent transferase" CG10184 27-Aug-18 DroID_v2018_08 Drer\tha1 Scer\GLY1 Cele\R102.4 Xtro\tha1p Mmus\Tha1 - viable FBgn0039227 polybromo polybromo http://flybase.org/reports/FBgn0039227 protein_coding_gene chromatin binding ; GO:0003682 | inferred from electronic annotation with InterPro:IPR001025 "vitelline membrane formation involved in chorion-containing eggshell formation ; GO:0007305 | inferred from mutant phenotype negative regulation of chromatin silencing ; GO:0031936 | inferred from genetic interaction with Pc, Bap170 negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from genetic interaction with Bap170 inferred from genetic interaction with Bap170, e(y)3 inferred from genetic interaction with Bap170, e(y)3 eggshell chorion assembly ; GO:0007306 | inferred from mutant phenotype" polytene chromosome ; GO:0005700 | inferred from direct assay PBAF complex ; GO:0070604 | inferred from direct assay brahma complex ; GO:0035060 | inferred from direct assay "Polybromo, CG11375, baf180, BAF180, anon-WO0140519.158, polybromo, bap180, PB, Pb, Bap180, POLYBROMO" "IPR018359:Bromodomain, conserved site, IPR001025:Bromo adjacent homology (BAH) domain, IPR001487:Bromodomain, IPR009071:High mobility group box domain" CG11375 27-Aug-18 DroID_v2018_08 "Drer\pbrm1l, Drer\pbrm1" "Scer\RSC2, Scer\RSC1, Scer\RSC4" Cele\pbrm-1 Xtro\pbrm1 Mmus\Pbrm1 Hsap\PBRM1 "viable,fertile,visible,dominant,female sterile,homeotic,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,enhancer of variegation" "wing vein,ectopic,vitelline membrane,chorion,adult abdominal segment 6,adult abdominal segment 5" FBgn0029791 CG4096 - http://flybase.org/reports/FBgn0029791 protein_coding_gene "metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR001590, InterPro:IPR002870, InterPro:IPR006586, InterPro:IPR010294 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR002870, InterPro:IPR013273" "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001590, InterPro:IPR002870 negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from genetic interaction with Ras85D inferred from genetic interaction with vn, Krn inferred from genetic interaction with spi, Krn" proteinaceous extracellular matrix ; GO:0005578 | inferred from electronic annotation with InterPro:IPR013273 "CT13580, CG4096" "IPR000884:Thrombospondin type-1 (TSP1) repeat, IPR001590:Peptidase M12B, ADAM/reprolysin, IPR002870:Peptidase M12B, propeptide, IPR010294:ADAM-TS Spacer 1, IPR013273:Peptidase M12B, ADAM-TS, IPR024079:Metallopeptidase, catalytic domain, IPR006586:ADAM, cysteine-rich" CG4096 27-Aug-18 DroID_v2018_08 "Drer\adamts17, Drer\thsd7bb, Drer\adamts18, Drer\adamts8a, Drer\adamtsl3, Drer\spint2, Drer\col6a3, Drer\adamtsl5, Drer\paplna, Drer\adamts10, Drer\adamts12, Drer\adamts7, Drer\adamts1, Drer\adamtsl2, Drer\paplnb, Drer\adamtsl7, Drer\adamts2, Drer\tfpia, Drer\tfpi2, Drer\LOC568792, Drer\adamts15a, Drer\adamts13, Drer\LOC100002059, Drer\adamts6" - "Cele\Y8A9A.2, Cele\T02G6.11, Cele\mig-6, Cele\T19D2.1, Cele\gon-1, Cele\adt-2, Cele\adt-1" "Xtro\adamts13, Xtro\adamts15, Xtro\adamtsl4, Xtro\adamts14, Xtro\adamts6, Xtro\adamts9, Xtro\adamts3, Xtro\adamts16, Xtro\adamts18, Xtro\adamts20, Xtro\adamts12, Xtro\spint2, Xtro\papln, Xtro\adamts10, Xtro\adamts7, Xtro\tfpi2, Xtro\adamts2, Xtro\adamts17" "Mmus\Adamts19, Mmus\Adamts20, Mmus\Adamts18, Mmus\Adamts3, Mmus\Adamts15, Mmus\Col6a3, Mmus\Adamts13, Mmus\Adamts9, Mmus\Adamts17, Mmus\Adamts12, Mmus\Adamts16, Mmus\Adamts8, Mmus\Adamts10, Mmus\Tfpi, Mmus\Sspo, Mmus\Thsd7a, Mmus\Adamts14, Mmus\Thsd4, Mmus\Adamts6, Mmus\Adamtsl5, Mmus\Adamts2, Mmus\Adamts1, Mmus\Adamtsl4, Mmus\Adamts4, Mmus\Adamts7, Mmus\Adamtsl1, Mmus\Papln, Mmus\Tfpi2" "Hsap\ADAMTS12, Hsap\SPINT3, Hsap\PAPLN, Hsap\ADAMTS9, Hsap\ADAMTS18, Hsap\ADAMTS7, Hsap\ADAMTS14, Hsap\ADAMTS10, Hsap\ADAMTS6, Hsap\ADAMTS3, Hsap\ADAMTSL5, Hsap\ADAMTSL1, Hsap\TFPI2, Hsap\COL6A3, Hsap\ADAMTS2, Hsap\ADAMTS13, Hsap\TFPI, Hsap\ADAMTS20, Hsap\ADAMTS4, Hsap\THSD4, Hsap\ADAMTSL4, Hsap\ADAMTS1, Hsap\ADAMTS19, Hsap\THSD7B, Hsap\ADAMTS15, Hsap\ADAMTS17, Hsap\ADAMTS16, Hsap\ADAMTS8" "viable,fertile,visible" "wing vein,ectopic,wing" FBgn0039355 CG4730 - http://flybase.org/reports/FBgn0039355 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012934 DNA binding ; GO:0003677 | inferred from direct assay - nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR012934 CG4730 "IPR012934:Zinc finger, AD-type, IPR013083:Zinc finger, RING/FYVE/PHD-type, IPR013087:Zinc finger C2H2-type" CG4730 27-Aug-18 DroID_v2018_08 "Drer\klf12b, Drer\klf12a, Drer\vezf1a, Drer\znf281a, Drer\si:ch211-166g5.4, Drer\klf3, Drer\LOC100535691, Drer\znf740a, Drer\si:dkey-262g12.7, Drer\znf281b, Drer\znf740b, Drer\LOC101882721, Drer\vezf1b" Scer\AZF1 "Cele\eor-1, Cele\snai-1, Cele\ZK686.5, Cele\ztf-6" Xtro\zfp1 "Mmus\Zfp1, Mmus\Klf8, Mmus\Maz, Mmus\Zfp637, Mmus\Klf12, Mmus\Zfp362, Mmus\Klf3, Mmus\Vezf1, Mmus\Zfp281" "Hsap\ZNF362, Hsap\KLF8, Hsap\KLF3, Hsap\ZFP1, Hsap\MAZ, Hsap\ZNF32, Hsap\ZNF281, Hsap\ZNF740, Hsap\VEZF1, Hsap\KLF12" "viable,fertile" FBgn0044051 Ilp1 Insulin-like peptide 1 http://flybase.org/reports/FBgn0044051 protein_coding_gene hormone activity ; GO:0005179 | inferred from electronic annotation with InterPro:IPR016179 insulin receptor binding ; GO:0005158 | inferred from sequence or structural similarity with HGNC:6081 regulation of insulin receptor signaling pathway ; GO:0046626 | inferred from biological aspect of ancestor with PANTHER:PTN001414741 insulin receptor signaling pathway ; GO:0008286 | inferred from sequence or structural similarity with HGNC:6081 regulation of glucose metabolic process ; GO:0010906 | inferred from biological aspect of ancestor with PANTHER:PTN001414741 extracellular space ; GO:0005615 | inferred from sequence or structural similarity with HGNC:6081 "dilp, DILP, dilp-1, Dilp, dilp1, Dilp 1, DILP1, CG14173, Ilp1, Ilp, Dilp-1, Dilp1, Ilp-1, ilp1, DILP-1, dILP1" "IPR016179:Insulin-like, IPR022352:Insulin family, IPR022353:Insulin, conserved site" CG14173 27-Aug-18 DroID_v2018_08 - - Cele\ins-1 - - - "viable,small body" FBgn0267318 lncRNA:CR45754 - http://flybase.org/reports/FBgn0267318 non_protein_coding_gene - - - CR45754 - CR45754 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0066132 E(sda)A E(sda)A http://flybase.org/reports/FBgn0066132 gene molecular_function ; GO:0003674 | no biological data available mechanosensory behavior ; GO:0007638 | inferred from mutant phenotype response to mechanical stimulus ; GO:0009612 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "E(sda)A, Line A" - - 27-Aug-18 DroID_v2018_08 - - - - - - bang sensitive FBgn0058116 CG40116 - http://flybase.org/reports/FBgn0058116 protein_coding_gene - - - CG40116 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0029909 mAChR-C "muscarinic Acetylcholine Receptor, C-type" http://flybase.org/reports/FBgn0029909 protein_coding_gene "G-protein coupled acetylcholine receptor activity ; GO:0016907 | inferred from direct assay dopamine neurotransmitter receptor activity, coupled via Gs ; GO:0001588 | inferred from biological aspect of ancestor with PANTHER:PTN001205456 G-protein coupled amine receptor activity ; GO:0008227 | inferred from sequence or structural similarity" G-protein coupled acetylcholine receptor signaling pathway ; GO:0007213 | inferred from direct assay G-protein coupled receptor signaling pathway ; GO:0007186 | inferred from sequence or structural similarity "integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR017452 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity integral component of plasma membrane ; GO:0005887 | inferred by curator from GO:0016907" "CG12796, mAChR-C" "IPR000276:G protein-coupled receptor, rhodopsin-like, IPR017452:GPCR, rhodopsin-like, 7TM" CG12796 27-Aug-18 DroID_v2018_08 Drer\htr6 - "Cele\F57C9.6, Cele\C01F1.4, Cele\F59D12.1, Cele\F36D4.4, Cele\tyra-2" - "Mmus\Gpr119, Mmus\Chrm3, Mmus\Gpr12" "Hsap\GPR12, Hsap\GPR119, Hsap\CHRM3" viable FBgn0058158 CG40158 - http://flybase.org/reports/FBgn0058158 protein_coding_gene - - - CG40158 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0266818 lncRNA:CR45280 - http://flybase.org/reports/FBgn0266818 non_protein_coding_gene - - - CR45280 - CR45280 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0069301 XRCC4 XRCC4 http://flybase.org/reports/FBgn0069301 gene protein binding ; GO:0005515 | inferred from physical interaction with Lig4 - - XRCC4 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085551 CG40995 - http://flybase.org/reports/FBgn0085551 protein_coding_gene - - - CG40995 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060547 l(3)S098614 lethal (3) S098614 http://flybase.org/reports/FBgn0060547 gene - - - "0986/14, l(3)S098614" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0266806 asRNA:CR45268 - http://flybase.org/reports/FBgn0266806 non_protein_coding_gene - - - CR45268 - CR45268 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004984 blu blunt http://flybase.org/reports/FBgn0004984 - gene - - - blu - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,recessive" wing FBgn0038330 CG14868 - http://flybase.org/reports/FBgn0038330 protein_coding_gene - - - CG14868 IPR019179:Coiled-coil domain-containing protein 149-A CG14868 27-Aug-18 DroID_v2018_08 "Drer\ccdc149a, Drer\ccdc149b" - Cele\ccdc-149 Xtro\ccdc149 Mmus\Ccdc149 Hsap\CCDC149 DRSC14991 I 1.010259923 1.533437542 0.94208393 0.962579695 -0.118877228 0.478200638 FBgn0002797 ms(1)7 male sterile (1) 7 http://flybase.org/reports/FBgn0002797 - gene - - - ms(1)7 - - 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,female fertile,viable" FBgn0259564 B0578 - http://flybase.org/reports/FBgn0259564 gene - - - B0578 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0025827 CG6421 - http://flybase.org/reports/FBgn0025827 FBgn0034163 protein_coding_gene lysozyme activity ; GO:0003796 | inferred from electronic annotation with InterPro:IPR008597 - - "EG:EG0003.8, CG6421" "IPR008597:Destabilase, IPR023346:Lysozyme-like domain" CG6421 27-Aug-18 DroID_v2018_08 - - "Cele\ilys-4, Cele\ilys-1, Cele\ilys-5, Cele\ilys-2, Cele\ilys-3, Cele\ilys-6" - - - viable FBgn0017376 l(1)HM452 lethal (1) HM452 http://flybase.org/reports/FBgn0017376 - gene - - - l(1)HM452 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0038123 CG8508 - http://flybase.org/reports/FBgn0038123 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "anon-WO0140519.216, CG8508" - CG8508 27-Aug-18 DroID_v2018_08 "Drer\ovgp1, Drer\chia.5, Drer\si:ch211-226m16.2, Drer\chia.2" Scer\CTS2 - "Xtro\chia, Xtro\chit1, Xtro\LOC548945, Xtro\ctbs" "Mmus\Chil1, Mmus\Ovgp1, Mmus\Chil3, Mmus\Chia1, Mmus\Ctbs, Mmus\Chit1, Mmus\Chil5, Mmus\Chil6, Mmus\Chil4" "Hsap\CHI3L1, Hsap\CHI3L2, Hsap\CHIT1, Hsap\OVGP1, Hsap\CHIA" viable FBgn0004522 l(4)102CDf lethal (4) 102CDf http://flybase.org/reports/FBgn0004522 - gene - - - "l(4)CDf, l(4)7, l(4)102CDf" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,lethal - all die before end of embryonic stage,some die during embryonic stage" FBgn0013295 M(2)OE227 M(2)OE227 http://flybase.org/reports/FBgn0013295 - gene - - - M(2)OE227 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001468 l(1)8 lethal (1) 8 http://flybase.org/reports/FBgn0001468 - gene - - - "tsl(1)8, l(1)8" - - 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,heat sensitive,lethal,male" "spermatid,primary spermatocyte cyst,spermatocyte" FBgn0264565 lncRNA:CR43937 - http://flybase.org/reports/FBgn0264565 non_protein_coding_gene - - - CR43937 - CR43937 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039801 Npc2h Niemann-Pick type C-2h http://flybase.org/reports/FBgn0039801 protein_coding_gene lipid antigen binding ; GO:0030882 | inferred from direct assay lipoteichoic acid binding ; GO:0070891 | inferred from direct assay lipopolysaccharide binding ; GO:0001530 | inferred from direct assay peptidoglycan binding ; GO:0042834 | inferred from direct assay sterol binding ; GO:0032934 | inferred from sequence or structural similarity with HGNC:14537 intracellular cholesterol transport ; GO:0032367 | inferred from electronic annotation with InterPro:IPR033916 hemolymph coagulation ; GO:0042381 | inferred from expression pattern sterol transport ; GO:0015918 | inferred from sequence or structural similarity with Npc2a extracellular region ; GO:0005576 | inferred from direct assay extracellular space ; GO:0005615 | inferred from direct assay "DmML1A, BcDNA:RH68460, BcDNA:RH04252, BcDNA:GH26608, npc2h, Npc2h, CG11315" "IPR003172:MD-2-related lipid-recognition domain, IPR014756:Immunoglobulin E-set, IPR033916:ML domain, Npc2 like" CG11315 27-Aug-18 DroID_v2018_08 "Drer\npc2, Drer\zgc:193725" Scer\NPC2 Cele\heh-1 Xtro\npc2 Mmus\Npc2 Hsap\NPC2 viable FBgn0266670 Sec5 Secretory 5 http://flybase.org/reports/FBgn0266670 protein_coding_gene Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab30 Rab GTPase binding ; GO:0017137 | inferred from physical interaction with Rab11 "transcytosis ; GO:0045056 | inferred from mutant phenotype negative regulation of gene expression ; GO:0010629 | inferred from direct assay vesicle-mediated transport ; GO:0016192 | inferred from mutant phenotype protein localization to cell cortex ; GO:0072697 | inferred from mutant phenotype Golgi to plasma membrane transport ; GO:0006893 | inferred from mutant phenotype endocytic recycling ; GO:0032456 | inferred from mutant phenotype synaptic vesicle targeting ; GO:0016080 | non-traceable author statement innate immune response ; GO:0045087 | inferred from direct assay neurotransmitter secretion ; GO:0007269 | non-traceable author statement positive regulation of Golgi vesicle fusion to target membrane ; GO:0048215 | inferred from mutant phenotype protein localization to plasma membrane ; GO:0072659 | inferred from mutant phenotype synaptic vesicle docking ; GO:0016081 | non-traceable author statement exocyst assembly ; GO:0001927 | inferred from biological aspect of ancestor with PANTHER:PTN000315823 border follicle cell migration ; GO:0007298 | inferred from mutant phenotype mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype cellularization ; GO:0007349 | inferred from mutant phenotype Golgi to plasma membrane protein transport ; GO:0043001 | inferred from mutant phenotype vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity branch fusion, open tracheal system ; GO:0035147 | inferred from mutant phenotype protein localization to adherens junction ; GO:0071896 | inferred from mutant phenotype oocyte development ; GO:0048599 | inferred from mutant phenotype" cell cortex ; GO:0005938 | inferred from direct assay annulate lamellae ; GO:0005642 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay exocyst ; GO:0000145 | inferred from direct assay exocyst ; GO:0000145 | inferred from biological aspect of ancestor with PANTHER:PTN000315823 exocyst ; GO:0000145 | non-traceable author statement exocyst ; GO:0000145 | inferred from sequence or structural similarity cytoplasm ; GO:0005737 | inferred from direct assay clathrin-coated vesicle ; GO:0030136 | inferred from direct assay recycling endosome ; GO:0055037 | inferred from direct assay subapical complex ; GO:0035003 | inferred from direct assay rhabdomere ; GO:0016028 | inferred from direct assay "sec5, Sec5, SEC5, Sec-5, Sec5p, dsec5, CG8843" "IPR002909:IPT domain, IPR013783:Immunoglobulin-like fold, IPR014756:Immunoglobulin E-set, IPR029175:Exocyst complex component EXOC2/Sec5" CG8843 27-Aug-18 DroID_v2018_08 Drer\exoc2 Scer\SEC5 Cele\sec-5 Xtro\exoc2 Mmus\Exoc2 Hsap\EXOC2 FBgn0021789 l(2)rH280 lethal (2) rH280 http://flybase.org/reports/FBgn0021789 - gene - - - l(2)rH280 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0069071 zih ziehharmonika http://flybase.org/reports/FBgn0069071 gene molecular_function ; GO:0003674 | no biological data available "anterior/posterior axis specification, embryo ; GO:0008595 | inferred from mutant phenotype" cellular_component ; GO:0005575 | no biological data available zih - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,lethal - all die before end of embryonic stage,germline clone,non-rescuable maternal effect,recessive,some die during embryonic stage,maternal effect" "embryonic head,germline clone,maternal effect,filzkorper,embryonic segment" FBgn0032472 CG9928 - http://flybase.org/reports/FBgn0032472 protein_coding_gene - - - "CT27834, BcDNA:RH70154, CG9928" - CG9928 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0067056 Q7 Q7 http://flybase.org/reports/FBgn0067056 gene - - - Q7 - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,lethal,viable" eye FBgn0031410 CG17237 - http://flybase.org/reports/FBgn0031410 protein_coding_gene "ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity" - myosin complex ; GO:0016459 | inferred from sequence or structural similarity "DmAAF51272, BcDNA:AT15471, CG17237, ELC4" IPR011992:EF-hand domain pair CG17237 27-Aug-18 DroID_v2018_08 "Drer\mylz3, Drer\cmlc1, Drer\zgc:153867, Drer\zgc:163073, Drer\myl4, Drer\myl13, Drer\myl6, Drer\myl1" Scer\MLC1 "Cele\cal-7, Cele\mlc-5, Cele\mlc-7, Cele\mlc-6" "Xtro\myl1, Xtro\myl4, Xtro\myl3, Xtro\myl6" "Mmus\Myl3, Mmus\Myl6, Mmus\Myl1, Mmus\Myl4, Mmus\Myl6b" "Hsap\MYL3, Hsap\MYL1, Hsap\MYL6, Hsap\MYL6B, Hsap\MYL4" FBgn0065614 l(2)SH0824 lethal (2) SH0824 http://flybase.org/reports/FBgn0065614 gene - - - "l(2)SH0824, l(2)SH2 0824" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0264090 CG43759 - http://flybase.org/reports/FBgn0264090 protein_coding_gene - inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype - "CG43759, CG32541, CG14188, EP(X)1644, LD15404, CG12527, CG42506" - CG43759 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0066292 CheB42c Chemosensory protein B 42c http://flybase.org/reports/FBgn0066292 protein_coding_gene lipid binding ; GO:0008289 | inferred from sequence alignment with HGNC:14537 sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence or structural similarity with CheB42a detection of pheromone ; GO:0043695 | inferred from expression pattern extracellular region ; GO:0005576 | inferred from sequence model extracellular space ; GO:0005615 | inferred from sequence or structural similarity with CheB42a "CG15241, CG33350, CheB42c" "IPR010512:Protein of unknown function DUF1091, IPR006601:Uncharacterised protein family DM11, Drosophila melanogaster" CG33350 27-Aug-18 DroID_v2018_08 - - - - - - "viable,lethal" FBgn0023058 l(1)2Ed lethal (1) 2Ed http://flybase.org/reports/FBgn0023058 - gene - - - "E3/34.12, l(1)2Ed" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0000656 fil fine lash http://flybase.org/reports/FBgn0000656 - gene - - - fil - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile,visible" "macrochaeta,eye" FBgn0266861 lncRNA:CR45322 - http://flybase.org/reports/FBgn0266861 non_protein_coding_gene - - - CR45322 - CR45322 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0032374 CG14931 - http://flybase.org/reports/FBgn0032374 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14931 - CG14931 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0036449 bmm brummer http://flybase.org/reports/FBgn0036449 protein_coding_gene triglyceride lipase activity ; GO:0004806 | inferred from direct assay lipid metabolic process ; GO:0006629 | inferred from mutant phenotype lipid catabolic process ; GO:0016042 | inferred from mutant phenotype determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype sleep ; GO:0030431 | inferred from expression pattern positive regulation of lipid storage ; GO:0010884 | inferred from direct assay lipid homeostasis ; GO:0055088 | inferred from mutant phenotype triglyceride mobilization ; GO:0006642 | inferred from mutant phenotype triglyceride catabolic process ; GO:0019433 | inferred from mutant phenotype cytosol ; GO:0005829 | inferred from direct assay membrane ; GO:0016020 | inferred from biological aspect of ancestor with PANTHER:PTN000274414 lipid particle ; GO:0005811 | inferred from direct assay "bmm, CG5295, ATGL, Atgl, Bmm, BMM, ATGL/bmm" "IPR002641:Patatin-like phospholipase domain, IPR016035:Acyl transferase/acyl hydrolase/lysophospholipase, IPR033562:Patatin-like phospholipase domain-containing protein" CG5295 27-Aug-18 DroID_v2018_08 "Drer\pnpla3, Drer\pnpla2" - "Cele\B0524.2, Cele\atgl-1, Cele\D1054.1" "Xtro\pnpla2, Xtro\pnpla3, Xtro\pnpla4" "Mmus\Pnpla2, Mmus\Pnpla3, Mmus\Pnpla5, Mmus\Pnpla1" "Hsap\PNPLA4, Hsap\PNPLA3, Hsap\PNPLA5, Hsap\PNPLA2, Hsap\PNPLA1" "viable,short lived,recessive,long lived,stress response defective,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage,visible" "adult fat body,embryonic/larval midgut,lipid droplet & larval oenocyteppl.PP,lipid droplet & larval oenocyteLsp2.PH,chaeta,supernumerary" FBgn0082686 E(ftz)20 E(ftz)20 http://flybase.org/reports/FBgn0082686 gene - - - "20, E(ftz)20" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005414 l(1)adl3 lethal (1) adl3 http://flybase.org/reports/FBgn0005414 - gene - - - "l(1)adl-3, l(1)adl3" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,heat sensitive,female sterile,short lived,gravitaxis defective,phototaxis defective,behavior defective" FBgn0039069 CG6763 - http://flybase.org/reports/FBgn0039069 protein_coding_gene metalloendopeptidase activity ; GO:0004222 | inferred from electronic annotation with InterPro:IPR001506 zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR006026 "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001506, InterPro:IPR006026" - CG6763 "IPR001506:Peptidase M12A, IPR006026:Peptidase, metallopeptidase, IPR024079:Metallopeptidase, catalytic domain, IPR034035:Astacin-like metallopeptidase domain" CG6763 27-Aug-18 DroID_v2018_08 "Drer\c6ast4, Drer\he2, Drer\si:cabz01033205.3, Drer\LOC797085, Drer\mep1a.1, Drer\neto1l, Drer\si:ch211-167j6.5, Drer\mep1a.2, Drer\bmp1a, Drer\he1a, Drer\he1b, Drer\csmd1a, Drer\c6ast1, Drer\mep1b, Drer\npsn, Drer\LOC100003133, Drer\cdcp2, Drer\bmp1b, Drer\tnfaip6, Drer\tll1, Drer\si:ch73-40a17.3, Drer\c6ast3, Drer\neto1, Drer\neto2b" - "Cele\nas-2, Cele\Y19D10A.6, Cele\nas-9, Cele\nas-39, Cele\nas-13, Cele\ZC116.3, Cele\nas-6, Cele\nas-8, Cele\nas-15, Cele\nas-33, Cele\nas-14, Cele\nas-5, Cele\nas-4, Cele\nas-7, Cele\nas-1, Cele\nas-12" "Xtro\tnfaip6, Xtro\LOC100489456, Xtro\mep1a, Xtro\uvs.2, Xtro\accs, Xtro\cubn, Xtro\bmp1, Xtro\LOC100492324, Xtro\tll1, Xtro\mep1b, Xtro\tll2" "Mmus\Tnfaip6, Mmus\Adgrg6, Mmus\Tll2, Mmus\Cdcp2, Mmus\Astl, Mmus\Tll1, Mmus\Neto1, Mmus\Neto2, Mmus\Bmp1, Mmus\Mfrp, Mmus\Mep1b, Mmus\Mep1a, Mmus\Cubn" "Hsap\TLL1, Hsap\CUBN, Hsap\MEP1B, Hsap\ASTL, Hsap\CDCP2, Hsap\MEP1A, Hsap\TLL2, Hsap\NETO1, Hsap\BMP1, Hsap\NETO2, Hsap\MFRP, Hsap\ADGRG6, Hsap\TNFAIP6" viable FBgn0019726 l(2)46CFb lethal (2) 46CFb http://flybase.org/reports/FBgn0019726 - gene - - - "1.11, l(2)46CFb" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0029022 l(3)77ABj lethal (3) 77ABj http://flybase.org/reports/FBgn0029022 gene - - - l(3)77ABj - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of prepupal stage,recessive,some die during prepupal stage" FBgn0062678 EP2087 EP2087 http://flybase.org/reports/FBgn0062678 gene - - - "EP(2)2087, EP2087" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0053145 GalT1 "beta1,3-galactosyltransferase 1" http://flybase.org/reports/FBgn0053145 protein_coding_gene "beta-1,3-galactosyltransferase activity ; GO:0048531 | inferred from direct assay" protein N-linked glycosylation ; GO:0006487 | inferred from direct assay membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR002659 "CG33145, CG8976, GalT1, dbeta3GnT" "IPR002659:Glycosyl transferase, family 31" CG33145 27-Aug-18 DroID_v2018_08 "Drer\b3gnt7, Drer\b3galt1a, Drer\si:dkeyp-98a7.1, Drer\b3galnt2, Drer\b3gnt9, Drer\LOC565422, Drer\b3gnt3, Drer\si:ch211-126g16.11, Drer\b3gnt2a, Drer\b3gnt2b, Drer\b3galt1b, Drer\LOC100535930, Drer\zgc:194330, Drer\b3gnt2l, Drer\b3gnt7l, Drer\b3galt2, Drer\si:dkey-160o24.3, Drer\zgc:86586, Drer\zgc:194551, Drer\b3gnt5a, Drer\si:dkey-175m17.6, Drer\b3gnt5b" - "Cele\B0024.15, Cele\bus-2, Cele\E03H4.11, Cele\bus-17, Cele\C47F8.5, Cele\sqv-2" "Xtro\b3gnt5, Xtro\LOC100487553, Xtro\LOC100494986, Xtro\b3galt2, Xtro\LOC100493833, Xtro\b3galt4, Xtro\LOC100489267, Xtro\b3gnt3, Xtro\b3gnt6, Xtro\b3gnt2, Xtro\b3galt1, Xtro\b3gnt3, Xtro\b3galnt2, Xtro\LOC100494668, Xtro\b3gnt4" "Mmus\B3gnt6, Mmus\B3gnt3, Mmus\B3gnt8, Mmus\B3galnt1, Mmus\B3gnt5, Mmus\B3galnt2, Mmus\B3gnt9, Mmus\B3gnt4, Mmus\B3gnt2, Mmus\B3galt5, Mmus\B3galt2, Mmus\B3galt4, Mmus\B3galt1, Mmus\B3gnt7" "Hsap\B3GALT2, Hsap\B3GNT9, Hsap\B3GNT8, Hsap\B3GNT7, Hsap\B3GALNT1, Hsap\B3GALT4, Hsap\B3GALT5, Hsap\B3GALT1, Hsap\B3GNT6, Hsap\B3GNT3, Hsap\B3GALNT2, Hsap\B3GNT5, Hsap\B3GNT4, Hsap\B3GNT2" "viable,fertile" FBgn0046670 anon-38C.25 anon-38C.25 http://flybase.org/reports/FBgn0046670 gene - - - "38C.25, anon-38C.25" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0004014 wi witty eye http://flybase.org/reports/FBgn0004014 - gene - - - wi - - 27-Aug-18 DroID_v2018_08 - - - - - - "eye,ommatidium,vibrissae" FBgn0083979 Ir10a Ionotropic receptor 10a http://flybase.org/reports/FBgn0083979 protein_coding_gene ligand-gated ion channel activity ; GO:0015276 | inferred from sequence model detection of chemical stimulus ; GO:0009593 | inferred from sequence or structural similarity with Ir92a integral component of membrane ; GO:0016021 | inferred from sequence model "Ir10a, CG12623, CG12624, CG34143, DmelIR10a, IR10a" - CG34143 27-Aug-18 DroID_v2018_08 - - - - - "Hsap\GRID1, Hsap\GRID2" viable FBgn0052254 CG32254 - http://flybase.org/reports/FBgn0052254 protein_coding_gene - - - "BcDNA:RH01388, CG32254" - - 27-Aug-18 DroID_v2018_08 - - - - - - DRSC21905 K 0.77029418 -0.079294308 -0.352191149 -0.541997711 1.980851792 0.120688902 FBgn0000433 depl depressed-like http://flybase.org/reports/FBgn0000433 - gene - - - "dep[r], depl" - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,partially lethal - majority live,body color defective" "wing,macrochaeta" FBgn0260299 GSd498 - http://flybase.org/reports/FBgn0260299 gene - - - GSd498 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0266023 lncRNA:CR44788 - http://flybase.org/reports/FBgn0266023 non_protein_coding_gene - - - "CR44788, lincRNA.12" - CR44788 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0010865 l(3)05408 lethal (3) 05408 http://flybase.org/reports/FBgn0010865 FBgn0011308 gene - - - "l(3)j1B3, l(3)05408" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0040394 CG16903 - http://flybase.org/reports/FBgn0040394 protein_coding_gene protein kinase binding ; GO:0019901 | inferred from electronic annotation with InterPro:IPR015429 cyclin-dependent protein serine/threonine kinase regulator activity ; GO:0016538 | inferred from biological aspect of ancestor with PANTHER:PTN000002458 positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from biological aspect of ancestor with PANTHER:PTN000002458 positive regulation of cyclin-dependent protein serine/threonine kinase activity ; GO:0045737 | inferred from biological aspect of ancestor with PANTHER:PTN000002458 neurogenesis ; GO:0022008 | inferred from mutant phenotype positive regulation of phosphorylation of RNA polymerase II C-terminal domain ; GO:1901409 | inferred from biological aspect of ancestor with PANTHER:PTN000002458 nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000002458 cyclin-dependent protein kinase holoenzyme complex ; GO:0000307 | inferred from biological aspect of ancestor with PANTHER:PTN000002458 "EG:67A9.2, anon-WO03040301.211, CG16903" "IPR006671:Cyclin, N-terminal, IPR013763:Cyclin-like, IPR015429:Cyclin L/T, IPR004367:Cyclin, C-terminal domain" CG16903 27-Aug-18 DroID_v2018_08 "Drer\ccnl1b, Drer\ccnl1a" "Scer\BUR2, Scer\SSN8" "Cele\cit-1.2, Cele\cyl-1" "Xtro\ccnl2, Xtro\ccnl1" "Mmus\Ccnl1, Mmus\Ccnl2" "Hsap\CCNL2, Hsap\CCNL1" "lethal,neuroanatomy defective" "embryonic/larval neuroblast,ganglion mother cell" FBgn0065836 l(2)SH0336 lethal (2) SH0336 http://flybase.org/reports/FBgn0065836 gene - - - "l(2)SH0336, l(2)SH2 0336" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0037232 Suv3 Suv3 helicase http://flybase.org/reports/FBgn0037232 protein_coding_gene DNA helicase activity ; GO:0003678 | inferred from sequence or structural similarity with UniProtKB:Q8IYB8 DNA binding ; GO:0003677 | inferred from sequence or structural similarity with UniProtKB:Q8IYB8 ATP-dependent RNA helicase activity ; GO:0004004 | inferred from biological aspect of ancestor with PANTHER:PTN002281432 RNA catabolic process ; GO:0006401 | inferred from biological aspect of ancestor with PANTHER:PTN002281432 DNA duplex unwinding ; GO:0032508 | inferred from sequence or structural similarity with UniProtKB:Q8IYB8 mitochondrial mRNA polyadenylation ; GO:0097222 | inferred from mutant phenotype regulation of mitochondrial mRNA stability ; GO:0044528 | inferred from mutant phenotype positive regulation of mitochondrial translation ; GO:0070131 | inferred from mutant phenotype mitochondrial RNA processing ; GO:0000963 | inferred from mutant phenotype oxidative phosphorylation ; GO:0006119 | inferred from mutant phenotype respiratory electron transport chain ; GO:0022904 | inferred from mutant phenotype mitochondrial tRNA processing ; GO:0090646 | inferred from mutant phenotype mitochondrion ; GO:0005739 | inferred from direct assay mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:Q8IYB8 mitochondrial degradosome ; GO:0045025 | inferred from biological aspect of ancestor with PANTHER:PTN000252978 "CG9791, Suv3, dmsuv3, SUV3" "IPR001650:Helicase, C-terminal, IPR014001:Helicase superfamily 1/2, ATP-binding domain, IPR027417:P-loop containing nucleoside triphosphate hydrolase, IPR022192:Mitochondrial degradasome RNA helicase subunit, C-terminal domain" CG9791 27-Aug-18 DroID_v2018_08 Drer\supv3l1 Scer\SUV3 Cele\C08F8.2 Xtro\supv3l1 Mmus\Supv3l1 Hsap\SUPV3L1 "visible,partially lethal - majority die,some die during pupal stage" trichogen cell DRSC12335 K -0.201561247 -0.564395001 -1.280551535 0.37742834 1.946842975 0.058877952 FBgn0041245 Gr39b Gustatory receptor 39b http://flybase.org/reports/FBgn0041245 protein_coding_gene sweet taste receptor activity ; GO:0033041 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 taste receptor activity ; GO:0008527 | non-traceable author statement olfactory receptor activity ; GO:0004984 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 taste receptor activity ; GO:0008527 | inferred from sequence or structural similarity sensory perception of pain ; GO:0019233 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of bitter taste ; GO:0050913 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of taste ; GO:0050909 | non-traceable author statement response to carbon dioxide ; GO:0010037 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 male courtship behavior ; GO:0008049 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 chemosensory behavior ; GO:0007635 | inferred from biological aspect of ancestor with PANTHER:PTN001080220 sensory perception of taste ; GO:0050909 | inferred from sequence or structural similarity integral component of membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR013604 axon ; GO:0030424 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 neuronal cell body ; GO:0043025 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 dendrite ; GO:0030425 | inferred from biological aspect of ancestor with PANTHER:PTN000475107 integral component of membrane ; GO:0016021 | non-traceable author statement "Gr39D1, 39D1, 39D.1, CG31620, GR39D.1, Gr39b, GR39b" IPR013604:7TM chemoreceptor CG31620 27-Aug-18 DroID_v2018_08 - - "Cele\lite-1, Cele\gur-3" - - - viable DRSC01848 IK -1.956293302 1.418062416 0.49927517 -0.068433708 -1.969369262 -0.498308641 FBgn0050049 CG30049 - http://flybase.org/reports/FBgn0050049 protein_coding_gene - - cellular_component ; GO:0005575 | no biological data available "CG30049, CG30049-PA" IPR007484:Peptidase M28 CG30049 27-Aug-18 DroID_v2018_08 Drer\LOC100330918 "Scer\YDR415C, Scer\VPS70, Scer\APE3, Scer\PFF1" "Cele\B0495.7, Cele\C44B7.11" Xtro\ermp1 Mmus\Ermp1 Hsap\ERMP1 viable DRSC21345 I 0.419832993 -1.923645196 0.164386021 1.429592861 0.038733218 -0.622010035 FBgn0046630 anon-38E.6 anon-38E.6 http://flybase.org/reports/FBgn0046630 gene - - - "38E.6, anon-38E.6" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0066341 mirta mirta http://flybase.org/reports/FBgn0066341 gene molecular_function ; GO:0003674 | no biological data available learning or memory ; GO:0007611 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mirta - - 27-Aug-18 DroID_v2018_08 - - - - - - memory defective FBgn0002648 mar metaphase arrest http://flybase.org/reports/FBgn0002648 - gene molecular_function ; GO:0003674 | no biological data available mitotic nuclear division ; GO:0007067 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mar - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,mitotic cell cycle defective,lethal - all die before end of larval stage,recessive,some die during larval stage" FBgn0028569 robl37BC robl37BC http://flybase.org/reports/FBgn0028569 protein_coding_gene "dynein intermediate chain binding ; GO:0045505 | inferred from biological aspect of ancestor with PANTHER:PTN000081506 ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity dynein intermediate chain binding ; GO:0045505 | inferred from sequence or structural similarity with robl" microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity with robl microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity microtubule-based movement ; GO:0007018 | inferred from biological aspect of ancestor with PANTHER:PTN000081506 dynein complex ; GO:0030286 | inferred from sequence or structural similarity with robl dynein complex ; GO:0030286 | inferred from biological aspect of ancestor with PANTHER:PTN000081506 dynein complex ; GO:0030286 | inferred from sequence or structural similarity "CG15171, robl37BC, Robl37BC" IPR004942:Roadblock/LAMTOR2 domain CG15171 27-Aug-18 DroID_v2018_08 "Drer\dynlrb1, Drer\si:ch211-147k9.8" - Cele\dyrb-1 "Xtro\dynlrb1, Xtro\dynlrb2" "Mmus\Dynlrb1, Mmus\Dynlrb2" "Hsap\DYNLRB1, Hsap\DYNLRB2" viable FBgn0015350 CG10349 - http://flybase.org/reports/FBgn0015350 - protein_coding_gene - - - "CG-CG10349, CT29078, II, anon-89Ea, CG10349" - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible" trichogen cell FBgn0065594 l(2)SH0895 lethal (2) SH0895 http://flybase.org/reports/FBgn0065594 gene - - - "l(2)SH0895, l(2)SH2 0895" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0060854 l(3)S048319 lethal (3) S048319 http://flybase.org/reports/FBgn0060854 gene - - - "0483/19, l(3)S048319" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive" FBgn0025147 ms(2)A9 ms(2)A9 http://flybase.org/reports/FBgn0025147 - gene - - - ms(2)A9 - - 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,recessive" FBgn0016698 Ptpa Phosphotyrosyl phosphatase activator http://flybase.org/reports/FBgn0016698 - protein_coding_gene protein tyrosine phosphatase activator activity ; GO:0008160 | inferred from biological aspect of ancestor with PANTHER:PTN000000630 peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from biological aspect of ancestor with PANTHER:PTN000000630 regulation of asymmetric protein localization involved in cell fate determination ; GO:1904785 | inferred from mutant phenotype basal protein localization ; GO:0045175 | inferred from mutant phenotype mitotic spindle organization in nucleus ; GO:0030472 | inferred from biological aspect of ancestor with PANTHER:PTN000000630 nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN000000630 protein phosphatase type 2A complex ; GO:0000159 | inferred from sequence or structural similarity with UniProtKB:Q15257 protein phosphatase type 2A complex ; GO:0000159 | inferred from biological aspect of ancestor with PANTHER:PTN000000630 "PTPA, DPTPA, CG3289, Ptpa" "IPR004327:Phosphotyrosyl phosphatase activator, PTPA" CG3289 27-Aug-18 DroID_v2018_08 Drer\ppp2r4 "Scer\RRD2, Scer\RRD1" Cele\Y71H2AM.20 Xtro\ppp2r4 Mmus\Ptpa Hsap\PTPA "viable,planar polarity defective" FBgn0035638 Tektin-C Tektin C http://flybase.org/reports/FBgn0035638 protein_coding_gene microtubule binding ; GO:0008017 | inferred from sequence or structural similarity cilium movement involved in cell motility ; GO:0060294 | inferred from biological aspect of ancestor with PANTHER:PTN000462267 cilium assembly ; GO:0060271 | inferred from biological aspect of ancestor with PANTHER:PTN000462267 flagellated sperm motility ; GO:0030317 | inferred from biological aspect of ancestor with PANTHER:PTN000462268 microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity sperm flagellum ; GO:0036126 | inferred from biological aspect of ancestor with PANTHER:PTN000462268 microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity nucleus ; GO:0005634 | inferred from biological aspect of ancestor with PANTHER:PTN000462267 "CG10541, Tektin-C" IPR000435:Tektin CG10541 27-Aug-18 DroID_v2018_08 "Drer\tekt3, Drer\tekt2, Drer\tekt4, Drer\tekt1" Scer\SPC110 Cele\R02E12.4 "Xtro\tekt1, Xtro\tekt4, Xtro\tekt2, Xtro\tekt3" "Mmus\Tekt2, Mmus\Tekt1, Mmus\Tekt3, Mmus\Tekt5, Mmus\Tekt4" "Hsap\TEKT4, Hsap\TEKT5, Hsap\TEKT1, Hsap\TEKT2, Hsap\TEKT3" "lethal - all die before end of pupal stage,some die during pupal stage" DRSC09741 EK -0.80103823 -0.161306532 1.067311886 -3.731354252 1.74754327 0.915708564 FBgn0262524 ver verrocchio http://flybase.org/reports/FBgn0262524 protein_coding_gene single-stranded telomeric DNA binding ; GO:0043047 | contributes_to inferred from direct assay "telomere capping ; GO:0016233 | inferred from mutant phenotype telomere maintenance ; GO:0000723 | inferred from mutant phenotype neurogenesis ; GO:0022008 | inferred from mutant phenotype telomere capping ; GO:0016233 | inferred by curator from GO:0000782,GO:0043047" "telomere cap complex ; GO:0000782 | inferred from direct assay polytene chromosome, telomeric region ; GO:0035012 | inferred from direct assay" "ver, CG14121, 1479/10, anon-WO0172774.89, anon-WO0172774.87, anon-WO0172774.86, l(3)S147910, Ver" - CG14121 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035484 CG11594 - http://flybase.org/reports/FBgn0035484 protein_coding_gene "phosphotransferase activity, alcohol group as acceptor ; GO:0016773 | inferred from electronic annotation with InterPro:IPR000577, InterPro:IPR006003, InterPro:IPR018484, InterPro:IPR018485" "carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR000577, InterPro:IPR006003, InterPro:IPR018484, InterPro:IPR018485 response to endoplasmic reticulum stress ; GO:0034976 | inferred from mutant phenotype" - CG11594 "IPR006003:FGGY carbohydrate kinase, pentulose kinase, IPR018485:Carbohydrate kinase, FGGY, C-terminal, IPR018484:Carbohydrate kinase, FGGY, N-terminal, IPR000577:Carbohydrate kinase, FGGY" CG11594 27-Aug-18 DroID_v2018_08 Drer\fggy "Scer\YDR109C, Scer\MPA43" - Xtro\fggy Mmus\Fggy Hsap\FGGY viable FBgn0030519 CG11151 - http://flybase.org/reports/FBgn0030519 protein_coding_gene - - lipid particle ; GO:0005811 | inferred from direct assay peroxisome ; GO:0005777 | inferred from sequence model peroxisome ; GO:0005777 | inferred from biological aspect of ancestor with PANTHER:PTN000009767 "2, CG11151" IPR003033:SCP2 sterol-binding domain CG11151 27-Aug-18 DroID_v2018_08 "Drer\scp2b, Drer\hsd17b4" Scer\FOX2 "Cele\dhrs-4, Cele\maoc-1, Cele\nlt-1, Cele\dhs-28" Xtro\hsd17b4 "Mmus\Hsd17b4, Mmus\Scp2d1" "Hsap\SCP2D1, Hsap\HSD17B4" "visible,partially lethal - majority die,some die during pupal stage" "trichogen cell,mesothoracic tergum" DRSC19387 I 2.264954329 -0.438673305 -0.114434953 0.435375769 -1.119534833 0.781024737 FBgn0005678 mcd1 muscle cell death 1 http://flybase.org/reports/FBgn0005678 - gene - - - "mcd-1, mcd1" - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,lethal - all die before end of embryonic stage,maternal effect,some die during embryonic stage" "muscle 18a,maternal effect,muscle 18b" FBgn0013521 l(1)x lethal (1) x http://flybase.org/reports/FBgn0013521 - gene - - - "l(x), l(1)x" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0065756 l(2)SH0488 lethal (2) SH0488 http://flybase.org/reports/FBgn0065756 gene - - - "l(2)SH0488, l(2)SH2 0488" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0022367 Pt-6 Larval protein-6 http://flybase.org/reports/FBgn0022367 - gene - - - Pt-6 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260287 GSd451 - http://flybase.org/reports/FBgn0260287 gene - - - GSd451 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0034664 CG4377 - http://flybase.org/reports/FBgn0034664 protein_coding_gene - - - "CT14296, CG4377" IPR008472:Domain of unknown function DUF753 CG4377 27-Aug-18 DroID_v2018_08 - - "Cele\F55B11.4, Cele\D1081.6, Cele\C54D10.13, Cele\ZK757.10" - "Mmus\Ly6d, Mmus\Lynx1, Mmus\Slurp2, Mmus\2010109I03Rik" "Hsap\LYNX1, Hsap\LY6D" viable FBgn0023066 l(1)20BFa lethal (1) 20BFa http://flybase.org/reports/FBgn0023066 - gene - - - "400C20a, l(1)20BFa" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0013268 Eip4F Eip4F http://flybase.org/reports/FBgn0013268 - gene - - - "4F, Eip4F" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060773 l(3)S061308 lethal (3) S061308 http://flybase.org/reports/FBgn0060773 gene - - - "0613/08, l(3)S061308" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive,lethal - all die before end of pupal stage,some die during pupal stage,lethal" FBgn0040707 CG15430 - http://flybase.org/reports/FBgn0040707 protein_coding_gene - - - CG15430 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034052 CG8299 - http://flybase.org/reports/FBgn0034052 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 serine-type endopeptidase activity ; GO:0004252 | inferred from sequence model "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114 proteolysis ; GO:0006508 | inferred from sequence model" cytoplasm ; GO:0005737 | inferred from biological aspect of ancestor with PANTHER:PTN001208729 "SP65, CG8299" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site, IPR033116:Serine proteases, trypsin family, serine active site" CG8299 27-Aug-18 DroID_v2018_08 "Drer\LOC560023, Drer\zmp:0000001088, Drer\si:dkey-33m11.8" - "Cele\try-1, Cele\svh-1" - "Mmus\Prss47, Mmus\Prss36, Mmus\Prss53" "Hsap\PRSS36, Hsap\PRSS53" viable FBgn0259297 EP-232 - http://flybase.org/reports/FBgn0259297 gene - - - EP-232 - - 27-Aug-18 DroID_v2018_08 - - - - - - visible "wing vein,wing" FBgn0015481 l(2)45Cb lethal (2) 45Cb http://flybase.org/reports/FBgn0015481 - gene - - - l(2)45Cb - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal FBgn0030486 Set2 SET domain containing 2 http://flybase.org/reports/FBgn0030486 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR017956 histone-lysine N-methyltransferase activity ; GO:0018024 | inferred from sequence or structural similarity with UniProtKB:Q9BZ95 histone methyltransferase activity (H3-K36 specific) ; GO:0046975 | inferred from mutant phenotype phosphoprotein binding ; GO:0051219 | inferred from physical interaction with RpII215 "regulation of transcription, DNA-templated ; GO:0006355 | inferred from electronic annotation with InterPro:IPR013257 histone methylation ; GO:0016571 | inferred from sequence or structural similarity with UniProtKB:Q9BZ95 instar larval development ; GO:0002168 | inferred from mutant phenotype wing disc development ; GO:0035220 | inferred from mutant phenotype ecdysone receptor-mediated signaling pathway ; GO:0035076 | inferred from genetic interaction with EcR histone H3-K36 methylation ; GO:0010452 | inferred from mutant phenotype" chromosome ; GO:0005694 | inferred from electronic annotation with InterPro:IPR013257 nucleus ; GO:0005634 | inferred from direct assay "SET2, Set2, CG1716, dSet2, set2, Hypb, dHypb" "IPR001202:WW domain, IPR001214:SET domain, IPR003616:Post-SET domain, IPR006560:AWS domain, IPR017956:AT hook, DNA-binding motif, IPR013257:SRI, Set2 Rpb1 interacting" CG1716 27-Aug-18 DroID_v2018_08 "Drer\phf3, Drer\setd2, Drer\nsd1b, Drer\whsc1, Drer\ash1l, Drer\whsc1l1, Drer\phf20l1, Drer\phf20b, Drer\kmt2d, Drer\kmt2e, Drer\setd1ba" "Scer\BYE1, Scer\SET3, Scer\SET1, Scer\SET4, Scer\CTI6, Scer\SET2" "Cele\set-19, Cele\mes-4, Cele\set-26, Cele\set-9, Cele\C16A11.4, Cele\set-5, Cele\set-20, Cele\lin-59, Cele\set-12, Cele\set-16, Cele\met-1" "Xtro\setd2, Xtro\setd1b" "Mmus\Whsc1l1, Mmus\Phf3, Mmus\Setd1a, Mmus\Ash1l, Mmus\Phf20l1, Mmus\Kmt2c, Mmus\Kmt2d, Mmus\Setd2, Mmus\Whsc1, Mmus\Setd5, Mmus\Nsd1, Mmus\Dido1, Mmus\Spocd1, Mmus\Kmt2e, Mmus\Setd1b" "Hsap\KMT2D, Hsap\KMT2E, Hsap\SETD5, Hsap\WHSC1, Hsap\DIDO1, Hsap\ASH1L, Hsap\PHF20L1, Hsap\SETD1B, Hsap\KMT2C, Hsap\SETD1A, Hsap\NSD1, Hsap\PHF20, Hsap\SETD2, Hsap\WHSC1L1" "visible,developmental rate defective,lethal - all die before end of larval stage,some die during third instar larval stage,viable,recessive,somatic clone" "wing,eye,somatic clone" FBgn0052462 CG32462 - http://flybase.org/reports/FBgn0052462 protein_coding_gene - - - "CG8220, CG32462" - CG32462 27-Aug-18 DroID_v2018_08 - - - - - - "viable,fertile,partially lethal - majority die,some die during pupal stage" FBgn0036207 CG10907 - http://flybase.org/reports/FBgn0036207 protein_coding_gene "peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from electronic annotation with InterPro:IPR002130, InterPro:IPR020892, InterPro:IPR024936" "protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR002130, InterPro:IPR020892, InterPro:IPR024936 protein peptidyl-prolyl isomerization ; GO:0000413 | inferred from electronic annotation with InterPro:IPR002130 mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011,GO:0071013" precatalytic spliceosome ; GO:0071011 | inferred from direct assay catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay CG10907 "IPR002130:Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain, IPR024936:Cyclophilin-type peptidyl-prolyl cis-trans isomerase, IPR029000:Cyclophilin-like domain, IPR020892:Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site" CG10907 27-Aug-18 DroID_v2018_08 Drer\cwc27 "Scer\CPR2, Scer\CWC27, Scer\CPR5" Cele\cyn-16 Xtro\cwc27 Mmus\Cwc27 Hsap\CWC27 viable FBgn0054038 CG34038 - http://flybase.org/reports/FBgn0054038 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "BP1023, CG34038, Dm_2R:93795, Dm_2R:93799" IPR031941:Domain of unknown function DUF4773 CG34038 27-Aug-18 DroID_v2018_08 - - Cele\C09D4.2 - - - FBgn0019984 Gp14B Glycoprotein 14B http://flybase.org/reports/FBgn0019984 - gene - - - "gp, Gp14B" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262458 mir-305 mir-305 stem loop http://flybase.org/reports/FBgn0262458 miRNA_gene - response to starvation ; GO:0042594 | inferred from mutant phenotype intestinal stem cell homeostasis ; GO:0036335 | inferred from mutant phenotype cellular response to nutrient ; GO:0031670 | inferred from mutant phenotype regulation of insulin receptor signaling pathway ; GO:0046626 | inferred from direct assay regulation of Notch signaling pathway ; GO:0008593 | inferred from direct assay - "mir-305, 305, dme-mir-305, miR-305, MIR-305, CR43032, CR33608, mir305, miR 305, miR305, MiR-305, dme-miR-305, miR-305-5p" - CR43032 27-Aug-18 DroID_v2018_08 - - - - - - "visible,lethal" wing FBgn0000423 ddl displaced-like http://flybase.org/reports/FBgn0000423 - gene - - - "dd[3], ddl" - - 27-Aug-18 DroID_v2018_08 - - - - - - "visible,viable,reduced,male sterile,male,poor" "adult head,eye,macrochaeta & adult thorax,wing" FBgn0035157 CG13894 - http://flybase.org/reports/FBgn0035157 protein_coding_gene DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR009057 - - "dmCG13894, CG13894" "IPR006600:HTH CenpB-type DNA-binding domain, IPR006612:Zinc finger, C2CH-type, IPR009057:Homeobox domain-like, IPR015943:WD40/YVTN repeat-like-containing domain" CG13894 27-Aug-18 DroID_v2018_08 Drer\si:dkey-20i10.7 - - - Mmus\Thap11 - viable FBgn0040642 CG12545 - http://flybase.org/reports/FBgn0040642 protein_coding_gene - - - CG12545 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0084765 1577 1577 http://flybase.org/reports/FBgn0084765 gene - - - 1577 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0014918 anon-72ABb anon-72ABb http://flybase.org/reports/FBgn0014918 - gene - - - anon-72ABb - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0085267 CG34238 - http://flybase.org/reports/FBgn0085267 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG34238 - CG34238 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0028878 CG15269 - http://flybase.org/reports/FBgn0028878 protein_coding_gene nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 - - "BG:DS04929.3, DS04929.3, CG15269" "IPR013087:Zinc finger C2H2-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG15269 27-Aug-18 DroID_v2018_08 "Drer\plagl2, Drer\plagx, Drer\zbtb41" Scer\AZF1 "Cele\Y48G8AL.10, Cele\blmp-1, Cele\Y55F3AM.14, Cele\M03D4.4, Cele\sdz-12, Cele\fezf-1, Cele\Y5F2A.4, Cele\row-1" Xtro\plag1 "Mmus\Plag1, Mmus\Plagl2, Mmus\Zfp273, Mmus\Zscan10, Mmus\Plagl1, Mmus\Zfp13, Mmus\Zfp276, Mmus\Zfp629, Mmus\Zfp384, Mmus\Zfp362" "Hsap\ZNF629, Hsap\ZNF613, Hsap\ZNF628, Hsap\ZNF652, Hsap\ZNF667, Hsap\ZNF232, Hsap\ZNF621, Hsap\ZNF276, Hsap\PLAGL2, Hsap\PLAGL1, Hsap\PLAG1, Hsap\PRDM16, Hsap\ZNF205" viable FBgn0034009 CG8155 - http://flybase.org/reports/FBgn0034009 protein_coding_gene GTPase activator activity ; GO:0005096 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with Evi5 Rab GTPase binding ; GO:0017137 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 regulation of GTPase activity ; GO:0043087 | inferred from sequence or structural similarity with Evi5 activation of GTPase activity ; GO:0090630 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 intracellular protein transport ; GO:0006886 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 regulation of vesicle fusion ; GO:0031338 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype border follicle cell migration ; GO:0007298 | inferred from mutant phenotype autophagosome ; GO:0005776 | inferred from biological aspect of ancestor with PANTHER:PTN000538498 endomembrane system ; GO:0012505 | inferred from biological aspect of ancestor with PANTHER:PTN000537561 CG8155 IPR000195:Rab-GTPase-TBC domain CG8155 27-Aug-18 DroID_v2018_08 "Drer\tbc1d15, Drer\tbc1d17, Drer\tbc1d25, Drer\si:dkey-238d18.4" Scer\GYP7 - - "Mmus\Tbc1d25, Mmus\Tbc1d15, Mmus\Tbc1d21, Mmus\Tbc1d17" "Hsap\TBC1D21, Hsap\TBC1D15, Hsap\TBC1D17, Hsap\TBC1D25" "long lived,visible,partially lethal - majority die,some die during pupal stage,cell migration defective" "trichogen cell,mesothoracic tergum,border follicle cell" FBgn0033635 Prip Prip http://flybase.org/reports/FBgn0033635 protein_coding_gene channel activity ; GO:0015267 | inferred from sequence or structural similarity with Drip water channel activity ; GO:0015250 | inferred from biological aspect of ancestor with PANTHER:PTN000440615 transmembrane transport ; GO:0055085 | inferred from sequence or structural similarity with Drip ion transmembrane transport ; GO:0034220 | inferred from biological aspect of ancestor with PANTHER:PTN000440615 integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with Drip integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000440615 "CG7777, Aqp7777, Prip" "IPR000425:Major intrinsic protein, IPR034294:Aquaporin transporter, IPR023271:Aquaporin-like" CG7777 27-Aug-18 DroID_v2018_08 "Drer\aqp1a.1, Drer\aqp8a.2, Drer\aqp3b, Drer\mipa, Drer\aqp1a.2, Drer\aqp8b, Drer\aqp4, Drer\aqp3a, Drer\mipb, Drer\si:dkey-30h22.11, Drer\aqp8a.1" "Scer\AQY2, Scer\YLL053C, Scer\YFL054C, Scer\AQY1" "Cele\aqp-4, Cele\aqp-7, Cele\aqp-6, Cele\aqp-2, Cele\aqp-8, Cele\aqp-5" "Xtro\mip, Xtro\LOC100216133, Xtro\aqp2, Xtro\fam188b, Xtro\aqp5, Xtro\LOC100489792, Xtro\aqp1, Xtro\aqp8" "Mmus\Aqp1, Mmus\Aqp2, Mmus\Aqp4, Mmus\Aqp3, Mmus\Aqp8, Mmus\Aqp5, Mmus\Aqp6, Mmus\Mip, Mmus\Aqp7, Mmus\Fam188b" "Hsap\MIP, Hsap\FAM188B2, Hsap\AQP3, Hsap\AQP6, Hsap\AQP5, Hsap\AQP7, Hsap\AQP9, Hsap\AQP1, Hsap\AQP4, Hsap\AQP8, Hsap\AQP2" viable FBgn0063393 sip sine prole http://flybase.org/reports/FBgn0063393 gene - cystoblast division ; GO:0007282 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype oogenesis ; GO:0048477 | inferred from mutant phenotype - sip - - 27-Aug-18 DroID_v2018_08 - - - - - - "female sterile,recessive" "spermatozoon,spermatid,egg chamber,nurse cell,ovary,follicle cell" FBgn0265548 lncRNA:CR44398 - http://flybase.org/reports/FBgn0265548 non_protein_coding_gene - - - "CR44398, lincRNA.176" - CR44398 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0267549 asRNA:CR45889 - http://flybase.org/reports/FBgn0267549 non_protein_coding_gene - - - CR45889 - CR45889 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0027836 Dgp-1 Dgp-1 http://flybase.org/reports/FBgn0027836 - protein_coding_gene GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR000795 GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR000795 molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG5729, Dgp-1" "IPR000795:Transcription factor, GTP-binding domain, IPR009000:Translation protein, beta-barrel domain, IPR009001:Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal, IPR027417:P-loop containing nucleoside triphosphate hydrolase" CG5729 27-Aug-18 DroID_v2018_08 "Drer\gtpbp1l, Drer\gtpbp2, Drer\gtpbp1" - "Cele\cgp-1, Cele\T04H1.2" "Xtro\gtpbp1, Xtro\gtpbp2" "Mmus\Gtpbp1, Mmus\Gtpbp2" "Hsap\GTPBP2, Hsap\GTPBP1" "viable,fertile,body color defective" mesothoracic tergum FBgn0027496 epsilonCOP Coat Protein (coatomer) epsilon http://flybase.org/reports/FBgn0027496 - protein_coding_gene structural molecule activity ; GO:0005198 | inferred from electronic annotation with InterPro:IPR006822 "ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from biological aspect of ancestor with PANTHER:PTN000086687 retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | inferred from biological aspect of ancestor with PANTHER:PTN000086687 intra-Golgi vesicle-mediated transport ; GO:0006891 | inferred from biological aspect of ancestor with PANTHER:PTN000086687" COPI vesicle coat ; GO:0030126 | inferred from direct assay microtubule associated complex ; GO:0005875 | inferred from direct assay "BcDNA:LD29885, CG9543, epsilonCOP, bcDNA:LD29885, epsilon-COP, epsilon-Cop" "IPR006822:Coatomer, epsilon subunit, IPR011990:Tetratricopeptide-like helical domain" CG9543 27-Aug-18 DroID_v2018_08 Drer\cope Scer\SEC28 Cele\cope-1 Xtro\cope Mmus\Cope Hsap\COPE viable FBgn0002858 Mst51F Male-specific RNA 51F http://flybase.org/reports/FBgn0002858 - gene - - - "mst-35, mst(2)ag-35, Mst51F" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0025004 E(var)3-101 E(var)3-101 http://flybase.org/reports/FBgn0025004 - gene - - - "E-(3)1[01], E(var)3-101" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0031990 PAPLA1 Phosphatidic Acid Phospholipase A1 http://flybase.org/reports/FBgn0031990 protein_coding_gene metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR004177 phospholipase activity ; GO:0004620 | inferred from mutant phenotype rhodopsin biosynthetic process ; GO:0016063 | inferred from mutant phenotype ER to Golgi vesicle-mediated transport ; GO:0006888 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype ER to Golgi transport vesicle ; GO:0030134 | inferred from direct assay nucleoplasm ; GO:0005654 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG14278, CG8552, Sec23-IP, PAPLA1" "IPR004170:WWE domain, IPR004177:DDHD domain, IPR029058:Alpha/Beta hydrolase fold" CG8552 27-Aug-18 DroID_v2018_08 "Drer\sec23ip, Drer\ddhd2, Drer\ddhd1a, Drer\ddhd1b" "Scer\YOR022C, Scer\FIG2" "Cele\lec-2, Cele\ipla-1" "Xtro\ddhd2, Xtro\sec23ip" "Mmus\Ddhd1, Mmus\Ddhd2, Mmus\Sec23ip" "Hsap\SEC23IP, Hsap\DDHD1, Hsap\DDHD2" "viable,fertile" FBgn0084797 G56 G56 http://flybase.org/reports/FBgn0084797 gene - - - G56 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0062636 EP995 EP995 http://flybase.org/reports/FBgn0062636 gene - - - "EP(3)0995, EP995" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260431 CG42526 - http://flybase.org/reports/FBgn0260431 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG42526 IPR006578:MADF domain CG42526 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-207i20.3, Drer\LOC100330838, Drer\zgc:152938" - "Cele\madf-8, Cele\madf-10, Cele\madf-2, Cele\madf-3, Cele\madf-9, Cele\madf-4, Cele\madf-5" - - - FBgn0032213 CG5390 - http://flybase.org/reports/FBgn0032213 protein_coding_gene serine-type endopeptidase activity ; GO:0004252 | NOT inferred from key residues "proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114" extracellular region ; GO:0005576 | inferred from direct assay "CG5390, c-SPH35, SPH35, gh06341, BEST:GH06341, SPH" "IPR001254:Serine proteases, trypsin domain, IPR001314:Peptidase S1A, chymotrypsin family, IPR009003:Peptidase S1, PA clan, IPR018114:Serine proteases, trypsin family, histidine active site" CG5390 27-Aug-18 DroID_v2018_08 "Drer\masp2, Drer\f7" - Cele\try-1 - "Mmus\Klkb1, Mmus\Klk1b5, Mmus\Klk1b11, Mmus\F11, Mmus\Klk1b3, Mmus\Klk1b22, Mmus\Klk1b1, Mmus\Klk1b9, Mmus\Klk1b8, Mmus\Klk11, Mmus\Klk1, Mmus\Klk1b21, Mmus\Klk1b16, Mmus\Klk1b27, Mmus\Egfbp2, Mmus\Klk1b4, Mmus\Klk1b24, Mmus\Klk1b26" "Hsap\KLK11, Hsap\KLK3, Hsap\KLK2, Hsap\F11, Hsap\KLKB1, Hsap\KLK1" viable FBgn0266157 lncRNA:CR44863 - http://flybase.org/reports/FBgn0266157 non_protein_coding_gene - - - CR44863 - CR44863 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0023508 Ocrl Oculocerebrorenal syndrome of Lowe http://flybase.org/reports/FBgn0023508 - protein_coding_gene phosphatidylinositol bisphosphate phosphatase activity ; GO:0034593 | inferred from mutant phenotype GTPase activator activity ; GO:0005096 | NOT inferred from key residues GTPase activator activity ; GO:0005096 | inferred from sequence or structural similarity with HGNC:8108 "signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR000198, InterPro:IPR008936 mitotic cytokinesis ; GO:0000281 | inferred from mutant phenotype actomyosin contractile ring localization ; GO:0032187 | inferred from mutant phenotype regulation of GTPase activity ; GO:0043087 | inferred from sequence or structural similarity with HGNC:8108 phosphatidylinositol dephosphorylation ; GO:0046856 | inferred from mutant phenotype regulation of cytokinesis, actomyosin contractile ring assembly ; GO:2000431 | inferred from mutant phenotype endocytosis ; GO:0006897 | inferred from mutant phenotype" early endosome ; GO:0005769 | inferred from direct assay recycling endosome ; GO:0055037 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay late endosome ; GO:0005770 | inferred from direct assay "EG:86E4.5, CG3573, ocrl, Ocrl, dOCRL" "IPR000198:Rho GTPase-activating protein domain, IPR000300:Inositol polyphosphate-related phosphatase, IPR005135:Endonuclease/exonuclease/phosphatase, IPR008936:Rho GTPase activation protein, IPR013783:Immunoglobulin-like fold, IPR031896:Type II inositol 1,4,5-trisphosphate 5-phosphatase, PH domain" CG3573 27-Aug-18 DroID_v2018_08 "Drer\inpp5jb, Drer\inpp5ka, Drer\inpp5b, Drer\inpp5kb, Drer\sh2d1aa, Drer\ocrl, Drer\inppl1b, Drer\inpp5d, Drer\inpp5e, Drer\inpp5j, Drer\inppl1a" "Scer\INP52, Scer\INP54, Scer\INP51, Scer\INP53" Cele\ocrl-1 "Xtro\inpp5k, Xtro\inpp5b, Xtro\inpp5d, Xtro\sec16a, Xtro\ocrl, Xtro\inpp5j" "Mmus\Inpp5e, Mmus\Inpp5d, Mmus\Sh2d1b2, Mmus\Inpp5k, Mmus\Inpp5b, Mmus\Ocrl, Mmus\Inpp5j, Mmus\Inppl1, Mmus\Sh2d1b1, Mmus\Sh2d1a" "Hsap\INPP5D, Hsap\OCRL, Hsap\SH2D1B, Hsap\INPP5J, Hsap\INPP5B, Hsap\INPP5E, Hsap\INPP5K, Hsap\INPPL1" "viable,fertile,visible" "chaeta,supernumerary" FBgn0261956 baz::par-6 - http://flybase.org/reports/FBgn0261956 engineered_fusion_gene - - - baz::par-6 - - 27-Aug-18 DroID_v2018_08 - - - - - - lethal "follicle cell,somatic clone" FBgn0045852 ham hamlet http://flybase.org/reports/FBgn0045852 protein_coding_gene "nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087 transcription factor activity, sequence-specific DNA binding ; GO:0003700 | inferred from mutant phenotype" "dendrite morphogenesis ; GO:0048813 | traceable author statement neuroblast fate commitment ; GO:0014017 | inferred from mutant phenotype regulation of dendrite development ; GO:0050773 | inferred from mutant phenotype negative regulation of cell proliferation ; GO:0008285 | inferred from mutant phenotype regulation of transcription, DNA-templated ; GO:0006355 | inferred from mutant phenotype neuron development ; GO:0048666 | inferred from mutant phenotype" nucleus ; GO:0005634 | traceable author statement nucleus ; GO:0005634 | inferred from direct assay "CG15906, CG10568, CG31753, CG15907, ham, Ham, HAM_DROME, hamlet" "IPR013087:Zinc finger C2H2-type, IPR030413:Evi1/Prdm16, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG31753 27-Aug-18 DroID_v2018_08 "Drer\mecom, Drer\znf1010, Drer\znf1015, Drer\si:ch211-263k4.2, Drer\znf1004" "Scer\MSN2, Scer\MSN4, Scer\COM2" "Cele\zag-1, Cele\egl-43" "Xtro\klf17, Xtro\znf850, Xtro\znf180" "Mmus\Zfp442, Mmus\Prdm16, Mmus\AU041133, Mmus\Zfp617, Mmus\Zfp729a, Mmus\Zfp27, Mmus\Zfp62, Mmus\Zfp316, Mmus\Gli1, Mmus\Zfp26, Mmus\Zfp112, Mmus\Klf11, Mmus\Klf10, Mmus\Mecom, Mmus\Zfp619, Mmus\Zfp808, Mmus\Zfp236" "Hsap\ZNF85, Hsap\ZNF605, Hsap\ZNF808, Hsap\ZFP62, Hsap\ZNF721, Hsap\ZNF107, Hsap\ZNF883, Hsap\MECOM, Hsap\ZNF160, Hsap\ZNF91, Hsap\ZNF260, Hsap\PRDM16, Hsap\ZNF99, Hsap\ZNF211, Hsap\ZNF628, Hsap\ZNF208, Hsap\ZNF850, Hsap\ZNF676, Hsap\ZNF624, Hsap\ZNF587, Hsap\ZNF841, Hsap\ZNF836, Hsap\ZNF347, Hsap\ZNF696, Hsap\ZNF236, Hsap\KLF10, Hsap\ZNF780B, Hsap\ZNF658, Hsap\ZNF729" "viable,neuroanatomy defective,visible,decreased cell number,decreased cell size" "multidendritic neuron,supernumerary,dorsal abdominal cluster,eo neuron,trichogen cell,ectopic,tormogen cell,somatic clone,embryonic/larval nervous system,abdominal ventral sensillum campaniformium vc4a,secondary neuroblast,chaeta,type II neuroblast,type I neuroblast,ganglion mother cell" DRSC02070 K 0.544462478 0.908231016 -0.347781259 0.546755864 1.575814222 0.329884486 FBgn0039238 CG7016 - http://flybase.org/reports/FBgn0039238 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG7016 - CG7016 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible" mesothoracic tergum FBgn0082351 HM385 HM385 http://flybase.org/reports/FBgn0082351 gene - - - HM385 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262685 CG43155 - http://flybase.org/reports/FBgn0262685 protein_coding_gene "potassium channel activity ; GO:0005267 | inferred from sequence or structural similarity with Task7, Task6" "potassium ion transmembrane transport ; GO:0071805 | inferred from sequence or structural similarity with Task7, Task6" "integral component of membrane ; GO:0016021 | inferred from sequence or structural similarity with Task7, Task6" "CG43155, CG1756, CG15194, anon-WO0109301.9, anon-WO0109301.52, anon-WO0109301.51" "IPR003280:Two pore domain potassium channel, IPR013099:Potassium channel domain" CG43155 27-Aug-18 DroID_v2018_08 "Drer\kcnk6, Drer\kcnk18, Drer\kcnk1b, Drer\kcnk10a, Drer\kcnk3a, Drer\kcnk7, Drer\kcnk10b, Drer\kcnk1a, Drer\kcnk15, Drer\kcnk2a, Drer\kcnk5a, Drer\kcnk9, Drer\kcnk5b, Drer\kcnk3b" "Scer\CTF3, Scer\TOK1" "Cele\twk-30, Cele\twk-3, Cele\twk-23, Cele\twk-46, Cele\twk-47, Cele\unc-58, Cele\twk-28, Cele\twk-32, Cele\twk-17, Cele\twk-7, Cele\twk-43, Cele\twk-2, Cele\twk-5, Cele\twk-29, Cele\twk-16, Cele\twk-10, Cele\egl-23, Cele\twk-20, Cele\twk-13, Cele\twk-37, Cele\sup-9, Cele\twk-4, Cele\twk-9, Cele\twk-40" "Xtro\kcnk18, Xtro\kcnk16, Xtro\LOC100486031, Xtro\kcnk7, Xtro\kcnk1, Xtro\kcnk6, Xtro\kcnk2, Xtro\kcnk4, Xtro\kcnk10, Xtro\kcnk5" "Mmus\Kcnk9, Mmus\Kcnk1, Mmus\Kcnk2, Mmus\Kcnk10, Mmus\Kcnk16, Mmus\Kcnk7, Mmus\Kcnk3, Mmus\Kcnk18, Mmus\Kcnk4, Mmus\Kcnk5, Mmus\Kcnk15, Mmus\Kcnk6" "Hsap\KCNK15, Hsap\KCNK2, Hsap\KCNK5, Hsap\KCNK9, Hsap\KCNK1, Hsap\BCL2, Hsap\KCNK6, Hsap\KCNK7, Hsap\KCNK17, Hsap\KCNK16, Hsap\KCNK3, Hsap\KCNK4, Hsap\KCNK10, Hsap\KCNK18" DRSC19777 K 0.856439848 0.672049348 -0.083395298 0.06439373 0.615555262 -1.797781903 FBgn0084019 CG41457 - http://flybase.org/reports/FBgn0084019 protein_coding_gene - - - CG41457 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0036602 CG13042 - http://flybase.org/reports/FBgn0036602 protein_coding_gene - - - CG13042 IPR007614:Retinin-like protein CG13042 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0011815 mei-269 mei-269 http://flybase.org/reports/FBgn0011815 - gene - - - mei-269 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0060386 l(3)S134306a lethal (3) S134306a http://flybase.org/reports/FBgn0060386 gene - - - "1343/06, l(3)S134306a" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0027608 CG2082 - http://flybase.org/reports/FBgn0027608 - protein_coding_gene - - - "BcDNA:GH02439, CG2082" "IPR004142:NDRG, IPR029058:Alpha/Beta hydrolase fold" CG2082 27-Aug-18 DroID_v2018_08 "Drer\ndrg1a, Drer\ndrg2, Drer\ndrg4, Drer\ndrg3a, Drer\ndrg3b, Drer\ndrg1b" - "Cele\ZK1073.1, Cele\Y48G10A.3" "Xtro\ndrg2, Xtro\ndrg3, Xtro\ndrg1, Xtro\ndrg4" "Mmus\Ndrg4, Mmus\Ndrg2, Mmus\Ndrg3, Mmus\Ndrg1" "Hsap\NDRG4, Hsap\NDRG1, Hsap\NDRG3, Hsap\NDRG2" "viable,fertile,partially lethal - majority die" DRSC12125 E 0.014805064 0.822488474 3.187014626 0.687041031 -0.885840314 -0.544545221 FBgn0024224 ird10 immune response deficient 10 http://flybase.org/reports/FBgn0024224 - gene - positive regulation of antibacterial peptide biosynthetic process ; GO:0006963 | inferred from mutant phenotype - "ird, ird10" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0033735 CG8525 - http://flybase.org/reports/FBgn0033735 protein_coding_gene deoxyribose-phosphate aldolase activity ; GO:0004139 | inferred from biological aspect of ancestor with PANTHER:PTN000095292 carbohydrate catabolic process ; GO:0016052 | inferred from biological aspect of ancestor with PANTHER:PTN000095292 deoxyribonucleotide catabolic process ; GO:0009264 | inferred from biological aspect of ancestor with PANTHER:PTN000095292 cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR011343 CG8525 "IPR002915:DeoC/FbaB/ lacD aldolase, IPR011343:Deoxyribose-phosphate aldolase, IPR013785:Aldolase-type TIM barrel" CG8525 27-Aug-18 DroID_v2018_08 Drer\dera - Cele\F09E5.3 Xtro\dera Mmus\Dera Hsap\DERA "viable,fertile" FBgn0250820 meigo medial glomeruli http://flybase.org/reports/FBgn0250820 protein_coding_gene UDP-galactose transmembrane transporter activity ; GO:0005459 | inferred from biological aspect of ancestor with PANTHER:PTN000081293 dendrite guidance ; GO:0070983 | inferred from mutant phenotype UDP-galactose transmembrane transport ; GO:0072334 | inferred from biological aspect of ancestor with PANTHER:PTN000081293 axon guidance ; GO:0007411 | inferred from mutant phenotype response to endoplasmic reticulum stress ; GO:0034976 | inferred from mutant phenotype inferred from genetic interaction with Hsc70-3 protein N-linked glycosylation ; GO:0006487 | inferred from mutant phenotype endoplasmic reticulum membrane ; GO:0005789 | inferred from direct assay integral component of endoplasmic reticulum membrane ; GO:0030176 | inferred from biological aspect of ancestor with PANTHER:PTN000081292 integral component of Golgi membrane ; GO:0030173 | inferred from biological aspect of ancestor with PANTHER:PTN000081292 "anon-EST:fe1H6, NEST:bs03h03, CG5802, meigo, Meigo" IPR013657:UAA transporter CG5802 27-Aug-18 DroID_v2018_08 "Drer\slc35b1, Drer\slc35b2" Scer\HUT1 "Cele\hut-1, Cele\pst-1" Xtro\slc35b1 "Mmus\Slc35b1, Mmus\Slc35b2" "Hsap\SLC35B1, Hsap\SLC35B2" FBgn0037320 CG14668 - http://flybase.org/reports/FBgn0037320 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available CG14668 - CG14668 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0062524 l(3)88EFh lethal (3) 88EFh http://flybase.org/reports/FBgn0062524 gene - - - l(3)88EFh - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of embryonic stage,some die during embryonic stage" "embryonic head,abdominal 8 ventral denticle belt" FBgn0066366 dru drujok http://flybase.org/reports/FBgn0066366 gene molecular_function ; GO:0003674 | no biological data available learning or memory ; GO:0007611 | inferred from mutant phenotype olfactory learning ; GO:0008355 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available dru - - 27-Aug-18 DroID_v2018_08 - - - - - - memory defective FBgn0065699 l(2)SH0624 lethal (2) SH0624 http://flybase.org/reports/FBgn0065699 gene - - - "l(2)SH0624, l(2)SH2 0624" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0065649 l(2)SH0735 lethal (2) SH0735 http://flybase.org/reports/FBgn0065649 gene - - - "l(2)SH0735, l(2)SH2 0735" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0025463 Bap60 Brahma associated protein 60kD http://flybase.org/reports/FBgn0025463 - protein_coding_gene "transcription coactivator activity ; GO:0003713 | inferred from mutant phenotype contributes_to DNA binding ; GO:0003677 | inferred from direct assay transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ; GO:0001077 | contributes_to inferred from mutant phenotype myosin binding ; GO:0017022 | inferred from physical interaction with Myo10A transcription coactivator activity ; GO:0003713 | contributes_to inferred by curator from GO:0035060 RNA polymerase II transcription factor binding ; GO:0001085 | inferred from physical interaction with sisA inferred from physical interaction with sc protein binding ; GO:0005515 | inferred from physical interaction with mor transcription factor binding ; GO:0008134 | inferred from sequence or structural similarity with HGNC:11106" "positive regulation of transcription, DNA-templated ; GO:0045893 | inferred from direct assay positive regulation of heterochromatin assembly ; GO:0031453 | inferred from mutant phenotype dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype muscle organ development ; GO:0007517 | inferred from mutant phenotype positive regulation of gene expression ; GO:0010628 | inferred from genetic interaction with brm neuron development ; GO:0048666 | inferred from mutant phenotype regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from mutant phenotype" nuclear euchromatin ; GO:0005719 | inferred from direct assay brahma complex ; GO:0035060 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay PBAF complex ; GO:0070604 | inferred from direct assay "BAP60, CG4303, i127, i133, BAPp60, Bap60, bap60, BAF60" "IPR003121:SWIB/MDM2 domain, IPR019835:SWIB domain" CG4303 27-Aug-18 DroID_v2018_08 "Drer\smarcd1, Drer\asic1b, Drer\asic2, Drer\smarcd2, Drer\smarcd3b, Drer\smarcd3a, Drer\asic1a" "Scer\TRI1, Scer\SNF12, Scer\RSC6, Scer\UAF30" "Cele\ham-3, Cele\acd-5, Cele\swsn-2.2, Cele\T24G10.2" "Xtro\smarcd2, Xtro\smarcd1, Xtro\smarcd3" "Mmus\Asic2, Mmus\Smarcd2, Mmus\Smarcd1, Mmus\Smarcd3, Mmus\Asic1" "Hsap\SMARCD1, Hsap\ASIC1, Hsap\SMARCD3, Hsap\SMARCD2, Hsap\ASIC2" "viable,lethal,recessive,germline clone,non-rescuable maternal effect,suppressor of variegation,dominant" embryonic/larval brain FBgn0261262 CG42613 - http://flybase.org/reports/FBgn0261262 protein_coding_gene molecular_function ; GO:0003674 | no biological data available sleep ; GO:0030431 | inferred from expression pattern cellular_component ; GO:0005575 | no biological data available "CG42613, CG5449, tld-like, CT33918, CT17110, CG14289, CG31149, CG31222" "IPR000859:CUB domain, IPR002172:Low-density lipoprotein (LDL) receptor class A repeat" CG42613 27-Aug-18 DroID_v2018_08 "Drer\si:ch211-233f16.1, Drer\si:cabz01033205.3" - "Cele\sol-1, Cele\sol-2, Cele\lev-10" Xtro\mfrp "Mmus\Nrp2, Mmus\Mfrp" "Hsap\MFRP, Hsap\NRP2" DRSC13332 K -0.608738434 1.4562073 -0.171171736 1.493621161 2.15543771 2.346558651 FBgn0267663 lncRNA:CR46001 - http://flybase.org/reports/FBgn0267663 non_protein_coding_gene - - - CR46001 - CR46001 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0001957 l(2)28Bc lethal (2) 28Bc http://flybase.org/reports/FBgn0001957 - gene - - - "O, l(2)28Bc" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0001686 l(1)ESHS7 lethal (1) ESHS7 http://flybase.org/reports/FBgn0001686 - gene - - - l(1)ESHS7 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0033571 Rpb5 Rpb5 http://flybase.org/reports/FBgn0033571 protein_coding_gene "DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR000783, InterPro:IPR005571, InterPro:IPR020609 RNA polymerase I activity ; GO:0001054 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000056681 RNA polymerase II activity ; GO:0001055 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000056681 DNA-directed RNA polymerase activity ; GO:0003899 | inferred from sequence or structural similarity with HGNC:9192 inferred from sequence or structural similarity with SGD:S000000358 RNA polymerase III activity ; GO:0001056 | contributes_to inferred from biological aspect of ancestor with PANTHER:PTN000056681" transcription from RNA polymerase II promoter ; GO:0006366 | inferred from sequence or structural similarity with HGNC:9192 inferred from sequence or structural similarity with SGD:S000000358 mitotic G2 DNA damage checkpoint ; GO:0007095 | inferred from genetic interaction with nbs "DNA-directed RNA polymerase II, core complex ; GO:0005665 | inferred from sequence or structural similarity with HGNC:9192 inferred from sequence or structural similarity with SGD:S000000358 DNA-directed RNA polymerase II, core complex ; GO:0005665 | inferred from biological aspect of ancestor with PANTHER:PTN000056681 DNA-directed RNA polymerase I complex ; GO:0005736 | inferred from biological aspect of ancestor with PANTHER:PTN000056681 DNA-directed RNA polymerase III complex ; GO:0005666 | inferred from biological aspect of ancestor with PANTHER:PTN000056681" "RPB5, CG11979, DmRPB5, Rpb5" "IPR000783:RNA polymerase, subunit H/Rpb5 C-terminal, IPR005571:RNA polymerase, Rpb5, N-terminal, IPR014381:DNA-directed RNA polymerase RPB5 subunit, eukaryote/virus, IPR020609:Archaeal RpoH /eukaryotic RPB5 RNA polymerase subunit, IPR020608:RNA polymerase, subunit H/Rpb5, conserved site" CG11979 27-Aug-18 DroID_v2018_08 "Drer\polr2ea, Drer\polr2eb" Scer\RPB5 Cele\rpb-5 Xtro\polr2e Mmus\Polr2e Hsap\POLR2E DRSC06100 IEK -0.798890607 1.895526195 -4.049868687 -0.928224466 1.34282151 4.602999553 FBgn0027324 l(1)G0041 lethal (1) G0041 http://flybase.org/reports/FBgn0027324 - gene - - - l(1)G0041 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,melanotic mass phenotype,recessive" melanotic mass FBgn0030536 CG11068 - http://flybase.org/reports/FBgn0030536 protein_coding_gene - - - CG11068 - CG11068 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0013668 ms(3)neo4 ms(3)neo4 http://flybase.org/reports/FBgn0013668 - gene - - - ms(3)neo4 - - 27-Aug-18 DroID_v2018_08 - - - - - - "semi-sterile,male sterile" FBgn0053099 CG33099 - http://flybase.org/reports/FBgn0053099 protein_coding_gene oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR005123 oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005123 - "CG5340, CG33099" "IPR027443:Isopenicillin N synthase-like, IPR026992:Non-haem dioxygenase N-terminal domain, IPR005123:Oxoglutarate/iron-dependent dioxygenase" CG33099 27-Aug-18 DroID_v2018_08 Drer\si:dkey-10o6.2 - - - - - viable FBgn0058363 CG40363 - http://flybase.org/reports/FBgn0058363 protein_coding_gene - - - CG40363 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0028980 tant tantalus http://flybase.org/reports/FBgn0028980 protein_coding_gene - sensory organ development ; GO:0007423 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay "CG6586, tan, tant" IPR028149:Tantalus-like CG6586 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible,fertile,recessive,partially lethal - majority die,lethal - all die before end of pupal stage,some die during pupal stage" "interocellar bristle,eye,ommatidium,interommatidial bristle,supernumerary,macrochaeta,scutellar bristle,abdominal sternite bristle,ectopic,abdominal tergite & macrochaeta,abdominal tergite & macrochaeta | ectopic,wing vein L5,postvertical bristle,wing vein,sex comb,joint,tarsal segment,wing,wing margin,macrochaeta & thorax-537.4,ocellar bristle" FBgn0086397 BG02320 - http://flybase.org/reports/FBgn0086397 gene - olfactory behavior ; GO:0042048 | inferred from mutant phenotype - BG02320 - - 27-Aug-18 DroID_v2018_08 - - - - - - "viable,smell perception defective" FBgn0051260 CG31260 - http://flybase.org/reports/FBgn0051260 protein_coding_gene - - - CG31260 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0262459 mir-34 mir-34 stem loop http://flybase.org/reports/FBgn0262459 miRNA_gene mRNA 3'-UTR binding ; GO:0003730 | inferred from direct assay negative regulation of neuron death ; GO:1901215 | inferred from mutant phenotype gene silencing by miRNA ; GO:0035195 | inferred from mutant phenotype muscle cell cellular homeostasis ; GO:0046716 | inferred from mutant phenotype - "dme-mir-34, mir-34, miR-34, 34, MIR-34, CR43033, Mir-34, CR33326, dme-miR-34, dme-miR-34-5p, miR-34-5p" - CR43033 27-Aug-18 DroID_v2018_08 - - - - - - " larval stage--prepupal stage , adult stage " "viable,lethal,long lived,short lived,gravitaxis defective,conditional,heat stress response defective,neuroanatomy defective" "wing,adult brain,conditional" FBgn0035198 CG9133 - http://flybase.org/reports/FBgn0035198 protein_coding_gene - - - "bs29f09.y1, CG32332, BEST:GH19464, BEST:GH19274, anon-WO0140519.53, anon-WO0140519.145, CG9133, AT07490" - CG9133 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0084058 l(3)82CDe lethal (3) 82CDe http://flybase.org/reports/FBgn0084058 gene - - - l(3)82CDe - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,heat sensitive" FBgn0062567 Mod(var)E646 Mod(var)E646 http://flybase.org/reports/FBgn0062567 gene molecular_function ; GO:0003674 | no biological data available chromatin silencing ; GO:0006342 | inferred from mutant phenotype chromatin silencing at centromere ; GO:0030702 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available "E646, Mod(var)E646" - - 27-Aug-18 DroID_v2018_08 - - - - - - "partially lethal - majority die,recessive,enhancer of variegation,non-enhancer of variegation,non-suppressor of variegation,dominant" FBgn0002794 ms(1)1 male sterile (1) 1 http://flybase.org/reports/FBgn0002794 - gene - - - ms(1)1 - - 27-Aug-18 DroID_v2018_08 - - - - - - "male sterile,female fertile,viable" "spermatid axoneme,spermatid" FBgn0028571 ren renegade http://flybase.org/reports/FBgn0028571 gene - - - ren - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0263945 BG00528 - http://flybase.org/reports/FBgn0263945 gene - - - BG00528 - - 27-Aug-18 DroID_v2018_08 - - - - - - "long lived,female limited,starvation stress response defective,temperature response defective,gravitaxis defective" FBgn0036660 CG13025 - http://flybase.org/reports/FBgn0036660 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841 zinc ion binding ; GO:0008270 | inferred from sequence model ubiquitin-protein transferase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC:25539 protein ubiquitination ; GO:0016567 | inferred from sequence or structural similarity with HGNC:25539 nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC:25539 CG13025 "IPR017986:WD40-repeat-containing domain, IPR015943:WD40/YVTN repeat-like-containing domain, IPR001680:WD40 repeat, IPR001841:Zinc finger, RING-type, IPR013083:Zinc finger, RING/FYVE/PHD-type" CG13025 27-Aug-18 DroID_v2018_08 Drer\rfwd3 - Cele\ZC13.1 Xtro\rfwd3 Mmus\Rfwd3 Hsap\RFWD3 "viable,fertile" FBgn0053728 snmRNA:430b snmRNA:430:CR33728 http://flybase.org/reports/FBgn0053728 non_protein_coding_gene - - - "CR33728, snmRNA:430:CR33728" - CR33728 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0063374 snoRNA:snR38:54Eb snoRNA:snR38:54Eb http://flybase.org/reports/FBgn0063374 snoRNA_gene - - - "Snr38snoRNA, CR32896, snoRNA:snR38:54Eb" - CR32896 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0039711 CG7824 - http://flybase.org/reports/FBgn0039711 protein_coding_gene - - - CG7824 IPR031961:Domain of unknown function DUF4780 CG7824 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0265452 lncRNA:CR44352 - http://flybase.org/reports/FBgn0265452 non_protein_coding_gene - - - "CR44352, lincRNA.83" - CR44352 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002420 l(3)DTS8 lethal (3) DTS8 http://flybase.org/reports/FBgn0002420 - gene - - - "DTS-8, l(3)DTS8" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,dominant,heat sensitive,lethal - all die before end of larval stage,some die during larval stage" FBgn0015987 l(2)PC4-Q lethal (2) PC4-Q http://flybase.org/reports/FBgn0015987 - gene - - - l(2)PC4-Q - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0015699 E(var)8 Enhancer of variegation 8 http://flybase.org/reports/FBgn0015699 - gene - - - E(var)8 - - 27-Aug-18 DroID_v2018_08 - - - - - - "enhancer of variegation,dominant" FBgn0035415 CG14966 - http://flybase.org/reports/FBgn0035415 protein_coding_gene - - - CG14966 IPR003746:Protein of unknown function DUF167 CG14966 27-Aug-18 DroID_v2018_08 Drer\zgc:193812 - Cele\W01A8.2 Xtro\c15orf40 Mmus\3110040N11Rik Hsap\C15orf40 viable FBgn0031878 sip2 septin interacting protein 2 http://flybase.org/reports/FBgn0031878 protein_coding_gene protein binding ; GO:0005515 | inferred from physical interaction with Sep1 inferred from physical interaction with Sep2 biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CG9188, sip2" - CG9188 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0002425 l(3)F24 lethal (3) F24 http://flybase.org/reports/FBgn0002425 - gene - - - "l(3)24, l(3)F24" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal - all die before end of larval stage,recessive,some die during larval stage" "wing,somatic clone,wing hair" FBgn0004492 DhpO Dihydropterin oxidase http://flybase.org/reports/FBgn0004492 - gene dihydropterin oxidase activity ; GO:0004154 | inferred from direct assay dihydropteridine metabolic process ; GO:0051067 | inferred from direct assay - DhpO - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0035208 CG9184 - http://flybase.org/reports/FBgn0035208 protein_coding_gene - - - CG9184 - CG9184 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC08636 E 0.879868527 1.027657362 1.746869918 1.431078397 0.604011885 -0.022614165 FBgn0267709 lncRNA:CR46042 - http://flybase.org/reports/FBgn0267709 non_protein_coding_gene - - - CR46042 - CR46042 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0052539 CG32539 - http://flybase.org/reports/FBgn0052539 protein_coding_gene - - - CG32539 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0063645 CE3-1 "Calcineurin enhancer, chromosome 3, group 1" http://flybase.org/reports/FBgn0063645 gene - - - CE3-1 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0013319 Pcp25 Pupal-cuticle-protein-25kD http://flybase.org/reports/FBgn0013319 - gene - - - Pcp25 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0005068 fs(2)OW209 female sterile (2) OW209 http://flybase.org/reports/FBgn0005068 - gene - - - fs(2)OW209 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065510 l(2)SH1177 lethal (2) SH1177 http://flybase.org/reports/FBgn0065510 gene - - - l(2)SH1177 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0262383 mir-284 mir-284 stem loop http://flybase.org/reports/FBgn0262383 miRNA_gene - - - "dme-mir-284, mir-284, miR-284, CR42906, CR33600, dme-miR-284, MiR-284" - CR42906 27-Aug-18 DroID_v2018_08 - - - - - - "viable,visible,lethal - all die before end of larval stage,some die during larval stage" wing FBgn0069163 mcl(3)Z1641 mcl(3)Z1641 http://flybase.org/reports/FBgn0069163 gene molecular_function ; GO:0003674 | no biological data available male meiosis ; GO:0007140 | inferred from mutant phenotype cellular_component ; GO:0005575 | no biological data available mcl(3)Z1641 - - 27-Aug-18 DroID_v2018_08 - - - - - - male fertile onion stage spermatid & nucleus FBgn0021894 l(2)k13116 lethal (2) k13116 http://flybase.org/reports/FBgn0021894 - gene - - - l(2)k13116 - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0035346 CG1146 - http://flybase.org/reports/FBgn0035346 protein_coding_gene - - - CG1146 - CG1146 27-Aug-18 DroID_v2018_08 - - - - - - viable DRSC08189 E 0.732530614 0.410930236 -0.056289523 1.517949701 -0.018094121 -0.701037578 FBgn0267941 lncRNA:CR46221 - http://flybase.org/reports/FBgn0267941 non_protein_coding_gene - - - "CR46221, lincRNA.688" - CR46221 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0065684 l(2)SH0660 lethal (2) SH0660 http://flybase.org/reports/FBgn0065684 gene - - - "l(2)SH0660, l(2)SH2 0660" - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive" FBgn0085350 inaF-C inaF-C http://flybase.org/reports/FBgn0085350 protein_coding_gene channel regulator activity ; GO:0016247 | inferred from sequence or structural similarity with inaF-B regulation of membrane potential ; GO:0042391 | inferred from sequence or structural similarity with inaF-B membrane ; GO:0016020 | inferred from sequence or structural similarity with inaF-B "inaF-C, CG34321, inaF, INAF, InaF" "IPR029162:TRP-interacting helix, InaF motif" CG34321 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0034623 CG9822 - http://flybase.org/reports/FBgn0034623 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available extracellular region ; GO:0005576 | inferred from sequence model "CG9822, Agr-like" "IPR001283:Cysteine-rich secretory protein, allergen V5/Tpx-1-related, IPR014044:CAP domain, IPR034763:Venom allergen 3, insect" CG9822 27-Aug-18 DroID_v2018_08 "Drer\LOC101883528, Drer\pi15a, Drer\pi15b, Drer\r3hdml, Drer\crispld1b, Drer\glipr2l, Drer\crispld1a, Drer\glipr1b, Drer\glipr2, Drer\LOC100536500, Drer\crispld2" "Scer\PRY3, Scer\PRY1, Scer\PRY2" "Cele\scl-21, Cele\scl-5, Cele\scl-12, Cele\scl-9, Cele\scl-20, Cele\scl-15, Cele\scl-8, Cele\scl-17, Cele\scl-27, Cele\scl-2, Cele\scl-3, Cele\scl-23, Cele\scl-1, Cele\scl-19, Cele\scl-18, Cele\scl-13, Cele\scl-11, Cele\scl-10, Cele\scl-7, Cele\scl-14, Cele\scl-6" "Xtro\crispld2, Xtro\r3hdml, Xtro\MGC108118, Xtro\crisp2, Xtro\crisp1, Xtro\glipr2, Xtro\pi15, Xtro\crisp3" "Mmus\Pi15, Mmus\R3hdml, Mmus\Crisp2, Mmus\Pi16, Mmus\Clec18a, Mmus\Crispld1, Mmus\Glipr1l1, Mmus\Glipr1, Mmus\Crispld2, Mmus\Glipr2, Mmus\Glipr1l2, Mmus\Crisp4, Mmus\Crisp3, Mmus\Crisp1" "Hsap\CLEC18B, Hsap\CRISPLD1, Hsap\GLIPR1L1, Hsap\PI15, Hsap\PI16, Hsap\CRISPLD2, Hsap\CRISP1, Hsap\CLEC18C, Hsap\R3HDML, Hsap\CLEC18A, Hsap\GLIPR2, Hsap\CRISP2, Hsap\GLIPR1L2, Hsap\GLIPR1" viable FBgn0001342 l(1)1Bk lethal (1) 1Bk http://flybase.org/reports/FBgn0001342 - gene - - - "HM441, l(1)1Bk" - - 27-Aug-18 DroID_v2018_08 - - - - - - " adult stage , embryonic stage " "wild-type,lethal,recessive,lethal - all die before end of larval stage,some die during larval stage" FBgn0025494 l(3)82CDc lethal (3) 82CDc http://flybase.org/reports/FBgn0025494 - gene - - - l(3)82CDc - - 27-Aug-18 DroID_v2018_08 - - - - - - "lethal,recessive,viable" FBgn0083001 snoRNA:Psi28S-1192a snoRNA:Psi28S-1192a http://flybase.org/reports/FBgn0083001 snoRNA_gene - - - "snoRNA:Psi28S-1192a, Psi28S-1192a, psi28S-1192a, Psi 28S-1192a, CR34597" - CR34597 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0260002 snoRNA:Me28S-U2134b - http://flybase.org/reports/FBgn0260002 snoRNA_gene - - - "snoRNA:Me28S-U2134b, Me28S-Um2134b, CR34679, snoRNA:U34" - CR34679 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0037291 CG14662 - http://flybase.org/reports/FBgn0037291 protein_coding_gene molecular_function ; GO:0003674 | no biological data available biological_process ; GO:0008150 | no biological data available cellular_component ; GO:0005575 | no biological data available "CT34440, CG14662" "IPR032675:Leucine-rich repeat domain, L domain-like" CG14662 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0266133 c105 - http://flybase.org/reports/FBgn0266133 gene - gravitaxis ; GO:0042332 | inferred from mutant phenotype - c105 - - 27-Aug-18 DroID_v2018_08 - - - - - - gravitaxis defective FBgn0023120 anon-10An anon-10An http://flybase.org/reports/FBgn0023120 - gene - - - "6, anon-10An" - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0015935 eg-1 eg-1 http://flybase.org/reports/FBgn0015935 - gene - - - eg-1 - - 27-Aug-18 DroID_v2018_08 - - - - - - FBgn0052022 CG32022 - http://flybase.org/reports/FBgn0052022 protein_coding_gene - tail-anchored membrane protein insertion into ER membrane ; GO:0071816 | inferred from electronic annotation with InterPro:IPR028945 oogenesis ; GO:0048477 | inferred from mutant phenotype - "CG5950, BcDNA:AT11343, CG32022, Chd5, Wrb" IPR028945:WRB/Get1 family CG32022 27-Aug-18 DroID_v2018_08 Drer\wrb Scer\GET1 Cele\wrb-1 Xtro\wrb Mmus\Wrb Hsap\WRB viable "nurse cell,germline clone,ring canal" FBgn0085430 CG34401 - http://flybase.org/reports/FBgn0085430 protein_coding_gene zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007527 sensory perception of pain ; GO:0019233 | inferred from mutant phenotype - "CG34401, CG17757, CG7307, CG7317, CG15037, CG32542" "IPR007527:Zinc finger, SWIM-type, IPR015943:WD40/YVTN repeat-like-containing domain, IPR011990:Tetratricopeptide-like helical domain" CG34401 27-Aug-18 DroID_v2018_08 "Drer\zswim8, Drer\zswim5, Drer\zswim6" - Cele\ebax-1 "Xtro\zswim4, Xtro\zswim6, Xtro\zswim5, Xtro\zswim8" "Mmus\Zswim5, Mmus\Zswim6, Mmus\Zswim4, Mmus\Zswim8" "Hsap\ZSWIM8, Hsap\ZSWIM5, Hsap\ZSWIM6, Hsap\ZSWIM4" FBgn0051855 CG31855 - http://flybase.org/reports/FBgn0051855 protein_coding_gene - regulation of proteasomal ubiquitin-dependent protein catabolic process ; GO:0032434 | inferred from electronic annotation with InterPro:IPR033575 - "CG6537, CG31855" "IPR018276:DET1- and DDB1-associated protein 1, N-terminal, IPR033575:DET1- and DDB1-associated protein 1" CG31855 27-Aug-18 DroID_v2018_08 Drer\dda1 - Cele\F48C1.5 Xtro\dda1 Mmus\Dda1 Hsap\DDA1 viable DRSC02968 IK -1.499167095 -1.52824462 -0.10632783 0.163934937 -0.713775287 -1.672948211 FBgn0044065 GT7-45 GT7-45 http://flybase.org/reports/FBgn0044065 gene - - - GT7-45 - - 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0023415 Acp32CD Accessory gland protein 32CD http://flybase.org/reports/FBgn0023415 - protein_coding_gene hormone activity ; GO:0005179 | non-traceable author statement "multicellular organism reproduction ; GO:0032504 | inferred from expression pattern negative regulation of female receptivity, post-mating ; GO:0045434 | non-traceable author statement" extracellular space ; GO:0005615 | inferred from sequence model extracellular region ; GO:0005576 | traceable author statement extracellular region ; GO:0005576 | inferred from sequence model "CG4605, Acp32CD" - CG4605 27-Aug-18 DroID_v2018_08 - - - - - - viable FBgn0064119 CG33934 - http://flybase.org/reports/FBgn0064119 protein_coding_gene succinate transmembrane transporter activity ; GO:0015141 | inferred from biological aspect of ancestor with PANTHER:PTN000031937 citrate transmembrane transporter activity ; GO:0015137 | inferred from biological aspect of ancestor with PANTHER:PTN000031937 sodium ion transport ; GO:0006814 | inferred from electronic annotation with InterPro:IPR001898 succinate transmembrane transport ; GO:0071422 | inferred from biological aspect of ancestor with PANTHER:PTN000031937 integral component of plasma membrane ; GO:0005887 | inferred from biological aspect of ancestor with PANTHER:PTN000815082 "CG4961, CG32921-ORFB, CG32921, anon-WO0140519.217, CG33934" IPR001898:Solute carrier family 13 CG33934 27-Aug-18 DroID_v2018_08 "Drer\slc13a2, Drer\slc13a3, Drer\slc13a5a, Drer\slc13a4, Drer\slc13a5b, Drer\slc13a1" "Scer\PHO90, Scer\PHO91, Scer\PHO87" "Cele\nac-1, Cele\B0285.6, Cele\nac-2, Cele\nac-3" "Xtro\slc13a3, Xtro\slc13a1, Xtro\slc13a4, Xtro\slc13a2, Xtro\slc13a5" "Mmus\Slc13a2, Mmus\Slc13a4, Mmus\Slc13a1, Mmus\Slc13a3, Mmus\Slc13a5" "Hsap\SLC13A2, Hsap\SLC13A1, Hsap\SLC13A5, Hsap\SLC13A3, Hsap\SLC13A4" FBgn0005712 l(1)TK115 lethal (1) TK115 http://flybase.org/reports/FBgn0005712 - gene - - - "l1